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<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q1X7</accession>
    <name>E3Q1X7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_00222</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089098.1">
        <property type="nucleotide sequence ID" value="XM_008090907.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q1X7"/>
    <dbReference type="GeneID" id="24405587"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00222"/>
    <dbReference type="HOGENOM" id="CLU_2542436_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ25078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="83" mass="9309" checksum="985EFFE48CA4C55F" modified="2011-01-11" version="1">MSNTLTVPQMLAFRKWLHSLGDVTPTIPRAAEWVKGQLGKDVPEAVIRSILNRTSLQKSHQAKIRSIVDDSQGLISDFYPYVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2H7</accession>
    <name>E3Q2H7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD-specific glutamate dehydrogenase</fullName>
            <ecNumber evidence="4">1.4.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_00422</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-glutamate + NAD(+) + H2O = 2-oxoglutarate + NH4(+) + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15133"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.4.1.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.2" evidence="4"/>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089298.1">
        <property type="nucleotide sequence ID" value="XM_008091107.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2H7"/>
    <dbReference type="STRING" id="645133.E3Q2H7"/>
    <dbReference type="GeneID" id="24405787"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00422"/>
    <dbReference type="eggNOG" id="KOG2250">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005220_0_0_1"/>
    <dbReference type="OrthoDB" id="184415at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004352">
        <property type="term" value="F:glutamate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006538">
        <property type="term" value="P:L-glutamate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033524">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056365">
        <property type="entry name" value="NAD-GDH_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016210">
        <property type="entry name" value="NAD-GDH_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055480">
        <property type="entry name" value="NAD-GDH_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11606">
        <property type="entry name" value="GLUTAMATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11606:SF24">
        <property type="entry name" value="NAD-SPECIFIC GLUTAMATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23147">
        <property type="entry name" value="GDH2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23152">
        <property type="entry name" value="GDH_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000184">
        <property type="entry name" value="GDH_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00074">
        <property type="entry name" value="GLFV_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal" evidence="6">
        <location>
            <begin position="689"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="16"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ25278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1053" mass="118257" checksum="CF304DF7642B5D0A" modified="2011-01-11" version="1">MATAAPPRNKMLGQVQADSAESSRGPSPQPTHFSVPMAARSNGNGHRVLRSATVGYIAPEFGGKQEQMEQVKELIKNNGWIPDALIEEQVAWFYNELGIDDVYFEIEVPEVIASQITSLYAAKVAAFAREDKREEIRLDMEAHDHAIYIDTSEPGRTSTAGPRYEQRLEAKYLDHTGKSKFRVETFRSPGVLGASPTSKATLRCYFVYQCLFKQSPETTDPNETRLEVIADNGFLQKATSNTKQIYQEIIELAVSRTGPVIEVFDIEGSAEKRLVIAFRSRTARGLFSALSDLYHYYGVTSSRKYVEQFANGITVMSIYLRPAMNIEGNFPLLDQSIHQITKEISLLYCLPQNKLHSLFTSGELSLQETVYGHCVWVFIQHFLNRLGSEYVSLSEILDPKNQAHTALLSKLKRRLRTETFTPDYILEIIQSYPGLVRALYASFASVHLVVGPDFDRHFIAPTPAIEVLSDAKLKERITRDVSNEHEEMVMTAFRVFNNAILKTNYFTPTKVALSFRLDPSFLPEIEYPKRLYGMFLVIGAESRGFHLRFKDIARGGIRIVKSRSKEAYGINARNLFDENYGLASTQQRKNKDIPEGGSKGVILLDPKMQDRAKEAFEKYIDSILDLLLPAQTPGIKNPLVDLYGKEEIIFMGPDENTADLVDWATEHARARGAPWWKSFFTGKSPKLGGIPHDTYGMTTLSVREYVKGIYRKLNLDPSTVKKMQTGGPDGDLGSNEILLSNEKYTSIVDGSGVLVDPNGLDKEELLRLAKSRSMIANFDMAKLSKDGYRVLVDDNNVTLPTGEFISNGTSFRNTYHLRDTGLTDCFVPCGGRPESIDLISVNKIIKDGKSTIPYLVEGANLFITQDAKLRLEAAGCILYKDASANKGGVTSSSLEVLASLSFDDENFVKHMCHDARGQAPQFYQDYVKSVQAKIQENALLEFEAIWREHEQTGLPRSVLSDNLSNAITTLDEELQHSDLWKNEKIRRSVLQDALPNLLLEKIGLDTIIQRVPDSYLRAIFGSYLASRFVYQFGSQPSQFAFYDFMAKRMASVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2K8</accession>
    <name>E3Q2K8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00453</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089329.1">
        <property type="nucleotide sequence ID" value="XM_008091138.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2K8"/>
    <dbReference type="STRING" id="645133.E3Q2K8"/>
    <dbReference type="GeneID" id="24405818"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00453"/>
    <dbReference type="eggNOG" id="KOG1202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1180125_0_0_1"/>
    <dbReference type="OrthoDB" id="416786at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="235" mass="26539" checksum="B2B8D5D032956FA0" modified="2011-01-11" version="1">MPARVLGEIASGDAGVVAGHSHHEHASYATLKPANFESTKKLRPESVEEHPPPESRDTSGYISTRWASERYPEKISDKCDPPICIHRPFSITEVGQSASRRTDLQPDVHSTTHKRPTPYPKSAPGMGDLISSRQRRRQWRYSTSFTRATRGQETVPLAELGAILERETGCESGLLRMDDWVTRAESQGMTVLRERPSFHATGKPKLVHLKSKAHSRYRQTTSMDVRVINWPRARY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2X5</accession>
    <name>E3Q2X5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BRCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00098</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ24954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008088974.1">
        <property type="nucleotide sequence ID" value="XM_008090783.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2X5"/>
    <dbReference type="STRING" id="645133.E3Q2X5"/>
    <dbReference type="GeneID" id="24405463"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00098"/>
    <dbReference type="eggNOG" id="ENOG502QQZ5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048607_2_1_1"/>
    <dbReference type="OrthoDB" id="342264at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="329"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ24954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="354" mass="41475" checksum="7D7BCD25C2E7EA70" modified="2011-01-11" version="1">MVRGIFKDLVIAAAGDFPSDCPNEQAAMEWTKLRKGRFSSDLDDSVTHLVCTDKDFKDRKKNRRIKQAEKGKKKIHIVSWDWFRFSCTHNKKLREKHYDFSAVRTSEREKSRQQLKIQKKARNALIGQTWMNPDLYRIFTDKTFFEYKVDIFRTSEDEYGALHEKYELYLFESYAMPRLYWFGAKLFHKKDSGKWQARGIERTSPTPGLFKQEFQHFVKFFELKTSVRWWDRVIKAGTREKIFFNYSPPICGKPVGGSMKGDLYDKCVWSNKRWLRRWAELFGDELPANLQIEDAAKNLLDNLDDEAGEFLEAQPHCGDKASNDINCGAAESITNNSSDNKTEDEFNETTVVDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2Y0</accession>
    <name>E3Q2Y0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal Proteins L2 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_00103</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL2 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ24959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008088979.1">
        <property type="nucleotide sequence ID" value="XM_008090788.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2Y0"/>
    <dbReference type="STRING" id="645133.E3Q2Y0"/>
    <dbReference type="GeneID" id="24405468"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00103"/>
    <dbReference type="eggNOG" id="KOG2309">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036235_0_3_1"/>
    <dbReference type="OrthoDB" id="10267824at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000020">
        <property type="entry name" value="60S ribosomal protein L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.950.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000006">
        <property type="entry name" value="60S ribosomal protein L8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.950.10">
        <property type="entry name" value="Ribosomal protein L2, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002171">
        <property type="entry name" value="Ribosomal_uL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022669">
        <property type="entry name" value="Ribosomal_uL2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022671">
        <property type="entry name" value="Ribosomal_uL2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014726">
        <property type="entry name" value="Ribosomal_uL2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022666">
        <property type="entry name" value="Ribosomal_uL2_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691:SF16">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691">
        <property type="entry name" value="RIBOSOMAL PROTEIN L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03947">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00181">
        <property type="entry name" value="Ribosomal_L2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002158">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01383">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01382">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00467">
        <property type="entry name" value="RIBOSOMAL_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL2 RNA-binding" evidence="5">
        <location>
            <begin position="11"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL2 C-terminal" evidence="4">
        <location>
            <begin position="96"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ24959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="255" mass="27689" checksum="4926038B7395748A" modified="2011-01-11" version="1">MGRVIRNQRRGRGSIFTANTRLNKAPAKFRNLDYAERHGYLRGIVKDIIHDPGRGAPLAQVVFRDPYKFKQHTETFIANEGMYTGQFIYAGKKAALTVGNVLPLGSMPEGTVVSNVETKIGDRGTLGRTSGNYITIIGHNPDEGKTRIKLPSGAKKVVHSESRGMIGIVAGGGRTDKPLLKASRAKHKFAVKRGANWPRTRGVAMNPVDHPHGGGNHQHIGKASTISRYAVQGQKAGLIAARRTGLLRGTQKTKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2Y6</accession>
    <name>E3Q2Y6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA-directed RNA polymerase RBP11-like dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_00109</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ24965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008088985.1">
        <property type="nucleotide sequence ID" value="XM_008090794.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2Y6"/>
    <dbReference type="STRING" id="645133.E3Q2Y6"/>
    <dbReference type="GeneID" id="24405474"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00109"/>
    <dbReference type="eggNOG" id="KOG3438">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090381_3_2_1"/>
    <dbReference type="OrthoDB" id="510325at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055029">
        <property type="term" value="C:nuclear DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006363">
        <property type="term" value="P:termination of RNA polymerase I transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006386">
        <property type="term" value="P:termination of RNA polymerase III transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006362">
        <property type="term" value="P:transcription elongation by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006361">
        <property type="term" value="P:transcription initiation at RNA polymerase I promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006384">
        <property type="term" value="P:transcription initiation at RNA polymerase III promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd07029">
        <property type="entry name" value="RNAP_I_III_AC19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="entry name" value="RNA polymerase, RBP11-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00261">
        <property type="entry name" value="RNApol_arch_Rpo11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009025">
        <property type="entry name" value="RBP11-like_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008193">
        <property type="entry name" value="RNA_pol_Rpb11_13-16kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033898">
        <property type="entry name" value="RNAP_AC19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022905">
        <property type="entry name" value="Rpo11-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13946">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I,II,III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13946:SF28">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13656">
        <property type="entry name" value="RNA_pol_L_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="RBP11-like subunits of RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01154">
        <property type="entry name" value="RNA_POL_L_13KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase RBP11-like dimerisation" evidence="7">
        <location>
            <begin position="58"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="22"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ24965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="141" mass="15686" checksum="29802ED664486657" modified="2011-01-11" version="1">MPGRTTSEDVPMDEAPTSHQPEEEEAEAQEGSPEQEEEEEEEEPQRVKILPGSTDTAASFEFIDEGHTLGNALRYIIMKNPDVEFCAYAIPHPSEAKMNIRIQTYDGTAVSALQKGLKDLQALSDTVAEEFIRAKEEFGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3P1</accession>
    <name>E3Q3P1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00787</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089663.1">
        <property type="nucleotide sequence ID" value="XM_008091472.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3P1"/>
    <dbReference type="STRING" id="645133.E3Q3P1"/>
    <dbReference type="GeneID" id="24406152"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00787"/>
    <dbReference type="eggNOG" id="ENOG502QWA6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009942_5_0_1"/>
    <dbReference type="OrthoDB" id="3501663at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01300">
        <property type="entry name" value="YtcJ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033932">
        <property type="entry name" value="YtcJ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22642:SF20">
        <property type="entry name" value="AMIDOHYDROLASE 3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22642">
        <property type="entry name" value="IMIDAZOLONEPROPIONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase 3" evidence="2">
        <location>
            <begin position="62"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ25643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="552" mass="59983" checksum="03C773CF8F2CEAB6" modified="2011-01-11" version="1">MTASQSIVFQNGKFFRSNKAPPGQRSEANFAESLIVKDGIITYVGEASAGQVKAAVDAGARVRDVGGRTILPGLVDGHIHLTQLGQTLQKLKLDDCKSLEDMRRTIKKHAVANPDQKRIFCSGWMHFMTPEGPLASLIDDLDPRPILITAKDLHSTWANSAALEELGLDDEPDPPGGEIVRDPKTGRPSGLLSEAASMKFIPLYMARVSTPEDRISAIKTAIDDYSSAGFTGLVDMAMEEDGWSALQEYREQEKAAGRRVPVRIAAYWLILPRDDDAENVKQVERAAELARSFSLETDPDCRLVGVKLVCDGIVDGCTASLKEPYSHNGDNCDPAWSPERMGPVVEAATRLGLQVALHAIGDRTVADAIDVLERHVGRRAARASSTSRSPRPRTRGGWARLGITASVQPVHADPAILRAWPRLIGEHRCGRAFAYSEFADGGAPVAIGSDAPTAPHHIMSNLYIATTRRSAREPGLDAVVNPHFALSLCDVLAGATEGAARSCFLEDRVGSLEVGKRADLAVLDMEWDPEKALQTKVLETWFDGEQVFPFRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3Q0</accession>
    <name>E3Q3Q0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DszA family Xenobiotic compound monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00796</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NtaA/SnaA/DszA monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089672.1">
        <property type="nucleotide sequence ID" value="XM_008091481.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3Q0"/>
    <dbReference type="GeneID" id="24406161"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00796"/>
    <dbReference type="eggNOG" id="ENOG502QSR6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022256_0_0_1"/>
    <dbReference type="OrthoDB" id="8922241at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="entry name" value="Luciferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051260">
        <property type="entry name" value="Diverse_substr_monoxygenases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016215">
        <property type="entry name" value="NTA_MOA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03860">
        <property type="entry name" value="FMN_nitrolo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30011">
        <property type="entry name" value="ALKANESULFONATE MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30011:SF30">
        <property type="entry name" value="XENOBIOTIC COMPOUND MONOOXYGENASE, DSZA FAMILY (AFU_ORTHOLOGUE AFUA_6G01920)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000337">
        <property type="entry name" value="NTA_MOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="Bacterial luciferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Luciferase-like" evidence="2">
        <location>
            <begin position="43"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00033748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ25652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="494" mass="54269" checksum="F30D40F105818FDC" modified="2011-01-11" version="1">MSSENQNGVTDPKAKKKKILLNAFDMFTVGHLSFGQWRNPKDRAKDKRRDLTYWTDLAKLLDKGGFVGLFLADTFGPYDTYKGSAEPSVRTGAQWPMADPVIPVSAMAAVTKNLGFAITTSTSYEQAYVVAKRFSTLDHLTKGRFGWNIVTSWKESASKAVGLPLVEHDTRYANADEYLRLLYKLWEGSWSDTALVEDAEKGVYSDYSKIRPIHHHGVFHVDAPFLTDPSPQRTPVLFQAGTSPAGIKFGSTHAEGIFVAGLSPHVVAPRVKAIREGAIAAGRDPYSVKVFAMITPIIGKDEEDAKRKYEEALKYVLVEGGLAQFSASTGIDVSQFDLDHELTDKDVASHLQRIHSSLYNLRYRGDDVPKLTPRNLGTVAAIGGNGAMPVGTASQVADVFQEWVDIADVDGFNIGYVITPGSFEDAVEYLVPELRSRGLLPEPIPEDGPAPTFREQIYGLGQKGLRPDHPGYKYKYDSYEQTVAEEEAAKAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3W2</accession>
    <name>E3Q3W2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF1237 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00858</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089734.1">
        <property type="nucleotide sequence ID" value="XM_008091543.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3W2"/>
    <dbReference type="STRING" id="645133.E3Q3W2"/>
    <dbReference type="GeneID" id="24406223"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00858"/>
    <dbReference type="eggNOG" id="ENOG502QR7D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023537_2_0_1"/>
    <dbReference type="OrthoDB" id="7771656at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008313">
        <property type="entry name" value="GH125"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31047:SF2">
        <property type="entry name" value="DUF1237 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31047">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 157 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06824">
        <property type="entry name" value="Glyco_hydro_125"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01149">
        <property type="entry name" value="DUF1237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ25714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="665" mass="73544" checksum="03720C1E84AF87A4" modified="2011-01-11" version="1">MPAFKVLGGACLSRRVRFLAVALFFVVSMIFLRNSRLGSVGGYLNPAQASRPPQTPESGHTAAGGDAGKQTHQQDKDQNPPAAHGEPDTAADQLKADAEGEDSYRDEDEELAKPGNPAHMTPPVDCVPFEEWMRKRPGPASEGRRKFPSVRPPPECRTFRLPAMDNLITRMKEVIKDPDMYRLFENAYPMTLDSMVKWRGFANKTDEETGETRVTDQELTYVITGDIDALWLRDSAEQISPYLPLLEASQDKDSLASLWRGLINAHSRYIIISPYCHSFQPPPESGIPPTQNGAYVNNKPIPPYDPQLVFDCKWELDSLASFLKMSVSYAEKTGDWQFFSKYSWVEAVEAAVDAAGAMRLGTYSAEGKVQDSAWKFTGWTNRGSETLTNDGLGNPSKENGMIRTAFRPSDDACIYQFLVPANMMWAKYLESASEIMARLDGDKARELTGKMRAQALGIRRGIDKDAIVHKPGFGDIFAYEVDGYGSANLMDDANVPSLLAMPLWNFTRSSFQLPDPPAGAEPRDYAEVYRNTRKYVLSDANSYYMKGPVISAVGGPHVGPGKAWPMAAVIAAITAYDPISGVEDVEKEVAEQLRMILDSTAGTGVLHESVNSWNPNDWTRAWFGWANGLFGELILRIEDEEKKKGQGGTGGLLGRAGRIRLRRAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q425</accession>
    <name>E3Q425_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00481</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089357.1">
        <property type="nucleotide sequence ID" value="XM_008091166.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q425"/>
    <dbReference type="STRING" id="645133.E3Q425"/>
    <dbReference type="GeneID" id="24405846"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00481"/>
    <dbReference type="eggNOG" id="KOG0742">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004471_6_0_1"/>
    <dbReference type="OrthoDB" id="10042665at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056599">
        <property type="entry name" value="AAA_lid_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054289">
        <property type="entry name" value="DUF7025"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411:SF2">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411">
        <property type="entry name" value="FAMILY ATPASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23232">
        <property type="entry name" value="AAA_lid_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22942">
        <property type="entry name" value="DUF7025"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="2">
        <location>
            <begin position="540"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="767"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="768"/>
            <end position="786"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ25337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="786" mass="88621" checksum="8235E927D529939A" modified="2011-01-11" version="1">MLQIVDDDNASTASFEEVGVRRVPEDNQALVLKEKSNKPTADIVYVLQYLGFGGKVLDSQESVTPFDDIPNYGKSSNGSHSSSIKSILEIVTKVSTNVKMSQDPPGRGHGSYYDSSSSESEDESVAKSARVIRTYMIIHSEYLINALRAVVAYYPNIDLLEDKVTIEAPYRVIVHHREALKRYRYHQPGTHSSEYARLTAEHVDVLLQFIEQTVGESIRKEQERHQRSVPVATFDNYWMALKPGEVVYVKKNDLWEAHVLSKVFQDVEMDGRSRQLRVVSWFLEFGHNRIMRTMDQTFIRSWNGEQVVQSLSVIPASLFPGDPEAMLEKQVRLGKFYWELLQRPTYMEYDGLLVQAHSRGHGGPVSRGPSGYMTGRVICDAEGHERLSMGAPENRFAPPPPLGRPPGMVPQAPPPGRDHLPHFLPRCGCEGCDSETDRIDVSPFADLDSIKLQGSPAPINDIFYITCTKVIPGFLLGDRRWGHLNLEYLKPVVTDREAFKYLVLDEEIKMTVKALIGKFAAADSGRVTPWANDFVRNKGEGRIFLLHGAPGVGKTCTAECVAELTNRPLISLTSGDLSVNSHSVENNLSYFLELGRRFGALVLLDEADVYLERRRAKDIARNGLVSVFLRALEYYRGVLFLTTNRVQAFDAAFTSRIHVALHYKNLTDVDRERIWANNFERLDRDSNGRVRVAVSTREYAYDSRDVRALRWNGREIRNALQTALALAESDTADEGIERVCITEKHLRAVVKMSRGFRDYLRSGNVYDGDSDEAGESEGEDDEIFSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q435</accession>
    <name>E3Q435_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Autophagy protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00491</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089367.1">
        <property type="nucleotide sequence ID" value="XM_008091176.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q435"/>
    <dbReference type="STRING" id="645133.E3Q435"/>
    <dbReference type="GeneID" id="24405856"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00491"/>
    <dbReference type="eggNOG" id="ENOG502SDD8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059602_0_0_1"/>
    <dbReference type="OrthoDB" id="2103031at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="318" mass="36082" checksum="1B08B36DF35F32CD" modified="2011-01-11" version="1">MGWFDGWFGSGAPASDNPLKSLDPKLREFLERESPVKIQQQQQAQDAQNRAADAATHAHAHSQQDAAEAVARPKVPKESLFQDGRYAHLWKTYRPYSEIVAETKTDHEKLVDVLDGFKQRKNNIGRAALENCAIQQEEWVNCMKNGAWEDQMQMCRHQVQRFERCYIVQTRFLRALGYHSVQNRPAQVEEDIQMHADQLYARMIEQEKAAEAAKKEGLPVPKFDLAIPTSPSGAGPVAPEVKPRPDLEKSWKERLEKLPEAERAAEEAALRADLQANADVARKVQKLWDEQEKEKEKRKAEGNATIFDRITGVFGGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q469</accession>
    <name>E3Q469_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">beta-glucosidase</fullName>
            <ecNumber evidence="4 10">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_00525</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="4 10"/>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089401.1">
        <property type="nucleotide sequence ID" value="XM_008091210.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q469"/>
    <dbReference type="STRING" id="645133.E3Q469"/>
    <dbReference type="GeneID" id="24405890"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00525"/>
    <dbReference type="eggNOG" id="ENOG502QR4D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004542_4_1_1"/>
    <dbReference type="OrthoDB" id="47059at2759"/>
    <dbReference type="UniPathway" id="UPA00696"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.260:FF:000114">
        <property type="entry name" value="Glycoside hydrolase family 3 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000495">
        <property type="entry name" value="Periplasmic beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037524">
        <property type="entry name" value="PA14/GLEYA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011658">
        <property type="entry name" value="PA14_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF3">
        <property type="entry name" value="BETA-GLUCOSIDASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07691">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00758">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51820">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 10 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PA14" evidence="12">
        <location>
            <begin position="444"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="19"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ25381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="881" mass="97228" checksum="E2C5D3D4B846E6F4" modified="2011-01-11" version="1">MDVLSSSHEGREIEPPASPQETETTNSTPNTVFSPPHSPKQKTQQLMKDTRVAARKKLNQLTLEEKVSLLTASDFWRTKSIPSKNIPAVKTSDGPNGARGGIFVGGTKAALFPCGVSLAATWNKELLYEVGQHLADEAKARSANILLAPTVCMHRHPLGGRNFESFSEDPLLTGKLAAQYIRGLQEKGVAATIKHFVGNEQETHRLTIDSLIEERPLREIYLRPFEIAVREANPWALMSSYNLVNGVHADMHNLTLREILRGEWGYDGTVISDWGGTNSTTESIIAGCDVEFPYSSKWRFDKVIKALEEGGITRKEIDRAAENVLTLVERLKGDDMSEERPEREDNRESTRELIRTAGAEGLTLLKNDGAVLPLNPKTTKVAVIGPNANRAIAGGGGSASLNPYYKTIPLESIRAAAEQEVTFAQGCHIYKWLPVASPYCTEKSGKPGVNIDWYSGDKFEGEVVVVQRRTNSDLFLWDSAPLNETGPEWSAIATTYLMPKTTGKHTVSFMSVGPGKLYVNGTLALDLWDWTEEGEAMFDGSVDYLVEVDMEAGKPVELKVEMTNELRPLAKQKQFGITHKYGGCRIGFKEEDQVDFLQEAVEAAKAADVAVVIVGLDAEWESEGYDRQTMDLPSDGSQDRLIEAVVKANPRTVVVNQSGTPVTMPWVEQVPAIIQGWYQGQEAGNALADVLFGFKNPSGKLPSTFPKRIQDTPAYNNWPGENLKVNYGEGLYIGYRHYERADIQPLFPFGHGLSYTTFEYGRPSISTKTLAPQGTIEVVFAVSNIGPVAGSEAVQIYVRDDKSRLPRPEKELVAFEKVFLEAGETRHLHISIDKYAVGYYDTAVPGWIAEEGTFRVLIGASSADIKHSVAFDVKESFSWIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q484</accession>
    <name>E3Q484_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Bgh specific protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00540</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089416.1">
        <property type="nucleotide sequence ID" value="XM_008091225.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q484"/>
    <dbReference type="STRING" id="645133.E3Q484"/>
    <dbReference type="GeneID" id="24405905"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00540"/>
    <dbReference type="eggNOG" id="ENOG502SGHJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005073_0_0_1"/>
    <dbReference type="OrthoDB" id="5386674at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="435"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="655"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="773"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="868"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="925"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="238"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="360"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="449"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="460"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="500"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="549"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="598"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="626"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="679"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="783"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="814"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="831"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="890"/>
            <end position="899"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1033" mass="112677" checksum="3A02793A97467E59" modified="2011-01-11" version="1">MTANATAHGSTAPRRSRPKPDSLQQMLDLEHARKLERLKGHQSMPPYFHPSHLAFQQVLRQHVNEARPPQSPPRLSPFPVINAQPPAKPLVPLQSRRRESSVQLPAPKTDLLPSAMKASRRITTLPPLSISVPLPPSNTKTQIDREANPKESVEHKHKTVTFLDIVAPEEPTADDASSICHSPSWESFGQNKKKEKKNEAKMRRKEKEQIERQIEKEAKSVKKMLAAKLSKAPPSRPPNASRSISSPITSADDQLRSASAHAFYDPPPPNRLLHTRQRSDSVAMQIKAALTGHKSPIQSQPHENDGFIGGLKLDQKLQAIETGMPLRKPVPLASLTHQRANSFGPEVKVTPPAFSAPSLPRSSSYGPQTETNKHREDDDFSSKSARVSSMHIPSWSQPLVSPSAPPVPDLGNLQQWKPQEAQAKLQDLVVDNDDAELEPPSALGEFVLEQERGRRRESYVHQSRQQSREPSVTGSKDEVRVSSAKSQYPPPANRQHQPRTHPSSSGSSPLAGNFTPRNGSVTNLNVRSDQSPQAEDFTRTFRLPYTPPVQASPNQGSFDRSTSQGPSLSRTMPRERLQPTKGGTVRSFRDAARAALQKVSSPSSSKPAVSSYFTRAAKDTTVIPDSPSSSRYSTDEPSPIQAAPARLFAQTAGLTMPSRDSSARPTDRSSISSCDEGMPSSSPATTPDSSRPQSEKGLPQADEEVGTVYTEAVLVSNDTRSHRISQAAILTSSPTVSNPRISLPPQIPVQTHGAHMDELEALVAETFRRNASVVDADDSDSSQEYPTPTHTESSKSSNLATPVTSAPLMSPQEYRQEEQRQAEDVAPLMQNEPTCSVQRHPSLTKSRSSPDLVLDTSFLPKLKHQPLVPRALAPHPPPRSPKRASVSMPGINTTAQASPLSDAVWRKSIVPLKTSANPSGYLEEARMSMQGPPPPAGTPRSNRASRASILPPSGNPEPVAKMLVECCSCKFLHDLPSKVYECMANPEGKVEDRKLGVSGVITTTVKCPWCSHGMTTQCCAGYAAVIYLKEKLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4Y1</accession>
    <name>E3Q4Y1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_01290</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ26146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090166.1">
        <property type="nucleotide sequence ID" value="XM_008091975.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4Y1"/>
    <dbReference type="GeneID" id="24406655"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01290"/>
    <dbReference type="eggNOG" id="ENOG502S5IN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047851_1_0_1"/>
    <dbReference type="OrthoDB" id="5427526at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="164"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="401" mass="43452" checksum="061C51806C0B8D6B" modified="2011-01-11" version="1">MPQTPGHSRNPSSVDASYQYNSVSSSPRRRRTSRSSANDPATPLRSSFNTQYPLDISYASGGMNDGNGLGNLADELADAFSDSGDEDEYYEDDNDHETGNGDSNGKGTPNINIQETERRASAAEGIRDSGVDVACLGDDNSKAKNLSLGPPPLVQRGHRRSGSEYDGSEYGSESDLDSPGMLPSLVAKMDAVESLARRGTESNGGPTDGVFRRVTEGLRDLGSQAGVEGSATRLITAHSALTTHLTHQTRQLHNLTFPLLSPLVPPPDSETIDELLPLLIELSESMPRPTTKAYDSLTALHTLTSDLVQSLNYLSDTLHMSRQTTTTATRRLKSAKELVAEIKREEELREEGERWLNRGNWSERLAKRECAGVCGDVVGGFEEVCNGWRARLLEQASSAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q596</accession>
    <name>E3Q596_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Peptidase M43 pregnancy-associated plasma-A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_01007</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Secreted metalloproteinase that allows assimilation of proteinaceous substrates.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M43B family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089883.1">
        <property type="nucleotide sequence ID" value="XM_008091692.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q596"/>
    <dbReference type="STRING" id="645133.E3Q596"/>
    <dbReference type="GeneID" id="24406372"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01007"/>
    <dbReference type="eggNOG" id="ENOG502S819">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025346_0_0_1"/>
    <dbReference type="OrthoDB" id="536211at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008754">
        <property type="entry name" value="Peptidase_M43"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47466">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47466:SF1">
        <property type="entry name" value="METALLOPROTEASE MEP1 (AFU_ORTHOLOGUE AFUA_1G07730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05572">
        <property type="entry name" value="Peptidase_M43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="490"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M43 pregnancy-associated plasma-A" evidence="12">
        <location>
            <begin position="295"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="20"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF05572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ25863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="511" mass="55004" checksum="8C7BC8531B62C6EE" modified="2011-01-11" version="1">MQGTQARPDSARESDGIVSGQAQASVAATAGQPQISGTGVSASSTDRNASSQLSGTGTLDSGVATGTISSPELATTASFRAQPSDGFNAVNDTALRAMPESDMLTRPDVASVEELNAELAVSIPDQGMSEKNAKAIAVLETAYFEYFVTKDPAPVDVGKLSIPPSISQCQNKYADKLTNSKSFIAGVLNWVPLVSRNLRGFDNCKAVESLEVGVYFHYMRASPTAARPNELEARVKAQVDTLNEALGAVRINFRLMALNWWEPKANEDWSKVSRREHKLTEWQHRTRAPGKLVLTVWIVNGLRDGGKDDQELNGYATFPNEKLDDADGIVIEEARVQGGDATTLVHDVGHWFGLGHTFNELGQECLIQSGLTNATQTSGNRDVVFQCSQVTCAGGPAVDVNNYMSYSSCRGKTPRDGFTTDQKARMFANALQFRRGYESGECMPDGSAAVKKRSSMQDLLDGKCPDVDKQASILINVPHSSGTIPSSSTGWLWAATVAPCAFVLSFLWAFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5D0</accession>
    <name>E3Q5D0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">REJ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_01041</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089917.1">
        <property type="nucleotide sequence ID" value="XM_008091726.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5D0"/>
    <dbReference type="GeneID" id="24406406"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01041"/>
    <dbReference type="HOGENOM" id="CLU_1488896_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180224" description="REJ domain-containing protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="125"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ25897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="181" mass="18277" checksum="1D00BBEC25619215" modified="2011-01-11" version="1">MLLQPMLLLLLAPLRLPTATAAFASTSPFSRRAAASASPFSRGAATSTSSVSWSAATSASPFSRRAAASASPFSRGAATSAPSVSWSAATSASPFSRRAATSASSVSWSAPTSASYVPRSAATSASSVPRSAATSTSRTSSSTAAAAAASSTARSADSYKHSHYYPPSRDCYSHCHSLPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5M1</accession>
    <name>E3Q5M1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4</fullName>
            <ecNumber evidence="6">3.1.13.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="20">Carbon catabolite repressor protein 4</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="21">Cytoplasmic deadenylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="22">Glucose-repressible alcohol dehydrogenase transcriptional effector</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="26" type="ORF">GLRG_01132</name>
    </gene>
    <organism evidence="27">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="27" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="27">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="23">Acts as a catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. Ccr4 has 3'-5' RNase activity with a strong preference for polyadenylated substrates and also low exonuclease activity towards single-stranded DNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Exonucleolytic cleavage of poly(A) to 5'-AMP.</text>
            <dbReference type="EC" id="3.1.13.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the CCR4/nocturin family.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.4" evidence="6"/>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090008.1">
        <property type="nucleotide sequence ID" value="XM_008091817.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5M1"/>
    <dbReference type="STRING" id="645133.E3Q5M1"/>
    <dbReference type="GeneID" id="24406497"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01132"/>
    <dbReference type="eggNOG" id="KOG0620">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016428_4_0_1"/>
    <dbReference type="OrthoDB" id="428734at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030015">
        <property type="term" value="C:CCR4-NOT core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004535">
        <property type="term" value="F:poly(A)-specific ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000289">
        <property type="term" value="P:nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd09097">
        <property type="entry name" value="Deadenylase_CCR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.10.10:FF:000037">
        <property type="entry name" value="Glucose-repressible alcohol dehydrogenase transcriptional effector"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000447">
        <property type="entry name" value="Glucose-repressible alcohol dehydrogenase transcriptional effector"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050410">
        <property type="entry name" value="CCR4/nocturin_mRNA_transcr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121">
        <property type="entry name" value="CARBON CATABOLITE REPRESSOR PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121:SF100">
        <property type="entry name" value="POLY(A)-SPECIFIC RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="26" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="13 26" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0540">Nuclease</keyword>
    <keyword evidence="18" id="KW-0539">Nucleus</keyword>
    <keyword evidence="27" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0677">Repeat</keyword>
    <keyword evidence="15" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="17" id="KW-0804">Transcription</keyword>
    <keyword evidence="16" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="25">
        <location>
            <begin position="390"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="25">
        <location>
            <begin position="613"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="24">
        <location>
            <begin position="94"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="24">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="24">
        <location>
            <begin position="588"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="24">
        <location>
            <begin position="747"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="24">
        <location>
            <begin position="127"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="24">
        <location>
            <begin position="211"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00030493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00031469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00033317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00045495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="EMBL" id="EFQ25988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="768" mass="86171" checksum="3D1937FE77FF88B8" modified="2011-01-11" version="1">MADSTHYLDHPVGDLYLNSLLSKEPAATDTVLLNTLLSRFVTKDSSPNPSSIPNSRANLLGMFSQNHQQGHNSRINGGPGGRGIPMLYNYQQQQQQHHQTHLQHHQAAQAEHAAHNGNGGVMGHHSAFSSGVMGNSSPYSANGLQNGQGGATRGGQAQQITEHWAEQLRLYEESKQAHRAMTEQNQPHYYARLKASENRGIAGPPPSSGKNGDDDADDRRRPYSVEKNAKERQNWHNMDLSGQGLRNLAPALFRYQFLHDLFIASNRLQTLPPAIGQLRQLRYLNVSFNQIKELPAELGMCTYLNQLLLFDNQIHTLPFELGSLHLLDVLGIEGNPLDPDMKQEIMEKGTKSLINLLKEQAPVPLPPSPRKYITVQEDVSPALEKVKVFSWNVLCDKYATPQTYGYTPTGALNWEYRKACIFDELREKDADLLCLQEISTEAFKEEFSPELAQMDYKGVHWPKTRAKTMAEKDAQGVDGCATFYKASKWILLDKQVIEFAAIAINRPDMKNQHDVFNRVMPKDNIAVVVFLESRVTGSRIILVNGHLAWESVLADVKLIQTGILMEQITKLAEKYVRWPALKDKKPITFSATGKDGEEPPPPAKEPGPSQEYRNNTDIPLLVCGDFNSTEDSSVYELLSMGRVPPNHQELSSFQYGSFTRDGIEHPFSLRDAYAHIKNTPDEMPFTNYTPGFSDVIDYLWYSTNTLEVVDILGPPDAEYLKRVPAFPNYHFPADHIQIMAEFVIKARKDKKPPHPEPDFGSGSKGQGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5P4</accession>
    <name>E3Q5P4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Nab2-like CCCH zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_01679</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ZC3H14 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090555.1">
        <property type="nucleotide sequence ID" value="XM_008092364.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5P4"/>
    <dbReference type="STRING" id="645133.E3Q5P4"/>
    <dbReference type="GeneID" id="24407044"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01679"/>
    <dbReference type="eggNOG" id="KOG3702">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027088_1_0_1"/>
    <dbReference type="OrthoDB" id="438553at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008143">
        <property type="term" value="F:poly(A) binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043488">
        <property type="term" value="P:regulation of mRNA stability"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.340.40:FF:000001">
        <property type="entry name" value="Nuclear polyadenylated RNA-binding protein nab2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1000.40:FF:000002">
        <property type="entry name" value="Nuclear polyadenylated RNA-binding protein Nab2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.40">
        <property type="entry name" value="Nuclear abundant poly(A) RNA-bind protein 2, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055046">
        <property type="entry name" value="Nab2-like_Znf-CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040366">
        <property type="entry name" value="Nab2/ZC3H14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043094">
        <property type="entry name" value="Nab2/ZC3H14_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14738">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14738:SF29">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22683">
        <property type="entry name" value="Nab2-like_zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14608">
        <property type="entry name" value="zf-CCCH_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Nab2-like CCCH zinc finger" evidence="9">
        <location>
            <begin position="431"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="92"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="258"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF22683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ26535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="502" mass="53852" checksum="FB369ADB81FF038D" modified="2011-01-11" version="1">MTVQVVLNTPLADALSAAIQPKLVEAGWASGSDDDAALVEYIILMLVNGRTQEQIATELAADLLGLGPEDPGAVDFAAWLFQQAEHINAQLNGSQPAGSDAMSGMSQGNGDFDTDMGANDGNELNAPTGPRSMRNGPNPRGGAREKRMLGYMSKAMDRSGDSVLHRVRGNDRINSHARGPPTGPRGGMGRGGRSMNNRGVNIQAGLNAMAGMNGQHGGPPGMNPMAAAWGMPPQGQPSQMDLMAMMEQQAQMMSQLQQQLMNQSGGRGGRRGGKSLFDRTQNSRGGFGNRHHQSRDKQDTAMGEGGEGDDIDMSQPKREAPNPDETVCKYNLHCTNRDCKFAHQSPAAPPGTTVDINDVCTFGAACKNRKCVGRHPSPAARLAHQNEQDCKFFPNCTNPRCPFKHPEMPLCRNGAGCTTAGCKFTHVKVKCRFNPCKNPHCMYTHEEGQQGVFKDKVWTAEGNNDHVSERQFVDSNAQAEVILPESGGAVSQEQTSAQEVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6W8</accession>
    <name>E3Q6W8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Eukaryotic aspartyl protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_02426</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase A1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090626.1">
        <property type="nucleotide sequence ID" value="XM_008092435.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6W8"/>
    <dbReference type="STRING" id="645133.E3Q6W8"/>
    <dbReference type="MEROPS" id="A01.082"/>
    <dbReference type="GeneID" id="24407791"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02426"/>
    <dbReference type="eggNOG" id="KOG1339">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013253_9_4_1"/>
    <dbReference type="OrthoDB" id="771136at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05474">
        <property type="entry name" value="SAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033876">
        <property type="entry name" value="SAP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF65">
        <property type="entry name" value="ASPARTIC-TYPE ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7 11" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180259" evidence="9">
        <location>
            <begin position="20"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="10">
        <location>
            <begin position="63"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="107"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="493"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="107"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="493"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="511"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="523"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ26606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="559" mass="57865" checksum="98C60A1623F5FEC6" modified="2011-01-11" version="1">MRTGGIAAVVGGIVSSATALSLPSATEGKGYIAMPVRQTRLNLDHLTKRDAIEVVLKNREFYYSTDVIIGTPGQQVTVLLDTGSSELWVNPDCATAPSAAQAKQCSAAGQYNPRNSRTPPSGPTGTRRLNYGDPSAPNTQTSAEIAYYSDSITMGNGILSNQTFGVVTKSDGIATGIMGLAPDLKAGFAAGQPYSLVLNSLADQGIIGSRIFSLDLRHASSDSGALIYGGVDTGKFIGELLRVPMVNGAKGEPRLAVELTGVGMKLSNSAKTYNLAPEDRNVMIDSGTTLTRLHPSLARPILSDLKATSSSDGYWTAACSLRNSDSDTYVTFTFGRKTIRVPLSDFILDLGPSDDQCYIGLVTTTDQQILGDSMMRAGYFVFDWDNQFVHMAQASTCNQEKIVAVGKGSDAIPSGVIGLCQGPTTPDGEETLSASAVSPPASPAPAIPIFAPTVDPATVTKILDNSPAPAPTPIYVTLLSSCTALTLCPQPSTANGASPTSSYPAGGLSNGGSSTPSRNTGVSPSSAAPSDPPSAASSLTEGRLLCLLLGGLMTFAAVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q704</accession>
    <name>E3Q704_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="19">CFEM domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">GLRG_02462</name>
    </gene>
    <organism evidence="20">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090662.1">
        <property type="nucleotide sequence ID" value="XM_008092471.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q704"/>
    <dbReference type="GeneID" id="24407827"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02462"/>
    <dbReference type="eggNOG" id="ENOG502S2Z9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101422_0_0_1"/>
    <dbReference type="OrthoDB" id="3559948at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051735">
        <property type="entry name" value="CFEM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37928">
        <property type="entry name" value="CFEM DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G14090)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37928:SF2">
        <property type="entry name" value="GPI ANCHORED CFEM DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G10580)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00747">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12 15" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="6 15" id="KW-0349">Heme</keyword>
    <keyword evidence="10 15" id="KW-0408">Iron</keyword>
    <keyword evidence="14" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="9 17" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012158110" evidence="17">
        <location>
            <begin position="16"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="18">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="157"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="161"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="175"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EFQ26642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="214" mass="19469" checksum="B8F1FE0F19A63764" modified="2011-01-11" version="1">MKFTLALVAAGLVAAQNFAGQPPCAIPCLTEAIPKVGCSLTDTACQCTEEKQQALVPVAASCLLAACSSSDLTKAQSAAAAACAAFKAGGGASAPASSAAAASSAASSAAPSAAPSAASSVAASVSEAITSAVASASGNATSVASSASAAITSAANGTGSLTASRTPSRTVPTVAPSGTSASASPSTSGNAAAHGSAAVGGLALAAIAGIVAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q726</accession>
    <name>E3Q726_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type I phosphodiesterase/nucleotide pyrophosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_02484</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090684.1">
        <property type="nucleotide sequence ID" value="XM_008092493.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q726"/>
    <dbReference type="STRING" id="645133.E3Q726"/>
    <dbReference type="GeneID" id="24407849"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02484"/>
    <dbReference type="eggNOG" id="KOG2645">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017594_4_0_1"/>
    <dbReference type="OrthoDB" id="415411at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047429">
        <property type="term" value="F:nucleoside triphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017111">
        <property type="term" value="F:ribonucleoside triphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009141">
        <property type="term" value="P:nucleoside triphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16018">
        <property type="entry name" value="Enpp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.180:FF:000003">
        <property type="entry name" value="Type I phosphodiesterase/nucleotide pyrophosphatase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002591">
        <property type="entry name" value="Phosphodiest/P_Trfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10151:SF120">
        <property type="entry name" value="BIS(5'-ADENOSYL)-TRIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10151">
        <property type="entry name" value="ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01663">
        <property type="entry name" value="Phosphodiest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="640"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="751"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="664"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="704"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="716"/>
            <end position="726"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ26664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="770" mass="85849" checksum="8307C52B42B5A2D3" modified="2011-01-11" version="1">MPMRRLMTRSRTDRDNTSLLAPDTYDDDASSLHSRSDQDSDSDDDQLQLRARNSRELRAADSLLFMEEEEVETLVAETRKRQDLQRQGSGLVVPNPLKLFGRGADGQRPGSSNGSSEDLFNEKDKRQQRRSRRKQKKERLLEKAIHGEDGELMYEMEEGGMKDGSSTGDSSERDDSEEIDRHRLQMLADAKTDKRRSWRRWLFLHGMIAVGFAILVLVAWKLSLGRKSAHKVELVSNGTALFAPTTIIISLDGFRADFLQRGITPRLNTFVKEGVSPKHMLPAFPSVTFPNHYTLATGLHPESHGIVGNTFWDPDMQAEFYYTDPGRSLDPKWWKGEPFWVTAERQGIRSAVHMWPGSEAHILDVQPTFLDRFNGKEALDNKVSRILEFLDKPGMEDKTAKVEDMRPQLIAAYVPNVDADGHRYGPNSTEIRVTIEATDAMMDKIFLGLEQRNLTGIVNVIVVSDHGMATTDTTRLLQLEDLVDTSKIEHTDGWPLYGLRPKNPDDLQGLYDGLADKAKTNPNFDVYLRDVNMPERYHFSNNKRIAPLWIIPKAGWAIVTKDELEVAKAVKDGSVYSPRGLHGYDHEHPLMRAIFIARGPAFPHPPNSQIDVFQNINVYNILCDSVGLIPEPNNGTLRLPLSPIGTHKPEDTPAEPEDPVPLYTTTASEAVSSEAAAMTTSPAAQSATPVKPVQVDPVPPSSSTEAVATDGNQSEGGEDSQDADEDAVQKGKEAMKGIWDWLADKFGKVWDKLSGSKGDKESGSTEEGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q792</accession>
    <name>E3Q792_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ATP synthase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_02550</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the V-ATPase E subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090750.1">
        <property type="nucleotide sequence ID" value="XM_008092559.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q792"/>
    <dbReference type="STRING" id="645133.E3Q792"/>
    <dbReference type="GeneID" id="24407915"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02550"/>
    <dbReference type="eggNOG" id="KOG1664">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073641_0_0_1"/>
    <dbReference type="OrthoDB" id="10263003at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045121">
        <property type="term" value="C:membrane raft"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000221">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2320.30">
        <property type="entry name" value="ATP synthase, E subunit, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00311">
        <property type="entry name" value="ATP_synth_E_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038495">
        <property type="entry name" value="ATPase_E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002842">
        <property type="entry name" value="ATPase_V1_Esu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45715">
        <property type="entry name" value="ATPASE H+-TRANSPORTING V1 SUBUNIT E1A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01991">
        <property type="entry name" value="vATP-synt_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160527">
        <property type="entry name" value="V-type ATPase subunit E-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ26730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="260" mass="29339" checksum="14CB8FE2C47B199F" modified="2011-01-11" version="1">MSHQPLTDDQGGDGQVSQELRKMTAFIKQEAMEKAREIEIKANEEFAIEKSKLVRQETDAIDSQYEKKFKQAQMSQQITRSTASNKTRLKVLGARQELLDNIFEDARKKLSSATKDKGKYQATLKNLIIEGLYALAEPEVVIRARKADFDVVKKAIEDAVKEYKKEVGKDTSAKIDEPNPLPAERHVSPPRLLTYLSLCPQEQKLTKMKNSAGGVFIVGGKGKIEINNTFEERLNILQDTGLPAVRETLFGKNPNRRFTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7S9</accession>
    <name>E3Q7S9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 19">Serine/threonine-protein kinase RIO1</fullName>
            <ecNumber evidence="4 19">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">GLRG_02112</name>
    </gene>
    <organism evidence="26">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="26" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="26">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="18 27">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 22">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 19">Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4 19"/>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ26941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090961.1">
        <property type="nucleotide sequence ID" value="XM_008092770.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7S9"/>
    <dbReference type="STRING" id="645133.E3Q7S9"/>
    <dbReference type="GeneID" id="24407477"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02112"/>
    <dbReference type="eggNOG" id="KOG2270">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018693_4_0_1"/>
    <dbReference type="OrthoDB" id="205248at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05147">
        <property type="entry name" value="RIO1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000232">
        <property type="entry name" value="Serine/threonine-protein kinase RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000148">
        <property type="entry name" value="Serine/threonine-protein kinase RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051272">
        <property type="entry name" value="RIO-type_Ser/Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018934">
        <property type="entry name" value="RIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000687">
        <property type="entry name" value="RIO_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018935">
        <property type="entry name" value="RIO_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017407">
        <property type="entry name" value="Ser/Thr_kinase_Rio1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45723">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01163">
        <property type="entry name" value="RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038147">
        <property type="entry name" value="Ser/Thr_PK_RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RIO"/>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01245">
        <property type="entry name" value="RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14 19 21" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 19 21" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="8 19" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="9 19" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RIO kinase" evidence="24">
        <location>
            <begin position="139"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="39"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="466"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="23">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="23">
        <location>
            <begin position="48"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="23">
        <location>
            <begin position="74"/>
            <end position="109"/>
        </location>
    </feature>
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            <begin position="469"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="23">
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            <begin position="497"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="23">
        <location>
            <begin position="527"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="20">
        <location>
            <position position="322"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="20">
        <location>
            <position position="339"/>
        </location>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="273"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="327"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="339"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PIRNR" id="PIRNR038147"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PIRSR" id="PIRSR038147-1"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PIRSR" id="PIRSR038147-3"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SMART" id="SM00090"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EFQ26941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="550" mass="62512" checksum="1FFADE8C6C8E1F83" modified="2011-01-11" version="1">MASNESPAAPHEPPYTYLPNQGYEQTESIPVELRTVANDASAHVQHDDEAEDDGDLEDIFGEDEDIDDEEWSADSGNLTKSYNRQRMFNSNDAALPRSNAQRPTSNTKASVDDQITALSKHAAKIRLDGVKENDEKSKDKADRATSEQVLDQRTRMILLQMINRGIVSEIHGAISTGKEANVYHAILHPEGDGPNIQRAIKVYKTSILVFKDRERYITGEHRFQKGFDKSSNRKMVKLWAEKEFRNLRRIHAAGIPCPEPISLKLHVLAMGFLGDKKGWAYPRLRDANLTGDDVDQQWRNLYVQLLGLMRRIYQVCRLVHADLSEYNILYNDKKLYIIDVSQSVEPDHPRALEFLRMDIKNVGDFFRRKGVDTLSDRAIFDFVSATEGPVEEPALVEALEKLYETRPADNEEAAAEQEVDNEVFRKQYIPQTLEQVYDIEKDAAKIGQGEGDKLVYKNLLADTVVKEGEDQEEESESSEDESGSGASLASGDEDESKFDKARPRGRKHEDKEEKKQHKMAVKEAKREKRKEKIPKSVKKKLVSASSRKKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8H2</accession>
    <name>E3Q8H2_COLGM</name>
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        <recommendedName>
            <fullName evidence="4">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02355</name>
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    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EFQ27184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008093013.1"/>
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    <dbReference type="STRING" id="645133.E3Q8H2"/>
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    <dbReference type="OrthoDB" id="3468019at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="NTF2-like"/>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="166" mass="19221" checksum="7CAD66EBF5F94B55" modified="2011-01-11" version="1">MDRLAATEGVEPHDSYSRMEPFSASETAIERDLRLRIRDFYRTSDRRDQDERWLDFYTPGARAKVGAQEGETRENIRQLRTAMWSTVSARKHWLTSVVGSATEKGVHVMLRGGVRRKGLDGSEDVFSWAGSAEWVRQDGEWRMDAYRVWLDPWTEIEGELPAVSHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8Q3</accession>
    <name>E3Q8Q3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phytanoyl-CoA dioxygenase</fullName>
        </recommendedName>
    </protein>
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        <name evidence="2" type="ORF">GLRG_01912</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091437.1">
        <property type="nucleotide sequence ID" value="XM_008093246.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8Q3"/>
    <dbReference type="GeneID" id="24407277"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01912"/>
    <dbReference type="eggNOG" id="ENOG502R5WG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049199_0_0_1"/>
    <dbReference type="OrthoDB" id="445007at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31630:SF6">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31630">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="324" mass="37662" checksum="21B0DB08B235E59C" modified="2011-01-11" version="1">MAKDLLTPKTNYGDWRDFFFEHGYVILKNAISAERAEHFKTKQIEWLKSFSRGFDPDNEDTWTSEHLPVSFKGGMYGSYCAPHERFAWETRMEPGVINPFIQIWETDELLSSFDMFNITLPRQRDLKWSPWPHCDQDPKRKGLQCVQGLVNFAPNGDNDGGLIVMDGSAKLFDQFFQETRVMANHEDAPPPEENYRDLFIFKEEDVAWFEKRGCKLLKPNLDPGDMVLWDSRTMHYAKHPEGTQIRHAQYVCFTPAKFADPQSLKEKADIFREWGGTTHWPHTNIHPQGKAKRNGVVDPQERDEPLEKPVITDRLLQLAAVKAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8T1</accession>
    <name>E3Q8T1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_01940</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091465.1">
        <property type="nucleotide sequence ID" value="XM_008093274.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8T1"/>
    <dbReference type="GeneID" id="24407305"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01940"/>
    <dbReference type="eggNOG" id="ENOG502SSBI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_537470_0_0_1"/>
    <dbReference type="OrthoDB" id="4656735at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ27445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="507" mass="57020" checksum="8167328C3F4E83EF" modified="2011-01-11" version="1">MASDTQTAICLDIAVDHRIRKLLKPVPRYATDTSTHVSRLEQEGRSLRLPRAEIQVTAQLAGPPVKGGIVVMLQQPRHNHPFEEGLGAVIDNCETLRALEDIFTVVSRGTLDFRKDVAVIDLLPYVSGDPRDVDDTRLKNAFRTSTATICDKRPDVLLCAGKIMMPLGRAKTVKGDSYKFENIGIGEQFGRVPKWQVRALVRPEGQHYQELYSETLFDVSMCVSRLIPTDQGYEVLLNSALSEKCNNASLILRQMLRLKERGWLESVAWINEAALERVAADTDQFATDTYHFVQRPAPRAARLPVETPLARMLRENLDLIFTRATVVQRREEYDFSLKDAANDFLDLAVKIETLLLNLLREKEAALYAHGQEDVLSKKLSGLTLAPIATPVTTLLPGFYRRQPSPIRMAKLPSSQVSRVNSDISSVSWGLDYFQEEKITPLAWRESPVTSSADEDTGDIRLFLRHNVNPVELFYNLFFISNLESFGQTYFIANLGSLTAYLGFFGIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q910</accession>
    <name>E3Q910_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02019</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091544.1">
        <property type="nucleotide sequence ID" value="XM_008093353.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q910"/>
    <dbReference type="STRING" id="645133.E3Q910"/>
    <dbReference type="GeneID" id="24407384"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02019"/>
    <dbReference type="eggNOG" id="ENOG502SUY1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_136928_0_0_1"/>
    <dbReference type="OrthoDB" id="3648350at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179527" evidence="1">
        <location>
            <begin position="18"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="152" mass="14979" checksum="84A6D39CB6815C83" modified="2011-01-11" version="1">MIHSIQTLIVLAGLASAELAPRQSTTGVDITALNKNVSATSGTGAVSAAGTLAPFGAIGVGCGVNWAEGQSYGGGLQSGSDSFGLGGGFTITEDTMNIGLGIGINGPQGLNTSVTYQASTNGTASIIFTSTKGVTCQETTVDGLKGFQCISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9S5</accession>
    <name>E3Q9S5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02757</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091633.1">
        <property type="nucleotide sequence ID" value="XM_008093442.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9S5"/>
    <dbReference type="GeneID" id="24408122"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02757"/>
    <dbReference type="eggNOG" id="ENOG502T9T6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1057705_0_0_1"/>
    <dbReference type="OrthoDB" id="4789938at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180335" evidence="1">
        <location>
            <begin position="19"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="247" mass="28188" checksum="0D6893C390D9C9E3" modified="2011-01-11" version="1">MWHKEMAILSAAASAVLASVDLVAATGGIANVEHGTTLPVESRILDLPAKPKRSIGPHLESKTFPHDNPFNITEEEARKHGHKIIPVESDLWDELVESSGINRDHRKNASLSKRAKCGKNWDDDDDPPNPTDWCTPIRNTGTCMLGLWVNRLVPHTGPNRGWVFDNTCEWIGENVPAAYYDWQEICSKLKYVTLFFINPDRWPYMAYAGHYYSSWDAGWELYYPGGKEGTRHPPRYYYRRYFNCSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QA56</accession>
    <name>E3QA56_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02888</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091764.1">
        <property type="nucleotide sequence ID" value="XM_008093573.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QA56"/>
    <dbReference type="STRING" id="645133.E3QA56"/>
    <dbReference type="GeneID" id="24408253"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02888"/>
    <dbReference type="eggNOG" id="ENOG502T8KM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029791_0_0_1"/>
    <dbReference type="OrthoDB" id="73875at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="409" mass="44969" checksum="B3BCD42DAC4DCAFA" modified="2011-01-11" version="1">MPALVAICSKGVAKAGKSVFKFQGKDYDVKLDKPLETKVDRGPSKPTSKAPDKPASCKGKRLEARVNLRNRDVTRVITQGPARQEVVRRICYGDTHGQACYHYKSVIDRDNKLSKLTCPGEKIGKALRPVVASYNTQHNTDWSSGWQQQDDLVCQRDEYPPADIWRSRDDKAVWIRLLPQGNNGGAGQLFGGCPENQATELIHEGYHTTENVGCRVVTITTRRVRAVEKVIELKFDRMDKMPADYGIEENPCWPKTLNNNDPGFALLNNDDWYKGAGRAQQRGYRQYYSKEPTDMFTVDANGVAKVSIYKRGEGNTTRQPTEEELLEDFGLVRCRDGSCEKEMHDLGYASLPVSGMKPTSPPETEASTTMAVALPTSLSGVLATAADVAKAAAAVITAAPEAVEGVGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAX4</accession>
    <name>E3QAX4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Heat shock factor binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_03156</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HSBP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ28012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092032.1">
        <property type="nucleotide sequence ID" value="XM_008093841.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAX4"/>
    <dbReference type="STRING" id="645133.E3QAX4"/>
    <dbReference type="GeneID" id="24408521"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03156"/>
    <dbReference type="eggNOG" id="ENOG502SFPH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_168441_3_0_1"/>
    <dbReference type="OrthoDB" id="4159489at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070370">
        <property type="term" value="P:cellular heat acclimation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009643">
        <property type="entry name" value="HS1-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19424">
        <property type="entry name" value="HEAT SHOCK FACTOR BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19424:SF0">
        <property type="entry name" value="HEAT SHOCK FACTOR BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06825">
        <property type="entry name" value="HSBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="42"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ28012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="77" mass="8112" checksum="2577EEECF4FD5170" modified="2011-01-11" version="1">MASNNPDSSATQSAVSEDPKADVNAAVEELLNTISNKFAGVSSEIFAKMDEMSRRLDNLEAALLANKDKEGGPPKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBC2</accession>
    <name>E3QBC2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">2-oxoglutarate reductase</fullName>
            <ecNumber evidence="4">1.1.1.399</ecNumber>
            <ecNumber evidence="5">1.1.1.95</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">GLRG_03304</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 19">
            <text>(2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12641"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18110"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="EC" id="1.1.1.95"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>(R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:49612"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.399"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.399" evidence="4"/>
    <dbReference type="EC" id="1.1.1.95" evidence="5"/>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ28160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092180.1">
        <property type="nucleotide sequence ID" value="XM_008093989.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBC2"/>
    <dbReference type="STRING" id="645133.E3QBC2"/>
    <dbReference type="GeneID" id="24408669"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03304"/>
    <dbReference type="eggNOG" id="KOG0068">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019796_9_1_1"/>
    <dbReference type="OrthoDB" id="1621027at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061759">
        <property type="term" value="F:2-oxoglutarate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004617">
        <property type="term" value="F:phosphoglycerate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12176">
        <property type="entry name" value="PGDH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.260:FF:000036">
        <property type="entry name" value="D-3-phosphoglycerate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000041">
        <property type="entry name" value="D-3-phosphoglycerate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050857">
        <property type="entry name" value="D-2-hydroxyacid_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008759">
        <property type="entry name" value="PRK11790.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42789">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G10090)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42789:SF1">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G10090)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00670">
        <property type="entry name" value="D_2_HYDROXYACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0520">NAD</keyword>
    <keyword evidence="8 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0718">Serine biosynthesis</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase catalytic" evidence="15">
        <location>
            <begin position="64"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="16">
        <location>
            <begin position="168"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EFQ28160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="471" mass="51079" checksum="C31672F04C090382" modified="2011-01-11" version="1">MASAKDIAGASAQSTTLEVSASLGLSTSPTVNFQSPPSSFAGAALTRRPAPKLLKPFDTQDIKILLLENVNQTGKDILAEQGYQVEALKTSLPEDQLIEKIRDVHVIGIRSKTKLTEKVLREAKNLLVVGCFCIGTNQVDLEYAAAHGIAVFNSPFANSRSVAELVIAEIITLARQLGDRSNEMHRGTWNKVSAKCWEIRGKTLGIVGYGHIGSQLSVLAEAMGMNVVYYDVVNLMALGTSRQVPTLDNLLEEADFVTLHVPELPETKKMISTAQLEKMKTGAYLINASRGSVVDIQALINAMRSGKIAGAALDVYPNEPAANGDYFNNSLNSWGEDLRSLNNIILTPHIGGSTEEAQRAIGVEVAEALVRYINQGVTLNSVNLPEVNLRSLTLDEPDHARVIYIHRNVPGVLRRVNEILGNHNVDKQISDSKGDIAYLMADVSSVKAEDIKEISDGLDSLGSRILTRVLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBF1</accession>
    <name>E3QBF1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_03434</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092310.1">
        <property type="nucleotide sequence ID" value="XM_008094119.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBF1"/>
    <dbReference type="GeneID" id="24408799"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03434"/>
    <dbReference type="HOGENOM" id="CLU_2249926_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ28290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="104" mass="11529" checksum="E4B2DEA03B9C8B63" modified="2011-01-11" version="1">MLERDGIKAPGRQTGRPMIIICYSGRKHWYIQLTSGRRDRKVDTAEGNGAPVASDAAFAGAVILDFHPILIERSENREPTWNGQHSGNYGRSFRFVAPANPCTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBH5</accession>
    <name>E3QBH5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SWR1-complex protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_03458</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SWC4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092334.1">
        <property type="nucleotide sequence ID" value="XM_008094143.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBH5"/>
    <dbReference type="STRING" id="645133.E3QBH5"/>
    <dbReference type="GeneID" id="24408823"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03458"/>
    <dbReference type="eggNOG" id="KOG2656">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018539_3_1_1"/>
    <dbReference type="OrthoDB" id="19740at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000812">
        <property type="term" value="C:Swr1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032563">
        <property type="entry name" value="DAMP1_SANT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027109">
        <property type="entry name" value="Swc4/Dmap1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12855:SF10">
        <property type="entry name" value="DNA METHYLTRANSFERASE 1-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12855">
        <property type="entry name" value="DNA METHYLTRANSFERASE 1-ASSOCIATED PROTEIN 1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16282">
        <property type="entry name" value="SANT_DAMP1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="DAMP1 SANT/Myb-like" evidence="9">
        <location>
            <begin position="129"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="94"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="336"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="514"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="348"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="528"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="552"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="575"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="598"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="630"/>
            <end position="640"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ28314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="640" mass="70245" checksum="AE3DDEB046995BC2" modified="2011-01-11" version="1">MTSSDVRDVLNLPDSHAGPRPAKKQKTSALRPNLKGLAREVQNLGGDNPIAIVPEVSIFKKRRFASRKPATKWELKPFTNSARGDNGALVLKHWKRKTPTTEESAAQGGDAEMKDAEGEQAASKPENSMFAKFNVEVDVPQYSEDQYRTNLQSDDWTKEETDYLLSLVRDFDLRWPIIWDRYDYVPEAINGEASADGDESKAIIPVPKPRTMEDLKARYYEVAAKMMAVQKPVQYMTQPEYTLHELMANFNANQEKLRKEFANNALTRSKEEAKEEESLLLEIKRILARSDRFNEERRELYNRLDYPHTDQDISAFKSSAGLQTLLQNLMNADKSKKRKSLMAADGASPSTPAAGQQTAVAASDSNANRRESIAAAAATAAPPEKPHKEPPSSVAQTPTAPAGGKKGQQQQERRKLSEAEMHVYGVTHHDRLSSGPTFRYEKINKLFTHKSNQQQLRIMNTLNELDIPPRLVMPTAPVTSQYELLLGAVNSLLDARKVTDKIDAEIKLELAKKAEREKSKQPAPDPAAESKEKEGESASQSTEEKKDKAADGEANTEAAAAETAMTDEPKTNGDAAGAEAPAATNGEGEAAVPAAATEEGKGEADKDRPARPGSSGASHKRSASVMSAGGDDKSAKRQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCH3</accession>
    <name>E3QCH3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SelT/selW/selH selenoprotein domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_03705</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092581.1">
        <property type="nucleotide sequence ID" value="XM_008094390.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCH3"/>
    <dbReference type="GeneID" id="24409070"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03705"/>
    <dbReference type="eggNOG" id="ENOG502S6UH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068510_0_0_1"/>
    <dbReference type="OrthoDB" id="60822at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011893">
        <property type="entry name" value="Selenoprotein_Rdx-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02174">
        <property type="entry name" value="CXXU_selWTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36417">
        <property type="entry name" value="SELENOPROTEIN DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G05220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36417:SF2">
        <property type="entry name" value="SELENOPROTEIN DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G05220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10262">
        <property type="entry name" value="Rdx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="108"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="169"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="209"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ28561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="225" mass="23736" checksum="C3741E141D014C9C" modified="2011-01-11" version="1">MAESTSVSAPTLLPRVAIQFCTQCKWMLRAAYFAQELLSTFSTSIGEVALQPSTGGTFVVTLTHLPAGAETASTTVLWDRKIEGGFPETKELKRRLRDVIQPDRDLGHVDRKHAKPAADTATVSDTQASDAVAAAPTMAPSAAPSASDVVSQLKKHPANANKAPAPVGGEEKGPTLSDEARDAISAARANTGQKAKTEITPAGHLPGQKYDEPPAKFSKKCEDCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCV7</accession>
    <name>E3QCV7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Nitrogen permease regulator 3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4 5">Required for meiotic nuclear division protein 11</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_03873</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 5">Mediates inactivation of the TORC1 complex in response to amino acid starvation. Required for meiotic nuclear division.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Vacuole membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the NPR3 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092749.1">
        <property type="nucleotide sequence ID" value="XM_008094558.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCV7"/>
    <dbReference type="STRING" id="645133.E3QCV7"/>
    <dbReference type="GeneID" id="24409238"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03873"/>
    <dbReference type="eggNOG" id="KOG3830">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014314_2_0_1"/>
    <dbReference type="OrthoDB" id="18648at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990130">
        <property type="term" value="C:GATOR1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034198">
        <property type="term" value="P:cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904262">
        <property type="term" value="P:negative regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010508">
        <property type="term" value="P:positive regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038202">
        <property type="term" value="P:TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056603">
        <property type="entry name" value="HTH_NPRL3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005365">
        <property type="entry name" value="Npr3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13153">
        <property type="entry name" value="CGTHBA PROTEIN -14 GENE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13153:SF5">
        <property type="entry name" value="GATOR COMPLEX PROTEIN NPRL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24064">
        <property type="entry name" value="HTH_NPRL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03666">
        <property type="entry name" value="NPR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0469">Meiosis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="domain" description="GATOR1 complex protein NPRL3 C-terminal HTH" evidence="7">
        <location>
            <begin position="675"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="146"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="547"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="627"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="147"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="157"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="193"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="549"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="577"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="627"/>
            <end position="637"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU368069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF24064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ28729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="742" mass="82765" checksum="6308F1C64F333479" modified="2011-01-11" version="1">MAPPVLPNPSNFLAVALVINRSRDGPNFVFHYPPHVLPPNTQSNNHEQADASAEYDDILLERLNQPGLLDADNNGDDLQQWTAGDDHLITDEGIQIVPWEYVAGFPTKDLASILTPGRAYHKKLFQLSLDPLYCVSYPIHVPESGTWKKKKKKKGKTERAKSVRTEESAVLVDLDPNEDSQDAPNGADALQAESKEEEKSLPDEADDKRASMTMFNLVFILNPKKHEAKELIATLYLNIIKKVNKAYKYCQQHSEFVWKESKRISALKDKGREDKRKMSSLWNEILATSSLAASVQDIYEAVSQNKIAALQLDTAAGPITPSVQIPVPFYITDLHNYGQTEQRGLWLTTANSFIGEDTIDEPGFLDRNFALLLMGDEKKIIAELQADPDPSTVAMVEFARLSKPTQSFYLVGQSNVLTLSQVRKYAQHFIFWRRAIAIPPLHARDVYIMSPNCDTRNLPKASFEWQKAFPLAPPLTNFLAELSYAPRPYKHFCPSKAHRPTYLDMLAWLMRGAWVTQLCTFAYVVVWPEIIYEVEHKIESDELRNAEDASSLSTSSNTLASPGPDIADEHSEVDGDISGGMGGSGSSSGGGDGNNNNNNNGGGIGAHVPTQIEQAAEKARLERIAEKTQREAAEKATAHARKMPPSATDHPSTNDAPHLARVSPYIIVDAKKATGKESLYLAAITRRLGRDPKVAKAWQAFWKYFNGQTALERIALQEDMKRKEAWNLLTAMSEHLLCVRHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>E3QD84</accession>
    <name>E3QD84_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Autophagy-related protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_04000</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Preautophagosomal structure membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHEK2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092876.1">
        <property type="nucleotide sequence ID" value="XM_008094685.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QD84"/>
    <dbReference type="STRING" id="645133.E3QD84"/>
    <dbReference type="GeneID" id="24409365"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04000"/>
    <dbReference type="eggNOG" id="KOG0615">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003637_0_0_1"/>
    <dbReference type="OrthoDB" id="504170at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010506">
        <property type="term" value="P:regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000470">
        <property type="entry name" value="Serine/threonine-protein kinase RAD53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045269">
        <property type="entry name" value="Atg1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24348">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0072">Autophagy</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="FHA" evidence="11">
        <location>
            <begin position="110"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="285"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="634"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="924"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1192"/>
            <end position="1227"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1127"/>
            <end position="1154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1193"/>
            <end position="1207"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ28856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1227" mass="137729" checksum="74E0C33FD0A5FD64" modified="2011-01-11" version="1">MEGDGSQPTQATQNVLDPRRVGKQNSGFSDEDISDIICLLYPHSEFARREVHRIAREHSQHVVGREEADAVEPDYEQEDRADQFQLTPPNIEHAIILRLSAKTKAPLHGFLFGRNVSRCDICFANDPMKRLSNIHFRIYVNEYGVVMLEDQSTNGTFVEGTLLRAKPKNANEKCGTKRVLSHGSKIKVLMHNEQHDLEFLVRIPKRVGEYEMAYNTKLQHYFATLAGLRANHNETVVPGPGGHVDLFAAPRRPPTATTRRIALPSGTTQDNVDRFPRDWDGSGKYNRVGQIGKGAFAVVYKVTSKFDGVPYAAKELEKRRFIKNGVLDQKVENEMKIMQRVQHPNIVRYIEHFDWDNRLFIIIMEFVGGGDLGKLISSRGPLQEVSVKQMAAQLLSALAHLHENNITHRDVKPDNILISSLNPFDVKLTDFGLSKMVDNEQTFLRTFCGTLLYCAPEVYSEYAEYDDNGHRNPRNRAKRAAVGQRYDHAVDVWSLGGVLFYALTGNPPYPVKNGVSYSELLHTIMTRPLDTLPLVRQDISQQGIEFLCYMLEKRPECRATVRELQEHPWLGVHRLKPSQNGDQSFDEITDEDEELQVNASQLSLEEGQSRCLADTELPFEESVDDIERDFIEEDSEQEHGTFGPTGQGAGPRLFGEVNRSAIGSRGAVAAERLNLPVADSGVLGNESLGSEIRDSYESEDASTIIGKKSGSSGGARLSISAVEGQSEDQLRSLVENVASQSLGATDLGSDLQMKSAAASHVNGTFYNASKRKPSSVDTSDEYESRPREKPIFKRLKSEGNLDALAEEEMEEYRLLASVPQIKRLESGRQIDGPFNKMHFWGKDMSTWHLRYPEMTQLQYEMFKKAAQSRGEEFGPGKSPLWEMAFKYFPPNNGVPAMHTQSQPTVEETNRALLKRDDRKVLEGTEWDIPATAPQPEEDSLPNTLPPETQPQIIVPVSDDGPKRAVAVLESAPDSLVSGISVPVTISLMSWGRGPSNTVIYEPKTEVKIPKYALKMLLWKDGYDPSKDPTKHPWDKYPNGEGFAFYLSTKATNGILLNGCELLSYDCKNPTSPSKNWVQVYDGDEIVVWGTAADTTSQTKVVFRCFYGDSSKQRRPDAPPKLVSSSVARKMDEICSKYERKLKTAAEQRQRYSEVDKELFERKQNIERERERSRVFEEKRLEALRFVALRTVSRRGSPTSASATTVLRGQTPGLHAPSPLQEARSSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDE0</accession>
    <name>E3QDE0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">mRNA cleavage and polyadenylation specificity factor complex subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_04056</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092932.1">
        <property type="nucleotide sequence ID" value="XM_008094741.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDE0"/>
    <dbReference type="STRING" id="645133.E3QDE0"/>
    <dbReference type="GeneID" id="24409421"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04056"/>
    <dbReference type="eggNOG" id="KOG1895">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021804_0_0_1"/>
    <dbReference type="OrthoDB" id="331600at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021850">
        <property type="entry name" value="Symplekin/Pta1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032460">
        <property type="entry name" value="Symplekin/Pta1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15245:SF20">
        <property type="entry name" value="SYMPLEKIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15245">
        <property type="entry name" value="SYMPLEKIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11935">
        <property type="entry name" value="SYMPK_PTA1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Symplekin/Pta1 N-terminal" evidence="4">
        <location>
            <begin position="93"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF11935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ28912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="726" mass="80369" checksum="DC9C6FABFEB3148A" modified="2011-01-11" version="1">MAAPSPQASVSDQIRQLNDARKLVLGDVKYYPTVVKSILPIVGPTAGVELRRWGADFLAEAFSTPALPGSEKETMQLFVLDTLQTMVETPNEDPHVLRSAIQTAASIYPFAVRWIINNSYDTLTWERMVAIKTRILQIWDEAESTVRICCIKFAQRVVLAQSVANPNEPRRGDSLDISLDKIPPNHQTLDARTLDAEGAGLLDRMLSVLQENSSDVLLVDATLNCLSILIRSRPGTANRILNAVLNFNPMKLANSPMTPRTRVIVKSMEKTTRMLLIHLSKRDPHNPMGPRIQQHVERMMRMRHEIFDESGRKRAFEAQQHAGMDAKRQRVAPQVATMPQIQVTPLPPGPHSLGDVFTLTGSEGLKAFDVGTLPAAMAARISINTLIRTDAQLLAKAVEGIRGRLNTLAAQPPPQINPETAPLGVDEDDDYEPDFAAAEDNEQILNKLDGDSLIRADDTDLGLRTFKLPPPPALTPELALSAGQGSVMSLFQFVKTLEDPGKKSKSGVNRLAASTNDRESWIAIITRLASRSSAGLEEFSPKDEASSSVPRPSLGNSIRDSLYTYVLEDFRRRIDVAITWLHEEWYNDQLQKKQEGNRPLHYEKWALKLIDGFSQYLNAQDKVLTRFLGEVPELSPAILSRVKLMCRDPLVVPLALTSLLYLVMMRPPAKELALDTVQDIWTEYEDARPLAAKYLVKFRPAWLESAKAAAEGGGNPAANNATAISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDR5</accession>
    <name>E3QDR5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">DnaJ domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_04147</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093023.1">
        <property type="nucleotide sequence ID" value="XM_008094832.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDR5"/>
    <dbReference type="STRING" id="645133.E3QDR5"/>
    <dbReference type="GeneID" id="24409512"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04147"/>
    <dbReference type="eggNOG" id="KOG0712">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017633_0_2_1"/>
    <dbReference type="OrthoDB" id="550424at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10719">
        <property type="entry name" value="DnaJ_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.230.10:FF:000001">
        <property type="entry name" value="DnaJ subfamily A member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.230.10">
        <property type="entry name" value="Heat shock protein DnaJ, cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044713">
        <property type="entry name" value="DNJA1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001305">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43888">
        <property type="entry name" value="DNAJ-LIKE-2, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00684">
        <property type="entry name" value="DnaJ_CXXCXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="DnaJ/Hsp40 cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51188">
        <property type="entry name" value="ZF_CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180337" evidence="7">
        <location>
            <begin position="22"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="8">
        <location>
            <begin position="24"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="CR-type" evidence="9">
        <location>
            <begin position="146"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CR-type" evidence="6">
        <location>
            <begin position="146"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ29003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="414" mass="46273" checksum="84B1AB2A002462EC" modified="2011-01-11" version="1">MFFRGAALVLLLLCLAQLALCAEDYYNLLGISKSASDREIKSAYRKLSKKYHPDKNPGDATAKDKFVEVSEAYEALIDPESRKIYDQYGHEGLKQQQQGGGGHRHDPFDVFSRFFGGGGHFGGQGQRRGQDVNVRIGISLRDFYNGVNTEFQWDKQHICEDCDGTGSADGKVETCGVCGGRGVRIVKHQLAPGMFQQVQMQCDACGGRGQSIKHKCHTCGGARVVRKPTTVQLTVARGAARDSQIVYENEADASPDYVAGNLVVTLAEKEPGLEQDNPDRVDGTFFRRKNHDLYWTEVLSLREAWMGDWTRNLTHLDGHIVRLGRDRGQVVQPGHVETVKGEGMPVYHEDGDSVYHQTEFGNLYVDYVVVLPDQMESGMEKELWSVFQKWRGKIGVDLHKDSGRPEKPVVHDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>E3QE33</accession>
    <name>E3QE33_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">BAR domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_04265</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093141.1">
        <property type="nucleotide sequence ID" value="XM_008094950.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QE33"/>
    <dbReference type="STRING" id="645133.E3QE33"/>
    <dbReference type="GeneID" id="24409630"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04265"/>
    <dbReference type="eggNOG" id="KOG1843">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG3771">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025518_0_1_1"/>
    <dbReference type="OrthoDB" id="2159336at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043332">
        <property type="term" value="C:mating projection tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031097">
        <property type="term" value="C:medial cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990528">
        <property type="term" value="C:Rvs161p-Rvs167p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051666">
        <property type="term" value="P:actin cortical patch localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097320">
        <property type="term" value="P:plasma membrane tubulation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07599">
        <property type="entry name" value="BAR_Rvs167p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000048">
        <property type="entry name" value="BAR adaptor protein RVS167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000189">
        <property type="entry name" value="BAR adaptor protein RVS167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046982">
        <property type="entry name" value="BIN3/RVS161-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174">
        <property type="entry name" value="BRIDGING INTEGRATOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174:SF1">
        <property type="entry name" value="REDUCED VIABILITY UPON STARVATION PROTEIN 167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03114">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00721">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51021">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="BAR" evidence="8">
        <location>
            <begin position="17"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="7">
        <location>
            <begin position="373"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="274"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="353"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="149"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="300"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ29121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="432" mass="48981" checksum="3EEE9F1BEF0E30CB" modified="2011-01-11" version="1">MSFRGFQKSVIRAPQQFKSRFNIGEHTKDAVYIDSERRFQELETETKRLHDESKKYFEAINGMLSHQIEFSKAMTEIYKPISGRMSDPDSLEIRGNPEGIRACEEYEAVVKDLQETLAPELEMIESRVIRPANELLDVVKVIRKTTAKREHKKLDYDRHRQTLKKLQDKKERSAKDEKALWKAENDVEQATQEFNYFNDLLKEELPRLFELEQQFIQPLFQSFYYMQLNIFYTLHEKMQHCDIGYFDLTLDVLEAFHKKRGDIQEQAEKLSIVKFKTTGQKRPPKYGRPAIESKPQHLLTAGPSSSSAAVTTPTAPPSKFGGYTRPSEPSDIPPPYSPPATNGTSGGGLAAIAAAKSKPPPPKPKPSRLSGAPAAETVTALYDYAAQAEGDLSFRAGDVIEIVSRTKSENEWWTGKLNGKSGQFPGNYVKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEY9</accession>
    <name>E3QEY9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">V-type proton ATPase subunit C</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_04354</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.</text>
    </comment>
    <comment type="function">
        <text evidence="5">Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. Reversibly leaves the enzyme after glucose depletion, causing the catalytic subcomplex V1 to detach from the V0 section.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the V-ATPase C subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093230.1">
        <property type="nucleotide sequence ID" value="XM_008095039.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEY9"/>
    <dbReference type="STRING" id="645133.E3QEY9"/>
    <dbReference type="GeneID" id="24409719"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04354"/>
    <dbReference type="eggNOG" id="KOG2909">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017554_3_0_1"/>
    <dbReference type="OrthoDB" id="6605928at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000221">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14785">
        <property type="entry name" value="V-ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.100:FF:000002">
        <property type="entry name" value="V-type proton ATPase subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1460.10">
        <property type="entry name" value="subunit c (vma5p) of the yeast v-atpase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1180">
        <property type="entry name" value="Vacuolar atp synthase subunit c, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004907">
        <property type="entry name" value="ATPase_V1-cplx_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036132">
        <property type="entry name" value="Vac_ATP_synth_c_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10137">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10137:SF0">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03223">
        <property type="entry name" value="V-ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118203">
        <property type="entry name" value="Vacuolar ATP synthase subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00053565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ29210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="393" mass="44086" checksum="F241CB5EF6FAEA88" modified="2011-01-11" version="1">MSTKYALVSLPLGIFDSSDKEEAVASLSATISPENGNVRPFNIPDFKIGTLDALVQQADDLAKLESTCGTVVAKVADSLKSILDGDEDKISQQKMVNDKPTDQYISSFSWNRVRYRADKSLSELVDILQKELITTDNDVKSKFNQYNSVKTNFTTLQRKQTGNLATKSLTPVVDPALLIQDSEYLETHLIVVPNNAKKDFLRSYETLAPMVVPRSAVQVASDEEFTLFAATAFKKHSAEFLQKCREQKWTPRQYKYVEGGKEEEQRELDRVAREEKKTWGEALRIGRTGWSESVMIWLHVLALRVFVEAVLRYGLPLDYVSVLVKTNSKLCKKVKTALDSNYSYLGGNAFGRDKRGKITKDDAMLSSEMAAAGLGGGEGHEYTAYVYYEFDFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>E3QF41</accession>
    <name>E3QF41_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="6">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_04623</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase C19 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="6"/>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093499.1">
        <property type="nucleotide sequence ID" value="XM_008095308.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QF41"/>
    <dbReference type="STRING" id="645133.E3QF41"/>
    <dbReference type="GeneID" id="24409988"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04623"/>
    <dbReference type="eggNOG" id="KOG1872">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017549_2_0_1"/>
    <dbReference type="OrthoDB" id="333239at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061136">
        <property type="term" value="P:regulation of proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02657">
        <property type="entry name" value="Peptidase_C19A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16104">
        <property type="entry name" value="Ubl_USP14_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044635">
        <property type="entry name" value="UBP14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982:SF1">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="3 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="8">
        <location>
            <begin position="2"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="9">
        <location>
            <begin position="109"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="376"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="404"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ29479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="566" mass="62241" checksum="F62F0886EF6C53B0" modified="2011-01-11" version="1">MASIPVNVSHQGTKYQVEIDTSSNGETFKYQLYSLTGVEPERQKILVKGKQVKDDDEMSKFGLKAGATLMMMGKPSGENADLARPKEAIKFVEDMTEAEAAQQEGATPAGLTNLGNTCYLNSTLQTLRSIPELQGALTTYKSGSGGAGSSFGLTSTDIATQLTDLYKNMSETQGSIPPITFLSTLRMVYPQFAEKSKTGAGYAQQDAEEAWSQIISQLKQKLSESEGSSFIDRYMSGELQSTLEVDEQAARDGGEEPVKSSETFLKLNCHIDASVNHLRDGILAALTEKLEKKSAVLDRDTTYTKKSLISRLPKYLTVHFVRFFWKREVQKKAKIMRKVTFPHELDVVEFCTDELKRALVPVRDKVREIRKDEEDIERARKRRKTNPVDRGDIAGASGGPEGKTALEKANEKKAERSGKPAATTSDADTEMTETFKTDAEVEAEKDAALITAKKELYALLNQDLARDEGANQSGIYELRGVVTHQGASADSGHYTAYVKKTAPIDPKTGKKGEEDGNWWWFNDDKVSEVTPDKIDALAGGGESHSALICLYRAIPLPTIDNDGKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QF63</accession>
    <name>E3QF63_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosomal protein L21e</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_04645</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL21 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093521.1">
        <property type="nucleotide sequence ID" value="XM_008095330.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QF63"/>
    <dbReference type="STRING" id="645133.E3QF63"/>
    <dbReference type="GeneID" id="24410010"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04645"/>
    <dbReference type="eggNOG" id="KOG1732">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103610_0_1_1"/>
    <dbReference type="OrthoDB" id="1539250at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.70:FF:000001">
        <property type="entry name" value="60S ribosomal protein L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="6.10.250.3260:FF:000001">
        <property type="entry name" value="60S ribosomal protein L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.70">
        <property type="entry name" value="Ribosomal protein L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001147">
        <property type="entry name" value="Ribosomal_eL21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018259">
        <property type="entry name" value="Ribosomal_eL21_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036948">
        <property type="entry name" value="Ribosomal_eL21_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20981">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01157">
        <property type="entry name" value="Ribosomal_L21e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01171">
        <property type="entry name" value="RIBOSOMAL_L21E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ29501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="160" mass="18361" checksum="C7F0E8394B6167DF" modified="2011-01-11" version="1">MGHPAGLRAGTRYAFSRNFREKGMIKLSTYLREYRVGDIVDIKANGAVQKGMPHKVYHGKTGVIYNVTKSAVGIIIYKKVKHRYIEKRINIRVEHISPSRSRDDFLRRVKENAALKKQAQAEGKALQLKRLPLMPREARTVDFKENKPETVTPLPYETTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFX3</accession>
    <name>E3QFX3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_04952</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093828.1">
        <property type="nucleotide sequence ID" value="XM_008095637.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFX3"/>
    <dbReference type="GeneID" id="24410317"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04952"/>
    <dbReference type="HOGENOM" id="CLU_2454603_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ29808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="89" mass="9630" checksum="478B689021C45520" modified="2011-01-11" version="1">MPVRETWSNSKRVIESKGRNGRISTVSLSQVCRFQSSLGQSRPRERVAPPCRSSDVYGYAATDNVETGHSLSGSRACVSAAVTGRELSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGQ5</accession>
    <name>E3QGQ5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NAD dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_05187</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ30043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094063.1">
        <property type="nucleotide sequence ID" value="XM_008095872.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGQ5"/>
    <dbReference type="STRING" id="645133.E3QGQ5"/>
    <dbReference type="GeneID" id="24410552"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05187"/>
    <dbReference type="eggNOG" id="KOG1502">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_9_2_1"/>
    <dbReference type="OrthoDB" id="2735536at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05227">
        <property type="entry name" value="AR_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050425">
        <property type="entry name" value="NAD(P)_dehydrat-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366">
        <property type="entry name" value="NAD DEPENDENT EPIMERASE/DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366:SF564">
        <property type="entry name" value="STEROL-4-ALPHA-CARBOXYLATE 3-DEHYDROGENASE, DECARBOXYLATING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="3">
        <location>
            <begin position="8"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ30043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="340" mass="36941" checksum="BD1EDA4FF56BB273" modified="2011-01-11" version="1">MTSNQTLLFTGANGYIGTHIVSYALERGYNVRATARSESSLANLRALFPISAYRLSFAIVPDITEHESYKDALAGVTGIIHAASPFILNPKSNETDLLRPAINGSVAILEAARQYGPDVKHIVNVSSFASIVDMSQGYRPGYTYTEKDWNPMSYEEASKTDSGGEAYCASKALAEKAMWRWMSENQAVTFTLASVCPPWVFGPYLGTPDLDRLSESMGFLWKLVDAKEVPPTDFGGCADVRDVARALIGAIETPAAGGERFLVGGGFDWQTAADVIREEVPEVRSRVPEGRPGYGKTEERYSVDGGKAERILGLEYTPLSATLGDSIRQLLEVEKASKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGT1</accession>
    <name>E3QGT1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05213</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ30069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094089.1">
        <property type="nucleotide sequence ID" value="XM_008095898.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGT1"/>
    <dbReference type="GeneID" id="24410578"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05213"/>
    <dbReference type="eggNOG" id="ENOG502T5WK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2757627_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="70" mass="7880" checksum="4324520BC8458642" modified="2011-01-11" version="1">MPNFNGSFSPYAPRRRRSPLVVLTWVSVWLTVLTLTWWFVTRRSSSISAADREFADAVIKGKEIPPDAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGU2</accession>
    <name>E3QGU2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Ras family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_05224</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rho family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ30080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094100.1">
        <property type="nucleotide sequence ID" value="XM_008095909.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGU2"/>
    <dbReference type="STRING" id="645133.E3QGU2"/>
    <dbReference type="GeneID" id="24410589"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05224"/>
    <dbReference type="eggNOG" id="KOG0393">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041217_21_2_1"/>
    <dbReference type="OrthoDB" id="8830751at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01870">
        <property type="entry name" value="RhoA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000329">
        <property type="entry name" value="GTP-binding protein rhoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0636">Prenylation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ30080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="195" mass="21947" checksum="4DEF998B548B5A91" modified="2011-01-11" version="1">MAEIRRKLVIVGDGACGKTCLLIVFSKGTFPEVYVPTVFENYVADVEVDGKHVELALWDTAGQEDYDRLRPLSYPDSHVILICFAVDSPDSLDNVQEKWISEVLHFCQGLPIILVGCKKDLRYDSKTIEELRKTSQKPVSPEEGEEVRKKIGAYKYLECSAKTNEGVREVFEHATRAALLSRSRSSGKKHKCLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGX8</accession>
    <name>E3QGX8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glutathione hydrolase</fullName>
            <ecNumber evidence="3">2.3.2.2</ecNumber>
            <ecNumber evidence="3">3.4.19.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Gamma-glutamyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Gamma-glutamyltranspeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_05260</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>an N-terminal (5-L-glutamyl)-[peptide] + an alpha-amino acid = 5-L-glutamyl amino acid + an N-terminal L-alpha-aminoacyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:23904"/>
            <dbReference type="Rhea" id="RHEA-COMP:9780"/>
            <dbReference type="Rhea" id="RHEA-COMP:9795"/>
            <dbReference type="ChEBI" id="CHEBI:77644"/>
            <dbReference type="ChEBI" id="CHEBI:78597"/>
            <dbReference type="ChEBI" id="CHEBI:78599"/>
            <dbReference type="ChEBI" id="CHEBI:78608"/>
            <dbReference type="EC" id="2.3.2.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>an S-substituted glutathione + H2O = an S-substituted L-cysteinylglycine + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:59468"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="ChEBI" id="CHEBI:143103"/>
            <dbReference type="EC" id="3.4.19.13"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>glutathione + H2O = L-cysteinylglycine + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:28807"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:61694"/>
            <dbReference type="EC" id="3.4.19.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sulfur metabolism; glutathione metabolism.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.2" evidence="3"/>
    <dbReference type="EC" id="3.4.19.13" evidence="3"/>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ30116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094136.1">
        <property type="nucleotide sequence ID" value="XM_008095945.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGX8"/>
    <dbReference type="STRING" id="645133.E3QGX8"/>
    <dbReference type="MEROPS" id="T03.011"/>
    <dbReference type="GeneID" id="24410625"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05260"/>
    <dbReference type="eggNOG" id="KOG2410">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014813_4_0_1"/>
    <dbReference type="OrthoDB" id="1081007at2759"/>
    <dbReference type="UniPathway" id="UPA00204"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036374">
        <property type="term" value="F:glutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103068">
        <property type="term" value="F:leukotriene C4 gamma-glutamyl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006751">
        <property type="term" value="P:glutathione catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.246.130:FF:000001">
        <property type="entry name" value="Gamma-glutamyltransferase 5 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.40:FF:000008">
        <property type="entry name" value="Gamma-glutamyltranspeptidase (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043138">
        <property type="entry name" value="GGT_lsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000101">
        <property type="entry name" value="GGT_peptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043137">
        <property type="entry name" value="GGT_ssub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00066">
        <property type="entry name" value="g_glut_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11686">
        <property type="entry name" value="GAMMA GLUTAMYL TRANSPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11686:SF62">
        <property type="entry name" value="GLUTATHIONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01019">
        <property type="entry name" value="G_glu_transpept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01210">
        <property type="entry name" value="GGTRANSPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178449" description="Glutathione hydrolase" evidence="4">
        <location>
            <begin position="27"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="382"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="400"/>
            <end position="402"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="424"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="452"/>
            <end position="453"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="475"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600101-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR600101-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU368068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ30116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="571" mass="61404" checksum="45DD3A2A688F17B3" modified="2011-01-11" version="1">MKPYTPSIWPCYASLLFLAELRPISAATVPQFVFNPHSGGLGAVASEAVECSKIGRDLIAQGGNAVDALVGTTFCVGTVGMYHSGIGGGGFVVIRDADGNYESVDFRESAPAAAFQDMYKGNVEGSVRGGLAVGVPSEVRGLEYIHNKYGSLPWKTVVTPAAQLATAGFIVSKDLVRYMDSAIKDQKNFLVEDPVWAEEFAPNGTLLQLGDTIYRKRYGATLAKIAEEGPDVFYAGPIAESIVATARATNGTLTLDDLASYKVVTRPSLSTSYRGHRLVSIGAPASGAVCLNTLKIMEQFDPAESADAKLGVHRFDEALRFAYGARTLLGDPDFVDGIGPFEDTLLDEDTARDIRRRILDNQTHPVEWYNPHGTYASEGFGTSHIVTADRSGMATSLTTTVNLLFGAQIMDPLSGVILNNEMNDFSIPGVRNAFGFEPSPANFIRANKRPLSSITPVIVEHPDGTLYVTVGAAGGSRILSSTAQVTWHVLEHGRTMKEALREPRLHDQLMPNVVTFEYPFDNDTVASMLEKGHRVKWVPEGGSAVQGIIFDGGVFEAASEPRQKNSGAFTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QH06</accession>
    <name>E3QH06_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05288</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ30144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094164.1">
        <property type="nucleotide sequence ID" value="XM_008095973.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QH06"/>
    <dbReference type="STRING" id="645133.E3QH06"/>
    <dbReference type="GeneID" id="24410653"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05288"/>
    <dbReference type="eggNOG" id="ENOG502T4TN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027514_2_2_1"/>
    <dbReference type="OrthoDB" id="3251507at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027796">
        <property type="entry name" value="OTT_1508_deam-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42037">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42037:SF1">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14441">
        <property type="entry name" value="OTT_1508_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="424"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="444"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="484" mass="55043" checksum="2FF8F663C2FE2B10" modified="2011-01-11" version="1">MAYTNEKDRQLFYLSSLFGAVNESCKKMNNVTYSSGDSRGDRILSPFRSFLCKLAQVCDAEKGGDTVTALVALRAANGPGYLFASNNRKEQELESTRKFLSDLLNFVGRHPESLTEKTLKKQVLGRILEFNFSRVGFYLKQILAFVVARLRLIEANATFPHDMPSDTSARSRFLKDCVNLLKTIQGAMAPGSGFSLAMNEGAGADDPDTSYAWCQFRHHLGRLYSYRQAADSIVDACKEWPELFTGFTVTHIPSSRPKRLLLPGESLSLEGVILAAFPDRNFKAYTSQIEQLRDYGLDDHIREKLEQKPVKQTVHCEVHLQDFLVREKVVKPHEYWDDDMFIATSKPPCRLCQYYFDNLENGAVVQSAHMNVYPKWRLPDVYEGQDRSAVQRREELLKDIIEKMQQDTIRVVKEHQPEWKRNDSRTESWVWGSRQGERSDTRTSGRFSSASGTRGQGMGVEGRGFLFQMPVEVEDEYVCVGSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHE7</accession>
    <name>E3QHE7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cyclin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_05452</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697348">
        <property type="protein sequence ID" value="EFQ30308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094328.1">
        <property type="nucleotide sequence ID" value="XM_008096137.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHE7"/>
    <dbReference type="STRING" id="645133.E3QHE7"/>
    <dbReference type="GeneID" id="24410817"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05452"/>
    <dbReference type="eggNOG" id="KOG1674">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018149_3_0_1"/>
    <dbReference type="OrthoDB" id="10250320at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF10">
        <property type="entry name" value="PHO85 CYCLIN-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin N-terminal" evidence="2">
        <location>
            <begin position="84"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="286"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ30308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="381" mass="42898" checksum="055FFA82142008AE" modified="2011-01-11" version="1">MESRSYLSSSELNAAALDHFVYQPVSKSMISYLAGAAYNVIACDSALMPPASAEAYRQQQLPPTPPRTPEPRPVRSEDADLPTLEAFITQLVVSSNVQVPTLMSTLVYLTRLKSRLQPMARGLRCTTHRIFLAALILTAKYLNDSSPKNKHWATYSHANNDFSSFGFSRTEVNLMEKQLLFLLDWDLRITEEDLYRELDPFLAPIRAEIEAKHARRLARRRKQEEEMRRRQEEMYNMTTYPSPPSSRASSRSRQETPDHTRTCSGSSITPPGLCYSSSYGSSISSFAPSVASSRSQSRATTPLDNPTDEPYMYVPNGSLYDSPVEVHIEHPASTLSKRKPLLPYEISTEELRDMQDGTKAKRARMGRGMWGRVFGGAVTVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QI87</accession>
    <name>E3QI87_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Serine carboxypeptidase S28</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_05846</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S28 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094722.1">
        <property type="nucleotide sequence ID" value="XM_008096531.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QI87"/>
    <dbReference type="ESTHER" id="colgm-e3qi87">
        <property type="family name" value="Prolylcarboxypeptidase"/>
    </dbReference>
    <dbReference type="MEROPS" id="S28.004"/>
    <dbReference type="GeneID" id="24411211"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05846"/>
    <dbReference type="eggNOG" id="KOG2182">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023630_1_0_1"/>
    <dbReference type="OrthoDB" id="1735038at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070008">
        <property type="term" value="F:serine-type exopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008758">
        <property type="entry name" value="Peptidase_S28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010">
        <property type="entry name" value="PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010:SF23">
        <property type="entry name" value="SERINE PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05577">
        <property type="entry name" value="Peptidase_S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ30702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="488" mass="54744" checksum="CB6B707E9F9F790C" modified="2011-01-11" version="1">MRRKLDGLTFGGLEPRAHSGDQVNQGTFDQFLDHTNTSKGTFKQRYWWNAEHWGGPGFPVFMVNGGETNAGRLTGYLENGTLASLYAETHKGAIILIEHRYYGESWPFKTSTADTLQYLDVPQAIRDNIHFAQTADLPFDTNKGANANTSPWVLVGGSYAGALAAWTSVVAPGTFAAYHASSAVVQAIEDFWQFFTPIEQAMPQNCSTDIKLVIQQVDRVLDNGTAQEVDAMKQKFGLDTLADHADFAWYLQKPIIMWAYDPSKVLEFCDWIETSTNDGEVIEGREESGVGLEAAWTGYTSWMHKRYNEQCREEESCNLYGNAVGYNTPDDLDWSRSWVWQLCNEPLGWWHTGPSSSNGTGLVSSYVHLEHRKRQCDLRFPQTSGHKPAISKGITVSMFNEWTGGWNASYENVLFIDGEFDPWKSATMSSDYRPGGPSESTEKAPRLVVEGATHVPDFRLSKLNAKVVQQEVEIMGKWIEAWKPKEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIS4</accession>
    <name>E3QIS4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">lytic cellulose monooxygenase (C4-dehydrogenating)</fullName>
            <ecNumber evidence="11">1.14.99.56</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">GLRG_05906</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="11"/>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094782.1">
        <property type="nucleotide sequence ID" value="XM_008096591.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIS4"/>
    <dbReference type="STRING" id="645133.E3QIS4"/>
    <dbReference type="GeneID" id="24411271"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05906"/>
    <dbReference type="eggNOG" id="ENOG502SM9C">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031730_3_1_1"/>
    <dbReference type="OrthoDB" id="5985073at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11618">
        <property type="entry name" value="ChtBD1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF32">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 13" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180567" description="lytic cellulose monooxygenase (C4-dehydrogenating)" evidence="13">
        <location>
            <begin position="17"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="14">
        <location>
            <begin position="17"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="335"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="359"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00045077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EFQ30762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="504" mass="51644" checksum="993948E4D4390993" modified="2011-01-11" version="1">MKFFTAALALASAANAHTLFSELYINGKSQGDATCIRMPKDGATSTSPVAGLTSQDMACGKDGQIAAAYTCAAPGNAQLTFEFRQWPDKRQEGSIDPSHKGPCAVYVKKVDDMSSPAAGPGWFKIWDEGYDESTQKWCVDKLIDNKGLLTVELPSGLPAGYYFVRTEVLALHQAVSLRDPQYYVGCAQIYIQNGPSGALEIPSEYAVSIPGYIDGSEPGNNFNLYDNPKFPYPIPGPAPFSPTGTSSSVKAASFEGGVPGDCLIKNANWCGKAVAAYSSETGCWAGVDACYAQGNECFDSAPPTGASNCYIWNDKMCKGLEAQCRAKNFNGPPQIEMEATTSSPPGPIPAAVNLNLLGGSSNSNTGSAPAPSAAASSAPAPAPSAAASSPAAAATPVAEYAPVEPAATSKPAPTFAAVSSAAPVPATPTAAAPAAPTAANGLKISTDGTCGGETGLTCEGSKFGACCSASGKCGSKILQCRPSCGCQSKFGLCLEPSSLRKSTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIY5</accession>
    <name>E3QIY5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05967</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094843.1">
        <property type="nucleotide sequence ID" value="XM_008096652.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIY5"/>
    <dbReference type="STRING" id="645133.E3QIY5"/>
    <dbReference type="GeneID" id="24411332"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05967"/>
    <dbReference type="eggNOG" id="ENOG502RPIZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_834216_0_0_1"/>
    <dbReference type="OrthoDB" id="10350979at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="333" mass="36928" checksum="5AAFA285F7636F95" modified="2011-01-11" version="1">MAQTRMPCQAELAEMVSRQYHRFPTETLELTRKALEDPEPYRLFQHMENLISMRRIDDLLRKNAEFRGLLADMYGTRYEWLRDADLGGARWQDARESATETLAARAKESEKEPAAVEKTKRDLMVEKLVEGGDDVGRWAGVLGFVGVPFSQAEIQAAATRMKTTSAGLFTEDRAGYGAGEAREDVGGVDPTACPDGPEGTYGPSSHIGMARQLAAMSKEHIQPPPVPRAPAEGGKAPRNPFTTEWRARDAPDGWKFPATFEPYYNSNQYIRRSTKYKLPEIEQMVDGVDDNDSGDGEDPGDEAPGSVDGSDSIGWTCHCDSTQARQGNRYKIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJ13</accession>
    <name>E3QJ13_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NACHT-NTPase and P-loop NTPases N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05995</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094871.1">
        <property type="nucleotide sequence ID" value="XM_008096680.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJ13"/>
    <dbReference type="STRING" id="645133.E3QJ13"/>
    <dbReference type="GeneID" id="24411360"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05995"/>
    <dbReference type="eggNOG" id="ENOG502R95B">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080513_1_0_1"/>
    <dbReference type="OrthoDB" id="195446at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031352">
        <property type="entry name" value="SesA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17107">
        <property type="entry name" value="SesA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NACHT-NTPase and P-loop NTPases N-terminal" evidence="1">
        <location>
            <begin position="11"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="131" mass="14522" checksum="4034A4955694A37B" modified="2011-01-11" version="1">MASGFEIFGLIGTIITIIDTSIEVFGAIEDLRGLPEAFKEVNNRLPLIKEILEEAKGHAKDAPANEVKALGKTLASCQKKTKELQEIFLKIQMKAKDGEFVTSVYKALVLKLGKKSRVEDLMQNILQDFTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJ44</accession>
    <name>E3QJ44_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_06026</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094902.1">
        <property type="nucleotide sequence ID" value="XM_008096711.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJ44"/>
    <dbReference type="STRING" id="645133.E3QJ44"/>
    <dbReference type="GeneID" id="24411391"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06026"/>
    <dbReference type="eggNOG" id="KOG2614">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_19_3_1"/>
    <dbReference type="OrthoDB" id="16820at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000115">
        <property type="entry name" value="Salicylate hydroxylase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF238">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G01680)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="12"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ30882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="434" mass="48464" checksum="78CFC2D154A5F9ED" modified="2011-01-11" version="1">MTAKHIQPAVQVDIIVIGAGLSGLATAVAAAISGHRVTVFESAKELLEIGAGLQVTPNSTRILQKWGLPDRLWKSASEPTALVVHRFSGKVLAREENFDKKIRSKYQAPFIDLHRVDLQLSLYQRAKELGVQFQLGQKVDNIDFDIPELTTQSGVKATADLIVAADGLWSRSRACFLGKEDPPLATGDLAYRVVLQIDDVTDPEIREWISNPQVHFWIGPGAHGVGYSMRAEKMYNLVLLTPDDLPDGVSRQAGDVEETKVRFQEWDPIVRKLIGAVDNIEKWKLMHREEMSSWVNDKSNLVFVGDACHPMLPYLAQGANSAVEDGAVLGLLLGHLTSKSQLPKALKMYEKLRKARGESIARETFKQRHDFHLFDGPEQEARDQIFLSQLGKEPKGAFPSRWTCPEVQPWLYGYDAYVEVEKAMKTDPFSKPSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJ46</accession>
    <name>E3QJ46_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MNNG and nitrosoguanidine resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_06028</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094904.1">
        <property type="nucleotide sequence ID" value="XM_008096713.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJ46"/>
    <dbReference type="STRING" id="645133.E3QJ46"/>
    <dbReference type="GeneID" id="24411393"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06028"/>
    <dbReference type="eggNOG" id="ENOG502QUA0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020178_1_0_1"/>
    <dbReference type="OrthoDB" id="2140105at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022703">
        <property type="entry name" value="DUF3533"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053001">
        <property type="entry name" value="MNNG_permease-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34814">
        <property type="entry name" value="NITROSOGUANIDINE RESISTANCE PROTEIN SNG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34814:SF1">
        <property type="entry name" value="NITROSOGUANIDINE RESISTANCE PROTEIN SNG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12051">
        <property type="entry name" value="DUF3533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="260"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="318"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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            <begin position="330"/>
            <end position="348"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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            <begin position="387"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3533" evidence="2">
        <location>
            <begin position="5"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ30884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="456" mass="51570" checksum="B7DD5179DA57A6A8" modified="2011-01-11" version="1">MWCRNTFIICLTMFLILCLYWGIVFRINENLPSLVCFVVDFDGQVAPYDNIEPLIGPIVTNLATDTLRSPIPSIGYQIRSAGEFGFDPLKVREAVYHFEAWSAVIINPNATALLQEAVAIGNSSYDPTGAVQIITLSGRDSFMTFSYILPSITSFTSDLMKRFGTTWAEMLMANDTITKETLRRAASAVNPGVSPLMLDLRPFGPPSAIPAVTFGLSFLIAHLGFTYYLADDNKCIVPEGHPPVHYWHYVIRRWLSLMSAYFSLSLTYCLISLVFQVPFSNPPASAVEVAKNPNSYGKASFFVFWLLNFLGMAALGVACENMAMIIGPRWVGLWLTFWTLTNTLSGFWPPDIAPGFYKWAYAWPYHHVIEGSRQILFDLHSRIGLNFGVLIAWVCVNTVLFVPACYILRWKDEKEIRKKETKLPHFHLHRYDIEKAIPKQPGVEPPRRKRGFLRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJP3</accession>
    <name>E3QJP3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_06225</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697353">
        <property type="protein sequence ID" value="EFQ31081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095101.1">
        <property type="nucleotide sequence ID" value="XM_008096910.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJP3"/>
    <dbReference type="GeneID" id="24411590"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06225"/>
    <dbReference type="eggNOG" id="ENOG502SNX0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029525_2_0_1"/>
    <dbReference type="OrthoDB" id="3932667at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ31081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="620" mass="69532" checksum="29BE0D3EC9398BA7" modified="2011-01-11" version="1">MKTTRRQERQLRDRIARILPDYEDELVPVSLSLKVTKKECEKLVASILSESTSPFLSLETNDFRSGPDATSKETFRMALMKTLRPGWRDTATEARFIRLANILKQEGCAAFAGLVDAASFRHLVDDFSSLMNDAGTHAFLHSFANLIAYPRFINNPAYNDALIHPLLIAMMSYVMGGPVRMTDARGKDTPPLSVNAQDNMLHVDNTPFREEYKILLGWEKGEVKGPTGQNFTFLPGTHLGTRSIRTDKRSQPWSTENDSLFITEKSVDEVLSFQKDIIGCPPRVVEVEYPQQPITVLFNAGSLVHHRYRNNDGTTRSCVITAFHLASDHPGALIASSIDGQPKTLAGILMGHQSESNAGIFCSLLGSKALLIESKIQDILNETHHSTMIETTGMELSGEKLERWRETVIHAPSATQVKFKRGYYITLADRFISRKLLKSKLADAMAYDKHGLLDLIIYRDGHEEIRKPARKSVWTMPREGIMHVLTLWLPVVESHRFTTADVENPRVLQKEAYQIARLIRESFPSINFARESTAGKEQQLSSAQQLIVDLGESITRCEQLETYITTNLFLFLIINQTLPILDLTLRQEGIVACGIFLRAYIASVLLAESIENDAISVGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJV1</accession>
    <name>E3QJV1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_06283</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697353">
        <property type="protein sequence ID" value="EFQ31139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095159.1">
        <property type="nucleotide sequence ID" value="XM_008096968.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJV1"/>
    <dbReference type="STRING" id="645133.E3QJV1"/>
    <dbReference type="GeneID" id="24411648"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06283"/>
    <dbReference type="eggNOG" id="ENOG502QRYG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014401_1_1_1"/>
    <dbReference type="OrthoDB" id="330047at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052599">
        <property type="entry name" value="SLC43A_AATransporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20772:SF4">
        <property type="entry name" value="HYPOTHETICAL AMINO ACID TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20772">
        <property type="entry name" value="PROTEIN FMP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="165"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="194"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="224"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="377"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="419"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="446"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="469"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="495"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="535"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ31139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="589" mass="65257" checksum="782DEAF5FF885D26" modified="2011-01-11" version="1">MSLAQHVTQAEGFDYERPKDQTEDHGNREAVYSLLQPKTTETANNLEWKHLNFAPLKTYAVQKAIAAYRVSNAKRWLQVATAIVACSLAAGLVFGFAALKPVLISEGVYRKLCDADDPSLIEDGDYVPCTKQDLRLNLFFLVASVTTNVSSLIAGYVLDRYGRRACWIVSSTCLTIGCLLMATSHSIIGFDGYLLANVFLALGGTFVFVSSFQLAHAFPKHSGLIIALVTGAFDASAAVFLFYRTVYEATSGRISLKWFFFSYLSIPFLIIVAEFAYMPIHSYQTKHQLENQIERAQDDALDVHESDEEIEDTRELRKVRNDRADRRLLELNQIEEVAGDAEQREERTKTNKERQGASGVWGVLHGVPAHKQIQSPWFILILLLTIVQMLKMNYFIATIKSQYRFILGSEAEADAINRFFDFALPIGGLVSTPFIGVLLNKVSVTVTFGVLTALIIAIGALNYPPFGWAGYATVVLFVIFRPLYYSAISDYATKVFGFATFGRIYGTIVCVSGLVNFAQSGLDSFTHGPLHGDPTLVNITLGVAGAIVGVVLTVFVSIKGRAFVKQEKSAVEERRRLLSSTRQDYGSRD</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2011-04-05" modified="2025-02-05" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJV4</accession>
    <name>MEP1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName>Extracellular metalloprotease GLRG_06286</fullName>
            <ecNumber>3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="ORF">GLRG_06286</name>
    </gene>
    <organism>
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Secreted metalloproteinase that allows assimilation of proteinaceous substrates.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the peptidase M43B family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-"/>
    <dbReference type="EMBL" id="GG697353">
        <property type="protein sequence ID" value="EFQ31142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095162.1">
        <property type="nucleotide sequence ID" value="XM_008096971.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJV4"/>
    <dbReference type="SMR" id="E3QJV4"/>
    <dbReference type="STRING" id="645133.E3QJV4"/>
    <dbReference type="EnsemblFungi" id="EFQ31142">
        <property type="protein sequence ID" value="EFQ31142"/>
        <property type="gene ID" value="GLRG_06286"/>
    </dbReference>
    <dbReference type="GeneID" id="24411651"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06286"/>
    <dbReference type="eggNOG" id="ENOG502RYKG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048726_0_0_1"/>
    <dbReference type="OrthoDB" id="536211at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04275">
        <property type="entry name" value="ZnMc_pappalysin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008754">
        <property type="entry name" value="Peptidase_M43"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47466">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47466:SF1">
        <property type="entry name" value="METALLOPROTEASE MEP1 (AFU_ORTHOLOGUE AFUA_1G07730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05572">
        <property type="entry name" value="Peptidase_M43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00142">
        <property type="entry name" value="ZINC_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1015">Disulfide bond</keyword>
    <keyword id="KW-0325">Glycoprotein</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0482">Metalloprotease</keyword>
    <keyword id="KW-0645">Protease</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0964">Secreted</keyword>
    <keyword id="KW-0732">Signal</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_0000407201" description="Extracellular metalloprotease GLRG_06286">
        <location>
            <begin position="18"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="2">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="232"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="5"/>
    <sequence length="280" mass="30109" checksum="05FFB3EE54BC5349" modified="2011-01-11" version="1" precursor="true">MQVTFTLVAALAGMASAAVAGERGSFGCATHEPTLEHIEISKKLAEEEATNATLFGLAAAATITVPTYFHVVASSQTVANGYITDKMLSDQLAVMNEDFAPHGISFNLVQTTRTINPTWARDGDELAMKRSLRKGDYGALNLYFLRDIGGAFGYCYFPTTASPGSASYIRDGCTILSSTVPGGSSTNYNLGRTVTHEVGHWFGLYHTFQGGCTGSGDSIADTPAQSSPSSGCPVGRDSCPNQPGVDPIHNYMDYSIDSCYEEFTPNQQTRMYSFFNQYRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKW3</accession>
    <name>E3QKW3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">endo-polygalacturonase</fullName>
            <ecNumber evidence="3">3.2.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Pectinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">GLRG_06645</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>(1,4-alpha-D-galacturonosyl)n+m + H2O = (1,4-alpha-D-galacturonosyl)n + (1,4-alpha-D-galacturonosyl)m.</text>
            <dbReference type="EC" id="3.2.1.15"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the glycosyl hydrolase 28 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.15" evidence="3"/>
    <dbReference type="EMBL" id="GG697355">
        <property type="protein sequence ID" value="EFQ31501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095521.1">
        <property type="nucleotide sequence ID" value="XM_008097330.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKW3"/>
    <dbReference type="STRING" id="645133.E3QKW3"/>
    <dbReference type="GeneID" id="24412010"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06645"/>
    <dbReference type="eggNOG" id="ENOG502QTAW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040116_0_0_1"/>
    <dbReference type="OrthoDB" id="1546079at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004650">
        <property type="term" value="F:polygalacturonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.20.10:FF:000002">
        <property type="entry name" value="Endopolygalacturonase D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000743">
        <property type="entry name" value="Glyco_hydro_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050434">
        <property type="entry name" value="Glycosyl_hydrlase_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31884">
        <property type="entry name" value="POLYGALACTURONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31884:SF1">
        <property type="entry name" value="POLYGALACTURONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00295">
        <property type="entry name" value="Glyco_hydro_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00502">
        <property type="entry name" value="POLYGALACTURONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10 15" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 15 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 16" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179832" description="endo-polygalacturonase" evidence="16">
        <location>
            <begin position="18"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="active site" evidence="14">
        <location>
            <position position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00083621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU361169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EFQ31501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="362" mass="37064" checksum="B883C0246ED22F78" modified="2011-01-11" version="1">MVSSLLALGALVASAVAAPLDALANCTFTDAASAIKGKNSCQTIVLKDIAVPAGTTLDMTGLKSGTHVTFQGNTTFGYTLWTGPLISFSGSNIIIDGTSDHVIDCQGQRWWDGKGGNGGKVKPKFFSAQSLKNSIIRGINVLNTPVQAFSINSVTNLSVYDVTLDNSLGDTQGGHNTDAFDVGSSNGVYISGAVVKNQDDCLAINSGTNITFTGGDCSGGHGLSIGSVGGHSSNVVDTVLISNSRISNSANGVRVKTVYRATGSVSNVQYKDIALSNIANYGIVVEQDYENGKPTGHPTDGVPITNLTLSNVTGTVASSAIDVYILCATGACSDWTWTNVSVTGGISYPNCTGIPEGSGAAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QL00</accession>
    <name>E3QL00_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycine zipper domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_06827</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697356">
        <property type="protein sequence ID" value="EFQ31538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095558.1">
        <property type="nucleotide sequence ID" value="XM_008097367.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QL00"/>
    <dbReference type="GeneID" id="24412192"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06827"/>
    <dbReference type="eggNOG" id="ENOG502SQUK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067855_1_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="164" mass="16823" checksum="5F75A0C4B26AD8F0" modified="2011-01-11" version="1">MSSPSPEEKQTQRDKVIAQATAKLQEAQQEAESAQRARQRAEGVEDPEEKKKILAEAAEHEKKSKSLEKQSQRLQSGVWQGGIGGAGIGAGVGTGLGAGVGTLVGAVVGGVTAIPTTGLGLLVGAGTGAIHGPWYKLEQEKKEQAGEESDDGHEADGGDGKDAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QL98</accession>
    <name>E3QL98_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_06925</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS8 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697356">
        <property type="protein sequence ID" value="EFQ31636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095656.1">
        <property type="nucleotide sequence ID" value="XM_008097465.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QL98"/>
    <dbReference type="STRING" id="645133.E3QL98"/>
    <dbReference type="GeneID" id="24412290"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06925"/>
    <dbReference type="eggNOG" id="KOG3283">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080597_1_1_1"/>
    <dbReference type="OrthoDB" id="1703270at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11380">
        <property type="entry name" value="Ribosomal_S8e_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.290.70:FF:000001">
        <property type="entry name" value="40S ribosomal protein S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001047">
        <property type="entry name" value="Ribosomal_eS8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022309">
        <property type="entry name" value="Ribosomal_Se8/biogenesis_NSA2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00307">
        <property type="entry name" value="eS8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10394">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01201">
        <property type="entry name" value="Ribosomal_S8e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ31636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="207" mass="23438" checksum="BE0E8346A3C954CD" modified="2011-01-11" version="1">MGISRDSRHKRSASGAKRAYYRKKRAFEAGRQGANTRIGPKRIHTVRTRGGNHKYRALRLDSGNFAWASEGCTRKTRVIGVAYHPSNNELVRTNTLTKSAVVQIDAAPFRQWYEAHYGQNLGRRRQQKQQAAGTVAKEEEVKKSKSVEKKQAERFAAQGKVENALEKQFEAGRLYAVVSSRPGQSGRCDGYILEGEELAFYQRKLHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLX2</accession>
    <name>E3QLX2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DnaJ domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_07004</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095880.1">
        <property type="nucleotide sequence ID" value="XM_008097689.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLX2"/>
    <dbReference type="STRING" id="645133.E3QLX2"/>
    <dbReference type="GeneID" id="24412369"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07004"/>
    <dbReference type="eggNOG" id="KOG0691">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025145_3_1_1"/>
    <dbReference type="OrthoDB" id="552049at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016558">
        <property type="term" value="P:protein import into peroxisome matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000028">
        <property type="entry name" value="DnaJ domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026894">
        <property type="entry name" value="DnaJ_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052814">
        <property type="entry name" value="Peroxisomal_DnaJ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45006">
        <property type="entry name" value="DNAJ-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45006:SF1">
        <property type="entry name" value="DNAJ-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14308">
        <property type="entry name" value="DnaJ-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="6"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="122"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="485"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="122"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ31860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="514" mass="56352" checksum="0BB6F4806FC71158" modified="2011-01-11" version="1">MVVDTAYYDILGVQPTATDIEIKKAYRKLAIVHHPDKNPNDPSAHEKFQEIGEAYQVLSDSDLRVAYDKYGKDSAKPSEGFADPAEFFTSIFGGDAFVDWIGEISLMKDLTATMDITMQEGEEGADGEEAADGESPATEDAKKEGAKAAAGAEKTDATASTPPPAVVVEDEKEAPKAQDTTPTVADATPAAAGTTHVPTPSAAGARTPSPSPSGTSKRHQIPLRPALMDKPSDELGANAESEESLRKKEKKKGNLTKEQREQLAAYDKERARVRQERVDTLARKLLDRISVWTETDKGADVTKAFQEKTRLEVENMKMESFGLDILHAIGQTYLAKATALLRSQKFLGIGGFFSRVKDKGTIVKETWNTISSAIDAQQTIEEMARMEEKGGEEWSEERKAEYERRVTGKILTAAWRGSKFEIQSVLREVCDSVLNDKKVPLAKRLERAEALVIIGEIFSKAQRSPEEEGDYLVFEQLVAEAAIKKDKESKKKGKKTTSAEVAEDAPNVPKPEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>E3QM70</accession>
    <name>E3QM70_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA mismatch repair protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_07102</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Component of the post-replicative DNA mismatch repair system (MMR).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095978.1">
        <property type="nucleotide sequence ID" value="XM_008097787.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QM70"/>
    <dbReference type="STRING" id="645133.E3QM70"/>
    <dbReference type="GeneID" id="24412467"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07102"/>
    <dbReference type="eggNOG" id="KOG0217">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002472_1_0_1"/>
    <dbReference type="OrthoDB" id="10252754at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032301">
        <property type="term" value="C:MutSalpha complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000400">
        <property type="term" value="F:four-way junction DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032137">
        <property type="term" value="F:guanine/thymine mispair binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032138">
        <property type="term" value="F:single base insertion or deletion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043570">
        <property type="term" value="P:maintenance of DNA repeat elements"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000710">
        <property type="term" value="P:meiotic mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043111">
        <property type="term" value="P:replication fork arrest"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1420.10:FF:000014">
        <property type="entry name" value="DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1420.10:FF:000019">
        <property type="entry name" value="DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.110:FF:000006">
        <property type="entry name" value="DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1170.10:FF:000002">
        <property type="entry name" value="DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000771">
        <property type="entry name" value="DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.10">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.110">
        <property type="entry name" value="MutS, connector domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007695">
        <property type="entry name" value="DNA_mismatch_repair_MutS-lik_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017261">
        <property type="entry name" value="DNA_mismatch_repair_MutS/MSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007861">
        <property type="entry name" value="DNA_mismatch_repair_MutS_clamp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016151">
        <property type="entry name" value="DNA_mismatch_repair_MutS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007860">
        <property type="entry name" value="DNA_mmatch_repair_MutS_con_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036678">
        <property type="entry name" value="MutS_con_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003810">
        <property type="entry name" value="PRK05399.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF148">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MSH6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01624">
        <property type="entry name" value="MutS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05188">
        <property type="entry name" value="MutS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05190">
        <property type="entry name" value="MutS_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037677">
        <property type="entry name" value="DNA_mis_repair_Msh6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55271">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53150">
        <property type="entry name" value="DNA repair protein MutS, domain II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 9 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 9 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 9 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="13">
        <location>
            <begin position="1067"/>
            <end position="1083"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="125"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="274"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="803"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="874"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="14"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="38"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="183"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="218"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="274"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR037677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ31958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1229" mass="137754" checksum="101331D18BBE2FBC" modified="2011-01-11" version="1">MGERSSPAVRTPAKTPSTLTRQPSSSAGTQKTIVQFFSKSANASSRSTSKPATSAPDSSPCLRESARTNTLPRPPQPSSTTPVPSSDAIEPACSQENMVTSAVKVATRDAWPSPSTQAETVISQITSQVTGFRPPLPSSSPTRKSRKPISYAEPSDDEDDDPFVRLRASGTRRRTKTPAAIVDDGDDYEDAESNGPVDEDDDMLDFVVSDESDAPSQSKKRKRREQTKAAQPRKKPNVSSPVKEEQYDDDDIEEAMLDIPNTSTAQQWRYDPTSVAQAGTRTASKPTARRHTTLKGKEKAHLKEPEDRYPWLANIIDINKKPPGDPDYDPTTVYIPPMAWNKFSPFEKQYWEIKQKLWDTVVFFKKGKFYELYENDATIGHQLFDLKLTDRVNMRMVGVPESSLDMWVNQFVAKGYKVARVDQMESALGKEMRERDDASAKNKKVDKIIRRELACILTGGTLVDGSMLQDDLATYCASIKESIIDDKPAFGITFVDCATGQFFISEFEDDVDLTKFETFVAQISPRELILEKSRISTKALRILKNNTSPMTIWNYLKSSSEFWDADTTRRELDSGDYFATEDGRDETWPETLAQARDKDLLMSAFGSLVQYLRVLKLEGDLLSQGNFEWYTPIQRNGTLILDGQTLINLEVFSNTVNGGPEGTLFTLLNRCVTPFGKRLFRQWVCHPLCDIKKINERLDAVDMLNSDRGVREQFTSQMTKMPDLERLISRIHAASCKPEDFVRVLEGFEQIEYTMGLLGSFGGGNGLVDRLLASMPNLSEPLSYWKTAFDRKKARDERIFIPERSIEQDFDNSQDRIEDIKQELQELLGKKQSELKCKKLKFTDIGKEIYQIEAPKAVKVPSNWRQMSATSSVKRYYFEELTELVRQLQEAEETHSQIVKEVAERFFRRFDADYETWSQSIRIISQLDCLISLAKASSSLGEPSCRPQFIDQERSVVEFEELRHPCMLNAVADFIPNDIQLGGGSAKINLLTGANAAGKSTVLRMSCIAVIMAQIGCYVPATSALLTPVDRIMSRLGANDNIFASQSTFFVELSETKKILSEATPRSLVILDELGRGTSSYDGVAVAQAVLHHVATHVGCVGFFATHYHSLAAEFENHPEIRPRRMQIHVDEEQRRVTFLYKLEDGVAQGSFGMHCAAMCGISGRVIERAEVAAREWEHTSRLKESLEKAKSGCYIPLGVLSDVSSLLKGGEDVAKRGVEVLLRAVEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>E3QN00</accession>
    <name>E3QN00_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="22">Glutamate synthase [NADH]</fullName>
            <ecNumber evidence="19">1.4.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="27" type="ORF">GLRG_07382</name>
    </gene>
    <organism evidence="28">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="28" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="28">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="21">Forms L-glutamate from L-glutamine and 2-oxoglutarate. Represents an alternative pathway to L-glutamate dehydrogenase for the biosynthesis of L-glutamate. Participates with glutamine synthetase in ammonia assimilation processes. The enzyme is specific for NADH, L-glutamine and 2-oxoglutarate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>2 L-glutamate + NAD(+) = L-glutamine + 2-oxoglutarate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13753"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="1.4.1.14"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="24">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
        <text evidence="24">Binds 1 [3Fe-4S] cluster.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-glutamate biosynthesis via GLT pathway; L-glutamate from 2-oxoglutarate and L-glutamine (NAD(+) route): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Energy metabolism; nitrogen metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Nitrogen metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the glutamate synthase family.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.14" evidence="19"/>
    <dbReference type="EMBL" id="GG697360">
        <property type="protein sequence ID" value="EFQ32238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096258.1">
        <property type="nucleotide sequence ID" value="XM_008098067.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QN00"/>
    <dbReference type="GeneID" id="24412747"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07382"/>
    <dbReference type="eggNOG" id="KOG0399">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000422_8_2_1"/>
    <dbReference type="OrthoDB" id="4327079at2759"/>
    <dbReference type="UniPathway" id="UPA00045"/>
    <dbReference type="UniPathway" id="UPA00634">
        <property type="reaction ID" value="UER00690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016040">
        <property type="term" value="F:glutamate synthase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016639">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019676">
        <property type="term" value="P:ammonia assimilation cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097054">
        <property type="term" value="P:L-glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00982">
        <property type="entry name" value="gltB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00713">
        <property type="entry name" value="GltS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02808">
        <property type="entry name" value="GltS_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000160">
        <property type="entry name" value="Glutamate synthase (NADPH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1060.10:FF:000006">
        <property type="entry name" value="Glutamate synthase (NADPH/NADH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000031">
        <property type="entry name" value="Glutamate synthase 1 [NADH]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000017">
        <property type="entry name" value="Glutamate synthase [NADH], amyloplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000113">
        <property type="entry name" value="Glutamate synthase [NADH], amyloplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000022">
        <property type="entry name" value="Glutamate synthase [NADH], amyloplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.20.60:FF:000001">
        <property type="entry name" value="Glutamate synthase, large subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000001">
        <property type="entry name" value="Glutamate synthase, large subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="entry name" value="Alpha-helical ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.60">
        <property type="entry name" value="Glutamate synthase, alpha subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028261">
        <property type="entry name" value="DPD_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002489">
        <property type="entry name" value="Glu_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036485">
        <property type="entry name" value="Glu_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006982">
        <property type="entry name" value="Glu_synth_centr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012220">
        <property type="entry name" value="Glu_synth_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002932">
        <property type="entry name" value="Glu_synthdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006005">
        <property type="entry name" value="Glut_synth_ssu1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051394">
        <property type="entry name" value="Glutamate_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01317">
        <property type="entry name" value="GOGAT_sm_gam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008730">
        <property type="entry name" value="PRK11750.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43100">
        <property type="entry name" value="GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43100:SF1">
        <property type="entry name" value="GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14691">
        <property type="entry name" value="Fer4_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00310">
        <property type="entry name" value="GATase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04898">
        <property type="entry name" value="Glu_syn_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01645">
        <property type="entry name" value="Glu_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01493">
        <property type="entry name" value="GXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000187">
        <property type="entry name" value="GOGAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00419">
        <property type="entry name" value="ADXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69336">
        <property type="entry name" value="Alpha subunit of glutamate synthase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46548">
        <property type="entry name" value="alpha-helical ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="18 24" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0274">FAD</keyword>
    <keyword evidence="9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0288">FMN</keyword>
    <keyword evidence="17" id="KW-0314">Glutamate biosynthesis</keyword>
    <keyword evidence="13" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="15" id="KW-0408">Iron</keyword>
    <keyword evidence="16 24" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="28" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="26">
        <location>
            <begin position="54"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="25">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="25">
        <location>
            <begin position="960"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="25">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="active site" description="For GATase activity" evidence="23">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <feature type="binding site" evidence="24">
        <location>
            <position position="1184"/>
        </location>
        <ligand>
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="24">
        <location>
            <position position="1190"/>
        </location>
        <ligand>
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="24">
        <location>
            <position position="1195"/>
        </location>
        <ligand>
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00011233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00024383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00057049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00068518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="PIRSR" id="PIRSR000187-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="PIRSR" id="PIRSR000187-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="EMBL" id="EFQ32238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="2112" mass="233596" checksum="EA64479F6DA2C1A6" modified="2011-01-11" version="1">MGLHEDFDDRQTHIESEKEQYTPYEYQTDNNSSWAGALPVKQGLYDPSLEKDACGVGFACHIKGKPSHKIVSDARNLLCNMTHRGAVGSDARDGDGAGVMTSIPHKFFVKNFEKEEGIKLPPLGQYATGNLFFKPDEETLQESVRQLEDIAESLGLRVLGWRRPPVDSTLLGPAAKSREPIIMQPFVVLISAYGQGNAPENVDPEQFDDRLFERQLYVLRKRATHTIGLQNWFYLCSLSNKNIVYKGQLAPVQVYQYYYDLVNADYEAHFALVHSRFSTNTFPSWDRAQPLRWAAHNGEINTLRGNKNWMRAREGVMQSDIFKEELEALYPIVEDGGSDSAAFDNVLELLTINGVLSLPEAVMLMVPEAWQGNTHMDPKKAAFYEWAACQMEPWDGPALFTFADGRYCGANLDRNGLRPCRFYVMDDDRIICASEVGTMPVEPERVIQKGRLQPGRMLLVDTLAGRIIDDKELKEAVTSRQDFRAWIDKELIVLPNVLETVSKTVDVAAKPDASRLQEDPLLLSFGYTHEQVSLLLAPMASDEKEALGSMGNDAPLACLSQAPRLLYEYFRQLFAQVTNPPIDPIRESIVMSLECYVGPQGNLLEMDSSQCGRLLLPSPILSIPEFNSIKNMASIYPEWTVKTIDLTFPKSEGTEGYLRHLDYICNETTAAIENKDRIIVLSDRKTSKDRVPVSALLASGMVHHHLVSNKWRSLAAIVVETAEAREVHHMCVLLGYGADAINPYLAMECILKLNREKLIKKKLSDDALIHNYKHSCDGGILKVMSKMGISTLASYKGAQIFEALGLDETVIERCFKGTASRIQGSTFEAIAEDGFRFHERGFPSRYTVGVKGLPESGEYHWRDGGEAHMNDPTCIANIQDAVRTKNDKSYEAYSRSQYEQIKACTLRGMLDFKFEDCTPVPIEQVEPWTEIVRRFCTGAMSYGSISMESHSTLAVAMNRLGGKSNTGEGGEDPERSQRLPNGDTMRSAIKQVASGRFGVTSAYLADSDELQIKMAQGAKPGEGGELPGHKVSKSIARTRHSTPGVGLISPPPHHDIYSIEDLKQLIYDLKCSSPRSRISVKLVSEVGVGIVASGVAKAKADHILISGHDGGTGASRWTGIKYAGLPWELGLAETHQTLVLNDLRGRVVVQTDGQLRTGRDVAMACLLGAEEWGFATTPLIAMGCIFMRKCHLNSCPVGIATQDPELRKKFTGTPEHVINFFYYVANELRAIMAKLGFRTINEMVGHAEVLKVRDDLRTNKTANIDLSLLLTPAHKLRPGVATFNVRKQDHKLYVRLDNKLISEAELTLDKGLPSRIECDIVNTDRAMGTSLSYHISKRYGEDGLPLDTVHVNIKGSAGQSFGAFLAPGVTLELEGDANDYVGKGLSGGRLIVYPPRSSVFKAEENIIVGNVCLYGATKGTCFFRGVAAERFAVRNSGATAVVEGVGDHGCEYMTGGRIVILGSTGRNFAAGMSGGIAYVLDIHKDFLSKLNTEMVEAEAVEEPTEIAYLRGLIEDHHHYTGSELAARILLDFNRALPRFVKVMPVDYKRVLAEEAAKAAEAKRAEYNLPIVSGVHAKKEEKAAKLQDIEETIGDSAAEKKRALVLDKTKGFMKYQRRAEKYRNAKTRTKDWAELSSRLDEDELKYQSARCMDCGVPFCQSETGCPISNIIPKWNELVFQGQWRDALNRLLMTNNFPEFTGRVCPAPCEGACVLGINEDPVGIKSIECAIIDRGFEQGWMVPTPPEVRTGKKVAIIGSGPAGLAAADQLNRAGHTVTVYERADRPGGLLMYGIPNMKLDKRIVKRRTDFMAAEGINFKCGVAVGEDIQLMDLKAENDAVVIATGATVARDLPIKGRELEGIHYAMEFLHKNTKSLLDSELADGAYISAKDKNVIVIGGGDTGNDCIGTSVRHGAKSVINFELLPQPPPERARDNPWPQWPRIYRVDYGHTEVKQHMGKDPREYCIMSEEFVDDGTGKVKGINTIRVEWTRSATGGWDMKKVEGSQQFFPADLVLLSMGFLGPETRLFGDDIEKDARKNVKTPPGKYSTSVPGIFAAGDCRRGQSLIVWGINEGRQAAREIDLFLEQCTSLPVTGGIVKRTAQEIFKQIQPVQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QN43</accession>
    <name>E3QN43_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioesterase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07425</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697361">
        <property type="protein sequence ID" value="EFQ32281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096301.1">
        <property type="nucleotide sequence ID" value="XM_008098110.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QN43"/>
    <dbReference type="GeneID" id="24412790"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07425"/>
    <dbReference type="eggNOG" id="ENOG502T4AC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052827_4_1_1"/>
    <dbReference type="OrthoDB" id="506431at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03443">
        <property type="entry name" value="PaaI_thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052061">
        <property type="entry name" value="PTE-AB_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47260:SF6">
        <property type="entry name" value="THIOESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47260">
        <property type="entry name" value="UPF0644 PROTEIN PB2B4.06"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="1">
        <location>
            <begin position="110"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="210" mass="23116" checksum="34CC84883811F2E0" modified="2011-01-11" version="1">MVEPSKSQMAHFEAIPWVAEELSEPDLIIREPASRVFDPDLRAFEFWSSTLHSSTTIPFFVGAYHLPPESDMQALNAEDADDRIIGPQIVTRARFFLSLGRGVSTINKNLCHGGVVAAIFDECAGAICWANKAHGFLEFLPQVTQSLNISYLKPVPTMSTIAVTALLETKDGIKLVVDLMLQDKTGTVLAKAEAVFRSIKKRKKGGNEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>E3QN60</accession>
    <name>E3QN60_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Fungal specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_07442</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697361">
        <property type="protein sequence ID" value="EFQ32298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096318.1">
        <property type="nucleotide sequence ID" value="XM_008098127.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QN60"/>
    <dbReference type="STRING" id="645133.E3QN60"/>
    <dbReference type="GeneID" id="24412807"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07442"/>
    <dbReference type="eggNOG" id="ENOG502SHT0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012331_2_0_1"/>
    <dbReference type="OrthoDB" id="189997at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14653">
        <property type="entry name" value="ZIP_Gal4p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052202">
        <property type="entry name" value="Yeast_MetPath_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782:SF1">
        <property type="entry name" value="PYRIMIDINE PATHWAY REGULATORY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="26"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="121"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="121"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="140"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ32298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="682" mass="76385" checksum="DF7CE80E7EF99180" modified="2011-01-11" version="1">MPDASNSHQQAQHARQARRNPRLRLACSRCQRRKIRCDGQLPACNNCKKARVSCTDGESLRLRDLPRAQIANLKERIRWLEDIIRERCSDVDLSQGPPGDLDMQVDGDETFVPDSMIELSSGQPEANMTQQNARDVRGQSLASSESQLTTQPVRSEPRMVDTTASSTLSHEIGMVSLGSSQDSKYIGPSSGYFLARLMLTSNRQDDQTAWPTRPQAPTFTIPTALVEASHGPMPLPSKEHARQLAESYFDAINCQFPILHQPTFMNLLNQVYDSGIETDRGATGIFQVFMVLALGSAVLSRRLRARLPGESYCLSAMQHFDRLSVDSSIPGLQCLLLLTIFTMHSPSMRLNVWYLNYQCIAAVLDLGLQRDINTDSGISLLEQEMRTRIFWVVFSLDRMIATMMGRPIGLRDEACDLRLPQDIDDASLQNFEQQPQNAPPGRMAFSIHLFRLAKLNSEFKYVANSVVRKTPRYAYPAVIDINEWQREMILQLDEWYEGIPEVPGFLGIITMLYCIKMVPEVARQTPLDVLMSDFSAGLGVLAATGEHWSGAKRCRDILDDMVRATVRWIKDVTNNSSAIGCHTPRRSSRIEPTHVQTRSPYDDIAGQDGIPVARRCLSEGLSNPMTMDSMTAGVSSTLIPQDPFESFRTSFGEQLQLGDTANLDSIMRGLFDDFIPTYPSFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNF1</accession>
    <name>E3QNF1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class II Aldolase and Adducin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07533</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697361">
        <property type="protein sequence ID" value="EFQ32389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096409.1">
        <property type="nucleotide sequence ID" value="XM_008098218.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNF1"/>
    <dbReference type="STRING" id="645133.E3QNF1"/>
    <dbReference type="GeneID" id="24412898"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07533"/>
    <dbReference type="eggNOG" id="KOG3699">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006033_6_0_1"/>
    <dbReference type="OrthoDB" id="3238794at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="entry name" value="Class II aldolase/adducin N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051017">
        <property type="entry name" value="Aldolase-II_Adducin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10672">
        <property type="entry name" value="ADDUCIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10672:SF25">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 14 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="AraD/HMP-PK domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Class II aldolase/adducin N-terminal" evidence="1">
        <location>
            <begin position="4"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="222" mass="24859" checksum="8E60749F995D839F" modified="2011-01-11" version="1">MGERTGSRVFQWVWSLTTHTRVHPHAYQPNTTDCGFQNRPVNSPGFFIHSEIHKARHDVHSIRHAHTIAGRAWTVFGKPLEMITQDVCDLYGVIATMNEYSGIVTAEGEGQEIARWLGPRGKAALLLNHGLLTVGSTVDEASFLFGLLDRSCDIQLRVEAAKCGNPMLQKNIIPDELARLNFSMAGERNWLYVEAQPDIEYEIEMAGDAIRQGIDDVNVDFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNI3</accession>
    <name>E3QNI3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Succinate-semialdehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_07740</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697362">
        <property type="protein sequence ID" value="EFQ32470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096490.1">
        <property type="nucleotide sequence ID" value="XM_008098299.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNI3"/>
    <dbReference type="STRING" id="645133.E3QNI3"/>
    <dbReference type="GeneID" id="24413105"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07740"/>
    <dbReference type="eggNOG" id="KOG2451">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_5_1_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004777">
        <property type="term" value="F:succinate-semialdehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009450">
        <property type="term" value="P:gamma-aminobutyric acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050740">
        <property type="entry name" value="Aldehyde_DH_Superfamily"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353">
        <property type="entry name" value="SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353:SF5">
        <property type="entry name" value="SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="2">
        <location>
            <begin position="4"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="2">
        <location>
            <begin position="114"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ32470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="236" mass="25460" checksum="4908908F5A617C06" modified="2011-01-11" version="1">MPERLENGKASVEMKGEVVRALSIHLIVCRRGGALVQRHYPVIVRNTTALAFKEPVSVCGITTPCKFSVALVMRKIEPVFATGCSVIIKASKRNTPFNTPALATFALAADVPQFLVHEKFQYELIKKIAQRVEGYRLVQDIDEGTTHGPLVNAAAFQKLDAHVKGAPAKGAVLHTAEKFPGVTIEMGVAHDEIFGPLAAIVPFGTETKAVELVNAMECGLAGNCSSWNISRDVRVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPJ2</accession>
    <name>E3QPJ2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cytochrome c oxidase assembly protein COX16, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Cytochrome c oxidase assembly protein cox16, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_07924</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the COX16 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697364">
        <property type="protein sequence ID" value="EFQ32780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096800.1">
        <property type="nucleotide sequence ID" value="XM_008098609.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPJ2"/>
    <dbReference type="STRING" id="645133.E3QPJ2"/>
    <dbReference type="GeneID" id="24413289"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07924"/>
    <dbReference type="eggNOG" id="ENOG502S9GT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131611_2_0_1"/>
    <dbReference type="OrthoDB" id="5516033at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020164">
        <property type="entry name" value="Cyt_c_Oxase_assmbl_COX16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17130:SF14">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX16 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17130">
        <property type="entry name" value="MITOCHONDRIAL OUTER MEMBRANE PROTEIN 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14138">
        <property type="entry name" value="COX16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="31"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ32780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="117" mass="13640" checksum="1970C5B3BC7023D7" modified="2011-01-11" version="1">MAVFSNKKFPSKADTNTFAAKYRAQMAKRPFLMFGLPFVAVMIAGSFVLTPATAIRYEKHDRRVRQVTKDEELNLRRSARKVDMKEEYYRLAAKDIDNWEQKRVQRLKGEHDGIIGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPK0</accession>
    <name>E3QPK0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sodium symporter family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_08049</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697365">
        <property type="protein sequence ID" value="EFQ32905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096925.1">
        <property type="nucleotide sequence ID" value="XM_008098734.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPK0"/>
    <dbReference type="STRING" id="645133.E3QPK0"/>
    <dbReference type="GeneID" id="24413414"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08049"/>
    <dbReference type="eggNOG" id="KOG2348">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010778_2_1_1"/>
    <dbReference type="OrthoDB" id="6132759at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015489">
        <property type="term" value="F:putrescine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015606">
        <property type="term" value="F:spermidine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015204">
        <property type="term" value="F:urea transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11476">
        <property type="entry name" value="SLC5sbd_DUR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="entry name" value="Sodium/glucose cotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031155">
        <property type="entry name" value="DUR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00813">
        <property type="entry name" value="sss"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46154">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46154:SF4">
        <property type="entry name" value="UREA ACTIVE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="134"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="271"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="312"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="345"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="375"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="403"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="432"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="471"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="550"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="581"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="630"/>
            <end position="654"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ32905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="654" mass="70445" checksum="F71C24E9BE238816" modified="2011-01-11" version="1">MDSTPVLNQGWGYGLMIGLGILFAVFMIIITWALKRYNSELQTSEMFTTAGRSLKSGLVASSVLSTWTWAATLLQSTAVAYKYGVSGPVWYASGATVQIILFATLAIELKRRAPNAHTFLEVVKARYGPITHGVYIVFCCFCNILVTAMLLTGGSAVIQNLTGAPVAASVFLFPIGVVVYTLFGGIKATFITDYINGLVILVIIFVFAFTVYSTNELLGSPGRVWEILTELAAKRPLSGNSGGSYLTMRSQGGAIAASPIDALPGYVMGGISWFAVPWLTATTMGLAGLALETYDVWPTYPNRFSPADVDAGLVLPTAAVALLGKGGAVATLILAFMAIMSTYSSELIAVSSICTYDIYKTYFNPSATGKQLMRINYIGMGIFALFMAGFATGLNYVGISMGYLYLMMGVIISSAVLPATLTLLWSGQSWAAATFSPIIGFVLSMTAWLVTTKIMYGELSVTNTGANGPMLAGNLTSLLSPLLFIPLLTFIPPFKPQKYDWQSMLNIRQSDDRDFADGASMDIETAPTVQIQALGGPDEKAKLDKAAKTARWLTVGVTLVLLILWPMPLYGSGYVFGKSFFTGWVVVGITWLFASMIMVVFLPIFESRSTIVRTSQMMLKDLFGIKGRKKPAIDGQSPNLRTPPEVAEKVEPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPU3</accession>
    <name>E3QPU3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ferric reductase NAD binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_08014</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697365">
        <property type="protein sequence ID" value="EFQ32870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096890.1">
        <property type="nucleotide sequence ID" value="XM_008098699.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPU3"/>
    <dbReference type="STRING" id="645133.E3QPU3"/>
    <dbReference type="GeneID" id="24413379"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08014"/>
    <dbReference type="HOGENOM" id="CLU_2038748_0_0_1"/>
    <dbReference type="OrthoDB" id="4494341at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000293">
        <property type="term" value="F:ferric-chelate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015677">
        <property type="term" value="P:copper ion import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF12">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G14340)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179908" description="Ferric reductase NAD binding domain-containing protein" evidence="3">
        <location>
            <begin position="19"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="Ferric reductase NAD binding" evidence="4">
        <location>
            <begin position="44"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ32870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="117" mass="13633" checksum="04D5DE488BD84579" modified="2011-01-11" version="1">MWVRPWLAEILKLPNCSALLTVKLFVTRELIQQRHLPSPDISNSETVISYFYKRPDIMKLLQEEVENQIGAMFVMVCGPGGLSDDARAAVRQCQRSGHEVCFEENCFSWWWRIRGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQA9</accession>
    <name>E3QQA9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Arginosuccinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_08191</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697367">
        <property type="protein sequence ID" value="EFQ33047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097067.1">
        <property type="nucleotide sequence ID" value="XM_008098876.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQA9"/>
    <dbReference type="STRING" id="645133.E3QQA9"/>
    <dbReference type="GeneID" id="24413556"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08191"/>
    <dbReference type="eggNOG" id="KOG1316">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027272_2_1_1"/>
    <dbReference type="OrthoDB" id="2561043at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004056">
        <property type="term" value="F:argininosuccinate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042450">
        <property type="term" value="P:L-arginine biosynthetic process via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01359">
        <property type="entry name" value="Argininosuccinate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.200.10">
        <property type="entry name" value="Fumarase/aspartase (Central domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="entry name" value="Fumarase/aspartase (N-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009049">
        <property type="entry name" value="Argininosuccinate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43814">
        <property type="entry name" value="ARGININOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43814:SF1">
        <property type="entry name" value="ARGININOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00145">
        <property type="entry name" value="ARGSUCLYASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="L-aspartase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumarate lyase N-terminal" evidence="3">
        <location>
            <begin position="7"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00032749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ33047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="371" mass="41692" checksum="DCE7DFFFFAB2F501" modified="2011-01-11" version="1">MEQYNESIHFDKLLHNTNYNNGILTKHEVEEIERGLLEVEKEWGAGEFNTVQGYEGIHTANERWIGEIIGKDIAGKLHTGRSRNEQVACDTRMWLRNELVKLKGHLVSFLKVTDTGAQKEIDYIVPGYTHLQRAQPVRWSHWMLSYAMAFANDLERLLEVIQRVNRNPFGCGALAGNPSNIDHEAISKGLGFEGLLWNSMAGVADRDFVTDTLQWGSVLIQHISRWSEHTHPASLASFLRGKIGQMVGSMMTQKGLPSTYNKDLQESWEPMLDHVKTVSDSIQIAEGALATLGTQPEKMKAALDPFILAANVAEYLAARLIHEQLKAVDERFEEDIAETFNYEKSVEMRAAMGGTSKSSVEQIAVLRVSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRP8</accession>
    <name>E3QRP8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycosyl hydrolase family 92</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_08815</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697371">
        <property type="protein sequence ID" value="EFQ33536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097556.1">
        <property type="nucleotide sequence ID" value="XM_008099365.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRP8"/>
    <dbReference type="STRING" id="645133.E3QRP8"/>
    <dbReference type="GeneID" id="24414180"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08815"/>
    <dbReference type="eggNOG" id="ENOG502QR5Q">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003690_4_1_1"/>
    <dbReference type="OrthoDB" id="449263at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000224">
        <property type="term" value="F:peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006516">
        <property type="term" value="P:glycoprotein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1610.10:FF:000002">
        <property type="entry name" value="Alpha-1,2-mannosidase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.98.10:FF:000010">
        <property type="entry name" value="Alpha-1,2-mannosidase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2080.10:FF:000001">
        <property type="entry name" value="Alpha-1,2-mannosidase subfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1050.60:FF:000002">
        <property type="entry name" value="Glycosyl hydrolase family 92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.60">
        <property type="entry name" value="alpha-1,2-mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1610.10">
        <property type="entry name" value="alpha-1,2-mannosidases domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2080.10">
        <property type="entry name" value="GH92 mannosidase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005887">
        <property type="entry name" value="GH92_a_mannosidase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041371">
        <property type="entry name" value="GH92_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012939">
        <property type="entry name" value="Glyco_hydro_92"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050883">
        <property type="entry name" value="PNGase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01180">
        <property type="entry name" value="aman2_put"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12143">
        <property type="entry name" value="PEPTIDE N-GLYCANASE PNGASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12143:SF23">
        <property type="entry name" value="PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07971">
        <property type="entry name" value="Glyco_hydro_92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17678">
        <property type="entry name" value="Glyco_hydro_92N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178760" evidence="2">
        <location>
            <begin position="19"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 92 N-terminal" evidence="4">
        <location>
            <begin position="24"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 92" evidence="3">
        <location>
            <begin position="272"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="755"/>
            <end position="774"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ33536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="774" mass="84867" checksum="0D7DB976E390CB10" modified="2011-01-11" version="1">MRLLPSVAALTVAAVCQSFDPLAFVDPLIGSRNGGNVFAGATLPYGLAKAVADVDGQKTGGFSTDGSNITGFSILHDSGTGGNPSLGNFPLFPQVCPGDELNNCRFRIGDRATHYDPNKTVAEPGYFSVELTSGVKADMTVSQHAALMRFKFPSGDEHPLVLLDLTDLWASRQNASVTVDTPTGRMLGNGTFLPSFGAGTYALYYCVDFFGAKVFDTGVWVNSRAGNEPKELFITRGFNMFYLQGGGFVRFKELTNNTVTARVGVSFKSSDQACRNAQKEIADPLGRFDSLVKTAKDAWREKLGPVSIKAGGATEDIQKSFWSGLYRNMISPQNYTGENPYWDSGIPYFDSFYCIWDSFRAQHPLLTVIDPAAQTQMVSSMLDIYRHEGWLPDCRMSMCKGWTQGGSNADVVLVDAYVKNLTSIDWNLALEAITKDAENEPPVWSYEGRGGLASWKNLQYITYLDFDPVGFGTNSRSVSRTLEYSYNDYCLATLARGLGEDALHSKYMARSMNWQNLWKADQKSLINGADTNFTGFFQPKYLNGTWGFQDPIACSNLAGFCSLTTNPSETFEASIWQYQFLVPHSTSTLIDLMGGDEGFVSRLKYFHASPLADISNEPVFLTVYLYHYAGRPGLSAERIHQYIPSAFNSSLGGLAGNDDSGAMGAFYAFSAMGLFPVAGQDVYLITPPFFEEVSVKSPTTGKTATVRCVGFDAAYKNIYVQSAKLDGETYNRSWIGHDFFGQGKTLELTLGNKESGWGRSREARPPSYVAVSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QS30</accession>
    <name>E3QS30_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_08597</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the VTA1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697372">
        <property type="protein sequence ID" value="EFQ33668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097688.1">
        <property type="nucleotide sequence ID" value="XM_008099497.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QS30"/>
    <dbReference type="STRING" id="645133.E3QS30"/>
    <dbReference type="GeneID" id="24413962"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08597"/>
    <dbReference type="eggNOG" id="KOG0917">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030378_0_0_1"/>
    <dbReference type="OrthoDB" id="391137at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005771">
        <property type="term" value="C:multivesicular body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032511">
        <property type="term" value="P:late endosome to vacuole transport via multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.420">
        <property type="entry name" value="Immunoglobulin FC, subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.270">
        <property type="entry name" value="Vacuolar protein sorting-associated protein vta1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044538">
        <property type="entry name" value="Vta1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039431">
        <property type="entry name" value="Vta1/CALS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023175">
        <property type="entry name" value="Vta1/CALS_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041212">
        <property type="entry name" value="Vta1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46009">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VTA1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46009:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VTA1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04652">
        <property type="entry name" value="Vta1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18097">
        <property type="entry name" value="Vta1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Vta1/callose synthase N-terminal" evidence="10">
        <location>
            <begin position="13"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="Vta1 C-terminal" evidence="11">
        <location>
            <begin position="362"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="157"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="157"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="239"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="275"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="325"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="345"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF18097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ33668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="396" mass="43104" checksum="195AAD914AD0476D" modified="2011-01-11" version="1">MAEPIPDSLRQADITRFINRANQLRQYKPVITYWCEYWVVNQILAKGLHNVDDESLSYTTNLMDRLEQTKIENAQEEAIIDDAVGQAYVEQFAQDAFERAEKVMKANRVTRQTADTYDAAATFLLLGNIWGAIDEETQKKVKYAKWNAARILKAIKEGKDPNETNPKQEEPKEVLPALDPNDPDVRGLTSPPPKPASVEDDPETEFYKKASTPSESVPPAAPSEPVPTQSSVLDLPSVPTANDLNPPANQNQGYFDPPEDFPPSPLSQKDTNEVAASANAPSAPSPYVASSSGPSFSPENATLPWQPPKIAPPHVAESTPPPAPKQSKPPSAAQQPKAPVVPASHNSWTPSSAPSDDMDLPKAQKHAKWAISALNFEDVPTAVKELRNALAALGAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QS33</accession>
    <name>E3QS33_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_08600</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697372">
        <property type="protein sequence ID" value="EFQ33671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097691.1">
        <property type="nucleotide sequence ID" value="XM_008099500.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QS33"/>
    <dbReference type="STRING" id="645133.E3QS33"/>
    <dbReference type="GeneID" id="24413965"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08600"/>
    <dbReference type="eggNOG" id="ENOG502SMC3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_3_4_1"/>
    <dbReference type="OrthoDB" id="3936451at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF96">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="166"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="28"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="280"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="335"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="365"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ33671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="395" mass="44701" checksum="6E31AB85834A7EF2" modified="2011-01-11" version="1">MAEIENRGPQLVAVGLTLVISAFVATVLRCYVRVFLVKNFGIDDWFMVIATLFFILFVSSALTGVHYGTGRHRVNLSDEDWESAMMYWWYCYLWYCLAMIASKISIGYFLLRITVRKLDIWIIYIVMMLTVCTGVVFFFVTLLQCQPISYFWNQSTQNGHCVPMDVIIALTFLYSAFSVICDFTFAILPIVLIWKLKMNRKTKLALVPVMLMACIASSAVVVRMPFVSDFKNPDFLYATVDIAIWSTVEQGLACTAGSLATLRPLFRLVGYRLGFTSMGPSQLHDSERGDPSANMGGKVKNVSNADSSRQRRGPFSLTTFMAKDDVDSQEIANGESDRSLQHKPSNKRDRGWESTGRRDNESETELTFQASKESTGSDRENITVIQTFSLREDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QS46</accession>
    <name>E3QS46_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GA4 desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08613</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asaB hydroxylase/desaturase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697372">
        <property type="protein sequence ID" value="EFQ33684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097704.1">
        <property type="nucleotide sequence ID" value="XM_008099513.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QS46"/>
    <dbReference type="STRING" id="645133.E3QS46"/>
    <dbReference type="GeneID" id="24413978"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08613"/>
    <dbReference type="eggNOG" id="ENOG502SMV5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042688_2_0_1"/>
    <dbReference type="OrthoDB" id="412788at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044053">
        <property type="entry name" value="AsaB-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041278">
        <property type="entry name" value="CmcJ_NvfI_EfuI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598">
        <property type="entry name" value="BLL6449 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598:SF3">
        <property type="entry name" value="OXIDOREDUCTASE AN1597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ33684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="298" mass="34566" checksum="A6A3867C0B700FE8" modified="2011-01-11" version="1">MPHVTKMPESVWAYVNCHLPPAKGEKYPVQYIATVGFQRAKYDKQLVNVTDSRTCEEDFKLDTHGFQWVESTIQEKQWDGDYRVGLPPQLQNDVQHLLKRHTGATYVHPFAPHVIRRDSYQKIVNIEDDVPDDAMLNMQPPAMFVHVDQSYDGAQIILDRLPEAEMLRGKTHKRWGIINVWQPLKRVNREPLAVCDARSVDESDLVPVTTRIVIGKPPKPMSKDNEQWHMKASPKHKWYYASNMTTDEALLIKCFDSKLDGRARRTPHTAIQTPNDFGPPRESIEIRCLVFWEDQEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSB6</accession>
    <name>E3QSB6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Aminotransferase class V domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_08887</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697373">
        <property type="protein sequence ID" value="EFQ33743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097763.1">
        <property type="nucleotide sequence ID" value="XM_008099572.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSB6"/>
    <dbReference type="STRING" id="645133.E3QSB6"/>
    <dbReference type="GeneID" id="24414252"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08887"/>
    <dbReference type="eggNOG" id="KOG1549">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003433_3_0_1"/>
    <dbReference type="OrthoDB" id="5978656at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43092:SF2">
        <property type="entry name" value="HERCYNYLCYSTEINE SULFOXIDE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43092">
        <property type="entry name" value="L-CYSTEINE DESULFHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="69"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ33743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="463" mass="51256" checksum="5D4FD003B9E5E517" modified="2011-01-11" version="1">MGDLVKETSQLQLGSPPFGKAMLKEFLIDPAYRNMNNGSFGTIPRHIQAVLRSYQDQAEARPDPFIRWTYIDRLNESRQAIAEVLNAPLSCTVFVSNATVGINTVLRNLTWNPDGLDEILYFSTVYGGCGNIIDYVVDISAGLVSSRGITLAYPLEDDEIVALFHETVAKSRAEGKRPKVCLFDVVSSLPGIAFPYQAVTAACRELGIMSVIDGAQGVGMVPLDLAATDPDFFVSNCHKWLHVPRACAVFYVPERNQHLIASTVPTSHGYVARSGVRRHNPFPAADESPFVRAFNFVGTLDNAPYLCVKHAIEWRKSIGGEDKIFEYLWTLAKEGGKKVAAALGTFILDNKSETLTKCAMVNVALPIVTGAADVEAMSVAPDGTVTVPEKEASVVVNWMLKALVNEYLTFVALFWHQGRWYMRVSAQVFLDEKDFEWLGNTMKELCQRVRKQEYKAKAEEGTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSI9</accession>
    <name>E3QSI9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08971</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
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        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697374">
        <property type="protein sequence ID" value="EFQ33827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097847.1">
        <property type="nucleotide sequence ID" value="XM_008099656.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSI9"/>
    <dbReference type="GeneID" id="24414336"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08971"/>
    <dbReference type="eggNOG" id="ENOG502T2G8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_146834_0_0_1"/>
    <dbReference type="OrthoDB" id="4509278at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180886" evidence="1">
        <location>
            <begin position="20"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ33827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="149" mass="15978" checksum="48E6150D55E637E3" modified="2011-01-11" version="1">MKLSTISFLSLTIVVPALSQPLKERDVFQTVHLTFHGGAASYELAIPADGQVHATNNDIAVNIIDAPDYNAISQCTFYTNGEKALASGITSQGLQQVILGPPQPITGVSCFGICVATYGECYNTQVQYVGPCCNGFCAATRCRPWIQPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>E3QT95</accession>
    <name>E3QT95_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_09227</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697376">
        <property type="protein sequence ID" value="EFQ34083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098103.1">
        <property type="nucleotide sequence ID" value="XM_008099912.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QT95"/>
    <dbReference type="GeneID" id="24414592"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09227"/>
    <dbReference type="HOGENOM" id="CLU_2757631_0_0_1"/>
    <dbReference type="OrthoDB" id="5097583at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ34083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="70" mass="7546" checksum="1CF123DD939C1653" modified="2011-01-11" version="1">MAQVTLLLEPDAELAHKDRIEGDASAASIPASADNDNFTTADFEIQVPSFLPDGYGRVFHPQILLHAIIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QU24</accession>
    <name>E3QU24_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_09506</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697379">
        <property type="protein sequence ID" value="EFQ34362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098382.1">
        <property type="nucleotide sequence ID" value="XM_008100191.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QU24"/>
    <dbReference type="STRING" id="645133.E3QU24"/>
    <dbReference type="GeneID" id="24414871"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09506"/>
    <dbReference type="eggNOG" id="ENOG502S4MX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1310015_0_0_1"/>
    <dbReference type="OrthoDB" id="430354at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180952" evidence="2">
        <location>
            <begin position="29"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ34362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="210" mass="23656" checksum="D27F94858B0903E0" modified="2011-01-11" version="1">MPGIKRTRIILALVITCALMLLFRGNEATFQSSQSTKHTIPEQSLEDSSLNSEVSPGHLAAPILDSNLEYHPPLLQQTKLIADAHRLTTADDFIHHFAAVTALKGITQREARATCTWPADTYVDFQFSDTLEWVLEERPVLEIELRRREWHEFIQGQMIPYANVKDRFSGRGLAIVVGNADTVMRVKIILRQLKRLGSTIAVEITIGTPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3QU60</accession>
    <name>E3QU60_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CmcJ catalyzes late reaction in the cephamycin biosynthetic pathway</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09542</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asaB hydroxylase/desaturase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697379">
        <property type="protein sequence ID" value="EFQ34398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098418.1">
        <property type="nucleotide sequence ID" value="XM_008100227.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QU60"/>
    <dbReference type="GeneID" id="24414907"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09542"/>
    <dbReference type="eggNOG" id="ENOG502RYCS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042688_2_0_1"/>
    <dbReference type="OrthoDB" id="412788at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044053">
        <property type="entry name" value="AsaB-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041278">
        <property type="entry name" value="CmcJ_NvfI_EfuI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598">
        <property type="entry name" value="BLL6449 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598:SF3">
        <property type="entry name" value="OXIDOREDUCTASE AN1597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="285" mass="32341" checksum="198C344C3A9B5181" modified="2011-01-11" version="1">MMGQPGRQVKTKIKYFDDPGVPLVPMVIGGPEPGKPQPKIEIPTTITDITGREDEFTLDVQGFHYVKHESQVTNWDDDEEIKRVNYPEMEKLCCKVLAETENMPKPCLVHIMTHIIRRGPKDGEGPQGPAPLYGVHVDQSFAAAEGVAQRWLGDRAEELLKKPRYQIINASMWRPIRPITRDPFAVSDARTIPDSDLVFVPVRFPDHDTEAVEVRPPTNSSHKWYFKDQQQPDDVLFFKQVNSSTKPGVPRRVPHCAFKDTDLPEGAGEPRVSVEVRAFVFYDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QU68</accession>
    <name>E3QU68_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Trafficking protein particle complex subunit 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_09550</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697380">
        <property type="protein sequence ID" value="EFQ34406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098426.1">
        <property type="nucleotide sequence ID" value="XM_008100235.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QU68"/>
    <dbReference type="STRING" id="645133.E3QU68"/>
    <dbReference type="GeneID" id="24414915"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09550"/>
    <dbReference type="eggNOG" id="ENOG502QV3F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003572_1_0_1"/>
    <dbReference type="OrthoDB" id="6278596at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012880">
        <property type="entry name" value="Gryzun"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021773">
        <property type="entry name" value="TPC11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14374">
        <property type="entry name" value="FOIE GRAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14374:SF0">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11817">
        <property type="entry name" value="Foie-gras_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07919">
        <property type="entry name" value="Gryzun"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Trafficking protein particle complex subunit 11" evidence="3">
        <location>
            <begin position="337"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="domain" description="Gryzun putative trafficking through Golgi" evidence="2">
        <location>
            <begin position="632"/>
            <end position="1215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="717"/>
            <end position="738"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ34406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1227" mass="137117" checksum="DBA36134A740073F" modified="2011-01-11" version="1">MDGYPVGSLDHNIPHIVLAGLTSSPTRDLPLNAELRDQAILIRSELPSIQGKDAEALKDYVVRQDGRKQPWNGRDSGKPYKLRVTVAGRSLVLPPRRARLPDGLEAPETPAVLHSPFSPLSPASPLYPDGLMNTDWLQKHEDMVPSVYVSCYTLTSDPTLAMLHDNQLKTDVNTIKAALSRSGYRTRFAVVLMSDGTVPSSMQEFMQDRLDNIRKGVALDTKSFFYFSSHDLSKDLEHAADSMLAAVFLQAIEYYRDLGRHARKKRSRGVAPQPTVPPTSTSQTLTVQDWNVRYDYKTAIFAEYRQEMDAALRSYDQAYEGLLSQDVMDIIPSWSPRWNEARMLADFIAIRSMRCLLWAGQTTAAARRWQIHRERMADFVDRRGRGTNNYGWAAWESRWAIVMANLIERVDVRSLAPSTRTLFLQPEKAAAGERLQPWEMLHHTGYWYRVAAEHLVVRRALARSIPEEDRRSPETTPASALASKAFQYDTYMCPDPHEEFPVHGMGVNHSQLIIDCLMAARSQFQARGQLRLSAELSLECAKEMVNIKAWDDIVALLRPLWEDMSFRTEGWLNITEDLSWVLRAAAAHAGQGELVVAIDWELLNRKFTRRPKWHYDISRSLEGLKLDSKPTVMINDNVISSFISASFIFKTEDGKAGEACQAQLAIKSDAFPDAATVTLKGLRIDFEGSLKTITLDHEAGSTKGTEKGNVTLSRVPLTEKARADAEEGDEGTSGLGGSADLSVKPGHISVYEMAIPLREPGEAHASSVTLVLETDTFTLNYTIAFRNLEAADFWFSPSLSRRRIVRQSAHVIQVQARPPKLEIKLAQPLEQFYANEPMDLLLDVINAEDADAVAKLEVHVFGEQIPPFRVHIENGEEHTAEAGKEEAKLAGLSLGTLATSQTTRINISLDPVQLTTSYDVTLRIFYHLTTDPATLIMQILPAQLTVVNPFEANYDLIPRLHSDPWPSLFDHEGVQDPSVDEAAVQPRGLAQRWCLVCHFASFATDDLELVGMDAEVVACQNNARCTTVSGPEVPEGGLRIPPRQMQEAQFDLVAQKFSLDDKGPASLDVAFVLRWRRVKSPSSAAAAVNTTRMLVPRYIVLGAEPRVLASYSLASPLTGLINLNITIENPSSHFLTFGLSMDPSDEFAFSGSKQTTMHVLPVSRRTITYRLLPLVRGDYIRPTLVVRDKYFQKVLRIIPTEGMKIDKEGLQVWIPPEEGEEGNEGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUB6</accession>
    <name>E3QUB6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_09598</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697380">
        <property type="protein sequence ID" value="EFQ34454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098474.1">
        <property type="nucleotide sequence ID" value="XM_008100283.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUB6"/>
    <dbReference type="STRING" id="645133.E3QUB6"/>
    <dbReference type="GeneID" id="24414963"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09598"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_8_0_1"/>
    <dbReference type="OrthoDB" id="3066029at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF152">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="181"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="271"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="310"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="352"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="381"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="423"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="446"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="57"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ34454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="487" mass="51784" checksum="A415B9523B960BE0" modified="2011-01-11" version="1">MGSPSAETPAHAPPANVPRFMSADPSSGPVPAAPAPPRPAAIDDVVMEMPTWRKWVILSVVCWMALPVIFSGSSILSATNEVAADFDISTHAITTANAGVFIAQAMSALIWLPMSDILGRRTTYLVANTLLSLCSIGSALSNNFACFTAIWIVGGTTGPFFLVAGQTILADIFDPTNRGTAVGFFLGSCVGANTLAPLTGGVIVSFTSWRVIYGVQAGMAFVGLIMAFFFVPKASELAKHRVEEKTPVRSVGELCRAFNPRGVFRLFKYPNVLAANLACGLLGFNQYGLLSSIRRVINPRFNLTSPLISGLFYLAPGAGFLVGSTIGGRVSDYTVKRYIRKRNGLRLPQDRLNSSLPAIFIVLPAGTLIFGWSLQKEVGGVALPVISSFFQGLGLMWSFSGLNTYSAEALPKHRTAVISSKYVVQYIFGASSIGGAVPMIDAIGVGWSFTITALSALSAGVLVLMISKFASRAQNWVEKSNSEDSDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QV79</accession>
    <name>E3QV79_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_09913</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697383">
        <property type="protein sequence ID" value="EFQ34769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098789.1">
        <property type="nucleotide sequence ID" value="XM_008100598.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QV79"/>
    <dbReference type="STRING" id="645133.E3QV79"/>
    <dbReference type="GeneID" id="24415278"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09913"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_8_2_1"/>
    <dbReference type="OrthoDB" id="1933717at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901:SF1">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ34769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="309" mass="34178" checksum="B792198990211FDC" modified="2011-01-11" version="1">MDPFSSVANSSSPFQTGMNFTKTIHRKPYSAILPSRSELSQKGRTILITGGSAGIGFAIAQSFAQAGAKRVIILGRRQNLVDEAVSKLEKEYQGVQFSGFPSDVNDLGDNEKLWKGFEEDGTVIDVLVLNAAKIANDGSILALGRDYVWDSFTMNVRSLLDLSERFYNQKNGEGRQKFLVNISTEAIHNFQKSGPWPAYSASKNAGTLLIQMIAKDTPPENMQIINFHPGLVRTSPFIDAGVPEDRLPFDDVSLSGNYAVWAASEEARFLHGRFVWSKWDVEELKTGDIGKKIRDNDHYLKVGVVGLQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVI8</accession>
    <name>E3QVI8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TAFII28-like protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_10020</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF11 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697385">
        <property type="protein sequence ID" value="EFQ34876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098896.1">
        <property type="nucleotide sequence ID" value="XM_008100705.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVI8"/>
    <dbReference type="STRING" id="645133.E3QVI8"/>
    <dbReference type="GeneID" id="24415385"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10020"/>
    <dbReference type="eggNOG" id="KOG3219">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035243_2_1_1"/>
    <dbReference type="OrthoDB" id="28335at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08048">
        <property type="entry name" value="HFD_TAF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045127">
        <property type="entry name" value="TAF11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006809">
        <property type="entry name" value="TAFII28_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13218:SF8">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13218">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04719">
        <property type="entry name" value="TAFII28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TAFII28-like protein" evidence="7">
        <location>
            <begin position="171"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="244"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="76"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="102"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="133"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="255"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ34876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="322" mass="35141" checksum="594CDC718AB062C8" modified="2011-01-11" version="1">MASPPYSYSPTALSPPYPSSAQLPMSNKKRASDGAPPGSAKRRKASTLSVTSASAHPLRQTSFPPEAGSPFPRSPSADNVSVVSGSQASAPPKKKRGRKPKNQTNVETREQTPSLVGGRAPTTVSGTGAGAEGQEDGANDDDDDNDMRMALVDSTVRTQEQKQEEIRLRAMLVESFDPEQYDRYELWRAAKLTESVVKRVVNATVSQSVPPNVALAVKSVSKLFIGELIERARDVQGEWIKATGEKQSEAPTPPPKDEASQTQAAKEDRRGPLRPDHLREAWRRYKMSGDGGWVGIQGLWHEQQQSGVERFPVRTGGRRVFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVQ4</accession>
    <name>E3QVQ4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Amino acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_10086</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697386">
        <property type="protein sequence ID" value="EFQ34942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098962.1">
        <property type="nucleotide sequence ID" value="XM_008100771.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVQ4"/>
    <dbReference type="STRING" id="645133.E3QVQ4"/>
    <dbReference type="GeneID" id="24415451"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10086"/>
    <dbReference type="eggNOG" id="KOG1286">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007946_12_0_1"/>
    <dbReference type="OrthoDB" id="3900342at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000017">
        <property type="entry name" value="Amino acid permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004840">
        <property type="entry name" value="Amino_acid_permease_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF12">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
        <property type="entry name" value="AMINO_ACID_PERMEASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="99"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="148"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="179"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="297"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="352"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="397"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="426"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="467"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="509"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="9">
        <location>
            <begin position="70"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ34942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="572" mass="62469" checksum="006AC729F1B44F4B" modified="2011-01-11" version="1">MSKEDAQVGVVPPTYDSEKGAHGTVGSNGVPDDFREDDFRTRNGLNLRSFQRRDWGTGTTELDRSMKPRHLQMIAIGGSIGAGFFVGSGSALTKGGPGSVLICFLIAGVMIFNVVYALGELAVLYPVSGGFYTYSIRFLDPSWGFAMGWNYVFQWVIVLPLELTVASFTVQYWNKDISVAVWITVFWVFIIIVNVFGTLGFAEEEFFSSAFKLVATVVFMVVGLVLICGGGPEGGKYDEYWGNRLWSDPGAFQNGFRGFCSVFVTAAFSFSGTELVGLAAAESSNPAKALPGAIKQVFWRITLFYILGLTFVGLLVSSTDERLLNSENPYADGVSPFVLAPLDAHLYGYDSFMNVVILVSVVSIGVSCVYGGSRTLTALAQQGYAPKIFTYIDRSGRPLPSVALNLAFGGLAYVRMASSGGVVFDWLLSLSGLAALFTWGSIVAAHIRFRAAWKAQGHTIDELPFQAVGGVAGSWLGLFLVFICLIAQLFVAICPPSGGFASAEDFFKAYLAGPVVLVFWLCGYLWKRKGFLKLSQIDLDTGRREVDWDEIHAYRAKVATWPKWRQFLNTVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QX47</accession>
    <name>E3QX47_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_10579</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the Mrp/NBP35 ATP-binding proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697393">
        <property type="protein sequence ID" value="EFQ35435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099455.1">
        <property type="nucleotide sequence ID" value="XM_008101264.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QX47"/>
    <dbReference type="STRING" id="645133.E3QX47"/>
    <dbReference type="GeneID" id="24415944"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10579"/>
    <dbReference type="eggNOG" id="KOG3022">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024839_0_2_1"/>
    <dbReference type="OrthoDB" id="1741334at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140663">
        <property type="term" value="F:ATP-dependent FeS chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02037">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001278">
        <property type="entry name" value="Iron-sulfur cluster carrier protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02040">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019591">
        <property type="entry name" value="Mrp/NBP35_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044304">
        <property type="entry name" value="NUBPL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42961">
        <property type="entry name" value="IRON-SULFUR PROTEIN NUBPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42961:SF2">
        <property type="entry name" value="IRON-SULFUR PROTEIN NUBPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ35435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="297" mass="32433" checksum="9E9C08373A8A757D" modified="2011-01-11" version="1">MRPTLFRPFQPTIRVLGHENPLGLPKSGTPPNWPRKPVQRKIRGVEKVVAVSSAKGGVGKSTVAANLSLAFARLGYRAGILDTDIFGPSIPTLFNLSGEPRLSQGNQLIPMTNYGVKTMSMGYLVPEDDAVVWRGPMVMKAIQQLLHEVDWGGLDILVLDLPPGTGDTQLTITQQVILDGSIIVTTPHTLAVKDAVKGVNMFNKVNVNILGLVQNMSLFSCPHCHGDTYVFGSNERVERMCRDHKIDFLGDVPLHPSIGDDADLGKPTVVAEPMSERAEIFLKMARDIAPKIDLRMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QX90</accession>
    <name>E3QX90_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Impact N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_10622</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IMPACT family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697393">
        <property type="protein sequence ID" value="EFQ35478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099498.1">
        <property type="nucleotide sequence ID" value="XM_008101307.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QX90"/>
    <dbReference type="STRING" id="645133.E3QX90"/>
    <dbReference type="GeneID" id="24415987"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10622"/>
    <dbReference type="eggNOG" id="KOG3299">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031573_0_0_1"/>
    <dbReference type="OrthoDB" id="416496at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140469">
        <property type="term" value="P:GCN2-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006446">
        <property type="term" value="P:regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.30">
        <property type="entry name" value="Impact, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023582">
        <property type="entry name" value="Impact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001498">
        <property type="entry name" value="Impact_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036956">
        <property type="entry name" value="Impact_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020569">
        <property type="entry name" value="UPF0029_Impact_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301:SF4">
        <property type="entry name" value="IMPACT N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301">
        <property type="entry name" value="IMPACT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01205">
        <property type="entry name" value="Impact_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00910">
        <property type="entry name" value="UPF0029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Impact N-terminal" evidence="3">
        <location>
            <begin position="245"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="55"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="205"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="425"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="229"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ35478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="538" mass="57778" checksum="FB2B8CD1F4B2083B" modified="2011-01-11" version="1">MMAAMGKAKALQAVGLQSIQQISHAPFDVVERALGDAKTAKSLITACKAHSKQSASKRAGDLLSAPSSKRTSKQHIGIDSEVAGRSAEEQEDALTLPVITNEEDIAEASVYTNRAPLMLAFVLELLRHTMPLQPLSSRLSLAQAVVNANATTKAVSIGLAKTSGEDDSWGDGQPKVSIMGRRIAVLKRGDYRLEGDEADVPECSGGTLRAAPQAALGPSGATLQGHGNAASTPSPWSTSRQITFKSSTFVARVTSAGDDGQASALIRSLLSTEPHLKTAAHNAWGYRVQKQGQGRKSREIHEVCEDDGETGCGEFILRLMREAGVDDVVVVLSRWFGGELLGPDRWRLMRNVTTEALSQRLRIHQNEVECQGVALWALDFQKKNHAPGGSGSALNAGDWSHAVVGASIYRPETAREYLLKAFDPDSSDDSTKGNGGEGGMAGKVPRTKGKKLSRSEAEAERLRHLGLLLGALRLLLESWSSLTPLELDRRAFSWYTAIRPDVDPGIAGWGAKGWLKLSDILRLRRNSEGKEVTVSSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXT1</accession>
    <name>E3QXT1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_10776</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697397">
        <property type="protein sequence ID" value="EFQ35632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099652.1">
        <property type="nucleotide sequence ID" value="XM_008101461.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXT1"/>
    <dbReference type="STRING" id="645133.E3QXT1"/>
    <dbReference type="GeneID" id="24416141"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10776"/>
    <dbReference type="eggNOG" id="KOG4177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_278974_0_0_1"/>
    <dbReference type="OrthoDB" id="823504at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24173">
        <property type="entry name" value="ANKYRIN REPEAT CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24173:SF74">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="590"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="720"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="788"/>
            <end position="820"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ35632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1131" mass="126839" checksum="0B9176FA71E0ECDE" modified="2011-01-11" version="1">MTDVDVEENISKFIDVEAETIFKAKKLKQSPEEICSWIKGKSGNFFFFAKFFLQNFVATVEDADACKYSMTTILLPCLELLRQYYGYELLPMFQNIDNQNYLLSILQIVINSKSSTSTEEITDAIACFHDDSRLRRLDIRSVLQQKCPRLIHVDDNSELHITHQSFCSHFMCYINKEQQHANMAFLCLKYLSQPIFGRDCNDSPTELPRHHPFYNYAARWWEDHFRLSDREGTKLLSQLGYFITSPCYNAWSSHRSWNIAINQWARKTPMYNAIMSNPWIPPAITLTKANAGHLTSELQATYGMVEPKSRSWKDNSSILVAKFMHRFDVFHGLNRLLENAHPEPDFSVRDAAGHTPLMAAAMVPDGLPDMIKFFLRKTQDVNERSFVHGDPALLLLCRFLDLRHDFLFGDMLSLFLAAGADPNISGLDGNTCLLEACERNSLLLDTLDDINQLDGAGFAAIHILTAPDYIEWLPHLLKRPDVDLDLLSNGLEDDRKRALRRTPLGFAIFHDNFKAVEMLLEAGANPCRCPGTTDDTPVYMAVKVARTTNYKNSKHDKSKFDKNGNVDILELLLSYQSPINTLLNHKSKEYAKSPLRLAVHLGDQNMVELLLRHGADPTLEEAYGLLGPLDAAIVHGDEDITIILVKTLLDNELPPSINYLPEDNNHADHVLSAASELKPALVQLLLDYGADMKENNVDICKVLVEHEPGLVNCQFEEGLVCEAPIHLAAREGHKDIVRYLLDVGATPDLLSYHWHETPFWSACYNGKLEIPQLLYDKSPKTLDTTSYDGSTPLIVVCDTGNLQLVRFLLEKGADAKARRSTGESCVHSAVSKDNGAAHKIVDLLIQHGLGIDDVVSAIGFTVLGEACRVGDAQTVWMLLEKGADPSKGQKPPGNTSGAWRSALHVAAIGGQPKIVEILLQSPQLFSFVENVDYYGDNVLHLGSPGSSAKAYEITDKIYRACQRLESETGIDHFPAMLAVETRGLHTLIDIAMGSLHKRLSDEALAKTDEIIRQYVEELTTGDQRTVFHPKHLMSDLSFLLLQRDGYDQQAVRLLQTLTIDVSIKELKDRFIDTAAWTICCEVCDGPGGPNEDDDDDEKEVICFCRFCRLILHFMLSDTSSSDAEPGVHTCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QY13</accession>
    <name>E3QY13_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">amidase</fullName>
            <ecNumber evidence="3">3.5.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_10906</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a monocarboxylic acid amide + H2O = a monocarboxylate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:12020"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:35757"/>
            <dbReference type="ChEBI" id="CHEBI:83628"/>
            <dbReference type="EC" id="3.5.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amidase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.4" evidence="3"/>
    <dbReference type="EMBL" id="GG697399">
        <property type="protein sequence ID" value="EFQ35751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099771.1">
        <property type="nucleotide sequence ID" value="XM_008101580.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QY13"/>
    <dbReference type="STRING" id="645133.E3QY13"/>
    <dbReference type="GeneID" id="24416271"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10906"/>
    <dbReference type="eggNOG" id="KOG1212">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009600_9_2_1"/>
    <dbReference type="OrthoDB" id="6428749at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004040">
        <property type="term" value="F:amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072">
        <property type="entry name" value="AMIDASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072:SF5">
        <property type="entry name" value="GENERAL AMIDASE-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001221">
        <property type="entry name" value="Amidase_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="7">
        <location>
            <begin position="82"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="5">
        <location>
            <position position="237"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="234"/>
            <end position="237"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ35751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="538" mass="59194" checksum="AD0D78A580010147" modified="2011-01-11" version="1">MASEWQELIQKKRAVRDALIPGEWRLPTDITNKVSQESSHNAFELLNEAALLSDREIDITENYTATSLTAKIASGELSSYDVAAAFCKRAALVHQLTNSLTEIFFDKALERARWLDEYYAKEGKTVGPLHGLPVTLKDMIHVKGEYSTMGFVGHLKHPAADEHAVIAQMLEAAGAVFYCKTNVPQTLFVCESYNNVFGRTLNPYKLCLTPGGSSSGEAAQLGLRGSIMGVGSDIAGSVRVPALFTGVYGFRPTVNRLPFAKQADLAPKGWQGVQPTLGPMARTAQDLTLFMKTIIQAQPWRYDATAFAVPWHDAPRKEKLTIGVWSQDPDFPVYPPIKRAMASAVDKLRAAGHTIKVIAAPPTMKAMKIAMRWFALDQVNLPFKFLEAGGESPIADLESMNPGNFLDPGYVPDLHENIRISADIHDYREEWAKIWRDADLDVLLCPASRGPAVPHGEFGPLMYTILWNLLDFPSSVIPFGHVDKAVDSTDGCKRAPTWISYDASVVDGAPTGFQLVGWRFQDEQTLMATEVVADALKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QY20</accession>
    <name>E3QY20_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_10913</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697399">
        <property type="protein sequence ID" value="EFQ35758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099778.1">
        <property type="nucleotide sequence ID" value="XM_008101587.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QY20"/>
    <dbReference type="STRING" id="645133.E3QY20"/>
    <dbReference type="GeneID" id="24416278"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10913"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_0_1_1"/>
    <dbReference type="OrthoDB" id="5410178at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF157">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="276"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="314"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="353"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="379"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="418"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="449"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="47"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ35758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="483" mass="52207" checksum="7D9A5392A2EF15E6" modified="2011-01-11" version="1">MAVVAISEVQGPRQNAIELKTGSMSCDELSWATDCRGHPRSWGRARKTYDTCWVIFLEFYTTTISTAGTPVAAHVYRDLGVSPVLATFLFVSTYLVGQAIGGVFLPPWSESFGRKKPYIVSTALYSISCVLVAACPTIPGIVVGRVVGGFLSAIPAIVAAGSIEDLWDTHDRVWWVFWWAMVGNIGLLAGGVVSDLIISCAHWTWVFYTPAIVNACMAALLFTIKESRPSVVLARTLSDNERTGSSQVSGTKPGNTPSREKLDIVRPLRFLFTEPIVFLVSVISAIAFGLIYLFTEVLPIIYVSMGLDNGWKNTPFLALGLGIIASGLTRIYDSRTLAARSAKGLPITPESKLAGVIIGAPLLASGLWCFAWTIPPDVLLHWAVPTAALVPIGYAVNEYDYVLAGYLTDCYETYAASAFAALGLTRALLCATFPLLGSVLFHSVNPNKASSIFAVLATVLCIVPPLLLRYGRRLRNRSPFIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYC0</accession>
    <name>E3QYC0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ABC1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_11049</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697402">
        <property type="protein sequence ID" value="EFQ35858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099878.1">
        <property type="nucleotide sequence ID" value="XM_008101687.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYC0"/>
    <dbReference type="STRING" id="645133.E3QYC0"/>
    <dbReference type="GeneID" id="24416414"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11049"/>
    <dbReference type="eggNOG" id="KOG1236">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006533_6_0_1"/>
    <dbReference type="OrthoDB" id="1290869at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13971">
        <property type="entry name" value="ADCK2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044095">
        <property type="entry name" value="ADCK2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052402">
        <property type="entry name" value="ADCK_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45890:SF1">
        <property type="entry name" value="AARF DOMAIN CONTAINING KINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45890">
        <property type="entry name" value="AARF DOMAIN CONTAINING KINASE 2 (PREDICTED)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="3">
        <location>
            <begin position="206"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="3">
        <location>
            <begin position="298"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ35858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="689" mass="78122" checksum="BE1868B34B7A3384" modified="2011-01-11" version="1">MRLAFVLGRFCPRPGFRAPSNGTHFYSTFRSAFRTSQTRPLPWRATRYTRYTLRAGGAGVGALGTAAFFELSEKDNGGTDQTGEKRMLEVSRAEINKKVADDDSGISRVWHTLTITLDLYVWEPLCTGVRFLHLLVIFVPVIFAVPAIWLGRRRPDRDNERTGTLWWYGFLVQSMEWAGPAFIKLGQWAASRTDIFPTEMCEIMSKLHSNAPAHSMYDTKRIVSAAFDGRNFDDIFDEFDEKPLGVGAIAQVYRAKLKPGLAAPGDKDIDETPKPLRHKVAKNVEAALKSTPKRVPSSYVAVKVLHPRVERTVRRDLRIMHFFASALNLIPTIEWLSLPDEVAQFGEMMKLQLDLRIEAANLAKFRKNFKDRTTAWFPYPYTEFTTRSVLVEEFAQGIPLADFLENGGGVFQEDIASEGLDAFLRMLLIDNFVHADLHPGNIMVRFYQSHEPELKFRRNTGKGHPEEQDDVTEQVLARLRPYRHRKNPAAWAAELQKIDDEGFRPQLIFIDTGLVTELNETNRTNFLDLFRAVAEFDGYKAGNLMCERCRQPDAVLDKEVFALKMQHLVLGVKSRTLALGNIKIGDILQDVLGMVRRHHVRLEGDFVNVVISILLLEGIGRSLHPDMDLLSSSLPILRQLSAQSGTEMAKHGDFSMLVVWAGLETRRFLQASIEDVERCVKYDLLAPNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZB1</accession>
    <name>E3QZB1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AP complex subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_11344</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the adaptor complexes large subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697414">
        <property type="protein sequence ID" value="EFQ36199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100219.1">
        <property type="nucleotide sequence ID" value="XM_008102028.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZB1"/>
    <dbReference type="STRING" id="645133.E3QZB1"/>
    <dbReference type="GeneID" id="24416708"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11344"/>
    <dbReference type="eggNOG" id="KOG1060">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006320_3_2_1"/>
    <dbReference type="OrthoDB" id="10254310at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030117">
        <property type="term" value="C:membrane coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030276">
        <property type="term" value="F:clathrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026739">
        <property type="entry name" value="AP_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016342">
        <property type="entry name" value="AP_complex_bsu_1_2_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11134">
        <property type="entry name" value="ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002291">
        <property type="entry name" value="AP_complex_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="8">
        <location>
            <begin position="37"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="658"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="720"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="659"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="733"/>
            <end position="778"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR002291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ36199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="778" mass="86001" checksum="51290D2E0408CC3F" modified="2011-01-11" version="1">MESIARISSLLESARELTLDAASATRSSRSTGRPLDRTQIKKLLDSRNDREVLDGLRRVLSMMYRGQKTLPFFSSVVKNVASPNIEIKKLVYIYLIHHAEQEPDLALLSINTIQKSLSDTNPQVRALALKTMSGIRVPVISQIVSLAIKKGVADMSPYVRRAAALSIPKCYRLDPTQLPQLLEYLTALIGDKQYFVAGAAVSAFLEVCPDRIDMIHPHYRALVKKVVDMDEWSQLATLRMMTYYTRKCFPRRTHSVKGQEKTADLGDFYAENAQQGGEEQQVIAVDPDLALLLNGIKPLLQSRNSAVVIAVTRCYVEIGTPEYVKIAIGPLVALLRGPQDIQQVALYNIVSVCLTRPTDFVKYASHFLVRATDPTQVWELKLEILTLIFPHAPPHIKSLILHELEHFSGSTNKALVREAVRAIGRCAQTDSSTAPRCLRLLLGQITSLDGTLAAESLTVIRHLIQQDPQGHVCTVVRLAKNLDSATDPHARATIIWLVGEFSGLEGEDNIAADVLRILLKDFANEAEVAKGQILLLAAKVYLHHVNRQSEDKGEDEAAVPNQDDHPVAKLWDYALLLVRYDTSYDLRDRARMYRALLSVPQLATLMLLAPKPAPQAPSPSEIRKGFMLGSSTLVLAGGGGIHGLRGYEGLPDWVAEGSEPDRRLRETETPSAYGGEKSVPASQMLDNAVKAAPTKTNGLGAAAVGAGVGVKTLDDWLAEEEIEEQQEAFKMDGEDEEESEDETDEGDDDDEEEEEEEEEEEEEDDDDDEEESSDDNSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZD7</accession>
    <name>E3QZD7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tat pathway signal sequence</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_11370</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697415">
        <property type="protein sequence ID" value="EFQ36225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100245.1">
        <property type="nucleotide sequence ID" value="XM_008102054.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZD7"/>
    <dbReference type="GeneID" id="24416734"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11370"/>
    <dbReference type="eggNOG" id="ENOG502S30I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022771_0_0_1"/>
    <dbReference type="OrthoDB" id="5596992at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031428">
        <property type="term" value="C:box C/D methylation guide snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990259">
        <property type="term" value="F:histone H2AQ104 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008649">
        <property type="term" value="F:rRNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000494">
        <property type="term" value="P:box C/D sno(s)RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018812">
        <property type="entry name" value="SAK_HAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10335:SF23">
        <property type="entry name" value="OB FOLD-CONTAINING PROTEIN, NUCLEIC ACID BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10335">
        <property type="entry name" value="RRNA 2-O-METHYLTRANSFERASE FIBRILLARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10307">
        <property type="entry name" value="HAD_SAK_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Swiss Army Knife RNA repair protein HAD" evidence="2">
        <location>
            <begin position="55"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="432"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="469"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="511"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="554"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="599"/>
            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ36225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="619" mass="67550" checksum="6976D1918ACEFC61" modified="2011-01-11" version="1">MTSAHANGSAKAAYSSSSATTTALSRWSIATKQLPAVGNIKSLHIYDFDNTLFKTPLPNPALWSGPTIGVLSSQDVICNGGWWHDSRILAATGEGADTEEKRAWDGWWNEKIVELVKLSIKQKDALCVLLTGRSERGFGELIKRMVQSKRLEFDMIGLKPAVSPTNQHFSSTMHFKQLFLTAVMETYKNADEIRIYEDRPKHVKGFRDFMTEYNRKQNMNATRTRGPITAEVVQVADLSTTLDPVVEVAEVQHMINLHNEEIAKQPTDVRPNRLMVKKTVYFTGYMISKEDTARLMKLAQIPPGMPEQELKFHANNILICPRPCPASILEKVGGMGSKMKWEVTGTACFENSIWAASLRPVPTTAKFHTDNPAPLVVLALRKGARPVDAGKIQNWQPVPADKAMTFETTVGEKMILRIEPEDPREDEYESLFANKSSKRKHDGGDYSRDHHRHGNNPYNGRNERRDFHSGGGGGGGGGGGGGGGGGGGRGQGRGGHRGGGGRGGRGHRGNGKGGRGGRGMHGYRSLDDVEPRNQQGGYGQPVEYDDSSYPSLPAQPQQQQQQQQQGGFYGQQQQYQPPNNAWQQQGPPPNAPTGPSGRPMGGGGNYGGGGGGSDLQNYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZF6</accession>
    <name>E3QZF6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">galacturonan 1,4-alpha-galacturonidase</fullName>
            <ecNumber evidence="12">3.2.1.67</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Galacturan 1,4-alpha-galacturonidase C</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Poly(1,4-alpha-D-galacturonide)galacturonohydrolase C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">GLRG_11389</name>
    </gene>
    <organism evidence="19">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Specific in hydrolyzing the terminal glycosidic bond of polygalacturonic acid and oligogalacturonates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>[(1-&gt;4)-alpha-D-galacturonosyl](n) + H2O = alpha-D-galacturonate + [(1-&gt;4)-alpha-D-galacturonosyl](n-1)</text>
            <dbReference type="Rhea" id="RHEA:14117"/>
            <dbReference type="Rhea" id="RHEA-COMP:14570"/>
            <dbReference type="Rhea" id="RHEA-COMP:14572"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58658"/>
            <dbReference type="ChEBI" id="CHEBI:140523"/>
            <dbReference type="EC" id="3.2.1.67"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the glycosyl hydrolase 28 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.67" evidence="12"/>
    <dbReference type="EMBL" id="GG697415">
        <property type="protein sequence ID" value="EFQ36244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100264.1">
        <property type="nucleotide sequence ID" value="XM_008102073.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZF6"/>
    <dbReference type="STRING" id="645133.E3QZF6"/>
    <dbReference type="GeneID" id="24416753"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11389"/>
    <dbReference type="eggNOG" id="ENOG502SI66">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016031_1_2_1"/>
    <dbReference type="OrthoDB" id="187139at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047911">
        <property type="term" value="F:galacturan 1,4-alpha-galacturonidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004650">
        <property type="term" value="F:polygalacturonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000743">
        <property type="entry name" value="Glyco_hydro_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31736">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31736:SF11">
        <property type="entry name" value="EXOPOLYGALACTURONASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00295">
        <property type="entry name" value="Glyco_hydro_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 16" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 16 18" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 17" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180973" description="galacturonan 1,4-alpha-galacturonidase" evidence="17">
        <location>
            <begin position="21"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00038933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00041474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00042262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU361169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EFQ36244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="432" mass="46523" checksum="38C3C77753DDBCB8" modified="2011-01-11" version="1">MHHRSLLPLVLFCIAASAAACLPRRCIVATSRETTSDAAAIADAFARCASDAEIIFPAGAEYRAYEPVVATKLSNVVITVDGNLSLPRDIPALQKLVEVKGGRLTWFRLGGTNVQWIGSSKPDAGWIKSYGQAWWDLNRPGEAGTPNRPHLMQFNVTNGVMRNVKSMKPIGWSFSIEGSNISISDAVVDARSEDGGGFPFNTDGFGVGATDVTITNSRILNGDDAVAVTDGARNVLFKQATIGFQTHGMSVGSLGSDASSSADVQNIRFEDVTVQGGLYAARFKSWIGGKGLARNITWSNIRVDNVTFPIFVTQNYQDQASPGCNRSNSSSVMMEDFTWEHFSGNINTYNPGDGSCTTNPCWYNSGLVNPTHTEAVIIGCSDGKSCRGFQTRNIRINPQSRTVPKVICMNAAPDLNPNLGFECANGTYMISH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZT4</accession>
    <name>E3QZT4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ubiquitin fusion degradation protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_11517</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UFD1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697421">
        <property type="protein sequence ID" value="EFQ36372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100392.1">
        <property type="nucleotide sequence ID" value="XM_008102201.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZT4"/>
    <dbReference type="STRING" id="645133.E3QZT4"/>
    <dbReference type="GeneID" id="24416881"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11517"/>
    <dbReference type="eggNOG" id="KOG1816">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012913_0_0_1"/>
    <dbReference type="OrthoDB" id="193703at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034098">
        <property type="term" value="C:VCP-NPL4-UFD1 AAA ATPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.50">
        <property type="entry name" value="Ubiquitin fusion degradation protein UFD1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.130.10">
        <property type="entry name" value="Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain (AZUL)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032353">
        <property type="entry name" value="AZUL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042556">
        <property type="entry name" value="AZUL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056012">
        <property type="entry name" value="DUF7590"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004854">
        <property type="entry name" value="Ufd1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042299">
        <property type="entry name" value="Ufd1-like_Nn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055417">
        <property type="entry name" value="UFD1_N1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055418">
        <property type="entry name" value="UFD1_N2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12555:SF15">
        <property type="entry name" value="FUSION DEGRADATION PROTEIN (UFD1), PUTATIVE (AFU_ORTHOLOGUE AFUA_4G04640)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12555">
        <property type="entry name" value="UBIQUITIN FUSION DEGRADATON PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16558">
        <property type="entry name" value="AZUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24503">
        <property type="entry name" value="DUF7590"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03152">
        <property type="entry name" value="UFD1_N1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24842">
        <property type="entry name" value="UFD1_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23580">
        <property type="entry name" value="Znf_XAF1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin fusion degradation protein UFD1 N-terminal subdomain 1" evidence="4">
        <location>
            <begin position="81"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin fusion degradation protein UFD1 N-terminal subdomain 2" evidence="7">
        <location>
            <begin position="164"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7590" evidence="6">
        <location>
            <begin position="264"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-protein ligase E3A N-terminal zinc-binding" evidence="5">
        <location>
            <begin position="647"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF24503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF24842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ36372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="758" mass="84160" checksum="2BB57397E4506AEC" modified="2011-01-11" version="1">MEESQPELKWSAPFAVLPPSQSAPRDLRGDKILLPPSALEQLLAASPRPPAPANSTFTSYDPFNPYARHHQTQYHHSDSSQQLPNPLMFRLVNQNNGNIVYAGIREFSADDGEIALAPYLMEALGILPTDFGSETSSGEPIDATDDSTKHTQPRVTVHANQLPKGTYVRLRPLEAGYDPDDWKSLLERQLRESYTTLTKGTVLSVRGVKGEDFKFLVDKFLPEGDGICVVDTDLEVDIEALNEEQARETMRQIMAKAQPGTANGSSKGSELDVWKPAEGQVLPGEYVDYELPSWDRTRPLTIELSELSVPDSLDLFISPKSARQRAQPRDFEHIFSNFAPSQDGRKAITIRPTNIELENAEQLLIAVHGYPLAGGSEDSVPVYFRLRAKAEGEAELHDATVDLVNDETRPIDEEQCKNCLQWVPKRTLVLHQNFCLRNNILCTRCRHVFKKGSLEWEAHWHCEHDDAHGDSSASKAKHDYVRHTERQCPSCEFTAPSLVELALHRTSVCPGKLILCQFCHLEVPQEGDPLNPSAETILSGLTAHELADGARTTDCHLCQKIVRMRDMTAHMKHHELDKVSRSKPAICRNANCGRTLHGVGSAGSVGAGTAMGQGPGNDLGLCSLCFGPLYVSMHDPEGKALRRRIERRYLGQLMTGCGKKWCGNEWCRSGRANLGLESKGTSAQAALPIVKPLVQSIPQVQEPIYFCVDEASQRRRKLAEMLAGEGVWDFEWCLAACEAATGDLDKAREWLVNWAPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3R007</accession>
    <name>E3R007_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">VPS9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_11596</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0507 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697425">
        <property type="protein sequence ID" value="EFQ36451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100471.1">
        <property type="nucleotide sequence ID" value="XM_008102280.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3R007"/>
    <dbReference type="GeneID" id="24416960"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11596"/>
    <dbReference type="eggNOG" id="ENOG502R3ZQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002294_0_0_1"/>
    <dbReference type="OrthoDB" id="7464126at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030133">
        <property type="term" value="C:transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097422">
        <property type="term" value="C:tubular endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045022">
        <property type="term" value="P:early endosome to late endosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06093">
        <property type="entry name" value="PX_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.20:FF:000443">
        <property type="entry name" value="Putative vps9 domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.80">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051248">
        <property type="entry name" value="UPF0507/Ank_repeat_27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003123">
        <property type="entry name" value="VPS9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037191">
        <property type="entry name" value="VPS9_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24170">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24170:SF1">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G09870)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13857">
        <property type="entry name" value="Ank_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02204">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00167">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109993">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51205">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VPS9" evidence="4">
        <location>
            <begin position="349"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="539"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="596"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1284"/>
            <end position="1329"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1190"/>
            <end position="1221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="619"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1286"/>
            <end position="1299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ36451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1329" mass="148235" checksum="6BD8CDB105848F51" modified="2011-01-11" version="1">MQPLNPFLAAFFRSSLPSQCTPVHHHILLVPATDVLFTCREIESGSTFHELITSEEFLASHVLRIPASNTAAAAGGKDGAQNLRELRGKAKQYQTINGRTVVIKDIHVYSNKGFKSLAQAQLLNDSTWYPDMLEPRQWLIYYISRPLMGVWEEIKIEPAVLIEGMARRQALEQSRSSAAEGTEGAMVPRKKDIKSFHDLLTHFPVIARQMQPGLEKLFREFSTVFERPLPPPPSAFRIPDPAPDGPITTAMRNARSNSMSTAERPNGVSNGLPVTENFYAEDDEDVMRASLETAVTAAIDLFQGVDKQQLSMLGATTDLTGPLVERLIERYVSENVHYLLFPRLSALKRPYDLELEAKIRQMEYIDLSQLGITIEGGTRGKHDLTIQLGLAVEEFKKMANAPSPQEMLDLLLSTMKLVTHLTNSSQARATSSLEKPTITINADTLVSLLLFVVIRAQVRHLHARLIYIRHFIFIDDVDNGEMGYALSTFEAVLAYLVLDSAGLRRASRRNKALWDAACNGSLDDLKKIMEPDSNAIIDDDLYDSPDSSRRPSRSWSYTNGSTSKRSSAALTFSDRFSSGSGLSHVFPFQAEDNGSDLEFPLPPVPPPPRKVKRVAMDTRSMSSGSEISYHSRATSNGTVESVLEGDITIDRLSQTHNLFGESILMMAVQNERPDLLRYLLTLDEYYPPSVVLDDINNEDTTLFSAAVQLGHAELINVVLDFVMASAPKERLLEYFAQQDIWGRSCAHYLFHAPFLISRIGKLIPWRQKDKNGQTPLFALCRSYDHVHYREMVDAGLDAATEAQGDELPLHIDDHVDAKGNTLLHIVNDAQLAIRVLQQCDVDVNATNEKKFTPLMVASKYGRLDMVRTLFVDTRVDVAARELRSLTAVELAKDDDIRNKIDDLALFSMRPGADARITGVVRAFFVEDATIRLVLKSAAPADHLSYTVTTSRRNLSDFENLGNLLALENPASWIPAVAGVRSPFQIPSKPSRAVLRDIQTRVDWFLKIMLNHPTFATHEMLWEFFLVPDIQLGMMEQRSKLKAETRAEKVREEYAPVRDVREVEQFVDHAREMVRSVNYSTKSVARRVNSISVVASDLHDASALLYRAVSTLPFLPPAYITALDSYVRTIAPMQSNPYGIFHSTFLASQSTIQALLSALSRPPAQIAQISAARKSAERSYNSLTRSTRWPLGLLDDTRQRLNEEREEKARQSQEQVDDLGRELRYSQQVVAGELAGWQDLHEKMGRRAIKDFAKGMVVQERLRLDGMMRALRRLREGKAELERASASLANVSGPSGMSQSTRERTGTDAGEGASGASSRVGSEVANGAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0C7</accession>
    <name>E3R0C7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_11724</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697439">
        <property type="protein sequence ID" value="EFQ36565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100585.1">
        <property type="nucleotide sequence ID" value="XM_008102394.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0C7"/>
    <dbReference type="GeneID" id="24417088"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11724"/>
    <dbReference type="HOGENOM" id="CLU_1970391_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ36565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="127" mass="14565" checksum="E4ADFC704F0E8DD0" modified="2011-01-11" version="1">MILTYYPTSDLEAEFSYIGHHRCRGIFHPAIYEGGEPTPAAERFHEMSKGCKLPLWVLHPGIYTTCGRLSGWRVGFSQVIVPYILGLIQRKRQMHTRLRLPDDTITFPYYTGDGDCNKIKTEAAKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0E7</accession>
    <name>E3R0E7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_11718</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697440">
        <property type="protein sequence ID" value="EFQ36585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100605.1">
        <property type="nucleotide sequence ID" value="XM_008102414.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0E7"/>
    <dbReference type="STRING" id="645133.E3R0E7"/>
    <dbReference type="GeneID" id="24417082"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11718"/>
    <dbReference type="eggNOG" id="ENOG502S07J">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051199_2_0_1"/>
    <dbReference type="OrthoDB" id="18530at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40368">
        <property type="entry name" value="YALI0F14399P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40368:SF1">
        <property type="entry name" value="YALI0F14399P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005673550" evidence="2">
        <location>
            <begin position="23"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ36585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="297" mass="32834" checksum="72C3F710C8E03DE9" modified="2011-01-11" version="1">MASFAQVLLGLAVCCMVQFVAAHPEDGLPSYHYGAPIHVECMNRSSETGEHIENSNHEIEWIPFPVCEETNKPLEFRYGHEGELNCTIPMVSDPFFHLLEFFIHNDAPLACRLPARPAPTIEVVGEKPYQQEHIPLVFALAGTLQRSHLHVSTHMNVLLHSMPKHHLRPHDSGVLDSGTAYSTSPLSHMDGIYTQRLVIGDPLPLRLSVRWFPTPNLPKSEGHVEWQGMGGHIYASTIFYIATSFMAGVLVAATYFFGVVLPKRLRGRGLGGATPLGYGLNGVGNGWGYSKTAKRMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3R111</accession>
    <name>E3R111_COLGM</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">GLRG_11948</name>
    </gene>
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        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697544">
        <property type="protein sequence ID" value="EFQ36799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100819.1">
        <property type="nucleotide sequence ID" value="XM_008102628.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R111"/>
    <dbReference type="GeneID" id="24417311"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11948"/>
    <dbReference type="eggNOG" id="ENOG502T866">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_735679_0_0_1"/>
    <dbReference type="OrthoDB" id="4851843at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180135" evidence="1">
        <location>
            <begin position="20"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="316" mass="29490" checksum="0DF162BAF584458E" modified="2011-01-11" version="1">MKGSIFATALTAFSAGAFARPGSYDSPGKTTAGSPFGDGSNGGGIGLIPENLAGGGSGDVLSAGLFGSNNKGISPTTALLGGKGGKSGISGAFDNALPTELLGGNNKGSANPTEAYSGSGGLGGKGGISGAFDNALPTELLGGNNKGSANPTEAYSGSGGLGGKGGISGAFDNALPTELLGGNNKGSANPTEAYSGSGGLGGKGGISGAFDNALPTELLGGNNKGSANPTEAYSGSGGLGGLGGSGSALDNVLPTGILGGSSEGISLPTVLPVAGGGAKAFPNIGGGNTPSGFKTYVRVTSTRGSDSGSTAPTGAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q1X8</accession>
    <name>E3Q1X8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00223</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089099.1">
        <property type="nucleotide sequence ID" value="XM_008090908.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q1X8"/>
    <dbReference type="GeneID" id="24405588"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00223"/>
    <dbReference type="eggNOG" id="ENOG502QQIE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012066_2_0_1"/>
    <dbReference type="OrthoDB" id="415532at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025340">
        <property type="entry name" value="DUF4246"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049192">
        <property type="entry name" value="DUF4246_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049207">
        <property type="entry name" value="DUF4246_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119:SF1">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119">
        <property type="entry name" value="IFI3P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14033">
        <property type="entry name" value="DUF4246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21666">
        <property type="entry name" value="DUF4246_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4246" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4246" evidence="1">
        <location>
            <begin position="49"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ25079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="533" mass="61268" checksum="F0DC74221C30F3E2" modified="2011-01-11" version="1">MLWFIEKITNKPDWHVKVFNNDIVSKWKTEVMTVDWKAVHLEHAHFNNAVFAWCLAELREKAALYEATGLVPVFDATTAVIKADNAISLEVKEELRKGVSVLEDVQEHAKDWHPGSDGKVLDLVHPSLYPLVYDSVKACGTGQNIPVPEKKPDESRFAQGLWSYKFHWLPCEVDIHDDNPAITSYINNLHPQHHAGLYVTIEKVIKKALPLWNVIYRWHIDFEVLNVPCTEARRECKAGRTNYCTRENRPLEPGEDERNEDVYDRESSQLNKAWFDRTHPVKRPSVPNYSPMLLQPKDVNLERGFLDDADRIQVIVKLANNQLTPEKPTYDGGSWHIESQINEHICATALYYYDNDNVTESRLAFCTNANKEDLMEVLSYGQDDISSIERTFKISGRGNITQELGSVLTREDRLLAFPNVYEHCVAPFELMDKTKAGHRKILALFLVDPAVPIISTANVPPQQRDWWKEGCMPDGHFGPLPAEVADMTFDDLDFLISLERAKKIREELMAERTAKSPWDSSDRRMDTWSFCEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2J1</accession>
    <name>E3Q2J1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00436</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089312.1">
        <property type="nucleotide sequence ID" value="XM_008091121.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2J1"/>
    <dbReference type="STRING" id="645133.E3Q2J1"/>
    <dbReference type="GeneID" id="24405801"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00436"/>
    <dbReference type="eggNOG" id="ENOG502S0CM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015358_0_0_1"/>
    <dbReference type="OrthoDB" id="4925544at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="748"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="66"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="83"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ25292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="807" mass="89068" checksum="E1CB25E303F2247E" modified="2011-01-11" version="1">MNPTEAHDDAGLGESTYELINTDDESQDGRATEAESTSSFDYTRIDDVHSLAGTEQTEDMTNQSDTDSDSEDDENAAQDRSRASSIQYAEQSLLNPSSRVATPPLGVERSFESSRLATPLVHSIEFDETQGPLQLKQVAVKHTIHSFTEEKSGSIAKALSFPDKSKRLFAAVRQTMASDFLATREPLRILYTGSHGAKHDIIYKISSAFTASASVDECGITEDDGIYNVVPISSRGSAKVPEVELMKTSQYQIKVENCTAAREIVYEGDRFPSETVYSITIDGDRTFHSAFAPSGSIIEPAWTLPHVAIFYVTENDDETAQKTRAAAWQFMQRHAVPCIFISNAETFHNPTVNWNNMINQHAIHLCVESSDRASPSVKLPIDLTSFLNIDARQMNRNLAYLTGLYDAAGEPAKCGKSDGYVRAMKMMRNIRQRTIDATEDLDLWNIGQTLMLSLGVIAAALLCNHFMAGSPAPAMSAVTSTTPLAQVTPATSASVSTSTITINLTSTTTIRVPQAKASPGNTAVAPFAELADFLADRFPESQKGYVCSAEKSGRNEILIKIPSGTKTSWLAKDSITIDVLKGERSIKTRFSSIDEGIVIEIPKSEAYGLLTIAVNTTRKPKVNETFLVDFGKTTLEQCLGYGKLFADRVIDAASSAARQAEEGGVHLTSWKDSVLADVREMSARFTTEAAHTASVVKESCQNLQNLRESRKLQDFKDQMDIFVTKAQISSRLLVLKVLQKTEEHGTYLDKAKKYMEKLRLQASEASKRRLDKERKELRARRKRERLEARCQTGTGFSRWTQQCRQQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3E7</accession>
    <name>E3Q3E7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">WD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_00693</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089569.1">
        <property type="nucleotide sequence ID" value="XM_008091378.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3E7"/>
    <dbReference type="STRING" id="645133.E3Q3E7"/>
    <dbReference type="GeneID" id="24406058"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00693"/>
    <dbReference type="eggNOG" id="KOG1963">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005417_0_1_1"/>
    <dbReference type="OrthoDB" id="4096at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000234">
        <property type="term" value="P:positive regulation of rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045943">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd23952">
        <property type="entry name" value="Utp17_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057644">
        <property type="entry name" value="Beta-prop_WDR75_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053826">
        <property type="entry name" value="WDR75"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44215">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 75"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44215:SF1">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 75"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23869">
        <property type="entry name" value="Beta-prop_WDR75_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23769">
        <property type="entry name" value="Beta-prop_WDR75_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="358"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="WD repeat-containing protein 75 second beta-propeller" evidence="10">
        <location>
            <begin position="544"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="894"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF23769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ25549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="960" mass="105329" checksum="83104BA743EB5428" modified="2011-01-11" version="1">MAGPSTPISREDAKKRKRELNERDGQAKRLRQRGKQSPGKTLKNGQTDAGDLRDDALNVLSQLQKNLTDDQIESELVKLGNTEAQEAGWQVSMPMGGRMADIDPIFAENEKYLILTYNTSLQIYSVAESLLIRKIALPVVQYTYSEKVSAPTIVATRQSQVKPDFLWVACSDGRVWRVNWKKGTTVYDEFRTQSQTALDMSVVAIEGAKNKTEVIYVSEGKKQSRSEIVAYFGPDFTNPTSEVLFTSKQVDQGIHLLHSSADGKTIVGATREGLVVGTVAPEVSKTDVSLECEFFTFDTADIVCSLDIRVKNNKDGLVLDLIAGGARGAIYFYNDILRKLQNINAPKSKKDSLQGRKYHWHRRAVHSLKWSKDGHYMISGGSENVLVLWQMDTGKMNHLPHLSGSIENIAVSPTGASYALHLDDNSAMVLSTSEMKPSTYISGIQSAARFTSTPKDLLVKRVWSVSDEVRHPVPAALNPAKPSRLYVCTGTGQQAMLAGELQSAPLLQSFDMESFRSISKQALARTQPTDVNITSKGNPISEPRITHVAFSQDGHWLATVDDWQPPKRDLEKVAPEAREQFVRERREVYLKFWSATAGEENFALSSRINSPHVTSRPETVLALAADHATNRFATLGDDGMARIWQSRTRQQDGLTSKDTTGEALHSWSCSLAVGLGSNVGADALALAGETTSERSGSLCFSEDGSTLFVAFGSSNDGAVYVIDTKSGEIRLTLENLWKGHIRRLQVLSPYIITLSDDLRVYDVVADELQYGIQLPSGRNAAAVKEFSHLAIDRKSRTFAVVVPGGQASQLAVFKPEEPELLCVRRIPHRITSLVSAGNSSGFVAVDDAAQLWTIAEATDPASVVLSRPLEDMQLDGEPVSSDAILDDTIEDEDMASDNEQEEHVANGDEMDLDDDDAQPAVINRQKLAELFDAAPAFAMPSVEDMFYKVTGLLATKPLGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3X7</accession>
    <name>E3Q3X7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NmrA-like family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_00873</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089749.1">
        <property type="nucleotide sequence ID" value="XM_008091558.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3X7"/>
    <dbReference type="STRING" id="645133.E3Q3X7"/>
    <dbReference type="GeneID" id="24406238"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00873"/>
    <dbReference type="eggNOG" id="ENOG502SJUJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_8_6_1"/>
    <dbReference type="OrthoDB" id="3358371at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051164">
        <property type="entry name" value="NmrA-like_oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748">
        <property type="entry name" value="NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748:SF26">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="1"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ25729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="327" mass="35768" checksum="820FC2F781EBFC5B" modified="2011-01-11" version="1">MSKLITILGITGVQGGSVADAYLQTPRWRIRGITRNPGSEAARAWASKGVEVVQADLDDVESLKRAFVGADVIFGVTDFWTIIKDPASSAKKRPGQELVEYCYEVELQQGKNIADAAATVPGLHRYVFSSMANAAKESRGKYSKLYHMDSKAEAAEYAQTLPALRNKSSQVQAPVYFNLLWQWGLPTTPKKQADGTWRLSGIGPGDKGIPLGHVRKDLGPCVKAVAEAEPNVNLFAIGEYVSWTECLRIFCETQGLKYGGYDELSFDQLCDLLPGGIGHEFGLNMLFAFEFGYAGTDPALITPDKLGVRMTSFLDYCKETDFSAILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q418</accession>
    <name>E3Q418_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Fungal specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_00474</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089350.1">
        <property type="nucleotide sequence ID" value="XM_008091159.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q418"/>
    <dbReference type="STRING" id="645133.E3Q418"/>
    <dbReference type="GeneID" id="24405839"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00474"/>
    <dbReference type="eggNOG" id="ENOG502RZ2S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006926_1_1_1"/>
    <dbReference type="OrthoDB" id="3990906at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051711">
        <property type="entry name" value="Stress_Response_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47540">
        <property type="entry name" value="THIAMINE REPRESSIBLE GENES REGULATORY PROTEIN THI5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47540:SF6">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="7">
        <location>
            <begin position="251"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="31"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="31"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ25330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="627" mass="69609" checksum="A36980890972F43D" modified="2011-01-11" version="1">MSTLSTRLYIDGLLDEIQRLKSQVARHTSCSTSAQDHVVTQGSRAGNRAMTPLSGRGNDGEEAAASAALEVKPWFINANVFRTPILIGEVADPAFSTRIRQVISDPFSLQPRHMLRVNYAPDTELMSLVKSDISWPTPSRSRFLVEVALKYVSHRYHVVRRSLVMENLEQSIHNPSWGHLMLRSKLWALFAIGELYSTRSIPSEKEFPGMAYFAKASRILGVLDERPGTDSIEIILLLSFYSLALNRRYSAFVMSGTAMRMAIVMGLHLNIPESQLRDPDLREHRKRLFWTTYIFDRVWASKLGHPTAIQDSDIGIDLPSEPVASQTFGDDFGDTAYHIASLRLAALVTKTVRSIYGQRNQGDATLSTRVQQALKDLRTWVEDLPSHLRIDNAGTEPTCISLHLSFNQCAILATRPILLHILRTKVAAWPSESPVTETQVPASAVTLSEACIRCARHSVRLLTDSWIDGSFATFDYFYTQYLFSALTVLAASSLLDGPDARGDRDAFEESARFLSQLGDAGNFAAQEYCHHADVLRAEIERFHAKRMGPPEGGPGVGLGLGTVPPQSGPAIPAHATAGMALTEPSLEELLAQPVLDLQFLEASFYDDLQGLYWPDFSTENWDTWAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q481</accession>
    <name>E3Q481_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00537</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089413.1">
        <property type="nucleotide sequence ID" value="XM_008091222.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q481"/>
    <dbReference type="STRING" id="645133.E3Q481"/>
    <dbReference type="GeneID" id="24405902"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00537"/>
    <dbReference type="eggNOG" id="ENOG502SWYU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1796323_0_0_1"/>
    <dbReference type="OrthoDB" id="2986332at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180036" evidence="1">
        <location>
            <begin position="18"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="144" mass="15135" checksum="3DAAA8639D7345EE" modified="2011-01-11" version="1">MLLKNFVLLLSAELAAAAAFGPPRDYSPEVINLEATELQRRAACAAAGVVNGQCGRFYRGTGCNDQIGANGPGRCSGTCWSSSDAIASIRAVGDGTYGTNCHLYYDSNCQSQIGETGNAITGGGKCYTPSDGRTGHSYLCWYRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5B7</accession>
    <name>E3Q5B7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_01028</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089904.1">
        <property type="nucleotide sequence ID" value="XM_008091713.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5B7"/>
    <dbReference type="GeneID" id="24406393"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01028"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_13_1"/>
    <dbReference type="OrthoDB" id="6133115at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000117">
        <property type="entry name" value="MFS hexose transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF31">
        <property type="entry name" value="HEXOSE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="201"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="292"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="330"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="360"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="393"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="429"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="459"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="43"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="515"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ25884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="543" mass="61003" checksum="DD6C8A88CCAC3ED9" modified="2011-01-11" version="1">MMFSKLKDSKPNQEATIHAQEEAPDFEHVTWYQDPGLRKLYWHAFILCVGSASTGYDGMFFNSVQNFDSWKDYFDHPTDHLLGLLAALYQIGSLGSIPIVPYFTDHFGRRLPIVIGGVITIAGALLQGCCQNLGGFMGGRVLLGFGNSFSQMASPMLLTEICHPQHRARLTTVYNCLWNVGSLTVAWVCFGTNFMNSHWSWRIPAILQALPSVVQIVGIYWVPESPRYLIANDRLDEALEILAKYHANGNAEHPTVKFEYREIRDTIRLERLAKEHSSYLDFFRSPGNRYRLMILISLGIFSQWSGNAIISNYTNILYDNAGVTDSTAKLGLSAGSSMVSLIVSITFALMVDKFGRRPTFLTSTGGMFGTFVFWTLTCALYEEYGSPGANHAMIFFIWVFNVAYAIAWSGLLIGYAVEILPYQLRAKGLMILNIAIQSALTLNNYANPVALDFFEGETWKLYLIYTCWIFLELCFVYFKYVETKGPTLEELVKVIDGPDANVVQLNIQQIEKETQMNATRDSETAEGANSADHSIDNKGTLRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5N6</accession>
    <name>E3Q5N6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Flavin containing amine oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_01671</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the flavin monoamine oxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008092356.1"/>
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    <dbReference type="AlphaFoldDB" id="E3Q5N6"/>
    <dbReference type="STRING" id="645133.E3Q5N6"/>
    <dbReference type="GeneID" id="24407036"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01671"/>
    <dbReference type="eggNOG" id="KOG0029">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004498_1_2_1"/>
    <dbReference type="OrthoDB" id="9982100at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00084">
        <property type="entry name" value="HMG-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Lysine-specific histone demethylase 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000249">
        <property type="entry name" value="Lysine-specific histone demethylase Aof2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050281">
        <property type="entry name" value="Flavin_monoamine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007526">
        <property type="entry name" value="SWIRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742">
        <property type="entry name" value="FLAVIN MONOAMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742:SF386">
        <property type="entry name" value="LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04433">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50934">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SWIRM" evidence="6">
        <location>
            <begin position="150"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="HMG box" evidence="5">
        <location>
            <begin position="899"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="899"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="996"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="38"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="87"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ26527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1034" mass="114650" checksum="EB09B99D4E2DBA54" modified="2011-01-11" version="1">MTASPPSRISSEAVSEIAPEIVVWTEDMDLDDTSQDEAGPSSAPASNPDSPMAEEAESETLHIQSHDTPHESFESPLTNLSDHEQSELSSVPSSLSSKATTPVDLEGHKDFSIPSTETPLVREAVRRSFDVKPKSSIPSNLSNYEYARQCIEAAESSRLNPYALHQEEYQMFRHHISHVQVTTYLNIRNGILRLWYNNPRVAVTRNEAVGCANVRWFDVASVCYDWLARRGYINFGCVEFPGTSDRAEQATGTDHVPGRKRIVVIGAGMSGLGCARHLDGLLRQYSDRYRALGKPLPEIIVLEGRGRVGGRVYSREFKSKPTLPLPDFDGERFTAEMGGMIITGFERGNPMNVLVRAQLCLPYRALRSETTIYDSNGKPVDYVRDQLVENLYNDCLDRVSEYKFKSQPSKLIEGNRDLINEARDAVSDGHRTIGQAEEATAALPHAPPVSQQNVPERVNLVPVSSDKLTGRVHTQPGTPGILKASEKARMMGWTLKNGAANDANIDLNEAAGLPTATLGSVMDEAVVQYRNIVDLTAQDHRLINWHVANLEYSNATNLHNLSLGGWDIDAGNEWEGKHTMIVGGYQSVPRGLMHCPTPLDVRPRAAVNKIKYDTQENGRASVYCEDGTTIEADYVVSTIPLGVLKQGNVEFDPPLPKWKTDVISRIGYGVLNKLVLVYDHPFWDTERHIFGVLRDAPNRHSLNQSDYKSSRGRLFQWFNVTQTTGLPCLVALMAGDAGFDTEHNSNDNLIAEATEVLRSVFGPAVPYPVESVVTRWASDKFARGSYSSAGPDMQPDDYDAMSRPIGNLFFAGEHTIGTHPATVHGAYLSGLRAASEVVDSMLGPVDIPTPLVLPKESVSNKRKDMEGPKDPEQTLLEAYDLAAWEHIKSKIGERPSPPGKLVVNAYLLYSRAFFGIARKKCEDERAGRKKPAPNEVRVMTSKMWKATTPEERKPFEDQALEQKAAYAKAVTAYNEKLAQWDKDYVEILAAFRREHPYNPLNGEGSGSQRENSAQKHRRTKQVSYAESDGSDVEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q621</accession>
    <name>E3Q621_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sphingolipid long chain base-responsive protein LSP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_01413</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090289.1">
        <property type="nucleotide sequence ID" value="XM_008092098.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q621"/>
    <dbReference type="STRING" id="645133.E3Q621"/>
    <dbReference type="GeneID" id="24406778"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01413"/>
    <dbReference type="eggNOG" id="ENOG502RCV0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046464_2_1_1"/>
    <dbReference type="OrthoDB" id="5599269at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036286">
        <property type="term" value="C:eisosome filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070941">
        <property type="term" value="P:eisosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000005">
        <property type="entry name" value="Sphingolipid long chain base-responsive pil1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028245">
        <property type="entry name" value="PIL1/LSP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31962:SF4">
        <property type="entry name" value="PRIMARY COMPONENT OF EISOSOMES (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31962">
        <property type="entry name" value="SPHINGOLIPID LONG CHAIN BASE-RESPONSIVE PROTEIN PIL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13805">
        <property type="entry name" value="Pil1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="287"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="189"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="52"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="319"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ26269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="349" mass="38498" checksum="390A702DF39E7AD0" modified="2011-01-11" version="1">MLRFFARSSEKCDGSENADLNTTGCGSPMMSSITTPSTNRSLSIRSNHRRNGSQNTSTKRTGFSFNSLRGNVQPELSRKLYRIIKSENNLITAHETAGRERISIATQLSEWGEQTNDAAVSDVSDKVGVILSELGEQEDQYAHSLDDARGVLKHIRNTEKSVQPSRDGKDKIADDIAKLKMKEPQSAKLVVLEQELVRAEAENLVAEAQLTNITRQKLKEAYEAEFAATIERAEKQIILAKHGRRLLQLLDDTPVVPGDMRPAYHHAQQARQILNDAEDDLRDWRPEQDDYAVDPSDSVSNARGKQSVGHDDDAHIVASSATRNKATQESDAGSAVSDGTRQGEVLAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q633</accession>
    <name>E3Q633_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Short-chain dehydrogenase/reductase 3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Retinal short-chain dehydrogenase/reductase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_01425</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the reduction of all-trans-retinal to all-trans-retinol in the presence of NADPH.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090301.1">
        <property type="nucleotide sequence ID" value="XM_008092110.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q633"/>
    <dbReference type="STRING" id="645133.E3Q633"/>
    <dbReference type="GeneID" id="24406790"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01425"/>
    <dbReference type="eggNOG" id="KOG1201">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_5_0_1"/>
    <dbReference type="OrthoDB" id="10253736at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052650">
        <property type="term" value="F:all-trans-retinol dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05339">
        <property type="entry name" value="17beta-HSDXI-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000131">
        <property type="entry name" value="Short-chain dehydrogenase/reductase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24322">
        <property type="entry name" value="PKSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24322:SF736">
        <property type="entry name" value="RETINOL DEHYDROGENASE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="360"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="360"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="381"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00059620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00068717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00082544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ26281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="390" mass="43096" checksum="F86FE9E25A55652F" modified="2011-01-11" version="1">MPMHQGFLPREGLTADPIFRLIARTALNPALMLPLLLLARYTKKGGDLAILHPTAFSRVKLLAYCALTRWASSWLSRRVLNGWSSDQYDWRREIVLVTGGAGGIGGHIVQFLAERGITVVVLDIQNLTFTAGSNVHYFKCDITSTEKLAVVANEIRAKVGHPTVLINNAGVARGKTVLDSTEHDVRFTFDVNTLSHYWTTKEFLPNMVKNNHGMIVTVASFASFLCVPNMVDYGSSKAASMAFHDGLSAELKTRYNAPRVRTVLVNQGYTKTPLFQGYQQGFGYILPELEPETVAEAIVKQVLSGESGNVVLPAYGNAMVALRAFPYWYQSMMGAQSVRLMANFSGRQVIKDVKGFYDEKVNGSEGEQERPEESTILVEQEPIPESSSPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q672</accession>
    <name>E3Q672_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_01464</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090340.1">
        <property type="nucleotide sequence ID" value="XM_008092149.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q672"/>
    <dbReference type="STRING" id="645133.E3Q672"/>
    <dbReference type="GeneID" id="24406829"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01464"/>
    <dbReference type="eggNOG" id="ENOG502T2EZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015357_0_0_1"/>
    <dbReference type="OrthoDB" id="5428925at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="275"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="446"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="412"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="115"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="173"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="458"/>
            <end position="480"/>
        </location>
    </feature>
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        <location>
            <begin position="484"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="514"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ26320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="701" mass="75712" checksum="F67BAF04DEF6B94C" modified="2011-01-11" version="1">MGLFKSPNQSPAPGALPRSQTGQSIRGKISGPIPIPSPSDDEFPMRNPGTGIATTLAAAADMKEQQLLPPQAEPRAGSIVSVAQPEVTPAPRTDSVVAPARSARSRSASPPASATHGNSPQSQRRTNISSNLRYSAVSASSGQTGESRDRPQRKKSTLRGALGKLFGRKKKTGSQGSADSQRISTYNNASNQHKSQDLSALSRVTEAEPKRSVSLPITEYDRALRSHSIGPHDITVIESARNSISVDLSVLGHRRAATATTSQIYSAPFRGREGEFSGLSPRPASSHVRGSRLFADNDDPEAIGRAITSDVGQKRRSRSLSGLQSTEIRADLRRRSDEIRYWRESYVPTFIASPTSSNPPDHEHQFAGVGSEGMPDSPVEQGQQQVHTPPQPFSFGNLTHMNVMAGMKITQAASIETRIDTLEERMHRMEDVVTRLCNSVPGFQVYANPPRRPAPSIPDSNPSSQTTTTTAVNPVLQQVLRQDAYASSYGSSAHSKEPRTSFGEAPTHVGSLQFPASMNRPMSNSTLRGVTSLPAISHLETSRATGTFTADHYTTLLTLLETERASRKALESQVKKLTRRVNILSGPVGPGRISLQMEPPPTAKSFGSVSAFDQDSSDDDAFSRNRRFLAEDSGVGTGLGDDDSYSEVFATPKEEYPYGYGAFGEELHDEIEDPQRKKAARTLSLSQMTLSKKTSNTAVRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6K9</accession>
    <name>E3Q6K9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_01601</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090477.1">
        <property type="nucleotide sequence ID" value="XM_008092286.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6K9"/>
    <dbReference type="GeneID" id="24406966"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01601"/>
    <dbReference type="HOGENOM" id="CLU_2426884_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="91" mass="9624" checksum="63E57763C2FCC8A5" modified="2011-01-11" version="1">MVGTPSSSSRKSLNWSSGGGRQTHSWKSFREVRGGAEFDMTKCSGATRKEEALGDVGSPSTASKRMLSLLPVKVFPQTPSKASEAAFTVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q729</accession>
    <name>E3Q729_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_02487</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090687.1">
        <property type="nucleotide sequence ID" value="XM_008092496.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q729"/>
    <dbReference type="STRING" id="645133.E3Q729"/>
    <dbReference type="GeneID" id="24407852"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02487"/>
    <dbReference type="eggNOG" id="ENOG502S4E9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011385_1_0_1"/>
    <dbReference type="OrthoDB" id="5392646at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048401">
        <property type="entry name" value="SLS1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032741">
        <property type="entry name" value="Sls1_KH-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048748">
        <property type="entry name" value="SLS1_KH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048400">
        <property type="entry name" value="SLS1_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14611">
        <property type="entry name" value="KH_SLS1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20777">
        <property type="entry name" value="KH_SLS1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20778">
        <property type="entry name" value="SLS1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20776">
        <property type="entry name" value="SLS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SLS1 N-terminal" evidence="3">
        <location>
            <begin position="158"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="SLS1 first KH" evidence="2">
        <location>
            <begin position="271"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="SLS1 second KH" evidence="4">
        <location>
            <begin position="341"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="SLS1 C-terminal" evidence="5">
        <location>
            <begin position="432"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="759"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="760"/>
            <end position="778"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF20778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ26667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="786" mass="87560" checksum="A98349F6910BE69D" modified="2011-01-11" version="1">MSIRKRRLYSADSAWDRIETASDGEKDSSNSIKDTRSDGVSPKDEPPQAQPVASSPSAASGLNGPSSETEPATQDKPLIREPFFVRDHRGRREHRRLGKRSVYLQSQELDVNMLGEKARAIVMRETSGNSRALRELPVEEPLAPDFDLKASLEAEAKDLTMEEALANVDGVRPTEPIVSQSEFDGLLEVLLNGFTVAQLRAYLARENAKARRTPVGEKVLQYDWIQDENPWTPFLKPEVAGSPKERLALTLMIEAWRLRIREMVDGTGFYSAKIKERIHALLARDRQRLDAIRDAYLDEGEDIQFTNQRLRITSTKAKTETILKKLDEAAQLVVTKHVHAPWLSNYDVRSTLLHHLGQLTNTFITFSTKTHTLRISWFNDGVVEENDAGEQLDNVVQRLLYTALQPEDASVSLQYDPKNDNGKLIPESSGQEKLSWKDRLTQWSRYVAPVGRVSPAESGFPLEASDVFSHPIQRLVQDSDATWSKRYTSTVASFGKILHRKQDGFNLAVAAKAKNHVFSPTSPHPTSLNALEEALTTIPTQPMQTTLVLGFRRHPSLYAMKGLPHLLKLRLVVPWELPEGPLSWDACEKDLVAVLDQTFTDVAYPSEPVDMRLSQSWLSVMSPAALDASPFCEYAKNAKLDLAAGRLRPPPEIELSGLPSTEGAGVFGGAATYVFSGLEIRRSLGVRYQGHKVHYTSVEAGLHGGRRSELVFEALPTDDDAPDEVGKAYANRYLALAHDLVTGKVVKWVGERDVAREFENVDTGDVDPAAAEEEGEEAETQKKDDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7H0</accession>
    <name>E3Q7H0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02628</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090828.1">
        <property type="nucleotide sequence ID" value="XM_008092637.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7H0"/>
    <dbReference type="GeneID" id="24407993"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02628"/>
    <dbReference type="eggNOG" id="ENOG502R6AF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_959808_0_0_1"/>
    <dbReference type="OrthoDB" id="4809652at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="2"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="314" mass="36371" checksum="8C44E9C60527EA6F" modified="2011-01-11" version="1">MFIHYKKLPPEIRAAIWKLAFGGGRIVSTEALRHTPPAAALANRESWAEYTKLEFMVTPGGGRVYFDPEIDIVVYSRLTDYPPCQGEPRLQNDIHREYRGHVAKTSGSGRMQPPLLPQPIANPHPGLRTAMMVTETSYSEGHTLMTWDPLTRTLKDLIENHKRDPIMKLPKILIKIFPNLRTLWRAGSCPWSCQYARDPSTAGWHLKFVQFRYYSASQRVMIRDMPKPARREFWRIQRHVTQSRIEQPSAYRVVAAIDIIRERDIAPADMTDGWRIVRTFEEETAGGQDKLQYDLLPDRLWWMILGGEIDRYIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7Q8</accession>
    <name>E3Q7Q8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_02091</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ26920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090940.1">
        <property type="nucleotide sequence ID" value="XM_008092749.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7Q8"/>
    <dbReference type="STRING" id="645133.E3Q7Q8"/>
    <dbReference type="GeneID" id="24407456"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02091"/>
    <dbReference type="eggNOG" id="KOG0158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_11_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009403">
        <property type="term" value="P:toxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11058">
        <property type="entry name" value="CYP60B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000047">
        <property type="entry name" value="Cytochrome P450 monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF230">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="97"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="438"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ26920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="494" mass="56374" checksum="86B82D6E804AE05F" modified="2011-01-11" version="1">MLSSVQLAVALPTFLLALVIIRLLWNVVYNVYFHPLRDYPGPKLFAATHIPFSRMIISGKSHKRLAELHKQHGPFVRLGPNTIDCADPRAFKDLMGHSKGGGGVENGKDPINTRNRPRSIINSGREDHARIRRVLSHGFSAQSMVEQQPLIQKQIDMLVQRLHEHCENGSKPLNMVAWYNYTTFDIIGDLALGEPFGCLERSDYHPWVASIFNAIHATVYRNQFGRYWITQSFARRLIPKRLKEGLEFHDQTSHEKIQRRMALGESRPDFVQSMMMKEGSLAMSELEVEETANTLIIAGSETTASVLSGVTFFLTTHPDAMAKLVEEVRTSFSSEKEIDVLSVQKLRYMLAVLDESMRLYPVVPIGLTRIVKPGGDYICGRFVPGGTRVLVSQWPMYHNEKHFAQPESFIPERWLGDARFTDDYKSALQPFSVGPRNCIGRNLAMSEMRVILARVIWNFDMEIAEDSRNWTEQELFGLWKKGPLNVYLTPRKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8J9</accession>
    <name>E3Q8J9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alpha beta hydrolase fold protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02041</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ26870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090890.1">
        <property type="nucleotide sequence ID" value="XM_008092699.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8J9"/>
    <dbReference type="STRING" id="645133.E3Q8J9"/>
    <dbReference type="GeneID" id="24407406"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02041"/>
    <dbReference type="eggNOG" id="ENOG502RISQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_780769_0_0_1"/>
    <dbReference type="OrthoDB" id="5343383at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="328"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="335"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="359" mass="40512" checksum="A687A6C0D421AC1B" modified="2011-01-11" version="1">MPLLEQSPLNCTFNPDDVVAGLTQYYLTLTRMAYIPASYVDFPPPGGWTDVELDVGALRALRRSETVINLLRHLPYPRPMHDGPRPGPWNVAPRSKAVRYLRHMGSFSQWSDRGDAGLHELAALPMGDTPAAPMDLPPDVVCLTFGERQTRNGARPYWWIVDCSRGILTPFQEGTYGIAKVPRNKPWRTVQSYPVSDFFARLVPDLGLNLLPVPPTEDLDAEVLGPSSGSLGREVAHIYMAHGWSNADFRHDECITALQAWRRQVQERERQKMAQDVDDADDEDFEMEDSDDDDDDNDNDNDMDQGEAGELLAEAVADMEVDDLSAEAAALRADMSPEERRRFDRRENQLPPFEWIDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8Q6</accession>
    <name>E3Q8Q6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chitin-binding type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_01915</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091440.1">
        <property type="nucleotide sequence ID" value="XM_008093249.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8Q6"/>
    <dbReference type="STRING" id="645133.E3Q8Q6"/>
    <dbReference type="GeneID" id="24407280"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01915"/>
    <dbReference type="eggNOG" id="ENOG502STNY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_670868_0_0_1"/>
    <dbReference type="OrthoDB" id="4846743at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178296" description="Chitin-binding type-1 domain-containing protein" evidence="2">
        <location>
            <begin position="31"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ27420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="383" mass="40008" checksum="0083D8B3209A0BFC" modified="2011-01-11" version="1">MKSIHLGVTSSRASLWLAVVSSLFLPRISANSCQPYIWDSLSSMRIASVDDPVDISPTEGEPLPVVNPGEINCRFWTNTPEEVDYYTCSRLARRYLMPVDQVFFLKPELDKDCSNIQPQTEYCVEGLRTAPPASATRASVMATISNTAPTERAAAGETAVAQRAGVARLTPSAASSPARVAAVTSGNRTSSQPAGTKWTKGGTCGGTEGMRYLAEWGRCCNVNGICGETPADCYVERGCQDAFGVCASNSTSAVSMSAAVSTSTPPGTMTSGTTASASTSTVAPAPACTGGSNAPGITDNLKGLCSYSCDYNHCPVGACGRTGPAAEPATGIPGCHGCPADNITEDLGYYEDLCKFTCSRGYCPPGACKYFEIGLKYQSNAET</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q985</accession>
    <name>E3Q985_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_01759</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091284.1">
        <property type="nucleotide sequence ID" value="XM_008093093.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q985"/>
    <dbReference type="STRING" id="645133.E3Q985"/>
    <dbReference type="GeneID" id="24407124"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01759"/>
    <dbReference type="eggNOG" id="ENOG502QT79">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008244_1_0_1"/>
    <dbReference type="OrthoDB" id="5284003at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051439">
        <property type="entry name" value="XlnR/Xlr1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47663">
        <property type="entry name" value="XYLANOLYTIC TRANSCRIPTIONAL ACTIVATOR XLNR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47663:SF1">
        <property type="entry name" value="XYLANOLYTIC TRANSCRIPTIONAL ACTIVATOR XLNR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="215"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="91"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="697"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="15"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="31"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="91"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="134"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="147"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ27264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="841" mass="93326" checksum="B2D94E45B78FC3EA" modified="2011-01-11" version="1">MSSSLADQDQQSPQHDQHDHDDHQPDHPVSVSLSPTASQHATAHAYASNSLQVLQAASDAAAAAAIQNVQNHLTTAAAAAAVVADEQQQQQQQQQQQQQTEQQPVDEQQQQHHLPMPPSIADHEQVHQQQQQHLPPPPHPHTPSQPPHQQLPQHQQHGPHTPTAAPTSTSPLDADDSLAAVSHGAMPAFPQAFAPMPHMPRDPTVNPKLTRLRRACDMCSQRKVKCDEAGPPCRPCAELNVECTFNRQLKRRGPPNKHAEAARAARRQRIEPDMSPTTAAAAFTSYAAAAVTPSPSPHNAAQALVSIAEGPARLDAESIAPLPILELLIDDFFTYIHPLAPFPHEPTFRHSFANREDRTNPEFLGLLASMVATLVASFPRSARQHLKTQHSTHLFPRAIVMIERCRDIALDTRGARWPLKQPKTLDDAATSYFLGLAAGYTFQTSRYRYFHAECLSLIRELGFRRPKHPNELPTFGNDDCSPDPLPFHHIKDQIGKRIFWCLLLGVRSFSQLGSSHADMVIAPSTPGLPYPALPEDVDDLYIMANEIVYPPESSVTLLTGYRFAIDIYTTMNAIVSVELVYGMSTLPWLDQMALLRDALIAAKDVIDRLPPELQLSASYEQSSGFGALDDAHLPYVPPAYPNNQPSNDVRNVIKNHPQRRRQLQYEIQKANIYVSQLATRSFYVELYFNLRDVHLANPNKDDQPPKGPDEKAAEDAEEARVFELMTAERELIVQNLLHVLGSISQRNLEPNGGSLINKIRQVASTLLNDTPERKGPVATKSEEALVKLIDVLLKLEGTGPSGSSMAGEHMTPQDEEEEMRNWAHLRDYQQRFTAHGFTGDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9G7</accession>
    <name>E3Q9G7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_01841</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091366.1">
        <property type="nucleotide sequence ID" value="XM_008093175.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9G7"/>
    <dbReference type="GeneID" id="24407206"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01841"/>
    <dbReference type="eggNOG" id="ENOG502RR5N">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_912192_0_0_1"/>
    <dbReference type="OrthoDB" id="4843499at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="305" mass="33538" checksum="206690FF3610CB82" modified="2011-01-11" version="1">MALSPEEVAHLHRQARRRAERAAAEMSFRSVSSDDYLKKLRAKRRPGRRHEVGDIPAAVEIGEEPLPPSQPEFRRPTGPERQRTHTRTQSASATIPGPQQRAASTPVSRRATLVGPISRNTPLKPHAPSQRYSGQHASSQPDLLMRAAQRQSVSTPGPATGLKAARSSPKPRPPRPRSSLSIFYPRKSVRRVASVGVISSRKVDPETGPTLRQPSHTRSKPAHATATSSEPPVRPGTTLIKRGSLRMLKDKIRRVASSFELRSTRTENTGLGNDDGLKHRSSRSLLLRPSRKLGSQLRLGTVSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9G8</accession>
    <name>E3Q9G8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADH:flavin oxidoreductase/NADH oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_01842</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091367.1">
        <property type="nucleotide sequence ID" value="XM_008093176.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9G8"/>
    <dbReference type="STRING" id="645133.E3Q9G8"/>
    <dbReference type="GeneID" id="24407207"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01842"/>
    <dbReference type="eggNOG" id="KOG0134">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012153_0_0_1"/>
    <dbReference type="OrthoDB" id="276546at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003959">
        <property type="term" value="F:NADPH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02933">
        <property type="entry name" value="OYE_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000138">
        <property type="entry name" value="NADPH dehydrogenase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="NADH OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893:SF91">
        <property type="entry name" value="NADPH DEHYDROGENASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="2">
        <location>
            <begin position="3"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ27347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="369" mass="41082" checksum="1AE663483D8CEFAC" modified="2011-01-11" version="1">MSKLFSPLAVGSVHLSNRLALAPLTRYRADDEWTPTPMMKEYYAQRACVPGTLLVSEATIISYRAVSRFNVPGIWTDAHIAGWKQVTDAVHEKGSFIYCQLWHLGRGGKMDVLQSLGLKLESSSAVPIADDTPTPVELSEADILDIIEDYATAARNAIEAGFDGVEIHGANGYLPDQFLQDNCNKRTDAWGGSIEKRARFHLEVTKAVINAVGAHRTAVRLSPYSDFQGMLMDDPDPTFRYLVEQLKPLGLAYLHLIEARISGNEDTDCGGQRTVKWLVELWNNASPVSIAGGLTAESARKAVEETYKQYDVILAFGRCFIPNPDLVFRIREGIELEKYDRTYFYTPKLPTGYIDYPFSPQFKSASSIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9N8</accession>
    <name>E3Q9N8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RanBD1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_02720</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091596.1">
        <property type="nucleotide sequence ID" value="XM_008093405.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9N8"/>
    <dbReference type="STRING" id="645133.E3Q9N8"/>
    <dbReference type="GeneID" id="24408085"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02720"/>
    <dbReference type="eggNOG" id="KOG0866">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044364_0_0_1"/>
    <dbReference type="OrthoDB" id="185618at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000156">
        <property type="entry name" value="Ran_bind_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045255">
        <property type="entry name" value="RanBP1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23138">
        <property type="entry name" value="RAN BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23138:SF142">
        <property type="entry name" value="RAN-BINDING PROTEIN 3B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00160">
        <property type="entry name" value="RanBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50196">
        <property type="entry name" value="RANBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RanBD1" evidence="4">
        <location>
            <begin position="318"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="184"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="74"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="139"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="225"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="244"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="262"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="288"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ27576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="490" mass="51046" checksum="CC5B76190584719C" modified="2011-01-11" version="1">MADDPQPGSPKSDPIYAKEDAETAAARKELKHTAISERPSADGTAAEITPSVPQNDDHKERPSSPKKKRAHDQVDEDKDVDEFDDKSVASSDSAKDRTARLEPEKKRHRDEVATSADAVPDSSAPPTAATAADSEAKENVTTQGISTTSQGPIKDEKRGASTSAFASSGFAKLAASSASPFGSLGGATKGSVFGGSASSASPFGGLSPSKPATPAPAPTPALSFGGTSAASSPFASVKPTSTNGGFGSAFGSAFGGGLGSKPLTSFSKTGESSFKTEKAAKPFGAPDSDADEGSDEDTDDVAEAASESGDKDEKEESDKEESKAVDDKKRTKLQKITVDDGEAGEATILQVRAKIFYLEKEVGWKERGSGMLKINVPEACVQFDEAGLPVPGSFDASGLEEDPEAGDNKGHKVARLIMRQDQTHRILLNTVILPVMQFQEKATLKSVGVMFTAFEGEEAKPVSVHVRMSAASAKSFLNEVGVIQRELSGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAL6</accession>
    <name>E3QAL6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_03048</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ27904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091924.1">
        <property type="nucleotide sequence ID" value="XM_008093733.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAL6"/>
    <dbReference type="GeneID" id="24408413"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03048"/>
    <dbReference type="eggNOG" id="ENOG502SQDE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076636_0_0_1"/>
    <dbReference type="OrthoDB" id="4188844at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="194" mass="20163" checksum="66DFB667ED4A9AF7" modified="2011-01-11" version="1">MADRTSRQAPPPGAPRRQVRRNLFQGLTRRPTGPTGASAAATTTSAGGAGGIVSAAAAGAGSGNGMAVATGGGSSSGASAETLRLDVDVLSDGGGAPVEIVVRDEHGEVELGELPTLVFDEADEVAATDDREESNKERQRLAEAVKQHQVNHTAIREQPEELLEAVRVSLRAKVAALAEDNWMYEAEPELPRAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>E3QB31</accession>
    <name>E3QB31_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">AP-3 complex subunit delta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_03213</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Adaptor protein complex 3 (AP-3) is a heterotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the adaptor complexes large subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ28069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092089.1">
        <property type="nucleotide sequence ID" value="XM_008093898.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QB31"/>
    <dbReference type="STRING" id="645133.E3QB31"/>
    <dbReference type="GeneID" id="24408578"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03213"/>
    <dbReference type="eggNOG" id="KOG1059">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001908_3_0_1"/>
    <dbReference type="OrthoDB" id="10264595at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030123">
        <property type="term" value="C:AP-3 adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017105">
        <property type="entry name" value="AP3_complex_dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22781:SF12">
        <property type="entry name" value="AP-3 COMPLEX SUBUNIT DELTA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22781">
        <property type="entry name" value="DELTA ADAPTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037092">
        <property type="entry name" value="AP3_complex_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="10">
        <location>
            <begin position="3"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="338"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="731"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="914"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="874"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="369"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="731"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="820"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="997"/>
            <end position="1006"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR037092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ28069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1016" mass="111319" checksum="21452A0FE427B207" modified="2011-01-11" version="1">MDVKATALLKLVYLEMVGHDMSWASFHVLEVMSSPKYHQKRVGYLAAVQSFRPDTEVLMLATNLLKKDLSSTHATTISLPMTTLPHIITPSLALSTLSDLLPRLGHSNPAIRKKTIVTLYRLALVYPETLRAAWPKIKERLMDKDEDPSVTAAIVNVVCELGWRRPHDFLPLAPRLFELLVDGGNNWMAIKLIKLFATLTPLEPRLVRKLLPPLTELIRTTPAMSLLYECINGIIQGGILGSADDISGREEIATLCVNKLRGMIMVDGDPNLKYVALLAFNKIVVTHPFLVAQQEDVILECIDSPDITIRIKALDLVQGMVSSDNLVSIVSRLMKQLKSSTPKRDRPGAPLRPDTGIDSDEEAQAEIRSPTKDQEEPPLPDDYRTDVIGRILTMCSQNNYISLVDFDWYIDVLIQLVRMAPTPRSIETELDSVAASGKSIAGDVSGRIGDELRNVAVKVHALRGAAVRAADLIIQQMNTDTPAGHHLSSASLKSTSWLVGEYANQLAFPEDTLDNLLRILSRTQKPDILTTSLQGVTKIFAFIAGNEGQPWTPEWKTKISLLLARVIHALEPLALHPNLEVQERSVEFVELLKLTAEATSGQAATSDEAHQEPPLLLTQAIPSLFQGWELNSVAVGAQRNVPIPEGLDLDEAIHPNLAHLLAQADVIPMGANEADDFEVYYHQRPAPTSVSSAEPAINRIADAPTEEVVSSYQQATEDSYLDADIVARRKAERNERNRDDPFYIGAPGTTPRTSTPIHNILQKENGPDLDIDSIPIMQLDLDKLGSSAPGPASPNRRPQPQPRQRQRVVIAADETLAGSGISTPRNYESENNSDSFTKSRAKKLRQGLLHVDSSTLGSLSLESDTGSSNAPFDYERQQREEAEMAQAMKEVERLRLEMQRANERIQVAQGVDVAGTVVKKKTKKSKDKEKEKGGTESVKPKKKKKKAVTEIAPPAVLLTGDAEDSGGGEDSALMPPPEAAVEGRENGQGAGPAVVVPKKKKKKKTTKMAEIAGDSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBI6</accession>
    <name>E3QBI6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_03469</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092345.1">
        <property type="nucleotide sequence ID" value="XM_008094154.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBI6"/>
    <dbReference type="GeneID" id="24408834"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03469"/>
    <dbReference type="eggNOG" id="ENOG502T4D1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1102697_0_0_1"/>
    <dbReference type="OrthoDB" id="4849892at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ28325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="250" mass="27268" checksum="51405EA815B03295" modified="2011-01-11" version="1">MADSQPPALHGRPRATPYRFFVRLRDRLELVLERFVDGDPTAQAGFERYKADRDRRWAERDARRMRKKKKKEKKVTAAAVAISVINGPTDETPVGDAASPGMDNVFPQNHADEETGLDAPKTGDKGKDKGKDNAPCQGDDDDDDDVGRAPGAAGGSTARRHTDAPPRGTQRSGTFSSLVGSTLGEQGRRKRKRPYARPGYFDPDPFPQGPSCGTDATVAEVGVGDEDRLEMNIPVELGRRSWTVPIGTAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBX5</accession>
    <name>E3QBX5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_03354</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092230.1">
        <property type="nucleotide sequence ID" value="XM_008094039.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBX5"/>
    <dbReference type="STRING" id="645133.E3QBX5"/>
    <dbReference type="GeneID" id="24408719"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03354"/>
    <dbReference type="eggNOG" id="ENOG502RVX3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060131_3_0_1"/>
    <dbReference type="OrthoDB" id="410198at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052523">
        <property type="entry name" value="Trichothecene_AcTrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791">
        <property type="entry name" value="GNAT FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791:SF16">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="96"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ28210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="243" mass="27472" checksum="0D3CF8F7EE4F93F4" modified="2011-01-11" version="1">MAKPAAAAAGFYIRPGTSTDLPAVLDVYMASFGNDWTIQRMHPRRREFPDDWRAWAHRFFYARYWGPEQQLFHVLAVPDPSSASGERVVAFMWWRRPYPTPEEKSAAEGPLTVRGWLKPVLLGLNSLLGYLWPPRCADPAMADFFEDTHIASDPIKNDPEHPRRKNAWYLSTLAVHPEFQGKGYGSLLVRGGLQQVDKEGVPAWLIGLGGVEPFYERLGFVVKGRANVGRLADWDGGAIMYRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBY2</accession>
    <name>E3QBY2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Serine hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_03361</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092237.1">
        <property type="nucleotide sequence ID" value="XM_008094046.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBY2"/>
    <dbReference type="GeneID" id="24408726"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03361"/>
    <dbReference type="eggNOG" id="KOG2551">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051938_4_2_1"/>
    <dbReference type="OrthoDB" id="414698at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019748">
        <property type="term" value="P:secondary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005645">
        <property type="entry name" value="FSH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050593">
        <property type="entry name" value="LovG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070:SF4">
        <property type="entry name" value="ESTERASE ALNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03959">
        <property type="entry name" value="FSH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine hydrolase" evidence="2">
        <location>
            <begin position="2"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ28217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="260" mass="29211" checksum="53A589163CA50101" modified="2011-01-11" version="1">MLRFLCLPGAYGSSDKLQVQLAPILKELTEDGTAQFHFIQGPCKAVPPPGFEDYFGAPPYYRFIEPDRDVEKSNSDDVLARIRDFPQCETPEDTMRDLMREGIATTHRSTDRAIKYLADIAAKRGPFDGIIGYSEGATVASTFMLYEQRRFKRSGIKPTFKYGIFFAGWPPVDPKTHALVLSDETDERIEARTLHIIGSLDPYVDGSTALYNMCDPDTAYLFDHAKGHTLPRDKDTIKELGDIVRQTKAEMQEEGILSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QC40</accession>
    <name>E3QC40_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">pH-response transcription factor pacC/RIM101</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_03572</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the pacC/RIM101 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092448.1">
        <property type="nucleotide sequence ID" value="XM_008094257.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QC40"/>
    <dbReference type="STRING" id="645133.E3QC40"/>
    <dbReference type="GeneID" id="24408937"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03572"/>
    <dbReference type="eggNOG" id="KOG1721">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012842_1_1_1"/>
    <dbReference type="OrthoDB" id="6155966at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000458">
        <property type="entry name" value="pH-response transcription factor pacC/RIM101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001875">
        <property type="entry name" value="pH-response transcription factor pacC/RIM101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050806">
        <property type="entry name" value="pacC/RIM101"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47257">
        <property type="entry name" value="PH-RESPONSE TRANSCRIPTION FACTOR PACC/RIM101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47257:SF1">
        <property type="entry name" value="PH-RESPONSE TRANSCRIPTION FACTOR PACC_RIM101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="77"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="107"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="382"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="536"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="9"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="382"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="397"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="437"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="491"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="536"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="560"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ28428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="585" mass="64002" checksum="7A4596FA11A0E766" modified="2011-01-11" version="1">MSTKQENESSASNSPKSSTPAPSTTTSNTSQSNSTSAEDNLICKWNACNLKFVSPEALYEHICERHVGRKSTNNLNLTCQWNSCRTTTVKRDHITSHIRVHVPLKPHKCEFCGKSFKRPQDLKKHVKTHADDSVLVRSPQDQGMNGYRAQPGKASSSYYDHNGHIRTNSAAFAHQAGHASYYAPQPSTNYGLYFNQQPLNPPRSEYIGHHHGGYDNRKRAFDMVDDFFAHAKRRQVDPTSYQQVGRSLLPLHGALGLHAGPMPGSDYMSAPPQHHVQHHVQGPPSGPGPLTQQYYLPPMPNARTKNDLVQIDQILEQMQSTVYENANQATQGIHIHGQNTFDLRHSPSPPGGHRGSHAGIPVSHDAYHAVSAAHMASPLTAVSSTGTPAVTPPSSTMSYTSGHSPSPSSSGMSPQSRHSSTASSVMYPNLPAVSSVFPGQSTASTLGPSFDSNERRRYSGGMLQRAAPSSPRSPIFLEDSSAATTPKAESVASSVGSPASDSDMSEGAREREEKYDQWLENMRTIEALREYIRDRIDRREYSEEPADQESKSSPKASRLKSPEPMEVDAKPAPAAPLYPILRMPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCL0</accession>
    <name>E3QCL0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-phytase</fullName>
            <ecNumber evidence="2">3.1.3.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_03742</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histidine acid phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.8" evidence="2"/>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092618.1">
        <property type="nucleotide sequence ID" value="XM_008094427.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCL0"/>
    <dbReference type="STRING" id="645133.E3QCL0"/>
    <dbReference type="GeneID" id="24409107"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03742"/>
    <dbReference type="eggNOG" id="KOG3720">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030431_3_1_1"/>
    <dbReference type="OrthoDB" id="10257284at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016158">
        <property type="term" value="F:inositol hexakisphosphate 3-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033379">
        <property type="entry name" value="Acid_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050645">
        <property type="entry name" value="Histidine_acid_phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567:SF110">
        <property type="entry name" value="2-PHOSPHOXYLOSE PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567">
        <property type="entry name" value="ACID PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00616">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ28598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="515" mass="57022" checksum="4B942C0DAB0B229B" modified="2011-01-11" version="1">MTTLEPRQPYTDAELRQLYPPHLKLQLVQILLRHGERTPVTPRFQNTGLPPYWPYCRAVRHLRSAVLDPDTGEYSYLDWKRRLETFASDDDSPIIAAGPNAELDDICDMGMLTDRGRETTRDLGRRLRRLYVDGLSFLPADLASADSLYLRSTPVPRALESLQQALSGLYPATHRAPNLPPLTILTRAPQDETLFPNDGNCRRFAALSRAFAQRAAERWNDTPEMDYLNKKFGKWMPNGARIAVDSKPRLSGIMDTINATRAHGPQTKLPSEFYDPKAISIIERIGVEEWYGGYAESQEYRTLGIGGLMGDVVARMVGSVEHTPADGECEIKQSGTAPRPIRFGMSGCHDTTLAGVLASLGAFGPDQWPPFTSHIAVEMFRDARVPAVGTSTELPAAPAPKNGSWFSSWFSFGRTSAPSPGTAPPGIGRKTMPELTDAEKDKLDGYYVRLRYNDAPVTIPGCKTPGNHLENDESFCTLAAFKSIVDKYTPVSWRDQCRMNANASAFPAKPEPAGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCQ0</accession>
    <name>E3QCQ0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Nuclear condensin complex subunit 3 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_03782</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CND3 (condensin subunit 3) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092658.1">
        <property type="nucleotide sequence ID" value="XM_008094467.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCQ0"/>
    <dbReference type="STRING" id="645133.E3QCQ0"/>
    <dbReference type="GeneID" id="24409147"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03782"/>
    <dbReference type="eggNOG" id="KOG2025">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004446_0_1_1"/>
    <dbReference type="OrthoDB" id="27187at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000793">
        <property type="term" value="C:condensed chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000363">
        <property type="entry name" value="Nuclear condensin complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027165">
        <property type="entry name" value="CND3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025977">
        <property type="entry name" value="Cnd3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14418:SF5">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14418">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12719">
        <property type="entry name" value="Cnd3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nuclear condensin complex subunit 3 C-terminal" evidence="9">
        <location>
            <begin position="631"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="574"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="994"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="574"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ28638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1043" mass="115231" checksum="518BD2D9E2F3A22D" modified="2011-01-11" version="1">MPARVSTRSTRTSAAVSHKSSAATVGSRASTASRSSSLALDVPTERPDSELRGQVCAVFRDAQKNTASHRKLVVTLRKIQEACAYEPTSLKKSTANEFDEEAFNSEFVRCVLRVMPIKKTETVGEKTIRFIGSFLRHANDKDNEILGEIDEDASVMPETPSTRLTSYLMSTVLPLMVAKDKFVRYRSTQLISHIINSLDAIDDDLFQKLRHSLLKRIHDKEAMVRAQAVLGLGRLAGNQVNAADEDDDDDDASGLLEKLLEVVQNDPSADVRRSLLVNLPILPATLPYLLERARDQDALTRRAVYSRLLPALGDFRHLSLSMREKLLRWGLRDRDENVRKSAGRLFRERWIEDCAGVAPPEEGAPPAEPSPPNFDGLLELLERIDVVNSGVENGVALEAMKGFWEGRPDYREAVTFDNQFWETLSAESVFMARSFNDFCRNEGNGKFESLVEEKLPEVTTLAFYLERYISVLIEAIKRVSEIEGEEDEEEDTVEQEFIVEQLLHIAITLDYSDEVGRRKMFALLRQSLSVPELPDDVTKLTINVLRDICAPDNAGEKEFCSVVLEAVADVHDTIVDDPAPDDRTEDSFHSARSEVSGDVTPTRGGSRQKSPELSEEEARAKAVKEIMINMKCLHIVQCMLSNVAGNLQQNDHLVSMLNNLVVPAVRSHEAPVRERGLVCLGLCSLLDRSLAEENLTLFMHFFTKGHTALQITALQILTDILNVHGAQLLSSTPALLKIYIKALKSGTKSPEVQAAATLAVSKLLLGRVVTDPEASAEMLKTLVVQYFDPVTATNQSVRQALNYFLPVFCYSRAENQDLMRTVALDALHALLNVRESLEDDDADVDEDMESLTTIGACLVDWTDPRKCFNPATGLDLEKKTVNGDIHLDFALDILDRLNSSISKDEKKVVASLLGKLYISPTSTEEKIREVYDEVTIAVNDRLISDTTGRNALNKVHVSLGKIVATLGEQQDGEPRRTSRSVSVAASVAGSVAGSVAGSVAPSEKNEPDIKEEDEDSDGTVIQTTIKDDGNSLVSELLSDEEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDG3</accession>
    <name>E3QDG3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Host-nuclear effector</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_04079</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092955.1">
        <property type="nucleotide sequence ID" value="XM_008094764.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDG3"/>
    <dbReference type="STRING" id="645133.E3QDG3"/>
    <dbReference type="GeneID" id="24409444"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04079"/>
    <dbReference type="eggNOG" id="ENOG502T5Q7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_796958_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180326" description="Host-nuclear effector" evidence="2">
        <location>
            <begin position="21"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ28935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="348" mass="39079" checksum="D4F0A68A26E9E71B" modified="2011-01-11" version="1">MRFTTATLITLSFLAGNVVSAPTAPINDVAAPVEARAADFVDGAHLEARKNKKKKKEGKKDKKAKDNARDLTELEDRDADDVTIVEIRTPEFVADDAHNLEARKNKKKKKKGGKKDKKEKKAKDNARDLTELEARDEEADDAAQLEARKNKKKKKGGKKDKKEKKAKNNARDLTELEARDEEAEDAAQLEARKNKKKKKGGKKDKKEKKAKNNARDLTELEARDEEADDAAQLEARKNKKKKKGGKKDKKEKKAKNNARDLTELEARDEEADDAAQLEARKNKKKKKGGKKDKKEKKAKNNARDLTELEARDEEAEDAAQLEARKNKKKKKGGKKDKKEKKAKDAGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>E3QE65</accession>
    <name>E3QE65_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Replication protein A subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">GLRG_04297</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">As part of the replication protein A (RPA/RP-A), a single-stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the heterotrimeric canonical replication protein A complex (RPA).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the replication factor A protein 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093173.1">
        <property type="nucleotide sequence ID" value="XM_008094982.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QE65"/>
    <dbReference type="STRING" id="645133.E3QE65"/>
    <dbReference type="GeneID" id="24409662"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04297"/>
    <dbReference type="eggNOG" id="KOG0851">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012393_2_1_1"/>
    <dbReference type="OrthoDB" id="1751331at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140445">
        <property type="term" value="C:chromosome, telomeric repeat region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005662">
        <property type="term" value="C:DNA replication factor A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033260">
        <property type="term" value="P:nuclear DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="term" value="P:telomere maintenance via telomerase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd04474">
        <property type="entry name" value="RPA1_DBD_A"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="RPA1_DBD_B"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="RPA1_DBD_C"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="RPA1N"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Replication protein A subunit"/>
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        <property type="entry name" value="Replication protein A subunit"/>
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    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047192">
        <property type="entry name" value="Euk_RPA1_DBD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
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        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
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        <property type="entry name" value="Rep_factor-A_C"/>
    </dbReference>
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        <property type="entry name" value="Rep_factor-A_N"/>
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        <property type="entry name" value="REPA_OB_2"/>
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        <property type="entry name" value="Rfa1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00617">
        <property type="entry name" value="rpa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47165">
        <property type="entry name" value="OS03G0429900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47165:SF4">
        <property type="entry name" value="OS03G0429900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04057">
        <property type="entry name" value="Rep-A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08646">
        <property type="entry name" value="Rep_fac-A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16900">
        <property type="entry name" value="REPA_OB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Replication factor-A protein 1 N-terminal" evidence="12">
        <location>
            <begin position="7"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="OB" evidence="11">
        <location>
            <begin position="187"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="Replication protein A OB" evidence="14">
        <location>
            <begin position="296"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="Replication factor A C-terminal" evidence="13">
        <location>
            <begin position="452"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="146"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF16900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EFQ29153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="608" mass="67727" checksum="8FFD3499229A5DB6" modified="2011-01-11" version="1">MDVESKITKGALDAVFNDPEGANTKFPVPVLQCLQIKPLAAQAGGGAERYRIVLSDVNNYVQCMLATQVNHVVHENKLVRNCIVRITQYQANSVKGKNILIILGLEVIEQLGTPDKIGEPQPFEAKPPPAAANTTIGGQNFYGVKQEETKPKPQQSIPSRSAGGATGQHGSSNIYPIEALSPYAHKWTIKARVTQKSDIRTWHKPSGEGKLFSVNLLDESGEIKATGFNEQVDQYYDMLQEGGVYYISSPCKVQLAKKQFTNLPNDYELTFERDTVIEKAEDQSSVPQVRFNFCNIQELQEVEKDATVDIIGVLKDVDEVSQIVSKSTGKPYEKRELTLVDDTNYSVRVTIWGKSATNFDAKPESVVAFKGTKVSDFGGRSLSLLSSGTMSIDPDIPDAHRLKGWYDSSGRNDTFSSHNNMASMGNATGRKDQDKSILQVKEENLGMEQQDYFNLKATIVYIKQDNFAYPACMNEGCSKKVTDMGDGTWRCEKCDVSHPKPEYRYIMSVNVCDHTNQLWLSCFDDVGRVVMGMSADQLMALREEDETKMAQAFEEANCRKLNFRCRAKMDTFGESQRIRYQVMSASPIDYKAEGAKLAELIKQFGISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QE97</accession>
    <name>E3QE97_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">glutamate-5-semialdehyde dehydrogenase</fullName>
            <ecNumber evidence="2">1.2.1.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Glutamate-5-semialdehyde dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Glutamyl-gamma-semialdehyde dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_04329</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the NADPH dependent reduction of L-gamma-glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-glutamate 5-semialdehyde + phosphate + NADP(+) = L-glutamyl 5-phosphate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19541"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="ChEBI" id="CHEBI:58274"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the gamma-glutamyl phosphate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.41" evidence="2"/>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093205.1">
        <property type="nucleotide sequence ID" value="XM_008095014.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QE97"/>
    <dbReference type="STRING" id="645133.E3QE97"/>
    <dbReference type="GeneID" id="24409694"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04329"/>
    <dbReference type="eggNOG" id="KOG4165">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030231_0_1_1"/>
    <dbReference type="OrthoDB" id="1934954at2759"/>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004350">
        <property type="term" value="F:glutamate-5-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07079">
        <property type="entry name" value="ALDH_F18-19_ProA-GPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000006">
        <property type="entry name" value="Gamma-glutamyl phosphate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00412">
        <property type="entry name" value="ProA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020593">
        <property type="entry name" value="G-glutamylP_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012134">
        <property type="entry name" value="Glu-5-SA_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000965">
        <property type="entry name" value="GPR_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001221">
        <property type="entry name" value="PRK00197.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00407">
        <property type="entry name" value="proA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11063:SF8">
        <property type="entry name" value="DELTA-1-PYRROLINE-5-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11063">
        <property type="entry name" value="GLUTAMATE SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000151">
        <property type="entry name" value="GPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01223">
        <property type="entry name" value="PROA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="12">
        <location>
            <begin position="9"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00059423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00060997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00075718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00077451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ29185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="449" mass="47343" checksum="AE1B16FAF74DAC12" modified="2011-01-11" version="1">MSLTNASPADAAKGAKSASHTLATLSAEARNDALTAIHAALADARDEILAANARDLDLARKAAADGQLSQSLVSRLDLGKKGKFEDMLKGILDVRGLEDPVGKVTLRTKLDDGLILERVTCPIGVLLIIFEARPEVIANIASLAIKSGNAAILKGGKESTESFIAISKVISAALDKSQVPNSAIQLVITRDVIPQLLALDQYIDLVVPRGSNELVRYIKESTKIPVLGHADGLCSIYLTDSADPSVAAAVIVDSKTSYPAACNSLETLLVQESALESVFPAAAEALVAKGVTLHCDAKSKATLQSNILGDAAAKVVDAKDADFDTEFLSLDLAVKVVASLDEAIGHINLHGSKHTEAILTSSSEDAERFMAAVDAAGVYWNASTRMADGMRYGFGTEVGISTNKIHSRGPVGLEGLMIYKYKIRGHGQVSLAYGEGEGQKPFKHEKLSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3QF29</accession>
    <name>E3QF29_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sorting nexin-3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_04611</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Required for retention of late Golgi membrane proteins. Component of the retrieval machinery that functions by direct interaction with the cytosolic tails of certain TGN membrane proteins during the sorting/budding process at the prevacuolar compartment. Binds phosphatidylinositol 3-phosphate (PtdIns(P3)).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Prevacuolar compartment membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the sorting nexin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093487.1">
        <property type="nucleotide sequence ID" value="XM_008095296.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QF29"/>
    <dbReference type="STRING" id="645133.E3QF29"/>
    <dbReference type="GeneID" id="24409976"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04611"/>
    <dbReference type="eggNOG" id="KOG2527">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057172_2_1_1"/>
    <dbReference type="OrthoDB" id="5227681at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031901">
        <property type="term" value="C:early endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030904">
        <property type="term" value="C:retromer complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034499">
        <property type="term" value="P:late endosome to Golgi transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07295">
        <property type="entry name" value="PX_Grd19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1520.10:FF:000030">
        <property type="entry name" value="Sorting nexin-3, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042138">
        <property type="entry name" value="PX_Grd19_PX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051074">
        <property type="entry name" value="Sorting_Nexin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45963">
        <property type="entry name" value="RE52028P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45963:SF2">
        <property type="entry name" value="RE52028P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PX" evidence="13">
        <location>
            <begin position="21"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ29467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="142" mass="16582" checksum="9105947E5A2F7110" modified="2011-01-11" version="1">MQAMPDNRQQSFDEIYGPPENFLEIEVRNPRTHGMGRSMYTDYEIVCRTNIPAFKLRASSVRRRYSDFEYFRDILERESARVTIPPLPGKVFTNRFSDDVIEGRRAGLEKFLRIVVGHPLLQTGSKVLAAFVQDPNWDRNAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFE6</accession>
    <name>E3QFE6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pre-mRNA-splicing factor 38B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04728</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093604.1">
        <property type="nucleotide sequence ID" value="XM_008095413.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFE6"/>
    <dbReference type="STRING" id="645133.E3QFE6"/>
    <dbReference type="GeneID" id="24410093"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04728"/>
    <dbReference type="eggNOG" id="ENOG502S07H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038073_1_0_1"/>
    <dbReference type="OrthoDB" id="2431475at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40132">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR 38B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40132:SF1">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR 38B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="296" mass="33405" checksum="FF5F502EE3562574" modified="2011-01-11" version="1">MPNDNLLTDEYVAELLAKEADDCSLKYSSMGMDAFRTDKKPANLPKPNTRFLRHIIKDTNTHNKNLLAKEAAESRARLKDLEHADEKERRRKAGPQDIRRRQMGDIKAILGDRKDTPESLFAVYYSNTATVEPRSAAPFKWERSGSGRRERERESAGGGGGGDMSDSDPLDDFIGPAPAQQVRSRGRGAAAGTSGIDKRFETDYDPKADVETAEDAAGAGDWDDAVEAFRDRQKWRQNQEQRMRAAGYSDETIKKWREGGEQRDERDVRWAKAGEKREWDRGKEEEGVSGLFSEFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFK6</accession>
    <name>E3QFK6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">PPE family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_04788</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04788"/>
    <dbReference type="eggNOG" id="ENOG502RUHX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000008782">
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ29644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="259" mass="27132" checksum="2F3C732A0FD873F4" modified="2011-01-11" version="1">MFLPSLAIPSISVPDLSVPSVALPSISLPAISIPSLTVPSLSVPSLNVPSIAVPSVTIPSIAASAISPPASASSTAAPGVTALFDILGLIGTTLSTIDTELEEIFQPNVDIFDTAVLDRISELVNSLGTTGPLYSAISSALAQAQNFGTTLSPSDSETLIRDFNNDVVQRYSQVLQGLESRRDQIAQASSAALTNGVGGATTIMNRIFNNLNLGLVRQIDLNNQLIRVLDPAFKPQGVEVTSSLQILLKLSIDLYLPRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04929</name>
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        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
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        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
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        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFV0"/>
    <dbReference type="STRING" id="645133.E3QFV0"/>
    <dbReference type="GeneID" id="24410294"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04929"/>
    <dbReference type="eggNOG" id="ENOG502RPZR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_542916_0_0_1"/>
    <dbReference type="OrthoDB" id="5244495at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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        </location>
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            <end position="185"/>
        </location>
    </feature>
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            <begin position="283"/>
            <end position="296"/>
        </location>
    </feature>
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            <end position="469"/>
        </location>
    </feature>
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        <location>
            <begin position="491"/>
            <end position="516"/>
        </location>
    </feature>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EFQ29785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="516" mass="58350" checksum="05C5F389C68A9582" modified="2011-01-11" version="1">MGGKVWSDNEERVFWRIIVPQSQKRIATGPAHTKTWEELAPLMQSLMGVNAKRTYTHLGLCKSPITRPLHCANIHQVEHFFQNIDKARVSPNAGVFVREYQQAVNRNLKATEEERADKAKVDGQGDDAASMVNVYQENDCQDGTNLSYCPSEVADGVHQCADDFEDEEGDKENRPLDGSPGERVRYQAPPQYRPAPEADMGLDNEYGQGIPVRTSPPVERLILEEIRQPHDRGLAANMNSYNEVSEMQIRSPVEYSPYESAPSRALKHRNNHRAHPYADVRPQRHGRNAKKGHGRVHSQALQGNNAYYAAPSSYCSSPGYYTPTGFGCHVPPMEYYDYGYHGENFHPHSEYHKNPQHAPSHPMVFYDQAPGHFHGPYGYEPCHPTLHGFGDSRDWKFPGRNSSAMEANYEIPESRDFSWTSYNDRSYGLMEGEYPSPKSRSSTARDHDSFTPGNIQRPASSASDSQSPVLQARYQARHSGSYTESPQLPAEEPKRQLVATRDKEFEPPKTSDWRQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QG49</accession>
    <name>E3QG49_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">LCCL domain-containing protein</fullName>
        </submittedName>
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    <gene>
        <name evidence="4" type="ORF">GLRG_05028</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
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        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
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    </reference>
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    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05028"/>
    <dbReference type="eggNOG" id="ENOG502QUEX">
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    <dbReference type="OrthoDB" id="441660at2759"/>
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    <dbReference type="Gene3D" id="2.170.130.20">
        <property type="entry name" value="LCCL-like domain"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="LCCL"/>
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    <dbReference type="InterPro" id="IPR036609">
        <property type="entry name" value="LCCL_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31331:SF8">
        <property type="entry name" value="LCCL DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G02970)"/>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR31331">
        <property type="entry name" value="LCCL DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G08630)"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF03815">
        <property type="entry name" value="LCCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00603">
        <property type="entry name" value="LCCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69848">
        <property type="entry name" value="LCCL domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50820">
        <property type="entry name" value="LCCL"/>
        <property type="match status" value="1"/>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="390"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
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            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="459"/>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="501"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="domain" description="LCCL" evidence="3">
        <location>
            <begin position="217"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EFQ29884.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="660" mass="73505" checksum="8EBAAEC3EFC75AA5" modified="2011-01-11" version="1">MVDGRHEREPLLSIMERQQAHEPANQAEPIEHPDAPLGDSPRRELEVDDDSSPSTPRFMQDEGHWKRWRWVPYPVRRTVKAAAKWSKGPPNPQDYKIKPILPQVQEFPLVLVDRCLRKSKHRFGFVFFYAAIWIIAFALVKRSETFATEIEGWGAPQQIGCGATYWGRGNNCGLNGADCRPFNGSGFPFRCSANCAGYMVLNPRAVGDQEIVYEPLVVGGPSDNSSSPIYRGDSFLCGAAIHAGVISNENGGCGVVRLVGRHEGFVSSERNDIQSIGFDSYFPLTFTFEPGIECKARDLRWMLLAVSVVFTTVLSLFTASPALFFFSVFVGVFWHVGLASDPPNHYSVADLVSNIIGKFIPAMFCAWVIYDKMGVRRTLTGLTAQIEKTVLWLGGCWVGALSNYTFSWIPIQRLNAHDLNQQPGAKAALAVIIIVLVVIVVQQVWYFRQEGRLLRYLKLYLLFLGGILVCLVLPDLSLRIHHYILALLLLPGTSMQTRPSLLYQGLLVGLFINGVARWGFDAVLQTPAALQGDAQHGSVLPSILPPVIDLSQGMWSINFTWNSPPAGAQYDGISVLVNDVERFRSYFDDGPVPAKSFVWTRESELGLNEYVRFGFMEGSTSYDFTKAGIWNAEGKWIDMKPGPSMVRARSLGDEDESVPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGC4</accession>
    <name>E3QGC4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_05056</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ29912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093932.1">
        <property type="nucleotide sequence ID" value="XM_008095741.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGC4"/>
    <dbReference type="STRING" id="645133.E3QGC4"/>
    <dbReference type="GeneID" id="24410421"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05056"/>
    <dbReference type="HOGENOM" id="CLU_2108841_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ29912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="115" mass="11491" checksum="C7892872436D7FDB" modified="2011-01-11" version="1">MLGAADGLEGVGWPLSPYCRAHACGQEACGERTAGASGFCQAHARCRRPGCANGVDARAPDPTLCEEHNRNGPGRTVRRGVLNLEPFGYGGGGGGGGGGGGGWPGLGNWGINATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGS6</accession>
    <name>E3QGS6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">peptidyl-tRNA hydrolase</fullName>
            <ecNumber evidence="1">3.1.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_05208</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>an N-acyl-L-alpha-aminoacyl-tRNA + H2O = an N-acyl-L-amino acid + a tRNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54448"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:13883"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59874"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:138191"/>
            <dbReference type="EC" id="3.1.1.29"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PTH2 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="1"/>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ30064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094084.1">
        <property type="nucleotide sequence ID" value="XM_008095893.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGS6"/>
    <dbReference type="STRING" id="645133.E3QGS6"/>
    <dbReference type="GeneID" id="24410573"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05208"/>
    <dbReference type="eggNOG" id="KOG3282">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073661_0_0_1"/>
    <dbReference type="OrthoDB" id="1733656at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:peptidyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02430">
        <property type="entry name" value="PTH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1490.10:FF:000001">
        <property type="entry name" value="Peptidyl-tRNA hydrolase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1490.10">
        <property type="entry name" value="Bit1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023476">
        <property type="entry name" value="Pep_tRNA_hydro_II_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002833">
        <property type="entry name" value="PTH2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00283">
        <property type="entry name" value="arch_pth2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12649">
        <property type="entry name" value="PEPTIDYL-TRNA HYDROLASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12649:SF11">
        <property type="entry name" value="PEPTIDYL-TRNA HYDROLASE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01981">
        <property type="entry name" value="PTH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102462">
        <property type="entry name" value="Peptidyl-tRNA hydrolase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="40"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="45"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ30064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="235" mass="24971" checksum="F5141A9A26527176" modified="2011-01-11" version="1">MASEAVVISTSIVALMTGFILGVYSIRGYLISPELRAEARANTDDPVESDESDIDEDDTVLDHAPNWANGEAADRRDGLRQRNIASSEKTASSKTSKKPNPSAAPLADSNEECKLVLVVRTDLGMTKGKMAAQASHATLACYKSLSRAAAKDPSSSAANILKRWERLGQAKIAVQIKDQDEMLELMGKARSLGVTSEVIADAGRTQIEAGSLTVLGVGPAPRSLVDQITGHLKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHA2</accession>
    <name>E3QHA2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Exocyst complex component Sec3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_05408</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SEC3 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697348">
        <property type="protein sequence ID" value="EFQ30264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094284.1">
        <property type="nucleotide sequence ID" value="XM_008096093.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QHA2"/>
    <dbReference type="GeneID" id="24410773"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05408"/>
    <dbReference type="eggNOG" id="KOG2148">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002075_1_0_1"/>
    <dbReference type="OrthoDB" id="27109at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005546">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13315">
        <property type="entry name" value="PH_Sec3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.90:FF:000003">
        <property type="entry name" value="Exocyst complex component Sec3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028258">
        <property type="entry name" value="Sec3-PIP2_bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048628">
        <property type="entry name" value="Sec3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019160">
        <property type="entry name" value="Sec3_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16092:SF14">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 1 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16092">
        <property type="entry name" value="SEC3/SYNTAXIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15277">
        <property type="entry name" value="Sec3-PIP2_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20654">
        <property type="entry name" value="Sec3_C-term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09763">
        <property type="entry name" value="Sec3_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01313">
        <property type="entry name" value="Sec3-PIP2_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst complex component Sec3 PIP2-binding N-terminal" evidence="6">
        <location>
            <begin position="58"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="176"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="504"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="182"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="200"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="218"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="313"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="362"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="424"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="553"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="587"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="601"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ30264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1408" mass="155912" checksum="6FFCF3C19EC70816" modified="2011-01-11" version="1">MDSRAQRFEDEKRRIIESCFTKKDVDGSLLETYITHIRITEYSSHPTSPPPPQARTPETQKPRVIIVAVRKSGRVRMHKTKENANGSFSIGKTWNLDDLSAIESFTGPSANPNFREWAGDTGFVVTLGKPYFWNAQSDKEKKFFIASLVKIYGKYTGGKNPELLGFDPSEIAQILRNDRRPPPPGQLSFKPPPSTLDAASGQSNLAVNTAPSNYGTPSPGPPGPRRPPPLNGMPSHSPVGSMASSFSQDPPTLRRYGNQSQESFAPSLGARSEDASSLPPRSRNGMPGSGAMGRFAEQPSEPVLAPPPPISEEGGRPPERKRPPMDPARPQGLADRDLVPAPLISPGMRRDQVAPPPRSTARKNSISQRSDVGSYRDNRPVTPLTPVDPRTADFPPTLRTPEPNGGATPTRPTPAIVSPSSETPVPPAPVSPITTSPPPAPSPAPLPPVDEPIPKAPAASVSPPVPEPPAEPEEESRPGLGPMIKSKKSKGDLAGVLWKAASAATAFRPRPGGAGERLRQLAAKSAEPAEGITTVFQPPPRPTSSNDPKRAASPEVAAEKAASPAPSAAPTEPSKRTSGVPEVKITLPNSSRPTSVQPSIKEPKKPDESTANEESRKSIVVGNDAKYLASLGIDPTVLDNKSGEFTKWLDYFGWVPGEQMRSRNVEDMRTELERELNKAQAGGWLARFQEEDDRVEAIKRGIDLAVAECEEMENLLTLYSVELSTLSDDIAYIEAQGQGLQVQTANQKLLRKELESLLETTTITTADLNALKAAPLEDLGGLDDIEMSLVTLYKAMIKIDPSLLGGEPRKSEDLVGEGDQAVGLENTDYGKMRIVQEKKEMYRQESAAFSRRLVGYMAQQFDVAYNEVNKALREALSRKVDSRHHDIGRDMLWKYSPLIKYSKDVDPANWDRMIQVYQDKSHPVYKNEFRQVLEAWKRNARKMTADETTELLFSFEVEKQQEGKATTVRKLTVKRSQTLAKSLRSPIDTASRTNLKEAAGTENRSFPYEVFGHVLDDLLPLVEMEQNFIVDFFHATTLEQSDFPDLVAASRPKDRRGGDLRRHRLMEPDRDLARRVTKAMEVIFMFLETEVAKLIEWVIQTDPLQGAGVLAVLERNLVDYQQSNQEFLNAMLQKLHDVLESRFKKFVDEQIRAIEETKVKINKRKGVISFIRVFPQFSNAVENILTGIDPNLAVRKTVDREYGRILKSMFDSLKIIARENPAVSVGAAGADPEDKEALNFHILLIENMNHFLEEVNTHGLDVLEDWREAATNELNEHMGLYLNAVMRRPLGKLLEYIENIEGQLQSGKPGSSIAAQPSNSKSTFHKVLATYDAREVRKGIETLRKRVEKHFGDADDLALSQKLVTKVLRECERFYGEVELRISRITADVYGGDVLFEWPRAEVKAGFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHL2</accession>
    <name>E3QHL2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">NCS1 nucleoside transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_05494</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697349">
        <property type="protein sequence ID" value="EFQ30350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094370.1">
        <property type="nucleotide sequence ID" value="XM_008096179.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHL2"/>
    <dbReference type="GeneID" id="24410859"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05494"/>
    <dbReference type="eggNOG" id="KOG2466">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021555_3_1_1"/>
    <dbReference type="OrthoDB" id="2018619at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015205">
        <property type="term" value="F:nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11482">
        <property type="entry name" value="SLC-NCS1sbd_NRT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4160.10">
        <property type="entry name" value="Hydantoin permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045225">
        <property type="entry name" value="Uracil/uridine/allantoin_perm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30618">
        <property type="entry name" value="NCS1 FAMILY PURINE/PYRIMIDINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30618:SF15">
        <property type="entry name" value="NICOTINAMIDE RIBOSIDE TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="194"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="282"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="338"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="380"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="402"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="446"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="488"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="541"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ30350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="564" mass="62187" checksum="BEE87407FCD838FB" modified="2011-01-11" version="1">MMKAAALLRRMQVSRETDVVTTAYMNRDTRPLPPDRRTYGPWQFVGLWVVTGSFNIGGWTTGSSLIALGLNVWQAMLTVIVGHCLVGLICVLAGGPGAKWHIGFSILQKSSWGMYGALFPLVQRIVLSFIWYSTQVYWGGQCVRTFISSMAPSFNKLDMPLANGTMTVADFIGFIIFSLLCLPLIYIRPERYHVPFLVAACTVIPTVFALLIWCLATARGAGPMLTDITSTAGVQQARGSHLAWMLALGICTNIGGISTHIFSQSDFTRFARRPHDQLVSQLVFVPLNTIIVAFIGIVCTSCAAQLFPATEGTLVWEPYRFLDAMQAHYGNSAGVRAAVFFASLAFIFAQFGIAVAENALSNGIDLSALLPRFFNLRRGGYLTAAVAFIMQPWQLLNGASKFLTVMGGYGVFLGSMTGVMFADYYIVRQRKLKLTHLYEATSQSIYWYRGGVNWRAGVAWTLGTFSLLPGFVRRVQEPTVEERGWSHLYYLAWPLGCTLAVASYCLLNRVSPIESPCVVDDADYFGTFGPLEETVLDGCEQTPSKVSAEDKETKSPYMDQENIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHN4</accession>
    <name>E3QHN4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05516</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697349">
        <property type="protein sequence ID" value="EFQ30372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094392.1">
        <property type="nucleotide sequence ID" value="XM_008096201.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHN4"/>
    <dbReference type="GeneID" id="24410881"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05516"/>
    <dbReference type="eggNOG" id="ENOG502S92K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064039_0_0_1"/>
    <dbReference type="OrthoDB" id="2135488at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052358">
        <property type="entry name" value="Aro_Compnd_Degr_Hydrolases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35563">
        <property type="entry name" value="BARREL METAL-DEPENDENT HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G16240)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35563:SF2">
        <property type="entry name" value="BARREL METAL-DEPENDENT HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G16240)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="1">
        <location>
            <begin position="47"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="325" mass="35896" checksum="1612C8DA8913FDE9" modified="2011-01-11" version="1">MALIHPLIAPSSTRHDEKLVPRVSTTSAAATRRRLTLPERIPRGAWDSHMHVVNPTAYPLAKEAIYCPKTHRLDQALSFEASVGIDNMVLVQPSIYGNDNACLLDALRALGPRRGRAVVAFEPGTVPESTRREWHRLGVRGVRINLSSVGRSLDAAELGELLRRYADDCRPLDWVIQLYVPMAMMELLEPVVPTLGGVRVCVDHLGHPSAGDMAASGGDPYDMRGFASLARLLQAGSTYVKLSAPYRLSSRADHADLEPMAREVLRLRGGDRVVFATDWPHTRFEGLDIRPWIETVLGWCGNDDVLVDRLFRGNAEALWNTRGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHR1</accession>
    <name>E3QHR1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05543</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697349">
        <property type="protein sequence ID" value="EFQ30399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094419.1">
        <property type="nucleotide sequence ID" value="XM_008096228.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHR1"/>
    <dbReference type="STRING" id="645133.E3QHR1"/>
    <dbReference type="GeneID" id="24410908"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05543"/>
    <dbReference type="eggNOG" id="ENOG502RIYX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057547_0_0_1"/>
    <dbReference type="OrthoDB" id="4500473at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="314" mass="33991" checksum="B2B8A4E423153B14" modified="2011-01-11" version="1">MPMNMMKPERKTYFILRSTDYKPDGLIQLGQLIEDPHTPYRRLAPPIRPLPADTVHVSLRNDWSLEKSKGAAGELGVFAQFLAVITAEASTHASNEFTQSWSAAQLETAFLELGTGKESGYVTSSVQKAAVQKCLTREGFFKKMVLSKKILYMITGIKIARRPGQVSYGMSKTTSGAVKLGADPGTGGMVTAGAQGRLDRSNSIVESSTPDDDFVFAYRLRKVHVNFSSNKSLLGKDVFGAELHGHGAGGGGSDTSSEEESDEEVPEEVVVDVDELEKVLVEKEDFGDSLPARNEKIDGIDEVDGGECLVIVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIA1</accession>
    <name>E3QIA1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_05860</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family. Isoflavone reductase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094736.1">
        <property type="nucleotide sequence ID" value="XM_008096545.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIA1"/>
    <dbReference type="STRING" id="645133.E3QIA1"/>
    <dbReference type="GeneID" id="24411225"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05860"/>
    <dbReference type="eggNOG" id="ENOG502SHNB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044876_3_2_1"/>
    <dbReference type="OrthoDB" id="9974981at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05259">
        <property type="entry name" value="PCBER_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045312">
        <property type="entry name" value="PCBER-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF1">
        <property type="entry name" value="CIPA-LIKE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="4">
        <location>
            <begin position="12"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ30716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="302" mass="32279" checksum="FB0C70ACF79D21A6" modified="2011-01-11" version="1">MSTFINVALLGKGYLGSAILTELANAGFNVTVLGRSNSAKEGLPAGVRFEAVDYASIDSLAPALQDQDVVVSTVNKGGMLTQPTVIDACIKAGVKRYIPSDWGSFTTDPKAHSELAAVLGPMFDTQKYVIEKARAGEIEYTIFSIGCFTDYLVHLPMAFDFANKSAELFDDGKHSFSSTSIAGIGKAIVGALKNPGATKNRNLKIHELVVSQAQLLALAKKHSPPGAQWTETKLDGKAEFDKVLKAALKDASNEHKILQVIKTAVLGGRYASVYDEVDNELVGLPLLTDKDLEARMTAAFSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIP3</accession>
    <name>E3QIP3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_05797</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094673.1">
        <property type="nucleotide sequence ID" value="XM_008096482.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIP3"/>
    <dbReference type="GeneID" id="24411162"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05797"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_13_1"/>
    <dbReference type="OrthoDB" id="6133115at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000117">
        <property type="entry name" value="MFS hexose transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF29">
        <property type="entry name" value="SUGAR TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14500)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="133"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="168"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="289"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="331"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="355"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="393"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="430"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="460"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="41"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ30653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="541" mass="60772" checksum="D5C7A5E5A173F284" modified="2011-01-11" version="1">MVQIKRVQETGAADPILTRISEEDKVPWYQKPNLRYLYFMLFPTCMGIELTSGFDSQMINALQIVPSWVEYFGNPQGSLKGIIAAAYSLGAILSLPFIPVVNDKFGRRWSILGGSLVMVVGALIQGFSQHVGMYIVARMILGFGIPTCIVSASSLIGELSYPKERPVLTSLFNVSYYVGQILAAGICFGTNNIKSDWGWRIPSLLQICPSLLQITFVMFIPESPRWLITKDRSEEANEILIKYHAEGDRESEFVKAEMVQIKSVITLEMEAAKQTWMDLLNTAGMRRRALISMMLGLFTQWSGNTLISYYLGDLLQMVGLTDSAVKQKINLGLSGWALVCGLTVALLVRRIRRRVMYLVCTISLLFCYIAWTISMERAVHADENGYKNQGASVATIFFIFMYSPCYNIGYNALTYTYLIELWPYALRSRGLSLFQLFGRLAAFFTTFVNPIGLEAVSWRYLISYCCWLAFEVVFVYFMFPETAGRTLEELAFLFEDKALADQAVIAVEKAIHHEDMDPIGETKSGAVRAEAVEDVGAKSKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJ37</accession>
    <name>E3QJ37_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA polymerase kappa</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_06019</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094895.1">
        <property type="nucleotide sequence ID" value="XM_008096704.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJ37"/>
    <dbReference type="STRING" id="645133.E3QJ37"/>
    <dbReference type="GeneID" id="24411384"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06019"/>
    <dbReference type="eggNOG" id="KOG2094">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012348_11_2_1"/>
    <dbReference type="OrthoDB" id="1747274at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070987">
        <property type="term" value="P:error-free translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03586">
        <property type="entry name" value="PolY_Pol_IV_kappa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.810:FF:000003">
        <property type="entry name" value="DNA polymerase kappa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.270:FF:000014">
        <property type="entry name" value="DNA polymerase kappa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.100:FF:000010">
        <property type="entry name" value="DNA-directed polymerase kappa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1170.60:FF:000012">
        <property type="entry name" value="Putative DNA-directed polymerase kappa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.100">
        <property type="entry name" value="DNA polymerase, Y-family, little finger domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036775">
        <property type="entry name" value="DNA_pol_Y-fam_lit_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017961">
        <property type="entry name" value="DNA_pol_Y-fam_little_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050116">
        <property type="entry name" value="DNA_polymerase-Y"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022880">
        <property type="entry name" value="DNApol_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006642">
        <property type="entry name" value="Rad18_UBZ4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001126">
        <property type="entry name" value="UmuC"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002677">
        <property type="entry name" value="PRK02406.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11076:SF33">
        <property type="entry name" value="DNA POLYMERASE KAPPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11076">
        <property type="entry name" value="DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00817">
        <property type="entry name" value="IMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11799">
        <property type="entry name" value="IMS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00734">
        <property type="entry name" value="ZnF_Rad18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100879">
        <property type="entry name" value="Lesion bypass DNA polymerase (Y-family), little finger domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50173">
        <property type="entry name" value="UMUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UmuC" evidence="11">
        <location>
            <begin position="115"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="470"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="588"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="69"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="516"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="603"/>
            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ30875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="635" mass="72061" checksum="38625D83F7281D3A" modified="2011-01-11" version="1">MTTPPSPLPIDDLSEDAKVTLDNRTLKYALLGPSLTKAGQDAVDQSKVSEIIYNASKGSKFFNREEERDKILTNKIEQIINKKRDLEKQDLSRELRLADQLITQLELSRDLTQYIVHVDCDAFYAAVELLDRPELKDVPFAVGGGVLTTCNYVARKYGCRSGMAGFVAKKLCPELVMLKLNFEKYTAKAHEVREVFVEYDPRFESASIDEAYLNITEYCTDKGIGPAEAVEQMRREIYEKTKITVSAGIAANAKLAKICSNMNKPNGQFILPNDRSEILRFMAKLPPRKVNGVGRVLERQLAEIGIKTCADLYPQRQFLRPLFGEKAYEFLINVYLGLGRTRIQPAEEYERKSVGTESTFRDMSDPQQLREKLKWTAGELEKDMKRAEVKGRTLVLKAKLHTYEVLTRQVVLPRAIFLADDLYHFALPILAKLQEEMPGMTLRLMGLRCTHLVSTKKPDTMAFFGFRSRRSESGTSPVKPSKDNVNAGVDSGLNDDGWEQWPREELPGLDDDQDFDAFKEPANHDDDKLSPVRRHGKEIQPNPVREYAPVNDEMWDCPICNRPQAPDERHFNEHIDFCLSRQTIREAVHGDVPGPAPRSTTPDMKKPKVGGEKKRGRPPARQPSDDPRQKKLCFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJ42</accession>
    <name>E3QJ42_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fumarylacetoacetate hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_06024</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAH family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094900.1">
        <property type="nucleotide sequence ID" value="XM_008096709.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJ42"/>
    <dbReference type="STRING" id="645133.E3QJ42"/>
    <dbReference type="GeneID" id="24411389"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06024"/>
    <dbReference type="eggNOG" id="KOG1535">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028458_2_1_1"/>
    <dbReference type="OrthoDB" id="411064at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018773">
        <property type="term" value="F:acetylpyruvate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050163">
        <property type="term" value="F:oxaloacetate tautomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006107">
        <property type="term" value="P:oxaloacetate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.850.10:FF:000002">
        <property type="entry name" value="2-hydroxyhepta-2,4-diene-1,7-dioate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="entry name" value="Fumarylacetoacetase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11820">
        <property type="entry name" value="ACYLPYRUVASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11820:SF7">
        <property type="entry name" value="ACYLPYRUVASE FAHD1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="FAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumarylacetoacetase-like C-terminal" evidence="3">
        <location>
            <begin position="83"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ30880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="302" mass="32272" checksum="539C76D2B909BCD4" modified="2011-01-11" version="1">MSSELQSSFGRLLRFVPRSDPNKILIGEPESDSVDVGVAVRNGEEVKVVVWSGSSVLKPGSKTDECAIIDRILSPVSVDEIGTIRCIGLNYVQHAKEVGVALPDVPTVFLKPNTALGDPWPAPTVLPLLTQADDCGDYESELAVVLGKTAKNVSEADAMDYVLGYTACNDVSSRTYQLNQSQWCFAKGFDGSCPLGPTLVSKDLIPDPAKLHMRGLKNGDVLQESGIDDLIFNVPRVISFLSQSTTLPAGTVIITGTPAGVGLGRKPKVTLKDGDEFRVEILPHIGTLINVFQNESATTVGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJ77</accession>
    <name>E3QJ77_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">TBC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_06059</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ30915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094935.1">
        <property type="nucleotide sequence ID" value="XM_008096744.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJ77"/>
    <dbReference type="STRING" id="645133.E3QJ77"/>
    <dbReference type="GeneID" id="24411424"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06059"/>
    <dbReference type="eggNOG" id="KOG4436">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005062_1_0_1"/>
    <dbReference type="OrthoDB" id="159449at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.750:FF:000003">
        <property type="entry name" value="GTPase activating protein (Evi5)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.80:FF:000027">
        <property type="entry name" value="GTPase activating protein (Evi5)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.270:FF:000001">
        <property type="entry name" value="TBC1 domain family member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.750">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF9">
        <property type="entry name" value="GTPASE ACTIVATING PROTEIN AND CENTROSOME-ASSOCIATED, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90257">
        <property type="entry name" value="Myosin rod fragments"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="5">
        <location>
            <begin position="254"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="590"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="706"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="749"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="829"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="977"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="635"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="919"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="80"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="103"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="122"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="140"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="590"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="749"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="870"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="894"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="977"/>
            <end position="999"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ30915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1007" mass="110593" checksum="BC768663A26380D1" modified="2011-01-11" version="1">MVTVRLSEPPVLTVNTSAGPDSLPRRRPSTVRVEKLPHPVQEVEEAEVKDTPDTDADDSLPSDPATPLPDTTANKNLQDELVDCEEVDEVEEDQVISVQAQGSREEPRRRTITEQQRQETGEVAEEKEEEDDDEEVNWDELQKSEANEPRDADTDRSTAMLLAMLEQENDKLATNPKSIKVQAVEQVAASNRPRPPSMAQLRHMVHGPTPPALRYSMLPPPPMTDLEFYAALVKDYQQTAARLPTLLSNKIRKGIPPPLRGVVWQSMSGARDSSLEEQYDRFSGESSPYEPIIGKDLGRSFPGVDMFRDPEGEGQRMLGKVLKCFSLYDTKIGYCQGLAFLVGPLLMHMPDKQAFCVLVRLMERYDLRSCFLPDLSGLHVRIHQFRELLREHMTPVSNHLEDLQVDPAYVSQWFLSFFAVTCPLPMLFRIYDVIFAEGAPETLMRVALSLMQKNQTRILACTELEDVMQLLLSRGLWDCYHYNADEFVQDFVSLSGVVTREKLLQLEQGYRDAQIASANAARSSDVTTAASRFLGRIWASSTIISPKSSSTLSPGLTAPSRPLSMLRRTTSKQSLASTLNSMEASSVSVLSSASTEATTVSRDSSNTDDNSSIRESTPIPGGKPLYGTGGKNNKENALHTQIEDLLTALTELQRNHAQLASELQQEREQREEDKQAVRSLLDGLRKKASNDSVSTDASVDTVTAADDSAAEAREGGQGDVSTPPKTDEQGSPLPEDLSQLLDAVEERFGRHGSGDRRMSRGGSTAQMQQELQQLKDQLASAISQSQDYNRKILDLDQEISALKDQVRESHSHTRILHQDKQRLEKQIHNMRARASAAEADSNTHQGSDGLIRKSSTSGASGLRELKLSRSKSTPSQAGSTFNKRSSSLPKPHDSTPPPATQTRPPPPTDDQHEALLLELVQAKTAEAIARQEAEETKQKLESLRKAYGLASAETPPPATGSAAAAAAMGVLGRLTGAATEPAKPAPPATNTAATATTAAGGFWGWRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJB3</accession>
    <name>E3QJB3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">OPT oligopeptide transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_06095</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ30951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094971.1">
        <property type="nucleotide sequence ID" value="XM_008096780.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJB3"/>
    <dbReference type="GeneID" id="24411460"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06095"/>
    <dbReference type="eggNOG" id="KOG2262">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004965_4_1_1"/>
    <dbReference type="OrthoDB" id="9986677at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00727">
        <property type="entry name" value="ISP4_OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="304"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="429"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="469"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="506"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="536"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="610"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="714"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="741"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="823"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="894"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="934"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="975"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="37"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="229"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="48"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="86"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="149"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="177"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ30951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1034" mass="114137" checksum="0D773117330D2C1F" modified="2011-01-11" version="1">MSLRKAPGHKSKPAASFPPDPDADTVALALEPLPLLAPVAGSTNDSPAAAAAAAEAEADAANPWTPSSSDQIAFDPYNTTHHPRSRPSTLRSRPSALSYTSTAGEHGDDTTDTTPTSPAPQLDDGPMPSKPSLLRSARNDAPSYGAVSQDPSRNVSPTGSDPRTGNAHPLRYVSDTSKSASSRYSGASRRETSRLSEDLDATALATGLEGRFGVTQAPVTTNMLEDAKSDAAEDEAEYDDYTGSEPDEDPVDDSPHEVIRASVPPTDNITLSINTPRMWALSFLFSVLGSSTNLFFSLRYPSVAITPVIALLLVHPLGLMWDYALKRRDDPPEEFLDGVLLAGGADGRSPPKWYLARLRRWLAQGRWNEKEHTCVYVSSNVSFGFAFATDVIVEQSKFYHQEATIPYQVLLTLSTQTLGYAFAGLTRRFLVRPSGMIWPGTLMSAAMFGTLHKEENRIADGWRISRWKFFYLVWFGGFAFYFLPGLLMPCLSYFNVITWLAPKNVVVANLFGVVSGLGLFPLTFDWAQITYIGSPLLVPFWAAVNVIGGLVIVMWIIAPIAYYANVFYSSYMPILSSAVFDNKGQVYDVSKILTSDFLFDREAYSKYSRVFLPITYVLSYGVQFAALAALLTHTACWHGKDMWQTWKTALAEARNEGQAVYKPVAANSEYVTPRPSFSSSSRGISTPTSNLEEGMMFREDVHCRLMKRYKDAPLSWYLTTFVTMLAVGIFVVEYYPIHLPWYGLLMSLGICAIFFIPNGIVMAVTNQHSSIYLICQLICGAVFPGRPIANMVFVTYGYISSAQGIKFASDLKLGHYMKIPPRIMFSVQMVATIVSSLTQIGVLNWMFANVKGICTSEAVNGFTCPIARVHFNGSILWGVVGPGEFFGPNATYRGLVWCFLIGAIAPIPLWLYARKKKHSIVRKINLPVVFGSMAWIPPATGLNFSVWAVVCYVFNYLVKRRKSAWWAKYTMTMSAALDSSLAFGIVVIFFGFIYPGHMKGFKWWGTEVYKQGCDWQACSYNTVPEGGHFGPDSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJH9</accession>
    <name>E3QJH9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_06161</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ31017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095037.1">
        <property type="nucleotide sequence ID" value="XM_008096846.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJH9"/>
    <dbReference type="GeneID" id="24411526"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06161"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_28_4_1"/>
    <dbReference type="OrthoDB" id="440755at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718:SF9">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="201"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="230"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="263"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="289"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="319"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="351"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="382"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="421"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="460"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="485"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="523"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="555"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="587"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="165"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ31017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="623" mass="66504" checksum="D1623E05E5D7B45D" modified="2011-01-11" version="1">MAREKSSYDRPISVDMDRESLSRRASALEEVPTFVPPPGYPGIPVTRRVSTVSQSSRVMLENDDADDLEELVRNTSAVSKQRSRERRESHDNVFELPSFPRAAKPGPVSTIREVPSEFTTPQSTRPPSPVSGLVSGPQLPVEYETGTGQAYPDIGTIASFRGAIVLLCTCGAQLIDNVFMTGVNIALPAIQKDFEVKNGELQWLISAYTLTFGGFLLLAGVLADRFGRKLIFCSGMATLSVWTVANGFATSFIQLAIFRALQGIGAAMTVPSAVGIISNYFVTGDRTLGLTIFGAAGAVGFCLGLIFGGFLTSSLGWRYIFYIPTAVSGALGAIGWIFLPKDRIEGNSKPKLDFVGAGLSTAGLILLSFVLSSGGEYGWGKAFIIVLLVLSIALIVAFTYVEKKVSNPIMPLSLWKLQNFAALWIGGFVMYGGYQTTVYYTTLIAQEVNKLSAGETALRFLPMGATGFIFSLSMSRMLEVFNTKYLLILGMTICAIAPIPSALMKQDDLNFWKHVFPTTVMGVAGTTIVYCTITVVLLASLPVNVKSLCGGMINTAFQIGSGVGLALASAIVQAVDISKGHSQLQQFNTGLWCCVGLASVGVVASTFGVKNVGKVISGPAIAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKT4</accession>
    <name>E3QKT4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FAM86A protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_06616</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697355">
        <property type="protein sequence ID" value="EFQ31472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095492.1">
        <property type="nucleotide sequence ID" value="XM_008097301.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKT4"/>
    <dbReference type="STRING" id="645133.E3QKT4"/>
    <dbReference type="GeneID" id="24411981"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06616"/>
    <dbReference type="eggNOG" id="KOG2497">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038942_1_2_1"/>
    <dbReference type="OrthoDB" id="194386at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF130">
        <property type="entry name" value="PROTEIN-LYSINE N-METHYLTRANSFERASE EEF2KMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ31472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="359" mass="39990" checksum="DF1B7026C17F7816" modified="2011-01-11" version="1">MANSIPMTDSVERFCHQYLQLETTLDYPTAEVIREQQAQDTIYKNLFSDEGPRYSPPARYRVKVLKELVARIESSIEDWDQHEVSEDLMAALSESLATPIPSEISSAQQKAYVTYHMSSLAQYPSETHLHGPDITLLESRSLISASGTTGLRTWEAALHLGQYLCANRQIIQGKRVLELGAGTGYLAILCAKHLAATHVVASDGSDDVINNLPESFFLNDMQESSLVRRMELKWGHAMVGTEDQQWNNGETVDVVIGADITYDQSVIPALIATLHELFSLFPGVEVLISATQRNEATFEAFCSRCRQRGMGLRYVDFPIPVRERQTGPFYSDSVPIRICRVSAPSSTGVTWQDGWVGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKT9</accession>
    <name>E3QKT9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_06621</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697355">
        <property type="protein sequence ID" value="EFQ31477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095497.1">
        <property type="nucleotide sequence ID" value="XM_008097306.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKT9"/>
    <dbReference type="STRING" id="645133.E3QKT9"/>
    <dbReference type="GeneID" id="24411986"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06621"/>
    <dbReference type="eggNOG" id="KOG0569">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_5_1"/>
    <dbReference type="OrthoDB" id="4540492at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015149">
        <property type="term" value="F:hexose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045263">
        <property type="entry name" value="GLUT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503:SF8">
        <property type="entry name" value="FACILITATED GLUCOSE TRANSPORTER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="306"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="336"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="371"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="396"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="441"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="465"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="20"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ31477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="508" mass="54244" checksum="FA188D9B8DD63606" modified="2011-01-11" version="1">MAPSGFRQCMRHVSLYLIVLILVSTLGPLQFGFHLAELNAPQDVLTCRKKSIASKSIMLKWVHAKSPDTDSWLPDCIPMTDAVFATVSSIFTVGGLVGALCAGPFSSKRGRRPAMRITAIFFVIGAVIETLAGGAPALAIGRFFTGAAGGASTVIVPLYISEIAPPKERGLFGAMTQVSINVGILTVQTLGFFLSYGRAWRWILAAGVFAALGQAFGLLLIPESPAWLAANGDIPRARRTLQRIRGKDFDIREEVKDWDGETNAEQEGLLAQADDAPPVSPALSKHSSPVHLGFFQVIKDPVTRPAIAAVVGIMFAQQLCGINSIIMYSVSLLTDLLPVSSALLTILISVVNLITTAACSPLPDKLGRKRCILISIIGQGISSFILALSIRLGAKILSAVSVVTFVAFFAVGLGPVPFILASELVGQEAVGATQSWSLGSNYIATFLVAQFFPITNNALNHWLGGAGWVYFLFAGFALLFAIFVSVKVPETKGKKDADEVWGRARRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QL31</accession>
    <name>E3QL31_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_06858</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697356">
        <property type="protein sequence ID" value="EFQ31569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095589.1">
        <property type="nucleotide sequence ID" value="XM_008097398.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QL31"/>
    <dbReference type="STRING" id="645133.E3QL31"/>
    <dbReference type="GeneID" id="24412223"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06858"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_8_4_1"/>
    <dbReference type="OrthoDB" id="440553at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF51">
        <property type="entry name" value="QUINIDINE RESISTANCE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="346"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="38"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="16"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ31569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="392" mass="41697" checksum="2F0DFE43BC05589F" modified="2011-01-11" version="1">MAEPKTESQYAGAGDPPVPASAPAPGPEPLSVPIGDAAAPVEPYSVFTRTEKWFIIGMVAVAGFYRHAPLPTNIYLPAIPRLSEAFGRSVDDIKPDPLMLWGPLSDRHGRRPVFLVCLAVLNGACVGIAVIPTDAFWLLIVLRRLQAAGCASAIALGAGVIGDISTPDERGGFFGMFNIGPMFSPCIAPAVGGALADKLGWRSIFWFQVIMAVCCLLFILLFLPETLRSLVGNGNVSPGGVPSINPFVILVYPDVAITLVFTGVVCAVNDTVVTTVASSFARVYPWLSETVLGLCYLPTGLGMVFGGTLTGKFLDWDDARIRRRVEAEGGEGGSVLFPKEYARLRTMPVLLVLFSGAVIAWGFCVDRGVHIAVPLVLQVVYKKLCSDGVCKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLZ9</accession>
    <name>E3QLZ9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">OPT oligopeptide transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_07031</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095907.1">
        <property type="nucleotide sequence ID" value="XM_008097716.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLZ9"/>
    <dbReference type="GeneID" id="24412396"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07031"/>
    <dbReference type="eggNOG" id="KOG2262">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004965_1_0_1"/>
    <dbReference type="OrthoDB" id="9986677at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00727">
        <property type="entry name" value="ISP4_OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="146"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="253"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="318"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="355"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="391"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="460"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="529"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="555"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="638"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="708"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="750"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="784"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="814"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ31887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="879" mass="99103" checksum="20B2AA4A987D0E31" modified="2011-01-11" version="1">MSGNVESVRKGPSPARDEDIEKIPAQVNHSPEQKISDQISHEKLEELAPNGEGDYILEKINGMSEEEALEIVEEAVEFFKDDWNFPTDMRSRMKRLLEGPKAYGEHYDRDLRIDAVMIRYSSPYPGVRAVAEILDDQNVPIETFRAYFLGIGWAVIGTFISTFFNSRFPSISLSGQVIQILLFPCAKFLEFVLPDWGVTVFGTRHSLNPGPWNFKEQMFATITYNIAIYTTNSYGMILVQKSPVYYGLHFVNFGYQLMLTLFVQLMGMGFAGYLRRFSVYPVKALWPTILPTIAMNRALTRPEPKENINGWTISRYKFFYVCTICMFFYYWFPGYLFTALATFNWMTWISPENVTLAIITGSSLGLGLFNPVTTFDWNVATSSYAALAQPFFATCTQYFGSIIGGAIILGIYYTNMYNTAYLPINSSSPFANDGTPYVVQKVVVNNQLNETLYQQYSPPFYSAGYLLTVGANYCFYPVYFLYIMGNQWKTISAAYVDFYKGLRHGKGNYEGAMDVHNRLMAHYGEVPDWWFLVILVAAIVVSVVFLNIYPLDTPVWMVFLMIGINLVFAVPLSFLSATTGTNLGLGSLIQVITGYMLPGNTNAFLFSQTLGSWALAGYGDNYVQDQKMAHYTKIAPRAVFRSQIGTIIITCFVAVATQNFIMENVKGLCTPTQVSRFTCANDGAPLYSNSLMWGLLGSERMFVSFYPILKWCFLIGTIIAIVFLVGQGYGPKYLPGVRENLRQKLSPRTFALLDKTLFPFVASLLWLNPILVIQGVQHWAPSNLSYKTPGFILGYIFMYWLPRHRLAWWEKYNYVLSAALTAGVAVSALVMFFAVGYNPIALKWWGNTVSGAGVDGSQIGILPIPERGYFGPERGMFPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QME8</accession>
    <name>E3QME8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07180</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096056.1">
        <property type="nucleotide sequence ID" value="XM_008097865.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QME8"/>
    <dbReference type="STRING" id="645133.E3QME8"/>
    <dbReference type="GeneID" id="24412545"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07180"/>
    <dbReference type="eggNOG" id="ENOG502SNN0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099166_0_0_1"/>
    <dbReference type="OrthoDB" id="2150604at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="257" mass="28334" checksum="A2F42C6E50FD95A8" modified="2011-01-11" version="1">MPLLGSRQEVGGTGIRPTFGSFQDKSGDVASFVSNIFRGGLFSPPTLTYDPLLLLLNHDEESERDRLTEKWKDNKLQELNFVGVVAALLANVLTSTGSWPNLLPPETTTPWTVRTCWFCGIAFSLASVLTAADQTIRLHRMAGHRDGLILIRQSLRTKDRVLIGTEWKYQPRKMQVYVWQLAVLLLSGSVLCMMLGMVFLVWSAVIEDVVRGVGFGDNGKVAVIFTVVALATAIIFIVGQATLYHPVPKGSDIEEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMH7</accession>
    <name>E3QMH7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07209</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096085.1">
        <property type="nucleotide sequence ID" value="XM_008097894.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMH7"/>
    <dbReference type="STRING" id="645133.E3QMH7"/>
    <dbReference type="GeneID" id="24412574"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07209"/>
    <dbReference type="eggNOG" id="ENOG502SMAX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_516786_0_0_1"/>
    <dbReference type="OrthoDB" id="2975793at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF12">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="18"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="527" mass="58784" checksum="071D5C32583F158E" modified="2011-01-11" version="1">MTTANLPGFRQEGQLRIAGLSNTITDVIRLTGEMGIPYLWVDALCTIQEGDGGADKARQIPVMDAVYGLSELTIVQASGQDSKCPLLGFGDDSTPPRQTQGEIKPGLWVALQMTGFDDKQKASSTWNTRAWTSQEAVLSPRLLIFHHGHVTWECRERVWCEDMSTEPGDTPQPAKSSSFMPQFGSQMLPVGASELQEIHNELQSLESIDHLGRNDHISRYESAVQEYTSREMTYWGDKLNAFAGLGAIYERQMGTKLVFGLPANQLDMALLWTTTDGASLERLPDFPSWSWAGWKGAVHHPSSNPVALSPTCHFWIVDKDNRATDDGKMQLKRLVQAWEADDYVPHERPVRVRPIDPGNRTRYPKVGVSRCLDRSHTDHLDPKMDLSKCLCFETLHSNASHFSIKDGRKLVFNLTGKVVGGIALDEPLGAAGLTADMELARLNMCTIGQRNREEEYFPEFLFSTPGLGGNMVMEAKDSPARRSEPHMEWCRVLLVEKRADGSVKRRGIGDMMGAALYDLKQKMLFLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QML5</accession>
    <name>E3QML5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">cyclin-dependent kinase</fullName>
            <ecNumber evidence="1">2.7.11.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_07247</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="1"/>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096123.1">
        <property type="nucleotide sequence ID" value="XM_008097932.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QML5"/>
    <dbReference type="STRING" id="645133.E3QML5"/>
    <dbReference type="GeneID" id="24412612"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07247"/>
    <dbReference type="eggNOG" id="KOG0594">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_181_6_1"/>
    <dbReference type="OrthoDB" id="413582at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030332">
        <property type="term" value="F:cyclin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000082">
        <property type="term" value="P:G1/S transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010389">
        <property type="term" value="P:regulation of G2/M transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF576">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE CSK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="93"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ32103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="373" mass="41058" checksum="D2BEA6B0E486CD60" modified="2011-01-11" version="1">MADNDWRLQLSALDRYENIQKIKAVLEAAGSEAKATSQSHAFSVEDQAYKDSKSRAQYDEICQLVASANLTPQDAPAPGGDHGDDVGVTIGPYTSCVPFATGLTSEVYRCKDRALKVIVETHNIEPHNPHREAKILATLKRPCINLLETFRDQEQRLVLVFPYKPLTLADLIDKGTPPLARVKHIFKDILTALKDIHSEGIIHRDVKPEAILLDGLDGPAYLSDFGTAWHPAMSVVSEPPDGKILDIGTGPYRAPEALFGDKAYGPAVDMWAVGCMLAECCRSPPKPLFESRPAHEDGNQLGLILSIFKTLGTPTRETWPEAASFKTPPFDMYRMIDGNSWEEILPDVDVQVRGLVSSLVRFDSKRATAAQVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMM6</accession>
    <name>E3QMM6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">YDG/SRA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_07258</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096134.1">
        <property type="nucleotide sequence ID" value="XM_008097943.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMM6"/>
    <dbReference type="STRING" id="645133.E3QMM6"/>
    <dbReference type="GeneID" id="24412623"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07258"/>
    <dbReference type="eggNOG" id="ENOG502QRDQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033920_1_0_1"/>
    <dbReference type="OrthoDB" id="2270193at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044027">
        <property type="term" value="P:negative regulation of gene expression via chromosomal CpG island methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.280.10">
        <property type="entry name" value="SRA-YDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036987">
        <property type="entry name" value="SRA-YDG_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003105">
        <property type="entry name" value="SRA_YDG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045134">
        <property type="entry name" value="UHRF1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14140">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE UHRF-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14140:SF27">
        <property type="entry name" value="OS04G0289800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02182">
        <property type="entry name" value="SAD_SRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00466">
        <property type="entry name" value="SRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51015">
        <property type="entry name" value="YDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YDG" evidence="4">
        <location>
            <begin position="280"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="11"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ32114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="449" mass="49020" checksum="AC3A9449559104D2" modified="2011-01-11" version="1">MAEKTGCSMEKATKRGAEDEIELPAKRVHQDHPAGAIEEPKNQGNVLAHGGVVAESSTSITDSAKSGVQKTTGDAVKHNAKTIKIPVVSDDIAYLEHIRHKVIGTIGLLSKRSGPGSVPPSELLDRLDQFFNWLETRPWGPEYLPLSNRKTLETMLRFVWEPTEKRTQAYFSGEQKTRAKALTTNWGDKEASLFVDDDENDSQMPADATEDAEMITKTKPTKKPTKDSGLKIVDFRLPPLDHHIFGLTKPMCGIAYILGKTKVYHYNPQMAGLKKSSHAFGHNGIEPGAWWPMQAAAVFNGAHGSWQGGISGHAGEGAYSIVISGAYKGCDADQGNTLHYSGSGADVHTGQTPQNKDGTKLLHLSLKKGNPVRVLRSASGKGGAFRPSHGIRYDGLYKVTQVRILTKQKGGAYYQFELERLPGQKDLVELLGTPDNAQQAQWLAVREGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMN6</accession>
    <name>E3QMN6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07268</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096144.1">
        <property type="nucleotide sequence ID" value="XM_008097953.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMN6"/>
    <dbReference type="STRING" id="645133.E3QMN6"/>
    <dbReference type="GeneID" id="24412633"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07268"/>
    <dbReference type="eggNOG" id="ENOG502SFZQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056399_0_0_1"/>
    <dbReference type="OrthoDB" id="9997739at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="9"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="276" mass="32026" checksum="D8A82E761416928E" modified="2011-01-11" version="1">MTSSIFKSRQVTFLIGPNRVEFNVHQYAFTRLSAPLRAMLAEDAKESVEVGVIWDDVEPSTFTSLLEYAYTDNYSVPRLPRKKSVATAAVVLPNQADQGDAIDEEDWWSVSSIMTWMMDNDDRFGDCTRFGKWCYGRKYFDTDFPGPQPYWHDELQRSDCTGLATIFMLHVKLYALADRYRFMSLRALCLQRLRESLVNVVLRTEFCETLVEMLAFAYANTPPGDDLRMMLLRYCIFQMNHLKRHGYLYQLVLEMPPQFAAELLLEVPQGLWESAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>E3QN79</accession>
    <name>E3QN79_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="6">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_07461</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase C19 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="6"/>
    <dbReference type="EMBL" id="GG697361">
        <property type="protein sequence ID" value="EFQ32317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096337.1">
        <property type="nucleotide sequence ID" value="XM_008098146.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QN79"/>
    <dbReference type="STRING" id="645133.E3QN79"/>
    <dbReference type="GeneID" id="24412826"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07461"/>
    <dbReference type="eggNOG" id="KOG1871">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008279_3_0_1"/>
    <dbReference type="OrthoDB" id="429671at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02257">
        <property type="entry name" value="Peptidase_C19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF687">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="3 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="8">
        <location>
            <begin position="501"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="119"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="196"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="854"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="39"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="134"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="232"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="326"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="356"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="375"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="396"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="856"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="904"/>
            <end position="913"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ32317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="947" mass="101543" checksum="899C6954D080D68F" modified="2011-01-11" version="1">MNNRHLPAGQAMPGGGGPVGAGGVDMGGGPGGGNRRRMQQQPTYAQYQQQQYQQHMPMYPNYMNPYAAAPYYHQLPHQYQNGGIPSGYMHYQQQQQPYVRSPQAMPQYVPMAGVSVLQPYTQPPQPSPALSTPYQPPPVPTAMPVQSPPPPPPPPQPIEPTPEPPVITPPVVASSVVSSSAVTPFAEPFYASVTATPAPVSVPQSPELPKQDKDFRAPLPWTPPGQAPFPRRAPKSRRRRRLMSANAQDLTLPVEQHEGALESNATVGELSAKAGATEARDAIDGSAPKADSKKTVFWNPKDTDSESATLRADSLASETPKESDRSATSVSNAGSPKANVSETPSARPTTSSSNISASRPAVPVIPVVPVLPKSSPKESKPSEEPKQPAAQDVKSAETTETTDAAAVGQEKTDAQQAAPIKAAPKTWSGLFSAAAAAAAKAQLNANGSGTPAATNGAAINGDGSVNGSASSFSTGNANSLVAAIQDFRVGNPAKVQFIEPRGLINTGNMCYMNSVLQVLLFCAPFYNFLDQVSKRAVHKFKSDTPVIDAMIMFMREFRVIDATDSVEKLRRKLKSEQLEQYGESFIPEFVYKAIQPLPAFASMRRGHQQDAQEFLGLILNAIDEECAQVMSAGGVSNGLAEARPTSSAASVVESNDGADGWFEVGSRQRAVETRSSGASSTTPITRLFSGQYRSELRRPGVKDSVTTEPFQSLQLDIGAPHIHNVVDAIKGLTVPERLQGDAAPMTKQTLIETLPPILILHLKRFKFDTEGTTKIAKKVGYPLDLQLPAEVLSKRRRNALVAEGAPMPKYRLIGVVYHHGKQANGGHYTVDVRRQDDNEWIRLDDTVIRRVRSEDVAEGGAEEDVKEAGRSGPASRDASTNRFGAMADEDEGEGWKEVTTSAKGGDKSGEKKWSAVANGNGSAPKGKAVKDNIKDNKVAYLLFYQRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QN83</accession>
    <name>E3QN83_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Dihydrofolate synthetase</fullName>
            <ecNumber evidence="7">6.3.2.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_07465</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>7,8-dihydropteroate + L-glutamate + ATP = 7,8-dihydrofolate + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23584"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17839"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57451"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.12"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cofactor biosynthesis; tetrahydrofolylpolyglutamate biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the folylpolyglutamate synthase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.12" evidence="7"/>
    <dbReference type="EMBL" id="GG697361">
        <property type="protein sequence ID" value="EFQ32321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096341.1">
        <property type="nucleotide sequence ID" value="XM_008098150.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QN83"/>
    <dbReference type="STRING" id="645133.E3QN83"/>
    <dbReference type="GeneID" id="24412830"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07465"/>
    <dbReference type="eggNOG" id="KOG2525">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015869_1_1_1"/>
    <dbReference type="OrthoDB" id="5212574at2759"/>
    <dbReference type="UniPathway" id="UPA00850"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008841">
        <property type="term" value="F:dihydrofolate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004326">
        <property type="term" value="F:tetrahydrofolylpolyglutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="entry name" value="Mur ligase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="entry name" value="Mur-like, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001645">
        <property type="entry name" value="Folylpolyglutamate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01499">
        <property type="entry name" value="folC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136:SF0">
        <property type="entry name" value="DIHYDROFOLATE SYNTHETASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136">
        <property type="entry name" value="FOLYLPOLYGLUTAMATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001563">
        <property type="entry name" value="Folylpolyglu_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="MurD-like peptide ligases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="MurD-like peptide ligases, peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR001563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ32321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="415" mass="45036" checksum="994CF9EF0F7DA806" modified="2011-01-11" version="1">MAMKGISLGLHRISRALEGVPQKWDAIHVAGTNGKGTTCTYLAALCRSFGISNGLFTSPYLVEPRDAIKINGVPVQQDVYSDVRRKILDDEQTRLAQDASQEALTIFEVTTLIAFGVFSRADVQMGLVEVGLGGRLDSTNALRRKRVTVITKIGLDHQAFLGNTLPEIAKEKAGIMMAGVPCVVDGSNPPEVLEVFRQHAVSVSAPLHLTTYQNGLLETLYQSELMPHQAQNMACAITAFQIAYPHLNLSVEKALPILKDVTHLGRLSWLEVGEKYPSRKGKPILIDGAHNPQSAETLSAFIERRVRDADKPVTWVVSVSKQDGKDAGGMLRTLLRPGDSITCVPFSKRETMPWVEPLPLDTLREMASNAGAKDIFLAEGGLEAATQWAVDIAGDGPIVLTGSLYLVGDAYRVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNU5</accession>
    <name>E3QNU5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Citrate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_07547</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the methylcitrate cycle that catalyzes the synthesis of (2S,3S)-2-methylcitrate from propionyl-CoA and oxaloacetate. Plays an important role in detoxification of propionyl-CoA, an inhibitor of both primary and secondary metabolism. Also has citrate synthase activity using as substrates acetyl-CoA and oxaloacetate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>oxaloacetate + acetyl-CoA + H2O = citrate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16845"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>propanoyl-CoA + oxaloacetate + H2O = (2S,3S)-2-methylcitrate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23780"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57392"/>
            <dbReference type="ChEBI" id="CHEBI:58853"/>
            <dbReference type="EC" id="2.3.3.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Organic acid metabolism; propanoate degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the citrate synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697363">
        <property type="protein sequence ID" value="EFQ32533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096553.1">
        <property type="nucleotide sequence ID" value="XM_008098362.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNU5"/>
    <dbReference type="STRING" id="645133.E3QNU5"/>
    <dbReference type="GeneID" id="24412912"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07547"/>
    <dbReference type="eggNOG" id="KOG2617">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022049_2_1_1"/>
    <dbReference type="OrthoDB" id="8017587at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050440">
        <property type="term" value="F:2-methylcitrate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036440">
        <property type="term" value="F:citrate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019629">
        <property type="term" value="P:propionate catabolic process, 2-methylcitrate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.230.10:FF:000001">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.580.10:FF:000001">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="entry name" value="Citrate Synthase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="entry name" value="Cytochrome P450-Terp, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019810">
        <property type="entry name" value="Citrate_synthase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007128">
        <property type="entry name" value="PRK09569.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739">
        <property type="entry name" value="CITRATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739:SF15">
        <property type="entry name" value="CITRATE SYNTHASE 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00143">
        <property type="entry name" value="CITRTSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00480">
        <property type="entry name" value="CITRATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00056526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ32533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="473" mass="52274" checksum="CEFB2AD1DE82BBB5" modified="2011-01-11" version="1">MTLNFTRSTRAVGALRCLAARSSLNARKYSSSSEPDLKTTLKSVIPAKRELLKKVKAHSSKVIGEVKIENAIGGMRGLKAMVWEGSVLDANEGIRFHGKTIKDCQKELPKGKTGTEMLPEAMFWLLLTGQVPSTNQVRQFSRELAEQAQLPQFVNKLLDDFPKDLHPMTQFAIAVSALNYTSKFAKAYEQGLNKADYWEPTFDDSISLLAKLPTIAAKIYQNSYRGGGALPAEVDIEQDWSYNFAAMLGKGGKENESFQDLLRLYLALHGDHEGGNVSAHATHLVGSALSDPFLSYSAGLQGLAGPLHGLAAQEVLRWIIQMKDNIPKSYTDKDVTDYLWTTLNSGRVVPGYGHAVLRKPDPRFEALMDYAAARPEIAQDPIFQLVQKNSRIAPEVLKKHGKTKNPYPNVDSSSGVLFHHYGFHETLYYTATFGVSRGLGPLAQLIWDRALGLPIERPKSINLESLLKQAESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QP70</accession>
    <name>E3QP70_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pal1 cell morphology protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07802</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697364">
        <property type="protein sequence ID" value="EFQ32658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096678.1">
        <property type="nucleotide sequence ID" value="XM_008098487.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QP70"/>
    <dbReference type="STRING" id="645133.E3QP70"/>
    <dbReference type="GeneID" id="24413167"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07802"/>
    <dbReference type="eggNOG" id="ENOG502S21G">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025891_0_0_1"/>
    <dbReference type="OrthoDB" id="5352132at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013226">
        <property type="entry name" value="Pal1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28307">
        <property type="entry name" value="PROTEIN PAL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28307:SF2">
        <property type="entry name" value="PROTEIN PAL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08316">
        <property type="entry name" value="Pal1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="282"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="426"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="436" mass="47120" checksum="D2564325168ABAF8" modified="2011-01-11" version="1">MAPTLDPKASPTAEELFDSLTIDDQKQSRPSGGPSSTNRPDQPGRRGPPPPGHRPSRSQEEAMRQRRLQGSNGGPPRPSGSQASPPRRPRERRPRRNSDSSVLIDVEKPLTEEEKKAKEARRRERERRAREGKDKDPKKPSRRLDIIDQLDATSIYGTGLFHHDGPFDAANPHRNRKGSRRAPMHAFAKDSLNMSLGGSGPLNKRPDHATFLGNNDGDASADYATAAARNAERKIDPAVFDPRSRGSIVYGEESLGLGASTFLEGTPAARAAIQRTQAEQAQQTAAEGLGRSKSIAQRIRGIKREPREYGPSGRITNPEGAYTSRRSPDGHGPATSVSYTGERNPFFSEYGKETETISVRRNDAKSPGTPPPVPRRGSANGLERRATSDVTSPTEEGPSKPSGGFLARVKSLKGGGRKRQASDVMVPPPPAPGTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQ41</accession>
    <name>E3QQ41_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08123</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697366">
        <property type="protein sequence ID" value="EFQ32979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096999.1">
        <property type="nucleotide sequence ID" value="XM_008098808.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQ41"/>
    <dbReference type="GeneID" id="24413488"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08123"/>
    <dbReference type="eggNOG" id="ENOG502T4DA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070612_0_0_1"/>
    <dbReference type="OrthoDB" id="4842829at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="251" mass="26727" checksum="E0614B7532C86C7C" modified="2011-01-11" version="1">MADAMIILETHIYSNTPNGLPPWVRSFHLRLSATGKKADILKLVHDSMVRLGRSDPVAETQITLYWTRHGRVVSIPGTSSSNAMITLPVYRPPQLFNFNVGHPMVYPQHSQTAMASAYPLALTYSGGANYLHSYGPNPVMMPPTMVPAQQTWMVGYVNVPFFGADRTGGIGGQPIVSDVVREARLDTLAEEGLAGMLEWATGPTGLKLILIVDVDGRGVISGYVGSPAAPVVPESPSPASPAPAASPNPGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQ49</accession>
    <name>E3QQ49_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">WD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_08131</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697366">
        <property type="protein sequence ID" value="EFQ32987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097007.1">
        <property type="nucleotide sequence ID" value="XM_008098816.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQ49"/>
    <dbReference type="STRING" id="645133.E3QQ49"/>
    <dbReference type="GeneID" id="24413496"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08131"/>
    <dbReference type="eggNOG" id="KOG0305">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014831_3_0_1"/>
    <dbReference type="OrthoDB" id="10263272at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010997">
        <property type="term" value="F:anaphase-promoting complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990757">
        <property type="term" value="F:ubiquitin ligase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905786">
        <property type="term" value="P:positive regulation of anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033010">
        <property type="entry name" value="Cdc20/Fizzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918">
        <property type="entry name" value="CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918:SF5">
        <property type="entry name" value="MEIOSIS-SPECIFIC APC_C ACTIVATOR PROTEIN AMA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="270"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="311"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ32987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="573" mass="62973" checksum="347E95C8941C1713" modified="2011-01-11" version="1">MHRYIPHRDAETPLSDKIRLKALPPPPSLLPSSRAIVTVGRPSILSTNTPEPPVKIKASGRRITTRFFGPRPREEEDQKRHEERLADALKIDQAARVLRIGLLQPSSTSSRSWPTLEAQTPPGCNLPSGPYRVLQAPELEDDYYRSPLAYSPTCGCLAVALGNTVYRWSEQHDPQPVYRAPRLRRNSLTSLSFSSTQGGKAILAFGRKDGFFVMKRPSQNPFNSGALVPTEDILVGDGQGGILHYMVEWPSLWEISRDTWFGKVTPIAKIAVHTSQICALVWSPNGQQFVSGSNDNTACYFEMSRTMEGPHKKRDSAVVRRSRRSMEHDGSFERGTLPADQSGVGPSQRESVETSLNAFPNSETIEVGVAENITRATQTSMQGLRLFGHGTEIHCWRHDAAIKAIAFCPWQEGLVATGGGLGDKCIHFFHAGTSTPLATIVVGAQVTSLIWSTTKREIAATFGYSHGYAQTEHPYRIVVFSWPSCRQISAVAWPGGPRALYAIPYPRGPADARKGSRTAREGTIVVASSDETLKFHEVWWDQPKMAIGGAQGILGSDILESLAGIDKEGDVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQX9</accession>
    <name>E3QQX9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Peroxisomal adenine nucleotide transporter 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_08411</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697369">
        <property type="protein sequence ID" value="EFQ33267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097287.1">
        <property type="nucleotide sequence ID" value="XM_008099096.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQX9"/>
    <dbReference type="STRING" id="645133.E3QQX9"/>
    <dbReference type="GeneID" id="24413776"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08411"/>
    <dbReference type="eggNOG" id="KOG0769">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_6_2_1"/>
    <dbReference type="OrthoDB" id="18574at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015217">
        <property type="term" value="F:ADP transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052217">
        <property type="entry name" value="Mito/Peroxisomal_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45939:SF2">
        <property type="entry name" value="CARRIER PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G13870)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45939">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PMP34-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="7"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="112"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="212"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="243"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ33267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="371" mass="40029" checksum="E39324234279A7D9" modified="2011-01-11" version="1">MAPVGVLEALGHALAGATGTALSTAAVYPLDLVTTRLKVQRHLRRENAISEKDQYRGVFHALKVISSQEGGISSLYTGIAQDVFKSIADSFLFFLFYQYFRDARRRSRGRRLPVMDELAIGALAGACARGCTTPIANVVARKQTSAMFEANTDDENASVWKILSSIGAENGIAGLWAGYSASLLLTINPSITFFLNEQLGKTLLPDSDETSHSTQTTFLLAAASKSIATIISYPLQTAKARLQMRGSGNASPHRSTSNSDTPSISESRKGPQSPISVNEMSGALSGLKKLVDDSVIAIVLSIARTEGILALYAGIQGEVLKSFFSHGLTMVSKGIIHKFVIRLGILLLSLSQGQSRRVKLQRLRQAFLRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQY8</accession>
    <name>E3QQY8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GH16 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_08420</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697369">
        <property type="protein sequence ID" value="EFQ33276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097296.1">
        <property type="nucleotide sequence ID" value="XM_008099105.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQY8"/>
    <dbReference type="STRING" id="645133.E3QQY8"/>
    <dbReference type="GeneID" id="24413785"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08420"/>
    <dbReference type="eggNOG" id="ENOG502QWBR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040566_0_0_1"/>
    <dbReference type="OrthoDB" id="25131at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00413">
        <property type="entry name" value="Glyco_hydrolase_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38121">
        <property type="entry name" value="GH16 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38121:SF5">
        <property type="entry name" value="GH16 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178747" description="GH16 domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="2">
        <location>
            <begin position="44"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ33276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="361" mass="39028" checksum="42D8D81489540159" modified="2011-01-11" version="1">MRSFAKACLLALPLLPDVTRAACECGFSANITGTVEVFTDLIETDFTKVMQIKNNTDWVRQEFNKTNTNARGPLGEDFQPANIAAVHEGSTSYGLSPTKADAGLQLLVGSSTVNGLVPGAEIDSARYDVQYGSFRAMMKLPGIAGTCAAFFWYHNDTQEIDMEFLTREFNPSNNSFPVNIVLQSRASLEKGYDASSTGNFLKVNLGFNPATDFHEYRIDYLRDKVTFYADGKVLGAMNGSAVPTEGGHLILQHWSNGNPLWSGGPPKTDAIMTVASVKAYFNSSLDARKADHGSRCIDPAAPGAVCAIPDNPAFFFGTQASMTNKQTASGTPSTKHSGSRMMNPPSWMLVSALLFLGVRFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRN3</accession>
    <name>E3QRN3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phenylalanine ammonia-lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_08800</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the PAL/histidase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697371">
        <property type="protein sequence ID" value="EFQ33521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097541.1">
        <property type="nucleotide sequence ID" value="XM_008099350.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRN3"/>
    <dbReference type="STRING" id="645133.E3QRN3"/>
    <dbReference type="GeneID" id="24414165"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08800"/>
    <dbReference type="eggNOG" id="KOG0222">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014801_3_1_1"/>
    <dbReference type="OrthoDB" id="10051290at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016841">
        <property type="term" value="F:ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00332">
        <property type="entry name" value="PAL-HAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.200.10">
        <property type="entry name" value="Fumarase/aspartase (Central domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="entry name" value="Fumarase/aspartase (N-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.20">
        <property type="entry name" value="Phenylalanine ammonia-lyase 1, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001106">
        <property type="entry name" value="Aromatic_Lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022313">
        <property type="entry name" value="Phe/His_NH3-lyase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005922">
        <property type="entry name" value="Phe_NH3-lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023144">
        <property type="entry name" value="Phe_NH3-lyase_shielding_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01226">
        <property type="entry name" value="phe_am_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10362">
        <property type="entry name" value="HISTIDINE AMMONIA-LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00221">
        <property type="entry name" value="Lyase_aromatic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="L-aspartase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00488">
        <property type="entry name" value="PAL_HISTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="696"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="708"/>
            <end position="724"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ33521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="724" mass="78132" checksum="CDFA39961C0DFD95" modified="2011-01-11" version="1">MAIPPVLALPHASSLRNDLNKLRTLQFSNAEVSLDGNNLDVATVVAVARHGLTPHVKDDPEIKRKVLQSTQVLDRYVENGWVVYGVNTGFGGSADSRTEQLKRLQISLLQHTQSAIIASTDLTQGQVDQDGQSHVIPSAWVKAAMVVRANQNLRGHSAVRIEVIQLLLTLLRHDIAPMVPLRGTISASGDLMPLSYIAGILIGDPGVLVAVGSGCNRKVMSACEALKRCDIQPVELQPKEGLGLINGTAPSAALASLVIHDANQLAVLAQALTAFTAECLIGNVEWANEFIHKIRPHVGQVEAARNIRSFLKSSDFVLGLETKRRTGHGLWQDRYSTRTAPQWIGPYLEDLMLAQHQIEVELNSTSDNPVIDVGTGGDSTAGDIYSGGNFQATAITSAMEKTRTALQMIGRMLFSQCSELINPATNNGLDSNLVFGDPGESYTMKGIDVNMSAYMAELAALAHPVSSHVQSAEMHNQGINSLAFLSGRRTMEAVDVLSHMCAAHLLVCCQAADLRDYYERFLSSISVIKIFNETDMGLDSAQLEKLTIGLDESIRAWWNEANKLGHAQRCSIVASKVTTHVMDFVMKEEIGGVSLKAVMGVQDEFCHSMEVWFKDITNNPKIIHSNSTATHVAYLEGLGQGSSLLFDLVRGKLGITFHQGLRQEQMSTIGNSVSRIYEAIREGVVVPALMPCLEGGEDKSLETGTGTPASSDASVGSAGVPGRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRZ4</accession>
    <name>E3QRZ4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_08561</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697372">
        <property type="protein sequence ID" value="EFQ33632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097652.1">
        <property type="nucleotide sequence ID" value="XM_008099461.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRZ4"/>
    <dbReference type="STRING" id="645133.E3QRZ4"/>
    <dbReference type="GeneID" id="24413926"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08561"/>
    <dbReference type="eggNOG" id="KOG1199">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_42_0_1"/>
    <dbReference type="OrthoDB" id="3819888at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43658:SF8">
        <property type="entry name" value="17-BETA-HYDROXYSTEROID DEHYDROGENASE 14-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43658">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="2">
        <location>
            <begin position="6"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ33632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="262" mass="27675" checksum="EFF2399EFAFF818C" modified="2011-01-11" version="1">MKIQGRTFIISGGASGLGQACVEEICKNGGNVAVLDMNEESGNELVSKLGSSAKFFICDVLDTNSIEAAVQGTAAWVKQTGKPLGGVIPAAGVGNPSTILDRNGNPFSLDDWDFVLNINLRGTIDLTRQALALMARNDPSPPDGERGVVVMVASSAAFDGQKGQVAYAASKGAVAAMTLPMTRDLARFGIRVVTIAPSLFESRMTAVMSDKVRASLERSMEFPVRAGKPDEFAALVRHAIENVMLNGTVLRLDGGMRMPSKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>E3QS29</accession>
    <name>E3QS29_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein disulfide-isomerase</fullName>
            <ecNumber evidence="3">5.3.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_08596</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Catalyzes the rearrangement of -S-S- bonds in proteins.</text>
            <dbReference type="EC" id="5.3.4.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="5.3.4.1" evidence="3"/>
    <dbReference type="EMBL" id="GG697372">
        <property type="protein sequence ID" value="EFQ33667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097687.1">
        <property type="nucleotide sequence ID" value="XM_008099496.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QS29"/>
    <dbReference type="STRING" id="645133.E3QS29"/>
    <dbReference type="GeneID" id="24413961"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08596"/>
    <dbReference type="eggNOG" id="KOG0191">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030577_0_0_1"/>
    <dbReference type="OrthoDB" id="10264505at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034976">
        <property type="term" value="P:response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03002">
        <property type="entry name" value="PDI_a_MPD1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02981">
        <property type="entry name" value="PDI_b_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041269">
        <property type="entry name" value="QSOX_Trx1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057305">
        <property type="entry name" value="Thioredox_PDIA6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45815">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45815:SF3">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18108">
        <property type="entry name" value="QSOX_Trx1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24541">
        <property type="entry name" value="Thioredox_PDIA6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005673324" description="protein disulfide-isomerase" evidence="8">
        <location>
            <begin position="23"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="9">
        <location>
            <begin position="11"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="240"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="445"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="250"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="274"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="293"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="453"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="465"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ33667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="483" mass="51496" checksum="136EF117E8CED1B0" modified="2011-01-11" version="1">MHHPTLLAAGAAVLSALPGAQAGMYPKSSAVLQVDAKNYDDLIAKSNYTSIVEFYAPWCGHCQNLKPAYEKAAKNLNGLAKVAAVDCDEEANKPLCGQFGVQGFPTLKIVKPGKKPGKPVVEDYQGPRTATGIVEAVVDKISNHVKRVTDKDIDSFVEGDRPKAILFTEKGTTSALLRSVAIDFLDAVTVGQVRSKESKAVEKFGVKSFPTLVLLPGGDKEPIVYDGEMKKDGLVSFISQVASPNPDPAPKGDKKKADKKTEKKAGKKAEKSEPASAQSSTSTAADEKATPKAETSNETPSAEQTAPAASAVPSLPVADTPEKLQAECLSAKSHTCILAFVPSKENEKAEKALTSLSELVHKYEQSHRKLFPFFSVPSDNTAASTVTKGLGLTGDVEIVAVNARRGWWRHYEGDFDVVSVESWIDAIRLGEGVKQTLPEGLVVEEVKTESAEESTASTAATEPVPKSETEAPKETPSDAHDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QS34</accession>
    <name>E3QS34_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Six-hairpin glycosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_08601</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697372">
        <property type="protein sequence ID" value="EFQ33672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097692.1">
        <property type="nucleotide sequence ID" value="XM_008099501.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QS34"/>
    <dbReference type="STRING" id="645133.E3QS34"/>
    <dbReference type="GeneID" id="24413966"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08601"/>
    <dbReference type="eggNOG" id="ENOG502SI0K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014083_0_0_1"/>
    <dbReference type="OrthoDB" id="4423297at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ33672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="702" mass="79398" checksum="330D39D1C3A912B9" modified="2011-01-11" version="1">MVRTIELYNDEFYVRMDRATGAVLEITDPRAKIPMNWISSPANAPWQPLGSRWGLGFADLGANLLHRLFWNSPQIDPSSSRDIMAVTYHAGPLELIVHRHLDGRKRCLTESYEFRNRGTYPLNLSSRGETSFAIYTPFNDHYTNTTDALHSRTHAHIWANGGSSAWVKLSQMGGRGRNLGLVLTKGSLSGYSIESRDEITHSNTRGVFLLHPSVPVLEPGQSNTIEWTLFWHSDWEDFFAQCARRSGQFIYFDIPRHTLVSGDAVKIRMRGSATAINSTTTVNGQSVEQEGSTFTFIHHAGDMGQKTLCIATGQDGEKNESYVFLNTVPRCDDLIESRIKFIVEKQQVKDVDDLLYGAYVVYDNQAEASPFYETHQDRNAGRERVGMGVLIGRWLKKKPDGKLRDSFTAYYSFVCTKLQAENGFVFDAPNGTGTYINKRLYNWPWVLQLHLVAAAIGIPALYDKSPITRFMETLENFYEEGGASLYAIGLPILESLRMLQALGMEVAYQRAKSLYISHGQNIVKRGTDYPPFEVNFEQSIVAPAAIILLELYRATGDKTWLAAAGLQMEVLLRFAGKQPDYRVHDVAIRHWDGHWFGKDRTWGDTFPHYWSTLNAIALHHFSISTGDLSYGKQSDGVLQANLSLFTPEGRASCAWIYPRSVNGRLAHYKDPYANDQDWALAHLLQIEDDTLWVEQHDTRLIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QS78</accession>
    <name>E3QS78_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_08961</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697373">
        <property type="protein sequence ID" value="EFQ33817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097837.1">
        <property type="nucleotide sequence ID" value="XM_008099646.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QS78"/>
    <dbReference type="STRING" id="645133.E3QS78"/>
    <dbReference type="GeneID" id="24414326"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08961"/>
    <dbReference type="eggNOG" id="ENOG502SHBV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042166_0_0_1"/>
    <dbReference type="OrthoDB" id="6361347at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037473">
        <property type="entry name" value="Lcp-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018713">
        <property type="entry name" value="MPAB/Lcp_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37539:SF1">
        <property type="entry name" value="ER-BOUND OXYGENASE MPAB_MPAB'_RUBBER OXYGENASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37539">
        <property type="entry name" value="SECRETED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09995">
        <property type="entry name" value="MPAB_Lcp_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="436"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic" evidence="2">
        <location>
            <begin position="122"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ33817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="470" mass="53122" checksum="5ACFBB4176490B0D" modified="2011-01-11" version="1">MGVFSFARPSDDVRVVWNYSFRWTEDHIPKDKTEHLRQTYDKVGAAAVARIQEIHQQALIEKSGNAEHLFKLDLFAVLQEHHEKDEALGQLWDEVYTVPDWVDWEQIARGQKFFYRYALANLMGFALQGFVGENSASGGVVEVLVRTGGFRTSVLFRRLLETFQMLLEVTDSLEYVQPGGRGHTTAVRVRLLHCMVRQRILKIVQHKGPSYYDVEAYGVPINTLDSLHALTTFCCNHAFIQLPLMGISVPQQEIEDYVALWRYLGHVLGTPTDHFTSAAKAKILMDSMSFNERLVTDMSLVAGHNFVETVRDVPPVNLSAGFIEAGSRVLNGDALCDQLGMGRPGVYHYACFRGFCWLVRTLAMAQRWFPRFDEKVVDYNREMLHKAIIQSQGGLGGGTKMEFKHVPDGTLTKKEDRLGKIAQLRFYERPLDLACFVYFVLGSLFVAGGLTVAVKVAIKLVASVHYHTLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QS83</accession>
    <name>E3QS83_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Lipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_08854</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697373">
        <property type="protein sequence ID" value="EFQ33710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097730.1">
        <property type="nucleotide sequence ID" value="XM_008099539.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QS83"/>
    <dbReference type="STRING" id="645133.E3QS83"/>
    <dbReference type="GeneID" id="24414219"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08854"/>
    <dbReference type="eggNOG" id="KOG4569">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032957_1_0_1"/>
    <dbReference type="OrthoDB" id="426718at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051299">
        <property type="entry name" value="AB_hydrolase_lip/est"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46640:SF1">
        <property type="entry name" value="FUNGAL LIPASE-LIKE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46640">
        <property type="entry name" value="TRIACYLGLYCEROL LIPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G06510)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180731" evidence="3">
        <location>
            <begin position="18"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="Fungal lipase-type" evidence="4">
        <location>
            <begin position="108"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ33710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="303" mass="32381" checksum="C2B7C9DC7B732619" modified="2011-01-11" version="1">MLAKLSLFALLSAAVLATPLRDARAPAAALDERAVAVTAGDLANFEYYVQVVAATSCNSEPGAPITCSADACPDLQANDAKIVTTFSGYTTGIEGLVALDPVRQLIIVVILGSINVRNWITDFVFVFEDCDLVEDCKAHAGFLTAWKEVKGEILDAVNATKTANPSYTVVAVGHSLGGAVITIAGAYLRLHGYPLDIYTFGSPRVGNEAFATFVTAQSGAEYRLTHVDDPIPRQPPLLFGYRHTSPEYWLSTGNATTINYSLDEIKVCEGFSNTDCNAGTTGLDTEAHVYYLRATRACKPDKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSD5</accession>
    <name>E3QSD5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">5'-nucleotidase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_08906</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the 5'-nucleotidase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697373">
        <property type="protein sequence ID" value="EFQ33762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097782.1">
        <property type="nucleotide sequence ID" value="XM_008099591.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSD5"/>
    <dbReference type="STRING" id="645133.E3QSD5"/>
    <dbReference type="GeneID" id="24414271"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08906"/>
    <dbReference type="eggNOG" id="KOG4419">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005854_7_2_1"/>
    <dbReference type="OrthoDB" id="10252235at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07406">
        <property type="entry name" value="MPP_CG11883_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="entry name" value="5'-Nucleotidase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008334">
        <property type="entry name" value="5'-Nucleotdase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041821">
        <property type="entry name" value="CG11883_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575:SF48">
        <property type="entry name" value="5'-NUCLEOTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="5'-NUCLEOTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02872">
        <property type="entry name" value="5_nucleotid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01607">
        <property type="entry name" value="APYRASEFAMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="5">
        <location>
            <begin position="25"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="5'-Nucleotidase C-terminal" evidence="6">
        <location>
            <begin position="322"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="526"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="533"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ33762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="634" mass="70675" checksum="E5C520815290E74D" modified="2011-01-11" version="1">MPKNTPAPDEPVVTFSSGSQEPVALRLLHLNDVYHLEPSSAEPVGGVARFVTAVNEYRSHDRFQGQPELVTLFSGDVFNPSLESSVTKGEHMVPVLNKIGVDCTCVGNHDFDFGVKQFESLTAKCNFPWLLANVLDPALGENVPLGNAKHTHMLTTSNGIKIGLVGLGEREWLETINSLPPNIIYKSASETAKELVPQLRAQGADIVICLSHQREPNDNKLAEKTDGLFDIILGGHDHYYGHSFINGTHVLRSGSDFKQLSYIEVRKKPDSSGKWDFDILRRDIVSSIAEDQETLKLTEDLTSKLKQSLAKSVGWTASPLDARFTTVRMKESNMGNFVCDVMRHYHNADCALMAAGTIRGDQIYPPGAIRVRDITNCFPFEDPVIFIRVTGKQLWDALENGVSQYPAQEGRFPQVSNIEYTFDPSKPPSSRIVSASVGGEPMDFERKYTLATRGYMGRGKDGYTSLLVEPEGGTAEEIVCEENGILISAMLRQYFMSLKTVGRWKNLSENWLDVAEKCHSPVEPRKMWETPAATGTSDPQPETTSRSWAEWMIKRHMLNTKPPKDDESDDSDEEVDTVAQIDTEILIMRKFFARWANKAGVKAEVCDSLREGEFSVDWTRVIAPVLEGRIKMIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSN6</accession>
    <name>E3QSN6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Dimethylaniline monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_09018</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FMO family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697374">
        <property type="protein sequence ID" value="EFQ33874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097894.1">
        <property type="nucleotide sequence ID" value="XM_008099703.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSN6"/>
    <dbReference type="GeneID" id="24414383"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09018"/>
    <dbReference type="eggNOG" id="KOG1399">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006909_5_3_1"/>
    <dbReference type="OrthoDB" id="66881at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000960">
        <property type="entry name" value="Flavin_mOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000332">
        <property type="entry name" value="FMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00370">
        <property type="entry name" value="FMOXYGENASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="49"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ33874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="475" mass="53225" checksum="40065D89F4B5BD3A" modified="2011-01-11" version="1">MAPRYSSVAIVGAGPSGISAVKALSEEKAFDRIQLFDRRHRVGGTWIYDEEPEPFSTSSSQPDREIPEKLPRSLPPASENITARTGLYPSLDSNVGSQVMAFTYKPFPPVNSATSISRFGRGNPTHPHAAVAGYLEEIAEPFSHLFTFDTHVERVEKAGKKWRLTLRKTQHYLKHEKRDYWWQDTFDAVVVATGHYGVPYVPSIPGLEETFAALPQRFEHSKAYRSPEDYVNKKVVVVGGNVSASDTVSEIHNIVSDPLYVSQRGYNEILKDAWELPNVVRKPQITRISVGPDNLVKVSFSDGTEAGGIEKVHFGTGYRLSYPFLRPDPVTPSGRLAGFYQHIFNVADPSLAVVGQVKAAISFRVYEYQAVAVARYFANRGGGLPSPREQDEWEVKRLRYKGPTSEFHEIKPDFKEYFDFLCRVAGKPAPGTDAYELPAWQDEWAVLGFGVLALKQKWWGELKEKGQKTSIKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QT43</accession>
    <name>E3QT43_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Mannan endo-1,6-alpha-mannosidase</fullName>
            <ecNumber evidence="4 10">3.2.1.101</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_09175</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Random hydrolysis of (1-&gt;6)-alpha-D-mannosidic linkages in unbranched (1-&gt;6)-mannans.</text>
            <dbReference type="EC" id="3.2.1.101"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycosyl hydrolase 76 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.101" evidence="4 10"/>
    <dbReference type="EMBL" id="GG697375">
        <property type="protein sequence ID" value="EFQ34031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098051.1">
        <property type="nucleotide sequence ID" value="XM_008099860.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QT43"/>
    <dbReference type="STRING" id="645133.E3QT43"/>
    <dbReference type="GeneID" id="24414540"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09175"/>
    <dbReference type="eggNOG" id="ENOG502QSWP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025694_1_2_1"/>
    <dbReference type="OrthoDB" id="4187847at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008496">
        <property type="term" value="F:mannan endo-1,6-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009272">
        <property type="term" value="P:fungal-type cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.20:FF:000006">
        <property type="entry name" value="Mannan endo-1,6-alpha-mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005198">
        <property type="entry name" value="Glyco_hydro_76"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014480">
        <property type="entry name" value="Mannan-1_6-alpha_mannosidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12145">
        <property type="entry name" value="MANNAN ENDO-1,6-ALPHA-MANNOSIDASE DCW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12145:SF36">
        <property type="entry name" value="MANNAN ENDO-1,6-ALPHA-MANNOSIDASE DCW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03663">
        <property type="entry name" value="Glyco_hydro_76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016302">
        <property type="entry name" value="Man_a_manosd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 10 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="343"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="408"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="408"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="418"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR016302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ34031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="439" mass="48392" checksum="EF571DE8564C61A8" modified="2011-01-11" version="1">MKFYDGNQTGMIPGILPGPPDSGLGDYYWWQGGAMMGTYVDYWYYTGDDSYNHVIMEGMLHQTGSDRDYMPRNHTLSLGNDDQGFWGMTAMLAAENKFPDPPEDKPQWLALAQAVWTTQADPERHDSACGGGMRWQVPRTNVGYDYKNTISNGCFFNIGARLARYTGNDTYARYAEETWDWLWAVNYIDHENWMATFSYNIAILMQGCAFLANYTGEQKWFDRTQALANRAIDDFFADGAAYEIPCEFETGRCSQDMLSFKGYLHRWMTVVTQLVPSTRDLILPVLRNSTAAAIRQCTGGASGRVCGFYWTTGQFVDPAVDKTSGAGEAMNVLAAVQSLLDVDPPATNDTGGTSKGDPNAGLNSHPFREHSPVTAGDRAGAGILTAIVLVSAVAIWGWMSIPHAEWNESKGKEKEKMSPTSIDAGNSQESVTVSNGTLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTG5</accession>
    <name>E3QTG5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycoside hydrolase family 79 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_09297</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697377">
        <property type="protein sequence ID" value="EFQ34153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098173.1">
        <property type="nucleotide sequence ID" value="XM_008099982.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTG5"/>
    <dbReference type="GeneID" id="24414662"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09297"/>
    <dbReference type="eggNOG" id="ENOG502QW09">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022148_2_0_1"/>
    <dbReference type="OrthoDB" id="2796951at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052974">
        <property type="entry name" value="GH79_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031728">
        <property type="entry name" value="GlcAase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36183">
        <property type="entry name" value="BETA-GLUCURONIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36183:SF2">
        <property type="entry name" value="BETA-GLUCURONIDASE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16862">
        <property type="entry name" value="Glyco_hydro_79C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180790" evidence="2">
        <location>
            <begin position="21"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-glucuronidase C-terminal" evidence="3">
        <location>
            <begin position="422"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="553"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="553"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ34153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="608" mass="66006" checksum="42B58E63139F4E98" modified="2011-01-11" version="1">MAPLQSRVLVGCGLISAAFAADNILSLTLSEDVPHNVSANIDPSFAGFGIELDHLYYFMGDETPNDLSINLLENLAEFTGRPPYVRLGGNTQDYVIYDDSQDKWLIEPNPRPLADGHVPADNFIIGPRFMDIANRMPEGTPIVWGLNLGYSEPDYLHQLTTMVTQILDRCTNLNLMSFELGNEPDLYGNNGFRTSSWTGSQYVKEWRERADALWEKVLQPRGLRSNLFEASASTAWVAGTGFEIKDLESHGIDDKPSNSDVGYITSWNQHNYYYFVGSFPYPLTLDYMMRFDTTNAQFESAIQAQITQAEQTNHPFALREMSVVGPLGVEGLSNTFAAALWTFNFLFYAATINISSVQFHMTYDSNASAWQPTAMFGRDRFVRPLYYGIAAFGQTIGRSCTARVAQAEITDYPSAHNEYVKAWSVYQGDSLSSLVVLNGKVANVSETNKESITVDVTLPASLAGQTLHLSYLTSDGADATSGTTWNGISFEQGNDGKMTQVTKEDITVKVGDDGKASIPVRDSEAVVANIGGKVGSGEPDSAACDALATSSRGVGAATKSTPGSSGEPSHSSSDDGDDDSSAAGLASRKSIYTCIAWSLAVSIGAFYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTI1</accession>
    <name>E3QTI1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_09313</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697377">
        <property type="protein sequence ID" value="EFQ34169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098189.1">
        <property type="nucleotide sequence ID" value="XM_008099998.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTI1"/>
    <dbReference type="GeneID" id="24414678"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09313"/>
    <dbReference type="eggNOG" id="ENOG502S2Z9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048135_0_0_1"/>
    <dbReference type="OrthoDB" id="4850847at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549:SF30">
        <property type="entry name" value="MID2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180794" description="Mid2 domain-containing protein" evidence="7">
        <location>
            <begin position="23"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="284"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="24"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="243"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="311"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="416"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="57"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="250"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="315"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="363"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ34169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="453" mass="46489" checksum="4659A75355D67DFC" modified="2011-01-11" version="1">MRLGSAGLTALLWSAIATLTTANPIANNDSRPMPVLRPRQGGTGVTPTPTPTPTPTPTGDSTTPTTATTASEEEATTTITITTTVGGGGGDRTTTATTVVLRTITTTILVTSTSFQTTTVTSSDVATATVTNYVTSTVLAKRSLEVLPLDAPVPPAQITPAADDYRRRAFVEKRALVTVVVTVTGPAAGVSTVLNTRTSTVVFTTTSNTVFTSVLTSTQFNNAQTTITVESTLTVTSTSIDTAAPTTVDTGPTTGIISTPTESSGAQSTSGSDDSGGLSTGAQAGIGVAVGIVGLAALLAIGWWAYKRHKANRPSRSDLDDMRAYDPNGPSPLHEPTGMSEAGAGFRGAGAGAMRRQPVPKHQLSPPSQSVSPLSNQTVSPAGAGYSRPPTGGAQEFGGTRVMPAEMGGDEVVEIGDSEPRAQQPLQHTPAAGRPYNSGPVPDMYEMPTERYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTI2</accession>
    <name>E3QTI2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_09314</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697377">
        <property type="protein sequence ID" value="EFQ34170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098190.1">
        <property type="nucleotide sequence ID" value="XM_008099999.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTI2"/>
    <dbReference type="GeneID" id="24414679"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09314"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_1_1"/>
    <dbReference type="OrthoDB" id="2962993at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000034">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000068">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF91">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="139"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="208"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="317"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="344"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="369"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="404"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="433"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="49"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ34170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="495" mass="54868" checksum="3254C43236195641" modified="2011-01-11" version="1">MDASKKEMLDEAGAGLSPGASSPDMAARDPDPVDAAAEKKIVRKLDMHIIPLVMLLYLFSFLDRVNIGNARLYNLERDLNLQGNQFQVAVSILFVTYIVFEVPSNLVLKLFTPCRWIAFITISWGIIATLTGLVNSYGALIACRLLLGAVEAGLFPGLNVYLTFFYSKHELALRVGYLFVSAAIAGGLGGLLAYGIGHMEGVAGMSGWRWIMIIEGLPTVIIGVVTYFALPNDAGSAYFLTDEEKAIMARRRGREYGNTSSAQEFSREDMFKAFKDWKVWVFSVAQFGADTMLYGFSTFLPTIINSLGKWRPEQVQLLTVPCYFLGAVVYMSMAFLSDRMQKRGLFCVIFGSISVIGYGVLISPASNGVHYFGCFLVAAGLYVVVGLPLAWLPNNSPRYGKRTTASGMQLTIGNCSGVMSSFIYQAIDKPRYIRGHAVTLSMVGMATCIYGFMWFWYWRENKQREAGHIQSKHADLSDDEMAELGDDSPRYRYTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTY4</accession>
    <name>E3QTY4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dockerin type 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09466</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697379">
        <property type="protein sequence ID" value="EFQ34322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098342.1">
        <property type="nucleotide sequence ID" value="XM_008100151.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTY4"/>
    <dbReference type="GeneID" id="24414831"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09466"/>
    <dbReference type="eggNOG" id="ENOG502SHSP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042057_0_0_1"/>
    <dbReference type="OrthoDB" id="5319191at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045690">
        <property type="entry name" value="DUF6055"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19527">
        <property type="entry name" value="DUF6055"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180810" description="Dockerin type 1" evidence="1">
        <location>
            <begin position="21"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="433" mass="46757" checksum="28B7C53CEF21A601" modified="2011-01-11" version="1">MTRSNQLFAVFLAFATGAFAAPRAGFRAPFKVVARDEPTEFEPQTNAGPGGNDFQDSARFRVYNGGDAAADSLAMLEGAYDCFVGTLGWRSSGLSFNPGSDDGPYYMTNVYSMSDLGGAAGVMHSEAESGAGWLEVVDTYLANPTITVHEYGHALHYHQRTWVNQQRTGAWWETVANWVADTYITSPICADARTKHNSPEGRTLFDVNKVIGDSFQVIVDGTVDSGNYYQAWPFLTYLTNNPDNIEGLGEDTLHQMMVQYEQDSNETPLHTLDRVLGGNATAGEAVGRYWARMAYVDIAHQQAQEIFNQARDTINFANVDESGSGYTVKSDRAPRYMGANIIPLTTSGGQVDVKVTSSGEFTATLAIKGSSEVRYVVLANGAGSAEVASGEEASLVIANTPKTLILYDGFQLADSEANKGLDYSFTLTGATVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3QU95</accession>
    <name>E3QU95_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Serine/threonine-protein phosphatase 2A activator</fullName>
            <ecNumber evidence="10">5.2.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Phosphotyrosyl phosphatase activator</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_09577</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the PTPA-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="10"/>
    <dbReference type="EMBL" id="GG697380">
        <property type="protein sequence ID" value="EFQ34433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098453.1">
        <property type="nucleotide sequence ID" value="XM_008100262.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QU95"/>
    <dbReference type="STRING" id="645133.E3QU95"/>
    <dbReference type="GeneID" id="24414942"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09577"/>
    <dbReference type="eggNOG" id="KOG2867">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030733_2_0_1"/>
    <dbReference type="OrthoDB" id="16120at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008160">
        <property type="term" value="F:protein tyrosine phosphatase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000082">
        <property type="term" value="P:G1/S transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd04087">
        <property type="entry name" value="PTPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1150:FF:000003">
        <property type="entry name" value="Serine/threonine-protein phosphatase 2A activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004327">
        <property type="entry name" value="Phstyr_phstse_ac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043170">
        <property type="entry name" value="PTPA_C_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037218">
        <property type="entry name" value="PTPA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10012">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10012:SF3">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 2A ACTIVATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03095">
        <property type="entry name" value="PTPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016325">
        <property type="entry name" value="Phstyr_phstse_ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140984">
        <property type="entry name" value="PTPA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0697">Rotamase</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ34433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="428" mass="46053" checksum="C46F8AA5DD2BAFCE" modified="2011-01-11" version="1">MDPASSTTATPPPPPPSQTPQQPAFPSIKPLPRAPRSFQTPTKRINTGADLSTFLTTTAYRDILLFLLQLNRSLCPRRPPGAGAGPATTYPLTSLPPAARLPPSIAALQNLLAAAESLIDLAPPDPGPRRFGNVSFRKWHELLAERAPALLAEHLPDSVLAFPTAPVSDPPSSELLSYLLGAFGSPQRLDYGTGHELSFLAFLGSLYKLSFFADDVPTSPAPGEPDTAALDRTIVLGVIEPYLRVVRRLILTYTLEPAGSHGVWGLDDHSFLPYIFGSAQLTSPVSSDADPMPTEGSVRGAPKTGDIVKPAVVEAQRSENMYFSAVGFINDVKKGPFWEHSPILFDVSGVKDGWGKINKGMLKMFNAEVLQKFPVVQHFTFGSLFAWDQDPDAAPVSQSVHSANQPSYNYPATTAPPLKDVAECIGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUB1</accession>
    <name>E3QUB1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_09593</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697380">
        <property type="protein sequence ID" value="EFQ34449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098469.1">
        <property type="nucleotide sequence ID" value="XM_008100278.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUB1"/>
    <dbReference type="STRING" id="645133.E3QUB1"/>
    <dbReference type="GeneID" id="24414958"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09593"/>
    <dbReference type="eggNOG" id="ENOG502QUV4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018354_4_2_1"/>
    <dbReference type="OrthoDB" id="9983560at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050432">
        <property type="entry name" value="FAD-linked_Oxidoreductases_BP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878:SF91">
        <property type="entry name" value="FAD BINDING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G12070)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878">
        <property type="entry name" value="GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180829" evidence="3">
        <location>
            <begin position="21"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="4">
        <location>
            <begin position="115"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ34449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="586" mass="64645" checksum="FF75636BCACE22D5" modified="2011-01-11" version="1">MARWLSSLILCAVMESTGFAAAIRCKVYPGDTAWPLDEAWTSLNERVDNRLLKPRPQAAACYNGPEYDAVACARMSANWTNSYIHLEDPIEMFSPVYQGLTCLPPSIYDSGNCTMGGFPWYVINATSPKHVQEGVKFAAETGVRLVVKNTGHDFSGKSGGGESLSIWTRYLKDVEYVEEVIDAVEGYSGPAFKCGTGVQAFEIYKVASEYNKVVVGGEGETVGVMGGYIQGGGHSPLSSIYGTGADQALAFEVVTADGELVTANHTQNSDLFWALRGGGGSTFGVAISVTVKAFPDVTTTAAAFKFSTADGISNETFWAGVRSYFDSFIHNADNGTYAYFVMLPNNPGPGNFLFQMTPFFAPNKTAEDVNALFDPWFAELRKLGIDFTPNMTQYGSFYPAWQDFFPLEAVEKVNVQSGSRLFPRRNFEDVELKQATFDAIRISLETNHVFVGFNIKATSPDDPDNAVNPAWRENILFAIQSVRWPVNATTDQILEARKGFTLGDMQRWRDVSPGAGSYLSESDRMEPNFQQSFYGDTKYPRLLELKRKWDPNDVFYAATAVGSEFWTIHTADGLPHENGKLCRVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUE5</accession>
    <name>E3QUE5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glutathione-dependent formaldehyde-activating enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_09627</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697380">
        <property type="protein sequence ID" value="EFQ34483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098503.1">
        <property type="nucleotide sequence ID" value="XM_008100312.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUE5"/>
    <dbReference type="STRING" id="645133.E3QUE5"/>
    <dbReference type="GeneID" id="24414992"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09627"/>
    <dbReference type="eggNOG" id="ENOG502S13F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038839_0_0_1"/>
    <dbReference type="OrthoDB" id="5422068at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1590.10">
        <property type="entry name" value="glutathione-dependent formaldehyde- activating enzyme (gfa)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337:SF40">
        <property type="entry name" value="CENP-V_GFA DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337">
        <property type="entry name" value="GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ34483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="361" mass="39688" checksum="557F00A93544ADCC" modified="2011-01-11" version="1">MTPTSMGVSCLCGTIAQRVSPRRTDSKVTEISITHSDTDRRATEHIGADGYTRCFCRMCGCHIFRRKAVGEQTEWEAATGVLIDSTRDNAEHDARFTVHTSVSDTKDGGISVWLPQIDGHTLDAARNPDFSVELQESSSLLPLTSPLVPADSLPASCACGAVSFHITRPDERSYLPHSGFSDLLYPACKHSEHIIKSPDSVKWWIRADGTKYLAGTCACRPCHLASGFEIQTWAFVPRENIFLHTPGPDERRAVLPLDFAALPPGVLRTYESSPGVLREFCGGCGATVFWHDIWRPDVIDVSVGLLRAPEGARADTWLDWWTGRCSFEEEASRGRTGEPARMARRLIDGLERGLGSQAQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUN0</accession>
    <name>E3QUN0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_09712</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Mycotoxin biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="GG697381">
        <property type="protein sequence ID" value="EFQ34568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098588.1">
        <property type="nucleotide sequence ID" value="XM_008100397.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUN0"/>
    <dbReference type="STRING" id="645133.E3QUN0"/>
    <dbReference type="ESTHER" id="colgm-e3qun0">
        <property type="family name" value="Duf_1100-S"/>
    </dbReference>
    <dbReference type="GeneID" id="24415077"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09712"/>
    <dbReference type="eggNOG" id="ENOG502QPTG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034451_0_0_1"/>
    <dbReference type="OrthoDB" id="249703at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.110">
        <property type="entry name" value="acylaminoacyl peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010520">
        <property type="entry name" value="FrsA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050261">
        <property type="entry name" value="FrsA_esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22946:SF13">
        <property type="entry name" value="ALPHA_BETA HYDROLASE PSOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22946">
        <property type="entry name" value="DIENELACTONE HYDROLASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06500">
        <property type="entry name" value="FrsA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ34568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="425" mass="47646" checksum="D1EE68141B5063A8" modified="2011-01-11" version="1">MDILPWEFFNFEFIRVLSMAPTHGADVGECLEAASKIKKNDPEIWYQAWAEAADLAEEAADTALKLGDREAARWAFLRACNYRRASEYMLHVNPYDTRLLGIMEKSVSNFRSACDLFDNTVETFEIPYENTKLPGYMYLPTPKSGGKPRGEKVPLLLAMNGFDSTQEELYFFIASGSASRGYAVMTFDGPGQGIVLRRPGQPPIRRDWEVVVSAVLDSLWKLVDEHPEWNIDLDRIGIMGMAMGAYFALRGATDPRIKACISCDGFYDFGPQVRLRSPFFLKYLTDGQADAILEWASGFNMQHKLEFGHLRMVFGTKSCIDALRKLGSISLEAPGEKPICAKVKCPVMVMGARDTIYTLETHLTYQKLAEYRGSEEGLTLWDPVGPGQGSLQAKVGAVSRLQMKVFSWLDEVFGIQRPPIAKQPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUV7</accession>
    <name>E3QUV7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">GMC oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_09789</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697382">
        <property type="protein sequence ID" value="EFQ34645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098665.1">
        <property type="nucleotide sequence ID" value="XM_008100474.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUV7"/>
    <dbReference type="STRING" id="645133.E3QUV7"/>
    <dbReference type="GeneID" id="24415154"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09789"/>
    <dbReference type="eggNOG" id="KOG1238">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002865_6_1_1"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF115">
        <property type="entry name" value="DEHYDROGENASE XPTC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180868" evidence="4">
        <location>
            <begin position="21"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="5">
        <location>
            <begin position="298"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="552"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="595"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="44"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ34645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="616" mass="66943" checksum="74C1F7AAFCD6A206" modified="2011-01-11" version="1">MPYFLLVLLLLTQSFVLSRCQTQVQKSVNSVGAEYDYIVVGGGTSGLVVANRLSQNTSKTVLVIDYGDFVNTVNVTVPYFTTLDQSANLYNITSIPQAHLRNRTSRLRIGATVGGSSTVNGMAWDHGSVADYDAWEALGNPGWGWDSFMKYFRKSSAFLPPSQKYVDKYNYQWTPEAYGDGPVKIGFPSWQWPEAAFQAQAWVENLKAPVLRDGADGDNVGIAWLPQNSGGESATRSTSETAYFSPISGRQNLHLIVRHYGAAIRFEGNKTVGINISSRDNSSETKFVRSENIVLAAGAVNTPRILQLSGIGAEKLLSSLDIDMVVDLPGVGANFHDHPTIFMVYDFANDTALNPNLMSNEIFYNRSWAEYETNRTGPHTHAWGNKAVFTSLQDLDPANYQSIAEAVSKQEPLQHLPQVYAENPALVKGYLQQRKVLREHFLNPKAGIVEFAFGGSGTVPVALQKPLSRGTISINSTNPDPSIAPLIDFNTISNPVDSLLLIRAVAKARAFMSSPSIQPLGAVELVPGLGVSSDAQIEAVMKESWLASSLDHPAGTAAMMPREWGGVVDSNLKVYGVEGLWVVDASIMPILPAAHTQATVYAAAEHAADIIRGCEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUY1</accession>
    <name>E3QUY1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TfdA family Taurine catabolism dioxygenase TauD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_09813</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TfdA dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697382">
        <property type="protein sequence ID" value="EFQ34669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098689.1">
        <property type="nucleotide sequence ID" value="XM_008100498.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUY1"/>
    <dbReference type="STRING" id="645133.E3QUY1"/>
    <dbReference type="GeneID" id="24415178"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09813"/>
    <dbReference type="eggNOG" id="ENOG502QT05">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036005_0_0_1"/>
    <dbReference type="OrthoDB" id="10257314at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000907">
        <property type="term" value="F:sulfonate dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044273">
        <property type="term" value="P:sulfur compound catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.130.10:FF:000003">
        <property type="entry name" value="Alpha-ketoglutarate-dependent taurine dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051323">
        <property type="entry name" value="AtsK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT SULFONATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468:SF1">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT SULFONATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="7">
        <location>
            <begin position="98"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ34669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="382" mass="42781" checksum="8C0A9ABDEAAE88B1" modified="2011-01-11" version="1">MAPSATETTTVTDPVNLPVNNLRLYADGSGDYKELSPVVYDKDAEAKGGDGHKGAKYPHYLPTWNPEQKYPPLEPFQHYEHGKDADPSYPDLLPKEAEVTDLTPTIGTEVRGIQLSKLSNAGRDQLARFVAERKVVAFRGQDFADLPIDKALEFGGYFGRHHIHPTSGSPEGFPEIHLVHRAAGDRSAEKFFATRTSSIAWHSDVSYEQQPPGTTFLYILDKPETGGDTLFCNAVEAYNRLSPLFQERLHGLQAVHSGIEQINASVSKGSIKRREPVANTHPIVRTHPVTGEKALYINPQFTREIVGLKKEESDALLKFLYEHIAWGADFHARIKWEEGTVVVWDNRVTQHSALIDWNNGSRRHLARITPQAERPYETPFKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QV87</accession>
    <name>E3QV87_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SRPBCC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_09835</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697383">
        <property type="protein sequence ID" value="EFQ34691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098711.1">
        <property type="nucleotide sequence ID" value="XM_008100520.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QV87"/>
    <dbReference type="STRING" id="645133.E3QV87"/>
    <dbReference type="GeneID" id="24415200"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09835"/>
    <dbReference type="eggNOG" id="ENOG502S64G">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069867_3_1_1"/>
    <dbReference type="OrthoDB" id="509124at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07822">
        <property type="entry name" value="SRPBCC_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019587">
        <property type="entry name" value="Polyketide_cyclase/dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36166">
        <property type="entry name" value="CHROMOSOME 9, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36166:SF1">
        <property type="entry name" value="SRPBCC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10604">
        <property type="entry name" value="Polyketide_cyc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ34691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="152" mass="17244" checksum="0D120484E4AC1F81" modified="2011-01-11" version="1">MVFSNSVSAEIEIKASPADVRSVFLDFQRYKDWSQGWTLTPMEAGKNPSDLKDGDQIQAKMKDMTFKPVIKENTSDALHWVGSLPGIFTGRHQFYFKPSDVNPGGTRFVQAEDFSGLFAFLMAPGWSFRDKTLAGWNEFNADLKKEVERRPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVM1</accession>
    <name>E3QVM1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Serine carboxypeptidase S28</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_10053</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S28 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697385">
        <property type="protein sequence ID" value="EFQ34909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098929.1">
        <property type="nucleotide sequence ID" value="XM_008100738.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVM1"/>
    <dbReference type="ESTHER" id="colgm-e3qvm1">
        <property type="family name" value="Prolylcarboxypeptidase"/>
    </dbReference>
    <dbReference type="MEROPS" id="S28.004"/>
    <dbReference type="GeneID" id="24415418"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10053"/>
    <dbReference type="eggNOG" id="KOG2182">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023630_0_0_1"/>
    <dbReference type="OrthoDB" id="1735038at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070008">
        <property type="term" value="F:serine-type exopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000251">
        <property type="entry name" value="Extracelular serine carboxypeptidase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008758">
        <property type="entry name" value="Peptidase_S28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010">
        <property type="entry name" value="PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010:SF117">
        <property type="entry name" value="SERINE PROTEASE 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05577">
        <property type="entry name" value="Peptidase_S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003181012" evidence="6">
        <location>
            <begin position="22"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ34909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="558" mass="62307" checksum="0B868F59B53292A4" modified="2011-01-11" version="1">MAAHWKLRACMLLGAAQAAAGLGPQHRLMNREAWDAIHSTPQLQVESVSTFSKYPEYNLSVPIDHFHNDSRYEPHSDEYFNLRYWFDAKHYRPGGPVIILAAGETDGKDRLPFLDHGILSILAKATGGVGVVLEHRYYGKSFPVPDLSTENLRFLSTDQALADTVYFAKHISFPGHEDLNLTAPGTPYLVYGGSYAGAFAAFLRKLYPDVFWGGISSSGVTAAIIDYWEYYEGARLFAPGDCAETTQNLTQVVDNVLLAKSEQVKPSHVSQLKELFGLGPLQDDDFASTISYGISGLQSTNWDPASDSTSFGTYCATVSSDSVLFGSTRHLRPAVEELLFVSGADVKLTNRLLNYAGYVRNYVKKGCRGGDLVKCFSSRKREGYQNISVHQGYERSWFYQVCTEWGYFQTGSGVPEDQLPLVSRVIDVEYSSIYCREAFNITKPPNVDAINKHGGFNFSYPRVAIVDGEADPWRPATPHKIGLDRKSTTSEPFLLIELGVHHWDENGVKPENVTPDFPPASIKKVQAQEVEFVTAWMKEWRDAQSQSNRQEEPVFEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVR5</accession>
    <name>E3QVR5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Amino acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_10097</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697386">
        <property type="protein sequence ID" value="EFQ34953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098973.1">
        <property type="nucleotide sequence ID" value="XM_008100782.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVR5"/>
    <dbReference type="STRING" id="645133.E3QVR5"/>
    <dbReference type="GeneID" id="24415462"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10097"/>
    <dbReference type="eggNOG" id="KOG1286">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007946_12_1_1"/>
    <dbReference type="OrthoDB" id="10062876at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF6">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="79"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="282"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="342"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="387"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="413"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="465"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="490"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="7">
        <location>
            <begin position="52"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ34953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="559" mass="61578" checksum="6AA313D1DBEE47E5" modified="2011-01-11" version="1">MTTSKHAEKGPPFSSVDNDSGHGSNIDIGVGSILNTKAGSQALHRKLRGKEVQLFAIGGAIGTSLYVQMGAALPKGGPAGLFIAFIIWGCVMWAVNECFAEMVTYVPVPSPFVRFAGEWVDEALGFAMAWNFFLNMAILVPFEIVAMGIMITFWTDAVPIVAIIVPMIALYALLNIITVRYFGISEFYLSIFKVLLMIGLFFFTFITMVGGNPLQDAYGFRFWQSPGAFVEHNASGNTGRFLGILSCMYQASFSVCGPEYISMVAAEAENPRRILPPAYRSFVWRILFFFVGSALCMGIVIPYDDSTLAVILGGESGGKGTGAASPYIIAMNRLQIHVLPHIVNALIMTSIFSAGNGLLFSATRVLHGMSLTGYAPKVFSRCTKNGVPLYSLLLSLSFCLLAFMQLSSTSADVLVYLVDLITCCQLLNYGFTALTYRHFYAALKKQGISRETLPYKGRFQPYTSYFAMGGTLFMLLAAGYDLFLTGGWDVMWFFLDYGMIGFFILAFIGWKLFFKTRYVRPGTAEISLGGIKEEIDQYEALYIPREPGRVGRLINKVFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QW12</accession>
    <name>E3QW12_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Btz domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">GLRG_10194</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CASC3 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697387">
        <property type="protein sequence ID" value="EFQ35050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099070.1">
        <property type="nucleotide sequence ID" value="XM_008100879.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QW12"/>
    <dbReference type="STRING" id="645133.E3QW12"/>
    <dbReference type="GeneID" id="24415559"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10194"/>
    <dbReference type="eggNOG" id="ENOG502QUZZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018142_0_0_1"/>
    <dbReference type="OrthoDB" id="5413466at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035145">
        <property type="term" value="C:exon-exon junction complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018545">
        <property type="entry name" value="Btz_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044796">
        <property type="entry name" value="MLN51_plant"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46837">
        <property type="entry name" value="PROTEIN MLN51 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46837:SF5">
        <property type="entry name" value="PROTEIN MLN51 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09405">
        <property type="entry name" value="Btz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01044">
        <property type="entry name" value="Btz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="11" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="10" id="KW-0866">Nonsense-mediated mRNA decay</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="8" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Btz" evidence="14">
        <location>
            <begin position="132"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="468"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="541"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="596"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="148"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="227"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="470"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="552"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="603"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="614"/>
            <end position="649"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EFQ35050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="730" mass="79731" checksum="383DA14F03FEA9CA" modified="2011-01-11" version="1">MAAPRRRKIGHRRRIEDEEDGEGGPDQLDLDDDSLTEGSIVSDDHDHGNDSDTSNIDEASPVAPNPRKAAGHGNGNGNVKPAVRSASALGSQMIDKVTSDADEMLQGLSISDRPEPAQQGQADAAASPPKSSAPLVVSSHSSRLAEPVNERRRREHEEYKRRRDEDPAFVPNRGAFFMHDHRHAGPSANGFRPFGRGRGRGRGGGIGGPYAPMKYAQQEPSRRHPANPSSQLHNPTDPLTSGQWAHDMHEVVAEPPPSRQPRHLPVDTEGPANGNGFIPTCPSNPTPINRTLSTERHIGNVQVRVSLPVLDKAPSAFAMPVKQYTKLPDHRPPLRRDKPVRISLPDNPPKYIFPAVDRSFIFIPRAMRPNQQRTRGKPRSGLGSMGGFSRRTSVFGGSYYGSAYSPSVALSRRSSLAPDGRDYLFSPTGSVMSRAPIPVDNPRPIVRLPPANQPFMGQDVYPVPMPMPMQQNETSINDLPQPQTHPLPQKPAFQENRQTQIPMHQPRPQKAVSVTNIESPTLNQGPQAFQQAFHQQVPVQVSNGHPQDAHSRQPSYPTQHSTGTPLSQIPERAIHAAPFQPNTFQQQSFYNQPYPMMQQQQQQPPPPPPPPYYYPGQYNSNMGPPAAAASFAPSGQPGQGQGYPHQTQPDPAAAQANGQVPAGPNLVAQEVNGMVYYYDATQMPPMNAYQGYQPPPQFGPGVSGMGGMVTPSPDGFYYQQPAPGMVYYSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QW38</accession>
    <name>E3QW38_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphoribulokinase/uridine kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10220</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697387">
        <property type="protein sequence ID" value="EFQ35076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099096.1">
        <property type="nucleotide sequence ID" value="XM_008100905.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QW38"/>
    <dbReference type="STRING" id="645133.E3QW38"/>
    <dbReference type="GeneID" id="24415585"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10220"/>
    <dbReference type="eggNOG" id="KOG2702">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067202_1_1_1"/>
    <dbReference type="OrthoDB" id="6362633at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10285">
        <property type="entry name" value="URIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphoribulokinase/uridine kinase" evidence="1">
        <location>
            <begin position="26"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="243" mass="27604" checksum="072522E0CF23F122" modified="2011-01-11" version="1">MEQQVTRLVEKAWDKFQKTPADQRLMIGIAGIPGSGKTTLSQLLTTRLNARAATLDPSNPSRATHPPPTAFVPMDGYHLTRAQLSSMPDPVNAHARRGAVFTFDGDSFHKLVISLREPLRADTTPIYAPSFDHAVKDPKPDDIVIQPYHRIIVFEGNYLALDRSPWNYAARLMDELWFVDVDFDVARKRLITRHVMAGIAKDEVEADRRARENDLVNGKEIVDFRLPVDELIISREDDKWIHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>E3QX37</accession>
    <name>E3QX37_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10569</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697392">
        <property type="protein sequence ID" value="EFQ35425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099445.1">
        <property type="nucleotide sequence ID" value="XM_008101254.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QX37"/>
    <dbReference type="GeneID" id="24415934"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10569"/>
    <dbReference type="HOGENOM" id="CLU_2333505_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="98" mass="10713" checksum="8338B80B4EDC7595" modified="2011-01-11" version="1">MKPEFTEPPDLEVKVRKEEDAGAGQLRPGVAWCIEADLDLGGVADTKLATIADWEARWATVKKPKPAPKTKSREPKVLKVTENTPCGFPGSTYTTCNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXQ1</accession>
    <name>E3QXQ1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">ATP-dependent RNA helicase DHH1</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">ATP-dependent RNA helicase dhh1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">GLRG_10798</name>
    </gene>
    <organism evidence="23">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">P-body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="GG697397">
        <property type="protein sequence ID" value="EFQ35654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099674.1">
        <property type="nucleotide sequence ID" value="XM_008101483.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXQ1"/>
    <dbReference type="STRING" id="645133.E3QXQ1"/>
    <dbReference type="GeneID" id="24416163"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10798"/>
    <dbReference type="eggNOG" id="KOG0326">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_30_0_1"/>
    <dbReference type="OrthoDB" id="10265785at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098562">
        <property type="term" value="C:cytoplasmic side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010494">
        <property type="term" value="C:cytoplasmic stress granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042149">
        <property type="term" value="P:cellular response to glucose starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006995">
        <property type="term" value="P:cellular response to nitrogen starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000290">
        <property type="term" value="P:deadenylation-dependent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036267">
        <property type="term" value="P:invasive filamentous growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045900">
        <property type="term" value="P:negative regulation of translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033962">
        <property type="term" value="P:P-body assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045727">
        <property type="term" value="P:positive regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007124">
        <property type="term" value="P:pseudohyphal growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010603">
        <property type="term" value="P:regulation of cytoplasmic mRNA processing body assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000749">
        <property type="term" value="P:response to pheromone triggering conjugation with cellular fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034063">
        <property type="term" value="P:stress granule assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd17940">
        <property type="entry name" value="DEADc_DDX6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000114">
        <property type="entry name" value="ATP-dependent RNA helicase DDX6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000364">
        <property type="entry name" value="ATP-dependent RNA helicase DDX6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47960">
        <property type="entry name" value="DEAD-BOX ATP-DEPENDENT RNA HELICASE 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 17 22" id="KW-0347">Helicase</keyword>
    <keyword evidence="6 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="5 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="10" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="21">
        <location>
            <begin position="47"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="19">
        <location>
            <begin position="78"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="20">
        <location>
            <begin position="258"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="15"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="426"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="16">
        <location>
            <begin position="47"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="450"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="18">
        <location>
            <begin position="500"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="519"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00038316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00040210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00040448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="EFQ35654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="530" mass="59078" checksum="782889D88B04FCC8" modified="2011-01-11" version="1">MAEALADKLKATNLSDGAASEDWKKSLKLPAKDNRQQTEDVTNTKGLEFENFQLKRDLLMGIFEAGFERPSPIQEEAIPVALTGRDILARAKNGTGKTAAFVIPALEKINPKVSKIQALILVPTRELAMQTSQVCKTLGKHLGINVMVTTGGTGLRDDIIRLQDPVHIVVGTPGRILDLAGKNVADLSECSMFIMDEADKLLSIEFTPVIEQLLQFHPKDRQVMLFSATFPLSVKDFSDKNMVSPYEINLMDELTLRGITQYYAFVEEKQKVHCLNTLFSKLQINQSIIFCNSTNRVELLAKKITELGYSCFYSHAKMAQQARNRVFHDFRNGVCRNLVCSDLLTRGIDIQAVNVVINFDFPKNAETYLHRIGRSGRYGHLGLAINLINWDDRFNLYNIEKDLGTEIQPIPASIDKSLYVYENPESIPRPVSNFKTSQPGRGEHQHQHQHQQQQQPMQDQQPLLQGGPPPGNWQTQQPQQSGQQNGYQGGGRGRGRGRGGYRGQNRGGYGGGGRGRSQGQGHPQPQGQMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QY61</accession>
    <name>E3QY61_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_10994</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697400">
        <property type="protein sequence ID" value="EFQ35799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099819.1">
        <property type="nucleotide sequence ID" value="XM_008101628.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QY61"/>
    <dbReference type="STRING" id="645133.E3QY61"/>
    <dbReference type="GeneID" id="24416359"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10994"/>
    <dbReference type="eggNOG" id="ENOG502QSKG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010595_1_2_1"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF31">
        <property type="entry name" value="LAEA-LIKE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G01930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ35799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="359" mass="39863" checksum="EC67F4474D74FABA" modified="2011-01-11" version="1">MSDNATTTAATGASSPPNADVSVPQAAVHDNNVVIAVDDDVDDGLSVSHASVATSTTSLAASVRDYRVENGRTYHAYKDGKYLVPNDEQELDRLDLQHEIFLRSFDNRLGTAPPNDPDAKVGRVLDVGTGTGLWAIDFGEEHPEAEVLGIDLSPPPSSFVPPNVRFVVDDAEEPWEYSQPFDYIHSRLMTGSIRDWKKYVKNCFENLAPGGYLELTEGDVIPVSDDGTLTKDTSIVKAVSLWTQGMALLDTPFEAVGRLEGVMKDAGFEDVQVKRFKWPTNSWPKDPKYKELGMLNYENISPNWEGFLMAPLTRALDWTKEEVLVLAMGARKDTANRNIHAYYQMWSIHGRKPLKTEEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYD8</accession>
    <name>E3QYD8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cell wall protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11067</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697402">
        <property type="protein sequence ID" value="EFQ35876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099896.1">
        <property type="nucleotide sequence ID" value="XM_008101705.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYD8"/>
    <dbReference type="STRING" id="645133.E3QYD8"/>
    <dbReference type="GeneID" id="24416432"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11067"/>
    <dbReference type="eggNOG" id="ENOG502RW3X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090704_1_0_1"/>
    <dbReference type="OrthoDB" id="2422134at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021054">
        <property type="entry name" value="Cell_wall_mannoprotein_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38123">
        <property type="entry name" value="CELL WALL SERINE-THREONINE-RICH GALACTOMANNOPROTEIN MP1 (AFU_ORTHOLOGUE AFUA_4G03240)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38123:SF6">
        <property type="entry name" value="CELL WALL SERINE-THREONINE-RICH GALACTOMANNOPROTEIN MP1 (AFU_ORTHOLOGUE AFUA_4G03240)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12296">
        <property type="entry name" value="HsbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180024" evidence="1">
        <location>
            <begin position="24"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="227" mass="22361" checksum="E47A91AC8F2D7270" modified="2011-01-11" version="1">MLGSKVLAAALQVLAITAGPVLVARQRDVITGAIGMVQGSLQKLDTAIKQLSATDPNTAVGVLNAAQGAQTTLEKAATQISGADDLSLIGALGLQQTAGDLVTQVQTTLGDLEQKKPVFDQLGVSSVVADSLQQQKEGSGQLSEMLLSKIPAIARPIAQKSTGQLDTAIDSAIATFRSPAAAKAVPPAVPAAPAAPAAPIVAPAVSKRAASPAAPAGAAAAVGAAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYQ9</accession>
    <name>E3QYQ9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DJ-1/PfpI family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11141</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697406">
        <property type="protein sequence ID" value="EFQ35997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100017.1">
        <property type="nucleotide sequence ID" value="XM_008101826.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYQ9"/>
    <dbReference type="GeneID" id="24416506"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11141"/>
    <dbReference type="eggNOG" id="ENOG502SQ0U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_44_8_1"/>
    <dbReference type="OrthoDB" id="543156at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052158">
        <property type="entry name" value="INH-QAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130">
        <property type="entry name" value="ARAC-FAMILY TRANSCRIPTIONAL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130:SF7">
        <property type="entry name" value="DJ-1_PFPI DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1/PfpI" evidence="1">
        <location>
            <begin position="48"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="217" mass="24529" checksum="3DC39E41084FE297" modified="2011-01-11" version="1">MLEAVQLGDIVGIDMFGNLSRKYYNKVKDYDPEFAQWADPPIEMDFFYISSTLAPAEMTPGLKFVPNVTYDDCPRDLDLVLIGGPMPDHRPPSADRFMKEAFPKTKVWLTTCTGSLWLASAGVLKGKIATTNRELLKFARETHPETEWLDKRWVVEEKEYEGEGKGELWTAGGAGASLSMIIKYLNKNFDPGFVQKLGIDVIAFEELALNQFYKTSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZ19</accession>
    <name>E3QZ19_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Crh-like protein</fullName>
            <ecNumber evidence="15">3.2.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">GLRG_11251</name>
    </gene>
    <organism evidence="21">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Dual chitinase/transglycosylase that plays a role in cell wall architecture. Chitinase and transglycosylase activities are coupled. Required for the polysaccharide cross-linking at the septa and the cell wall. More specifically, transfers chitin to 1,6-beta-glucan in the cell wall.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
            <topology evidence="2">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the glycosyl hydrolase 16 family. CRH1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.2.-.-" evidence="15"/>
    <dbReference type="EMBL" id="GG697409">
        <property type="protein sequence ID" value="EFQ36107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100127.1">
        <property type="nucleotide sequence ID" value="XM_008101936.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZ19"/>
    <dbReference type="STRING" id="645133.E3QZ19"/>
    <dbReference type="GeneID" id="24416616"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11251"/>
    <dbReference type="eggNOG" id="ENOG502QVQI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040459_0_0_1"/>
    <dbReference type="OrthoDB" id="4781at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.200:FF:000159">
        <property type="entry name" value="Glycosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018371">
        <property type="entry name" value="Chitin-binding_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017168">
        <property type="entry name" value="CHR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF22">
        <property type="entry name" value="GLYCOSIDASE CRH2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037299">
        <property type="entry name" value="Glycosidase_CRH1_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00026">
        <property type="entry name" value="CHIT_BIND_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="7 15 20" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="8 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 18" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="18">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179002" description="Crh-like protein" evidence="18">
        <location>
            <begin position="20"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="19">
        <location>
            <begin position="15"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="347"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="370"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="17">
        <location>
            <begin position="387"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="16">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="16">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00093308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR037299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR037299-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EFQ36107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="460" mass="47987" checksum="132DAC2E0441C714" modified="2011-01-11" version="1">MLSILPLGLALLGTSTVLAQTPPSCSLTNKCPEDAPCCSQYGQCGTGAFCLGGCDPRMSFSLDACVPAPVCQDKKMPMNSLDKIVDISKYLGDPSKADWVAQGEPALYNKEAVLLTMPAKSVGTVLASTTYMWYGNVKATIRTSRGPGVVTAFILYGDVKDEIDYEWVGADLEMSQTNYYFQGIPKYDQSGNISLSDTFSNWHTYEISWTPDEIQWLVDGQVGRTKKRSDTWNATAQQWDYPQTPARVQLSIWPGGADTNAKGTIDWAGGPINWDSEDIKNAGYYYAMVKDVEISCFNANTPPGTNNKKSYYYNNIRSTNDTVVDSDKGTILQSFLGTGLDMDAGATTASGSAAKPTVTAATIPGGSNAGPGNDHSSNDNSSPSSGAGSGSGSGSGSGDSGSGSGSGSGSSSCGAGGFSQDCNSNGNSGSNNTSDGACRKSSLGASAFAALVAASALFWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZC0</accession>
    <name>E3QZC0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HAUS augmin-like complex subunit 6 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_11353</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697414">
        <property type="protein sequence ID" value="EFQ36208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100228.1">
        <property type="nucleotide sequence ID" value="XM_008102037.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZC0"/>
    <dbReference type="STRING" id="645133.E3QZC0"/>
    <dbReference type="GeneID" id="24416717"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11353"/>
    <dbReference type="eggNOG" id="ENOG502S4RN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013984_0_0_1"/>
    <dbReference type="OrthoDB" id="5575722at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028163">
        <property type="entry name" value="HAUS_6_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14661">
        <property type="entry name" value="HAUS6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HAUS augmin-like complex subunit 6 N-terminal" evidence="2">
        <location>
            <begin position="46"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="465"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="611"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="663"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="723"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="670"/>
            <end position="680"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ36208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="746" mass="83570" checksum="841969AFC9DB6016" modified="2011-01-11" version="1">MATLPPNSLLARSRQTRSGPIAKSSAAPIAPSIASNPVSTTHLSLFLTNLRLLDLPSYPDWPGLDAQTFSVQKKRIHCVEWTLYQLFVLWDPEEARNKLQPFFPPRDHVQSLNLRAALLRSLDQAKKNGVLGRDAVIRKTMLDECKGERLEEVLAVFSSVVLKKIVAQVSEAEGEYPAVAQQLALEDRGYNTERTELIPLALAHRASIANAMRRKNDARKQYSGLAELLNLKDVAITRRREEIKAASELSKGRDVPDDVKFDTWRMVRNNWAGNEQWMETLLYGDSNARKDGLLSVSFDRVWRSLQSGRLSELEDHGKGLLEQLDDRVRTQRERLAQWRHFQAKMFGNRPNLTTNPAPQPKRIKRGVNLAFDLHENLHLGQMSWRKQLAKKSPSLTRDYASLLADCEAELAQVGSAPLIDLSKVLGPRTRQPEKPDINACARESLGEETVSELSELEDDIQGLNTGLRRLSPHDDASQPGSPPCRPALTLSHETRRPIGIKPSSLSPPLLPPDSHTELSIPPPTPPLPEEEGVTEKPPSRLPSPSPPERERKGFSVTFEGEDSSPEPPKSPTQELADKILNDMDNASPSPIKRPKPRHTLSLAERTRLSMVRSSRGIRYDPDDEEEDDALSLQPSLASINRQMKDITINVTDEDDLVSRTRRSMAGFEASRQKAQLDRQRSLKKSRAQPKTVPVVEEETLQLDPDASILAEELMTVEDMEAVFRSRPRIKTSPAPSPSRKSLQDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZW0</accession>
    <name>E3QZW0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_11566</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697422">
        <property type="protein sequence ID" value="EFQ36398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100418.1">
        <property type="nucleotide sequence ID" value="XM_008102227.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZW0"/>
    <dbReference type="GeneID" id="24416930"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11566"/>
    <dbReference type="HOGENOM" id="CLU_1532428_0_0_1"/>
    <dbReference type="OrthoDB" id="10333431at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ36398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="175" mass="19422" checksum="2B5BBA1C9118C22B" modified="2011-01-11" version="1">MEQNQLLLLQAPEQWPLWPDLDASFSPDFFTSHELQANVLQNHETATLESYRLQPTPNLTVADFPLSTPLYLDAGIDLGFGWCMGPATDDFNIPASYGGLSRHNPHFGSTTGKVTEPPCFPVLDGALVSVHTWDLPKATSNNREHTKGIEGRTSLTSLLNHPNLHYLSKRPLDCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0R3</accession>
    <name>E3R0R3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11850</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697477">
        <property type="protein sequence ID" value="EFQ36701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100721.1">
        <property type="nucleotide sequence ID" value="XM_008102530.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0R3"/>
    <dbReference type="GeneID" id="24417213"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11850"/>
    <dbReference type="HOGENOM" id="CLU_2704662_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="73" mass="8145" checksum="72A736EA82A88B62" modified="2011-01-11" version="1">MAITKTLSSRTSGLRVVKKRGNYSSTDQAGERQARRLSLMARNRKAGKQRANNDDTGSGLAVSRAYGFWRLDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q292</accession>
    <name>E3Q292_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_00337</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089213.1">
        <property type="nucleotide sequence ID" value="XM_008091022.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q292"/>
    <dbReference type="GeneID" id="24405702"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00337"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_4_2_1"/>
    <dbReference type="OrthoDB" id="3639251at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000065">
        <property type="entry name" value="Putative MFS pantothenate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF15">
        <property type="entry name" value="TRANSPORTER SEO1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="191"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="311"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="356"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="388"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="421"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ25193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="447" mass="50562" checksum="9C238D73FBDA096E" modified="2011-01-11" version="1">MADNTVPRQKWWKIQWYSDDDTPEERKFIVKLDLIIVPYAVLAYWVKYIDNAYVGGMKEELGFKGNELVELQTMYTVGAVVGMVPFMFLFTYIPMYWTIPAMDILWGLFTLLQYRANSFGELAAYRFLVGFFEAAFFPAMHYVFGSWYRGHEIARRGGIFYTGLNLGTLTAGLIAAGALHRLEGVNGMAGWRWMYIICAIITIPVGILGYFLLPGTLEQPNRWILNDHDLKVARARLERGGHVTRGKFKLGHLKNIFLSPQFWTVVLVDILFWNAGIHKSTGSFLLWIKSLGRYSPAQVNEMGTIAPAMGILYNLVACFLSDLVLGPAWAITFSSLWNVTGLIMLVVWDVPESAKWFAFSTMYWANALSSVLHGWVNTILRDSPEQRSFTLVMITIIAQSSTAWTPLLTFPTVEAPSYPKGFSFCLGCAVALIAATHVLNLYIKRKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q293</accession>
    <name>E3Q293_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl hydrolase family 16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00338</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089214.1">
        <property type="nucleotide sequence ID" value="XM_008091023.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q293"/>
    <dbReference type="STRING" id="645133.E3Q293"/>
    <dbReference type="GeneID" id="24405703"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00338"/>
    <dbReference type="eggNOG" id="ENOG502S1W9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019533_3_1_1"/>
    <dbReference type="OrthoDB" id="192832at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02182">
        <property type="entry name" value="GH16_Strep_laminarinase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF60">
        <property type="entry name" value="GRAM-NEGATIVE BACTERIA-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26113">
        <property type="entry name" value="GH16_XgeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180125" evidence="1">
        <location>
            <begin position="20"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="2">
        <location>
            <begin position="18"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ25194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="284" mass="31031" checksum="6F0F4365FC1195A4" modified="2011-01-11" version="1">MHPKSLLSTLLVLLPAASAWDSPNYSGFNRIWQDTFAGAAATGVNEANWQIITNINVNNEIQQYTTSRNNLQLSGGSTVQIIPQKDASGRWTSGRIESKYTFTPAAGRVTIAEGLIRFGDTPIANKKGIWPAFWILGAAIRNGVSWPRCGELDILETVNGQLTGYGTVHCDTYPGGACNEPNGIGSATAIPDQGWHTWRMQWDRRSNNWQTETITWFRDGQQFHQISGARIGSEGIWNSLAHAPLYFILNVAVGGNWPGNPDGSTVGGWGSLMETAYVAVYQSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2X3</accession>
    <name>E3Q2X3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Nucleoporin NUP188</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_00096</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the Nup188 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ24952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008088972.1">
        <property type="nucleotide sequence ID" value="XM_008090781.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3Q2X3"/>
    <dbReference type="GeneID" id="24405461"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00096"/>
    <dbReference type="eggNOG" id="ENOG502QQFV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001029_0_0_1"/>
    <dbReference type="OrthoDB" id="102511at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044611">
        <property type="term" value="C:nuclear pore inner ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006405">
        <property type="term" value="P:RNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018864">
        <property type="entry name" value="Nucleoporin_Nup188_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044840">
        <property type="entry name" value="Nup188"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041634">
        <property type="entry name" value="Nup188_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048883">
        <property type="entry name" value="Nup188_N-subdom_III"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31431:SF1">
        <property type="entry name" value="NUCLEOPORIN NUP188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31431">
        <property type="entry name" value="NUCLEOPORIN NUP188 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18378">
        <property type="entry name" value="Nup188_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10487">
        <property type="entry name" value="Nup188_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21093">
        <property type="entry name" value="Nup188_N-subdom_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21094">
        <property type="entry name" value="Nup188_SH3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="6" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Nucleoporin Nup188 N-terminal" evidence="10">
        <location>
            <begin position="177"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoporin Nup188 N-terminal subdomain III" evidence="12">
        <location>
            <begin position="759"/>
            <end position="1147"/>
        </location>
    </feature>
    <feature type="domain" description="Nuclear pore protein Nup188 C-terminal" evidence="11">
        <location>
            <begin position="1449"/>
            <end position="1815"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00040174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF10487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF18378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF21093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ24952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1822" mass="201645" checksum="0509D21982CEF6C1" modified="2011-01-11" version="1">MAQVADSHYFPPLEECLNGDTIIISWKLIAVALSDKDDARRKSEAVVQFLQDNYVRSLIKDPATAFAPPGDSTKSNFETRTAAIHVTPQPNEKFDIKVIKEDAQWLSKNAKVNLIAALRATVVEFQMRPASHLTGTLSSQDIINLQEASGVANIQSSALVPIAGAAQDAETIWADFEKEESRRQRIFQTYLSERRHFLMTAALVQETVLYTQPSAPASITVDKPSMQTQLIAANDRPKYLDNLLTTYLQYVTEAIGRLAEGLDAVVEDKNLLGDELELEWMRTALTEVVHALTVVFQSIDGNGDAFVPSAVVGQWFTLMENYGFLNGITAPTDMIASLIMPLRSLICAISIKLLNPSRSIECLSEEAPEYRGDEDPYITAPAVLEQVHNAILAAANADCESQSPVIFAWTVVVHRMFYSHHDRIEKRDALQNQRSQETFEAGVLIRPTPSRRLSAGSIVSLDGKSFDIFLNNAGLDKDLQVVEQLAVAVTSNGRAYEVLSEMALAIGGSSDGAFSSLLSSRIRLAYVDFLKATYPLVGYQSESVTSLLSVLGAGRQYWDLSRPALHPSNDILAEFLQDATAMEYYFHQALNRYPFELLPFLNICRTLAHCVVADDRMDTVVNLLRKTPTLTFILPDDYQQYELAQEEDNTNTFYLLEDIPLFTPATAWNRRTRHDDAFRIPAETVGRFVTDTGRVVLMEYEHSALALLGKRLEVQLAPETYRSELDAFQPEETAETIALFAVLLRAEVLKSEKQGLSGETSLKSGLDLLEEIGKHISGNKDLVAVVCETMDAYMQDEKATEGQGIAVLNSCVQFLHAILPLCPTRVWSYLARCELLNSEAQAGKLAKMTGNLDLVGDRYELLLSAVRLFASLIDSVKSSAVQRKSGNKLVGRQKVSNNVWLGVADKVLGKVSLAIAQAAVDVFETSSTWRFGSELHKTLLIRHVVPVMDHVILHTYGMGDRESSETLTACLEPAASYIIDAFLSPSTGSLRFQPLLTTLVNGLQLPDSTLYQGRLASAQEQLVSALQFTTTLLRVANYLERSSEIFEDHLFKTSSILARLCAICEQFRRPALLLLEALVLSAAKAHDDPPSLLGYLGPLLSRSFIQVLSRLDKPFLVAEDVQTTWKFFSTIVQNRQQWLSNCLLTGKTPRDALKGAKKDASSTPNSVLATAFTKLKNIKELDIDEALRILDFVASSQNHWPWTIFTMQKDSSFLDSLRLYVKDLSSFTVTSKTDAVKAAIDAKMAAYIAEIFAMQLYHLRQMAGADTFAKSLVADLDYYLRDGVEVSSYNNSLHSNFAKNFTSKYPGVSLEAFKRTALRPGELGRSYFYDLESATEMLSFDPGWHGRRNNGFRHEMEIANANLSLVDAQISLFHAWEFLLLELSSSLPDNDNIAKQMLQVAQQCLEANRSNQGPENIFMRIVEERADLSLLLVQRLVGRPISSHDVNQILGTLFTIISAVEEPFSPGSISYYRTMLKTIYVTLRAYSVADKKGLGTSKNGGEGFSVTLTQTVLNVLDRVVAKGFRTLVALVHDSEAAVAPEDLALLTALLQACLNMPMMDQCQTQILNIMASYDAMHAATSLFSWADKLAINGDPIYGELSLLFLLELSTLPAVAEQMACDGLLSHLTSAGITNFMRRGNISPFSEAIGPQRCYSIWVKGVLPLLLNLLTALGGTVAPEIGYVLNQFPLLLKSSIDRFEAPGASRTASREAPHYVTLLSVAEVHSLALLTRVIAALRTANTRDIPEIQWDASSLLENVDFWLSSRKLLRDRLLPLGQREVEWKSTKIGTADESGQPGNVLESKVLSQLEAVRDVLSEDLEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q318</accession>
    <name>E3Q318_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Snf5/smarcb1/ini1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_00141</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF5 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ24997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089017.1">
        <property type="nucleotide sequence ID" value="XM_008090826.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q318"/>
    <dbReference type="STRING" id="645133.E3Q318"/>
    <dbReference type="GeneID" id="24405506"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00141"/>
    <dbReference type="eggNOG" id="KOG1649">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018784_0_0_1"/>
    <dbReference type="OrthoDB" id="515064at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000228">
        <property type="term" value="C:nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006939">
        <property type="entry name" value="SNF5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10019">
        <property type="entry name" value="SNF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04855">
        <property type="entry name" value="SNF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="438"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="547"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="716"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="453"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="477"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="550"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="572"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="590"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="614"/>
            <end position="631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ24997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="737" mass="81876" checksum="B80DCF563F4BDBA6" modified="2011-01-11" version="1">MAAQPSTFTPTAAGATASSSASTSASAANDHDGTPQSAAAKALPVRNRDSFNKLQVERYVTRDWYHSVAMKDAQERFEKDMQQMRDKIDDYNIVKTQRVYFPPSKLYGEGYRGFGNGYTDIDPRMRAPFPAQVIYPSQKPRPGKRQSHPLRWKKKELKKQAEQHEELVPVRIDVDWEKIKLRDTFTWNLHDRIIPAELFAQHLVEDLGVPLDAQHKPVLDQVILQMRDQLNDFYPLVFSEEDALDPELPYSAYKNDEMRVLIKLNVTIGGVTLVDQFEWDINNPLNSPEEFAASMTRDMALSGEFTTAIAHSIREQCQLFTRSLYSVGHPFDGRPVEDPDLVAAFLPSPLPSVFRPQQQAKDYAPYLYELSDADLERNEVIFSRELRRQKRSINRRGGPQLPDLKERQRTIRTLLVSSVLPGAAPNIEESTLYKRVAGAPNTRKRPGARDGEVSDSDDSEDSGPDSPGVSQLGGGTARTRGLRGAASAAQQRITNLGRSETPEASIIHHHETRRNIGRTLRDTRDETEEPSQLIVTLKVGKDKLRRLLQTPRSRVTPSGSQTPSTPAHTRIPSAAAAAAAANSMPPPSTPASNSQTLPTTLGTPLPQGQIGRQPAPPPVAGQPPPPPPPPPEWLKDCLQQLKNTYTFDNFEGMMKYSAINPDTEMPISVPAGSQPPEGAKWMFLPRIRCLDCPGKLYTPGPEMTAGNFEVHLRNKQHRQKVDARVGKDTSPAAIGTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3H2</accession>
    <name>E3Q3H2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Endoplasmic reticulum transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">GLRG_00718</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Endoplasmic reticulum membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the BCAP29/BCAP31 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089594.1">
        <property type="nucleotide sequence ID" value="XM_008091403.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3H2"/>
    <dbReference type="STRING" id="645133.E3Q3H2"/>
    <dbReference type="GeneID" id="24406083"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00718"/>
    <dbReference type="eggNOG" id="KOG1962">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087648_0_1_1"/>
    <dbReference type="OrthoDB" id="435607at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070973">
        <property type="term" value="P:protein localization to endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008417">
        <property type="entry name" value="BAP29/BAP31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040463">
        <property type="entry name" value="BAP29/BAP31_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041672">
        <property type="entry name" value="Bap31/Bap29_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12701">
        <property type="entry name" value="BCR-ASSOCIATED PROTEIN, BAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12701:SF20">
        <property type="entry name" value="ENDOPLASMIC RETICULUM TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05529">
        <property type="entry name" value="Bap31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18035">
        <property type="entry name" value="Bap31_Bap29_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 11" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="BAP29/BAP31 transmembrane" evidence="13">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="Bap31/Bap29 cytoplasmic coiled-coil" evidence="14">
        <location>
            <begin position="162"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="164"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU367026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF05529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF18035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EFQ25574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="211" mass="24337" checksum="DC8A7B0F75220889" modified="2011-01-11" version="1">MTLYYTLVFVLLMAEMGLFMLLIVPLPFTVKRKLFTFISESPIVAKVQYWMKITFVFILILFIDSVNRVYRVQVELALATEKQNSGGAAVMGHERLEVQARKFYSQRNMYLCGFTLFLSLILNRTYVMILEVMRLEDKVRSYEGTKGNAKESEKLAVAGEPGEIARLRKELEQKNRDIETLKKQSAGLHKSYDELSDQYAKTQPQGNKKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3U7</accession>
    <name>E3Q3U7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">peptide-methionine (S)-S-oxide reductase</fullName>
            <ecNumber evidence="2">1.8.4.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Peptide-methionine (S)-S-oxide reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_00843</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-methionyl-[protein] + [thioredoxin]-disulfide + H2O = L-methionyl-(S)-S-oxide-[protein] + [thioredoxin]-dithiol</text>
            <dbReference type="Rhea" id="RHEA:14217"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>[thioredoxin]-disulfide + L-methionine + H2O = L-methionine (S)-S-oxide + [thioredoxin]-dithiol</text>
            <dbReference type="Rhea" id="RHEA:19993"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58772"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MsrA Met sulfoxide reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.11" evidence="2"/>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089719.1">
        <property type="nucleotide sequence ID" value="XM_008091528.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3U7"/>
    <dbReference type="STRING" id="645133.E3Q3U7"/>
    <dbReference type="GeneID" id="24406208"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00843"/>
    <dbReference type="eggNOG" id="KOG1635">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031040_10_2_1"/>
    <dbReference type="OrthoDB" id="77405at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008113">
        <property type="term" value="F:peptide-methionine (S)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1060.10:FF:000006">
        <property type="entry name" value="Peptide methionine sulfoxide reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1060.10">
        <property type="entry name" value="Peptide methionine sulphoxide reductase MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01401">
        <property type="entry name" value="MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002569">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036509">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00401">
        <property type="entry name" value="msrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43774">
        <property type="entry name" value="PEPTIDE METHIONINE SULFOXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43774:SF1">
        <property type="entry name" value="PEPTIDE METHIONINE SULFOXIDE REDUCTASE MSRA 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01625">
        <property type="entry name" value="PMSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55068">
        <property type="entry name" value="Peptide methionine sulfoxide reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptide methionine sulphoxide reductase MsrA" evidence="7">
        <location>
            <begin position="40"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ25699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="207" mass="23169" checksum="7A450FBEB9142C3D" modified="2011-01-11" version="1">MVLNFISRLARPFASTATMSAAPSSSAAGAGPTIPEDAQKATIAAGCFWGVEHLYRKHFQGKGLVDARVGYIGGDLSNPTYRAVCGGDTGHAEALQIVFRPKDVSYRQLLEFFYRMHDPTTANRQGPDTGPQYRSAIFFHDEEQERVAREVTRLANEKWYKGKIVTQIIPAGQWWDAEQYHQLYLNKNPSGYECPSHFLRTFPPLQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3V5</accession>
    <name>E3Q3V5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="8">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_00851</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the peptidase C12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="8"/>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089727.1">
        <property type="nucleotide sequence ID" value="XM_008091536.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3V5"/>
    <dbReference type="STRING" id="645133.E3Q3V5"/>
    <dbReference type="GeneID" id="24406216"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00851"/>
    <dbReference type="eggNOG" id="KOG1415">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054406_0_2_1"/>
    <dbReference type="OrthoDB" id="427186at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09616">
        <property type="entry name" value="Peptidase_C12_UCH_L1_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.532.10">
        <property type="entry name" value="Peptidase C12, ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001578">
        <property type="entry name" value="Peptidase_C12_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036959">
        <property type="entry name" value="Peptidase_C12_UCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589:SF17">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01088">
        <property type="entry name" value="Peptidase_C12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00707">
        <property type="entry name" value="UBCTHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52048">
        <property type="entry name" value="UCH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4 8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UCH catalytic" evidence="9">
        <location>
            <begin position="15"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ25707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="251" mass="27251" checksum="B20F30B0746ED900" modified="2011-01-11" version="1">MPADGVYYSPTGKKTFIPLENNPDVFTSLVHDLGVSPSLGFFDVYSLDEPALLDLVPRPALALIFIAPAPMYYQVRAADGTRIAKEDGVTYRGAGPGEPVTWFRQTIGNACGLYALIHAVGNGEARTLVTEGSLLDGLLKEAEPLRWEARADVLYKSEELEEAHMKAARKGDTAPPPAEERPGYHFIAFVKGKDGHLWELEGGSDGPVDRGLLEEGEDMLSEGALEKGVKKFLNYADGNLEFSIVALAEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q413</accession>
    <name>E3Q413_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Fungal specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_00909</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089785.1">
        <property type="nucleotide sequence ID" value="XM_008091594.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q413"/>
    <dbReference type="STRING" id="645133.E3Q413"/>
    <dbReference type="GeneID" id="24406274"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00909"/>
    <dbReference type="eggNOG" id="ENOG502SIT3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004083_2_0_1"/>
    <dbReference type="OrthoDB" id="3989227at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF50">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="68"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="99"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="142"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="766"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="863"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="155"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="786"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="863"/>
            <end position="901"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ25765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="958" mass="107951" checksum="24A79C16DF5A423B" modified="2011-01-11" version="1">MEIFPPSQMSNPATPAHAMSANPHQHSPNSPPTIHEYTSLARHGATSISPDQPVAMTPSGQPALNPRSCVTCRKRKVRCDKQMPCSNCRRAVIQCIFPAPGRAPRRPRPKDPNAPPKNSSEREVELMKRLRKLEGIVEELSGQIEVESGPGSNGGRHNTSTGNSPETFTNEVGSDRIASTQSNSTPTSAPREAASPNRMNTNSDPKRPQDKQTGLNREFGRLVLHDKGKSSRYVSSAFWSKLNDELDELREETRVLGADTDDSDIEDTPDHSPQQSVDAATDHHAFILGYRSSDVDLRKLHPLPSQIPFMWQVYQENVEPLLKILHIPTMEKLIRNMRRSIDELTPGNEALLFSIYYAAITSMEGEEVEKNFGSKKETMLSQFRFALEQALAKANFLNTSDMVVLQAFVLFLTLVRREDDTRFCWTLTGLAIRIAQGLGIHRDGTNFDLPPFETEMRRRLWWAICALDLRSAEELGSDLTIIDRSFDTELPSNVNDSDIEPDMTEVPRSRRGKTDCAVSLVRYEICALSRRLHTAGSAMAGVCPRDASPSLEEHERMLIEVYDRVEDKFLQHCVTQEDPLFWMAGMIARVIMAKMSLVIYQPMLFPGNGHELSNGIRDRLFLSAIEIVEYNYILNTDPRCKQWRWLFQTYRQWHAIAYILMEAGRRPWSATSERGWEAVNNTMRFDRDPAEISRMADHMAVWVPLRKLSAKATKHREAEILRLRSDPEAAPQLDVDDRMNPIPARLGPVPGMEVQHAQIRARWRTLVRTESSSPVQPAAGRPKQMQPAQNAPSGAPASQPNQRARIPASVRPPREPEFIDTVMMARGFNPNHIWEYLYPAAETMAADPNNTLFPPAASQSMMSSDVQCSTGSGQNMEAEQRQRQQAITATSQPRASSSVAENQPPWLWSDPFTSINDLPGDSMDVNMDSLEDFNWQNWQESIKGLEMDPDNMPLKGAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q487</accession>
    <name>E3Q487_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NLI interacting factor-like phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00543</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089419.1">
        <property type="nucleotide sequence ID" value="XM_008091228.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q487"/>
    <dbReference type="STRING" id="645133.E3Q487"/>
    <dbReference type="GeneID" id="24405908"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00543"/>
    <dbReference type="eggNOG" id="KOG1605">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020262_2_0_1"/>
    <dbReference type="OrthoDB" id="277011at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034198">
        <property type="term" value="P:cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904262">
        <property type="term" value="P:negative regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009651">
        <property type="term" value="P:response to salt stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000043">
        <property type="entry name" value="General stress response phosphoprotein phosphatase Psr1/2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011948">
        <property type="entry name" value="Dullard_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02251">
        <property type="entry name" value="HIF-SF_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="2">
        <location>
            <begin position="332"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="53"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="175"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="236"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ25399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="506" mass="54878" checksum="31138E36AC74F6C4" modified="2011-01-11" version="1">MPEKPQSHNPADDITPEIRQNGQSSQDMSKEKVLLAPEEGGNSKKGRSLLHVPSRSSSQRNQSSPTSTGLSGATVSDSRNSIGGRSKESKSSILGRRRNGSVGSHRSGVETEPTNTPGNTLPNSPVNPPQKKKKGGLFALFGCCGVPDNANAIENGDDAVHKLDKLPARPTTAKSRQPTPQEQQQPSSSIRPQIQEKQPQPEQPMSINEAKGKRVSGATTTDDTTVGGDVGDSKQTTAATSSVAAPAITVESTTGQRVEEETYKKDAEEDEAMPDATPVAEVRHQIPPPVEDAPTSQQLPPPPPGPAPNASALDDAALESEQKFLLPPIAPEFKGRKCLVLDLDETLVHSSFKILHQADFTIPVEIEGNYHNVYVIKRPGVDQFMKRVGELYEVVVFTASVSKYGDPLLDQLDIHKVVHHRLFRESCYNHQGNYVKDLSQVGRDLKDTIIIDNSPTSYIFHPQHAVPISSWFSDAHDNELLDLIPVLEDLAKSDVQDVSLVLDVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4A9</accession>
    <name>E3Q4A9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00565</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089441.1">
        <property type="nucleotide sequence ID" value="XM_008091250.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4A9"/>
    <dbReference type="GeneID" id="24405930"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00565"/>
    <dbReference type="eggNOG" id="ENOG502T48W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_146150_0_0_1"/>
    <dbReference type="OrthoDB" id="4847953at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="103" mass="11224" checksum="F47436725F89BE70" modified="2011-01-11" version="1">MFSKKRVSWVGTFNPRRSSTTSTASSSSPSLSPRSPTFSIFSRSGTNSRKGSMASMTTMGNLEENEHLMAEQPKTAAYVPQHAAKSFMSTATSKEIRKNGEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4F8</accession>
    <name>E3Q4F8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UDP-N-acetylglucosamine diphosphorylase</fullName>
            <ecNumber evidence="3">2.7.7.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_00614</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13509"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="EC" id="2.7.7.23"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; UDP-N-acetyl-alpha-D-glucosamine from N-acetyl-alpha-D-glucosamine 1-phosphate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UDPGP type 1 family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.23" evidence="3"/>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089490.1">
        <property type="nucleotide sequence ID" value="XM_008091299.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4F8"/>
    <dbReference type="STRING" id="645133.E3Q4F8"/>
    <dbReference type="GeneID" id="24405979"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00614"/>
    <dbReference type="eggNOG" id="KOG2388">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025603_1_1_1"/>
    <dbReference type="OrthoDB" id="532420at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003977">
        <property type="term" value="F:UDP-N-acetylglucosamine diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04193">
        <property type="entry name" value="UDPGlcNAc_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000075">
        <property type="entry name" value="Probable UDP-N-acetylglucosamine pyrophosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039741">
        <property type="entry name" value="UDP-sugar_pyrophosphorylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002618">
        <property type="entry name" value="UDPGP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11952:SF2">
        <property type="entry name" value="LD24639P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11952">
        <property type="entry name" value="UDP- GLUCOSE PYROPHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01704">
        <property type="entry name" value="UDPGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="73"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ25470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="504" mass="55377" checksum="815306B711080A91" modified="2011-01-11" version="1">MEAIKSALNVDSSKVAATEPSAEQFAQLREKYAKAGQDHVFTFYDDLPTSEKSTLFQQLSGFDPEHINKITDRALNPPKTDDASAQSGLEPLPESATASILDSKPEDIEKWYQSGLDLIGQNKVAVVLMAGGQGTRLGSSAPKGCYDIGLPSHKSLFQIQAERIRKVQELAAKKAGNSSAVVPWYVMTSGPTRGPTEKYFQENNYFGLDKTNVFIFEQGVLPCISNDGKILLESKAKVAVAPDGNGGIYQALVVSDVMGDMRKRGIEHIHAYCVDNCLVKVADPVFIGFSASKNVDITTKVVRKRNATESVGLILLKNGKPDVVEYSEIDKETAEAQDPKQPGILKFRAANIVNHYYSFRFLESIPQWAHKLPHHIARKKIPYADLKSGETVKPEKPNGIKLEQFVFDVFPMLELSKFASMEVRREDEFSPLKNARGTGEDDPDTSKRDIMLQGKRWLEAAGATVTGETTEVGVEVSPLFSYGGEGLEKFSGKEVKAPAVLEIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5E0</accession>
    <name>E3Q5E0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ubiquitin-conjugating enzyme E2 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">E2 ubiquitin-conjugating enzyme 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Ubiquitin carrier protein UBC2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Ubiquitin-protein ligase UBC2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_01051</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="8">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089927.1">
        <property type="nucleotide sequence ID" value="XM_008091736.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5E0"/>
    <dbReference type="STRING" id="645133.E3Q5E0"/>
    <dbReference type="GeneID" id="24406416"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01051"/>
    <dbReference type="eggNOG" id="KOG0418">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030988_13_1_1"/>
    <dbReference type="OrthoDB" id="9993688at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016050">
        <property type="term" value="P:vesicle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd14311">
        <property type="entry name" value="UBA_II_E2_UBC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23800">
        <property type="entry name" value="UBCc_UBE2K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015368">
        <property type="entry name" value="UBA_C_fun"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09288">
        <property type="entry name" value="UBA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="9">
        <location>
            <begin position="4"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="7">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00039884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00041569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00042190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ25907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="236" mass="26404" checksum="EDB3C60B28305274" modified="2011-01-11" version="1">MASPKERRIGKELMDIRADKDNSGVFAYPIDESNLLHLKGSFPAPPDTPYAGGQYEVDIKIPDNYPFKSPIIKFDTKIWHPNVSSQTGAICLDTLGSGWSPVQTIKTALLSLRMLLEFPNPKDPQDAEVAKMMIENPEAFARKAHEWAVKHAGAPPRDFDTTKWKKESAAEAKANDESRYMGYNKELVDRFVNMGFEVDAVVDAFVFVGIDRNNGADYELEEAYMGDITARLLGEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5E1</accession>
    <name>E3Q5E1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">26S proteasome regulatory subunit 4 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_01052</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089928.1">
        <property type="nucleotide sequence ID" value="XM_008091737.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5E1"/>
    <dbReference type="STRING" id="645133.E3Q5E1"/>
    <dbReference type="GeneID" id="24406417"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01052"/>
    <dbReference type="eggNOG" id="KOG0726">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000688_2_3_1"/>
    <dbReference type="OrthoDB" id="10255768at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036402">
        <property type="term" value="F:proteasome-activating activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070651">
        <property type="term" value="P:nonfunctional rRNA decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045732">
        <property type="term" value="P:positive regulation of protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070682">
        <property type="term" value="P:proteasome regulatory particle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031503">
        <property type="term" value="P:protein-containing complex localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000030">
        <property type="entry name" value="26S protease regulatory subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000007">
        <property type="entry name" value="26S proteasome regulatory subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000039">
        <property type="entry name" value="26S proteasome regulatory subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032501">
        <property type="entry name" value="Prot_ATP_ID_OB_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16450">
        <property type="entry name" value="Prot_ATP_ID_OB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7 13" id="KW-0647">Proteasome</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="12">
        <location>
            <begin position="229"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="87"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="99"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00068880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ25908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="451" mass="50033" checksum="0109C8A6EBE65C63" modified="2011-01-11" version="1">MGGGGDGKDDKDKKKEKPKYEPPPRPTTRVGRKKRKAAGTSAAAKLPAVFPTSRCKLRLLRMQRIHDHLILEEEYVENQERLRRAKAAKEGAAIGPEGDVDRMADERGRVDDMRGSPMGVGTLEEMIDDDHAIVSSTTGPEYYVSIMSFVDKDLLEPGASVLLHHKSVSIVGVLTDDADPLVSVMKLDKAPTESYADIGGLEQQIQEVRESVELPLLHPELYEEMGIKPPKGVILYGAPGTGKTLLAKAVANQTSATFLRIVGSELIQKYLGDGPRLVRQLFQVAGENAPSIVFIDEIDAIGTKRYDSTSGGEREVQRTMLELLNQLDGFDDRGDVKVIMATNKIETLDPALIRPGRIDRKILFENPDQNTKRKIFTLHTSKMSLNDDVDLEEFISQKDDLSGADIKAICSEAGLLALRERRMRVQMADFRSARERVLRTKQESEPEGLYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5V7</accession>
    <name>E3Q5V7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tubulin-specific chaperone A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_01349</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
            <location evidence="3">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the TBCA family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090225.1">
        <property type="nucleotide sequence ID" value="XM_008092034.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5V7"/>
    <dbReference type="STRING" id="645133.E3Q5V7"/>
    <dbReference type="GeneID" id="24406714"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01349"/>
    <dbReference type="eggNOG" id="KOG3470">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_130569_0_1_1"/>
    <dbReference type="OrthoDB" id="296187at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048487">
        <property type="term" value="F:beta-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007023">
        <property type="term" value="P:post-chaperonin tubulin folding pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007021">
        <property type="term" value="P:tubulin complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004226">
        <property type="entry name" value="TBCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036126">
        <property type="entry name" value="TBCA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21500">
        <property type="entry name" value="TUBULIN-SPECIFIC CHAPERONE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21500:SF0">
        <property type="entry name" value="TUBULIN-SPECIFIC CHAPERONE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02970">
        <property type="entry name" value="TBCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46988">
        <property type="entry name" value="Tubulin chaperone cofactor A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0493">Microtubule</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU364030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ26205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="126" mass="13847" checksum="E8C3513EDB7A87E3" modified="2011-01-11" version="1">MPPPSQLTVATLSVTRLLKEEISYEKELIQQKAKVATLEAEINDGKPDEDGNREYMLRQLKLAVEETQKIFPSLRTRVEDATAKLEEQIALAESGGAAPEELETAKLALAKGKEEKTYVTDTTGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q606</accession>
    <name>E3Q606_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">Phosphomannomutase</fullName>
            <ecNumber evidence="5 13">5.4.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_01398</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>alpha-D-mannose 1-phosphate = D-mannose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11140"/>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
            <dbReference type="ChEBI" id="CHEBI:58735"/>
            <dbReference type="EC" id="5.4.2.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 13">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the eukaryotic PMM family.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.8" evidence="5 13"/>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090274.1">
        <property type="nucleotide sequence ID" value="XM_008092083.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q606"/>
    <dbReference type="STRING" id="645133.E3Q606"/>
    <dbReference type="GeneID" id="24406763"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01398"/>
    <dbReference type="eggNOG" id="KOG3189">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065642_0_1_1"/>
    <dbReference type="OrthoDB" id="10264771at2759"/>
    <dbReference type="UniPathway" id="UPA00126">
        <property type="reaction ID" value="UER00424"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004615">
        <property type="term" value="F:phosphomannomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009298">
        <property type="term" value="P:GDP-mannose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006013">
        <property type="term" value="P:mannose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02585">
        <property type="entry name" value="HAD_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1240.20:FF:000001">
        <property type="entry name" value="Phosphomannomutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1240.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
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        <location>
            <position position="33"/>
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        <ligand>
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        <location>
            <position position="138"/>
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        <ligand>
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        <location>
            <position position="149"/>
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            <position position="156"/>
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            <position position="194"/>
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        <ligand>
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            <position position="196"/>
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        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:58409"/>
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        <location>
            <position position="231"/>
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        <ligand>
            <name>Mg(2+)</name>
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            <label>1</label>
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        <location>
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        <ligand>
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        <ligand>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
    <sequence length="269" mass="30500" checksum="C70EE8C31989C2D1" modified="2011-01-11" version="1">MATTLPSYPPLEDRPLRNTICLFDVDETLTPARRHASPEMLELLARLRQKCAIGFVGGSDYSKQQEQLGNASTPVTALFDFCFSENGLTAFKLGQPLTSNSFIKFIGEDQYKELVNFALHHIADLDIPIKRGTFIEFRNGMINISPIGRNASTAERLAFEEYDKVHNIRRDFVAKLRERFGHLGLTFSVGGQISFDVFPAGWDKTYCLKHLEDEAKKEGGIKYEQIHFFGDKTFEGGNDYEIYVDERTIGHSVNGPEDTMRVIKETFDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
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        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
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    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
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        </location>
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    </evidence>
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</entry>
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    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
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                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
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                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
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                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
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            <dbReference type="DOI" id="10.1038/ng.2372"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
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    <dbReference type="GeneID" id="24406901"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01536"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ26392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="61" mass="6869" checksum="BD6BFE8CE120A24A" modified="2011-01-11" version="1">MGGAEPKEKRRFGRTAGTKHYGSWPLFGGLFSFNVLNNVQYPSPWFGVVCKWGIIETYGVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6H1</accession>
    <name>E3Q6H1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP synthase complex subunit H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_01563</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
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            <taxon>Hypocreomycetidae</taxon>
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            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090439.1">
        <property type="nucleotide sequence ID" value="XM_008092248.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6H1"/>
    <dbReference type="STRING" id="645133.E3Q6H1"/>
    <dbReference type="GeneID" id="24406928"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01563"/>
    <dbReference type="eggNOG" id="ENOG502SDW5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_122989_0_1_1"/>
    <dbReference type="OrthoDB" id="274752at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019711">
        <property type="entry name" value="ATP_synth_F0_suH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28207">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT H, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28207:SF1">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT H, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10775">
        <property type="entry name" value="ATP_sub_h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="128" mass="14168" checksum="A987939C24CEE8D3" modified="2011-01-11" version="1">MLVQLSRATRVASAVSRLARPSAVQMRGFIAPTVSRRADFVQELYLKELKSYKPSPVKDSDAQGQVQTFSIPQTPKSPEETDLAASLKEYESMAVEVEGQDASAVAANGEPVKHDWLMIEEDEEEPHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6T5</accession>
    <name>E3Q6T5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02393</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090593.1">
        <property type="nucleotide sequence ID" value="XM_008092402.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6T5"/>
    <dbReference type="GeneID" id="24407758"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02393"/>
    <dbReference type="HOGENOM" id="CLU_1570509_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180169" evidence="1">
        <location>
            <begin position="47"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="170" mass="19335" checksum="C630F3073C751713" modified="2011-01-11" version="1">MSLVEHAHALSGPTMAGWPPELSPARPLLGLLVFAFALLLEPPQQGARSWWQKRWREARIITTPAGIKKPSPTGIVPLSYRPYGKHAKLSIKSRLIVMCIFKVLRRHRLMPLAGSTTRAYVFQLLERDYGWRSTERTIHLAVTAAYHCFMACDKHLTSQPSQQAGMMYRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6U3</accession>
    <name>E3Q6U3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02401</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090601.1">
        <property type="nucleotide sequence ID" value="XM_008092410.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6U3"/>
    <dbReference type="GeneID" id="24407766"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02401"/>
    <dbReference type="eggNOG" id="ENOG502T5ES">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098707_0_0_1"/>
    <dbReference type="OrthoDB" id="4072826at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051531">
        <property type="entry name" value="N-acetyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43792">
        <property type="entry name" value="GNAT FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00765)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43792:SF1">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="246" mass="26861" checksum="183FABF73AA04F8C" modified="2011-01-11" version="1">MQSQSSKPDFWLEPLNEKHLQDFHELYSDEQADAWSCQRSTATPEASAVLLTRASTNDAGKPWRVSCAIMSSNHPPPGAHDATPATATTKMIGVVKTTQASAWGLMIGYKLRSNCWGRGYATRAVCAFLNIYWSQSRRAPRGEVFVQQTPNIHEASSHVSRDGASTRDGSTMTRVAGLGGDADEVEITHLVAQVDPDNLGSMRVAEKCGGRLVTVAKESVKVWRFPEKRDMAVWRLDKPSASAGSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q723</accession>
    <name>E3Q723_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_02481</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090681.1">
        <property type="nucleotide sequence ID" value="XM_008092490.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q723"/>
    <dbReference type="GeneID" id="24407846"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02481"/>
    <dbReference type="eggNOG" id="ENOG502T5ZD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_201329_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180157" evidence="2">
        <location>
            <begin position="20"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ26661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="81" mass="8740" checksum="81FEE79178C7787B" modified="2011-01-11" version="1">MKHSVLVLALLFVLGITAAQLPLKPPAYYGAPKKKRMVSRRSGTGPHIARAHTVRAVSVEKPKIADAKKSGKQSEETLVLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7A4</accession>
    <name>E3Q7A4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02562</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090762.1">
        <property type="nucleotide sequence ID" value="XM_008092571.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7A4"/>
    <dbReference type="GeneID" id="24407927"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02562"/>
    <dbReference type="HOGENOM" id="CLU_2196762_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="108" mass="11863" checksum="42342D4094F41D9F" modified="2011-01-11" version="1">MPGAIELFVRPKLQTATPKDHARSPSYENDGHTECSVRWQHFSASPSPAEFALPIFDEQVCTIIIIIKDGRTTPRPISPSAYPAGLMDPDCVSSNMPRYCTATSVSVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7B4</accession>
    <name>E3Q7B4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein YIF1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_02572</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Has a role in transport between endoplasmic reticulum and Golgi.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Endoplasmic reticulum membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Golgi apparatus membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the YIF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090772.1">
        <property type="nucleotide sequence ID" value="XM_008092581.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7B4"/>
    <dbReference type="STRING" id="645133.E3Q7B4"/>
    <dbReference type="GeneID" id="24407937"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02572"/>
    <dbReference type="eggNOG" id="KOG3094">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047877_2_0_1"/>
    <dbReference type="OrthoDB" id="337750at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005793">
        <property type="term" value="C:endoplasmic reticulum-Golgi intermediate compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005578">
        <property type="entry name" value="Yif1_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14083">
        <property type="entry name" value="YIP1 INTERACTING FACTOR HOMOLOG YIF1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14083:SF0">
        <property type="entry name" value="YIP1D-INTERACTING FACTOR 1, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03878">
        <property type="entry name" value="YIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="183"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="250"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="302"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU368073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ26752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="321" mass="35962" checksum="A3C2BD842E911EEB" modified="2011-01-11" version="1">MQRPQTYGQSPPLHHPVPQHVSTVPQLRSPPLPVSQSQSQQGYNSPYQQQGGASGNVFGAYGQFMNDPTAQVAAQFGQSAFRHGQEYMEQNFNRYVNVNALKHYFNVSNSYVINKLFLVLFPWRHKPWSRKQSVGPSGQEGWYLPPRDDINSPDMYIPVMAVVTYILLSTLIAGLRGQFQPELLGYTASTALVIVVAEILGLKLGCYLLGISNDSQLYDLIAYSGYKFVGIIVTVAVAETFNGGKGTGGWIGWSVFLYTFLANSLFLMRSLKYVLLPENSANGVGPMQTGDSRAKRNQRTQFLFFYSYIVQLLFMWILTRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8E3</accession>
    <name>E3Q8E3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Coronin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_02326</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Binds to F-actin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the WD repeat coronin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091175.1">
        <property type="nucleotide sequence ID" value="XM_008092984.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8E3"/>
    <dbReference type="STRING" id="645133.E3Q8E3"/>
    <dbReference type="GeneID" id="24407691"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02326"/>
    <dbReference type="eggNOG" id="KOG0303">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026859_3_1_1"/>
    <dbReference type="OrthoDB" id="1850764at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030139">
        <property type="term" value="C:endocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990819">
        <property type="term" value="C:mating projection actin fusion focus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110085">
        <property type="term" value="C:mitotic actomyosin contractile ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071933">
        <property type="term" value="F:Arp2/3 complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051666">
        <property type="term" value="P:actin cortical patch localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071846">
        <property type="term" value="P:actin filament debranching"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034316">
        <property type="term" value="P:negative regulation of Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000601">
        <property type="term" value="P:positive regulation of Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000197">
        <property type="entry name" value="Coronin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015505">
        <property type="entry name" value="Coronin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015048">
        <property type="entry name" value="DUF1899"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10856">
        <property type="entry name" value="CORONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10856:SF0">
        <property type="entry name" value="CORONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08953">
        <property type="entry name" value="DUF1899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
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        <property type="entry name" value="WD40_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM01166">
        <property type="entry name" value="DUF1899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01167">
        <property type="entry name" value="DUF1900"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8 9" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="DUF1899" evidence="11">
        <location>
            <begin position="4"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="77"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="133"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="175"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="409"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="578"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="411"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="422"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="447"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="464"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="482"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="522"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00062568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU280818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ27155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="612" mass="66661" checksum="B349A716ACF78256" modified="2011-01-11" version="1">MAGRFVRASKYRHVFGKPTRKEFCYDNLRISRNAWDTNLVKANPDYLSVNWEAGGGGAFAVIPLGETGKVPDQIPLFRGHTATVLDTDWNPFNDRVIASGSEDGKVFIWQVPENFTLYTDAEEPADVSPVGKLAGHSRKVGQVQFNPAAENILASASGDFTIKLWDINNGSSTHTLKHNDIVQSLSWNASGSLLVTTSRDKKIRVWDVRAEKPVHEAPGHPGAKNSRAVWMGEHNRFATAGFSRMSERQLALWEPGRNEPIGGFSMLDSISGVIMPFWDEGSNCLYLAGKGDGNIRYYEYENDKFEYLSEYKSAEPQRGIAFVPRRGINVHDNEVMRAYKTVNDTHIEPISFTVPRRAETFQSDIFPPATGLKPAVSAQEWLGGKDGIPAKIDLESVYEGTAPKEVASDYKPPAIASAPAPAAKPAPKPAPAPEPTPVARSPPPSMRDQQVSMSNMASKFKDDEPAEPEDDDDNSSFEEIQRPAQRAAVPAAAAAPAPAPAPAPAPARVEPANIPPPIKAPSPSQIKSPPAQQSPVKASANSPASPTHIESSLDQIRQMLENQTKLISKQNDKISQLSGEVEGLKRKVNAGGSQDQSERIRQLELELEAARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8H6</accession>
    <name>E3Q8H6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Isochorismatase hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_02359</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091208.1">
        <property type="nucleotide sequence ID" value="XM_008093017.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8H6"/>
    <dbReference type="STRING" id="645133.E3Q8H6"/>
    <dbReference type="GeneID" id="24407724"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02359"/>
    <dbReference type="eggNOG" id="ENOG502S0MF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068979_0_0_1"/>
    <dbReference type="OrthoDB" id="167809at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00431">
        <property type="entry name" value="cysteine_hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050272">
        <property type="entry name" value="Isochorismatase-like_hydrls"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43540:SF9">
        <property type="entry name" value="FAMILY HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G08700)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43540">
        <property type="entry name" value="PEROXYUREIDOACRYLATE/UREIDOACRYLATE AMIDOHYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179519" evidence="3">
        <location>
            <begin position="23"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="Isochorismatase-like" evidence="4">
        <location>
            <begin position="99"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ27188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="319" mass="35019" checksum="B194F62D40F3DD95" modified="2011-01-11" version="1">MHLPQLWRPLVLALHAAAPALAQVFDTYATFNALAGNGDSTDAALLGNYYNYWKLLSTNATTNRTTWDLTRSARMATTSPKEIPMSGNRASAIIEPSRSAFVIIDMQNFFLHPKLTPSATLGRAAVGPTVNLINAFRESGVKILWTNWGFDDYDLIISPPVDLDGFSDDHTRATSFCSDMGTIEGDNGETVQVGKKLCRGSWNARPYGDLDDEMVRGVEQGTDFYFNKNRVSGLWGAQTPLGLYLQENSITTLFFGGVNSDQCVWGALLDAYYKGFDVVYVPDCAATISPWYAEQMVRYNADLNGFIANSSDIIAALKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q972</accession>
    <name>E3Q972_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA polymerase II subunit A C-terminal domain phosphatase</fullName>
            <ecNumber evidence="6">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_01746</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">This promotes the activity of RNA polymerase II.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="6"/>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091271.1">
        <property type="nucleotide sequence ID" value="XM_008093080.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q972"/>
    <dbReference type="STRING" id="645133.E3Q972"/>
    <dbReference type="GeneID" id="24407111"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01746"/>
    <dbReference type="eggNOG" id="KOG0323">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007683_0_2_1"/>
    <dbReference type="OrthoDB" id="10249888at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008420">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd17729">
        <property type="entry name" value="BRCT_CTDP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000142">
        <property type="entry name" value="Similar to FCP1-like phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039189">
        <property type="entry name" value="Fcp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011947">
        <property type="entry name" value="FCP1_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02250">
        <property type="entry name" value="FCP1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23081">
        <property type="entry name" value="RNA POLYMERASE II CTD PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23081:SF36">
        <property type="entry name" value="RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="9">
        <location>
            <begin position="158"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="8">
        <location>
            <begin position="526"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="337"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="486"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="628"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="357"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="368"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="637"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="669"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="711"/>
            <end position="732"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ27251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="860" mass="95020" checksum="48D91F22716A4210" modified="2011-01-11" version="1">MGKLLPLGARLRYPITVTKLLKSPGDTIKKQESILEYSYKSMREYGDPIAGETWQEEVTTIAGWDSPAEGTLKEWRLKEGMTLTRDAPCMLVEEACSHEIQFQGLCAICGKDMTEVNWASDQRDTQRATINMTHDQTGLMVSGDLAARAEHETQKRLLRQRKLSLVVDLDQTIIHACIEPTVGEWMEDPSNPNYQAVKDVKKFQLNDEGPRGMVTSGCWYYIKMRPGLAEFLEKVAELYELHVYTMGTRAYALNIAKIVDPHQKLFGNRVISRDENGSMISKSLQRLFPVNTNMVVIIDDRADVWPNNRPNLIKVVPYDFFKGIGDINSSFLPKRQDILPAPTTEPGATPAPPEAPKPVDARPDDTRQQQQQQQQQQQQPNGKVSALDELVKMSSGDDKVLQAAQTGEQEKLLEQQIMERPLLHMQEELDKQDEQKEKATLDTEDGPHIMTVQHRSQVLRDDDAELVYLQQHLAELHRKFYEEYDEKRASMPAQPAPRNKKTGGGGDDTNIDLAAVPDVGFVLDTMKASTLQGTTIVLSGLVPLGVDVLQSEIGIQAMSFGAQLSTKVSKKVTHLVMSTSRPRTQKVRQAAKIPSIKIVSQNWLTDCLSQWQHVDETPYLVAVHPADRRRHAASETTDADTVSDVDDDDDLSRPHLTIIDETGEHRILEEDDDDASDEDDGGQDGDEDNLMPDFEDGQTSPIDDLKTFDWEGVDDEMKEFLGSDDDDSSDADTESRSGDTEVGDEPPSSQESANGVTGGGGGGTKRKAMDDDTASDEGGSALSKKQRVAKSRGASKLSSVRTPNAEDNESSSLPTPQVTGDEEDVSLVPDSAAVDGGDNDFDEDDLEADLEAELAAAGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9B5</accession>
    <name>E3Q9B5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_01789</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091314.1">
        <property type="nucleotide sequence ID" value="XM_008093123.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9B5"/>
    <dbReference type="GeneID" id="24407154"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01789"/>
    <dbReference type="HOGENOM" id="CLU_2170876_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ27294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="110" mass="11635" checksum="BA6B83FABD012F50" modified="2011-01-11" version="1">MPCPFRALANPHARLKGVTGVDDILESGAVRLEAAGIAAAQRLQQTMCDYDPGAELLGNRSLEAGTLAQGLVRVGGGGGEVVITAEPVQERRRRGRLSVVHEELPAREPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9T6</accession>
    <name>E3Q9T6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_02768</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091644.1">
        <property type="nucleotide sequence ID" value="XM_008093453.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9T6"/>
    <dbReference type="GeneID" id="24408133"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02768"/>
    <dbReference type="eggNOG" id="ENOG502T4AS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032743_0_0_1"/>
    <dbReference type="OrthoDB" id="5224238at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ27624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="469" mass="53489" checksum="F7F8ED85F999CD5C" modified="2011-01-11" version="1">MAANALPVELIELIFAHVSSTGDTKSLRLSCRAFADVGFLYLFTTSFTHLSWRDDVMRLENWSRHDRLRRHLRSWTVNLARLNEHPGRHASFFQYWLMDPEDRESLVLRHGWAEFYDAEARRKAMACLAEEEEEDVRRLVNAAARLKALEQARILFNECPYEGVILRRAFADPSVRWFEPCEASTMLGILAMVLRRFGCLKSFEVDRLPMKMAPSVKTETAWCEFARSVGERLEEVKLGLDYSGSAGEETAGETMGDVSGSWTQLVEVLLASCRRVKSLEVKQHFYRPLGDRSRKTGRLNQVLLRCTTWRLTDLKLEGFATTQEELSGFLRGQLATLKRLRLGGRGVASVRDKSRGGIWLEMGTWFGFFTGLRGRLRADKAGCVLEKIHLEGDFRQVDRVEVDGEDRGLVENYDFYPITDDNWALLETPAWVRAGFSTNYLDGSAFARYALGDEDMSYPGFTEGLLGEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAE5</accession>
    <name>E3QAE5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glutathione-dependent formaldehyde-activating enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_02977</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091853.1">
        <property type="nucleotide sequence ID" value="XM_008093662.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAE5"/>
    <dbReference type="GeneID" id="24408342"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02977"/>
    <dbReference type="eggNOG" id="ENOG502SRJN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055491_1_1_1"/>
    <dbReference type="OrthoDB" id="5290969at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1590.10">
        <property type="entry name" value="glutathione-dependent formaldehyde- activating enzyme (gfa)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337:SF3">
        <property type="entry name" value="CENP-V_GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337">
        <property type="entry name" value="GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="6">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="122"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ27833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="168" mass="18237" checksum="B975BEC1562374DF" modified="2011-01-11" version="1">MDARCQCGAVRFKTPLPKPLRLYVCHCDECKRQTGSAFGTSAIFPKFQLPKAELMGVYARPTASGATLYCYFCRNCGTRLIHATPDKNVVSVKGGCIDGLDWKTAVHIWTKSAMVPIPEGAESHDEEAEYTDYGPTQEALDQPTDLRGSGGTKPDGRCELSGGAVVHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAP7</accession>
    <name>E3QAP7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Urease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_03079</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the UreF family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ27935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091955.1">
        <property type="nucleotide sequence ID" value="XM_008093764.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAP7"/>
    <dbReference type="STRING" id="645133.E3QAP7"/>
    <dbReference type="GeneID" id="24408444"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03079"/>
    <dbReference type="eggNOG" id="ENOG502REVQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049215_0_0_1"/>
    <dbReference type="OrthoDB" id="2550922at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4190.10">
        <property type="entry name" value="Urease accessory protein UreF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002639">
        <property type="entry name" value="UreF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038277">
        <property type="entry name" value="UreF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33620">
        <property type="entry name" value="UREASE ACCESSORY PROTEIN F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33620:SF1">
        <property type="entry name" value="UREASE ACCESSORY PROTEIN F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01730">
        <property type="entry name" value="UreF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0996">Nickel insertion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="10"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00046339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ27935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="301" mass="32478" checksum="DBEE0E1842DF836E" modified="2011-01-11" version="1">MDSNARDGSVDDAEKEVLELEARLEAARGKLKSLKGEALESCESLSFRGLPKPSLSLTLSNHYLLLLSDSALPLGSFAFSSGLESYLAHTRGRSSFNVFLPESISAYASTTLPFVVAAHRDPNALAELDDHLDAAIICTVGRRASIAQGRALLSIWERSFATSLPAHVVATLQPYVAMLKAATSSRVSSTADDSAEPPLVFAHLAPLFGAVSNLVGLSLQQTAYIFMMGHVKALISAAVRASMFGPYQAQKVLASTQVQQLITAAIDREWDTPIERAGQTMPVMDLWIGRHEVLYSRIFNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QC07</accession>
    <name>E3QC07_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ureidoglycolate hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_03386</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092262.1">
        <property type="nucleotide sequence ID" value="XM_008094071.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QC07"/>
    <dbReference type="STRING" id="645133.E3QC07"/>
    <dbReference type="GeneID" id="24408751"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03386"/>
    <dbReference type="eggNOG" id="ENOG502S7CF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051290_0_0_1"/>
    <dbReference type="OrthoDB" id="2967263at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009097">
        <property type="entry name" value="Cyclic_Pdiesterase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55144">
        <property type="entry name" value="LigT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ28242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="323" mass="36365" checksum="CB142432C74C79E5" modified="2011-01-11" version="1">MGTQLVSADAMNKLEDLSGITVLPGQNPYNALIKACNDSSAEIQALYHTHRVKRNEQQKQKFMAPSYEGLIIDRILLRLENPEIEPGFKDPRNCFVFWARPPEHILRLAAHVQALLKKAAPSVWLMPQHRMHLTTLEVTHSKTPEEIIALTDTMRSVIPYITDYTYSHRARLVKPMVSYDLSAFALSFLTAAGEPPLGPPPATTAAQKAVVEGDGYTYHHLRRDVFDLARSTGVSIESRYQVPSAHITLGRYLTEEDHATPEARARWVEAIDTVNAWLEGEVWDLKDGEWVGEWVVGQERGLEARNGRLWYGGGRTIRLGEGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCR6</accession>
    <name>E3QCR6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ribosomal protein L23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_03798</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL23 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092674.1">
        <property type="nucleotide sequence ID" value="XM_008094483.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCR6"/>
    <dbReference type="STRING" id="645133.E3QCR6"/>
    <dbReference type="GeneID" id="24409163"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03798"/>
    <dbReference type="eggNOG" id="KOG1751">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037562_0_1_1"/>
    <dbReference type="OrthoDB" id="1267328at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000035">
        <property type="entry name" value="60S ribosomal protein L23a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01369_A">
        <property type="entry name" value="Ribosomal_uL23_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013025">
        <property type="entry name" value="Ribosomal_uL23-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_uL23/eL15/eS24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005633">
        <property type="entry name" value="Ribosomal_uL23_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF011118">
        <property type="entry name" value="PRK14548.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11620">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L23A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00276">
        <property type="entry name" value="Ribosomal_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03939">
        <property type="entry name" value="Ribosomal_L23eN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="Ribosomal proteins S24e, L23 and L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL23 N-terminal" evidence="7">
        <location>
            <begin position="18"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="9"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ28654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="157" mass="17314" checksum="6C3D28AEE1F0EF4C" modified="2011-01-11" version="1">MAPKDSKKGGASKAPKGTKQANNAAKAALKGAHGHYKNKVRYTTSFHRPKTLVVSRAPKYPRKSVPHEPRLDEHKVIVHPLNTESAMKKIEENNTLVFIVDVKSNKAQIKQALKKLYDIDTVKINTLIRPDGSKKAYARLTPDVDALDIAATKLALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCS8</accession>
    <name>E3QCS8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Vacuolar protein sorting-associated protein 45</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_03810</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the STXBP/unc-18/SEC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092686.1">
        <property type="nucleotide sequence ID" value="XM_008094495.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCS8"/>
    <dbReference type="STRING" id="645133.E3QCS8"/>
    <dbReference type="GeneID" id="24409175"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03810"/>
    <dbReference type="eggNOG" id="KOG1299">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013933_3_1_1"/>
    <dbReference type="OrthoDB" id="10266265at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.830.10:FF:000002">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.830.10">
        <property type="entry name" value="Syntaxin Binding Protein 1, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043154">
        <property type="entry name" value="Sec-1-like_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043127">
        <property type="entry name" value="Sec-1-like_dom3a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001619">
        <property type="entry name" value="Sec1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027482">
        <property type="entry name" value="Sec1-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036045">
        <property type="entry name" value="Sec1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11679">
        <property type="entry name" value="VESICLE PROTEIN SORTING-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00995">
        <property type="entry name" value="Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005715">
        <property type="entry name" value="VPS45_Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56815">
        <property type="entry name" value="Sec1/munc18-like (SM) proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00073001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ28666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="582" mass="65144" checksum="FA592924D0C6E857" modified="2011-01-11" version="1">MDVAQAVAGYVSRMISSADSSSQSAKMKVLLLDRETVPIVSTAITQSALLNHEVYLIDRIDNVNREKMRHLRCLCLVRPSPESIQLLIDELREPKYGEYHLYFTNVVKKSSLERLAEADDHEVVKLVQEHFADFIVINPDLFSLGLGLPHQRVWASSPDTWNSDALQRSADGLIAVLLALKKKPLIRYAKNSPLTKKLATEVRYRITQEEQLFDFRKVDTPPILLIIDRREDPATPLLTQWTYQAMVHHLLGITNGRVDLSDVPDIRPELKEIVLSQDQDPFFKKNMYLNFGDLGGNIKDYVEQYQSKTQNSANIESISDMKRFIEEYPEFRKLSGNVSKHVTLVSELSRRVGAENLLEVSELEQSLACNDNHATDVKNIQKLIQSPRVTSDSKVGLVALYALRYERNPSNALPMLVDLLVAAGGVSVRRADLVSKLVTYRSTLQQSQTQTGITDIFEGAGIFGGAGNRFKGLKGVENVYTQHSPMLESTLQNLIRGRLKEQQYPFVEGGGTTRDKPQDIIVFIVGGATYEEAKTVATINASTPGVRLVLGGTTIHNSATFLEEVEDAVSLWPETQKPAARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDX6</accession>
    <name>E3QDX6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pyridoxal-dependent decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_04208</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the group II decarboxylase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093084.1">
        <property type="nucleotide sequence ID" value="XM_008094893.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDX6"/>
    <dbReference type="STRING" id="645133.E3QDX6"/>
    <dbReference type="GeneID" id="24409573"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04208"/>
    <dbReference type="eggNOG" id="KOG0628">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011856_6_2_1"/>
    <dbReference type="OrthoDB" id="2161780at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010977">
        <property type="entry name" value="Aromatic_deC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021115">
        <property type="entry name" value="Pyridoxal-P_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11999:SF165">
        <property type="entry name" value="DECARBOXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G04980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11999">
        <property type="entry name" value="GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00392">
        <property type="entry name" value="DDC_GAD_HDC_YDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 5 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="5">
        <location>
            <position position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ29064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="493" mass="52635" checksum="72B1874B69E5673F" modified="2011-01-11" version="1">MATPDFHARLRAALSPEGDDAPTLPPATALANASASLPRPGEEGYLFPLGTEATLSHIVDEVVPGLNGQARSGRYYGFVTGGSLPVAEAADNIVSALDQNVQVHLPSQTVATELESVALRMLADVLGLEDGKDGESEVWKGRTFTTGATASNILGLACGREAVVEKRGGKVGEEGLLGACLAAGVKEIQVLTSMGHSSLSKAASVVGLGRAGVKELSAKADEPWRLDLDAVEKHLGRQGVASIIAVSAGEVNTGRFATGGFDEMRRLRELADRFGAWIHVDGAFGIFARALEPTPEFERIRDMASGLELADSITVDGHKLLNVPYDCGMFFTRSLSTLTSVFINPNAAYLSSGPSLIPSPLNIGLENSRRFRALPAYAVMRSEGRAGLAAILGRMVRLARRLAQWIRESEAYELLPEGAWGLEETHMVVLFRARDAEANEELVGRINATREMYVSGTSWKGRKAVRVAVGSWKVDVERDFSVVTRILGDVAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QE56</accession>
    <name>E3QE56_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_04288</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093164.1">
        <property type="nucleotide sequence ID" value="XM_008094973.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QE56"/>
    <dbReference type="STRING" id="645133.E3QE56"/>
    <dbReference type="GeneID" id="24409653"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04288"/>
    <dbReference type="eggNOG" id="KOG0601">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009707_0_0_1"/>
    <dbReference type="OrthoDB" id="5337378at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004713">
        <property type="term" value="F:protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110031">
        <property type="term" value="P:negative regulation of G2/MI transition of meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000611">
        <property type="entry name" value="Protein kinase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050339">
        <property type="entry name" value="CC_SR_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042:SF196">
        <property type="entry name" value="MITOSIS INHIBITOR PROTEIN KINASE SWE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="724"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="29"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="268"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="497"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="587"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="37"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="84"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="165"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="269"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="292"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="390"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="418"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="608"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="646"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="673"/>
            <end position="705"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ29144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1112" mass="120640" checksum="516E069F78C2AD0A" modified="2011-01-11" version="1">MSFSNSSGGTLTVPSPTHVHHADVLASSVRSLRRSLSRSPSKFSLARTSSPSSESSHSGSHTPVQQQSPCRRYTPTPTPPSSSHDNTTAFGESFQSHTPAGLPHSMTSTTPFSSPPSLATPFRPNVRLSLRSAKTSKATGSPSRPATRLRTSPKSPLKRALSATTESGVNSTPSSSSSSEASGQENNQSSAQQSPHSRSSAQKSRHSLHLDVSGHAQQTNIFKHLESNGDSQGAPGSGALKRSDAIMNLDQASLGSPVAKRRSLHGISNFGQNTTDFNIFDNTSSTTSKTNFDIHDEANREREYELFGSSPAAREPFSSPTPPPQIPRRTGSLRRSTLQQRQHDRSSWGRKSGANHLAQMAGEFSSPNLKNRPRLSMDQFLPPQLPRDSPFTSNGSLPNPSAHPIDRPFHQPHPLSKTLVTSTSGNNLEEQNNSMPPPYVFEKPRAPLSFAKSMPYGSSRPSFMQEEGENVTPFKAAKPWAGAFMSTGLVSKVNRNPEEDNKLTMPDTPCKKPTNGFATFPPPPGSAIKKSNRYSFGGMPSTPFNAPGAPSRSTFGNPGKGLGIFQRLGSRHARRGSVLSLDDDKKFSLDTNFNVGPGAETDAPPTPTKQGLTPSLSNLSERSIESPSAKRSLPPPMSAVRPMISRESTASPVEQRSPRTPSTHVILPDASCLSISNPAESQSTTTPVTPSGRDSFQSTTTQLMTPVNAGRGNADVDDSLYSRFDKVEMVGKGEFSSVYRVVKAGYSRASFLSVFSGTPTKNPRESPEPDRIYAVKKARRQFTGPKDRLSKLREVQALQALTHADHVVHYVDSWEYNQYLYIQTEYCDEGTLDKFLSNVGRKGRLDDFRIWKVIHDIGLGLQSIHEAGFIHLDLKPANILITFEGILKIGDFGLATEWPAAKGVDAEGDREYIGPEILRGDFNKPADIFSLGLITIEMAANVVLPDNGPTWVALRSGDLSEVPSLTFSATTTINAHRDAAGVPTVQSLDDPLLGQTSAPDISLHSGAAPTRVSVIMDDESPFITRKRTELRSPPDFMSDPFHPSSLDQIVRWMISPEPSERPTIQQLLSTPSMVWVAQRRRSAATVFEGVWGPSESTALPTLVDEDIEMMDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QE93</accession>
    <name>E3QE93_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_04325</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093201.1">
        <property type="nucleotide sequence ID" value="XM_008095010.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QE93"/>
    <dbReference type="STRING" id="645133.E3QE93"/>
    <dbReference type="GeneID" id="24409690"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04325"/>
    <dbReference type="eggNOG" id="ENOG502RZT7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044590_1_0_1"/>
    <dbReference type="OrthoDB" id="2135488at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052350">
        <property type="entry name" value="Metallo-dep_Lactonases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43569">
        <property type="entry name" value="AMIDOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43569:SF2">
        <property type="entry name" value="AMIDOHYDROLASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="2">
        <location>
            <begin position="118"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ29181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="346" mass="38336" checksum="809B129CA74BFBB0" modified="2011-01-11" version="1">MAADYPIVDSHIHLYPESELETLAWATPGDPLVTQRSVSDYVAATGSPANLKGFIFLETDRKHDLEAGARDGSGWEFPLMEVAWLRRIAEGKPRDGEGHTPDQASLCLGIVPWAPLPSGAAAMERYLDRVKEVAGEAVWPKIRGFRYLLQSKPHGTGLTDDFIAGLKLLGKRGFVFDLGVDQHRRGNKQLDDTLEIISRAHEGVPEEEKVTFVINHLCKPDLGIINTTDPSFVHWRTAVYALSKCSNTYIKLSGGFSEMPDSLKSQDPNAIFEAIFPWLGVVLATFGTRRTMFGSDWPVCTVGVEEAWRKWKLLVERTCYMATLEPEDQAALFGGTALKAYGIKDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEA0</accession>
    <name>E3QEA0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_04332</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093208.1">
        <property type="nucleotide sequence ID" value="XM_008095017.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEA0"/>
    <dbReference type="STRING" id="645133.E3QEA0"/>
    <dbReference type="GeneID" id="24409697"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04332"/>
    <dbReference type="eggNOG" id="ENOG502RAKP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_921356_0_0_1"/>
    <dbReference type="OrthoDB" id="4834836at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179658" evidence="2">
        <location>
            <begin position="24"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="135"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ29188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="312" mass="32783" checksum="D825AF3DFEF0C578" modified="2011-01-11" version="1">MHYINKILHFCVALHVVFQGASGAILRGRTSDADSVQVPPSNLDSFTSAAEDLDNQLDSFLRKWGGGHRKPDIVEIANMAKRQAGGIQIASEDLQDLLRLIQSIERQLSAIIASGGSSASGTVVSSPVSNTVSNTVSNTVSNTVSNTGPVSSPPAPSNEQLTDTGTNPAVTSVSAPTPSPFLTTSGAGNSESLTTAYATSVMTTTRCKTTVTRTYTTYVYEDGPSAAPRAVRAVVEGDDEIGGPDPSPTQDLEQDDDWEPWVEFDGTTGDEDGSDVGFTTRDTWTSLGVSRRAPGGVSSHAEALFARDEESP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEA2</accession>
    <name>E3QEA2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">SPRY domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_04334</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the proteasome-dependent degradation of fructose-1,6-bisphosphatase.</text>
    </comment>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093210.1">
        <property type="nucleotide sequence ID" value="XM_008095019.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEA2"/>
    <dbReference type="STRING" id="645133.E3QEA2"/>
    <dbReference type="GeneID" id="24409699"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04334"/>
    <dbReference type="eggNOG" id="KOG1477">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009129_2_0_1"/>
    <dbReference type="OrthoDB" id="25503at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12909">
        <property type="entry name" value="SPRY_RanBP9_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001870">
        <property type="entry name" value="B30.2/SPRY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013144">
        <property type="entry name" value="CRA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024964">
        <property type="entry name" value="CTLH/CRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006595">
        <property type="entry name" value="CTLH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003877">
        <property type="entry name" value="SPRY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035782">
        <property type="entry name" value="SPRY_RanBP9/10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050618">
        <property type="entry name" value="Ubq-SigPath_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12864">
        <property type="entry name" value="RAN BINDING PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10607">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00622">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00757">
        <property type="entry name" value="CRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00668">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00667">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00449">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50188">
        <property type="entry name" value="B302_SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50897">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B30.2/SPRY" evidence="3">
        <location>
            <begin position="194"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="CTLH" evidence="4">
        <location>
            <begin position="473"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ29190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="696" mass="75881" checksum="4B87B89E07248516" modified="2011-01-11" version="1">MTNPFHGSAHYTDPNSPSGTSGLPPRRFSYASVVSGAPPNYNPPYLSHPGRTSVISHILNSSDDITFEPASAYYNPSRSDDMDTDRNGAGLSGASARPLSGFQLPSFSRAFDMFMANPLGEPAGSSSASGSGFFVPSYLAGSAHVQRLEEAHWAKVRAQKESQAAQAQAGANLSTSASSVSLHSKPGAHRGVNYDVIEKPPAFEEDETFAPLPTRWNSSDKYGALDIMSDGLEVRYIGPRGQTERDHEAFCIRADNPMPPQCGIYYFEVQVLSGKRDDMTIGIGFSGKNVGLSRPPGWETDSWGYHSDDGHCYAGQSGGKTYGPSFTASDIIGCGVNFRTGNAFFTKNGHLLGTAFREVGKSGSLYPTVGLKKSGEHVRVNFGQTPFVFDIDGMMTTERERIQREISRTSSASLAPAMNETGLVQALVLQFLQHDGYVETARAFAEEINAEKKALCLDPNAPIEGINVKDDEHANKRQRIRRAVLEGDIDRALKHTNAFYPQVLKDNEQVYFRLRCRKFIEMVRTAAEMRVASEAKKSNGHGGDVGAQAMDLDANGTENGAWDQTDTEDSAETSLDINELEMATLQYGQELHAEFKDDPRREVTKHLADIYALLAYANPLREKDVAHLLDRKGRLAVAEELNSAILLSLGKSSRAALEKIYAQTSVLLDDLRENGGPGAFVSLQDVIEDIPKSQPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEK1</accession>
    <name>E3QEK1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Caspase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_04451</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C14B family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093327.1">
        <property type="nucleotide sequence ID" value="XM_008095136.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEK1"/>
    <dbReference type="STRING" id="645133.E3QEK1"/>
    <dbReference type="MEROPS" id="C14.035"/>
    <dbReference type="GeneID" id="24409816"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04451"/>
    <dbReference type="eggNOG" id="KOG1546">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029389_0_2_1"/>
    <dbReference type="OrthoDB" id="3223806at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006915">
        <property type="term" value="P:apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050452">
        <property type="entry name" value="Metacaspase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011600">
        <property type="entry name" value="Pept_C14_caspase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104:SF30">
        <property type="entry name" value="METACASPASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104">
        <property type="entry name" value="METACASPASE-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00656">
        <property type="entry name" value="Peptidase_C14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="Caspase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0865">Zymogen</keyword>
    <feature type="domain" description="Peptidase C14 caspase" evidence="6">
        <location>
            <begin position="168"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="97"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ29307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="462" mass="49549" checksum="15D0601B5BC65EA6" modified="2011-01-11" version="1">MSGYPGQYGYGAGGHDGGYGGSGGYQQGGYGSQHQGGGGGYGGYQPPPGPPPSQQHGGYGGGYDRPPPGPPPGQGGYGYNQPPPNPYPDQSYVGRYAPPPYPPPPGLDVYGYPVNSGHQGRPNMPTVNSNDWAHGNRNAPPPPPSGAQQFGHGAPEGYSFQYSTCQGKRKALLIGINYFGQDGELRGCINDVKNLSAFLVERYGYKREDMVILTDDQQQPMGQPTKNNILRAMHWLVQGAQPNDSLFFHYSGHGGQTEDIDGDEDDGYDEVIYPVDFKEAGHIVDDEMHHIMVKPLQPGVRLTAIFDSCHSGSALDLPYIYSTKGVLKEPNLAKEAGQGLLNAFTAYASGDLGAVASSIFSFGKRAMAGDDAYEKTKETRTSPADVIMWSGSKDSQTSADATIANQATGAMSYAFITALKAKPQQSYVELLNSIRDVLQEKYTQLPQLSSSHPIDTDILYVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFA6</accession>
    <name>E3QFA6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">S1/P1 Nuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_04688</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the nuclease type I family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093564.1">
        <property type="nucleotide sequence ID" value="XM_008095373.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFA6"/>
    <dbReference type="STRING" id="645133.E3QFA6"/>
    <dbReference type="GeneID" id="24410053"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04688"/>
    <dbReference type="eggNOG" id="ENOG502QRXU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044365_0_0_1"/>
    <dbReference type="OrthoDB" id="441446at2759"/>
    <dbReference type="PHI-base" id="PHI:10751"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11010">
        <property type="entry name" value="S1-P1_nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.575.10">
        <property type="entry name" value="P1 Nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008947">
        <property type="entry name" value="PLipase_C/P1_nuclease_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003154">
        <property type="entry name" value="S1/P1nuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33146">
        <property type="entry name" value="ENDONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33146:SF26">
        <property type="entry name" value="ENDONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02265">
        <property type="entry name" value="S1-P1_nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48537">
        <property type="entry name" value="Phospholipase C/P1 nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180392" evidence="8">
        <location>
            <begin position="20"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ29544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="304" mass="33722" checksum="62FBED0E5E932AE7" modified="2011-01-11" version="1">MKFSSIVALLGAPLPGVLAWGSLGHIATAYLASHFVANATEAFFQDLLRNDTEHYLAGVATWADTIRYTRWGHFTGPFHFIDAHDSPPGYCDVDLERDCKAQGCVVTALANYTARSLDPTLSGWERNQAARFVVHFIGDMHQPLHNEDVARGGNGIHVKWHGTDFNLHHVWDSSIAEKLIGGSRRRPYDNAKRWADHLAEEIETGKFAEQKAEWLKSLDFNNVNSTGLQWAKEGNAFVCTHVFPKGPRAIVGQELGGEYFEKAAPVIELQVARAGVRLATWLDLIAAAYENQARKATVVAMEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFF3</accession>
    <name>E3QFF3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_04735</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093611.1">
        <property type="nucleotide sequence ID" value="XM_008095420.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFF3"/>
    <dbReference type="STRING" id="645133.E3QFF3"/>
    <dbReference type="GeneID" id="24410100"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04735"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_13_0_1"/>
    <dbReference type="OrthoDB" id="4500315at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000396">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1720.10:FF:000009">
        <property type="entry name" value="MFS multidrug transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF4">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="114"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="210"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="240"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="269"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="451"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="495"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="540"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="567"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="612"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="634"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="115"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="65"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="304"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="354"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="400"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ29591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="673" mass="74089" checksum="26B5FC6A2323D8D3" modified="2011-01-11" version="1">MAGVPTWKSRFGGLFGNKNGKDDATEEDTHSNIPKWSLGVLNDPQTLEVPGSVFLLGSHNAPMGVSNTPARTAHSSMPDPTREAKTTKDGTVLNPQPEESANDPLNWPEWRRDCALLALGFYCMVGGGMTPLLAAGFTNVAQDYHIDTETVSLTTGLFMMGLGLGSVIFSPTAILYGKRPVYLFSAVIFIVSSVWAALSPNFTSLILARIFQGIAVSPVECLPSATIAEIFFLHERAFRIGIYTLLLLGGKNLVPLVSAVVIQALGWRWVFWVVTMVVAFAGVLLYFFVPETFWDRIPAPTRDAAQSRRSSMQKRDLAAGMEPTSASPTLEPPHSPSHQQTDEAIRFALATNQDGQGAKDPEKEPGSAFDSSNPTPARRTSDTSGDYYAKETGIEAQKVPTRSSGESSPSMSLAYTETLRNQPAKSFTEQLKPWNGRLNQDRWFKVMLRPFVLFAYPAVFWSAVVYSLSVGWLIVVSESVALIYRNRKSYNFDALQTGLVYLSPFIGGVLGTAVAGKVSDIIVKSMARRNGGLYEPEFRLVMAAPVAVTTVVGLMGFGWSAQERDHWIVPTVFFGIISFGCTLGSTTAITFCVDSYRQYAGEALVTLNFSKNIFHGLVFSLFVTHWLADDGPKMVFIWLGIIQLIFLFLTIPMYLYGKRARMWTTRKNLMEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFR9</accession>
    <name>E3QFR9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_04898</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C19 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093774.1">
        <property type="nucleotide sequence ID" value="XM_008095583.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFR9"/>
    <dbReference type="STRING" id="645133.E3QFR9"/>
    <dbReference type="GeneID" id="24410263"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04898"/>
    <dbReference type="eggNOG" id="KOG1867">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008279_6_0_1"/>
    <dbReference type="OrthoDB" id="2020758at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02662">
        <property type="entry name" value="Peptidase_C19F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF888">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="10">
        <location>
            <begin position="152"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="543"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="661"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="543"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ29754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="685" mass="75275" checksum="B3B557A05FD1FACC" modified="2011-01-11" version="1">MNSPGSFKDTYGPDYHRQIHDEAFWKRLTEPSVVVSLFALVATAVYSIFGASALPKPLLSRAGRTLWDVLVWLIPFGALTVLEGWLHPPLFPRPMLQNRAKTHAVKSELLKNILGMNMQGGIMGTVSQAGIRGLSSVSGAVMGLKGSSDYPPGLGNLDNSCYQNSILQGLASLKPFPKYLADPVQDPEIDRRKVEAVDTLRSLIADLNSTRNYGKTLWTPGSLKNMSTWQQQDAQEYFSKLLDEVDREIAKAAKATQKLAGFESECVNDDTAASQHSDDSGYQSLSTVSKIGSAKVLRNPLEGLIAQRVACVDCGHSDGLSMIPFNCLTLSLNPGGNDHDLYELLDIYAHIEPIEGVECGKCTLLKAKRLLTTLVERAEASYMDKEKLKEPKLRLAAVNEALDEDDFEDKTLTEKCKFPSQFKVSSTKTKQAVIARPPQSLAVHMNRSVFDENTGMMYKNSSGIRFPLTLDLGPWCLGSAISSRESEEEQWLLDPRSSMIAGDKRKSYITGPIYELRAVVAHYGRHENGHYVCYRKFPRNSPPEEAHEASVKSEASDDNSETDWWRLSDETVRKVDEEEVLDQGNVFMLFYDCVDPAIISLSEVAAADAGVEAITGSADAAAGAEDDETPKVGESMFTCTVKEVSEDDDEESAHCVSVVNEGKAIPPPGDKDTRTSERGPQMITV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHA7</accession>
    <name>E3QHA7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05413</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697348">
        <property type="protein sequence ID" value="EFQ30269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094289.1">
        <property type="nucleotide sequence ID" value="XM_008096098.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHA7"/>
    <dbReference type="STRING" id="645133.E3QHA7"/>
    <dbReference type="GeneID" id="24410778"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05413"/>
    <dbReference type="eggNOG" id="ENOG502T5X1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1844943_0_0_1"/>
    <dbReference type="OrthoDB" id="25921at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="66"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="141" mass="15541" checksum="557A732C3D15FF45" modified="2011-01-11" version="1">MTRNPDPTLIHSHGSDVSACIDLIERGTSRMKEEGLLKYGDLLRAARIKVYGPTSYEPPSVQTHMTDTPSAPPASSSDAVGIFASESLQNPVLFQGEGLETYMSQVTGYFDNTHIGLDEGLTAWFDTFMDELQPGQNREMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHB6</accession>
    <name>E3QHB6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_05422</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697348">
        <property type="protein sequence ID" value="EFQ30278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094298.1">
        <property type="nucleotide sequence ID" value="XM_008096107.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHB6"/>
    <dbReference type="STRING" id="645133.E3QHB6"/>
    <dbReference type="GeneID" id="24410787"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05422"/>
    <dbReference type="eggNOG" id="ENOG502QRAF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038067_0_0_1"/>
    <dbReference type="OrthoDB" id="2264563at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046868">
        <property type="entry name" value="BAR_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046869">
        <property type="entry name" value="SLM1/RGC1-like_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31941">
        <property type="entry name" value="CYTOSKELETAL SIGNALING PROTEIN SLM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31941:SF1">
        <property type="entry name" value="CYTOSKELETAL SIGNALING PROTEIN SLM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20400">
        <property type="entry name" value="BAR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20399">
        <property type="entry name" value="PH_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="300"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="411"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="473"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ30278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="496" mass="53433" checksum="9ED149C45D274AE5" modified="2011-01-11" version="1">MADTKTLPQRSGTIMTNTSSDEAVPEVDPTSTAGLLAERLQAWKHAVGYLEDYMEVVEKIHRAHAKEYEKALKTISHPLKEGHHFDQSLGGVAGYFENMRSNTQAIINTNLETEKSIKGSVLPVLERLHKEIKHKGKELAHGASKGAKEVEKARNTTQKHIELLGQQTAAFESAGGKMHGTDDPYVVHRGVLHRLHKQVLEENNNRNDLIAIQNNFEAFEAHVIGVIQQAMEAFIQLTGSQAEKTRALYSDMLGAIQRVPADLEWKGFVGRSGDRLVNANDPPRSVESVTFPNMDHSAVKPLIEGSLERKSRNKLSWGYSTGYYVVTPAKFLHEFKDSDNARADPKPELSIYLPEAIIGAPNGNKFNVKGKDKSKSISSKLTGSSELAFQAHTPADAQKWFDVIKNVAGATGPAEPNSAPTSTPVSPVVGSDEKMPSIAPAATTQSGHSVQEAGVTGADPTASPELLSPVDEPSSSAAAAPAATPAATAPVGEKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHK8</accession>
    <name>E3QHK8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_05490</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
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        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697349">
        <property type="protein sequence ID" value="EFQ30346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094366.1">
        <property type="nucleotide sequence ID" value="XM_008096175.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHK8"/>
    <dbReference type="STRING" id="645133.E3QHK8"/>
    <dbReference type="GeneID" id="24410855"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05490"/>
    <dbReference type="eggNOG" id="KOG4177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_821390_0_0_1"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF9">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13857">
        <property type="entry name" value="Ank_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="57"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="90"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="123"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ30346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="338" mass="37401" checksum="2EAF333345C144FE" modified="2011-01-11" version="1">MAWLLDNSIAVQVAIDKNCCKVLAVLLSYVSELGTVGGRNLVRELVNNVPTRPGRYSDHSPLHDAVDESNVDIARLLLQYGANVNRQNQARRTPLHIAVEADDLEIVKFLTDHGASIHTRDGHGRTPVEVAVCHASPGMVEFFLEKGASIGRILKSDSNLMCASVNMAISLQKAGINLNQVGGFGVPLWTPMLFKIQLATYILNSDQCVFLHTFERGRVLWKLLWYFYDNDDVNSMHKQLRLMYRRLGHDFMRQISETETDDRHGAFNILCFSAHYGLVEEVKVLLEAGCGIEFEGSAAGTALMAAASLGRIEIVKLCTGLVIDREVYGTDQDRGAIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIH0</accession>
    <name>E3QIH0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA mismatch repair protein MutL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_05724</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA mismatch repair MutL/HexB family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094600.1">
        <property type="nucleotide sequence ID" value="XM_008096409.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIH0"/>
    <dbReference type="STRING" id="645133.E3QIH0"/>
    <dbReference type="GeneID" id="24411089"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05724"/>
    <dbReference type="eggNOG" id="KOG1979">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004131_2_0_1"/>
    <dbReference type="OrthoDB" id="10263226at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032389">
        <property type="term" value="C:MutLalpha complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061982">
        <property type="term" value="P:meiosis I cell cycle process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16926">
        <property type="entry name" value="HATPase_MutL-MLH-PMS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03483">
        <property type="entry name" value="MutL_Trans_MLH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000014">
        <property type="entry name" value="DNA mismatch repair protein Mlh1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000033">
        <property type="entry name" value="DNA mismatch repair protein Mlh1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014762">
        <property type="entry name" value="DNA_mismatch_repair_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013507">
        <property type="entry name" value="DNA_mismatch_S5_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032189">
        <property type="entry name" value="Mlh1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002099">
        <property type="entry name" value="MutL/Mlh/PMS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00585">
        <property type="entry name" value="mutl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073:SF12">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01119">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16413">
        <property type="entry name" value="Mlh1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01340">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00058">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair protein S5" evidence="7">
        <location>
            <begin position="247"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="381"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="433"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ30580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="743" mass="82268" checksum="A2A73465FEF240EF" modified="2011-01-11" version="1">MPDSMEVDPLPSAGMKRKAEEDPEELRASRRIRALDPNVVNKIAAGEIIVAPVNALKELIENSVDAGATALEVLVKEGGLKLLQITDNGCGIQKEDLEILCERHTTSKITAFEDLASIATYGFRGEALASISHIAHLSVTTKTRESECAWRATYLDGKLAPAKPGQSAEPKPTAGRQGTQISVEDMFYNIPTRRRAFRSPGEEFNKIIDIVGRYAIHCKGVAFSCKKHGESGASVSVQASATEVDRIRQIYGSGVANELMHFSTSEDRWGFKATGWATNANYSIKKTTFLLFINHRCVDSTSIKKALEQLYSSFLPKGGRPFIYLSLEIDPARVDVNVHPTKQEVHFLNEDEIIQSICEHIRSKLAEVDASRTFMTQSLLPGSHMMDVTSQDEGDGVPATPARETPGSKRPRRNSNSLVRTDTSLRKITSMLPSATSATPSKASPAAVTTTAAGTPDDNALSSSEHIRYEIVDRPFAPMRLTSVKELRAEVREDMHNDLTDIFATHTFVGIVDERRRLAAIQGGIKLYLIDYGRTCYEYCYQVGLTDFGNFGTIRFTPPLDLREILRMGAEIEKNNVESPDEEFDVDEVVEKVAAQLIERREMLSEYFSLEVSPAGELLTIPLLIKGYTPAMVKLPQFLLRLGPCVDWTGEKACFETFLKELASFYVPEQLPPTIGGDAGNGDEGAGDHDRQIAERRRNVRWALEHVFFPAFKARLVATTPLMKAAVLEVADLKGLYRVFERC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIN5</accession>
    <name>E3QIN5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Proteasome maturation factor UMP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_05789</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the POMP/UMP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094665.1">
        <property type="nucleotide sequence ID" value="XM_008096474.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIN5"/>
    <dbReference type="STRING" id="645133.E3QIN5"/>
    <dbReference type="GeneID" id="24411154"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05789"/>
    <dbReference type="eggNOG" id="KOG3061">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100687_0_0_1"/>
    <dbReference type="OrthoDB" id="15001at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080129">
        <property type="term" value="P:proteasome core complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008012">
        <property type="entry name" value="Ump1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12828:SF3">
        <property type="entry name" value="PROTEASOME MATURATION PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12828">
        <property type="entry name" value="PROTEASOME MATURATION PROTEIN UMP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05348">
        <property type="entry name" value="UMP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0647">Proteasome</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00043974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ30645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="147" mass="16178" checksum="082D64E513791955" modified="2011-01-11" version="1">MAMRIVPAANQPTTFAAGAAAPSAPGVHDTLRAGVGLSAFDAKSNVPTSAHPLESRLKNWEATQENMRMETLRRTFGLAEPIRRQMELKITQNGEWRPLALGGQKPSLHEEILRGKDTSVTWEDVYSGEESVGIVGMHDEMERKLKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJT6</accession>
    <name>E3QJT6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">C6 zinc finger domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_06268</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697353">
        <property type="protein sequence ID" value="EFQ31124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095144.1">
        <property type="nucleotide sequence ID" value="XM_008096953.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJT6"/>
    <dbReference type="STRING" id="645133.E3QJT6"/>
    <dbReference type="GeneID" id="24411633"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06268"/>
    <dbReference type="eggNOG" id="ENOG502SJPD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013866_5_3_1"/>
    <dbReference type="OrthoDB" id="2991872at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053175">
        <property type="entry name" value="DHMBA_Reg_Transcription_Factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38791">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ31124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="425" mass="47457" checksum="4189322FC7D9AF6A" modified="2011-01-11" version="1">MAVAASQAAGTLAIPDVSPRPPPAEPSPASSLARYQTISQPMDDLARTYFMREYIASSPFEYLPRLCPYGLQNNDAMSASILAASFASLSLKVSEPKMMKLARMHYARALSQTNQALSSPERAVEDNTLAAVLLLGLFEAIVYSGQQSLDTWNQHTLGTVELLRLRGTRQFDTPLGRQLFVHSSGNIRTSCAYTKTPVPQRFLKVYENAKPHLDLDDPFLKMTPILDRVATLRSRIASLRDSERREVLYEALDLDAATAKLGEKVPEEWRFTARRPGERSPISYKGMSFRYPSLLILRYWNSLRSIRMFLNDAIWIQSSLALDRGPEPDDETDYEGLQRSASRKMSSLVVEVLGSCGEYLEFSEDRFSVSARCLIWPLSVIAEISSTPPDARLFALDCLDRLGRGGPTLMSVAELTKGDSVQIDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QK12</accession>
    <name>E3QK12_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fungal specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_06344</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697353">
        <property type="protein sequence ID" value="EFQ31200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095220.1">
        <property type="nucleotide sequence ID" value="XM_008097029.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QK12"/>
    <dbReference type="STRING" id="645133.E3QK12"/>
    <dbReference type="GeneID" id="24411709"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06344"/>
    <dbReference type="eggNOG" id="ENOG502S0WX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009353_1_0_1"/>
    <dbReference type="OrthoDB" id="3921198at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF23">
        <property type="entry name" value="THIAMINE REPRESSIBLE GENES REGULATORY PROTEIN THI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="3">
        <location>
            <begin position="272"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="450"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="629"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="451"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ31200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="698" mass="76970" checksum="716C5EA3A2047572" modified="2011-01-11" version="1">MHCMERLLEHYTGKSTLDAETLKTLAESVEKGRAGPEACRAGAEAHVSMEPEVGVEPEAQSQSSDSFKVDDITVQPLENNITHYSGEFSHWNFSMRIKQWIEQCVNDAPDGPKTQFKEYYRPEELQSSSNAVASLSSLPPRYVADFLVHAFFNHAETSYFYVERHWLNEKLDLVYENSASLTRRDVGTVCMILIIFAIGTQYAYLDSRDERGGPPSAAADSSPFSEDTIGIMFYQQACRLVPDVITISSLESVQACLLIGLYTLPLDASGLSYVYLNLAVKLAIQNGMHRKYPGDAIDPVIRETRNRVWWTAYTTEKRIGIFHGRPVSIAAGDVDAELPRDRTDIWPGPAPPNTAHMLATLQLNNALSRIAHQISLFKTYEKHEIPEGMAKLVEMKAQLHNWWNSLPEPTFCKDPTSGPEVFRPTMHLRLEYCLVRMFAGRPFIFPRDSARSTASSSGSPADSAPPPRTSSSTGKIHPRSVLVADCVDAALCVVETCRLLRNSVGLARASYTEFSSCRAALLVIITQCLQKKTDRLRDALREGMAMLKEMSAGGESAKSEMSLIEAFERAISRLDTADDSSSAKESDYARFKKWEMLWKTDMPAQDARSDRGLDAALPIPPHPAMFGRGSQGQGGHVAPGAGRQGTASLPPAMPFFGLDGSLSPMPPALDQFSAMFGNGYVPGFDDLDGSVNGNWMGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QK18</accession>
    <name>E3QK18_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoglycerate mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_06350</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697353">
        <property type="protein sequence ID" value="EFQ31206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095226.1">
        <property type="nucleotide sequence ID" value="XM_008097035.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QK18"/>
    <dbReference type="GeneID" id="24411715"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06350"/>
    <dbReference type="eggNOG" id="KOG4754">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039184_0_1_1"/>
    <dbReference type="OrthoDB" id="496981at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF1">
        <property type="entry name" value="HISTIDINE PHOSPHATASE FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ31206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="300" mass="33948" checksum="C3BBC675B0618203" modified="2011-01-11" version="1">MAAPTSPVCRYKFTVLSGYFVDYHQVAERSPGGKATTQPGLGLLDKPFGDETNQPGAKPWERFAAHVSRLNAESPDGVDYKVVYLTRHGLGYHNVQEAKVGRDEWNRYWSHLDGDGVVTWLDAELVDTGIQQAKELSEFWADATTTEKVPFPESFYTSPLRRCLETSRLAFGALVEAKGEEFRPLVKEGLRERMTDHTCDERSPRKWIESAYPKYMFEPGFTEEDQLWKADRFETAEEHVARKQQVLDEIFSTDANQFVSLTVHSYAIAAILRVGGEEEFRVREGSSIALLIRGEKSVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLB3</accession>
    <name>E3QLB3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">V-type proton ATPase subunit a</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_06940</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the V-ATPase 116 kDa subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697356">
        <property type="protein sequence ID" value="EFQ31651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095671.1">
        <property type="nucleotide sequence ID" value="XM_008097480.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLB3"/>
    <dbReference type="STRING" id="645133.E3QLB3"/>
    <dbReference type="GeneID" id="24412305"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06940"/>
    <dbReference type="eggNOG" id="KOG2189">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005230_0_0_1"/>
    <dbReference type="OrthoDB" id="10264220at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000220">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051117">
        <property type="term" value="F:ATPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002490">
        <property type="entry name" value="V-ATPase_116kDa_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026028">
        <property type="entry name" value="V-type_ATPase_116kDa_su_euka"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11629:SF63">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11629">
        <property type="entry name" value="VACUOLAR PROTON ATPASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01496">
        <property type="entry name" value="V_ATPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001293">
        <property type="entry name" value="ATP6V0A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="422"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="459"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="548"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="578"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="644"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="790"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="101"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ31651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="863" mass="98917" checksum="B1CE8952F8E06666" modified="2011-01-11" version="1">MAPAQDTMFRSANMSMVQLYISNEIGREVVTALGELGLLQFRDLNGEVSAFQRTFTQEIRRLDNVERQLRYFYTQMEKAGIPLRKFDVDAERLANPSTSEIDELAERSQSLEQRVFQLNDSYETLKKREVELTEWRWVLREAGGFFDRAHGNVEEIRASSDNDDAPLLQDVEQHNSAPEVERSFSGMNIGFVAGVINRDRVASFERILWRTLRGNLYMNQSEIPEPLIDPTNNEEIHKNVFVIFAHGKEILTKIRKISESMGAEVYNVDENSDLRRDQIHEVNARLNDVQNVLRNTQQTLNAELIQISQALSAWMVLITKEKAVYNTLNLFSYDRARRTLIAEGWCPTNDLPLIRSTLQDVTNRAGLSVPSIINEIRTNKTPPTYIKTNKFTEAFQTIVNAYGTPTYQEVNPALPVIVTFPFLFAVMFGDFGHAVIMVSAALAMIYWEKPLKKVTFELFAMLYYGRYIALVMGLFSLFTGLIYNDVFSKSLTLFDSAWKWDVPDDYKTGQTLTAKLNDHGYRYPFGLDWRWHDTDNDLLFSNSYKMKMSIVLGWAHMTYSLIFAYVNAKHFKRPIDIWGNFVPGMIFFQSIFGYLVICIIYKWSVNWNDPQNPRNPPGLLNMLIYMFLQPGTLEEGAQLYPGQAGVQVFLLLLAVIQVPVLLFLKPFYLRWEHNHARAKGYRGIGESSRVSALDGDDEDEQGLNGRPSFESDGEGVAMITQDLHSDEEHEEFEFSEVMIHQIIHTIEFCLNCVSHTASYLRLWALSLAHQQLSAVLWSMTLGPALKFEGIVGAIAIVVVFYMWFFLTIAILVMMEGTSAMLHSLRLAWVESFSKFAEFAGWAFTPFSFSTTLEESDELKEYLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLY0</accession>
    <name>E3QLY0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07012</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095888.1">
        <property type="nucleotide sequence ID" value="XM_008097697.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLY0"/>
    <dbReference type="GeneID" id="24412377"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07012"/>
    <dbReference type="eggNOG" id="ENOG502R11U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_976621_0_0_1"/>
    <dbReference type="OrthoDB" id="4841431at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="285" mass="31131" checksum="C005E45E4AE7A33E" modified="2011-01-11" version="1">MRGSPSPSGLLRSQQPASPFTDAQFAIIETLRSQPMPDTPTPLSRHSMTPFARPLKPIALPKNTSLAQRSFSEKTAGPQPSLKRPVAAASKEDAYRPVTSIPCQDPGSRYRPGRIIRSCEERSLPDRRLDLVQAGSADKMIAGPILSNPPGGAKTATMEDLAREAVLGPLFRVTKTPLSPGDMQLPNMLREKRSTGQAHEAYHVGFSPGTEERLDDGLVSRVNTESPNNKGTTPRQWATQETPGKVPLEKEADLRTQMDYYLYFNAPTVGTPHPLAIAIICRDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMD7</accession>
    <name>E3QMD7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_07169</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096045.1">
        <property type="nucleotide sequence ID" value="XM_008097854.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMD7"/>
    <dbReference type="STRING" id="645133.E3QMD7"/>
    <dbReference type="GeneID" id="24412534"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07169"/>
    <dbReference type="eggNOG" id="KOG4178">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_50_4_1"/>
    <dbReference type="OrthoDB" id="408373at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43329">
        <property type="entry name" value="EPOXIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="23"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ32025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="295" mass="33264" checksum="1CF9D2B05CA1240F" modified="2011-01-11" version="1">MPFFKHNENISIFYLEEGPQDAPVVFLIPGITCDLHDWNWQVPFLLQHGFRVITPDPRGQGRSSAPPPTPDIKSYPGPNADPSIVDYYPQSAAEDFIALLQYLNISSAIIIAHSLDTAVAYHLVRLVSVRPDLARAMVILDPLHSISTATVDEHLSDPMTVLPNLARLFDADMHPPTVPAWHNSWTRRRAMQTDMGVIMAQCWACLGDPNAIGRREVSVAQHDDKLMCPRLTLGNSDYWVATERTYLKPSSEHDEIILVGGMGHWFFQHKSMEVNEHLERWFKVVGLLPVQTLSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMG5</accession>
    <name>E3QMG5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Kinase</fullName>
            <ecNumber evidence="4">2.7.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_07197</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the inositol phosphokinase (IPK) family.</text>
    </comment>
    <dbReference type="EC" id="2.7.-.-" evidence="4"/>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096073.1">
        <property type="nucleotide sequence ID" value="XM_008097882.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMG5"/>
    <dbReference type="STRING" id="645133.E3QMG5"/>
    <dbReference type="GeneID" id="24412562"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07197"/>
    <dbReference type="eggNOG" id="KOG1620">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042569_3_0_1"/>
    <dbReference type="OrthoDB" id="338650at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000824">
        <property type="term" value="F:inositol-1,4,5,6-tetrakisphosphate 3-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008440">
        <property type="term" value="F:inositol-1,4,5-trisphosphate 3-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032958">
        <property type="term" value="P:inositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.160">
        <property type="entry name" value="Inositol polyphosphate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005522">
        <property type="entry name" value="IPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038286">
        <property type="entry name" value="IPK_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12400">
        <property type="entry name" value="INOSITOL POLYPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12400:SF103">
        <property type="entry name" value="INOSITOL POLYPHOSPHATE MULTIKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03770">
        <property type="entry name" value="IPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ32053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="391" mass="43284" checksum="44CFBD86E3169AFE" modified="2011-01-11" version="1">MGKKEIPDRADLVDYNHTVAGHAGTMCDADGELFIKPCTQAEIDFYNSAIENHPDFADLMPLFMGTLMLNDPAELSSIEDGVPGPVSSAAAKEELTQAVTGQPSAAAAPDSHTDKDKWVQNKSKRIKTDQAVVLENSGSGFTSPNFLDVKLGERLWADDAPAEKKRRFDEITRKTTHAPLGFRIAGMKVWRGSTMKSELDHEGYKIYDKDYGRTHVNTENVVDNFRKFIFNKTAGIDDDLARAVVQAFLRDLRTVERVLASKESRMYSASLLFVFEGDGDRLKDAIAQNNSAVEKVETELDWEDKPGRPALRVDSGIELIDEDVVTIDAAVNGGDQDDEDDDDDDTPALPKIYSLKLIDFAHAKWTPGQGPDENTLKGVRSLIKIFEEMAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QN05</accession>
    <name>E3QN05_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cytidine and deoxycytidylate deaminase zinc-binding region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_07387</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytidine and deoxycytidylate deaminase family. ADAT3 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697360">
        <property type="protein sequence ID" value="EFQ32243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096263.1">
        <property type="nucleotide sequence ID" value="XM_008098072.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QN05"/>
    <dbReference type="STRING" id="645133.E3QN05"/>
    <dbReference type="GeneID" id="24412752"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07387"/>
    <dbReference type="eggNOG" id="KOG2771">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024580_0_0_1"/>
    <dbReference type="OrthoDB" id="3180714at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052717">
        <property type="term" value="F:tRNA-specific adenosine-34 deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079">
        <property type="entry name" value="CYTOSINE DEAMINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079:SF156">
        <property type="entry name" value="INACTIVE TRNA-SPECIFIC ADENOSINE DEAMINASE-LIKE PROTEIN 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="4">
        <location>
            <begin position="218"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ32243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="436" mass="48328" checksum="583DBAFF9851BFF7" modified="2011-01-11" version="1">MLSAEHPAHPKEGLGRPDDQSVEKGEHAGPDVIQPHVLTDNLIPQQLGRGVLIPLKTTLEIRQDHTIVQALITRAPSTSTNNVVNLIRSMLPEGVANNLPHLRRCAKPADIPAHLKTQFMNDSPEGRQVHTGKSTWIYIMLGEEKDFERHDLTVKLSAIEGLGENLFLTKIPIPAVPPTSQIQAAMWTSQFWPTVYRKNNPLGPHPSMVSRSTETIKDETSLWMTLAHRVALQARKAGVGEAMGAVIVQREGGKSTLVAVAGDARWHQEPSRSGTGNPMAHCALRAISMVAQKLVRHERRVAGHSHSPPILEYDMFQDLPLVEDELTVYNDEHPNTDGYLCHGMEMYLTHEPCVQCSMGILHSRMGKVVFAQRMPLTGGMCSEDRGHDHPELVNCGGGEGLGLFWRRELNWSLLAWEWESSDCVGPLPPVDHRVHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QN21</accession>
    <name>E3QN21_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07403</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697361">
        <property type="protein sequence ID" value="EFQ32259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096279.1">
        <property type="nucleotide sequence ID" value="XM_008098088.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QN21"/>
    <dbReference type="GeneID" id="24412768"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07403"/>
    <dbReference type="eggNOG" id="ENOG502S6B1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078556_1_0_1"/>
    <dbReference type="OrthoDB" id="5430620at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052820">
        <property type="entry name" value="PhiA_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42047">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G03560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42047:SF1">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G03560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180733" description="Secreted protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="208" mass="23018" checksum="3716126533F373F1" modified="2011-01-11" version="1">MLVKLYSVLLALVALAAAGPSVLFAYWSQQTTQIRTCPDGYAINAREGRFWLGEHMPTTYCPDFSGANCPAGNTTVVDSLFRKLRISKPGGQRVYADPDGIISYTPGGNSSVEATPPGSNLDAFRELPVMPFVYGEDDRLLWFYKFGVDPNHSNIYACPDKKRDGMAYLRARWTSKENAVWDSQCFPLDGLLVHPSDDLIGAYEYTVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNH3</accession>
    <name>E3QNH3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_07730</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>5-dehydroepisterol + NADPH + O2 + H(+) = ergosta-5,7,22,24(28)-tetraen-3beta-ol + NADP(+) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:33467"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:18249"/>
            <dbReference type="ChEBI" id="CHEBI:52972"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.14.19.41"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:33468"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="11">Steroid metabolism; ergosterol biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697362">
        <property type="protein sequence ID" value="EFQ32460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096480.1">
        <property type="nucleotide sequence ID" value="XM_008098289.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNH3"/>
    <dbReference type="STRING" id="645133.E3QNH3"/>
    <dbReference type="GeneID" id="24413095"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07730"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023517_0_0_1"/>
    <dbReference type="OrthoDB" id="1372046at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000249">
        <property type="term" value="F:C-22 sterol desaturase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016125">
        <property type="term" value="P:sterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000021">
        <property type="entry name" value="Cytochrome P450 61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24286:SF228">
        <property type="entry name" value="C-22 STEROL DESATURASE ERG5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24286">
        <property type="entry name" value="CYTOCHROME P450 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="13" id="KW-0349">Heme</keyword>
    <keyword evidence="9 13" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="binding site" description="axial binding residue" evidence="13">
        <location>
            <position position="480"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00051023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ32460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="534" mass="59333" checksum="85F654867010E33C" modified="2011-01-11" version="1">MASVVIDTPVAQAELQQTWSNSTSHFPGSLPGFFAGWPTWQYAVTFLLGVVVYDQIMYLKRKGSIAGPAFKIPLMGPFLQALHPKFEEYLAQWASGPLSCVSVFHKFVVLASDRDIAHKVFKSPAYAEPCIVPIAKDILGHKSWVFLQGKAHAEYRRGLMPLFTNKAMATYLPVHEKVLGDYFAKFVAASEAEQGGPTAFMALFREINCALSCRTFFGDYISQDAVEKIANDFYLVTAALELVNVPLSMYVPFTKVWRGKRVADAVHAEFAACAAACKARMAAGAAPTCIVDHWVLHMMESERYRARVAAGDDAGAARPANVIREFTNEEISETLFTFLFASQDASSSATTWLFQILAQRPDVVERVRAENLAARGGDATRPFDLPMLESLTYTNAVVKEVLRLRPPVIFVPYLATKKFPVTPSYTVPKGSMIIPSCYPALHDPEVYPNPDLFDPDRWITGDAESKTRNWLVFGAGPHDCLARRYVPLTMAAMIGKATLEVDWKHHATAKSEEIRVFATLFPMDDCQLSFTRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNS7</accession>
    <name>E3QNS7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GDSL-like Lipase/Acylhydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_07704</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 'GDSL' lipolytic enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697362">
        <property type="protein sequence ID" value="EFQ32434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096454.1">
        <property type="nucleotide sequence ID" value="XM_008098263.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNS7"/>
    <dbReference type="STRING" id="645133.E3QNS7"/>
    <dbReference type="GeneID" id="24413069"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07704"/>
    <dbReference type="eggNOG" id="ENOG502RY37">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065859_0_0_1"/>
    <dbReference type="OrthoDB" id="2141316at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037459">
        <property type="entry name" value="RhgT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43695">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G17250)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43695:SF1">
        <property type="entry name" value="RHAMNOGALACTURONAN ACETYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178674" evidence="3">
        <location>
            <begin position="18"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ32434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="291" mass="30875" checksum="9EC15CACF2291B84" modified="2011-01-11" version="1">MRTSLAVVTSLLGLASALPADGDIIDKRQSVPTIYLCGDSTMAKGGGGSGTEGWGPYLQYSFDSSRAKVDNRAIGGRSARSYTREGRFDDVAGLVKAGDWVVMEFGHNDGGSLTPTDNGRTDCFGDGAQTCQTTYNGVAETVLTYPAYLKNAAQKFNAAGAKVIISSATPNNVWESGTYGWGYDRFFHYAWLAVEQLGGPSKGYYFVPHGEYAAQAMKNLGASIVNANYPNGHTHTAPFLADAMHKAFVLGLRCGTSALASLAKNTTASLTSTYLGPCVDNYNSTVHALLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QP48</accession>
    <name>E3QP48_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 12">Nicotinate-nucleotide pyrophosphorylase [carboxylating]</fullName>
            <ecNumber evidence="5 12">2.4.2.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 12">Quinolinate phosphoribosyltransferase [decarboxylating]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">GLRG_07650</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 12">Involved in the catabolism of quinolinic acid (QA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>nicotinate beta-D-ribonucleotide + CO2 + diphosphate = quinolinate + 5-phospho-alpha-D-ribose 1-diphosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:12733"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:29959"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57502"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from quinolinate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 12">Hexamer formed by 3 homodimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the NadC/ModD family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.19" evidence="5 12"/>
    <dbReference type="EMBL" id="GG697363">
        <property type="protein sequence ID" value="EFQ32636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096656.1">
        <property type="nucleotide sequence ID" value="XM_008098465.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QP48"/>
    <dbReference type="STRING" id="645133.E3QP48"/>
    <dbReference type="GeneID" id="24413015"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07650"/>
    <dbReference type="eggNOG" id="KOG3008">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039622_1_0_1"/>
    <dbReference type="OrthoDB" id="10067394at2759"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00331"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004514">
        <property type="term" value="F:nicotinate-nucleotide diphosphorylase (carboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD+ biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034213">
        <property type="term" value="P:quinolinate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01572">
        <property type="entry name" value="QPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000090">
        <property type="entry name" value="Nicotinate-nucleotide pyrophosphorylase [carboxylating]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.20">
        <property type="entry name" value="Quinolinate phosphoribosyl transferase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004393">
        <property type="entry name" value="NadC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027277">
        <property type="entry name" value="NadC/ModD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036068">
        <property type="entry name" value="Nicotinate_pribotase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037128">
        <property type="entry name" value="Quinolinate_PRibosylTase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002638">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022412">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00078">
        <property type="entry name" value="nadC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32179">
        <property type="entry name" value="NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE [CARBOXYLATING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32179:SF3">
        <property type="entry name" value="NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE [CARBOXYLATING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01729">
        <property type="entry name" value="QRPTase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02749">
        <property type="entry name" value="QRPTase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006250">
        <property type="entry name" value="NadC_ModD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51690">
        <property type="entry name" value="Nicotinate/Quinolinate PRTase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54675">
        <property type="entry name" value="Nicotinate/Quinolinate PRTase N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 12" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Quinolinate phosphoribosyl transferase N-terminal" evidence="14">
        <location>
            <begin position="43"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="Quinolinate phosphoribosyl transferase C-terminal" evidence="13">
        <location>
            <begin position="127"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR006250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EFQ32636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="303" mass="32179" checksum="E01BAE926C52835F" modified="2011-01-11" version="1">MEDVPLEHGSPAHLLPPSWKTQVTAWLAEDTPTFDYGGFVVGNDARTATLWGKSGGIIAGRPFVDEVFAQCGCAVEWHVKEGSHVELRGHGASPKGKMRVATVTGPARGILLGERVALNTLARCSGVASMTRGMLVNLRAAGYAGVLAGTRKTTPGFRLVEKYGMLVGGADAHRMDLSSMIMLKDNHVWSKGSITNAVKAAKSVGGFSLKVEVEVQTEDEADEAIAAGADVVMLDNFTGEGVKVAAKSLKTKWAGKKHFLVEVSGGLTLENVEDYVCNDVDILSTSAIHQGVPHVDFSLKVEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPY1</accession>
    <name>E3QPY1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">AMP-binding enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_08063</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Siderophore biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697366">
        <property type="protein sequence ID" value="EFQ32919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096939.1">
        <property type="nucleotide sequence ID" value="XM_008098748.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPY1"/>
    <dbReference type="STRING" id="645133.E3QPY1"/>
    <dbReference type="GeneID" id="24413428"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08063"/>
    <dbReference type="eggNOG" id="KOG1177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_7_1"/>
    <dbReference type="OrthoDB" id="10253115at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031956">
        <property type="term" value="F:medium-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12780:FF:000003">
        <property type="entry name" value="Long-chain-fatty-acid--CoA ligase FadD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201:SF6">
        <property type="entry name" value="ACYL COA SYNTHETASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201">
        <property type="entry name" value="ACYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="3">
        <location>
            <begin position="44"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="4">
        <location>
            <begin position="470"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ32919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="576" mass="63361" checksum="8A0C0F391252EB65" modified="2011-01-11" version="1">MAVEPSSSVPASEPFVPAQRLSILHGPRDPPLLDLSLGELLELQTYQHGTRECLVIPWTGARWTYNELNQQSLLLAQALLRMGIKAGDRVGVMAGNCEQYAAIFFAVSRIGAILVILNNTYTPSEAMYAVQFSECKILFTTKQIGRLDNTKFLAQLEKEVNGPKVVMIRGDTSGYQTYDELVKSSSRQSPRELHLAMGKVVPHQVCNLQFTSGTTGRPKAAMLTHHNIVNNARFIGDRMRLSPEDVLCCPPPLFHCFGLVLGLMAVITHGAKIVYPAEVFDTKATLKAILEEDCTALHGVPAMFDSLFQAAPDDFKSSKIRTGIVAGAPVPRYLMELMVNRLGMKEFTSSYGLTEASPTCFNAFTDDALGKRLTTVGTLMPHASAKIVDRDGNIVPMGERGELCMAGYQLQAGYWNNSEKTNEVMVRDAAGVLWLHTGDEAVFDNDGYCSITGRFKDIIIRGGENIYPLEIEERLMAHPSISQAIVVGLKDEHYGEVVGAFVQRAENSEKPTFLELKDWVRQRLGGHKSPAHIFWLGEDGVPGNVPLTGSGKVRKFEMAKVGDELLKKSRTVTAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQ01</accession>
    <name>E3QQ01_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ATP-dependent Clp protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_08083</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697366">
        <property type="protein sequence ID" value="EFQ32939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096959.1">
        <property type="nucleotide sequence ID" value="XM_008098768.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQ01"/>
    <dbReference type="STRING" id="645133.E3QQ01"/>
    <dbReference type="GeneID" id="24413448"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08083"/>
    <dbReference type="eggNOG" id="KOG0745">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014218_1_2_1"/>
    <dbReference type="OrthoDB" id="1721884at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050052">
        <property type="entry name" value="ATP-dep_Clp_protease_ClpX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102:SF7">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="204"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="Clp ATPase C-terminal" evidence="6">
        <location>
            <begin position="455"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="164"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="316"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="110"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="40"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="323"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ32939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="585" mass="65368" checksum="713D664CC920D1EA" modified="2011-01-11" version="1">MALFSRPQAYTCARCLVLASTRRTFSASSVARTATTQTRGFNSGFTSSYDPNSEHGRGPMFKKNSFGVPQFYPRDLKKRVDDYVVGQDRAKKTICSTIFNHYQGLRRRRHQEHEERVQREKAERQRYARDRDILEKRDTHPVQGQRDRYSAFQRFPADDEWPPDEFPGHAEATQHLGEGYGSSNGFDGSYLSEEPPAPPQVKIDKSNLLLIGPTGVGKTYILETLSKKLNVPFTISDCNSFTQAGYIGQDVETCVERLLIESNYDIKATEHGIIVLDEFDKLAKRESMNGRDVGGEGVQQALLKLVEGSKVTINVKDNRSSRSTPPITTNYTSSSSTSAPQSTPPQAKVDQYTINTTNILFVFCGAFVGLDKVVVRRVSKPSMGFGSELRGKQSLSGNQHDLPRHLFSHLPHVSTDASASSYTPLDLTTPVDLQTFGFIPELIGRVHNICALSPLSLSDLYRILTEPRNSLVAQYTALFETYPSRLHFTKKALYAIAERAVKAETGARGLKMEMERVLAEPIFDAPMPYVLITEGCVKGTEKAGYWGKDGRMELERRMADEDVEPSSRIPDITFEQFREAGQSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQ96</accession>
    <name>E3QQ96_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_08178</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697366">
        <property type="protein sequence ID" value="EFQ33034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097054.1">
        <property type="nucleotide sequence ID" value="XM_008098863.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQ96"/>
    <dbReference type="GeneID" id="24413543"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08178"/>
    <dbReference type="HOGENOM" id="CLU_2775788_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ33034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="69" mass="7753" checksum="335CDED818F3F662" modified="2011-01-11" version="1">MSVDNCQSHVNMQSHNVMVRMGRWGGSTSLSITFNAESLEYNLAAKFLSEMTSIMLKVLLLYPVTRLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQM3</accession>
    <name>E3QQM3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hemerythrin HHE cation binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_08305</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697368">
        <property type="protein sequence ID" value="EFQ33161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097181.1">
        <property type="nucleotide sequence ID" value="XM_008098990.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQM3"/>
    <dbReference type="STRING" id="645133.E3QQM3"/>
    <dbReference type="GeneID" id="24413670"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08305"/>
    <dbReference type="eggNOG" id="ENOG502SKMW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066708_0_0_1"/>
    <dbReference type="OrthoDB" id="58416at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.520">
        <property type="entry name" value="nmb1532 protein domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053206">
        <property type="entry name" value="Dimeric_xanthone_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012312">
        <property type="entry name" value="Hemerythrin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38048">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38048:SF2">
        <property type="entry name" value="HEMERYTHRIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01814">
        <property type="entry name" value="Hemerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hemerythrin-like" evidence="2">
        <location>
            <begin position="37"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ33161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="257" mass="29792" checksum="BCA317C1D9426458" modified="2011-01-11" version="1">MSQKKPWADGPCELISSTRAGSKEGVKTAGANRMAEDMTIIHNLIIRILNTVYLQCVNVEKSPDDVRDFVSYAIEWAKMVEEHHHIEEETVFPQIEQLTGVPGLMQANVVQHEAFHEGLHAYTGYLDMVQKREEAYSGEKLKGIIDSFMPVLRQHLSDEIGTLLKLGDYDRDWDGWFERLIKELLAKSDDPNLKTTTFPLLLTNRDKTFEDGIYAWWPGLPWFVTLMMRWFLIPKHNNWWRFSSCDHRGVPKELPFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QR06</accession>
    <name>E3QR06_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cellulase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_08438</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697369">
        <property type="protein sequence ID" value="EFQ33294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097314.1">
        <property type="nucleotide sequence ID" value="XM_008099123.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QR06"/>
    <dbReference type="STRING" id="645133.E3QR06"/>
    <dbReference type="GeneID" id="24413803"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08438"/>
    <dbReference type="eggNOG" id="ENOG502QVYM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039562_0_0_1"/>
    <dbReference type="OrthoDB" id="442731at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31263">
        <property type="entry name" value="CELLULASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G14560)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31263:SF0">
        <property type="entry name" value="CELLULASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G14560)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178749" evidence="5">
        <location>
            <begin position="20"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="6">
        <location>
            <begin position="64"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ33294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="416" mass="46679" checksum="767AF71E3D0140CB" modified="2011-01-11" version="1">MGLIRSVWAVCALLLSVHAQKPQLPLFSTSRWITDSSNQRVKLRCINWAGHMEVNLPEGLHKQPIEYLADWIKQEGFNCVRLTYSTDHALNPGVRVRDSFVNGSRAAGVSEADLLSLYDQAVQKNPFLAGPDVTQRDVFERVIDALWDRGVMTILDNHVSRASWCCNLDDGNGWWKDARFYWAANSRYFDTDEWLAGLRQVSLWAKTRPGVAAISLRNELRATWTQIPFAAGQWYDYVARGAKAVHEANPDVLVVIGGLNSATDFTPLRTRSLDTAAWQGKNVWEAHSYSFTVTTPNLGDCNIERAEYGALFGFVLEQGVGYTGPLFMSEFGVAMSGGPEDGLSAEDHAYLTCLVGYLEGNDADWALWAIQGTYYVRNKVVDFEETWGAMDREWKGWRNPAFKGMLGNIFAVTQRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QR51</accession>
    <name>E3QR51_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">O-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_08483</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697369">
        <property type="protein sequence ID" value="EFQ33339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097359.1">
        <property type="nucleotide sequence ID" value="XM_008099168.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QR51"/>
    <dbReference type="GeneID" id="24413848"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08483"/>
    <dbReference type="eggNOG" id="KOG3178">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005533_1_3_1"/>
    <dbReference type="OrthoDB" id="1606438at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712:SF12">
        <property type="entry name" value="STERIGMATOCYSTIN 8-O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="4">
        <location>
            <begin position="198"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ33339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="430" mass="48301" checksum="B228BDFF3D550545" modified="2011-01-11" version="1">MTDHANTAVAQDPSSSILGLAQDVLALTQDMTKYFQANNIAAPTFALSSQDPPDTPDYRRLHASLKSRLEDLLHLIDGPSKWLRAFCCTGYDLGALQIALDFDFFELVPASGDISLEDLAEKAGLDLDRTGRVVRQLMTYRIFDELRPRMISHSSTSLAMRQDEDLRSVVHYSLDEMLKAAADCNISLKANPNESHQNLNPFVTRHGVGIFEYYKNNPDKARRFAKAMAGLRKMDRHLDYLLKDGFNWSAIKGTVVDCGGGNGHISKSLAQLYSDLNFVVQDSNAEMLAEGKESLPDDLRDRVTFSQHSFFDPQPVKNAAAFLIRQCTHNWADRDVVRIFKSFVPGLENSSPDTPLLINDIIIPEPGTWPRHQERIVRQVDMVMLVNCGAKQRNEAEFAALLKEADPRYVIRNVFDNGPLGLLEVYLERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QR90</accession>
    <name>E3QR90_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Involucrin repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_08657</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697370">
        <property type="protein sequence ID" value="EFQ33378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097398.1">
        <property type="nucleotide sequence ID" value="XM_008099207.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QR90"/>
    <dbReference type="STRING" id="645133.E3QR90"/>
    <dbReference type="GeneID" id="24414022"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08657"/>
    <dbReference type="eggNOG" id="ENOG502SEEP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006409_0_0_1"/>
    <dbReference type="OrthoDB" id="5569911at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056703">
        <property type="entry name" value="DUF7801"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029191">
        <property type="entry name" value="Uds1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45615:SF63">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_10, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45615">
        <property type="entry name" value="MYOSIN HEAVY CHAIN, NON-MUSCLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25078">
        <property type="entry name" value="DUF7801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15456">
        <property type="entry name" value="Uds1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Up-regulated during septation protein 1" evidence="3">
        <location>
            <begin position="63"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7801" evidence="4">
        <location>
            <begin position="717"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="130"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="194"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="495"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="555"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="859"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="389"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="145"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="243"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="507"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="556"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="883"/>
            <end position="911"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF15456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ33378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="926" mass="103098" checksum="59B1BF3ACD128AC4" modified="2011-01-11" version="1">MNGYSPGRPSPPRAAGGERPLGGDSLRRDIMNNLEKASLRVDPTSTKLPPSSALVDLKDPIQVHLLTETALTDSKQYRILSQEEVDGAKKQIQSLSLRVEQTRANLAIQTKYRDAAISMAKLYTQPEAGRRRSLLGNNRNSMGESLREAEAERQASEKRVEDLSNELRNLEQRLMESQRNLLEHTAGILQLTHRASKKPASQLPAQMMNGIPGSPESLYAYSNGRNSLEPAGDGSFDEDGPYQNLNNENMSRGQAKVSPLNIPPKAPNREQDTQLQQEAEKLREENARLQSQTDALGAEIDGLKREKAQRLQSVSDTERKLTTFNNSLREVIINFNPTKNGGFRAPPSIATDASVEPGTALGSQLEYLEAGLSAVREEQELQGQSSGALQEAEAAAGEASIALSQTESRLDDLNQQLRDILVAVDPSYPDVANSGLDSQFDWLQRAISVVDEEMKKTAGLSAVKKQDEEQVEAALVGLWETIQSGFVNIQKQKADRRRTRMEQGVSENEDDMSEDEAVDTTEPYSLSAFSAKVQWLYRQATSLKEQKSVLKRQIKQQRELNSKSDSQRDEELRAKQEQLEQLRAAQMRSEEEKTLELTLKQDQLDQLRSLLERSEEEVAEAQEKLAKTQKEAEAAMTTRMANESSAAKTQDEIKQRDAKIASLEASTKEAQTTLASLNTNVQELNDKLSRANEEIALLTTKLAGAEKAAVEKQQEVAAKDKEVKEKEEELDRFNMMIVELKTELTIAQAELDGAYGSRKERADQAAAIKSSVEAAQLKTEVDRLKEELSSTLKELESITAETIKAEREKFDVESKLDDALAVKSNLEGEISSLKDQLEAEVDNSRVKLAKLQEELDSERLKVTPGAGARGAGASMLSEQFRTTMREERKKFQEDLREEQGKRRKLEEELQKIKKSQGPGRSPLSPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3QR96</accession>
    <name>E3QR96_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">HMG box protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_08663</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697370">
        <property type="protein sequence ID" value="EFQ33384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097404.1">
        <property type="nucleotide sequence ID" value="XM_008099213.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QR96"/>
    <dbReference type="STRING" id="645133.E3QR96"/>
    <dbReference type="GeneID" id="24414028"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08663"/>
    <dbReference type="eggNOG" id="KOG0527">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010453_0_1_1"/>
    <dbReference type="OrthoDB" id="6247875at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01389">
        <property type="entry name" value="HMG-box_ROX1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.30.10:FF:000041">
        <property type="entry name" value="HMG box family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050140">
        <property type="entry name" value="SRY-related_HMG-box_TF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10270:SF320">
        <property type="entry name" value="BOX TRANSCRIPTIONAL REGULATOR, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G10820)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10270">
        <property type="entry name" value="SOX TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HMG box" evidence="6">
        <location>
            <begin position="94"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="4">
        <location>
            <begin position="94"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="155"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="273"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="531"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="196"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="218"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="305"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="362"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ33384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="678" mass="73729" checksum="D6CF955477BF8606" modified="2011-01-11" version="1">MADVVSTPRPRRSTSSSGGNSAHSVMERRTSEETDEGPDSVGSAGSRASRKRAASIDIEEANSSRGREFSLESGPTGSESGKDYICLCTPALKVPRPRNAFILYRQHHQAQVIAQHPGLSNPEISKIIGEQWRIQPDDVKESWKKLAEEEKIRHQRQYPDYRYQPRRGGRPGSRPSLSSGADTGRCSKCGGRFIATPRTPTTPFGTPTAAKSNMSPPHPRDGRDGDGDHHRHTLPGAKQQYQFQPNNLRDVEEEYESMSPSLELKRRRFNGMGHYQAVSSPGPYTGHPLSRQPRSSLSMPPTPPLAGYGPLPGPSALARTGNMAPPPRPHHPAYAGPSRGPGFDESLRLPPLQTQTSPPFNRENDANDRPSAHPATGLGITNPRDSYAQSLEAMIMTIPFLSKLKVLQKISPTLTPPGPSSPDMEVRGAVIAVEGADARQLEQVGTAIHRSLLGLAEIDLKTWSDGPNMAAPILSAEEVANMNDTASVGSSRKSSHSQPSLQTSELFANYMQTMMKWHGKSREIVKHVSTRPVSGLSGSPLTRRASDGDAGGFGQSSVSLPGTDKTPIALLPAGFSLSISDKYACMIPIADSYAPVDHWQWMSTLWRGIVGPDLVIYVKSVVEDEVTRAGAVEFRGPGVMVVRIAHNKSLDEKTERRISFEVVEWIRGGSYQEGFGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRJ6</accession>
    <name>E3QRJ6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_08763</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697371">
        <property type="protein sequence ID" value="EFQ33484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097504.1">
        <property type="nucleotide sequence ID" value="XM_008099313.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRJ6"/>
    <dbReference type="GeneID" id="24414128"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08763"/>
    <dbReference type="eggNOG" id="ENOG502RPT7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1959413_0_0_1"/>
    <dbReference type="OrthoDB" id="4833021at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ33484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="128" mass="14540" checksum="06805D68E7105DC3" modified="2011-01-11" version="1">MDTHAQPTSWYDAMMTYSLLSSAYPTVVRYISGAFIALGFMFIIPIILLITVDFGIYIYRICWSRPWNRYQNQPSHPYEQRLQQLQLHKLTPEVVEGTPIVTSTATGAARKRRQHLSKSGDGNDVSSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRL8</accession>
    <name>E3QRL8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_08785</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697371">
        <property type="protein sequence ID" value="EFQ33506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097526.1">
        <property type="nucleotide sequence ID" value="XM_008099335.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRL8"/>
    <dbReference type="STRING" id="645133.E3QRL8"/>
    <dbReference type="GeneID" id="24414150"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08785"/>
    <dbReference type="eggNOG" id="KOG0062">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_36_6_1"/>
    <dbReference type="OrthoDB" id="2110130at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022626">
        <property type="term" value="C:cytosolic ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071232">
        <property type="term" value="P:cellular response to histidine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042327">
        <property type="term" value="P:positive regulation of phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071264">
        <property type="term" value="P:positive regulation of translational initiation in response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043335">
        <property type="term" value="P:protein unfolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006448">
        <property type="term" value="P:regulation of translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000104">
        <property type="entry name" value="ATP-binding cassette sub-family F member 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000882">
        <property type="entry name" value="Translation initiation regulator (Gcn20)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF117">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="198"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="530"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="122"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ33506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="750" mass="82703" checksum="F4C49FED6C34A2E1" modified="2011-01-11" version="1">MDAEIRTVLPNIDPVLSEYSVGYLTHASTIYSDEEDQSGPSPIAEAAATVTELLLSASGKPDAKLQDRIEKLVEKWVEKYTEANGGMRSGPSAVKRLDETFQVSSQRNMSSTLAVSTGAVDLESANARKVESKVDRKKLEKAERKIAAKQQKKTFKTVEYEASRLLDEPESTQSYEEFYMAVNPLQIGGSGANKTKDIKLDNIDVSIGGQRIVTDTDLTLSYGHRYGLVGHNGVGKSTLLRALSRRELPIPPHITILHVEQELTGDDTPAIQAVLDADVWRKVLLKEQAEITQKLADIESQRTGLADTSADAARLDKEREAQDSRLGDIQGKLAEMESDKAESRAASILAGLGFSAERQQYPTKTFSGGWRMRLALARALFCEPDLLLLDEPSNMLDVPSIAFLSNYLQGYPSTVLVVSHDRAFLNEIATDIIHQHSQRLDYYRGANFESFYATREERKKTAKREYENQMAQRAHLQAFIDKFRYNAAKSSEAQSRIKKLEKMPVLEPPETEYSVHFKFPDVEKMTPPIIQMTGVTFGYSKDKILLRNVDLDVQLDSRIGIVGPNGAGKTTVLKLLIGKLSPTSGLISQNPRLRVGFFAQHHVDALDLTMSAVGFMAKEYPGRTDEEYRRQLGAFGITGTTGLQKMAVLSGGQKSRVAFACLALTNPHILVLDEPSNHLDIEAMDALASALKEFQGGVLMVSHDVTMLQTVCTSLWVCDGGTVEKFPGDVQAYKKRIASQADAAGVVKAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRP2</accession>
    <name>E3QRP2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Crh-like protein</fullName>
            <ecNumber evidence="16">3.2.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">GLRG_08809</name>
    </gene>
    <organism evidence="22">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell envelope</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Lipid-anchor</topology>
            <topology evidence="3">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the glycosyl hydrolase 16 family. CRH1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.2.-.-" evidence="16"/>
    <dbReference type="EMBL" id="GG697371">
        <property type="protein sequence ID" value="EFQ33530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097550.1">
        <property type="nucleotide sequence ID" value="XM_008099359.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRP2"/>
    <dbReference type="STRING" id="645133.E3QRP2"/>
    <dbReference type="GeneID" id="24414174"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08809"/>
    <dbReference type="eggNOG" id="ENOG502QQ71">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027506_3_1_1"/>
    <dbReference type="OrthoDB" id="4781at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02183">
        <property type="entry name" value="GH16_fungal_CRH1_transglycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017168">
        <property type="entry name" value="CHR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF68">
        <property type="entry name" value="GLYCOSIDASE CRH1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037299">
        <property type="entry name" value="Glycosidase_CRH1_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="10 18" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="8 16 21" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="9 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 19" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="19">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180720" description="Crh-like protein" evidence="19">
        <location>
            <begin position="22"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="20">
        <location>
            <begin position="44"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="17">
        <location>
            <position position="121"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="17">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="18">
        <location>
            <begin position="27"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00038074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR037299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR037299-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR037299-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EFQ33530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="367" mass="38381" checksum="58D86439D443A3A7" modified="2011-01-11" version="1">MFSKILSVATVALATTSLVSAQTFTTCDPTKKTCPADPALGKSVDIDFTKGNDDSFFRQLDGTDVKFEDGGALFSISKESEAPTMASKKYIFFGKVDVVLKAAPGQGIVTSIVLQSDDLDEIDWEWVGGDNTQVQTNYFGKGDTSTYDRGAFHTVSNPLSDYHTYTIDWTQDSVKWIIDGALVRELKYADAKGGAMFPQTPMEVKIGTWVAGRKDAPKGTVEWAGGYADFSKGPSNAYYKSISITDYQGNKGAKGAKQYVYGDRTGSWESIVIKTDGGDDDSSSSVSKTATKTTLSTVTATGSSSASATASSDASATEDASASATGASDSGSAASAAAPSTVAASSGFATKANLALGAIGLFFTFML</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRS9</accession>
    <name>E3QRS9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_08846</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MSOX/MTOX family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697371">
        <property type="protein sequence ID" value="EFQ33567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097587.1">
        <property type="nucleotide sequence ID" value="XM_008099396.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRS9"/>
    <dbReference type="STRING" id="645133.E3QRS9"/>
    <dbReference type="GeneID" id="24414211"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08846"/>
    <dbReference type="eggNOG" id="KOG2820">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007884_0_1_1"/>
    <dbReference type="OrthoDB" id="2219495at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050031">
        <property type="term" value="F:L-pipecolate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004657">
        <property type="term" value="F:proline dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008115">
        <property type="term" value="F:sarcosine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045170">
        <property type="entry name" value="MTOX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10961">
        <property type="entry name" value="PEROXISOMAL SARCOSINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10961:SF46">
        <property type="entry name" value="PEROXISOMAL SARCOSINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="6">
        <location>
            <begin position="17"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ33567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="493" mass="52606" checksum="F0DA47D5B2C1211B" modified="2011-01-11" version="1">MSSDQAAAAEEPAPSSILIIGSGVFGLTTAYELAQRPRYASTTITVLDRSPVPGPSQDAASVDSSRIIRADYADPAYARLAAEAQIEWRKTEHPSDLGAEGRYSQSGLCLVADPTPMAASAYASSAPSPSPPRTVNTNGQAKLKAKKTSLEYVRESYSNVVSLAGADGDRIIRELPTPTAIKDFLGTPIAPGTWGYINPLAGWADAGAAMSYLAAKVQALGRVNFVSGTATHLNYGPDRRTVTGATLDNGVILSADLVVVAAGAWTGQLIDLSGQAIATGQAVGYIDITPSELEVLRKMPVTLNFSTGLFMIPPAGLQLKVARHAFGYLNPTPIPHPSPSAPSSARSTVSLPATHLTDPRLKFPKEGEAALREAVRTIVPIPAIHNRPFAQTRLCWYTDTQSGDFLVCHHPEAKNLFVATGGSGHGFKFLPVLGREIVNVLERRGDEVFTEKWRWRETKSKTGVTDLYEHIMTEDGSRGGIPGLLLKKEQAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QT29</accession>
    <name>E3QT29_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Carboxypeptidase M14B</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Carboxypeptidase MCPB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">GLRG_09161</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Extracellular metalloprotease that contributes to pathogenicity.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the peptidase M14 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697375">
        <property type="protein sequence ID" value="EFQ34017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098037.1">
        <property type="nucleotide sequence ID" value="XM_008099846.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QT29"/>
    <dbReference type="STRING" id="645133.E3QT29"/>
    <dbReference type="GeneID" id="24414526"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09161"/>
    <dbReference type="eggNOG" id="ENOG502SM8M">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026103_1_0_1"/>
    <dbReference type="OrthoDB" id="3626597at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705:SF83">
        <property type="entry name" value="INACTIVE METALLOCARBOXYPEPTIDASE ECM14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705">
        <property type="entry name" value="PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52035">
        <property type="entry name" value="PEPTIDASE_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="7 14" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178807" description="Carboxypeptidase M14B" evidence="14">
        <location>
            <begin position="20"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M14" evidence="15">
        <location>
            <begin position="70"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="13">
        <location>
            <position position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00041263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00042017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS52035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EFQ34017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="550" mass="59441" checksum="E9AD05ECACB62CFC" modified="2011-01-11" version="1">MRFQGATALGLLHAGLTAAKLTYASNQARVFPDSKAVAANFPEVEDVELFSPAFANPESVPSGFANGTSSPTDEATLDHFLRTLAARNEWMTYRSSDFRSEEGRLIPYVYLSTSESVPDGNGGLESRANAIAPGKVRIWMQGGVHGNEPAGDQALLALLGKLDANATWAASVLGKVDIMMLPRYNPDGVAYFQRCLATNYDPNRDHTKLARQQTRDIKRLVMGFAPHVGVDCHEYSPADPLGADGQWVEAQDGQFSAMKNSNIHQDIRSLSEAVFATAVAAAMGRRGLRWGPYATGHTGTDDVVMKETTGDAKIGDSAVALGQAVVFLTETRGIGLADQHWRRRVAAGLTMVEAIIQTAADRADEVYATVEGARAKFIAGGDDIVVTESARPTNISWQFIEAATGALVDVPVRFLNTTPVVAGLTRRRPEAYVFSRAWVDVAERLRVTGVDVRELRADFRGEVEALNVTGADAVDEGGARFEGVSRTKVTTETVRKEVRILAGGFWVGTRQKNAAHAFVTLEPEGIDSYATFNILPVSVGDEYPVYRVMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QT89</accession>
    <name>E3QT89_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">GLRG_09221</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="3"/>
    <dbReference type="EMBL" id="GG697376">
        <property type="protein sequence ID" value="EFQ34077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098097.1">
        <property type="nucleotide sequence ID" value="XM_008099906.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QT89"/>
    <dbReference type="STRING" id="645133.E3QT89"/>
    <dbReference type="GeneID" id="24414586"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09221"/>
    <dbReference type="eggNOG" id="KOG0331">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_1_5_1"/>
    <dbReference type="OrthoDB" id="196131at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000464">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00268">
        <property type="entry name" value="DEADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000008">
        <property type="entry name" value="ATP-dependent RNA helicase RhlB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044742">
        <property type="entry name" value="DEAD/DEAH_RhlB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 13 17" id="KW-0347">Helicase</keyword>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="15">
        <location>
            <begin position="213"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="16">
        <location>
            <begin position="419"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="66"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="97"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="112"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EFQ34077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="603" mass="65916" checksum="7F2895DB377F088E" modified="2011-01-11" version="1">MAATKRSLADTEAEAEVTTKKQKVKDLAVGGDVDSDEVAELKKQKKKEKKERKKEKKDKKDKKSKSAAAADQDGEAPAAAAAAEEAKAETEEEKAERKRQKKEKKRKEKEAAAQSSSSNNNGSAAVPVVTASGPTPTAAVLGGYQQAAALTALPQSEVDAFLTAENITVTDPVDNPTALRPILEFSYLPETDLIKKKPFSAYKKPTPIQSASWPYTLSRRDVIGVAETGSGKTMAFALPLVEGISKIKKRCIKAVVVSPTRELAMQTQEQMEHVSSLLGLKSICIYGGASKDDQRALLRRGADVIVATPGRLKDFMMDGTISLQDVKFAVLDEADRMLDKGFEEDIKMILGDMPAREARQTVMFTATWPASVRKLAESFMVDPVKVTIGSSGKETANGAVELQANTRITQRVEVVDPRAKEQRLLQLLKQWQATASQKNDRILVFCLYKKEATRVEAFLQQRGIRVGGIHGDLRQEQRTRSLEAFKAGTTPVLVATDVAARGLDIPEVKLVINVTFPLTIEDYVHRIGRTGRAGKTGEAITLFTEHDKAHSGSLINILKGAKQPVPDELFKFGTTVKKKAHSTYGAFFKDVDMTKKATKITFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QT94</accession>
    <name>E3QT94_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kinetoplastid membrane protein 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09226</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697376">
        <property type="protein sequence ID" value="EFQ34082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098102.1">
        <property type="nucleotide sequence ID" value="XM_008099911.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QT94"/>
    <dbReference type="STRING" id="645133.E3QT94"/>
    <dbReference type="GeneID" id="24414591"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09226"/>
    <dbReference type="eggNOG" id="ENOG502SPMP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076797_0_0_1"/>
    <dbReference type="OrthoDB" id="1896086at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037460">
        <property type="entry name" value="SEST-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37981">
        <property type="entry name" value="LIPASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37981:SF1">
        <property type="entry name" value="SGNH HYDROLASE-TYPE ESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005673549" evidence="1">
        <location>
            <begin position="21"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="306" mass="33868" checksum="8CA0B1811E4328B5" modified="2011-01-11" version="1">MLLSWWQCATIAVAIGPVSGLAVPYYSSNASMPILSSRQSLEDFDPDDLSYIQKLAAIGDSYSAGIGAGNRLGSIVNALNPQSNWACSRYDQSYPSFVDGDVRLGNRATRNFQFKSCSGATSSEVIEHQIPKLNGNQDVILLSARQLAESGRLIDSATFAGNLDKVIAAAQSKLSLKYAKFFATDMSSECDDVTWSTWLNELYNKFKLEKAYLTQGRRQKMNELVEKVNKKLAEAVERAGNSVKFIDYDKYVGYYGGRYCEAGVDESTSEAKTRTGLMFYELNTWDPLGSSPWKRSNDDALKGKFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTI4</accession>
    <name>E3QTI4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09316</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697377">
        <property type="protein sequence ID" value="EFQ34172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098192.1">
        <property type="nucleotide sequence ID" value="XM_008100001.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTI4"/>
    <dbReference type="GeneID" id="24414681"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09316"/>
    <dbReference type="HOGENOM" id="CLU_2739865_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="71" mass="7687" checksum="09516C575726FD6A" modified="2011-01-11" version="1">MDLESVWPRLARESLRGSGITPCYSHRQTEINTLSQSRDDALMMGMGESGLASSGGVDDVDSKMEAPTRPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTJ5</accession>
    <name>E3QTJ5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Ferric reductase like transmembrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_09327</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697377">
        <property type="protein sequence ID" value="EFQ34183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098203.1">
        <property type="nucleotide sequence ID" value="XM_008100012.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTJ5"/>
    <dbReference type="STRING" id="645133.E3QTJ5"/>
    <dbReference type="GeneID" id="24414692"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09327"/>
    <dbReference type="eggNOG" id="KOG0039">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005646_3_0_1"/>
    <dbReference type="OrthoDB" id="167398at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043020">
        <property type="term" value="C:NADPH oxidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016175">
        <property type="term" value="F:superoxide-generating NAD(P)H oxidase activity"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:monoatomic ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042554">
        <property type="term" value="P:superoxide anion generation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000103">
        <property type="entry name" value="NADPH oxidase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000004">
        <property type="entry name" value="NADPH oxidase isoform 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050369">
        <property type="entry name" value="RBOH/FRE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972">
        <property type="entry name" value="NADPH OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972:SF153">
        <property type="entry name" value="SUPEROXIDE-GENERATING NADPH OXIDASE HEAVY CHAIN SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01169">
        <property type="entry name" value="NADPH_oxidase_subgroup_(NOX)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="132"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="169"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="12">
        <location>
            <begin position="268"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ34183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="568" mass="65382" checksum="1D8A380D1A975C2F" modified="2011-01-11" version="1">MDYYTEKPSERSRWTPLTRMLLSGEMTQERQKELTMRERFDRWMINEGYRRVFVFVFLILHGLVFAFATVNFSLKDNLQIARNTFGPTFIIARAAALVLHVDVALVLFPVCRTLISLARQTPLNGIIQFDKNITFHITTAWSIVFFSWVHTIAHWNNFAQIAAKNNLGIYGWLLANFVSGPGWTGYVMLIALMGMVLTSVEKPRRANYERFWYTHHMFIIFFFFWSIHGAFCMIQPDFAPFCTSIGTSAIGVFWQYWMYGGFVYLAERVAREVRGRHNTYISKVIQHPSNVCEIQIKKEHTKTKAGQYIFFCCPAVSLWQYHPFTLTSAPEEDYISIHMRVVGDFTREVSTALGCDWDKKKDDASKVVGVNSDSSEVDPALRRVLPRVYVDGPFGSASEDVFKYEISVLCGAGIGVTPFASILKSIWYRMNYPQQKTRLSKVYFFWICRDFGSFEWFRSLLLAIEAQDVDNRIEIHTYLTAKIKADDATNIMINDANADKDTITGLRSPTNFGRPNWDMIFRGIRKLHSPAEAGVFFCGPKGLGSSLHIYCNKYSEPGFSFVWGKENF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>E3QU02</accession>
    <name>E3QU02_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Mitochondrial dicarboxylate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_09484</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697379">
        <property type="protein sequence ID" value="EFQ34340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098360.1">
        <property type="nucleotide sequence ID" value="XM_008100169.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QU02"/>
    <dbReference type="STRING" id="645133.E3QU02"/>
    <dbReference type="GeneID" id="24414849"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09484"/>
    <dbReference type="eggNOG" id="KOG0759">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_14_1_1"/>
    <dbReference type="OrthoDB" id="448427at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050391">
        <property type="entry name" value="Mito_Metabolite_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45618">
        <property type="entry name" value="MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="55"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="153"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ34340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="256" mass="27876" checksum="6F94FD7166DEB87E" modified="2011-01-11" version="1">MYRFAARDGSFSLWSGLSASIFRQTTYSTARFGLNNYFAQRVKQWTGKEKLTTAMTISCAGLSGGMAGLVGNPAEVVLVRMCADGAKNVGERFAYSNAIEGLYRIGREEGLGAFTRGISANVVRSVLMSNKLKHENRYSTAKQMLLKNTEMKDDIKTHAVASLFAGTAATTICAPADVLKSRIQSAAAGGPGANSLLRIVQSGLREEGAIFLMKGWTPAWLRLTPNTVLTFVFMEQLRQLTQWQFAAPVEVETIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QU17</accession>
    <name>E3QU17_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09499</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697379">
        <property type="protein sequence ID" value="EFQ34355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098375.1">
        <property type="nucleotide sequence ID" value="XM_008100184.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QU17"/>
    <dbReference type="STRING" id="645133.E3QU17"/>
    <dbReference type="GeneID" id="24414864"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09499"/>
    <dbReference type="eggNOG" id="ENOG502SICY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002639_3_1_1"/>
    <dbReference type="OrthoDB" id="47007at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF9">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="228"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="765" mass="85684" checksum="D4D1F28220C62F7C" modified="2011-01-11" version="1">MTTKIVPLSLDDALKNGSHIDTTTKAKSFDFFDMLGTAGCLLNCAGYALRQKLSPDAIKLSQASHEEVVRHGKHRAVQGKLFTYGHLEKSASNGCGSCKAVKTILDAVPCHHYGGLLPSTAIRWTVRHSGTLELAAPDGKEYYLRLLNLAGSVNVFRRFPSTNGLAGDTASPISFHRIRNWLDDCETGHEQCGKGIDTELPTRLIDVTQPGDRAGVRLVETAGQIGTYICLSHCWGKIKIKSITQKDSLRRRLNLIPWDLLPPSFQHAVELTRKLGVRYLWIDSLCIIQDDKDDWEKEAAQMVNVYRNSYATIAVSWSHDPQGGCYSRTIPSFFFKMTNPDGDDFAIALGIGAKRDSTSEYGRVQAYLPLFNRAWCLQERLLSRRIIHCNYGEMAFDCGNGFSCECGGKQHYNWHNVIDLAGTYTPLRSRSTYLALLNNHRTASSSTAIMTEKAGKIDPYERWHRVISEYTCLNLTKTSDMLPALSGLAHETAELVGDDDAFLAGLWMNNLEQDLMWRVVAVADWRYQRAKMLKRGWVAPSWSWASTGSGCKVGHPVFQGAEVLDYKTPGIKAKSCKVICPPAGADPFGSVSYGLLQVTAKRMPVLIQRPCSRWDVKRRWTDRVYGRFLLYAREDQREWQDCLPVTGAAPLEFGPVKSELWVDPSVERMEGCFLRNGDPAAHPGPCRHCLFLPAELLYVKGLKTDKGTLSTRTRDFFLVVARDATSSYMRVGMLEVICGNRGERNDWFERVWEKTATPEALVTIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QU44</accession>
    <name>E3QU44_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09526</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697379">
        <property type="protein sequence ID" value="EFQ34382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098402.1">
        <property type="nucleotide sequence ID" value="XM_008100211.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QU44"/>
    <dbReference type="GeneID" id="24414891"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09526"/>
    <dbReference type="eggNOG" id="ENOG502T4JV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_882801_0_0_1"/>
    <dbReference type="OrthoDB" id="4849504at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="315" mass="34752" checksum="17657F9CF97088B1" modified="2011-01-11" version="1">MKSQLRSSQPATPRRQHQPLESTAGPSQRPDLPFQRTITIRRLCQNPLRCDKGPGLHSHLAQIPRSVAAGLGVTKQKRTRLEQGESRTPNDKRTRAEPERQQQAPDLPLEEGSSGACASRTEDRDRRPGDRLSVRTVEREEQRSALGTSSARPADRRRSGSERQQVPDQALYDCQIEEAFRGLLEKLVHWEISTPEDVQAMKDELDKMAITPAPAPPAAEAEEERSLGPDAVGNEMLPGTEGLEESDDQEQEANKEAESLAFDVVYTLDAGDPGDEYVVYEVEGCLGKAGEDGAGMCHVSYKEVPADMDGEYVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUS7</accession>
    <name>E3QUS7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GMC oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_09759</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697382">
        <property type="protein sequence ID" value="EFQ34615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098635.1">
        <property type="nucleotide sequence ID" value="XM_008100444.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUS7"/>
    <dbReference type="STRING" id="645133.E3QUS7"/>
    <dbReference type="GeneID" id="24415124"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09759"/>
    <dbReference type="eggNOG" id="KOG1238">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002865_4_1_1"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF80">
        <property type="entry name" value="GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178895" evidence="2">
        <location>
            <begin position="23"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="3">
        <location>
            <begin position="356"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ34615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="660" mass="71515" checksum="B2E1B7635579CAF6" modified="2011-01-11" version="1">MAVLRSITALTALLLLPLTTLAHPEPSNRTYDYIVVGSGPGGGPLACNLARAGHSTLLLEAGDDQSSDVRTIIANGGYMVTPADGWFFFVKHHSDEETERRNNHLTWRFANGSYWVGNAARAPEGAELLGVYYPRGATVGGSSVTNAMATWLPSDGDWDFVQNVTGDTSWNHSNMRRIFERIERNNYLRRGTPGHGFDGYFETNLGNGSQYIRNPGVMDVLKSHVRSIGQDPDKLIEMLVSDGNFLSENRDTTEGLWGLSSHATERWERYSARTLILETLSAKNPDGSPKYPLALSPNSLATKVLFNETSVRKPRAIGVGYLVGNSIYGADLRRSASGTGETARAFASREVIVAGGAFNSPQILQLSGIGNKADLEALGIKVVADLPGVGRNLQENQEFPVVGHAQLNLTAIASPNEPTCAKGTPGDPCEALWRQGKGPYMRPGYNSNALLLKSNFSLNGERDVFIFSWPNAFRGFWPPVKQPELVDPPTTMGFSVVKMHPQNKAGYVKLRSADPTEPPEINFELYKEGAETDLGALAEIVAWGRRSMSNVQGPWGPLEPAEPPCSQVRSDGGCGDADAESDKKWIREQTFGHHPTGTCKVGAEGDRMAVLDSKFRVLGVEGLRVVDASVFPRAPGAFPVVATFIISQKASDVILSEVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QV36</accession>
    <name>E3QV36_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_09870</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697383">
        <property type="protein sequence ID" value="EFQ34726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098746.1">
        <property type="nucleotide sequence ID" value="XM_008100555.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QV36"/>
    <dbReference type="GeneID" id="24415235"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09870"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_4_4_1"/>
    <dbReference type="OrthoDB" id="3639251at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF64">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="199"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="242"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="278"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="309"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="339"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="374"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="1"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="402"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ34726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="445" mass="49738" checksum="92D4CBAAC51D4FCE" modified="2011-01-11" version="1">MKEDLELFGNELNYFTTFFNIGYMIMLYPSCIVISHFGPSRWLPACELIWGVLTCCLSVVSSAKQVYGLRFLIGFFEGTAWPGYFTLISQWYMPHEVALRMSLYNIAQPAGAMLSGAMQGALSTNFEGLHGRSGWRWAFIINGVCTIAVAIAAFFILPGYPERPNPLSKFYLKPKHIDIALARARRVGRKPQIGITPISFFRCFTFWQLWAFAIAWCIGGNFTPANYFNLWLKSLKNSDGSVKYSIAMINYLPIIGQAIQLVAELLFSGFSDYFGVRLPFLLLHSVINISSHIILIVRPSNERAYMAGWYMNYIGAVSTMLLCSWASAHLQGEPQVRTVLFASGTILSYLMSAFIPLAAFPASEAPQWRIGSKLYLGFALVSSVMFVGIHFALQWEEKRKAKDAVKQDSTGEPDNADAGVKSVLEKSDSTAIGKKSMGKFHDRPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>E3QV43</accession>
    <name>E3QV43_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Protein kinase C-like</fullName>
            <ecNumber evidence="2">2.7.11.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">GLRG_09877</name>
    </gene>
    <organism evidence="25">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="25" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="25">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.13"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.13" evidence="2"/>
    <dbReference type="EMBL" id="GG697383">
        <property type="protein sequence ID" value="EFQ34733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098753.1">
        <property type="nucleotide sequence ID" value="XM_008100562.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QV43"/>
    <dbReference type="SMR" id="E3QV43"/>
    <dbReference type="STRING" id="645133.E3QV43"/>
    <dbReference type="GeneID" id="24415242"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09877"/>
    <dbReference type="eggNOG" id="KOG0694">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_54_0_1"/>
    <dbReference type="OrthoDB" id="63267at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010494">
        <property type="term" value="C:cytoplasmic stress granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000935">
        <property type="term" value="C:division septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030427">
        <property type="term" value="C:site of polarized growth"/>
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    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
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    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <keyword evidence="9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="REM-1" evidence="23">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
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            <begin position="156"/>
            <end position="233"/>
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    </feature>
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        <ligand>
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        </ligand>
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    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Coils"/>
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    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
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        </source>
    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="EFQ34733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1157" mass="129401" checksum="0DFF17D9BE71D3A2" modified="2011-01-11" version="1">MNDEDAIQNILKKIEREKALLNAANAMRAQTNNEAVRSRLDSQMRDGRRNLQFFEEKLREAQLRRGMDNMSLGSPTGDSRPLSGDMDDVPPPPPKDSGWEQRGGYGAGSATSGGNVQYSQIGGHADLMPPRHPYANPGPSSVPKSRPNFTKLDLIKYDTPYLGPRIQLMLSQIQFKLNVEEQYLKGIEKMVQLYGMEGDRKSKADAAARRVESKQKILLLKQAMKRYEELHIDMDTSDAQDDDSINVPNLRKPLTGQLSIRVGQIKDVDHASMSRFSRGPETFIAVKVEDNVVARTRVTRTDKWEAEYHTIDVDKANEIELTVYDKPGEHAIPIAMLWVRISDIAEEMRRKRIEAEINNSGWVSADRMGAPPSQFPMNPPQQQQSFGGPPSSPGLAQPGAQGQQAPGGMPNPPIAHQPIDGWFNLEPAGQIQLSLGFLKQNNARRPVNLQGLGRVGAVRQRKEEVHEMYGHKFVQQQFYNIMRCALCGDFLKYSTGMQCEDCKYTCHTKCYASVVTKCISKSNAETDPDEEKINHRIPHRFQAFSNMTANWCCHCGYILPFGKKNCRKCAECGLTAHAACVHLVPDFCGMSMAVANQILEGIKTTRMITKNKTSSSLSERTLRKPTSPTSTLGSPPHSGGQAHYAGGSPEATEAAKLMYQQQSPSGQRPSHPDRTASSTAAAAAATAAMSGTIASQPKSHSQDYGQYGGHPGYPPQAEQEDPYGGRKYNPADYAAVNQQAASYAQQSPVQQQQQRPVQQQQQQQQQQPLPQQYQQPTQQQMYQQQPVSSPKLQEPPQISPISSSGGVPSAGRKPLPSATDPGTGQRIGLDHFNFLAVLGKGNFGKVMLAETKRSKRLYAIKVLKKEFIIENDEVESIRSEKRVFLIANRERHPFLTNLHACFQTETRVYFVMEYISGGDLMLHIQRGQFGTKRAQFYAAEVCLALKYFHENGVIYRDLKLDNILLTLDGHIKIADYGLCKEDMWFGSNTSTFCGTPEFMAPEILLDKKYGRAVDWWAFGVLIYQMLLQQSPFRGEDEDEIYDAILADEPLYPIHMPRDSVSILQKLLTREPDQRLGSGPTDAQEIMNQPFFRNINWDDIYHKRVAPPFLPQIKSATDTSNFDSEFTSVTPVLTPVQSVLSQAMQEEFRGFSYTADFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QV90</accession>
    <name>E3QV90_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Leucine rich repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09922</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697384">
        <property type="protein sequence ID" value="EFQ34778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098798.1">
        <property type="nucleotide sequence ID" value="XM_008100607.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QV90"/>
    <dbReference type="GeneID" id="24415287"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09922"/>
    <dbReference type="eggNOG" id="ENOG502S6PB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021422_1_0_1"/>
    <dbReference type="OrthoDB" id="5213490at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="598"/>
            <end position="634"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="798" mass="88563" checksum="50A4A81CB703C152" modified="2011-01-11" version="1">MAALPSYQDAVSRLDWLQLVTSYVADKDLASLCSVNRRFYLLFAPRLWNDPLVAVRRLGLHPSDDLEWYLSFVFDHMQLVRQSTLALITTLDFRDFAKDNAHFSSDNSPRTIPETLRRLPGILPNLRCILLDGHVDADPAFLAATPPPDPTTPSGSSHGVLALSLAHCQTQLPNGFFYSDRVQHLVYLDVSGLPGSLQPLVAAVNGRRNLGRLKILKARRRELNDATALSLFEAFKSSLWSLDIAENNITDSALDRFVTHCFNSPSLRSQSRFATEGRLVFDGHGNGTYGQFMSIQESDWSGTFSHPERHFVDAPAYRADANRVLQEDEAVRTNGRTPLRRDSVDYVKAAIAGGMDQPAPDWSDMPYLDVCTAPVGITHLHLSDNRGLTSSGLERLIRTSQGQLEELSCDSLLFQPVHRSAAQQHLPWPSDMKLRGALGCAYVFRPVLSSNLRVLRIHHSLVTQIPTLETDGLSTMARLWLAETSIRERSEMAFPAAFEPDTNPRLTSLTLTNIPRRSSGPLIDKILHFMSLAGLQEYAIHAMTHSSSRRGPVPLRGLRHIRLEFEADPIEDPTGFSTVEDLDAQELLKLDEGEGFSFFAGERPQPRTSAETATKKKATESGGHPAGPHKVTTSRLAGSLCGDMDGEYMSYGDTWGQQQIDRKVWVGSGVPSTSPAVNEYTRLVMHPPLRSRVGPASLAHVRAGVPAGALLFHAAWDAIVMPPELRPPRRTELHGMRDVLEAVKRFRAETRAGCEAARGAAVEGMAEPTRPRHFFWTGRLEVSAQQSMAHYRAPSYWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWL4</accession>
    <name>E3QWL4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Endoplasmic reticulum-Golgi intermediate compartment protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_10396</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Plays a role in transport between endoplasmic reticulum and Golgi.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Endoplasmic reticulum membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Endoplasmic reticulum-Golgi intermediate compartment membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Golgi apparatus membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ERGIC family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697390">
        <property type="protein sequence ID" value="EFQ35252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099272.1">
        <property type="nucleotide sequence ID" value="XM_008101081.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWL4"/>
    <dbReference type="STRING" id="645133.E3QWL4"/>
    <dbReference type="GeneID" id="24415761"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10396"/>
    <dbReference type="eggNOG" id="KOG2667">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034705_1_0_1"/>
    <dbReference type="OrthoDB" id="270930at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033116">
        <property type="term" value="C:endoplasmic reticulum-Golgi intermediate compartment membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061852">
        <property type="term" value="C:retrograde transporter complex, Golgi to ER"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045888">
        <property type="entry name" value="Erv"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012936">
        <property type="entry name" value="Erv_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039542">
        <property type="entry name" value="Erv_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984">
        <property type="entry name" value="ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984:SF25">
        <property type="entry name" value="ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07970">
        <property type="entry name" value="COPIIcoated_ERV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13850">
        <property type="entry name" value="ERGIC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="400"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="Endoplasmic reticulum vesicle transporter N-terminal" evidence="8">
        <location>
            <begin position="8"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="Endoplasmic reticulum vesicle transporter C-terminal" evidence="7">
        <location>
            <begin position="143"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU369013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ35252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="437" mass="48891" checksum="014C63349A23E249" modified="2011-01-11" version="1">MPAKSRFTRLDAFTKTVDEARIRTTSGGIVTIVSLIVVFWLAWGEWADYRRIEIHSELIVDKGRGERMEIHLNMTFPKMPCELLTLDVMDVSGEQQHGVMHGVNKVRLRPRKEGGGVIDIKALDLHSRDDSAEHLDPNYCGPCYGAQAPPNAQKPGCCNTCDEVREAYAQASWAFGKGEGVEQCTREHYAERLEEQRQEGCRIEGNLRVNRVVGNFHLAPGRSFSNGNMHVHDLKNYWDTPADAQHDFTHTIHSLRFGPQLPDQVTKKMGKRAYAWTNHHGNPLDNTHQDTNDPNYNFMYFVKIVPTSYLALNWQKSTAYQDDDSSSLGLLGQGNDGSVETHQYSVTSHKRSLAGGDDAAEGHQERLHSRGGIPGVFFSYDISPMKVINREERAKTFTGFLTGLCAIIGGTLTVAAAVDRGVFEGGMRLKKMRSKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QY15</accession>
    <name>E3QY15_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10908</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697399">
        <property type="protein sequence ID" value="EFQ35753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099773.1">
        <property type="nucleotide sequence ID" value="XM_008101582.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QY15"/>
    <dbReference type="STRING" id="645133.E3QY15"/>
    <dbReference type="GeneID" id="24416273"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10908"/>
    <dbReference type="eggNOG" id="ENOG502SH7T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018104_0_0_1"/>
    <dbReference type="OrthoDB" id="39175at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="430" mass="48572" checksum="98E06440CCD6422F" modified="2011-01-11" version="1">MAPSPSDDGSVSVANAPSRIVARQACDGCRSRKRRCTFKGDDAIHWANAGQASDVATSLRDIDYWDTVSHQKWASSYLLALTFHQTGNTNLWRMLEVESMQLLRLLEVQNSSSYIGLDAIETQLRKKAFWLMFYAYIHHTHSYRHERVTFLDPVILQEINLEELMPVPVDDEFISCAGILPCPEDISAKSMTAGFNIHSRIFSAARLQSPLCSCPQARDPTIRLARLKEQLCHLKYMLDTVQPAYKPWKKSKSALTPASDDDSVRIIQRDIIRANIQTTHLWLQIVLLGQIDNIISEQSVSASPPKDPAPHVAFGFLPPPFSQRQGQDAVCDERENICRELLHTVHSFSRSALEPNGNGLVYKLRDIAVALLPFSYEVHEERSLRVREYLAELSELLSILDVSEIVNTLSLQSWVDTSRNRTTDSPSTKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QY57</accession>
    <name>E3QY57_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Aminopeptidase I zinc metalloprotease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_10990</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M18 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697400">
        <property type="protein sequence ID" value="EFQ35795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099815.1">
        <property type="nucleotide sequence ID" value="XM_008101624.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QY57"/>
    <dbReference type="STRING" id="645133.E3QY57"/>
    <dbReference type="GeneID" id="24416355"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10990"/>
    <dbReference type="eggNOG" id="KOG2596">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019532_3_0_1"/>
    <dbReference type="OrthoDB" id="9880441at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05658">
        <property type="entry name" value="M18_DAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.250.10:FF:000001">
        <property type="entry name" value="Aspartyl aminopeptidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.250.10">
        <property type="entry name" value="Aminopeptidase i, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001948">
        <property type="entry name" value="Peptidase_M18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023358">
        <property type="entry name" value="Peptidase_M18_dom2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28570">
        <property type="entry name" value="ASPARTYL AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28570:SF4">
        <property type="entry name" value="VACUOLAR AMINOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02127">
        <property type="entry name" value="Peptidase_M18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00932">
        <property type="entry name" value="AMINO1PTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101821">
        <property type="entry name" value="Aminopeptidase/glucanase lid domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4 10" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="52"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ35795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="603" mass="64255" checksum="0036F1CF07684C89" modified="2011-01-11" version="1">MNRFLLTDSNSAVQASHPLDDSPVMTKHTPESLRNRVSSLSLRLQAMEAAEAMSRSQSPAPPSSMSASTTLPSSARSAAPASKPFLLADMDGRPPAENPVCEACWNSLRYSEVRQTTRAAHPSACRLCAVAAGKPEAYTKPFVDFLAENPTIFHTVDHFKDKLAAAGFTELPSRDSWADKLKPGGKYWTTRNGSALIAFTVGKAYKPGNGVAMIAGHIDALTARLKPVSSKPTRAGYLQLGVAPYAGALNQTWWDRDLAIGGRVVVRDESSNKTTTRLVRLDWPIARIPTLAPHFGVGMMGQNNPETQAVPIIGLDSPSDDSSAAAAPVEPLGPKGAFVNSQPPKLVKLISSQLGLSSPTQIINWELELYDSQPAQTGGLDREFIFGGRIDDKLCSWAALTALLAAESDPDDGVIKLVALFDDEEIGSLLRQGARGNFLPLTIERAVESLSGAAGIAFGTDVLCRTFAASFLLSADVTHAGNPNFLGYYLDEHVPRLNVGVTICGDSNGHMTTDAVSTAILQRVGELSGAPTQTFQIRNDTRSGGTVGPMLSAAMGVRAADAGLPQLSMHSIRATTGALDPGLGVKFFKGFLDHWEKVDAEWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYQ6</accession>
    <name>E3QYQ6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_11138</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697406">
        <property type="protein sequence ID" value="EFQ35994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100014.1">
        <property type="nucleotide sequence ID" value="XM_008101823.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYQ6"/>
    <dbReference type="STRING" id="645133.E3QYQ6"/>
    <dbReference type="GeneID" id="24416503"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11138"/>
    <dbReference type="eggNOG" id="KOG0684">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018012_2_0_1"/>
    <dbReference type="OrthoDB" id="3366823at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008395">
        <property type="term" value="F:steroid hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050529">
        <property type="entry name" value="CYP450_sterol_14alpha_dmase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24304:SF2">
        <property type="entry name" value="24-HYDROXYCHOLESTEROL 7-ALPHA-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24304">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="346"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ35994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="603" mass="68143" checksum="44AB4AF7AB2B34FA" modified="2011-01-11" version="1">MGVLSSICGTPDVNEIIESFNHDLVTWAFKLVVLSVPFLLTYLLTYIRFFVQTWSLKTDELHPSPAPQYLVPGLGHTYSILFNAEKFLRPLQMKVQSHVLSLSTPLSTILYVLPGEGVRSLFRASKDLLPVPGIFDALTVFFGLTPADYHVFNHEHISAFEAKKDKRYSTFHEDPSRRIMELQRHDFITFLHGENLRVVMDEFSLNLGQLFRSHHSHVPPSEPVNLPDLYVFLRDSIFRAEVEALYGKHMFAICPSLCEDFWAFYEAFPVISRGSPRWLYPAQYLSRDKMLHNLDKWRRWCNSSSHQEDEELGNSVSSPIWGTQYVKNMVRRYEGLEFSDAGASSVLLGFLFVTTANSIPAAVWMILHILLDKPLVSRLRQELLKESKAKDAPINYTALLSAPLLNSVYRETLRLHIAGSIGRKAFGEGARLRGGSLSALQSGTTSLSANWLGGLDESVWNIGREIDGRTEYPVESFWAERFLEYPDDPASGPLRKPPSIYTDTIGTGLAKPFRDDSKARLTEPAALRGYFFPFGGGAWRCPGEALAKNTILVTAFLLLKELDVEIIDPVDAAKASSQHRTIPFGTHAFDRKVPIRCWKRSQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYR8</accession>
    <name>E3QYR8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Magnesium-dependent phosphatase-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11150</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697406">
        <property type="protein sequence ID" value="EFQ36006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100026.1">
        <property type="nucleotide sequence ID" value="XM_008101835.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYR8"/>
    <dbReference type="STRING" id="645133.E3QYR8"/>
    <dbReference type="GeneID" id="24416515"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11150"/>
    <dbReference type="eggNOG" id="KOG4549">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071162_0_0_1"/>
    <dbReference type="OrthoDB" id="2865258at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07501">
        <property type="entry name" value="HAD_MDP-1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000155">
        <property type="entry name" value="Putative magnesium dependent phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010033">
        <property type="entry name" value="HAD_SF_ppase_IIIC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035679">
        <property type="entry name" value="MDP-1_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010036">
        <property type="entry name" value="MDP_1_eu_arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01681">
        <property type="entry name" value="HAD-SF-IIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01685">
        <property type="entry name" value="MDP-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17901:SF14">
        <property type="entry name" value="MAGNESIUM-DEPENDENT PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17901">
        <property type="entry name" value="MAGNESIUM-DEPENDENT PHOSPHATASE 1 MDP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12689">
        <property type="entry name" value="Acid_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01131">
        <property type="entry name" value="C1.5.2:_MDP_Like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="224" mass="24459" checksum="9E3679E3EDA19C21" modified="2011-01-11" version="1">MPKKLSKNPHGSSTPSTSTTSSSVAALSLPRILTDGLPVPALVVFDLDYTLWPFWVDTHVAPPLKANAAHAAVADRHGESFAFYPDVPRVLYTLPLAGVRVAVASRTSAPDLARDMLKLLHVPPPGADEFAAAAAAGKKDKAKRALDCFDGPLEIYPGSKIKHFETIARKTGVAYTDMLFFDDESRNRETESLGVTMHLVRDGVTWAEMEKGVMEWRKRRGYLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZ79</accession>
    <name>E3QZ79_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_11331</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697412">
        <property type="protein sequence ID" value="EFQ36167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100187.1">
        <property type="nucleotide sequence ID" value="XM_008101996.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZ79"/>
    <dbReference type="STRING" id="645133.E3QZ79"/>
    <dbReference type="GeneID" id="24416695"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11331"/>
    <dbReference type="eggNOG" id="ENOG502RP1A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1219620_0_0_1"/>
    <dbReference type="OrthoDB" id="4811426at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ36167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="227" mass="25247" checksum="7FE992258C83CDF1" modified="2011-01-11" version="1">MWGWPGSRVGGLWYTPLVSSSPVTANLSNTTLIYALLYGYYSSLKVSSLWEELKKADGALRKNLLQVDKLAAVQLLREFFCRTADGKFLSYLIIRYANTYTNLLGRDLDICYLNLVLNLPGLLQAVYDAKAADKPILTLATELSKAISLGSKVPAPRAYLYAFTKLNRSLKIKTKILISTYNLASTGLDDLKVANYLVYYSVNKHATKVSQASGRINRQGQPLTCFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZE1</accession>
    <name>E3QZE1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11374</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697415">
        <property type="protein sequence ID" value="EFQ36229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100249.1">
        <property type="nucleotide sequence ID" value="XM_008102058.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZE1"/>
    <dbReference type="GeneID" id="24416738"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11374"/>
    <dbReference type="HOGENOM" id="CLU_2426893_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="91" mass="9785" checksum="CD6D6EB76358C9B5" modified="2011-01-11" version="1">MIPRASTVLPIIVTQPAGFHHQTTGRGGIAKGSESLMFWKTVRKGRGYRPNAKSIDGKEFDADGSDILPPNTTPNTAEPARRFRGAAPSSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZM1</accession>
    <name>E3QZM1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sulfate permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_11454</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697418">
        <property type="protein sequence ID" value="EFQ36309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100329.1">
        <property type="nucleotide sequence ID" value="XM_008102138.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZM1"/>
    <dbReference type="STRING" id="645133.E3QZM1"/>
    <dbReference type="GeneID" id="24416818"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11454"/>
    <dbReference type="eggNOG" id="KOG0236">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003182_8_1_1"/>
    <dbReference type="OrthoDB" id="288203at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008271">
        <property type="term" value="F:secondary active sulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07042">
        <property type="entry name" value="STAS_SulP_like_sulfate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.750.24:FF:000024">
        <property type="entry name" value="Sulfate permease 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018045">
        <property type="entry name" value="S04_transporter_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00815">
        <property type="entry name" value="sulP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="SULFATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SpoIIaa-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01130">
        <property type="entry name" value="SLC26A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="194"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="280"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="408"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="466"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="489"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="7">
        <location>
            <begin position="567"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="715"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="788"/>
            <end position="807"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ36309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="807" mass="88176" checksum="34312A4860FD62DB" modified="2011-01-11" version="1">MPSTVGRSLAKGLGIDVDARYRNEPTEAVQSAAASFRSVEQYEEEEPTVAEFLYAHRPTVHGAVAYIKSLFPFWSWIFHYNATWLLGDVIAGVTVGFVVIPQGMAYAILAKLPPEYGLYTSFVGFILYWAFATSKDITIGTVAVMSQLVGNIILRVQDTHPQYSGPQISQALAVIAGAVLLFIGLVRLGWVVEFIPLVAITSFMTGAAISIAAGQVPALLGLQGVVTRNPTYQVIIDSLKALPTARLDAAMGLTALFLLYAIRSFCNFMSNRQPHRKKFWFFMSTLRMAFVILLYVLVSWLVNRHVNWSAKKARFKILGIVPSGFRHTGAPKIDTGLLSAIAPDLPVTIIVLIIEHIAISKSFGRINNYVINPSQELVAVGFTNLFGPFLGAYPATGSFSRTAIKAKAGVRTPLAGIFTAVIVLLALYALTAVFFYIPMASLAALIIHAVGDLITPPRVVYQFWEVSPLEVFIFFAGVFLTIFTNIENGIYLTMCASAALLLVRLAKAKGHFLGRVRVYRATKDTAGKGVPFNEKGESVDVPSREAYIPLAKDDGSNPHIDVETPYPGVFVYRFGEGFNYTNQAHYMDRLVEYIQKNARRTILDRYEKLGDRPWNDPGPRRGAKIDMDDQRPIVRAVILDCSAVNNIDVTSVQGLIDVRNQLDHYAEPEVVEWHFANVNNRWTRRALAAAGFGFPSVKDEGNFGRWKPIYSFAPVDSGSDHAPPQMAAQRSRGDEEDAIAPTKGGGGGNDGAAQVAGRGDGKLASVQGMNRPFFHIDVAAAVESAILNAESKSEGRESPANSVLKSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZT7</accession>
    <name>E3QZT7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_11520</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIP5 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697421">
        <property type="protein sequence ID" value="EFQ36375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100395.1">
        <property type="nucleotide sequence ID" value="XM_008102204.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZT7"/>
    <dbReference type="STRING" id="645133.E3QZT7"/>
    <dbReference type="GeneID" id="24416884"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11520"/>
    <dbReference type="eggNOG" id="KOG2789">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009068_1_0_1"/>
    <dbReference type="OrthoDB" id="21471at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd24139">
        <property type="entry name" value="SIP5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039301">
        <property type="entry name" value="Sip5/DA2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31315">
        <property type="entry name" value="PROTEIN SIP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31315:SF1">
        <property type="entry name" value="PROTEIN SIP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="301"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="161"/>
            <end position="263"/>
        </location>
    </feature>
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            <begin position="320"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
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    <feature type="region of interest" description="Disordered" evidence="2">
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            <begin position="461"/>
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        </location>
    </feature>
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            <begin position="547"/>
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    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="759"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="18"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="54"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="67"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="175"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="208"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="220"/>
            <end position="231"/>
        </location>
    </feature>
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        <location>
            <begin position="237"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
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    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="476"/>
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        <location>
            <begin position="490"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="547"/>
            <end position="578"/>
        </location>
    </feature>
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        <location>
            <begin position="617"/>
            <end position="631"/>
        </location>
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        <location>
            <begin position="636"/>
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        </location>
    </feature>
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        <location>
            <begin position="734"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="859"/>
            <end position="877"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ36375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="877" mass="95003" checksum="0DCE208B791DDB48" modified="2011-01-11" version="1">MGNSSTKESRPVDPATDYRQSQTAYLGTSTSRDPPADRFSSRRQSRFSRGDLNLLGLGATGSSSAASRDDVPYERRETRQEREARRLERERVAREKERERSMKEEHVDGGYLVTLGTYTGPEDFSKPIIERRLAPFWRGLNDYSDNWTEYQLICAGRGLPIPAADEQPPPEFIPQANSPASPDDPSQNLAGLTVPMGPRSLSVGSDRSGSLPGSGISSPNAAQQQQRSSSPFKPRAKALAAALSGASRNNSSGDAAPREIRLPNDPYVNGQPLEVFLYKDACECPICFLTYPPYLNRTRCCDQPICSECFVQIKRADPHYPEHHGEPNEQPPNPANPEEASEMLISEPAQCPYCQQTEFGVTYDAPPFRRGLSYAIGYPSQNTAMSSQSSLSSTLSPTSPNSFNRRRAQSLSANAPNVVTTDRVRPDWSTKLAAQRAHQARRAAAATALHTAAFLMGNNEQQRGFTFTRPGRFSRRNTGSRTSSGPSNHPAEESPNRHPESEAVQAGPEPGPRGSSGRGALNNRRSRMEELEDMMFMEAVRLSLAAEEERKRKQEKAERKEAKKRGKEERKAVKKQDRQSFYGGEQSSASASSLSLGLGRRRGNSTTSNLRVEATLQGAQSTSAGASADTSPIAAPSNTGPTSAPSLAPVPTASSKGKAVERPAVETQSSENSFQSTSSTPSLPIPTPGRGPSHLRHMSNASSISSSLADSAAGSYTNQVYLDPRASELSVGNRSEEGDRDNTEPMFNFRSLAEMVGVDIENGETNENEGGASGEGQRATTRKKDEVEDEPEAEHMEETSIEPPTHASVGILKLPPTVPEEPVDGRSSKGDVSPGSGALTPEVTITPETPGLATEEDTEMKRLGHDNVVERSSEIIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3R008</accession>
    <name>E3R008_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">NADH-cytochrome b5 reductase</fullName>
            <ecNumber evidence="10">1.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_11597</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>2 Fe(III)-[cytochrome b5] + NADH = 2 Fe(II)-[cytochrome b5] + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46680"/>
            <dbReference type="Rhea" id="RHEA-COMP:10438"/>
            <dbReference type="Rhea" id="RHEA-COMP:10439"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9 10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion outer membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.6.2.2" evidence="10"/>
    <dbReference type="EMBL" id="GG697425">
        <property type="protein sequence ID" value="EFQ36452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100472.1">
        <property type="nucleotide sequence ID" value="XM_008102281.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R008"/>
    <dbReference type="STRING" id="645133.E3R008"/>
    <dbReference type="GeneID" id="24416961"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11597"/>
    <dbReference type="eggNOG" id="KOG0534">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003827_9_1_1"/>
    <dbReference type="OrthoDB" id="432685at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090524">
        <property type="term" value="F:cytochrome-b5 reductase activity, acting on NADH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06183">
        <property type="entry name" value="cyt_b5_reduct_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000009">
        <property type="entry name" value="NADH-cytochrome b5 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001834">
        <property type="entry name" value="CBR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370:SF101">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00406">
        <property type="entry name" value="CYTB5RDTASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9 10" id="KW-0274">FAD</keyword>
    <keyword evidence="4 9 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0520">NAD</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="11">
        <location>
            <begin position="52"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601834-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ36452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="296" mass="32155" checksum="549B8708D4FA9C3D" modified="2011-01-11" version="1">MTSRAAIRRFRPANVVAAVAAGGIGLGVMSKLLVGNASAESGAPPNVFGAGPAFVSLPLESSEKVNHNTKRLRFKLPQRDAVSGLSLTSAVLTMSWPEGRWFPVARPYTPIQPLDDAGYLELMVKKYPDGKQSTHLHSLTPGETLLFALAIKGHQWKPNSYSHVTMIAGGAGITPIYQLSQGILRNPQDKTAVTLIFGINSDQDVLLKEEFEQFEKEFPGRFKAIYTVSNPMPNSPFRKGYVTKELLQEVGAVPKGIETKVFVCGPPAMEAALVGKRSAPGVLQQVGYRKDQIHKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3R011</accession>
    <name>E3R011_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Necrosis inducing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_11600</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Necrosis inducing protein (NPP1) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697425">
        <property type="protein sequence ID" value="EFQ36455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100475.1">
        <property type="nucleotide sequence ID" value="XM_008102284.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R011"/>
    <dbReference type="STRING" id="645133.E3R011"/>
    <dbReference type="GeneID" id="24416964"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11600"/>
    <dbReference type="eggNOG" id="ENOG502QRV1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062263_1_0_1"/>
    <dbReference type="OrthoDB" id="89086at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008701">
        <property type="entry name" value="NPP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33657">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33657:SF8">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05630">
        <property type="entry name" value="NPP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029958">
        <property type="entry name" value="Necrosis-inducing_protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003181115" evidence="3">
        <location>
            <begin position="19"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ36455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="244" mass="26627" checksum="419216531C95BCDE" modified="2011-01-11" version="1">MFVGKLLPFIGLLRAASGTPVDRLLDRRDVVGHDTLNPLPQRVQDNYSGAAIARFNPLLHIASGCQPYTAVDDAGNISGGLKPSGKSDGGCRDTSKGQTYARIGQYNQRWAIMYAWYWPKDQPLDGVSTGAHRHDWENVVIFINDPSDANPTILGGGASGHGQYKESDFLPRQGDSVKVEYFAEFPTNHELQFTSTVGRTYPVLDWDVMTPAMQNALNNADFGSADVPFKDANFISSLGNAANF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>E3R080</accession>
    <name>E3R080_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Kinesin motor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_11664</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697432">
        <property type="protein sequence ID" value="EFQ36518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100538.1">
        <property type="nucleotide sequence ID" value="XM_008102347.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R080"/>
    <dbReference type="STRING" id="645133.E3R080"/>
    <dbReference type="GeneID" id="24417028"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11664"/>
    <dbReference type="eggNOG" id="KOG0247">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004757_1_0_1"/>
    <dbReference type="OrthoDB" id="123929at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005871">
        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000091">
        <property type="entry name" value="Kinesin family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24115:SF1008">
        <property type="entry name" value="KINESIN-LIKE PROTEIN SUBITO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24115">
        <property type="entry name" value="KINESIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0493">Microtubule</keyword>
    <keyword evidence="4 5" id="KW-0505">Motor protein</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="8">
        <location>
            <begin position="12"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="269"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="557"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="739"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="605"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="269"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="557"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="749"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="776"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="800"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="107"/>
            <end position="114"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ36518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="810" mass="89193" checksum="DC4D658DAC748CEC" modified="2011-01-11" version="1">MDSSSSQKSANLFQVYLRLRPPPAGAAQSDRFLDVEECDEDSHPTHITMNPPNDRKRSTEKFAFTRVFEEDATQLDVFHCIGVASLVEGVLAPHGGQGTDALIATLGVTGSGKSHTILGSRSTRGMTQLALDVVFRSIGTNLYDSPDLEGSLQASDFSDAIIISAPYFLETVFADFGSSRGGGSRAGTPMLVGDPVSLLRTPFLRLGRHEKPHLPPSMSVFGDVRLVPPTPDSPRRKQRDALSTLMLEEHLEHQGDAQRQFMTMTVASKTKDVAKTSTKGEHYPPPTPRRNLQRPSALPCSPDISSVNVSSDPDCDYAVVLSMYEVYNDKIYDLLTPPIKSNATKEYRRRPLLFKSTEYSADRKVVAGLKKIVCTNMREAIMVLEAGLHERQVAGTGSNSVSSRSHGFFCVEVKKRAKVGRGRAWVGNTLTVVDLAGSERARDAKTQGATLAEAGKINESLMYLGQCLQAQSGMGSSNKPTVMPFRQCKMTELLFSNSFSATSSAGVVPRRNAQRAVMIVTADAQGDVNATSQILRYSALAREVTIPRIPSITSTLLADTPTTSHPSAGIRSPDLPQHRRGYFGHGSAGHRSFSPGSDNEDRVLMEHAALEIARMQEEITNLHIELDNEREARISAEAHLLSMEDRLLDVEQTVREDCMAEFDARFEMELARWKATLAAEQEKGEEHWDRKMELFEKGLGVTLAEDDNAGDDKENLLIEDLEDENERLRRENEVLKRELAARSPTKRKPLQERADFSGRKAGTGVSNLGQKMEQLRVSNESTAGTSNSGSPKKMRKLATKRCETVNDHDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0C6</accession>
    <name>E3R0C6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ankyrin repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11723</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697439">
        <property type="protein sequence ID" value="EFQ36564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100584.1">
        <property type="nucleotide sequence ID" value="XM_008102393.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0C6"/>
    <dbReference type="STRING" id="645133.E3R0C6"/>
    <dbReference type="GeneID" id="24417087"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11723"/>
    <dbReference type="eggNOG" id="ENOG502SPEM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102598_0_0_1"/>
    <dbReference type="OrthoDB" id="4812218at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="186" mass="21046" checksum="AAE79581DCE78D9F" modified="2011-01-11" version="1">MLINPFRPCEGSPTFQEEYRTNYKPKFINSWVGPQIVAPDTPYVAAVGQKQLYFLDTRFDPKTAQHIKEQIERATVAGGPYEATKIDEISATAEVINTQTNETLFVFDPPYARVLFAKGINRRNPALQLPEHEPSGDWLVTYDVGNLLKNGIGYCNPLCKQAVDAPKEDGEDDASYHKRMDDLHRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0R0</accession>
    <name>E3R0R0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_11846</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="GG697472">
        <property type="protein sequence ID" value="EFQ36698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100718.1">
        <property type="nucleotide sequence ID" value="XM_008102527.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0R0"/>
    <dbReference type="STRING" id="645133.E3R0R0"/>
    <dbReference type="GeneID" id="24417209"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11846"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_25_2_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF223">
        <property type="entry name" value="CYTOCHROME P450-DIT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="4">
        <location>
            <position position="517"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ36698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="585" mass="66828" checksum="9A462ED697F0749C" modified="2011-01-11" version="1">MNIIVPQHIYFLVGLLCFAFLFLAFALYSWSLLRNYQAAKHLQIPIIITPVSWQQPLWMLLGETVGRPIQRLPLCRWSLYSRFGWQMYDKYRLHANLGPVFVIVSPADNEVVVSDPEVATRILHKWRQFPKSAIQTKVFEIFGPNVGTIWDDDWARHRKMVSVGFKESNYGLVWETTRRQTDKLVESWAKAGRQQKLASLEEITDAVSALALHVLVVAGFGKKEDNDNDNGNNDKDHTYLTTAPGHKLSYIDCLKAILRNMIATSLLQSFTISDILLPKSLRLLKQANREFRAYMAERVEVERRDIAMRKTTSQSNLLSSLVSANEVSRSQGNSAIAKNKLFLSDSELRGNFFTFNLAGYETTSGVLSYAIPWLAVREDVQAWVYEETCAVLNGSLSYAESFPKLTRCLAVLVSRLKERSTQKRTELTKNLTQPRYTNEESRVLTIRGAEIPVPKHTYVTISCTTLMTDPVLWGADSLEYNPFRWIRTAETDKGPREQIMEPPEGTFIPWSHGPRVCQGKKWSQVEFVAVIAFLVRNNRIEVARRNGESKLDAALRLKNILEDSYMNITPKIRCPREGGIICKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0V3</accession>
    <name>E3R0V3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11887</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697500">
        <property type="protein sequence ID" value="EFQ36741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100761.1">
        <property type="nucleotide sequence ID" value="XM_008102570.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0V3"/>
    <dbReference type="GeneID" id="24417250"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11887"/>
    <dbReference type="eggNOG" id="ENOG502SUV8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_642516_0_0_1"/>
    <dbReference type="OrthoDB" id="5174889at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="340"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="397" mass="44611" checksum="C7A666F810765B87" modified="2011-01-11" version="1">MDDKAAVAAALQKRDVESLGKPRYEKVYLVFTGAADRNKIAEGMSQYLQRAEKHNPALPADWRKRTEWFQTQTNVMGKAVAHERWYKDLSPGRNLPVATGKTLLASIAKTASQKPSIDIFQLAPCRDTDVWDFINMLPNINVYHLFYGYNSRQGSAYEGMKPAESLALAERQANFHATLQQHLQTKHPIARLIFTQNVPTFSNPGAGSQSLAWCKRYFPETDIKMSLRDPFWTSLIKEANPYAAKEVQLKNIPADEDEFLNLVVNARLDDNNFRKSVHAMLESAARSETFKEHSQRSHYRVANILVGEFAGEPAPTLELGDANHITAVLEYLDTEMRGARGRSAGKLQPASCDKSGKDPRQPPNVIIGTRPSNSGWVLTGCDVTQTRNNIERLLQQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0V6</accession>
    <name>E3R0V6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Beta-ketoacyl synthase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_11890</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697502">
        <property type="protein sequence ID" value="EFQ36744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100764.1">
        <property type="nucleotide sequence ID" value="XM_008102573.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3R0V6"/>
    <dbReference type="GeneID" id="24417253"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11890"/>
    <dbReference type="eggNOG" id="KOG1202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_37_7_1"/>
    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009403">
        <property type="term" value="P:toxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19532">
        <property type="entry name" value="C_PKS-NRPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000019">
        <property type="entry name" value="Polyketide synthase type I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049552">
        <property type="entry name" value="PKS_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF20">
        <property type="entry name" value="HYBRID PKS-NRPS SYNTHETASE APDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22621">
        <property type="entry name" value="CurL-like_PKS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21089">
        <property type="entry name" value="PKS_DH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="10">
        <location>
            <begin position="4"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="11">
        <location>
            <begin position="956"/>
            <end position="1263"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="9">
        <location>
            <begin position="2453"/>
            <end position="2531"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="8">
        <location>
            <begin position="956"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="8">
        <location>
            <begin position="1107"/>
            <end position="1263"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="8">
        <location>
            <position position="988"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="8">
        <location>
            <position position="1169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ36744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="3070" mass="338562" checksum="0BEEE36C59A72A22" modified="2011-01-11" version="1">MYDSEPIAIIGSACRFPGGVDSPSKFWEFLLQPGDLRSEVPKQRFSAEKFFNSNGMHHGSTNSRYGYFLKEPLGGFDAPFFNIHAGEAKSMDPQQGLLLETTYDALSSAGLVQDLQGSDTAVYVGLMTHDFETIKTQDMHHMPTYFATGVAASIASNRLSYVFDWHGPSMTIDTACSSSLVAVHHAVQQLRSGQSRVAVAAGVNMIMSPLSYVSESKLSMLSPTGRSRMWDAAADGYARGEGVAAVVLKTLQQALSDGDHIESIIRETGVNQDGKTTGITMPSHLAQEALIQDTYARAGLDLSRIGDRPQFFEAHGTGTPAGDPQEAEAINKAFFGDKVLDTLQPQDLLVGSVKTVIGHSEGTAGLAGVLKASLAVQHGAIPPNRHFEMLSPAVQPFYRHVCIPTKTQPWPQVAPGYPRRASVNSFGFGGTNAHCIIEEYVGSGTRQSLSQKSISCDVENQPSSTTYGMPLVLSAKSQRSLKDYMHAMLQFLKSNPAIDMADLAWTLLRKQAVLPVRHAISCHTRDGVCLALEAAINDNLGRDFSFNRGNKDQPQILGVFTGQGVQWSGMCKSLLASIPWTRDIIDELDASLQALPAQYRPLWKLRQLLSGEGDWTNAAEARFSQPLCAAVQLVLIRLLQAAGVRFAAIVGHSSGEIACAAAAGYITPFQAIRIAYLRGLAVATPHAGSHSPTEGAMLAADITHEDAKEICSLEDFEGRICVAAYNSPTSVTLSGDAEALRHAESVLKDEGKFTRFLRVDKAYHSHHMAPFADTYVKALTDCDCAANAASNALGSRPLVSWYSSVNPGRLLKCTDVTAEYWKANLVSPVFFSQAVERVARDYNIACAVEVGAHPALKRPTVATIHTISGTELPYTGCMKRDQDDTDAFAEAMAYLWERFASFKILDADSFMKAVSPSANPRKSLAKAIPRYSWDHTRTYLTETRAEKAFLAGPAPHPLLGSILPTTTDSTFQWQSFIKPEDDKWFEGHHLQTQLVVPASGYAVMVMEAALYVARKRLGQDVDVTVLEVLDLSIDKAMTFDEKNSMAELLVTLKVIHQDSEQLSVDVNIDSALERETKPSMTARGRVVVTLGSPLTSSPQRGLNEPLHPNEIDINRFYEEIERLGIAYTKKYHGIHELRRADCRAAGRLLHYRFPNNPSQEIVIHPATLDTAFQAVMGAYSYPGDRALKSTVIPVHIDRIALFPGACASALGSRDEVSVLFNATCSSLEDSVPDGDVEVFDDSSAVLFQVDNIALHPLHRPEPSADHLMFTKTVWGPYSPDRILDRPEFRATDEDRRMIPVIERIVYHYVKDFLKKLTVEDRRKASPSLQKYIHWNEQVLGKAREWKSTFYEPDWEMDTAADIEKLCEQNWYHPYVRLIKRVSENVMSTIRNNTNPFHWMNEDGLLGEFYASPLSNGPCWNNGQHLVNQLCHRFPNMNILEIGGGTGSATRYILDIPELGFNSYTFTDISPTFFDKAREAFHQHKDRMDFRKLDITQDPASFTPHSYDLVVASSVLHATPRLVETMTNVRSLLKPGGHVIVVEATFKEYLRTSYIFGLFPDWWAGYEDGRILDPFVSYDEWDSILKRAGFSGIESRTSDHESWVFQNSLFSARAMDPKMERLESPPLTVSSQHDDGANLPKLIFVGGCSDRSSALVGKLQDKLAYRRSLHLKRLEDVVKQAAHLGPGSTFVVVSELDDEMFEDIDSIKLEAAKWLLTGGYAKIVIWVTAAAFTRNPRQAMTIGLLRTIYLENPEIYVQNIDLDNVEHFNYAPVIVEHLLQLEYISTLPKDSSSLVRNHEPEVYLVDGRAWIPRIKHDIARNNRLNSARRVILVDIQPEETPVRLSLAPDGETSFLELTDTMVGPFPPSAPSSFSSVHGCLVQVRVHFALTGAIRVGNLGFLHLCQGFSTETKTPALVLADSNASVVCVPASRVFNLPSGDNCILLHVVASLISQEIMNSAVPGTSVLLFETPDFCVDAIAKQAKEKNVQVYNVSSQKLAGLDHNSGSTWMHLDPWVSDIALQKMVTVGASVYCDFSPATDLKAATLGRRIARNQPPHCVKYGYAHFFAKRGSGTPYGDAHCRDFTMAVEKALRASSGTAHDHIAEAAFIKVAAIQDNKALKDLTTVVDWRPDGKVQARLRPVDSGNLLAPDKTYLLAGLAKTMGRSLARWIITHGGRYVVLSSRHPEVPDRKWIEEMEELGGHVTILSMDLSDEKAVDVGLSMIREALPPIGGIAYGPLVLRDTIFQNMSLEDMNSVLNSKVIGARLLHDRFCDATPGAQLDFFVMFSSAASVGGNPGQSNYNAANAYLQALAQHRRTKGLTASTIHLGAVMGVGYLTRSHLEEQLLKFSDWGKLSEGEFHRLFAEAIVSGQQALRQDEGKVTRLSVTDMSDTEVMTGFPVFEAKYKDSIKLWHNPRFGHLRTPENKSSHEDQGSSARRVSIKDRLREAATMNEAKEAIIDGLAQKTRDILLIPRDQSVNPSVPLLDQGIDSLGAFAVSAWFSQELLVDIPILLVLGGASLEDVAEAAVKRLGRDAIPLIASELEGYQSPTLNSEDSPSASDKSLVSSASSSVASYASGKDEASAKISRRYPLSLGQAYSWKLQQQLSHDHTIFHNTIAYLFEGYIDLKRLGTAVDQVLRRHEILRTAFLDDLEPHEGDDLQQVILETQTWGLICKEVANQAAAEEAMKQLHEEAYDLGSGRPFKLVDFYWSSGHRHLLTVAYHRLAGDGATTSLLMSELSASYDGAGLSATVPQFSKIAIRQRADYKQGRLDADIAYWTSQYNNHAVPIMPVLNLPDCQLADRSNSPPVSWSQHKGVFRLSSAVSAEIRETVRQQKVSRMQFFMAVYATLLAQLTNTTSSGEAEAISRDNGDDDASRMITIGVADTNRATMEDMAAMGFFANLLPVRIETGRKGDRSSFSPVDQLDTVKKAMRGAMLHSRVPYGVLLERLPVTPSLQVSAKDWSHAPLFQAVFDYAGGGVESVRIGDAVMTEQGALQATKLISRERTPYDVVLEIWDDTTRDPLVIVKLQSSLYSSKDVTAFYDAFVKLLSTYSTDLRGYGQMSDSGVFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0Y1</accession>
    <name>E3R0Y1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11917</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697517">
        <property type="protein sequence ID" value="EFQ36769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100789.1">
        <property type="nucleotide sequence ID" value="XM_008102598.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0Y1"/>
    <dbReference type="GeneID" id="24417280"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11917"/>
    <dbReference type="eggNOG" id="ENOG502RASJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1151706_0_0_1"/>
    <dbReference type="OrthoDB" id="4834644at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="241" mass="27318" checksum="38971DE4B944186E" modified="2011-01-11" version="1">MAVQSRRPLSNLDSNVSANQPKTKQYSASTLPPRPSLPEHARWAKVLARSPMVSVKEAMIRALVLKRAPTESSISYLDASSIRDARSTYLKESCQAWNSITRSLYNTRLAILQRGQRAHDSYVTAILIALAQHQCRSAPHKSIHRVHVLLSDIDNKSRMTIYTAEIPNSFLDKLAHPRRPPPPFAEFQVHARTVEYEPYATFQQRLSQALIPCGPKRARDPDYDDDDDEHHAQKRRCADNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q308</accession>
    <name>E3Q308_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7907 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00131</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ24987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089007.1">
        <property type="nucleotide sequence ID" value="XM_008090816.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q308"/>
    <dbReference type="STRING" id="645133.E3Q308"/>
    <dbReference type="GeneID" id="24405496"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00131"/>
    <dbReference type="eggNOG" id="ENOG502STWI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081634_0_0_1"/>
    <dbReference type="OrthoDB" id="3515453at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057229">
        <property type="entry name" value="DUF7907"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25484">
        <property type="entry name" value="DUF7907"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180154" description="DUF7907 domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7907" evidence="2">
        <location>
            <begin position="23"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ24987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="184" mass="19700" checksum="BA021D14BBD9171F" modified="2011-01-11" version="1">MKTASVLALLGVTSATAQFTNQTKPFWLKFSPTNDSSVVTYLASCHSGAGQAGLCPETGGSSHTQYFLNETQSDYQGHILGALTWDQPIGNGNPISSGMNLSPQLVSNGAIPIFSPGDSALFTLGFDENEALFIATNADDSRAAPNAPNYSLEAYYRWHVCWTFVGNYFYKSLVWVTAGAPSNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3E4</accession>
    <name>E3Q3E4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00690</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089566.1">
        <property type="nucleotide sequence ID" value="XM_008091375.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3E4"/>
    <dbReference type="GeneID" id="24406055"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00690"/>
    <dbReference type="HOGENOM" id="CLU_3087112_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="52" mass="5771" checksum="C2DCEC734BFDDDF2" modified="2011-01-11" version="1">MAKGKLVVASDRERKSAQSKANQMTDWILPRGASSLPLPQRLGLVEFNHSFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3G9</accession>
    <name>E3Q3G9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glucan endo-1,3-beta-D-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_00715</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;3)-beta-D-glucosidic linkages in (1-&gt;3)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.39"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PGA52 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.39" evidence="3"/>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089591.1">
        <property type="nucleotide sequence ID" value="XM_008091400.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3G9"/>
    <dbReference type="STRING" id="645133.E3Q3G9"/>
    <dbReference type="GeneID" id="24406080"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00715"/>
    <dbReference type="eggNOG" id="ENOG502QSI7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030276_0_0_1"/>
    <dbReference type="OrthoDB" id="118256at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042973">
        <property type="term" value="F:glucan endo-1,3-beta-D-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018805">
        <property type="entry name" value="YJL171C/Tos1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018807">
        <property type="entry name" value="YJL171C/Tos1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31737">
        <property type="entry name" value="PROTEIN TOS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31737:SF2">
        <property type="entry name" value="PROTEIN TOS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10287">
        <property type="entry name" value="YJL171C_Tos1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10290">
        <property type="entry name" value="YJL171C_Tos1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Cell wall protein YJL171C/Tos1 N-terminal" evidence="10">
        <location>
            <begin position="38"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="Cell wall protein YJL171C/Tos1 C-terminal" evidence="9">
        <location>
            <begin position="219"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="105"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="160"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="165"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF10290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ25571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="464" mass="48627" checksum="B669CADF54393DC9" modified="2011-01-11" version="1">MKSSTVVMLASAAVGQAIQQCSGVAKNEGGNWWCGAVDQILYSNVGHPGTYKAVSNMADDGSCSFEDVPFSGPLAPFNEELVPVFRGPMNLKQVAIYNLSPKAKRSPAVSHSHARRHGHHGHQHLHKKHAEHEHNEEKRGDVWVTATIDGIVQSWINTYHGPTPEAAPPAPPAIAPIAPPVAAPSPTPAPSKPAVAAAAIPKPASNSKAAGSSSGTATGDYTRVGYYNADKAVADGIVFLGNYGGQGSGKFDNVFGNSLSYLNSDATGGAASPQVLNPVTLKSNQEFLIASDKSCDDGGCGYSRPGSVAYHGFKGEDSVWLFELNMPLDGTSGFNADMSALWFLNARIPRTAQYNKCSCWPDCGELDILEVLAPGDTKCKSTFHSNVPGGSSDYFDRPTGKPIKVAVVLDGGSGQVSVKVLSDNVDFSTGLSRSQVDSWLSADSFSAASTGGKTNRVSLFALSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3P7</accession>
    <name>E3Q3P7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_00793</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MNN1/MNT family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089669.1">
        <property type="nucleotide sequence ID" value="XM_008091478.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3P7"/>
    <dbReference type="STRING" id="645133.E3Q3P7"/>
    <dbReference type="GeneID" id="24406158"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00793"/>
    <dbReference type="eggNOG" id="ENOG502RZ48">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030430_1_0_1"/>
    <dbReference type="OrthoDB" id="430354at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000033">
        <property type="term" value="F:alpha-1,3-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022751">
        <property type="entry name" value="Alpha_mannosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31392">
        <property type="entry name" value="ALPHA-1,3-MANNOSYLTRANSFERASE MNN1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31392:SF1">
        <property type="entry name" value="ALPHA-1,3-MANNOSYLTRANSFERASE MNN1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11051">
        <property type="entry name" value="Mannosyl_trans3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ25649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="527" mass="58439" checksum="6737B40AFE46224E" modified="2011-01-11" version="1">MSRLLVSPRSGVQSTSVLAAAAIIAITIVYYFRFDGHITPLRSASFGFRPSKAPDPNLEAINATAQYFVDYPVGPPYKKVFGELGERTKVLRSWIEALEEKDGDGKLRVVGAERRFLDDSIERVAASLFPYLQSPPRNVQTRTPLADLRRSFQSAGTPARHPARHPRVGDGAYGNKTAKEYASLNAGIVIPAGHSTLRLACHLVASLTHVHRTTLPIQIAYAGDEDLPQEDRDTIVKAAAVSYNGHVEFLDVLTVFNDTTLQLMEGGCAIKPFAALGSRYEEVILLDADVVLLQPPEKLLQQQAYRRNGALLFHDRLLWKDQFPERNVWYHDTFKHPSGEMQKSLVWTEKYAEEGDSGVVVLNKGRLDVLMGLLHVCWQNTDEVRNAWTYRITYGDKETWWIGLEATGSAYSFSRHYGGVVGWQKKPVEGEEAGRTQVCSLAIAHVNEAGGLLWYNGGLEMSKMGDPPAFEMPTHWMIDQEWVNGGGKKDMSCMIGTGAQELSGHERGVLEQSIKAAKDVDGRLDSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3W5</accession>
    <name>E3Q3W5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">2OG-Fe(II) oxygenase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_00861</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089737.1">
        <property type="nucleotide sequence ID" value="XM_008091546.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3W5"/>
    <dbReference type="STRING" id="645133.E3Q3W5"/>
    <dbReference type="GeneID" id="24406226"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00861"/>
    <dbReference type="eggNOG" id="KOG0143">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010119_6_2_1"/>
    <dbReference type="OrthoDB" id="288590at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044283">
        <property type="term" value="P:small molecule biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="3">
        <location>
            <begin position="166"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ25717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="344" mass="39308" checksum="21D6321773B4B7D1" modified="2011-01-11" version="1">MSEKTKYVEREIPEISLQDFESRVDEITSQFCSAAENIGFFAIKDHGITEAEVDEMFSLSESFFRLSDETKATVPWTPQNVGWEKMSQVRPSTGQPDNKESYQLQFGEHMEGKWMGDENLPGFKSRSLAFMHRVQGVSEKLMLCLARGLGFQDDYFIKYHDASRPDSQSCLRLLHYYETPKVSDGKIYHRAGAHADWGFLTLLFQRGEQSGLEICPGREVVTEHALGDTWTRVEFKPGVIVCNIGDLLMSWSDDRFKSTYHRVKAPCDEAEDYYGERFSMAFFNQPCKDAIIQGPKQKYPVVTGEEFNRNAMNRMYAALQAKMAAGEEPNGQQMKLETPLTKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q468</accession>
    <name>E3Q468_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF202 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00524</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089400.1">
        <property type="nucleotide sequence ID" value="XM_008091209.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q468"/>
    <dbReference type="STRING" id="645133.E3Q468"/>
    <dbReference type="GeneID" id="24405889"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00524"/>
    <dbReference type="eggNOG" id="ENOG502SQUP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053359_1_3_1"/>
    <dbReference type="OrthoDB" id="199599at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ25380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="158" mass="17247" checksum="27011B39DA808D69" modified="2011-01-11" version="1">MQPRKEQEDARIGQPRPQPQSGHDETTKEETQTSATGPSAHGPASTAKLRAIRQFWGEHASVVVDFDTCRDHLVQLFAIQPSDSGFGYAAIGKPLDTACYCFAMCVALLGALRVWRIQHVLLLGKTLSGRFEIMTIAAGCLMLSVVFIGFSITLDIVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4C0</accession>
    <name>E3Q4C0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BolA-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00576</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BolA/IbaG family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089452.1">
        <property type="nucleotide sequence ID" value="XM_008091261.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4C0"/>
    <dbReference type="STRING" id="645133.E3Q4C0"/>
    <dbReference type="GeneID" id="24405941"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00576"/>
    <dbReference type="eggNOG" id="KOG2313">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109462_2_0_1"/>
    <dbReference type="OrthoDB" id="411584at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044572">
        <property type="term" value="P:[4Fe-4S] cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.90">
        <property type="entry name" value="BolA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002634">
        <property type="entry name" value="BolA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036065">
        <property type="entry name" value="BolA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46230:SF7">
        <property type="entry name" value="BOLA-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01722">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82657">
        <property type="entry name" value="BolA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="109"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ25432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="134" mass="14803" checksum="C115F3B986FBE6F4" modified="2011-01-11" version="1">MLRRYALGFSAGAARPLGTMSSATPVEDAIRSKVTAAFSPTTLEIYNDSHLHSHHKAMAGSTSKETHFRLVITSESFRSKMQSARHRMVYALLREEMAREGGIHALQLKTLTPEEEERQNAKKAAEAQSSEDSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4D1</accession>
    <name>E3Q4D1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">G-patch domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00587</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089463.1">
        <property type="nucleotide sequence ID" value="XM_008091272.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4D1"/>
    <dbReference type="STRING" id="645133.E3Q4D1"/>
    <dbReference type="GeneID" id="24405952"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00587"/>
    <dbReference type="eggNOG" id="ENOG502S8NF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082196_0_0_1"/>
    <dbReference type="OrthoDB" id="3366546at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050656">
        <property type="entry name" value="PINX1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23149">
        <property type="entry name" value="G PATCH DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23149:SF33">
        <property type="entry name" value="PROTEIN TMA23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="123"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="225" mass="25055" checksum="3FD0E546C71E236A" modified="2011-01-11" version="1">MDAHALLSAQGWRGKGHSLHATDDSIGLAKPLLLNRKDNTKGLGTKAHFTSDTWWMNAFDEQLQGLDTSKKGQVMQTVTQGRLNQIEKVSGGKWMLYASFVRGGFLEGTIQEHERKALEEHSGASTPESEETTTSSESEAEASPKKNKEKKERGETKEERRARRAAKRARKAAREARRQARGAKKASKASSGDRDRKESKEERRARRQAKKAKREARKAKKGGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4G1</accession>
    <name>E3Q4G1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Histidine biosynthesis trifunctional protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="19">Phosphoribosyl-AMP cyclohydrolase</fullName>
                <ecNumber evidence="19">3.5.4.19</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="19">Phosphoribosyl-ATP pyrophosphohydrolase</fullName>
                <ecNumber evidence="19">3.6.1.31</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="19">Histidinol dehydrogenase</fullName>
                <shortName evidence="19">HDH</shortName>
                <ecNumber evidence="19">1.1.1.23</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="22" type="ORF">GLRG_00617</name>
    </gene>
    <organism evidence="23">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 19">
            <text>1-(5-phospho-beta-D-ribosyl)-5'-AMP + H2O = 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:20049"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="EC" id="3.5.4.19"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 19">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + H2O = 1-(5-phospho-beta-D-ribosyl)-5'-AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22828"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="3.6.1.31"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18 19">
            <text>L-histidinol + 2 NAD(+) + H2O = L-histidine + 2 NADH + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:20641"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/9.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 3/9.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 9/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 19">In the C-terminal section; belongs to the histidinol dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.19" evidence="19"/>
    <dbReference type="EC" id="3.6.1.31" evidence="19"/>
    <dbReference type="EC" id="1.1.1.23" evidence="19"/>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089493.1">
        <property type="nucleotide sequence ID" value="XM_008091302.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4G1"/>
    <dbReference type="STRING" id="645133.E3Q4G1"/>
    <dbReference type="GeneID" id="24405982"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00617"/>
    <dbReference type="eggNOG" id="KOG2697">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG4311">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006732_0_0_1"/>
    <dbReference type="OrthoDB" id="1703565at2759"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00007"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004399">
        <property type="term" value="F:histidinol dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004635">
        <property type="term" value="F:phosphoribosyl-AMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004636">
        <property type="term" value="F:phosphoribosyl-ATP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06572">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11546">
        <property type="entry name" value="NTP-PPase_His4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.1080:FF:000002">
        <property type="entry name" value="Histidine biosynthesis bifunctional protein HisIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.1300:FF:000001">
        <property type="entry name" value="Histidine biosynthesis trifunctional protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.810:FF:000002">
        <property type="entry name" value="Histidine biosynthesis trifunctional protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1980:FF:000050">
        <property type="entry name" value="Histidine biosynthesis trifunctional protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1980:FF:000001">
        <property type="entry name" value="Histidinol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1080">
        <property type="entry name" value="MazG-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1980">
        <property type="entry name" value="Nitrogenase molybdenum iron protein domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.810">
        <property type="entry name" value="Phosphoribosyl-AMP cyclohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01024">
        <property type="entry name" value="HisD"/>
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    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
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    <dbReference type="InterPro" id="IPR008179">
        <property type="entry name" value="HisE"/>
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    <dbReference type="InterPro" id="IPR016298">
        <property type="entry name" value="Histidine_synth_trifunct"/>
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    <dbReference type="InterPro" id="IPR001692">
        <property type="entry name" value="Histidinol_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012131">
        <property type="entry name" value="Hstdl_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021130">
        <property type="entry name" value="PRib-ATP_PPHydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002496">
        <property type="entry name" value="PRib_AMP_CycHydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038019">
        <property type="entry name" value="PRib_AMP_CycHydrolase_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00069">
        <property type="entry name" value="hisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03188">
        <property type="entry name" value="histidine_hisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21256:SF2">
        <property type="entry name" value="HISTIDINE BIOSYNTHESIS TRIFUNCTIONAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21256">
        <property type="entry name" value="HISTIDINOL DEHYDROGENASE HDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00815">
        <property type="entry name" value="Histidinol_dh"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF01502">
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    <dbReference type="Pfam" id="PF01503">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001257">
        <property type="entry name" value="His_trifunctional"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00083">
        <property type="entry name" value="HOLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101386">
        <property type="entry name" value="all-alpha NTP pyrophosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141734">
        <property type="entry name" value="HisI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00611">
        <property type="entry name" value="HISOL_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 19" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="13 19" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="16 19" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="11 19" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="15 19" id="KW-0520">NAD</keyword>
    <keyword evidence="10 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14 19" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Phosphoribosyl-AMP cyclohydrolase" evidence="21">
        <location>
            <begin position="222"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="393"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="403"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00005204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00008260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00049489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRNR" id="PIRNR001257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF01502"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EFQ25473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="866" mass="93565" checksum="A278C967427FB5ED" modified="2011-01-11" version="1">METTLPFPFLISVAVPPGLSKLDGLDREQVSILGAPFFEANDQTLEKFHNFLKQHNAEFRGYFDVTRISSRDDVVSLLDAGARMVFVSPENLAQYEEFGSRVGSVLSTADVTTKPASKHAVLVKDFDSATCDLGSFIERCKVEKLPNLFIKPVPESNLDHFVDIAKQCCAIPVLPSDGLTASKEEPKKLSLSKLISSFWKSDRPDGLIPTVVCDESGTALGLAYSSAESVGEALRTRTGVYQSRKRGLWVKGATSGDTQELVRIALDCDNDTLKFVVRQKGGFCHLDQHGCFGDLSGIPRLEQTLQSRKKSAPAGSYTARLFSDEKLLRAKIMEEAEELCDAKTPQEVAFEAADLIYFALTKAVSAGVSLADIERNLDAKSFKVKRRTGDAKGKWAEKEGIKPSSATSPAAAAAPAPAPKDDESDRITMRRYDLTKSSAAEIGEVLKRPSQKSPDAILNIVKPIIDEVRDGGDKAVLSYTHKFEKATSLTSPVLKAPFPKEAMQLSPESIKAIDISFENIRKFHAAQKEDKPLQVETMPGVVCSRFSRPIERVGLYVPGGTAVLPSTALMLGVPAMVAGCQKIVIASPPRADGSLTPEIVYVAHKVGAESIVLAGGAQAVAAMAYGTESVTKVDKILGPGNQFVTAAKMFVSNDTNAGVSIDMPAGPSEVLVIADKDANPAFVASDLLSQAEHGVDSQVVLIAIDLTEQQLQAIEDELHSQAMALPRVDIVRGAIAHSVTIQVKTVDEAMRISNDYAPEHLILQVKDAEKVTEKVMNAGSVFIGEWTPESVGDYSAGVNHSLPTYGYAKQYSGVNLASFVKHITSSNLTAEGLRNVGEAVMQLAKTEQLEAHRRAVEIRIDHMNRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5M6</accession>
    <name>E3Q5M6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_01137</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090013.1">
        <property type="nucleotide sequence ID" value="XM_008091822.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5M6"/>
    <dbReference type="GeneID" id="24406502"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01137"/>
    <dbReference type="eggNOG" id="ENOG502T4ME">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2637937_0_0_1"/>
    <dbReference type="OrthoDB" id="4844985at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="77" mass="7633" checksum="BE75A67F64C9F30E" modified="2011-01-11" version="1">MSSWESKNVSPFENSSTPNKWGNTSGGCSEGDPNGPTGTGANASNTKGGHKDQISAASVKGGRPSGGGYGHHGGSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5P9</accession>
    <name>E3Q5P9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_01684</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090560.1">
        <property type="nucleotide sequence ID" value="XM_008092369.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5P9"/>
    <dbReference type="GeneID" id="24407049"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01684"/>
    <dbReference type="HOGENOM" id="CLU_1844927_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="139" mass="15287" checksum="6FC592D173FBC5F6" modified="2011-01-11" version="1">MLGTALLPVPWPGTSNYDAIRPKFFPLLGLSFLVYHYSFAIRLVFALSGTFRSVSVAVTTSPIHLSIGWHHFPSISLRDYSRHGNQPGTNSVTRSLQAPSNPTSLGLVNESGSTAGRRTDLDHASWRKWRAVLECSGTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5Q4</accession>
    <name>E3Q5Q4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF3602 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_01689</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090565.1">
        <property type="nucleotide sequence ID" value="XM_008092374.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5Q4"/>
    <dbReference type="GeneID" id="24407054"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01689"/>
    <dbReference type="eggNOG" id="ENOG502SB08">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115686_0_0_1"/>
    <dbReference type="OrthoDB" id="2537432at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053203">
        <property type="entry name" value="Cisplatin_resist-associated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022024">
        <property type="entry name" value="DUF3602"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34693:SF3">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34693">
        <property type="entry name" value="PROTEIN PAR32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12223">
        <property type="entry name" value="DUF3602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="138" mass="14062" checksum="14AE547B9DE1A76F" modified="2011-01-11" version="1">MTAEVSHGRGGAGNMAADDTPYVDGEVVRAGPEGSHGTGAFSSGRGGAGNIADTNSEPAPRADKDVVPEEAYRPSTEGQDYHVGRGGAGNAVETEKLATHKDIDHEKKAAAQARAEGSAGVSVADKLKAKVLAPFHKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q678</accession>
    <name>E3Q678_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Mannan polymerase complexes MNN9 subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_01470</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the ANP1/MMN9/VAN1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090346.1">
        <property type="nucleotide sequence ID" value="XM_008092155.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q678"/>
    <dbReference type="STRING" id="645133.E3Q678"/>
    <dbReference type="GeneID" id="24406835"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01470"/>
    <dbReference type="eggNOG" id="ENOG502QRPX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017872_4_0_1"/>
    <dbReference type="OrthoDB" id="2405412at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000136">
        <property type="term" value="C:mannan polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000009">
        <property type="term" value="F:alpha-1,6-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000032">
        <property type="term" value="P:cell wall mannoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000017">
        <property type="entry name" value="Mannan polymerase II complex ANP1 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052086">
        <property type="entry name" value="Mannan_Polymerase_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43083:SF6">
        <property type="entry name" value="MANNAN POLYMERASE COMPLEXES SUBUNIT MNN9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43083">
        <property type="entry name" value="MANNAN POLYMERASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03452">
        <property type="entry name" value="Anp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="42"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ26326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="367" mass="41314" checksum="4695B6C05B516609" modified="2011-01-11" version="1">MARPMGSVRLKKANPVTLLLGAVLCIFIIVFLVGPSKSTTAESSGTASHHLSPPTAPYRKKAKGDTRPPPVVHYNLNNVTITTDPIGNRESVLILTPMARFYQEYWDNLLRLNYPHDLISLGFILPKTKEGNAATAALQDQITKTQRSDKNSFKSIVILRQDFEPAIASQDEGERHKMENQKARRASMSKARNSLLFTTLGPQTSWVLWLDADIVETPPSLIQDLAAHDKAVIVPNCFQRFINPETKKMEERPYDFNSWQDSEIAQKMAETMGPDDILLEGYKDMPTYRALMAYLGTDENDKKVEIPLDGVGGTALLVKADVHRDGAMFPPFSFYHLIETEGFAKMAKRLGWQPFGLPNYRVYHYNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q687</accession>
    <name>E3Q687_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Oxysterol-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_01479</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the OSBP family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090355.1">
        <property type="nucleotide sequence ID" value="XM_008092164.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q687"/>
    <dbReference type="STRING" id="645133.E3Q687"/>
    <dbReference type="GeneID" id="24406844"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01479"/>
    <dbReference type="eggNOG" id="KOG2210">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012334_4_2_1"/>
    <dbReference type="OrthoDB" id="14833at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032541">
        <property type="term" value="C:cortical endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.160.120:FF:000007">
        <property type="entry name" value="Oxysterol binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.2720:FF:000001">
        <property type="entry name" value="Oxysterol-binding OBPalpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2720">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037239">
        <property type="entry name" value="OSBP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000648">
        <property type="entry name" value="Oxysterol-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018494">
        <property type="entry name" value="Oxysterol-bd_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972:SF102">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01237">
        <property type="entry name" value="Oxysterol_BP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144000">
        <property type="entry name" value="Oxysterol-binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01013">
        <property type="entry name" value="OSBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="4" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="334"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="418"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="459"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="524"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ26335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="541" mass="60133" checksum="F57F665CF314833F" modified="2011-01-11" version="1">MLTSWLSNPPASNRSSVDEARGAAAAEDDDTLVVEPDQGNVLGHIISQLRPGADLSRVVLPTFILEPRSMLERITNFMCHPEMLLPIPEIDDPLLRFVSVVKFYLSGWHIRPPGVKKPLNPILGEIFTCYWDLPDNTKAYYVSEQTSHHPPKSSYFYMVPEHHIRVDGTLKPRSKFLGNSAASMMEGTAVLTLLNRGKDKSKGERYILTQPNMYARGILFGKMKYELGDHSFVRCPELDLVADIEFKTKGWVSGTYNAIGGYIKHESTGEVLYELSGLWSEEMYVKDVKTGHKEMFFNARKSKPSNPLVRPIEEQDERESQKLWLATAQAVKDRNHELATDEKTKVEDRQREEREIRAREGIEWHPRLFRSVHAGPDGYDEGEEELEWIINAKIDSTTPEGQTKQILAIYPILPGQKASATTADPSHGPLTAEVQSPAEQAPVVRQQDGGNDLIDFGDAPATTSAAATPSTPATEPSAAAPPVAQEQRSGSKDIESMLNKTGSKPAEGPLMDFTTDMKNVPPLKRADTSEDSFHDALEPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6G7</accession>
    <name>E3Q6G7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Beta-eliminating lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_01559</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the threonine aldolase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090435.1">
        <property type="nucleotide sequence ID" value="XM_008092244.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6G7"/>
    <dbReference type="STRING" id="645133.E3Q6G7"/>
    <dbReference type="GeneID" id="24406924"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01559"/>
    <dbReference type="eggNOG" id="KOG1368">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029381_1_0_1"/>
    <dbReference type="OrthoDB" id="10261951at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008732">
        <property type="term" value="F:L-allo-threonine aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006545">
        <property type="term" value="P:glycine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006567">
        <property type="term" value="P:L-threonine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000030">
        <property type="entry name" value="Low-specificity L-threonine aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001597">
        <property type="entry name" value="ArAA_b-elim_lyase/Thr_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023603">
        <property type="entry name" value="Low_specificity_L-TA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097:SF9">
        <property type="entry name" value="L-THREONINE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097">
        <property type="entry name" value="L-THREONINE ALDOLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01212">
        <property type="entry name" value="Beta_elim_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017617">
        <property type="entry name" value="Thr_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aromatic amino acid beta-eliminating lyase/threonine aldolase" evidence="6">
        <location>
            <begin position="22"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="5">
        <location>
            <position position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR017617-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ26415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="377" mass="40633" checksum="2C1BB6A3A793F389" modified="2011-01-11" version="1">MTSNESSAMLWGSPKATGAAFDFRSDVITTPSRGMLLAIARTTLHDDVYGEDSTTRDFEEEMAKICGHESAAFTLSGTMANQLALRALLHQPPHAILADASSHIIHWEAGGVAHLSGAMVQGIRPRNGLYLTLDDVKKHAAVTDDVHKCPTRVISIENTCSGIIIPLKELQRIKEWASAHGIAVHMDGARLWEVVSAGAGSLDDFGRCCDVLTVDFSKNLGAPMGAMVLGTSGLIKSLRRLRKSIGGGMRQAGVLVAAARQAVVENFGLGPRDSRAVLDISRTMAQEVGRMWAVRGGIVLKPIETNMVWLDLGGCGIETSEWNETGRRYSIKLDGKRVMLHHQISDLAIKRLGAVMDEVLSRVRQTAVLGAAPKARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6I7</accession>
    <name>E3Q6I7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Dipeptidyl-peptidase V</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_01579</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S9C family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090455.1">
        <property type="nucleotide sequence ID" value="XM_008092264.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6I7"/>
    <dbReference type="STRING" id="645133.E3Q6I7"/>
    <dbReference type="MEROPS" id="S09.012"/>
    <dbReference type="GeneID" id="24406944"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01579"/>
    <dbReference type="eggNOG" id="KOG2100">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008615_0_1_1"/>
    <dbReference type="OrthoDB" id="416344at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000028">
        <property type="entry name" value="S9 family peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42776:SF13">
        <property type="entry name" value="DIPEPTIDYL-PEPTIDASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42776">
        <property type="entry name" value="SERINE PEPTIDASE S9 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="7">
        <location>
            <begin position="479"/>
            <end position="688"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ26435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="698" mass="77964" checksum="B0D40157B7E25AFF" modified="2011-01-11" version="1">MMTIQASKFTPEVLLSAPRRSPGIPNPAGTKVLYTVSTYSFDSHSKTSQIRVLDVESGHSTLLYEEASYSDATWISDQEVLMLRSGDKGATSLLLGDVTMPSVVTRIGHFEGSLSSLKAKPLSDDKVAIAVCVLTTPDGAMYNPAAEKKQHTTGKVYSSLFVRHWDSWVSENHNAIWYGLLKKEDKTYKLEEPGLVNALKGTKLQSPVPPFGGAGDFDIGKNGIVFVARDPEISPAIYTKTDLYFVPLKSFTEKEPPVPQVVKTSKLRGYSASPVFSRDGKKVAFTRMKSDQYETDKPRLMLIPNVFDLASVQEFYQTDDGAGGWDARPEWITWSKDDSELYVSAEEHGRMKLWKLPSTPHEVKDLPAAIYGEGSVIEAKLLGDEGEKLLISTSSRVENSAYSVLNPVNKETDLVSSSSKHGKSFGLSQSQCDEFWFKGAEGYDVHALVLKPSNFDENKKYPLAFLIHGGPQAAWTDSWSTRWNPAIFAEQGYIAVMPNPTGSTGYGQQHTDNIQNEWGGRPYVDLVKCFDHIEKNIPYIDSGNAVALGASYGGYMINWIQGHELGRKFKALVCHDGVFSTLNQWSTEELFFPLHDFGGLLWENREGYEKWDPAHHLGQWSTPQLVIHNELDYRLPISEGLAMFNVLQTRGVPSKMLMFPDENHWVLKPENSLLWHREVLDWINKYTGIGKSAELAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6J9</accession>
    <name>E3Q6J9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_01591</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090467.1">
        <property type="nucleotide sequence ID" value="XM_008092276.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6J9"/>
    <dbReference type="GeneID" id="24406956"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01591"/>
    <dbReference type="eggNOG" id="ENOG502SIH3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036233_0_0_1"/>
    <dbReference type="OrthoDB" id="5413188at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="347"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ26447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="425" mass="45170" checksum="8F372E5660BC9607" modified="2011-01-11" version="1">MDGQQRDERAGQNFQNGRMLGNGAQPAVGPRRRNDESWVEISSQPSSSSLSSIGDEIVTTGLRVGGSMAARRRRLHHQSQPVPRSFHVDQTAIHAGTSSQEEYEESESEEDRCLTSSTENIQPSVRAPFHQQQPPQEESEDSDDSDEIATALGRVPDDPVFRPQPNAFSHPPSGLNRSHSANSAIHQHPHSGVRPALSQRSQTRVHRSPPNFMSPAYQADNDAALRASLTTLLSCAAAARGLPKYKDTERQCATPAHAGVGPSSQPVELRLMPESELMAERPTQPQGAPSAQSPTTQPGKTTSSAPPSPKSAGVDRHKRTSSQTRSSRAAKKKKVSAGDDTLISPTLLTWVVSAGVVVLVSVVGFGAGYVIGREVGRQEALSAGVGVNASTVADSSSCGREVIRSSGGGLRRLRWGAGVGRSVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7D4</accession>
    <name>E3Q7D4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_02592</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090792.1">
        <property type="nucleotide sequence ID" value="XM_008092601.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7D4"/>
    <dbReference type="GeneID" id="24407957"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02592"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_27_5_1"/>
    <dbReference type="OrthoDB" id="2130629at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718:SF10">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G06760)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="27"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="153"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="225"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="337"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="362"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="387"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="424"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="471"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="29"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ26772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="502" mass="53521" checksum="46F65A5204174B95" modified="2011-01-11" version="1">MDIPLNEAGAEPRQSLPSRNVSVAKSVTVIVTLAGINFLNTMGSGILIAALPRIASDVGLDESLMLWPAAVYSLAAGCLLLIFGAVADVVGAKFMWVAGSYLCAVFTVAVGLSQTGIQIIVFRTCMGMSISACLPTAMAFITKTFPKGGWRNVAFSMNGIGFPLRYALGLVLGGIFTDTIGWRWGFYMMAIINFCLSTAAIWSLPSVYQPSEKKWSRRLAEDIDWIGAVIMSVALGLLLYVLAMTTSSYTKIGDPANIALLAVAVALLVAFPFWMNRQTAKGSPALIPNRLWRNASFTSICAAILLCWASLNAIQYFIMLYFQQVQGISALQSSLRFLPHVVMGAAVNVAAAWLVSRVKVQTLGAVSAVITAIAPFLMATVDLDGYYWFAPFWAMILSPVNADALFTVSNLIISDAFPADLQSLAGGVFSEIGQIGNAVGLAVTAAIAASVTEHSDIVGRTKEARMAGYRAAFWTIFAATGAVLVIVLWGLRKGGMAGKKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7J4</accession>
    <name>E3Q7J4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Pantothenate kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_02652</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090852.1">
        <property type="nucleotide sequence ID" value="XM_008092661.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7J4"/>
    <dbReference type="STRING" id="645133.E3Q7J4"/>
    <dbReference type="GeneID" id="24408017"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02652"/>
    <dbReference type="eggNOG" id="KOG2201">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011154_3_1_1"/>
    <dbReference type="OrthoDB" id="498611at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004594">
        <property type="term" value="F:pantothenate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd24123">
        <property type="entry name" value="ASKHA_NBD_PanK-II_Pank4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000115">
        <property type="entry name" value="Pantothenate kinase PanK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.510:FF:000005">
        <property type="entry name" value="Probable pantothenate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.510">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004567">
        <property type="entry name" value="Type_II_PanK"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00555">
        <property type="entry name" value="panK_eukar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12280:SF20">
        <property type="entry name" value="4'-PHOSPHOPANTETHEINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12280">
        <property type="entry name" value="PANTOTHENATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03630">
        <property type="entry name" value="Fumble"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="84"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="350"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="22"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="86"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="350"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ26832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="521" mass="57404" checksum="DD99910743C3C18E" modified="2011-01-11" version="1">MGPAPEDGGSAVEDPRPNDKLNNNNNNDNDNNTITNTNTSSSEPAVLAGAEIRTRARTMTSTEEIDNTIIRPGSVRINVKGAFIVDPDSSSPSNNGRGSPTHHETSDIRLPNHHAVVSHIAVDIGGSLIKLVYFTREPHSADPGGRLNFLNFETDRIDDCIEFMRHLKDKQQTLNGSKPNELSVMATGGGAFKFYDKMRDVLGVDVLREEEMECLIIGLDFFITEIPREVFTYSETDPMHFVSPSENIYPYLLVNIGSGVSLLKVSGPREYQRVGGTSLGGGTLWGLLSLLTGARTFDEMLDLSERGDNAKVDMLVGDIYGGDYGKIGLKSTTIASSFGKVFRMKRTAENEAEDHGGLHNRDNKNTHCSSSDPVEPAGGGHQDAAAEHASDQPFSGADISRSLLYAISNNIGQIAFLQSQIHNLDHIYFGGSFIRGHRQTINTLSYAIKFWSQGKKQAYFLRHEGYLGSVGAFLKRQPHNWGRRGSFEQAEPLQRRLQDRRIHDAEMQSLVDDYASESGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8A4</accession>
    <name>E3Q8A4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutathione S-transferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_02287</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091136.1">
        <property type="nucleotide sequence ID" value="XM_008092945.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8A4"/>
    <dbReference type="STRING" id="645133.E3Q8A4"/>
    <dbReference type="GeneID" id="24407652"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02287"/>
    <dbReference type="eggNOG" id="KOG0867">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011226_15_0_1"/>
    <dbReference type="OrthoDB" id="2098326at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03046">
        <property type="entry name" value="GST_N_GTT1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051:SF9">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13410">
        <property type="entry name" value="GST_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="6"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="112"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ27116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="268" mass="30298" checksum="F2B8488AF05DED9C" modified="2011-01-11" version="1">MTTEQKPKVKLYWLEQSRAQNILWLLEELKVDYEVEVFHRNKQTLLAPPELAKIHPLGKSPVIDIYPTGSGEPIRLAESGYMTSYLCEHFGQNTNLIPKKWKDGQEGKLGGETEEFSRCQYLLHYIEGSLLPVLTMTLVIGALKSDNVPFFVRPITSVVANKIYSMVIFPNAQKHLALLDQMLETSPNGGKYMCGEHLSAADILLSFALIAAEPRFDTLGSWPGGSSRVAHPRVFEYIDRLKKEPGYQRSADKIREIEGKFEPTISKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8J1</accession>
    <name>E3Q8J1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1295 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02374</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091223.1">
        <property type="nucleotide sequence ID" value="XM_008093032.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8J1"/>
    <dbReference type="GeneID" id="24407739"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02374"/>
    <dbReference type="eggNOG" id="KOG4650">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043418_0_1_1"/>
    <dbReference type="OrthoDB" id="201504at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010721">
        <property type="entry name" value="UstE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251:SF23">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE (DUF1295)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06966">
        <property type="entry name" value="DUF1295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="350" mass="40330" checksum="D3AC26C8050D7F89" modified="2011-01-11" version="1">MALPSVSSLEECSEWARVAEPFIPQLLDLPRKIAASPHSLPQIYLETNPLVSGFAFSLLIALITLGLSEYHRNYSQIDRLWSLLPNWYVLHTAAWAYLNGEPSHRVALAGVATTLWSARLTFNYWRKGGYERGSEDYRWEIVRDYVPGWVFFIFNVTFISFYQSILLFSFSAPPAYALFLASRIEPEVTAADWSFFSIIAGLVLSEFISDGQQWDYQNAKAAYKKDAKVPRGWAQEDLDRGFITNGLWSYSRHPNFFAEQMVWFVLYQWSCYATKVLYSYTGAGAALLIMLFQGSTWLTEFITSGKYPEYKHYQKQVGMFMPKSLFPYSKPQPKVIRTSELAERQSKKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q912</accession>
    <name>E3Q912_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">argininosuccinate lyase</fullName>
            <ecNumber evidence="4">4.3.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Arginosuccinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_02021</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-(N(omega)-L-arginino)succinate = fumarate + L-arginine</text>
            <dbReference type="Rhea" id="RHEA:24020"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:57472"/>
            <dbReference type="EC" id="4.3.2.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 3/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.1" evidence="4"/>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091546.1">
        <property type="nucleotide sequence ID" value="XM_008093355.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q912"/>
    <dbReference type="STRING" id="645133.E3Q912"/>
    <dbReference type="GeneID" id="24407386"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02021"/>
    <dbReference type="eggNOG" id="KOG1316">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027272_2_1_1"/>
    <dbReference type="OrthoDB" id="2561043at2759"/>
    <dbReference type="UniPathway" id="UPA00068"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004056">
        <property type="term" value="F:argininosuccinate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042450">
        <property type="term" value="P:L-arginine biosynthetic process via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01359">
        <property type="entry name" value="Argininosuccinate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.275.10:FF:000002">
        <property type="entry name" value="Argininosuccinate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.40.30:FF:000001">
        <property type="entry name" value="Argininosuccinate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.200.10:FF:000025">
        <property type="entry name" value="Argininosuccinate lyase chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.40.30">
        <property type="entry name" value="Fumarase/aspartase (C-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.200.10">
        <property type="entry name" value="Fumarase/aspartase (Central domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="entry name" value="Fumarase/aspartase (N-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00006">
        <property type="entry name" value="Arg_succ_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029419">
        <property type="entry name" value="Arg_succ_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009049">
        <property type="entry name" value="Argininosuccinate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00838">
        <property type="entry name" value="argH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43814">
        <property type="entry name" value="ARGININOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43814:SF1">
        <property type="entry name" value="ARGININOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14698">
        <property type="entry name" value="ASL_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00145">
        <property type="entry name" value="ARGSUCLYASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="L-aspartase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumarate lyase N-terminal" evidence="6">
        <location>
            <begin position="17"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="Argininosuccinate lyase C-terminal" evidence="7">
        <location>
            <begin position="375"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ27526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="467" mass="52204" checksum="DC42F998D946C8E1" modified="2011-01-11" version="1">MATKKTDAPATNMLWGGRFTGGIDPLMHKYNASIRYDKALYREDILGSIAFARANSKVGIITDDEFKTIERGLLEVMEEWKQGTFAIMPNDEDVHTANERRLGELIGKDTAGKLHTGRSRNEQVVCDMRMWLRDRIRDIDGQLVAFLQVLAKRAEAEIDYLMPGYTHLQLAQPVRWAQWIMSHASSFKQDLERLRQVFERVNLSPLGCGALAGNVFGIDRDAIAAELGFSGITLNSMNTSGDRDFIIEFLNWNSMFTSHISRWAEDLILYSTHEFGFCRLADSYSTGSSLMPNKKNADSLELLRGKSGRAFGQMAGLMMTVKGLPTCYNKDLQEGWEPMLDSVQTVLDSLGIANGVFATMAVRPERMLAALDKTMLATDVAEWLVRNGCPFREAHHISGRIVALSESTETPMDKLTLEQLQAIDGRFTADIIKAFEYESSVEAKSARGGTSRSAVLQQIQELYAILD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9G1</accession>
    <name>E3Q9G1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_01835</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091360.1">
        <property type="nucleotide sequence ID" value="XM_008093169.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9G1"/>
    <dbReference type="GeneID" id="24407200"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01835"/>
    <dbReference type="eggNOG" id="ENOG502SSXE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094698_0_0_1"/>
    <dbReference type="OrthoDB" id="3862662at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="139"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="212" mass="22801" checksum="33390115C3FC7833" modified="2011-01-11" version="1">MATPCKARSPASLVDRGNEGVTESYLSVSNAAMNRGDASIQSKARGIPNGYLNKLETRLAETEAALFRALSGVLDSPGSGSASSPVLLPQAAWTPRQNKVDRVKEWELLPLQTPNEIEAWFRSKAAEQSDPVPEPPDASPQSPVSSVSDSVLAPHPVRDSDSMPAQRPLLDAVIEPRLRSMTPIATTPVNEVPSDSVSKAKELSKSQRNLYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QA62</accession>
    <name>E3QA62_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02894</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091770.1">
        <property type="nucleotide sequence ID" value="XM_008093579.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QA62"/>
    <dbReference type="STRING" id="645133.E3QA62"/>
    <dbReference type="GeneID" id="24408259"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02894"/>
    <dbReference type="eggNOG" id="ENOG502SMEB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016811_0_0_1"/>
    <dbReference type="OrthoDB" id="5343383at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="334"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="656" mass="73625" checksum="7F5D8B69F968E31A" modified="2011-01-11" version="1">MAVSDAFYYDRDEIAQSLAAYYSSPPTEGWSDLELDVDALRALRRSDKVIDLLRHIPYIKPCKSGDKPVQWPILVRSRAIRYLRDDGDFSNWSARGGDGLAELANAPFDQTPAGPMDLPSDVVALSRGYASSDFGSPWCIIDCETGILTPYTSGTGPTDKPWQTSRCSARVFFDEMTSFLKSKTIIALPPVGDLEPEIMGSESDQKVDVRQKFQWIYQARGWATFEEDPSSWRREECIEVLKRFRIELWEAEKKRLAHEADFDDPKDEDFEDPDSDAGSEASQSETATEDVDTALEDEDISVDVSKEELAEVWADLDETEYMMIDEELKGEGIQHAFHPSKPPQRLARAPSSENNGPGASQVLDQRRCNDSIEMMAGAIKSQYLTLSRAAFFPPSMVETAPDSGWSDDVFPAEELEMLGYSDKAVSLLRHLPYLGFDEHFWEVLPGGQPIRYLRDAELFEDVPRDKPRRDSLRKLGLSPYDEAMPADVVVLSSPNQDSWRGTWWMIDAGRGVIFCESGPKTQVEAPANSYEPESIVTYLEKVVSKLRGLEIVPIPGLGPDENQDPVIWAEPNWERGADASAEMSEADRRIILPAKSGIGLEAARKVYRDYGWPDENSFRRDECREALVRLRQTTIYGEGLADDSVDEDTDVAMDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAM4</accession>
    <name>E3QAM4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Actin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_03056</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the actin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ27912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091932.1">
        <property type="nucleotide sequence ID" value="XM_008093741.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAM4"/>
    <dbReference type="SMR" id="E3QAM4"/>
    <dbReference type="STRING" id="645133.E3QAM4"/>
    <dbReference type="GeneID" id="24408421"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03056"/>
    <dbReference type="eggNOG" id="KOG0676">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027965_0_2_1"/>
    <dbReference type="OrthoDB" id="5132116at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10224">
        <property type="entry name" value="ASKHA_NBD_actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.36.70:FF:000001">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000291">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000001">
        <property type="entry name" value="Actin, muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000404">
        <property type="entry name" value="Major actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000058">
        <property type="entry name" value="Putative actin-related protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004001">
        <property type="entry name" value="Actin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00406">
        <property type="entry name" value="ACTINS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00432">
        <property type="entry name" value="ACTINS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ27912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="375" mass="41541" checksum="EEC0077D459C0424" modified="2011-01-11" version="1">MEEEVAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHHGIMIGMGQKDSYVGDEAQSKRGILTLRYPIEHGVVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPINPKSNREKMTQIVFETFNAPAFYVSIQAVLSLYASGRTTGIVLDSGDGVTHVVPIYEGFALPQAIARVDMAGRDLTDYLMKILAERGYSFSTTAEREIVRDIKEKLCYVALDFEQELQTASQSSSLEKSYELPDGQVITIGNERFRAPEALFAPSVLGLESGGIHVTVFNSIMKSDVDVRKDLYGNIVMSGGTTMYPGLSDRMQKEITSLAPSSMKVKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAU3</accession>
    <name>E3QAU3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphorylase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_03125</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ27981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092001.1">
        <property type="nucleotide sequence ID" value="XM_008093810.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAU3"/>
    <dbReference type="STRING" id="645133.E3QAU3"/>
    <dbReference type="GeneID" id="24408490"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03125"/>
    <dbReference type="eggNOG" id="ENOG502R7S0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_34_22_1"/>
    <dbReference type="OrthoDB" id="20872at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="entry name" value="Nucleoside phosphorylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053137">
        <property type="entry name" value="NLR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082:SF6">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082">
        <property type="entry name" value="ATP/GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="Purine and uridine phosphorylases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleoside phosphorylase" evidence="1">
        <location>
            <begin position="14"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="344" mass="37571" checksum="0500C363F0FFF242" modified="2011-01-11" version="1">MTGRARARQREDFRIAIICALPLEYDAVTFAFDEIWGDDDGRPANAPGDSTPYTTGRMGSHNVVLLLLPGMGKVNATGAAARLQSSYNGIKLAILCGICGGVPSPGTKDELFLGDVVISKSVLQCDLGRKYPDKFVLKDTIEESLGRPSREVRTLIAFLETRLGRSRLQHRASQVLEQVQQKAHKEYQDLYRRPDAAYDRLFEPDYLHRHQNSSPCGCSEAGACNVALSASCEALQCDTSRLVSRSRLEARQMPGAGDAVASQELRFVVGRVGSADTVMKAGLDRDRIAKEHGLVAFEMEGAGVWDEFPCVVVKSVCDYADSHKNKRWQDFAAAAAASMAKALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QB21</accession>
    <name>E3QB21_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Actin lateral binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_03203</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ28059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092079.1">
        <property type="nucleotide sequence ID" value="XM_008093888.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QB21"/>
    <dbReference type="STRING" id="645133.E3QB21"/>
    <dbReference type="GeneID" id="24408568"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03203"/>
    <dbReference type="eggNOG" id="KOG1003">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104738_0_1_1"/>
    <dbReference type="OrthoDB" id="128924at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070648">
        <property type="term" value="C:formin-nucleated actin cable"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990819">
        <property type="term" value="C:mating projection actin fusion focus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110085">
        <property type="term" value="C:mitotic actomyosin contractile ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003786">
        <property type="term" value="F:actin lateral binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044396">
        <property type="term" value="P:actin cortical patch organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902404">
        <property type="term" value="P:mitotic actomyosin contractile ring contraction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032220">
        <property type="term" value="P:plasma membrane fusion involved in cytogamy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.170:FF:000114">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Tropomyosin alpha-1 chain isoform 2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000533">
        <property type="entry name" value="Tropomyosin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19269">
        <property type="entry name" value="TROPOMYOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00261">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ28059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="161" mass="18681" checksum="45375D3DB4271F51" modified="2011-01-11" version="1">MDRIKEKMNQLRLEADDNAAKVEELQAKVKSLEQENLSKEQEITSLQHKNGLLEGEIEKLETAVKDFKKAADESTSTGTQNETLQRRLQLLEEEAEEADKTLREANEKLRQTDVKAGHFERKVQALEAERDQWESKYEEMAKKYTAVQKELEDFQNEIGNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QB70</accession>
    <name>E3QB70_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_03252</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ28108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092128.1">
        <property type="nucleotide sequence ID" value="XM_008093937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QB70"/>
    <dbReference type="GeneID" id="24408617"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03252"/>
    <dbReference type="eggNOG" id="ENOG502SUW6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102629_0_0_1"/>
    <dbReference type="OrthoDB" id="4502894at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="25"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="63"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ28108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="163" mass="17831" checksum="F6F5461D27FDFA88" modified="2011-01-11" version="1">MASLSYASGVFAIATWPARIVWKPVAFFVNVILVLFSPIVLMASYVIGWGQALLDFVASLEPLYTFLACGACIGIVAGLTLSCTSGIITTVFGMHEDRSKSLPPTPMPSTPLSERPGTGKTEDSSSYETDWHILNKPPPKRRRRTPGLWSQTIHEEDDDDSEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBF3</accession>
    <name>E3QBF3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">O-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_03436</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092312.1">
        <property type="nucleotide sequence ID" value="XM_008094121.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBF3"/>
    <dbReference type="STRING" id="645133.E3QBF3"/>
    <dbReference type="GeneID" id="24408801"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03436"/>
    <dbReference type="eggNOG" id="KOG1663">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067676_1_1_1"/>
    <dbReference type="OrthoDB" id="10251242at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050362">
        <property type="entry name" value="Cation-dep_OMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002935">
        <property type="entry name" value="SAM_O-MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10509:SF14">
        <property type="entry name" value="CAFFEOYL-COA O-METHYLTRANSFERASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10509">
        <property type="entry name" value="O-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01596">
        <property type="entry name" value="Methyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51682">
        <property type="entry name" value="SAM_OMT_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ28292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="251" mass="27179" checksum="973541AB5F521F86" modified="2011-01-11" version="1">MKSSAPVLYPNESVSQKVTAYAESHSTDLPAHIVAYHEHIETTQPETSMLMISNFQAQNHIWLAKLIGAKRILEIGVYVGYSGMIWSHAVGPDGTVTGLEFNADYAKEAEAAWAANGIKNASVVVGDALETLPALSPSEPYDLIFIDAQKSGYPAYLSTILAASPASGGKGRLLRPGGLIVADNVLRRGIVADDSDENPWAVGDKAYRAAYARSEDVDKLREFNAAVHDEPRLDSWLMPLYDGVHLARLVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBU9</accession>
    <name>E3QBU9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histone H1-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_03328</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008094013.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBU9"/>
    <dbReference type="STRING" id="645133.E3QBU9"/>
    <dbReference type="GeneID" id="24408693"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03328"/>
    <dbReference type="eggNOG" id="KOG4563">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028900_1_0_1"/>
    <dbReference type="OrthoDB" id="5587616at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034080">
        <property type="term" value="P:CENP-A containing chromatin assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006335">
        <property type="term" value="P:DNA replication-dependent chromatin assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051730">
        <property type="entry name" value="NASP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15081:SF1">
        <property type="entry name" value="NUCLEAR AUTOANTIGENIC SPERM PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15081">
        <property type="entry name" value="NUCLEAR AUTOANTIGENIC SPERM PROTEIN NASP -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="30"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="126"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="180"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="247"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="425"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="38"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="134"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="149"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="199"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="445"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="472"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ28184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="497" mass="53650" checksum="788A83798A9948DF" modified="2011-01-11" version="1">MADVTDHATIPSEVSAAEVPVAEVLAVEAVANPETKQDAPAPAQQDTPATAGEESEEDSNSKKVTLADLTAKGTALYAKKQYEDAAECFTKAAELQDEINGEMHPKNAEILFLYGRSVFKVGQSKSDVLGGKAGSEKKVEKPKTKAPKKAAVQAAPTDAPAESNTQRITEEGVAIVANDASGAQTVDKVEEKKPLFQFDGDENFDDESDDEEAEGEGEEEEEDDDLAVAFGVLDMARVLYNRQLEQLEKEEPNGKAQEQLDGDKLSIKHLPRYPDAIEDSRKSLKYKKELYTDDSEIIAEAHFKLSLALEFASVTTTQEEGEQAESKPFDEKLREEAANELEAAIRSTKLKLQNKEVELATMASPEDNEVTRATITDVKDMITDMEQRLVDLRKPPIDVNAALGGDGVGGILGAALGESTAQTQARVEEAKKTATDLTGLVRKKNKDEPKPADKPAVEAKATEVSANGEESNGIKRKAEDSAETDESAKKAKVEEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QC03</accession>
    <name>E3QC03_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ureidoglycolate hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_03382</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(S)-ureidoglycolate = urea + glyoxylate</text>
            <dbReference type="Rhea" id="RHEA:11304"/>
            <dbReference type="ChEBI" id="CHEBI:16199"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="ChEBI" id="CHEBI:57296"/>
            <dbReference type="EC" id="4.3.2.3"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092258.1">
        <property type="nucleotide sequence ID" value="XM_008094067.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QC03"/>
    <dbReference type="STRING" id="645133.E3QC03"/>
    <dbReference type="GeneID" id="24408747"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03382"/>
    <dbReference type="eggNOG" id="ENOG502S1JQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070848_0_0_1"/>
    <dbReference type="OrthoDB" id="10266039at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004848">
        <property type="term" value="F:ureidoglycolate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050385">
        <property type="term" value="F:ureidoglycolate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000256">
        <property type="term" value="P:allantoin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006144">
        <property type="term" value="P:purine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.480">
        <property type="entry name" value="Ureidoglycolate hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007247">
        <property type="entry name" value="Ureidogly_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024060">
        <property type="entry name" value="Ureidoglycolate_lyase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21221">
        <property type="entry name" value="UREIDOGLYCOLATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21221:SF1">
        <property type="entry name" value="UREIDOGLYCOLATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04115">
        <property type="entry name" value="Ureidogly_lyase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ28238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="270" mass="27422" checksum="AFD1D1FC1CFCEBDA" modified="2011-01-11" version="1">MPPTRLTVPLPVLVPAEPLTRFSFAPFGDVIENPHPEVLPAASLPPAVSASFSAVPANQGTAIKYQHVSAPLDLYAQAPSGAARPIVSLFSCAARALEPARPAAAAPPISTLLPYTTYAGPERGGRSASPSRAPPLHHPDLRPLAASDAVHAAAYLVIVAPTLAVAAAAGPETDALPAPATGGKGPGLPDLKRLKAFVAYPGQAVTYGAGTWHAPMVALGPQGTAIDFVVTQFASGVAVEDCQEVELDAASEGAGVVVQVPERMPPASKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCH8</accession>
    <name>E3QCH8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_03710</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092586.1">
        <property type="nucleotide sequence ID" value="XM_008094395.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCH8"/>
    <dbReference type="GeneID" id="24409075"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03710"/>
    <dbReference type="HOGENOM" id="CLU_2426888_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ28566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="91" mass="10209" checksum="932ECA432D533102" modified="2011-01-11" version="1">MRANRPGSQKSQAGAGCIRYVKGTVANLTMQPFADEESTMMDAERRGLCNGASVKYPGPSETNDSEAKRKSMLHDDDNDDEEWEREKKRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCI2</accession>
    <name>E3QCI2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CoA-transferase family III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_03714</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CoA-transferase III family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092590.1">
        <property type="nucleotide sequence ID" value="XM_008094399.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCI2"/>
    <dbReference type="STRING" id="645133.E3QCI2"/>
    <dbReference type="GeneID" id="24409079"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03714"/>
    <dbReference type="eggNOG" id="KOG3957">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021588_1_1_1"/>
    <dbReference type="OrthoDB" id="2308815at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10540">
        <property type="entry name" value="Crotonobetainyl-coa:carnitine coa-transferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052985">
        <property type="entry name" value="CoA-trans_III_biosynth/detox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003673">
        <property type="entry name" value="CoA-Trfase_fam_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023606">
        <property type="entry name" value="CoA-Trfase_III_dom_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48229:SF1">
        <property type="entry name" value="ALPHA METHYLACYL-COA RACEMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48229">
        <property type="entry name" value="CAIB/BAIF FAMILY ENZYME (AFU_ORTHOLOGUE AFUA_1G05360)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02515">
        <property type="entry name" value="CoA_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89796">
        <property type="entry name" value="CoA-transferase family III (CaiB/BaiF)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ28570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="578" mass="62969" checksum="5D95FC7A399C20F3" modified="2011-01-11" version="1">MVPKRPGSQRATTSYSVKEGSENALAALIAACQRQLPPEFVEHLRNVVFIAPQGDVPYFPCPLKEQEATASIKALEGMAAAALSDFRHGPQAQRHIEVDVARTACFLMSAYLTTVNGMDKGHPNVKAKIPDTDLNQAQSILYRRLSANLYETKDVGEYYHLHGSLEASRALNMIGLPAFNPELQGYSECIKTIETAMKCFSVQELEEMNRKEGQAGVPVLKKEQFSNTPHGKVLEQLPPLTVKPIESITPPAPFEPRRSSSGAEQCLSGIRVLELCRIIAGPTIGRSLAAHGASVLKVTSPNLPDVPFFQVDVNTGKHATSLHLKDPEDRATFESLLASADVILDGYRPGVVDRLGYGPEKLAVIAASRGKGFVYVAEDCFGGSELGVAKAEWAGRPGWQQIADCVTGVAWEQGHFMGLDAPVVPPFPMSDYGTGALGAVGAMAGLYRRATEGGSWACRTSLCQYDVFLLSLGAYPPEVQARLRKTHSPAFFDLRHHDSVDEVGKRALHSVKHLHPELFAEDLMHRAWSPGFDAEVRWPREAVRIGGLRVGHNRASRPNGADAPLWEDWEVQDDIVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCY5</accession>
    <name>E3QCY5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glycophorin A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_03901</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092777.1">
        <property type="nucleotide sequence ID" value="XM_008094586.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCY5"/>
    <dbReference type="STRING" id="645133.E3QCY5"/>
    <dbReference type="GeneID" id="24409266"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03901"/>
    <dbReference type="eggNOG" id="ENOG502SK6S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043314_0_0_1"/>
    <dbReference type="OrthoDB" id="5425848at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180318" description="Glycophorin A domain-containing protein" evidence="3">
        <location>
            <begin position="29"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="218"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="333"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="340"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="366"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="379"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ28757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="397" mass="41615" checksum="4EECB8C9AF08BC65" modified="2011-01-11" version="1">MSRRKHSVAAPLVAGFLLLASAPTLVSAHPYPLQNVANNLFYELGDKFMKRDCVQRCGVDSQYCCGSGEQCYTVNNIAGCSTINGGGGYGIFTTTWTETNTFTSTITTDWPATTKAGGGGAGGTCVPQHEGETACGSICCAVYQYCAYEGQCAQRAGWGGGITTVTSGGVTITTQFSAPYRITSTAATGTFASATATGTGTVVPVTDEGTGGGLSGGAIAGIVIGTLAGLGLLMLLCFCCIARGLWGLIFGGKKKKEHSRERVEVVEERYSRHGSRMPSAHSHRPSHTGWFAGGGRPAPAARRNEEKKEGAKWLGLGAAAATLLALLNVKKDKPARKPRSSYTDSYYSYTGTSPSESSSDSRTRSDLTSYLGSSSSGGRTHRTGQTRGTRTTRHSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDB1</accession>
    <name>E3QDB1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">60s Acidic ribosomal protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_04027</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">P1 and P2 exist as dimers at the large ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein P1/P2 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092903.1">
        <property type="nucleotide sequence ID" value="XM_008094712.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDB1"/>
    <dbReference type="STRING" id="645133.E3QDB1"/>
    <dbReference type="GeneID" id="24409392"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04027"/>
    <dbReference type="eggNOG" id="KOG3449">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114656_0_2_1"/>
    <dbReference type="OrthoDB" id="1227494at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002182">
        <property type="term" value="P:cytoplasmic translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05833">
        <property type="entry name" value="Ribosomal_P2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.1410:FF:000002">
        <property type="entry name" value="60S acidic ribosomal protein P2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01478">
        <property type="entry name" value="Ribosomal_L12_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038716">
        <property type="entry name" value="P1/P2_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027534">
        <property type="entry name" value="Ribosomal_P1/P2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001859">
        <property type="entry name" value="Ribosomal_P1/P2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044076">
        <property type="entry name" value="Ribosomal_P2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21141">
        <property type="entry name" value="60S ACIDIC RIBOSOMAL PROTEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21141:SF5">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN P2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00428">
        <property type="entry name" value="Ribosomal_60s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00456">
        <property type="entry name" value="RIBOSOMALP2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="59"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="73"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ28883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="110" mass="10975" checksum="0775585B6DBA0C8A" modified="2011-01-11" version="1">MKHLAAYLLLGLGGNTSPSASDVKAVLESVGIEADDERLNKLISELEGKDINELISEGSGKLASVPSGGAGGAAPAAGGAAAASADAPAEEAKEEEKEESDDDMGFGLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDF4</accession>
    <name>E3QDF4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_04070</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092946.1">
        <property type="nucleotide sequence ID" value="XM_008094755.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDF4"/>
    <dbReference type="GeneID" id="24409435"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04070"/>
    <dbReference type="eggNOG" id="ENOG502SUJA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031212_0_0_1"/>
    <dbReference type="OrthoDB" id="5345571at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057082">
        <property type="entry name" value="PH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057081">
        <property type="entry name" value="PH_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23076">
        <property type="entry name" value="PH_FT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23074">
        <property type="entry name" value="PH_FT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="1">
        <location>
            <begin position="230"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="350"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ28926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="479" mass="55436" checksum="682B1AEBBB28A931" modified="2011-01-11" version="1">MEQSLQKIDYRLLQGCCLEAERADIVSVSLEGLRMALPESYGGPINALVAGMRKCARLLRDLADLSQMHFNRVPILLNYLQIILPCLSRTLRDITEYYEDRTVSKDIRWRRMYHKMTQEVGALPLPQRFVLYNHFLDCLKQLLIRSPTFDLNGLELLRTRIIEMREARGLPTPAHVGPVVRPETLLMPITQDPTIHWAEQIFSLPLPSRTALKHTKTSKACGPFQAWGQLNIPKETKMLFRRPFDEDRLALMAYLNLVNHTPYILLRTYHLGAPWFSLRGTHELVLQREENCLQLKRWSISQGAPKLWASLYFKTWEELTLFHCTFVSLKARNTMTTNMQPREFKLAGEKKTFQAQIIDDGFKHSLMVYQDIATRGFRLHAAVWDGELRLCPVWTAFVTHQSASPTWLRRKSPHCVWLKDVQLYVFCKGYRQQNQRKGEAGAFEINFVSEDGAAHFHEAFSSTVSEPSTDSREAIEDSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QE94</accession>
    <name>E3QE94_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04326</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093202.1">
        <property type="nucleotide sequence ID" value="XM_008095011.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QE94"/>
    <dbReference type="GeneID" id="24409691"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04326"/>
    <dbReference type="eggNOG" id="ENOG502T4A5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_842006_0_0_1"/>
    <dbReference type="OrthoDB" id="4755921at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="330" mass="35738" checksum="671932D62A8A7ED4" modified="2011-01-11" version="1">MARKPNENRPRKDSGDSGVSGDSGDSGDSGVDVRSSVKAQTLNPMAKEFSFIVPKQDPIKVESPEETSISIPLSMLKKILGSSSPSNIIDAPPQSLDEIIANTIQRFGIPEVRPQYMSLPDPFSTLVMSPTLQPPFVQHTTSPPISPTFGLHNNSMTSPFGMFSQMPGAPLNPSAAGFVPFVPPSKAGIPPRLPPFGSQPNLPASVQPPSRYVPQMKSCYMPAPDYGRQMANGPSMPGSGFIPHLNSCFLPEQPSMPNQGNFLNSNTAPSSVPCIGPRPARKPRVPDAFAQQNYEAYIEWRKANEPGYAHECKDRQSRRAKRLKGADPYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEM0</accession>
    <name>E3QEM0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_04470</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093346.1">
        <property type="nucleotide sequence ID" value="XM_008095155.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEM0"/>
    <dbReference type="STRING" id="645133.E3QEM0"/>
    <dbReference type="GeneID" id="24409835"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04470"/>
    <dbReference type="eggNOG" id="KOG0156">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_2_1_1"/>
    <dbReference type="OrthoDB" id="1103324at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF5">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="432"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ29326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="531" mass="60238" checksum="0AFB203F54D493C3" modified="2011-01-11" version="1">MILPLNDNLARLQQEYSGAITTVLAVTVLVIAAVSLQEYFRPVGNLLQATDAKGDPFNRYLHSLSQYGEMATLHLGSKTWVFLNSSRVVSEIIAKRSSQTNTRAPMPISNTLVGRGLKSLVLPQELWTEPRRVMHSLLSGTALRQYGEWQELESTQMMAEYVIRPGAWYRHHYRYANSVIHRIALGERMVKTPEELVEMQNAVTFFVGSIGTSIVDWFPDLARLPRFLQIWRPHWKEVGDWNYDLYSRWYNPVKEKVENGTAPPSFVRDVLLNPDTRYKGSHEEGMYVAMSLVEAGSDTTREALNIMTMAALEYLDVFVKARDEVDSVCGVGEHARLPTLADMDELRYICAMAKEVLRWRPIFPLTPDHTATQDIEFEGYYFPAGTGFTINGPVVSYECEAPEDFVPERWLDGHETDIAHGLWAFGGGRRICVGYRLAQRSLFLNIARLAQCVDYKPNGPYNSHILNLDVAGEPFPVKVTMRSPACEALILREAEAAGVLEHAKLFRDEDEARVELGSGRCRFTNRLFKHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEQ4</accession>
    <name>E3QEQ4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">14-3-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_04504</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 14-3-3 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093380.1">
        <property type="nucleotide sequence ID" value="XM_008095189.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEQ4"/>
    <dbReference type="STRING" id="645133.E3QEQ4"/>
    <dbReference type="GeneID" id="24409869"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04504"/>
    <dbReference type="eggNOG" id="KOG0841">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058290_0_0_1"/>
    <dbReference type="OrthoDB" id="10260625at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.190.20:FF:000001">
        <property type="entry name" value="14-3-3 gamma 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.190.20">
        <property type="entry name" value="14-3-3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000308">
        <property type="entry name" value="14-3-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023409">
        <property type="entry name" value="14-3-3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036815">
        <property type="entry name" value="14-3-3_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023410">
        <property type="entry name" value="14-3-3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18860">
        <property type="entry name" value="14-3-3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00244">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000868">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00305">
        <property type="entry name" value="1433ZETA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00101">
        <property type="entry name" value="14_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48445">
        <property type="entry name" value="14-3-3 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00796">
        <property type="entry name" value="1433_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="14-3-3" evidence="4">
        <location>
            <begin position="1"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="211"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="211"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="228"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with phosphoserine on interacting protein" evidence="2">
        <location>
            <position position="35"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with phosphoserine on interacting protein" evidence="2">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000868-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ29360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="250" mass="27618" checksum="80F2B20105939FF8" modified="2011-01-11" version="1">MVGYMKEVAKLGGELSVDERNLLSVAYKNVVGTRRASWRIISSIEQKEESKGSDKHVGTIREYRTKIETELEQVCQDVLDVLDDSLIPNAQTGESKVFYHKMKGDYHRYLAEFASGEKRKGAATAAHEAYKSATDVAQTELTPTHPIRLGLALNFSVFYYEILNSPDRACHLAKQAFDDAIAELDSLSEESYRDSTLIMQLLRDNLTLWTSSDSGDAEGAAAGTAEASEEKKEEAKTEEPKAAEETPAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFG2</accession>
    <name>E3QFG2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Ribosomal protein/NADH dehydrogenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_04744</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the complex I NDUFA2 subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093620.1">
        <property type="nucleotide sequence ID" value="XM_008095429.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFG2"/>
    <dbReference type="STRING" id="645133.E3QFG2"/>
    <dbReference type="GeneID" id="24410109"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04744"/>
    <dbReference type="eggNOG" id="KOG3446">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110897_1_1_1"/>
    <dbReference type="OrthoDB" id="10250268at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000219">
        <property type="entry name" value="NADH-ubiquinone oxidoreductase 10.5 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016464">
        <property type="entry name" value="NADH_Ub_cplx-1_asu_su-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007741">
        <property type="entry name" value="Ribosomal_mL43/mS25/NADH_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12878:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12878">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE B8 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05047">
        <property type="entry name" value="L51_S25_CI-B8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005822">
        <property type="entry name" value="NDUA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00916">
        <property type="entry name" value="L51_S25_CI-B8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Ribosomal protein/NADH dehydrogenase" evidence="10">
        <location>
            <begin position="20"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ29600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="94" mass="10433" checksum="3F8F17C2DE8C692E" modified="2011-01-11" version="1">MSGKYAFTKALKEVRFLFCQTGEHSAATRSFVARAYPTMKKNNPQTPILLREAAGTLPKVYARYEFGVEKSQSLEGLSDKQIEDTVTTLVKNGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGA9</accession>
    <name>E3QGA9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04849</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093725.1">
        <property type="nucleotide sequence ID" value="XM_008095534.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGA9"/>
    <dbReference type="GeneID" id="24410214"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04849"/>
    <dbReference type="HOGENOM" id="CLU_2687680_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="74" mass="8539" checksum="54AA12026D303A29" modified="2011-01-11" version="1">MPGDNSRPEEKEEKDHGHPRLPRLADISTLSTFLFRGDTWEAIVNVVNVVTEQNRTEQSRDWEKEEGAIQSTYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHA3</accession>
    <name>E3QHA3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_05409</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPL family. K-HECT subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="3"/>
    <dbReference type="EMBL" id="GG697348">
        <property type="protein sequence ID" value="EFQ30265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094285.1">
        <property type="nucleotide sequence ID" value="XM_008096094.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QHA3"/>
    <dbReference type="GeneID" id="24410774"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05409"/>
    <dbReference type="eggNOG" id="KOG0168">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0170">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000366_1_1_1"/>
    <dbReference type="OrthoDB" id="423283at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016607">
        <property type="term" value="C:nuclear speck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045322">
        <property type="entry name" value="HECTD1/TRIP12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057948">
        <property type="entry name" value="TPR_TRIP12_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45670:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE HECTD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45670">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE TRIP12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25579">
        <property type="entry name" value="TPR_TRIP12_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="8">
        <location>
            <begin position="1355"/>
            <end position="1713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="554"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="911"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1044"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1149"/>
            <end position="1181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="24"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="54"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="570"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="590"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="625"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="968"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1075"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="6">
        <location>
            <position position="1680"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ30265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1713" mass="187593" checksum="4E527D9F4BB8B6B0" modified="2011-01-11" version="1">MTGTDDTEKDPIPPPPPPPPEHHDDDDDDDDSDENDDDDEDGRRYDDEDDDPFGGFGGPGGPGGLSSTLRALTGMMSGISSRLRELLNNLRQKNDPSIQLIALQELSEILLVSNEDNLSGHFSPDSFVKELVTLMQPNEITGEENPEIMLLACRCLANLMEALPASVANVVYGGAVPVLCQKLLEISFIDLAEQALSTLEKISAEYPSSIVREGGLTACLSYLDFFATSTQRTAVTTAANCCRNIPEDSFPVIRDVMPTLLNVLGSSDQRVVEQASICVSGIVESFKYQSAKLEELVSVDLLKAVLRLLVPGTTNLIRSDIHTQFLRVLAFTARASPQLSAELFKLNIVETLYQILTGVSPPSGTEDVASKLDSVVIMQALIHRPKEQIIETLNVICELLPSLPRNADPSYGDFVEMNSTEPITPSSTAPGKARKSPNDKRIELLDGCKAEVRRFALILFPTLTDAFSSTVNLNVRQKVLTAQLKMLSNLNEEILGEALKTVSYASFLASILSQQDHPSLVMLALQATELLLSRLEDVYRYQLYREGVISEITKLATEEQTPPPATEPTGSQETSNTDPQASADSGEPSSDNEESEDDEDHEESEDEENEEENEHEHHPDDITGSPVSSRGSTMSLDGPPQHLLSDVPSMLSRIREVAKKFLESHETEKHGKTMKKKALKILSNLSDLAEEIEAFYLRRTATNLAPENGVELFKKLASSFDADVLESVTSAELLASGLVRVLLEVFSNPDEELARTAQSAFLQVFMGYSVKSRPKTATADSPATPFSVMVHKLQDLLSRSEHFEVITVHQNTFDGNRSSAASMLAKQIRLRLVADDDSDIPRSYRNIMVSIHAIATFKSLDDYLRPRISLSERPRGSRRADNLSRALASLAGSAGLPLSHAAARLAERASAASASSPIPPPPNAATSSGSRSLRKTKTKSTPPSEAAASPDTSSTTRDKGVLRRSARRSAASTTESPAPSRPPPEEDDLENALECADEKHLSDDEEIGGSSALDAIVGDLDEDMSESPGPEPGAVNMEIAAGGRVTARKEDGTRVPTPSQSALPTRSGALPPPQSQSTPTPSTSSSRPMTYAAAIQTVPQDWHIEFTLDGKVISSETTIYRAVHTSAANSDEHFSRSVWSAVHPIKFRRAPGPPPVETLSFSSNAEASTEDNGDGNVPASLAKHPSTASILRLLNILHDLNANIDDVMVENSEKDAVRLNVEPLSQFVNTKLTAKLNRQLEEPLIVASNCLPSWVEDLARLYPFLFPFETRHLFLQSTSFGYARSMTRWQNAQAADDSRRDRRDDRPFLGRLQRQKVRISRSKILESALKVMELYGASQSILEVEYFEEVGTGLGPTLEFYSTVSKEFSKKKLKLWREMDSNDSEEYISGASGLFPRPLSDDEASAPNGERILQLFRTLGKFVARSMIDSRIIDLNFNPTFFRIGDGSSAPGVKPSLGAVKVVDPGLARSLKTIKKFAVAKKEIDEDPSRTPAQKVADTEDIAIDGMKLDDLCLDFTLPGYPEIELIPNGGQIRVTIDNVDSYLERVVDMTLGTGVRRQVDAFRTGFSQVFPYSALSAFTPDELVTLFGRVEEDWSLETLMDSIKADHGYNMDSKSVKNLLQTMSELSPPERRDFLQFTTGSPKLPIGGFKSLTPMFTVVCKPSEHPYMSDDYLPSVMTCVNYLKLPDYTSIEVMRKQLSTAIKEGQGAFHLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHQ7</accession>
    <name>E3QHQ7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">alpha-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_05539</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing (1-&gt;4)-linked alpha-D-glucose residues with release of alpha-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.20"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.20" evidence="3"/>
    <dbReference type="EMBL" id="GG697349">
        <property type="protein sequence ID" value="EFQ30395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094415.1">
        <property type="nucleotide sequence ID" value="XM_008096224.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHQ7"/>
    <dbReference type="STRING" id="645133.E3QHQ7"/>
    <dbReference type="GeneID" id="24410904"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05539"/>
    <dbReference type="eggNOG" id="KOG1066">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000631_9_0_1"/>
    <dbReference type="OrthoDB" id="1334205at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004558">
        <property type="term" value="F:alpha-1,4-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14752">
        <property type="entry name" value="GH31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1760">
        <property type="entry name" value="glycosyl hydrolase (family 31)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025887">
        <property type="entry name" value="Glyco_hydro_31_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762">
        <property type="entry name" value="ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762:SF165">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G06560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13802">
        <property type="entry name" value="Gal_mutarotas_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 31 N-terminal" evidence="7">
        <location>
            <begin position="39"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="6">
        <location>
            <begin position="262"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="8">
        <location>
            <begin position="625"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="55"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ30395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="876" mass="96396" checksum="34F73599CC9C1F3F" modified="2011-01-11" version="1">MLLQNERIPTKYAPKGAKGAASNASIQLQSSEGQTEPFTFTFEVVRSTVFRTTVTSKSRPLPPFPSAHKPSPGSAPKDVDVKTSEGTQTFTTSAAKAVVEWTGDTPIVSLYAGQDAAGKPIHADLPFRSYAADGPGIAHYSVYKKGTLHVGLGEKAAPMDLSGRGFIISASDTFGYDAYRTDPLYKHIPLLINVTPEGAVGIFSTAHSRSTWSIGSELDGMWGAYKVHRQSHGGLEEYLIVGKTVAEVVHSYAELVGFPLRVPRYMMGYIGGGMKYSAMDSPRAHDAIMGWVKQCEKHDIPFSAFQMSSGYTVAETEPKTRNVFTWNYHRFPDPRAFTREAHSHGLRLLANVKPYVLATHPEYKKLSAAGAFFKDPNTGKTAVTRLWSAGGGESGEGSHLDFTSNAGYQWWYDGVVGLKKVGIDVMWNDNNEYTVPDDEWQCALEKTDLVPIPEGLSRKDVGIWGRAIHTELMGKASHDATIEGKPEERPFVLTRSATAGTMRYCGASWSGDNVTAWESMRGGNSLALNASFSLLHCYGHDIGGFEGPQPTPEHLVRWIQLGVHSPRFAINCFKTSEEDNLIGGVIEPWMYPTATPIIRATIKRRYELVPYTYSQNLRAHHTAVPPQRWTGWGYESDPEVWTKEIKNGDTQYWFGDAFVIGGVYEPGVDTAKVYLPKKGDGSDYGFLNTNAPYEHFEAGKWQTVLSPWYTSIPIIARVGAAVPVGKPLDTTSRKEDDPEFPNQAKDDWRGVEIFPPPALRGAAAKGVQTEPAADDDVKGVVFEDAWYEDDGISREVAAEFKFTIRYEIVDDAISVDVKAAVTEGSKEGWSPLWLDKGIDVLLPVGEERRVISKAGEATEKALDARGRRTWNVPVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHT3</accession>
    <name>E3QHT3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_05565</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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    </dbReference>
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    <dbReference type="GeneID" id="24410930"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05565"/>
    <dbReference type="eggNOG" id="ENOG502RR4N">
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    </dbReference>
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    <dbReference type="OrthoDB" id="5199007at2759"/>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ30421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="211" mass="23007" checksum="6866578865A4B57C" modified="2011-01-11" version="1">MSSATCKKSIDSTMSHFTVGMGKASVQNNVSLWTTLSQCYDEVAKTFALQDPEGVLSAPDSISKVVHATFDHDEHGLIEQGSSAMANHLDDAAKAHMLAQAVAGTVAFFRRLASSHRRGPVTQAGFDREVRRFAECGLRSAMIRKIDESRLFGRCYTKSQIADLILDAVEGNVSDAEFASEDEYQNAIGWATELPARNMGLPWGFTIMAIN</sequence>
</entry>
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    <accession>E3QI17</accession>
    <name>E3QI17_COLGM</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_05649</name>
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    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
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            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
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            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697349">
        <property type="protein sequence ID" value="EFQ30505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094525.1">
        <property type="nucleotide sequence ID" value="XM_008096334.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QI17"/>
    <dbReference type="GeneID" id="24411014"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05649"/>
    <dbReference type="HOGENOM" id="CLU_2223085_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ30505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="106" mass="11928" checksum="D827BA5250E7DB28" modified="2011-01-11" version="1">MLQRHKAHLRRRLEPRGNFSHLGGISYQRTVSGKLVALAWMVDCSQISCYRSIALFAGLGHKRALPLCISCGRRRVPRPHVQRQLVGGSRHEVPDLASLQLGCHRP</sequence>
</entry>
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    <accession>E3QIY3</accession>
    <name>E3QIY3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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        <name evidence="2" type="ORF">GLRG_05965</name>
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        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
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                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="STRING" id="645133.E3QIY3"/>
    <dbReference type="GeneID" id="24411330"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05965"/>
    <dbReference type="eggNOG" id="ENOG502TFDF">
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    <dbReference type="OrthoDB" id="5376010at2759"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
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            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
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            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="120" mass="13540" checksum="F8473626A8E93B90" modified="2011-01-11" version="1">MGEDRRDVLGAQRMPGQMRWAPGTGRVCDPGHPRELWKSVFGGDDGRPALLRMAHEERAVGDGGEASVRMVDVEEKGWKGRSEVLVVDKNGVRRKHTIEPRRLLGQQPHSRQVKRHKPGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
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            <fullName evidence="1">Uncharacterized protein</fullName>
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    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
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                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
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            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697351">
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    </dbReference>
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    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06037"/>
    <dbReference type="HOGENOM" id="CLU_2413134_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ30893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="92" mass="10057" checksum="A35C84A938B4FD11" modified="2011-01-11" version="1">MSASKLVSAQALAAGNGHEHQYRPSFGVAELVHDLRNRVLGALRMLGYEMEDAIEGDHADTLDNQGVNVRKEQPDAMLIEVRVRCPGRETGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJ90</accession>
    <name>E3QJ90_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tafazzin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_06072</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ30928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094948.1">
        <property type="nucleotide sequence ID" value="XM_008096757.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJ90"/>
    <dbReference type="STRING" id="645133.E3QJ90"/>
    <dbReference type="GeneID" id="24411437"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06072"/>
    <dbReference type="eggNOG" id="ENOG502S698">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032824_1_0_1"/>
    <dbReference type="OrthoDB" id="5278911at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="484" mass="52639" checksum="3E0BAF7E6BCB8053" modified="2011-01-11" version="1">MPKKRHQALYSKPQSTAPSSLGASASASSSSQSQRKGVNELLADLRRSSPRATSTASAAVSEATAPTVPPALRQILQIPETPPPPPRRAPRFDATGRRVPPGPPPPRSWLSRTSSHAQRAHATAAQRGAQAIQGLPGTYEPDKGSLMDIVLRRMALNWELQRDYDQYYLHMLPSRARASLAKYVGIWYEGGVSAADLRNILIPPPPPPASRYDDGSEHQQPQVEAEALVSLNSNIYSLDLTGSVGHSMSVRELSDVLFPPKLARASEVVQDSWDTAEAPSLPPKLLPNITHLCLAVAPSVYQQGGGPGVSWRQLLALAAKLPTLTHLSLAYWPEPSMTPNAKFTTIVSPEGVVQQYSGTGAYAHTLDNDWSEAVILLRKLSKCLYGLEYLDLTGCGAWFKALMANVDGDKVDWGGPWGKVSTLKLRYGYDVSKDTPIVDSERYRAAAEMARSVEKYIVAQRAGKGRFINVDSDAIDDAWWPSMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJD4</accession>
    <name>E3QJD4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase</fullName>
            <ecNumber evidence="5">2.7.8.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">GlcNAc-1-P transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">N-acetylglucosamine-1-phosphate transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">GLRG_06116</name>
    </gene>
    <organism evidence="21">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis, transfering GlcNAc-1-P from cytosolic UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol embedded in the cytoplasmic leaflet of the endoplasmic reticulum membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>a di-trans,poly-cis-dolichyl phosphate + UDP-N-acetyl-alpha-D-glucosamine = an N-acetyl-alpha-D-glucosaminyl-diphospho-di-trans,poly-cis-dolichol + UMP</text>
            <dbReference type="Rhea" id="RHEA:13289"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19507"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58427"/>
            <dbReference type="EC" id="2.7.8.15"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="18">
            <dbReference type="Rhea" id="RHEA:13290"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyltransferase 4 family.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.15" evidence="5"/>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ30972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094992.1">
        <property type="nucleotide sequence ID" value="XM_008096801.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJD4"/>
    <dbReference type="STRING" id="645133.E3QJD4"/>
    <dbReference type="GeneID" id="24411481"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06116"/>
    <dbReference type="eggNOG" id="KOG2788">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029942_1_0_1"/>
    <dbReference type="OrthoDB" id="10262326at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043541">
        <property type="term" value="C:UDP-N-acetylglucosamine transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003975">
        <property type="term" value="F:UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009060">
        <property type="term" value="P:aerobic respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd06855">
        <property type="entry name" value="GT_GPT_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033895">
        <property type="entry name" value="GPT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10571">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10571:SF0">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 19" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="179"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="310"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="435"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00029567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00033238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00045078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EFQ30972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="474" mass="52977" checksum="1934C9B654502408" modified="2011-01-11" version="1">MSSSTTTSAAAAALTRNETLSLGALSFAAVAVLLNTFQGDGEPLIASLALSVLAFALAYSMIRWLGPVFKRAGFRGRDLSKHHRPELPECMGAVCAAVYLLVVIVFIPFPFYKDIVAATSGGGNRDVVYHLEHVQQGRFLHRFPHSKLASYLSAIISLQTIALLGIGDDLFDIRWRHKWWIPGLASVPILVIYFVDFGVTSIVIPIPLQPYLGELFDLGVLYYAYMACIAMFCPQSINMLAGINGIEVSQCIVVSLLLVLNDCLYLLTPYPHPATDSHLFSLFLLLPWLGVSLALVLHNWYPAKVFVGDTYCYFSGMVFATVGILGHFSKTLGLLLVPQLFNFLYSTPQIFGLVPCPRHRLPRFVARTGLLEPSVTPWSPERQPHPLVARALHLLARLRLLSVTTDDKGRFVETSNLTLLNLWLVWRGPLREDRLAWEVTFLQLFVGLFGLFVRHRLALLIFKEDNWGMTTKRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJT7</accession>
    <name>E3QJT7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_06269</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697353">
        <property type="protein sequence ID" value="EFQ31125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095145.1">
        <property type="nucleotide sequence ID" value="XM_008096954.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJT7"/>
    <dbReference type="GeneID" id="24411634"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06269"/>
    <dbReference type="eggNOG" id="ENOG502T6HM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_158763_0_0_1"/>
    <dbReference type="OrthoDB" id="3523319at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ31125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="106" mass="11182" checksum="1BD7D82E0BE9C44F" modified="2011-01-11" version="1">MAAVYTGPSVADMLANRTLAKEIIARNSDPEPILDADELALLEQFVNDPNRANAILESKGLAADPKNLGSLVAYVISLHATDSPALSAEDISSLKAWYANNAGEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QK10</accession>
    <name>E3QK10_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Sodium/calcium exchanger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_06342</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.</text>
    </comment>
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        <property type="protein sequence ID" value="EFQ31198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008097027.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QK10"/>
    <dbReference type="STRING" id="645133.E3QK10"/>
    <dbReference type="GeneID" id="24411707"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06342"/>
    <dbReference type="eggNOG" id="KOG1397">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001583_0_0_1"/>
    <dbReference type="OrthoDB" id="16982at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990816">
        <property type="term" value="C:vacuole-mitochondrion membrane contact site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015369">
        <property type="term" value="F:calcium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015386">
        <property type="term" value="F:potassium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015385">
        <property type="term" value="F:sodium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1420.30:FF:000017">
        <property type="entry name" value="Calcium permease family membrane transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="entry name" value="NCX, central ion-binding region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004713">
        <property type="entry name" value="CaH_exchang"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005185">
        <property type="entry name" value="YccF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503:SF10">
        <property type="entry name" value="VNX1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03733">
        <property type="entry name" value="YccF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="281"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="524"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="556"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="588"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="624"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="656"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="732"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="947"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1018"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1051"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1081"/>
            <end position="1100"/>
        </location>
    </feature>
    <feature type="domain" description="Inner membrane component" evidence="11">
        <location>
            <begin position="284"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="10">
        <location>
            <begin position="558"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="10">
        <location>
            <begin position="946"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="390"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="815"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="888"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="47"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="69"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="134"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="166"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="213"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="816"/>
            <end position="825"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ31198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1139" mass="125540" checksum="E9265D33FFEF06E0" modified="2011-01-11" version="1">MDPSTGPGAIAHEESHDSSAAASPTDTRHRPSRFDSYVASREDGLSESFQSFQSTDTVRRRPEGGYGSIHTQASGSQYPSESSAHDRSHSRSTQATRSPMMGPERPKASRPRKPPMPRRLSTNPSAPHRGEVFSADDDIYEVEADAAERHQGQRANIYGTRRRPQLPTTLSRVQSTHSENNEDEDDEDDGPRTPRADENVPEELERDPSVHPDEEDIGVESDGDVSDAESFTLKDRQQAINQTHPFGIRLWKPALYKKDRSVQKNAEGDIHSTPGGRVHSWLLFFNLLWTLLFGWWMAAFSALGAVVCFLFAATPSGREYGRVLWGLAAYLFYPFGKFVRLEQDEAYLHEDQGEGRSISEYEQWQNGDLEYGRLFFGPEGFERTRSIVGRSRRSIDSEPSETDSLLGRSRRGDRSQTPPQTKRRLFGRGQWNIGRVVFFLFFYLLLSPSLILVSLICWFFVFSIPMGKVTMLLFDQLRRHPLALSFEADMVLSRTADTPQSSILLCTYRAVGIKYWKYTIDGTNVFLINLMGVVFFVIFDWLVLDNVLHLDLFITSPAFLFITGLFSIVPLAYFIGQAVASISAQSSMGVGAAINAFFSTIVEVFLYCVALSQGKGHLVEGSIVGSIFAGILFLPGLSMCFGAIKRKTQRFNARSAGVTSTMLLFAVLGAFGPTLFYQIYGTHELNCLDCVSHSGIGGGLSPVGDGRDCKRCFFSQTPALNDRFYLEAVRPFCYFCATLLFLSYIVGLWFTLRTHAAVIWNSEIDEKKHEEAHAHARQSVPHSFAETTGTSVDVRDSHLYKRILGQSLKQVGLAAKGDDASRHDSTTGLGLAPGNGGVSIPHVVPPKSSSSETVRSTVHIPGFSEAENNALVREVAEMAATAATIAARERMPRRTSAQPGSLGANLPRTPALRTAAVPEAEDLAAASTVQVPHGGHDAPNWSRGKSAIILMGATVLYAIIAEILVDTVDVVLEGFAIDEKFLGITLFALVPNTTEFLNAISFAMNGNIALSMEIGSAYALQVCLLQIPALVFYSAFWATTEGVEDVSARTFALLFPQWDMVTVIICVFLLSYMYGEGKSNYFKGSILLLSYLVVVVGYYLSGFTEDGMSMNRFDVMGVDGQYSSYKTVGRRLNGAVLQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKA6</accession>
    <name>E3QKA6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">non-reducing end alpha-L-arabinofuranosidase</fullName>
            <ecNumber evidence="4">3.2.1.55</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_06438</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides.</text>
            <dbReference type="EC" id="3.2.1.55"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycan metabolism; L-arabinan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 51 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.55" evidence="4"/>
    <dbReference type="EMBL" id="GG697354">
        <property type="protein sequence ID" value="EFQ31294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095314.1">
        <property type="nucleotide sequence ID" value="XM_008097123.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKA6"/>
    <dbReference type="STRING" id="645133.E3QKA6"/>
    <dbReference type="GeneID" id="24411803"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06438"/>
    <dbReference type="eggNOG" id="ENOG502QQEX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010060_1_1_1"/>
    <dbReference type="OrthoDB" id="406864at2759"/>
    <dbReference type="UniPathway" id="UPA00667"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046556">
        <property type="term" value="F:alpha-L-arabinofuranosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031222">
        <property type="term" value="P:arabinan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046373">
        <property type="term" value="P:L-arabinose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010720">
        <property type="entry name" value="Alpha-L-AF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055235">
        <property type="entry name" value="ASD1_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051563">
        <property type="entry name" value="Glycosyl_Hydrolase_51"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31776">
        <property type="entry name" value="ALPHA-L-ARABINOFURANOSIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31776:SF0">
        <property type="entry name" value="ALPHA-L-ARABINOFURANOSIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06964">
        <property type="entry name" value="Alpha-L-AF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22848">
        <property type="entry name" value="ASD1_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00813">
        <property type="entry name" value="Alpha-L-AF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178571" description="non-reducing end alpha-L-arabinofuranosidase" evidence="8">
        <location>
            <begin position="20"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-L-arabinofuranosidase C-terminal" evidence="9">
        <location>
            <begin position="466"/>
            <end position="639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ31294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="663" mass="71615" checksum="61D2E5DBCACD4747" modified="2011-01-11" version="1">MVSLKSAFLAATYAVSAAAVDITVKSSGGNATSGHQYGFLHEDINNSGDGGIYAELIRNRAFQYSDEFPVSLAAWHPVNGAKLALKNLAQPLSSALPVSVQVSGGNSSGAIGLKNDGYWGMDVKVQKYTGSFWVKGAYDGVFTASLQSALTDDVFGSVEIQSKAKADEWVEHEVELVPEKNAPNSNNTFAITFDPAGTANGSLNFNLISLFPPTYKGRKNGLRIDIAEALAGLHPSLLRFPGGNMLEGLNNKTYWDWKDTLGPLKDRPGFQGVWGYQQTHGLGLVEYLEWAQDMNLDVVIGVWAGLALNGDVTAKEDLQPFIDDALDQIEFIRGPADSKWGARRAELGHPEPFTLEYVEVGNEDWLAGYPGGWESYKEYRFPMFMEAILAKYPDITVISSGATSDADGYDIPPPAIGDYHPYRTPDALVDEFDRFDNDIGHIVGEVAATHPNGGIGWEGNLMPFPWWIGTVGEAVSLIGYERNADRIPGTFYAPVLRNMNRWQWAVTIVQFAADPAITTRSTSWFVWELFAAHPMSETLPTVGEFGPAYWVAGKNEAKGSLIWKGAVYNTTDSADVPINVRFEGVAAGTTASLTVLTNPGGDPYAYNDPLAGTNVVASNTTTVTANEDGVFAFSLPELSVALLDTEGSAGAKQAARAVKSFRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKQ0</accession>
    <name>E3QKQ0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoglycerate mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_06582</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697355">
        <property type="protein sequence ID" value="EFQ31438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095458.1">
        <property type="nucleotide sequence ID" value="XM_008097267.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKQ0"/>
    <dbReference type="GeneID" id="24411947"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06582"/>
    <dbReference type="eggNOG" id="KOG4754">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039184_0_1_1"/>
    <dbReference type="OrthoDB" id="496981at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF32">
        <property type="entry name" value="ANCHORED PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G10590)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180526" evidence="1">
        <location>
            <begin position="19"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="365" mass="40578" checksum="77DA6092FCA27763" modified="2011-01-11" version="1">MKGLMLSAVLAFAPTALAAWPQAEGKNIKFTSVPGYFLQDDASTNPTGFDYATVNFGLLNRTYPTDKHFDPEGVKTQWERFDHWVRYLNSGCGKSDSVQYKLLFMGRHGEGWHNAAESFYGTPAWNCYWAEQDGNGTARWADPLLTPAGEAEAYKANAYFKDRYATQKMPYFESYYTSPLIRCGYTANITFGDIGVPADKPLKPIVKEGFREGITVHTCNRRSDKTYIAETFPSFEFEAGFTEHDELWRRNESETEEAHAARSKAVLDDVFRTDDKTWLSITAHSGQITKLLASLNHRAFRLSTGQIIPVLVKAEIIEPQPDPTFEAYEPYSTCDAPPIASIAGLGCICATATSALLPAATHIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKQ6</accession>
    <name>E3QKQ6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PfkB family carbohydrate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_06588</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697355">
        <property type="protein sequence ID" value="EFQ31444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095464.1">
        <property type="nucleotide sequence ID" value="XM_008097273.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKQ6"/>
    <dbReference type="STRING" id="645133.E3QKQ6"/>
    <dbReference type="GeneID" id="24411953"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06588"/>
    <dbReference type="eggNOG" id="ENOG502S13D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032834_0_0_1"/>
    <dbReference type="OrthoDB" id="497927at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47098:SF1">
        <property type="entry name" value="PFKB FAMILY CARBOHYDRATE KINASE SUPERFAMILY (AFU_ORTHOLOGUE AFUA_4G09500)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47098">
        <property type="entry name" value="PROTEIN MAK32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="1">
        <location>
            <begin position="259"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="375" mass="39732" checksum="0124891351381445" modified="2011-01-11" version="1">MTAPRVPPDPLPAPPPAFVSLGMVVLDEIRFPDGRVLRDVPGGSGFYGTLGARLAVPQDESAAVCCLVTAGSDFPPSVRRQIEEWGVSMHMEQVPGARSTRGLLEYEDDAFGKKTFRYTTPPLHPTVDGLPASLLGSSVIHVLATPEDLERHVSALVARRAGADGPRPLVAWEPSPIGISDREDDHMRAAGLSDVCSPNDHELLRMMGVEEGPGIPYNRALVEAFAVRLARGGGGGGGGSGEDLLGGPSVPDTSDRGITVIRCGDQGCLTVRWGASPVWRPPFHDYGSPKVVDPTGAGNAFLGAFAVAFAKTGDDALASAWGAVAASFVIEQIGPPEREVVNGKEVWNGERFEDRLEKYKAKVATWPTSPSTRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKQ9</accession>
    <name>E3QKQ9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Importin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_06591</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697355">
        <property type="protein sequence ID" value="EFQ31447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095467.1">
        <property type="nucleotide sequence ID" value="XM_008097276.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKQ9"/>
    <dbReference type="STRING" id="645133.E3QKQ9"/>
    <dbReference type="GeneID" id="24411956"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06591"/>
    <dbReference type="eggNOG" id="KOG2171">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003794_1_1_1"/>
    <dbReference type="OrthoDB" id="7862313at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
        <property type="term" value="C:nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058584">
        <property type="entry name" value="IMB1_TNPO1-like_TPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040122">
        <property type="entry name" value="Importin_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034085">
        <property type="entry name" value="TOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057672">
        <property type="entry name" value="TPR_IPO4/5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10527">
        <property type="entry name" value="IMPORTIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25574">
        <property type="entry name" value="TPR_IMB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25780">
        <property type="entry name" value="TPR_IPO5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01349">
        <property type="entry name" value="TOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="9">
        <location>
            <begin position="24"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="8">
        <location>
            <begin position="386"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ31447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1070" mass="117173" checksum="7CEADB2F0821592D" modified="2011-01-11" version="1">MDKGNLVQLLQASQIPDTEKVKAVTAELQKNYYSQPESLLLLIEITISHDDAAIRQLASVQALRLTPRHWSKLAADKRELAKKHILESILNDQSASSRHSKSRLLACAVGLDLEDGEGQDFVRGVLSLNTSDNVAHREVGSYILFALLENDPTHFAEQTQQLLGLVQKTIVDPASADVRLASVKSVGALLMLVDPEEDTQSLNLIQQLVQPMVEILKNAISEGNDDQYRDVFEVFQSFLAYDSAFLAAHLKDLIHFMIDLAVNTEVEEDARSQALAFLSQCARYRRMKLQAMKDMGALLMVKSMQVVTEIDTDDEDDDNSPARTALSLIDQLASDLPPRQVIVPLLEQFTQFAQNPNPGHRKSAILSLGTAAEGAPDFIATQLQPLLPVVLQLLNDQDASVRHAALVGLIHLADEMADELSPQHRELISALLTNLEAVSGSSDKQGVRIIRAACGALDSLIGEGLDDELIKEFGPKLIVPMGKLLGHDDFAVKAAAAGAIGAIASALGGEQFKPYFKEVMGALGQYVTIKDSEEALALRSSVCDSMGRIADAVGAQEFQPYVMDLMKASEEALSLDNARLKETSFILWASLSKVYGSEFAHFLPGVFKGLFDCLELEEESVSIPGLKEEDIPEGLLLSGGKKLNFKAVDEDDEEDMDADWEDLDDFAGVTAVALEQEIALEVLGDVITHSCGADAIRQYLGDAMGKVAPLAEHPYDGARKAAISTLWRSYARVWQLFEESTGTKWQAGFPPKQQPDEVILNLGQMVVDATKGVWQEDTERSVVTEINRNVAATLKACGPSILTHEDLLKESITILGTLITRSHPCQQDLGDEEEEQEAEGSSEFDWLVIDTALDVVLGLATALGGDFAEMWKIFEKPILKFASSQEALERSTAVGVIAEAIKYMGEAVTPFTDSLLPVLAHRLTDPDPLAKSNAAYAIGQLIFNSQSTDKTIPQYPAVLEKLEPLLQVKESRMVDNVSGCISRMILRNPNPEFVERVLPAVVDVLPLQEDYEENAPIYQAIAKLYDQQNPTVGNLTPKILPILQSVLSPPEEQLEPETRQLVQKLVSLLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLA6</accession>
    <name>E3QLA6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">2-(3-amino-3-carboxypropyl)histidine synthase subunit 1</fullName>
            <ecNumber evidence="4">2.5.1.108</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Diphthamide biosynthesis protein 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Diphtheria toxin resistance protein 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">GLRG_06933</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-histidyl-[translation elongation factor 2] + S-adenosyl-L-methionine = 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + S-methyl-5'-thioadenosine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36783"/>
            <dbReference type="Rhea" id="RHEA-COMP:9748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9749"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:29979"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73995"/>
            <dbReference type="EC" id="2.5.1.108"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DPH1/DPH2 family. DPH1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.108" evidence="4"/>
    <dbReference type="EMBL" id="GG697356">
        <property type="protein sequence ID" value="EFQ31644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095664.1">
        <property type="nucleotide sequence ID" value="XM_008097473.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLA6"/>
    <dbReference type="STRING" id="645133.E3QLA6"/>
    <dbReference type="GeneID" id="24412298"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06933"/>
    <dbReference type="eggNOG" id="KOG2648">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037146_1_1_1"/>
    <dbReference type="OrthoDB" id="1649088at2759"/>
    <dbReference type="UniPathway" id="UPA00559"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120513">
        <property type="term" value="C:2-(3-amino-3-carboxypropyl)histidine synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090560">
        <property type="term" value="F:2-(3-amino-3-carboxypropyl)histidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11840:FF:000001">
        <property type="entry name" value="2-(3-amino-3-carboxypropyl)histidine synthase subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11850:FF:000001">
        <property type="entry name" value="2-(3-amino-3-carboxypropyl)histidine synthase subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11860:FF:000002">
        <property type="entry name" value="2-(3-amino-3-carboxypropyl)histidine synthase subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11840">
        <property type="entry name" value="Diphthamide synthesis DPH1/DPH2 domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11850">
        <property type="entry name" value="Diphthamide synthesis DPH1/DPH2 domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11860">
        <property type="entry name" value="Diphthamide synthesis DPH1/DPH2 domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016435">
        <property type="entry name" value="DPH1/DPH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042263">
        <property type="entry name" value="DPH1/DPH2_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042264">
        <property type="entry name" value="DPH1/DPH2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042265">
        <property type="entry name" value="DPH1/DPH2_3"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00322">
        <property type="entry name" value="diphth2_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10762:SF1">
        <property type="entry name" value="2-(3-AMINO-3-CARBOXYPROPYL)HISTIDINE SYNTHASE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10762">
        <property type="entry name" value="DIPHTHAMIDE BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01866">
        <property type="entry name" value="Diphthamide_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00032">
        <property type="entry name" value="Radical_SAM_3-amino-3-carboxyp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EFQ31644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="449" mass="49592" checksum="708D70F117319215" modified="2011-01-11" version="1">MEEDRAQTDLGIAADIEASHREEEAVTQPVMKQPKKRFVGRRTAAEAAARNGGSNGSIEDSNSIQVAQPKRGPRLLNQVPPDILNDPALKSAISILPSNYSFEIPKTIHRIRSSGAKKVALQMPEGLLLFATTISDILTEFCPGIETLIMGDVTYGACCIDDYTARAMGCDLLVHYAHSCLIPVDVTKIKTLYVFVDISIDTSHLLASLERNFASGKTIAIVGTIQFNATIHGVRGTLEKAGFKVLVPQIAPLSKGEILGCTSPQLKDDDKVDMILYLGDGRFHLESIMIHNPSIPAYRYDPYSRKLTRETYGHDEMQDLRRTAIRTAKTARKWGLILGSLGRQGNPHTMGLIEKRLKERGIPWVNLLLSEIFPGKLAMMGDVECWVQVACPRLSIDWGYAFPRPLLTPYEALVALEVRDDWGKGVYPMDYYGKDGLGRTKPAQLEANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLR0</accession>
    <name>E3QLR0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Mitogen-activated protein kinase</fullName>
            <ecNumber evidence="3 12">2.7.11.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_06773</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16 12">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="12">Activated by threonine and tyrosine phosphorylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.24" evidence="3 12"/>
    <dbReference type="EMBL" id="GG697357">
        <property type="protein sequence ID" value="EFQ31798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095818.1">
        <property type="nucleotide sequence ID" value="XM_008097627.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLR0"/>
    <dbReference type="STRING" id="645133.E3QLR0"/>
    <dbReference type="GeneID" id="24412138"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06773"/>
    <dbReference type="eggNOG" id="KOG0660">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_181_1_1"/>
    <dbReference type="OrthoDB" id="192887at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004707">
        <property type="term" value="F:MAP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0075018">
        <property type="term" value="P:positive regulation of appressorium formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07849">
        <property type="entry name" value="STKc_ERK1_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000040">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000073">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003527">
        <property type="entry name" value="MAP_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01351">
        <property type="entry name" value="MAPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="23"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ31798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="355" mass="41152" checksum="8B58B4F7C33EE520" modified="2011-01-11" version="1">MSRANPPNASGSRKISFNVSEQYDIQDVVGEGAYGVVCSAIHKPSGQKVAIKKITPFDHSMFCLRTLREMKLLRYFNHENIISILDIQKPRSYETFNEVYLIQELMETDMHRVIRTQDLSDDHCQYFIYQTLRALKAMHSANVLHRDLKPSNLLLNANCDLKVCDFGLARSAASQEDNSGFMTEYVATRWYRAPEIMLTFKEYTKAIDVWSVGCILAEMLSGKPLFPGKDYHHQLTLILDVLGTPTMEDYYGIKSRRAREYIRSLPFKKKVPFRTLFPKTSDLALDLLEKLLAFNPVKRITVEDALKHPYLEPYHDPDDEPTAPPIPEEFFDFDKHKDNLSKEQLKQLIYQEIMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLU4</accession>
    <name>E3QLU4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">HIG1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_06976</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Associates with the respiratory chain complex III/complex IV supercomplex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RCF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095852.1">
        <property type="nucleotide sequence ID" value="XM_008097661.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLU4"/>
    <dbReference type="STRING" id="645133.E3QLU4"/>
    <dbReference type="GeneID" id="24412341"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06976"/>
    <dbReference type="eggNOG" id="KOG4431">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087356_0_0_1"/>
    <dbReference type="OrthoDB" id="6604018at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097250">
        <property type="term" value="P:mitochondrial respirasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007667">
        <property type="entry name" value="Hypoxia_induced_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050355">
        <property type="entry name" value="RCF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12297:SF3">
        <property type="entry name" value="HIG1 DOMAIN FAMILY MEMBER 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12297">
        <property type="entry name" value="HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04588">
        <property type="entry name" value="HIG_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51503">
        <property type="entry name" value="HIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="HIG1" evidence="12">
        <location>
            <begin position="15"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="147"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="111"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="169"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="179"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ31832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="230" mass="25262" checksum="E48F84910FBF492C" modified="2011-01-11" version="1">MSGPDGKPTLLDRPMPSSFDENNEFYDERVLHKVFRKLREEPLVPLGCGLTVFAFVSAWRAIRRGDSVQANKMFRARVAAQGFTVLAMLAGSMYYNKDRERTAELRKIKEAKDAEEKRQRWIRELEARDDEEKALKAMLQNKRAKFEAAKSGAAGGDTPADGEKSKSGGVLGALGLSGWGKPEAESAASPVPSADQTHKKENPKSSLSTIGEIYGRKPSSSGESSDEPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLV9</accession>
    <name>E3QLV9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_06991</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095867.1">
        <property type="nucleotide sequence ID" value="XM_008097676.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLV9"/>
    <dbReference type="STRING" id="645133.E3QLV9"/>
    <dbReference type="GeneID" id="24412356"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06991"/>
    <dbReference type="HOGENOM" id="CLU_2670926_0_0_1"/>
    <dbReference type="OrthoDB" id="6777263at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032324">
        <property type="term" value="P:molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.190.11">
        <property type="entry name" value="Molybdopterin biosynthesis moea protein, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036135">
        <property type="entry name" value="MoeA_linker/N_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63882">
        <property type="entry name" value="MoeA N-terminal region -like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ31847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="75" mass="8016" checksum="AF826EA036F99288" modified="2011-01-11" version="1">MDGYAAYSKATTLASPERPLLLRVCWAVAAGDEPTELDERTFHGAVEPCLKITTGGIFPKVQGAISCWRSESSTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLW7</accession>
    <name>E3QLW7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_06999</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095875.1">
        <property type="nucleotide sequence ID" value="XM_008097684.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLW7"/>
    <dbReference type="GeneID" id="24412364"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06999"/>
    <dbReference type="HOGENOM" id="CLU_3106232_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178610" evidence="1">
        <location>
            <begin position="19"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="51" mass="5315" checksum="597129F701791CA3" modified="2011-01-11" version="1">MVLLSVLAWLQRTMFLEAESDCCTTAAAVGLDDVYGPSISPIAGVVTAAAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QM71</accession>
    <name>E3QM71_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">homoisocitrate dehydrogenase</fullName>
            <ecNumber evidence="12">1.1.1.87</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_07103</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(2R,3S)-homoisocitrate + NAD(+) = 2-oxoadipate + CO2 + NADH</text>
            <dbReference type="Rhea" id="RHEA:11900"/>
            <dbReference type="ChEBI" id="CHEBI:15404"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57499"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.87"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="11">Amino-acid biosynthesis; L-lysine biosynthesis via AAA pathway; L-alpha-aminoadipate from 2-oxoglutarate: step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.87" evidence="12"/>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095979.1">
        <property type="nucleotide sequence ID" value="XM_008097788.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QM71"/>
    <dbReference type="STRING" id="645133.E3QM71"/>
    <dbReference type="GeneID" id="24412468"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07103"/>
    <dbReference type="eggNOG" id="KOG0785">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031953_0_1_1"/>
    <dbReference type="OrthoDB" id="10261637at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047046">
        <property type="term" value="F:homoisocitrate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004449">
        <property type="term" value="F:isocitrate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006102">
        <property type="term" value="P:isocitrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.718.10:FF:000012">
        <property type="entry name" value="Homoisocitrate dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.718.10">
        <property type="entry name" value="Isopropylmalate Dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835">
        <property type="entry name" value="DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835:SF48">
        <property type="entry name" value="HOMOISOCITRATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isopropylmalate dehydrogenase-like" evidence="13">
        <location>
            <begin position="7"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00052540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00060720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00066666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ31959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="356" mass="38085" checksum="E1847014D9E62DC4" modified="2011-01-11" version="1">MSVRTLRIGLIPGDGIGKEVIPAGRRVLEALPSYLGLKFEFTDLKAGFETFEQTGAALPDKTVEVLKKECDGALFGAVSSPTNAVKGYSSPIVALRKKLDLYANVRPVKTVLTAAKPIDMVIVRENTEDLYVKEEKTYDGPNGKVAEAIKRISEHASHRIAAMAGDIALRRQKIRDAGAASIHKSPLVTITHKSNVLSQTDGLFRATSKLALSDPRFASVAVEEQIVDSMVYKLFRQPEDYDVIVAPNLYGDILSDGAAALVGSLGLVPSANVGEGFAIGEPCHGSAPDIQGKNIANPIATLRSAALMLEFLNEETAAAKIYAAVDANLEEGKFLSPDLGGTAKTDEVVEDILRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMF0</accession>
    <name>E3QMF0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="11">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">GLRG_07182</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="11"/>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096058.1">
        <property type="nucleotide sequence ID" value="XM_008097867.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMF0"/>
    <dbReference type="STRING" id="645133.E3QMF0"/>
    <dbReference type="GeneID" id="24412547"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07182"/>
    <dbReference type="eggNOG" id="KOG0343">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_26_1_1"/>
    <dbReference type="OrthoDB" id="10259640at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17941">
        <property type="entry name" value="DEADc_DDX10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025313">
        <property type="entry name" value="SPB4-like_CTE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13959">
        <property type="entry name" value="CTE_SPB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01178">
        <property type="entry name" value="DUF4217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 11 16" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="8 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="15">
        <location>
            <begin position="53"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="84"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="281"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="497"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="678"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="10">
        <location>
            <begin position="53"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="513"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="523"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="678"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="705"/>
            <end position="725"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EFQ32038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="808" mass="90516" checksum="14FD39DF08A3F2BF" modified="2011-01-11" version="1">MATPTKAPAKGPRKKQSKVLKRDTKLERRKQQLQTIEQLEKAVADFDLKSEYKNFSDLPLCEATRTGLDKSHFETLTDIQSRALPLALKGSDILGAAKTGSGKTLAFVIPVLEKLYRARWTEYDGLGALIISPTRELAAQIFEVLRKVGRNHSFSAGLVIGGKSLKEEAERLSKMNILVCTPGRMLQHLDQTAGFDVDNLQILVLDEADRIMDMGFQSAVDALVEHLPATRQTLLFSATQSKKISDLARLSLRDPEYVSVHEESTPKNLQQHYILTPLHEKLDTLYGFIKANLRSKIIVFFSSGKQVRFAYESMRHLQPGIPLLHLLGKQKQLQRMEITKRFADANYSCLFATDVVARGVDFPAVDWVVQVDCPEDADTYIHRVGRTARYERDGKAVLFLDPSEEAGMLKRLEAKKVPIQKITVKENKKKSIKDQLQSMCFQNPDLKYLGQKAFISYVRSVYLQKDKEVFKFDELDLDTYAASLGLPGAPQIKLRKGEDIKKIKNAPRRGMSSDEDSEGEDPDAPKKPKKPEVRTKYDRMFERTNQDVLSGHYTKLVANGDEVTGDTGAADGDDNDDFLSVKRVLGDDELDAESGKAPGGRAKVITYGDQQFVVDSKRREKALKSKKKMLKFKGRGQKLVFDDDGNAHAIYELRDEEDFGREGPAEELRQKFVADEAARVKEADAEDKAAAKERLKEKRLKRKAREAEERGEGAPRLIEGPRVDAGEMDEDPLALLRSLPIAGGGGGGGDGDSEDGRPKKKPKKWFQDDSDDEREKRKKAKKAGKVLEIDREPETLEDLEALASGLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMH0</accession>
    <name>E3QMH0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Biotrophy-associated secreted protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_07202</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008097887.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMH0"/>
    <dbReference type="GeneID" id="24412567"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07202"/>
    <dbReference type="eggNOG" id="ENOG502S1KA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_124589_0_0_1"/>
    <dbReference type="OrthoDB" id="2132010at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180612" evidence="2">
        <location>
            <begin position="18"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="92"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="171"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ32058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="199" mass="18239" checksum="DD7A2939A1FCD691" modified="2011-01-11" version="1">MVRLSFAAALFAATALAIPSPLMPDPAGAKNVGNGRGAQFIGGACLNSKDCASACCATLNGAGICSGLGAQMQAGKQGCGFGDGGAAPAPPQGAGQAPPSMEAAASNGSPAGSGAPGSSNVGAGNGQQFITGQCLSDADCASGCCAGPKGACAARAVAEENGKSGCGFTGAGSAAGNAAPPATPPQTPPSAGGGSPGVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QML0</accession>
    <name>E3QML0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcription factor Tos4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_07242</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096118.1">
        <property type="nucleotide sequence ID" value="XM_008097927.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QML0"/>
    <dbReference type="STRING" id="645133.E3QML0"/>
    <dbReference type="GeneID" id="24412607"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07242"/>
    <dbReference type="eggNOG" id="ENOG502RZJP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027207_0_0_1"/>
    <dbReference type="OrthoDB" id="5348546at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="117"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="354"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="225"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="374"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ32098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="527" mass="57812" checksum="38557FF3498635D4" modified="2011-01-11" version="1">MMDSSPQSTKLQEPMLPLAGTKRSAPSLLPAFEPLSSSPGFPRPSKRQARTCSVGGANAYLKYPTPIPTSSTGILSSSPPRVHQRPGGSSRALSAGSERTPLGAVASIELNANGETLLMGRSSNSSHYQLSANRLVSRVHVKARYVPAPSALEPNKIEIICNGWNGVKLHCQGRTWELLKGDSFTSETEGTEIMLDVQDSRVMIQWPKRDRRHRLASPDDSAWGDSPPRSAARAAADLLQSSPLRRPSRIESPESPTPAHLSSSQRLQALLPTDDGEVHIYEDSNAEEPELPKLVESATIVGESFATEATNSFSSELSEPEHVNDPDEENDPIVHSFGPFGADISNRLASITTASPKFPPFKRSGLSTTHDEANAPNPSSPISAPPKSIKKEEEEEEEEEDNGEPRKAQPPYENPVVRNHVVNQLAFSRLSSNPLSTIMNNLPSEEKKGLTKDQLRSLIEATACIGIIQRQGKDAAGQPLESEYYYVPEFDDDDQRRLAVTDGLRKPSLRACRKQHKQYYWKRPRTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMQ4</accession>
    <name>E3QMQ4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">CPSF A subunit region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_07286</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096162.1">
        <property type="nucleotide sequence ID" value="XM_008097971.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMQ4"/>
    <dbReference type="STRING" id="645133.E3QMQ4"/>
    <dbReference type="GeneID" id="24412651"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07286"/>
    <dbReference type="eggNOG" id="KOG1897">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002893_1_1_1"/>
    <dbReference type="OrthoDB" id="433457at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018846">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058543">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050358">
        <property type="entry name" value="RSE1/DDB1/CFT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004871">
        <property type="entry name" value="RSE1/DDB1/CPSF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
        <property type="entry name" value="DNA REPAIR/RNA PROCESSING CPSF FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10433">
        <property type="entry name" value="Beta-prop_RSE1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23726">
        <property type="entry name" value="Beta-prop_RSE1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03178">
        <property type="entry name" value="CPSF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101898">
        <property type="entry name" value="NHL repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RSE1/DDB1/CPSF1 first beta-propeller" evidence="4">
        <location>
            <begin position="12"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 second beta-propeller" evidence="5">
        <location>
            <begin position="431"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 C-terminal" evidence="3">
        <location>
            <begin position="798"/>
            <end position="1132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ32142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1163" mass="127886" checksum="07E7A85085D941B4" modified="2011-01-11" version="1">MSYVAPIHRPSSIRHALSVRLSEDDETESLVVARSNRLEVWRVTPTDMYMLGSAVVYGTILLLQRLRPKDSNADLLFVGTDRFQYFTARWGPGTQRLHTEQVIEDAAEPHMRDAQSQDKCLVDPTGRFMAMHLWEGVMNVMRLGNRKGQFARLDGAWEQVRLSELFVKASAFVPTDTGNPTIAFLYQSNIDKEDARLAIYRLMGDDKNTNVSRFDPSKDREYELDIKDPYARIIIPVPIIEDDVKRYHKRDTTGSKAQLGGLVVVGETLLVYVDTLTGTVVEEGLDSPAIFVAWAAYDHTNYFLSDDYGNLHLLTIQTEGVVVTGLFMRMLGVTSRASCLVYMGDGMLFLGSHYGDSQLLSVSVETETTKLVQTIPNIAPILDFSIMDLGNAGDSQVGNAFSSGQARIVAGCGVHQNGSLRSIRSSVGLEDIGVLDDLRDVRGLFSLRSYGSAKVDTLVVSFITETRVFRFDPEGGIEEVFDFQGLVLDRPTLVATTLPSGHLLQITATAVTVLDSESGVTLSTWAVPDGKTIVNASANNKWALLSISGTTLVSLNLSDNLSAQEQVLCRPIGGQEDQISCIHAARDLDDIGVVGFWATGSVSIIHLGTLHALQGETVKQTDDSVSVPRDLALVQLHPPHLLGPTLFVAMEDGQVVSFNVSKEDFSLSSRKSVTLGSQQAGLHILPRPGDEGISNIFATTEHSSLIYSSEARVMYSAATAEDVTYIAPFDSEAFPDAIFLATNRNIRIAHIDPERRTHVNPLQLRETVRRVAYSPALRAFGIGTIHRELTNNEEVVTSSFQLVDEIVLGVVGKPFHLDGSISAEMVESVIRAELPDSMGQPAERFIVGTSYLADPDIDESGDTKGRILVLGVDSDKNPYLIVSHELKGACRSLGVMGEKLVAGLSKTVVVYDYVEESTTSGALRKLATFRPSTFPVDIDVHGNMIGIADLMQSLTLVEFVPAQDGNKAKLVERARHFQYIWATSVCHLEGHSWLEADAQGNLMVLRRNPNAPTEHDRKQMEVTGEFHLGEQVNKIRSLDITPNENDPIIPKAFLATVEGSLYVFADIKSEYQSLLIQFQERLAEVVRALGQADGEPGSGLSFTTWRGFRNAKRAAEGPFRFVDGELIERFLDLDEAKQEAVVQGLGPTVESMRNLVEELKRMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMV1</accession>
    <name>E3QMV1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Aminotransferase class I and II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_07333</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697360">
        <property type="protein sequence ID" value="EFQ32189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096209.1">
        <property type="nucleotide sequence ID" value="XM_008098018.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMV1"/>
    <dbReference type="STRING" id="645133.E3QMV1"/>
    <dbReference type="GeneID" id="24412698"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07333"/>
    <dbReference type="eggNOG" id="KOG0257">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034385_1_0_1"/>
    <dbReference type="OrthoDB" id="2108at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050596">
        <property type="entry name" value="AspAT/PAT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46383">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46383:SF1">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="7">
        <location>
            <begin position="106"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ32189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="465" mass="52267" checksum="1F9EF18E798CC176" modified="2011-01-11" version="1">MFNNRKFSINRHTGVPKPRRFSIGEIGGNEVQSKTHRQFRNAHEGHQPHAGLDASRSSTGVVWCTERASEYGFLEDPDSWANLGQGAPEVEDDIAGCFPRPTTIDISMAGREYGPTAGIKELREAVANLYNVMHREGKDSKYTWENVAIVPGGRAGLIRIAAVLGNSYLSFFLPDYTAYNEMLSLFKNFSAIPVPLSEEDGYHIHPDRIAEEISRGSSVILTSNPRNPTGRVVANPELAEIQDICRGRATFVSDEFYSGYNYTSNCDGNTISAAENVEDVDEDDVLIIDGLTKRFRLPGWRIAWILGPKEYIKAIGSCGSYLDGGANHPFQEAAIPMLDPTLVKAEMVFLQKHFRDKRDYVVRRLREMGFIIKYVPDSTFYLWLNLEGLPGQISDGLNFFQACLEEKVIVVPGIFFDLNPSRRRDLFDSPCHHFVRFSYGPKMETLKKGCDGIERVVNKFRKSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNQ8</accession>
    <name>E3QNQ8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Exonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_07685</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the REXO1/REXO3 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697362">
        <property type="protein sequence ID" value="EFQ32415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096435.1">
        <property type="nucleotide sequence ID" value="XM_008098244.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNQ8"/>
    <dbReference type="STRING" id="645133.E3QNQ8"/>
    <dbReference type="GeneID" id="24413050"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07685"/>
    <dbReference type="eggNOG" id="KOG2248">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1299611_0_0_1"/>
    <dbReference type="OrthoDB" id="16516at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047021">
        <property type="entry name" value="REXO1/3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801:SF115">
        <property type="entry name" value="FI18136P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801">
        <property type="entry name" value="RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuclease" evidence="8">
        <location>
            <begin position="51"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="36"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ32415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="212" mass="23637" checksum="459A79352F59A71E" modified="2011-01-11" version="1">MSSVTLSKEHERAHCQKGFLTDSAKNEHAQMKDASEATQKATIASEPPSSATCRGENELIQITMIDFLSGKVLQSCLVNPSRPIIDWREDITGISTVLHDWEAARAELWRFADKERILIGQSVYSDLKVLHVSHSRIIDSAIVTADAVLGKNLKIRKRWGLKTLCDELLGIRIRESSKKGWLWSSRCFGRCSCNERGGAAMCPRARQAKTLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNS0</accession>
    <name>E3QNS0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Oxalate decarboxylase family bicupin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_07697</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="3">Binds 2 manganese ions per subunit.</text>
    </comment>
    <dbReference type="EMBL" id="GG697362">
        <property type="protein sequence ID" value="EFQ32427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096447.1">
        <property type="nucleotide sequence ID" value="XM_008098256.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNS0"/>
    <dbReference type="STRING" id="645133.E3QNS0"/>
    <dbReference type="GeneID" id="24413062"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07697"/>
    <dbReference type="eggNOG" id="ENOG502S8GB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030515_2_0_1"/>
    <dbReference type="OrthoDB" id="10263073at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033609">
        <property type="term" value="P:oxalate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20305">
        <property type="entry name" value="cupin_OxDC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20304">
        <property type="entry name" value="cupin_OxDC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017774">
        <property type="entry name" value="Bicupin_oxalate_deCO2ase/Oxase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006045">
        <property type="entry name" value="Cupin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051610">
        <property type="entry name" value="GPI/OXD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03404">
        <property type="entry name" value="bicupin_oxalic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35848">
        <property type="entry name" value="OXALATE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35848:SF9">
        <property type="entry name" value="SLL1358 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00190">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00835">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179885" evidence="5">
        <location>
            <begin position="24"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin type-1" evidence="6">
        <location>
            <begin position="151"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin type-1" evidence="6">
        <location>
            <begin position="333"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="29"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="438"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="378"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="380"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="385"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="424"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR617774-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR617774-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ32427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="506" mass="54987" checksum="DDA69E58CEDFEF56" modified="2011-01-11" version="1">MIFIPKHGIFLVGLLGALPKGSAIPAPQMGDYGENKGPVGGVSPPISSVTAPTGSLRGDASLLGGNAPLPDPDKSDSAVVNDVQLVPGQKADGKLGLYLNFDGVDVPQPIRGELGSPDPGPRTYAYEKLNPDIFAPPGTDKGDVENAMWPLGLSHNRLGSQPGAGWARQQNTDVLPIASRMAGVDMRLQPNAYRELHWHRSAEWALMLKGTCRIAAMNEDGKSFVDDITAGDVWFFPKGVPHSIQAFDQGAEFLLVFDDGGFSEEDTFLASELFLRNPLSVLSKNFKADISAFDKIPKDQLYIFNGTPPPKDIQEQNQTSSAGSLVGADSYTYHWSQQKPYQVPGGSVKILDPQTFPIASNFSSALVVVQPGAMREIHWHTTSDEWNYFLQGSGRITIFEAPEASRTFDFTAGDIGYIRVGDSHYIENTGTEDVIFLEVLQAPRFSDISVAQWLALTPKQVVKDTLNLPDDVIDALPREKEFIKVGNPNMTALASGGKNFKRRFQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNY1</accession>
    <name>E3QNY1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_07583</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697363">
        <property type="protein sequence ID" value="EFQ32569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096589.1">
        <property type="nucleotide sequence ID" value="XM_008098398.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNY1"/>
    <dbReference type="STRING" id="645133.E3QNY1"/>
    <dbReference type="GeneID" id="24412948"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07583"/>
    <dbReference type="eggNOG" id="KOG1575">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_0_1"/>
    <dbReference type="OrthoDB" id="1720422at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF9">
        <property type="entry name" value="OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="26"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ32569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="256" mass="28901" checksum="82D89D5E9F13132D" modified="2011-01-11" version="1">MTKCAMPVGEDVGLFTPMYAQQIGQSKDYVNQGGLSRKTIFKAVDDALDRLGTTYIDLFQIHRFDPATPIEETMKALHDLVQAGKILYIGASSMWATQFAQIQFAAEKNGWTKFVSMQNFYNLVYREEEREMIRFCKETGVGIIPWSPLFGGALGRSLKSDKASIRSQVKGLMNPGLTETDKSIIRRVEEVAEQKGWSMSHVALTWIRCKGGIPITGFNSIKRVDEAGELRGKTLTEDEMKYLEEPYIPRNIIGHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPV1</accession>
    <name>E3QPV1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">NUDE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_08022</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nudE family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697365">
        <property type="protein sequence ID" value="EFQ32878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096898.1">
        <property type="nucleotide sequence ID" value="XM_008098707.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPV1"/>
    <dbReference type="STRING" id="645133.E3QPV1"/>
    <dbReference type="GeneID" id="24413387"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08022"/>
    <dbReference type="eggNOG" id="KOG1853">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034391_0_0_1"/>
    <dbReference type="OrthoDB" id="5877028at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005871">
        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051642">
        <property type="term" value="P:centrosome localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000132">
        <property type="term" value="P:establishment of mitotic spindle orientation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047496">
        <property type="term" value="P:vesicle transport along microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033494">
        <property type="entry name" value="NUDE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006964">
        <property type="entry name" value="NUDE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10921:SF1">
        <property type="entry name" value="NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10921">
        <property type="entry name" value="NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04880">
        <property type="entry name" value="NUDE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NUDE" evidence="8">
        <location>
            <begin position="131"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="208"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="364"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="540"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="220"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="279"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="301"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="331"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="402"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="456"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="565"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ32878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="596" mass="65394" checksum="D8827F8ADA7206F4" modified="2011-01-11" version="1">MAEPPSSPPNEAASSEDQLRWYKSQYASLEEELAEFRESSKELEQELEKDIEQAEKRERKLQEKAESLKFEAEEWKSKYNQAKKDANAAQNALEKEITMLRDTNRTLQMKLRDIEVVNDDFERQARNTSSSLEDLESKLNSSIERNVMMEEEIRIGEQERETLRIEAQRLREELSDLKIEAELLQDKIKKQEARHLSAISTDLSILSSSPTFDKTLDASPGSTASSPMVSTPPDDESLLVNKKSQISEPPSPPMSDVSSSVPKRTVSRTPLKTPAKTPASATRKSRLPSTEHSITPKPRSFTASISSSRPTGSRPSAGASTRTPAPRTAPRSISTRMPANNSLNHIRSLTAQMQRLEARVHNVRSKLPAPVTTPPRASPRSSVLGVHSVPSTVTIRSRKRPTGSTASRDDTTPSNFSASTRSKHVPRLSTSGVSRLSFGPLPNRNPGAGTGIENESGISRPSSRASISSYARPSSRTEMAPPRPMSRTSMSGTRTPMVRPRSSLGGGLHARSASISSRIDIEEGDETGEYITPSRRGTFSRLESETAMSGIPLPASGIPMRSSRRQSGSSVSGRQSSMGLRGSVMGNRELVEEETY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQG1</accession>
    <name>E3QQG1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Amino acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_08243</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697367">
        <property type="protein sequence ID" value="EFQ33099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097119.1">
        <property type="nucleotide sequence ID" value="XM_008098928.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQG1"/>
    <dbReference type="STRING" id="645133.E3QQG1"/>
    <dbReference type="GeneID" id="24413608"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08243"/>
    <dbReference type="eggNOG" id="KOG1286">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007946_12_0_1"/>
    <dbReference type="OrthoDB" id="3900342at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000017">
        <property type="entry name" value="Amino acid permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004840">
        <property type="entry name" value="Amino_acid_permease_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF12">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
        <property type="entry name" value="AMINO_ACID_PERMEASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="107"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="151"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="300"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="354"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="400"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="429"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="470"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="513"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="8">
        <location>
            <begin position="73"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ33099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="576" mass="62871" checksum="F04FC93CFECD2217" modified="2011-01-11" version="1">MAAQEGVIPTKVEADEKAIGRAPAYDSSSGKDVRGAISEESWATRAGLNLTSFKKREYGRGVVELDRAMSKRHLHMIAIGGSIGAGFFVGSGGALSKGGPGSLFIDFFLVGIMMFNVVYALGELAVMYPVSGGFYTYSTRFIDPSWGFAMGWNYVFQWAIVLPLELTVSGLVVQYWNKDISVAVWITVFLVAIIIINIFGSIGYAEEEFWSSCIKLGATVIFMIICLVLVLGGGPESGRYHEYQGAKLWYDPGAFRNGFKGFCSVFVTAAFSFSGTELVGLAAAEAKNPVKSLPGAIKQVFWRISLFYILGLFFVGLLIPSDDPSLLSESSYSDVKASPFVLVGKYAGLVGFDHFMNCVILVSVLSIGVSGVYGGSRTLTALAQQGYAPKIFTYIDRSGRPLPSVFAILIFGPLAYVNLNASGPVVFDWLLALSGLAAVFTWGSICLAHIRFRKAWAYHGHTIDEIPFKAIGGTTGSWIGLFLCFVVLAAQFYTAIAPPGTDELNGAEGFFKSYLALPVVMIFWLGGFLWKRTGWLRTAQMDVDTGRRELDWDEVHAYRARLAAMPAWKRAIHHVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQS8</accession>
    <name>E3QQS8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_08360</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697368">
        <property type="protein sequence ID" value="EFQ33216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097236.1">
        <property type="nucleotide sequence ID" value="XM_008099045.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQS8"/>
    <dbReference type="GeneID" id="24413725"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08360"/>
    <dbReference type="eggNOG" id="ENOG502RQT0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079446_0_0_1"/>
    <dbReference type="OrthoDB" id="5358884at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ33216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="274" mass="28697" checksum="305397F6E9CD19D1" modified="2011-01-11" version="1">MASQYDEGPELAPQNQFPEVYNPLPQHSQTGTPHPAPVTPLTHEDSTYGKYSVSAVDQSAYGGAQYQPDGSQKKRKTICGCTFLVFLLSVVIAVLAAAVIGLAAGTGVEASRANEALEQLASLQASVTAGGSATATVTATGASATATGFASITNNCSDADETTTNQTYTTDFYGKKTFVQYCNSNAPNPPLMSLFTANFDNCMDACAAFTSYEPGFNGNATCQAVSFIPLWTTREGAVKGKAPGNCYLKPGPQTRDKLETPNIGTECHAAIMNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QR70</accession>
    <name>E3QR70_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ATP-binding cassette transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_08502</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697369">
        <property type="protein sequence ID" value="EFQ33358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097378.1">
        <property type="nucleotide sequence ID" value="XM_008099187.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QR70"/>
    <dbReference type="STRING" id="645133.E3QR70"/>
    <dbReference type="GeneID" id="24413867"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08502"/>
    <dbReference type="eggNOG" id="KOG0054">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1906591_0_0_1"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042626">
        <property type="term" value="F:ATPase-coupled transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF345">
        <property type="entry name" value="ABC MULTIDRUG TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="3">
        <location>
            <begin position="8"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ33358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="133" mass="14718" checksum="8E2255BF0F51D09B" modified="2011-01-11" version="1">MPANRIDRYTLRRRIIAASQDAVFLPDGSTVRENLYPFRVADEAECLSVLEQVGLRAGVQERGGIDANFTAESLSQGRKQLLCLVRAVLRQCVKSRNGTNGGILLLDEVSSSVDQATDIAMQDIIRREFDGYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRB6</accession>
    <name>E3QRB6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pirin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_08683</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="2">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pirin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697370">
        <property type="protein sequence ID" value="EFQ33404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097424.1">
        <property type="nucleotide sequence ID" value="XM_008099233.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRB6"/>
    <dbReference type="STRING" id="645133.E3QRB6"/>
    <dbReference type="GeneID" id="24414048"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08683"/>
    <dbReference type="eggNOG" id="ENOG502QQ5A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045717_0_2_1"/>
    <dbReference type="OrthoDB" id="198735at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02247">
        <property type="entry name" value="cupin_pirin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02909">
        <property type="entry name" value="cupin_pirin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012093">
        <property type="entry name" value="Pirin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008778">
        <property type="entry name" value="Pirin_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003829">
        <property type="entry name" value="Pirin_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13903:SF8">
        <property type="entry name" value="PIRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13903">
        <property type="entry name" value="PIRIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02678">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05726">
        <property type="entry name" value="Pirin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006232">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pirin N-terminal" evidence="4">
        <location>
            <begin position="22"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Pirin C-terminal" evidence="5">
        <location>
            <begin position="177"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006232-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ33404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="302" mass="33237" checksum="697ADEAD548B3F5F" modified="2011-01-11" version="1">MSVPRAIRKVFLAVEQAEGAGARVRRSIGTPQLRNFSPFLMLDHFRISPGAGFPDHPHRGQETITYLLHGGVDHEDFAGNKGTIEAGDLQFMTAGRGIMHAEMPKQNPDGSANVGLQLWVDLPKHLKSCEPRYRDLRAKEIPSVDVDGGKVHVKVISGQSHGVDSVRDLAYTPVWILDIQIKPGGKIAQPLPKGWNTFAYTLEGQAIFGTGAQQRVVDEFHNVVFEEDGEIVNIEVDAGAEKDARLVLIAGTPLDQEIVQYGPFVLSSKAEVYQALMDYQTHSNGFERAKGWESEIGKTMVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRG9</accession>
    <name>E3QRG9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Dual specificity phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_08736</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697370">
        <property type="protein sequence ID" value="EFQ33457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097477.1">
        <property type="nucleotide sequence ID" value="XM_008099286.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRG9"/>
    <dbReference type="STRING" id="645133.E3QRG9"/>
    <dbReference type="GeneID" id="24414101"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08736"/>
    <dbReference type="eggNOG" id="KOG1716">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003560_1_0_1"/>
    <dbReference type="OrthoDB" id="273181at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008138">
        <property type="term" value="F:protein tyrosine/serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033260">
        <property type="term" value="P:nuclear DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14516">
        <property type="entry name" value="DSP_fungal_PPS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000110">
        <property type="entry name" value="PPS1p Protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053239">
        <property type="entry name" value="Dual_spec_PTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047949">
        <property type="entry name" value="PPS1_DSP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47550">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE PPS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47550:SF1">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE PPS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="4">
        <location>
            <begin position="514"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="5">
        <location>
            <begin position="582"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ33457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="693" mass="76890" checksum="4ED69DF74DAE8EF7" modified="2011-01-11" version="1">MATIALPRPIPPHRPTSTVSAVPSISLEPIGTAQVPVPNKHLPVCPPGPVPAEEPNTPPPSPPHDDDEPAQQSSLLYPPSKFSRYESGPVAVYTIRPADVAAALDYISRQPLPDPNQVFPWFHGLHPHNHIQQSFFIARHRSLRKTPTCVRGVTLVKADGDLSVARLKGAIAPQEFIHLTAAPEFLDVDPRDGFCVRNFQIQAAKAAMISDIVVYGEDDEAVRKLGLDIATAQLRWRQRHETQGHTIPEYNTFLCVAPFEHFEKDHNDIVAVDAQGRLTGNVLDFFHQERKEMCNMTKASEISHNVWLGPTPDPASGEEDQFDVLIECSDVGRLNPSALRALAVSRVEPAQRPYIDFPSSGSILPPTWSQAEADGILETCKWIYHLAHGTLPATSGPGIDVDGDTDMDEQGGSSLVNLRPRKILIHCADGYTESTMLGIAYFSYSTGQGIADAWLHLHTSKKRNFFAYPTDVALLTCIEARLLHESPLHSGKGLREITALIKEPSWLPGLDGSLPSRVLDYMYLGNLGHANNPDLLRALGIRQILSVGETSMWREGDLEQWGPENVCVVQGVQDNGIDPLTDEFERCLDFIDRGRQNGTATLVHCRVGVSRSATICIAEVMRSQGLSFPRAYCFVRARRLNVIIQPHLRFAYELLKWEELNQVKKNGPAGIKRELEWSEITREIALMNRPYAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSP3</accession>
    <name>E3QSP3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_09025</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697374">
        <property type="protein sequence ID" value="EFQ33881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097901.1">
        <property type="nucleotide sequence ID" value="XM_008099710.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSP3"/>
    <dbReference type="GeneID" id="24414390"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09025"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_3_1"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000061">
        <property type="entry name" value="MFS sugar transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF68">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="74"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="160"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="280"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="313"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="345"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="375"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="410"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="439"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="18"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="512"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="512"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="538"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ33881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="549" mass="60891" checksum="910A1BF2825FE0DA" modified="2011-01-11" version="1">MGKLNYFGLRGKSLNWAISIIAGCDFLLFGYDQGVTGGILTLPAFQSQFPTIDSEPEGLLGGLTKSQRSTNQGIAVASYNLGCFLGAIITIFIGNPLGRKRMIILGTAIMVVGAALQASAFSIEHLIIGRIITGLGNGGNTSTVPTWQSETCSSHKRGKLVMIEGALISGGIMISYWIDLGMSFAPGSVSWRFPLALQILFCVFILAFVWNLPESPRWLILKGRDQEAKEVIAAIADLPEDDDYCKNEYVVMKKTVEEMSKGTFKDLFTMDKNRNFHRTCIAYVNQMFQQICGINLITYYAAVIYSGLGMSRFMAHLLAALNGTEYFIASWPAVFLVERVGRRKLMLFGAVGQAITMAILAGVNSQSTYACQITGIVFLFVFNTFFAIGWLGMTWLYPAEIVPLRIRAPANALSTSANWIFNFMVVMITPVAFDSIKHHTYTIFAIINAIIVPVTYFFFPETAYRSLEEMDSIFSKAASGFKGAFDVVNVARHEPHRYGRNGELLVHYDDKETGHATTRENRRENSTSSSEHNGMWARQDEETQKVEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSR2</accession>
    <name>E3QSR2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pectate lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_09044</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697374">
        <property type="protein sequence ID" value="EFQ33900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097920.1">
        <property type="nucleotide sequence ID" value="XM_008099729.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSR2"/>
    <dbReference type="STRING" id="645133.E3QSR2"/>
    <dbReference type="GeneID" id="24414409"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09044"/>
    <dbReference type="eggNOG" id="ENOG502QW7I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016764_1_1_1"/>
    <dbReference type="OrthoDB" id="302705at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052063">
        <property type="entry name" value="Polysaccharide_Lyase_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42970">
        <property type="entry name" value="PECTATE LYASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42970:SF1">
        <property type="entry name" value="PECTATE LYASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180896" evidence="3">
        <location>
            <begin position="21"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ33900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="450" mass="46318" checksum="0EABE00A46E33020" modified="2011-01-11" version="1">MKVSAVLLAAAALFYQGAAAQPCKDASASCGAVRWGDATPAKVAARADSIPLAFPGAEGFGRNAVGGRTGKVYKVTNLSDSGPGSLRDAVSQPNRIVVFDVGGVIKISSRIVVSKNIYIAGQTAPGGGITVYGNGFSWSNANDAIVRHIRIRMGKGGDSGKDAITIADGKNLIFDHVSVSWGREETFSISGDVTNVTVSDSIIAQGLETHSCGGLMQTDGGVSLFRNLYIDNKTRNPKVKGVNDFQNNVVYNWGSGGGYIAGDSAGASYANIVNNYFISGPSTSVAAFTRGNANFRGYVRDNFYDSNRDGALNGAALCVSATCYSDLAIQTAPFAYPPPAKLLAPAAAVAHVSARAGASISRDAVDAALLKELQSYGKSGKLISDEASAGGVGTVAPGTAKRDTDGDGIPDEWETANGLNPNDASDGMKIGAGGYANLEIYVNSLAPAVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QT42</accession>
    <name>E3QT42_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fungal N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_09174</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697375">
        <property type="protein sequence ID" value="EFQ34030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098050.1">
        <property type="nucleotide sequence ID" value="XM_008099859.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QT42"/>
    <dbReference type="STRING" id="645133.E3QT42"/>
    <dbReference type="GeneID" id="24414539"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09174"/>
    <dbReference type="eggNOG" id="ENOG502SCN1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1855123_0_0_1"/>
    <dbReference type="OrthoDB" id="5365701at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ34030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="138" mass="15135" checksum="8AACEAD3AC05DA3C" modified="2011-01-11" version="1">MDPLSIVTAAASLAGAVLKASFKIKETIDAYEDAPQSIADIADEVHAVQIALRQVESVVSQDPDAIERLGLEDVFAIAVNGCHATLLSISKEYENLFLRSDWKAKIQALWKEGEMTRLLGRLDRKKATLTLLTQTLNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTS0</accession>
    <name>E3QTS0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Methanesulfonate monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_09376</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697378">
        <property type="protein sequence ID" value="EFQ34232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098252.1">
        <property type="nucleotide sequence ID" value="XM_008100061.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTS0"/>
    <dbReference type="STRING" id="645133.E3QTS0"/>
    <dbReference type="GeneID" id="24414741"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09376"/>
    <dbReference type="eggNOG" id="ENOG502S7YG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027853_1_2_1"/>
    <dbReference type="OrthoDB" id="2558704at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008726">
        <property type="term" value="F:alkanesulfonate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046306">
        <property type="term" value="P:alkanesulfonate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01094">
        <property type="entry name" value="Alkanesulfonate_monoxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="entry name" value="Luciferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024014">
        <property type="entry name" value="DMSO2_SphG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050172">
        <property type="entry name" value="SsuD_RutA_monooxygenase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04021">
        <property type="entry name" value="LLM_DMSO2_sfnG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42847">
        <property type="entry name" value="ALKANESULFONATE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42847:SF4">
        <property type="entry name" value="ALKANESULFONATE MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="Bacterial luciferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="4 6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Luciferase-like" evidence="5">
        <location>
            <begin position="39"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ34232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="391" mass="44094" checksum="884B234A29D24280" modified="2011-01-11" version="1">MSAQPHPLNTEADRLLFAYWVPNVSGGLIISKIPQKTNWDLASNVKYARAAERAGIEYGLTQIRFTSGYGAANQHESVSFSQAILQATDTIKVIAAILPGPWNPTTVAKQIASIDHYSNGRIAVNIVSGWFKGEFTAIGEWWLEHAERYRRSNEFIRCLKGIWTAPDDTGFTFGGDFYRYRNYVLNPKPVQKPHPEIFQGGNSDDARNNGAEVSDWYFMNGNDLDGFRAQIEDVKARAAKVGRENEVRFAVNGFVIVRETEEEAVRVLQEIQGKADKEAVNAFRDSVQQAGASTSNMKGMWADSKFDDLVQYNDGFKTKLIGTKEQVAERLVLLKSLGVHLVLTAFLHYDDEIEEFGKHVLPLVRQYEKEGRGKDVNFEIERTGDVYRKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTS5</accession>
    <name>E3QTS5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="7">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_09381</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>feruloyl-polysaccharide + H2O = ferulate + polysaccharide.</text>
            <dbReference type="EC" id="3.1.1.73"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the tannase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="7"/>
    <dbReference type="EMBL" id="GG697378">
        <property type="protein sequence ID" value="EFQ34237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098257.1">
        <property type="nucleotide sequence ID" value="XM_008100066.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTS5"/>
    <dbReference type="STRING" id="645133.E3QTS5"/>
    <dbReference type="GeneID" id="24414746"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09381"/>
    <dbReference type="eggNOG" id="ENOG502QPXZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2158198_0_0_1"/>
    <dbReference type="OrthoDB" id="3039123at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030600">
        <property type="term" value="F:feruloyl esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011118">
        <property type="entry name" value="Tannase/feruloyl_esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938">
        <property type="entry name" value="FERULOYL ESTERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938:SF15">
        <property type="entry name" value="FERULOYL ESTERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07519">
        <property type="entry name" value="Tannase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0858">Xylan degradation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ34237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="110" mass="12273" checksum="03CBC5D00C2152B2" modified="2011-01-11" version="1">MGKTPAELDDFYRFFRISGMAHCSGGPGAVNIGNQAQNLASYDPEENVLMAMVRWVEEGIAPEHITGTAFVNNTRSAGVDYKRKHCRWPTRNVFNGTGSYKNENNWECVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3QV39</accession>
    <name>E3QV39_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Topoisomerase II-associated protein PAT1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_09873</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">P-body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PAT1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697383">
        <property type="protein sequence ID" value="EFQ34729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098749.1">
        <property type="nucleotide sequence ID" value="XM_008100558.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QV39"/>
    <dbReference type="STRING" id="645133.E3QV39"/>
    <dbReference type="GeneID" id="24415238"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09873"/>
    <dbReference type="eggNOG" id="KOG4592">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012622_1_0_1"/>
    <dbReference type="OrthoDB" id="74835at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000290">
        <property type="term" value="P:deadenylation-dependent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033962">
        <property type="term" value="P:P-body assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039900">
        <property type="entry name" value="Pat1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019167">
        <property type="entry name" value="PAT1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21551:SF0">
        <property type="entry name" value="PROTEIN ASSOCIATED WITH TOPO II RELATED-1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21551">
        <property type="entry name" value="TOPOISOMERASE II-ASSOCIATED PROTEIN PAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09770">
        <property type="entry name" value="PAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="mRNA decay factor PAT1" evidence="8">
        <location>
            <begin position="1"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="103"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="166"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="517"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="36"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="174"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="195"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="210"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="280"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="304"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ34729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="851" mass="94030" checksum="3C3F58D7731495D5" modified="2011-01-11" version="1">MSFFGFDPSRPSHNTAAPGFSQAHDPFAGLSRGNTEEDDAVEFDDTYDGLGDQLEESGDAFNDDTFGGGGSEAISSAPVGKDFDFFGQTAKVSDAIEEEQVRYSRQVPMAKPAPAPAPTQQQQHYQQQAQPPPNYYYQSQQTSRPVRTGYEKYKEAEPIPDLHVDASLWGMPSKKPPVPEPSPQPQAASASRKVMSLEEVEKAMREQATKRTAQPALSESAPSVQGYPADYGYGRPEAVQQQSFQGLEHHQQRAGQPPQHTSHGQPVTILQRPQSITSKPTPPIQGTPSPLAQPPHSQVPPTQPTQILQNPNRLSGDAARIAGHGQPPHGHHQAHRSQGSMGRVPPVAQQQQQQQHLAHLSEDEKAAYLDQETKRAKRNHKIWVLSKDNGLMTPQDKNFVTRIQLQQLVSATGNPIDQTNDDSLTEDFYYQVLSQIRGGQRQNPNQPLNNFAQTYLFQTGSRQGNMRRQGRAAENHVQRMEQQVQRAVEAAKNKPKNPQLVIAGSLGKISFSNAKTPKPLLNIKRTDSSGDANRPGNGKRHGDSNGLDRKAILRNIEKVYNTIMKMEDHARFIPPPPANGNDEEFHVKHQAWLETAQAYNAQLWNDLKVHEPIGATTIHPFIAFLSFPKGKKAIPRVFRHISFEQRTTILTMIIIHLDQLDVVYGAQATDGEVSLNAAMRESIELFSAAVMPSLFAYFNETELDIVTGVLGLISTKLNIDLIAKTRVGCSMLTLILSRAELLKQGGGGTPQLWAEWEQTFNMFFNKLEPTLHHIFPGSVNTGEDVVVWQLLAAVGVSANPEQQQRLVLAVKDRVLDTVAHAKTLPGAMATTRLATVNLFMHSIGLDVELLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVW7</accession>
    <name>E3QVW7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10149</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697386">
        <property type="protein sequence ID" value="EFQ35005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099025.1">
        <property type="nucleotide sequence ID" value="XM_008100834.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVW7"/>
    <dbReference type="STRING" id="645133.E3QVW7"/>
    <dbReference type="GeneID" id="24415514"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10149"/>
    <dbReference type="eggNOG" id="ENOG502R6P7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_372139_0_0_1"/>
    <dbReference type="OrthoDB" id="4851011at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="424"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="661"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="125"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="322"/>
            <end position="335"/>
        </location>
    </feature>
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        <location>
            <begin position="451"/>
            <end position="473"/>
        </location>
    </feature>
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        <location>
            <begin position="474"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="495"/>
            <end position="513"/>
        </location>
    </feature>
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        <location>
            <begin position="514"/>
            <end position="539"/>
        </location>
    </feature>
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        <location>
            <begin position="564"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="595"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="619"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="693"/>
            <end position="705"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="705" mass="74821" checksum="6DA623DA8CFBA7B9" modified="2011-01-11" version="1">MNADGQEPPTQQQQQQQHGYAPYPPQQQYYAGQQQQQQQQQQQPQYQHNQQYQQYYQQQQPYQAPQQPQYYYPPQQQQQPQPYVSAPTATPQVPPTVATPSHQQNFLAELDASSSATPAAKPGLTPTSTSSPPTAAAQTQHGIPDTGAVFEMSAGATAPRPDNASSKPQTVAAATSPVPAAANASPAEQAGQKPPPPPPIQANPWGFFLPNDDDAPEPSASAFPAKESLADDQTLAVKPLRIVKTGPAEGNPEDRPQGGGGSGAVTEHVALQPWRPAAPEAGAVAEMSGGSRPAGGSPDTLQLAPAPLNIIRPQSPAVQHRPPGSTSPVSSTSPPASQLPYPIDGDGIPTPGSHPAPQPRTQLTLPIHPAATGSPFYPASPTALAPSPLTPSPTGAVAPQPQHYQVAPQPIYTQASPVSPIVVQAGLPPTLPIGSYFPQQPSYARPETTRPAQAPPSAHHSPAPSVSSTATTQLGPQTGQHSPVQSYTSPPPSYNPTTTQSQPATTSPTSLPQFPQPPPQPLSPNPTGVPLPTSPPPSQYPYSPSSVGADKFGFNPHQPPPAPQQQQQQHPYNPHASPPIPQASYVNGPQFYHPIAPPLPPRPSPPMPGQYGQHSTPWPYGPPPPTRPNYQAPPPRPDARFFSSATARKLLGKTTELVDQTITPYLQDHRPRPPYNTYQYQYPNQPPSVPQGQYHQQGYATSQRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWG7</accession>
    <name>E3QWG7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glycerophosphoryl diester phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_10349</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697389">
        <property type="protein sequence ID" value="EFQ35205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099225.1">
        <property type="nucleotide sequence ID" value="XM_008101034.1"/>
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    <dbReference type="AlphaFoldDB" id="E3QWG7"/>
    <dbReference type="STRING" id="645133.E3QWG7"/>
    <dbReference type="GeneID" id="24415714"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10349"/>
    <dbReference type="eggNOG" id="KOG0504">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1162">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG2421">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005444_1_0_1"/>
    <dbReference type="OrthoDB" id="197419at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047389">
        <property type="term" value="F:glycerophosphocholine phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046475">
        <property type="term" value="P:glycerophospholipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14484">
        <property type="entry name" value="SPX_GDE1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
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        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057506">
        <property type="entry name" value="C2_GPCPD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051578">
        <property type="entry name" value="GDPD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22958:SF1">
        <property type="entry name" value="GLYCEROPHOSPHOCHOLINE PHOSPHODIESTERASE GPCPD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22958">
        <property type="entry name" value="GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25329">
        <property type="entry name" value="C2_GDE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="SPX" evidence="6">
        <location>
            <begin position="23"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="518"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="556"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="domain" description="GP-PDE" evidence="7">
        <location>
            <begin position="835"/>
            <end position="1164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="627"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="627"/>
            <end position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ35205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1185" mass="130953" checksum="93783295E18BE1A7" modified="2011-01-11" version="1">MKFGRKCALLSPGNHPNYSIVLGPLSQPLEENADTNPSLPRNQVPEWAAFYINYKGLKKLIKAAAQSAKDGEKVDLAEFFFALDRNLEDVDRFYNRKLGEAVRRLNLLHDRYGRVHDLVSDLDEDETEELMGALYEMRIMLRNLNWFAEINRRGFVKITKKLDKKLPATGSQHRYISTKVDPLPFAKDSTGTRLLAEVNKWISALGEARVVDDSKSDRSVRSLGRASSKAMLTLSQSQLDTLEQAIRNDDVESLKNGLKEGNVASEQASQTLLLNLLQRSIAARSRASMAYLIEQLPSINEPDDINHRNCIHRLVIHIGRTKSSEPDNEPKSYPFPIGTQFTTHDLQPAVSQTIPPRALNQNETKLLGKDDEAVQTLIHLLDTLKPEHREALSARDSFGRMPLHYAARFGFVVVCQIIMAKMQEWNQFNVENGIDAPEWQDNDGYAPLHLSVVGGHPRTTKALLQGENWQGVSVKKAEMRRTVSKSGAVLAIATKCNYQVIVEMLVEAGVDINWQDKTGETALHLAARFGHDGIAKSLIKGTDEQKADLEIAENTYAWTPLHVAAVDGHLAVVQLLVDSGAVVAKADSSGWTAKEHAALRGHLDIARLLANQAEAEIIQPTSSLKISINENSPRSSSPENISSIDGRKSDGYVRPVEPVKTFGHRYLTDKSMVLVSLGSMDMRKNLEAVKLDRVPLTEAHLTELDTALSIVVSASGAQGEPVIVDLPVHETVSTEPIVFTAVDPAQVKLMFDIVPTYSGNEKNKIGRGVALLSSIKPTLGTKRMNLQGDVCVPILANNLDVIGTVNFNFLVVTPFSHPNMEINSQQTYWKKLATTMVIGHRGMGKNMTSNKSLQLGENTVPSFIAAANLGAQYVEFDVQLTKDHVPVIYHDFLVSETGIDAPVHTLTLEQFLHINPDSNRTNGVNAVNERIEKVRNNAPGLRQRSLSMGYAGDGVNGGSLEERMKHTRDFKNKGYKANSRGNFIQAPFATLEDLFRQLPEHIGFNIEMKYPMLHESEEQEMDTYAVELNSFCDTVLSKVYDLAGNRHIIFSSFNPDICLCLSFKQPSIPIMFLTDAGTCPVGDIRASSLQEAIRFASRWNLIGIVSAAEPLINSPRLVRVVKESGLLCVSYGTLNNNPIMVQRQVKEGIDAVIVDNVLAIRKGLTTTEASGESESSEGSETNDSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWZ0</accession>
    <name>E3QWZ0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">SNF2 family domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_10522</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_008101207.1"/>
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    <dbReference type="GeneID" id="24415887"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_000315_2_7_1"/>
    <dbReference type="OrthoDB" id="448448at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18008">
        <property type="entry name" value="DEXDc_SHPRH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF52">
        <property type="entry name" value="SINGLE-STRANDED DNA-DEPENDENT ATPASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="433"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="759"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="867"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="19"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="117"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="21"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="128"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ35378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1015" mass="114374" checksum="C647BA1DAD2EEE27" modified="2011-01-11" version="1">MASLKRLLNKEDEELHYPDLSSVSSYGSIPSPYQAEQDYTGHQPRQTQFQGGPDMSQEATGLENPASMNEDYNSLFPYTDNSQFEPINFGDRPGAVPFDFGQELLIWGRNTIAATPASHAYSSPKPSPGSSQDSPPLTHSPWLIPGCSSIAGSDTSLSAGDDETEMVCYGMLYNVDVKLVGDMGVFDTKIRDTHQRELTHAPPGQTPYQRFNLAEHQDHVVLIFRDDPDVTEFGYLRSGPGTTLARLLAQEGLEFESVAQTAALRETIGRAKKPVEAMVKVDINIYGPRGRAHETGKTLSEGKLYLQMPDHARSGFSYENPHMLRIKDAEHMVTEAAREVNSRAPTGRQPREERLRDMMLEVYQSIQNKRHLRREDGAKGLKHELQEHQKQALAFMLERESGHIVDSAYRLWQPVVEEGQEWFRHKITNIKQKTQPDEKGGGILADEMGMGKSLSILSLIVTTLQNGQQWAQQEEQNDEKSRELCYSGSTLVVVSSALLIYEWNNEIAKHVEGKLNQIEYHGPKREKDIDKIKNSNIVVTTYNTLAAEYEKKSSPLHKIGWYRVVLDEAHVIRRPATTFFHACRALHANSRWCLTGTPIQNKLADMGALFAFIRAKPFDEPAMFRRYIEVPFEQHGDPKKIKDRLILLLDSLCLRRTKELLELPGLEERVKELEFTPAEREQYDKTKKILMRTIKQKVGEVEKSSKFGLFQANLQMRILCNHGTYQKPFSWSRRSYRMSRLEEREAAVSALGQNAEITCDGCHQPMPILGSSQLRNEAEEQCAHVLCSECLDESDMSAPGSRTRHCPVCENWVRTAAAAAATASSPPVRVDGPSASGGDVAMADAPARTSANKDDELYFNQEGYSTKMDALIRDVKEDVWTTKSIVFSCWTRTLHLVGMHLERAGVRFAMIDGNCPLSERQKILERFAKDDDLRVLIMTTGTGAFGLNLTCANRVFIVELQWNPSVENQAIARAIRFGQDQKVLVTRYVTKATVEEEMRSQQIVKKNLAAIGFDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3QX63</accession>
    <name>E3QX63_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoenolpyruvate carboxykinase (ATP)</fullName>
            <ecNumber evidence="3">4.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_10595</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>oxaloacetate + ATP = phosphoenolpyruvate + ADP + CO2</text>
            <dbReference type="Rhea" id="RHEA:18617"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.49" evidence="3"/>
    <dbReference type="EMBL" id="GG697393">
        <property type="protein sequence ID" value="EFQ35451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099471.1">
        <property type="nucleotide sequence ID" value="XM_008101280.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QX63"/>
    <dbReference type="STRING" id="645133.E3QX63"/>
    <dbReference type="GeneID" id="24415960"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10595"/>
    <dbReference type="eggNOG" id="ENOG502QQI5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018247_2_0_1"/>
    <dbReference type="OrthoDB" id="184182at2759"/>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004612">
        <property type="term" value="F:phosphoenolpyruvate carboxykinase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00484">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.8.10:FF:000001">
        <property type="entry name" value="Phosphoenolpyruvate carboxykinase (ATP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.449.10:FF:000002">
        <property type="entry name" value="Phosphoenolpyruvate carboxykinase [ATP]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.449.10">
        <property type="entry name" value="Phosphoenolpyruvate Carboxykinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.8.10">
        <property type="entry name" value="Phosphoenolpyruvate Carboxykinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00453">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001272">
        <property type="entry name" value="PEP_carboxykinase_ATP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013035">
        <property type="entry name" value="PEP_carboxykinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008210">
        <property type="entry name" value="PEP_carboxykinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015994">
        <property type="entry name" value="PEPCK_ATP_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00224">
        <property type="entry name" value="pckA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006820">
        <property type="entry name" value="PRK09344.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006821">
        <property type="entry name" value="PRK09344.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031:SF0">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYKINASE ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01293">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006294">
        <property type="entry name" value="PEP_crbxkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68923">
        <property type="entry name" value="PEP carboxykinase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53795">
        <property type="entry name" value="PEP carboxykinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00532">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="12" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ35451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="591" mass="65570" checksum="0EA2885EDF79883E" modified="2011-01-11" version="1">MKDPVQRTASPYTDPAVKGPKSQILHEGTHADLRKMIASNVNKTPLHPSGVAPHHEHTELEEELHETAHIDYDRVAIIPNASVAALYEDALVYETGSAITSSGALTAYSGKKTGRSPLDKRIVEEDGSKDDIWWGPVNKPMSPEVWKINRERAIDYLNTRNRIYVVDGYAGWDEKYRIRVRVICARAYHALFMRNMLIRPPREELEHFHPDYTIYNAGSFPANRYTEGMTSGTSVAINFAQKEMVILGTEYAGEMKKGVFTVLFYEMPIKHNVLTLHSSANEGKNGDVTLFFGLSGTGKTTLSADPQRALIGDDEHCWSDRGVFNIEGGCYAKTIGLSAEKEPDIFGAIRFGSVLENVVFDPETRIVDYDDSTLTENTRCAYPIEYISNAKIPCRSDSHPTNIVLLTCDARGVLPPISKLDRAQTMFHFISGYTSKMAGTEDGVTEPQATFSSCFAQPFLALHPMRYAKMLADKIEHHNANAWLLNTGWVGAGASQGGKRCPLKYTRAILDAIHSGELAKVEYETYETFNLQVPKTCPGVPSELLNPKAAWVAGNDSFETEVKKLGTLFNENFKKYASEATEEVVKAGPVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3QX80</accession>
    <name>E3QX80_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">2-dehydropantoate 2-reductase</fullName>
            <ecNumber evidence="4">1.1.1.169</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Ketopantoate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_10612</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(R)-pantoate + NADP(+) = 2-dehydropantoate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16233"/>
            <dbReference type="ChEBI" id="CHEBI:11561"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.169"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the ketopantoate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.169" evidence="4"/>
    <dbReference type="EMBL" id="GG697393">
        <property type="protein sequence ID" value="EFQ35468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099488.1">
        <property type="nucleotide sequence ID" value="XM_008101297.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QX80"/>
    <dbReference type="STRING" id="645133.E3QX80"/>
    <dbReference type="GeneID" id="24415977"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10612"/>
    <dbReference type="eggNOG" id="ENOG502QT3Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031468_2_0_1"/>
    <dbReference type="OrthoDB" id="3609at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008677">
        <property type="term" value="F:2-dehydropantoate 2-reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000017">
        <property type="entry name" value="2-dehydropantoate 2-reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003710">
        <property type="entry name" value="ApbA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013752">
        <property type="entry name" value="KPA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051402">
        <property type="entry name" value="KPR-Related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013332">
        <property type="entry name" value="KPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00745">
        <property type="entry name" value="apbA_panE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21708:SF26">
        <property type="entry name" value="2-DEHYDROPANTOATE 2-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21708">
        <property type="entry name" value="PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02558">
        <property type="entry name" value="ApbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08546">
        <property type="entry name" value="ApbA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0521">NADP</keyword>
    <keyword evidence="3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketopantoate reductase N-terminal" evidence="5">
        <location>
            <begin position="27"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="Ketopantoate reductase C-terminal" evidence="6">
        <location>
            <begin position="208"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ35468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="345" mass="37318" checksum="74379772D4D0D38E" modified="2011-01-11" version="1">MGSQTDNSSDSAANIIFIGAGAPGRNVRVSLVARSNYKAINESGVKLQTHSFGNYTFKPHAAFSSVEAAASANKDGCKTQWDYVFVTTKALPDRSDDSAMIAPLIGPSTSIVLIQNGVGVEEPFRQRFPGNPIVSAVTVVSAEQTSPGVVRQNRWTRISIGPHTDGLGTGDPKLGRLGTRAVEQLSMWWGPGWGGIRDVEPHDEIGLQTVRWHKLCINAAFNPSAVLSGGRGNADMVTDPELREHVVGIMNEIRTAVPKILGREFPDDLAKPDRIVKSTERNTGARPSMLLDWEAGRPLELEVILGNPVRIAKAHGVEMPRLQTLYALLKSAQAIREEGTTKSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXC0</accession>
    <name>E3QXC0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Erythromycin biosynthesis protein CIII-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_10652</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697394">
        <property type="protein sequence ID" value="EFQ35508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099528.1">
        <property type="nucleotide sequence ID" value="XM_008101337.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXC0"/>
    <dbReference type="STRING" id="645133.E3QXC0"/>
    <dbReference type="GeneID" id="24416017"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10652"/>
    <dbReference type="eggNOG" id="KOG1192">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000537_4_1_1"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010610">
        <property type="entry name" value="EryCIII-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21015:SF22">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21015">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--N-ACETYLMURAMYL-(PENTAPEPTIDE) PYROPHOSPHORYL-UNDECAPRENOL N-ACETYLGLUCOSAMINE TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06722">
        <property type="entry name" value="EryCIII-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Erythromycin biosynthesis protein CIII-like C-terminal" evidence="2">
        <location>
            <begin position="320"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ35508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="458" mass="50737" checksum="4C6E5B4259138E4C" modified="2011-01-11" version="1">MTATTAERPTKHSPLLLVTAFPGEGHVNPLLTIASYLVKKDYEVVFISTPDFRHRVEEAGAEWVCTDSPFTEELFRSLAETFSLPSVPDRFAIEYKKVFLNTLPPRARKTAEVLALLKARDPNRQIIVIEDALNWSFLPLKYGMPLAQGLTEIPRSIGIGVAAFILESRDTGPIPYGLPPDSTHSGRLRNAILQDLAEKGPLKPALDGLREAMETLGCTDIPTKRMFRCAYTAHDVTLQLCPPSLEYPISDLPPSVEYIGILPRKTPSPDFRYPTWWSEVERTQPDNKYRHVIFVSQGTVASDYTDLVLPAIEAFANRHDVLVVVALGTRGAQLPSEVVIPPNARVLDYMPYDTILEYTDVFISNGGYGALTHAVRNGVPVVLAGESQEKSEVAMRAVYAGLGVSLATQRPTAEQIRKGTDEVLRDTKYRKAVMRLKGEDDSMDALATVEAKVKEMTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXD4</accession>
    <name>E3QXD4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GDSL-like Lipase/Acylhydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10666</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697394">
        <property type="protein sequence ID" value="EFQ35522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099542.1">
        <property type="nucleotide sequence ID" value="XM_008101351.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXD4"/>
    <dbReference type="GeneID" id="24416031"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10666"/>
    <dbReference type="eggNOG" id="ENOG502SSIP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044083_1_2_1"/>
    <dbReference type="OrthoDB" id="3915838at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004622">
        <property type="term" value="F:phosphatidylcholine lysophospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051532">
        <property type="entry name" value="Ester_Hydrolysis_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383:SF31">
        <property type="entry name" value="SGNH HYDROLASE-TYPE ESTERASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383">
        <property type="entry name" value="THIOESTERASE 1/PROTEASE 1/LYSOPHOSPHOLIPASE L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="1">
        <location>
            <begin position="22"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="223" mass="23085" checksum="2F506625D111AFCF" modified="2011-01-11" version="1">MAPRQAQAPAPAPAVPLRIMSLGASVSFGIGSTTGDSYRKDLQDLLVAQGMNVTYVGTKANGDFTDNAVEATPGFKIDQIAAAADEAVPLLQPNLVLVDAGTNNCNKGGIIPDAGANVTAMINNIFAQSPGSTVILTSILANKIAAQDACRVNINAQYADVATQFQQSGAKFALVDMRSPAAPGLNDLNDTRHPNDGGYVKMANVWATGIQEVISQGFITAPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXG7</accession>
    <name>E3QXG7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10699</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697395">
        <property type="protein sequence ID" value="EFQ35555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099575.1">
        <property type="nucleotide sequence ID" value="XM_008101384.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXG7"/>
    <dbReference type="STRING" id="645133.E3QXG7"/>
    <dbReference type="GeneID" id="24416064"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10699"/>
    <dbReference type="eggNOG" id="ENOG502RYMG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026021_0_0_1"/>
    <dbReference type="OrthoDB" id="202545at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42044:SF2">
        <property type="entry name" value="DUF676 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42044">
        <property type="entry name" value="DUF676 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="441" mass="48798" checksum="10FD510B8156B860" modified="2011-01-11" version="1">MLHEDLREMWLMMPGLMASLRTHMANHRQHLSKSHLKDMVVQLSLAIVEVGIITLAIPLFAVLPGILFAAWLGISISIVFGLSWFMNGNEIMVSCDEFGNSTTDIDGDNERWIFIGGMGTSSHHLTQCTIPRLARLFGRSFSGIQMATYGLPFDMILLAIQRCFPLQTQASRALYAELRSVLLDASVHRVAVLAHNNGSLPVANVLARLCSDIQPEKLTKLEIYTFGAAASEFVVPVGESGRKPARFDDGSVVVEERGPHIEHFAYANDPFAQLGVLSSVHKKLESRFCGGVFVIHNQVPQPSGHWVPDQRPVMLLTDYLSALFPDPSSPHAPNSILDYIMMIDRDMAEKRELAAMANYAQTRRSRKDNRRLSWTGLGATVGGKSGVMDGVMGLEMVRRGCRDCDGHRGREVSWLANYVQTGWVVEKESHIVDAMGIGSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXX2</accession>
    <name>E3QXX2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HIT domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_10865</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697398">
        <property type="protein sequence ID" value="EFQ35710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099730.1">
        <property type="nucleotide sequence ID" value="XM_008101539.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXX2"/>
    <dbReference type="STRING" id="645133.E3QXX2"/>
    <dbReference type="GeneID" id="24416230"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10865"/>
    <dbReference type="eggNOG" id="KOG3275">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056776_0_0_1"/>
    <dbReference type="OrthoDB" id="1915375at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019808">
        <property type="entry name" value="Histidine_triad_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001310">
        <property type="entry name" value="Histidine_triad_HIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46648:SF2">
        <property type="entry name" value="HIT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46648">
        <property type="entry name" value="HIT FAMILY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00332">
        <property type="entry name" value="HISTRIAD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00892">
        <property type="entry name" value="HIT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="4">
        <location>
            <begin position="40"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="2 3">
        <location>
            <begin position="132"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-AMP-histidine intermediate" evidence="1">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR601310-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR601310-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ35710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="193" mass="21651" checksum="5F9DC21A559DDF4A" modified="2011-01-11" version="1">MTPTSEFDVGVEPAGSECPFCIIATEYPPYDPIQPPQDDAVLDPNRLPTPAYVVLSTPTLIAFLDILPLSRGHLLLCPRTHRPKLTDASPNESAEMGRYLRILSRALTRTTGVEDWNVVQNNGAAAAQVVMHMHFHLIPRPEIRASGRYSESFTMFGCGRREELDDEDAEHFAKELRENVADILREDKHKSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYD0</accession>
    <name>E3QYD0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase S33 tripeptidyl aminopeptidase-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_11059</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697402">
        <property type="protein sequence ID" value="EFQ35868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099888.1">
        <property type="nucleotide sequence ID" value="XM_008101697.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYD0"/>
    <dbReference type="STRING" id="645133.E3QYD0"/>
    <dbReference type="GeneID" id="24416424"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11059"/>
    <dbReference type="eggNOG" id="ENOG502RY03">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013364_5_2_1"/>
    <dbReference type="OrthoDB" id="425534at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013595">
        <property type="entry name" value="Pept_S33_TAP-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051601">
        <property type="entry name" value="Serine_prot/Carboxylest_S33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248">
        <property type="entry name" value="2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248:SF25">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08386">
        <property type="entry name" value="Abhydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S33 tripeptidyl aminopeptidase-like C-terminal" evidence="3">
        <location>
            <begin position="411"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ35868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="473" mass="51768" checksum="273E1142E2F0A112" modified="2011-01-11" version="1">MSVTAVVSVLLSIEPSANLTWRPCFDDFTCSRLEVPLDYSNTSLGTTSVAFIKLACKNATTQSPSIVLIPGGPGGSGVDLLLQYRTLAGPIFGEQYNFVSFDPRGVNNSGLGLDCFSGNTEARAAFMWLHSTGVTNVSSTSLEEQYYPSSIYGEWCNDAVDCGFTESEAESSGLSPSQAKLWCYGITYGTVVGTTFASMFPDRVGRMILDGVLDAENYYINDWRGNVNQMDEAMERFLTLCHSSGPEKCAFWGPTPADIMAKINIIIDQFRDHPVPVSGVQTRDSPSMVTDSDLKALFINAIYNPLASFPALANTLQQLERGDVSALVGLFDGLWVTSDARLAIQCADSYRRNGLTTTIDEFKAYVEYTVSKSKYIGDIYPIFLENILCRSFRSELSDGMVFQGPIGGPDKPTSYPILFASNTVDPITPLEAARKMSSRFPGSALLLQEAAGHTFKAHFHRPRLRARSNTHRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYE8</accession>
    <name>E3QYE8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_11077</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697402">
        <property type="protein sequence ID" value="EFQ35886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099906.1">
        <property type="nucleotide sequence ID" value="XM_008101715.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYE8"/>
    <dbReference type="GeneID" id="24416442"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11077"/>
    <dbReference type="eggNOG" id="ENOG502RNXE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_589264_0_0_1"/>
    <dbReference type="OrthoDB" id="4817680at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="261"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="297"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="437"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ35886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="488" mass="54259" checksum="7B5414212A45379B" modified="2011-01-11" version="1">MSIPPQASFSSETTAVASHGTAYPSFQELTSFKLPLKDDIVDSTIDDVPDHLNGLKSTRRIAPNPSTPRHPSPVSTETSDGDLTPEDTPSTVHGESMFYPRHPLANLASSIKVPASPRWPFQNVTPRTTVMVPISQSITSSSRALNLSGKRSTIGHVSVSESLDEFQTSHPNAKLLSLHPRPLTYNKIGRNLAKIPELVEKPEWNVQPIHGMPMEHYEKPRRPSPRLFKIRFRRRRRHERHGHSAKPQTFWYQRISVDKKIFRASASITMFFLINSFVSASALITLTTARLPVPHGIVVWVIVSLSTCAFTLTTLCLMRKFRNAVIYDEERGGHSPYPEVPFDVSHMCNMDLPASPTEILHRRQLGTAAAEQEKMQAERTKNGTIVDSRESEVAATTQPCPAGPFGTFVSQHPRDAVAEDYWTDDSVIVSAGSETSSTTAVIPSPPKATVEGRRTGMFDDGPLPQQEDDGYGLGDLELPRWDEWLAWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYQ0</accession>
    <name>E3QYQ0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11132</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697405">
        <property type="protein sequence ID" value="EFQ35988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100008.1">
        <property type="nucleotide sequence ID" value="XM_008101817.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYQ0"/>
    <dbReference type="GeneID" id="24416497"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11132"/>
    <dbReference type="eggNOG" id="ENOG502SXIH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_823892_0_0_1"/>
    <dbReference type="OrthoDB" id="9986683at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028944">
        <property type="entry name" value="PRTase_ComF-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15610">
        <property type="entry name" value="PRTase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180996" evidence="1">
        <location>
            <begin position="30"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="337" mass="38008" checksum="A1E36CFC280D9077" modified="2011-01-11" version="1">MLLLSARQSAVRRLITWLVFAFSFAPSFSFPTNPYHDQTNDVSLVPRQPSLIKDTLVLYYIEDEAKPGFNKYDYSRFKYGDTRFASQYGQEMANLAWKQLIKPILDKDRASHRPLTRFATMVSQGSLPTAATTFESAFCQYLNRYLAAEGAYAVLSVPILKATSASQSGDYATMSDADRENLMNNEHFTFDRQAIEGMVVLNLDDIYITGGHERAIRRTFQEEAAAGRHHDVYYLYIAKLANPKIDPAIETRLNEVAVPQFKDFKSIIEGPMFIIENRFVKRMLKAGSAELKGLLSSLNQGKDFAGRLYDAAIMNDFHMGGNAYKPNLKLVQAMAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYS3</accession>
    <name>E3QYS3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11155</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697406">
        <property type="protein sequence ID" value="EFQ36011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100031.1">
        <property type="nucleotide sequence ID" value="XM_008101840.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYS3"/>
    <dbReference type="STRING" id="645133.E3QYS3"/>
    <dbReference type="GeneID" id="24416520"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11155"/>
    <dbReference type="eggNOG" id="ENOG502QWIR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027441_2_0_1"/>
    <dbReference type="OrthoDB" id="2603at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="255"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="299"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="323"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="372" mass="40955" checksum="ED5B508FF0B91B48" modified="2011-01-11" version="1">MNTFNPRRVSYLRPATAVFEVRDSWASTSSPYPSLSSIGYPASERSDDERFASAVWHRTFNHIDYAAYKAACDAERCAKPERDPDVFSVKSSAARRGLSRLGAMLTIYPYRDMGWLVTMAFIMASISFTLNGIFSLIHLLDPKLDFPGRDTATQVTFVLGSSLLTLSAWMGLLAAINVDRAILDPKKDAPDAYKPALLCSDEFVWVPSWAEFSSIFWPSSAFRAGILQLLAGSFFTIAAVGALPGVLDLTHPNASIIFVSSPQLIGGSFFVLAGLLMIFLSQDKWYIPLILDASWQNGFWNLVGASGFLAVGVVTLLHKNDAVTLASLLLMSGLGFLIASVIQWYIIMEYYPVNPYWEDPVAAAEIPPQSIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYZ6</accession>
    <name>E3QYZ6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_11228</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697408">
        <property type="protein sequence ID" value="EFQ36084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100104.1">
        <property type="nucleotide sequence ID" value="XM_008101913.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYZ6"/>
    <dbReference type="GeneID" id="24416593"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11228"/>
    <dbReference type="HOGENOM" id="CLU_2223089_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ36084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="106" mass="11848" checksum="DD73E4E6B79F6615" modified="2011-01-11" version="1">MPSSFYALALSKFSADYINEYPFLQHPTTANENQWATGAAAAISGHQTAAFIHHPRNHAQGITQSLKDQGVTPSKSQNQVQVQVHLAFLRDAYENAQWHHPHPWTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZ23</accession>
    <name>E3QZ23_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_11255</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697409">
        <property type="protein sequence ID" value="EFQ36111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100131.1">
        <property type="nucleotide sequence ID" value="XM_008101940.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZ23"/>
    <dbReference type="STRING" id="645133.E3QZ23"/>
    <dbReference type="GeneID" id="24416620"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11255"/>
    <dbReference type="eggNOG" id="ENOG502T43H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015190_0_0_1"/>
    <dbReference type="OrthoDB" id="5041951at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="348"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="467"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="15"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="390"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ36111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="612" mass="68985" checksum="864A47596D7BAB7D" modified="2011-01-11" version="1">MALLSPSKGVAPLQQSRLVASVTQLEDIIRNAENEAEKIETDLAYKKAQIADLKFDRIAHNGPTIAFDRVIKRAKSECERIHDDLDSKKEEIAVLKDKLNRRVAKLASIPSVEFADAPTPEDDKEAAALLEITSTQMSEIFTISDDGKTYVKPAMLRGVPIEPINESDKYWEATWVKFNEAIDEDRVEREYQQELDAWHKLTQQGDPLAEEQDLEKGFKRYQRKLNQARVIKKWFRPGSTIHPNQIMAKHHLPGMGLCIAHVLYKICNILGRLGALHERGELGMPPLYFLMWRMSVSLERQPRTHMKTFWRVIIDEDHVAYDEVLRKAEIRGAQHVGDYNFYNRRMKKAVSAKDQRRQPVVSPSATNTALHPPGQPTTPSCKSRDDQYQSTPATTAPSAPSPVGLPMTTLAAEEEPTAHDLQQHQRKRRRSAATAEQQTLEGDRDATSTKKARKAAWKGMQLTLRPVSSAESPASDYTKISPFANDSAMKDMPPSSQGEKETHATVNELPQKVHDVKPNSASGRTAQAWSEYAEEVERRTRSPKIESPGQDASAYFIPVGQDDEFPGIQKDISELRAEVGESPFPKTGKKVSHGFIFPWYCCEAARRADESW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZ35</accession>
    <name>E3QZ35_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CBM1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_11267</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697409">
        <property type="protein sequence ID" value="EFQ36123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100143.1">
        <property type="nucleotide sequence ID" value="XM_008101952.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZ35"/>
    <dbReference type="GeneID" id="24416632"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11267"/>
    <dbReference type="eggNOG" id="ENOG502S1FJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066055_0_0_1"/>
    <dbReference type="OrthoDB" id="70316at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00562">
        <property type="entry name" value="CBM1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180044" description="CBM1 domain-containing protein" evidence="3">
        <location>
            <begin position="23"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="4">
        <location>
            <begin position="24"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ36123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="261" mass="27592" checksum="336649F391A419F7" modified="2011-01-11" version="1">MGLLSILAASLSTTLLTSFVLAQSTIPAWGQCGGNGWSGATTCVSGYTCSILNPFYHQCIPGSSTPTITSAGPVSTSTTPVITPTDTRTTTRASTTLTTVTTTAAGGGGTVPTTLVSGWYWIRAVASPNFHSYLQAKPTLTPSKAYLEAPSSAGQFKIDAGQLVHLTGPSSLYLNVENPTDKTQRKLETWFSTSKNTYGTFAFQGDTLTWSTPDINRPNLAAWLVCENQQVFINTGAYLYQTPAGCFDQTIHSYGGSTADL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZV5</accession>
    <name>E3QZV5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Serine hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11561</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697422">
        <property type="protein sequence ID" value="EFQ36393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100413.1">
        <property type="nucleotide sequence ID" value="XM_008102222.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZV5"/>
    <dbReference type="STRING" id="645133.E3QZV5"/>
    <dbReference type="GeneID" id="24416925"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11561"/>
    <dbReference type="eggNOG" id="ENOG502S1CW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1948683_0_0_1"/>
    <dbReference type="OrthoDB" id="414698at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005645">
        <property type="entry name" value="FSH-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03959">
        <property type="entry name" value="FSH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine hydrolase" evidence="1">
        <location>
            <begin position="12"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="129" mass="14418" checksum="A284505A9BD1A511" modified="2011-01-11" version="1">MLDIDDILATENELRQVIEDHGPFDGLLGYSQGGSMAAQIAIRLLIENPYATLQELPIKFLVLINSAVPPFIMPLDDQKVTDLPIEEAPKLRMLFDVFKADPAEHLDKVRPVKLANGRQVCIERLGHFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0K2</accession>
    <name>E3R0K2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Tubulin beta chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">GLRG_11785</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4 13">Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the tubulin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697452">
        <property type="protein sequence ID" value="EFQ36640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100660.1">
        <property type="nucleotide sequence ID" value="XM_008102469.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0K2"/>
    <dbReference type="STRING" id="645133.E3R0K2"/>
    <dbReference type="GeneID" id="24417149"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11785"/>
    <dbReference type="eggNOG" id="KOG1375">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015718_1_1_1"/>
    <dbReference type="OrthoDB" id="1662883at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000070">
        <property type="term" value="P:mitotic sister chromatid segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097435">
        <property type="term" value="P:supramolecular fiber organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02187">
        <property type="entry name" value="beta_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.600:FF:000003">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.20:FF:000002">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000009">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013838">
        <property type="entry name" value="Beta-tubulin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002453">
        <property type="entry name" value="Beta_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01163">
        <property type="entry name" value="BETATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00228">
        <property type="entry name" value="TUBULIN_B_AUTOREG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10 13" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 13" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="15">
        <location>
            <begin position="47"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="16">
        <location>
            <begin position="246"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="427"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="429"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EFQ36640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="448" mass="49828" checksum="BFD3E52F4203914D" modified="2011-01-11" version="1">MREIVHLQTGQCGNQIGAAFWQTISGEHGLDSSGLYTGTSDIQLERMNVYFNEAASNKYVPRAVLVDLEPGTMDAVRAGPYGQLFRPDNFVFGQAGAGNNWAKGHYTEGAELVDQVLDVVRREAEGCDCLQGFQITQSLGGGTGSGMGTLLISKIREEFPDRMMATFSVVPSPKVSDTVVEPYNATLSIHQLVENSDETFCIDNEALYEICRRTLKLANPSYGDLNHLVSAVMSGVSTSLRFPGQLNSDLRKLAVNMVPFPRLHFFMVGFAPLTSRGSSSFRATTVPELTQQLFDPKNMMAGSDFRNGRYLTCSAIFRGKVAMKEVEDQMRNVQQKNSAYFVEWIPNNVQTALCSIPPRGLKMSSTFVGNSTAIQEIFKRVGEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDAAVDDEEEDYGEEDIPDDVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0Y3</accession>
    <name>E3R0Y3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">2OG-Fe(II) oxygenase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_11915</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697518">
        <property type="protein sequence ID" value="EFQ36771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100791.1">
        <property type="nucleotide sequence ID" value="XM_008102600.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0Y3"/>
    <dbReference type="STRING" id="645133.E3R0Y3"/>
    <dbReference type="GeneID" id="24417278"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11915"/>
    <dbReference type="eggNOG" id="KOG0143">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045863_0_0_1"/>
    <dbReference type="OrthoDB" id="288590at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044283">
        <property type="term" value="P:small molecule biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="3">
        <location>
            <begin position="215"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ36771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="412" mass="45913" checksum="198BFD6E48558426" modified="2011-01-11" version="1">MSSITKGLSKLARPVARKPCLNQARTLASVTDYNVAKLAATMPPGHKATVAQLETFTLPDRVTGSKGDIAMGKALVEAWRRDGILQVSMNDKQRFIFNDATAASKKFFAKTHEEKAACVDSQSYSGYIASGEEITDGIADYSEIFTVTKDLDLAEPRVRAKWPCHGPVPWPDYEMKQPMTTYMDYLGESGEKLLQLTELGLNVPSGSLTNLTDDGWHHMRILRFPPTHNTNGKGKDGRGIGSHTDYGLLVIAAQDDVGGLFIRPPYDGEKFANWEKSSAGLKEEDEGWHYVPPVPNVFTVFPGDVMQYITNSYLPSTPHKVGLNTRDRFAFAYFHEPSFQAVAKPLPGYDAGQSPREGIHYGTHFTNMFLRNYPERVTTKRMNAENRLDLLQKDELRSKGSDRVMPSARKQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q237</accession>
    <name>E3Q237_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00282</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089158.1">
        <property type="nucleotide sequence ID" value="XM_008090967.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q237"/>
    <dbReference type="GeneID" id="24405647"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00282"/>
    <dbReference type="eggNOG" id="ENOG502T65I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1835016_0_0_1"/>
    <dbReference type="OrthoDB" id="10369042at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="140" mass="15839" checksum="760D8F546A1A274A" modified="2011-01-11" version="1">MESNQGSHEQFIGISRAAFLRFRKRQQVKEYYQRSAIEAAFARLLQTASWGRSESKEERDTAVRFAEVVEYIPPTQTPVGTEEQHPCHPCRSELEKPTVNEEEAGTEAAEDDAKSLGITGDDGQDEIAKKMWSVLHPEET</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2E5</accession>
    <name>E3Q2E5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Mpv17/PMP22 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_00390</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089266.1">
        <property type="nucleotide sequence ID" value="XM_008091075.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2E5"/>
    <dbReference type="STRING" id="645133.E3Q2E5"/>
    <dbReference type="GeneID" id="24405755"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00390"/>
    <dbReference type="eggNOG" id="KOG1944">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066033_0_0_1"/>
    <dbReference type="OrthoDB" id="860at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266:SF93">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN 25D9-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="244"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ25246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="277" mass="30102" checksum="041E4A36493A2A7B" modified="2011-01-11" version="1">MSVKFEKETIKKGVEEVKKGLIGEPLPGTSGKHPISEAIGTAVTGGKKNAGTKGYLAAYIRELEKNPLRTKMLTSGTLAGAQELIASFLAKDRNKHGDYFTSRVPKMAAYGALVSAPLGHFLIWALQKTFAGRTSLRAKILQIIVSNLIIAPIQNSVYLTAMALIAGAKTYHQVRATVRVGFWKVMKVSWITSPLCLAFAQKFLPDQLWVPFFNLVAFIIGTYINTITKKKRLAALRKKHFGDGRSPSMGGRPEDYPGPKDYPGPMGGPIGGPNPAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2G4</accession>
    <name>E3Q2G4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein uL13m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_00409</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089285.1">
        <property type="nucleotide sequence ID" value="XM_008091094.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2G4"/>
    <dbReference type="STRING" id="645133.E3Q2G4"/>
    <dbReference type="GeneID" id="24405774"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00409"/>
    <dbReference type="eggNOG" id="KOG3203">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082184_1_1_1"/>
    <dbReference type="OrthoDB" id="274622at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1180.10:FF:000007">
        <property type="entry name" value="50S ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01366">
        <property type="entry name" value="Ribosomal_uL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_uL13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005823">
        <property type="entry name" value="Ribosomal_uL13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023563">
        <property type="entry name" value="Ribosomal_uL13_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_uL13_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01066">
        <property type="entry name" value="rplM_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL13M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="RIBOSOMAL PROTEIN L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002181">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00783">
        <property type="entry name" value="RIBOSOMAL_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 8 9" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00068950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ25265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="179" mass="19898" checksum="A610628C0BEB7634" modified="2011-01-11" version="1">MSQTVGLTRLSYSRVWHHVSASAPHETLSTQPGVTPPSLGRLASRIAVLLMGKHKPTWDPSTDCGDYVVVTDCAALHVTGRKKWQKTYYRHNTRPGSLQAVTMDVLMEKHGGAEVLRKAVSGMLPKNRLRAPRLARLKAFEGEAHPYKKNVIRFGGVPVGQHGWEEQVKAIREADSERI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2G8</accession>
    <name>E3Q2G8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">DnaJ domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_00413</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089289.1">
        <property type="nucleotide sequence ID" value="XM_008091098.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2G8"/>
    <dbReference type="STRING" id="645133.E3Q2G8"/>
    <dbReference type="GeneID" id="24405778"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00413"/>
    <dbReference type="eggNOG" id="KOG0712">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017633_10_0_1"/>
    <dbReference type="OrthoDB" id="550424at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10719">
        <property type="entry name" value="DnaJ_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.230.10:FF:000001">
        <property type="entry name" value="DnaJ subfamily A member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000003">
        <property type="entry name" value="DnaJ subfamily A member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.230.10">
        <property type="entry name" value="Heat shock protein DnaJ, cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01152">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012724">
        <property type="entry name" value="DnaJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044713">
        <property type="entry name" value="DNJA1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001305">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43888">
        <property type="entry name" value="DNAJ-LIKE-2, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00684">
        <property type="entry name" value="DnaJ_CXXCXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="DnaJ/Hsp40 cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51188">
        <property type="entry name" value="ZF_CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="8">
        <location>
            <begin position="8"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="CR-type" evidence="9">
        <location>
            <begin position="141"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CR-type" evidence="6">
        <location>
            <begin position="141"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="386"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="106"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="406"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ25269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="422" mass="46492" checksum="4DA3B60DF44906D1" modified="2011-01-11" version="1">MSGEEDIDLYELLGIDKDASQDQIKKAYRKAALLHHPDKVPEDRREESEAKFKAVSQAYEILKDEDKRHLYDTHGMAAFDPSRGGPGGPGGVEVDLNDILSQMFGMGMGGPGGPGGGPRRPRRGPDEDQPYKVTLEELYKGKTVKFSANKQVVCGTCKGSGAKANVKPQQCEKCRGAGMTDAFRQVGPGLVRKETVICDRCEGSGNFYKEKDRCKKCKGKRTTSETKVLEIYIPRGSQNGERIVLEGEADQLPDQTPGDIVFHLAEEPHDEFTRIGNDLSAELNVTLAEALGGFSRTVLTHLDGRGIHIERPRGKILRPGDILKVPGEGMPHKRGDTKGDLYLIVNVEFPEDGWLKDDKEYDALNKLLPPPPPTIEADEVDEVEYEEVDSLDSMGANSGDPRFGGEWEDEEEDDGQPQCQPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2N3</accession>
    <name>E3Q2N3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00006</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ24862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008088882.1">
        <property type="nucleotide sequence ID" value="XM_008090691.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2N3"/>
    <dbReference type="STRING" id="645133.E3Q2N3"/>
    <dbReference type="GeneID" id="24405371"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00006"/>
    <dbReference type="eggNOG" id="KOG2084">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028281_6_1_1"/>
    <dbReference type="OrthoDB" id="265717at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053185">
        <property type="entry name" value="SET_domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332:SF6">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="145"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ24862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="460" mass="52080" checksum="439F27F90D272D79" modified="2011-01-11" version="1">MKASLVLLGAGSALAFRESKIMSSGSGEMCISSQLLAASSGEFVCRNNKDGSGLFYNDREDQQFPLAGTSSPFTSSPLSHSVWTHSTPCFKNSTDSPKFCIYHAGSYASGKGISIITEADRAAHITRSRGFTHPEDLEGTNQPLRKFQVAKVPGKDYGLVATLPIRRGEIILRETASLLIDYAAFTHIPPEDMRKLQAQAIDYLPFPHRGEWLNMSSHGYQGDHISMVDKILITNSFDVEMDDKRSDDFYAVFVNTSRMNHDCRPNVDYYFDPRTLTQRTVALRDIIPGEELTLSYIDPMQSREARRERLHSTWGFHCSCHHCTQHRLKTEESDRRIEQISALREEFNDYTPASRATPEMAQLLISLYEQEQHWGLLSEAYTLAAIEYNGVGEPWLATKYARLAVEAGLTTHWEGHGDVVEMSKLAEDPWSHWSWMLRTRKRYSWGGKPGRYDDDGDDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2W2</accession>
    <name>E3Q2W2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ecp2 effector protein-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00085</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ24941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008088961.1">
        <property type="nucleotide sequence ID" value="XM_008090770.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2W2"/>
    <dbReference type="GeneID" id="24405450"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00085"/>
    <dbReference type="eggNOG" id="ENOG502T4PJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093905_0_0_1"/>
    <dbReference type="OrthoDB" id="4788837at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029226">
        <property type="entry name" value="Ecp2-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14856">
        <property type="entry name" value="Hce2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180038" description="Ecp2 effector protein-like domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Ecp2 effector protein-like" evidence="2">
        <location>
            <begin position="147"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ24941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="294" mass="31274" checksum="D019F85C4855FE14" modified="2011-01-11" version="1">MAIMAGFLAVAVMALVVSANPESVPQGNGVIRDAACGSLCAFSEPQFDNAICYEVKLDNGKCKAVFVNSKAGKLDFNTTDDAIFAGIDVKRTQVDAGEGKSKGASATGDANKITKVHGATIGKGTATSTPITKRLFFDRSDMGEKVCDRQSSVCYDRGQMAKTQDCEELLLFWSKTHGKWVISDRDIAGRFWIELMASGSCVFAVGRPAAGIHINPTRDKETSLGDLDIVGILTQSIAGCGKSGKMEARGMIQCNAFDLVFWVVDKGSFDCCRGDKPPGKSIGKTWIAKSSGDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q386</accession>
    <name>E3Q386_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Urb2/Npa2 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00209</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089085.1">
        <property type="nucleotide sequence ID" value="XM_008090894.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3Q386"/>
    <dbReference type="GeneID" id="24405574"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00209"/>
    <dbReference type="eggNOG" id="ENOG502QTEB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_255115_0_0_1"/>
    <dbReference type="OrthoDB" id="160374at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052609">
        <property type="entry name" value="Ribosome_Biogenesis_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018849">
        <property type="entry name" value="Urb2/Npa2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15682">
        <property type="entry name" value="UNHEALTHY RIBOSOME BIOGENESIS PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15682:SF2">
        <property type="entry name" value="UNHEALTHY RIBOSOME BIOGENESIS PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10441">
        <property type="entry name" value="Urb2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleolar 27S pre-rRNA processing Urb2/Npa2 C-terminal" evidence="1">
        <location>
            <begin position="1157"/>
            <end position="1369"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1370" mass="152822" checksum="F03BA2B4D5CA6175" modified="2011-01-11" version="1">MDVEMTDANPSRPSETIISDRDLVKIVRSLDQTGPGANGENLERLWKQLTSASQSPFSAAEESVLRWLLKVMKANNDEAETIRRFPLTWRILGCAFQRIPLFSLAKSLADRKFMAVLQQTLKGVAKPSTEAETPASKSKKRKRTSTATFELQTLKSFEGCLGTGEAIFGVLKILLARLDSESQWSAHDRMGAEHIKALFAQPATEAVEYLSPLLLLCDYSLAAADTELFDSQESWVRVFSSSWELHLQGSVDALEVATHFSRTCISILGKIRQRPDFDDQVARLWTRDLDRFLQRNLVLPARSAYLNRNDLEVVFRALEMVKSNASVSVPILYSLVSSAPKVVGGLTTTKAEEAWMQEVFKLSERTIKRLPRDEKSQAMAAMLEEAITNKSCIALDDLRLVSNYAIVESPSETDWRLLSLIAKCDADVFLQSEESAQLFDQVCDRITDAGAKADEATMHELIESLIAGFENARDLSTFLQKWFSQLSKFEDKALRSGDRPVWFTRVHRHPTLIGGIEKSLTTKQIVGLLQWVDGQEILRPAAVFIFLDTIASAITRDDFADAAGNQLSDLTLKVWSSSKTPSDIRSLRWRIISKTASWLEYERATALWDKVQTDLTKALQKAKFDDEDTCEALGCAYHFWLSMYPDGRDQAELASLLTSFIERLLKKVKLEDLQGLFASQDFSSASTFDIPKFCSEFPLAASKLVLLLAKSSGTLPDYLQRIFSTTKDSDTQLENVLHAVLSNENNLSNRKLVGSVVDYTIEMISQVPSESFPWAEKRSRVAMVELSRVPDESFTRQQRERIMETMIPKLQAAGRVDLQDWHLVLGLLVKLMRRPTFYQNMSFSDLQNIAHSLAPLCDESDSRTALGLSQLLYQLAITTVRQMNDHQEWRTEYFVKVSALLKDLAGDASSVQMTLLKALLAIVLPDVSSKEKTAVFDIDATASALGSIVQDTLSNFAKAWRKQNITNALVNRVLIALDAAEALPEAVVEQLKVKVTQLEEASQQAISNGSFSGWKLQSFLIKRFPSKVANTRQTSFGQLFSTTLPAPMPSCPVPDPLSDFNRQTVLEDTVDAATADLDYNGKVQYVQNLLAGVQAEVAPQAGCSSEGQLLAIRRVVSHLAEAPAGREKTKTFDLSTAHGMLVRHLTQTKTVREFIRTAEVLQELLDVKANAMTQWNIETTLSTAAVIVADDPGHLLEASPSVYQWLCKLVEVVIKKHRLRLEGHYHILVTTLEALLSALARPSPQHSTPTPARAKHAAHFTRLVTLICEPAAAAVSRVQHLSALDSATDAAKRSAGRHMYLVLMAYVKMQLDVDIPRDVREALEPGMNSVFDITPLEVRKILNDSMDVSGRAILREMYKRYTKFGKWSGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3Q7</accession>
    <name>E3Q3Q7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_00803</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089679.1">
        <property type="nucleotide sequence ID" value="XM_008091488.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3Q7"/>
    <dbReference type="GeneID" id="24406168"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00803"/>
    <dbReference type="HOGENOM" id="CLU_1594395_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ25659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="167" mass="18312" checksum="64B02EF9DDB126CC" modified="2011-01-11" version="1">MTHLLKILSPQLRWISVRTEIAAHLLATLQTYASATVRNAQAVGRGLYAARRVSMATPGHSAQLQNLQGATPKPSAPVAQRLGAAKSALRQIDIALGIGLLPKTGMAERHPEIWRLRQRIAGLLMRYTYEKEFENQIRIALNKQGCRGKAHSKTIFRGIPAAGDRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3V3</accession>
    <name>E3Q3V3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Hemerythrin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00849</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089725.1">
        <property type="nucleotide sequence ID" value="XM_008091534.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3V3"/>
    <dbReference type="STRING" id="645133.E3Q3V3"/>
    <dbReference type="GeneID" id="24406214"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00849"/>
    <dbReference type="eggNOG" id="ENOG502SHZ8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066708_0_0_1"/>
    <dbReference type="OrthoDB" id="58416at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12108">
        <property type="entry name" value="Hr-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.520">
        <property type="entry name" value="nmb1532 protein domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053206">
        <property type="entry name" value="Dimeric_xanthone_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012312">
        <property type="entry name" value="Hemerythrin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38048">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38048:SF2">
        <property type="entry name" value="HEMERYTHRIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01814">
        <property type="entry name" value="Hemerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178186" description="Hemerythrin-like domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="Hemerythrin-like" evidence="2">
        <location>
            <begin position="63"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ25705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="298" mass="33327" checksum="5EAAC6AF5954CBF9" modified="2011-01-11" version="1">MAGYLLLVIPSILMSLLVSRAPFMMTTTPQTTRPWADGPMKLITTPQYETKKTDLFTLGSTHMALLHNSILRGYNSIYQQAPYIQEADKADFIGYSQTWYKFVKSHHDDEEESLFTKIENLLDDKNVFAETHKEHESFLGGLAEFNKYLTSLSSPSDFSGAKLLEIMKGFQEPFENHFHSEISTIAGLAAHPKAPKEGTPEAANASLTFKTWGKSTVTKAGTADVVPFFLLNLDRTAEDGLWSNWPPMPAPIKWGLINIAGAWHWGWWKFASCDAAGQPRELYALQSSGTEDKTKAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3V9</accession>
    <name>E3Q3V9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">amidase</fullName>
            <ecNumber evidence="3">3.5.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_00855</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a monocarboxylic acid amide + H2O = a monocarboxylate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:12020"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:35757"/>
            <dbReference type="ChEBI" id="CHEBI:83628"/>
            <dbReference type="EC" id="3.5.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amidase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.4" evidence="3"/>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089731.1">
        <property type="nucleotide sequence ID" value="XM_008091540.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3V9"/>
    <dbReference type="STRING" id="645133.E3Q3V9"/>
    <dbReference type="GeneID" id="24406220"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00855"/>
    <dbReference type="eggNOG" id="KOG1212">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009600_9_2_1"/>
    <dbReference type="OrthoDB" id="6428749at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004040">
        <property type="term" value="F:amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072:SF2">
        <property type="entry name" value="AMIDASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072">
        <property type="entry name" value="AMIDASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001221">
        <property type="entry name" value="Amidase_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="6">
        <location>
            <begin position="67"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="123"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="5">
        <location>
            <position position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ25711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="520" mass="56697" checksum="AF16708D401747C1" modified="2011-01-11" version="1">MIGSEHPADKAWSWTEVAAAKRAARDAQLGKYELTDGVSSSATLGADEVDIETLMDLLRSGQVSAEELIRAYIERACKAQSKTNCLTETCFDDAIERARELDGFRQTHGRMIGPLHGVPISVKDQVNVKGLASTLGYVSNAFTPAKEDAPLSRHHVLTNVWWCETNNPLWGLTTHPANSKLTPGGSSGGEAALLSLGGSLIGWGTDIGGSIRIPSHMNGLWGLKPSSRRLSYRGVMNSMEGQQYVPSAIGPMARSLSSLTAVTKLVIEAAPSTTDPQIPPLPWRDDAFQEASSRSLVVGTMLDDGVVKVHPPIERVFRALATKLQAAGHELVEWDTSLNEECIKILHECYSADGGEDIRHAVAEGVEPLMSGVQEFVDLGPAITVYQYWQLNKRKVAMQQSYHDMWNGARSPSGRPVDVLLVPTMPHTAVPHGSCRWLGYTKLFNLLDYTALTFPAGRASRKLDGDTPPHHTPRNADDAWNWGLYDPVAMDGLPVGLQLVGRRFEEEKVLGAAQQIQRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q400</accession>
    <name>E3Q400_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7730 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00896</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089772.1">
        <property type="nucleotide sequence ID" value="XM_008091581.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q400"/>
    <dbReference type="STRING" id="645133.E3Q400"/>
    <dbReference type="GeneID" id="24406261"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00896"/>
    <dbReference type="eggNOG" id="ENOG502T62E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_860550_0_0_1"/>
    <dbReference type="OrthoDB" id="5397846at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056632">
        <property type="entry name" value="DUF7730"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38790">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24864">
        <property type="entry name" value="DUF7730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7730" evidence="2">
        <location>
            <begin position="47"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ25752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="323" mass="37789" checksum="78D9AE1FD0DA8594" modified="2011-01-11" version="1">MSSPLNTAKGGSRRPMKRKSRATSSTPRAKKQRIEPEQLGPFLFLLMFRSLPPEIRNIVYELAFFRPAGIDLAGRNESYTVKSSKFLWQRKDVRHVREQTRRGNPNDKIPVSFLKCCKRVHSEARTILYANRFRVGDMETLAVWLRDLSPGNIVYLRWIQIRTEPQPWTSRVSRRVVAQHSRYRDVCRKVAKMIAVARSLESLQTVFHYHHKIKSQRSSLQRRGPVSGWIDLARKVADLVYDDFRPIFSQGLSRGRSPEQLCRILGVGQNNWWGRRRSLTPSQLNATDAEHAENEVAEHLRLLLERNLQHRHRFPHKRQELDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4N8</accession>
    <name>E3Q4N8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_01197</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ26053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090073.1">
        <property type="nucleotide sequence ID" value="XM_008091882.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4N8"/>
    <dbReference type="STRING" id="645133.E3Q4N8"/>
    <dbReference type="GeneID" id="24406562"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01197"/>
    <dbReference type="eggNOG" id="ENOG502SQIV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2249924_0_0_1"/>
    <dbReference type="OrthoDB" id="5390143at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180050" evidence="2">
        <location>
            <begin position="24"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ26053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="104" mass="11091" checksum="2445FF03BE18823B" modified="2011-01-11" version="1">MHLLAAVLLLGGLLPRLPAGARAEDSFRHPPGPGPTGDYRDNPVYAVGDSVDLQWETTLESADLALCQGKPGGDDDARPACATIVGELSGFLFFSPLLPWFRED</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q524</accession>
    <name>E3Q524_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_00935</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089811.1">
        <property type="nucleotide sequence ID" value="XM_008091620.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q524"/>
    <dbReference type="STRING" id="645133.E3Q524"/>
    <dbReference type="GeneID" id="24406300"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00935"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_0_1"/>
    <dbReference type="OrthoDB" id="1669814at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24321">
        <property type="entry name" value="DEHYDROGENASES, SHORT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24321:SF8">
        <property type="entry name" value="ESTRADIOL 17-BETA-DEHYDROGENASE 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ25791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="255" mass="26408" checksum="D932EBEBF5F564E2" modified="2011-01-11" version="1">MGSLKGKVIAITGAASGIGNATARHIASLGARVSISDVNEELLSSVTTELTGLYGAENVYSKIVDVRDRKAVDAWIAETVEKLGPLDGAANVAGVLGRQGNKANVTEIEDDEWDFVMGVNARGVLNAMRAEILSMGDGVRGKSIVNVASVAGHYGLEFHGAYTASKHAVVGLTKSAAREFGRKGLRVNAICPGAIDTPILRKAMETAGTGADVFPALLGRIGEPMEIATAITFLLGDEASYVTGQAWLVDGGSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5L6</accession>
    <name>E3Q5L6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_01127</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090003.1">
        <property type="nucleotide sequence ID" value="XM_008091812.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5L6"/>
    <dbReference type="GeneID" id="24406492"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01127"/>
    <dbReference type="eggNOG" id="ENOG502REFV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1004770_0_0_1"/>
    <dbReference type="OrthoDB" id="5538558at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ25983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="316" mass="34961" checksum="CC9BDE75864EAA6A" modified="2011-01-11" version="1">MQATRLLSQQAAAPLVRRVIPNARRGHAPLRHLKLLNPESAVPTPKPRLRAGRDLLQRIGKCLAFGCNPQQTADAAAVVRTVVNDWARIEMTLSKCGTQEDLVYKQTLLRPGDEASLATPEPTWKVFGQRQQLSQVACQATMHLLNHAIATAAPDRKWIWHALRAGDITGSPGRLAVDATRLRFQPVRLPLDIITGSGEELGSHSAYARLLTYSLFSDRACLTFKVYIRSNIRMAVIADGFVQMSTSFNQATPDAISSLKQELGRMTAFQHDRDTQNRARIQHAELLNAIEKLENETWNRDDAVEDFGSASPASPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5Q7</accession>
    <name>E3Q5Q7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">F-actin-capping protein subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_01692</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 10">F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the F-actin capping complex, composed of a heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Actin patch</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the F-actin-capping protein beta subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090568.1">
        <property type="nucleotide sequence ID" value="XM_008092377.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5Q7"/>
    <dbReference type="STRING" id="645133.E3Q5Q7"/>
    <dbReference type="GeneID" id="24407057"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01692"/>
    <dbReference type="eggNOG" id="KOG3174">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045864_1_0_1"/>
    <dbReference type="OrthoDB" id="9979678at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099079">
        <property type="term" value="C:actin body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000142">
        <property type="term" value="C:cellular bud neck contractile ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005934">
        <property type="term" value="C:cellular bud tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008290">
        <property type="term" value="C:F-actin capping protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000131">
        <property type="term" value="C:incipient cellular bud site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043332">
        <property type="term" value="C:mating projection tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031097">
        <property type="term" value="C:medial cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044396">
        <property type="term" value="P:actin cortical patch organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051016">
        <property type="term" value="P:barbed-end actin filament capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030447">
        <property type="term" value="P:filamentous growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904600">
        <property type="term" value="P:mating projection actin fusion focus assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903475">
        <property type="term" value="P:mitotic actomyosin contractile ring assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902404">
        <property type="term" value="P:mitotic actomyosin contractile ring contraction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.570:FF:000001">
        <property type="entry name" value="F-actin-capping protein subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.210:FF:000005">
        <property type="entry name" value="F-actin-capping protein subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.210">
        <property type="entry name" value="F-actin capping protein, beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037282">
        <property type="entry name" value="CapZ_alpha/beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042276">
        <property type="entry name" value="CapZ_alpha/beta_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001698">
        <property type="entry name" value="CAPZB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043175">
        <property type="entry name" value="CAPZB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019771">
        <property type="entry name" value="F-actin_capping_bsu_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10619">
        <property type="entry name" value="F-ACTIN-CAPPING PROTEIN SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10619:SF0">
        <property type="entry name" value="F-ACTIN-CAPPING PROTEIN SUBUNIT BETA ISOFORMS 1 AND 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01115">
        <property type="entry name" value="F_actin_cap_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00192">
        <property type="entry name" value="FACTINCAPB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90096">
        <property type="entry name" value="Subunits of heterodimeric actin filament capping protein Capz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00231">
        <property type="entry name" value="F_ACTIN_CAPPING_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0117">Actin capping</keyword>
    <keyword evidence="6 10" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="5 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ26548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="267" mass="29713" checksum="2C9DE3B20DB0C274" modified="2011-01-11" version="1">MASVDPFDSALDLLRRLNPKHTTEHLNAIISLAPDLTEDLLSSVDQPLTVKRCKQTGRDYLLCDYNRDGDSYRSPWSNQFDPPLDEGAIPSERVRKMEVRANEAFDVYRDLYYEGGVSSVYFWNLDDGFAGVVLLKKSATPGGSAEGIWDSIHVFEAIERGRTTQYKLTSTVILSLSTSTGALGDMDLSGNMTRQVEQELPVEGDESHIANVGRLVEDMELKMRNLLQEVYFGKAKDVVGDLRSIGSLSEGAKDRAAQREIIGSMQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q658</accession>
    <name>E3Q658_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Superoxide dismutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_01450</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.</text>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090326.1">
        <property type="nucleotide sequence ID" value="XM_008092135.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q658"/>
    <dbReference type="STRING" id="645133.E3Q658"/>
    <dbReference type="GeneID" id="24406815"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01450"/>
    <dbReference type="eggNOG" id="KOG0876">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057349_1_0_1"/>
    <dbReference type="OrthoDB" id="275227at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.40.20">
        <property type="entry name" value="Iron/manganese superoxide dismutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019832">
        <property type="entry name" value="Mn/Fe_SOD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036324">
        <property type="entry name" value="Mn/Fe_SOD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036314">
        <property type="entry name" value="SOD_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43595">
        <property type="entry name" value="37S RIBOSOMAL PROTEIN S26, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43595:SF2">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02777">
        <property type="entry name" value="Sod_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54719">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46609">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Manganese/iron superoxide dismutase C-terminal" evidence="2">
        <location>
            <begin position="217"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00037226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ26306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="284" mass="31197" checksum="D50423E71A06A1CA" modified="2011-01-11" version="1">MFARLRIPRVGATIAAAASAPARTTTMQMQQRSLHSVPQLAHDFKHGVPGLLSADGYDMAWNQYMTVILDKLNALIAGTDFEQRDVKQILLATAQDPSQAPIFNHASMAHNTHFFFKNITPNPKPMPESLVSELSHSFSSIETLRREMILTASAMFGPGFVWLIKAGHQDYRVLTTYLAGSPYPGAHWRLQGTDMNTVGAGGSASNYFQRSAAAQRPGQKPPGALDAIPLLCLNTWEHTWLRDYGLGVGGVGGKKAFAEAWWEVIDWNAVHTAADIPTRPNFVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7T9</accession>
    <name>E3Q7T9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_02122</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ26951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090971.1">
        <property type="nucleotide sequence ID" value="XM_008092780.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7T9"/>
    <dbReference type="GeneID" id="24407487"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02122"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_5_1"/>
    <dbReference type="OrthoDB" id="6730379at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000064">
        <property type="entry name" value="MFS allantoate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF73">
        <property type="entry name" value="TRANSPORTER, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="134"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="227"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="296"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="331"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="359"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="385"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="420"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="452"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="67"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="498"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ26951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="545" mass="60202" checksum="E942591C283F7835" modified="2011-01-11" version="1">MASATPAAKQAGGLNSDTIESVPKTEPAPAGALKEKAAQFLAAHGGGDTSFTYEEEKAVLKRINLRVLPLVLGAYFFQQLDKSTLSYVSVFGFQEDANLHGRQYSWLGSILYIAQLVWQPAAAYILVKLPNGKVIAAAIFLWGSSLAIMTSCTNFGALLGLRFMLGTFEAMIAPSCLAVTTTWWRRSEQTLVTSSWNAMNGVTFIIGSLFTYGLGHIESDKLYKYQIIFLFCGLLTVSYAFVVLVLMPDSPMSAKYLTEREKVIAVERLRANQMGIQSGVWRWDHVWETFVDLKTWCWFVIVIAISIASGGISTFGNLIVKSFGYSSFQTILFNIPFGVIQIIAIMGSGWIATRTQRKGLVIAGIAIIPAIGTVIMLTVPRQHKGVLLFGYYLVSALAAITPLIYTWQAQNTAGDTKKKTTSAVVFIGMCTGNIIGPLLYSVDDAPVYRPGLISNLVMFILVAFMGALLPLYLKYLNVQHAKRREALGKSSDIVDESMMRNKDGKDSKEVELEEDPQRQQRKAIEEDHGLQDMTDLKNEDFIFVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q877</accession>
    <name>E3Q877_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Store-operated calcium entry-associated regulatory factor</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Transmembrane protein 66</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">GLRG_02260</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SARAF family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091109.1">
        <property type="nucleotide sequence ID" value="XM_008092918.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q877"/>
    <dbReference type="STRING" id="645133.E3Q877"/>
    <dbReference type="GeneID" id="24407625"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02260"/>
    <dbReference type="eggNOG" id="ENOG502QT6Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046802_1_0_1"/>
    <dbReference type="OrthoDB" id="20303at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006816">
        <property type="term" value="P:calcium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001256">
        <property type="term" value="P:regulation of store-operated calcium entry"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009567">
        <property type="entry name" value="SARAF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15929">
        <property type="entry name" value="STORE-OPERATED CALCIUM ENTRY-ASSOCIATED REGULATORY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15929:SF0">
        <property type="entry name" value="STORE-OPERATED CALCIUM ENTRY-ASSOCIATED REGULATORY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06682">
        <property type="entry name" value="SARAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 16" id="KW-0732">Signal</keyword>
    <keyword evidence="6 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179509" description="Store-operated calcium entry-associated regulatory factor" evidence="16">
        <location>
            <begin position="22"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="156"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="184"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="261"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="14">
        <location>
            <begin position="203"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="282"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EFQ27089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="317" mass="32685" checksum="2B4CC22E46097956" modified="2011-01-11" version="1">MHCPLVLGLGLIPLLPGLASAAKVPKNAILLSEVQSLTLRGGGAKTTHRRVAAAPQLKCLSSKAICDLHDIDVMRCTNQGAGYSSEDIQWSCVASLPEELKLGSTDVICEGYASSDDPYILRGSCGVQYRLALTDKGERRYPNLGKGEDGDGESDWGAYLFGIIFVGVLAWIVYSACVAGAQNRRPGGNGRPPESALQNLVGPCGGPGGGGGGWDPGFGQDDDPPPPYPGTKPTNQGGQQGWRPGFWTGAGAGGAAGYGAGYYHGRNSARNQSGYGTGGWGNDSSSSSWGAGPSRSNSSSSSSARHDSTGFGSTSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8S4</accession>
    <name>E3Q8S4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_01933</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091458.1">
        <property type="nucleotide sequence ID" value="XM_008093267.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8S4"/>
    <dbReference type="GeneID" id="24407298"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01933"/>
    <dbReference type="eggNOG" id="ENOG502SHTF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_636167_0_0_1"/>
    <dbReference type="OrthoDB" id="3540210at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="325"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="431" mass="48522" checksum="D706C5A5490C6C76" modified="2011-01-11" version="1">MGSRSFGMKTELIDSHKHLGINQPLYNRVYYRRETECSPLITQRGFSRFVNGSETQEFGWDDNVLIKYFYGNVNFNNYTYIYNTYGESMKSGYSTWSIHALAGNNGTIWQPAEALFLDHRDVTLLLIAPNSVIHIEQNDDAVFGASIPIELSDGATVYRPDRYVSPIACADRHRICNPNNGICTTPQGGTETVRNARGKDIDLNPVQLATVDRMGLHFAASTFQHLIWTRTQSFLKAQELVADLTQLPLPSNQWQIEMASLFADNLSKMQHYMLEYVTGPSLVVEGTIERTWDSAGSSSRAQEDYRAAQEDMCHRQKIKSSQGTINFSVVGLSLLLGLGSLFIGFSYLLESITQVLQRITGLGVRKAKRWERDENLQVMRMLFELNGAGTWKGSTDCFPTTESKDAFEYDCGLRGRGPQYSAIVHEHNGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q920</accession>
    <name>E3Q920_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mitochondrial distribution and morphology protein 35</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_02029</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRIAP1/MDM35 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091554.1">
        <property type="nucleotide sequence ID" value="XM_008093363.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q920"/>
    <dbReference type="STRING" id="645133.E3Q920"/>
    <dbReference type="GeneID" id="24407394"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02029"/>
    <dbReference type="eggNOG" id="KOG3481">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101473_2_0_1"/>
    <dbReference type="OrthoDB" id="19091at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990050">
        <property type="term" value="F:phosphatidic acid transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007918">
        <property type="entry name" value="MDM35_apoptosis"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46403">
        <property type="entry name" value="TP53-REGULATED INHIBITOR OF APOPTOSIS 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46403:SF1">
        <property type="entry name" value="TP53-REGULATED INHIBITOR OF APOPTOSIS 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05254">
        <property type="entry name" value="UPF0203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ27534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="83" mass="9672" checksum="B4879871EB4D4F68" modified="2011-01-11" version="1">MSASLAPECNEVKERYDTCFLKWYSEKYLRGTGTDNNECADLFKNYQKCLTVALKERGIDKLLDEAREDQKDNDATYMGRKCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9G0</accession>
    <name>E3Q9G0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Fumarylacetoacetase</fullName>
            <ecNumber evidence="3 13">3.7.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Fumarylacetoacetate hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">GLRG_01834</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>4-fumarylacetoacetate + H2O = acetoacetate + fumarate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10244"/>
            <dbReference type="ChEBI" id="CHEBI:13705"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18034"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="EC" id="3.7.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="13">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 13">Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the FAH family.</text>
    </comment>
    <dbReference type="EC" id="3.7.1.2" evidence="3 13"/>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091359.1">
        <property type="nucleotide sequence ID" value="XM_008093168.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9G0"/>
    <dbReference type="STRING" id="645133.E3Q9G0"/>
    <dbReference type="GeneID" id="24407199"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01834"/>
    <dbReference type="eggNOG" id="KOG2843">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026207_2_0_1"/>
    <dbReference type="OrthoDB" id="9971669at2759"/>
    <dbReference type="UniPathway" id="UPA00139">
        <property type="reaction ID" value="UER00341"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004334">
        <property type="term" value="F:fumarylacetoacetase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902000">
        <property type="term" value="P:homogentisate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006572">
        <property type="term" value="P:L-tyrosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.230:FF:000001">
        <property type="entry name" value="Fumarylacetoacetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.850.10:FF:000009">
        <property type="entry name" value="Fumarylacetoacetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.230">
        <property type="entry name" value="Fumarylacetoacetase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="entry name" value="Fumarylacetoacetase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005959">
        <property type="entry name" value="Fumarylacetoacetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015377">
        <property type="entry name" value="Fumarylacetoacetase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036462">
        <property type="entry name" value="Fumarylacetoacetase_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01266">
        <property type="entry name" value="fum_ac_acetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43069">
        <property type="entry name" value="FUMARYLACETOACETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43069:SF2">
        <property type="entry name" value="FUMARYLACETOACETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09298">
        <property type="entry name" value="FAA_hydrolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="FAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63433">
        <property type="entry name" value="Fumarylacetoacetate hydrolase, FAH, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12 13" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 12 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 13" id="KW-0585">Phenylalanine catabolism</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 13" id="KW-0828">Tyrosine catabolism</keyword>
    <feature type="domain" description="Fumarylacetoacetase N-terminal" evidence="15">
        <location>
            <begin position="19"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="Fumarylacetoacetase-like C-terminal" evidence="14">
        <location>
            <begin position="136"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="363"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR605959-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR605959-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR605959-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU366008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF09298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EFQ27339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="432" mass="46928" checksum="3A65D70A74E73EFD" modified="2011-01-11" version="1">MSSSQSWVPVSPTSHFSLANIPFGIISSKSDPTHRPAVAIGDHALDLKAFANAGGFDALPSIHKHISVFSSPTLNEFAALDRPVHRQVRAYLQSVLSDSTPHAGLLKDNADMRQAAILPFSEVRNHLPMAIGDYTDFYAGKNHAYNVGVLFRGPDNALQPNYVHLPVAYHGRASSVVVSGTPIRRPWGQILRDPKAEPKVPALAPCERLDIELELGMFVCRENNLGEPVPVDQAEEHIFGYVLMNDWSARDIQAWEYVPLGPFTSKNLGTSISPWVVLADALAGAKTAGLENKTELLPYLRESRKDNTLDIELEVEIITASGNKTTLSRTNSKNLLWSWPQMIAHHTITGCNLRPGDMFGSGTISGADPGTEGSILEQTKGGKQAVKLNGGEERKFLQDGDTVIIRGWSGQKGAIVGFGEVSGQIEAPLKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9H1</accession>
    <name>E3Q9H1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Fungal specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_01845</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091370.1">
        <property type="nucleotide sequence ID" value="XM_008093179.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9H1"/>
    <dbReference type="GeneID" id="24407210"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01845"/>
    <dbReference type="eggNOG" id="ENOG502SIME">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012331_3_0_1"/>
    <dbReference type="OrthoDB" id="189997at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052202">
        <property type="entry name" value="Yeast_MetPath_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782:SF12">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="47"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="115"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="213"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="654"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="739"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="136"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="220"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="674"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="745"/>
            <end position="755"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ27350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="794" mass="87022" checksum="AAEFE32E215B3E4E" modified="2011-01-11" version="1">MFDEVSLSRPAAPTSASHRESPVSPGTGPTIAGSHMPPSRKQRVALACKRCKRRKQRCDGAHPSCNSCRKANSECVYERALRPHYPGGKSLYISALEERIAFLEARMPDYAEDHFASTSAATPAPPPAPAPAQEAKSPRRESRDSCSEDEPTSLVDGVAYLSLCASGTTDTAPEPFYLGSSSGATIARMIQSAIFHGAAGRAALSEAMAAAPAGVLSPPRSRNSVSASSHPDEPMSEFPYPSESKMLFDVFFDRLHTRWPILDRQLYTTLFEQQYDQGALSIQHRSIMHLVYAISARFLQLMKKPCDVDPQQHLMAAIEPMDYILEQHNLATVQFLLLLAVHGTRSPYGAGAWSQIRYAVTLCIELGLHRKQTTASSHSARDLEIRRRAFWSCYCLDRMTSVVLGRTFAIADRDINVELPSDSTEFWDLTALGSPPAGQKPVWSNVEPFIHIIKLRRIQSRIHRRVYRVDRDVFTSSPEERSKLDTKMAAIRAELDEWARSIPHPPKDAAGITWMYDPESAYHDSRDFFNLQYHKSILSLFTVLLPTVSTSDARFVTTARSAACVCTAYKRLNQQKTLSYTMTALHSCFIAGLTLVYCLWRDRALFSYDALEATHACSQSLTIFGEKWPGAVKYRDIFDALSGSLFKTIVDPRAESAAPGPKPLKVDFAAEPVGSPTAPSAAAATASSDGGGGRRGSGAEERCAVGDAISDAVKEAFMEVDEEAPGGWQGWRMFNEMVQSDLAPSGPPPPPPPPQAGSWDVLAQDAVSIHDLGQGGVSDVMDSEWDFGGLEGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9J5</accession>
    <name>E3Q9J5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_01869</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091394.1">
        <property type="nucleotide sequence ID" value="XM_008093203.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9J5"/>
    <dbReference type="STRING" id="645133.E3Q9J5"/>
    <dbReference type="GeneID" id="24407234"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01869"/>
    <dbReference type="HOGENOM" id="CLU_2542438_0_0_1"/>
    <dbReference type="OrthoDB" id="4850545at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ27374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="83" mass="9686" checksum="AC13519462C2A293" modified="2011-01-11" version="1">MKYSGEMYDVFDLKLNIFRHTCSKAGIEEHQLAPIFSIMLRAQAVTFYFSRVCGSSIRDFVEIVQPVRSHFEIQESTQTYLTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9L9</accession>
    <name>E3Q9L9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">GPI inositol-deacylase</fullName>
            <ecNumber evidence="12">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">GLRG_02701</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 12">Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the GPI inositol-deacylase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="12"/>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091577.1">
        <property type="nucleotide sequence ID" value="XM_008093386.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9L9"/>
    <dbReference type="STRING" id="645133.E3Q9L9"/>
    <dbReference type="GeneID" id="24408066"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02701"/>
    <dbReference type="eggNOG" id="KOG3724">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006103_1_0_1"/>
    <dbReference type="OrthoDB" id="348976at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050185">
        <property type="term" value="F:phosphatidylinositol deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006505">
        <property type="term" value="P:GPI anchor metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000056">
        <property type="entry name" value="GPI inositol-deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012908">
        <property type="entry name" value="PGAP1-ab_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039529">
        <property type="entry name" value="PGAP1/BST1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056824">
        <property type="entry name" value="PGAP1_TMD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15495:SF7">
        <property type="entry name" value="GPI INOSITOL-DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15495">
        <property type="entry name" value="NEGATIVE REGULATOR OF VESICLE FORMATION-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07819">
        <property type="entry name" value="PGAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25141">
        <property type="entry name" value="PGAP1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25140">
        <property type="entry name" value="PGAP1_TMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="197"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="867"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="913"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="964"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1046"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1086"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1154"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="domain" description="GPI inositol-deacylase PGAP1-like alpha/beta" evidence="14">
        <location>
            <begin position="271"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="domain" description="GPI inositol-deacylase transmembrane" evidence="15">
        <location>
            <begin position="872"/>
            <end position="1189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="32"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="92"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU365011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF07819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF25140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EFQ27557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1218" mass="136083" checksum="E79C1C123A9FEF31" modified="2011-01-11" version="1">MKRRSSGSTDDSDEPPHPDPPAIRLQHHHYQYQHGQPSPDCNFASPPPPSPPSRAPKQSAIVAAVAVASRPSSARSRRSNNPNWKLEHGPNANGSPENHSLTASSLPPPFSSVSLTAPSPTYRNDHRQLPNHTHSQAPGAERQTHQEDVVSLPNVQDDDDDDDDNSSRDESMATASEKMPDVRFAGRRPRSRSPWSITIFALAVTVLGITLLCAILNSSWTRQIDAKGCRMSYMRPSYIRLRDFDTEHTRFATKYSLYLYREQGVDDERKLRGIPVLFIPGNAGSYKQVRPIAAEAANYYHESLQHDEIAAATGTRSLDFFTVDFNEDITAFHGQTMLDQAEYLNEAIRYILSLYMDPRMSARDHGLPDPTSVLVLGHSMGGIVARTMLIMPNYQSNSINTIITMSAPHSRPPVTFDGQIVKIYDDINDYWRHAYSQKWANNNPLWHVTLVSIAGGGLDTVVPSDYASVESIIPETHGFTVFTTGIPGVWTSMDHQAILWCDQFRKVVARAMYDVVDVHRSSQTKPRAERMRVFKKWFLTGMESIAEKTLPSEGLSTLLTLEDNSNAIMAQGERLVLRQLGREPKPRAHLLPVPPQGSPESKRFTLLSDTALDKPGEHGKLEVLFCSVFPLQPGQATTLFSMNMDLSGDSTGSTRLACKSAAPDVILLPPSTESRHEPFSLDNDPVTRPFSYLQFDTEDISDHQFVAVVDKAVKPTRSFVVAEFSDYSQSHRRRNISLRRLLAFGMTLSLPSNRSMVAEINIPTLQSSLLAYSLEMANQACGTTSGLFSPMIRQHLAQPYESKFFVNARHASISMHGVAPFVPPPLRHKGHDEQGLSLQFWTDPTCESAIQVKLTVDVLGSLGKLYMRYRTVFAAFPLLVVTLVLRKQFRVYDTTGTFISFSEGLDLCLRQSLPLMLLSLTFLSLSMTGSWSSGPGVFWHWRNTTSTAADFHSNDLLTGTQDPFFWFLTPLIGVVCIGVCAVLHYVTLALTQLLGIAYSRLALRPYGQARDERRRAQLPAFVASSPRRRMVTTAVLLFLVSTFIPYQFAYLVACLVQLFTAVRALRIASELKSGPTFAFYHYAHSILLLMLWVLPINLPILAVWIRNLAVHWLTPFSSHHNVLSIMPFILLVENLTTGKMVPRVSGRMRHLTSVLLFGTAIYAAIYGVSYAYMLHYLVNLIAAWLVVVHSTNDNWPLAGFSSIFENSHVEDRKRGKTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9X8</accession>
    <name>E3Q9X8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02810</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091686.1">
        <property type="nucleotide sequence ID" value="XM_008093495.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9X8"/>
    <dbReference type="STRING" id="645133.E3Q9X8"/>
    <dbReference type="GeneID" id="24408175"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02810"/>
    <dbReference type="eggNOG" id="ENOG502SD0J">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_386840_0_0_1"/>
    <dbReference type="OrthoDB" id="5404004at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="447"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="586"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="660"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="486"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="514"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="588"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="721" mass="78073" checksum="EF0D7E7647A37150" modified="2011-01-11" version="1">MSKLVNRSRSMKSMRIGEGAPGVAPRTHGPESFVLRSPGLVSSFQQTKKDSGVSQNEVLPFFAVDAAAVVQTRHTYSHRPLPTPPRSKASSTMAERPRTSGGPSPHNYSAASFKNFDKRVSKDDMYIRPHSSARGGYKSYHIPIRDNPASPIESPGDFSYDYSPARTFTVRTQTPDSMDSNMGTIAIGMAIGSPTHPPPQFSASSEFAASSEFLTTSVSATRSDWQPQSSGMSTSMVMASPEPPQETSEPAPAPKQKSGRWKLFGRSKSKRLASSPVTISQPMNLQQPSASRTDFEKFPTTNPASDLGRRNTERKPAESKPPMLRSQTAGPTAPPSPKDAKAPKLLSRMASTRSARSVKKSDISGPVHVSMAVPVMPPKPSASPKPPGGFLDVEIPSIKMERYSVMFGNVLGQPREVQASTSGQQALHSSSSLLERRQATLDRLKTISDQIANGERNRGRAKGRRATSPQPPESPAFSLSLFPATPSESANRPPQSPRYRSNTSPAYISSTQRAKVELAKTHPESTRRKTPSPETSGNRPRRPREPAAHEVVTGPKQGSFANNDEPEEIHLTEQLKPTIYEPPWQMVAPAASTAPSSAAPSAKDRSPTPVSPVQTHVTKPSFDGSEPDDALRAAVEISIARQISISRQQRQMLRPMKPNAVRIGGANSPRTKSPVPPIAVGKNERLSSTKSSTPTLICPGETFEQQIAQNRKSERIIVEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAC7</accession>
    <name>E3QAC7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SprT-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_02959</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091835.1">
        <property type="nucleotide sequence ID" value="XM_008093644.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAC7"/>
    <dbReference type="GeneID" id="24408324"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02959"/>
    <dbReference type="eggNOG" id="ENOG502T8ZG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090705_0_0_1"/>
    <dbReference type="OrthoDB" id="5236983at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ27815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="182" mass="20182" checksum="7FA559B6DEF87986" modified="2011-01-11" version="1">MKAIDELCLLGLLFPTSQINHVSHPVLVEVGQARGRVGWTQPLRGHKSSGGPSIAIRLSTVRYHPNGTRTQLPLKELVQIAVHEMVHAYLILFSCRRGQCEVDFDVMHRNADGGGHGLAFVALLKAVVCQIQSWAPGLGDFGLTDEAIHPYEDFGLELWKRGDRVSSRGKGQRVWWLAARPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAD2</accession>
    <name>E3QAD2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SprT-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_02964</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091840.1">
        <property type="nucleotide sequence ID" value="XM_008093649.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAD2"/>
    <dbReference type="GeneID" id="24408329"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02964"/>
    <dbReference type="eggNOG" id="ENOG502T6IQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061207_0_0_1"/>
    <dbReference type="OrthoDB" id="5236983at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ27820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="308" mass="34584" checksum="8FD2B1E77888ADEA" modified="2011-01-11" version="1">MTCGHFLHCELQPHQTAARDAFVKCYLEASPRGTAWDKLPAQRVQSFEEGSGSKLDEAEGAFLEGSLRSMMKYLDEYFFFGTMTRLQEGQQYLLLALETGFGRLKADVAEGRYGDTQIYRTHWDNTDQPYARVRLWSRLACDSPQSRDGGRRIRRLSFARNVATLIHELVHAYLGIFVCAGAQCRRNILNTTGVTGHASTFTKLYALVLGEVREWHPELGSLNKHECIPGTSIVSHNIAFEAAARQQWRSDGRDRGLLPLRADSPRNLVRQTEEVINGISVMSITYRRPGSRIPGQEEADGSCDVDGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAJ4</accession>
    <name>E3QAJ4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Splicing factor YJU2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_03026</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the spliceosome. Present in the activated B complex, the catalytically activated B* complex which catalyzes the branching, the catalytic step 1 C complex catalyzing the exon ligation, and the postcatalytic P complex containing the ligated exons (mRNA) and the excised lariat intron.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the CWC16 family. YJU2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ27882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091902.1">
        <property type="nucleotide sequence ID" value="XM_008093711.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAJ4"/>
    <dbReference type="STRING" id="645133.E3QAJ4"/>
    <dbReference type="GeneID" id="24408391"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03026"/>
    <dbReference type="eggNOG" id="KOG2989">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053603_1_0_1"/>
    <dbReference type="OrthoDB" id="674963at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071006">
        <property type="term" value="C:U2-type catalytic step 1 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000349">
        <property type="term" value="P:generation of catalytic spliceosome for first transesterification step"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03226">
        <property type="entry name" value="YJU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007590">
        <property type="entry name" value="Saf4/Yju2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043701">
        <property type="entry name" value="Yju2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12111">
        <property type="entry name" value="SPLICING FACTOR YJU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12111:SF1">
        <property type="entry name" value="SPLICING FACTOR YJU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04502">
        <property type="entry name" value="Saf4_Yju2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="11"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="234"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="114"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="238"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="254"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ27882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="300" mass="33973" checksum="7AB2B99318CAE03F" modified="2011-01-11" version="1">MSERKVLQKYYPPDFDPSSLTRKRGPKQTGPKVQTVRIMAPFSMKCTTCGEYIYKGRKFNSRKETNQAERYLNIQIHRFHIKCTRCSAEIIFRTDPKIADYAVVKGALRNMEPWRNKEGEKESVDERLDRLEREEAEAAGEEEKNAMADLEAKNEDARREMAAADALDEIRQRNARIQRSEKDGIDFSEYVVRPEDEEKARLEREDEEAARRAFAAARERASLMDLGEEIIDDDGDVAEAGVNGDAATSSGSGDRTETAEARAVRDTSTMPPPPPPVKRVVKKKKDYSAALGIKKKPSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAN2</accession>
    <name>E3QAN2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyoverdine/dityrosine biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_03064</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ27920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091940.1">
        <property type="nucleotide sequence ID" value="XM_008093749.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAN2"/>
    <dbReference type="STRING" id="645133.E3QAN2"/>
    <dbReference type="GeneID" id="24408429"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03064"/>
    <dbReference type="eggNOG" id="ENOG502QRI9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025510_0_0_1"/>
    <dbReference type="OrthoDB" id="429813at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007817">
        <property type="entry name" value="Isocyanide_synthase_DIT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37285">
        <property type="entry name" value="SPORE WALL MATURATION PROTEIN DIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37285:SF5">
        <property type="entry name" value="SPORE WALL MATURATION PROTEIN DIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05141">
        <property type="entry name" value="DIT1_PvcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="518"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="524"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="577" mass="64221" checksum="265B86C670031BDE" modified="2011-01-11" version="1">MEFSNSGDSVFHRFQAAFVHDGQGQLLYCTGPQKGRVQEHWEVINRHLPSRSQTATGESQKAGSADLDGPLRGSRLYEMRRPGSGPTGLILDASSQNSNTPSTQFEEFFAQLLLDQADFAIRDFGLMKSPSGASLAVTEQIVDLFDSFLRYQGKDDRWEVCGKAYFTERVRHFTSQNASIELCLPAFPCKSSNTNKVLGKAPDRGERLALERLHSFVEAIEKMYQPGAKMWIISDGHVFSDCIGVDDADVDMYGEKLKEMNRAIGISRGNTDRVGFRSLVDLFELDRARSQYKLSALQTQLSILNIEHHVETRLTVEAELCRQILMAGCQPQESAVRAKIKSQNATILALYRGFSRFMLEDLELHPHTQQMTRSQRKKLSTKVAFEMIMRNQSYSNLVELLLPNHVRLSIHAHNNAGPKFGIQLFDPAVVRAVEGLSPDGTPMASRDLLHIPTPWHNCVAEVEGSPYLLVTKASIPREAMSLGAVTGEVATREAPCFVLRPREHGVAAVDKAGEKIESPPAAVADKLTPAPTTPTPAQKPNAPKSRGRFDWARRLAAFPVICWLGMVFYHRVVEAFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBP3</accession>
    <name>E3QBP3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_03526</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092402.1">
        <property type="nucleotide sequence ID" value="XM_008094211.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBP3"/>
    <dbReference type="STRING" id="645133.E3QBP3"/>
    <dbReference type="GeneID" id="24408891"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03526"/>
    <dbReference type="eggNOG" id="ENOG502T0TG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_199238_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ28382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="66" mass="7192" checksum="9EB46B461117F68D" modified="2011-01-11" version="1">MPVINSIIARDAVHQLAKRENWASKEAGVIVVFAIVFLVAVGVTGLCISRCLSRRKAKRLATESRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBR2</accession>
    <name>E3QBR2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP transcription factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_03545</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092421.1">
        <property type="nucleotide sequence ID" value="XM_008094230.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBR2"/>
    <dbReference type="GeneID" id="24408910"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03545"/>
    <dbReference type="eggNOG" id="ENOG502SU86">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020925_1_1_1"/>
    <dbReference type="OrthoDB" id="3535998at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021833">
        <property type="entry name" value="DUF3425"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012">
        <property type="entry name" value="B-ZIP TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012:SF2">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11905">
        <property type="entry name" value="DUF3425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ28401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="524" mass="57792" checksum="81BC4F5E76AD61EF" modified="2011-01-11" version="1">MAHTAVANTRTRSVTTTVVAQHDKYPVDNMTRSASAEPTKPTKRKGTRSVSTLTPSQLARKRANDREAQRAIRARTKEHIERLERELEELKSERGRDQSQTVQELLRKNKALEEELFKLRESMGVPNGQSYPNSGMAASSVASSSAWLPLVRADSAPVYDDNLSSISGAVPSPRSSPFPSNGDYNVMQELGPSYVPMPDASESWGPGIPVSVPSTVSSPSSSANTDEYGTGYIPTSVPAPMMDARSIPAKMDYDEVDSVVELVPNSSVLSTTVGSLIRRPGTILWEVPTLIVPPTCRIDQLIVGFIQDCRRLAQLKPLDNILRPTRVNVKNFLEYHPASPTSQPPRCQLADLDRAASTAITGPGVNHPIAELITALVNTAGVTNVIERLAVFAITQKAVAWLVHPTRDAYAAIVRELTPKPCQTSIPHPQWIDLVLWAPLRTALIERQEVYANEEFQSVYSASLRLINWPCRPIDALVVDPQSGEMWLSETFTSHAMRIENWRLDENFIRRYPELRGCVAVQGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBS2</accession>
    <name>E3QBS2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl hydrolase family 16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_03555</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092431.1">
        <property type="nucleotide sequence ID" value="XM_008094240.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBS2"/>
    <dbReference type="STRING" id="645133.E3QBS2"/>
    <dbReference type="GeneID" id="24408920"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03555"/>
    <dbReference type="eggNOG" id="ENOG502S1W9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019533_3_1_1"/>
    <dbReference type="OrthoDB" id="192832at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02182">
        <property type="entry name" value="GH16_Strep_laminarinase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF60">
        <property type="entry name" value="GRAM-NEGATIVE BACTERIA-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26113">
        <property type="entry name" value="GH16_XgeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180289" evidence="1">
        <location>
            <begin position="19"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="2">
        <location>
            <begin position="15"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ28411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="281" mass="30700" checksum="2F503D9C8EE03DAC" modified="2011-01-11" version="1">MISTTASLLLALLPVVTALVPPPADGMNIIWSETFQGNAGSPPRRDTWDVALAIDTNNEVQTYTESSWNVQISGGETIQLIPRRSASGVWTSARIETKAAWTPQPGGRMRVQSMFRMGENANKQGMWPAFWMLGDAVRHGVQWPLCGELDIFEQINGQLSATGTVHCQQEVGGICNEPAGRGVATSLPDNGWHTWALEWDRTSNNWATETITWMRDGVVFNQLRGSDIGDEGIWATLAHMPYYVLMNVAVGGTLPGPPTDATQDGYGSMMEIGYLAIYQSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBS9</accession>
    <name>E3QBS9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">DNA-directed RNA polymerase subunit beta</fullName>
            <ecNumber evidence="14">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">GLRG_03562</name>
    </gene>
    <organism evidence="24">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="25 26">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="14"/>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092438.1">
        <property type="nucleotide sequence ID" value="XM_008094247.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBS9"/>
    <dbReference type="STRING" id="645133.E3QBS9"/>
    <dbReference type="GeneID" id="24408927"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03562"/>
    <dbReference type="eggNOG" id="KOG0214">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000524_5_2_1"/>
    <dbReference type="OrthoDB" id="10248617at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005721">
        <property type="term" value="C:pericentric heterochromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003968">
        <property type="term" value="F:RNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140727">
        <property type="term" value="P:siRNA-mediated pericentric heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.270.10:FF:000006">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.150:FF:000002">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1110.10:FF:000003">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1800.10:FF:000002">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="entry name" value="DNA-directed RNA polymerase, subunit 2, domain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1800.10">
        <property type="entry name" value="RNA polymerase alpha subunit dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1110.10">
        <property type="entry name" value="RNA polymerase Rpb2, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037034">
        <property type="entry name" value="RNA_pol_Rpb2_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007646">
        <property type="entry name" value="RNA_pol_Rpb2_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007647">
        <property type="entry name" value="RNA_pol_Rpb2_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04566">
        <property type="entry name" value="RNA_pol_Rpb2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04567">
        <property type="entry name" value="RNA_pol_Rpb2_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 14" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 14" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 14" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RNA polymerase beta subunit protrusion" evidence="19">
        <location>
            <begin position="38"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="18">
        <location>
            <begin position="245"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="20">
        <location>
            <begin position="509"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="21">
        <location>
            <begin position="608"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="22">
        <location>
            <begin position="708"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase subunit 2 hybrid-binding" evidence="16">
        <location>
            <begin position="785"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="17">
        <location>
            <begin position="1159"/>
            <end position="1251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="144"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="949"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="166"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU363031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF04560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF04561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF04563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF04566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF04567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="EFQ28418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1259" mass="142124" checksum="78524E7C4AF68CA8" modified="2011-01-11" version="1">MADVYDEYDYDGYVDEDDTSITPEDCWTVISSFFESKGLVSQQVDSFDEFTSSTVQELIDEYSQITLDQPNPMSDSDKVIALRRYEVKFGTVMVSRPSITEADGKVTTLLPYECRDRNLTYASPLYVKITKKVSIAVEKPIPLNELDEEQQDELANTGEHPTKLEWEEEESGEDYGADKNKSDDMKDMIFIGRMPIMVKSKICHLSSEQEDDLFMLNECPYDQGGYFIINGSEKVLIAQERSAANIVQVFKKAQPSPYSYTAEIRSALEKGSRLISSMMLKLYSKGDAAKGGYGQTIHCSLPYVKADLPIAIVFRALGVVSDEDILNHICYDRNDSQMLEMLRPCIEEAFCIQDREVALDFIGKRGSNHNIPREKRVRTAKDILQKETLPHISQSEGSETRKAFFLGYMVHKLLQCALGRRDTDDRDHFGKKRLDLAGPLLAKLFRNIVRRMNQELSGHLKRCVESNRQFSLTLGVKPQTLSNGLKYSLATGNWGDQKKAMSSTAGVSQVLNRYTFASTLSHLRRTNTPIGRDGKLAKPRQLHNTHWGLVCPAETPEGQACGLVKNLSLMCYVSVGTPAEPIIDYMIQRGMEVLEEYEPLRYPNATKVFLNGVWVGVHQDPRILVPDVQGTRRRNVISHEVSLVRDIRDREFKIFSDAGRVMRPVFVVEQSANGIVPQGSLVLQKATVNEMREQQENPPDNPADKITWESLAHSGVIEYLDAEEEETAMICMTPEDLEIYRLQKQGQVVEDNADGPNSRLKTKINPTTHMYTHCEIHPSMLLGICASIIPFPDHNQSPRNTYQSAMGKQAMGFFLTNYSRRMDTMANILYYPQKPLATTRSMEFLKFRELPAGQNAIVAIACYSGYNQEDSVIMNQSSIDRGLFRSLFFRSYTDCEKRVGINLVEQFEKPFRSDTLRLKHGTYDKLDDDGIVAPGVRVSGEDIIIGKTSPISPDNAELGQRTTQHVKRDASTPLRSTENGIVDQVIVTTNQDGLRYVKVRVRTTKIPQIGDKFASRHGQKGTIGVTYRQEDMPFTAEGITPDIIINPHAIPSRMTIAHLIECLLSKVSTLKGMEGDATPFTDVTVDSVSQLLRDQGYQSRGFEIMYNGHTGRKLRAQVFFGPTYYQRLRHMVDDKIHARARGPVQIMTRQPVEGRARDGGLRFGEMERDCMIAHGAASFLKERLFEVSDAFRVHVCEICGLMTPIANLSKQSFECRPCKNKTKIAQIHIPYAAKLLFQELQSMNIAARMFTNRSGVSIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBU4</accession>
    <name>E3QBU4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cell surface protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_03323</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092199.1">
        <property type="nucleotide sequence ID" value="XM_008094008.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBU4"/>
    <dbReference type="STRING" id="645133.E3QBU4"/>
    <dbReference type="GeneID" id="24408688"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03323"/>
    <dbReference type="eggNOG" id="ENOG502SM0P">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047729_4_0_1"/>
    <dbReference type="OrthoDB" id="5310497at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021476">
        <property type="entry name" value="Egh16-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34618:SF1">
        <property type="entry name" value="SECRETED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34618">
        <property type="entry name" value="SURFACE PROTEIN MAS1, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11327">
        <property type="entry name" value="Egh16-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180292" description="Cell surface protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ28179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="287" mass="29149" checksum="73F4E229374E4807" modified="2011-01-11" version="1">MKYSSTILFAAFAATNVLAHGVIDSVQGANGVNLPGLSLIDGTPRDCASPRCGSEADTSIIRDRELGTNRASALGRTQGGGPVDAAAMIQNFMDGAAGNTTAAKEARAVHEEMMARRNIAARQNGGGSKTPKGTVETGVKAATGMAASGGLPTTADDGTLKMTFHQVNQDGAGPLLADVDATSGGTDPSAFKKAEVTQNVPGIGFGGLSGASTMDFPVAIKMPAGMTCQANVGGASNVCVARLRNAALAGPFGGSVAFTQSATARKRAIEFNLRKRTETREARAFKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBV6</accession>
    <name>E3QBV6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NAD dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_03335</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092211.1">
        <property type="nucleotide sequence ID" value="XM_008094020.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBV6"/>
    <dbReference type="SMR" id="E3QBV6"/>
    <dbReference type="STRING" id="645133.E3QBV6"/>
    <dbReference type="GeneID" id="24408700"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03335"/>
    <dbReference type="eggNOG" id="KOG1502">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_9_2_1"/>
    <dbReference type="OrthoDB" id="2735536at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050425">
        <property type="entry name" value="NAD(P)_dehydrat-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366:SF562">
        <property type="entry name" value="ALDEHYDE REDUCTASE II (AFU_ORTHOLOGUE AFUA_1G11360)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366">
        <property type="entry name" value="NAD DEPENDENT EPIMERASE/DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="3">
        <location>
            <begin position="15"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ28191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="357" mass="39277" checksum="F641C8EA372593B1" modified="2011-01-11" version="1">MASLTNPAIPRGSLVLVTGVNGYLGSHVADQFLHYGYNVRGTVRDVASNGWLCDLFEGKYGKGRFELVAVPDMNTEGAYNEVVKGTSAFIHVAAVVGFTPNPHEVIPITVAGSLNALKAAYAEPGVKRFVLTSSSSAVVPADPVTYKQQPHVITHDTWSADAVELAYAPPPYTPDRSIIVYSASKVESEKAVWEYHKEHRHARPDLVVNAVLPNTNFGKCLDVANQGYRTSARFILCLWKGVAIPEAARTPYYFVDVQDTGVLHVAAAVLPEVQDERIFAFAEPFNWDRVLAILRQQNPDHSFGDDFEGTEFPHTIEPRDRAETLLKKMGRPGWTSLEDSLLNNTESLRKVETSPVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>E3QC19</accession>
    <name>E3QC19_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">NEDD8-conjugating enzyme UBC12</fullName>
            <ecNumber evidence="11">2.3.2.34</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">E2 ubiquitin-conjugating enzyme 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">NEDD8-conjugating enzyme Ubc12</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">RUB1-conjugating enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">Ubiquitin carrier protein 12</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Ubiquitin carrier protein UBC2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Ubiquitin-conjugating enzyme E2 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Ubiquitin-protein ligase UBC2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">GLRG_03398</name>
    </gene>
    <organism evidence="21">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine + [E2 NEDD8-conjugating enzyme]-L-cysteine = [E1 NEDD8-activating enzyme]-L-cysteine + [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine.</text>
            <dbReference type="EC" id="2.3.2.34"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein neddylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="17">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.34" evidence="11"/>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092274.1">
        <property type="nucleotide sequence ID" value="XM_008094083.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QC19"/>
    <dbReference type="STRING" id="645133.E3QC19"/>
    <dbReference type="GeneID" id="24408763"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03398"/>
    <dbReference type="eggNOG" id="KOG0420">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030988_6_0_1"/>
    <dbReference type="OrthoDB" id="10249039at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061654">
        <property type="term" value="F:NEDD8 conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23794">
        <property type="entry name" value="UBCc_UBE2F_UBE2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000005">
        <property type="entry name" value="NEDD8-conjugating enzyme Ubc12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 17" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="19">
        <location>
            <begin position="29"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="16">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00039884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00041569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00042179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00042190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00043698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00044279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00044315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EFQ28254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="183" mass="20806" checksum="83C3BD8F9C91596E" modified="2011-01-11" version="1">MLKIWSMKKEQQKAENADAAGGKKKKVTAAQLRVQKDLSELSLGSTMKTDFPDPDDILHFTLTIEPDEGMYRTGRFTFTFDINQNFPHEPPKVRCKEKIYHPNIDLEGKVCLNILREDWKPVLNLNAVIVGLQFLFLEPNASDPLNKEAAEDLRLNREGFKRNVRTAMGGGSVKGQSYDRVLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCA0</accession>
    <name>E3QCA0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">40S ribosomal protein S3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_03632</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the universal ribosomal protein uS3 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092508.1">
        <property type="nucleotide sequence ID" value="XM_008094317.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCA0"/>
    <dbReference type="STRING" id="645133.E3QCA0"/>
    <dbReference type="GeneID" id="24408997"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03632"/>
    <dbReference type="eggNOG" id="KOG3181">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058591_2_0_1"/>
    <dbReference type="OrthoDB" id="10248446at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003906">
        <property type="term" value="F:DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990145">
        <property type="term" value="P:maintenance of translational fidelity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070651">
        <property type="term" value="P:nonfunctional rRNA decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000056">
        <property type="term" value="P:ribosomal small subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd02413">
        <property type="entry name" value="KH-II_40S_S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1140.32:FF:000004">
        <property type="entry name" value="40S ribosomal protein S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.20:FF:000006">
        <property type="entry name" value="40S ribosomal protein S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.32">
        <property type="entry name" value="Ribosomal protein S3, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036419">
        <property type="entry name" value="Ribosomal_S3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057258">
        <property type="entry name" value="Ribosomal_uS3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001351">
        <property type="entry name" value="Ribosomal_uS3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018280">
        <property type="entry name" value="Ribosomal_uS3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005703">
        <property type="entry name" value="Ribosomal_uS3_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003219">
        <property type="entry name" value="PRK04191.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01008">
        <property type="entry name" value="uS3_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11760">
        <property type="entry name" value="30S/40S RIBOSOMAL PROTEIN S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11760:SF32">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00189">
        <property type="entry name" value="Ribosomal_S3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="Prokaryotic type KH domain (KH-domain type II)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54821">
        <property type="entry name" value="Ribosomal protein S3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00548">
        <property type="entry name" value="RIBOSOMAL_S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 7 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="KH type-2" evidence="9">
        <location>
            <begin position="24"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="222"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="234"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ28488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="261" mass="28531" checksum="0F2911BAE5639121" modified="2011-01-11" version="1">MAVPGTQISKRRKFVADGVFYAELNEFFQRELAEEGYSGVEVRVTPTVTDIIIRATHTQEVLGEQGRRIRELTSLIQKRFKFPENSVSLYAAKVQNRGLSAVAQCESLRYKLLNGLAVRRACYGVLRFIMESGAKGCEVVVSGKLRAARAKSMKFTDGFMIHSGQPAKDFIDSATRHVLLRQGVLGIKVKIMRGSDPEGKAGPQKTLPDAVSVLEPKEEQAVVQPMSQDYGAKAAQAQAAAEAQQAEQQAQEGGEEAEAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCD2</accession>
    <name>E3QCD2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Peroxin 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_03664</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092540.1">
        <property type="nucleotide sequence ID" value="XM_008094349.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCD2"/>
    <dbReference type="STRING" id="645133.E3QCD2"/>
    <dbReference type="GeneID" id="24409029"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03664"/>
    <dbReference type="eggNOG" id="ENOG502S1QP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016177_0_0_1"/>
    <dbReference type="OrthoDB" id="2357318at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055334">
        <property type="entry name" value="PEX8-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39214">
        <property type="entry name" value="MICROBODY (PEROXISOME) BIOGENESIS PROTEIN PEROXIN 8 (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39214:SF1">
        <property type="entry name" value="MICROBODY (PEROXISOME) BIOGENESIS PROTEIN PEROXIN 8 (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26001">
        <property type="entry name" value="Pex8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ28520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="687" mass="75714" checksum="E5959D739EC76F80" modified="2011-01-11" version="1">MPADRLLNTVLQLYQNVHDDRKTDQIIGSTVNLLANLSNPLNLGVLTSQLLIAPAIWHRREGLQTSLRIISIYNSAAIRVRQNGLDNAKIKIPNAPRQGGGLSCDTWVRAVVKGADERSNRWQHLLVLTGILMGMEGNDRKSLSRGLRNTLEEAVVTAANLALESQDGSFASASIVLALNYVFPFLSDLHQSAINCNALLPIAVLAITGEDGFQDGRFLEDIRKDVRQHGQMVEWAPNTSSFQLLQSIERKPLMGGMGPLSRLTAFAVTNATDSAIVLEAQDCLLEFSQKLFQQWQRNPLSTVDAADETARLEPNTLEATWPVLWGTLKKTMYATVAVMQAVIGRSLLDPRMRNDVTAPQVATKSLHTLRFLFFISSRHGAGAFQAYTFTYLTSLDILARFGDACVSFLGETKPPHAGAVPPSPLDRTLDLFYMNVSEHLPLNMPTEACDSLIVRPATAYLTHIGTMTATMVELFEAAHSAVLSVLSCPHNGPLTVSLVPFYIDALFASFPSQISSRQFRVAFKTVMQIVSPPFPISLMEPQLSETLLEMVRFKAMDASTTLLPQTQDVIAQSEKGLTTQQEPLSEQSSLVLTLIDSLPFLPLPLVEDWMTLTAQAMNEISDPVMRQPVKDRFWEVLVSGEMDVERATIGVAWWTTKGGRELVLGRVVQQVPMMSGAIMDESKSSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCP0</accession>
    <name>E3QCP0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_03772</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092648.1">
        <property type="nucleotide sequence ID" value="XM_008094457.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCP0"/>
    <dbReference type="STRING" id="645133.E3QCP0"/>
    <dbReference type="GeneID" id="24409137"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03772"/>
    <dbReference type="eggNOG" id="ENOG502SUXP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114624_0_0_1"/>
    <dbReference type="OrthoDB" id="4848615at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ28628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="165" mass="18775" checksum="C5179C0B8F494C25" modified="2011-01-11" version="1">MSEHYNDPIAKRILVSVSKKSPHWSLAWLEDERLVDEQLVNVAIVLLNSSNKAAQVAHTDTMLVAAERWPMRIWIVIDIFNTKYDPSKAHLPGQNDLPVIVISFSKKSSIQIATEGIKNMVNRRIQEVHDLHGDESRAPLRIDHANNNIPTFPSPRTRIPMMPDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3QD03</accession>
    <name>E3QD03_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_03919</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092795.1">
        <property type="nucleotide sequence ID" value="XM_008094604.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QD03"/>
    <dbReference type="STRING" id="645133.E3QD03"/>
    <dbReference type="GeneID" id="24409284"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03919"/>
    <dbReference type="HOGENOM" id="CLU_2573741_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ28775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="81" mass="8270" checksum="ACD6C1267E294CF8" modified="2011-01-11" version="1">MADSQNNTAPDNGAAPANDPAPTSDPVIVANDDVTDDATSDAATSLASPTTSLASSIPKHRIENGRTYLKYKDGSEPSPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDH6</accession>
    <name>E3QDH6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_04092</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092968.1">
        <property type="nucleotide sequence ID" value="XM_008094777.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDH6"/>
    <dbReference type="STRING" id="645133.E3QDH6"/>
    <dbReference type="GeneID" id="24409457"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04092"/>
    <dbReference type="eggNOG" id="ENOG502SN6I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032417_0_0_1"/>
    <dbReference type="OrthoDB" id="1919336at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052360">
        <property type="entry name" value="Transcr_Regulatory_Proteins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206">
        <property type="entry name" value="ASPERCRYPTIN BIOSYNTHESIS CLUSTER-SPECIFIC TRANSCRIPTION REGULATOR ATNN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206:SF4">
        <property type="entry name" value="HYPOTHETICAL CONSERVED PROTEIN (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="69"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ28948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="622" mass="70638" checksum="8142B01EAFF196CA" modified="2011-01-11" version="1">MNGASYFSDTLEEPEAANSALGRLHSRVLPLLPRLASTLPSNQVTGLVKRGPGDAPRRKRASKPKVRSGCLTCKIRRVKCDERKPTCSRCEKADIDCDGYIKEAMDQKKTTEQQQIVAAAQQASRYLLPRPNVPGKQGSVPILTARLRTNPSLLHFDHKDVPYYDLFRYQLIRDLGGSCQADFWSRIVLNEMTRDPVPPSALRPWGTSKAVLTGFLNRHHKAALLHHVKAVAIYRERIQQSASDTSPRSIIIMTLLLIAFEFIQGNMKNIDSLMGTGMRLLENKITLLHGLQPGEEFEVRGDYIYSRLRTGTPDDEMEDIEHLLPCLCLMAGFTHFFSSHRNSVLLMNSSPKLQLPKPGVTVLAKLQALWGQFFTRAVVHVMRTVHDQLNYNPMDILKAAEEQERFVEYIGMWQGVLETYLSDPTLDEDARRTLDSIQIHRLLIHIVISCSLDRSEMMYDLFELEFRELLDRVVCYLRDPGPISKVCFTFSEGLTSPLAMIIAKCRNHNIRMEGINVLNSLSWRENAWDGQALVVGKSGVVWLEDKGMDENGFIPPDSRWIWMSSKWDIEKRELLATYFRLTPNDDGTPFCAQLTLDMDNLVYSCDSIGCPGRHDPFKINQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDL2</accession>
    <name>E3QDL2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04094</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ28950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092970.1">
        <property type="nucleotide sequence ID" value="XM_008094779.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDL2"/>
    <dbReference type="GeneID" id="24409459"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04094"/>
    <dbReference type="HOGENOM" id="CLU_1094190_0_0_1"/>
    <dbReference type="OrthoDB" id="4857371at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ28950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="254" mass="28206" checksum="0B104449FEBF9FA5" modified="2011-01-11" version="1">MMRDPNAYSDVESDDTNDGEVDDNKGEEESPSGKRVAKRRKTTIRTFKENFTRTPKTFNPENRVERQIPCVPCLSAALHGNSDGRCFKGNGNRCLRCFGGRSKEKCVPIAPTLRVFARQHIEIMSRRHRASEIGRLRSAIRLVRDYTEDIEHEVISAHIATTPAEPEVQQALQLSTLQGSTVVANIAPVEGSAPAVVVKEVIDPIFVKKEAASNLVAVVDNYNERKAKFLDAIEPLVDGPLVGAIGRYLDKHMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDP5</accession>
    <name>E3QDP5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_04127</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ28983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093003.1">
        <property type="nucleotide sequence ID" value="XM_008094812.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDP5"/>
    <dbReference type="GeneID" id="24409492"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04127"/>
    <dbReference type="eggNOG" id="KOG4831">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108086_3_0_1"/>
    <dbReference type="OrthoDB" id="43458at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018908">
        <property type="entry name" value="TMEM234"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28668">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28668:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10639">
        <property type="entry name" value="TMEM234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ28983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="141" mass="15833" checksum="BCC76E2C4B7275AD" modified="2011-01-11" version="1">MTSPDGPEHQPAAINYVAGFLLVGLAWGFTTPFIRRAAKDHHPPPHPVLETDAVKRSWFRGRVYGAFFGVVDLLRNPRYAVPLLINLTGSVWFFLLIGQAELSLTVPIVNTLAFLFTVIGDWWVESKVISRGRPQFLSEFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QE60</accession>
    <name>E3QE60_COLGM</name>
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        <submittedName>
            <fullName evidence="3">BRCA1 C Terminus domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_04292</name>
    </gene>
    <organism evidence="4">
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        <name type="common">Maize anthracnose fungus</name>
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        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
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        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093168.1">
        <property type="nucleotide sequence ID" value="XM_008094977.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QE60"/>
    <dbReference type="STRING" id="645133.E3QE60"/>
    <dbReference type="GeneID" id="24409657"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04292"/>
    <dbReference type="eggNOG" id="ENOG502SKU0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054245_0_0_1"/>
    <dbReference type="OrthoDB" id="427711at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="150"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="131"/>
        </location>
    </feature>
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        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ29148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="244" mass="25751" checksum="6ED8B03FFC28D474" modified="2011-01-11" version="1">MPSTEKPSVPPAAKPRFGSTFDPYNSSSTGHQRPENTPGATTGWRTSRVRKLSEQFAGGHSGGARMSDTYGAGSEDFDEKLKMVVPKDVKARAKMSVADMLARPGLMRGGSSVSETGSATSATGGNSTSEEGILEAHRKEDEEKEPKKAAGRGLFEGVTVYINGSTHPIISDHRLKRVLVENGGRMSIHLGRRQVTHVIVGRPASVGAGAGGGLAGSKLDREIRKVGGCAVKYVSVEWQGFGES</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEP5</accession>
    <name>E3QEP5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7727 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_04495</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
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    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008095180.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEP5"/>
    <dbReference type="GeneID" id="24409860"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04495"/>
    <dbReference type="eggNOG" id="ENOG502S16N">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_132815_0_0_1"/>
    <dbReference type="OrthoDB" id="2110422at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056144">
        <property type="entry name" value="DUF7727"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40629">
        <property type="entry name" value="PRO41 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40629:SF1">
        <property type="entry name" value="PRO41 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24853">
        <property type="entry name" value="DUF7727"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7727" evidence="2">
        <location>
            <begin position="1"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ29351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="144" mass="16143" checksum="EC2E2EA37E6107D8" modified="2011-01-11" version="1">MGRLIKNHWARLIVISAAVYQLAAAVEGFFYPKIFWDFLTKSLDPAVKPVPVLQIINLIMALFMVALEWPLVFLAGSAVHRSLEFRLIILPLTSLASALIYQGTNSAIYYVVGLIVYFWAYSEGEIICAKPWTLPQRGRSGGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEU7</accession>
    <name>E3QEU7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Rad17 cell cycle checkpoint protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_04547</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the rad17/RAD24 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093423.1">
        <property type="nucleotide sequence ID" value="XM_008095232.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEU7"/>
    <dbReference type="STRING" id="645133.E3QEU7"/>
    <dbReference type="GeneID" id="24409912"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04547"/>
    <dbReference type="eggNOG" id="KOG1970">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006397_1_0_1"/>
    <dbReference type="OrthoDB" id="10265971at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003689">
        <property type="term" value="F:DNA clamp loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000077">
        <property type="term" value="P:DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004582">
        <property type="entry name" value="Checkpoint_prot_Rad17_Rad24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057927">
        <property type="entry name" value="RAD24-like_helical"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12172">
        <property type="entry name" value="CELL CYCLE CHECKPOINT PROTEIN RAD17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12172:SF0">
        <property type="entry name" value="CELL CYCLE CHECKPOINT PROTEIN RAD17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03215">
        <property type="entry name" value="Rad17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25812">
        <property type="entry name" value="RAD24_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Checkpoint protein RAD24-like helical bundle" evidence="9">
        <location>
            <begin position="516"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="537"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="713"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="807"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="23"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="115"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="171"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="813"/>
            <end position="824"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF25812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ29403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="877" mass="95417" checksum="0C77444FE85EBD6F" modified="2011-01-11" version="1">MAPPAKRRRRNVVESDDEDDQQPKTNTLTNFLLSSPAKSDSRGASVSPSPTKPKPRVAYNTRAVATPAVLQSRNGQSNKGTKSPSTSPEKFKGKQQKRVKVDDKGRNGDLMTLFSKQASKASARPAAASRTVPLDDIVSDPISEEDDVAEQKASTSSIVGQNARKRFRDSTPISSSATAGSSQKFLKPPRPMKPAGLDDDDDDLRPWSERFGPLNLEELAVHKRKVADVRKWLEDVVGGRLRQRLLLLKGAAGSGKTTAMRLLAKDMGYELLEWRNPTNTLGAHLGYTSASAQFQEFLSRGGKFGQLDTDVPTEAPRPANEKSASAGKIILIEEFPNTFSRSSTALSSFRSTLLEYLAANTPSLTTFGRRSPSEPITPVVLIVSETLLTTTSASADSFTAHRLLGPEILRHPGTRVIEFNTIAPTLLAKALELVVLKEARKSGRKRTPGPQVLKRLGEIGDIRSAISSLEFMCLKGDQDADWGAKVALSKQSKGAKAGISLTKGEKETLELISQREASLGIFHAVGKVVYNKRDETPSASNAAERLPSYIAHHSRPKPSEVSVDALMDETGTDTQTFVSALHENYMFSCETVPPFDASTPLDYVNGCIEYLSESDLLLPCRDSFFGGRGSSASFGRDSGSHVLRQDEIAFQVAVRGMLFSLPSPVKRKASTGAKGADAFKMFYPTSIKLWRTKEEFEALVDVWSTKLMKGEETASRRSLTEGASAFRRPKQTDAGNWVANRQSKPKPANENAKADSNVAPLLSLGSAARREMLLERLPYMASIVRGRKSTLHSFKLREIEKVVSFQGIGPQTGDDDEPAEDAPEDGVMTGDAWATDKPSEEASPRKWSSVIRHAGDGSVAGLRVQNLVISDDDIEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFP6</accession>
    <name>E3QFP6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA repair protein rhp7 treble clef domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_04875</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093751.1">
        <property type="nucleotide sequence ID" value="XM_008095560.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFP6"/>
    <dbReference type="STRING" id="645133.E3QFP6"/>
    <dbReference type="GeneID" id="24410240"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04875"/>
    <dbReference type="eggNOG" id="KOG1947">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006598_1_0_1"/>
    <dbReference type="OrthoDB" id="1924287at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000601">
        <property type="entry name" value="DNA repair protein Rad7, protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056451">
        <property type="entry name" value="Znf_Tbcl_Rhp7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318:SF234">
        <property type="entry name" value="RNI-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23550">
        <property type="entry name" value="zf_Tbcl_Rhp7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA repair protein rhp7 treble clef" evidence="2">
        <location>
            <begin position="176"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ29731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="650" mass="72243" checksum="64FEA76848C42B64" modified="2011-01-11" version="1">MVRPTRQRAQAQAQGQNQNQAQPAQQTQDSQQDQAAPQTQAQGANRPARHISGPQSALTDYLASHNISANQIRRNADQRRAAAARSLEAQGGNNAEDGEEAAGPSTEPTETTESARNETSAERDKRKRKEQQALAKIKASKSFKKRKRHAEHFTGVSEDDDDFARTIFNQREKPMPGQMDNCAICKKRFTVTAYSLTGPEGGLLCAQCSKDHAAKKGKGAKKPRKSLGGQGSRRKVQSNILDGTYQTGAKDLTTLCIETLAKNVDLADSLGDLPDKVVDKIARLFSKRRLLTPETLPLFVQPSTLTVKIYDGAKLGPNDFEGIFQTASGLQHFKARNAIQFKDEVMDYLLTRDTKILSFNIHGANLLSDSSWSMFISTKGADLEAIQVYYTDRHFGDEILNQLSINCPKLNRLKVYHNQKVTNIGVRAIGDIKTLKHLGLHLQHDISPKSLSHMICGAGQLLETLSLRKMPKSNDEVLTAIKNTCRSLRKLRITDSEDMTDEGFVDLFTDWENPAIDVIDFQKCRHLESTNPRNNPDGVGLCSDGFRALMKHSGGKLKNLNIHACRHIRRDAFEDVFSKDDQYPHLVKLEISFIEDVDDFVLGRIFRSCPNVREINVFGCMKVKDVKVPKGKVLVGVPNAIGMVIEGQDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QH30</accession>
    <name>E3QH30_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GEgh16 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05336</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697348">
        <property type="protein sequence ID" value="EFQ30192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094212.1">
        <property type="nucleotide sequence ID" value="XM_008096021.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QH30"/>
    <dbReference type="STRING" id="645133.E3QH30"/>
    <dbReference type="GeneID" id="24410701"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05336"/>
    <dbReference type="eggNOG" id="ENOG502SJ8E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047729_1_1_1"/>
    <dbReference type="OrthoDB" id="3241054at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021476">
        <property type="entry name" value="Egh16-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34618:SF3">
        <property type="entry name" value="GEGH 16 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34618">
        <property type="entry name" value="SURFACE PROTEIN MAS1, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11327">
        <property type="entry name" value="Egh16-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="346"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="388" mass="39095" checksum="D5567BF813A4DC3B" modified="2011-01-11" version="1">MLSFKDIFIASAVAAVAHGHGVILNAQGDAGSPASVGFKVDPNIARNCTTINPCQQDATLIRDAEINANIVNECGRTEISGNIDIGENTENALSAGQVTKVKAGSELTVTIHQVNADGAGPYACDLDPTSNSLGGSGQIPLQVTNNVPGVNGFSQAKAQQFNITVKLPNDLKCTGASTGDICTVRCRNNAVAGPFGGCFPIQQTDVTPTANTPQNIKTLKDLNTILKQQQGNTKDLPAAIKANQIDGTAEQKAAADAAVKLLGTPDVVIKDSPATDTGPSTGSGNGNGNGNGNGNANGNGNANGNGNANGNGNTNGNGNTRGNGSTGKGAGKGAGNAAPAPPPAPNNNGGNRGGNRSNGNQKRGEGLLRWARRYVVVNDEADAVEVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>E3QH56</accession>
    <name>E3QH56_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="13">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_05362</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697348">
        <property type="protein sequence ID" value="EFQ30218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094238.1">
        <property type="nucleotide sequence ID" value="XM_008096047.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QH56"/>
    <dbReference type="GeneID" id="24410727"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05362"/>
    <dbReference type="eggNOG" id="KOG0054">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_27_6_1"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18596">
        <property type="entry name" value="ABC_6TM_VMR1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18604">
        <property type="entry name" value="ABC_6TM_VMR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001577">
        <property type="entry name" value="ABC bile acid transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001751">
        <property type="entry name" value="ABC bile acid transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000013">
        <property type="entry name" value="ABC transporter C family member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF415">
        <property type="entry name" value="FI20190P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="141"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="345"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="958"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1020"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1102"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="312"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="684"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="1010"/>
            <end position="1258"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1293"/>
            <end position="1510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="397"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="403"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ30218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1510" mass="168198" checksum="CAB37386967D2659" modified="2011-01-11" version="1">MMGSFATFEADGPPSGRLAFYSYAALQHVLSGPHLPHFSHTKFENATLTTTAHLGALNVMRVTDIVRASIAALLACLVLARPLLRKRPAWCRGFAQESLYSAAAHPPLKKSWTFWTIYLFAVALAGLVQASLSLLVPPHRVFSVLELVPSLVAVLITAADRPTKTPKTLLFLYFTILACGVVSTAFSYRLYRSIPMLVLADLIVALVGIIGILAMPMRDPSLGDDDVARKEPTDELRSPEDNLSLWRFMTVSWMAPMIARGYEKQLHNQDVWQLPFDFQHERLHALFHELRGSMTAKLFLANGLDLIIQSSLGTIECFAALSVPMLLQQLLRAIQSGPSNIEVSVLYAIAILAVRLLACQAAVFQLWFSRRCYERSRGEMITTIYAKTLSRKHFGQPAGEKMIDDDDGDDDYGDHGDEETDTDDVSADTGGQTGRFSRLLGWFRCGHSARPRYQRLQKPKAQRQPATTGKILNLMRNDVYEIAQRFWEFPTIVTKPLQFIFSFVLVWQLLGYSCLFGMACVVLAQMLNTIFITQLLKNERVRRAATDARLQSTSQFVEGIRHLRWYDWQSKWLDSIMATRRHELRTRVVTGLWSIAISTLNITSGTLFPVATFFAYTSIAGRTLTVDVAFPALSLFTLLETSFKELPGLITVLLNASIAMGRIEDFMSEPDKESIFSDHLTNDIKFTKATFAWPGYEQPVLKNLDISFPQGLTVVFGKVGSGKTALLQAILGELDRHAGEVIIPTEPIGYCAQSPWLQHMSIRDNVLFSAPFDPTRYTQTLDACALLPDLANFKHGDLSDMGENGIGLSGGQRARVALARAVYSQSRVLLLDDPLAALDHNTAESIVKKLLQGPLVEGRTVVLVTHRVDLCIHLASQMVEIVGNTARVLNSQEAAAEVAKFLSQDDDTAVRHEEPEQTLEEQQDAAVPSKFVEEEHRAHGGVMMSVYWCYIKAGKLKWWALLLLVFGLFRLGSLLNYWFLKAWGEAYKHETSTKGTSDGIGFSRLFDRLPDPNTDLGPWLWVYFAIAVAQALIYTLSEGLTLLMIITAARDLFKRVITKVSKATFRFYDVTPVGRLMNRLVSDIGMIDGGIMRPLREVAIQSITWFSSMVVIASVTPLFLVFSVGMTVWFVYVFMRFLPTSQSLRRLEMVSLSPLMSNFGILLDGLATIRAFKAQHHFQNMNIVVTDAFQKMDHFYWSLQAWLMYRFDALSAISTFCLTIVALHKGLSPGLTAFVLTTASAFVEATHNLCKQYGTLQMDFVSVERVIELLDIPEEPCGDITPPTSWPHHSDDVTFENVTLKYAPHLDPSVSEASFTIPGGSTCAVLGRTGSGKSTLALALLATIHPSEGAIRIGNYKLSSVDVHVWRQRVSFVAQDPVLFPGALRDNLDPLHQYTDTECIVVLHRVLGPGWDLYSRVEGGGKNLSQGQRQLIGIGRAVLRRSPIVVLDEATASIDKETAARVQEVLRNELTTSTVITIAHRLEAVQDANYFIRLDKGRVVEHGPTQGLNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHH6</accession>
    <name>E3QHH6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_05291</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697348">
        <property type="protein sequence ID" value="EFQ30147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094167.1">
        <property type="nucleotide sequence ID" value="XM_008095976.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHH6"/>
    <dbReference type="GeneID" id="24410656"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05291"/>
    <dbReference type="eggNOG" id="ENOG502R729">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_783051_0_0_1"/>
    <dbReference type="OrthoDB" id="5233297at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="266"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="324"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ30147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="354" mass="38115" checksum="067CD24F2A8D71AC" modified="2011-01-11" version="1">MAKSPHPSPYTPISSPTAHEPPDGRARSSATKWDPGPDSTTFALVPAASYNTLVQLRPLTSRLLRGRRRLRRLLLPAEPGSDVLHALLARPAELSDGSPHLARAFAVVVFAILTNHVRRMVLPALGVGGFGAPITALKLAAGSPAIFLKEEMETGILGRSAGWEGASKVIGDIVGGFAVRGAVAGTPRRWDSEADKAMVVTAVVYCVWVLGCAEYVHARAVHTVAVSIAYAKLIRGGPTYRQALREILLPSTSSGVLKVLGSHLELAYYVTYGLLPLLCLAARSAFRPEPRRGGPGLALLVTGWAWGTGYVTRYSNKYYIGLEMSGLLLVVWWVLAAAAVFVWRALRTRFKVYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHX2</accession>
    <name>E3QHX2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7371 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_05604</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697349">
        <property type="protein sequence ID" value="EFQ30460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094480.1">
        <property type="nucleotide sequence ID" value="XM_008096289.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHX2"/>
    <dbReference type="GeneID" id="24410969"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05604"/>
    <dbReference type="eggNOG" id="ENOG502RY34">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_297896_0_0_1"/>
    <dbReference type="OrthoDB" id="5385013at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055795">
        <property type="entry name" value="DUF7371"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24086">
        <property type="entry name" value="DUF7371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180460" description="DUF7371 domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7371" evidence="3">
        <location>
            <begin position="786"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="472"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="472"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="483"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ30460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1010" mass="100824" checksum="7FC73B6D03D8D32D" modified="2011-01-11" version="1">MRASIVAMSALAAGVFAQPTCPAATTVFVTVDSANDVAPSVVVQTVTATVLPSAHSPWSPASPSIPATFTIIVDPPTGGSQYTGPKPWESSPTQPPAFTVVTATLSSPDLGTSVGVSPASTTSCPFATVSPGSGSDTAGVTVITTTLHRTNAYPGQVTPSVDTVVATFTVTFPQPTATGSFPGSALTTGAADPGSGELFTYTITAPAAAGPSSGPGDDLAVTSFTTTLYRTRPGSVSGTPVVDALVTCFTVTFPSPTGTGPAITGIPAVSTDVPGGSPGGVVPGGSVGTTTRYIPTMVPGPDGSLSYSIQTVVSTFTSPSANLPSTAGTGVTTTIVPAYPSDTPSGEAATVVTTTLYAPLPSVNNQPADPSDPSVVVFTLTLPQPSAAGPVIYTTQLPSNPGNIATGGASTPAASTITVIRPAPSPGFPTPVPGSDMATSIPGGYGDPVLPGASGILTSGAPVSGIPASGGSVPGSVFPSGQIPGSPSAGSGNSQDTPGAPVTVTISPGGVGATPSSNFPGGYGDPAQTELPPFIPGSAVTLTVSQATPVAGGPTSVTVVPTSLVGVPTSVVGVPTSLLGGYDSVVVVDPGTLASLPQASPSVVTLWPVVPGIDSALPGAATTTSCSSTLSSEIVSTALLTSTLVNVVSDATTTYTFPYESLVTTVDAVAPTGAASTIVGSASVTGSAVVSTVVSAVTSVIVSPVTSAVVSPVISPITSAVISSVTSAVGLSTWQSVIVQSSVIQVFTTGVFTSLVQPTAIHKRYLNTTATAVTPVPTPICTGTTEVGNLNLDFDDVPSGPFFNPYHRFWFSKGFLVGPPPLMPFIPSSGGHLLEFVPPVLSNSSANGISGDTAQIGMGKLASSPCFQFDFLGMNLGCYSDSAVPNQLCVFTFTGYRWDASQAKETEAASQEAWVNACNKSSDCPLTSFSALGFTGLSSILVTLNISGRPQVWWADDLRVGWTKNDCVTASCRRQTQPEASQLHGGPTWFWTPSGLRILSSSRINPHLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QI10</accession>
    <name>E3QI10_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CRAL/TRIO domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_05642</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EFQ30498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094518.1">
        <property type="nucleotide sequence ID" value="XM_008096327.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QI10"/>
    <dbReference type="STRING" id="645133.E3QI10"/>
    <dbReference type="GeneID" id="24411007"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05642"/>
    <dbReference type="eggNOG" id="KOG1470">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016665_3_0_1"/>
    <dbReference type="OrthoDB" id="43460at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120010">
        <property type="term" value="P:intermembrane phospholipid transfer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052432">
        <property type="entry name" value="PITP/CRAL-TRIO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46590:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL TRANSFER PROTEIN CSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46590">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL TRANSFER PROTEIN CSR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03765">
        <property type="entry name" value="CRAL_TRIO_N"/>
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    </dbReference>
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        <property type="entry name" value="CRAL_TRIO_N"/>
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    </dbReference>
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        <property type="entry name" value="CRAL/TRIO domain"/>
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    </dbReference>
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        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
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    </dbReference>
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        <property type="entry name" value="CRAL_TRIO"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="205"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ30498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="469" mass="52688" checksum="C28DF38463986499" modified="2011-01-11" version="1">MATEMPPGRPGNLTPEQEEKLRQLWNLILSLGGDASTTAADSTSASIAPTETSTAGKDEKPKKKRVSLFSRKDKKEVGSTNSSATVHTTIKEDGEDKYGQTKQFQEALASQSPEALRAAIWAMVKHDHPDALALRFLRARKWDVEKAYVMMISTMNWRLTEMKVDEEIMRTGEAGALEASKSSDANTKKLGEDFMAQARSGKTFIHGLDKAGRPICQVRVRMHRQGEQCEESLEKYTVFLIETARMVLAPPVDTATIVFDMTGFSMANMDYTPVKFMIKCFEANYPESLGTVLVHRAPWVFQGIWKIIKGWLDPVVAAKVHFTNNVKEMSEFIEPSRILKELDGQEEWNYKYVEPIDGENDKMKDIATRDALVSGREDLIHEYEEATLQWIKEAGTDKEPAIKARRNELARKLRDDYWKLDPYIRAKCFLDRTGVIQEGGEINMYSKGAVASQATNGTPAVNTSADDVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIC6</accession>
    <name>E3QIC6_COLGM</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_05680</name>
    </gene>
    <organism evidence="2">
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        <lineage>
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            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EFQ30536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094556.1">
        <property type="nucleotide sequence ID" value="XM_008096365.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="24411045"/>
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    <dbReference type="eggNOG" id="KOG1516">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="6846267at2759"/>
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    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
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    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ30536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="184" mass="21287" checksum="F379A4161AF70F8B" modified="2011-01-11" version="1">MLYDFRKPGDSSSLYSRIFMDSNAIPAQPKSLAEVQGQFDELCDHFGIERSIPNSQKLGILRTKSVQDLLRTISHLKNHTFRPVTDDIFIHFGMVDYLQSRGFADEFKKREYKILIGEVLNEETLYASYNPPIEPTLDALRLQISNYYAPDVTDRAIKQYTLPNSSNLEDWQNIFGKTQEDVDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIG1</accession>
    <name>E3QIG1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_05715</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008096400.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIG1"/>
    <dbReference type="GeneID" id="24411080"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05715"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_22_1_1"/>
    <dbReference type="OrthoDB" id="10021397at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF199">
        <property type="entry name" value="MFS EFFLUX TRANSPORTER INPD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="75"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="199"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="227"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="272"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="302"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="340"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="381"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="405"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="435"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="468"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="534"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="76"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="570"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="31"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ30571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="603" mass="64630" checksum="A52AA4E8AC855492" modified="2011-01-11" version="1">MEPARKGSLEIVVRPEPNVDRASAENNNKNGVDHHLEEKTESSSRNPESNETSLQTGTGDESANHQYATPKELSLLSTVFTIATFMIAIDGSILATAIPKITSDFHQLDDVPWYGSAYLFTEMAFQPTFGRLYTLFDARVLYLISIILFEIGSILCAASPNSAVLITGRVISGTGAAGLLCGSLAVYGRSVPLRARPFGMALVTSMYGIAGVLGPTLGGLITDTPRLTWRFCFWINLPFGAVTFAIAYKILKAKTPVHGRLSLREKLKRLDLLGASMLLIGLVALFFALQWGGSRYPWSDPRVYACLIVSGIFLSAFVLLQATKKEEAIIPVRILSQRTVAISCVFNMLMSMAHNTHMYYLAFYFQAVLGTNAVTSGVRCLAYGIPCSIAIIVTGACISSRGHYVPFMWLGSGVFVAGCVLIQRLDRGSSIGEWLGFQVLSGAGIGLAEQVPFIAVQVVLPDDDMPTACALVVFHRLLGGAVGLSIASNLFSQELSRRLAGAPAGVNARAVRYAGASDLASAVPAADLPLVRGAFGYAVAKAFILPIAVAGISLLMSFGMQRRWIPDDRVQPAQGEEPTTTTTTTLDTPGAVSLDPVRCDRTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIX7</accession>
    <name>E3QIX7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">mRNA 3'-end-processing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">GLRG_05959</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 12">Component of the cleavage factor I (CF I) involved in pre-mRNA 3'-end processing.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the CPSF4/YTH1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094835.1">
        <property type="nucleotide sequence ID" value="XM_008096644.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIX7"/>
    <dbReference type="STRING" id="645133.E3QIX7"/>
    <dbReference type="GeneID" id="24411324"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05959"/>
    <dbReference type="eggNOG" id="KOG1040">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024513_1_1_1"/>
    <dbReference type="OrthoDB" id="1914176at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1000.10:FF:000012">
        <property type="entry name" value="cleavage and polyadenylation specificity factor subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045348">
        <property type="entry name" value="CPSF4/Yth1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23102:SF24">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23102">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14608">
        <property type="entry name" value="zf-CCCH_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18345">
        <property type="entry name" value="zf_CCCH_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 12" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="9 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0677">Repeat</keyword>
    <keyword evidence="8 12" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 11 12" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 11 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="14">
        <location>
            <begin position="38"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="14">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="14">
        <location>
            <begin position="100"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="14">
        <location>
            <begin position="129"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="14">
        <location>
            <begin position="158"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="11">
        <location>
            <begin position="38"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="11">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="11">
        <location>
            <begin position="100"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="11">
        <location>
            <begin position="129"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="11">
        <location>
            <begin position="158"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="185"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="214"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU369008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EFQ30815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="253" mass="28791" checksum="41BFEB32AE0C5D39" modified="2011-01-11" version="1">MAAVASRPETAQILNHAPTATSFSFTPFLRQTYRHELSSDRPQCKSFLAGHCPLGASCPDRHAYSTSSNPSGGPSLVCKHWLRGLCKKGESCEFLHEYNLRKMPECNFFMRNGYCSNGEECLYLHIDPQSKLPPCPHYDKGFCPLGPRCSKKHVRRKLCPFYLVGFCPEGPGCKYGAHPRWRTDLEKPSAKVEGEDEAKKDGEREDGEAFQQQQRERQRDMHDDRGHGDRRHGGRGGGKWRDRGNRRFRGRGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJ69</accession>
    <name>E3QJ69_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Ferric reductase like transmembrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_06051</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ferric reductase (FRE) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094927.1">
        <property type="nucleotide sequence ID" value="XM_008096736.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJ69"/>
    <dbReference type="STRING" id="645133.E3QJ69"/>
    <dbReference type="GeneID" id="24411416"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06051"/>
    <dbReference type="eggNOG" id="KOG0039">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010365_1_0_1"/>
    <dbReference type="OrthoDB" id="167398at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000293">
        <property type="term" value="F:ferric-chelate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015677">
        <property type="term" value="P:copper ion import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF9">
        <property type="entry name" value="FERRIC REDUCTASE TRANSMEMBRANE COMPONENT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="4 11 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180467" evidence="12">
        <location>
            <begin position="37"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="299"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="377"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="404"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="13">
        <location>
            <begin position="440"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ30907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="752" mass="85391" checksum="AA258439053DC43A" modified="2011-01-11" version="1">MRVLLSWSASAPRLAVHRILLSTLLAAMCLFRHSAAGILGPGDICFDSCSYALGAARFNDTRPYNGTDFQKAKLITSCESRLYITSMYLCADLHCDLMHRIAGLSDLNHTCQTSMNTSLPPFEIIANYSSEEIAGLRRLTKEEGVAKTVLNEIVLPADAFYQIWADTLDSVKYTYGYHFRYGFYVIVFWFIVIAIGLGSRLVSAIGDLQKREYDPRNTPGICHAPALWLKRYITVPATFGYRCSQNLGWCTIPPRVQSLTILAFIVVNIFFCIHGYKIFRGHMYWPTVYHLVWRYVADRTGIISFANFPIIWLFGMRNNLLMWVTGWDFGTYNNFHRWVARVATLQAVIHSVGYVVLVFDDGGLAYFVSYWKIMFWWAGWLATFGMVALVGASVYWMRRKQYELFLILHILLSILTLITMLGHVSIFNGEYDFLFWVPFYIWIGDRVLRMARTLAFNLRFWNTFALASYDTNSNIVRLSVPYPTSFYEPKPGTYYYLHVLSDKCFWESHPFTMARTTTNLSAGRKSSCEETPLLVAGEQDQEPVSEVALQPKRGEPSMTFLIRPYDSFTARLREKATAAWPHPARLRVLIEGPYGHTQPFDQFDGLLFIVGGSGVVVPLAHLAELTKDGSRARSVKIVWAVRELSFAADVLKQDFEDAFDSGKLSVDVYLTQHSPAASAARPDDWPEQVRLLHGRPEVREEVQEAAIGASKASLAVVACGPGVMADDARRSVVEMLDRGWSGVEYFQESFNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJL0</accession>
    <name>E3QJL0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Mitochondrial carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_06192</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ31048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095068.1">
        <property type="nucleotide sequence ID" value="XM_008096877.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJL0"/>
    <dbReference type="STRING" id="645133.E3QJL0"/>
    <dbReference type="GeneID" id="24411557"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06192"/>
    <dbReference type="eggNOG" id="KOG0758">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_16_0_1"/>
    <dbReference type="OrthoDB" id="14252at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015227">
        <property type="term" value="F:O-acyl-L-carnitine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902603">
        <property type="term" value="P:carnitine transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006839">
        <property type="term" value="P:mitochondrial transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000060">
        <property type="entry name" value="Mitochondrial carnitine carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF4">
        <property type="entry name" value="CONGESTED-LIKE TRACHEA PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="107"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="255"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="50"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="148"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="255"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ31048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="344" mass="35390" checksum="51F805D83821C467" modified="2011-01-11" version="1">MAPSTSEAAAGVNAKLQSALPNPIADKIPHIPESKGELEADTKAAASGLASQLRSLAAGGFGGVCAVVVGHPFDLVKVRLQTADKGVYSSAVDVVKKSIARDGLRRGLYAGVSAPLVGVTPMFAVSFWGYDVGKTLVRSASSDPSAPLSIAQVSAAGFFSAVPMTAITAPFERVKVILQVQSQRLKPGEAPKYAGGTDVVRQLYAEGGLRSVFRGSAATLARDGPGSAAYFAAYEYIKRRLTPKDPLTGKPTGDLSLLAITAAGAAAGVAMWIPVFPVDTVKSRLQTAEGNVTLGGVVREVYGRGGFKAFFPGFGPALARAVPANAATFLGVELAHQAMNKAFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJL8</accession>
    <name>E3QJL8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NmrA-like family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_06200</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ31056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095076.1">
        <property type="nucleotide sequence ID" value="XM_008096885.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJL8"/>
    <dbReference type="STRING" id="645133.E3QJL8"/>
    <dbReference type="GeneID" id="24411565"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06200"/>
    <dbReference type="eggNOG" id="ENOG502RE6I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_8_6_1"/>
    <dbReference type="OrthoDB" id="3358371at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051164">
        <property type="entry name" value="NmrA-like_oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748">
        <property type="entry name" value="NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748:SF26">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="3"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ31056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="339" mass="37351" checksum="7B1A0EDD81BEB72D" modified="2011-01-11" version="1">MAKKLIAVVGATGNQGGSVARRFLAAGYRVRALTRDSASPSAAALAALGPDLELVHADLEDVVSLEEAFRGANAIFSVTNYWEPFFRPDCRAKAQEQGISCRRFAYDVEYRQGRNIADAAATTVESLDENGFLVSTLSHAARCSGGRFKELYHFDAKADIFPDYVNAKYPALAAKMSCIHTGFFYTSYRILPNSYFRKNPDDTFTMAFTTSPDKPIPHFAPASDMGNFSYAVSQMPPGKAYMAEGTTCTWPQFLKTWAKVTGVKADYKQISPEEMIEATGERDTGIEVAYMFSYSSDPGYDGGMDLLTAADLREAGIDCPMTAWEEWAKQNDWTSVLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJU8</accession>
    <name>E3QJU8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">beta-N-acetylhexosaminidase</fullName>
            <ecNumber evidence="3">3.2.1.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_06280</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.</text>
            <dbReference type="EC" id="3.2.1.52"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 20 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.52" evidence="3"/>
    <dbReference type="EMBL" id="GG697353">
        <property type="protein sequence ID" value="EFQ31136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095156.1">
        <property type="nucleotide sequence ID" value="XM_008096965.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJU8"/>
    <dbReference type="STRING" id="645133.E3QJU8"/>
    <dbReference type="GeneID" id="24411645"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06280"/>
    <dbReference type="eggNOG" id="KOG2499">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010969_1_0_1"/>
    <dbReference type="OrthoDB" id="428480at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004563">
        <property type="term" value="F:beta-N-acetylhexosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06564">
        <property type="entry name" value="GH20_DspB_LnbB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.379.10">
        <property type="entry name" value="Chitobiase/beta-hexosaminidase domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025705">
        <property type="entry name" value="Beta_hexosaminidase_sua/sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052764">
        <property type="entry name" value="GH20_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015883">
        <property type="entry name" value="Glyco_hydro_20_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029018">
        <property type="entry name" value="Hex-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015882">
        <property type="entry name" value="HEX_bac_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43678:SF1">
        <property type="entry name" value="BETA-N-ACETYLHEXOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43678">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00640)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00728">
        <property type="entry name" value="Glyco_hydro_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02838">
        <property type="entry name" value="Glyco_hydro_20b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00738">
        <property type="entry name" value="GLHYDRLASE20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55545">
        <property type="entry name" value="beta-N-acetylhexosaminidase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179806" description="beta-N-acetylhexosaminidase" evidence="7">
        <location>
            <begin position="19"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-hexosaminidase bacterial type N-terminal" evidence="9">
        <location>
            <begin position="114"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 20 catalytic" evidence="8">
        <location>
            <begin position="176"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR625705-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ31136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="716" mass="79002" checksum="63713B1DAC971B3E" modified="2011-01-11" version="1">MAFHRVAAVLCAPALAWGLQLLPPTLERPNSPVEAVWQVASSSKTIYIDDSFASIADTNGLTLIPPSGYDFASLFQQDISQFTGVNWTLQRVDRLPNAANASGIFLGPFNGNASSLAYENGDPTSEGYELDISPMGAFIGGTGARGMWWGTRTLLQLLLSQNGSLPVGRVVDAPAYATRGFMLDAGRKWYAPGFLKELCSYASFFKMSEFHYHLSDNYPLNRGRNESWQDVYSHFSLRPEDESLLPILHGRENETLSREDFASLQSHCAARGITIIPEIEAPGHCLYLTKWKPELSLAKRDLLNLSHPEAIPIVKRIWSEFLPWFETKEVHVGADEYDATLADVYIGFVNEMSDFINSTTGKRIRIWGTYEPSENVTISRDVIIQHWQYGQSDPVLLTDTGYNIINSEDWWAYMSLKNDHMPILPAKYPQFFNESRVLNFADEPGWQWTPADFNPFNKTMQIPDGSPSNGGAIMAAWNDNGPDASTQLEAYYAMRRGIALTGARAWSGRRGPELVEDDVAPSIDFFSPLAPGQNLDRTLPSPSAPAPLVTWNRSVDDTETVHLGHGSKGINYTLSLFFGGPFTLTGPDSTLSLDGNGSLTFSADGWVYPLRSVSERDALDLDPGHPGRIWANVSTSSHEVVKLSTLPANVTIATDSLHGSIAWIDGQFVGRFEVFVYGGRNTLFSWSQMAFVAPLESTTGPGLQSLVVEGDMNLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QK80</accession>
    <name>E3QK80_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_06412</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697354">
        <property type="protein sequence ID" value="EFQ31268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095288.1">
        <property type="nucleotide sequence ID" value="XM_008097097.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QK80"/>
    <dbReference type="STRING" id="645133.E3QK80"/>
    <dbReference type="GeneID" id="24411777"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06412"/>
    <dbReference type="eggNOG" id="ENOG502T62W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057356_0_0_1"/>
    <dbReference type="OrthoDB" id="5235746at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="301" mass="30709" checksum="CD9BBFB584C8C771" modified="2011-01-11" version="1">MDPVPVAAPAPAANGADKVAETVATTTSADTKATEPPVAEMKPAEEKKDEKKEETAPVPETSAAAPVDESTKPEEPSALAPPADAPATADITVDAPKPASVEEVPDQDGPASTGVREPDPTPVEQPAVTSAPTDEPVKASVEAPIAQEPAKAPVAEDEPIKEPIIDKTEAVNGDATKGVEMTGALNDAEPADAGEGEAAPQVIPPEPKVGDKRKADDSVETNGANGAHGTDGTNGVGETLEEKPAEKKAKRGPGRPPSNGAAKESSKKEKESLGHKVARNVKKVIHPVGRTARKTRSQGPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>E3QL39</accession>
    <name>E3QL39_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Bifunctional cytochrome P450/NADPH--P450 reductase</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="16">Cytochrome P450</fullName>
                <ecNumber evidence="16">1.14.14.1</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="16">NADPH--cytochrome P450 reductase</fullName>
                <ecNumber evidence="16">1.6.2.4</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="21" type="ORF">GLRG_06866</name>
    </gene>
    <organism evidence="22">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15 16">
            <text>2 oxidized [cytochrome P450] + NADPH = 2 reduced [cytochrome P450] + NADP(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24040"/>
            <dbReference type="Rhea" id="RHEA-COMP:14627"/>
            <dbReference type="Rhea" id="RHEA-COMP:14628"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:55376"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="EC" id="1.6.2.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 16">
            <text>an organic molecule + reduced [NADPH--hemoprotein reductase] + O2 = an alcohol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17149"/>
            <dbReference type="Rhea" id="RHEA-COMP:11964"/>
            <dbReference type="Rhea" id="RHEA-COMP:11965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:142491"/>
            <dbReference type="EC" id="1.14.14.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <cofactor evidence="16">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 16 17">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">In the N-terminal section; belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EC" id="1.14.14.1" evidence="16"/>
    <dbReference type="EC" id="1.6.2.4" evidence="16"/>
    <dbReference type="EMBL" id="GG697356">
        <property type="protein sequence ID" value="EFQ31577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095597.1">
        <property type="nucleotide sequence ID" value="XM_008097406.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QL39"/>
    <dbReference type="STRING" id="645133.E3QL39"/>
    <dbReference type="GeneID" id="24412231"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06866"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_7_0_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070330">
        <property type="term" value="F:aromatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003958">
        <property type="term" value="F:NADPH-hemoprotein reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06206">
        <property type="entry name" value="bifunctional_CYPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11068">
        <property type="entry name" value="CYP120A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000040">
        <property type="entry name" value="Bifunctional cytochrome P450/NADPH--P450 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000198">
        <property type="entry name" value="Bifunctional cytochrome P450/NADPH--P450 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000031">
        <property type="entry name" value="Bifunctional cytochrome P450/NADPH--P450 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023206">
        <property type="entry name" value="Bifunctional_P450_P450_red"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF127">
        <property type="entry name" value="BIFUNCTIONAL CYTOCHROME P450_NADPH--P450 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000209">
        <property type="entry name" value="Bifunctional_P450_P450R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 16" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8 16" id="KW-0274">FAD</keyword>
    <keyword evidence="5 16" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 16" id="KW-0288">FMN</keyword>
    <keyword evidence="4 16 17" id="KW-0349">Heme</keyword>
    <keyword evidence="12 16 17" id="KW-0408">Iron</keyword>
    <keyword evidence="7 16 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13 16" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9 16" id="KW-0521">NADP</keyword>
    <keyword evidence="11 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 16" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="19">
        <location>
            <begin position="510"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="20">
        <location>
            <begin position="688"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="479"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="17">
        <location>
            <position position="411"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR000209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR000209-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EFQ31577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1081" mass="120770" checksum="BFD790704601A90F" modified="2011-01-11" version="1">MSGEIEIPEPSRIPVLGHVTEIDTEYSLGSFVHLANKFGPIYKLDLLGQKLVFLNTHELINECCDDKRFKKSIEGDLNELREAVHDGLFTSKGVEEENWGVAHRVLMSAFGPLAIRDMFDPMHDVAGQLAMKWARHGPSTPIHIGEDMTRLAMDTVALCTMGYRFNSYYREDTHPFITAMYAVMKEAGDKSFRVLPQVFYKKQDKKMKANIKLLRSTAKEVLDARRLDPNGATGRKDVLTAMLNTVDPVTGRKMTDDSIVDNLITFLVAGHETTAATLTFTMYWLLKRPEVYRKVQEEVDNTVANGPLRVEHVAKLKYLTAVIREVLRHSAPIYAFGREVLKGEEVIGGKYRIKPGDQILCFLAKSHLDPKVYGDDAEEFKPERMLDENFDRLMKEFPNCWSPFGTGMRGCIGRAFAWQEMVLALALLLQNFNFVMHNPNYDLKISQTLTIKPKDLYVRAILREGLTPSSLEARMAGSYSAGHGAQPKTTAHEATDGSSEANGIKEKAKLAVFYGSNSGTCEFMAQRLASDAASHGFSATVDTLDTARESLPADRPVVIITSSYEGEPPHNAALFVDWLTNLKGKELKNVKYAVYGCGHADWVKTHQRIPKLVDASIEERGGHRIVPFASTDAKDRDMFSDFEAWEDDTLWPALVKQFDGQPEGEDSSIPEAGLSVSFSTPRTSTLRQDVRDALVLDSRPLANGDLGPVKRHLEVQLPSNVRYTAGDYMAVLPHNPKDTVARVMRHFHLTWDSHVTIKAAGPTTLPTDASIPVSDVLSSYVELCQTASRRNISTLSQFAKDEELRRKLQYLATDGYDVGVKNKRLSVLDIAEHFPSLAIPFNHFLLMLPPMRVRQYSISSSPLVEPGVATITYGVLDEPALSGQGRHIGVTSSYLSSLAAGDRIQVSIRVAQGGFKLPIDVDKTPLLCVAAGTGLAPFRAFIQERATLLSNGRQLAPAILFFGCRHPLADDLYRDEFDKWEAAGAVKMYRAYSRKPDASSGCKYVQDRIWREREMLYDLWDQGARVYVCGSNKVAEGVKDVLLRAAREKSEIDDGKPMTEEELEEWFNGIRNERYATDVFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLB6</accession>
    <name>E3QLB6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Eukaryotic aspartyl protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">GLRG_06943</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase A1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697356">
        <property type="protein sequence ID" value="EFQ31654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095674.1">
        <property type="nucleotide sequence ID" value="XM_008097483.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLB6"/>
    <dbReference type="STRING" id="645133.E3QLB6"/>
    <dbReference type="MEROPS" id="A01.077"/>
    <dbReference type="GeneID" id="24412308"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06943"/>
    <dbReference type="eggNOG" id="KOG1339">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013253_10_1_1"/>
    <dbReference type="OrthoDB" id="660550at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000085">
        <property type="entry name" value="Aspartic-type endopeptidase (CtsD), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000060">
        <property type="entry name" value="Aspartic-type endopeptidase ctsD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF75">
        <property type="entry name" value="ENDOPEPTIDASE (CTSD), PUTATIVE (AFU_ORTHOLOGUE AFUA_4G07040)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 16" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179846" evidence="14">
        <location>
            <begin position="19"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="15">
        <location>
            <begin position="140"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="445"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="453"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="469"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="493"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="338"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="171"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EFQ31654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="537" mass="56968" checksum="627EDC27CE902002" modified="2011-01-11" version="1">MRSATLVYLSLLFTSTHAFFPWPSPECLEKGDCVLPTKRQLKGQDELRSDVVDAVKAINLPASQLGPQATHDFSTKDAESERVVREVERLTRKYARFQSAAVREKALRSKRESQYRIVKAADTKLKNAVGVAQDGTDFSYFAQVKLGNNKKPMWMLMDTGAGTSWVMGSSCKSAACEKHGSFGPPDSATYKATGETFSVAYGSGSVKGDKVTDTLSFAGMNFNFQFGVANETSDDFNHFPFDGILGLSMAGGETENFMQVVKNSTQLPANIFCVYLSRAADGPNTSEISFGVCNPDKYTGDITYTAVGNALGDWAVPLDGIAYDGLKSGAAGKLAYIDTGTSYVFGPKDDVAAFHKNIPGSTADEAGTTYKVPCDSNKDVTYTFSNISYVISAKDWRGVPGTDGTCTSNIYGHEVVTGAWLLGDVFLKNVYAVFDTDQKRIGFAKRVDPPPVTTTSSSDTSATPPVVGNSDNANIGTPVQTSKPGLGLGGHETTASATAAAQTSPVSHSGAASSASLTVVKAATVATFCLVALLGFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLU0</accession>
    <name>E3QLU0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">N-alpha-acetyltransferase 40</fullName>
            <ecNumber evidence="4">2.3.1.257</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_06972</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N-terminal L-seryl-[histone H2A] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-seryl-[histone H2A] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50600"/>
            <dbReference type="Rhea" id="RHEA-COMP:12742"/>
            <dbReference type="Rhea" id="RHEA-COMP:12744"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:64738"/>
            <dbReference type="ChEBI" id="CHEBI:83690"/>
            <dbReference type="EC" id="2.3.1.257"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>N-terminal L-seryl-[histone H4] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-seryl-[histone H4] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50596"/>
            <dbReference type="Rhea" id="RHEA-COMP:12740"/>
            <dbReference type="Rhea" id="RHEA-COMP:12743"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:64738"/>
            <dbReference type="ChEBI" id="CHEBI:83690"/>
            <dbReference type="EC" id="2.3.1.257"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the acetyltransferase family. NAA40 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.257" evidence="4"/>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095848.1">
        <property type="nucleotide sequence ID" value="XM_008097657.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLU0"/>
    <dbReference type="STRING" id="645133.E3QLU0"/>
    <dbReference type="GeneID" id="24412337"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06972"/>
    <dbReference type="eggNOG" id="KOG2488">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051699_2_1_1"/>
    <dbReference type="OrthoDB" id="424551at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043998">
        <property type="term" value="F:histone H2A acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010485">
        <property type="term" value="F:histone H4 acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990189">
        <property type="term" value="F:protein N-terminal-serine acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039949">
        <property type="entry name" value="NAA40"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20531">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20531:SF1">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="13">
        <location>
            <begin position="87"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="18"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="113"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ31828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="252" mass="28159" checksum="8A5E29C07D55345E" modified="2011-01-11" version="1">MAPLRKRRRAPTNPIEAANRKPDDQFIKDHLRPSPDWTLWTHPASGKPYALSLKSAPALAQHELQACFDLVERTSGADYRASRDGWRPLAKLKEMRSPELRYIVVKEAPAPDGGDDDDDDDDGEKANVEEGRICGFTSLMPTFEEGEAVVYCYEIHLVEELRGTGMGRGLMDHLVRVAESIPGVEKVMLTCFVANAGARAFYERLGFERDAISPPERTLRSGTVFVPDYLIMSRRVVRGPARTETMGKRDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLY9</accession>
    <name>E3QLY9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Unsaturated glucuronyl hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_07021</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 88 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095897.1">
        <property type="nucleotide sequence ID" value="XM_008097706.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLY9"/>
    <dbReference type="GeneID" id="24412386"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07021"/>
    <dbReference type="eggNOG" id="ENOG502SH7S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027158_2_0_1"/>
    <dbReference type="OrthoDB" id="2317065at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052757">
        <property type="term" value="F:chondroitin hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.10:FF:000048">
        <property type="entry name" value="Unsaturated chondroitin disaccharide hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052369">
        <property type="entry name" value="UG_Glycosaminoglycan_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36845">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G05090)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36845:SF1">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G05090)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ31877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="516" mass="57560" checksum="7C92A875B8AAC028" modified="2011-01-11" version="1">MAQLINPDIALEGGLSTVNDTAHATLDSTTESNIDRDTSNSEPSGRLQADHKRKIGQLKPFRAPLGGLYEENITAKILRTAEDGLVDNNPPTAYPEYVLQRGPDAGKYILREVFFWTCGFFPGSIYSLIERVVKFPHKMPVGHEKTALLSKLWSLGAAWSEPLHTTAKRTDTHDMSFMIQPSMRVRWEVAQDRQALDSIIKAAKALHTRFNPTVGAIRSWDALTQRGVTIASLTDDFLVIIDSMCNLDLLYYASSCTGESHLWDAATKHAKTLIKSNLRSEKDPRGLVRGELYSTIHVINFDPKNGEIKGRRTAQGYAAESTWARGQAWAILGYAQTFMWTGDNESLDVARGLSEYFILRLETPANSVELPVEGEDRTKGRYVPLWDFDAPIEIENSPLRDSSAGVIAANGMPVLSQALAGQGRTEESARYRDMAITIANDTLELSLATEKATLVFENGKFSVKDVEKGDTFDALLKNATANRNRRDRKQYWDHGLVYGDYYLIEFGNRMLKMGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3QM23</accession>
    <name>E3QM23_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07055</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095931.1">
        <property type="nucleotide sequence ID" value="XM_008097740.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QM23"/>
    <dbReference type="GeneID" id="24412420"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07055"/>
    <dbReference type="HOGENOM" id="CLU_2037891_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="121" mass="13320" checksum="B834FC50AD1E1455" modified="2011-01-11" version="1">MSLPTGTSPSTRNSTPFLSAAAAAVLRDLRIAPIRRPISTAAVGKCSKPSAQHRSTKCIHHPRVHVPGLDGLHHRVHNVCKVRKVALAFNILWVFIVHWRLLMIQDPLAGPWASLIFGQKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QM80</accession>
    <name>E3QM80_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Autophagy-related protein 28</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_07112</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095988.1">
        <property type="nucleotide sequence ID" value="XM_008097797.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QM80"/>
    <dbReference type="STRING" id="645133.E3QM80"/>
    <dbReference type="GeneID" id="24412477"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07112"/>
    <dbReference type="eggNOG" id="ENOG502SANW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015530_1_0_1"/>
    <dbReference type="OrthoDB" id="5342758at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="185"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="556"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="319"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="114"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="642"/>
            <end position="654"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ31968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="654" mass="72460" checksum="D79879A8D6B62FC4" modified="2011-01-11" version="1">MAPGSPRFLDRLSPTRQKSPILPLYTSHARRSNDYDLDDLSPRLDEALLPELPRSPITMSRRRSPSPADPWDDHTPSPAGSVSKMKPKAMFAGPPPPIATSVLLQPPASQTSRTSRDGTVDTEKRTKGITASQVMFGSIFFDHDSRDQSISRVDSVWRNLQHRERSLQKEVQRLLDMQATGLVSGSESLEPNAGGPETWSDSGSSTPTGTFYSTATSKSRMMASLDPPVRATPRGDIIPVRQPKSSGPQGLRAARNGLRRVLAALTELKAEENDYIESSLSQRKKALEYLGNLDARRTSISAELHSLADDEEEPLAKELRGLGEQHGSLGQEIRQLEEKLIGMRNRQRWLERKMEDVRNRREAGLSGYRGALKEVEGEVASLLRRPPIEPLDLEVVEATTRNEPGNAINPQDPPGGADFFRMIPARRTLSMAKDWWESETDLLLKRKMQVAKDRDALEQGTELWQETIKLVTSFEADLRQSLSDGSSATVKGKQPQRAGLEGVEALLPRMGKVILELEEHVRTAERNSWNLLICAIGAELEAFREAEGLLRASLPQSQAAPRVADVQEPWPNDDGLPHQSTQADPGEACTARSHHEESDNEVPPDLLVSRLEEHDDGHSLIGSLQTSSSRRGSENEVPPEFLAEHDNEHDGNMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMH6</accession>
    <name>E3QMH6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Glycosyltransferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_07208</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096084.1">
        <property type="nucleotide sequence ID" value="XM_008097893.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMH6"/>
    <dbReference type="STRING" id="645133.E3QMH6"/>
    <dbReference type="GeneID" id="24412573"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07208"/>
    <dbReference type="eggNOG" id="ENOG502SICP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019940_2_1_1"/>
    <dbReference type="OrthoDB" id="2849215at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052427">
        <property type="entry name" value="Glycosyltrans_GT2/GT47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47844:SF1">
        <property type="entry name" value="EXOSTOSIN-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47844">
        <property type="entry name" value="SYNTHASE CPS1, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G02500)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13641">
        <property type="entry name" value="Glyco_tranf_2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="327"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ32064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="433" mass="49296" checksum="DC7FE0C173D7213C" modified="2011-01-11" version="1">MINIWGSWRYTATPVSRHPTWGRRDVTVILPTIDVDNPKFDECILSILENRPAAVLIVTVGAGMRARSEAAARAYRREYPSTEIGVSAILHPSKRRQVAHAVGHVRTEFTVLADDHVFWPSRDFLPSALAPFEDVNVGIVATHKRVRRTTPGEWSMSSIINLIGCLYLLRHNWELRASNAIDGGVFVVSGRTALYRTRLLRSSGLMRRFCNEHFFFGLFGGKEGLGPDDDNFLTREAYRHGWDIKFQQTKDCTIETTLGDESAVKFRGQLIRWARTTFRSNPCMLIRVSDFSTWRMPFTYFAVYGAALFNFALLWDAALILSLARSTWSDGLFSVSVFKLVLWILWSKTIKLWPHILRHPADIPLLTCQIIFAYVHSVIKLWACITFWDCAWSGRNLNAVDAESKISKEYLDQGFDFGTVADEPGLPRHTIYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMN7</accession>
    <name>E3QMN7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Peptidase family M3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_07269</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the peptidase M3 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096145.1">
        <property type="nucleotide sequence ID" value="XM_008097954.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMN7"/>
    <dbReference type="STRING" id="645133.E3QMN7"/>
    <dbReference type="MEROPS" id="M03.009"/>
    <dbReference type="GeneID" id="24412634"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07269"/>
    <dbReference type="eggNOG" id="KOG2089">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001805_1_1_1"/>
    <dbReference type="OrthoDB" id="534666at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006518">
        <property type="term" value="P:peptide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06455">
        <property type="entry name" value="M3A_TOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1050.40:FF:000001">
        <property type="entry name" value="Thimet oligopeptidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.390.10:FF:000006">
        <property type="entry name" value="Thimet oligopeptidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.40">
        <property type="entry name" value="Endopeptidase. Chain P, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.10">
        <property type="entry name" value="Neurolysin, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024077">
        <property type="entry name" value="Neurolysin/TOP_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024080">
        <property type="entry name" value="Neurolysin/TOP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804">
        <property type="entry name" value="PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804:SF84">
        <property type="entry name" value="SACCHAROLYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4 9" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M3A/M3B catalytic" evidence="10">
        <location>
            <begin position="224"/>
            <end position="698"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ32125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="701" mass="79233" checksum="83F003528CC4DAE2" modified="2011-01-11" version="1">MTVPDKYKSPPQAPPVFTGTKESIVGDAKKICDQTRALLDKIVAEVPADKAAFDNVLQPIARDENESGLSTRILGFYQYVSSDAALREASSQADTIMDEFGIEVNMREDVYKLIEALHNKKDSEGLDPESLRLLEKDYKNYIKMGLGLPAGPQRDRFKEIKKRLSQIQIEFQKNLNEENGGIWFTPEELDGVPEDVIDGLEKGTGENEGKLKLSFKYPDLFPTLKFAKNAETRRKVFIQNENKCNQNVPLFKEAIVLRDEAARMLGYPDHASLRIEDKMAKTTKTVNDFLADLRSRLTAGGAKEVQHLLELKKADTEARGVANDGNYYLWDHKFYDRLMIEKEYSIDENKIAEYFPITSTIAGMLKIFEELLGFVFVELKPEDRKALSPTGKGEDIAWHEDVIIFSVWDDASEGEGFVGYLYLDLHPRQGKYGHAANFNLQPGYLQANGSRRYPATALVCNFSKPTPKKPSLLKHDEVVTLFHELGHGIHDLAGRCTYSRFHGTSTVRDFVEAPSQMLENWCWTPSVIKALSQHYQTGEKIPDDLIEKQISTKHVNAALFNLRQLHFGTFDMTVHTPKSHEEIKNMDLSSVYNELRGQIAGIKGPEAQGEKSTWGNGQACFGHLIGGYDAGYYGYLSSEVYSTDMFYSVFKADPMNGKEGRRYRHTVLEKGGSQEEMLTLEQFLGRKPSTESFYKELGIPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QND9</accession>
    <name>E3QND9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">C2H2 transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_07521</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697361">
        <property type="protein sequence ID" value="EFQ32377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096397.1">
        <property type="nucleotide sequence ID" value="XM_008098206.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QND9"/>
    <dbReference type="STRING" id="645133.E3QND9"/>
    <dbReference type="GeneID" id="24412886"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07521"/>
    <dbReference type="eggNOG" id="ENOG502SNWP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036929_0_1_1"/>
    <dbReference type="OrthoDB" id="5305647at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059009">
        <property type="entry name" value="Znf_C2H2_17_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059095">
        <property type="entry name" value="Znf_C2H2_17_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF24">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26177">
        <property type="entry name" value="zf_C2H2_17_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26176">
        <property type="entry name" value="zf_C2H2_17_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="207"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="230"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="76"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="90"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="233"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ32377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="333" mass="36688" checksum="5006F32470AB9181" modified="2011-01-11" version="1">MSVVYEPRNFMHDGSYPPIGDPDHDHNVDPTGQYQATDVPDLASYNPTASMLGDDRSLMPEGLDDGSVGVPDATRLDLSAPPTLASLPSQLPPALPEPLPSNNKDDGEASTPSSRVKCIPKPEREVTKQADGKFYCTFPGCTEETQVFTRKCEWSKHMDKHERPYRCAAEGCEKLPGFTYSGGLLRHEREVHGKHGGPKNTVNCPHPNCKRHTGKGFSRQENLNEHLRRVHTSDGSSTVQEDIQTGSDGDSEKAGIFGAGNKRKRSRKSSDAGLDELREEIKRVRQENEELRQQLDRQGQHSFAMMTQIAELQDALRTNLDGTGLGAPTATML</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNH7</accession>
    <name>E3QNH7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Beta-glucosidase cel3A</fullName>
            <ecNumber evidence="5">3.2.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Beta-D-glucoside glucohydrolase G</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="20">Beta-D-glucoside glucohydrolase cel3A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Cellobiase G</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="22">Cellobiase cel3A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="18">Gentiobiase G</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="21">Gentiobiase cel3A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">Probable beta-glucosidase G</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">GLRG_07734</name>
    </gene>
    <organism evidence="26">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="26" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="26">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="5"/>
    <dbReference type="EMBL" id="GG697362">
        <property type="protein sequence ID" value="EFQ32464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096484.1">
        <property type="nucleotide sequence ID" value="XM_008098293.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNH7"/>
    <dbReference type="STRING" id="645133.E3QNH7"/>
    <dbReference type="GeneID" id="24413099"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07734"/>
    <dbReference type="eggNOG" id="ENOG502QR4D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004542_2_3_1"/>
    <dbReference type="OrthoDB" id="416222at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000757">
        <property type="entry name" value="Beta-glucosidase G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.300:FF:000002">
        <property type="entry name" value="Probable beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1700:FF:000003">
        <property type="entry name" value="Probable beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF12">
        <property type="entry name" value="BETA-GLUCOSIDASE G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="8 25" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0964">Secreted</keyword>
    <keyword evidence="7 23" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="23">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179876" description="Beta-glucosidase cel3A" evidence="23">
        <location>
            <begin position="21"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type III-like" evidence="24">
        <location>
            <begin position="729"/>
            <end position="801"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00024983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00039579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00041276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00041601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00041808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00070030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00078013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00083231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00083611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="EFQ32464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="815" mass="88169" checksum="26E2AD8EA57C03B0" modified="2011-01-11" version="1">MSAALSLFLSGLLLAPSVSAQAYDAGERADDAFSYIQPLNTTILGPYGHSPAVYPSPNTTGSGWEDALAKARAFVAQLTIEEKANVVTGQPGPCVGNIIPIPRLGFQGLCLQDGPLSIRVADYASVFSAGVSAASTWDKDILYERGLALGKEFRAKGAHIALSPVAGPLGRSAYSGRNWEGFSPDPYLTGVAMYQTITGHQDAGVQATAKHWILNEQETMRNPTFDPNGTSTDIVEQAISSNVDDRTIHELYMWPFADAVKARAAAFMCSYQRINGSYGCQNSKSLNGLLKTELGFDGYVMSDWGATHTGVAAIEAGLDMDMPGGLGTYGMNWASGSFFGGNVTTAVNNGTLDVSRVDDMILRIMTPYYWLGQDKDYPTIDASSGDLNTFSPKSTWTYNYTFTGERSRDVRGNHGELIRKHGAAATILLKNENKALPLKAPKSIAVFGNDASEDTQGLLNQNDFEYGTLSSGGGSGTGRLTYLVTPLEAIKARAAKDGALVQQWLNNTQLATTDITTLWIPKLPEVCLVFLKTWAEEAADRQHLDVDWNGNDVVESVAKSCNNTIVVTHSSGINTLPWADHPNVTAILAAHYPGQESGNSLVDVLYGDVNPSARLPYTIALNGSDYNAPPTTAINTTGSYDWQSWFDEKLEIDYRYFDARNMSVRYEFGFGLSYTTFELANFEASPVEDNITSVPEQRPIEPGGNPALWDTIYNATASITNTGEVEGAAVPQLYVTFPADTTPAGTPPKQLRGFEKVPLAASETKNVGFPLMRRDLSYWDVVSQQWLIPAGEFTLSVGWSSRDLKAFAKITPVQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNV9</accession>
    <name>E3QNV9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">COP9 signalosome complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_07561</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">Component of the COP9 signalosome (CSN) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CSN2 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697363">
        <property type="protein sequence ID" value="EFQ32547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096567.1">
        <property type="nucleotide sequence ID" value="XM_008098376.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNV9"/>
    <dbReference type="STRING" id="645133.E3QNV9"/>
    <dbReference type="GeneID" id="24412926"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07561"/>
    <dbReference type="eggNOG" id="KOG1464">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028981_0_1_1"/>
    <dbReference type="OrthoDB" id="194139at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008180">
        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.570:FF:000006">
        <property type="entry name" value="COP9 signalosome complex subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050871">
        <property type="entry name" value="26S_Proteasome/COP9_Components"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10678">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00753">
        <property type="entry name" value="PAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0736">Signalosome</keyword>
    <feature type="domain" description="PCI" evidence="10">
        <location>
            <begin position="252"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="465"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="476"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ32547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="493" mass="56309" checksum="A0BC320AC4BC9E77" modified="2011-01-11" version="1">MSDDEDFMQESDEEQYDFEYEEDDEEDSGDVGIENKYYNAKQLKLTDPEDAIAEFLGIPPLEDEKGEWGFKGLKQAIKLEFKLGQYEKATEHYAELLTYVKSAVTRNYSEKSINNMLDYIEKGSDGPKAVACVEKFYSLTLESFQSTNNERLWLKTNIKLAKLLLDRKDYNIVTKKLRDLHKACQKEDGSDDPSKGTYSMEIYALEIQMHAETKNNKQLKRLYQRALKVRSAVPHPKIMGIIRECGGKMHMSEENWVEAQTDFFESFRNYDEAGSLQRIQVLKYLLLTTMLVKSTINPFDSQETKPYKQDPRITAMTELVDAYQRDDVHAYENVLQKNQDILADPFIAENIDEVTRNMRTKGVIKLIAPYTRMKLGWIAKQLKISEPEVQDILGFLIVDGKIDGKIDQQAGTLEIQSDADSDRTKALYELTQSVSSLYATVFKEGDGFRSTDFPTDEQAMELIGGGMTPRSGGLRGHPRGPGRKGKGVMPLWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QP97</accession>
    <name>E3QP97_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosomal protein S14p/S29e</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_07829</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS14 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697364">
        <property type="protein sequence ID" value="EFQ32685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096705.1">
        <property type="nucleotide sequence ID" value="XM_008098514.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QP97"/>
    <dbReference type="STRING" id="645133.E3QP97"/>
    <dbReference type="GeneID" id="24413194"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07829"/>
    <dbReference type="eggNOG" id="KOG1741">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139869_2_0_1"/>
    <dbReference type="OrthoDB" id="413436at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.1480:FF:000001">
        <property type="entry name" value="30S ribosomal protein S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001209">
        <property type="entry name" value="Ribosomal_uS14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018271">
        <property type="entry name" value="Ribosomal_uS14_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006477">
        <property type="entry name" value="PRK08881.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19836">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19836:SF19">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US14M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00253">
        <property type="entry name" value="Ribosomal_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00527">
        <property type="entry name" value="RIBOSOMAL_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ32685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="113" mass="13465" checksum="1F8655016009BF72" modified="2011-01-11" version="1">MSMFRAKKLDLGCFINIRTIRDHTKRQVFMEHEPERQALRYIIRNTTLPPRVRAEAQLQLGQMHCYTRPTQIRNRCVMGGKSRGVFREFKMSRFNFRMQAYEGNLPGVKKASW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPA0</accession>
    <name>E3QPA0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07832</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697364">
        <property type="protein sequence ID" value="EFQ32688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096708.1">
        <property type="nucleotide sequence ID" value="XM_008098517.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPA0"/>
    <dbReference type="GeneID" id="24413197"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07832"/>
    <dbReference type="HOGENOM" id="CLU_2320211_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="99" mass="11715" checksum="6D9180999D8DB7CF" modified="2011-01-11" version="1">MDNSRFFPSSSSLLNQERTETEEETNPWNLQKRTRKKEVVAWMERVPQTEFPAVSLTVSRYHRSETCDSFVGILSRRCLSFCWGNRISHCLVVRRWTGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPH7</accession>
    <name>E3QPH7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NUDIX domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_07909</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697364">
        <property type="protein sequence ID" value="EFQ32765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096785.1">
        <property type="nucleotide sequence ID" value="XM_008098594.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPH7"/>
    <dbReference type="STRING" id="645133.E3QPH7"/>
    <dbReference type="GeneID" id="24413274"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07909"/>
    <dbReference type="eggNOG" id="KOG3041">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062658_0_1_1"/>
    <dbReference type="OrthoDB" id="10249920at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047631">
        <property type="term" value="F:ADP-ribose diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006753">
        <property type="term" value="P:nucleoside phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019693">
        <property type="term" value="P:ribose phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd18888">
        <property type="entry name" value="NUDIX_ADPRase_Nudt5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.79.10:FF:000016">
        <property type="entry name" value="ADP-sugar pyrophosphatase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11839:SF1">
        <property type="entry name" value="ADP-SUGAR PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11839">
        <property type="entry name" value="UDP/ADP-SUGAR PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="3">
        <location>
            <begin position="47"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ32765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="200" mass="22246" checksum="B1920CBBC1546B39" modified="2011-01-11" version="1">MAAVTKTSPLSDDEARWIKLVKINYKDQNGQARTWESAERRTRPKNGEIDGVGIVAILEKPTGPEIVLQKQYRPPIDKVTIEVPAGLVDEGETAEEAAVRELKEETGYVGKASETTPIMFNDPGFCNTNLRMIHVTIDTSLPENQNPKAELEEGEFIEVFTVPLAKFWDECVRLEAEGYAIDARVGTIAEGIELAKKFKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPQ9</accession>
    <name>E3QPQ9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_07980</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697365">
        <property type="protein sequence ID" value="EFQ32836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096856.1">
        <property type="nucleotide sequence ID" value="XM_008098665.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPQ9"/>
    <dbReference type="STRING" id="645133.E3QPQ9"/>
    <dbReference type="GeneID" id="24413345"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07980"/>
    <dbReference type="HOGENOM" id="CLU_2249929_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ32836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="104" mass="11728" checksum="3C28C4796ECAA449" modified="2011-01-11" version="1">MQNMLVIMASRSEFDDLLANGITPIQQFDSNKEGVPHGPERDTYWLCSMPWGGRSRSAGPRTGEHGWRPDDVLEDQFWVDFSNAYLTEAAKAPQGSRRSTSYFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPZ6</accession>
    <name>E3QPZ6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">Peroxisomal membrane protein PEX14</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 7">Peroxin-14</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_08078</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor. The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm. Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6 7">Peroxisome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peroxin-14 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697366">
        <property type="protein sequence ID" value="EFQ32934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096954.1">
        <property type="nucleotide sequence ID" value="XM_008098763.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPZ6"/>
    <dbReference type="GeneID" id="24413443"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08078"/>
    <dbReference type="eggNOG" id="ENOG502S3Q3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044743_0_0_1"/>
    <dbReference type="OrthoDB" id="441517at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990429">
        <property type="term" value="C:peroxisomal importomer complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005102">
        <property type="term" value="F:signaling receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016560">
        <property type="term" value="P:protein import into peroxisome matrix, docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025655">
        <property type="entry name" value="PEX14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006785">
        <property type="entry name" value="Pex14_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23058">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23058:SF5">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04695">
        <property type="entry name" value="Pex14_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0811">Translocation</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Peroxisome membrane anchor protein Pex14p N-terminal" evidence="9">
        <location>
            <begin position="43"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="71"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="222"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="128"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00046271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ32934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="382" mass="41647" checksum="DE2782EB89286F3F" modified="2011-01-11" version="1">MSDSDDNKSTPGIPEWQRDQKTDAELEPQTQQPSQDAVPNEPTRENSIEIARKFLQDDEIKDAPREVKEAFLKTKGISSTDIEELLGSSVPEPAHDTTQTDQTSASSTQVAATTTPKSQEVPTPPPNNEVSIPRQTDQPPVVTYPEFLTKSTRPPPLVTANGILNTLYAFAGLSTLLYGTSKYVVAPMVETLTEARCDLHDTTSKNLAKIIEKLEGAVSEVPAPKATAGNGEAYRDDASSSSADDPTEMFHRDIGTQTSVPPTPRFGEPGFGMTGTAAEHRNRSASDWQADKLARLKSSADLLKTTVVSDAEDLADLKSRMDVLKDDLVQLAYPSPQDYGSYSLYGGPRKNEPEDEIKKARDNIRRVKGVLLSTRNFPASSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRC2</accession>
    <name>E3QRC2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">TatD family hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_08689</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697370">
        <property type="protein sequence ID" value="EFQ33410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097430.1">
        <property type="nucleotide sequence ID" value="XM_008099239.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRC2"/>
    <dbReference type="STRING" id="645133.E3QRC2"/>
    <dbReference type="GeneID" id="24414054"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08689"/>
    <dbReference type="eggNOG" id="KOG3020">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031506_1_0_1"/>
    <dbReference type="OrthoDB" id="6079689at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008296">
        <property type="term" value="F:3'-5'-DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01310">
        <property type="entry name" value="TatD_DNAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018228">
        <property type="entry name" value="DNase_TatD-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050891">
        <property type="entry name" value="TatD-type_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10060:SF15">
        <property type="entry name" value="DEOXYRIBONUCLEASE TATDN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10060">
        <property type="entry name" value="TATD FAMILY DEOXYRIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01090">
        <property type="entry name" value="TATD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="298"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ33410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="383" mass="42467" checksum="91ED1C3804BFED8B" modified="2011-01-11" version="1">MATPAESPQSAYQPRYIDIGINLADPIFRGLHHGKQRHPDDLEGVISRAKEVGCSKLIVTGSDFTSSRDALEIAKQYPGVVYTTIGIHPCSSAVFSSSGEAAEGMHTDPDPSKPIPDTHEPDPTKTEAIISELRDLIKDSTASKSGLVAFGEFGLDYDRLHYCSKTIQLHSFAAQLDLVLETKPQLPLFLHSRAAHDDFVRLLKEKFGERLENLEKGGVVHSFTGTIEEARELMDLGLYIGINGCSFKTQENCEVVRQIPLDRMMIETDGPWCEIRPSHFGFKYLIEKKPEANGTMDGAAIQEPAQGPPQGKKRSHKKEPEVPERFKVVKKEKWEEGAMIKGRNEPCMIERVAKAVAGIKGVEVEDICEAAWRSTVKVFAVDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRC7</accession>
    <name>E3QRC7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Mitochondrial carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_08694</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697370">
        <property type="protein sequence ID" value="EFQ33415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097435.1">
        <property type="nucleotide sequence ID" value="XM_008099244.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRC7"/>
    <dbReference type="STRING" id="645133.E3QRC7"/>
    <dbReference type="GeneID" id="24414059"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08694"/>
    <dbReference type="eggNOG" id="KOG0758">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_4_0_1"/>
    <dbReference type="OrthoDB" id="2382881at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF9">
        <property type="entry name" value="CARRIER PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G06390)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="66"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="200"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="244"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="13"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="122"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ33415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="332" mass="37154" checksum="634A408564C61E6F" modified="2011-01-11" version="1">MPRAQEERPQRLVKRYRTEIAASTSSMFSTVVAFPLDSVKTRMQTYRYDGFLDCVRHTYRTEKLRGFFRGVLAPMASITLVRTMSFSIYQRAKYSYSGWIKNALGFDVLQHVNEKGTYPNLYSIACFGAAGATAGSCITLLACPFELTKLSAQVSVLLSDQQKLKEANCRATNGHQVAASYQNKGTFKTMRNIIRHRGALGLYTGFNLHLLRDTLGTAIYFMVYESGKQLGTTFGGDHPTTNKLSVVISGGLCGIVSWAMIYPIDSAKSIYQRNSLLYSKGQQVEPPPKIEFFKRHMYRGLGVSMGRSCAVNAIFFSAFEFMKKHVSSLDDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRQ2</accession>
    <name>E3QRQ2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08819</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697371">
        <property type="protein sequence ID" value="EFQ33540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097560.1">
        <property type="nucleotide sequence ID" value="XM_008099369.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRQ2"/>
    <dbReference type="GeneID" id="24414184"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08819"/>
    <dbReference type="eggNOG" id="ENOG502S7GF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038380_1_0_1"/>
    <dbReference type="OrthoDB" id="5398515at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="70"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="104"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="404"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ33540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="434" mass="47559" checksum="C6E0683D4EF6B87C" modified="2011-01-11" version="1">MATTFAASTPSPPPTIRTPPTPKHGWSDNWEPYSPRKSARISSRRAANRTPSPQPPSHRTPSRSTRKSVAPSIAAAAAIMSPASTPQKKRQPAQDSVRRAPGFLSAASSSHAAALLGSDSMDRPSNSTSVTRRSGMLPTPAKTPKKAPSEKQTAQIKSVARNLFPTDDEALATSKRKRTPKKYSGNSLESFTATEVEQQIEIFTDSQERIPEPDKSIDNPFYGDSAAVDREPPRRRSKRKVAVPGEAAQPVDEALQREDGMVYVFRGKKIFRKFAEPEPEDEEDDEESSSGESRIRKPLTRSSIKPRLLFPVASKSSAIGSTIEEEEAVTDIEDHHLEEHEEEEVGSSETPAGTQNECPPTPQAPKFGLTVATPPDTRRTTRSGLKSEEATPIKRKGRQSPFDDWPRVKSRHESSSSKRAGDDLAVPTTKRARN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3QS16</accession>
    <name>E3QS16_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Eukaryotic aspartyl protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_08583</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase A1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697372">
        <property type="protein sequence ID" value="EFQ33654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097674.1">
        <property type="nucleotide sequence ID" value="XM_008099483.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QS16"/>
    <dbReference type="STRING" id="645133.E3QS16"/>
    <dbReference type="MEROPS" id="A01.017"/>
    <dbReference type="GeneID" id="24413948"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08583"/>
    <dbReference type="eggNOG" id="KOG1339">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013253_0_1_1"/>
    <dbReference type="OrthoDB" id="2747330at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06097">
        <property type="entry name" value="Aspergillopepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000024">
        <property type="entry name" value="Endothiapepsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000026">
        <property type="entry name" value="Endothiapepsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034163">
        <property type="entry name" value="Aspergillopepsin-like_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF2">
        <property type="entry name" value="ASPERGILLOPEPSIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6 9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180740" evidence="7">
        <location>
            <begin position="23"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="8">
        <location>
            <begin position="97"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ33654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="410" mass="42980" checksum="E704330E58FEB8C5" modified="2011-01-11" version="1">MTASSFVSALAAGLALASTAAALPAATQQESNFSVEQVPNTRYVRSGPLALAKAYRKYKIPLPQDLASAVSNITNARLGQRDTGSETANPEPSDSEYLCPVKIGTPAQTLNLDFDTGSSDLWVFYSSTPSSERDGQTVYNPSKSRTASLLSGESWSISYGDGSSSSGIVYSDVVSVGGLSVSGQAVEVAQTVSDEFSQDSDNDGLLGLGFSSINTVSPNQQTTFFDTATPQLSSPVFTADLKHNKAGKYNFGYIDNSAYTGSITYTSVDNSQGFWGFTSSGYQVGSSSFTKKSYEGIADTGTTLLLLPDSIVKAYYKQISGAKYDSSQGGYVFPCAATPPSFTFGVGSARITVPGSYMNFEAVSSSSCYGGIQSNSDIGFTIFGDIALKAAFVVFDGGNTQLGWASKTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QT85</accession>
    <name>E3QT85_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_09217</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697376">
        <property type="protein sequence ID" value="EFQ34073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098093.1">
        <property type="nucleotide sequence ID" value="XM_008099902.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QT85"/>
    <dbReference type="GeneID" id="24414582"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09217"/>
    <dbReference type="eggNOG" id="ENOG502R1EE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_567418_0_0_1"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ34073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="493" mass="56075" checksum="D3359CEBC26AA70D" modified="2011-01-11" version="1">MCIKHVQFYECPSEPIKNPPGHNPPKKHRVRANILCSQVFPCPAPQWEKRVSRYGFMCPACSGESPAVPRDTPVSDEWKRDELQDEAWVQSYLSEYCHAVLLWIRSQWGAGDDDAAVAAEAAESWLSAFFMERRCKENDHRVGECRCEANGPLAYFYNPTTAARRYLTDLAADKLEGDPRVRSPEMQVVLANRHMALSAVCRERNLYFKDGISRQPFFSERNIGRRRRILQKSLDDAAKTADRLMLENAENAEGAVAAGAGGGRWTAAHTLETARVSRRASLVRFMGEVLLYDNGISNGRFSLAVSWLAHVIQVAAWRTASRVEGLEKLARMASEMDQASMPSQPFTRLVQLVQKYYFDRRAEWKAQVMKYKARRSVFDRVTAPIDPWRELEDEEGWRSCRICKGGFYVSPANMTEQSHPGVDMGDYGEPAWQMKDCWCIFGRRCLFQWITDTSTAAKEPECPGCGMQFPFREYQLVEASTGYSIRNDPPGDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTW6</accession>
    <name>E3QTW6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CHRD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09422</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697378">
        <property type="protein sequence ID" value="EFQ34278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098298.1">
        <property type="nucleotide sequence ID" value="XM_008100107.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTW6"/>
    <dbReference type="GeneID" id="24414787"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09422"/>
    <dbReference type="eggNOG" id="ENOG502S4XH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063722_0_0_1"/>
    <dbReference type="OrthoDB" id="3554264at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010895">
        <property type="entry name" value="CHRD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07452">
        <property type="entry name" value="CHRD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00754">
        <property type="entry name" value="CHRD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHRD" evidence="1">
        <location>
            <begin position="51"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="210" mass="21868" checksum="B1AD8C64E2BE014B" modified="2011-01-11" version="1">MKSAYAPLVLAAVAAASPIKLIEDVAHSIGLYNKGGSSGYQGASGPFSFTSTYDVIATPDQVVDNNNTFTGGLAGAVGYYSYGINSYENVICYNITLVGFRGEYQSPAVSATHIHQAQKGLAGPPRIAFPNPVPVEGAQNVRRSIGCVSGPFRTGVNATGVDTGTGFTVRQIEENPSDFFTDVHSSLAVPGAVRGQLSDGVNADCEDKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUJ4</accession>
    <name>E3QUJ4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09676</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697381">
        <property type="protein sequence ID" value="EFQ34532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098552.1">
        <property type="nucleotide sequence ID" value="XM_008100361.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUJ4"/>
    <dbReference type="STRING" id="645133.E3QUJ4"/>
    <dbReference type="GeneID" id="24415041"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09676"/>
    <dbReference type="eggNOG" id="ENOG502RQ6Q">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058465_0_0_1"/>
    <dbReference type="OrthoDB" id="4831096at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="370" mass="41896" checksum="8BF0E54384177E6E" modified="2011-01-11" version="1">MANRRDRGTALITPEERVRRVQEAKNNIRKTATYTPALLGRIQSRIDANAFRRCISDNTIYQSLCNSLKDKNIPERERRPDLVDFLALEAIVPVNYDGEYNRVLKDLFVRCHTEAWVVEAVLQANHEWFQDAIGEARRYIKTLVTRIDSQLLEIILEDIETSFWREETREHPLYHRVIDKVAKGQTLTQRDVITAVAINGGKYPTEIFRHLVIKQNSNMLNWGSNISAQNALYDDEDFQGVRADTTIYSETMVNLESFANAMQNKKNSHEVRKKIREMKELMKDDVGVLRHTQGGRVQKVAGGSNGNGDIHPRCNSEASNSPGLCVNQEPGDCGQYFDGMQGDMGGEGNHGGASIKREEFGADGFFTQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QV70</accession>
    <name>E3QV70_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glycoside hydrolase 131 catalytic N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09904</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697383">
        <property type="protein sequence ID" value="EFQ34760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098780.1">
        <property type="nucleotide sequence ID" value="XM_008100589.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QV70"/>
    <dbReference type="STRING" id="645133.E3QV70"/>
    <dbReference type="GeneID" id="24415269"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09904"/>
    <dbReference type="eggNOG" id="ENOG502SB15">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1844931_0_0_1"/>
    <dbReference type="OrthoDB" id="5283326at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041524">
        <property type="entry name" value="GH131_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18271">
        <property type="entry name" value="GH131_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase 131 catalytic N-terminal" evidence="1">
        <location>
            <begin position="12"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="139" mass="15804" checksum="1B2D44B46D3D2C41" modified="2011-01-11" version="1">MSFLQLRCTICFFHFSVQRDATKPLNYTHEYQIVNLELKDFSFHQFGECTGVDNGNEIAIFGNFKATLPEKIFPSTPSVDGQFENFVMKLDFNAKHVPDKISVGDASQPEGIQQALIFGSIFMRDSTGWYGHLSMNEVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QV76</accession>
    <name>E3QV76_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyanovirin-N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09910</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697383">
        <property type="protein sequence ID" value="EFQ34766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098786.1">
        <property type="nucleotide sequence ID" value="XM_008100595.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QV76"/>
    <dbReference type="GeneID" id="24415275"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09910"/>
    <dbReference type="eggNOG" id="ENOG502T4HE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1272193_0_0_1"/>
    <dbReference type="OrthoDB" id="4809471at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.60.10">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036673">
        <property type="entry name" value="Cyanovirin-N_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179976" description="Cyanovirin-N domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="188" mass="21297" checksum="355E6AAE5959A67F" modified="2011-01-11" version="1">MRFQLLILLAMAVAALASRGPPPVRPIRESKDPGLCIKRLETYPRRARPWVDILGGHCLQSRTYKVKYGPHKGSFFFETCCKDKNDNYAEPTFVNVDECVVFDPAKGQLSWNNLNSKKIRDHCSKCRLEQVDKPEQGQTAGPYLSCECAKDDKTTVKAKIFLGTDGRSAKEPKDSFWVNEKGRLLCKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVA5</accession>
    <name>E3QVA5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Calpain family cysteine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_09937</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C2 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697384">
        <property type="protein sequence ID" value="EFQ34793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098813.1">
        <property type="nucleotide sequence ID" value="XM_008100622.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVA5"/>
    <dbReference type="STRING" id="645133.E3QVA5"/>
    <dbReference type="GeneID" id="24415302"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09937"/>
    <dbReference type="eggNOG" id="KOG0045">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006072_1_1_1"/>
    <dbReference type="OrthoDB" id="424753at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004198">
        <property type="term" value="F:calcium-dependent cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00044">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022684">
        <property type="entry name" value="Calpain_cysteine_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000169">
        <property type="entry name" value="Pept_cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001300">
        <property type="entry name" value="Peptidase_C2_calpain_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183">
        <property type="entry name" value="CALPAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183:SF425">
        <property type="entry name" value="CALPAIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00648">
        <property type="entry name" value="Peptidase_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00230">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50203">
        <property type="entry name" value="CALPAIN_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00139">
        <property type="entry name" value="THIOL_PROTEASE_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Calpain catalytic" evidence="5">
        <location>
            <begin position="225"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="187"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="695"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="734"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="915"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="187"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="702"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="739"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="807"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="851"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="active site" evidence="2 3">
        <location>
            <position position="253"/>
        </location>
    </feature>
    <feature type="active site" evidence="2 3">
        <location>
            <position position="431"/>
        </location>
    </feature>
    <feature type="active site" evidence="2 3">
        <location>
            <position position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR622684-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ34793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="935" mass="103523" checksum="814D698D39718688" modified="2011-01-11" version="1">MATYGDPPPAVVPAVPSGKRSKKAPQEILSDFWNKFHSKHPGKVTSIFPRSLYASLLPDFQPRGASSNRNAQESYESAARECREKVKRIVRECDRTNEKFTDADFDIERDPYNNCLNGLVRDFDFGPGGGGGGAADDGPNVSSWDVKNSFDTLAAAQVLGPNSTIPIDPAVVSRFLGSSDDSWNPFASARSGSGARAGLRSGPVKAPKRQGVRGGEYYSPGSIHRLDWIFESPQFTVNGYSSSDIKQGANGDCWWLAAVATIAHRKDLMQKVCVARDEECGVYGFVFQRDGEWISTVIDDNLYLKESDFDYYGDVYDASGKKARLHRKRNQTGSDALYFARCEDQNETWLPLLEKAYAKVHGDYEAISGGWPGEAVEDMTGGVTSTIATNRVLRKDRLWKELVNTDGEFVFALAAMGTGWDWQKSGLALGHAYSILQSREEVDEDGKKVRLVQIRNPWGERSDGGVGEWNGPWSDGSKEWTPYWLKRLNHTFGDDGVFWMSYEDMLSTFMYIHRTRLFDEKWTVVQQWTSANISWVTGYLQTKFVIEVKKSGMIVIVLTQLDDRYFHGFEGQYWFELHFVLQKAIPEAAGDKSKEGENTKNAPEPEQICRVRPVHKWENRSVSCEVDLEPGVYEVLPKVAASRHYNGDAAKPVEEVVKEYAERNPQKLRQVGLQYDIAHSKGGVRDEDGLIEKKKLEAKQKKESKKAKKKKKQKKALGVAAKALEESAKVVAELANEGNKTEESKSAVKTETKKEAGQEKEKEKDGDWTEVKESDKDSTGSSQKSVPTDDKPAGLTGSKPSDGPVPEPKKEDEKKAEEKTEEKQDEGREDAPAVKEAGTAEASVVPSPATTEEEVPVEAPVEEEEDSESDSDSDTESIVEDDGEELTGAPWNAVCVLGLRVYSQDSDVAIKLVKPSDEEEAASLTVDGEAAGATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVD0</accession>
    <name>E3QVD0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11 12">Endo-1,4-beta-xylanase</fullName>
            <ecNumber evidence="4 11 12">3.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">GLRG_09962</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11 12">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-xylosidic linkages in xylans.</text>
            <dbReference type="EC" id="3.2.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11 12">Glycan degradation; xylan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11 12">Belongs to the glycosyl hydrolase 11 (cellulase G) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.8" evidence="4 11 12"/>
    <dbReference type="EMBL" id="GG697384">
        <property type="protein sequence ID" value="EFQ34818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098838.1">
        <property type="nucleotide sequence ID" value="XM_008100647.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVD0"/>
    <dbReference type="GeneID" id="24415327"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09962"/>
    <dbReference type="eggNOG" id="ENOG502S2KQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052631_0_0_1"/>
    <dbReference type="OrthoDB" id="2115822at2759"/>
    <dbReference type="UniPathway" id="UPA00114"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031176">
        <property type="term" value="F:endo-1,4-beta-xylanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013319">
        <property type="entry name" value="GH11/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033123">
        <property type="entry name" value="GH11_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001137">
        <property type="entry name" value="Glyco_hydro_11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46828:SF4">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46828">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00457">
        <property type="entry name" value="Glyco_hydro_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00911">
        <property type="entry name" value="GLHYDRLASE11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51761">
        <property type="entry name" value="GH11_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11 12" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9 11 12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 11 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 11 12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0732">Signal</keyword>
    <keyword evidence="5 11 12" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003181005" description="Endo-1,4-beta-xylanase" evidence="13">
        <location>
            <begin position="22"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="GH11" evidence="14">
        <location>
            <begin position="31"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="11">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EFQ34818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="224" mass="24157" checksum="24A81FF0D55FB62E" modified="2011-01-11" version="1">MVSLTFTYLAFAASLITSVFASPVANLDTPDFELGPANLARRQDYTQNYKTGGKVNFTPNKKGFSVSFSGAQDFVVGKGWNTGSKNRTVEFSGQTKASAGTVLVSLYGWTTDPLVEYYVQEYSNNGKGAAQGQKVGSLKSDGSEYDIFKHTQVNQPSIEGTATFTQFISARKDTRSEGGTITFANHVAAWDKVGLKLGKMNYQTIATEGWGNAGGNSKYTIKSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWE2</accession>
    <name>E3QWE2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Myb-like DNA-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_10324</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697389">
        <property type="protein sequence ID" value="EFQ35180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099200.1">
        <property type="nucleotide sequence ID" value="XM_008101009.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWE2"/>
    <dbReference type="STRING" id="645133.E3QWE2"/>
    <dbReference type="GeneID" id="24415689"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10324"/>
    <dbReference type="eggNOG" id="ENOG502QRT9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008791_0_0_1"/>
    <dbReference type="OrthoDB" id="3366990at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003691">
        <property type="term" value="F:double-stranded telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010833">
        <property type="term" value="P:telomere maintenance via telomere lengthening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11660">
        <property type="entry name" value="SANT_TRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000137">
        <property type="entry name" value="MYB DNA binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013867">
        <property type="entry name" value="Telomere_rpt-bd_fac_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052833">
        <property type="entry name" value="Telomeric_DNA-bd_trans-reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47807">
        <property type="entry name" value="PROTEIN TBF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47807:SF1">
        <property type="entry name" value="PROTEIN TBF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08558">
        <property type="entry name" value="TRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb-like" evidence="5">
        <location>
            <begin position="584"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="6">
        <location>
            <begin position="589"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="420"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="522"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="572"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="669"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="704"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="437"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="522"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="533"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="573"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="675"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="721"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="810"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="843"/>
            <end position="855"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ35180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="883" mass="95782" checksum="1FA3923EA55BCACB" modified="2011-01-11" version="1">MLMEGAEEAIAESAQAAKAEAHSPTGPEMKQESPTVATDLGETPPFPLKRPRDASAEDPDAEPKRLKVDDEAPSLDLNFDMDAMIQGVMMDINNEMGKVDGLDSVSDVDMTADALASVSQDTNHSVEPHPIILSEPLALMRRTTTSCLSNFAMQLLVIMSQHVYDDIYRQLQDKDTELSKSYSTLKTIFRQTRSIYSTTDLILDPAVLDLTAPDNLTDIQVANLASFCCELFAFDGHHDLASQQLLALKDKFFPVFLSGDESVSHDISELFVAVKTQLVIESVTTADQSAPVDQLIAEAFSSDLEDKLRARHDGTELTPEEKAMVTAVEERKAGLIAYASGLPDTVLLKIGYPEEDLFRLLNTYLRQKLHSLSGLASRHGIELPQILTDSDLDASMPPDLDDLGISSLLEATDGLVAQYLPSDPIDGLPSEQPPVPTTETSAPPAEPTTSAPESTPSAAPAPNGTTTETHDSTSDILALVAQSTQEYVRTTLNNLSPAPYQPTVPTPTGVVPATQTTYLSHLQQTQQQSPYYGYPPPVEQPPQPASHDSNEKLPPSQSLPSAVLYDRARQAALSKTNNQQRREGTTSTRRPWTQEEEKALMTGLDMVQGPHWSQILSLFGAEGTLSNILKDRTQVQLKDKARNLKLFFLKTNSEMPYYLQAVTGELKTRAPTQAARKEAEERARMNSEEEQARVQGIMTLAGGLQHPQQNRPSVAPPTAPSTPLQSAAQMSSHHMAAHATTPTHAAASAPPATPAAATPTHARVPHASSPYAATAAQLSHTPHHALSQAQAQVQPQTPSHSHIQQHHSHPGTPQPQHQQQQPQQPQQEHVQPQVSQAAEPAPQYSTDSSAPVYSQENEDLKEAALMQSLRELEAYSGSSASLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWP6</accession>
    <name>E3QWP6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Thioredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_10428</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioredoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697390">
        <property type="protein sequence ID" value="EFQ35284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099304.1">
        <property type="nucleotide sequence ID" value="XM_008101113.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWP6"/>
    <dbReference type="STRING" id="645133.E3QWP6"/>
    <dbReference type="GeneID" id="24415793"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10428"/>
    <dbReference type="eggNOG" id="KOG0908">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072377_0_0_1"/>
    <dbReference type="OrthoDB" id="2121326at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000245">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.470">
        <property type="entry name" value="PITH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010400">
        <property type="entry name" value="PITH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037047">
        <property type="entry name" value="PITH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46115">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06201">
        <property type="entry name" value="PITH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51532">
        <property type="entry name" value="PITH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="PITH" evidence="5">
        <location>
            <begin position="130"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="113"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ35284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="322" mass="35289" checksum="C9AF021D090780B7" modified="2011-01-11" version="1">MSTVHIKSPTEFQTLLSSSRIVVADFYADWCGPCKAIAPLYEQLSSSLSRKNVVTFVKIDVEAQKEIASAYNITSLPTFMIFREGKTLEKVQGADPRKLQEVVKKLAKEVSEGGSGSGEASGSSGGGSWRGVELPRGYSDITDQVEARGCELLNADEDFGPVRVLFDMSKPSALAKKEGVKDWVESGADDQLLLFMPFQAMLKLHTLQLTSLPPADDDEAPMRPGTIHLYTNKPHNLDFSEADDTPPTQAIELTEKDWNADGTANIGLRFVKFQNITSLIIYVTKGDGEGEKVRLDRVRLIGESGEKREMGKLEKIGDEAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWV8</accession>
    <name>E3QWV8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Glycosyl hydrolase family 32</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_10490</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 32 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697391">
        <property type="protein sequence ID" value="EFQ35346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099366.1">
        <property type="nucleotide sequence ID" value="XM_008101175.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWV8"/>
    <dbReference type="STRING" id="645133.E3QWV8"/>
    <dbReference type="GeneID" id="24415855"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10490"/>
    <dbReference type="eggNOG" id="KOG0228">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013784_3_0_1"/>
    <dbReference type="OrthoDB" id="202537at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004575">
        <property type="term" value="F:sucrose alpha-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005987">
        <property type="term" value="P:sucrose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18621">
        <property type="entry name" value="GH32_XdINV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.560">
        <property type="entry name" value="Exo-inulinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001362">
        <property type="entry name" value="Glyco_hydro_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013189">
        <property type="entry name" value="Glyco_hydro_32_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013148">
        <property type="entry name" value="Glyco_hydro_32_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42800">
        <property type="entry name" value="EXOINULINASE INUD (AFU_ORTHOLOGUE AFUA_5G00480)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42800:SF3">
        <property type="entry name" value="GLYCOSYL HYDROLASE FAMILY 32 N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08244">
        <property type="entry name" value="Glyco_hydro_32C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00251">
        <property type="entry name" value="Glyco_hydro_32N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00640">
        <property type="entry name" value="Glyco_32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180895" description="Glycosyl hydrolase family 32" evidence="5">
        <location>
            <begin position="26"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 32 N-terminal" evidence="6">
        <location>
            <begin position="53"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 32 C-terminal" evidence="7">
        <location>
            <begin position="460"/>
            <end position="624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ35346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="659" mass="71918" checksum="6570CEF7B51B8C95" modified="2011-01-11" version="1">MALLKGGPVFTAIASLAAIAVPVAADVPATITPESFATTGNSSLFTRWRPRSHFIAPHSWMNDPCGAVYDPATSTYHLHYQFHPNHVNWGNISWGHAVSKDLFHWTDVGDWANDSSVSLAADKYPAAPLSVFTGTTMPVNVEGVNDGTLLTFSTGIQALPTNWKKPYIPGTEVQALYTSTDGGLTWNEISTVLSSPPEGWNVTGWRDPHFFPSEKLDDLLQVSEPHYYMVLGSGLKSDDVPATFPNAARPGFIGPRIPLYSAPASNLTQWTFLGALWEPAANTSLGHPDVTGSYGYNFEVSSFFDLPVGETGEKAWFVTMGAEGGNTTQHWKESWSLWNRGDVARRDNGSVEFTPNSGAALDWGLTYAQATWADSRNNNRRIVWGWVNEDMLSDYQLETATKFGYQGAINLPTELYVQETKGVQNCGTQQDGTYCIESWDGATAQTLGIRPLPDVMEILRQGAEVQEFQVGGLTDAAKSVSANIGSSYELTATLSSCNGPAGITIGQSPDNAEYTTIVFDPAISQISVVREHSSLLPNFNNATIVGHFEPYEIHNASSNTTATEDINFHVVLDGSLLEIWVNERFALTARIYPSRNDSTGLGFFAGDAAAPAGGKATWKDIKAWVGLAKAWPERPEDTSVPLVWDTPEETNNYQWWDGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWY7</accession>
    <name>E3QWY7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_10519</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697392">
        <property type="protein sequence ID" value="EFQ35375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099395.1">
        <property type="nucleotide sequence ID" value="XM_008101204.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWY7"/>
    <dbReference type="STRING" id="645133.E3QWY7"/>
    <dbReference type="GeneID" id="24415884"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10519"/>
    <dbReference type="eggNOG" id="KOG1721">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008344_0_0_1"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000343">
        <property type="entry name" value="C2H2 transcription factor (AmdX)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000576">
        <property type="entry name" value="C2H2 transcription factor (AmdX)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF13">
        <property type="entry name" value="RESPIRATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="68"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="96"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="117"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="794"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="946"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="13"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="799"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="956"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="997"/>
            <end position="1006"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ35375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1185" mass="128561" checksum="BE32020F0C3E8CF5" modified="2011-01-11" version="1">MAMNDTEVKAEKNTSMTNSSSTPAAPAAASAANSTAPATEDSAASTITVNTKTPANFPPPKTDKPRPHVCATCQRSFARLEHLKRHERSHTKEKPFECPECTRCFARRDLLLRHQQKLHQTTTPSSRPRNRRESASSAAPGARARKNSVAGPNAAAAANAAAASMRPRANTISHVDGSAMQMIAAANAQAARGMPPGTHSRHPSLAGLPVHNLDFGGMSAAMGHRGMSHGLPKLETHTINHMDFSGLRTAPPMAVFNPDFDFEGLLFGPGSTINPNALHYNDSPQSMAMDQPSPFQHGLAGDLSTTQLDDSFDWLTGFEHQMSFQGADNAVDGSSPSAISTTSQSGISDVMVDGSNHPVPAGTSSMWQPAVMGPPQVPNPFAMDLNGSVFPDLLNGAPVSPQPAAQKMNDAYFSTPPPSLSSLSPSMISGLNTQNLNHAALSFNAGPETPSSMNGGNHGVSPVSTITESTRGAIVGALSQCSPFGGRRYSFATPSSPLSPGFQNTANSVPDHVKNLPSTQDLQRYVGAYLRYFHPHLPFLHIPTLTFEMPPSAANRPNTVGGSGCLVLSMSAIGALYEMDHVQSRELFEMAKKMIQLYLEERRKADVRKADLRRTPASEPSAHSQESSVHTPVWLVQAMLLNVVYGHNCGDKTASDIASTHCAALVSLAQAADLLRPIRVESNDAPHDTHMHDDATWSSLQPDSDEQVEWLRWRTMEERKRTLYVVFVLSSLLVAAYNHTPALTNSEILLDLPCDEDFFAAESSTAFAAKGGVRAANHNRMTFHEALGDLLRSNEKQQKQQQQQQLAFGNGHQASAQGGGGSSLDELHKNDLKPSTFGCLILINALHNYIWETRQRHHNKVWTNEETEKMHRHIEPALKAWQAAWASNPNHSLERPNPFGLGPLSADAIPLLDLAYVRLFVNLARSKEKFWQRDWDAMAEELSRGTEVVQHAEHSPASNAESTGTENSDNSVSTSVFAESPATQSSSPEFPSGKFPSHSQAAPSQSTRRREKHLRKAAFYAADSLAMSDKLGVTFADFTSRELPLQSAMCAFDCAQVLAEWVATLQDRVGQYLGILGQDDVDLSQVPAIMMLEEEDVKLLGKVQEVLASAELKMNFELVQGNVAGVDTRMHMDDHAGYAAKILRITAYMLDKAAVWPVTHLMARCLETHATHMRARADKSVVAHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QY77</accession>
    <name>E3QY77_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10924</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697401">
        <property type="protein sequence ID" value="EFQ35815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099835.1">
        <property type="nucleotide sequence ID" value="XM_008101644.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QY77"/>
    <dbReference type="STRING" id="645133.E3QY77"/>
    <dbReference type="GeneID" id="24416289"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10924"/>
    <dbReference type="eggNOG" id="ENOG502SK2K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002639_6_3_1"/>
    <dbReference type="OrthoDB" id="47007at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF10">
        <property type="entry name" value="TOL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="205"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="672" mass="75323" checksum="E649BE774FC4775B" modified="2011-01-11" version="1">MSLCQVCSKLHIEQLDGTDVRFHSNLKALQQSALARCPFCSLCYTRVMEDTSRSITGALLNDEVPEGYEKETFFPSVWLHGEVRQANRGVGKQLPGCAIWISSGRLHPDGGQGETNHPGMPFASRLSVFASTSTPAASKYIERFSTADHDPDLHIHLAGWRMRRCKASHKLCKPRSSEMPTRVIAVGQASQKPRLIVTNGLQEPYLALSYCWGPGRDTFNLTHKTKDELFGGVAEGKLTKTHQESIHFARSLGIEYVWIDALCIIQGDADDWTFESQRMAQVYGNAVLTIIAGRSNDARDGFLTNRLDQKVPPCALPLAPNTKDTVNVCLPRSHAYGPVSTRGWCFQEEKLSTRAVILGKEQIIYQCRSETSWEDGQVNFADLKPTFLIPGFSTDAARSAADKETTLDMWYEFVDTYMMRDLSNPHDIFAAIASIAGLAQDVLGSRYLAGLWEDDLVQGLSWKPRHQVNGFFKGPLTRPKPTPFAPAPVVRAPSWSWASVQGPVRRFYKLKESKMFHDSDYVKIRPRLGEKRWAATNDCGVAALHMPHCELQILARTAKAVLVKTGVAEWFAADRSRKRWLPYSKMRSYAVLLTSTERNPDAASSDDGVVAVGAFDVAEEAEQFEEVWCLPLIEKEGLMVVQSETKWKRVGWFVLRDESWFEGRPEVEVDLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYT2</accession>
    <name>E3QYT2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_11164</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697406">
        <property type="protein sequence ID" value="EFQ36020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100040.1">
        <property type="nucleotide sequence ID" value="XM_008101849.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYT2"/>
    <dbReference type="STRING" id="645133.E3QYT2"/>
    <dbReference type="GeneID" id="24416529"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11164"/>
    <dbReference type="eggNOG" id="ENOG502SKIK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057547_4_1_1"/>
    <dbReference type="OrthoDB" id="4841081at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ36020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="268" mass="29860" checksum="0DC83750C8F79CCC" modified="2011-01-11" version="1">MSSCTPTYLPSPNWDIPADSNIVVLGRLIKDPKNPQSKVPRSSDDPIPPLKIYEGEKTDWQTTVERTRSGSIGLWAKCLQFVGGQLSFGQLKSAMEDHRFASLETKYFLPDDDYLAQALEDAGVQAYFHVNNHRKPVYMITGIKIARGASVSAESSTERLVQAEVKADVTSVGAPVEVGPEISWESLKKRGVSYGGSTDYIFAYQLMRMKPKKGGRESKNQSYVKGALYGKREEGDATEVKLRDVFEIEEEASHGFPDTWEQVDEDEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYU0</accession>
    <name>E3QYU0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Guanine nucleotide exchange factor Vps9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_11171</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697407">
        <property type="protein sequence ID" value="EFQ36027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100047.1">
        <property type="nucleotide sequence ID" value="XM_008101856.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYU0"/>
    <dbReference type="STRING" id="645133.E3QYU0"/>
    <dbReference type="GeneID" id="24416536"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="456"/>
            <end position="595"/>
        </location>
    </feature>
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        <location>
            <begin position="762"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="331"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="422"/>
            <end position="457"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="627"/>
            <end position="676"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="689"/>
            <end position="744"/>
        </location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <begin position="24"/>
            <end position="33"/>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <begin position="90"/>
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            <begin position="111"/>
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        </location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
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            <begin position="151"/>
            <end position="161"/>
        </location>
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            <begin position="179"/>
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    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="805" mass="88050" checksum="B72416888E00EDA6" modified="2011-01-11" version="1">MSFTDPTNHSSSLSGDTKHDSDTVPVTGTQNAGSKAETEPPELGNQQGPQSKAVLSAKAAGKQQATGDLIDFGDDDLEPTPETKPAASLDSKSALGSSQTAFAPALESTLEPMTSSIATLKPTSPLPAETTTQYLTIESTTYVDPTPPTPRASQPPSRTPSNATKRRSSSETSPTRSDAGYDERRYASEDEQENGSRSEIQSIMEQFTGDGRGPGAEEVMSPRLEIASPMLGSPGIHHPPRKSSLDPLVPSLSHQVQELQGLRIHSASPVSMLSRERVSDDQGPPVPPKDGPPATPSRSHDDRHISTDSQMSPGLPIHRPPPPEPEPEPALPFDFHRFLEQLRNKKADPVARYLKSFLSEFGKRQWMVHEQVKIISDFLAFIANKMAQCEVWRDVSDAEFDNAREGMEKLVMNRLYTQTFSPAIPPPQPIPGAKPKRRGGERPMGPGRRGQHQEDVERDDILTQKINIYAWLREEHLDIPPAGDSGTRFLKLAQQELLKIKSYRAPRDKIICVLNCCKVIFGLLKHSKSDSSADSFMPLLIYVVLQANPEHLVSNVQYILRFRNQEKLGGEAGYYLSSLMGAIQFIENMDRTTLTITDEEFEKNVEAAVSAIAERHRLDSPAVAQEPVFSEKMGFQQGESSGRPSLDMIGESSIPRRSMSSNEGSRDVEDQAPITGLLRSIQKPLSTIGRMFSDEPSPAPPPVPSSASRPPGPPERLSPRLSMERPPDGQQPASRPHLSAEEAAARQASAEVAEAQRLSRAEHNNVVETLAGMFPDLDRDIISDVVYQKQGRVGQAVDACLALSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZ02</accession>
    <name>E3QZ02_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11234</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EFQ36090.1"/>
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        <property type="nucleotide sequence ID" value="XM_008101919.1"/>
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    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="107" mass="12014" checksum="B79106C0FBCCEDA7" modified="2011-01-11" version="1">MSISDSHLQHQGSYPPRNVIVSVPLADYLTTGGEAYHRSYLAALIAIASSSGGPDWRNLLLALLYTIVLTVIFSRRGLAMWSQTALYRFFNAWWFGWIAKPAQRRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZJ0</accession>
    <name>E3QZJ0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aromatic prenyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11423</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697416">
        <property type="protein sequence ID" value="EFQ36278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008102107.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZJ0"/>
    <dbReference type="STRING" id="645133.E3QZJ0"/>
    <dbReference type="GeneID" id="24416787"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11423"/>
    <dbReference type="eggNOG" id="ENOG502SIKB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037431_4_1_1"/>
    <dbReference type="OrthoDB" id="5392033at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009820">
        <property type="term" value="P:alkaloid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13929">
        <property type="entry name" value="PT-DMATS_CymD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033964">
        <property type="entry name" value="ABBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017795">
        <property type="entry name" value="ABBA_NscD-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03429">
        <property type="entry name" value="arom_pren_DMATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40627:SF5">
        <property type="entry name" value="INDOLE PRENYLTRANSFERASE TDIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40627">
        <property type="entry name" value="INDOLE PRENYLTRANSFERASE TDIB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11991">
        <property type="entry name" value="Trp_DMAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00036">
        <property type="entry name" value="Aromatic_Prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="413" mass="45062" checksum="91CA1EAEFC7B0A77" modified="2011-01-11" version="1">MEIYRLTVVNDANGSITEKSIYKDAVASSPSSKGSPLFSSWLPLIHNSLTSLLRWTGTYPAEVQESHLAFVRDVVVPRLKPPAAADRLYYIGTHSHGIYEASLAFATHKPARVRFTVQPLVDPSPAQGGDLLGQKALRNTLEGMASACGADRAWLDAFLDSVFLTAEEELTLVGKRGMDAANGDAGAAGGPLRQNGFVAFDLEADMDENEKAVTVMKTYLFPQLKAIATGQKTVNTTDSIVKRLAGGDKDMLAAWELVKTFLITDGGEKINLDFLAIDCLAPCKEPRFKVYVSTRFKSLAAVREAFTLGGLLPSSSADFLSQVWPQLLDMEDIPQAEMEDLEKPLNNPDSHHQGVGFAFSVVPGQAVPQIKMYVPMWQFARDEARIVECYRRVLQTQGTMGDYDINAAIQGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZV3</accession>
    <name>E3QZV3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_11536</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the beta-lactamase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697421">
        <property type="protein sequence ID" value="EFQ36391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100411.1">
        <property type="nucleotide sequence ID" value="XM_008102220.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZV3"/>
    <dbReference type="STRING" id="645133.E3QZV3"/>
    <dbReference type="GeneID" id="24416900"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11536"/>
    <dbReference type="eggNOG" id="ENOG502S3SB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_778465_0_0_1"/>
    <dbReference type="OrthoDB" id="10250282at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051478">
        <property type="entry name" value="Beta-lactamase-like_AB/R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22935:SF95">
        <property type="entry name" value="BETA-LACTAMASE-LIKE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22935">
        <property type="entry name" value="PENICILLIN-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="2">
        <location>
            <begin position="68"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ36391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="356" mass="39241" checksum="4D8AA0C748B2646A" modified="2011-01-11" version="1">MHPVAILENIPNYEYHAHVITLFSLFKGTRDNLYPSLGTAIPSLKTPSDLKAVRETIEEIQEGLVNHNRNTAKVEIHTTYRGGSITKPFTTLVALQNHCIKKTDSVIEYLLQLKTEAVQNEGQFNFIPLDNITIWDLTSHLSGLGGDNLLTGLNNTPPLIRPNTTLVYFSIGLEILSPVVEATNNKTYEYILVKTFLSEPTWGGDLDIYASAGGIYTNKRDMLTFGAAILSSDIGINVGFWLKPHVFNFSRGYSISAPWEIWASFTLLESGVPVSFYIKFGDLGLSTNVLIIVPDYDLVTFIHATGAQSAATFSLPTQDISLVMKVLILTLEKASKESAHAAVAGTFTDQKTNFVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3R039</accession>
    <name>E3R039_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PD-(D/E)XK nuclease-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_11622</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697426">
        <property type="protein sequence ID" value="EFQ36477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100497.1">
        <property type="nucleotide sequence ID" value="XM_008102306.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R039"/>
    <dbReference type="STRING" id="645133.E3R039"/>
    <dbReference type="GeneID" id="24416986"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11622"/>
    <dbReference type="eggNOG" id="ENOG502SSXD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027219_0_0_1"/>
    <dbReference type="OrthoDB" id="4161186at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046797">
        <property type="entry name" value="PDDEXK_12"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20516">
        <property type="entry name" value="PDDEXK_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PD-(D/E)XK nuclease-like" evidence="2">
        <location>
            <begin position="160"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ36477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="434" mass="48433" checksum="4F90645BA19EB542" modified="2011-01-11" version="1">MVPGDTTTSPKKHKGASSARDSIDGNDTELFFPRDVDLDQTPTRHSNAALYTSFRPRASRSASRSPTKSRSTSGFSDRQSNASSSARRKFIELPLKEEGIVKRELSDALTDQDAPAAIRSMLQKIRSLERCRGVLCQSRRDDPSFVPLMRDADLDDAVYAVSKDHPASRLTAANAQEIVADARRCFLMDHDESVWNADVHNMLLRMVLRPATGRQARLGEFSLCTTAPIIKDYLPEGEAEKKVDFCMYINPSADPDVSLQSKIVALRRALPETSLNHTSYVALCPYPISVSLETKRPGHDLNGAILQIGIWQATHWKMLRRLLGWTAPERLRRQGRASASPEDIDALVNDELAKLGALHGVLIQGHDWSYVATSPESLDGPAKAHSLKTVLWLQKSFGHTSTELGVHQVAAFLEQLNTWSTQVYWPWFKRCFLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0U3</accession>
    <name>E3R0U3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_11879</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697492">
        <property type="protein sequence ID" value="EFQ36731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100751.1">
        <property type="nucleotide sequence ID" value="XM_008102560.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0U3"/>
    <dbReference type="GeneID" id="24417242"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11879"/>
    <dbReference type="eggNOG" id="ENOG502SJSY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046029_0_0_1"/>
    <dbReference type="OrthoDB" id="10061782at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003181065" evidence="1">
        <location>
            <begin position="35"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransferase type 12" evidence="2">
        <location>
            <begin position="63"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ36731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="249" mass="27382" checksum="DA1A2B8C883C6B61" modified="2011-01-11" version="1">MTRRTFGNAIYFPLLLHWIYDTLVLDVYCPLAWGCSKNTLQKHYSRAVSAAALNNATDRPRLLDIGVGTGYWISHAPLAPRSSVLLVDINENPLAESKTRICKAHPTVLVETDKIDVFDLGSAKPVLSPPGGGCGHGDIKFNVTSCMLLLHCLPGTADSKGRALARLSHMLNTDGVLVGATVLGRGVKHNVLGRFIMFWHNLLGIFHNYDDGANDIVEHLKSAFKVVNWRIEGTMLLFEARSPRLQDSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3R164</accession>
    <name>E3R164_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11998</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697660">
        <property type="protein sequence ID" value="EFQ36852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100872.1">
        <property type="nucleotide sequence ID" value="XM_008102681.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R164"/>
    <dbReference type="GeneID" id="24417361"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11998"/>
    <dbReference type="HOGENOM" id="CLU_2793853_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="68" mass="7517" checksum="38230BD0104F178A" modified="2011-01-11" version="1">MGTGTEAGPLDLGHFIPNLRRLGFPTNRLPSRLSRRTCRPLNKAASWAEDPLCSPPQEYLSPQEPTIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2B5</accession>
    <name>E3Q2B5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00360</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089236.1">
        <property type="nucleotide sequence ID" value="XM_008091045.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2B5"/>
    <dbReference type="GeneID" id="24405725"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00360"/>
    <dbReference type="HOGENOM" id="CLU_1777296_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="16"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ25216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="146" mass="16076" checksum="A7A3C797EA75E7CB" modified="2011-01-11" version="1">MAGVIPALAKSMPYEWLPSLGCFAICPSNLFLPVLYAVCTFVCVLMTSNYIKNRPESSVALQLYRPADPQPRVPGHEITEPQPPQTDHEVAETQPLVSGHELPTNIAVGRSFVRCRIQGGLWDEFDMPKGSTLKFNKCSTVITTKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2P4</accession>
    <name>E3Q2P4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Fungal specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_00017</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ24873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008088893.1">
        <property type="nucleotide sequence ID" value="XM_008090702.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2P4"/>
    <dbReference type="STRING" id="645133.E3Q2P4"/>
    <dbReference type="GeneID" id="24405382"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00017"/>
    <dbReference type="eggNOG" id="ENOG502QR2H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009768_0_0_1"/>
    <dbReference type="OrthoDB" id="39175at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF27">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00755">
        <property type="entry name" value="AFLATOXINBRP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="207"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="136"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1011"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="31"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="136"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="1038"/>
            <end position="1047"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ24873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1100" mass="120794" checksum="811FB7299C3C3D2C" modified="2011-01-11" version="1">MSSSSMQQLQSQQFRAASLEYSQQGLDSPGAHSHITTTSSASHQAFSSRTSNDGMPSNNVSQTLIGPSHFANGLSFPPHDLHDQNPIMFLGEPDHASDPFATSHPPSLSSIAARQNTITVMPGPFDRTMGRRRNSVITSEDGSQDSGHADHNPLEDAGADEFGLPTQTAGNGAEPAGKAKEDKTDQTPAWSELKTKAGKERKRLPLACIACRRKKIRCSGEKPACKHCLRSRIPCVYKVTTRKAAPRTDYMAMLDKRLKRMEERIIKIVPKNERDANAASLTRAVVKPAIPGTLPAAKAGSKKRAADEAFGQDLDHWAKAPVKNLLETPNKPTSLRAQEAEDNKLFLEGLDALPSKEIQEHLAEVFFENIYGQAYHLLHKPSYMRKLRAGTLPPVLILSVCAVAARFSSHPKLNSSSPNFLRGEEWASHARDICTRRYEWPNITILTCLLILGLHEFGTCHGGRSWALGGQAIRMAFALQLHKDLDHDPLNRNGSSQLSFIDREIRRRTMWACFLMDRFNSSGTERPTFVREETVDIPLPIKERYFQLDMPAPTETLKGKVPHPVSAEDGQMANAKENMGVAAHMIKTIAFWGRVINYINQGGKELDPHPIWSPESQYATLLEEADRLLDDLPEFLRYSPENLALHDTERMANQFLFLHIAIHQNILFLNRAAVVTPESAAAQGFPSDFVTKAGDKTFAAANRISELLKDAESHMVTAPFVGYCAFSSGTIHILGIFSGNPAVEAASKRNLATNVKFLSKMKRYWGMFHYMSENLRSQYRTYADAARRGSSSKDATTASPIFQYGDWFDRYPHGVSQSDFSDPATQKKKEKGDDAVLEQKPELHTVEEYFTKLSPPRSVEGSSLRPNPSKRKSFAGKKLCMGVRGGGAHSEPLSTENIAATAQEQLSARMQQQRAAQGSLGAQASGSANFNPLGVAHSQGPSYHALSPISPIAVGQFGQHHQGTSPFYPPDWLSMSLHQQSGILQPLDRQLVFGGYSMEQGNMGHFDGIDWDGMPSSAHSASGTHREGARPRPHRGGNPNGMGGPGHGHPDSVAGFGGQEASTAWFMPFNMEPPEIGQDMGMNLDGFGNVFGHSLHHGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2Z2</accession>
    <name>E3Q2Z2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_00115</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ24971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008088991.1">
        <property type="nucleotide sequence ID" value="XM_008090800.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2Z2"/>
    <dbReference type="STRING" id="645133.E3Q2Z2"/>
    <dbReference type="GeneID" id="24405480"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00115"/>
    <dbReference type="eggNOG" id="KOG0585">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_165_1_1"/>
    <dbReference type="OrthoDB" id="68483at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14008">
        <property type="entry name" value="STKc_LKB1_CaMKK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000995">
        <property type="entry name" value="BcCMK3, calcium/calmodulin-dependent protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000447">
        <property type="entry name" value="Calcium/calmodulin dependent protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF77">
        <property type="entry name" value="SERINE THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="103"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="460"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="598"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="461"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ24971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="642" mass="71833" checksum="0A8660241E6D246D" modified="2011-01-11" version="1">MTDSGEPLSPPTTAMALTFIAAPDMPSPTIAVGFHGEGSAGTRPPLAAHISDSTAQQTKFQSPLRHHRRTPSAHREVKETLNAVTQYGAGDHDGSSHHRINQYVIKEEIGRGSYGAVHLATDQFGNEYAVKEFSKARLRKRAQSNILRQGARRPQRFAHRVSLNAPLSPHFGDFGQERKAGWNDNDALFFIREEIAIMKKLNHQNLVQLIEVLDDPEEDSLYMVLEMCKKGVVMKVGLTEKAEPYGEDLCRYWFRDLILGIEYLHEQGIIHRDIKPDNLLLTEDDVLKIVDFGVSEMFEKPGEGMKTAKSAGSPAFLAPELCILRHGDVDGRAADIWSMGVSLYCLRYGKLPFEQDGVLEMYEAIKTESPVLPEDENPDFVDLMNSILEKDPQKRIRMSELREHPWVTKKGTDPLLSKEDNCSVIVELPNELELSRAFTRKMNHLLCVMKAIHKFKGILSRQRQNSKSSRDGYSTPSIPSVDPVREDAQKQDIEALIAKRRAYLTQKGIPLADDRPESEPLILGIGVGLRDEFNKDEPSAGDIAESPTNADFNIYDKAYEAEVERIMKKPTRHPTMYLTRFVKDREHYKEVADVVEGTSQGVTPAGTPRADSHLTASKGRFADLVSSMTGASKSADGEDERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q334</accession>
    <name>E3Q334_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">GDP-mannose transporter</fullName>
            <shortName evidence="7">GMT</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_00157</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 7">Homooligomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Golgi apparatus membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Cytoplasmic vesicle membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Endoplasmic reticulum membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the TPT transporter family. SLC35D subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089033.1">
        <property type="nucleotide sequence ID" value="XM_008090842.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q334"/>
    <dbReference type="GeneID" id="24405522"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00157"/>
    <dbReference type="eggNOG" id="KOG1441">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048347_3_0_1"/>
    <dbReference type="OrthoDB" id="5547497at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030659">
        <property type="term" value="C:cytoplasmic vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="193"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="260"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="291"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="326"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="350"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="9">
        <location>
            <begin position="227"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="38"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ25013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="376" mass="41344" checksum="73E4C65FCBAA4C41" modified="2011-01-11" version="1">MADYRPERTGSIASSSTDAATLHELTKLDPMEDSLQNLKSRADEEVAAEEDEKLLPTTDTSEKEEPPKASLASAVIWMTVNTLATIGIVFTNKAIFSDPQWKLCQLTFASFHFLVTFLTLHILSRPTFAYFTPRRATITDLLPLSVAMCLNVILPNLSLAFSSVTFYQIARILLTPTVALMNFVLYKATLPRNAVLALIPACLGVGMVSYYDTLPAKDGNVKTTSTLGVFFAFAGIFASSLYTVWIASYHRKLQMSSMQLLYNQAPIASFMLLYVIPFVDTFPDWGHVPVNRWLMIGMSGVFASLINISQFFIIAQTGPVSSTVVGHLKTCTIVALGWMVSGRAIGDKSILGVFIAIGGIVGYSVVMLQHQKDRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3L4</accession>
    <name>E3Q3L4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Isoleucine--tRNA ligase, mitochondrial</fullName>
            <ecNumber evidence="3">6.1.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Isoleucyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">GLRG_00760</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>tRNA(Ile) + L-isoleucine + ATP = L-isoleucyl-tRNA(Ile) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:9666"/>
            <dbReference type="Rhea" id="RHEA-COMP:9695"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78528"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.5" evidence="3"/>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089636.1">
        <property type="nucleotide sequence ID" value="XM_008091445.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3L4"/>
    <dbReference type="STRING" id="645133.E3Q3L4"/>
    <dbReference type="GeneID" id="24406125"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00760"/>
    <dbReference type="eggNOG" id="KOG0433">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001493_7_2_1"/>
    <dbReference type="OrthoDB" id="10264412at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004822">
        <property type="term" value="F:isoleucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006428">
        <property type="term" value="P:isoleucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd07960">
        <property type="entry name" value="Anticodon_Ia_Ile_BEm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000111">
        <property type="entry name" value="Mitochondrial isoleucyl-tRNA synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="entry name" value="Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033708">
        <property type="entry name" value="Anticodon_Ile_BEm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002301">
        <property type="entry name" value="Ile-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050081">
        <property type="entry name" value="Ile-tRNA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00392">
        <property type="entry name" value="ileS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42765:SF1">
        <property type="entry name" value="ISOLEUCINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42765">
        <property type="entry name" value="SOLEUCYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00984">
        <property type="entry name" value="TRNASYNTHILE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="ValRS/IleRS/LeuRS editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12 15" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="13">
        <location>
            <begin position="34"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="14">
        <location>
            <begin position="703"/>
            <end position="793"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00068280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EFQ25616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="947" mass="104276" checksum="879739A2CB4D7128" modified="2011-01-11" version="1">MSKSWASTLRLPKSTFPPRPLSQFRADYLRRSADDFYQWQLSNESRPAFSLHDGPPYANGGLHVGHALNKILKDMINRVKVQQGYRVRYRPGWDCHGLPIEMKAVGASGGKGLTATEIRKAARQLASATVLEQMDGFRSYGVMGDWDARWTTMDPDFEIRQLRLFQQMVRRGLIYRKSKPVYWSPSSRTALAEAELEYNENHVSTAAYVRYPITGGPSLSGVSGQLYAIIWTTTPWTLPANKAIAVHEDLDYAVVSAKGASYLTAVSRLEAVKALFPEEEPQVVVSSIKGSELKGLKYHNRLQGVQSAPQPVIHADFVSADSGTGLVHIAPGHGFEDYEACAQLGIDAFAPIDDEGNFTREAFPDAPEKLTEASSILKGGSKAVLALIQDDVLSAAKYKHKYPYDWRTKQPVVMRSTAQWFADVDSIKDDAVDALKDVKFVPASGRNRLESFVVGRSEWCISRQRAWGVPIPALYNADGDAVVTEESVSHIISVIQQRGIDAWFSDAPDEPAWVAPSLKGQFRRGTDTMDVWFDSGSSWTESNGQADVYLEGSDQHRGWFQSSLLSYVAAQRAESDGATRVQPKSPFNTLITHGFTLDQAGKKMSKSIGNTITPAQIMDGTLLPPIKVRGKAKVAGAGPTYEALGPDALRLWVASSEYTKDVAVGQAVLKSVHTILVKYRTIIKMLTGSMHESARTAPTTALDHIALMQLKDVTEEVHQAFAAHEFYKAFNALNRWVANDLSAFYLEAMKDRLYCGDGGGVLEPIFLGFLRMLSPMTPLLVEEAWDHRPEFMKADRALLHPLHTPHDAPIHDRPPSAVGEESLRKDLPVLISVSGAVKAALEKGRLAKVLGSSLQSSVVVTTEDPAVAGVLGKYGEEELEAMFVVSSVETNVEVPPGAAWRYDEAFEVDGAKGTVSVLPPKEHKCPRCWRYVALKEDALCRRCEDVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3Y9</accession>
    <name>E3Q3Y9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_00885</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089761.1">
        <property type="nucleotide sequence ID" value="XM_008091570.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3Y9"/>
    <dbReference type="GeneID" id="24406250"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00885"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_6_1"/>
    <dbReference type="OrthoDB" id="2250022at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000057">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF12">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="328"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="390"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="451"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="68"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ25741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="496" mass="54737" checksum="0D2A2B1A01C3429B" modified="2011-01-11" version="1">MAHHTDSFAAEQPARSAPDIEKQQALHQEQSHVLDDEKKPSAAVDYSGAAAKTDPAEIKLVRKLDLWIMPTLWLMYWLNYLDRNAIALARLNGLEKQLGLSSVEYSTCVSILFVGYILGQIPSNMVLTRVRPSWYMGGFMMAWAVVSALTAVVRDYKGLVLTRFFLGVVEAPYYPGALYILSIFYTRKELATRISVLYSGNILATAFVGLISAGVFHGLEGASGLEGWRWLFILQGAVTLAIALAACFTLPDEPPTTRWLTPVERQLAHARIERDTVGAACVPSSTWAGLREAVVDPKVWVFIYMQHMHLATNGFKNFFPTIVETLNFGTTVTLVLTCPPYLIAGALSIAWAWSSGRRNERTWHITIAKGVALFGFVLACATMNTGARYFAMVVFTVGTYGVNSILLSWVGSTCGQTKEKKASALAIVNTSASISFIWTPYLWPTSDAPRYVIPMASSAAFCVACTAGAWLMRRMLVKENGKIRQSNQEAILFYAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q452</accession>
    <name>E3Q452_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00508</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089384.1">
        <property type="nucleotide sequence ID" value="XM_008091193.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q452"/>
    <dbReference type="GeneID" id="24405873"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00508"/>
    <dbReference type="eggNOG" id="ENOG502RFW0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116369_0_0_1"/>
    <dbReference type="OrthoDB" id="4847539at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="181" mass="19646" checksum="E8CDE4CBD2B76755" modified="2011-01-11" version="1">MGLITGLVSTVVHVAAGRNPYGHNQNHDQAAASAHREGHAGCSAVPGGQPCGICAVALPFGKGRQAKFERRAMKHERKAVRHATKAQRPYGAHGRSFGTVDHAAAGPYYQPQQQQQYQQQYQYQRGMAYSGRQEEGVEEWHERRRASTGADVPPPAYEEGEGSAAGARRRSVEVAGQSEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4B7</accession>
    <name>E3Q4B7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mitochondrial distribution and morphology protein 12</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Mitochondrial inheritance component MDM12</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MDM12</name>
        <name evidence="12" type="ORF">GLRG_00573</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. A MMM1 homodimer associates with one molecule of MDM12 on each side in a pairwise head-to-tail manner, and the SMP-LTD domains of MMM1 and MDM12 generate a continuous hydrophobic tunnel for phospholipid trafficking.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Mitochondrion outer membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
            <orientation evidence="9">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Endoplasmic reticulum membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
            <orientation evidence="9">Cytoplasmic side</orientation>
        </subcellularLocation>
        <text evidence="9">The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the MDM12 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089449.1">
        <property type="nucleotide sequence ID" value="XM_008091258.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4B7"/>
    <dbReference type="STRING" id="645133.E3Q4B7"/>
    <dbReference type="GeneID" id="24405938"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00573"/>
    <dbReference type="eggNOG" id="ENOG502S3PB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026794_0_0_1"/>
    <dbReference type="OrthoDB" id="3356905at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032865">
        <property type="term" value="C:ERMES complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990456">
        <property type="term" value="P:mitochondrion-endoplasmic reticulum membrane tethering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015914">
        <property type="term" value="P:phospholipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045040">
        <property type="term" value="P:protein insertion into mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21672">
        <property type="entry name" value="SMP_Mdm12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03104">
        <property type="entry name" value="Mdm12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027532">
        <property type="entry name" value="Mdm12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28204">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28204:SF1">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26544">
        <property type="entry name" value="Mdm12"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="6" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 9" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SMP-LTD" evidence="11">
        <location>
            <begin position="1"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="64"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="176"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="69"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="197"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="221"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="248"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="262"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ25429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="413" mass="45310" checksum="C15A093341EF16AD" modified="2011-01-11" version="1">MSIDLNWETLTTGPDGEALALRIRDFIHTKFQAVPLPRFIKSVKVHDFEFGAIAPELELKDITDPLPDFYEDNPEIEDDEEEEKALDDPPQLQHFPKSELSAGERRRQREGASMPPRLSMHALRGQSGDFPSPFLGVSTPGILGGTSNLHYFQSHLGNGWSGTQTPLAAVAGAHMGSRLDSSATRSPVGSPRMGHSRNPSQSSISVSDFNPTLAQLREKSSVSTLAPTSAGASRPPTRDAHLAGSAIQEEDEEGPEQGGEGDEPRFREPRPEDLQAVFRIRYAGDVRLRLTAEILLDYPMPSFVGIPVQLSVTGLTFDGVGVMAHIRKRVHFCFLSPEDAVTAVGADDAGPSEPGKRFGGLLQEIQVESEIGLRDGGKQSLKNVGKVERFVLEQVRRIFENEFVYPSFWTFLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4D2</accession>
    <name>E3Q4D2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">homocitrate synthase</fullName>
            <ecNumber evidence="5">2.3.3.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">GLRG_00588</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>acetyl-CoA + 2-oxoglutarate + H2O = (2R)-homocitrate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12929"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58884"/>
            <dbReference type="EC" id="2.3.3.14"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:12930"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-lysine biosynthesis via AAA pathway; L-alpha-aminoadipate from 2-oxoglutarate: step 1/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.14" evidence="5"/>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089464.1">
        <property type="nucleotide sequence ID" value="XM_008091273.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4D2"/>
    <dbReference type="STRING" id="645133.E3Q4D2"/>
    <dbReference type="GeneID" id="24405953"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00588"/>
    <dbReference type="eggNOG" id="KOG2367">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022158_2_2_1"/>
    <dbReference type="OrthoDB" id="2015253at2759"/>
    <dbReference type="UniPathway" id="UPA00033">
        <property type="reaction ID" value="UER00028"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004410">
        <property type="term" value="F:homocitrate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07948">
        <property type="entry name" value="DRE_TIM_HCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.260:FF:000002">
        <property type="entry name" value="Homocitrate synthase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000032">
        <property type="entry name" value="Homocitrate synthase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02222">
        <property type="entry name" value="Homocitr_synth_fung_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050073">
        <property type="entry name" value="2-IPM_HCS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002034">
        <property type="entry name" value="AIPM/Hcit_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048253">
        <property type="entry name" value="DRE_TIM_HCS_fun_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011872">
        <property type="entry name" value="Homocitrate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054691">
        <property type="entry name" value="LeuA/HCS_post-cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02146">
        <property type="entry name" value="LysS_fung_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10277:SF48">
        <property type="entry name" value="HOMOCITRATE SYNTHASE, CYTOSOLIC ISOZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10277">
        <property type="entry name" value="HOMOCITRATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22617">
        <property type="entry name" value="HCS_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00815">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00816">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="15">
        <location>
            <begin position="61"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="453"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="453"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EFQ25444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="482" mass="52506" checksum="BA4E238AE4E50086" modified="2011-01-11" version="1">MCPTPDVPASNGHANGSNGAANGAANGDKADHPGYTAIPTKQKHSNPYQPVGDFLSNVDRYKIIESTLREGEQFANAFFDTETKIKIAKALDDFGVDYIELTSPAASEQSRKDCEAICKLGLKAKILTHVRCHMDDARLAVETGVDGVDVVIGTSSYLREHSHGKDMTYIINTAIEVIEFVKSKGLEIRFSSEDSFRSDLVDLLSVYSAVDKVGVHRVGIADTVGCASPRQVYDLVRTLRGVVSCDIETHFHNDTGCAIANAYCALEAGATHIDTSVIGIGERNGITPLGGLMARMIVAAPEYTKSKYKLHKLKELEDLVAEAVEINIPFNNYITGFCAFTHKAGIHAKAILNNPSTYEIINPADFGMSRYVHFASRLTGWNAIKSRVEQLGLTMTDAQIKVVTQKIKALADVRPIAIDDADSIIRTFHLNITEGEEKPLLPNMTAEEQAKFEKAERELAGEPEKRALDQAAEEPAAKKVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4F0</accession>
    <name>E3Q4F0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Maf-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_00606</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089482.1">
        <property type="nucleotide sequence ID" value="XM_008091291.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4F0"/>
    <dbReference type="STRING" id="645133.E3Q4F0"/>
    <dbReference type="GeneID" id="24405971"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00606"/>
    <dbReference type="eggNOG" id="KOG1509">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040416_0_2_1"/>
    <dbReference type="OrthoDB" id="10267058at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047429">
        <property type="term" value="F:nucleoside triphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00555">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00528">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003697">
        <property type="entry name" value="Maf-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00172">
        <property type="entry name" value="maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43213">
        <property type="entry name" value="BIFUNCTIONAL DTTP/UTP PYROPHOSPHATASE/METHYLTRANSFERASE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43213:SF5">
        <property type="entry name" value="BIFUNCTIONAL DTTP_UTP PYROPHOSPHATASE_METHYLTRANSFERASE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02545">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="ITPase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ25462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="280" mass="30694" checksum="BA8AB6D540FAC77B" modified="2011-01-11" version="1">MADTKTTLDTPPAYIKATEHLSRPRAPSAAAGGPGPRTPLPLNLPIISYLKSKRVVLASASPRRRALLAQVGLTNLEITPSTKPENLDKSAYGPYEYVSETARQKCLDVYETALQTHLASIPDPDVVIAADTVIVTRDGRVLEKPRSEAEHIKMLRHLRDTRVHRVLTSVCVIAPREDARSPGYEIGNHTEETKVYFVQENDGLPDDVIEAYVKTREGADKAGGYAVQGIGGMLLVEKIEGNFDNVVGLPVRQTLSLTEKVVFKQNGEEVGEEDVEEDLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4Y4</accession>
    <name>E3Q4Y4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">WD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_01293</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat CDC20/Fizzy family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ26149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090169.1">
        <property type="nucleotide sequence ID" value="XM_008091978.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4Y4"/>
    <dbReference type="STRING" id="645133.E3Q4Y4"/>
    <dbReference type="GeneID" id="24406658"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01293"/>
    <dbReference type="eggNOG" id="KOG0305">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014831_4_0_1"/>
    <dbReference type="OrthoDB" id="10263272at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0010997">
        <property type="term" value="F:anaphase-promoting complex binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990757">
        <property type="term" value="F:ubiquitin ligase activator activity"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905786">
        <property type="term" value="P:positive regulation of anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000025">
        <property type="entry name" value="FIZZY-related 2 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033010">
        <property type="entry name" value="Cdc20/Fizzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056150">
        <property type="entry name" value="WD40_CDC20-Fz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918">
        <property type="entry name" value="CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918:SF1">
        <property type="entry name" value="FIZZY-RELATED PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24807">
        <property type="entry name" value="WD40_CDC20-Fz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="6" id="KW-0498">Mitosis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="CDC20/Fizzy WD40" evidence="10">
        <location>
            <begin position="298"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="342"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="425"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="555"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="90"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="132"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="179"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="148"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="179"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF24807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ26149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="611" mass="67589" checksum="30779723BEFC63D5" modified="2011-01-11" version="1">MTIPVDSSAAIAAHTSTKRPVAETSDSAAATPPRFATPPPPSDRGHLEDRQNLENTNQRKIQRSRRPSELARVNGFDADAVDSALLREMHHRSQRESTPGASPHRKRQRINGDRFIPTRSGQDLQASFSLLHEDGSPATPSKQKKRTPHGELHFQKTEEANRTFSTLLRAELFEGSIPQATPSVMSPEHSLSTASHSAHIRDGTRSRTPPNNASTTSLPSSLTPSTPHKNLFSYMSPRQLSNAGHLTPSRTPQSRHGPNLDTRSEIYSLSPVRFNSQQMLLSPRRQPRAVSKVPYKVLDAPDLADDFYLNLVDWGSANVLGVGLGSSVYMWNAQTSRVNKLCTLEDDTVTSVSWIQKGTHIAIGTGKGLVQIWDAEKTRRLRTMTGHTARVGSLAWNTHILTSGSRDRLIYHRDVRAPDQWLRKLVGHKQEVCGLKWNCEDGQLASGGNDNKLMVWDKLSETPLWKFSDHTAAVKAIAWSPHQRGLLASGGGTADRRIIFHDTARGSVINEVDTGSQVCNIAWSKNSNEIVSTHGYSQNQIVVWKYPSMTQVVSLTGHTYRVLYLAMSPDGRTVVTGAGDETLRFWNVFGRRPGAREDSDGGRLSDWGVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q615</accession>
    <name>E3Q615_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">DNA replication licensing factor MCM4</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">DNA replication licensing factor mcm4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">GLRG_01407</name>
    </gene>
    <organism evidence="19">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the MCM family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090283.1">
        <property type="nucleotide sequence ID" value="XM_008092092.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q615"/>
    <dbReference type="STRING" id="645133.E3Q615"/>
    <dbReference type="GeneID" id="24406772"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01407"/>
    <dbReference type="eggNOG" id="KOG0478">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000995_7_1_1"/>
    <dbReference type="OrthoDB" id="10251574at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031261">
        <property type="term" value="C:DNA replication preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097373">
        <property type="term" value="C:MCM core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005656">
        <property type="term" value="C:nuclear pre-replicative complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902975">
        <property type="term" value="P:mitotic DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006279">
        <property type="term" value="P:premeiotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17755">
        <property type="entry name" value="MCM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.10:FF:000003">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1640.10:FF:000011">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000217">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008047">
        <property type="entry name" value="MCM_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF66">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21128">
        <property type="entry name" value="WHD_MCM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01660">
        <property type="entry name" value="MCMPROTEIN4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0235">DNA replication</keyword>
    <keyword evidence="10 15" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="17">
        <location>
            <begin position="611"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="335"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="571"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="81"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="164"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="203"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="344"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="589"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00073498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00074938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EFQ26263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1031" mass="113499" checksum="4C51CC7213B1758F" modified="2011-01-11" version="1">MSSPSKRSTRSSTAGTPRRSTRNNPDAAARSSPAPADEEAQRPAETPRTSRRSQLASSPLFYESSPAQTPSGRRDAPANGDVSSPLRNMSNSQSTVVGPAPSSPLRQDIDTQSTGDGDRTPRASGLARESSPIRYEASSSPGRSVRPLQSDFRSESSGLFVTDRSSRSRRGDINSEGVRTPRRRLVLDPSGRVTTDAPGSDAPSFSNPDPNTSEADRLGGAGESTIWGTTVSIDDTFASFKDFLRHFTRKYQLYRDGWSEADVQAAPDAESKPYMEALENMLLLGTTRLYLDIADLNTYPPTRKLWYHIQAYPQEIIPIMDQSVHDLMVELARNEGQRQRASQSSAGDAARRSNAAASSDVAFPSSDHPGSDAPTPRPATDVPSKEDEVAQMIYMVRPFGLDKTTNLRDLNPSDMDRLITIKGLVIRTTPVIPDMKEAFFRCNVCNHSVNVGLDRGKIREPTECPRPRCASKNSMQIIHNRCAFEDKQVIKLQETPDAVPAGQTPHSVSVCVYNELVDFCKAGDRVQLTGIFRVSPVRVNPRQRTIKSVYKTYVDVLHVQKVDKKRMDVDPSTLGIEGEEDEGGANNIEETKKISPEEEEKIRETAARPDIYDLLSRSLAPSIYEMDDVKKGILLQLFGGTNKTFSKGGSPRYRGDINVLLCGDPSTSKSQILSYVHKIAPRGVYTSGKGSSAVGLTAYVTRDPETRQLVLESGALVLSDGGVCCIDEFDKMSEATRSVLHEVMEQQTVSVAKAGIITTLNARTSILASANPIGSRYNPDLPVPQNIDLPPTLLSRFDLVYLILDRADEKSDARLARHLLSLYLEDKPESAHTKEDILPVEFLTNYISFARANIHPTIAQDAAQELVDQYLEMRKLGQDVRAAEKRITATTRQLESMIRLSEAHAKMRLSTTVVREDVKEAARLIRSALKTAATDAQGRIDMSLLTEGTSAADRRKKEEIKGAVLHLLDEMTSNGQTVRWSEVARRLSEGASMPVEQNDFNESMRTLEMEGLIMISGEGARRSVRRVTAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6B8</accession>
    <name>E3Q6B8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Cytidine deaminase</fullName>
            <ecNumber evidence="4 13">3.5.4.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 13">Cytidine aminohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">GLRG_01510</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 13">This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>2'-deoxycytidine + H2O + H(+) = 2'-deoxyuridine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13433"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15698"/>
            <dbReference type="ChEBI" id="CHEBI:16450"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 13">
            <text>cytidine + H2O + H(+) = uridine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16069"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16704"/>
            <dbReference type="ChEBI" id="CHEBI:17562"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12 13">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.5" evidence="4 13"/>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090386.1">
        <property type="nucleotide sequence ID" value="XM_008092195.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6B8"/>
    <dbReference type="STRING" id="645133.E3Q6B8"/>
    <dbReference type="GeneID" id="24406875"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01510"/>
    <dbReference type="eggNOG" id="KOG0833">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097262_2_2_1"/>
    <dbReference type="OrthoDB" id="414540at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004126">
        <property type="term" value="F:cytidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055086">
        <property type="term" value="P:nucleobase-containing small molecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072527">
        <property type="term" value="P:pyrimidine-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01283">
        <property type="entry name" value="cytidine_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000008">
        <property type="entry name" value="Cytidine deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050202">
        <property type="entry name" value="Cyt/Deoxycyt_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006262">
        <property type="entry name" value="Cyt_deam_tetra"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01354">
        <property type="entry name" value="cyt_deam_tetra"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004064">
        <property type="entry name" value="PRK05578.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11644">
        <property type="entry name" value="CYTIDINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11644:SF2">
        <property type="entry name" value="CYTIDINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12 13" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="14">
        <location>
            <begin position="28"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="69"/>
            <end position="75"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR606262-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR606262-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR606262-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU364006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EFQ26366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="171" mass="18483" checksum="84E46E2F0FBD0AA3" modified="2011-01-11" version="1">MAFTPEIFDIANESQTTETAKKYGLTPAEVKELHLRATAAKATAYCPYSQFRVGSTLLSNDGQYTAGANVENASYPVGTCAERVAFGKAITEGIRGFKAVAVATDIEAPCSPCGMCRQFIREFVDLETPILMFNKDGKYAAMRLETLLPLSFGPEYLPPPDVLQKSRAGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7Z9</accession>
    <name>E3Q7Z9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GTP-binding protein SAR1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02182</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091031.1">
        <property type="nucleotide sequence ID" value="XM_008092840.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7Z9"/>
    <dbReference type="STRING" id="645133.E3Q7Z9"/>
    <dbReference type="GeneID" id="24407547"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02182"/>
    <dbReference type="eggNOG" id="ENOG502S9SC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014084_0_0_1"/>
    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018853">
        <property type="entry name" value="DUF2457"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10446">
        <property type="entry name" value="DUF2457"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="316"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="492"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="404"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="424"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="437"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="504"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="519"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="541"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="720" mass="80367" checksum="B277267C57478794" modified="2011-01-11" version="1">MTHLATHDAATSNVLAWSANCANTPLMVEDEPADVDEPPDNMQQPPLSPMNSMFKRNPIRRTTVDHNASLLTKALHSPSEDEDSEARPGMSFFARRRSMASNISLASTAELTSDTGLTSPSRANTPSPPLPEIRLLNLDGAPAKDAPKKRCIQFACAAKPKVAEPIQAQPMVKAPSAQETRRKTCVKFACPVPQRPASTQNTPPQRMEMAAARLQPAALDKQASPTMARRARSSVTRSQSPGPFLAPPHADKDARSPTTKKYITANDNDLNNESSRFHEFASDIPREEDWIRQAFSSQGRRITINDTLQKENAIRKLATEAEEEAEQEEEDMALEDDEDLDNMDDADDVDEDEDQDDEDEDDDEDGASDEDDNSDGYKTDEETGFADSEEEEEEDEDLRLWTPGRSTVLNIDSTPIARRPSLPEQLSDSSIASKTSLRARRGRTQRLKIRPGTPELPDSTDFVCGTLDEDRPMEDAYMSCLAARRREKLQLIPQDIDPSFPASDPEDEGEEEIYNPVHHSSDDEMFFHGKMDDLHHANDRSRRRKKTEHTSPKRFHSPPPLKRRASPAPKARGRSPRRLFDGPSPHRLRSPAPQTLRSPPASPRNGDGGIAFKTLASRPGLTVTKSLPRPPSMFPHMAKGRRIKAPANDVHIRGAIDIVKGLEQKRQRRKEKFYQKYCNRARKGQVPERKPQRGLGCERMRELGLLMAGKIGQGNYVISV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q851</accession>
    <name>E3Q851_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12 15">Catalase</fullName>
            <ecNumber evidence="4 12 15">1.11.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">GLRG_02234</name>
    </gene>
    <organism evidence="20">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Catalyzes the degradation of hydrogen peroxide (H(2)O(2)) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide.</text>
    </comment>
    <comment type="function">
        <text evidence="2 12">Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12 15">
            <text>2 H2O2 = O2 + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:20309"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="EC" id="1.11.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12 14">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 12 15">Belongs to the catalase family.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.6" evidence="4 12 15"/>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091083.1">
        <property type="nucleotide sequence ID" value="XM_008092892.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q851"/>
    <dbReference type="STRING" id="645133.E3Q851"/>
    <dbReference type="PeroxiBase" id="8415">
        <property type="entry name" value="CgraKat02"/>
    </dbReference>
    <dbReference type="GeneID" id="24407599"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02234"/>
    <dbReference type="eggNOG" id="KOG0047">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010645_3_0_1"/>
    <dbReference type="OrthoDB" id="6880011at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03132">
        <property type="entry name" value="GATase1_catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.180.10:FF:000003">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1370.20:FF:000001">
        <property type="entry name" value="Catalase HPII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1370.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.180.10">
        <property type="entry name" value="Catalase core domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018028">
        <property type="entry name" value="Catalase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024708">
        <property type="entry name" value="Catalase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024712">
        <property type="entry name" value="Catalase_clade2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043156">
        <property type="entry name" value="Catalase_clade2_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011614">
        <property type="entry name" value="Catalase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002226">
        <property type="entry name" value="Catalase_haem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010582">
        <property type="entry name" value="Catalase_immune_responsive"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041399">
        <property type="entry name" value="Catalase_large_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020835">
        <property type="entry name" value="Catalase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42821">
        <property type="entry name" value="CATALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42821:SF3">
        <property type="entry name" value="CATALASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00199">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06628">
        <property type="entry name" value="Catalase-rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18011">
        <property type="entry name" value="Catalase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038927">
        <property type="entry name" value="Catalase_clade2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00067">
        <property type="entry name" value="CATALASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01060">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56634">
        <property type="entry name" value="Heme-dependent catalase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00437">
        <property type="entry name" value="CATALASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00438">
        <property type="entry name" value="CATALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51402">
        <property type="entry name" value="CATALASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12 15" id="KW-0349">Heme</keyword>
    <keyword evidence="10 12 15" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="9 12 14" id="KW-0408">Iron</keyword>
    <keyword evidence="7 12 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 12 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 12 15" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="17" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178276" description="Catalase" evidence="17">
        <location>
            <begin position="19"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="domain" description="Catalase core" evidence="18">
        <location>
            <begin position="56"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="active site" evidence="13">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <feature type="active site" evidence="13">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="389"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR038927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR038927-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR038927-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU004142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM01060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EFQ27063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="715" mass="77452" checksum="00C5004A659984AA" modified="2011-01-11" version="1">MHTTLLLAGLSLATLSSAGCPFADPSNIKARAEGGGSRSHVAANEIDDLSGDPFLTSDVGGPIGDQVSLKAGVRGSTLLEDFIFRQKITHFDHERVPERAVHARGAGAYGTFTSYGDFSNLTAAYFLSAAGKNTSTFVRFSTVAGSRGSSDTARDVHGFATRFFTDQGNFDIVGNNIPVFFIQDAIQFPDLVHAVKPRGDNEIPQAATAHDSAWDFFSSQTSSLHTLFWAMAGYGIPRSYRHMDGFGVHTFRMVTNDGKSKLIKWHWKTLQGKASLVWEEAQIVSGKNADYHRQDLFDAIASGNGPEWELAVQVIDESDVLKFGFDLLDPTKIVPVELAPLQKLGKMKLDANPVNYFAETEQIMFQPGHIVRGIDFTEDPLLQGRIFSYLDTQLNRHGGPNFEQLPINRPVTPIHNNNRDGAAQNFIHRNRNSYFPNALNKNVPKQASQAEGNGFFTTPGRAVGGTLVRDISGTFADHWSQPRLFYNSLTPIEQQFLVNAIRFETSHIESPDVKNNVVVQLNKISNEVAGRVADALGIVKPAPDPQFYNNNTTQGITIFGEKLPTIATLKVGVLASLAADGSVVQGKQLKDAFAPSGVIVTIVGERLGNGVDMTYSQADATAFDGIIVTNGAQGLFDGTIKPSALYPAGRPAQMVIDSYRWGKPVGSIGKPLPDTAVLGVRPGAGVFASPDINVVVAGFKDGLATFRFTDRFAMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8B3</accession>
    <name>E3Q8B3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">triacylglycerol lipase</fullName>
            <ecNumber evidence="6">3.1.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Autophagy-related protein 15</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">GLRG_02296</name>
    </gene>
    <organism evidence="23">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies. Involved in the lysis of intravacuolar multivesicular body (MVB) vesicles. The intravacuolar membrane disintegration by ATG15 is critical to life span extension.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12044"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17855"/>
            <dbReference type="ChEBI" id="CHEBI:18035"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="EC" id="3.1.1.3"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Binds to both phosphatidylinositol (PI) and phosphatidylinositol 3,5-bisphosphate (PIP2).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endosome</location>
            <location evidence="3">Multivesicular body membrane</location>
            <topology evidence="3">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Prevacuolar compartment membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.3" evidence="6"/>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091145.1">
        <property type="nucleotide sequence ID" value="XM_008092954.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8B3"/>
    <dbReference type="STRING" id="645133.E3Q8B3"/>
    <dbReference type="ESTHER" id="colgm-e3q8b3">
        <property type="family name" value="ATG15-related-lipase"/>
    </dbReference>
    <dbReference type="GeneID" id="24407661"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02296"/>
    <dbReference type="eggNOG" id="KOG4540">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028295_0_1_1"/>
    <dbReference type="OrthoDB" id="58570at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032585">
        <property type="term" value="C:multivesicular body membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005775">
        <property type="term" value="C:vacuolar lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004620">
        <property type="term" value="F:phospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034496">
        <property type="term" value="P:multivesicular body membrane disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046461">
        <property type="term" value="P:neutral lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006660">
        <property type="term" value="P:phosphatidylserine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000129">
        <property type="entry name" value="Autophagy related lipase Atg15, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050805">
        <property type="entry name" value="ATG15_Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47175">
        <property type="entry name" value="LIPASE ATG15-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47175:SF2">
        <property type="entry name" value="LIPASE ATG15-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0072">Autophagy</keyword>
    <keyword evidence="8" id="KW-0967">Endosome</keyword>
    <keyword evidence="16" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="14" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="20" id="KW-0732">Signal</keyword>
    <keyword evidence="11" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="20">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180222" description="triacylglycerol lipase" evidence="20">
        <location>
            <begin position="34"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="domain" description="Fungal lipase-type" evidence="21">
        <location>
            <begin position="296"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="568"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="568"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00024663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00029828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="EFQ27125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="623" mass="67544" checksum="FB32ADD67443F059" modified="2011-01-11" version="1">MKLRLGGRGECTSAGRVTAHLLLSFLAISPTLASVGEAFNHKEAALQPGPLLPPSTQQPASAEHLFTLRHVFHHGTYRHPQLHRRKDVRHLDDAGSQVWLAEEDGFKREKVMPLTAKSAPLKIERMVDRRPSVVDPMVTEARQRGYVNIMSPSDWTLDEVPGPNITDKATVISLAIMAANAYIEEEGKADWEEVGGPYNRSADFGWETDGLRGHIWADSTNSTVVIGLKGTSTAIFDGEGTTTNDKVNDNLFFSCCCAQQGQWTWHQVCDCATSTYSCNNTCVVEALRDEHRYYTAAKELYSNVTEIFPDANIWLSGHSLGGAVSSLLGLTYGLPTVTFEAVPEALAAGRLGLPVPPGADQMVHQARQNTGAYHFGHTADPIYIGTCNGATATCSFAGYAMESACHTGLECVYDVVADKGWRVGIGTHKIRSVIHDVIMKYDNVPECKATPECRDCANWKMYESNGTETTTTSRSSTTSKTRTRTETCQTPGWWGCLDETTTTPVTTTTSTSTTSTCKTPGWFGCKDETTTTTTTTTTSTTTSATTTCLTPGWFGCKDKTTATSTTTLLPGSTPAHGITAAPTATPTSAPTKAPPSDPHCQRRSWFGWCKEWSQASESSNEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8B9</accession>
    <name>E3Q8B9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">CHY zinc finger</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_02302</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091151.1">
        <property type="nucleotide sequence ID" value="XM_008092960.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8B9"/>
    <dbReference type="STRING" id="645133.E3Q8B9"/>
    <dbReference type="GeneID" id="24407667"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02302"/>
    <dbReference type="eggNOG" id="KOG1940">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_140539_0_0_1"/>
    <dbReference type="OrthoDB" id="411372at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045041">
        <property type="term" value="P:protein import into mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052604">
        <property type="entry name" value="Mito_Tim_assembly_helper"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008913">
        <property type="entry name" value="Znf_CHY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037274">
        <property type="entry name" value="Znf_CHY_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28082:SF2">
        <property type="entry name" value="CHY-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28082">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05495">
        <property type="entry name" value="zf-CHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161219">
        <property type="entry name" value="CHY zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51266">
        <property type="entry name" value="ZF_CHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CHY-type" evidence="5">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ27131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="122" mass="14050" checksum="13F0F0A6A24B795A" modified="2011-01-11" version="1">MCKHILNAQVAIRSPCCKKWFDCADCHHEQEKHPLMQSLEMVFACKKCKKCFRKDATEFEESDEYCPHCDNHFVIEAKTPKAAISVEGEDARKDSRMIKDERVRQVAGRSIFDPTDDADKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9A3</accession>
    <name>E3Q9A3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_01777</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091302.1">
        <property type="nucleotide sequence ID" value="XM_008093111.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9A3"/>
    <dbReference type="GeneID" id="24407142"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01777"/>
    <dbReference type="HOGENOM" id="CLU_1948678_0_0_1"/>
    <dbReference type="OrthoDB" id="3222723at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="129" mass="14462" checksum="EA1972DD4E625291" modified="2011-01-11" version="1">MARALDVEPTVSGNGTSYLITKLLTPDVAFNETAYQEFGPPFVGTHVLLTIFFNYAAYTSAMWARWNHILAAAFDGGFNFNMMLTFLVFGAGKIVTMPYCEYSFLLSITCLVFIYILLTFWPRAGQRGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9C2</accession>
    <name>E3Q9C2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450 4V3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_01796</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091321.1">
        <property type="nucleotide sequence ID" value="XM_008093130.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9C2"/>
    <dbReference type="STRING" id="645133.E3Q9C2"/>
    <dbReference type="GeneID" id="24407161"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01796"/>
    <dbReference type="eggNOG" id="KOG0158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020492_1_0_1"/>
    <dbReference type="OrthoDB" id="10029320at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF107">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="379"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ27301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="448" mass="50413" checksum="E342522B1FF029D7" modified="2011-01-11" version="1">MFTNDPDVAAQGVAEPSIPRSDYIKSIIKPLTDGLDLVSSEGETWKTWRSRFNPSFSNKNVLALVPGMIKDVQVFTDLLRKQAGVGGGWGDVFPLEDLTTNLTIDVIGRAVLDIELNEQTAGPSRFKKHFTDQISRFVTGRNIVTIWKWYSPWRLSAIARNTHAMRSELLPSIERSLSENKIKKSSGKTIIDLALKPIKSAADEEKAPVTDQLFIDTVISQLKLFMFAGYDTTATTLCWVLHCIAKNPEVARKLRAEHNKILGEDPAMAAENLRQSPHLINSLLYTGGIIKEALRLDPGPASLRDGQPHYSIIDKETGDRYPTDGFIVWDAMRSRSLSEELWPRAKEVVPERWVTTNESDPLHPKKHAWRMFGVGPRNCIGQELAVIEMKMVLVFMAREIDLDCAWDKWNAKRNHTTPRPVCGKDGCFQVGRGTPHLKDGMPIHVRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9F6</accession>
    <name>E3Q9F6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sodium:neurotransmitter symporter family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_01830</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091355.1">
        <property type="nucleotide sequence ID" value="XM_008093164.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9F6"/>
    <dbReference type="STRING" id="645133.E3Q9F6"/>
    <dbReference type="GeneID" id="24407195"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01830"/>
    <dbReference type="eggNOG" id="KOG3659">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016501_0_0_1"/>
    <dbReference type="OrthoDB" id="6581954at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035725">
        <property type="term" value="P:sodium ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11554">
        <property type="entry name" value="SLC6sbd_u2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616:SF240">
        <property type="entry name" value="BLOATED TUBULES, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616">
        <property type="entry name" value="SODIUM/CHLORIDE DEPENDENT TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00176">
        <property type="entry name" value="NANEUSMPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SNF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="61"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="107"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="256"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="293"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="349"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="388"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="423"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="454"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="481"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="548"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="581"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="644"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="650"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ27335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="677" mass="74377" checksum="79D90C277EF0CEE9" modified="2011-01-11" version="1">MDMLKKIGAWFAPPPNKAEDGRDAWPSRASFLLASMGGCAGMGNLLRYPSQVYNNHGLQWYIPYLMAVFIVAIPVLVLEIAIGQAYRGGSVVAYNNLNQRLKGTGLSLLYVGFVVTPYFVVNLAWIMSYFRHSFTSPLPWTGRGEEFFNRDVVSNVDPIEGSLTADGTSVLNYTQYPGIGLIGETTGWAAFTFFLMWVSIFRGVGLTGRVVYFTMGLPIVVTIILIGRSVSLENAGEGVKLYFATWRGSELAKGTVWQTACGQVFFSTGVGFGYFTSYASYNRQYSNAVMDSILIVCSNVLFENIAAFAVFGVVGYLGMRPDPENPIGGFTVGFLTLPLAVAEMPGANFWAVALFFTLMVLGYSSAFAMLDAIVTLVMDTGIKFSRPIVVTALTILSFLLALPYCTEFGYYLLTGIDRWVNDIALVFVVFAECITSTSVYRCKDVIGQVGKPAFIIYNTCYILAMVLGVAVAHAVQAGAGAGVGLGLFFAGCIVSVLVSKTPDATPPRFWGRNVFVSRFWYLAFYSGNQLRRDLNVVIGSGKNWNIPIFWPVLLRYISGPILSIVYGFSYPAFYQVRYDPLHILGFAVVHVALVMIFASFMVPRWFNVFIPVHRRQEGKVHYAPLITIGADEAQAIAAGNMEQGQIHTSSHSDEGVGRKELPTHDGLIMEDEKRANI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9V3</accession>
    <name>E3Q9V3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_02785</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091661.1">
        <property type="nucleotide sequence ID" value="XM_008093470.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9V3"/>
    <dbReference type="STRING" id="645133.E3Q9V3"/>
    <dbReference type="GeneID" id="24408150"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02785"/>
    <dbReference type="eggNOG" id="KOG1187">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006696_0_1_1"/>
    <dbReference type="OrthoDB" id="635774at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050167">
        <property type="entry name" value="Ser_Thr_protein_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257:SF963">
        <property type="entry name" value="AT08303P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257">
        <property type="entry name" value="SERINE-THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="325"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="674"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="890"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="897"/>
            <end position="913"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ27641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="971" mass="107648" checksum="F16810566AEE4A58" modified="2011-01-11" version="1">MAQTSPSPTEPPPTSGHHSTSFLRKLFGRNNAAPAPVGPLQAKEPEPEPGHEPDPDDPQSTGLVRRVSRKVVPGLPRVQTFKRQQSERRNNLAPVEPSPAERRALSVDRRVQSPRTASQAQSFPRASAPDFLENTYEIQSASSAPASPVEEKAEASLNQMVAPVSAPTFDDSHVHELQSNSDAHSVTTSQSQYEAMIHDELETTWILNLSMHFRDKSKREKFFVTYRETPTLWRRVTISLDYRNAPDNSLELDLMHTKSQRDKSSKIYEAIRDSLQDIQFYHSVTNLKLQTTDGRLHVHVVEDVNEIIQYPTVRQVQHLGCRRIRERDIDFDSHMSGFVYKVRVGGDVLIKKEIPGPDTIDEFLYEINALNRLRYSRNIIRFHGVVVDDDDEYVKGLLISYAVHGALIDVIYDNQQESELGLPWPVREKWARQIVQGLADIHESGFVQGDFTLSNIVIDDEDNAKIIDINRRGCPVGWEPPEATPLIESNQRISMYIGVKSDLYQLGMVLWALAAQDDEPEAQGRPLQLTEEHIVPAWYREMVDICLSDDPRLRLQASSLMALFPEPAVGDDAAPPSISVDDGYTMQEYFVEGYQGNGHARVKTAEPAHDWSYVNLGHTYADPTRGFSQDPYYYTRGRSPPSPLPSHYGRCDSPHMGRNISSWAEARNIAPSYSDVGGDEIDDHKSTTPTTSKDSIATPELTDETSRSMQQRLEELQWTPLSNDFAAIDRAELDQTPGQVDKRLAGEELSRVVSGTELTEPHAFVDPIASRPSMASPLTVKNVDIEGDNAGGDIMEEAGQVGNGQYAEPDAKETAGQTVPLVTGKTEPKNQLNSNDISSESGNIAVATQLMEHEDRATTPSTKYTTTANPTAAEFEAENESVDVAEQQILPALDAKIPSKDDTTPKTDTDDKTAAPSSPVAGNPELNGVGAAYLDTDEQKMREKESLDDDFSSNTVALAAPTATMMTAVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>E3QB76</accession>
    <name>E3QB76_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="22">DNA polymerase</fullName>
            <ecNumber evidence="22">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="27" type="ORF">GLRG_03258</name>
    </gene>
    <organism evidence="28">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="28" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="28">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="29">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 22">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 22">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 22">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="22"/>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ28114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092134.1">
        <property type="nucleotide sequence ID" value="XM_008093943.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QB76"/>
    <dbReference type="STRING" id="645133.E3QB76"/>
    <dbReference type="GeneID" id="24408623"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03258"/>
    <dbReference type="eggNOG" id="KOG0969">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000203_2_0_1"/>
    <dbReference type="OrthoDB" id="2414538at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043625">
        <property type="term" value="C:delta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008296">
        <property type="term" value="F:3'-5'-DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006287">
        <property type="term" value="P:base-excision repair, gap-filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045004">
        <property type="term" value="P:DNA replication proofreading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006297">
        <property type="term" value="P:nucleotide-excision repair, DNA gap filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05777">
        <property type="entry name" value="DNA_polB_delta_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05533">
        <property type="entry name" value="POLBc_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.132.60:FF:000001">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.690:FF:000001">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.342.10:FF:000009">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000004">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.60">
        <property type="entry name" value="DNA polymerase family B, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.342.10">
        <property type="entry name" value="DNA Polymerase, chain B, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.690">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="entry name" value="Palm domain of DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006172">
        <property type="entry name" value="DNA-dir_DNA_pol_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017964">
        <property type="entry name" value="DNA-dir_DNA_pol_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006133">
        <property type="entry name" value="DNA-dir_DNA_pol_B_exonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006134">
        <property type="entry name" value="DNA-dir_DNA_pol_B_multi_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042087">
        <property type="entry name" value="DNA_pol_B_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050240">
        <property type="entry name" value="DNA_pol_type-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025687">
        <property type="entry name" value="Znf-C4pol"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00592">
        <property type="entry name" value="pol2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10322">
        <property type="entry name" value="DNA POLYMERASE CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10322:SF23">
        <property type="entry name" value="DNA POLYMERASE DELTA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00136">
        <property type="entry name" value="DNA_pol_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03104">
        <property type="entry name" value="DNA_pol_B_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14260">
        <property type="entry name" value="zf-C4pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00106">
        <property type="entry name" value="DNAPOLB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00486">
        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00116">
        <property type="entry name" value="DNA_POLYMERASE_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 22" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8 22" id="KW-0235">DNA replication</keyword>
    <keyword evidence="18 22" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="15 22" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="14" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="16 22" id="KW-0408">Iron</keyword>
    <keyword evidence="17 22" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="10 22" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7 22" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="20 22" id="KW-0539">Nucleus</keyword>
    <keyword evidence="28" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 22" id="KW-0808">Transferase</keyword>
    <keyword evidence="13 22" id="KW-0862">Zinc</keyword>
    <keyword evidence="11 22" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DNA-directed DNA polymerase family B exonuclease" evidence="25">
        <location>
            <begin position="238"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B multifunctional" evidence="24">
        <location>
            <begin position="535"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="domain" description="C4-type zinc-finger of DNA polymerase delta" evidence="26">
        <location>
            <begin position="1004"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="423"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="23">
        <location>
            <begin position="14"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="RuleBase" id="RU000442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF00136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="Pfam" id="PF03104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="Pfam" id="PF14260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="EMBL" id="EFQ28114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1103" mass="124904" checksum="2D3BB1008DFC567C" modified="2011-01-11" version="1">MATVLPQKRVLGETPSTRRNIPSTPSSLKKRKVESFSSSPAHHFGSQRDAKGLPGSSQPKSAFESEVLEKLSQDIADRKQNNTEKDQAWERPPLVDFDPARDNLIFQQIEAEEGSLHGGRATVKLFGVTEKGHSVMLHVTDFKHYLYVAAPVAFRPEDCNAFKAYLESQVAQHQPCIHSVAFLMRENIYGFQGNVKSPYLKITVMDPKFISRVRTTIESGNANWKGMWKGMDGGVMTFDNIQYVLRFMVDCKIFGMSWVEAPASKYQVLPQSQRQSNCQIEAEISHLDLIAHKPVGEWSKMAPLRIMSFDIECAGRKGIFPEATHDPVIQIANVVTRYGEKKPFVRNVFCLDTTSPIVATQILDFEKEEKMLSEWQKFLIKVDPDILIGYNIANFDFPYLLDRAKHLKVPGFEYWSRIPSMPSRAKETNFSSKQMGNRDSKATNTNGRLQLDLLQLVQRDYHLRSYTLNSVCSQFLGEQKEDVHHTMITELFNGTPESRRRLALYCLKDAYLPQRLMDKLSCLENYTEMARVTGIPFNFLLSRGQQVKFISQLFRKALEQKLVIPNMRSEGTDEQYEGATVIEPTRGYYDVPIATLDFASLYPSIMQAHNLCYTTLVNKKAIEKFQLKKDDDYIVTPNGDTFVTTKQRKGLLAQILEELLTARKQAKRELAMETDPFKKAVLNGRQLALKISANSVYGLTGATTGKLPCLEIASSTTSFGRQMIMKTKEEVEKKYCIANGYSHDAQVIYGDTDSVMVKFGTKDLPEAMKFGEEAAAYVSSKFVKPIKLEFEKVYYPYLLINKKRYAGLYWTKPEKYDKMDTKGIETVRRDNCLLVQTVIEKVLRMILIDQDVQGAQDYVKDTIADLLQNKVDMSKLVITKALTKDDYAAKQAHVELAQRMKKRDAGSAPGLGDRVAYVMIKGAAGSKNYEKSEDPIYVLENNVPIDTKYYLDNQLAKPLGRIFEPILGETKANSLLTGAHTRTIAVSAPTVGGLMKFAKKTQTCMGCKKPLRGKEESEGAVCSDCAPRVGELYKKTLDKVSDLEVRFGRLWTQCQRCQGSMHCEVICSSKDCPIFYMRMKAKKDLEDAGKELTRFDFDQAAIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBA1</accession>
    <name>E3QBA1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_03283</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ28139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092159.1">
        <property type="nucleotide sequence ID" value="XM_008093968.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBA1"/>
    <dbReference type="GeneID" id="24408648"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03283"/>
    <dbReference type="eggNOG" id="ENOG502SU37">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141137_1_0_1"/>
    <dbReference type="OrthoDB" id="5201563at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ28139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="123" mass="14005" checksum="421346166513E342" modified="2011-01-11" version="1">MSATVTENPVTSTIQQDYLHDYQIRLTGGIEEAFARRNEDAPAPAAEYPPGWYDQHRQVPPYRPVNRNLDLADRPWGSNGIESTFVYLMMNGCWLQGIASWLWRGTGERVNKSFFRAKVGGEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBQ7</accession>
    <name>E3QBQ7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MATE efflux family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_03540</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092416.1">
        <property type="nucleotide sequence ID" value="XM_008094225.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBQ7"/>
    <dbReference type="STRING" id="645133.E3QBQ7"/>
    <dbReference type="GeneID" id="24408905"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03540"/>
    <dbReference type="eggNOG" id="KOG1347">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012893_1_2_1"/>
    <dbReference type="OrthoDB" id="2126698at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990961">
        <property type="term" value="P:xenobiotic detoxification by transmembrane export across the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13132">
        <property type="entry name" value="MATE_eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045069">
        <property type="entry name" value="MATE_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11206">
        <property type="entry name" value="MULTIDRUG RESISTANCE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="82"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="271"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="344"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="418"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="447"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="484"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ28396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="504" mass="53884" checksum="CFA05DA6A87001BC" modified="2011-01-11" version="1">MAESSSSDTLGPLAVQPQSETTALLPKPPASAPDGSYPIRRWLAEILLLGKAAIPVILAYTLQNSLQTLSVLIVGRLSPEALATAAFSYMFAMATAWLIALGGTTALDTLASSSFTGSSNKHDLGILLQRGMIVLSAFYAVVAVLWWFSEPVFRALGQEEFICVQSSVFLRWLIPGGLGYVWFEAMKKYLQAQAIYRPGTYVLLITSPLNAGLNYLFIHTFGLGLYGAPIATGISYWVSFMLLVAYAVFVRGKECWGGLELRKAVRNIGPFAKLAVMGVVHVGTEWWAFEIVALAAGRLGTIPLAAQSVIMTADQIINTIPFGLGVAASARLGNLLGAQRPRDAAIAAHSAAILSVLLGTIVLTVLMATKDVFGKIFNDDERVIRLVGEVMPYVALFQIADGLNGSCGGALRGMGRQWVGAVVNLISYYGGALPAGIYLAFNGWGLAGLWVGQCVALYLVGALEWVIVGFSKWDNECQRALDRLDDTSSDSEGEEAVRTTGSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCM6</accession>
    <name>E3QCM6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Isochorismatase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_03758</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092634.1">
        <property type="nucleotide sequence ID" value="XM_008094443.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCM6"/>
    <dbReference type="STRING" id="645133.E3QCM6"/>
    <dbReference type="GeneID" id="24409123"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03758"/>
    <dbReference type="eggNOG" id="KOG4044">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066901_0_0_1"/>
    <dbReference type="OrthoDB" id="269496at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050993">
        <property type="entry name" value="Isochorismatase_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14119">
        <property type="entry name" value="HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14119:SF3">
        <property type="entry name" value="ISOCHORISMATASE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase-like" evidence="2">
        <location>
            <begin position="10"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ28614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="198" mass="21964" checksum="80BCB0B8363FD3CE" modified="2011-01-11" version="1">MGLIRDHHSVCDLQDKFRNAIFEFDKVVKTTSKLLRAAETLKIPVYTTTQNRARLGDTVSELAPLLRESDLVRAPVDKTRFSMWVPEIAAQFNGKGMHEFLVVGIESHICVTQTALDLLAAGHRVYVLADGVSSCNREEVPIALARLRHEGVTVTTSESVIYEMMGDAARPEFKSIVGLVKDTSKDTKEALQVLTPKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QD61</accession>
    <name>E3QD61_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Terpene synthase</fullName>
            <ecNumber evidence="4">4.2.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_03977</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the terpene synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.-" evidence="4"/>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092853.1">
        <property type="nucleotide sequence ID" value="XM_008094662.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QD61"/>
    <dbReference type="STRING" id="645133.E3QD61"/>
    <dbReference type="GeneID" id="24409342"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03977"/>
    <dbReference type="eggNOG" id="ENOG502SDMI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042538_3_1_1"/>
    <dbReference type="OrthoDB" id="2861623at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010333">
        <property type="term" value="F:terpene synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034686">
        <property type="entry name" value="Terpene_cyclase-like_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35201:SF4">
        <property type="entry name" value="BETA-PINACENE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35201">
        <property type="entry name" value="TERPENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19086">
        <property type="entry name" value="Terpene_syn_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01020">
        <property type="entry name" value="Terpene_Cyclase_Like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU366034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ28833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="403" mass="46048" checksum="2649DC5DD96D9851" modified="2011-01-11" version="1">MCVDQQLFHSGVRGRADTYKKNAKDTNASKMSPKTQEARVISEALKGQTIHVPNLYSILKGWPVKANVNYERLVPVVEDAFDRQSPNLREKYRRADYARFVSLYYPHPEWDRVQTLALYIIWLFCWDDAIDQQGTVDLSNNLLRAKTRRDNTIRVLEYVLGLAPKFGSDTQFSQADYELKVIGDELKKAYTQEQRQVFMSQMRRYIGNCHEEQTMRLQGTLPSIESYSELRHGTAAVWTLCALVESVIQEIRYSSLVDQYIRFGLSENISEHIRYMEQIQTIWSETSRAVWITNDILSLRKEIPKEGSESVVNAIPIIMKHEGKCPQQAVDALLAELATSVAAFEAAAIGLEEAADKGERELLKTYCDACRCMVTGSILFSLESSRYKLEDCLNEDGSLDILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QD64</accession>
    <name>E3QD64_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_03980</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
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            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_008094665.1"/>
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    <dbReference type="STRING" id="645133.E3QD64"/>
    <dbReference type="GeneID" id="24409345"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03980"/>
    <dbReference type="eggNOG" id="ENOG502S92A">
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="90"/>
            <end position="318"/>
        </location>
    </feature>
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        </location>
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        </location>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
    <sequence length="318" mass="34548" checksum="A52C94EE8F97EF01" modified="2011-01-11" version="1">MGQFFVSWELWQQMTFILACAIGVVFVIGFIKLWWMNRYIARQEIIDAEKRAHAAELASTGLPVPPRKKSEVPFGVRAIQSGIEVDGIWISRPNTPSSEPSPNSARAKGKYVSMGPISPRSSVSDTFSSSSRAEIGPQTYRPKSTYNPGTSRADALSQLEGKPQESFAYNTYHPRSSNPISEASDESGSSLSPVDRSPYNGAGVHMPAHAPPVNRHLKNARNAKENNSQPRTGNGVRANKGNLQPPKDNKGYSGLPQASPLSEFSDPFADPQQPTDTFSDDHAILPSSPHVKFAANDHIARQRSYSGSSSGSSSVRHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QD94</accession>
    <name>E3QD94_COLGM</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">GLRG_04010</name>
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        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
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        <lineage>
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            <taxon>Fungi</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
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        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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    <dbReference type="OrthoDB" id="4846438at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        </location>
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        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EFQ28866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="647" mass="71445" checksum="71F20DB6FAA44200" modified="2011-01-11" version="1">MTPFKATQPLKVGDLNLAKPFSSNDHRALAQEVGRLIKIRGDMGNKMTESMKHLNQSKDVQLQQELLLQIKVLADRKKLFELDPSDARARDVEILKSLLSKLHDENQTPKRGHKDKSFGCGAGGASSVDWDYKMSGPGRDNDDYRAALEKDLSMGPTFSITASSTKKRKRADETARTFKEAENGVSTVDHGQNSQEDINMNMEKSAKKNKIKQKAISISSFDAESMEDGSNQGADACLTDSKASKAHDGLVNVEINYGYDDEAKKDKAKKNKKLSKPPKSKCSFVVETEHETDDNSKKPTGQVSKAEKHNSGAADDVKEYTKAKKEAKMKKQKKRKKHRVVTTATGSDNVVVIDADQQRGLGELETCSGDHSNLELDALKGVEKENQTTDDTVVNTKQKCSELRKRIQVTDSEQSAANEGNKTWRRNRAMASETNSRVFYAGQEKAEDAGSYGSEAAFSTTKRALKGPTRIRPPVIPVPSFFETAGRTPLNPWSAYRRASIEHIEKAEKPQDDQVWVLGTTGSRKKGGLEDSDTKIFTKTIGKVDAPTKVDQSSPTPLPKKDQKKKTRLSRKVKKPVVPLDSLPEIAQGKTSVPGVRVSEDLVRLITPYAALLGSVERAESLNKLLAKPGVAQRREEDLVQDRWSPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDA9</accession>
    <name>E3QDA9_COLGM</name>
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        <submittedName>
            <fullName evidence="7">Nuclear fragile X mental retardation-interacting protein 1</fullName>
        </submittedName>
    </protein>
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        <name evidence="7" type="ORF">GLRG_04025</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
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        <lineage>
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            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
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    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
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                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
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            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="NUFIP1_cons_dom"/>
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    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13309:SF0">
        <property type="entry name" value="FMR1-INTERACTING PROTEIN NUFIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13309">
        <property type="entry name" value="NUCLEAR FRAGILE X MENTAL RETARDATION PROTEIN INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="478"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="478"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
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        <location>
            <begin position="381"/>
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        </location>
    </feature>
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        <location>
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    </feature>
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        <location>
            <begin position="63"/>
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        </location>
    </feature>
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    </feature>
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        <location>
            <begin position="149"/>
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        </location>
    </feature>
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        <location>
            <begin position="190"/>
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        </location>
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        <location>
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        </location>
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    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="277"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="301"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="318"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="346"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="396"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="407"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="466"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="550"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="569"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ28881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="642" mass="69668" checksum="BFD0B7EDE13EE915" modified="2011-01-11" version="1">MSGYNYGPPPPPPPAAQASHAGYGHHNTPYQQHPRGGATHASRGGRGGYPSNGRPEYPPAPQPQYEYGRQQQQQYLQHSPGYPAQPLAASNYPHQQQWHQDHAHGTPQHNAPQHGAHAPAPLSTTNYHPNYAPQIYAHPQQPQPPPHQPGYGPQQPQQQPYSQPYAPPAPYSAPQPWAGHDPHAPSQYGAGRGRGGYGNDRGGSRGAHNMSTPAPVAYGSDGGHHQANGAYGQPYVDPRAPPVPYQPPAQYPYHAPPPAPHASVPPREPFYKHDGQAGRGRGGHRGGNPRGRGSFNTNDRGRHRSQGSHNHRQDGGGSHHKHDNAASGKKKKRKTNTLGLTPGQDSESEDDEMEEETLRKLIGADALQVNDIDAYIAERKKRFPTAARVKAKKSAETTQGNGNKISSDLEKEENLASKLRRQLEKVESSIKRKREQQDEGDEMRDSPSIDIKSEDDEPEVASSRVQPPPPPPPPAKKADISKHCKYYSTGGTCGKKGKCRFVHDPAVREAAMKDREANNGHLTIQQRLILNDKDQEDLTVLQSIQYLREKGLMKPEEKPDGSKGHHAGGSHASQSDSRQKSSNLPAAPASLPAPPLKHHNGLPPHKPPPSALSTGSGGSTVRYKGWNLSGYGNSGLKSEDLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDF1</accession>
    <name>E3QDF1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxidoreductase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_04067</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092943.1">
        <property type="nucleotide sequence ID" value="XM_008094752.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDF1"/>
    <dbReference type="STRING" id="645133.E3QDF1"/>
    <dbReference type="GeneID" id="24409432"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04067"/>
    <dbReference type="eggNOG" id="ENOG502QQXH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023194_4_3_1"/>
    <dbReference type="OrthoDB" id="2129491at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051450">
        <property type="entry name" value="Gfo/Idh/MocA_Oxidoreductases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43377">
        <property type="entry name" value="BILIVERDIN REDUCTASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43377:SF12">
        <property type="entry name" value="BINDING ROSSMANN FOLD OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11840)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="2">
        <location>
            <begin position="35"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ28923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="539" mass="58834" checksum="CFA7AEE446779B5E" modified="2011-01-11" version="1">MSSVKKSDSPVAIPHDGQPTPVPPEKPAMSASPPRILIIGAGSRGQAYARATETSSNGIVAAVAEPIAYKRQTFGRTYIWGSDNPQEGQQFSDWTEFIAYETSRREREAAGEDVPPGVDAAFICVLDEMHRDVVVGLAPLGLHVMCEKPLATSLADCLDMFDALKPPAGQEPKNVFSIGHVLRYSPHNMLLRKLLLEDCVIGDIIKIVHTEPVGWWHFTHSYVRGNWRNEKTTAPSLLTKSCHDIDLLLWLLSAPVKAGQGTPHLPSTVSSTGSLQLFRKARKPAAAGNATNCLTCPLGEEGCKYSAKNVYLGPDLHGLGSGNTDWPVSIVLPEIEDFPTALERNKALAAKLAEDYDETTPKDVVASRNWFGRCVFEADNNVCDDQTVTITWDDATTTDSEAPKQAKSATLHMVAHTKKICERYTHIYGVDGEVYADARTITIDDFNTGATQSYHPTIEDAGHGGGDKGLARQFILAVDRVKNHGWTAERAQNEFIGCSLEEVIRSHAMVFAAEEARTAKKVVGWEEWWSGNVTNQGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDF6</accession>
    <name>E3QDF6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Non-histone chromosomal protein 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_04072</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">DNA-binding protein that induces severe bending of DNA. Required for DNA-binding by the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. Also augments the fidelity of transcription by RNA polymerase III independently of any role in the FACT complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NHP6 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092948.1">
        <property type="nucleotide sequence ID" value="XM_008094757.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDF6"/>
    <dbReference type="STRING" id="645133.E3QDF6"/>
    <dbReference type="GeneID" id="24409437"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04072"/>
    <dbReference type="eggNOG" id="KOG0381">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082854_10_1_1"/>
    <dbReference type="OrthoDB" id="1919336at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01390">
        <property type="entry name" value="HMG-box_NHP6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.30.10:FF:000016">
        <property type="entry name" value="FACT complex subunit SSRP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050342">
        <property type="entry name" value="HMGB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN DSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112:SF22">
        <property type="entry name" value="MITOCHONDRIAL TRANSCRIPTION FACTOR A, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00886">
        <property type="entry name" value="HIGHMOBLTY12"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="8">
        <location>
            <begin position="26"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="6">
        <location>
            <begin position="26"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="72"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00043963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00057588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00067275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ28928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="103" mass="11679" checksum="2032312CC9DC1E87" modified="2011-01-11" version="1">MPKASTKRGAAGKVDKKRAKKDPNAPKRGLSAYMFFANEQRENVREENPGISFGQVGKILGERWKALNDKQRAPYEAKAATDKKRYEDEKQAYNAEQEEDESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDG7</accession>
    <name>E3QDG7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aldo-keto reductase ausK</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_04083</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis; terpenoid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092959.1">
        <property type="nucleotide sequence ID" value="XM_008094768.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDG7"/>
    <dbReference type="STRING" id="645133.E3QDG7"/>
    <dbReference type="GeneID" id="24409448"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04083"/>
    <dbReference type="eggNOG" id="KOG1575">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_2_1"/>
    <dbReference type="OrthoDB" id="48988at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000024">
        <property type="entry name" value="Aryl-alcohol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF2">
        <property type="entry name" value="ARYL-ALCOHOL DEHYDROGENASE AAD10-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="5">
        <location>
            <begin position="34"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00073126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ28939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="386" mass="43238" checksum="B75E2B4354A20B79" modified="2011-01-11" version="1">MSAIKNVFAPAPEPKTELGRYRVLSTTAGVRVSPLCLGAMSIGSAWSSFLGSMEKDQSYKLLDAFVEAGGNFIDTANNYQNEESEQILGEWMAARRNRDIMFVATKFTTQYRKHELGPGKCINYSGNHKKSLHLSVRDSLRKLQTDYIDLLYVHWWDWTTSIEELMDSLHILVEQGKVLYLGVSDTPAWIVSAANTYAKAQGKTPFSVYQGRWNVLIRDVERDIIPMARHFGMALCPWDVLGGGKLQSMTQLEARQKAGEGLRCTFGPNQSDEERKASEVLEQIAKEHGTESIQQIALAYVMQKARYVFPVVGGRKVENLEDNIKALSICLTEEQIQTIESIKKFHIGFPMDFILDDPREGGPTAPLVAASAPMDWQLQGKPIGQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDX1</accession>
    <name>E3QDX1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Beta-ketoacyl synthase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_04203</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093079.1">
        <property type="nucleotide sequence ID" value="XM_008094888.1"/>
    </dbReference>
    <dbReference type="SMR" id="E3QDX1"/>
    <dbReference type="STRING" id="645133.E3QDX1"/>
    <dbReference type="GeneID" id="24409568"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04203"/>
    <dbReference type="eggNOG" id="KOG1202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_6_0_1"/>
    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.366.10:FF:000002">
        <property type="entry name" value="Probable polyketide synthase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.10:FF:000011">
        <property type="entry name" value="Sterigmatocystin biosynthesis polyketide synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.129.110:FF:000001">
        <property type="entry name" value="Sterigmatocystin biosynthesis polyketide synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030918">
        <property type="entry name" value="PT_fungal_PKS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032088">
        <property type="entry name" value="SAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04532">
        <property type="entry name" value="PT_fungal_PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF37">
        <property type="entry name" value="SI:DKEY-61P9.11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22621">
        <property type="entry name" value="CurL-like_PKS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16073">
        <property type="entry name" value="SAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01294">
        <property type="entry name" value="PKS_PP_betabranch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="8">
        <location>
            <begin position="381"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="9">
        <location>
            <begin position="1298"/>
            <end position="1605"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="1664"/>
            <end position="1738"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="1786"/>
            <end position="1863"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="5">
        <location>
            <begin position="1298"/>
            <end position="1429"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="5">
        <location>
            <begin position="1457"/>
            <end position="1605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1617"/>
            <end position="1647"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1744"/>
            <end position="1788"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1863"/>
            <end position="1908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1617"/>
            <end position="1634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1635"/>
            <end position="1646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1747"/>
            <end position="1759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1880"/>
            <end position="1892"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="5">
        <location>
            <position position="1330"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="5">
        <location>
            <position position="1517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ29059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="2178" mass="236942" checksum="FAFB43039C3231F6" modified="2011-01-11" version="1">MADMMSYLLFGDQSLDTHGFLAEFCRSGNPSTLAKEFLDQAGQALREEVDGLGKLERSKLPNFQSLRQLNERYHAQGIKHPGIDSALLCITQLAHYIDRTEKEPQDDAPHDHTFFMGLCTGLFAAAAIASTPSVSTLIPVAVQVVLMAFRTGTHVGSLAERLSPPVGQSEPWTHILPGLKESNAKEALNTFHESNYIPVASQAYVSAVSASSLAISGPPATLRALEDQNVFGVKPTAIPVYGPYHAAHLHGTADIEKILRLDDPKVLEVFAKSKPRSAIMSGTKGIWFAEDDTKSLLKAVAHECLVDVLHFQKGIEGCIETARDFEGSTCLVIPFGPTYNAETLSKLIQDRTKLNVQVRHGPKIQRESINSPIGNHGSSGKCKLAIVGMAGRFPDAASHEKLWELLSKGLDVHRVVPPDRFPVATHYDITGKAINTSHSQYGCWIENPGYFDPRFFNMSPREAFQTDPMQRMALTTAYEALEMCGYVPNRTPSTKLDRIGTFYGQTSDDWREINAAQEVDTYYITGGVRAFGPGRINYHFGFSGPSLNIDTACSSSAAALNVACNALWVKDCDTAIVGGLSCMTNPDIFAGLSRGQFLSKTGPCATFDNGADGYCRADGCASVIVKRLDDAIADKDNVLAVILGTATNHSADAISITHPHGPTQSILSRHILDEAGVDPLDVDYVEMHGTGTQAGDGTEMVSVTNVFAPADRKRPADRPLYLGAVKSNVGHGEAASGVTALTKVLMMMQKNAIPPHVGIKKEINKTFPKDLSERNVNIAFHLTPFKRRDGKPRRIFVNNFSAAGGNTGLLLEDAPHVKASETDPRNVQVVTVTGKSKAAMIRNAERLVGWMEQNPQTPLSHLAYTTTARRIQHYWRMNVAASDLPEAQRLIKDRLKENFTPISTQQPKVVFMFTGQGSHYAGLGKDLYAHYTVFRENINEFNQLAQIHGFPSFLPLIDGSESDVTKFSPVVVQLGLCCFEMALARLWSSWGIKPSAVMGHSLGEYAALNAAGVLSASDTIYLVGARAKLLVEKCTAGTHAMLAVTGPVDAVMEALGAQSEHVNVACINGPRETVLSGAAAKISDISSHLGTAGFKCTQLKVPFAFHSAQVDPILDDFETLARSVSFERPQVPIISPLLGKMLESEPINAAYLRNHARDAVNILGGLVHAQQSGAVDEKTVWLEVGPHPVLANFVKSSFGISSVAVPTLRRNESTYKVLSNTLCALHTAGINLDWDEFHRDFTECTRLLDLPTYSFDEKNYWLQYTGDWCLTKNRGPSAVKAPLQIEPARPKLCTTSIHGVTNEDVNGDIALVETETNLSRPDTRPLVEGHLCNGAPLCPSTLYADMAMTVADYAYKMLRPDAEPVGLNVANVEVPKTLIFDDKLDAHILRTTVTANAALGYADVSFHTGEGSKKTEHAHCKVVYGSTEQWADEFERVSYLIKGRIDALEEAERQGKASKIGRGLTYKLFTALVDYDTKYQGMEEVILDSKACEATAKVSFQTTDKDGNFFFNPYWIDSCCHISGFIINGTDAIDSREQVFISHGWGSLRFTEKLDASKTYRSYVRMQPVKGTKMMAGDAYVFDGDRIVGVAGDVKFQSIPRKVLNMVLPPRGRAAAGATSAAPAPKAAAPSKAAPAKEKSGKEKVSKQVTASNLKAVNAKLAKRSVVQDVFDILAKEVGVTQDELADNIAFTDLGCDSLMALTVSGRMREELDIDIDSHAFVEYPTIGAFKVFLSQFETAGGKDSYVQDSGDSSASVSETPELESDSNVTTPYEESDRSVKGDADEEGCDLQSVLRETIATEMGVEVDEIVAAPDLAALGMDSLMSLSILGTLREKSGMDIPSDLFVTNPSLLEVEKALGIGPKPKPAPAAKPAKVASAPRREKVEPTREINTHPGNTTASITKPPPPREIVDNYPHRKATSILLQGSTRTATKNLWMVPDGSGCATSYTEISQISSQWAVWGLFSPFMKTPDEYKCGVYGMATKFIEAMKARQPKGPYSLAGWSAGGVIAYEIVNQLTKAGESVENLIIIDAPCPITIEPLPKSLHAWFASIGLLGEGDDDAKKIPSWLLPHFAASVTALSNYTAEPIPKEKCPNVMAIWCEDGVCHLPSDPRPDPYPTGHALFLLDNRTDFGPNRWDEYLDINKFRTRHMPGNHFSMMHGDYAKQLGQFIREAVCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEN1</accession>
    <name>E3QEN1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04481</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093357.1">
        <property type="nucleotide sequence ID" value="XM_008095166.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEN1"/>
    <dbReference type="GeneID" id="24409846"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04481"/>
    <dbReference type="HOGENOM" id="CLU_3014064_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="56" mass="5717" checksum="CBE0C9AFD35B43D0" modified="2011-01-11" version="1">MGLLRPTSSAPDGCLAPRPGGADPSGRTRVGSSRGNGALWVRLKGPGGRGRRLFDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEQ7</accession>
    <name>E3QEQ7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pre-mRNA-processing factor 39</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_04507</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the PRP39 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093383.1">
        <property type="nucleotide sequence ID" value="XM_008095192.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEQ7"/>
    <dbReference type="STRING" id="645133.E3QEQ7"/>
    <dbReference type="GeneID" id="24409872"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04507"/>
    <dbReference type="eggNOG" id="KOG1258">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007434_3_1_1"/>
    <dbReference type="OrthoDB" id="10265668at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000243">
        <property type="term" value="C:commitment complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030627">
        <property type="term" value="F:pre-mRNA 5'-splice site binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000395">
        <property type="term" value="P:mRNA 5'-splice site recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140727">
        <property type="term" value="P:siRNA-mediated pericentric heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000451">
        <property type="entry name" value="mRNA splicing protein (Prp39), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000064">
        <property type="entry name" value="Putative pre-mrna-processing factor 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059164">
        <property type="entry name" value="HAT_PRP39_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17204">
        <property type="entry name" value="PRE-MRNA PROCESSING PROTEIN PRP39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17204:SF5">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23241">
        <property type="entry name" value="HAT_PRP39_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23240">
        <property type="entry name" value="HAT_PRP39_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ29363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="590" mass="69058" checksum="2F08D8D742FFB8FF" modified="2011-01-11" version="1">MSDYDHFGSSEEESAEIKKLQADVDADPDNFETWEKLIRACEGLEGGLNRNSSPQALATLRDAYDRFLLKFPLLFGYWKKYADLEFNIAGPESAEMVYERGCASITNSVDLWTDYCSFKMETTHVPHLVRELFERGATCVGLDFLAHPFWDKYIEYEERQEAQDKIFAILSRVIHIPMHQYARYFERFRQLSHSRPVTELVPAETLAKFKAEVEAESAQFAGVQRTELEIERDVRTKIDAMYYEYFTQTQAETNKRWTYESEMKRPYFHVTELESSQLANWRKYLDFEESEGNFTRIVFLYERCLVTCAFYDEFWFRYARWMSAQEGKEEEVRIIYQRASTLYVPISRPGIRLQFAYFEESCGRVDIARDIHAAILMKLPDCIEVITSWAHLQRRQSGLDAAIEVFKAQIDSPHVDIFTKAALVTEWALFLWRVKGSVEEARNVFLKNVQWYADSRVFWNKWLEFELQQATSTEVEDQHGDRVKQIFDELRTKSRLSASTKKELYQIYLSYLQQRGGKDAMKQFLTVDREIFGPSSISLLNKATANGKENGIAGAEMDEATRYRAEARYLRYYEIQGEPDLEGQATAPFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEX8</accession>
    <name>E3QEX8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DUF1907 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_04578</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093454.1">
        <property type="nucleotide sequence ID" value="XM_008095263.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEX8"/>
    <dbReference type="GeneID" id="24409943"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04578"/>
    <dbReference type="eggNOG" id="KOG4048">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055541_0_0_1"/>
    <dbReference type="OrthoDB" id="5119241at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17298">
        <property type="entry name" value="DUF1907"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015021">
        <property type="entry name" value="C11orf54_DUF1907"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13204:SF1">
        <property type="entry name" value="ESTER HYDROLASE C11ORF54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13204">
        <property type="entry name" value="PTD012 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08925">
        <property type="entry name" value="DUF1907"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01168">
        <property type="entry name" value="DUF1907"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117856">
        <property type="entry name" value="AF0104/ALDC/Ptd012-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="DUF1907" evidence="7">
        <location>
            <begin position="19"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ29434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="318" mass="34718" checksum="C96DC4E914CF5CCA" modified="2011-01-11" version="1">MRVEKFPLSPPSLEELAERLRAPLAANYEHASVSVVRCTDLRKPPFHLAGEGLSGDEKIADVGGQPNLFPRPRLDTIWSIPDLGRHMEMSPEKGSLIGAGAGPFHVIGQNTELAPNLSWSGGIDNVDNQSRVIKIERGTEAVRVDTSPSVDCGLMVNLYGSLGEPGPVLKITAKGRKGPEKSFTECIRKGLHVAYGNDRTISLGGAFVVKAGKATYHIMPDFPPEEDLPFKNRKEVEKWLTFHDFDSPIVGLSVLNSADPDNKMGLRIEHTHAFSPSGKNAGGHYHYEAEGEEKTIEYEGYFNTAKTIYRIDSPTASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEY2</accession>
    <name>E3QEY2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04582</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093458.1">
        <property type="nucleotide sequence ID" value="XM_008095267.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEY2"/>
    <dbReference type="GeneID" id="24409947"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04582"/>
    <dbReference type="eggNOG" id="ENOG502T4PF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2739898_0_0_1"/>
    <dbReference type="OrthoDB" id="4791085at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180368" evidence="1">
        <location>
            <begin position="18"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="64" mass="6782" checksum="F9DD942272233BB3" modified="2011-01-11" version="1">MQFSAIIVALFAGIALAAPALEARQDSTECTLCRNDCFFSKTDNAAFQSCIQSCNSGLGCNITQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEY6</accession>
    <name>E3QEY6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_04351</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093227.1">
        <property type="nucleotide sequence ID" value="XM_008095036.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEY6"/>
    <dbReference type="GeneID" id="24409716"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04351"/>
    <dbReference type="eggNOG" id="ENOG502S8TX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_119592_1_0_1"/>
    <dbReference type="OrthoDB" id="3344950at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ29207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="145" mass="16494" checksum="A41869AFD4252E6C" modified="2011-01-11" version="1">MATAETVDLGEVHEPREESIKVFREIEHDLKKELLHIRREYQKHEPEYFQAVAHLDDHALAAFGPDDLVAIRVAVSAYGIHLFGKIRIPALPDSGPAYIHFRAFVPGGEPPKLHSIHTEEKEHSDGDKTYRAIFTKGDALEWFDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFJ3</accession>
    <name>E3QFJ3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04775</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093651.1">
        <property type="nucleotide sequence ID" value="XM_008095460.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFJ3"/>
    <dbReference type="STRING" id="645133.E3QFJ3"/>
    <dbReference type="GeneID" id="24410140"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04775"/>
    <dbReference type="eggNOG" id="ENOG502S8KX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092849_2_0_1"/>
    <dbReference type="OrthoDB" id="2400485at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34213">
        <property type="entry name" value="NUCLEAR TRANSPORT FACTOR 2 (NTF2) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34213:SF2">
        <property type="entry name" value="NUCLEAR TRANSPORT FACTOR 2 (NTF2) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="227" mass="24867" checksum="1422D9B4DD8A2DC1" modified="2011-01-11" version="1">MHSSARHIAKQIATHPETKSIAKQVQRNMASGTPSETAKAQASADANAPSFESIGIKNNDIVQKSGVSLSQQQKVLVGSVLDLFEGNPTLKHLSLWSRNATFQDNITVAEGYDKFAAQWYGLPALFNPIKIQSHTVTSAGNPIELELKNSYTVKGVKTEQTMESVVQIEVGDDGKIVKVNDKWNNNLPDGAFSQALRKLNAVTVPAFVKVPKNEEEDQKLKAEREKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFM5</accession>
    <name>E3QFM5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl hydrolase family 16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_04807</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093683.1">
        <property type="nucleotide sequence ID" value="XM_008095492.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFM5"/>
    <dbReference type="STRING" id="645133.E3QFM5"/>
    <dbReference type="GeneID" id="24410172"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04807"/>
    <dbReference type="eggNOG" id="ENOG502SJND">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019533_3_0_1"/>
    <dbReference type="OrthoDB" id="192832at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02182">
        <property type="entry name" value="GH16_Strep_laminarinase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF60">
        <property type="entry name" value="GRAM-NEGATIVE BACTERIA-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180378" evidence="1">
        <location>
            <begin position="20"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="2">
        <location>
            <begin position="33"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ29663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="295" mass="31864" checksum="8668624608C33F1C" modified="2011-01-11" version="1">MVFNKVVSALAFGLPAVQAVVPSIPGFSLTWSDDFVGSPNSLPNTGSWLFDDGTSYPGASANWGTGEIQTYTSSTNNIRLDGNGNLQIIAIRDGAGAWTSSRIESQRGDFMALAGGKMRIQASLNLPDLGPNGVGYWPAFWSLGTEFRGNYWNWPGIGEWDIMENVNGVDRVWGTMHCGQTPGGPCQETNGLGQFRECPGSPCQGNFHTYTLEVDRTQGLEAVRWFVDGILYWQIVETDLPDDVWARAVHSPHFILLNLAIGGSFPNGVYGGNTPLPTTASGGVFQVEYVAVYNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGI2</accession>
    <name>E3QGI2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribonuclease</fullName>
            <ecNumber evidence="9">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_05114</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 9">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase HII family. Eukaryotic subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="9"/>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ29970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093990.1">
        <property type="nucleotide sequence ID" value="XM_008095799.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGI2"/>
    <dbReference type="STRING" id="645133.E3QGI2"/>
    <dbReference type="GeneID" id="24410479"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05114"/>
    <dbReference type="eggNOG" id="KOG2299">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036532_0_0_1"/>
    <dbReference type="OrthoDB" id="7462577at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032299">
        <property type="term" value="C:ribonuclease H2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043137">
        <property type="term" value="P:DNA replication, removal of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07181">
        <property type="entry name" value="RNase_HII_eukaryota_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.460:FF:000001">
        <property type="entry name" value="Ribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000016">
        <property type="entry name" value="Ribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.460">
        <property type="entry name" value="Ribonuclease hii. Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004649">
        <property type="entry name" value="RNase_H2_suA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001352">
        <property type="entry name" value="RNase_HII/HIII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024567">
        <property type="entry name" value="RNase_HII/HIII_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023160">
        <property type="entry name" value="RNase_HII_hlx-loop-hlx_cap_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00729">
        <property type="entry name" value="ribonuclease HII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954">
        <property type="entry name" value="RIBONUCLEASE H2 SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954:SF7">
        <property type="entry name" value="RIBONUCLEASE H2 SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01351">
        <property type="entry name" value="RNase_HII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51975">
        <property type="entry name" value="RNASE_H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 9" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7 8 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8 9" id="KW-0540">Nuclease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-2" evidence="10">
        <location>
            <begin position="66"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ29970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="344" mass="36824" checksum="396EC57E6335E250" modified="2011-01-11" version="1">MEDSQMAEDIALETPVADVFIPPSINDKAILSGDSYTYFSLVPSTLLPPSSSPTKTASESPASGTPVCLGVDEAGRGPVLGPMVYGVFYLPIPLSDPLLRETHHFDDSKVLTPAVRSQLMAALCTAGSDLAESCGFAISALSARDISSGMMRPGANYNLNAQAMDATVELIKGVFAQGVNIQEIYVDTVGQPAAYQAKLQRFFPATKITVAKKADSLYPCVSAASVCAKVTRDAALEVLYKARAPESVVEEGMAWGSGYPSDGRCVSWMKSNMHPVFGWGPECRFSWGTAKDMLEGKGGLKVDWPVEDDDDTARMTDFFISGDREQDGDELGTWFGRPAGLEAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGL9</accession>
    <name>E3QGL9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Myb-like DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_05151</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ30007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094027.1">
        <property type="nucleotide sequence ID" value="XM_008095836.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGL9"/>
    <dbReference type="STRING" id="645133.E3QGL9"/>
    <dbReference type="GeneID" id="24410516"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05151"/>
    <dbReference type="eggNOG" id="ENOG502SFTJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092483_0_0_1"/>
    <dbReference type="OrthoDB" id="5353914at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054505">
        <property type="entry name" value="Myb_DNA-bind_8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22980">
        <property type="entry name" value="Myb_DNA-bind_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb-like DNA-binding" evidence="2">
        <location>
            <begin position="16"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ30007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="183" mass="19368" checksum="377A098DD81810F0" modified="2011-01-11" version="1">MASVGTDAEGSVKFLVDFQAVADDCSIVSKAAAAKRFERLLKAHGLKASELSKGGPMSGASSPAQSTASPKTPAKGTGKATPKSKGKRAAQASPTKDTKRAKMANHPAVTSYNDEDEEEDEAQFKVKEETQATGEASTNHGSYCDYSRGRDDDDDELQLLYIVEKPTGCPVHDSGEFRAPPSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QH89</accession>
    <name>E3QH89_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">beta-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_05395</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="3"/>
    <dbReference type="EMBL" id="GG697348">
        <property type="protein sequence ID" value="EFQ30251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094271.1">
        <property type="nucleotide sequence ID" value="XM_008096080.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QH89"/>
    <dbReference type="STRING" id="645133.E3QH89"/>
    <dbReference type="GeneID" id="24410760"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05395"/>
    <dbReference type="eggNOG" id="ENOG502QQ55">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004542_5_1_1"/>
    <dbReference type="OrthoDB" id="2123594at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000495">
        <property type="entry name" value="Periplasmic beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1700:FF:000009">
        <property type="entry name" value="Periplasmic beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051915">
        <property type="entry name" value="Cellulose_Degrad_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30620:SF117">
        <property type="entry name" value="BETA-1,4-XYLOSIDASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30620">
        <property type="entry name" value="PERIPLASMIC BETA-GLUCOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180412" description="beta-glucosidase" evidence="9">
        <location>
            <begin position="19"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type III-like" evidence="10">
        <location>
            <begin position="696"/>
            <end position="765"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ30251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="777" mass="84276" checksum="5F17CF948B9E02CB" modified="2011-01-11" version="1">MKLSLTFASSLLVAAVAAQNGTYTNGTGTPVYKNPNATIDDRVSDLLKRMTIEEKTAQLIQGDITNYLNLTDGTFNQSGLTWLAEKRSSSIWTGLYTNLTTLAYGARVAQDYLVHNTTLGIPAFIQSEGIHGFLALNATIFNSPIAHGCSWNPQLVEKMARIIAIESKALGVNQLFAPNVDLARELRFGRVEECYGEDPFLVGEYGYSYTKGLQEEGVCAMIKHFAAFATPEQGVNTAPVHGGPRELHTTYLPPFKRAIIDADAWSVMSSYNSYDGVPTVTDHHLLTEILREEWGYEYYVISDAGGTARVSSAFLICGETDDSCITLSTLPAGNDAEMGGGRYSFQYVPELVANGTLPENIVDTAVSRVLRAKFKSGLFEHPYTGVPNDKFFDYVNTEEHRKVARDLDAESIVLLENHNETLPLKKDAHVAVIGPMAHGYVNYGDYVIHTAMERGVTPFDGIRAASEGIVTYAKGGERWSNDQSGFPEAIAAAEAADVAVVVVGTWSRDQNELWAGLNATTGEHIDVHDFKLVGAMSHLVKAIIDTGKPTVVVFSSGKPVTEPWISDEAGALVQMFYQGEEGGHALADILYGNVNPSGKLSVAFPHDVGTTPVYYDYLNSARASPNPGKEYPNGTLVFGSNYVLSSPLPLYEFGYGLSYSNFNYADISVSSSTVSPTDTVTLNVKVTNNSTRDGAEVVQVYIKDMISSVAVPNKQLRGFSKVFIKAGETANVSIDLPVSGWGLWNRKLQYVVETGDFTVLVGSSSDDIRGNATVTVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHZ6</accession>
    <name>E3QHZ6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein SDS23</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Protein sds23</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_05628</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Involved in DNA replication and cell separation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the SDS23 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697349">
        <property type="protein sequence ID" value="EFQ30484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094504.1">
        <property type="nucleotide sequence ID" value="XM_008096313.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHZ6"/>
    <dbReference type="STRING" id="645133.E3QHZ6"/>
    <dbReference type="GeneID" id="24410993"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05628"/>
    <dbReference type="eggNOG" id="KOG1764">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024459_0_0_1"/>
    <dbReference type="OrthoDB" id="449052at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004865">
        <property type="term" value="F:protein serine/threonine phosphatase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042149">
        <property type="term" value="P:cellular response to glucose starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030071">
        <property type="term" value="P:regulation of mitotic metaphase/anaphase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02205">
        <property type="entry name" value="CBS_pair_SF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050511">
        <property type="entry name" value="AMPK_gamma/SDS23_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016711">
        <property type="entry name" value="Ssd23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780">
        <property type="entry name" value="AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780:SF36">
        <property type="entry name" value="CBS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018148">
        <property type="entry name" value="UCP018148_CBS_YBR214w"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CBS" evidence="12">
        <location>
            <begin position="194"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="12">
        <location>
            <begin position="268"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="452"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="471"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR018148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ30484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="490" mass="52812" checksum="184D7FFE69B59E5B" modified="2011-01-11" version="1">MDATAASGSHNDEAIATSPPALPQRTPSQTSLHKATHVHAHRQSFAENLRNAPGSPRAQRHPSFTQAAVQELLNHPPAANKHADPRFAGRDWRDISVNELVAQDDFKWATLDTSVEEASMTLVKHSPSNVVLIRQDDSAKTAISTFDYNDLNTYLLIVVGLAKPDEEQVPLYDEIVNKARNGARIALRDIQPLCRKESLIALPFDETLERAIEVFGSGIHRVLVTNPTGDVIGILSQLKAIEFFWNEGINFPAIDRLYPVTLRDLGIGTQQIVAVNSDSPLGDALALMNAEGLTSVAVIDNGHNVVGNISTVDVKHLVNAADAPLLKSSCMHFISVILSERGVEHGRDSFPVFYVNPYSTLAHTVAKLVATQSHRMWVVESASPSPSAPATPLLAPTTSNVLVPGPGSAPQSPLPTQTHTAVPAAAMPGAHLSGRLTAVVSLTDILNMFAKSSGLRPTDPGEQRARRRRSSSSSVRPSLDSSRPSIDLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QI08</accession>
    <name>E3QI08_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Zinc finger containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_05640</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the ZNF593/BUD20 C2H2-type zinc-finger protein family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697349">
        <property type="protein sequence ID" value="EFQ30496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094516.1">
        <property type="nucleotide sequence ID" value="XM_008096325.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QI08"/>
    <dbReference type="STRING" id="645133.E3QI08"/>
    <dbReference type="GeneID" id="24411005"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05640"/>
    <dbReference type="eggNOG" id="KOG3408">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_117291_2_2_1"/>
    <dbReference type="OrthoDB" id="24683at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043021">
        <property type="term" value="F:ribonucleoprotein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000299">
        <property type="entry name" value="Zinc finger protein 593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051879">
        <property type="entry name" value="C2H2-ZF_Maturation_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46095">
        <property type="entry name" value="ZINC FINGER PROTEIN 593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46095:SF1">
        <property type="entry name" value="ZINC FINGER PROTEIN 593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="50"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="96"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="70"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="80"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="99"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ30496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="121" mass="13954" checksum="F71A467C02889F26" modified="2011-01-11" version="1">MGVTNKKTLTKTRRKTRDVDQIKADMRSPRHLQLYKNTKAKEDLPGLGQHYCVECAKWFETEVSLVGHHRGKPHKRRVKQLKEEPYTQKDAEAAVGLRTDNRGVNKDGPEKALDQEIDMET</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIU0</accession>
    <name>E3QIU0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Amine oxidase</fullName>
            <ecNumber evidence="6">1.4.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_05922</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a secondary aliphatic amine + O2 + H2O = a primary amine + an aldehyde + H2O2</text>
            <dbReference type="Rhea" id="RHEA:26414"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:58855"/>
            <dbReference type="ChEBI" id="CHEBI:65296"/>
            <dbReference type="EC" id="1.4.3.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the flavin monoamine oxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.-" evidence="6"/>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094798.1">
        <property type="nucleotide sequence ID" value="XM_008096607.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIU0"/>
    <dbReference type="STRING" id="645133.E3QIU0"/>
    <dbReference type="GeneID" id="24411287"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05922"/>
    <dbReference type="eggNOG" id="KOG0029">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004498_0_3_1"/>
    <dbReference type="OrthoDB" id="5046242at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097621">
        <property type="term" value="F:monoamine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="entry name" value="RutC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001613">
        <property type="entry name" value="Flavin_amine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050703">
        <property type="entry name" value="Flavin_MAO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43563">
        <property type="entry name" value="AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43563:SF14">
        <property type="entry name" value="AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00757">
        <property type="entry name" value="AMINEOXDASEF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="YjgF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0274">FAD</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="7">
        <location>
            <begin position="157"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="177"/>
            <end position="178"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="380"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="491"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="578"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601613-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ30778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="614" mass="66123" checksum="E1C76847A9EACDCF" modified="2011-01-11" version="1">MPPKVRALDLDNTSTAYYASATVAPSGARLVHVSGQPGNTKDDVVPDDYESQIHLALLNLRKIIIVAGASVKDIVKLTLLIVDYDSSARKHTRHIQRFLGGHRPAITLIPVSKLAVSSWLFEIDAVLAVPETPAPARGLALPDADESVDVVIIGAGLAGLSAARDVLKSGLSCVVLEARDRVGGKTWSEPLQDGQPGVVDLGAAWINDTNQSRVYALAKEYGAELIEQNTNGDVVLQDFDGKCSPFPYGELPFFDEATRKALAGIRDMVEADCQAVDTWKPKDTSLDSLTFAAYLRLRGADDVAMATANVWTCAMLGQEATDISALYFLNYCKSGGGLLQMRSDRKDGGQYLRVRQGTQVFSKGLASSLPEGVVRLSRPVRAVVRDDHPGGGRYAVKVQTDEGVLAARKVITTIPGPALKNISFRPALPLPKQAWIESLSYGYYTKAMMQFESPFWVERGFCGLAQSFVGPASVIRDTSVPADSKHVLTCFMAGDRGRAWAALDAPAREKSLLAQLAQLFGCEDIQSRFVRMSTYEWVKDEWSGWGCPCTSLAPGVLDTLGGDSLRKSCGDLHFAGTETAGEWKGYMEGAVRSGERAAAEVIEALTSTSGASRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJ18</accession>
    <name>E3QJ18_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_06000</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the amidase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094876.1">
        <property type="nucleotide sequence ID" value="XM_008096685.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJ18"/>
    <dbReference type="STRING" id="645133.E3QJ18"/>
    <dbReference type="GeneID" id="24411365"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06000"/>
    <dbReference type="eggNOG" id="KOG1212">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009600_9_2_1"/>
    <dbReference type="OrthoDB" id="6428749at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072:SF11">
        <property type="entry name" value="AMIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072">
        <property type="entry name" value="AMIDASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001221">
        <property type="entry name" value="Amidase_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="5">
        <location>
            <begin position="81"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="212"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="3">
        <location>
            <position position="236"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="233"/>
            <end position="236"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ30856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="536" mass="58206" checksum="41883F83BAECF0D5" modified="2011-01-11" version="1">MGSLKAETWELAAAKKRESLVASFPPEWLVPEDLLPPASQADVTAWPKTSGWFTEAELAITESTAAELIQKLASGQLKSLEVTKAFCKRAVAAHQLTKCLSETCFDRALATARARDEHFERTGQPVGPFHGLPISLKDNFNLKGLDATVGFASHIGNPAEYDASLAALLEDAGAVFYVKTNVPTAMMIAESVNNVFGRTVNPRNRNLTSGGSSGGESALITMKGSPLGIGTDIGGSLRIPAACTGIFTLRPSFGRFPTLGCRSGMGGQEAVQSVNGPMTRTITDLELYSKAVVGRQTWLHDPRCVPIPWRDVRLPEKLKIAVMWDDGMVRPTPPVARALKQTVEKLRAAGHEVVDWDPRDQEQGLSLLARMFVADGGISIKKELEQTGEPFRPEMKAYEEAEELGTYDMWQMHIERTGFQKRYLDRWNAAGIDAILCPTTPFASVKNGQFRHVGYTGVFNVLDYSCVSFPTGLSADESADVFSDSTGEPLGPDCAAIRAEYGPSAVHGMPISLQLVARRLEEEKAIAMVGHILDII</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJC2</accession>
    <name>E3QJC2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Phytase A</fullName>
            <ecNumber evidence="4">3.1.3.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">Histidine acid phosphatase phyA</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Myo-inositol hexakisphosphate phosphohydrolase A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Myo-inositol-hexaphosphate 3-phosphohydrolase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">GLRG_06104</name>
    </gene>
    <organism evidence="22">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>1D-myo-inositol 1,2,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,5,6-tetrakisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77115"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57798"/>
            <dbReference type="ChEBI" id="CHEBI:195535"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:77116"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>1D-myo-inositol 1,2,5,6-tetrakisphosphate + H2O = 1D-myo-inositol 1,2,6-trisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77119"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:195535"/>
            <dbReference type="ChEBI" id="CHEBI:195537"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:77120"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>1D-myo-inositol 1,2,6-trisphosphate + H2O = 1D-myo-inositol 1,2-bisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77131"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:195537"/>
            <dbReference type="ChEBI" id="CHEBI:195539"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:77132"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>1D-myo-inositol 1,2-bisphosphate + H2O = 1D-myo-inositol 2-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77135"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:84142"/>
            <dbReference type="ChEBI" id="CHEBI:195539"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:77136"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>1D-myo-inositol hexakisphosphate + H2O = 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16989"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57798"/>
            <dbReference type="ChEBI" id="CHEBI:58130"/>
            <dbReference type="EC" id="3.1.3.8"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:16990"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the histidine acid phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.8" evidence="4"/>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ30960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094980.1">
        <property type="nucleotide sequence ID" value="XM_008096789.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJC2"/>
    <dbReference type="STRING" id="645133.E3QJC2"/>
    <dbReference type="GeneID" id="24411469"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06104"/>
    <dbReference type="eggNOG" id="KOG1382">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020880_0_1_1"/>
    <dbReference type="OrthoDB" id="6509975at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016158">
        <property type="term" value="F:inositol hexakisphosphate 3-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07061">
        <property type="entry name" value="HP_HAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1240:FF:000027">
        <property type="entry name" value="3-phytase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033379">
        <property type="entry name" value="Acid_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016274">
        <property type="entry name" value="Histidine_acid_Pase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963:SF24">
        <property type="entry name" value="3-PHYTASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963">
        <property type="entry name" value="MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000894">
        <property type="entry name" value="Acid_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00616">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00778">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 19" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="20" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="20">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179779" description="Phytase A" evidence="20">
        <location>
            <begin position="19"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="18">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="18">
        <location>
            <position position="343"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="19">
        <location>
            <begin position="53"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="19">
        <location>
            <begin position="197"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="19">
        <location>
            <begin position="249"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="19">
        <location>
            <begin position="417"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00041857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00042300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00043670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00043675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00043721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00043748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00043788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00044106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR000894-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR000894-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EFQ30960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="448" mass="48844" checksum="2055B0DBD0BFDE19" modified="2011-01-11" version="1">MASAILVSFALAFGFVRGQAPQGDVEPISQSWGQLSPFFSVPSEISAATPPGCEITFAQVLSRHGARDPTAGKTVKYKALVDRIHANVTSYGKGYEFIKTYNYTLGADQLTSFGQKELVDSGVAFYKRYQALAAVNDPFIRASGQERVVESGLNWTQGFYSSKIADGHTGGGGGIAGAVKIIPETKGFNNTLDHGLCTAFEDGAYSKVGDEAQAPWRDIFTPPITARLNENLVGANLTAADTINFMELCPFNTVVEGTQSQFCNLFTLEEWKSYEYYETLGKYYGYNAGNPLGPTQGVGFTNELIARLTRQPVVDHTSTNSTLDSDPATFPLDKKLYADFSHDNDMMTIYGALGLYNETKPLSKTELTPVSETKGFTASWTVPFAARMYVEKMKCDGTDEEMVRVLVNDRVVPLVGCGADDLGRCQLRSFVESMGFARSGGLWDQCFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJK5</accession>
    <name>E3QJK5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CVNH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_06187</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ31043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095063.1">
        <property type="nucleotide sequence ID" value="XM_008096872.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJK5"/>
    <dbReference type="GeneID" id="24411552"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06187"/>
    <dbReference type="eggNOG" id="ENOG502T4FK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_123980_0_0_1"/>
    <dbReference type="OrthoDB" id="2947935at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.60.10">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011058">
        <property type="entry name" value="Cyanovirin-N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036673">
        <property type="entry name" value="Cyanovirin-N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08881">
        <property type="entry name" value="CVNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51322">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180515" evidence="1">
        <location>
            <begin position="20"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Cyanovirin-N" evidence="2">
        <location>
            <begin position="31"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ31043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="167" mass="18191" checksum="4551DCCEF65756DC" modified="2011-01-11" version="1">MRFLSITAVLSAVAVAVSARDCPLESDCVQKSCKNFQLHFLDPDALRSIREWKLTADCKDNAGNKMVTQLYLEECLANTDGNLIWSPGGGFRCFGCKLTNTNPLTMECGCMNKKDKIQTRVVNLSEGIWVYDGAIGCYQTGTGTALKGIVGYNYNAGLLKSPGIGKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJM7</accession>
    <name>E3QJM7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_06209</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ31065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095085.1">
        <property type="nucleotide sequence ID" value="XM_008096894.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJM7"/>
    <dbReference type="GeneID" id="24411574"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06209"/>
    <dbReference type="eggNOG" id="ENOG502R163">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1402318_0_0_1"/>
    <dbReference type="OrthoDB" id="10339252at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ31065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="194" mass="22323" checksum="34F2AD22161B32D1" modified="2011-01-11" version="1">MDQDNMASQEEELSDCEHCRRIFVEQPVEEAFFISSALRRKAKAEKLLDDFDQCQLTRGQLQRYLALADKLEDSVMRRAARFGHVVQATTACWLVHKPNLSDEDRDVLMQDERVAGMVAIVAGFEKALSGFVLASRDPKLREAHEALGVGRPDWEKNYDLSVEEWRENGIDAIEEDVDDAKQRRRRCQLLGKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJR8</accession>
    <name>E3QJR8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">pectin lyase</fullName>
            <ecNumber evidence="10">4.2.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_06250</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>Eliminative cleavage of (1-&gt;4)-alpha-D-galacturonan methyl ester to give oligosaccharides with 4-deoxy-6-O-methyl-alpha-D-galact-4-enuronosyl groups at their non-reducing ends.</text>
            <dbReference type="EC" id="4.2.2.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the polysaccharide lyase 1 family.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.10" evidence="10"/>
    <dbReference type="EMBL" id="GG697353">
        <property type="protein sequence ID" value="EFQ31106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095126.1">
        <property type="nucleotide sequence ID" value="XM_008096935.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJR8"/>
    <dbReference type="STRING" id="645133.E3QJR8"/>
    <dbReference type="GeneID" id="24411615"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06250"/>
    <dbReference type="eggNOG" id="ENOG502RZWS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021980_0_1_1"/>
    <dbReference type="OrthoDB" id="1637350at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030570">
        <property type="term" value="F:pectate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047490">
        <property type="term" value="F:pectin lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.20.10:FF:000003">
        <property type="entry name" value="Pectin lyase F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002022">
        <property type="entry name" value="Pec_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045032">
        <property type="entry name" value="PEL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31683">
        <property type="entry name" value="PECTATE LYASE 18-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31683:SF67">
        <property type="entry name" value="PECTIN LYASE F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00544">
        <property type="entry name" value="Pectate_lyase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00656">
        <property type="entry name" value="Amb_all"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 11 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178542" description="pectin lyase" evidence="12">
        <location>
            <begin position="19"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="Pectate lyase" evidence="13">
        <location>
            <begin position="96"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00036818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00039082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ31106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="396" mass="41955" checksum="09BA4E5DE8A8BFC5" modified="2011-01-11" version="1">MKNLLLFVVAALASTATAQVQGKAFGFAAGTTGGGSAAPQYPSSIAQLKEWLTDSTPRTIMIDRTWDFRNTEGTTHGRCCSDNRTTKCPGGTSKGQAWIQDTCDAASGTWIDCTYDNAAKSPIDINSNKSIVGVGSKGVIVGKGLRVRGGTSNVIIQNIHITNLNPQYVWGGDAITLDGSDKVWIDHCKISLIGRQFVVSGWGAAGKVTISNTEFDGKSEWSAGCNGKHYWAALLIGAKDYYTFSGNWLHDVSGRSPHMGTKKTADSEIIFHGVNNYFQNVGGHAFDIDGNTWVLLEGNYFDSVTTPVTPATLTNGGNIYIVNTVDEASRCTSSLGYICEWNRARDSGVVSSLTSTDALSKLGGFKSSLIGHIGVADVPAKVKANAGVGKTTSTNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>E3QL14</accession>
    <name>E3QL14_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">SH3 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_06841</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DOCK family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697356">
        <property type="protein sequence ID" value="EFQ31552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095572.1">
        <property type="nucleotide sequence ID" value="XM_008097381.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QL14"/>
    <dbReference type="GeneID" id="24412206"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06841"/>
    <dbReference type="eggNOG" id="KOG1998">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000595_0_1_1"/>
    <dbReference type="OrthoDB" id="18896at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08679">
        <property type="entry name" value="C2_DOCK180_related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11684">
        <property type="entry name" value="DHR2_DOCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.350">
        <property type="entry name" value="Dedicator of cytokinesis N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027007">
        <property type="entry name" value="C2_DOCK-type_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026791">
        <property type="entry name" value="DOCK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043161">
        <property type="entry name" value="DOCK_C_lobe_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032376">
        <property type="entry name" value="DOCK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042455">
        <property type="entry name" value="DOCK_N_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027357">
        <property type="entry name" value="DOCKER_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056372">
        <property type="entry name" value="TPR_DOCK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45653">
        <property type="entry name" value="DEDICATOR OF CYTOKINESIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45653:SF10">
        <property type="entry name" value="MYOBLAST CITY, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14429">
        <property type="entry name" value="DOCK-C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16172">
        <property type="entry name" value="DOCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23554">
        <property type="entry name" value="TPR_DOCK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51650">
        <property type="entry name" value="C2_DOCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51651">
        <property type="entry name" value="DOCKER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="8">
        <location>
            <begin position="7"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="C2 DOCK-type" evidence="9">
        <location>
            <begin position="629"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="domain" description="DOCKER" evidence="10">
        <location>
            <begin position="1461"/>
            <end position="1871"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="90"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="131"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="416"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1792"/>
            <end position="1816"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1866"/>
            <end position="1904"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1930"/>
            <end position="2016"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="90"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="460"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1795"/>
            <end position="1807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1869"/>
            <end position="1902"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="2002"/>
            <end position="2012"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ31552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="2063" mass="228820" checksum="D15E85C0DFD97D38" modified="2011-01-11" version="1">MPWQPLPRIAFAVATYPFAASGPADLPLELGDELYIIEETPDGNWLRGYLVAPPSLLAGLTSVKGQTLEARVFSGIFPRSCVEVREVLGEADDTDDADDAASDDATADTHFGSDSAKSGLTRTAIDIPKAIQRHKSFGNAKGPRGNRTGTKGRTPLQELPNGTHGRLSIPVKRDPDAPRPAAPVPMLKIGDETPTSAAEPLIDEIASCLREWHSTNLHGLLLSRQYSRLEKLSQLIHTLNLSRQQFLHNVLTRHEYQRLREKTVWDLVRVNKLCGGEVVVRDPADRGRVLTGDDSVVDITKLQSVMSVLDEPPQPTVEPTALHHLLFDVKGFAGASAEETSLAAYLVAKPVGGKVTTLTECFIIEIPPGGTIGSLAKSGQTRTVFADLSSQDIGDGASADTELYLVVKVRSSEQIIASRKPDSRSGAKSQGTGYSKDPTKPTSAGNGKPSRRSLMWGSKSGRSAFSRGNATPKLDSLTEYPEARPSTQDDGQGSAPPPSTDGSRPRGSFDAGAGFLMAERTVGVGVLKLNSIMKQDDDVEQVVSIWSASLTPPAEKQSLNDEWDGLIRDLMDSKSGHYEKSRRTERVQVHLRSFNHPDVDELVKTTPTLLAGIRKTNKLGFSGAPTKARSDIYVTLDSAALSKHNLLSRYAGSPTTLASSVQGNHLQVMLEVRRSDGEKIPNCIFSSSNTEGITTWKSVAVERGDHWSQTVRLAISPEDVFTSHLVMFLSDMPNPPFAVAHMPLWNQEAFVRDGTHALLLYKADEFTSTAQAGPSGRGGYLSLQWSARGNEEHSADVTGPQAILRVDTYLCSTRFSQDRVVLGLLKWKEAAKDDIPTLLKHLIFVPEIEVVKLLSDVLDALFGVLVEYSGNDELEDLVFTALVRVLGIVHDRRFNLGPLVDHYAENRFNYPFATACLVRSFTRLLEKPAEPTTSRKLRSTFKVVRHILKFITHARGQQQAKEAGIGITHSHSAPGFTRELRNIFKALDAMMRSHAPVLVGSQTLAVQHFHTWLPELTGLLSTEEILHIAIDFLDSCADVKGKLVLYKLVLIINYSKLDIFSHPDQKSALTANTVRWIAPHWGHTEAVTDSWKEQVRLCCSVLAGQIDNLGPEIPDYLPKIIDSYMSIVAVPTKPRNRLSLLFPTSYPFPCKPVTEKCTFDEALVELSAILSAVSNSPSGMQLELIEGDLTLLLENTLRVHMSILMGEAFPPDWLSVHIYHHKSTMKTLQYLSSILLESYLPHPDDAENFNTELWKMFFTTMLKLVGSPSLALETFPEQKRRAVWKIAGDVREHGAELLRRTWEAIGWETSADERDRYKLSKMGGYQVQYVPTLVGPIVELCLSVHQGLRRMAVEVLQTMIVSEWTLSEDLSVIQTEIIDSLDQYFKSKPLTESILQKLFIGEVLERFAPLATGPDEALHAAICELMGTVNEFLDLLVAVHSSDNTSEASHLINRLRLMEFLRDMQKEEIFIRYVHQLAALQAEARNHCEAGLALRLHADLYDWDPTKQVPALSEPEFPVQTSFERKERIYFDMIKHFEDGEAWSSALAAYRELRTQYESNVFDFAKLARTERAIATVYETISRSDRLIPKYFKVVYKGLGFPSSLRDKEFVYEGSPTERASAFTDRMQELYPSAQIVTGGDVDDVEGQFLVVSAITPHRDLTHQVFQRARVPQVIRDYLLSANPQSFSVSSKRDTSGPVKEHHAEKIVFTTADPFPTILRRSEIVYTEDIKLGARETGLERIVRKTQEMTVIEKRVAEGDEENAQLLVDAVSVSVNPGSDNSVACYRQLLPAASSDDDNGDDDDEEQETRLDPQDNAIKMALVDHAIMIKRCLATFAKSSNEVLNRRHEELRQYFESTFAPEIALFAPQQPTRDFTNIQPWRRSSPSTEQGSPQPQSTTGATDNVVVAEEVSTVQPIAIRQGRGTRLSFLGGRKRQSPVQQQTNSNSSASGDADDTLSQHSRSRSRAQDTSSRLSFFRAPSTDGGRMNGSNDAASEWVTDSGGRQSSDTGFNLTEKEREYRDESLADDPIVIKRSSVRKRLSMLKLGKKSHKHGGVMGSVHEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLD3</accession>
    <name>E3QLD3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_06960</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697356">
        <property type="protein sequence ID" value="EFQ31671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095691.1">
        <property type="nucleotide sequence ID" value="XM_008097500.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLD3"/>
    <dbReference type="STRING" id="645133.E3QLD3"/>
    <dbReference type="GeneID" id="24412325"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06960"/>
    <dbReference type="eggNOG" id="ENOG502T4DW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_528927_0_0_1"/>
    <dbReference type="OrthoDB" id="4851404at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="304"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="20"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="214"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="26"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="101"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="127"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="233"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="280"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ31671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="515" mass="55984" checksum="E5731C5A7CE949A6" modified="2011-01-11" version="1">MDAAGEYTFGDFQSLSNNIWAEQPSQQQQQQQQQQQQQVSDDMMKQLLLAAIAEPQQQPQQQQEQQPLPDNLFEGLNWEDLAQQPLSQELLQQHDPMLFLSGEEQPQQPELPEQPGSQLEGQSEGLFGDDDLFGDEESSSPEVGNEKSLPSPPLPTPSCFSITLPTFDNIPPTPTLPSFPCSLPAPPPLNAGDNEVQCIDPRLLGMPASVAAPVADHPPHGVGEYTQGAQGTEDAKDAKDDDVNMADIPLPSTETPSPRRASVEGTVERALAPNTEGNRVAKKAGKKAGKKATGGPVRAVKANSCDACRRSKTKCVTAEGATDCNACLKKHRTCNVSGVDGRTNKTNRDLLDTTSAAVNNYLRHATLLCTDLAEHPDQKLMVQALLQTMGDFQQVRSIISKVTGSPMKAWPFASGPFRPPTLDGPTKLTYVRNCRDTQLRLMAQNDGKILASLLIMIAFGEAPQITAASGLVDRVMGHNTALVALERSIQENCSFYAEHPIYEHMRKGIEKCFEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLH9</accession>
    <name>E3QLH9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_06692</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697357">
        <property type="protein sequence ID" value="EFQ31717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095737.1">
        <property type="nucleotide sequence ID" value="XM_008097546.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLH9"/>
    <dbReference type="GeneID" id="24412057"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06692"/>
    <dbReference type="eggNOG" id="ENOG502RGZQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2589606_0_0_1"/>
    <dbReference type="OrthoDB" id="10451120at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ31717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="80" mass="9455" checksum="ECAD54376B89C5E6" modified="2011-01-11" version="1">MSCVANYLAEHRDLYERLHTDKEEHDRVKAHQARASLDGRQGFKSWWTGLQAVSFTEKARYHKQALPASKRTYFVSMRQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLP9</accession>
    <name>E3QLP9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cbs domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_06762</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697357">
        <property type="protein sequence ID" value="EFQ31787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095807.1">
        <property type="nucleotide sequence ID" value="XM_008097616.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLP9"/>
    <dbReference type="GeneID" id="24412127"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06762"/>
    <dbReference type="eggNOG" id="ENOG502SDT6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037053_0_0_1"/>
    <dbReference type="OrthoDB" id="5273928at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ31787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="428" mass="49307" checksum="66791A7471B356DA" modified="2011-01-11" version="1">MAMHTVAENIGDVTEQHLAREDLPKRYLWRIWRLLENRGVCFQAWKVFSKLLLAEDDEKTLGLYRYRQHICQPSENLRHYLRPLESVAVDFVTHLSITGFCSFAENELLALGRLKNLAILEIIQPADELRTIFPKVDDRLVRGWLEMENPFPLLRILRLWGDESVTKKSLQYVSRFPSLALYDVNASRSDWRGAADMALREGWEMEEPLHGPHDTLLWYLMLFDFVEESKPRQVQGLARNIDDGLMNFCQSSNQPIKFIPNRDAPSFLDHLGDAAKRNLSMYVDVPGYEAQTCKGFPFETWAFWLYSFIGQFTNDEDLTRVGFETVRKTVSEQLVLPSKPLACLQLGHCGSSRPGITPAVSYVRRGLFATSRYTFFRTSSPSNKQMSARKTAELMKPTVQLGNVETGLNPNRKKRRRLDDILQSFMGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLU6</accession>
    <name>E3QLU6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_06978</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095854.1">
        <property type="nucleotide sequence ID" value="XM_008097663.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLU6"/>
    <dbReference type="GeneID" id="24412343"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06978"/>
    <dbReference type="eggNOG" id="ENOG502T6Y7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_752296_0_0_1"/>
    <dbReference type="OrthoDB" id="4850914at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180590" evidence="2">
        <location>
            <begin position="19"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="281"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ31834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="396" mass="44349" checksum="9C65F2CE0D5D4DE2" modified="2011-01-11" version="1">MRSLTLMPALLALSRAAAIPNPTQPAHLAVSDEDLDAAIKEPLVNFVNGPVYGLPWYPDDPSPPSANPFKPYREDARVDDGVKGTSALSNGAMVWASLELQALAAAAAAARGPNDIDDDAVIPSEEDVRLITDMVLDDGYAFPDDEVLGRRSVETRSRDLEEIAKGPAGAAANATLPADYHRGLTKDQLCSAFGGLTWKASELMTPVYQWQPEYVPWLVDNKGPYVYVLDGLRHMEWILWKINRGLQYTTLFTPEEEQAIVRCWYQFSGIEWQRIRPVNYTNEPSPSRKPVQLSQPSVNKEPLPGPFHPKPWSTPRPSLKKLLRVITVKAPVSRYQSYATRRIHKVLVSLEISLMETMQDPRMRDYIVYDTQKGQGIEQALRLAKEAYDWKLVAPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLZ6</accession>
    <name>E3QLZ6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein rds1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07028</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095904.1">
        <property type="nucleotide sequence ID" value="XM_008097713.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLZ6"/>
    <dbReference type="STRING" id="645133.E3QLZ6"/>
    <dbReference type="GeneID" id="24412393"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07028"/>
    <dbReference type="eggNOG" id="ENOG502QSE0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028606_2_0_1"/>
    <dbReference type="OrthoDB" id="2098436at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039254">
        <property type="entry name" value="Rds1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38705">
        <property type="entry name" value="PROTEIN RDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38705:SF1">
        <property type="entry name" value="PROTEIN RDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13668">
        <property type="entry name" value="Ferritin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180694" description="Protein rds1" evidence="1">
        <location>
            <begin position="22"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="468" mass="51241" checksum="ABFE1B966FC38589" modified="2011-01-11" version="1">MAPRSILQSAGLLALASGAFAVPFVSKAQTTVYSEPTVTASQVPHTNVTSHGPYTGPPPSTTGAISTKILASEVPILPPPDDAYDYPADGKLHGDQPAPYTPSGGIGTNGSAPVYRVQSDFDYQSLALGLYQEYIELDLFHWGLATYSDADFEELGLNAEDRFLLQHMADQEIGHATVITNMLGPQAPQQCTYNYPVSNLREYIDFNQKLTRWGEAGVYGFLPHLNSGPAAQLLLQSITIEARQQMIFRQFEGLFPMPEWHTVGIPQSWAWTLLAPYISSCPWNQTRLIWQNFPALHILNQPNPYRINGADVWNETTGGWANTAATTNISEAESCVNAADSSQDCKAAISHNRTIPLSYPGRQVFFQWDAPGQAVGPNNSYITATNVVEPKFAAWVSQLNVTYSPLMNVSLDSRTAYAIQPNVSTWEHDPAINSTMFVALTDSDLYVTPHNLTMINPHVAALAMYQAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QM16</accession>
    <name>E3QM16_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Quinone oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_07048</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WrbA family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095924.1">
        <property type="nucleotide sequence ID" value="XM_008097733.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QM16"/>
    <dbReference type="STRING" id="645133.E3QM16"/>
    <dbReference type="GeneID" id="24412413"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07048"/>
    <dbReference type="eggNOG" id="KOG3135">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051402_0_1_1"/>
    <dbReference type="OrthoDB" id="504689at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003955">
        <property type="term" value="F:NAD(P)H dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.360:FF:000001">
        <property type="entry name" value="NAD(P)H dehydrogenase (Quinone) FQR1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010089">
        <property type="entry name" value="Flavoprotein_WrbA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01755">
        <property type="entry name" value="flav_wrbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002999">
        <property type="entry name" value="PRK03767.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30546">
        <property type="entry name" value="FLAVODOXIN-RELATED PROTEIN WRBA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30546:SF23">
        <property type="entry name" value="FLAVOPROTEIN-LIKE PROTEIN YCP4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="2">
        <location>
            <begin position="5"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ31904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="204" mass="21852" checksum="900F8E8FF1272867" modified="2011-01-11" version="1">MAPKIAIVYYSMYGHIRQLAEAEKKGIEKAGGSADLFQIAETLPEEVLAKMHAPPKPSDIPVLNDPATLEAYDAFLIGIPTRYGNFPTQWKAFWDMTGKQWSSGGFWGKMAGLFISTASLGGGQESTALAAMSTFAHHGIIYVPFGYAKAFAQLTDLSEVHGGGPWGAGTFAGADGSRQPSAKELEIATIQGETFYQTVAKHFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QML8</accession>
    <name>E3QML8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphatidate cytidylyltransferase, mitochondrial</fullName>
            <ecNumber evidence="6">2.7.7.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">CDP-diacylglycerol synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">GLRG_07250</name>
    </gene>
    <organism evidence="21">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TAM41 family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.41" evidence="6"/>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096126.1">
        <property type="nucleotide sequence ID" value="XM_008097935.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QML8"/>
    <dbReference type="STRING" id="645133.E3QML8"/>
    <dbReference type="GeneID" id="24412615"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07250"/>
    <dbReference type="eggNOG" id="KOG2986">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030279_0_0_1"/>
    <dbReference type="OrthoDB" id="341477at2759"/>
    <dbReference type="UniPathway" id="UPA00557">
        <property type="reaction ID" value="UER00614"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004605">
        <property type="term" value="F:phosphatidate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032049">
        <property type="term" value="P:cardiolipin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016024">
        <property type="term" value="P:CDP-diacylglycerol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015222">
        <property type="entry name" value="Tam41"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13619">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13619:SF0">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09139">
        <property type="entry name" value="Tam41_Mmp37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028840">
        <property type="entry name" value="Mmp37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="16" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="17" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="18"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="480"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="18"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00018337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00029893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EFQ32106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="501" mass="57224" checksum="324DD85E69DAAD35" modified="2011-01-11" version="1">MALSRLLASTLSYMFLDAEKKEEDKTKEDRPPPYTHRGSAINFNWAREAEKKERSGPTLSADNWEEHPDARIEDFEELPYKEFGINQHMEVNAEFRKVLNEVVREFRAPIMYAMAYGSGVFPQSKATRTVTDEEFRAVHPKPSPSLMEVQKGGPKMIDFIFGVTHTQHWHSLNIRQHRDHYSGLASFGSGLVSTFQDRWGAGVYFNPYVTKKGMLIKYGVTSIDNLCTDLSTWNNLYLAGRLHKPVKILRDHPRVRLANQVNLISAVRTALLLLPPKFTEKELFSTIAGISYLGDPRMSLPTENKSKINNIVDNNMISFRKLYGPLLNTMPNVDFADGADQQSKHASDAEYDGAMYQDMDPIKRGNMVRRLPKAFRSRLYFQYQKKSMVPASEFKAMMDASKEEEDVSFKRREGGGFEQRIVQDDPDELRKSIRKVIRQTVNWPATAQSVKGLFTAGVGRSIRYLSEKLTKYNEGKAKAKVKAEELKKQESEAADKAKKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMP8</accession>
    <name>E3QMP8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">LYC1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07280</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096156.1">
        <property type="nucleotide sequence ID" value="XM_008097965.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMP8"/>
    <dbReference type="STRING" id="645133.E3QMP8"/>
    <dbReference type="GeneID" id="24412645"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07280"/>
    <dbReference type="eggNOG" id="ENOG502S41G">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1906330_0_0_1"/>
    <dbReference type="OrthoDB" id="2020070at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055100">
        <property type="entry name" value="GNAT_LYC1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053013">
        <property type="entry name" value="LAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34815">
        <property type="entry name" value="LYSINE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34815:SF4">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22998">
        <property type="entry name" value="GNAT_LYC1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LYC1 C-terminal" evidence="1">
        <location>
            <begin position="9"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="149" mass="16816" checksum="A042174B547FD413" modified="2011-01-11" version="1">MRSKGPSHPNCERLILIASRSVVWAVWTRGYYGGLKRPEKGNTMHILRLAVEEDESEANAGSRAAGAADDDAFVQDAVEALLRLAHAEAAEWRVNNIELWNPDPRVRALIERAGIPHEFVERETESIASLMWYGEGEVEWVLNEKFGWC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMV8</accession>
    <name>E3QMV8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mob1/phocein family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_07340</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697360">
        <property type="protein sequence ID" value="EFQ32196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096216.1">
        <property type="nucleotide sequence ID" value="XM_008098025.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMV8"/>
    <dbReference type="STRING" id="645133.E3QMV8"/>
    <dbReference type="GeneID" id="24412705"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07340"/>
    <dbReference type="eggNOG" id="KOG0440">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038321_4_1_1"/>
    <dbReference type="OrthoDB" id="8170117at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005935">
        <property type="term" value="C:cellular bud neck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031097">
        <property type="term" value="C:medial cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035974">
        <property type="term" value="C:meiotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071958">
        <property type="term" value="C:new mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071957">
        <property type="term" value="C:old mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902554">
        <property type="term" value="C:serine/threonine protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034973">
        <property type="term" value="C:Sid2-Mob1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030295">
        <property type="term" value="F:protein kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000281">
        <property type="term" value="P:mitotic cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903473">
        <property type="term" value="P:positive regulation of mitotic actomyosin contractile ring contraction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031031">
        <property type="term" value="P:positive regulation of septation initiation signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007096">
        <property type="term" value="P:regulation of exit from mitosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.30">
        <property type="entry name" value="MOB kinase activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005301">
        <property type="entry name" value="MOB_kinase_act_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036703">
        <property type="entry name" value="MOB_kinase_act_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22599">
        <property type="entry name" value="MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03637">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01388">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101152">
        <property type="entry name" value="Mob1/phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR605301-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ32196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="283" mass="31960" checksum="1B88A3DD204B4F62" modified="2011-01-11" version="1">MISLLQYLSVRTGLLVGIPPLQPPVAPPAVPDPPRSHGGGSIGRDLTVINRSEPQIPKPVLIAADDDCAEDSNQKAARNQFRARTVKGANNGVALRQYAEATLGGGSLRKVVKLPEGEDENEWMAVNMVDFYNQINLLYGAITEFCSPQSCPEMKATDEFEYLWQDNENYKRPTKMAAPDYIEHLMAWVQRHIDDEQILPSRIGVPFPKSFPSTVRQIFKRMYRVYAHVYCHHYAVIRELGLEPHLNTSFKQYVLFVDEHKLASGKDFYGPLNDLAEKMIESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNB0</accession>
    <name>E3QNB0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">H/ACA ribonucleoprotein complex subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Nucleolar protein family A member 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_07492</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Common component of the spliceosome and rRNA processing machinery.</text>
    </comment>
    <comment type="function">
        <text evidence="3">Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
            <location evidence="3">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the eukaryotic ribosomal protein eL8 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697361">
        <property type="protein sequence ID" value="EFQ32348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096368.1">
        <property type="nucleotide sequence ID" value="XM_008098177.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNB0"/>
    <dbReference type="STRING" id="645133.E3QNB0"/>
    <dbReference type="GeneID" id="24412857"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07492"/>
    <dbReference type="eggNOG" id="KOG3167">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084513_0_0_1"/>
    <dbReference type="OrthoDB" id="5364946at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031429">
        <property type="term" value="C:box H/ACA snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031120">
        <property type="term" value="P:snRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050257">
        <property type="entry name" value="eL8/uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002415">
        <property type="entry name" value="H/ACA_rnp_Nhp2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004037">
        <property type="entry name" value="Ribosomal_eL8-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23105">
        <property type="entry name" value="RIBOSOMAL PROTEIN L7AE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00883">
        <property type="entry name" value="NUCLEARHMG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01082">
        <property type="entry name" value="RIBOSOMAL_L7AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="5">
        <location>
            <begin position="98"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="190"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="27"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="191"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="209"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ32348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="241" mass="26139" checksum="07CF1E994F5CC6C5" modified="2011-01-11" version="1">MAAEKPDRKEKKDKKRSVSDGAIKKDKKDKKDKKDKKDKKDKKDKLERVLDEHLQADVAATAVASGEIASKATADGLPVAGALVPFAVPLADEKAMKKVMKSIRKAAKNNTLKRGVKEVVKTLRKSPAAGPGNTAFPGVVIIAGDISPMDVISHLPVLCEDHNVPYIFVTSRAELGAAAKTKRPTSVVMVSEKRSAADAKKAEKKSDVKDDEEDDGEDYSEVYSALVKLVQKETAKQSFWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNH9</accession>
    <name>E3QNH9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07736</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697362">
        <property type="protein sequence ID" value="EFQ32466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096486.1">
        <property type="nucleotide sequence ID" value="XM_008098295.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNH9"/>
    <dbReference type="GeneID" id="24413101"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07736"/>
    <dbReference type="HOGENOM" id="CLU_2277295_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180754" evidence="1">
        <location>
            <begin position="21"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="102" mass="11269" checksum="75D121686C02737C" modified="2011-01-11" version="1">MKFIQLLLQAACLTPALVVALPLKPAGGEDFQTYGNLIPNERREALPLEPAGGEDFQTYGNLIPKERREALPLEPAGGEDFQTYGNLIPREAKHARPNEHSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNJ4</accession>
    <name>E3QNJ4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Sugar porter family MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_07751</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697362">
        <property type="protein sequence ID" value="EFQ32481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096501.1">
        <property type="nucleotide sequence ID" value="XM_008098310.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNJ4"/>
    <dbReference type="GeneID" id="24413116"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07751"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_11_5_1"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000078">
        <property type="entry name" value="MFS maltose transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF83">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="141"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="195"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="285"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="407"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="443"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="471"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="504"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="550"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="579"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="141"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ32481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="641" mass="70873" checksum="42786CEEFD4B1060" modified="2011-01-11" version="1">MASSHDGVRFEKLASRRSSPKPPLDSHRASAPHDADDDDDEAFALLSGNDSLLSDTDDIELDDLESVDGHHASSSLGHDRPGHTRGLHEAEGWIQDAINAERSLTRREAIRAYPMAIFWSLVVSLCVIMEGMSIAPISISLLIFLPLAFFTTSIGLAYWSCYDTILISSFFAHPEFSKKYGDKKDSLGRDQLSPMWQAILGNSSTFGCIVGVLANGFIVERHGQKAALVGSLCVLSGCIFITFFAVDKVMLMLGQIACGLPWGVFASSAPAYASEVLPLALRVYLTTWTNMCFIIGQLISAAVLAGLLPRRDEWSFRIPFALQWSWPVLLVPALLFAPESPWHLVRAGRLDEAEQALARLQRRKASSLDAKARLREIIETDRLEQAHQTGTSYWDCFRGVERRRTEIACVAFAGQVLSGSTFAYNSVYFFQQAGLKPQDNYDLNVGGTALALVGTVVNWLALMPYFGWRRIYLWGMASMAAILFFIGVLDQIARAPGAEAAAELIGWVQACLTLVWTFTFQLSVGQLGWAIPAEVGSTRLRQKTICVARFTYYIFGLLASTVQPYLMNPTALNLKGTTGFVWGGSAFATFVWAYFRLPETKGRTYEELDFLFHNNVPTRDFESTEVEIFDGGEKILSPPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPA3</accession>
    <name>E3QPA3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_07835</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697364">
        <property type="protein sequence ID" value="EFQ32691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096711.1">
        <property type="nucleotide sequence ID" value="XM_008098520.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPA3"/>
    <dbReference type="STRING" id="645133.E3QPA3"/>
    <dbReference type="GeneID" id="24413200"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07835"/>
    <dbReference type="eggNOG" id="ENOG502RX4Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1269538_0_0_1"/>
    <dbReference type="OrthoDB" id="443402at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF5">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="27"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ32691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="218" mass="25172" checksum="CF565F71F4744185" modified="2011-01-11" version="1" fragment="single">MKQMCSHEHVQSLLEAWARTCNRQLVFAKHFFFNIGTGHQKSLPGMYRTLLHGILESCPDLTRSALPNLWTKARGTPWQVGKEVHVSDRDVRKAFDYIVESSKTDDKLGFCFFIDGLDELENTSEFSHGDLVSLLNDWHRRSSGHVKLVVSSREHNVFVDGFSTSQRICLHEITRWDLERFSKDKLNGIQSSQVRDEIVYKIVEKAQGIFFWVTLVVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPE7</accession>
    <name>E3QPE7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MGT family Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_07879</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697364">
        <property type="protein sequence ID" value="EFQ32735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096755.1">
        <property type="nucleotide sequence ID" value="XM_008098564.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPE7"/>
    <dbReference type="STRING" id="645133.E3QPE7"/>
    <dbReference type="GeneID" id="24413244"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07879"/>
    <dbReference type="eggNOG" id="KOG1192">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000537_4_0_1"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010610">
        <property type="entry name" value="EryCIII-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050426">
        <property type="entry name" value="Glycosyltransferase_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050:SF13">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE UGT80A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06722">
        <property type="entry name" value="EryCIII-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Erythromycin biosynthesis protein CIII-like C-terminal" evidence="2">
        <location>
            <begin position="302"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ32735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="431" mass="46298" checksum="A18C1B0B3E5E0F5E" modified="2011-01-11" version="1">MHLSTWDGSAAITADRKHLKFLLHCFSATGHVLPMQAVARELVERGHEVVWTTIAPQEARVVASGAKFFPAEEVIKVDANMDGADPKDMAETAEIMFGGRVTAQVADIRRVLKVFKPDFVLNDALPQGVAALFELDEIPHYATLGVVPLYLPDIGPEPIEHAAQSPLGLLLSQPQLSLPTINSERQKLGLPALKVTDAFSYSPFLHIQASCPSLEFQEGPEPVLPQAQYVGPLVTRVAGANLGVPTWWDDVVNATSVIGITQGTFAMNPTSLIIPAIQALQGDKRHLLVVPSKLADEIREKISVEDNVRIAEWVPYDMLLPRCRLLVTNGGYGSVTQALSHGVPLVCAGTSEDKKDTAARVTWVGAGIDLKTDTPSVNQVRDAVHRVLEENTFAKNAAKVGKELNSQGGAKKACDLLEKAALELGAATASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPV8</accession>
    <name>E3QPV8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Signal recognition particle receptor subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_08029</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SRP receptor beta subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697365">
        <property type="protein sequence ID" value="EFQ32885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096905.1">
        <property type="nucleotide sequence ID" value="XM_008098714.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPV8"/>
    <dbReference type="STRING" id="645133.E3QPV8"/>
    <dbReference type="GeneID" id="24413394"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08029"/>
    <dbReference type="eggNOG" id="KOG0090">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052538_0_0_1"/>
    <dbReference type="OrthoDB" id="41266at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04105">
        <property type="entry name" value="SR_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019009">
        <property type="entry name" value="SRP_receptor_beta_su"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09439">
        <property type="entry name" value="SRPRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="77"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="79"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="92"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ32885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="297" mass="31708" checksum="E93E838D8E63F899" modified="2011-01-11" version="1">MADKMGSFTDFLELIMTPSMPVLAIGAAIVLLFPILLHYILIKSTPYTTLPSVLLLGPAGAGKTALLTLFERGDAPAATHTSQRPQTVELTASRDSKTAHSFRNHDDTSGTHTKFLLVDTPGHGKLRNHAMDKLSAAAAVTDKSKLRAILFVVDAAAIGENDVLAPTAGYLYDVLLALQKRAASGKSSKPPAPVPVLVAANKTDLFTALPATLVKSSLEAEITRIRSSRSKGLLDSGVGIDDVGSEEHDDWLGAYGTEKFTFDQLREFDIDVDVIGGNITGSGSGPDKWWSWIAQRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQ55</accession>
    <name>E3QQ55_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycosyl hydrolase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_08137</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697366">
        <property type="protein sequence ID" value="EFQ32993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097013.1">
        <property type="nucleotide sequence ID" value="XM_008098822.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQ55"/>
    <dbReference type="STRING" id="645133.E3QQ55"/>
    <dbReference type="GeneID" id="24413502"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08137"/>
    <dbReference type="eggNOG" id="KOG2024">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006501_4_0_1"/>
    <dbReference type="OrthoDB" id="408532at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004566">
        <property type="term" value="F:beta-glucuronidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019391">
        <property type="term" value="P:glucuronoside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000080">
        <property type="entry name" value="Beta-glucuronidase UidA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006103">
        <property type="entry name" value="Glyco_hydro_2_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10066">
        <property type="entry name" value="BETA-GLUCURONIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10066:SF67">
        <property type="entry name" value="BETA-GLUCURONIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02836">
        <property type="entry name" value="Glyco_hydro_2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 2 catalytic" evidence="5">
        <location>
            <begin position="19"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="228"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ32993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="239" mass="27240" checksum="68CC88B7E1D659AB" modified="2011-01-11" version="1">MPFWCAVLVLENLHAGTRRSNSSSSSRHGKATRELVARDKNHSSVVMWAIANEPGASEPGAREYFEPLVALARRLDPTRPLCYANEYQASVDRCLMSDLFDVLCLNRYYGWYLHTGDLEAAEEGLEAELRGWAAKFEKPIIVSEYGADTLAGLHTVGDVPWSEEYQSRVLEISHRVFDRVDSVVGEHVWNFAHFQTPSSFIFRVDGNKKGVFTRDRRPKMAAHTLRKRWTEQKPKDLTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQ58</accession>
    <name>E3QQ58_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA polymerase II holoenzyme cyclin-like subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_08140</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclin family. Cyclin C subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697366">
        <property type="protein sequence ID" value="EFQ32996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097016.1">
        <property type="nucleotide sequence ID" value="XM_008098825.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQ58"/>
    <dbReference type="STRING" id="645133.E3QQ58"/>
    <dbReference type="GeneID" id="24413505"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08140"/>
    <dbReference type="eggNOG" id="KOG0794">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034754_2_0_1"/>
    <dbReference type="OrthoDB" id="10266018at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20513">
        <property type="entry name" value="CYCLIN_CCNC_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20546">
        <property type="entry name" value="CYCLIN_SpCG1C_ScCTK2-like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043198">
        <property type="entry name" value="Cyclin/Ssn8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10026">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028758">
        <property type="entry name" value="Cyclin, C/H/G types"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0195">Cyclin</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="4">
        <location>
            <begin position="53"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ32996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="317" mass="36479" checksum="1717FB96551869C1" modified="2011-01-11" version="1">MAANYWESTQRRFWLFSKDELQDVRQKLEDDNAELVQMFPLPQPRHLAIFFNQQVNRLGKRMVIRQQAMATAQVYIKRFYTKVEIRRTNPYLVVATALYLACKMEECPQHIRLIVSEARSLWPDFLSLDTSKLGECEFFMISEMSSQLIVHAPYRTLNNYQQELHLTQDDVNLGWSIINDHYMTDLPLLYPPHIIALTAILLVLILRPSSNMTGSNQPTAAGIAAASAALAQAQGRMPGLPPTPGTPNLADKEKQPEARFGRVQRYGAWLAECNVEIPPMVDCTQEMISFYECHDQYNDKLTREQINRFVKARVLDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQQ6</accession>
    <name>E3QQQ6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10">Signal recognition particle subunit SRP68</fullName>
            <shortName evidence="10">SRP68</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_08338</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the SRP68 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697368">
        <property type="protein sequence ID" value="EFQ33194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097214.1">
        <property type="nucleotide sequence ID" value="XM_008099023.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQQ6"/>
    <dbReference type="STRING" id="645133.E3QQQ6"/>
    <dbReference type="GeneID" id="24413703"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08338"/>
    <dbReference type="eggNOG" id="KOG2460">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018649_2_0_1"/>
    <dbReference type="OrthoDB" id="10255118at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005786">
        <property type="term" value="C:signal recognition particle, endoplasmic reticulum targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030942">
        <property type="term" value="F:endoplasmic reticulum signal peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005047">
        <property type="term" value="F:signal recognition particle binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15481">
        <property type="entry name" value="SRP68-RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3450.40">
        <property type="entry name" value="Signal recognition particle, SRP68 subunit, RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026258">
        <property type="entry name" value="SRP68"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034652">
        <property type="entry name" value="SRP68-RBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038253">
        <property type="entry name" value="SRP68_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12860">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 68 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12860:SF0">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE SUBUNIT SRP68"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16969">
        <property type="entry name" value="SRP68"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038995">
        <property type="entry name" value="SRP68"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 10" id="KW-0733">Signal recognition particle</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="370"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="581"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="378"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="598"/>
            <end position="607"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR038995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ33194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="615" mass="67588" checksum="041EBE69FBF0B1FC" modified="2011-01-11" version="1">MDITKFVVSGRDAALLYGDYATYQNQLAKKLLNSRKKLGIATRNRGKFSKKGDVTATQIAENHEYIHLLLLMSERAWANAMAIKSSHASDAKGVTGKTRSHIVSRLEKAAKTAEQLVELLSQSDAGATQNDKLESRAYAAQIRGAAQFEKQHWEPSLKSYAVSRIIYNAMATSTKGDIFKDLLSDTIDPSIRYAAYQLKTPRTIPIPAIASRAFPQSDIALVQQINEIDPNLLKQAQTEVAKEGEGAENAPRTLTWRSREVQIEDAAISLAWGRVEEAKAKLSEQWPSLSNAEPRDMAAAYDDILEATQDAADATKEAIDELRGEGVSQGDSRMQSLQITRTAVNYEMISWRIGRNRVLTGRDDGLAENYSSLRKKSKDGTAKKSKEETPGRKAAKLKELVALYEGTLQSLEAARELPGVANDEDLAEQLESTAQYFQALKSLSIARSHAIIGNTVNALALTKHATSEAQEAASTLAGGAQHNINSPRNIDVSSNDAKALTNFLQGELQRYRALVHLSNLLRNAESSEDDTKNVPLIERLREYPSGGTDLANLVNIPPKLSTIPVKPIFLDVAWNYIDYPGKEPQEVAPPNQDEHASESGTKSQSQKRGWFGFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>E3QR78</accession>
    <name>E3QR78_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">DNA-directed RNA polymerase subunit beta</fullName>
            <ecNumber evidence="14">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">GLRG_08645</name>
    </gene>
    <organism evidence="23">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol III is composed of mobile elements and RPC2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 14">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="14"/>
    <dbReference type="EMBL" id="GG697370">
        <property type="protein sequence ID" value="EFQ33366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097386.1">
        <property type="nucleotide sequence ID" value="XM_008099195.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QR78"/>
    <dbReference type="STRING" id="645133.E3QR78"/>
    <dbReference type="GeneID" id="24414010"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08645"/>
    <dbReference type="eggNOG" id="KOG0215">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000524_5_1_1"/>
    <dbReference type="OrthoDB" id="10248617at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006386">
        <property type="term" value="P:termination of RNA polymerase III transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006384">
        <property type="term" value="P:transcription initiation at RNA polymerase III promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
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        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
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    <dbReference type="FunFam" id="2.40.270.10:FF:000011">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1100.10:FF:000019">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1100.10:FF:000020">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1110.10:FF:000006">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1800.10:FF:000002">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1070.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="entry name" value="DNA-directed RNA polymerase, subunit 2, domain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1800.10">
        <property type="entry name" value="RNA polymerase alpha subunit dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1110.10">
        <property type="entry name" value="RNA polymerase Rpb2, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037034">
        <property type="entry name" value="RNA_pol_Rpb2_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007646">
        <property type="entry name" value="RNA_pol_Rpb2_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007647">
        <property type="entry name" value="RNA_pol_Rpb2_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007175">
        <property type="entry name" value="PRK09606.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04566">
        <property type="entry name" value="RNA_pol_Rpb2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04567">
        <property type="entry name" value="RNA_pol_Rpb2_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF04560">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 14" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 14" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 14" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RNA polymerase beta subunit protrusion" evidence="18">
        <location>
            <begin position="41"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="17">
        <location>
            <begin position="191"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="19">
        <location>
            <begin position="453"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="20">
        <location>
            <begin position="555"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="21">
        <location>
            <begin position="637"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase subunit 2 hybrid-binding" evidence="15">
        <location>
            <begin position="684"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="16">
        <location>
            <begin position="1058"/>
            <end position="1143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
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    </evidence>
    <evidence type="ECO:0000256" key="7">
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    </evidence>
    <evidence type="ECO:0000256" key="8">
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            <dbReference type="ARBA" id="ARBA00022833"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00023242"/>
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            <dbReference type="ARBA" id="ARBA00048552"/>
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            <dbReference type="ARBA" id="ARBA00053978"/>
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    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000434"/>
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            <dbReference type="RuleBase" id="RU363031"/>
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            <dbReference type="Pfam" id="PF04560"/>
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        <source>
            <dbReference type="Pfam" id="PF04561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
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            <dbReference type="Pfam" id="PF04563"/>
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    </evidence>
    <evidence type="ECO:0000259" key="19">
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            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF04566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF04567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="EFQ33366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1151" mass="129685" checksum="BA7870513150865E" modified="2011-01-11" version="1">MQDDGFEALLEPFYNGKKLTDPISTKEDKFQLLPAFLKVKGLVKQHIDSYNFFVENEIKEIVRANRIIRSDVNSSFWLEFTDIRVERPSRVDFNDIRAQNEVTPMECRLRDMTYAAPIMVDIAYIRDKSKIVRKNVPLGRLPVMLKSSICRLGGANNAEMSRMNECPLDPGGYFIINGTEKVILIQEQLSKNRVIVEADEKNSVITASVTSSTHERKSKTYVTLKKDRILLTANILVEGIPIVIILKALGGLTDYEIMQLVAGDNGKYQDEFLVQFEEATKAGVYTQQQALEYIGARVKMGKSRVPFAAQVRRNHVEEALDALANLIIAHVPIEGLDFYPKAIYVAFMTRRVLMAQNDPSLVDDRDFVGNKRLELAGQLLSLLFEDLFKQFCGNVKSSIDKVLKKDNRAVPLDAVNMISNHANMIGQGINRAIQTGNWTVKRFNMNRAGVTHVLSRLSYISALGMMTRISSQFEKTRKVSGPRALQPSQWGMLCTSDTPEGEACGLVKNLALMTHITTNVEEAPVKRWVFTLDAGVEPIRNFSGGEMHRETSYVIHINGTPFALTRYPKRFAGKFRTMRRRGWISPFVSIHINNHFNAVHIATDEGRICRPYIIVRNGKPKLKEEHLRLLQLGRATFDDFLTHGIVEYLDVNEENDTLVALYEKDVTPLTTHMEIEPFTVLGAVAGLIPFPHHNQSPRNTYQCAMGKQAIGAIAYNQFNRIDTLLYTLVYPQRPMVISKTIQLVNYDKLPAGQNATVIVMSYSGYDIEDALVLNKASCDRGFGRCQVFRKYTAELQKYPNGRRERIGDPVNDENGRTTKHEALDDDGLAIVGYKVNSGEVMIKKETPLDTGSTGIGMDRGPSEFRDSSISYRIADPAYIDKVMVSHTERETMVVKVQTRQTRRPELGDKFSSRHGQKGVVGIIVDQEDLPFSDTGLVPDIIMNPHGFPSRMTVGKLLECLTGKASVLDGRKDYGFGDAFRSHPLEQMSAALVDHGFSWEGKDYFTSGITGEPLEAYIFNGPIYYQRLKHMVQDKMHSRSRGPRAILTRQPTEGRSRDGGLRLGEMERDCLIAYGASQLLLERLMISSDGTQIDICQQCGLFGYKGYCHTCKSTREVTQMTMPYAAKLLVQELISMNVGVRLQLEDEFPHPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QR83</accession>
    <name>E3QR83_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA recognition domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_08650</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
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                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
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                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
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            <dbReference type="DOI" id="10.1038/ng.2372"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
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            <location evidence="1">Nucleolus</location>
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    </dbReference>
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    </dbReference>
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            <end position="350"/>
        </location>
    </feature>
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        </location>
    </feature>
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        <location>
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        </location>
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        </location>
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</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
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            <authorList>
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                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
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                <person name="Place M."/>
                <person name="Proctor R.H."/>
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                <person name="Rounsley S."/>
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                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
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                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EFQ33556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSM6</accession>
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        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
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                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
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                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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    <dbReference type="HOGENOM" id="CLU_2996416_0_0_1"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ33864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="57" mass="6901" checksum="311C5C4D591F5CB2" modified="2011-01-11" version="1">MSNYDRFLLLNSFSRLRDQTQMGAYVYQSTMKHCKMPKSAFYQQWKTSLMSLPLNWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSR0</accession>
    <name>E3QSR0_COLGM</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_09042</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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    </dbReference>
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    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09042"/>
    <dbReference type="HOGENOM" id="CLU_3124937_0_0_1"/>
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        <source>
            <dbReference type="EMBL" id="EFQ33898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="50" mass="5567" checksum="6D070CEC3A39D422" modified="2011-01-11" version="1">MPSMTNQEPIEHRLLLSITGGNTGETKDVNRCTKIFAQAGADSQQFRNLF</sequence>
</entry>
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        <name evidence="5" type="ORF">GLRG_09114</name>
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    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
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                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EFQ33970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    <dbReference type="STRING" id="645133.E3QSY2"/>
    <dbReference type="GeneID" id="24414479"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09114"/>
    <dbReference type="eggNOG" id="ENOG502QTER">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014123_0_0_1"/>
    <dbReference type="OrthoDB" id="301415at2759"/>
    <dbReference type="PHI-base" id="PHI:9109"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056337">
        <property type="entry name" value="LHD_YVC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052971">
        <property type="entry name" value="TRP_calcium_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056336">
        <property type="entry name" value="YVC1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35859:SF5">
        <property type="entry name" value="ION TRANSPORT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35859">
        <property type="entry name" value="NONSELECTIVE CATION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23190">
        <property type="entry name" value="LHD_TRPY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23317">
        <property type="entry name" value="YVC1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="286"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="367"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
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            <end position="449"/>
        </location>
    </feature>
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            <begin position="483"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="513"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="domain" description="YVC1 N-terminal linker helical" evidence="3">
        <location>
            <begin position="38"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="Calcium channel YVC1-like C-terminal transmembrane" evidence="4">
        <location>
            <begin position="239"/>
            <end position="530"/>
        </location>
    </feature>
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            <end position="674"/>
        </location>
    </feature>
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            <begin position="641"/>
            <end position="650"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23190"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF23317"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EFQ33970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTT6</accession>
    <name>E3QTT6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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            <taxon>Colletotrichum graminicola species complex</taxon>
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    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09392"/>
    <dbReference type="eggNOG" id="ENOG502RSG9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1081869_0_0_1"/>
    <dbReference type="OrthoDB" id="4814856at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
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            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="256" mass="28941" checksum="22B3364927BB8331" modified="2011-01-11" version="1">MAQPLKRPLTEAELRRAEDCADENAKLAECWESHQVAIVTCEPADELSFPSYLSTSVLTIETLLPLEQPTPGSPDRKKKQQQQKMREPKRDKRSESSEPRPCYFEHRSYERLDVCTQVARLKASMTFDTLAKEYGTVCIAGYDLRETRRAMESLSIETPARVVWVDLMKVLEHQARGDAGGIPAELHRYTDDNVTVRNGRYDRVPGRPQGYYGMPSVRLLEVLGPAAAAHRADFKKMEKESAALKRMANKARNGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUK1</accession>
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        <submittedName>
            <fullName evidence="6">Dimethylaniline monooxygenase 2</fullName>
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    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_09683</name>
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    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
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        <lineage>
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    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FMO family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697381">
        <property type="protein sequence ID" value="EFQ34539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098559.1">
        <property type="nucleotide sequence ID" value="XM_008100368.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUK1"/>
    <dbReference type="GeneID" id="24415048"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09683"/>
    <dbReference type="eggNOG" id="KOG1399">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006909_8_1_1"/>
    <dbReference type="OrthoDB" id="66881at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000960">
        <property type="entry name" value="Flavin_mOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000332">
        <property type="entry name" value="FMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00370">
        <property type="entry name" value="FMOXYGENASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ34539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="456" mass="52059" checksum="F79E6AE6FC0D4B72" modified="2011-01-11" version="1">MLDKYGPFLSQRDFEEYMESYAVNFDLYKHMTFNTNVKQVVRNADGSKWRVEMIKSGLTEVQEFDKVVFCHGYQTKPKMPVYESQEQYEGLLIHSQQFRKPEDFKGKKVVLVGLGATLSDILSVIVKQTDRAYISHRNGGLIVGRWRNGVPTDLLVTRARRQMSYFLQSHFPKLSNKLVTLASGFLMKQHGKLDPSWRLSENVAPLSVHLAGFVDTTVEILREGKATSLYGIQRFLGGKSIEFTDGTVLDDVDAVICCTGYSADFDLTPFIQMSKPKTDTSGNPYGGRPIARLYKNLFPPAHADSIAILAYSTYGKNNGFSFSDVTSMAISNIWRGISADLIPSRPEMERAIDQHQQWIADRWTLENRSDPGAVKQWEFQGFLHKAAGTGMENLGWGWRGWVTWFKDPYMSYLMNHGVETAHAFRYFETGKRKTWDGAREAIIHTNKLVRRLKQKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUX1</accession>
    <name>E3QUX1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_09803</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697382">
        <property type="protein sequence ID" value="EFQ34659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098679.1">
        <property type="nucleotide sequence ID" value="XM_008100488.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUX1"/>
    <dbReference type="GeneID" id="24415168"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09803"/>
    <dbReference type="eggNOG" id="ENOG502QS40">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029138_0_0_1"/>
    <dbReference type="OrthoDB" id="2548233at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42034">
        <property type="entry name" value="CHROMOSOME 7, WHOLE GENOME SHOTGUN SEQUENCE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42034:SF1">
        <property type="entry name" value="CONDENSATION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ34659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="509" mass="56256" checksum="A16F2C6C8200C727" modified="2011-01-11" version="1">MDQTYPELTWRQTTPGVWQRTADEIEKFYSALATLYEGSSLMFFAITGHISLHIDVRDVGDSTEEAGIIFDKALESAWLAIRCDHPTIASQVTQNLVTGKWTKTYRRCGDLAEQKCWLEETLIHVSGEQTGQQWANNQPPAPKMPTLFVLSPPSHKDGMIRRDLVFRSPHDIIDGVGTLILLSNLVTYASKAFYEGDAYKPPALDGSEAANLSPPYRVAANVPVTLTSDQEKRLADMAAQKAAAMNATDVEVLDVPYRHGASIPGRHQRVARTLTKEQTALLTPACKAANATVTHAFHAAIALVLRDIQKRAPEAKRVRYVNYILRNERASCRAPYNSHRHPAALYHSVPGQSLVVDMDLPAAGDDQVSDGEFLRVVQIMKDFYHGVRNDEEHYALAPTIWAAATPDVPASPRPLPVPPPKTHPSVSISSMGRVDNIIAPKTGAIEVYDPWVTGEELGNGLGLFLGTFRGELYLSAAYNDAWHTAADVLDFLKRCEDVVFKGFDLQFTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVD2</accession>
    <name>E3QVD2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09964</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697384">
        <property type="protein sequence ID" value="EFQ34820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098840.1">
        <property type="nucleotide sequence ID" value="XM_008100649.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVD2"/>
    <dbReference type="GeneID" id="24415329"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09964"/>
    <dbReference type="eggNOG" id="ENOG502T8U2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2072953_0_0_1"/>
    <dbReference type="OrthoDB" id="4186099at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178919" evidence="1">
        <location>
            <begin position="21"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="116" mass="11812" checksum="0D167A427CF63AF9" modified="2011-01-11" version="1">MFHFTAFLIVIAAFAGAASAVSCTPAETYCGSRLIKANKRNRAAVEDALISGRQPIDEAHIKQSVFWCAPAGVPVPAKSGLLFVTYCGPVSTCVEGGALGGVGDACVPSTSGGRGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVI3</accession>
    <name>E3QVI3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cell wall protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10015</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697385">
        <property type="protein sequence ID" value="EFQ34871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098891.1">
        <property type="nucleotide sequence ID" value="XM_008100700.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVI3"/>
    <dbReference type="GeneID" id="24415380"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10015"/>
    <dbReference type="eggNOG" id="ENOG502SR1T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082452_1_0_1"/>
    <dbReference type="OrthoDB" id="2422134at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021054">
        <property type="entry name" value="Cell_wall_mannoprotein_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38123">
        <property type="entry name" value="CELL WALL SERINE-THREONINE-RICH GALACTOMANNOPROTEIN MP1 (AFU_ORTHOLOGUE AFUA_4G03240)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38123:SF6">
        <property type="entry name" value="CELL WALL SERINE-THREONINE-RICH GALACTOMANNOPROTEIN MP1 (AFU_ORTHOLOGUE AFUA_4G03240)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12296">
        <property type="entry name" value="HsbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178925" evidence="1">
        <location>
            <begin position="19"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="222" mass="22702" checksum="53EC429C7C447556" modified="2011-01-11" version="1">MKFTTELTVLTLAMGVFAEPPTKVVAERDLATIQNVITQVGNSLKELNTAVEAFNGDLTGLATAAGGFSNVLSQGTKQVQDTSEITLNEALQLQQFVSGLQSDGNALTKNLDKKKPEFEKANLCGVISSQVGTVGDNAKKLIDAVVSKVPQSVQSVASQLAGGFATTLSSTQQSFGEGNCTNANMAGNSTAPKPSKPATAGSGAVYASLGSIAAAAFAVMLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVU3</accession>
    <name>E3QVU3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphotransferase enzyme family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_10125</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697386">
        <property type="protein sequence ID" value="EFQ34981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099001.1">
        <property type="nucleotide sequence ID" value="XM_008100810.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVU3"/>
    <dbReference type="STRING" id="645133.E3QVU3"/>
    <dbReference type="GeneID" id="24415490"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10125"/>
    <dbReference type="eggNOG" id="ENOG502S072">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049945_0_0_1"/>
    <dbReference type="OrthoDB" id="411145at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004119">
        <property type="entry name" value="EcKL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052961">
        <property type="entry name" value="Oxido-Kinase-like_Enzymes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23020:SF41">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23020">
        <property type="entry name" value="UNCHARACTERIZED NUCLEAR HORMONE RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02958">
        <property type="entry name" value="EcKL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ34981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="459" mass="51692" checksum="82CE41BA16E8F3B2" modified="2011-01-11" version="1">MAAALIQSQQLPSNFTQLVAHTSSPDASFDSTQIFLAAAALSLTMTSLSEPRRVAEIMLSWLGLELVSLTELQTLWAGYGHICAITAKTVNMDRVVGSPKTSPAIRQEADGTYRLIIKLISPPRAKGRDEGHLRKMLSYEVEQYFYQEIAPRLSHDVAVAQCVASTLDMEGKPRAEELQGLTGTIITDLRPQFPVAGEKRLVLNSRQVHASLDWLAKYHSSSWASLPDNLDRFVLPPLEELRRREAGNGPSESKLWLNGGYTYLATRRKEYESLCTDEYSEWSSAFCDPVEGVSSSIAELVAKFLTPSGRPFETYIHGDVKSENLFTTQAGDKVAIFDFQYAGLGVGGCDLAKLFTCSVPVEMLTHHENIPDHLPMDKGEKSLLEQYRETLLSQKPSGKGPADYDWDTFVRHWETALVDWCRFQASWGFWGNTEWLEARVRYILADNEWRKWLKREVQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QW70</accession>
    <name>E3QW70_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Xaa-Pro aminopeptidase family enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10248</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697388">
        <property type="protein sequence ID" value="EFQ35104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099124.1">
        <property type="nucleotide sequence ID" value="XM_008100933.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QW70"/>
    <dbReference type="STRING" id="645133.E3QW70"/>
    <dbReference type="GeneID" id="24415613"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10248"/>
    <dbReference type="eggNOG" id="ENOG502SI2E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017266_9_0_1"/>
    <dbReference type="OrthoDB" id="3632757at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180913" evidence="1">
        <location>
            <begin position="22"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="455" mass="50555" checksum="B7863A98D0018315" modified="2011-01-11" version="1">MHWLTTALIPAAALLWEPVAGDPSPKYNPLPPLREQARIQDAWTAERKAGIPALLKRHGVDAWVVSQREYAEETVFWSLKPASTFSARRRTTCLFLAEPLAANSSEGALPRQPGCIVGWTTDVWETLKAQLEAADPATVAIDAHPEIAFASGLHAGEYQAMANGLGGAWASRMVVKPEIAVEFIATQPRSKLPPYREVMETAWAMIARGFSEAVVVPGKTTTGDLEWWFREEILAHNFTTWFQPSVSVVHQALPWDAETKTEGAAGEDAGGRVIEYGDMLHVDFGLTAMGLNTDTQHLGYVLRPGEEDVPRGLKDGLKKGNKLQDIVRRNIAVGKTGNEMLKASLGEMHTEGIQGRVYTHPIGDWGHSAGPLIGLTNMQDYVPASGELVAVRNMWFSVELLVEHYVPERNQTLWFALEEDVYWAGEEKGWQWVYGRQEEFHLVKAVKEHETMEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWB0</accession>
    <name>E3QWB0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_10288</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697388">
        <property type="protein sequence ID" value="EFQ35144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099164.1">
        <property type="nucleotide sequence ID" value="XM_008100973.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWB0"/>
    <dbReference type="GeneID" id="24415653"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10288"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_2_0_1"/>
    <dbReference type="OrthoDB" id="1935484at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000247">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000106">
        <property type="entry name" value="MFS transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF65">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="192"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="217"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="252"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="285"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="405"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="429"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="525"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="22"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ35144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="584" mass="67409" checksum="5F44699B04D6BF4D" modified="2011-01-11" version="1">MSEKQEVKQPTSLGSESNGKQDASDITKIKPTEEELGKTKNRILQEQAGLRQQDAPIIPILSFFKKKSDYDPNVIATQPSVYDNPSTAKFFQPHPRYENLHRFDPTFRWTWGEELPLISKMDFRITLWACIAFFALDLPRGNLSQANSALFLQSLGMDTNDYNLGNTVFQISFLCAELPSQMISKKLGPDRWIPFIMCSWSIVSGCQFWLSGRTSFLICRALLGILQGGFIPDIVLYLTYFFKSTELPFRLAMFWTVRRITDIVAPLLALGVLRMDGISGYEGWRWLFLVEGIITLSISIWSWFAMAASPTQTKAWWRPQGWFNEQEEKILVNRILRDDPSKSDMHNRQAITPKLLLKSLADYELWPIYIFGLLWEIPAGPPDQYLTLTLRELGFNTNDTNLLSIPPQFLGAIFMLIMTYLSEIWDTRALFGVFTQVWYLPNLVAMAVLPSNSSPWAQYAVVTVLLSYPSPHAMHVSWASRNSHSVRTRAVSAALYNMMVQLARVIYSNIYREDDRPDYRRGNRVLIGICCMNICVYLIAKLFYMRCNKKREKEWNAMTEEARVHYMETTKDEGSNRKDIRFKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QX08</accession>
    <name>E3QX08_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Enoyl-CoA hydratase/isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_10540</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697392">
        <property type="protein sequence ID" value="EFQ35396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099416.1">
        <property type="nucleotide sequence ID" value="XM_008101225.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QX08"/>
    <dbReference type="STRING" id="645133.E3QX08"/>
    <dbReference type="GeneID" id="24415905"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10540"/>
    <dbReference type="eggNOG" id="KOG1679">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_7_6_1"/>
    <dbReference type="OrthoDB" id="410701at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000009">
        <property type="entry name" value="Carnitinyl-CoA dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF171">
        <property type="entry name" value="SD19268P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ35396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="279" mass="29754" checksum="7E351C27FFB2F023" modified="2011-01-11" version="1">MKQVSSRACRAILSSSVDAPHIGKVSIIELNNPKTRNAISWEMLNELDRELDRVYAMASRSEVRAVVIASTHDKVFCAGADLKERQNMTHDEAQQFLTELRRVFSKLEGLPVPSIACVSGLALGGGLELALCCHLRVFSGNAVVGLPETRLAIIPGAGGTYRLPRVVGPSHALDMILTGRRVSAVEAARMGLCNRLVFSGESDCADLDVVRKLTLATALSLARDISAGGPIAIRAALTALAVPHEEAENDAYATVLGTCDRLAALHAFQTKGSPQYLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QX88</accession>
    <name>E3QX88_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Seipin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_10620</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697393">
        <property type="protein sequence ID" value="EFQ35476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099496.1">
        <property type="nucleotide sequence ID" value="XM_008101305.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QX88"/>
    <dbReference type="STRING" id="645133.E3QX88"/>
    <dbReference type="GeneID" id="24415985"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10620"/>
    <dbReference type="eggNOG" id="KOG4200">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043048_1_0_1"/>
    <dbReference type="OrthoDB" id="3990054at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140042">
        <property type="term" value="P:lipid droplet formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd23995">
        <property type="entry name" value="Seipin_BSCL2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009617">
        <property type="entry name" value="Seipin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21212">
        <property type="entry name" value="BERNARDINELLI-SEIP CONGENITAL LIPODYSTROPHY 2 HOMOLOG BSCL2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21212:SF0">
        <property type="entry name" value="SEIPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06775">
        <property type="entry name" value="Seipin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="236"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="266"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="319"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="361"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ35476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="381" mass="41452" checksum="03350B31F125796C" modified="2011-01-11" version="1">MEVLGKASRAATSKTAQRTLVNVSLLVGASLFLLPFAAVASILFFQNYLPDQVVTAPVHLQYGSGVNPFGTAFIPTSALRTQQEYDVSVTLSMPRSPANTHRGNFMIALHLLDAGALSTGYDKLQPQIPPEPYSHFDGKSVLFSSRRPALVPYQDPLISLASRIFFLAYYILFGDSETCVLTVPMAERVELGRGSSLPSSAYLEIQGGQNIETYYASVTLTAQLRGLRWLMYHYRLATLTSAIILFWTSEVLFMVVAWLLWSGLSGSGSSSRTSPGKALEEVSSKAAGRVKREDGSGVDELSDAPRTFPTYGNQAPLRYEPEIKEEAQAGPRMEDLVPLGGEADDEEEDDGRGSYKGDSGIGTSYSEGGSSSVRRRSSHHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXB5</accession>
    <name>E3QXB5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Protein artemis</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">DNA cross-link repair 1C protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">GLRG_10647</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697394">
        <property type="protein sequence ID" value="EFQ35503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099523.1">
        <property type="nucleotide sequence ID" value="XM_008101332.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXB5"/>
    <dbReference type="STRING" id="645133.E3QXB5"/>
    <dbReference type="GeneID" id="24416012"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10647"/>
    <dbReference type="eggNOG" id="KOG1361">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013294_0_1_1"/>
    <dbReference type="OrthoDB" id="5561659at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035312">
        <property type="term" value="F:5'-3' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011084">
        <property type="entry name" value="DRMBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23240">
        <property type="entry name" value="DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23240:SF8">
        <property type="entry name" value="PROTEIN ARTEMIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23023">
        <property type="entry name" value="Anti-Pycsar_Apyc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07522">
        <property type="entry name" value="DRMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA repair metallo-beta-lactamase" evidence="14">
        <location>
            <begin position="415"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="536"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="540"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="569"/>
            <end position="579"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00039759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00042677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF07522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EFQ35503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="629" mass="69685" checksum="F134808269E46227" modified="2011-01-11" version="1">MSTFNGLVAEFPDIRIDFFRSHAGRLPPLACFLSHIHSDHLAGLETLRSPFVYCSAATREMLLRLERYPCRLNYAKGILEARVQTYKHLKNLLKPLPLETTTTLELAPGIHIQVTLFDANHCPGAVMFLIEDSNRAILYTGDIRSEPWFVNSIARNPAVIEYTSGLKTLDKIYLDTSFIRDVPFQTKAEGIAELLRKVASYPTDTIFHIQAWTYGYEQVWIALSKALKSRIHVDDYKMRMFSSLTGKTSNDRFGSSVHLCPEAPALAGYVCGNTPHPGCLTRDEHVRLHSCERGAFCSVVQNARVVSILPVVAHLQNGADVAEAGVGGGGDDLERDAELDPLSAQDIKTMVKLMDETPEIPTDAKMRLLQLMEAGAISGRNMRLDLDMTSFGEKNETAILDAFRTIAQRKQSANEQVVGFSDDSAELPRVITFPYSRHSSYRELCDLVRAFRPKDVWPCTVNIPEWLGGNVTIKSLFGPECSGDIFAHDLEMEKVARERADVLQHQASQDFDANHSSTSQSHQADEASCANAGVGLPTAKLNTAPSAPQQPHWEPQTPNYTGREARETQGPSASGTFTRNAHPLVVTSRIRSDAYLNMVRNVLGGEWTPIGLLSTLDHHTVPDKDLGMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXD1</accession>
    <name>E3QXD1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_10663</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697394">
        <property type="protein sequence ID" value="EFQ35519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099539.1">
        <property type="nucleotide sequence ID" value="XM_008101348.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXD1"/>
    <dbReference type="STRING" id="645133.E3QXD1"/>
    <dbReference type="GeneID" id="24416028"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10663"/>
    <dbReference type="eggNOG" id="ENOG502QVSW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018449_1_1_1"/>
    <dbReference type="OrthoDB" id="4356994at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF49">
        <property type="entry name" value="LYSINE BIOSYNTHESIS REGULATORY PROTEIN LYS14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="56"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ35519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="610" mass="67973" checksum="C3C1AC83AC949ECF" modified="2011-01-11" version="1">MGTSSPEANGDYPGSIGSFLAEAGADGTLGDDERSHIAAVAPRTGEGRSGPRSRNGCWTCRTKKVKCDEQRPNCHRCSRLRLLCDYAPRIKFNKRDKSRKDQLLSSQFAVSSASSAGDGGLPTWAQAVSRLDQSKALSLFSPSAPSVGACSLDLSSADHEAIRYFRTSFAKLNHTKTPDFSLYSIMFDVAQTDSMVMRVVLALGGRELEFRRNKDAEEARGPRTPIQHYSLALRMMADTIGCEDHEQLDLDAVCTALYLMLLYEQKYGDGKCQGLSNHLVGASLILQHRFKNMLLQLPAPSPEVNRKSLALTRKGPDGSGSRLSLYSARILVWISLHDAAAASYGLGGQLNCALHKIMGSLEGPVTAPVFSPFQPMDAFERLHRFSNPLYRSMWADAYPQEELLDDVENRNVYALFGACGQLRFMIAQLANLSCEGNDASQQQRVMAVDMAIQQIGWKFTELLEVAAELSIGTDNSHRLVANIRGIVPHYHAVVLEFMRLTRFNDIPMLSDRQRSALREIMNLAFQAFKHEGDESMARIAWPLFIVALETDDLLHRDWVLSRFQGMSQFSKNLDRAHVFLKQTIEIQNRLGKRVDVRERFQSGEVGLFVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXN6</accession>
    <name>E3QXN6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_10783</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697397">
        <property type="protein sequence ID" value="EFQ35639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099659.1">
        <property type="nucleotide sequence ID" value="XM_008101468.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXN6"/>
    <dbReference type="STRING" id="645133.E3QXN6"/>
    <dbReference type="GeneID" id="24416148"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10783"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_1_3_1"/>
    <dbReference type="OrthoDB" id="6770063at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140115">
        <property type="term" value="P:export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042908">
        <property type="term" value="P:xenobiotic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000011">
        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF60">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="206"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="311"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="350"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="391"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="423"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="456"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="483"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="82"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ35639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="519" mass="56869" checksum="A9CE8FCC685E7C40" modified="2011-01-11" version="1">MSSRDGKGGKDSRPDEMSPQDENGEKDAADALTALPVSDVKQEGSPAVEVEVDAADSLLVKWDGDADPRHPFNWPRSRKWAITILLSNGGLVTLMSGAMLAPSLHAIAQDFGTDEEETQIFLSIFILAFAFGPMVLSPLAEVFGRRPVWILSSCFYILWNTVAGFSRSPGLLIASRVLSGIGASAEFAVTQPVLSDCWVPDERGKSYAIATFIPLLGPAIGPIIGGAVTQSIGWRWTFWILSIYDAVLVIIGVFILSETYEPILLSRQASKLRKGTGKPYFTDAGSESQGLGVKLSRSLMRPLRLLLTQPILQVVAIFLAYNFGILYIVLSTFATLWIRRYGQTESQSGFHYIALVIGYTIAAQVGGKVMDRLWRYLKARSGENTAPEYRVPLMIPGAVLIPLGLLLYGWTAERHTHWIVPDIGIGIFGCGIILNTQAMQAYVIESFRKYVASASAAAQFLRSIAGFAFPIFAPIMYQTLGYGWGNSILALTFVVIGWPAPFLLWRYGAKLRAMGKPQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYH9</accession>
    <name>E3QYH9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Clavaminate synthase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_11025</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697403">
        <property type="protein sequence ID" value="EFQ35917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099937.1">
        <property type="nucleotide sequence ID" value="XM_008101746.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYH9"/>
    <dbReference type="STRING" id="645133.E3QYH9"/>
    <dbReference type="GeneID" id="24416390"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11025"/>
    <dbReference type="eggNOG" id="ENOG502QRGK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045411_1_0_1"/>
    <dbReference type="OrthoDB" id="438224at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.330:FF:000033">
        <property type="entry name" value="Clavaminate synthase-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48420">
        <property type="entry name" value="NON-HAEM DIOXYGENASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48420:SF1">
        <property type="entry name" value="NON-HAEM DIOXYGENASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ35917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="369" mass="40471" checksum="FF106EE96B7D236B" modified="2011-01-11" version="1">MSGPAVNIAQPVVVSLTDLKAGNVPFETLVEAFGPDSLGILVVKDVPPEFPQLRRQALSYASYLGNLSEMQLAKIENPAAKYLTGWSLGKEQLKDGQVDTFKGSFYANCAFYTDPKLDCAKPTAEFSPENFPEYLSPNIWPGEDVLPGFKNSLENLCRLLIDTAVLVARACDQYAEREIDGYTKGYVEHVVSTSNTTKARLLHYYPQSQDNSEVNEDDWCGVHLDHSVLTALTSAMFVDEHTTSTVVSVPETGSTLPPLEEMSGSPDPLAGLYIKSRTGETVQVKIPRDCIAFQTGEALEKITKGKFKAVPHFVRGVRPSMSNGRVARNTLAVFTQPNLGEEVDTDQHITFGEFARGVVRKNTVEAESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYL0</accession>
    <name>E3QYL0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="13">KR domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_10827</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697404">
        <property type="protein sequence ID" value="EFQ35948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099968.1">
        <property type="nucleotide sequence ID" value="XM_008101777.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QYL0"/>
    <dbReference type="GeneID" id="24416192"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10827"/>
    <dbReference type="eggNOG" id="KOG1202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_31_0_1"/>
    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030639">
        <property type="term" value="P:polyketide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05195">
        <property type="entry name" value="enoyl_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056501">
        <property type="entry name" value="NAD-bd_HRPKS_sdrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049552">
        <property type="entry name" value="PKS_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF50">
        <property type="entry name" value="HIGHLY REDUCING POLYKETIDE SYNTHASE SRDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23114">
        <property type="entry name" value="NAD-bd_HRPKS_sdrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21089">
        <property type="entry name" value="PKS_DH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="11">
        <location>
            <begin position="53"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="12">
        <location>
            <begin position="996"/>
            <end position="1296"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="10">
        <location>
            <begin position="2287"/>
            <end position="2366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="8">
        <location>
            <begin position="996"/>
            <end position="1130"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="8">
        <location>
            <begin position="1141"/>
            <end position="1296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="8">
        <location>
            <position position="1028"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="8">
        <location>
            <position position="1206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ35948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="2371" mass="256971" checksum="29EB2FF87ACC9AEB" modified="2011-01-11" version="1">MPGILKSTSSSSRSSEQGDSDGSRAAPERSYLRDDYPAASTPNYSEKPLDEQLEPIAVVGMGCRLPGDVSSASDFWDMLMNKRSGQNPKVPANRFNVEAHYHRNKERPGSLPVMGGYFINEDLENFDPGLFNITPVEAMWMDPQQRKLCEVVYEAFESGGISLDAIAGSRTGVFAASFTADWQQMSMKEPSFRHTMAATGVDPGILSDRISYVFNLNGPSIVCNTACSSSIYALHNACIALRNDECDGAVVGGTNLVFTIDQQMNTAKIGVLSPRGTCFTFDESADGYGRAEGVGAVYLKRLSDAVRDGDPIRAVLRGSSVNHNGRVSSASISYPGVNGQAYVMADAYKRSGNLDPMLTGYFECHGTGTAVGDPIEVEAIGRAMNHSRRPGVDDKLMIGAVKTNVGHGEAASGLTALIKAVLIVERGIIPPTIGIKKLTSKIKWDEWQVQVPVEPTPFPSHLPMRRVSVNTCGYGGTNAHVIVEEAGSILRLPQTYKFVDNHILSGLSSRTHTPRRAAHRKRPFLLPFSAHDKTSLRQNIVNHGKVAGNYNLLDLSYTLGCRRSTLTSKAFTVASYNTLGDSFENIESSFTFADKKRPQAPTVGFVFTGQGAQWPRMGAELLQYSPNFLQSIRGLDRALDELHDGPEWAIEDLLVEDETISRVHEAEFSQPLCTAVQIGLVDLLSHWGIRPVVTVGHSSGEIAASYAAGLVSAKEAITAAYYRGKVTKDVKKGGAMMAVGLGAEAAELYLASLAGNVVVACHNSPSLVTLSGDDAALQELKTKFEAENIFARFVKTNGKAYHSHYMIPVAKQYEVLFQEARKKSFFDKREKTASSNIRMVSSVTNTIFDENTVIDETYWSANLQSPVLFNQAVHTILKAEEFSDVDLLIEVGPHSAMAGPIKQIKAALKAEKLEYASTLLRGQDSAVQLLKLAGEMYLRSYPLQMERVTAAYASEAKGGKGSVIVDLPHYSWNYSRQFWPESRASKEHRHATHPRHDVLGQLVIGASPLEPTWRNVLRIRDLPWLKDHSLGGEAVFPAAGYFSMAVEAITQLNERSGKPVGIDNYVLRDVSIKKALVTPDNDDGIEVITNMRHSIVFGDGWWDFSVSSVDAEGTIKDHMAGSIGINTTDKTRTPRTAPEFTQRATGRAWNQALREVGFDYGPTFQDMEDIRFDGKRYEASSATSIKQTVDESLGESRHALHPAVVDSTLQLSIVAIYAGRTNAMDCGVVPVQVDEVTIWPPTPEQLAAGKASAYAWVDRRGIRSFENSVQMTAGNGEMVMEIVNVRTTSYEAAVPQKDESALLPAPYGEMAWQYDIQALMDTGKANEINPADLASLALFKYPSLKVFHVCVGSHAAHSLLTQNPRAHWTLAIMSGGQEDLEEAKEALTSFPNAHVVGLDLSLEPEEQGLAAGSYDLVLARTDLIDANLHRLAKPNGFIISFVGQKSHMTKVPGPPAAGANGHLPHNVQVVYRKSPGAGVSHAQSSLEGLGWTVKLSKLESFADASNIAAKHVVMLTDFEGPLLSSITQTEFVAIQNVTNTATSLLWVTNGGLLEGEQPEHAMVSGLARSVRAEQASLDFRTIDVDAKSSPLEITRAITRVAQLQYSKIEEVPENEFCLAGGMTYISRLVRNNALNEKFSSSAKAQLVNYSPKDRISGKVVHGKVMFEEQVADQNAIKPSHVEVQVQYSGLTRESVLVVTGSDYPTTFSHAIGGVVTKCGEGVTSLKPGDKVVGLNVDKFSSYQEVPANMLQKVTSNDRVEKLVSLLMPYAAALYGLDTLARVAPKETILVLHNTGAIGVAAIKVAEARGATAYIVAKTNEEIDFLSKTLGLPQEQIIQSSVSTVSSQIEKLTNGHGADIVFSAGSAIDSKDATEAWRCIGRFGRFVDAGRKDVLSRNALDTFPTRRGALYMPFDMLDLLEARPEAVATLIPVILDMFKNSSIVPPGVIETVNLGDLDQAVSAYSDACGAVMHVIRYTESPIRIIPRQRAKLSFSPDVTYLLVGCLGGLGRSLTSWMMESGARRFAFLSRSGTDAPSAARLLRDIEAAGAIVQVVRGDATNRGDVVRAVQEIPTAHPIKGVVHAAMVLRDALFHSMTFDSWKTSVEPKVVGAMNLHSVLANTDLDFFLMTSSVSGVLGTPGQGNYAAANSYLDSLARHRMRQGQSAVASVIPMVLGVGVVSENTELEDNLRRKGMYGIDEEHLLQSFEASMVASSTKERLGLDHVVIGLDPVLLQKAVNDQTATDSFWVEDVRFNHVVHAMSSSKSAASGGHSQNILGAIKSAASPADAVGLVTSHLTEKLSRMLLLPEDSIDALSGSIASYGVDSMIGAELRNWIFKEYRLDIPFQQLLAATLTINKFAKQVCESAGVVVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYL1</accession>
    <name>E3QYL1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11093</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697405">
        <property type="protein sequence ID" value="EFQ35949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099969.1">
        <property type="nucleotide sequence ID" value="XM_008101778.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYL1"/>
    <dbReference type="STRING" id="645133.E3QYL1"/>
    <dbReference type="GeneID" id="24416458"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11093"/>
    <dbReference type="eggNOG" id="ENOG502RUI4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2722079_0_0_1"/>
    <dbReference type="OrthoDB" id="4851009at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180949" evidence="1">
        <location>
            <begin position="19"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="72" mass="7997" checksum="C229BB7A36C86DD4" modified="2011-01-11" version="1">MKFTNTAAILVLSPMVVAAPLSSTEKRKPEASKQYFHLAGDVLDKREPKPKAAKQYFHLAGDVLDKRTEIAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYM7</accession>
    <name>E3QYM7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">WD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_11109</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat MET30/SCONB/SCON-2 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697405">
        <property type="protein sequence ID" value="EFQ35965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099985.1">
        <property type="nucleotide sequence ID" value="XM_008101794.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYM7"/>
    <dbReference type="STRING" id="645133.E3QYM7"/>
    <dbReference type="GeneID" id="24416474"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11109"/>
    <dbReference type="eggNOG" id="KOG0274">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_103_1_1"/>
    <dbReference type="OrthoDB" id="5580488at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043224">
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        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="3 6" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="F-box" evidence="8">
        <location>
            <begin position="128"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="302"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="342"/>
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        </location>
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    <feature type="repeat" description="WD" evidence="6">
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            <begin position="382"/>
            <end position="421"/>
        </location>
    </feature>
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        <location>
            <begin position="421"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="547"/>
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            <begin position="589"/>
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            <begin position="612"/>
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            <begin position="25"/>
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    </feature>
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            <begin position="32"/>
            <end position="42"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZ97</accession>
    <name>E3QZ97_COLGM</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11326</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008102014.1"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="5397183at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
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        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
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        <location>
            <begin position="118"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="281" mass="31452" checksum="212521F875140130" modified="2011-01-11" version="1">MEDGTLDEYSIGDSDEEDMAMLLESADGNPSKPSPSHFPVTIDQGPRSTGSFDLKLHSSSSDVSHDEASKINFLEPDFLDEDIDWDTFTACEKDATRSPETGMLVDAASMQETSSPSSPTPIIRPPVPPKMRDRSVVVGLSSTTMMRTCFRIGELLNAHAKCTRDKQDVVLELFARVRYSIRETTTRVQHFDLRDLFTDRQPFLSGTFREWKLNSSLDHDSRSFLGLSGQNKLCRCVCKLSNARETTIGRSAMILSIRETTWDEIFWALRIVARDAPSDSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZT3</accession>
    <name>E3QZT3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11516</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697421">
        <property type="protein sequence ID" value="EFQ36371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100391.1">
        <property type="nucleotide sequence ID" value="XM_008102200.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZT3"/>
    <dbReference type="GeneID" id="24416880"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11516"/>
    <dbReference type="eggNOG" id="ENOG502RVMB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078024_0_0_1"/>
    <dbReference type="OrthoDB" id="2332199at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="258" mass="28346" checksum="F677516F8301BAA5" modified="2011-01-11" version="1">MGVSLSTAQWLAPLSFVIDFVAQNYGMFSTPNMKDVHDANLSFWSPQPFFIAGFFFPQQLFQVAWLWRLYKADTKIEPMDADVGTMVDFAPFYAIGNFCIATWMIFWNSSDLKTSNVFVIINSFAQLYFIFNRLPPMNTKSVNSVLTHVVAKTFAGIGVLDLLHNGSVAYFVHQQPSTVVKVLTGVGFGLLASVSDWIFGGCLVYDLIALSVGQSAYGNAQWSRLLGIYAGGAAAIVSARNIMKPPYVSQPAAGYSPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3R037</accession>
    <name>E3R037_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C2H2 type master regulator of conidiophore development brlA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_11620</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697426">
        <property type="protein sequence ID" value="EFQ36475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100495.1">
        <property type="nucleotide sequence ID" value="XM_008102304.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R037"/>
    <dbReference type="STRING" id="645133.E3R037"/>
    <dbReference type="GeneID" id="24416984"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11620"/>
    <dbReference type="eggNOG" id="KOG1721">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002678_42_18_1"/>
    <dbReference type="OrthoDB" id="3437960at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000125">
        <property type="entry name" value="Putative zinc finger protein 143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR PROTEIN YY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003:SF19">
        <property type="entry name" value="YY2 TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="17"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="47"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00044085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ36475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="83" mass="9592" checksum="63CD5CC26EFFB33A" modified="2011-01-11" version="1" fragment="single">KDRLKRHCCIHTNKRPYRCSTPCCDKSFTQILHLNRHNPTHTGEKSYQCQHSGCGGGHSFRCSRFPPDPSSLARHRHVHTGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>E3R097</accession>
    <name>E3R097_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_11670</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697436">
        <property type="protein sequence ID" value="EFQ36535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100555.1">
        <property type="nucleotide sequence ID" value="XM_008102364.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R097"/>
    <dbReference type="GeneID" id="24417034"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11670"/>
    <dbReference type="HOGENOM" id="CLU_1283171_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ36535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="215" mass="24303" checksum="788F494F7249C9CE" modified="2011-01-11" version="1">MALPLTPEPLDFSKKVNRRLCCRQVRRRCDELMRTDDPEGLAKHVDYVKPVHKMLKYYGWRDKGKAGEEAWIPTWNSRGQFKAWISTNSKNLLISIHLAEHFSVIRLSIRFPGLRQSLLSSCCPLLSSTSFPLSPENHDGDNEGQIESRVQSFELCFHADFAGTPDPISLHLYSSSSSPVLSTSSIISNASSVVLYRYKPAPLLKTPPPPFYELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0K3</accession>
    <name>E3R0K3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11786</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697452">
        <property type="protein sequence ID" value="EFQ36641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100661.1">
        <property type="nucleotide sequence ID" value="XM_008102470.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0K3"/>
    <dbReference type="GeneID" id="24417150"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11786"/>
    <dbReference type="HOGENOM" id="CLU_2049530_0_0_1"/>
    <dbReference type="OrthoDB" id="1606438at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="120" mass="13306" checksum="FD197154C3660A2C" modified="2011-01-11" version="1">MGSTGHSELLRLAESVLQATTTIVHHLQDTNQQEPSFDQNSVAIQGSDGSEAARILLNDAARSLTRLVNGPVNEFRSFFMTQYDLAAWQAALEFGLFGHVPLMIIMMMILFNARYVHLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0Z6</accession>
    <name>E3R0Z6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11931</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697536">
        <property type="protein sequence ID" value="EFQ36784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100804.1">
        <property type="nucleotide sequence ID" value="XM_008102613.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0Z6"/>
    <dbReference type="GeneID" id="24417294"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11931"/>
    <dbReference type="eggNOG" id="ENOG502RPPR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_842009_0_0_1"/>
    <dbReference type="OrthoDB" id="5090566at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="330" mass="37045" checksum="02B51BC07C4BF7A4" modified="2011-01-11" version="1">MSNIFIKYPPLVGLYNRWAGDPIEYGAAALLQNIVIIFFKIEDSFCPAFEQPPDLGSRRNYRIDVLIFEHNIMYSAPGLLVPRLLLEMKGGGGSSKAVESQALANARASIQQYSLVGLFVQTVLGIERALYFRFWWMDSVSLQLQPLDGGPKSGSRDGRSAYVELSTEGGNKLESYYNQVKSGTPIIPTEEHGQDPLDPLAQEVDHSADNLPNETLGYEGDAMMADIAAQQGGVSESEPEEMDQEAGAGPSQAPQGTGQSRNATPKRIEITYESHTLRKDKFLFRKHKKGRIHSTEIEDWDVKRTRDGEVWTWKKDKKYWGYRPHGMSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3R142</accession>
    <name>E3R142_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_11977</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697601">
        <property type="protein sequence ID" value="EFQ36830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100850.1">
        <property type="nucleotide sequence ID" value="XM_008102659.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R142"/>
    <dbReference type="GeneID" id="24417340"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11977"/>
    <dbReference type="HOGENOM" id="CLU_2661161_0_0_1"/>
    <dbReference type="OrthoDB" id="2328572at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050675">
        <property type="entry name" value="OAF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31069:SF31">
        <property type="entry name" value="MONODICTYPHENONE CLUSTER TRANSCRIPTION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31069">
        <property type="entry name" value="OLEATE-ACTIVATED TRANSCRIPTION FACTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00755">
        <property type="entry name" value="AFLATOXINBRP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="13"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ36830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="76" mass="8397" checksum="81F5FF5BF786D62C" modified="2011-01-11" version="1" fragment="single">KMNSIKTQKRRSSCDACGASKLRCDRSQPACGRCVALKQNCVYGISRYKGRPKKNLWDISQGSPLKTSTSPSSEEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3CUA5</accession>
    <name>E3CUA5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NADH-ubiquinone oxidoreductase chain 6</fullName>
            <ecNumber evidence="1">7.1.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_18010</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <geneLocation type="mitochondrion" evidence="2"/>
    <reference evidence="3" key="1">
        <citation type="submission" date="2010-09" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Glomerella graminicola strain M1.001.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Vaillancourt L."/>
                <person name="Ma L.-J."/>
                <person name="Thon M."/>
                <person name="Dickman M."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Koehrsen M."/>
                <person name="Alvarado L."/>
                <person name="Berlin A."/>
                <person name="Borenstein D."/>
                <person name="Chen Z."/>
                <person name="Engels R."/>
                <person name="Freedman E."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Hepburn T."/>
                <person name="Howarth C."/>
                <person name="Jen D."/>
                <person name="Larson L."/>
                <person name="Lewis B."/>
                <person name="Mehta T."/>
                <person name="Park D."/>
                <person name="Pearson M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Walk T."/>
                <person name="White J."/>
                <person name="Yandava C."/>
                <person name="Haas B."/>
                <person name="Galagan J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2010-09" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Vaillancourt L."/>
                <person name="Ma L.-J."/>
                <person name="Thon M."/>
                <person name="O'Connell R."/>
                <person name="van Themaat E.V.L."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Alvarado L."/>
                <person name="Berlin A."/>
                <person name="Chen Z."/>
                <person name="Freedman E."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Mehta T."/>
                <person name="Pearson M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="White J."/>
                <person name="Yandava C."/>
                <person name="Haas B."/>
                <person name="Galagan J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29091"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.1.1.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I subunit 6 family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.2" evidence="1"/>
    <dbReference type="EMBL" id="CM001021">
        <property type="protein sequence ID" value="EFQ24851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100891.1">
        <property type="nucleotide sequence ID" value="NW_007361658.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3CUA5"/>
    <dbReference type="STRING" id="645133.E3CUA5"/>
    <dbReference type="GeneID" id="24417735"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_18010"/>
    <dbReference type="eggNOG" id="ENOG502S14H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085957_1_0_1"/>
    <dbReference type="OrthoDB" id="10050457at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Mitochondrion MT"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1200">
        <property type="entry name" value="NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001457">
        <property type="entry name" value="NADH_UbQ/plastoQ_OxRdtase_su6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042106">
        <property type="entry name" value="Nuo/plastoQ_OxRdtase_6_NuoJ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33269">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33269:SF17">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00499">
        <property type="entry name" value="Oxidored_q3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0249">Electron transport</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="1" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="1" id="KW-1278">Translocase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <keyword evidence="1" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ24851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="247" mass="27330" checksum="C0C24C4C3DE0DC40" modified="2011-01-11" version="1">MTNLFIIDEIYTSGFKTSALDIVSILAILCAILTIVSKNPIVSVLFLIGLFGMVSSYLILLGLNFIGLSYLIVYVGAVSILFLFILMLINIRVSELQSNTKNSIPLALFITILFNYLIFQFLPYDLAILNNSNHSSALNNVLYHTSFNGISDYNKIFNSFGSNSQISNVAKEGSSDLFFATSSSWDGNLIETSHISSIGNILYTSHSMWLILTSFILLLAMIGAIVITIKQKNKGISSMVEQPFYTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2A0</accession>
    <name>E3Q2A0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Dihydrodipicolinate synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_00345</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the DapA family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089221.1">
        <property type="nucleotide sequence ID" value="XM_008091030.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2A0"/>
    <dbReference type="STRING" id="645133.E3Q2A0"/>
    <dbReference type="GeneID" id="24405710"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00345"/>
    <dbReference type="eggNOG" id="ENOG502QWNS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049343_0_2_1"/>
    <dbReference type="OrthoDB" id="191315at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008840">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00408">
        <property type="entry name" value="DHDPS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128:SF66">
        <property type="entry name" value="4-HYDROXY-2-OXOGLUTARATE ALDOLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="DIHYDRODIPICOLINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="3">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001365-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001365-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ25201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="318" mass="34354" checksum="67919C0D9D4C182C" modified="2011-01-11" version="1">MAPTKSFPAGIHVPSLTWFGDDASQEIDWDVQTKHIEFLVKSGLHGIVLAGTNGEAVTLTNEEKTRLVKTTREVAVKAGRPDLTITMGCGGQSTRTVIEETRLAAAAGADYALVLVPSYFHFAMNEEAIVGFFEELADASPVPVIIYNFPGVVAGLDVNSDMLSRLGRHPNIVGVKLTCGGIAKVARVRAEFDPAEFFALAGQSDWLVPALTVGSNGTITGVANLFPRYCIEIFDLYSAGKLQEASAAQLKLAQMEWAFGKGGINGTKWVVAKSHGYPLTSCHCRRPYPQYTDEKKQAWISALVAPLVEEEAKLNQRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2N4</accession>
    <name>E3Q2N4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6546 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00007</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ24863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008088883.1">
        <property type="nucleotide sequence ID" value="XM_008090692.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2N4"/>
    <dbReference type="STRING" id="645133.E3Q2N4"/>
    <dbReference type="GeneID" id="24405372"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00007"/>
    <dbReference type="eggNOG" id="ENOG502RAIK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029473_2_0_1"/>
    <dbReference type="OrthoDB" id="4688861at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046676">
        <property type="entry name" value="DUF6546"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20183">
        <property type="entry name" value="DUF6546"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6546" evidence="1">
        <location>
            <begin position="253"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ24863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="476" mass="55347" checksum="592928479ACFB12F" modified="2011-01-11" version="1">MDRFCRLPPELRAAVVEHVVDHWRHGDDSDSIADYALVCKEWQAIVERFNFAVLRVTQANLDDFETAMVGSRRGIVRQINLHVELPTYDNDPCEKKETWEDKAENNVCFTRAFYRLFHIMSRWSADDVTSGGIHFTLSISSPSDLRNANFELWQRRRWNIKDIGEKRFADSWIDFVGQDEEFDRVNRLPAVSVIRSFTLSPQNHRALMPAAHADIVARLPGLQEACFDITKDRKKETRKIHFNQFAGSMSNWPITLKSLTMASNTISSWRQIPHEALAEGDSGAKLCERLRSTAQHLKHLNVTNVVRIREFLRPHWPLGADDTEPFLAHRPYYPEFWHLETLYISYGSIWYNTEWHKQGDNINESSELVEFRQNVSLAAARMAYTMPRLKHMTVKQRPLMWAGKHELEYRVEEANEKPSKATLTWTSTFDFKPWERTVEAWTEVAARYAGVKLESRVKSAAWHTDGRAPLLPSLTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2W8</accession>
    <name>E3Q2W8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00091</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDC123 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ24947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008088967.1">
        <property type="nucleotide sequence ID" value="XM_008090776.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2W8"/>
    <dbReference type="STRING" id="645133.E3Q2W8"/>
    <dbReference type="GeneID" id="24405456"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00091"/>
    <dbReference type="eggNOG" id="KOG2983">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034402_2_0_1"/>
    <dbReference type="OrthoDB" id="360540at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905143">
        <property type="term" value="P:eukaryotic translation initiation factor 2 complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009772">
        <property type="entry name" value="CDC123"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15323:SF6">
        <property type="entry name" value="CELL DIVISION CYCLE PROTEIN 123 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15323">
        <property type="entry name" value="D123 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07065">
        <property type="entry name" value="D123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="87"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="101"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ24947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="423" mass="47608" checksum="472949B60F578484" modified="2011-01-11" version="1">MPSLEGLTGGQPTLDAVNNTTAQNPEELTFPPVAKDHILNCSYDSWFPKYRTVSIRSRIIKLSADFVQYIRDDGIILADEDNVLAEEDEGEWSASSNTADAPRRNRHLEGDSSDDEPEADSRPPNERFPEIHQEIKDIINELGGAVAPKLNWSAPKDAAWISTHQNTLKCTSPNDIYLLLKSSSFVSHDLEHAFKDTVSSTSNRPFQPVLVLRPFFAPNPALEFRCFVKHRALIGVCQRDWNYYPFLDGLRPALVSKITDFFEDRLRFTFPDGSFIFDVYVPCDSNSYDELGKVRLIDINPWAPRTDSLLFSWVELLEFKVPKPMLGSVVNEEEQLEGSAADETTDEEDADELVPELRLVEKDNPVAFNFSTPQYSAHKLPKEVVDTSLSGEGGLREFVQRWKEMTEADGGGDVWENSATAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2W9</accession>
    <name>E3Q2W9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00092</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ24948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008088968.1">
        <property type="nucleotide sequence ID" value="XM_008090777.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2W9"/>
    <dbReference type="STRING" id="645133.E3Q2W9"/>
    <dbReference type="GeneID" id="24405457"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00092"/>
    <dbReference type="eggNOG" id="ENOG502SWSC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047032_0_0_1"/>
    <dbReference type="OrthoDB" id="4174112at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022190">
        <property type="entry name" value="DUF3716"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12511">
        <property type="entry name" value="DUF3716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="349"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ24948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="379" mass="40285" checksum="6FB0D286BFB7CD55" modified="2011-01-11" version="1">MSARGGSRPPPRGRPNKVTKPAGGLKRDAHGRQSRHSSVAADQLEQLAHDAEAEAEHEDDDEITVPPPPGTSSHHQHQHQHQHQHQQHQQHHHPNPFDLAAAGILANGPPGSVPGAEADIHPDLHSLPAQFAMEAPMGTHGAGGLSRTAEDLASESGYGQLVIDSALAKRLANNEGQRLAVQRRQDQTLNLKRRSNVEALLAHVSGQEAHSPCKSCHKGYGPWNGCVVVSGQMCGSCANCWFNASGSRCSFHENNLPQHMPAIQLQPVPQVSANTSFAGTAPMAPGMAPAGPSFGQPGADPTVAQFVKDVLDRAMAEARSDNPHVRFQLRIETAARQLALASAEYAEFLAQQGGHDPSQHPDPESSVPEAPMGEDDNGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3L7</accession>
    <name>E3Q3L7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-glucuronidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00763</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089639.1">
        <property type="nucleotide sequence ID" value="XM_008091448.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3L7"/>
    <dbReference type="STRING" id="645133.E3Q3L7"/>
    <dbReference type="GeneID" id="24406128"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00763"/>
    <dbReference type="eggNOG" id="ENOG502QW09">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022148_0_0_1"/>
    <dbReference type="OrthoDB" id="2796951at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052974">
        <property type="entry name" value="GH79_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031728">
        <property type="entry name" value="GlcAase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36183">
        <property type="entry name" value="BETA-GLUCURONIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36183:SF2">
        <property type="entry name" value="BETA-GLUCURONIDASE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16862">
        <property type="entry name" value="Glyco_hydro_79C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-glucuronidase C-terminal" evidence="1">
        <location>
            <begin position="455"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="586" mass="62498" checksum="3021E303ED0F81A3" modified="2011-01-11" version="1">MPASIAIRSLGSILSHEIRCLFTAFPPSYGLLAWAGFLPHIVDALAVTRDMAPIAVPGPEEASAVFDAFVSYSLEFAFFPDFAGNASAPNTFSDNLLANIGALQGVRPYIRVGGNTQDYALYDESLPYAVNGTYDFDRSRDYPTTVYIGPSFFESYGTFADTKFTHGFNLGLGANRSEGWETLKATVPLACRAIGKDNLDVWEYGNEPDLYSTSAQGPVRPPSWDEAAYVAQWLNGTREIARVLAAACPDFPAPPAFKAPSNGGTANRLRAPAQWAAGLNADANVALFSTHNYISGAESPGVTLQGTLMNHTRTVESVRAHVREYANMTARFGHDAVPPHILGEHNSLYNQGKPGLSNSFGAALWGVDFNLYAASQGIKRSHMHMGTDYRYQSWQPVHTNTTALGTKAPYYGNIAVAAFLAPPSCSSSSSSSSCPPVSVAHIPLGNDGDDGHAAAYAAYHGTALVRILLVDLHAYNSTVNGTGTTPDPDPTREDRATFTHSFAVPPSSWRDGGLAGLRRLRANGSDAVTGVTWDGWSYNHELDGGRPVRLDNVTVGENALVDGGRVVFTVSASEAVVISAPDSGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3W7</accession>
    <name>E3Q3W7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00863</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089739.1">
        <property type="nucleotide sequence ID" value="XM_008091548.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3W7"/>
    <dbReference type="STRING" id="645133.E3Q3W7"/>
    <dbReference type="GeneID" id="24406228"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00863"/>
    <dbReference type="eggNOG" id="KOG1454">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_50_3_1"/>
    <dbReference type="OrthoDB" id="2498029at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050266">
        <property type="entry name" value="AB_hydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798:SF33">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G14860)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="27"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="285" mass="29955" checksum="8C06621455696418" modified="2011-01-11" version="1">MTTSSYFTAPSGHTIHFLHSGSISGGLLVCLHGLGGSTETFLPLLPALPKSFNIVLVDFPGFGKSVLNKAAKPITVTSTVLDIECLISSIKESAGTSHSEKIIFIGHSFGAIVALHYAAKHSDAVAGLALLGAGRAAGHIPAVKQRMLQLASNARNLGIDFAANSAAESNFYTDTPERSASPSARESVRKAVAASDTESYAQVCEALVDLYHTDPDYSSIECPTVFIPGDKDMISPTDRSNELSKLMGGESWVVTVKSGHQQALEDPEGVGEALVQLFARIEGSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3Z7</accession>
    <name>E3Q3Z7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00893</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089769.1">
        <property type="nucleotide sequence ID" value="XM_008091578.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3Z7"/>
    <dbReference type="GeneID" id="24406258"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00893"/>
    <dbReference type="eggNOG" id="ENOG502R6PT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1539921_0_0_1"/>
    <dbReference type="OrthoDB" id="10508603at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="174" mass="19587" checksum="C194BD7A68A2953D" modified="2011-01-11" version="1">MSLSTPYSYSQFSHEMELDDPVAYSPSFSSPQTLPSEMDLDEEPSSYSSSEAFQTPFPSEKRGSYHPSCSNGRPKSPFTGERSQKCQRSKNNKANTETKVRSHRSGEKQVGKSENQKQKPESAEKPKPKGQQRKQQPRQLKQNRGLQRAGAKEKKPVNPFLVSRASVNSQGQRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q479</accession>
    <name>E3Q479_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_00535</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089411.1">
        <property type="nucleotide sequence ID" value="XM_008091220.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q479"/>
    <dbReference type="STRING" id="645133.E3Q479"/>
    <dbReference type="GeneID" id="24405900"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00535"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_0_3_1"/>
    <dbReference type="OrthoDB" id="5376138at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000088">
        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF13">
        <property type="entry name" value="MULTIDRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12550)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="337"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="375"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="417"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="445"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="491"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="515"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="106"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="564"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="44"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="612"/>
            <end position="623"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ25391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="631" mass="69720" checksum="F5077ABC0F8ACAA8" modified="2011-01-11" version="1">MPNTRFAEEPPQVINQADLELANEKLESRDEPAADADVSNSEHASSKELGHGTDHSEHEANRIAGNANGNGAKLEKLGTYDKYEITEDDCYNELGFGFPKWKKWYILTVIFWVQVSMNFNTSLYSNAIPGISEEFNVSAQAGRCGAMIFLVLYAFGCELWAPWSEEFGRWPVLQLSLALVNVWQLPVALAPNFATIMVGRALGGLSSAGGSVTLGMIADLFESDDQQYAVAYVVFSSVGGSVLGPIVGGFTEAYLNWRWSIWVQLIFGVAVQALHFFTVPETRTTIMMNRIAKRRRKEGNPNIWGPDELVPFKDRFSVKEILSTWVRPFKMFLTEPIVLVLSLLSGFSDALIFMFIQSFVLVYQQWNFDTVQVGLAFIPIGIGYVLAWLLFIPAIRRNIKEREAKPNDDRAQYESRLWILLYTAPCLPIGLIGFAWTIQGPPIHWIGSMVFAAIVGIANYAIYMATIDYMLCAYGPYSASATGGNGWARDFLAGVLTVPATPFFTNIGAASGKNLEYACTILFCISFVLVVAVYVIYWKGPALRARSPFAQKLAGARDDVGGRRVSYAPGERPASAASGADQPARPGYQRSYSQQNRFFGENRVTPRGTPRGTPSASRANSFVGTRRTAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4G2</accession>
    <name>E3Q4G2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">mitochondrial processing peptidase</fullName>
            <ecNumber evidence="5">3.4.24.64</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Beta-MPP</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">GLRG_00618</name>
    </gene>
    <organism evidence="19">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalytic subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins. Preferentially, cleaves after an arginine at position P2.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of N-terminal transit peptides from precursor proteins imported into the mitochondrion, typically with Arg in position P2.</text>
            <dbReference type="EC" id="3.4.24.64"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the peptidase M16 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.64" evidence="5"/>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089494.1">
        <property type="nucleotide sequence ID" value="XM_008091303.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4G2"/>
    <dbReference type="STRING" id="645133.E3Q4G2"/>
    <dbReference type="MEROPS" id="M16.003"/>
    <dbReference type="GeneID" id="24405983"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00618"/>
    <dbReference type="eggNOG" id="KOG0960">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009902_4_2_1"/>
    <dbReference type="OrthoDB" id="10251424at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006627">
        <property type="term" value="P:protein processing involved in protein targeting to mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000002">
        <property type="entry name" value="Mitochondrial-processing peptidase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000001">
        <property type="entry name" value="Mitochondrial-processing peptidase subunit beta, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050361">
        <property type="entry name" value="MPP/UQCRC_Complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001431">
        <property type="entry name" value="Pept_M16_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851:SF149">
        <property type="entry name" value="GH01077P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851">
        <property type="entry name" value="METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00143">
        <property type="entry name" value="INSULINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M16 N-terminal" evidence="16">
        <location>
            <begin position="52"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 C-terminal" evidence="17">
        <location>
            <begin position="204"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EFQ25474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="476" mass="52803" checksum="D81F8F57FEE1C730" modified="2011-01-11" version="1">MASRRLALNLSQGLRSRAALSRASPITRGFATPSNSPFGKTQTTTLKNGLTVATDYSPFAQTSTVGVWIDAGSRAETDETNGTAHFLEHLAFKGTTNRTQQQLELEIENMGGHLNAYTSRENTVYFAKAFNADVPQTVDILADILQNSKLEESAIERERDVILRESEEVEKQMEEVVFDHLHATAFQHQPLGRTILGPRENIRDITRTELTNYIKNNYTADRMVLVGAGGIPHEKLVELAEKNFSGLPTTGPNTQAYQLSKQKADFIGSDVRVRDDNIPTANIAIAVEGVSWNDDDYYTALVAQAIVGNYDKALGNAPHQGSKLSGFVHKHDIANSFMSFSTSYSDTGLWGIYLVTDKHDRIDDLVYFAQREWMRLSRNVSEAETERAKAQLKASILLSLDGTTAIAEDIGRQLITTGRRASPGEIERTIDAITEKDVMDFASRKLWDQDIAISAVGSIEGLFDYSRLRATMKPKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4Q1</accession>
    <name>E3Q4Q1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SMP-30/Gluconolaconase/LRE-like region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_01210</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ26066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090086.1">
        <property type="nucleotide sequence ID" value="XM_008091895.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4Q1"/>
    <dbReference type="STRING" id="645133.E3Q4Q1"/>
    <dbReference type="GeneID" id="24406575"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01210"/>
    <dbReference type="eggNOG" id="ENOG502RZSA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036110_1_3_1"/>
    <dbReference type="OrthoDB" id="423498at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052988">
        <property type="entry name" value="Oryzine_lactonohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013658">
        <property type="entry name" value="SGL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47064">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G08990)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47064:SF2">
        <property type="entry name" value="SMP-30_GLUCONOLACTONASE_LRE-LIKE REGION DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08450">
        <property type="entry name" value="SGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMP-30/Gluconolactonase/LRE-like region" evidence="1">
        <location>
            <begin position="127"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="332" mass="36206" checksum="C1D90ABEFC3A505A" modified="2011-01-11" version="1">MTDNPAFVVYDDRVKKLYGPAPKLEVLHENQDYPFAHEAGVFIERNSTLFVTSNQFTDNSGGRKIQICRIVLPDDGGPAVACEEIHPATVAMANGGVNYLDGVVFCSQGTMDAPGGLVFMEAEPPYETRMMVSSFHGRAFNSVNDVVAHGDGSLWFTDPIYGHEQGIRPPPQLPNQVYRYDPIHGSIRAMADGFGRPNGICFSPDEKIVYITDTDWIHGDGSTDLTRASTIYAFDVVSYSGEPFLTNRRLFSMADTGIPDGIKCDVHGNVYSGCGDGVNIWSPGGVLLGKILVEGGAANFCFGRNGEIFILNEHRLWRAKLADETKGALLCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q544</accession>
    <name>E3Q544_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_00955</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089831.1">
        <property type="nucleotide sequence ID" value="XM_008091640.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q544"/>
    <dbReference type="STRING" id="645133.E3Q544"/>
    <dbReference type="GeneID" id="24406320"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00955"/>
    <dbReference type="HOGENOM" id="CLU_2904060_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ25811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="62" mass="6976" checksum="4048F90FB84424AA" modified="2011-01-11" version="1">MKTGILRYDNTSTAKPSTTAWAIEPVVPWTVGDPSNGQIGEQFNIDILEHMHWPLRDVDLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6G3</accession>
    <name>E3Q6G3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_01555</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090431.1">
        <property type="nucleotide sequence ID" value="XM_008092240.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6G3"/>
    <dbReference type="STRING" id="645133.E3Q6G3"/>
    <dbReference type="GeneID" id="24406920"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01555"/>
    <dbReference type="eggNOG" id="ENOG502SN2C">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141128_0_0_1"/>
    <dbReference type="OrthoDB" id="3924764at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180133" evidence="2">
        <location>
            <begin position="22"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ26411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="106" mass="11375" checksum="81A48CA7FC54082E" modified="2011-01-11" version="1" fragment="single">SRLLMVLGLAGFVAAFPRIQARSDKCPQTICIDGINTQCSTRWGGCYDRCKPDTRPTMPPCNPTPGPPSITKPPSTPTAKPTPGDSCSTRTICRDFIDDCGHMYGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7Y1</accession>
    <name>E3Q7Y1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02164</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ26993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091013.1">
        <property type="nucleotide sequence ID" value="XM_008092822.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7Y1"/>
    <dbReference type="GeneID" id="24407529"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02164"/>
    <dbReference type="eggNOG" id="ENOG502S4CM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058475_0_1_1"/>
    <dbReference type="OrthoDB" id="408973at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025870">
        <property type="entry name" value="Glyoxalase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40265">
        <property type="entry name" value="BLL2707 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40265:SF1">
        <property type="entry name" value="GLYOXALASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13468">
        <property type="entry name" value="Glyoxalase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyoxalase-like" evidence="1">
        <location>
            <begin position="14"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="288" mass="31432" checksum="BE4296FD1D3B1335" modified="2011-01-11" version="1">MASSADQASNTPLLDHIVILVPHQVLASLPSWISSEFTIFTGGRHADGLTENKLVIFADGTYLELISFVEGISQEERLKHKWGPKPDGTVIDWAYSLKDESGFSEIQKRVRAAQSIAAYDDPVPGGRIRPDGEELKWAVALPAGVGTGSGADVERGELPFWCFDRTPRELRVPNHVAENIKHPNGSLGVHSLWVDVRREEFKKAYAGINDRPAEGENGGQWTFDVPVRQFEDPRYLFVATISGEQEPRQSIRLALYTEAGTQKRSIGGDLGGGVSVSIDLVPISGASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7Y5</accession>
    <name>E3Q7Y5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_02168</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ26997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091017.1">
        <property type="nucleotide sequence ID" value="XM_008092826.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7Y5"/>
    <dbReference type="STRING" id="645133.E3Q7Y5"/>
    <dbReference type="GeneID" id="24407533"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02168"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1185750_0_0_1"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF22">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="1"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ26997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="219" mass="24202" checksum="45A246807E86786F" modified="2011-01-11" version="1">MPLIIQAFSGIAWVAGYFTYYLQLAGYSTSMSYKLQIAQPVLPIVGNLMAAAVIDKIGQRNLTFYSLVVLTAFLLIAGGLGTGTTQPMIKGTVAFILLYSWWYNVSIGSSAFSLLAKTSTSRLRAKTVAIGYASQNCINVMWQFVVPYLFSPDKANLGAKLSFIFGGLCFFSLLYLWYFQPETGGRSYEELDEMLAKGVPARKFKTYKTTVQMRNETGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q826</accession>
    <name>E3Q826_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF5672 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_02209</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091058.1">
        <property type="nucleotide sequence ID" value="XM_008092867.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q826"/>
    <dbReference type="STRING" id="645133.E3Q826"/>
    <dbReference type="GeneID" id="24407574"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02209"/>
    <dbReference type="eggNOG" id="ENOG502QW4V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048589_0_0_1"/>
    <dbReference type="OrthoDB" id="10025998at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043729">
        <property type="entry name" value="DUF5672"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18922">
        <property type="entry name" value="DUF5672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5672" evidence="2">
        <location>
            <begin position="95"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ27038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="409" mass="45900" checksum="6C95C1803343D9D2" modified="2011-01-11" version="1">MIKAELKSRLDEARQKIPKIKVDWEPATDPRAKYNASKLALIIEPRPIPHLVPQLLHMTSVVPPDWRFLFIGSKKSVVSVGRSYGIKHQQVIGKLDLMVLPDPWKINTKEHVFRLLTDVRFYNEFLPEVEWILKFESDSILCSNSPRSLNEWLGWSWAGAPRTPDDRFSGNGGLSLRRVSSIKRVLEFQERYNDTEPEDEWFGKRLWIMKGEKVAHGNKGVLAVEDVYLEKPMGYHVRDGGNSLSDAVWKNPQQRKKIFNYCPELSIIMDMKLERERCDDDNGEGGLGPTDAEKKKAEEEAKKAAEEEAKKAVEEAKKAAEEEAKKAEEKKKQKEAEEKAAEEGVKSKMESSPTQSDSGGTSSITSEEIAELLRQKDASKGGESTGLYADDALGKAIASGSQSGGKEQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8C2</accession>
    <name>E3Q8C2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein L19</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_02305</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL19 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091154.1">
        <property type="nucleotide sequence ID" value="XM_008092963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8C2"/>
    <dbReference type="STRING" id="645133.E3Q8C2"/>
    <dbReference type="GeneID" id="24407670"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02305"/>
    <dbReference type="eggNOG" id="KOG1698">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076387_0_1_1"/>
    <dbReference type="OrthoDB" id="432645at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.790:FF:000007">
        <property type="entry name" value="Mitochondrial ribosomal protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001857">
        <property type="entry name" value="Ribosomal_bL19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038657">
        <property type="entry name" value="Ribosomal_bL19_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15680:SF9">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL19M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15680">
        <property type="entry name" value="RIBOSOMAL PROTEIN L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01245">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ27134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="219" mass="24793" checksum="CC11950DB9C9E34F" modified="2011-01-11" version="1">MNVSCLRRPIGCLKTALRQTRHQRLLTRSMATTPAAEQPPASTPSLSPSVKPSYFGPRDKPTFAVYPPLPSIRHTHKNPMPALDAQQRAKLDPTGARTRLFDPARPDAAKVGDVLMVTTKSGEPFSGVCMSIRRRGVDTAILLRGQLMKVGVEMWYKIYSPTVIGIDIVWRRPKRARRARLTYLRKPKHDMGSVDHLVFAWKKERYGMRNKGKQFGTRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8V4</accession>
    <name>E3Q8V4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Heterokaryon incompatibility protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_01963</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091488.1">
        <property type="nucleotide sequence ID" value="XM_008093297.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8V4"/>
    <dbReference type="STRING" id="645133.E3Q8V4"/>
    <dbReference type="GeneID" id="24407328"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01963"/>
    <dbReference type="HOGENOM" id="CLU_1440954_0_0_1"/>
    <dbReference type="OrthoDB" id="4825093at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ27468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="188" mass="20935" checksum="CA6019414C421882" modified="2011-01-11" version="1">MPLYQDEEDNAIFQAFVQDYTTKVIRSCRLERARASYNGLCFSDQTRGWAFSEDTENASLAVARACCCAAVRKELPGMQTGELVQFTGTGGNVGFASSEARIERGDRIIAFRDCHVGFVVRSLPGSSCLQIISVADVETAPRRKRDVGELEGHRPPPFYSPMEDPECEKAYVLMDFRTLQQLTAGVEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q933</accession>
    <name>E3Q933_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">MFS general substrate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_01707</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091232.1">
        <property type="nucleotide sequence ID" value="XM_008093041.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q933"/>
    <dbReference type="GeneID" id="24407072"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01707"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_927518_0_0_1"/>
    <dbReference type="OrthoDB" id="6730379at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF35">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="203"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ27212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="300" mass="33652" checksum="8F5B99237DD7C665" modified="2011-01-11" version="1">MILAQRFLNERVISVIVALWGLCQILTTTYTNYRGLYAQGFCLGLLESGISPMLMLIVGSWYKKDEQASSMGIWYNCTGYVAIFSPLINCGFGKLGSIMPSWRHIFYIISAITIIQGLLLFIIPPPNPIRPKGFSEREQHISVARLRSNNSGVHNTHSKMERVSELGLDPRFWLAYAFTFLCIIANGPISTFVPIIINDFGFSTLNSLLLTMPVAGVLGLVYRFVCTWQNNKRDKAGIVEGYDHAYKDDLTDLKLQRVSNFERDVSSSNDLAFAFELFSASRACLLVLYEIASTEAISLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q969</accession>
    <name>E3Q969_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_01743</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091268.1">
        <property type="nucleotide sequence ID" value="XM_008093077.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q969"/>
    <dbReference type="STRING" id="645133.E3Q969"/>
    <dbReference type="GeneID" id="24407108"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01743"/>
    <dbReference type="eggNOG" id="KOG1167">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_118_2_1"/>
    <dbReference type="OrthoDB" id="10020333at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000775">
        <property type="term" value="C:chromosome, centromeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031431">
        <property type="term" value="C:Dbf4-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000082">
        <property type="term" value="P:G1/S transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902977">
        <property type="term" value="P:mitotic DNA replication preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031573">
        <property type="term" value="P:mitotic intra-S DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001100">
        <property type="term" value="P:negative regulation of exit from mitosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045739">
        <property type="term" value="P:positive regulation of DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903468">
        <property type="term" value="P:positive regulation of DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060903">
        <property type="term" value="P:positive regulation of meiosis I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905263">
        <property type="term" value="P:positive regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905342">
        <property type="term" value="P:positive regulation of protein localization to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904968">
        <property type="term" value="P:positive regulation of spindle attachment to meiosis I kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006279">
        <property type="term" value="P:premeiotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031503">
        <property type="term" value="P:protein-containing complex localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd14019">
        <property type="entry name" value="STKc_Cdc7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167:SF23">
        <property type="entry name" value="CDC7 KINASE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167">
        <property type="entry name" value="OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="89"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="123"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="290"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="464"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="41"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="291"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="475"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ27248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="493" mass="56409" checksum="2450D5C035B0251E" modified="2011-01-11" version="1">MAMATATRKRSREAFEIHQDPPHARTEDTEMMADSEQHTEEVDEQEEPDDDVENDPSDDTSDDDDVVDSGVQRDMDRLQDTFPGFRQKYRLIKRIGEGTFSTVYKAEDLQYDRYDNDWDLEEKDNPAPKWTPPPLKRHGSHTSTSREPRRRARYVAIKKIYVTSSPTRILNELELLHDLRNCAAVCPLITAFRSTDQVIAILPYFRHEDFRDYFRQMKVSDMAIYLRSLFTALKAVHEHKILHRDIKPTNFLYDPQSRRGVLVDFGLAEREGSDSKPCLCRESREIRKQRIATSAASQNGPQQGYPKTDTRPSRRANRAGTRGFRAPEVLFKCTEQTTKIDIWSAGVILLTIMSKRFPFFNSADDVEAMIEIATIFGVKRMRQAGLLHGCMFETNIPTVGNAGFSLGKIILWSTCRTDGGKDGQPGIPLTDEEKLAVDFLENCMELDPARRISAKDALEHEFLKEPLPIQSVEPPFEEDPAEDDDEMDLLEAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9D9</accession>
    <name>E3Q9D9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_01813</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091338.1">
        <property type="nucleotide sequence ID" value="XM_008093147.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9D9"/>
    <dbReference type="STRING" id="645133.E3Q9D9"/>
    <dbReference type="GeneID" id="24407178"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01813"/>
    <dbReference type="eggNOG" id="KOG2404">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022946_0_0_1"/>
    <dbReference type="OrthoDB" id="3345469at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-dep_OxRdtase_2_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014614">
        <property type="entry name" value="KsdD_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009472">
        <property type="entry name" value="PRK12834.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43260">
        <property type="entry name" value="3-KETOSTEROID-DELTA-1-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43260:SF1">
        <property type="entry name" value="KSDD-LIKE STEROID DEHYDROGENASE RV0785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-dependent oxidoreductase 2 FAD-binding" evidence="4">
        <location>
            <begin position="79"/>
            <end position="612"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ27318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="643" mass="70500" checksum="3A927CFBFC8C8BEC" modified="2011-01-11" version="1">MPPHKHYHLRDLVPLPQTPLQTLAALAGIGASAWLLKLIIRHILLRSPAKRSRGSPSSSGPTFAAMNAERKKELLERPVIIVGGGLAGLVAAFELSERGVPTIIIDQENEKNLGGQAFWSLGGIFCVDSKEQRRMGIKDSRELAMRDWFGSAQFDREREDTWPRRWAEAFVNFATDEMEDYVKARGMGFLFNVGWAERGAGMAEGHGNSVPRFHVTWGTGPEVVRVFAEPVKRAAKNGVIQFRFRHRVDEIITDETGRAIGVRGKVLAPDDSPRGVKSNRDVVDDFDIFGSAVAVTSGGIGGNVEAVKAAWPVDRLGPKIPENFVVGVPDHVDGRMIGISEAAGANVINRDRMWHYTEGLQNWDPIWPNHGIRVLPAPSSLWLDATGKRLPPFFFPGTDTLGTLKHICSTGYDYTWFILDQSIIAREFALSGSEQNPDVTGKSVWQLLTRVFGKKGTVPVQNFQKHGKDFVVRDNLADLVQGMNELQRERGGPVLKLEDIRETIELRDGQFDNTYSKDAQAMLINNGRTYWADARSRIAPPHKLLDTKHGPLIAVRMNLLTRKTLGGIETNLESNVMKANGEKFPGLYAAGEAAGFGGGGVHGYNSLEGTFLGGCIFSGRAAGRGIADELLGPAEAKGPKSFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9F2</accession>
    <name>E3Q9F2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">GMC oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_01826</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091351.1">
        <property type="nucleotide sequence ID" value="XM_008093160.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9F2"/>
    <dbReference type="STRING" id="645133.E3Q9F2"/>
    <dbReference type="GeneID" id="24407191"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01826"/>
    <dbReference type="eggNOG" id="KOG1238">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002865_6_3_1"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF138">
        <property type="entry name" value="DEHYDROGENASE PKFF-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180252" evidence="6">
        <location>
            <begin position="20"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="7">
        <location>
            <begin position="326"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="18"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="563"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="607"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="562"/>
            <end position="563"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="608"/>
            <end position="609"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ27331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="627" mass="67619" checksum="24C51B7389525A42" modified="2011-01-11" version="1">MRISYALITFVTSGSLASAAPGKDQTHQHAEHRRQLGTSAGNIGKDATFDYVIVGGGTAGLVMANRLSSQSGVTVAVIEAGTFYQVTNPILGNTPAGDVIFAGSSPLDSNPLVDWNFVTQGQAGANNRRVHYARGKCLGGSSARNFMIYQRGTVQTYQKWADAVGDDSYTWDALLPYFKKSVKFTTPKSSRSPNASAKYNSGAFSAAGGPLDVSYANYAQPFSAYLEPSLNEIGISQTQDFNSGQVMGAQYCSSTIQPNSQKRESSQTSFLDEAIGRSNLKVYQLCLAKRILFDNNKRATGVVVTSNLGLGTFTLQARKEVILSAGAFQSPQLLMVSGIGPRDQLEKFNIPVVAERPGVGKTMEDHVFFGPTWRVKVQTLTRLANDLVYTAAQFAGPYTLLKQGPLTNPIADFLGWEKTPRDLISAEAAAVLDNEFPPDWPEIEYLSAPGYVGDFSNLLTTQPKDGYQYATILGALVAPLSRGTVTLASADTQDLPLINPNWLTDPTDVAVAIATFKRMRQAFASNSMRPVLADNKEYFPGPGIETDEQILQNIRNTVMTVWHASCTCRMGKKDNPMAVVDKDAKVIGVDGLRVVDASSFALLPPGHPQSTVYVLAEKISAEILASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9Q1</accession>
    <name>E3Q9Q1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Forms a complex with the other RRN protein RRN6 and RRN11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_02733</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRN7/TAF1B family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091609.1">
        <property type="nucleotide sequence ID" value="XM_008093418.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9Q1"/>
    <dbReference type="STRING" id="645133.E3Q9Q1"/>
    <dbReference type="GeneID" id="24408098"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02733"/>
    <dbReference type="eggNOG" id="KOG0003">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016553_2_2_1"/>
    <dbReference type="OrthoDB" id="428577at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070860">
        <property type="term" value="C:RNA polymerase I core factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001164">
        <property type="term" value="F:RNA polymerase I core promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042790">
        <property type="term" value="P:nucleolar large rRNA transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048538">
        <property type="entry name" value="Rrn7_cyclin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048540">
        <property type="entry name" value="Rrn7_cyclin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033599">
        <property type="entry name" value="TAF1B/Rrn7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021752">
        <property type="entry name" value="TF_Rrn7_Zf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31576">
        <property type="entry name" value="TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31576:SF2">
        <property type="entry name" value="TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20645">
        <property type="entry name" value="Rrn7_cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20644">
        <property type="entry name" value="Rrn7_cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11781">
        <property type="entry name" value="Zn_ribbon_RRN7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RRN7-type" evidence="10">
        <location>
            <begin position="11"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="Rrn7/TAF1B N-terminal cyclin" evidence="11">
        <location>
            <begin position="91"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Rrn7/TAF1B C-terminal cyclin" evidence="12">
        <location>
            <begin position="244"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF11781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF20644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF20645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ27589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="368" mass="41774" checksum="5BA37825D3CF6355" modified="2011-01-11" version="1">MAPERELHKFPKGERCEFCGSRKWYLESGLRYCAKEGHQLQVCPTGYVEFDLGDEDFGQKGRVSRKQKQVKERVKRVLSGQQARDLYLECLQLILREQILWLVTKKGHAAELETVVRDLWDLRTCGAPTVVHDDSASEREPSLFSSQLDLMLDEPTHARTKRAQSWAPEDGSEWPAPRVMDTLGLCILGCVLLRIPTRIGDIARWARAGSIPYREAYWQLPQEMRDRLPPSYTTPLKAARLAAFDHGELHASVLNLALSYHLNYNMVFPPLNDVLMTLQYVRELGLPASGQDEVNFLVPRLDWEKWRTIMAPALSTGLVQMRVDHTDVTASQILSMGPAELDDYFAHLSLLTDAQGKHPQSIADPLSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9W2</accession>
    <name>E3Q9W2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Histone deacetylase complex subunit SAP30 Sin3 binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_02794</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SAP30 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091670.1">
        <property type="nucleotide sequence ID" value="XM_008093479.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9W2"/>
    <dbReference type="STRING" id="645133.E3Q9W2"/>
    <dbReference type="GeneID" id="24408159"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02794"/>
    <dbReference type="eggNOG" id="ENOG502RZ9X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090091_0_0_1"/>
    <dbReference type="OrthoDB" id="510958at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024145">
        <property type="entry name" value="His_deAcase_SAP30/SAP30L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038291">
        <property type="entry name" value="SAP30_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025718">
        <property type="entry name" value="SAP30_Sin3-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13286:SF23">
        <property type="entry name" value="HISTONE DEACETYLASE COMPLEX SUBUNIT SAP30 SIN3 BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13286">
        <property type="entry name" value="SAP30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13867">
        <property type="entry name" value="SAP30_Sin3_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Histone deacetylase complex subunit SAP30 Sin3 binding" evidence="8">
        <location>
            <begin position="128"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="8"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ27650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="181" mass="20007" checksum="9CC312CB33057940" modified="2011-01-11" version="1">MAPKSSKAAHDDTKSESTAPKEKQTPGSGGHHSNGKLRRVASSTGSQLREVTNANAAADVQVAAKETAQNPAIQWSTFDRETLHAYRREHHLNTPTSFSCSYRQLVLSRPGGIGLHSPTMARKKESRRQSKEQLTLSVRKHFNGLGIQENDIIVDFIHKVRSHAITKSDRHKRSTSTPHDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAH6</accession>
    <name>E3QAH6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">phosphoserine transaminase</fullName>
            <ecNumber evidence="4">2.6.1.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_03008</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>4-(phosphooxy)-L-threonine + 2-oxoglutarate = (R)-3-hydroxy-2-oxo-4-phosphooxybutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:16573"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58452"/>
            <dbReference type="ChEBI" id="CHEBI:58538"/>
            <dbReference type="EC" id="2.6.1.52"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>O-phospho-L-serine + 2-oxoglutarate = 3-phosphooxypyruvate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:14329"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:18110"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57524"/>
            <dbReference type="EC" id="2.6.1.52"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.52" evidence="4"/>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ27864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091884.1">
        <property type="nucleotide sequence ID" value="XM_008093693.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAH6"/>
    <dbReference type="STRING" id="645133.E3QAH6"/>
    <dbReference type="GeneID" id="24408373"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03008"/>
    <dbReference type="eggNOG" id="KOG2790">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034866_0_0_1"/>
    <dbReference type="OrthoDB" id="1703350at2759"/>
    <dbReference type="UniPathway" id="UPA00135">
        <property type="reaction ID" value="UER00197"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004648">
        <property type="term" value="F:O-phospho-L-serine:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009113">
        <property type="term" value="P:purine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000082">
        <property type="entry name" value="Phosphoserine aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000006">
        <property type="entry name" value="Phosphoserine aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00160">
        <property type="entry name" value="SerC_aminotrans_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022278">
        <property type="entry name" value="Pser_aminoTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003764">
        <property type="entry name" value="PRK05355.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43247">
        <property type="entry name" value="PHOSPHOSERINE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43247:SF1">
        <property type="entry name" value="PHOSPHOSERINE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000525">
        <property type="entry name" value="SerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5 13" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0718">Serine biosynthesis</keyword>
    <keyword evidence="7 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="12">
        <location>
            <begin position="9"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Aminotransferase class V" evidence="12">
        <location>
            <begin position="125"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ27864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="425" mass="45832" checksum="EE9231E42C57F4F1" modified="2011-01-11" version="1">MPTRADITYFGAGPALLPTDVLETAAQALLDFNGTGLGIAEHSHRSEIATKIIEEAKADLAAYLDIPADYEILFMQAGGSGEFSATVYNLVGSWVARQRDAVLQRLGVADETDDRVVAELRKVVDEQLKLDYIVTGGWSQKASAEAARLLGPEHVNVAADARKVNDGKFGKIPEEKDWKLSRDAAMVYYCDNETVDGVEFPGFPAALAPNDNGEEGPIVVADMSSNILSRRIPVKNFSAIFFGAQKNLGCTGVTVVVINKSLLAPQPSPALMRKLGLPIAPVVLSYETIAKNNSLYNTLSIFDVYIAGQVLKKLLRTFDNKVDGQQAVADKKAALIYAALEAHPDVYRIVPDKSVRSRMNICFRVTRGGDVDAAEKAFLKESTAQGLTGLKGHRSVGGIRASNYNSIPLEGAEKLAKFIDAFAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAI4</accession>
    <name>E3QAI4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">LSM complex subunit LSM5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">LSM5</name>
        <name evidence="12" type="ORF">GLRG_03016</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">LSm subunits form a heteromer with a doughnut shape.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ27872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091892.1">
        <property type="nucleotide sequence ID" value="XM_008093701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAI4"/>
    <dbReference type="STRING" id="645133.E3QAI4"/>
    <dbReference type="GeneID" id="24408381"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03016"/>
    <dbReference type="eggNOG" id="KOG1775">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076902_6_1_1"/>
    <dbReference type="OrthoDB" id="429711at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990726">
        <property type="term" value="C:Lsm1-7-Pat1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005688">
        <property type="term" value="C:U6 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01732">
        <property type="entry name" value="LSm5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000003">
        <property type="entry name" value="U6 snRNA-associated Sm-like protein LSm5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033871">
        <property type="entry name" value="LSm5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20971">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20971:SF0">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0007">Acetylation</keyword>
    <keyword evidence="3 10" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7 10" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 10" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="11">
        <location>
            <begin position="6"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ27872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="82" mass="8960" checksum="E40FB126E603FE97" modified="2011-01-11" version="1">MAAQLLPLELIDKCVGSRIWVVMKGDKEFSGTLLGFDDYVNMVLEDVTEFDYSGNHTKLSKILLNGNNICMLIPGGEGPVNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QB83</accession>
    <name>E3QB83_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AT hook domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_03265</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ28121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092141.1">
        <property type="nucleotide sequence ID" value="XM_008093950.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QB83"/>
    <dbReference type="STRING" id="645133.E3QB83"/>
    <dbReference type="GeneID" id="24408630"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03265"/>
    <dbReference type="eggNOG" id="ENOG502S09P">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_133918_0_0_1"/>
    <dbReference type="OrthoDB" id="4850225at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017956">
        <property type="entry name" value="AT_hook_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000116">
        <property type="entry name" value="HMGA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02178">
        <property type="entry name" value="AT_hook"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00929">
        <property type="entry name" value="ATHOOK"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00930">
        <property type="entry name" value="HIGHMOBLTYIY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00384">
        <property type="entry name" value="AT_hook"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="73"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="100"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="126"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ28121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="174" mass="18078" checksum="3EBD213DF523D6AB" modified="2011-01-11" version="1">MAPTTPEEEPKKRGRGRPPKADGQKKAAYVPTGRPRGRPKGSGGVKKATAPKPSAGTGRGRGRPRKSDVADATASTVTPKKSTPAKSTGRPRGRPRKSDASTAAPTPTTASANKSKGRKGDVSTKESSPSDSSSASEEEDPALKDVAKSPSDAADSTEEVRRWFPAKVMRGLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QB90</accession>
    <name>E3QB90_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Integral membrane family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_03272</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ28128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092148.1">
        <property type="nucleotide sequence ID" value="XM_008093957.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QB90"/>
    <dbReference type="STRING" id="645133.E3QB90"/>
    <dbReference type="GeneID" id="24408637"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03272"/>
    <dbReference type="eggNOG" id="ENOG502RVVC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_3_4_1"/>
    <dbReference type="OrthoDB" id="4682787at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF96">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="203"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="31"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="286"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="358"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ28128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="426" mass="46187" checksum="93AB7B8D339E9F7A" modified="2011-01-11" version="1">MAEVNLSESNGGALVATAVSFLVLSWFSVLLRCYVRAFMTNGFQVDDWFMVVAQVIFTLSCSFILAGVDNGLGRHNRALSQRQEISALMYQALATATYVLGMLFIKLSIGFFLLRLSTSRVYNWVIHVSLAIVTIWSVVIFFWNTFQCSPIEAQWDYTISNAECVPADAVVAAAYSISVMTILSDWLYALLPIPMVWGIEMTIQAKATVIVILGLGIFASIATLIRLRYLADLGDVADILFTGTDPMVWTLVEPGVAIVASSLVTVRPLLRAWRLTGFASTNRTPGMSGAISGGMRSGTVRSAARPTPRNDPYGAGDVGPTELELGDMGKHEPKPWPKYRIGYTAPFAQFGSKVAGGQIQANSVTPPGRERRRSSDESMYVVEGGKTSDTWRDDRTGSPSVSSADLDGLDAQSQHSGRVGLGGRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCD8</accession>
    <name>E3QCD8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Pre-mRNA-splicing factor RSE1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Pre-mRNA-splicing factor rse1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_03670</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in pre-mRNA splicing and cell cycle control.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the RSE1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092546.1">
        <property type="nucleotide sequence ID" value="XM_008094355.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCD8"/>
    <dbReference type="STRING" id="645133.E3QCD8"/>
    <dbReference type="GeneID" id="24409035"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03670"/>
    <dbReference type="eggNOG" id="KOG1898">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003246_0_0_1"/>
    <dbReference type="OrthoDB" id="436637at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:001143">
        <property type="entry name" value="Pre-mRNA-splicing factor rse-1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000068">
        <property type="entry name" value="Pre-mRNA-splicing factor rse1, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018846">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058543">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050358">
        <property type="entry name" value="RSE1/DDB1/CFT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004871">
        <property type="entry name" value="RSE1/DDB1/CPSF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
        <property type="entry name" value="DNA REPAIR/RNA PROCESSING CPSF FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10433">
        <property type="entry name" value="Beta-prop_RSE1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23726">
        <property type="entry name" value="Beta-prop_RSE1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03178">
        <property type="entry name" value="CPSF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="RSE1/DDB1/CPSF1 first beta-propeller" evidence="12">
        <location>
            <begin position="20"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 second beta-propeller" evidence="13">
        <location>
            <begin position="464"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 C-terminal" evidence="11">
        <location>
            <begin position="856"/>
            <end position="1178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00040134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00055157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00068521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF10433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF23726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ28526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1212" mass="133440" checksum="7E90F77096355974" modified="2011-01-11" version="1">MATTSNMFLYSLTLQPPTNVTQAVLGQFSGTKEQNIITASGSRLTLLRPDPSQGKVITLLSHDIFGIIRSMAAFRLAGSNKDYLILATDSGRITIIEYIPAQNRFQRLHLETFGKSGVRRVIPGEYLACDPKGRACLIASVEKNKLVYVLNRNSQAELTISSPLEAHKPGVLVLSMVALDVGYANPVFAALEIEYTEADQDPTGEAAREAETQLVYYELDLGLNHVVRKWSEPVDPTASLLFQVPGGQDGPSGVLVCGEENITYRHSNQEAFRVPIPRRRGATEDPSRKRHVVSGVMHKLKGSAGAFFFLIQTEDGDLFKATIDMVEDADGNPTGEVKRLKIKYFDTIPVSSSLCILKSGFLYAASQFGNHQFYQFEKLGDDDEELEFSSDDFPTDPKAGYDAVYFHPRPLENLALVESIDSMNPLLDCKVANLTGEDAPQIYTACGNGARSTFRMLKHGLEVNEIVASELPGIPSAVWTLKLNRGDQYDAYIVLSFTNGTLVLSIGETVEEVSDSGFLTSVPTLAAQLLGEDGLIQVHPKGIRHIRQGQVNEWAAPQHRSIVAATTNEHQVAVALSSGEIVYFEMDGDGSLAEYDEKKEMFGTVTCLSLGEVPEGRLRSSFLAVGCDDSTVRVLSLDPESTLESKSVQALTAPPSSLAIIAMDDSSSGGSTLYLHIGLHSGVYLRTVLDEVTGELTDTRQKFLGPKPVRLFQVTVQGRTCVIGLSSRPWLGYSDPITRGFLVTPLNYVDLEWVWNFSSEQCEEGVVGIQGQSLRIFAIENLGDTITQKSIPLSYTPRRLLKHPEYPMFYTIEADNNTLPPDLRAKLIAEPGVVNGDARILPPDEFGYPKGKGRWASCISVIDPLAEDQRVLQTIDLDNNEAAVSAAIVSFASQDSESFLIVGTGKDMVVNPRQFSEGYIHVYRFGEDGHELEFIHKTKVEEPPSALLGFQGRLLAGIGKTLRIYDLGLRQMLRKAQADVTPQLIVSLSTQGSRIIVGDVQHGITYVVYKPTTNKLIPFVDDTVSRWVTCTTMVDYESVAGGDKFGNMFLVRCSEKATQEADDESGGLHLINTRDYLHGTPHRLSLLAHSYTQDVPTSITKTSLVVGGQDVLLWSGINGTIGVFIPFVTREDVDFFQNLEQHMRTEDAPLAGRDHLMYRGYYVPVKGVIDGDLCERYTLLPSEKKQMIAGELDRSVREIERKISDIRTRSAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCF9</accession>
    <name>E3QCF9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">LysM domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_03691</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the secreted LysM effector family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092567.1">
        <property type="nucleotide sequence ID" value="XM_008094376.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCF9"/>
    <dbReference type="STRING" id="645133.E3QCF9"/>
    <dbReference type="GeneID" id="24409056"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03691"/>
    <dbReference type="eggNOG" id="ENOG502SNDA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010591_5_1_1"/>
    <dbReference type="OrthoDB" id="1193027at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052210">
        <property type="entry name" value="LysM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997">
        <property type="entry name" value="AM15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997:SF2">
        <property type="entry name" value="LYSM DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="355"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="237"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="416"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="522"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="262"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="522"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ28547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="699" mass="74870" checksum="F33FF252B86348F9" modified="2011-01-11" version="1">MALLPFALGKLGFQLYPLIPTQPMAEMLGVSENCVKALNTTLPCDDDLFRWTVKVDDVYWTEQDVSTLCVPDCQADARTWTETVASACSEDWLVVGDRAVPAETLSLRFVEGLEMACLRDTGSQWCLPASYNWTGSDVVQVDCAANPADPWCINPANVSAENSRISTLYDDDLLCSECFLNMMYRRVTSEFLPDTDHSDYLVSEFQDIQSVCQTSVGPLATRAVPLYPYASELQELNETAPEPTGTPSTGAPIVGDDGLPWDPEEDPDDPGIDEEIPDGEEDPDEAEPEPEPAEPVVPTNCTARAVDVRYASLDGIEACNELGEEYGVATGQLMYATGADDCYSYDFVCVPEACQLLRVNAGDTCETISKAISNDTDPVSVAQLMTWNPNLMGACDFLAESQYICISRPGGTWVKPPDADIPENSNGPVRGGPGSTETLPIVTDPSTVPDDRKQEGIPANCNRFVKADNTAASCWKIGNDAKITQTRLWELNPALGANGEHCGTQIWLDYYYCVGTAEDGTTTPTSTQSGPATTASATASSVPKPTPQHEGTDPTCNKWTQAGDGAGCWQLATDAGVDLALFYKWNPVLGADGENCGSMIWPTYYYCVGVSSAAVTPTTTVAPPATTTAPAKPTNTQAGIPANCSRFAQAGDGASCWQLASDNGIDLSVLFALNPVLGPAGENCGTQIWPDYYYCIATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCU9</accession>
    <name>E3QCU9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_03865</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092741.1">
        <property type="nucleotide sequence ID" value="XM_008094550.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCU9"/>
    <dbReference type="GeneID" id="24409230"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03865"/>
    <dbReference type="HOGENOM" id="CLU_2305878_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ28721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="100" mass="10747" checksum="00A49CCED83310D6" modified="2011-01-11" version="1">MKDATEPQVRSSNGIGDGASFVTPMAEGTRTATEDGRPRLKPNSDGIQLFFGGHAGREWGPMPCFTSQRRMTCVIPGALPEEVLRAAYFAYLPTAIGDQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDD6</accession>
    <name>E3QDD6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">RNA recognition domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_04052</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092928.1">
        <property type="nucleotide sequence ID" value="XM_008094737.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDD6"/>
    <dbReference type="STRING" id="645133.E3QDD6"/>
    <dbReference type="GeneID" id="24409417"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04052"/>
    <dbReference type="eggNOG" id="KOG0108">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109880_0_0_1"/>
    <dbReference type="OrthoDB" id="6730379at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051106">
        <property type="entry name" value="RNA-bind/splicing_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48028">
        <property type="entry name" value="GLYCINE-RICH RNA-BINDING PROTEIN RZ1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48028:SF4">
        <property type="entry name" value="SC35-LIKE SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="84"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="52"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="161"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="165"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="188"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ28908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="219" mass="24709" checksum="8FB56CF1F2BE86B2" modified="2011-01-11" version="1">MESLLPTERRLIPHPAYSFCFIYYKDAESVTTASENVNGTFWYGRRIVAKPQEPRDRTSEPQRRGERANRPPRVGRVHDGSPTTTLYVGNISFQSSDADLNNLFSTLDGVKDVRVAVDRATGWPRGFAHADFVSVEAATAALESLKGARILDRELKVQFAPPSLKETDRHDRMSQKSKSRGHNSQAEVEQRVEAEHEQAEEAQKEQKPEAGKQDMNWNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDX9</accession>
    <name>E3QDX9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Enoyl-CoA hydratase/isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_04211</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093087.1">
        <property type="nucleotide sequence ID" value="XM_008094896.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDX9"/>
    <dbReference type="STRING" id="645133.E3QDX9"/>
    <dbReference type="GeneID" id="24409576"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04211"/>
    <dbReference type="eggNOG" id="KOG1681">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_7_0_1"/>
    <dbReference type="OrthoDB" id="14970at2759"/>
    <dbReference type="UniPathway" id="UPA00659"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051750">
        <property type="term" value="F:delta(3,5)-delta(2,4)-dienoyl-CoA isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.12.10:FF:000004">
        <property type="entry name" value="Delta3,5-delta2,4-dienoyl-CoA isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000024">
        <property type="entry name" value="Delta3,5-delta2,4-dienoyl-CoA isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="entry name" value="Lyase 2-enoyl-coa Hydratase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045002">
        <property type="entry name" value="Ech1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43149:SF1">
        <property type="entry name" value="DELTA(3,5)-DELTA(2,4)-DIENOYL-COA ISOMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43149">
        <property type="entry name" value="ENOYL-COA HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0007">Acetylation</keyword>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="8 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ29067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="281" mass="30337" checksum="7725C4101D678420" modified="2011-01-11" version="1">MATFKDHAYTHFLVTSPAPFVVHVQINRPQKLNSFSEPVWREFGTIFGRLSHDPDVRAIVLSAVGDRAFSAGLDVQDASNSPLGSGLGGDPSRYATALRRHISEFQEAIAAAEKCEKPVICVLHGISIGIAIDISCCADVRICARNTRFAVKEIDIGIAADLGTLSRLPKLVGSTSWVKDVCLSARDFSADEALSVGFVSRVFESKDAAVEAGLKLAGFIAGKSPVAVQGTKELLNHARDHSVEENLRYTTIWNSAMLQSSDFKTALMSGLSKTKPTFEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3QE17</accession>
    <name>E3QE17_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">rRNA adenine N(6)-methyltransferase</fullName>
            <ecNumber evidence="9">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_04249</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>adenosine(1779)/adenosine(1780) in 18S rRNA + 4 S-adenosyl-L-methionine = N(6)-dimethyladenosine(1779)/N(6)-dimethyladenosine(1780) in 18S rRNA + 4 S-adenosyl-L-homocysteine + 4 H(+)</text>
            <dbReference type="Rhea" id="RHEA:42780"/>
            <dbReference type="Rhea" id="RHEA-COMP:10234"/>
            <dbReference type="Rhea" id="RHEA-COMP:10236"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74493"/>
            <dbReference type="EC" id="2.1.1.183"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="9"/>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093125.1">
        <property type="nucleotide sequence ID" value="XM_008094934.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QE17"/>
    <dbReference type="STRING" id="645133.E3QE17"/>
    <dbReference type="GeneID" id="24409614"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04249"/>
    <dbReference type="eggNOG" id="KOG0820">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041220_2_0_1"/>
    <dbReference type="OrthoDB" id="74991at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052909">
        <property type="term" value="F:18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000081">
        <property type="entry name" value="rRNA adenine N(6)-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020596">
        <property type="entry name" value="rRNA_Ade_Mease_Trfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020598">
        <property type="entry name" value="rRNA_Ade_methylase_Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011530">
        <property type="entry name" value="rRNA_adenine_dimethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00755">
        <property type="entry name" value="ksgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="DIMETHYLADENOSINE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727:SF7">
        <property type="entry name" value="DIMETHYLADENOSINE TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00650">
        <property type="entry name" value="rADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01131">
        <property type="entry name" value="RRNA_A_DIMETH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51689">
        <property type="entry name" value="SAM_RNA_A_N6_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 9" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 8 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 8 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribosomal RNA adenine methylase transferase N-terminal" evidence="11">
        <location>
            <begin position="46"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ29105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="378" mass="42066" checksum="B4E6460EE720C330" modified="2011-01-11" version="1">MGKAKAPKRNAASSSSGPYSRPSQKTNNVFKFNTNVGQHILKNPGVADAIVHKAELKPTDTVLEIGPGTGNLTVRILEKSKKLIAIEFDPRMAAEVTKRVQGTPEQRKLEVMLGDAIKVDWVPFDVLISNTPYQISSPLVFKMLAMPKPPRQAILMFQLEFGQRLVAKPGDKLYGRLSVNANFWATCSNVMKVSKANFRPPPQVDSCVVRIVPKQGAERPTIAFEEFDGLLRICFNRKNRTMRASWLGTKEVLQMLEKNYRTWAAMNNVPLDDTLVEDDEDEAMEMDDDADAGADDDDVEPMVDDTPEFFKELGAAASKAPEKTKSKRKKTKVAALVRSKIERALESTGLLEKRARLCDETDFLKLLSALNSEGIHFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>E3QE34</accession>
    <name>E3QE34_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">cysteine desulfurase</fullName>
            <ecNumber evidence="3">2.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_04266</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron-sulfur (Fe-S) clusters. Plays a role in both tRNA-processing and mitochondrial metabolism. Involved in the 2-thio-modification of both 5-carboxymethylaminomethyl-2-thiouridine in mitochondrial tRNAs and 5-methoxycarbonylmethyl-2-thiouridine (mcm5s2U) in cytoplasmic tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(sulfur carrier)-H + L-cysteine = (sulfur carrier)-SH + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:43892"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="EC" id="2.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="3"/>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093142.1">
        <property type="nucleotide sequence ID" value="XM_008094951.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QE34"/>
    <dbReference type="STRING" id="645133.E3QE34"/>
    <dbReference type="GeneID" id="24409631"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04266"/>
    <dbReference type="eggNOG" id="KOG1549">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003433_0_2_1"/>
    <dbReference type="OrthoDB" id="10250117at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990221">
        <property type="term" value="C:L-cysteine desulfurase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044571">
        <property type="term" value="P:[2Fe-2S] cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070903">
        <property type="term" value="P:mitochondrial tRNA thio-modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002143">
        <property type="term" value="P:tRNA wobble position uridine thiolation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000003">
        <property type="entry name" value="Cysteine desulfurase IscS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000002">
        <property type="entry name" value="Cysteine desulfurase IscS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00331">
        <property type="entry name" value="Cys_desulf_IscS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010240">
        <property type="entry name" value="Cys_deSase_IscS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02006">
        <property type="entry name" value="IscS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002806">
        <property type="entry name" value="PRK02948.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010611">
        <property type="entry name" value="PRK14012.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11601:SF34">
        <property type="entry name" value="CYSTEINE DESULFURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11601">
        <property type="entry name" value="CYSTEINE DESULFURYLASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="12">
        <location>
            <begin position="108"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00045623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00050776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ29122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="507" mass="55845" checksum="2DA828D4CC392DA9" modified="2011-01-11" version="1">MASITSTAFRQAGRLCRHTTAPGISSRGISSLSRVATAPAQRLSQQRRYVSETRRDNAQVNVETAIKLDTKDFIDVVPQSPDAPNVLVSPMAEVLKQVTTMEEGQRPIYLDMQATTPVDPRVLDAMLPFYTGIYGNPHSRTHAYGWESEEAVETARQHIAKLIGADSKEIIFTSGATESNNMSIKGVARFFGRSGKKKHIVTSQTEHKCVLDSCRHLQDEGFEVTYLPVKNSGLIDMDELAAAIRPDTALVSIMSVNNEIGVIQPLEQIGRLCREKKTFFHTDAAQAVGKIPMDVNAMNIDLMSISSHKIYGPKGIGACYVRRRPRVRLDPIISGGGQERGLRSGTLAPPLVAGFGEACRIAYEEMEYDSKRIKALSDRLLNGLLSLEHTTQNGDPKHFYPGCVNVSFAYVEGESLLMALKDIALSSGSACTSASLEPSYVLRALGNSDESAHSSIRFGIGRFTTEQEIDYVLKAVKERVDFLRELSPLWELVQEGVDLNTIQWSQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>E3QED8</accession>
    <name>E3QED8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">DNA-directed RNA polymerase subunit beta</fullName>
            <ecNumber evidence="13">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">GLRG_04388</name>
    </gene>
    <organism evidence="21">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:21249"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="13"/>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093264.1">
        <property type="nucleotide sequence ID" value="XM_008095073.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QED8"/>
    <dbReference type="STRING" id="645133.E3QED8"/>
    <dbReference type="GeneID" id="24409753"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04388"/>
    <dbReference type="eggNOG" id="KOG0216">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000524_5_1_1"/>
    <dbReference type="OrthoDB" id="10248617at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006363">
        <property type="term" value="P:termination of RNA polymerase I transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006362">
        <property type="term" value="P:transcription elongation by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006361">
        <property type="term" value="P:transcription initiation at RNA polymerase I promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.270.10:FF:000011">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.150:FF:000004">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1070.20:FF:000003">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1100.10:FF:000008">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1100.10:FF:000016">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1110.10:FF:000007">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1070.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="entry name" value="DNA-directed RNA polymerase, subunit 2, domain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1800.10">
        <property type="entry name" value="RNA polymerase alpha subunit dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1110.10">
        <property type="entry name" value="RNA polymerase Rpb2, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037034">
        <property type="entry name" value="RNA_pol_Rpb2_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009674">
        <property type="entry name" value="Rpa2_dom_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06883">
        <property type="entry name" value="RNA_pol_Rpa2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 13" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RNA polymerase beta subunit protrusion" evidence="17">
        <location>
            <begin position="39"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="16">
        <location>
            <begin position="200"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="18">
        <location>
            <begin position="488"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase I subunit RPA2" evidence="19">
        <location>
            <begin position="593"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase subunit 2 hybrid-binding" evidence="14">
        <location>
            <begin position="700"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="15">
        <location>
            <begin position="1078"/>
            <end position="1142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU363031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF04563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF06883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EFQ29244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1225" mass="136801" checksum="7022095A6BDB4777" modified="2011-01-11" version="1">MAPSATSTEWDHQYNTLRRENLFRNPPKDHTAYPALQEAVSPHIDSFNALFRTDGKSLLARGLEDIGTKTYLDGDDRAGLEGKNRLSIRIKSVALQKSQLPPSNKFARNREVLPAECRERHCTYRGRLSATFEYRINDGDPKEFVRELGQVPIMVKSNRCHLEGNSPAQLVQRKEESEELGGYFIVNGIEKIIRMLQVNRRNFPMAINRPSFQNRGQGYTPYGIILRSVRPDETSQTNVLHYLSDGNMTFRFSWRKNEYLVPVMMILKSLVETNDREIFEGLIGLSGSKSSKNTFLTDRVELLLRTYKSYCLYSKTETRAYLGEKFRVVLGVPDTMSNYDVGTEFLRKIVLVHLGNINVTEKEDNDKFRMLLFMIRKLYALVAGDCSVDNPDAVQNQEVLLGGFLYGMILKERLEEFLTTAVRLSLREWTRKHPATPFTSQDFAKEFPANIFRHANENLGNGLEYFLSTGNLTSPSGLDLQQTAGFTVVAEKLNFLRFLSHFRMIHRGAFFAELKTTTVRKLLPESWGFMCPVHTPDGAPCGLLNHLAHKCKIMTEAVDASKIPGLVAELGAVETSSAATDESVVIMLDGRIVGFCTPRESLRIADTLRYWKVEGTHGVPLQLEVGYVPPSNGGSYPGIYLASAPARMVRPVKYLPLDKEDFVGPHEQPYMSIAVVEDEIVSGESTHVEFTPTNMLSILANMTPFSDFNQSPRNMYQCQMGKQTMGTPATALRYRTDNKMYRLQSGQTPVVRSPLHNAYGFDNFPNGFNAVVAVISYTGYDMDDAMILNKSAHERGFGHGTIYKTKKITLKDESRTRSVKNISKLFGFAPGGFVKGHYRGQLDEDGLPYVGRLVQEGDVLCAWHTVSADYSGKLVNLDGQTHYEKYKDSETAFVEEVRVIGSETGNEPAQTISIKLRVPRSPVIGDKFSSRHGQKGVASQKWPAVDMPFSESGMQPDVIINPHAFPSRMTIGMFVESLAGKAGALHGLAQDSTPFKFNEENTAADYFGHQLMKAGYNYHGNEPMYSGITGEELAADIYVGVVYYQRLRHMVNDKYQVRTTGPVVPTTGQPIKGRKRGGGIRVGEMERDALLAHGTAFLLQDRLLNCSDYTRSWICRSCGSFLSVQPTVSPFVGKKKQVTTVRCRNCAVPIDAGDAESAAKVEGEIWEDGQGNQWVGGENTTVVVVPGALKFLDVELAAMGVKLKYRVDSRDAPRKGPLKPMSSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEG1</accession>
    <name>E3QEG1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04411</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093287.1">
        <property type="nucleotide sequence ID" value="XM_008095096.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEG1"/>
    <dbReference type="STRING" id="645133.E3QEG1"/>
    <dbReference type="GeneID" id="24409776"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04411"/>
    <dbReference type="eggNOG" id="ENOG502S5SN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018682_0_0_1"/>
    <dbReference type="OrthoDB" id="3474066at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052973">
        <property type="entry name" value="Fungal_sec-metab_reg_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35392:SF3">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35392">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="707" mass="79671" checksum="297690BCC5C1C240" modified="2011-01-11" version="1">MSPHYQDGSLSPEFEDKSRPVGHHSHHVFDGIGPQQLPPGFQGPGLNGWTEGLQTMALVMCRSCWNPCGVSNGVYEPLSGTEANGYNYGTSLNRPYEVEKPPSAQISQPEVYVPPAIAPSVSNPFPVADTGMVSTYAPQYQTLQESPSHTMAPRNSGHDSVVYPVDVSTSVYYPDASVIPGGDPINFPNLGNTDRHIPTREGMPGPYDDNMMGMAVTCAVSPTSSIPARATSFALAPTYAMPCVKTEDADMSARSNSLDVVFPHQRPPASKRGPFKDQKAREETAVTRKNGSCIRCKMQRVRCKTDPDDPKGPCVGCKPKTTNNHHKQLFRQPCVRRKITECNFFKRGQAPGYEWTRRWGNGIVDNINNWASNEVKTVRLWEGYTPVDMCVQLHVRKFIPQPGDKLERTWVAKGVKKSVAIPAYAITNLDEAQAAYEDYIKRGVVGCFKSVIESVMSVQMGVRDQLIYNTYLKAWELSQSVSTPPDERDLLVQTLELWMAVRLTTKSVQIVGEETLGMSRDILDSSSPQHGCIPLPPVMGAQLDLVLIQHIQARLRREMLEKLQKMTLQNKQKTWLTTYLVTFMLLHNIALVTEHDASYAQKHGMGKKFARELDVQEYHLGGTILLAYFHYCNKGIYPFSEECRDQDLRTLAQLDEDAVQFIHWTRSQAMAHKHEWEEVQQANQYEQPYFFVSQLFQRDWQPQMWAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEH9</accession>
    <name>E3QEH9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Amino acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_04429</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093305.1">
        <property type="nucleotide sequence ID" value="XM_008095114.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEH9"/>
    <dbReference type="STRING" id="645133.E3QEH9"/>
    <dbReference type="GeneID" id="24409794"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04429"/>
    <dbReference type="eggNOG" id="KOG1286">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007946_12_0_1"/>
    <dbReference type="OrthoDB" id="3900342at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000017">
        <property type="entry name" value="Amino acid permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004840">
        <property type="entry name" value="Amino_acid_permease_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004762">
        <property type="entry name" value="Amino_acid_permease_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00913">
        <property type="entry name" value="2A0310"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF1">
        <property type="entry name" value="GENERAL AMINO-ACID PERMEASE GAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
        <property type="entry name" value="AMINO_ACID_PERMEASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="115"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="195"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="250"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="337"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="395"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="438"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="467"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="509"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="551"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="10">
        <location>
            <begin position="114"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="57"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ29285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="617" mass="67992" checksum="67B2E4627125FD8E" modified="2011-01-11" version="1">MAPYNEDVELSAIKVKEDSLTLGSSYSMRREPVYDPTPAPGVFARVFESFKRDPGQMTENMRHHRRHRRSNSNSSIDLEPGNERVLNGVHYYDIRLANLQTSNTLLSRKLKGRHLQMIAIGGSIGTGLFVASGQALEIGGPASLLMAFSLVGAMLFCTCQALGELAVAFPVAGSFSAYSTRFLDPSWGFAMGWNYALQWLTVLPLEIIAASITITFWDPNITKAIFVTIFLIGIIAINLFGVKGYGEAEFIFSIIKIIAVIGFILLGIVLNCGGTPDSGYIGGRYWQDPGAFHNGFKGLCSVFVTAAFAFAGTEMVGLAAAETANPRKSLPTAIKQVFWRITLFYVVALTLIGLLVPYNEARLLGADSSVDATTSPFVIAIENARIDVLPSVMNAVILIAVLSVGNSAVFGSSRTLAALADQHQAPRFLSYVDRKGRPLMAIGLAGGFGLIAYLADLEQQDEVLDWLLAISGLSSVFTWASICLCHIRFRRAWALKGHGLHELAFRSQVGVVGSWCGLIMNLLVLVAQFWVGAFPVGWEKWEPEAVARNFFLRYAAFPIVVIMYVVHKFYFRTTIVRVKDMDVSTGRRDFNLGILVTQEQEERQSWPTWKRVYKFLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEP3</accession>
    <name>E3QEP3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_04493</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093369.1">
        <property type="nucleotide sequence ID" value="XM_008095178.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEP3"/>
    <dbReference type="GeneID" id="24409858"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04493"/>
    <dbReference type="HOGENOM" id="CLU_2885645_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ29349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="63" mass="6791" checksum="CA8C68B6808C1134" modified="2011-01-11" version="1">MCQELAGQKAWISYTGVLIFMIPFSGREALSATPSMARVTLWAGILDMEGTSLLGRTEKAGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEV1</accession>
    <name>E3QEV1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyldiphosphate specific]</fullName>
            <ecNumber evidence="5">2.5.1.87</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_04551</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>n isopentenyl diphosphate + (2E,6E)-farnesyl diphosphate = a di-trans,poly-cis-polyprenyl diphosphate + n diphosphate</text>
            <dbReference type="Rhea" id="RHEA:53008"/>
            <dbReference type="Rhea" id="RHEA-COMP:19494"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:128769"/>
            <dbReference type="ChEBI" id="CHEBI:136960"/>
            <dbReference type="ChEBI" id="CHEBI:175763"/>
            <dbReference type="EC" id="2.5.1.87"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the UPP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.87" evidence="5"/>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093427.1">
        <property type="nucleotide sequence ID" value="XM_008095236.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEV1"/>
    <dbReference type="STRING" id="645133.E3QEV1"/>
    <dbReference type="GeneID" id="24409916"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04551"/>
    <dbReference type="eggNOG" id="KOG2818">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051870_1_0_1"/>
    <dbReference type="OrthoDB" id="19639at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904423">
        <property type="term" value="C:dehydrodolichyl diphosphate synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045547">
        <property type="term" value="F:ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1180.10">
        <property type="entry name" value="Decaprenyl diphosphate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038887">
        <property type="entry name" value="Nus1/NgBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036424">
        <property type="entry name" value="UPP_synth-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21528">
        <property type="entry name" value="DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT NUS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21528:SF0">
        <property type="entry name" value="DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT NUS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64005">
        <property type="entry name" value="Undecaprenyl diphosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ29407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="328" mass="37789" checksum="280D30C9CEEC4558" modified="2011-01-11" version="1">MPSKRDRRVLRTDDVANLEDEEKRRLLQEYLPDGPPEGAQRQWRDDNIPSKGRFGLRRALRTKLHLTVYTILHAFFSLYIRIRQAWHLVCYHVSSILFYHHRTPEYIERDVVGLKQKPKHLSVILKREEGGRHGAELERLVAEAAEIAVWCVCAKIPVLTVYERTGLLKHYLPHLQQSIIQKSRSYFGRHQPSLTVAMPHSDDVLESPAHGDFVRDDPRHLKVLFISAEDGRDSMVDLTRTLTEMSQKGKLHPGDISTDLIDAELSEGIMPEPDLLISFGPYVDLDGYPPWPIRLTEIFCLPDNQGVGYQVFLRALNNFAKAQFRKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFG9</accession>
    <name>E3QFG9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="10">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_04751</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>feruloyl-polysaccharide + H2O = ferulate + polysaccharide.</text>
            <dbReference type="EC" id="3.1.1.73"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the tannase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="10"/>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093627.1">
        <property type="nucleotide sequence ID" value="XM_008095436.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFG9"/>
    <dbReference type="GeneID" id="24410116"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04751"/>
    <dbReference type="eggNOG" id="ENOG502QPXZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014819_1_0_1"/>
    <dbReference type="OrthoDB" id="3039123at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030600">
        <property type="term" value="F:feruloyl esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011118">
        <property type="entry name" value="Tannase/feruloyl_esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938">
        <property type="entry name" value="FERULOYL ESTERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938:SF15">
        <property type="entry name" value="FERULOYL ESTERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07519">
        <property type="entry name" value="Tannase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0858">Xylan degradation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ29607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="412" mass="45165" checksum="86EE51F50A88A4E8" modified="2011-01-11" version="1">MRISRPLVQVPLAVGFAHGSTIADCESLAGPAEPPKQDDTRDDLNYGASQQFATIGTNNGHDGISGSPFYKNPGVLEDYVYRAVHLEAQLGKAVAAEFYGKNHTKAYYIGCSTGGRQGFKEAQSFPEDFDGIVAGAPAFDLVSLQSWTGQLFLKTGTSKDSRFLTPAKWGLVYNDILRQCDGLDGLEDGIIEDPNLCQYRPEGLICSGGSSGAACLTSEQVEMPNAYPMDWWRYAVYNDPKWNISTLNHHDYEVAAQQDPWNVSTWQGDLSGVRQRGVKILHYHGLQDPAISSDNSERYCDHVSRTMNLPSAELDGFYRYFRISGMRHCGGGTGASLIGGSTNGFASFEPDTNVLSAVVRWVEEGVAPVYILGSRKTASGQIDLQRKHCKYPARNVYKDQGDPSTPDSWECV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFP3</accession>
    <name>E3QFP3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">beta-glucosidase</fullName>
            <ecNumber evidence="10">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_04872</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="10"/>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093748.1">
        <property type="nucleotide sequence ID" value="XM_008095557.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFP3"/>
    <dbReference type="STRING" id="645133.E3QFP3"/>
    <dbReference type="GeneID" id="24410237"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04872"/>
    <dbReference type="eggNOG" id="ENOG502QR4D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004542_2_0_1"/>
    <dbReference type="OrthoDB" id="416222at2759"/>
    <dbReference type="UniPathway" id="UPA00696"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.300:FF:000002">
        <property type="entry name" value="Probable beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1700:FF:000003">
        <property type="entry name" value="Probable beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF2">
        <property type="entry name" value="BETA-GLUCOSIDASE F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 10 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178435" description="beta-glucosidase" evidence="11">
        <location>
            <begin position="25"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type III-like" evidence="12">
        <location>
            <begin position="774"/>
            <end position="847"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ29728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="869" mass="93243" checksum="D7C2DEDE94697D64" modified="2011-01-11" version="1">MASTFSVKSLAIGLLASQVSLCDGAVINPRDAVPAGYVAAPYYPAPYGGWVSDWSDSYRKAKLILMFDFTNTHVGRCVGNSGSIPRLGIPSLCLADSATGVRLADNVTVFPAGITTGATFSKDLMYARAVAMGKEFRGKGANVFLGPMVGPMGRKPRGGRNWEGFGTDPALNGHAAYLTVKGVQEQGVIATVKHLIGNEQEIARMYTPLWEGYSANIDDRTLHELYLYPFAMALRAGPGSVMTAYNAVNGSACSQNSYLINGILKDELGFQGFVMSDWLSHMSGVGSALAGLDFDAPGDQQIPLTGYSYWAYDLTRAVLNGSVPVDRINDMATRVLAAWYQMGQDESFPPTNFDTNSNSRVADLYPAAWPFSPSGVVNEFVQVQADHYLVARQVAQEAVTLLKNNGSLLPITTSTPIKIFGTGAQTNPDGPNACADRSCNKGTLGIGWGSGTVNYEYMDDPLSAFKNRSSNVVYYNTDSFPSVPAPTADDVAFVFISSDSGENSYTVEGNAGDRSSTGLNAYYNGDQLVKDAAAKYQNVVVVIHTVGPVLVDEWIDLPSVKSVLVAHLPGQEAGESLASIIFGEASPSGHLPYSMTKQESDLPDSVTKLLSVQLFGQPQDTYTEKLYIDYRYLNKNGIKPRFAFGHGLSYTTFSYSNATISSVTPLTATPPARPVKEGILDYDGPIPAWTEGVAPSGFNKIFRYIYSWCTESEAKDAVAASTTKTYPYPEGYSTTQKPGPPAGGGEGGNPALFDVAFTVSVQVTNMGAQYSGKASAQAYVQFPDGGPDTPVIQLRDFEKTANLAPGESTTVTLELTRRDLSIWDVVSQNWIVPNPTGRYKIWVGEASDKLFLACYTDSGNCEEGLPSPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QG83</accession>
    <name>E3QG83_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Oxidase ustYa</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_04823</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Mycotoxin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ustYa family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093699.1">
        <property type="nucleotide sequence ID" value="XM_008095508.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QG83"/>
    <dbReference type="STRING" id="645133.E3QG83"/>
    <dbReference type="GeneID" id="24410188"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04823"/>
    <dbReference type="eggNOG" id="ENOG502SMKF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042941_4_0_1"/>
    <dbReference type="OrthoDB" id="3687641at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043386">
        <property type="term" value="P:mycotoxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365:SF11">
        <property type="entry name" value="TAT PATHWAY SIGNAL SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365">
        <property type="entry name" value="YALI0B05434P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ29679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="268" mass="30545" checksum="28DE35EC6282DC11" modified="2011-01-11" version="1">MSEAKYANIGLDDHDRDDRSSTEVEESLIGDGKACRSCLANEYQSPAARRTNRWLSMLKSSRYFVDTILLLVILGLLVRQQTQVPALSTLHPGDDLTGVSGKFSTQIKTFTPDYEGKYAPNDTSKFFTDEVLNNWNELMPYGMGFQWVNDTHKYHDLPTPIVWPEKTVFTTSMTHQLHCLFAVVQTYSGLSSGHEIPDDHHWHMIHCFAYLRQTIMCSADMALEGLETTFPDHNGGSDGWDSKHVCKDYSQVKNYLEGVRAYDDREIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGG2</accession>
    <name>E3QGG2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">LisH protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_05094</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ29950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093970.1">
        <property type="nucleotide sequence ID" value="XM_008095779.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGG2"/>
    <dbReference type="STRING" id="645133.E3QGG2"/>
    <dbReference type="GeneID" id="24410459"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05094"/>
    <dbReference type="eggNOG" id="KOG0273">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018409_0_0_1"/>
    <dbReference type="OrthoDB" id="1367865at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034967">
        <property type="term" value="C:Set3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.960.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045183">
        <property type="entry name" value="Ebi-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22846:SF2">
        <property type="entry name" value="F-BOX-LIKE_WD REPEAT-CONTAINING PROTEIN EBI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22846">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08513">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00667">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="100"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="217"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="107"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="227"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ29950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="653" mass="70927" checksum="C77427A3AE5C3002" modified="2011-01-11" version="1">MVTKEYLDSDRVNFLVWRYLLEGNYRETAAKFQKEWHIQQPHRHFEFANHVKSHALVSIINKGLCYHALEREHAKKSVPPDAAAAAEALQVGLFGPLIAQPPHKVEEDEDADGEVDDTEMEVENTRKRQFDSRPQQHMVNGGSPSKRPRLSNGYESTNGADAATDPMELDSHGDNNHAYPSPLEGEQAPTPTPRTDGPEQGTQVDKVEELATETTFLRLMPDDSNSTTTTTTNVQDGSDSTTATATASAGAGGPGTSPSPANGENAPILLRCEWNPKDPSILAAAGTDALARIWTISRSSTMTPAPAPEPDGHVHGVHRPFHSLIDDETPKTATVGQLAWNWGGTAIAIATEHGDKASVHIWAKDGSHIDKFDVSDPPVIKLRWSPSDAALLAIAPDNSSVNGNAGALVTVYHSLTSNTLSYFLPNHDLLNWPLDAAWTSETEFLLTGGDVMLSLQCTETSIVPNKKLESREDDTFTQVVYDWRSKLAATASDKGILDLWDENGQRLSITAHSGAITAVQWQPLPEDSNIPEDERLIATGGDDCAIIISNAKDPEPGKAKSILTMESPIVSIAFTPDGAFIAGATAGRILIWKVGEHTMPRASWSRAPHPGWLSPKASSEPEEEDEHCLCWDADGQRLAYGANSRLAVINFRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3QH25</accession>
    <name>E3QH25_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Aspartic proteinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_05331</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697348">
        <property type="protein sequence ID" value="EFQ30187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094207.1">
        <property type="nucleotide sequence ID" value="XM_008096016.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QH25"/>
    <dbReference type="STRING" id="645133.E3QH25"/>
    <dbReference type="GeneID" id="24410696"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05331"/>
    <dbReference type="eggNOG" id="KOG1339">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013253_7_1_1"/>
    <dbReference type="OrthoDB" id="771136at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47965:SF12">
        <property type="entry name" value="ASPARTIC PROTEINASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47965">
        <property type="entry name" value="ASPARTYL PROTEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005673313" evidence="9">
        <location>
            <begin position="19"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="526"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="10">
        <location>
            <begin position="63"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="559"/>
            <end position="622"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ30187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="622" mass="66897" checksum="27E21936064C53D7" modified="2011-01-11" version="1">MKASFLLVAAACAAVAEAEVHLPYALQSPLIAAAAADSGVKSRTPDDRRSMPTLDILTDGWNYLVNVSVGTPPQQMSMRLNVQASASWVPNVESCDSSSRRYINASSYYEEYIRCTEKINKLIGGEYVVGDWISDVLDLAGTRIPKFVMGGVEIQMADTMVGVLGLGYNESYYHSDVEQSDSTTTLTVPERLVKDGLITSPAYSLWLDDKSAKSGKLLLGAIDRSKFEGPLIRIRTNSFSASSASGRTKTFDTVIHSVNGTESATDDLKPLGNGSLSSSERYYLYENRFLPVKLAPESTLSVLPPALAQDSWFLAGAFWNADLLRTVIPCTVAEKSTGHIVMQLDGTDGPVLNVSIADLGTHNSLTGYSIEDYVLGGAVSKQAYIVFNLANAEMAIAQTKSKHEKTQTRYMVAVRGNPPPTTRPRRLPREYRSTDLRLTRHVELIGTTLGLKISVARYRAARGHGITATEDIVPYCFFSINAKYSPECTGDGSGAGNSGKDGNGDGGYGGYGDICLPSSISRSIKLGVGLGVGLLCLVVICLSIWAIRRCRRIRKAEEHLSEKQADMEQGAADARIGAGGGDNVAQDVSLPQKPPSAVTREPPTTDAAEGRDNLEDAVSTRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHR9</accession>
    <name>E3QHR9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05551</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697349">
        <property type="protein sequence ID" value="EFQ30407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094427.1">
        <property type="nucleotide sequence ID" value="XM_008096236.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHR9"/>
    <dbReference type="GeneID" id="24410916"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05551"/>
    <dbReference type="HOGENOM" id="CLU_1272192_0_0_1"/>
    <dbReference type="OrthoDB" id="10606926at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="217" mass="23850" checksum="05FCF4CDE682E9D9" modified="2011-01-11" version="1">MKMKLFGSSPTIDGRDILRTLGSLGGEIFSQKGGHESSPRLGYSDFLSLNGPHERRESESESDIIGKSSKGSSIYPLVLEDLEIPTDAAFTFRVCEGAFIYEGRYYKHLSHKSDTHIHASEQQQDDLSTRDVAPITRSALTQPLSLTAALREGCGEVLISFDVKVSGYFFSVNAFEAILNFLCLDVSRDCAHDVDSPLPTDVEKQIVIRKVGNDGCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHS0</accession>
    <name>E3QHS0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05552</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697349">
        <property type="protein sequence ID" value="EFQ30408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094428.1">
        <property type="nucleotide sequence ID" value="XM_008096237.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHS0"/>
    <dbReference type="GeneID" id="24410917"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05552"/>
    <dbReference type="eggNOG" id="ENOG502SPAQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1124442_0_0_1"/>
    <dbReference type="OrthoDB" id="5421021at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="247" mass="26288" checksum="C645E5320F5421F8" modified="2011-01-11" version="1">MAVQLQSDVGTLAFAGLGAFSTVLSAMSADDVHPIAMIQLENLGLLFHVNGTNAGLIPEVLKNAMSHSIGRLSLSVGWRRGDAVSMLGDSAGGQAISLLMTALDGIYNRQEYGLILSKLCTSLLPKSMPASNPVHLADVANLVAAKAGRLSIGNLLAQQTHRVLSVYDHLGKKSPGDLLEIPTTESIVQLLECLSNLQQDRHIVRVSGSIGIIYLGALILFMFPQSAMIVVESVVIHDNEGRRLELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QI12</accession>
    <name>E3QI12_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ran-interacting Mog1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_05644</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MOG1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697349">
        <property type="protein sequence ID" value="EFQ30500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094520.1">
        <property type="nucleotide sequence ID" value="XM_008096329.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QI12"/>
    <dbReference type="STRING" id="645133.E3QI12"/>
    <dbReference type="GeneID" id="24411009"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05644"/>
    <dbReference type="eggNOG" id="KOG3329">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081345_1_2_1"/>
    <dbReference type="OrthoDB" id="10255285at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1000.10">
        <property type="entry name" value="Mog1/PsbP, alpha/beta/alpha sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007681">
        <property type="entry name" value="Mog1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016123">
        <property type="entry name" value="Mog1/PsbP_a/b/a-sand"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15837">
        <property type="entry name" value="RAN GUANINE NUCLEOTIDE RELEASE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15837:SF0">
        <property type="entry name" value="RAN GUANINE NUCLEOTIDE RELEASE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04603">
        <property type="entry name" value="Mog1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55724">
        <property type="entry name" value="Mog1p/PsbP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ30500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="198" mass="21909" checksum="D55E93A8393B4957" modified="2011-01-11" version="1">MTRYKGTPLYGGALVADLPEKFADVSKLREVPDNQEVWIDSDGFTSIIFDITERVGPAGSSPEIDGRAMTTHLEELVGEDIDTVKVWNTTETSFSRLSPDFPAYTLIATQTPHTKPGSKSGSSAPDFTAIILTLLRLEKESTDILVTINVPHIKGEYDEADVDLELGKQGKLIGDAVEYAARIWETFKVKDWTLFQEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QI34</accession>
    <name>E3QI34_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phenol acid carboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05666</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
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                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
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                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
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            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05666"/>
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        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
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            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
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        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
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            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
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                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
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            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
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    </evidence>
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        </source>
    </evidence>
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        <source>
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    <sequence length="461" mass="50890" checksum="61E1655B951DC443" modified="2011-01-11" version="1">MCNILRPVAECQQCLKTVELEPLPQLCSQIANTDSSEIGLCGTLTSQTVPNPRDRVCEDCHNSAQLEAERRNDSNSEAKSYPPADHLESSLPPSEMTAHNTVAQHGSLATTSSDAERRMRERRAKYSCPSETSSEGAEDDRVPVDTPAALSRSKAQPPLLETVLVAGTPHVHTPTPRSATTLRIEAPWDEPAPEQASDDPWWYPEIWGPARDLPRELAEFLRRIPPADTFHNHRIYVFHNGEDKVEQATVLLATPEGSRARVVSGALYDEGARLVTRRQLARARYEQLSSEEREKMAKGEQCCIFYPCRVASCPLLHDEEQHQPIKPVGETLLGAMERGYVWRKNWGATRVPGPTPPVSSRRRYGGSRSPPRQPIRGTAAAAQQTSARAEDRGFSGTPSGLSSTACSPARSGSTDRFADRGRVGRIRPAHHRSVVRRDGSPVPSGERTRRERAPCPKPEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QI42</accession>
    <name>E3QI42_COLGM</name>
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        <submittedName>
            <fullName evidence="2">Histone deacetylation protein Rxt3</fullName>
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    </protein>
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        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
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                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
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                <person name="Panaccione D.G."/>
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                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
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                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
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            <dbReference type="DOI" id="10.1038/ng.2372"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
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    </dbReference>
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        <location>
            <begin position="330"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="409"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="430"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="496"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="576"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="669"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="696"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="716"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="746"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="964"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1121"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1150"/>
            <end position="1159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1166"/>
            <end position="1179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1187" mass="130942" checksum="D872C1CCC496F649" modified="2011-01-11" version="1">MDPRQQPPQLPFSRNAASQYSRSPFPPSSTTTANSTPNQSPFPPVSHPHAEHQRRSSENPYYSSGPRPYSQEPNNAGPPPSSGHSRHPSASSLPPGAPLNRNMPPPGSPPQPGNPPPPSHQMGHYGLPAPRAPPLSVGHPSSFPGGRELPSLNSIQRTGSTGSSMSISSMLGGPPPARDSQPPPSHYHPPATSASSGPTFAPTMQASPRMHSASSEYQPFRRQQTPEHARPYDPRGSAAASPQGAYSTTPEVQRYGTPQQGYHQRGPSTQDGRESNRMSQGPPPPRPTSQPKSFQQQNMPQRTVDMGRNNGPEEMYQRREEVPRGSMEYNPERPDLKPMTFDDRYRAERERREEIEFRERERRERAYSGGDGGRAPQGDYRPQEVQRGQPPPFTRPPEQREQGPWPPRQQQQQQHHQQQQQQQQQQQQHQHQHQHQHQHQHQHQHQQQPPPPFDQSRVPYDPAGLHPRHHHEYPPSSAPNYPGQSHPAPAPQFQQQPPPNDRYPPGPPNHPQQPPPGQPGQHQQQQPFDSPERQRANHLHPQTQPAPTHRRPGEEGPPPPSVAYNTPHVPPMYDSPRNRPMEDHPNNNHHHQRNLLAVQEINRKGRVSPMPQAVQGAQPQLPGPAGEPGIKSEFGRMFSGIGSGVTGLGVGSPVTAGAQLPYTNASLARRDETDSATHESGPEAVAPKPKGRRRKLKEEDTKGDDESTGRLTPVGRAKRPKTHAHHHHQYVPVPSGLSTTTNDSSHHHHHHHHHGADHANAPTPAPVGITPFKNVKGITPIPSPTTGPTKDLPAAHHHHVPRPAHLHTHVKEAPAKQAAQSPTSILPPKPKTIVTSKAVLEAVAHRPRTHLGDVLYEPKLKPARQIPNVPSGRGFSSTPTPLPWDMIKDKENCTLTVKVPKVHLTPVAREEITARRALWGTDVYTDDSDVVAACIHGGWIRGEWGDDVDTSLLDLDRGLSAPEKEFPASKRRNKEKEKDEKARLEANSATYLDQPPKTGPVHVPADRDMHVSIVILPRLEKYSSTTRFGLQSREYGGRYNGRQSIHDGLSFMVTGIRWVTNGAGAQSRLRGKGRRERMRKAMGEINVASRGLNGAALEREKQRLDKIRGEIVSGTWWKKEKGRENGVADKEHSSTTEGEKENRSGDEARNTTSPATNGATAMKGASADKADKMDVDETGKAAAATKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIG9</accession>
    <name>E3QIG9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DUF202 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_05723</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094599.1">
        <property type="nucleotide sequence ID" value="XM_008096408.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIG9"/>
    <dbReference type="GeneID" id="24411088"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05723"/>
    <dbReference type="eggNOG" id="ENOG502S23D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120561_0_0_1"/>
    <dbReference type="OrthoDB" id="5525680at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003807">
        <property type="entry name" value="DUF202"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052053">
        <property type="entry name" value="IM_YidH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34187:SF3">
        <property type="entry name" value="DUF DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G11150)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34187">
        <property type="entry name" value="FGR18P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02656">
        <property type="entry name" value="DUF202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="79"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="152"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="DUF202" evidence="6">
        <location>
            <begin position="64"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ30579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="195" mass="21222" checksum="8A37862181A6E2BD" modified="2011-01-11" version="1">MASRPDIDDEDLTFHCCAPLRASELLKPVEVGDIGGPGHAGKPMFLAWPIFGPLLFQNETSDARDHCANERTFLSYLRLSVYMSIVAVAIVLSFHLKSEPSPLELRMAKPLGIIFWVLSVACLCLGLGNYTKTVNKYSRKTAIVQTGWRTQLVLSIVALSIVGTCVVLLVIARITSRTQGAHPSDDAAYAAGHIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIR4</accession>
    <name>E3QIR4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">4'-phosphopantetheinyl transferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_05896</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094772.1">
        <property type="nucleotide sequence ID" value="XM_008096581.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIR4"/>
    <dbReference type="GeneID" id="24411261"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05896"/>
    <dbReference type="eggNOG" id="ENOG502S2QX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1885607_0_0_1"/>
    <dbReference type="OrthoDB" id="15433at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="entry name" value="4'-phosphopantetheinyl transferase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="4'-phosphopantetheinyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ30752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="135" mass="14774" checksum="E8A50DBA8D85DD97" modified="2011-01-11" version="1">MYIYTATTTIIISFATRRQYSITGPPTLTRTCNNETDKEARFAAKEATFKAHPFRRLSFHDITIVRRALVEGKANPNGSGPPVAIIRGEREGEPGQTAMVSISHDGDYATAVCLGFEPETRDGKRAPGDEDEGVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIV7</accession>
    <name>E3QIV7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05939</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094815.1">
        <property type="nucleotide sequence ID" value="XM_008096624.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIV7"/>
    <dbReference type="GeneID" id="24411304"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05939"/>
    <dbReference type="eggNOG" id="ENOG502T4PV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1372103_0_0_1"/>
    <dbReference type="OrthoDB" id="4824913at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="199" mass="22534" checksum="FDA9BC4E07B5E9A1" modified="2011-01-11" version="1">MCNETTALCGSCGLERHIHYHRCIAWLWSYRQIKWGFTTPLGSIPKPKNCPFLDGEVKLEIQPGRCPNVQCPGHMIKVEMDRVSTDTRAAADKIEEQRIKLGLRMRTRPQGFQDPLEVGRPHQRKIPVVILDRRPDEGSGKSQGKQVVEEEEGQESQNEMSSPEQEYAGGIGIPVRSPVTRASAPRQRTFNGLMMMRPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIY6</accession>
    <name>E3QIY6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_05968</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094844.1">
        <property type="nucleotide sequence ID" value="XM_008096653.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIY6"/>
    <dbReference type="STRING" id="645133.E3QIY6"/>
    <dbReference type="GeneID" id="24411333"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05968"/>
    <dbReference type="eggNOG" id="ENOG502RPIZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004198_0_0_1"/>
    <dbReference type="OrthoDB" id="5422628at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="959"/>
            <end position="1082"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="868"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="980"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1040"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1069"/>
            <end position="1082"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ30824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1082" mass="123136" checksum="1A77DCD4FBAEFACA" modified="2011-01-11" version="1">MPTSTLNPPSEDGRIYTPPREQIPLSPLTPDLPGGEPEEEDVDMVDVGPEDTDAEADDEDKVMEETLGDGWLINWLKRDRATTAEDLRMIDYQGWRIHSPKVQLIRIKNFLADEDIDRTIDWERKFAEIGEFLQYCLHIKGGEGRDWWVDLHQCIDMLHTHRIFEQYHYGERKLVVDFPKYSGVSTRLPPLPDGRAIIAAKTPEDPVRPRYLLHRVPESVQDVDYQIPGPLLRIMFMTWFRQDGNLVWAADPNGPRPGSGQRGAVFQYQPDFNMALTEDEWFAKCMDGGPEATSGALRGEANFYILHNEYVAGEVGHVDDRHGRPHATQKFYPEGEAQQRFARYRGAKRAALQQCLSHFDSVENVAIQSPFRKLVLPLTRRQRERAEAEAGVNIVYKPLAVKAPPEDAKLDPLALVYWHAKLRENHATRAAGLREKVVAAHRRHAKENDTVLLPHNFLGPVTPFYLLRESERRLVARHALLVTLRDRVKRAWARNPRQMLEGVVKNMELGLEGRPSWNMKDELVAHREEHDGYLEMNDRELYWVDFVCGPSTNVKMQREALPRLGRPFEVFTARVQALLDEPSQECLFAVSKRSVSLQQVTLALNASLRHGDYVFSEDMVNMYSRVLADHGRLGYERAETGEVNISRPECTWHPEHRMNWPVDDDDWDPTTNPWTAANVPTPEHTWDWETAFVNVDKVDATRRATKRMLWSAAYRAGVELSTLAPRVVDLDRRLSRPASRDRRAAQLQAMAGEWQSEFERPEESGARPASYVSVVRQGHPRRWKKGMTEERAVEIVRRGMIDELSAGNSTLWPSRPRFGRGADGKDVMTLHRERVWAWARPEAAGPKKKKRFFSVNRWPVHLQSEKTQAAIRTSLADEEAERDREEEEVRAEMARAASRAQPTREELQKAEVARSLSVPYHEVNDAQTQFFPGHGEYWEGDTPLQKGVIKAHVQRVIQEELGPNDGKAPRGTSWLGGGRAKASSSSSSSSRRDRDGGGEVFGLPDVEPEVVPRSVPAGSAASATGQVAAEEGAVLDRLPRPTPPPPPPPRVIERRRPLLSPRYPPGQEGQRRVRFQDEEGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJC5</accession>
    <name>E3QJC5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_06107</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ30963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094983.1">
        <property type="nucleotide sequence ID" value="XM_008096792.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJC5"/>
    <dbReference type="GeneID" id="24411472"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06107"/>
    <dbReference type="eggNOG" id="ENOG502SUUV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2049526_0_0_1"/>
    <dbReference type="OrthoDB" id="1077582at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180507" description="Secreted protein" evidence="1">
        <location>
            <begin position="31"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="120" mass="13511" checksum="5FAC42A2B8A53A7C" modified="2011-01-11" version="1">MAAIIFAWPVGWFFLLVRPVLLPRPVTVTAHTTSILLLDEGKPYGSRPTTGATLGCQRRISFGLGCNMRTLVFWFVDWSMSEILRILLRTLRSLAHGIHSFAPDKRTVLPSPWTSPELAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJL1</accession>
    <name>E3QJL1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zinc transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_06193</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Functions as a zinc transporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endoplasmic reticulum membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ31049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095069.1">
        <property type="nucleotide sequence ID" value="XM_008096878.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJL1"/>
    <dbReference type="STRING" id="645133.E3QJL1"/>
    <dbReference type="GeneID" id="24411558"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06193"/>
    <dbReference type="eggNOG" id="KOG1484">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013430_11_2_1"/>
    <dbReference type="OrthoDB" id="78669at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006882">
        <property type="term" value="P:intracellular zinc ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904257">
        <property type="term" value="P:zinc ion import into Golgi lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1510.10:FF:000014">
        <property type="entry name" value="Cation efflux protein/ zinc transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045316">
        <property type="entry name" value="Msc2-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45755">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45755:SF4">
        <property type="entry name" value="ZINC TRANSPORTER 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="299"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="363"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="391"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="10">
        <location>
            <begin position="195"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="132"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="326"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="56"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="132"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="326"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU369017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ31049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="529" mass="58809" checksum="C4003CD4B089976D" modified="2011-01-11" version="1">MASSYALPSSALPHAHHHHMHSHSHSPPSLHALKSTMSNGGLHSHSQSQDSTGSGHAHDHGPSHSHTHDGHSHCRTNSSQFSIPRGKAPPQSLATMEGWKTEITPSGRQLLTPTTGSFSATFQPLDETKIVHQQNHHHEHDHSHGYCDKHHHHDHSHAHSHDHAKPSLFTRALLKYTPAVPVLHTILVEKDSRRIFYFMILNFSFMAVQAFYGYVTDSLGLLSDTIHMFFDCFALFVGLCAAVTSKWPQSQRFPFGLGKIETLSGFANGILLMLLSVEIIVEAFERIWEGQELHRLRELLIVSFLGGVINLLGLWGFGHHHHGHDHGHGHSHSHDGHDHGHDDSHEKKHSHGHSHHNDNMEGIFLHVLADTMGSASVVLSTILTYYTGWTFWDPLASCAIAILIFLASVPLIKSSARNLLLNVPDDVEYNLRNTLAGILQQKGVVNYSVPKFWMDDRGNEGSGDKLRGIVHVVAGRGASLDEVRDRVREHLLKNSMDIVVQVEREGDASCWCGVGRSTRLATMPLKRTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QK14</accession>
    <name>E3QK14_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Succinate-semialdehyde dehydrogenase</fullName>
            <ecNumber evidence="8">1.2.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_06346</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5 8">
            <text>succinate semialdehyde + NAD(+) + H2O = succinate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13217"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57706"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 8">
            <text>succinate semialdehyde + NADP(+) + H2O = succinate + NADPH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13213"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57706"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Amino-acid degradation; 4-aminobutanoate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.16" evidence="8"/>
    <dbReference type="EMBL" id="GG697353">
        <property type="protein sequence ID" value="EFQ31202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095222.1">
        <property type="nucleotide sequence ID" value="XM_008097031.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QK14"/>
    <dbReference type="STRING" id="645133.E3QK14"/>
    <dbReference type="GeneID" id="24411711"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06346"/>
    <dbReference type="eggNOG" id="KOG2451">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_5_1_1"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="UniPathway" id="UPA00733"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004030">
        <property type="term" value="F:aldehyde dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004777">
        <property type="term" value="F:succinate-semialdehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036243">
        <property type="term" value="F:succinate-semialdehyde dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046394">
        <property type="term" value="P:carboxylic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009450">
        <property type="term" value="P:gamma-aminobutyric acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07103">
        <property type="entry name" value="ALDH_F5_SSADH_GabD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000026">
        <property type="entry name" value="Aldehyde dehydrogenase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000004">
        <property type="entry name" value="Succinate-semialdehyde dehydrogenase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000005">
        <property type="entry name" value="Succinate-semialdehyde dehydrogenase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050740">
        <property type="entry name" value="Aldehyde_DH_Superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010102">
        <property type="entry name" value="Succ_semiAld_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01780">
        <property type="entry name" value="SSADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353">
        <property type="entry name" value="SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353:SF5">
        <property type="entry name" value="SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="9">
        <location>
            <begin position="24"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00050387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00052698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ31202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="491" mass="52334" checksum="11FCBB0ACD83C3B9" modified="2011-01-11" version="1">MASGAHQLKDASLLKTSCYVNGQWVGAASGKVFSVENPSTLAEVGKCPEFDEKDTEASILAAHDAFKSYRRTPARTRARLLRKWYDLMTEHAEDLATIIALENGKPMSDARTEVAYAASFYEWFSEEAPRIYGDTIQASNPSCRLVTLKEPIGVCGLIAPWNFPAAMITRKVGPALAAGCTVVVKAPAEAPLTALALAELAHRAGIPAGVVNVITALDNTVSVGKVLTTHPIIKKVSFTGSTGVGKLLMNQCSTTLKKLSFELGGNAPFIIFEDADLDAALKGLIASKFRLSGQTCVCANRILVHSKVYEKFSQMLVDAVKSFVVGDGFGEKTTHGPLIHGRAVSKVDEHVKDAVSKGARVLLGGKPRTDLGPNFFDLTVLADMKPGMKVCSEETFGPLAALFAFETEEEAIALANDADVGLAGYFFSKDVSRCWRVAEALEVGMVGVNIGAISDPAAPFGGVKQSGFGREGSKYGIDEFLVTKMVMTGIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QK81</accession>
    <name>E3QK81_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">DUF221 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_06413</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CSC1 (TC 1.A.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697354">
        <property type="protein sequence ID" value="EFQ31269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095289.1">
        <property type="nucleotide sequence ID" value="XM_008097098.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QK81"/>
    <dbReference type="GeneID" id="24411778"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06413"/>
    <dbReference type="eggNOG" id="KOG1134">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009187_1_0_1"/>
    <dbReference type="OrthoDB" id="2150324at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005227">
        <property type="term" value="F:calcium-activated cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045122">
        <property type="entry name" value="Csc1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003864">
        <property type="entry name" value="CSC1/OSCA1-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027815">
        <property type="entry name" value="CSC1/OSCA1-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032880">
        <property type="entry name" value="CSC1/OSCA1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018:SF149">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11660)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018">
        <property type="entry name" value="PROBABLE MEMBRANE PROTEIN DUF221-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14703">
        <property type="entry name" value="PHM7_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02714">
        <property type="entry name" value="RSN1_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13967">
        <property type="entry name" value="RSN1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="383"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="426"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="471"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="590"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="648"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="673"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like N-terminal transmembrane" evidence="10">
        <location>
            <begin position="26"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like cytosolic" evidence="11">
        <location>
            <begin position="197"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like 7TM region" evidence="9">
        <location>
            <begin position="377"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="861"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="941"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="890"/>
            <end position="906"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ31269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="994" mass="111860" checksum="3815A92579C103DA" modified="2011-01-11" version="1">MSEDAGKQLLNLIKNPYSQQLQKNSIWAALGTSLGVTIGIALTFSLLRPYNQSVYAPKLKHADEKHAPPPIGKKIWSWIPPLWNTSEADLVHHAGMDATIFLRFIRMCLYMFCTISVFCLAILIPTYLANRTDGIDETWLDAITPIAVWGEAYWAQVAVAYMITFTVMGFLWWNYRKVMLLRRRYFESEEYQNSLHARTLMMYDIPKDKCSDEGIARIIDKVVPSSSFSRTAIARNVKDLPKLIEQHDHTVRKLEQVLAKYMKKPDQLPAARPMCKPSKKDPSFATYPKGQKVDAIEYLTQRIKELEIEIREVRLSVDKRSTMPYGFASYSDIAEAHNIAYASRKKRPNGAVITLAPRPNDIIWDNLPLSSSVRRWRRIVNNLWIAVLTFVWVAPNAMIAIFLINLDNLGNVWPAFQRELARDPSWWAIVQGIASPAITSLVYLVLPIIFRRLSMKAGDQTKTGRERHVMAKLYAFFVFNNLIVFSLFSAVWSFVSAVVSETNGNKSIDAWHAIIDQNLATTIFTALCKVSPFWVTWLLQRNLGAAIDLAQLWTLVYSFFVRKFSSPTPRELIELTAPPSFDYAMYYNYFLYYATVALGFSGIQPLVLPAATLYYAIDYWLKKYLLLYIFVTKTESGGMFWRVLVNRMLFAVFLSNCVFFLSAWARADWATHSQALAIAPLPILLIIFKVVCSRVFDDKIHYLSTTNISKHPEAGMQKETRLRSERLASRFGHPALYKPLITPMVHQKAQPYLHIVYKGRLSDGREVNSGDMMSVSGYSDTYALDPMSSGKPGKSANVPGFEFVSESNLDFEFYKNRAEFADEHGQGDLFGRDLDIMRPGTPGSMSDYGSRPGTPTGVQLQGGMTGQRRDISGQSGFSAYKPNPPAYMSPTASGRQSPTRLGSPQAGFTQQAMMGDRSRSPLYNINSNGSDTALVRNAAGMPVSAPTPGPTVGALGGGPRGYSGLPQADADSLDQDPSQYDYFRGSRRRPNDGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QK92</accession>
    <name>E3QK92_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RNA polymerase II degradation factor 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">GLRG_06424</name>
    </gene>
    <organism evidence="19">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
            <location evidence="3">Telomere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DEF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697354">
        <property type="protein sequence ID" value="EFQ31280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <sequence length="988" mass="102305" checksum="A3AC1332BA70343A" modified="2011-01-11" version="1">MSEVQTRPAASRGRGSGRGGRGGFASRGGRTSTRPNGDKYDSKMDADDATSFEDQGELGELKKQYGSKAPLIKELFPDWSEQDILYALQETDGDENLAVTRIAEGTISQWGEVTKKAPRSKAKDSTTAASNIDSSSARPARGGRNVADAGRGRGRNADRGGRGGGRGRPSNTAAPNGTRHAKDTAQPLSVPTEESNAWDTPKTDVKDAPAEDPWAPKETTEKPVAPATEAPKPAGPAPKTWASMLRQTAVPKPAPKPPKQEPAPKPAEPIEPLPPVAPAAEPTPEPETEPEPQPEPTPELPAEPAHEEPAPAEVPTVIEPEVALPPSKDQLTETNLEQVVDESHPPATATVASTAADSWDPRLNAASATATPISASQQQHQPIRPAVPTTNSGFAASAIKATTERGSRTPSYQRRVLDQEEAVRMPGNREVDRAAVQFGAFSLNEDDDIDGDREEPETRTQPPADSPVAHPRTSLPPAPQQAPVPEAIGAQKPAPGLPPPATAAAPTGTSAPTGNVVDFANAPFAGPAGAAPQAPAAQGMFRITLAPQPGSLLTDPPPPVPQPGAAPAQPYSRFGQTGPQEPSSFPQKSIDPFTQPNQPPSASQSQFDGFPNQPSQQNQQPGGAFSSAPSEYSSYYTADQQNRPPYNYYNQPYGQQGAQGHQDSVSSQQRSFGGYNASQADNLSQYPQSGGLQNQSRYGGVTNDAQNSGHTTPNPTAQSQQAASQASQPQSHGQQSYPYNSHPYYNNAYYSNYMNYGHYGQGGYGGAPYGKGGVYGHPYGMSPQGPYDHASSPAAGFGQSSLHRADSGLSSGLAGGDFGGRAGSAQSGAQPGLAGSGFGGVQDTFGRGSSSYQSPAGQGFNSTAQPNNTASANDDLKPFGDGKPGAGPSPSLGGARPGSATNTASGQTGLPPPQSASQMGGYGGYPSHLQGHGLHGSSGYGMGGATTGQHGSAPFGSYGQQQQGGYGSGYYGSGNQQQQRGGWGGNYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKQ7</accession>
    <name>E3QKQ7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Homoserine kinase</fullName>
            <ecNumber evidence="3">2.7.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">GLRG_06589</name>
    </gene>
    <organism evidence="19">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Commits homoserine to the threonine biosynthesis pathway by catalyzing its O-phosphorylation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-homoserine + ATP = O-phospho-L-homoserine + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13985"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57590"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.39"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:13986"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GHMP kinase family. Homoserine kinase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.39" evidence="3"/>
    <dbReference type="EMBL" id="GG697355">
        <property type="protein sequence ID" value="EFQ31445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_008097274.1"/>
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    <dbReference type="GeneID" id="24411954"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06589"/>
    <dbReference type="eggNOG" id="KOG1537">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041243_2_1_1"/>
    <dbReference type="OrthoDB" id="195231at2759"/>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00064"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004413">
        <property type="term" value="F:homoserine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016126">
        <property type="term" value="P:sterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000068">
        <property type="entry name" value="Homoserine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="entry name" value="GHMP kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00384">
        <property type="entry name" value="Homoser_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006203">
        <property type="entry name" value="GHMP_knse_ATP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000870">
        <property type="entry name" value="Homoserine_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00191">
        <property type="entry name" value="thrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20861:SF1">
        <property type="entry name" value="HOMOSERINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20861">
        <property type="entry name" value="HOMOSERINE/4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000676">
        <property type="entry name" value="Homoser_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00958">
        <property type="entry name" value="HOMSERKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="GHMP Kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00627">
        <property type="entry name" value="GHMP_KINASES_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 18" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="11" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="12" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="7" id="KW-0791">Threonine biosynthesis</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP kinase N-terminal" evidence="16">
        <location>
            <begin position="72"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP kinase C-terminal" evidence="17">
        <location>
            <begin position="267"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00054121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EFQ31445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="359" mass="38983" checksum="71C0C34BC401D529" modified="2011-01-11" version="1">MTKETFVIKTPSSSANIGPGFDVIGLALSVYLELHVTVDRSRTASSEPLNCRLTYEGQGEGTDDISLDPSVNLITRVALYVLRCHGQRMFPVETHVHIKNPIPLGRGLGSSGSAVVAGVMLGKEVGHLDHLDLDRLFDFCLMIERHPDNVGASLYGGFVGTYLRPLKPEDVQRIEIPLSEVLPAPAGGVDTGETPPEPPHGIGHHIKFPWAKEIKAIAIIPDFQVPTHLAREVLPPHYTRPDVTFNMQRIALLPVALSTSPPDPELIHLAMQDKIHQPYRQTLIPGLGQVVESMSPSTQPGFLGVCLSGAGPTILALATSNFEEIAESIIKILKENNADKNIGCQWKVLEPAEGTQVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QL68</accession>
    <name>E3QL68_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Extracellular serine-rich protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_06895</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697356">
        <property type="protein sequence ID" value="EFQ31606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095626.1">
        <property type="nucleotide sequence ID" value="XM_008097435.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QL68"/>
    <dbReference type="STRING" id="645133.E3QL68"/>
    <dbReference type="GeneID" id="24412260"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06895"/>
    <dbReference type="eggNOG" id="ENOG502S40X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053381_1_1_1"/>
    <dbReference type="OrthoDB" id="2331100at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00920">
        <property type="entry name" value="Cupredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052953">
        <property type="entry name" value="Ser-rich/MCO-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883:SF17">
        <property type="entry name" value="CUPREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883">
        <property type="entry name" value="SERINE-RICH PROTEIN, PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180534" evidence="2">
        <location>
            <begin position="18"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="218"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ31606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="249" mass="24119" checksum="4E56DE504A0DABE3" modified="2011-01-11" version="1">MHFSAMIVSALAAVAQAQSVHVVSVASSNNTLKFFPDKLNAPVGSMVQFQFRGGNHSVVQSTFDNPCVPISSMNSSAQGLFSGYQPVAASAAMGQIPVFTVQITSAKPMWLYCSQAKHCQNGMVMVINENSKANSTRTLENYAKAAKTVTQSQSPAGGSAGGSTGGSTGGSNGGSNGGSNGGSSGGSTGGGSASPSGSVGSGSGSGSGSGSETGSAGGSTPTTPVPAGAVSLSAPASLLLAVGAGFLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMI6</accession>
    <name>E3QMI6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_07218</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096094.1">
        <property type="nucleotide sequence ID" value="XM_008097903.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMI6"/>
    <dbReference type="GeneID" id="24412583"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07218"/>
    <dbReference type="HOGENOM" id="CLU_2941591_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ32074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="60" mass="6928" checksum="85839D5562190002" modified="2011-01-11" version="1">MQIASIPIATMTVREDNNGQLTFIASDDMWKNIGKRFEKQSHHEIASDLSRKILLIKTRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QN03</accession>
    <name>E3QN03_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Sodium/hydrogen exchanger family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_07385</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the fungal Na(+)/H(+) exchanger family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697360">
        <property type="protein sequence ID" value="EFQ32241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096261.1">
        <property type="nucleotide sequence ID" value="XM_008098070.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QN03"/>
    <dbReference type="STRING" id="645133.E3QN03"/>
    <dbReference type="GeneID" id="24412750"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07385"/>
    <dbReference type="eggNOG" id="KOG4505">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008635_5_1_1"/>
    <dbReference type="OrthoDB" id="5327978at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015385">
        <property type="term" value="F:sodium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120029">
        <property type="term" value="P:proton export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042391">
        <property type="term" value="P:regulation of membrane potential"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036376">
        <property type="term" value="P:sodium ion export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1530.20:FF:000015">
        <property type="entry name" value="Na(+)/H(+) antiporter 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004712">
        <property type="entry name" value="Na+/H+_antiporter_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31382">
        <property type="entry name" value="NA(+)/H(+) ANTIPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31382:SF1">
        <property type="entry name" value="SODIUM ION_PROTON EXCHANGER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0050">Antiport</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="10" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="219"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="253"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="336"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="371"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="417"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="13">
        <location>
            <begin position="25"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="484"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="574"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ32241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="583" mass="63446" checksum="BF3679F32F1BB0FB" modified="2011-01-11" version="1">MPTLALTNFNIVVGLLGGWISLFGLVSFLCKETYYLSEALISLLAGVAFSPSAANLIRPLDYAGTPANVEAVTLAFSRLVLGVQLVLAGVQLPSRYLRTQWKPMALLVGPVMTCMWLATSLLVWALTPRLPFLHALAIGACVTPTDPVLSNVIVKGRFADHNIPSELQNLIISESGANDGLGYPFLFFALYLIKYVGDGGHQASGGAGLAMGLWFGETWGYTIVLSVIYGAVVGWLAKILLRWAESHKYVDRESFLVFAISLALFIVGTCGMIGSDDVLACFIAGNAFTWDDWFRLETEDDSFQPTIDMLLNVTIFIWYGAVIPWDEFSRNDVIPIYRLIALGILVLLLRRLPFVFAVHRWIPQIEQAKQAVFVGFFGPIGVSAIFYLYVTIEFLHTLNEGGEPRADVAHMADAVRVIVWFLAVCSIVVHGLSIPLGKLGYYAPRTLSRGVSFMSGDGEDNPHPFRIRGRVFLPFGRSRSLGLEGPTAYDAESRAQSPSGNEGSRPIYRIGGSIIPQGPADAEGPGASASVLRRSGQPEQRFGPEDGDGAQTKAAGQHEAPAPAPPELPNRTIRFPDETRVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNE8</accession>
    <name>E3QNE8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">CoA-ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_07530</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697361">
        <property type="protein sequence ID" value="EFQ32386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096406.1">
        <property type="nucleotide sequence ID" value="XM_008098215.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNE8"/>
    <dbReference type="STRING" id="645133.E3QNE8"/>
    <dbReference type="GeneID" id="24412895"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07530"/>
    <dbReference type="eggNOG" id="KOG2799">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037430_1_1_1"/>
    <dbReference type="OrthoDB" id="1664372at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042709">
        <property type="term" value="C:succinate-CoA ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004775">
        <property type="term" value="F:succinate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006104">
        <property type="term" value="P:succinyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.261:FF:000001">
        <property type="entry name" value="Succinate--CoA ligase [ADP-forming] subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017866">
        <property type="entry name" value="Succ-CoA_synthase_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="SUCC_ACL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11815:SF1">
        <property type="entry name" value="SUCCINATE--COA LIGASE [ADP-FORMING] SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11815">
        <property type="entry name" value="SUCCINYL-COA SYNTHETASE BETA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01217">
        <property type="entry name" value="SUCCINYL_COA_LIG_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="ATP-citrate synthase/succinyl-CoA ligase C-terminal" evidence="4">
        <location>
            <begin position="127"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ32386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="278" mass="30640" checksum="BA3E459B06328C96" modified="2011-01-11" version="1">MIQQYPEQFRTFTLGYTRGITREIVESISKFLDASAKERDSLQRILGRLYKVFTAKDATLLEIGSLARSHDGTLTCLDVRVVFDDAASKRQVDVFSLRDVMHEISEEVEAEKYGLVYVKMDGNIGNVVNGAGLAMATNDAIALYGGSSANFLDAGGQATKHTMVKAFEIILRDERVKTILVNIYGGKSDRAWCNRWIIRCDMIAESIVGAAKQLGPLKVPMVVRLQGTNSELGLKILEEADLGLHTEADFGKAAEKAVELARGSEDLPTFKLLATDRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNS2</accession>
    <name>E3QNS2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Major facilitator superfamily transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_07699</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697362">
        <property type="protein sequence ID" value="EFQ32429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096449.1">
        <property type="nucleotide sequence ID" value="XM_008098258.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNS2"/>
    <dbReference type="GeneID" id="24413064"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07699"/>
    <dbReference type="eggNOG" id="KOG2504">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1481876_0_0_1"/>
    <dbReference type="OrthoDB" id="6499973at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF230">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12790)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="69"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="98"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="120"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ32429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="182" mass="19722" checksum="6BA97E88161E2D77" modified="2011-01-11" version="1">MPEDVELDAIESYTPGSSHRDPESSPLAWLCVFGSFLFLYPSYGFMQTVGTVQSHLQQNQLSAYSSSDLGWIIGIFMSLCLFLGIQTGPLMDAYGTKFLGPVSVALYVPVFFAMGECTEYWHFILCLGVLGGTAVALTATVAIAAVGKLFNRRKGLAMGVLYPGLRLEVSLYPCCCGRFCPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QP24</accession>
    <name>E3QP24_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GMP synthase (glutamine-hydrolyzing)</fullName>
            <ecNumber evidence="2">6.3.5.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_07626</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.2" evidence="2"/>
    <dbReference type="EMBL" id="GG697363">
        <property type="protein sequence ID" value="EFQ32612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096632.1">
        <property type="nucleotide sequence ID" value="XM_008098441.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QP24"/>
    <dbReference type="STRING" id="645133.E3QP24"/>
    <dbReference type="GeneID" id="24412991"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07626"/>
    <dbReference type="eggNOG" id="KOG1622">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014340_0_0_1"/>
    <dbReference type="OrthoDB" id="1724632at2759"/>
    <dbReference type="UniPathway" id="UPA00189">
        <property type="reaction ID" value="UER00296"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003921">
        <property type="term" value="F:GMP synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001674">
        <property type="entry name" value="GMP_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025777">
        <property type="entry name" value="GMPS_ATP_PPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11922:SF2">
        <property type="entry name" value="GMP SYNTHASE [GLUTAMINE-HYDROLYZING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11922">
        <property type="entry name" value="GMP SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00958">
        <property type="entry name" value="GMP_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54810">
        <property type="entry name" value="GMP synthetase C-terminal dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51553">
        <property type="entry name" value="GMPS_ATP_PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMPS ATP-PPase" evidence="9">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ32612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="225" mass="25169" checksum="28742794FD68B02C" modified="2011-01-11" version="1">MRFWLTTELYVLTSTSRAELFLGRPKGVTEPEKKRKIISGTFINLFEKEAENTPNAGAVEWFLQGTLYPDVIESLSFKGPSATIKAHHNVAGLPDTLELKLIEPLRELFKDEVRSFGRELGIHDDLIMRHPFPGPGIAIRILGEVTPERMAIARAADNIFISMIKEAGIYDQMSQSYAGLDTNGAPFEFDFNLLKISTRIVNEVEGVSRVVYDNTSKPPGTIELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QP75</accession>
    <name>E3QP75_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphoribosylaminoimidazole-succinocarboxamide synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_07807</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697364">
        <property type="protein sequence ID" value="EFQ32663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096683.1">
        <property type="nucleotide sequence ID" value="XM_008098492.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QP75"/>
    <dbReference type="STRING" id="645133.E3QP75"/>
    <dbReference type="GeneID" id="24413172"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07807"/>
    <dbReference type="eggNOG" id="ENOG502SKGN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011750_0_0_1"/>
    <dbReference type="OrthoDB" id="3057599at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021840">
        <property type="entry name" value="DUF3433"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37544:SF1">
        <property type="entry name" value="PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37544">
        <property type="entry name" value="SPRAY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11915">
        <property type="entry name" value="DUF3433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="317"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="431"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="465"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="611"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="651"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="727"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="763"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="76"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ32663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="884" mass="98056" checksum="27372A8DFA42E430" modified="2011-01-11" version="1">MYSRDARPDSFAQEQRGQYPPQFWSARTPSQQSSTPNTLRPHHATRQHYANDLEDPQQTISPPPDFVPRAPSPPSQQQQQQQQQQQQQAKPYYPNQSFPAPVVVGNMFDAEDPYVSPPAVRFNEAQLAVDEITNRVRSKGFRDELTIAANGSVTPGVDDTPYLRYALEALTREHGHNFSPPSSVPSPAAGNDGYHRVAGHLPDDLASQRISGDPESGFTPVVPVPSHARDSLHRQSRPQSHAADRPSVSLGTRIFSMSPPQSANPHHHQEQGPATGESSPKWLPISEKETVFPGMNKLDTIDEDRTMFPRLTYLPAILRLPSMAALVVMCVAMAACLVVAAVYSPIQPGLLTYGETIYSAKYFLFRLLPQIVAALIFVYTQCVAATTLRILPFAALSEDEPLRRRNALFQNMYPTTFLLPHLAGPVHVKMALAILWLGAFAIPLASASFTVILNEEVWYWSAVPGVVWTLVALYILVIGAVVLLAFFWRNRVTGLVWDPRSIADLSVMISRSNTRDSYRGSEVAENRSALRRILRNRIVDRLGYWMTDNNNQEAPWYGLGTEHSQGHTPSDHYDVKNESDRLSVTSHLIDEGRDGYIQTLYLPWCLRTGQVLFFVIAATVLFAALFVVSFLNRTSLIAGFLPGVPVAPTIAAFSAANFLYSFVPSFIGLLLYLAFQSIEQHVRILQPWADLNAKDGAPAGRSILADYAACLPLQSTLHAIRNGHWRVAALSLLAALFAFLPALAGGLFMALTTASVVRMYPSVPVFGVILALLVLYLAGLASLLVGRNQYRLPHAVTCPAEVFSFLANEDNAMDPAFQAAPRSAEKLRVYLGAGRRSTETAAQSTWMFGYWPGRDERRLGVRRQKHFAERLPFHERAPSRPFMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>E3QP89</accession>
    <name>E3QP89_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">GLRG_07821</name>
    </gene>
    <organism evidence="20">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="GG697364">
        <property type="protein sequence ID" value="EFQ32677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096697.1">
        <property type="nucleotide sequence ID" value="XM_008098506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QP89"/>
    <dbReference type="STRING" id="645133.E3QP89"/>
    <dbReference type="GeneID" id="24413186"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07821"/>
    <dbReference type="eggNOG" id="KOG0591">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_23_1"/>
    <dbReference type="OrthoDB" id="10250725at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044732">
        <property type="term" value="C:mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08217">
        <property type="entry name" value="STKc_Nek2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000697">
        <property type="entry name" value="G2-specific protein kinase nimA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000525">
        <property type="entry name" value="Serine/threonine-protein kinase KIN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050660">
        <property type="entry name" value="NEK_Ser/Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43671">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE NEK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43671:SF13">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE NEK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-0132">Cell division</keyword>
    <keyword evidence="16" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0498">Mitosis</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="18">
        <location>
            <begin position="8"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="388"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="517"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="683"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="294"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="390"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="420"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="526"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="561"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="608"/>
            <end position="622"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EFQ32677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="716" mass="79771" checksum="86617E96D47D8FC2" modified="2011-01-11" version="1">MTLEADKYEVLEKIGHGSFGVIRKVRRRVDGLVMCRKEISYLKMSQKEREQLHAEFQILSTLRHQNIVGYYHREHLKSSQDLHLYMEYCGNGDLGRVIRDLAVKGQRAQESFVWSIFSQLVTALYRCHYGIDPPEVGSNVLGLFSTASKPKPPPGTMTILHRDLKPENVFLGEDNSVKLGDFGLSKMIQSHDFASTYVGTPFYMSPEICAAEKYTLKSDIWSLGCIIYELCAREPPFNAKSHFQLVQKIKEGKVSPLPSCYSSELMGTIKDCLRVNPDHRPDTAQLLNLPVVRLMRKEREVVELNKVVKTKEESLARRTKELEDKMAAFEADKASVRQEVDSSLRREWEVKARLEIDRQINTEIEALRKRFESEVQARVEAELQKRAVESAQSQDLGSSLTKSEYPRSSVGNGSGDEELSTSTDLTDVSTDSPLTNKKVTRTPFGRAQTMFVGGMGTPMDIEMASPSPINIASLSLSPRRTAATRVPNLNSGNIFSEDTGASSDPMWDLRDNISIDSDDEDIVPSPTRNIKSRQNPFTSKDRPVLSSQKSVPVVARVKPQFSATGPNQNKTLPTLPSMASNPDLGRGLRERNQSPHRRLTKIPSAANLTSTSGGSESPGGLSRKNSTKKDQEPLGKLAAKNNIKGRTLVELQQARAGGRPLSAVMSGGENLSPKRAFKDRMAERRASGGEPVAVWDPERDEMPSPFLVRRKPMARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPC9</accession>
    <name>E3QPC9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">phosphoserine phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">O-phosphoserine phosphohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_07861</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 3/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the HAD-like hydrolase superfamily. SerB family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.3" evidence="4"/>
    <dbReference type="EMBL" id="GG697364">
        <property type="protein sequence ID" value="EFQ32717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096737.1">
        <property type="nucleotide sequence ID" value="XM_008098546.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPC9"/>
    <dbReference type="STRING" id="645133.E3QPC9"/>
    <dbReference type="GeneID" id="24413226"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07861"/>
    <dbReference type="eggNOG" id="KOG1615">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036368_5_1_1"/>
    <dbReference type="OrthoDB" id="27226at2759"/>
    <dbReference type="UniPathway" id="UPA00135">
        <property type="reaction ID" value="UER00198"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036424">
        <property type="term" value="F:L-phosphoserine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07500">
        <property type="entry name" value="HAD_PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000143">
        <property type="entry name" value="Phosphoserine phosphatase serb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050582">
        <property type="entry name" value="HAD-like_SerB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004469">
        <property type="entry name" value="PSP"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01488">
        <property type="entry name" value="HAD-SF-IB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00338">
        <property type="entry name" value="serB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43344">
        <property type="entry name" value="PHOSPHOSERINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43344:SF2">
        <property type="entry name" value="PHOSPHOSERINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12710">
        <property type="entry name" value="HAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01137">
        <property type="entry name" value="C1.6.1:_Phosphoserine_Phosphat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01136">
        <property type="entry name" value="C1.6:_Phosphoserine_Phosphatas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00029">
        <property type="entry name" value="phosphoserine_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0718">Serine biosynthesis</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="124"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="12"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="124"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="11">
        <location>
            <position position="277"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR604469-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ32717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="493" mass="53828" checksum="661A37E37F9862B0" modified="2011-01-11" version="1">MADASPARSATSPRPQLSSSMRSSSFLREHQQYRPPQLPESRFGIDTVVEDLGKVAVSPSQQAHSYKQYAGFNGIPSEDNPPTIRHGLNHSYSHPNCAPAGGKKQSRLVATLFYKPNGESATAAAAATRSGGRVASPPKPTSEHSGGKESLPANFAPTQDPESFPLEPPTQEPEKLDHLYGSYVSPMCVTSFLHLMSTFPLPEGESDYSSSHRCLDSQDNPRVVELTLDPSPCQTYLSLTDLRRHELIYRFEREWSVDVALQPDTLWRHHPRLVVFDMDSTLITQEVIDLLAATIKDPPDLAARVADITHRAMLGELEFDAAFRERVQLLKGLPASFFEQLRPVLDVTKGVPRLIKALKRLGVKTAVLSGGFLPLTSWLAGELGIDYAHANEVVVDDAGRLTGEVKGLIVGKERKRDLLIEIAGKEGIDLSQVVAVGDGANDLLMMGAAGLGVAWNAKPMVQMEADTRLNSESLLDLLYLFGFTGDEIEQLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPL0</accession>
    <name>E3QPL0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF8213 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_07931</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697365">
        <property type="protein sequence ID" value="EFQ32787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096807.1">
        <property type="nucleotide sequence ID" value="XM_008098616.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPL0"/>
    <dbReference type="GeneID" id="24413296"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07931"/>
    <dbReference type="eggNOG" id="ENOG502SN55">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_146191_0_0_1"/>
    <dbReference type="OrthoDB" id="3660917at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058526">
        <property type="entry name" value="DUF8213"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26641">
        <property type="entry name" value="DUF8213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179904" description="DUF8213 domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="DUF8213" evidence="2">
        <location>
            <begin position="30"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ32787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="155" mass="15480" checksum="9213734C78605591" modified="2011-01-11" version="1">MLPSVSFLLALCPLVALAAPSALPFELEKRDITCLKVGATATAKWTNSTGQTCTFTGVVGSNYGANGAGSGDYSCNGRCGAGCTGSSLGNAYTQDCFSHDICSYFNNASGGASDPNCGAAFIAAVDDTILGVIAGCGQTNPSNAVSKPSTEPICS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQ59</accession>
    <name>E3QQ59_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitochondrial thiamine pyrophosphate carrier 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">GLRG_08141</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697366">
        <property type="protein sequence ID" value="EFQ32997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097017.1">
        <property type="nucleotide sequence ID" value="XM_008098826.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQ59"/>
    <dbReference type="STRING" id="645133.E3QQ59"/>
    <dbReference type="GeneID" id="24413506"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08141"/>
    <dbReference type="eggNOG" id="KOG0036">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_2_2_1"/>
    <dbReference type="OrthoDB" id="270584at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000016">
        <property type="entry name" value="Solute carrier family 25 member 23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24089">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0106">Calcium</keyword>
    <keyword evidence="13 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="EF-hand" evidence="16">
        <location>
            <begin position="20"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="16">
        <location>
            <begin position="58"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="16">
        <location>
            <begin position="94"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="16">
        <location>
            <begin position="125"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="380"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="498"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="605"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="258"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="339"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="258"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="281"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="297"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="345"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="356"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EFQ32997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="698" mass="75953" checksum="091A2B80CF1AAF1A" modified="2011-01-11" version="1">MGVTEWVAERRMEVDESQNQRDKRVEDLWRQLDPNGSGHLDFKGLQKGLKKIDHPMKNADDMLRKIMSVVDTNRDGKIQYEEFRYFVEQTETQLMILFQSIDKDNDGRLDKTELQEAFRRAGLVVPMRKLGAFFGDMDMNNDGYISFEEWRDFLLFMPTPNSHAPLKAVLEYYSSIVTLSAEGDSMVSEETLESSGTTGFLLQTLFGSILRIASLSSDREPGATDEPLTDINGRPVVVAVPSQEEAASPLPGLAQLPASTTQQQRQPRGNSTHNGSFASYTDSPSASQQQTPSTRPMVSSISPPGYSGTSANMNNMNMEAAVLQACIEAADEKRAGILPRLPGVGTSQANRVTGDSSEQGSSSSSDATVAPKTKRLTDLAPDPGYFIAGAVAGGLSRTATAPLDRLKVYLLVNTRASTETAATALKQGRPLLALRNAVRPFSDAVKDLWKAGGIRSLFAGNGLNVIKIMPESAIKFGSYEAAKRTLSKLEGHNDPTNINSYSKFVAGGVAGMVAQFCVYPLDTLKFRLQTSTVQGGLSGNALVLDTAKKMWQAGGVRIAYRGVTMGLLGMFPYSAIDMGTFEFLKTSYKKYMSKYRGIHEEDVKPGNIMTGIIGATSGAFGASVVYPLNVLRTRLQTQGTVMHPATYTGIVDVAQQTLKNEGMRGMYKGLTPNLLKVAPALSITWVVYENSKRLLGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQN3</accession>
    <name>E3QQN3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="13">AARP2CN domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_08315</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the TRAFAC class translation factor GTPase superfamily. Bms1-like GTPase family. BMS1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697368">
        <property type="protein sequence ID" value="EFQ33171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097191.1">
        <property type="nucleotide sequence ID" value="XM_008099000.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQN3"/>
    <dbReference type="STRING" id="645133.E3QQN3"/>
    <dbReference type="GeneID" id="24413680"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08315"/>
    <dbReference type="eggNOG" id="KOG1951">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002486_0_0_1"/>
    <dbReference type="OrthoDB" id="10260897at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034511">
        <property type="term" value="F:U3 snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000480">
        <property type="term" value="P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000472">
        <property type="term" value="P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000232">
        <property type="term" value="P:regulation of rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd01882">
        <property type="entry name" value="BMS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000105">
        <property type="entry name" value="BMS1 ribosome biogenesis factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012948">
        <property type="entry name" value="AARP2CN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039761">
        <property type="entry name" value="Bms1/Tsr1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037875">
        <property type="entry name" value="Bms1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007034">
        <property type="entry name" value="BMS1_TSR1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030387">
        <property type="entry name" value="G_Bms1/Tsr1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12858">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12858:SF2">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BMS1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08142">
        <property type="entry name" value="AARP2CN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04950">
        <property type="entry name" value="RIBIOP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00785">
        <property type="entry name" value="AARP2CN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01362">
        <property type="entry name" value="DUF663"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51714">
        <property type="entry name" value="G_BMS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Bms1-type G" evidence="12">
        <location>
            <begin position="65"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="394"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="523"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="617"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1086"/>
            <end position="1148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="423"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="452"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="467"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="489"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="523"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="560"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="573"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="622"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="677"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1086"/>
            <end position="1126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="1138"/>
            <end position="1148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00061391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ33171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1148" mass="131290" checksum="ADCEC4E78CE1879B" modified="2011-01-11" version="1">MEDQVHKPHRKSKDKKNKQHTGEKNPKAFAFSNPGKLARSAARSSDIKERRFHVPQVDRLPDEPPPRLVTIVGPPGVGKTTLLKSLIRRYAKETLSDPQGPITVVTSKKQRLTFVECPNELEAMVDMAKIADIVLLMIDGNYGFEMETMEFLNILAATGMPGNVFGILTHLDLFRKPQALKDAKKRLKRRLWSELYQGAHLFYLSGVMNGRYPDREVHNLSRFLSVMKNPRPLIWRNSHPYTIIDSYRDITHPTKIEEDPKCDRSVVLSGYLRGTNFASQGQRIHVPGLGDFTVANLEVLPDPCPTPAMEQAIAKVTGKTTRRRLDEKEKKLHAPMSDRSGLKIDGDAIWITREKGFTFDRDAEEGEMGEGEELIVGLQGERRLLGQTEEGVQLFKGGEQIKQVPEEEDTGRKTHRHARFADRDDDSEVEVDDEGFVSGEEDGESDVEEEFSEGKLGKMFRKNTEKEADEDDIAFADSDSDLGSLSGLEDGDEDDEGMDDSDFNSDEEAAAMKWKENMAERAKKLHGKRRSYHTPDLARYMYEDSLTPEEALQKWRGNDQDEEDIEADEEDDFFQKSKQDKEDKVEDRSIPQYDYEDLAAKWSQAANVEALRKRFTTAGLRDDEEDDGDEEDEFDGIDDEGEDDEGDGVFEDLETGEQHGAENSAEQEPAEEAFDDEREKNAKRKEELKLRFEEEDREGFMNDKANARREGGDQEFGEDDWYEAQKAVIQKQLDINKAEFETLDERQRTAVEGYRAGKYAKIVLEGVPSEFVTKFNPRNPIILGGLSPTEDRFGFVQVRIKKHRWHKKILKTNDPLIFSLGWRRFQTLPIYSISDSRTRNRMLKYTPEHMHCFGTIYGPLIAPNTGFVCFQSFSSANPGFRIAATGTVLSVDESTEIVKKLKLTGTADKIHKNTAFIKGMFNTSLEIAKFEGASIKTVSGVRGQIKRALSKPEGHFRATFEDKILYSDIVFLRAWYPIKPHRFYNPVTNLIGWQAMRLTGEVRRAEGIETPLQKNSQYRKIERETRHFNPLRVPRALAAELPFKSQIVQARKQKKDTYMQKRAVVLTKEEKTARNLLQQLSTIRNDKVAKRAAKKEEKRAEYRKKLAESEEKKEAREKKESKEFWRKNGRKRQAPDEGAGGGGQKRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>E3QR50</accession>
    <name>E3QR50_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Beta-ketoacyl synthase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_08482</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697369">
        <property type="protein sequence ID" value="EFQ33338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097358.1">
        <property type="nucleotide sequence ID" value="XM_008099167.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QR50"/>
    <dbReference type="GeneID" id="24413847"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08482"/>
    <dbReference type="eggNOG" id="KOG1202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_31_0_1"/>
    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05195">
        <property type="entry name" value="enoyl_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049552">
        <property type="entry name" value="PKS_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF50">
        <property type="entry name" value="HIGHLY REDUCING POLYKETIDE SYNTHASE SRDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22621">
        <property type="entry name" value="CurL-like_PKS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21089">
        <property type="entry name" value="PKS_DH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="11">
        <location>
            <begin position="11"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="12">
        <location>
            <begin position="968"/>
            <end position="1268"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="10">
        <location>
            <begin position="2532"/>
            <end position="2610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="453"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="8">
        <location>
            <begin position="968"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="8">
        <location>
            <begin position="1117"/>
            <end position="1268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="2428"/>
            <end position="2449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="456"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="8">
        <location>
            <position position="1000"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="8">
        <location>
            <position position="1182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ33338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="2617" mass="281097" checksum="E69828D386C8561D" modified="2011-01-11" version="1">MTPSQHNHDPHEPVAIVGMGCRWPGGVHDSSQFWEFLCNKTNGWKEFDEPRFSTSGFYHPNPDRPGSISMKGAFLAKEDARLFDHAFFGMTGLEVETMDPSQRKLLEVSYEAIENAGETWDSVSGSRTGVFVGNFCLDHWMIQSRDWDNPRPYAFTGAGTSILANRISYIFNLQGPSLTVDTACSSSMYALHLAVNSIRAGDCDAAIVASANWIADPGVQIALDKLGALSASSRCHTFDARAEGYARGEGYGAIYLKRPSLAVADHSPIRAMIRGTAINSNGRTGGITRPSARGQEMVIREAYRSAGDLPFRDTSYFECHGTGTYVGDPIEVAALGRVFAPERSADDPLLVGSVKSNVGHGEGASALASIMKVVLSLENGAIAPLFDLQTRNPNIDFEGANVLPVTEVTPWPKDRPQRASINSFGYGGANAHCIIDHVNIVLPDYVAPGVYRRKTNGTQKGHTNGHTNATQQGEPREPLSVVHKPRSVASSNAATRQLVLLPLSAHTERSFESNLAALSRVVDKVPLANIAYTLSSRRSRFAQRSFCIVDRDSVAQGLGTPHKITRAPLQTANLGFIFTGQGAQWHGMGRELFEYRVFRSAIESLDRVLGSLANPPSWSLLSILSGDCQDAALIQTAEISQTVCTAAQIGLVDLLASWSIRPSGVAGHSSGEIAAAYAAGRITAAEAIVAAYLRGQAVARNSQKGAMLAVGLGLEQVARYLDGREDEVKVAAVNSPGSVTLSGEPAAIKDISAAMTTDGVFNRQLQTGGNAYHSHHMLPIGREYSEMLAKGLESVRGLGPDSARRRYDPTLWISSVTPAKSTAEFGDAASYWRANLESPVLFSEAVTRLLSRQDVPINVLVEIGPHPALKSPLEQIVKDAGKTVAYASTLKRQEDGRRSLLQCVGTLFGLNASVDLAAVNAVDSTDGTGLEHGHVSSDLPPYQYTYGGLNYHESRASKEYRFRSILRHDLLGSKVAGNAKLRPQWRNILRMKDVPWLGDHRLVPDAVLPAAAYVAMAVEAALRAHAESQTSDVKGFSLRNMDIKKSLAIPEDDYGVEILTSMELVDNATSQSPAWATFSISSVKRDTDEWTEHSTGRIKIHVEADEHTLDKHQVHHASRAVGAQLWYKKFLDIGLGYGPVFQPLSDIRVDPVSGATVATVDLKPSTLAGGESQYPVHPASLDGAIQLGLIACHKGRADEASTAFLPVQIPRLYISNGITQDVCTVTARGTRRGIRSAHLDLQMLGPDGEVLLSTENLRCVSYSSEARTADDDMTFSSPFTRLVWKPDIRMLTNRQARQLYPPPKQNVERAPLWGITNKVAHLIIFSIYESFGKLADGPKPSGEVGHFFDWIKRKAQNDDSDAMREARKLAADGSLLDKIEELVGQAGDVMEVKIAKLLHDHAGDILFERRTGMDVIIGAGLLTPLYQSGLLMTGIYPQLSHVLEGLAHANPNSRVLEIGGGTGGATRIAMRAFTGRNGVKAYRDYTFTDISAGFLSAARESMAEFRDMHFSVLDVETDPLEQGYDEQAYDLVIACQVLHATSSMHRTLSHCRSLLKPGGKLVLVETNQNFIVPGIVVGTFTGYWAGIPDGRVDAPFQGLPAWDSSLRDAGFSGLDLVLDDFPEPHNTTSVMVSTVLAEPPTRAPPPSAMVHLLRSGDGNGDGSAPSLVRHIAQELERQGFEVRTGPLDTAPGSVTPGSRVVALCDDKHLLVDASEQDLRVFQHLSRNASSMLVLTSCGAARGRNADGALLPGLLRVLQNENPASRYVSIDVDADNFDMEATEAEELARQIAHLEADLDHGSPAVDDGETGPDREFTWQDGCLWVSRHVPDGGFHSQYGLDGRKLKPELLPLATHDGGVRIAFETPGVPSSLYFTPYKELHRPLPPGYIDVAVEAVGVNSRDLDVWTGRLDGDHFSSEYAGVVASVGAGSSSHDFRVGDRVYGLGKGQFGNYTRVPAAFACKLAPEVDTTEAASMPLAYATAVYALDHVAHLRQGQSVLVQAGAGDVATASIILARTKGADVCVTAETAEQVSFLVDNLVVPASHVIEGHSLDRLRQAAQNTRRGGFDAVICASGSGGGGLPSALLEVLAPLGRLIDVGGRGGDSQTGPWVSLELLPPMATYSSIDAFAILDADPALGAELMESVGDYHRKGLIGPLPGLATVDVGRLSSAVRDVANNNTPGKLVASFQNPESLVRMATPAPAARFDPEACYVVTGALGGVGQSLVRWMADQGARHLALLSRRAASDVPGAKELVSSLADRHVQVECFACDVSKKAEVADVMQRISSRRPVRGVVHAAVSYLDLSFDKIQAPRWNEGLSAKVRGTKNLHEATLSMALDFFVMTTSALSLYAFATQGAYTAANGFQDAFARYRRRLGLPASTVSFSLIREATAVGSDTTTIDLFERNRATTLGESQFLKLLEPAFLDNRTSHDAADPTQWPGRQQDPLSSANLHTYLNPQAVSKRRREEASSTGVAPRWYGDARASLMMRASRDAQQLSEHLDGPPGEASLNTTALLRAEFAAAVGQGAAGRSSTVALVQGAIVKAVAEMLFVDVESIDPAKSVADLGVDSLIAAELRNWFLQALGANISMLDLLDPAVGISKRAADITDGALAQSSNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRM1</accession>
    <name>E3QRM1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">3'(2'),5'-bisphosphate nucleotidase</fullName>
            <ecNumber evidence="3 11">3.1.3.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_08788</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>3'-phosphoadenylyl sulfate + H2O = adenosine 5'-phosphosulfate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77639"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <dbReference type="EC" id="3.1.3.7"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:77640"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>adenosine 2',5'-bisphosphate + H2O = AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77643"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:194156"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="3.1.3.7"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:77644"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>adenosine 3',5'-bisphosphate + H2O = AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10040"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="3.1.3.7"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:10041"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10 11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.7" evidence="3 11"/>
    <dbReference type="EMBL" id="GG697371">
        <property type="protein sequence ID" value="EFQ33509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097529.1">
        <property type="nucleotide sequence ID" value="XM_008099338.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRM1"/>
    <dbReference type="STRING" id="645133.E3QRM1"/>
    <dbReference type="GeneID" id="24414153"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08788"/>
    <dbReference type="eggNOG" id="KOG1528">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033446_1_1_1"/>
    <dbReference type="OrthoDB" id="411145at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008441">
        <property type="term" value="F:3'(2'),5'-bisphosphate nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052829">
        <property type="term" value="F:inositol-1,3,4-trisphosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004441">
        <property type="term" value="F:inositol-1,4-bisphosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042538">
        <property type="term" value="P:hyperosmotic salinity response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043647">
        <property type="term" value="P:inositol phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000103">
        <property type="term" value="P:sulfate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016078">
        <property type="term" value="P:tRNA decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd01517">
        <property type="entry name" value="PAP_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.540.10:FF:000015">
        <property type="entry name" value="3',5'-bisphosphate nucleotidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.80:FF:000003">
        <property type="entry name" value="PAP-specific phosphatase HAL2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006239">
        <property type="entry name" value="DPNP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051090">
        <property type="entry name" value="Inositol_monoP_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01330">
        <property type="entry name" value="bisphos_HAL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43200:SF6">
        <property type="entry name" value="3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43200">
        <property type="entry name" value="PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 10 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 10 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="10">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="295"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR600760-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ33509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="356" mass="37637" checksum="F9C6038C378C4B06" modified="2011-01-11" version="1">MPSYAKELEVAQLAVQRASILTKRVFHEKAKGTVDKNDKSPVTIGDFGAQALIISALRHHFPDDEIVAEEEAAQLRSEPALRDQIWELVRTTKLDDSSAESFLGGAIESPESMMDLIDHGNSKGGAAGRIWAIDPIDGTKGFLRGGQYAVCLGLMVDGDVKVGVLGCPNLPVDDKAPLTADIGSNANDDTGYGVIFSAVLGQGATSRPLRTGTIAEGAHISMRPITEMSAATFCESVEAGHSAHDDQAQIAAKLGITKPSVRMDSQSKYGSIARGAGDIYLRLPVSATYQEKIWDHAAGDLIVREAGGQVTDIHGKRLDFSVGRTLANNKGVIAAPAAVHGDVLKVVQDVLSSKST</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSG3</accession>
    <name>E3QSG3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_08934</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697373">
        <property type="protein sequence ID" value="EFQ33790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097810.1">
        <property type="nucleotide sequence ID" value="XM_008099619.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSG3"/>
    <dbReference type="STRING" id="645133.E3QSG3"/>
    <dbReference type="GeneID" id="24414299"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08934"/>
    <dbReference type="eggNOG" id="ENOG502S2FQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050091_0_0_1"/>
    <dbReference type="OrthoDB" id="2596908at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180758" evidence="2">
        <location>
            <begin position="19"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="291"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ33790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="339" mass="36426" checksum="C3CC4F7E841C3F4D" modified="2011-01-11" version="1">MFWKVAVTTAVLASSVGAEIRPLSMDQTIEVRAVDVLERNYEDVANRYIEKRQTAAVDGVWIPKSEVTLNPDGSINMTAWEEETSQKCTDALSHLDQASNPSGTCICYNLPSLDAKSGVFEADLRLYKVSDANGAFSGIPPQNIQVGLSFNGASVSPISANNSGGSTGTTARRDVGFEAPWSTLQKRAVAPQLLQTYLFVGQIDPARMTASMSMSQLEALVMPTLTLTGVNVAGQTVSTNVSSNEAAFITGVFSKEVVKSDLAVAQAAVDQIVASLHNGTVAFVLPGVQILIFPVGLVVTSTWLFIGLSFYGLGTYERFNHAENYRRRRAVAGNTTKRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSJ4</accession>
    <name>E3QSJ4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tat pathway signal sequence</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08976</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697374">
        <property type="protein sequence ID" value="EFQ33832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097852.1">
        <property type="nucleotide sequence ID" value="XM_008099661.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSJ4"/>
    <dbReference type="GeneID" id="24414341"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08976"/>
    <dbReference type="HOGENOM" id="CLU_1922035_0_0_1"/>
    <dbReference type="OrthoDB" id="6499973at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF319">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ33832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="132" mass="14598" checksum="7D692D81825283A0" modified="2011-01-11" version="1" fragment="single">QVRKVGAMAIWTLFPAMAITPQYFLNRRGAATGLTVAGSSLGALVFPIVLSELLETVWFGWYVRICGFIMMPALIISSPTVRARPLRERVVSSSGRHSRNRSIFARSMTCVLCSLACSFYSSIYLRLASTMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QT03</accession>
    <name>E3QT03_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Beta-lactamase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_09135</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S12 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697375">
        <property type="protein sequence ID" value="EFQ33991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098011.1">
        <property type="nucleotide sequence ID" value="XM_008099820.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QT03"/>
    <dbReference type="STRING" id="645133.E3QT03"/>
    <dbReference type="GeneID" id="24414500"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09135"/>
    <dbReference type="eggNOG" id="ENOG502S0EY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2061330_0_0_1"/>
    <dbReference type="OrthoDB" id="5946976at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050491">
        <property type="entry name" value="AmpC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46825:SF15">
        <property type="entry name" value="BETA-LACTAMASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46825">
        <property type="entry name" value="D-ALANYL-D-ALANINE-CARBOXYPEPTIDASE/ENDOPEPTIDASE AMPH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="2">
        <location>
            <begin position="3"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ33991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="119" mass="12928" checksum="0E0E62A411ABFAE0" modified="2011-01-11" version="1">MEDWHAPGLTVAIIDGDKTWAKGYGYAVLNSTPMTPHTLFYTGSTTKSFTTAGLSLLIDNATANSSVYSGLTWKTPVSSIFRDDFVLSDDWATAHITVEDALSHRTGYPRHDLASAKTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QT54</accession>
    <name>E3QT54_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitochondrial export protein Som1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09186</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697376">
        <property type="protein sequence ID" value="EFQ34042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098062.1">
        <property type="nucleotide sequence ID" value="XM_008099871.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QT54"/>
    <dbReference type="GeneID" id="24414551"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09186"/>
    <dbReference type="eggNOG" id="ENOG502SG5C">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_142986_1_0_1"/>
    <dbReference type="OrthoDB" id="3983163at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042720">
        <property type="term" value="C:mitochondrial inner membrane peptidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024645">
        <property type="entry name" value="Mitochondr_Som1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11093">
        <property type="entry name" value="Mitochondr_Som1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="126" mass="14503" checksum="8B79F2F31B918BA1" modified="2011-01-11" version="1">MTPPCKVFPVSELELHVQANVKGKKRKLPRGADVDLTKCALKEMTQFRCYVDDSKSRDSPVRCWPIHRLFRQCRDKKGTFTIETTAWEGSIHSAQRTSPTTGSTKTEQGHNNDPVYHQWSQAWQDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTS6</accession>
    <name>E3QTS6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="10">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_09382</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>feruloyl-polysaccharide + H2O = ferulate + polysaccharide.</text>
            <dbReference type="EC" id="3.1.1.73"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the tannase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="10"/>
    <dbReference type="EMBL" id="GG697378">
        <property type="protein sequence ID" value="EFQ34238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098258.1">
        <property type="nucleotide sequence ID" value="XM_008100067.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTS6"/>
    <dbReference type="STRING" id="645133.E3QTS6"/>
    <dbReference type="GeneID" id="24414747"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09382"/>
    <dbReference type="eggNOG" id="ENOG502QPXZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014819_1_2_1"/>
    <dbReference type="OrthoDB" id="3039123at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030600">
        <property type="term" value="F:feruloyl esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011118">
        <property type="entry name" value="Tannase/feruloyl_esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938">
        <property type="entry name" value="FERULOYL ESTERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938:SF15">
        <property type="entry name" value="FERULOYL ESTERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07519">
        <property type="entry name" value="Tannase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="5 10" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005127936" description="Carboxylic ester hydrolase" evidence="10">
        <location>
            <begin position="17"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ34238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="424" mass="45716" checksum="5A85563AE7C42CB7" modified="2011-01-11" version="1">MLPLMLLGALAPGVRAVEPLAKANVTFEQQCSKFASSLQIPGADTTATEYIPAGTTLQLPGSDPSCARPSQNVTANLCRVTARIATSVRSGVKFEAWLPENWTGRFLSTGNGALGGCVQYEDLDYASSLGFAAVATNNGHDGMSGAPFMNNPGVIEDFAYRALTTGVVVGKDITKAFYNRPHTKSYYLGCSTGGRQGFKQAQAFPQNFDGIVAGAPAFSFNNLTSWSCHFLPLTGQQGADTFIPMSMWPTIHNDILDQCDELDGAKDGLLESPDLCDYKPESLLCGASSNQTAGCLTQKQVETLRGIYSPLIDASGSLVYPRMQPGAEMTGAPQVYFSGQPFSASDWFKYAILNDSNWDPATITSEDYVKASSLNLFNIETWDGDLSTFQQRGGKILHYHGLVDGIISSDNSLRYYEHVSQTML</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUX7</accession>
    <name>E3QUX7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytidine and deoxycytidylate deaminase zinc-binding region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09809</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697382">
        <property type="protein sequence ID" value="EFQ34665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098685.1">
        <property type="nucleotide sequence ID" value="XM_008100494.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUX7"/>
    <dbReference type="STRING" id="645133.E3QUX7"/>
    <dbReference type="GeneID" id="24415174"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09809"/>
    <dbReference type="eggNOG" id="ENOG502S00E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107695_0_0_1"/>
    <dbReference type="OrthoDB" id="9980836at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="1">
        <location>
            <begin position="39"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="224" mass="24846" checksum="7C2A853770D17B51" modified="2011-01-11" version="1">MADEALPPRDPETILSALLSLTEDRIVPLTRRGVSSGSKLFGAAILSSTTLEALTVATNDERASPLLHGEINCIQQFFTDVFPDPATRPSPRTACVFFATHEPCSLCLSGIAWSGFREVYYLFTYEDSRDLFAIPHDIDILDAVFRVRAEGEPDDALARRPLYNRANKFFTARSLADLVADLPEGEPRARWVRETERVKGLYNALSDTYQEGKKAGATSSSVWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QV40</accession>
    <name>E3QV40_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycolipid 2-alpha-mannosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_09874</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 15 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697383">
        <property type="protein sequence ID" value="EFQ34730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098750.1">
        <property type="nucleotide sequence ID" value="XM_008100559.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QV40"/>
    <dbReference type="STRING" id="645133.E3QV40"/>
    <dbReference type="GeneID" id="24415239"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09874"/>
    <dbReference type="eggNOG" id="KOG4472">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024327_0_0_1"/>
    <dbReference type="OrthoDB" id="439943at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000026">
        <property type="term" value="F:alpha-1,2-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000032">
        <property type="term" value="P:cell wall mannoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000051">
        <property type="entry name" value="Alpha-1,2-mannosyltransferase (Ktr4)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002685">
        <property type="entry name" value="Glyco_trans_15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31121">
        <property type="entry name" value="ALPHA-1,2 MANNOSYLTRANSFERASE KTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31121:SF6">
        <property type="entry name" value="ALPHA-1,2 MANNOSYLTRANSFERASE KTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01793">
        <property type="entry name" value="Glyco_transf_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="40"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="43"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="70"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ34730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="428" mass="50200" checksum="453A7CBB746F2D32" modified="2011-01-11" version="1">MATGSARYVRYLLFAFFGLAVFYFISHSSYEGARLQDGTFSKPGAPANGQQQSGQNAAEKPKQPAQSDANRPKVGETYDPKEWPMPMTPNEPGWDELSGIASGPRMNATFVTLARNSDIWDIARSIRQVEDRFNRRYNYDWVFLNDKPFDATFKKVTTSLVSGKTHYGEIPKEHWSFPEWIDQEKARKVREDMAQRKIIYGDSVSYRHMCRFESGFFFRQPLMMNYDYYWRVEPSIELFCDIHYDPFRFMKENNKKYSFVLSLYEYVETIPTLWDSTKKFIKNHPEHIAQGNSMGFLSDDGGDTYNHCHFWSNFEVGDLNWLRSQAYIDYFESLDQDGGFFYERWGDAPVHSIAASLLLPKDQIHFFNDIAYYHVPFTHCPTGEKVRLDRRCHCNPKDNFDWKGYSCTSRFFEVNGMEKPEGYENQQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QV63</accession>
    <name>E3QV63_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Mediator of RNA polymerase II transcription subunit 4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 8">Mediator complex subunit 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MED4</name>
        <name evidence="10" type="ORF">GLRG_09897</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the Mediator complex subunit 4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697383">
        <property type="protein sequence ID" value="EFQ34753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098773.1">
        <property type="nucleotide sequence ID" value="XM_008100582.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QV63"/>
    <dbReference type="STRING" id="645133.E3QV63"/>
    <dbReference type="GeneID" id="24415262"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09897"/>
    <dbReference type="eggNOG" id="ENOG502SCD7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057381_1_0_1"/>
    <dbReference type="OrthoDB" id="1929813at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019258">
        <property type="entry name" value="Mediator_Med4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10018">
        <property type="entry name" value="Med4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0010">Activator</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="123"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="258"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="168"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="193"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="259"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="307"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ34753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="334" mass="36903" checksum="F63391369EB11605" modified="2011-01-11" version="1">MDKVIDARFERVEKALAILIESVSKYHPHPKQALDLYEADNDLAKGLDEVQAHQNNHIRLQQLRATTSSLDTQIRETLQSLATTRKDITTTQITVYPDGPKYPVKYDELLNYARRISKTTLPPAALINGGSLTTGGGTPGPDLNASMTTNPNTPGANGLQSQPVSAVPTPSQSQTPGPSGAPNSSPLHDAHQGIQQTAATSGATSLPDGLRNHLNPHFNASFIPWPNEFQIRSGAMAVYQDLSDKGIDPRGYDPQQIAEAKRKEEEERRAREEQEKLENERKDREYREKMEKIRREQQEAYRRDSVAAGAGASSAGKSKQFQFTSLMDDDDDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVE1</accession>
    <name>E3QVE1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_09973</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697384">
        <property type="protein sequence ID" value="EFQ34829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098849.1">
        <property type="nucleotide sequence ID" value="XM_008100658.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVE1"/>
    <dbReference type="STRING" id="645133.E3QVE1"/>
    <dbReference type="GeneID" id="24415338"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09973"/>
    <dbReference type="eggNOG" id="ENOG502RAIK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_924414_0_0_1"/>
    <dbReference type="OrthoDB" id="5333491at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ34829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="301" mass="34338" checksum="6B0BDEBF7546A1E9" modified="2011-01-11" version="1">MPSLKSVKLSMDDDEKRFPDIRMRHRDEAAQAIRALSLPALTSVDLDFFLRRQRNERAQPPVLHNTGVPDPLSSSIFELSLNLVDLTVEGVFDGSLLRPIERLSTTSWPNMKFLEINLCITTPSGGWYFTKHDEVPFQPLYMPQSQIKTTHSDLHLEKFNFLKEAGYAYLDPVHVFRSKADDAELTPFIEAYAEALSMMPKLKSAALTVQLEDHIEGEPGWFCIAYFSPCKSAHDHPPRLICPRCNRGVTRQLVTSLLGWEPNEKLADKLRRTGAKFCTEPMVEKTMDEFRSYHGVEDDPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVK0</accession>
    <name>E3QVK0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_10032</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697385">
        <property type="protein sequence ID" value="EFQ34888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098908.1">
        <property type="nucleotide sequence ID" value="XM_008100717.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVK0"/>
    <dbReference type="STRING" id="645133.E3QVK0"/>
    <dbReference type="GeneID" id="24415397"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10032"/>
    <dbReference type="eggNOG" id="ENOG502SP3K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081631_2_0_1"/>
    <dbReference type="OrthoDB" id="3830579at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ34888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="227" mass="24977" checksum="D1CB591BDCF70B6C" modified="2011-01-11" version="1">MTVTEIGCCGIKPGLRIMDESTPEGKIYMGVYKKLNASPEGPHRMYLSVDLDEPFKVYSLFDWDSLEHHEKFANTFGEGVQEDFGKVLTHGEYTKHITPTPPLQEALESAVTDVFLVHCPSDISPDDKVTTELRGILKKGFGQHADVTAISYGWGVENDFPVYGIGGGMVGSVFSAFVGWASVEANTTCREAAAHTAIQESIRRLYGVEALKVLRSSCAVLERNDKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVN1</accession>
    <name>E3QVN1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">D-isomer specific 2-hydroxyacid dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_10063</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697385">
        <property type="protein sequence ID" value="EFQ34919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098939.1">
        <property type="nucleotide sequence ID" value="XM_008100748.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVN1"/>
    <dbReference type="STRING" id="645133.E3QVN1"/>
    <dbReference type="GeneID" id="24415428"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10063"/>
    <dbReference type="eggNOG" id="KOG0067">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019796_1_2_1"/>
    <dbReference type="OrthoDB" id="9991913at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030267">
        <property type="term" value="F:glyoxylate reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016618">
        <property type="term" value="F:hydroxypyruvate reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12168">
        <property type="entry name" value="Mand_dh_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000526">
        <property type="entry name" value="D-mandelate dehydrogenase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050223">
        <property type="entry name" value="D-isomer_2-hydroxyacid_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10996">
        <property type="entry name" value="2-HYDROXYACID DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10996:SF281">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE NAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase catalytic" evidence="4">
        <location>
            <begin position="120"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="5">
        <location>
            <begin position="173"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ34919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="391" mass="41652" checksum="53F99A401B58F28B" modified="2011-01-11" version="1">MAEPHNTPYPPATPQCQTPRSSPPRPHQAMTAGALTAGVAASATADGTHVKPRVLHIGDPIKYNPHAYAAFAARCEIIRPTTPERQRPAFAAALRDGKWGDFSAVFRPFWGTGGEMGNWDAELIPLLPASCRVFASAGAGFDWADTRLLGERGIIYCNSGLAAAEAVADFAVALVISTFRHLPWCMTAASDPAAFQDCHAGATAVSHSLRGHVLGLIGMGNIGQQVAQRLGLGFRMDVHYFDIVRKDAAMETVSDATFHETLESLLGVSDCVVLCTPAGGKMITAESLAWFKPGSRFVNVARGSLVDENALADALESGRIGSAALDVHADEPRPHPRLLRLAETKVMLTCHNAGGTVETHKGFEKLSMENIMAVLSGGKPITPVNLHHLKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWZ8</accession>
    <name>E3QWZ8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_10530</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697392">
        <property type="protein sequence ID" value="EFQ35386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099406.1">
        <property type="nucleotide sequence ID" value="XM_008101215.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWZ8"/>
    <dbReference type="STRING" id="645133.E3QWZ8"/>
    <dbReference type="GeneID" id="24415895"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10530"/>
    <dbReference type="eggNOG" id="ENOG502T81D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043689_0_0_1"/>
    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041068">
        <property type="entry name" value="HTH_51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050444">
        <property type="entry name" value="Polyketide_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45681:SF6">
        <property type="entry name" value="POLYKETIDE SYNTHASE 37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45681">
        <property type="entry name" value="POLYKETIDE SYNTHASE 44-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18558">
        <property type="entry name" value="HTH_51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase fungal type helix-turn-helix" evidence="3">
        <location>
            <begin position="14"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransferase type 12" evidence="2">
        <location>
            <begin position="203"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ35386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="378" mass="41526" checksum="5D7BAF973DF971C0" modified="2011-01-11" version="1">MSLDAYAVLDAFSDIKSRTDQSIAANNLDTYSSEFLPRSEDIAVAIFCNALEELGCPIRSAASGDKLSRVRPAAEHKRLVDYIYRVLEARAGLILDDGNHLTRTSKACPDSDIDSLLDSLLRDRPSQDAEIKLMQTIGKSYGKCLSGEVDAVQLLFDAAESRSLLNKLYATSDATNSLLQPLKTFIEEVAAGWSAPSQPLRILEVGAGTGGTTSVLLPTLARLGVPTVYTMTDISPSLVTQASSAFKQFPFVEFRVVDIEKEPPQELRCSQHIVLGSNVVHTTTNAQSSLKNIHKMLRPDGFLIFHELTMQMPWADVCFGLFEGWWRFDDGRQHALQSPQAWAKMLKSAGYGHADWTDGSRPEAKLQSLILGMASDIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QX10</accession>
    <name>E3QX10_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_10542</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697392">
        <property type="protein sequence ID" value="EFQ35398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099418.1">
        <property type="nucleotide sequence ID" value="XM_008101227.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QX10"/>
    <dbReference type="GeneID" id="24415907"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10542"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_13_1"/>
    <dbReference type="OrthoDB" id="4540492at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000134">
        <property type="entry name" value="MFS sugar transporter protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF31">
        <property type="entry name" value="HEXOSE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179999" description="Major facilitator superfamily (MFS) profile domain-containing protein" evidence="8">
        <location>
            <begin position="35"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="159"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="272"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="314"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="341"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="373"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="412"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="440"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="26"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ35398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="480" mass="52289" checksum="3ED4F2B8DDD6DBF7" modified="2011-01-11" version="1">MLRKTQTGTWLPAWVPESTLVLSLLLILCSFVQSCTVGYDTALLNAFNILPAYRDYFQLNAATTGLNTASIFIGGILGPMFAGVAADRLGRRPAMFWSSLVAIVGVLLQTAAQNIAMFIVGRIIIGLGASASGIAGGVYLSETFHSRFRAWGVGSLNDFYWIGAILAAGITLGTGSWTTSWAWRAPSLFQGIFSLLCIAILPFVPESPRWLQYQGHSDEARLAVAQTNADGDVSDPDVVVIYNEIVDSLTSEKEHDSSIADIVKNPVVRRRFLIGASVGPMSTVVGNLIALFYLGPELSSAGVTDSRTQLHVNVVLNVWCLVCCLLGTFLVTAWGRRPTAIAGQSLLTACLFVIGGLSKVYSDNGPERTPTSLVYGNVAVIFLFQGFYSLAWTPITYLYPTEVMNYSIRAKGLAFSSLMLSSLTLLLVFIMPIALENIGWKMYIVNGSWDVIILLIVVIFWVETKGKTLEEVDAIFYRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXA7</accession>
    <name>E3QXA7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">TPR/MLP1/MLP2-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_10639</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697394">
        <property type="protein sequence ID" value="EFQ35495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099515.1">
        <property type="nucleotide sequence ID" value="XM_008101324.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QXA7"/>
    <dbReference type="GeneID" id="24416004"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10639"/>
    <dbReference type="eggNOG" id="KOG4674">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001250_0_0_1"/>
    <dbReference type="OrthoDB" id="343070at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057974">
        <property type="entry name" value="NUA/TPR/MLP1-2-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012929">
        <property type="entry name" value="Nucleoprot-TPR/MLP1-2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057577">
        <property type="entry name" value="Nucleoprot-TPR/MLP1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18898:SF2">
        <property type="entry name" value="NUCLEOPROTEIN TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18898">
        <property type="entry name" value="NUCLEOPROTEIN TPR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25481">
        <property type="entry name" value="Nucleoprot-TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25785">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07926">
        <property type="entry name" value="TPR_MLP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleoprotein TPR/MPL1" evidence="7">
        <location>
            <begin position="183"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="NUA/TPR/MLP1-2-like" evidence="8">
        <location>
            <begin position="484"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoprotein TPR/MLP1-2" evidence="6">
        <location>
            <begin position="1067"/>
            <end position="1195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="93"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="935"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1043"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1082"/>
            <end position="1103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1203"/>
            <end position="1225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1425"/>
            <end position="1457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1511"/>
            <end position="1545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1589"/>
            <end position="1622"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1705"/>
            <end position="1750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1841"/>
            <end position="2126"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="149"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="223"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="421"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="570"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1631"/>
            <end position="1695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="93"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1050"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1082"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1434"/>
            <end position="1452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1511"/>
            <end position="1533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1536"/>
            <end position="1545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1592"/>
            <end position="1622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1732"/>
            <end position="1746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1873"/>
            <end position="1904"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1916"/>
            <end position="1933"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="1934"/>
            <end position="1949"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1966"/>
            <end position="2038"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="2046"/>
            <end position="2059"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="2070"/>
            <end position="2087"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF25481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF25785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ35495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="2126" mass="236452" checksum="D595B24F64929751" modified="2011-01-11" version="1">MAAAVDVAYVAGHLGVPESTVSTATTDPTPELVASLLEAVIAKAREHDELYAQKLQVDIELESAHHSAESRCQSFKATADKALKDVEEVRQKLKEEETKRQTVENELQSLKARGSDHDSELTTLRDRVESLQSSNRANMALLESRNARDSELSEELAKQHQKNVQLQKEITSLQQAVQSAQAAVSSSKYREESLQQQLDLARRNSEWFETELKTKSEEALKYRREKGARIAELQRQNEDAKSTIDSMKRTEQQLRDRLSAAQAKAEEALTKVQQQQEAFARSEESYKHEIESKQRVVDMTNQLADSHKARVQTLEGEKEALKEKHANEVRRLQQELERERENCRALEERVAQLEAELDELHARMEQAPPRGSTPTPQTPRMNGSFLGRPASPFATPASARSKSAITATQAIDELYKVKGQLAGEKRRNQQLAEELDNMIALLEAKTPEIEELQNEADTLRAEITRMSELSQTSFEERDVAKKSARKAEGALANAQAESKILRTQIRDLSTQIQMLVFNMHAREKGLEQLSREETIRLEQLSRGEVTEGALADMSDTHQFITQKFVVFKDIQELQAKNQELLRVTRELAEQMESEEAVAAKSQAVEDHQAVERLQQELANMIDETKSLRTTMESFKAERDMFRRLLQQKATAGELASILGSDDGQRLPLASIENGEGGDVSPHDALRALQVEFDTYRNDEESVRRSLREQIDRLSSEKNSLQGEVAKISSQITLASERYEMLHSNFVALQSENKELQKRNQSLSEDSIKHEIRTQQVAEELIDAKGLLESVRNEAANLKAEKKLWKDIQDRLNQDNENLMQEKTRLNNLLASQQSMLNERDISESEYRRKAQSKIDTLEQELSSTKRKLSDEMEEGKKLQLRKEFDARESQKRIDELSNSLSQIREEHVAVKTSRDHLQARVDELTIELRNAEERAGRLAPRPTPRPGTMAPPTQTDQETEAEVRELINEVSDLKRELDIAKSQLENAKEQTEQYKQLSEQNEEALSEFTASQEQYREEMEAALTSKDAKIKELEQRVEDLSTELASSNKELSHLRDSQAEVARKYEDEKTILDEEIKRLKEESERHAEAAKFHQQDLRAQSEITAKAQQDYEHELVKHAEAAKLVQQLRTEYNELKSQSATLRAEAESAKVALSQSESSWEERRQRLEQEMSEIKTRRDDVNAQNKLLHEQLESITKQFSALKEGRNASAEDAGNNAETGNDSAADGLRELNNYLRREKEILEVQYDLKVQESKRLQQQLEYSQSQLDEARLKLDQERRAQAESGQASIAHKDLMDKLNELNLYRESSATLRNELAQARTQISEKNAKIEELEGKVQPLEARIEELQTQKGFLEEEIKQVQEDRDRWQKRTEGILTKYGRVDPAEMEQLKQTINELQAERDALKESEAPLRAEIEETKQLLETERANWQNTRQRMTEQFKERSRKLTGEKNDAMTGRNEAIAEKDAAVAEKDQLQQQLHNANTELESTRQRLQVSTQQRTEFEQQIQSFQQQVQRLQQDDQAAQAQPGAQGAQPPTDASTSVSTQVVAQLEQQLAEMRSQLDAVSAQKAAAEQELENLRTQLQTVTSERDQAIQAAQQAAQSQTQTAPEPTGTNNAAALANGTNGLSDEERKALEDRVAAAEAKAAECERKANELEANITQTIKERSDKMRNALNEKLRQSREKLDEEFRTKLEQEKIIWKAENQAAAAPGQSADGQPAVPATPVKQQDPEATSATPMTGTPAGPTDLSQLPDAEIRKFLSTNPTVRSIMSSNLRKKLEEQTAKVKSETETSLKVEFEQRIASAREEGQMLAQKKSALQINMKDNQIRSANAKIEVVATAAAKTPQRPVGEVWEEAKVAKPAPAAPQTSPVKPAGNAQPTAQPAAPRPSISAPSGPPAQAGAAPNGKSYAKEEARQMTSSDCFQAAPNASTNQAPPPATAPSGIPPPGSGLPQKRQIPVPGGENKAAAAAATNALPANPFAAGAANGTQPQANPFAQGGQGQQQQNPFASSTQGGQAGQPGQQGQAQQQPATQGQTAPRSGIPLPGRGGAAGRGRGGTYAAGNRVSSGGAERGGMAGRGGGRGGRGGNNASLNPGANDFQPGNKRPRGDSEAGGGAGAKRARGGGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXB9</accession>
    <name>E3QXB9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycosyltransferase family 69 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_10651</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697394">
        <property type="protein sequence ID" value="EFQ35507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099527.1">
        <property type="nucleotide sequence ID" value="XM_008101336.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXB9"/>
    <dbReference type="STRING" id="645133.E3QXB9"/>
    <dbReference type="GeneID" id="24416016"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10651"/>
    <dbReference type="eggNOG" id="ENOG502RYQA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022271_1_0_1"/>
    <dbReference type="OrthoDB" id="262547at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021047">
        <property type="entry name" value="Mannosyltransferase_CMT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34144">
        <property type="entry name" value="CHROMOSOME 8, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34144:SF8">
        <property type="entry name" value="GLYCOSYLTRANSFERASE FAMILY 69 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11735">
        <property type="entry name" value="CAP59_mtransfer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ35507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="531" mass="61192" checksum="077CB1FA49B3B4E3" modified="2011-01-11" version="1">MPKSPENVYTEDRPSSSVEDFDLDDEHKTLLLPGPPSSSHNPRQGTVLAWLRGRQRSLLRRFRRQPRSLPRLLLRYAFLFVLFVLTATPILFPSYTRHPKHYKDLRNRCLVSDSLPGCANLRNEKVFIAVSLFDPEGKIAGGEWAKNVLDLVHMIGENNAFLSIYENDSGDLGTAALEEFKKNVPCKHKIVSDGHVDYSAFPHVTMPDGSQRLKRLAYLSEMRNRALYPLDQHDPDAGDVKYDRILFLNDALFAPIDAVHLLFNTNTGQDGRAHYLSACSIDYDWNPFLEYDLYAQRDAEGFSNGIPIFPYFTAAGKAISRKAMVSQTDAVPVKSCWGGMVAMQAKWVQNMDRKLPTKDWQAVAHHVINPDHPHNVTAPVRFRYEPELYFDACECCLFLADVTTVADKAGEPDTGVFVNPYVRVAYRKRTQRLERLIRRWERLMDLPQGIITYFSRFPTPNPHREVVEGQRFQEEIYQRREGWKMVERTGRNGMFCGVREMQLVKEGPRNGRNWENHYGIPWDEQTLHFPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QY29</accession>
    <name>E3QY29_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6590 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_10922</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697399">
        <property type="protein sequence ID" value="EFQ35767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099787.1">
        <property type="nucleotide sequence ID" value="XM_008101596.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QY29"/>
    <dbReference type="STRING" id="645133.E3QY29"/>
    <dbReference type="GeneID" id="24416287"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10922"/>
    <dbReference type="eggNOG" id="ENOG502RP3T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_667327_0_0_1"/>
    <dbReference type="OrthoDB" id="5224381at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046497">
        <property type="entry name" value="DUF6590"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20233">
        <property type="entry name" value="DUF6590"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6590" evidence="2">
        <location>
            <begin position="56"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ35767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="369" mass="41811" checksum="4BE04E11D4F67150" modified="2011-01-11" version="1">MVIGNRDFSTFRSKSTKSTKSDSGNGDDASIGTHDSSYEHPLARKGYDIGPASRCEVGDVFEFLWADSHEFEWEWKCLGYTRFIVLRHSDTFPHHCVCVPISTPTKNDFQKPGIDSSQQGYVFDENDRTPPFDRLPFSPVGMQLRPGKFRVKENSRANYADVLEIDHDAQVMVIGDVTRYFDRVRRNVNKAVMRHVLKKALEQYREGKLVDKKGAMLEASVVNGGSQDDDEPEGESDPDHPDVFLMPDETASVIEKRQPESLISAEMPPPPPPAPPLPPMDSPMPIQQPSPPRDDASSIRSYASRERRHSRREVPPLRGEDLPRKMSDQHVDGASRPYRQRIDLPRSRSHRHSEHETGSMYDVATAKMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYE4</accession>
    <name>E3QYE4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Suppressor protein SRP40</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11073</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697402">
        <property type="protein sequence ID" value="EFQ35882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099902.1">
        <property type="nucleotide sequence ID" value="XM_008101711.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYE4"/>
    <dbReference type="STRING" id="645133.E3QYE4"/>
    <dbReference type="GeneID" id="24416438"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11073"/>
    <dbReference type="eggNOG" id="ENOG502SKB6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024590_0_0_1"/>
    <dbReference type="OrthoDB" id="3595585at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="431"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="512"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="353"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="513"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="529"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="568"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="591" mass="65432" checksum="1AC6B67200F238E4" modified="2011-01-11" version="1">MTSSVAPTTHDPAGPSSDTSSAYTRLHITPLDQDLLKIVVPSSALPNARNISFHTIETFPEKRYGFVDLPETDAEKLKKRLNGAVLKGVKMRIEKARPLEEYTPVPEDEETGKKRKKKSRDKEERKRQKRDDNVVEGVQLHDRKVKRGWTVPEEAKIREKKSKKDKEKKDKKDKTKKREERSKYTEKEECLLKTKLPAKQLPATTEAEDEPERKKRKKRSKEVIIHEFEKTTKFPTFLKAAKPAPVESLTTEYVEGKGWVDAQGNVIEPPKTRRTATAPVPESKAPKASKKAKAPPPPPPPQDEDDTSSSGTSSDDDTSSDEGSDNEPEQVKASPVTPAKQTPRPPRTEDDTTSSSGSSPADTSSEDGSDDEEMTDAAKPSEPSVFETPLPAIRAADASRPISAGSNVSLTIKIPPPSTPSQVHPLEALYKRPKQGDDGNPQAAKKPEPFSFFSGGANNVDLEDEGDVAAAGQLPMTPFTAEEFEWRNVRSAAPTPDTAHPNHMKPFWAIGAEGDDEEDDEETREEIEATLNAERNAEAESGGAAAGPGGDFQKWFWDNRKNLNQSWMKRRKTAAKERRHRDNKSRASKAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYU4</accession>
    <name>E3QYU4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_11176</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697407">
        <property type="protein sequence ID" value="EFQ36032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100052.1">
        <property type="nucleotide sequence ID" value="XM_008101861.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYU4"/>
    <dbReference type="GeneID" id="24416541"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11176"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_27_0_1"/>
    <dbReference type="OrthoDB" id="440755at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17476">
        <property type="entry name" value="MFS_Amf1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718:SF9">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="76"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="144"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="273"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="304"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="346"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="383"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <begin position="410"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="437"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="532"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="78"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
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            <begin position="37"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="48"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ36032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="589" mass="63293" checksum="705CF60C15B1F606" modified="2011-01-11" version="1">MGRNSFDRAIDLNVPISEEKDVEVVFTHNIGFNELDSEKGFQTSDPVSSNSDNSDYGSSSVSSGPEKPVMSKARSIALVTTVSGASFMNTLSVQAVVIILPTIGRDIGIPESRLQWIVSAYSLAFGCFLLLWGRIADIYDKRMIFIAGTAWLAIMTLANPFIPNEIAFNVFRGLQGLGAAANVPTAIGILGTTFPPGKTKTYAFVAYGAGVPLGSVFGTLLSGFIAQYANWKCVFGVMAFLAALVAIAGFFFIPPAVPTPKEKSASVSAKKSVDWIGGGLITIGLLALMLALTEGNVVGWTTPWITILIVVSFIIISLFWFWQRYLEFQTDRLPLMKTSIFHSGKFCAALAIMGLFFASFNNFLIFATYFYQDYQAKSILTTTLYFLPTGIGGILVAWAAALLISRVPTYILLVCGQVSVSIACLLFATPIPTDTSYFAYGLPAMVLSVIGADMAWPTLILFVSKALPQEDQALGGALVNSVGQVGRSIGLAISTAVQTAIMAKARGVSVEKAGPVEEWDQPSLDGLRAANWMNFALGITSLIIVVLFFRSSEIVGREDPVPNKDSADDGAVTTTIELDLEKNEKCEKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYW8</accession>
    <name>E3QYW8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">SET domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_11200</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
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            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11200"/>
    <dbReference type="eggNOG" id="KOG1082">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="308383at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042054">
        <property type="term" value="F:histone methyltransferase activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19473">
        <property type="entry name" value="SET_SUV39H_DIM5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="H3K9_Histone-Lys_N-MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003616">
        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
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        <property type="entry name" value="Pre-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
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        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46223:SF3">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SET-23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46223">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05033">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00468">
        <property type="entry name" value="PreSET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50868">
        <property type="entry name" value="POST_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50867">
        <property type="entry name" value="PRE_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Pre-SET" evidence="10">
        <location>
            <begin position="86"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="9">
        <location>
            <begin position="169"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Post-SET" evidence="11">
        <location>
            <begin position="322"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ36056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="338" mass="38622" checksum="053A36E5817480C5" modified="2011-01-11" version="1">MEAATERHFFHHGASEPTGAKTSARALEKEKEHCHWCQIRSFPTNKQYPITIVNEVDNATIPSTFRFLQNSRLGAGVQAAEDNFRTGCECADVEECQYMGCLCLQEQEDDPDDEGHTRRKVYMYHMHGAKAGLLRSKFLNSKRPIYECHDGCACADNCPNRVVERGRKVPLQIFRTEKTGWGVRSLVDIKKGQFVDKYIGEIITPQEAQRRRAASSIAKRKDVYLFALDKFTDPDSPDVRLRGHPLEIDGEFMSGPTRFINHSCDPNLRIFARVGDHADKHIHDIAMFALRDIPKGEELTFDYVDGVSEEDDDAKNKSKQDDMVRCLCNSKNCRKFLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZ74</accession>
    <name>E3QZ74_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_11306</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697411">
        <property type="protein sequence ID" value="EFQ36162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100182.1">
        <property type="nucleotide sequence ID" value="XM_008101991.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZ74"/>
    <dbReference type="GeneID" id="24416671"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11306"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_1_1"/>
    <dbReference type="OrthoDB" id="2985014at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000188">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF9">
        <property type="entry name" value="MAJOR FACILITATOR-TYPE TRANSPORTER HXNP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="265"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="300"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="355"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="422"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="35"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ36162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="481" mass="53562" checksum="4539FAD302B07DA3" modified="2011-01-11" version="1">MGSKPSDERAVDDQESGNQIMINDATEKAYVRKMDMWLLPFLSLMYFFNASNLGNAETDGMSKDLGFVGEQYSLLILLFYIPNGLFDLPLNLLTKRYSGRIVLPGLMVGWGAMALLQAACKNFGGMLAIRLILGAFEAGFFAGAVFYLTLFYTRGELGFRIALFFGSAVLASAFSGLISFGVFRIQHPHVQGWMWLFLIEGGLTVIFGIVAFWWLPANSQSAWFLTQAEREVASLRSLRDGTRNLGEEFSLKQCFQTWKDWKFPIWCIISFTYPVAFSTTANFLPLVIGLLGYNKVTTNLLTVPPNVTGFLVLLAVTYSSDKNRERTFHIIGSLTTSLIGLVVLAVIDARAHVGVAYFATFLLTAGAYIPSCLVHSWHNNNNLSENSRAATTGLLVGLGNLGGILSAGTFRTTYAPRYAPTLLATAGCNITCIIFTLWLGIWMRIENSRRNKDQRVSLRAEDVETRDLSEGEKDQRWRFFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZX7</accession>
    <name>E3QZX7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="1">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_11543</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C19 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="1"/>
    <dbReference type="EMBL" id="GG697423">
        <property type="protein sequence ID" value="EFQ36415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100435.1">
        <property type="nucleotide sequence ID" value="XM_008102244.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZX7"/>
    <dbReference type="STRING" id="645133.E3QZX7"/>
    <dbReference type="GeneID" id="24416907"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11543"/>
    <dbReference type="eggNOG" id="KOG1868">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018461_0_0_1"/>
    <dbReference type="OrthoDB" id="2248014at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02662">
        <property type="entry name" value="Peptidase_C19F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF904">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="5">
        <location>
            <begin position="46"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="210"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="447"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="315"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="217"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="447"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="463"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="495"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="540"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ36415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="635" mass="70372" checksum="C6375A10739F002D" modified="2011-01-11" version="1">MPDKNITTISYAAGASLAAIALVYVFAPTFTIDESSTSSSRRKGVVGLRNAANDCFINSTLQALAGLGELRVYLIRETHRRNIDDEGVYSQLVQPPGKTYPDWKIEGMQRGLVTQGLKDMLDSLNERPIYKKSISAIEFVKVLETAFRQRISRQQQDAQEFLQIVAERLKEEYHAGERARAHAKLAALRATSAGSNLNGDTVQQKLEDLDKADSQGGEESSSALPTSTQPQLEVDGVRQPLQDDEGFPMEGKYESQSECQTCGYKTKPREESFYMLTLNVPQVSSTTLSSCFDEIFKTEIIDDFKCEKCRLIQAEESLKQDLAKAKGESEKAALEEAVRKLRHAIDFDPEHVPEDVLLPNISEAPKRKIARSTRLTSFPRILAVHLSRSIYDQTSTKNSAKVAFPERLPLGGLRDRRNYKLLGLVTHKGSHHSGHYESFRRQNTYAPYSNQNTFQPSGIYSKTTSPAATPQPSTPQLDAIARGVSPALSTPDLLTPTSETNSSTPSVSSLDASSSRDYAQKRISPTSAPRDKQREPDSASIRSVRSFTASARSTVSKISHKVNGNSTPGGSPPPGPTPMAVAPRPPAHRSRKKQPVDRWWRISDEKVREAKTSEVLDLRREVYLLFYELERGGSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZY7</accession>
    <name>E3QZY7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_11553</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="GeneID" id="24416917"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11553"/>
    <dbReference type="eggNOG" id="ENOG502S8JK">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="OrthoDB" id="42525at2759"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009784">
        <property type="entry name" value="DUF1349"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35332">
        <property type="entry name" value="REGULATION OF ENOLASE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35332:SF2">
        <property type="entry name" value="REGULATION OF ENOLASE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DUF1349"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ36425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="210" mass="22971" checksum="A4A31AEE2B84240E" modified="2011-01-11" version="1">MTTDTKKTPFTIEADPGTDIWRKPGHNAWNIPTAHTSSGPLKDFLSVRATFAADWTSPYDQSGVLLVPRRGSEAAAPGSKWVKTGVELYDGRPHLSTVTCDRYADWGLYPLTTTTAAAPSGAPSAVESVTIEVFRDGGAGGKNAWVHRLVLDEDGSVKERVPLRKICWIFADEDEGDWVLDVGPLAARPDKTAKDALKVEFSEFKVQWIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0M9</accession>
    <name>E3R0M9_COLGM</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
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        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EFQ36667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100687.1">
        <property type="nucleotide sequence ID" value="XM_008102496.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0M9"/>
    <dbReference type="GeneID" id="24417176"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11813"/>
    <dbReference type="HOGENOM" id="CLU_2454608_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ36667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="89" mass="10079" checksum="E02C3D4EEE5B8ED7" modified="2011-01-11" version="1">MCYYMRFICLTKDTFTIMLCGQPDDACKMRYGILPTPMIESGKAGNGDIRYGISHPIARVVYGMHLDKNKGYTTNLIDCLMKNMDVVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0Z1</accession>
    <name>E3R0Z1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11927</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697533">
        <property type="protein sequence ID" value="EFQ36779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100799.1">
        <property type="nucleotide sequence ID" value="XM_008102608.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0Z1"/>
    <dbReference type="STRING" id="645133.E3R0Z1"/>
    <dbReference type="GeneID" id="24417290"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11927"/>
    <dbReference type="eggNOG" id="ENOG502T52H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2096711_0_0_1"/>
    <dbReference type="OrthoDB" id="3584383at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
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        <location>
            <begin position="24"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="116" mass="12462" checksum="9F21196CAD25CF70" modified="2011-01-11" version="1">MLKHSILFSAIAGAAVIAGPVMALAMPSVGESVKAPEDVQRRVETSVDMEDACQREYGSDWEAILNGSGCNDWACVNTTSRQQLGLNVNLYCYETLGVTSSASCSSGAWSWRCESY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0Z2</accession>
    <name>E3R0Z2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11928</name>
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    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
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        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697533">
        <property type="protein sequence ID" value="EFQ36780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100800.1">
        <property type="nucleotide sequence ID" value="XM_008102609.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0Z2"/>
    <dbReference type="STRING" id="645133.E3R0Z2"/>
    <dbReference type="GeneID" id="24417291"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11928"/>
    <dbReference type="HOGENOM" id="CLU_2158187_0_0_1"/>
    <dbReference type="OrthoDB" id="5238639at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003181009" description="Secreted protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="111" mass="11802" checksum="9FE70E990BE8EDAE" modified="2011-01-11" version="1">MFANRPPVLGVAFSCLAFGVFGSPTPGRGSDSGSLQARAWLGGVDVNLACQIQNGDGWTSQKNDNGCDGWVCIMDGKTASVNMDVACVTQYYLNQAYAKCKGGVYDWACYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q1Z4</accession>
    <name>E3Q1Z4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">UbiA prenyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_00239</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite biosynthesis; terpenoid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the UbiA prenyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089115.1">
        <property type="nucleotide sequence ID" value="XM_008090924.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q1Z4"/>
    <dbReference type="STRING" id="645133.E3Q1Z4"/>
    <dbReference type="GeneID" id="24405604"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00239"/>
    <dbReference type="eggNOG" id="KOG1381">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075330_0_0_1"/>
    <dbReference type="OrthoDB" id="18170at2759"/>
    <dbReference type="UniPathway" id="UPA00213"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd13959">
        <property type="entry name" value="PT_UbiA_COQ2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.357.140:FF:000008">
        <property type="entry name" value="4-hydroxybenzoate octaprenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1780">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039653">
        <property type="entry name" value="Prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030470">
        <property type="entry name" value="UbiA_prenylTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11048:SF28">
        <property type="entry name" value="4-HYDROXYBENZOATE POLYPRENYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11048">
        <property type="entry name" value="PRENYLTRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00943">
        <property type="entry name" value="UBIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="124"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="158"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="218"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="261"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="288"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="320"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ25095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="350" mass="39615" checksum="84BD73B1217DF8FB" modified="2011-01-11" version="1">MLYKSISHAIELYRLEQSAKQCKEIYSGKPKPEKVTLLWHLVTLSRFNKYNPLFTTFAGVWSVLLAGASELVDPNTTIQPAFIFRQAALCFLAAYLFCGAGMVWNDWVDRDIDAKVTRTKDRPLASGTVTTVDAMLWMALQLLMSLAVVHNMLDGKDVFRHMFPVVIASIIYPYGKRPMALKLRIYPQYILGFTIAWPAVLGRSAIHGRYESIGDSIGYCLPLCCMVFFWIIYLNTAYSYQDVIDDQKINVNSFYTVAGRHFHRFLLVLISPILMCMPLYLLRFGSLWLWFSWMGVWTASFAAQLVHFDPDRPASGGGVHRSNFVLGVWTIAACGVQVLLSEKKALGIHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q223</accession>
    <name>E3Q223_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_00268</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089144.1">
        <property type="nucleotide sequence ID" value="XM_008090953.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3Q223"/>
    <dbReference type="GeneID" id="24405633"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00268"/>
    <dbReference type="eggNOG" id="KOG1910">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000592_0_0_1"/>
    <dbReference type="OrthoDB" id="1562405at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019441">
        <property type="entry name" value="FMP27/BLTP2/Hobbit_GFWDK_RBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019415">
        <property type="entry name" value="FMP27_SW_RBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019449">
        <property type="entry name" value="FMP27_WPPW_RBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045167">
        <property type="entry name" value="Hobbit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15678">
        <property type="entry name" value="ANTIGEN MLAA-22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15678:SF6">
        <property type="entry name" value="BRIDGE-LIKE LIPID TRANSFER PROTEIN FAMILY MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10344">
        <property type="entry name" value="Hobbit"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01214">
        <property type="entry name" value="Fmp27_GFWDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01215">
        <property type="entry name" value="Fmp27_SW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01216">
        <property type="entry name" value="Fmp27_WPPW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="FMP27 SW motif-containing RBG unit" evidence="5">
        <location>
            <begin position="1147"/>
            <end position="1249"/>
        </location>
    </feature>
    <feature type="domain" description="FMP27/BLTP2/Hobbit GFWDK motif-containing RBG unit" evidence="4">
        <location>
            <begin position="1267"/>
            <end position="1427"/>
        </location>
    </feature>
    <feature type="domain" description="FMP27 WPPW motif-containing RBG unit" evidence="6">
        <location>
            <begin position="1671"/>
            <end position="2192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="94"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="708"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="834"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1072"/>
            <end position="1141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1910"/>
            <end position="1938"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2010"/>
            <end position="2037"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2517"/>
            <end position="2666"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2765"/>
            <end position="2979"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1841"/>
            <end position="1868"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="100"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="115"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1072"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1087"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1098"/>
            <end position="1110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1111"/>
            <end position="1130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1920"/>
            <end position="1932"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2566"/>
            <end position="2587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2627"/>
            <end position="2636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2642"/>
            <end position="2666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2765"/>
            <end position="2779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2785"/>
            <end position="2797"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2814"/>
            <end position="2839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2840"/>
            <end position="2849"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2931"/>
            <end position="2948"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ25124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="2979" mass="335862" checksum="2BE79887B77BE4ED" modified="2011-01-11" version="1">MALLSPTFIFGVVVLLYLSSFILFAVVRILTGISIQRIGYFSLRRLAYTPRDGCKIEVRGLGLNIHRPTFAQPTWLSVVISELTVTVDIGELGGKKSEDSSTDSDSTDAEETETETQASEQPKVPLLRRNGGPPPRSQAWKHLMKLKDRMKRAHRKLNWLRMVDVVASNSTIKVVDVGDVQFGSLTVAVDTRRKMVDRARFFFQSRTDRNKQKQRQAEWIMTLRSVLFTPQGKESLEILDNATLNIHGFLYEALDGLRDAAIALKLGRVHIPYDDVRVCADRLKQCKMAARSSTLLDEPADVFIDKVIHEVAQPGSTDQELIQTVSDSKEFISSILRGVKEVQFAVSFIGMTKKVESVKPSAKPVMLNASMKEVGIDLHRLDPKSPSHRMYFPSKDIAHEALAAALSISVGVDDGDGKPERLIYIPMATTTVKTTLPSKTVEMTQDVGAEERNANILFANSVVTSPSVDLDPRHLPLIVAMLKPKSSKRPRINHQPRHMLISRLLPKANIKFTMHEPVLRVTLPAVDQHAASDDFDLIISSISSVSLDMESFHSSVEDLHYSLASTMRVQSHELYYQTSSSNRFDLIKTESFELKVQLSATPDVHVVASGNLQTSSIKMVRPEITDGLRQIVRQLRMNAEPEKRPNRHTSAKQQNFLRAMPYWLLQFQLQASDFSIEIAGIDEDISDDTRGVSLQLDEFSAEYRAQRLDGLQRRPSRRRANSRTVAPDSDLLRSPISPPPRKKQQAHGDGRRVAFHVRGLEAYIVESEDRVELEPFVNMPRFEVAFQALSDQQGPVFHIHAGIRTVLLQYSLFRHYSVGVAIMILRKAFMRSSQDISSPPMSPTSPRKETSDLLSPPMSPESPFIDMSEYSTVTPELIAIDLKAALVQVKAELPNDPQLMLQVYGVEAGRHRWSAPYLMSKLVRVYVKPPRMRTTWARMISIKGGRVDYRKSRRKLPDGGYHEDKMIDVNSDAIRFAVPHEVQVNKISDNVINTLKSVKQLHHRFKTGTNEYILDKAPGDPKNVSKVSVRTHSLLFELEDGAFEWKLGMIYRAGRVEQMQRLAREEAFEVKKKKVRDEESRKESGKLRARSLFHRGRQQSGASWVRSQSADGRRPRSDERLRGRAPRYDPDGGGLGLTGSASVAEQEARARLDAYNAQSWKKRIDRFYVMARNGMKEIRGLFWGPDQLPDDLEDTENILEVPQRPALMSALITDLQFVIDKPTFAMKDLPDFIHSVGKGMPKDMKYGLLVPMHVSIDLGEARISLRDYPLPLIHIPSLKAGQSTRLPAMSLKTNFVIAEEFRGMESTRRIKVNIIPPRNHEAGGSDEGGFAIDVRRTIGPVKSYSNMRVEINTALPTRITWGPAYQPAIQDMMMVIESFTKPQVDLSERVGFWDKIRLNFHSRIHVAWRGDGDMHLALKGTRDPYCVTGNGAGFLMCWRNNVKWNINADDDPKRFMTVDSGEYVLAIPDYSHQVREAARRTGEDESLMGEDNYKSGASFKKVVMKLSGKVQWMTGLVFERAIQDGQRSFEFRPHYDVVLRAPHHVKPEDQPYDAFRGFRSQHIHLSIAVRAPVDRDWMADNVESSRSYNTVHCTPRFFTHFFAWWSLFGGAMALPIRQGSLWPGRERNSKKFGKHLSTIKYNLLLAPLFLSHIYKHKDAEDASDSGVSATGLKVRFDSFMLDLHQRREEFNTRDRGRKTKGKTSGIKLHAAQLDLAAADVRAVSASIRGTTTEAIKKGTMANLVSNQQEDGADLSRFTIPDNDLSWIDMDDFVELDWILPMEPNPDTKILPLAFAPRLTYFRQTDIGGVIAGDPDRRSPFGDEPTHFCIMSHDDDPRRVQAQLIQERLEQLEVQIENYGRSLGDAELKVVRDDSKDPKLVAAFESLQQQGAILQRKKAYLQNMLRQMNNKSPIDGSSTFKRRENGGGGKFEESVDLEQDDSLTIPSGAEFESDFNNRFVIHNLHFKWNNTLRNIVLRYIHQVSQRRGFVYYLSRPAVKFILDIVEEQYKAKQNPKPASKNRTPTGGATAGTSPDLDAAEREFKQDIEDRIKDILKDGKKYVDAGGEDDDDVPNLPIEDLSSGISDEFTPQNSYHVRLIAPQIQLQSDKNKKNVVILTSKGMELKVVEVMDKKRLADVVSGLVQRRFLVNMDSTQFFVTHQSYFSEIVTTYAGSRYGTPATSSWPPWVPMEVMFDFETDPFGFNRVVQKTSAMLRYEKYNTLRLKYNDDVNTDGAGDSSQPSNERKMDNLWVEFPHARALCNSGDYYAMYVIVLDLLMYNEPLEKTRSERLEKIMLASDFSDLSGTPEMVEKLQERIRQLQDIKSHFQIYSKYMDEQGWEDRLLLERDLAACEDELFFMMKAITSSQRRYETNSDSNALLKWSIIARDTVWHMLRDNKEPLVELQLKDVRYDRTDNADGSHINLIRVGKVFGLNLLPDAMYPEIIAPYVDGDKGAADLGSQEMIRVYWYMLEAIAGIPVMDHFEVNLFPMKIQLEREVGKRIFEYIFPGIDGENKAKNDSPFMLKHIPTEDDEEDDDSLSGSGRLTTSDKDGFNTRPGSLELRLHPTLNSDSPTKSISSKKSLTVNTGEGQGHTFRLFRSVGTGKTMSKKPSYESLKSTKEPRPGIGRTSTGFSSKEGTAAGDGKKSRFGLRKESKTEEAKPSDDLTKMMSRASNYMTFAHIKMPSVVLCLSYKGKDNRNVEDVHDFVFRMPAVEWRNKTWSNLDLALALKKAVIKALISHTGAIIGNKFKYRPSGAQTSKLRELATGSSLTAPAPSSSSQHDAESINNSDDSSSLFGNSPVDYSRSPPRSYHGSSASSIPIPRSTSRSSSIASSRSQQTGASSNQQPNVPSFLMMTPPTPLDSRAPTQSVGFELLRPTSRGSLAPFDQAGGGTMRSLSRSGTSVEPGDRRRAAGSGFLRDKLNQLTHRKRDAAQKEDSQKQENKREETPEGEEDPNNADADSPRGSKRFSGVSSRVKTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q256</accession>
    <name>E3Q256_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Autophagy protein 16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_00301</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATG16 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089177.1">
        <property type="nucleotide sequence ID" value="XM_008090986.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q256"/>
    <dbReference type="STRING" id="645133.E3Q256"/>
    <dbReference type="GeneID" id="24405666"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00301"/>
    <dbReference type="eggNOG" id="ENOG502S5CU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082752_1_0_1"/>
    <dbReference type="OrthoDB" id="8949486at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22887">
        <property type="entry name" value="Atg16_CCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013923">
        <property type="entry name" value="Autophagy-rel_prot_16_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08614">
        <property type="entry name" value="ATG16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Autophagy-related protein 16" evidence="4">
        <location>
            <begin position="9"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="48"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="84"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="72"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ25157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="206" mass="23383" checksum="20E98C36E2371CD3" modified="2011-01-11" version="1">MPVPDWRSEYLASIREQEKNNPVNLEIVQLCSHLSDRVAALEAEKEVLRSKTAAARPDKPTSATSEKPSVRDTAPADPSTDAAVAQLQLQLAEALRSNGTLRDRAKAAEDEVQVLRAKGKEDARKLRGLTAENAALTTKLRDREHELREKRKLVENVQDEMITMNLQMTMAEQERDKVRKENKELVDRWMKRMAQEAEAMNLANER</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2A5</accession>
    <name>E3Q2A5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00350</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089226.1">
        <property type="nucleotide sequence ID" value="XM_008091035.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2A5"/>
    <dbReference type="STRING" id="645133.E3Q2A5"/>
    <dbReference type="GeneID" id="24405715"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00350"/>
    <dbReference type="HOGENOM" id="CLU_1547432_0_0_1"/>
    <dbReference type="OrthoDB" id="5087969at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="173" mass="19119" checksum="3045BF039E45EBEB" modified="2011-01-11" version="1">MATRSTRWVEFGEKVNQVTCTDSVATCTRTKYVYKGCLLPADSIMVANPKDIISQASPGSNKLRFTLASMLFQMKLSIWDSVNDEVISLINMPMSLTQEAVESMEHVAAIGEEPAKEGKKELILTILSVMFLVIAFAGETLDEANLSKIGTIFKKKADVIQNIIHKHSNQSVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2F5</accession>
    <name>E3Q2F5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_00400</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the NDUFAF3 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089276.1">
        <property type="nucleotide sequence ID" value="XM_008091085.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2F5"/>
    <dbReference type="STRING" id="645133.E3Q2F5"/>
    <dbReference type="GeneID" id="24405765"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00400"/>
    <dbReference type="eggNOG" id="KOG3363">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074390_0_1_1"/>
    <dbReference type="OrthoDB" id="20681at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05125">
        <property type="entry name" value="Mth938_2P1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1230.10:FF:000005">
        <property type="entry name" value="NADH dehydrogenase [ubiquinone]alpha subcomplex assembly factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1230.10">
        <property type="entry name" value="MTH938-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036748">
        <property type="entry name" value="MTH938-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034095">
        <property type="entry name" value="NDUF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007523">
        <property type="entry name" value="NDUFAF3/AAMDC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21192:SF2">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21192">
        <property type="entry name" value="NUCLEAR PROTEIN E3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04430">
        <property type="entry name" value="DUF498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64076">
        <property type="entry name" value="MTH938-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ25256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="221" mass="23456" checksum="155DFB806765632B" modified="2011-01-11" version="1">MHSSTSARVLRAFARAQLSLSRSVPRAYSAAPLQTSTAPAQLGRLGSQFHTCPIRSREKPKDYQGATDFGEMDVLGNTPIPSTSIDACVPDGFHLNSGVKVMDGDAALLVGGEAFAWRPWEAKGSKKLINAKGQFELPAEAFGLLGLVWPRPDLLIIGVGPKIVPLSPATKKHLSSLGIRVEVLDTRNAASQFNLLATERGVDDVAGAMIPIGWVDGKGAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2Q4</accession>
    <name>E3Q2Q4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Catalase</fullName>
            <ecNumber evidence="13">1.11.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">GLRG_00027</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 14">Catalyzes the degradation of hydrogen peroxide (H(2)O(2)) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>2 H2O2 = O2 + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:20309"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="EC" id="1.11.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Alkaloid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the catalase family.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.6" evidence="13"/>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ24883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008088903.1">
        <property type="nucleotide sequence ID" value="XM_008090712.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2Q4"/>
    <dbReference type="STRING" id="645133.E3Q2Q4"/>
    <dbReference type="GeneID" id="24405392"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00027"/>
    <dbReference type="eggNOG" id="KOG0047">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010645_2_0_1"/>
    <dbReference type="OrthoDB" id="6880011at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009820">
        <property type="term" value="P:alkaloid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042542">
        <property type="term" value="P:response to hydrogen peroxide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08157">
        <property type="entry name" value="catalase_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.180.10:FF:000001">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.180.10">
        <property type="entry name" value="Catalase core domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018028">
        <property type="entry name" value="Catalase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024708">
        <property type="entry name" value="Catalase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024711">
        <property type="entry name" value="Catalase_clade1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011614">
        <property type="entry name" value="Catalase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002226">
        <property type="entry name" value="Catalase_haem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010582">
        <property type="entry name" value="Catalase_immune_responsive"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020835">
        <property type="entry name" value="Catalase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11465">
        <property type="entry name" value="CATALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11465:SF9">
        <property type="entry name" value="CATALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00199">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06628">
        <property type="entry name" value="Catalase-rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038928">
        <property type="entry name" value="Catalase_clade1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00067">
        <property type="entry name" value="CATALASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01060">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56634">
        <property type="entry name" value="Heme-dependent catalase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00437">
        <property type="entry name" value="CATALASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00438">
        <property type="entry name" value="CATALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51402">
        <property type="entry name" value="CATALASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0017">Alkaloid metabolism</keyword>
    <keyword evidence="5 12 13" id="KW-0349">Heme</keyword>
    <keyword evidence="9 13" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="8 12 13" id="KW-0408">Iron</keyword>
    <keyword evidence="6 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 13" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catalase core" evidence="16">
        <location>
            <begin position="21"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="12">
        <location>
            <position position="351"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR038928-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR038928-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM01060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EFQ24883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="507" mass="57569" checksum="61620B5764E2BBC6" modified="2011-01-11" version="1">MGSDDEKPPSTYRYDEKPTYTTSNGAPVENPQAWQRIGPQGPLLLQDFHLIDLLAHFDRERIPERVVHAKGAGAYGEFEVTHDISDISSINMLNQVGKKTKALVRFSTVGGEKGSADSARDPRGFSVKFYTEEGNWDWVYNNTPIFFIRDPVKFPVFIHTQKRHPQTNLKDATMMFDYWSQNQECIHQLMHLFSDRGTPYSYRHMNGYSGHTHKWTKPDGSFVYVQIHLKTDQGNKTFTNAEAAKMASENPDWHTQDLFEAIERGEHPSWTVYVQTLTPEQAEKFKWNVFDLTKVWPQSEVPLRPFGKLTLNKNPENYFAEIEQAAFAPSHLVPGVEPTADPVLQSRLFSYPDTHRHRLGVNYQQIPVNKPLNAFNPFQRDGAMAVNGNYGANPNYASSFRPLDYKPVKAVNTPHEKWAGEVVTDLFGPVKPEDYEQALGLWRVLGRQPGQQENFVSNVSGALAGARPDVRARTYEMFARVTPELGAAIKKETEKIAAPAKDVRSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q331</accession>
    <name>E3Q331_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Pep3/Vps18/deep orange family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_00154</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Endomembrane system</location>
            <topology evidence="6">Peripheral membrane protein</topology>
            <orientation evidence="6">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS18 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089030.1">
        <property type="nucleotide sequence ID" value="XM_008090839.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q331"/>
    <dbReference type="STRING" id="645133.E3Q331"/>
    <dbReference type="GeneID" id="24405519"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00154"/>
    <dbReference type="eggNOG" id="KOG2034">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003488_0_0_1"/>
    <dbReference type="OrthoDB" id="1845386at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030897">
        <property type="term" value="C:HOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007032">
        <property type="term" value="P:endosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048284">
        <property type="term" value="P:organelle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007033">
        <property type="term" value="P:vacuole organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006904">
        <property type="term" value="P:vesicle docking involved in exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16462">
        <property type="entry name" value="RING-H2_Pep3p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000547">
        <property type="entry name" value="Clathrin_H-chain/VPS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007810">
        <property type="entry name" value="Pep3/Vps18_beta-prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058919">
        <property type="entry name" value="Pep3/Vps18_RING_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23323">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23323:SF26">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 18 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05131">
        <property type="entry name" value="Pep3_Vps18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26148">
        <property type="entry name" value="VPS18_RING_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50236">
        <property type="entry name" value="CHCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Pep3/Vps18 beta-propeller" evidence="10">
        <location>
            <begin position="24"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="619"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="domain" description="Pep3/Vps18 RING C-terminal" evidence="11">
        <location>
            <begin position="852"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="237"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="807"/>
            <end position="834"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF26148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ25010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="959" mass="107800" checksum="B9B773D390A85E91" modified="2011-01-11" version="1">MALNPSDGFAAGNGMLDLDDTALPMFVVERVQLQFSIAADFVAAQVANNVLVLALSNGRILRIDLNRPEDIDDIDLPKKPGEIGVIRRMFLDPTASHLLICTALGENYYLHSQHKHPRALARLRGVSIESVAWNPSLPTASTREILLGAADGNIYEAFIETTSEFYKKDIKLKNLHKLPDGPITGLWADTLPGRPDMRRVLIATHSRLFHLAGKVGNGHDSGGSIFTKLFESEQPTVHELSRSSGAATSALVVSPDPPDRNPYEDESHERAYAWLSAQGVFHGQLASSAEGNKIFNESNMLPRSQLGPSNASNKRNPTLDYIDAIALTQWHIVSLIGGRVVATNRLTGEVVYDQIVLEPGQKAVSLSVDLQKNTFWMFTAQEIFEVVVRDEDRNIWQIMLKLQQFDSALQHAKTPAQRETVATAYGDNLVAKRHFMEAASVYGRSNKPFEEVALTFIDNAEPDALRKYLLAKLGTLKKVAVMQRIMIASWLVEIFMARLNTLDDTIITQAELADGLNPARSREQLRAVQDEFQDFVNKYKYDLDRRTVYDVISSHGREQELLYFANAVNDYNYVLSYWVQRERWPEALTVLKKQTDPEVFYRYSTVLMTHVASDLVEILMRHSDLKPRKLIPALLEYNRNFDGSPAQNQAVRYLQYVINQLNSKDSAVHNTLVSIYAQSSKDEAGLLSYLESQGDEPNFDPDFALRLCIQHHRTLSCVHIYTSMGQYLQAVDLALSHNEVDLASVIADRPMSNPPLRKKLWLAVARKVISQSNGIKTAIDFLKRCDLLKIEDLIPFFPDFVVIDDFKEEICTALEDYSRNIDGLKKEMDESSQTATNIKVDIAALDHRYAIVEPGEKCYVCGLPLLSRQFFVFPCQHSFHSDCLGKRVLEQAGVGTSKRIRELQVQISKGLVSGAKREAMIAELDSLVASACILCSEFAIKRINEPFVTPQDNLNEWRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q486</accession>
    <name>E3Q486_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Sec61beta family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_00542</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SEC61-beta family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089418.1">
        <property type="nucleotide sequence ID" value="XM_008091227.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q486"/>
    <dbReference type="STRING" id="645133.E3Q486"/>
    <dbReference type="GeneID" id="24405907"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00542"/>
    <dbReference type="eggNOG" id="KOG3457">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_133423_0_1_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005784">
        <property type="term" value="C:Sec61 translocon complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030671">
        <property type="entry name" value="Sec61-beta/Sbh"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016482">
        <property type="entry name" value="SecG/Sec61-beta/Sbh"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13509">
        <property type="entry name" value="SEC61 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03911">
        <property type="entry name" value="Sec61_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="9"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ25398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="114" mass="11696" checksum="ED863DDC45EEE3FF" modified="2011-01-11" version="1">MSSPRSSSPVNAPGAVASGASVARPSSPTPPGGPRTAIRRRAAADQKEKIANARPNSTRAAGAGGSSSTMLRLYTDESPGLKVDPVVVLVLSLVFIFSVVALHIIAKITRKFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4C3</accession>
    <name>E3Q4C3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00579</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089455.1">
        <property type="nucleotide sequence ID" value="XM_008091264.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4C3"/>
    <dbReference type="STRING" id="645133.E3Q4C3"/>
    <dbReference type="GeneID" id="24405944"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00579"/>
    <dbReference type="eggNOG" id="KOG0581">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054822_1_0_1"/>
    <dbReference type="OrthoDB" id="4749307at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="282"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="317" mass="36366" checksum="DD6FC85557AEE84B" modified="2011-01-11" version="1">MAKDLKDLEGFCPTRLPLEWDLSDHELTDKFFADHYAAIVSNVKLHVDDMFRVGGLPLQGSVWTIYTERKNRDLEHIIRAIARPNPSDPNPWDELMVCNEKRMAVMRAVFMKIYSEQLFSMQLFGADDTQRQTLVRQDEEFIGHEAWLAVNVRMSPTILNFDWKLPGERYLPNQVEVYPEVYTKHRIEMTERESSKGSRYGMAHPGCKNPKPPTRTARVMISVVPLVQRISLVASNNSEEPLGFQKATLIAPRVVYYHGLNNDQDDAAQFKEGPPRYSTSSFLVRAVCVYSGFCVVILVIGSLIRLPYSENLRNLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4H5</accession>
    <name>E3Q4H5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_00631</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089507.1">
        <property type="nucleotide sequence ID" value="XM_008091316.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4H5"/>
    <dbReference type="STRING" id="645133.E3Q4H5"/>
    <dbReference type="GeneID" id="24405996"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00631"/>
    <dbReference type="eggNOG" id="ENOG502QQCH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020809_0_0_1"/>
    <dbReference type="OrthoDB" id="10253390at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021829">
        <property type="entry name" value="DUF3419"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47473">
        <property type="entry name" value="BTA1P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47473:SF1">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11899">
        <property type="entry name" value="DUF3419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ25487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="844" mass="95044" checksum="B9C8FEB7D74CAF82" modified="2011-01-11" version="1">MASLGGNILPLGLDLKTSFAGLSALALSGLLFASILSTKEAERNGNEAPSLLKSCLLFFYTCFIKPHSGDKKGNQQDALESFYEKQAGAYDATRKVLLQGREDMLALVAAQLKANDRPSKGGKAKRIWVDVGGGTGWNIEAMSSFVNVPEFFSSVYLVDFSPSLCEVARQRFERLGWNNVKVVCEDARKFSLEDYENDLPTNRIPPRSPVLSYLSQKRVEHGGADLVTMSYSLSMIPDYYSVVDSLTSLLSPDGVMGVVDFYVQSKTDFSFRNFTGGLVGRHVNWFLRTFWRAWFDIDRVGLEASRRDYLEYKFGTVLNINARNYTLGCIPYYVWVGCHKKPFSSTSLPHEIIEKIDALATESPYLFPANQGDALTRAVERSAPEIRSKAFMAAIQNLSANLPLPSFFYQKHHWRIYYDDQLQKHTQFNDEYIYAFTWEDSQVDERLLRLGSDDVVLAITSAGDNILSYAMQSPARIHAVDLNPTQNHLLELKVASYTALPYEDFWKLFGKGKHSEFRSLLLTKLSPHLSSRAFQYWLQNVHVFANSKGYGLYDTGGSRHAIRVFRWISRIFGCRAAVKEFLSTKTLNEQREVWLNKIRPALLSKLVCNLIVSQESFLWAALGVPKNQLAMIENDHAESEAVKGPRPMDRKVRSHAIWRYMVDTLDPVAEQTHIAVNNPYYHVCMTGDFTKRCHPDYLSEKAHAKLSRPNAFDGLRIHTDEIDEVINRIMPGTLTVAVVMDSMDWFDPGAPAAAAQITKLNRALKKGGRVLLRSSALNPWYIKVFEAHGFSPKRVGARIDGACIDRVNMYKSAFLCIKVENLPPPTPEMDCMGGSEITSLSLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4N7</accession>
    <name>E3Q4N7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_01196</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ26052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090072.1">
        <property type="nucleotide sequence ID" value="XM_008091881.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4N7"/>
    <dbReference type="STRING" id="645133.E3Q4N7"/>
    <dbReference type="GeneID" id="24406561"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01196"/>
    <dbReference type="eggNOG" id="ENOG502TACI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_301909_0_0_1"/>
    <dbReference type="OrthoDB" id="4846939at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="831"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="438"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="631"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="800"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="844"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="457"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="800"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="852"/>
            <end position="863"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ26052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="871" mass="94574" checksum="5EF20C2460A81E9F" modified="2011-01-11" version="1">MAALSSLGLNLRLADIDENLKSHSAALSWPNSSFCASAASASHDFLDDAPCFTYTEVFESGDVFQAVSPGSGVYLPLHSSSPGPLPAFAVSKCRSSKTIGIENWSLTLLQTLAIAMPSPFDFLSILSNYTKLKSHLQHLETISPSHPATVELRLLVGDLLLDRALYAGIGTETYRSNGHLSLAQLHDMHQRSLDAGLDGLDACFSLGLLPDVMDDAYLEALASKFTELALVGDMTALYNLCEPIVRSGEVEWEMNTDLLLQLLDRGRLDIYRYVLDLASRTRDRSSVQPASFLRDITHDPLHVAIRLGHVQQVDSLLQQGTSFIGVHHSDLTEGSADHVVLTPLSAAVYWRQPRIVRVILSKNIFADGMKEAVAMAVSDGDNDMMQILFSFGVMGVSGTPVPDNPFESFSELSLQVGAGEVPLAPPGTEIAVRFAGHQHPLDSDRPGPSAGIQGTNRQERDRAAEMPKEPLRDVCICSEHIEIRDVASRFAFADGVWGRGLKVFRGLMQDSPPSTLPEVVDSLVVANAIYLALFTHDETISPQFINDLDRWRSVLPASSQYLFDDVALRMWAYAPSTAAASEPDPVNVSHFQDLVQSLTRLEKSKETAPSRMFSPGSSLAACQRAFEDQETSPGISQAQAIPGRSQPCQSSYGGPPAQRDDLVWAEFLHMEQFEDMASEQTGPSLAEAGGWDDVMPTTMLLLVSVAFYVVLALILHLHSTPGKPVLDTFASTPGVYDRCCALLAAYLAMYGVSVRPPDDDANVAMPSFTPQSPAYGLDACITPSSSLSSLNTLGVRRNESLSSISSTENAGATSASSRDQHHRQQQRGERLPCFTPRCAKTFSSVSNRNKHLREGHELQRNDDDGTNGGQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4T3</accession>
    <name>E3Q4T3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Phosphatidylserine decarboxylase proenzyme 1, mitochondrial</fullName>
            <ecNumber evidence="12">4.1.1.65</ecNumber>
        </recommendedName>
        <component>
            <recommendedName>
                <fullName evidence="12">Phosphatidylserine decarboxylase 1 beta chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="12">Phosphatidylserine decarboxylase 1 alpha chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="12" type="primary">PSD1</name>
        <name evidence="14" type="ORF">GLRG_01242</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-L-serine + H(+) = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CO2</text>
            <dbReference type="Rhea" id="RHEA:20828"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="EC" id="4.1.1.65"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
        <text evidence="12">Binds 1 pyruvoyl group covalently per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.</text>
    </comment>
    <comment type="subcellular location">
        <molecule>Phosphatidylserine decarboxylase 1 alpha chain</molecule>
        <subcellularLocation>
            <location evidence="12">Mitochondrion inner membrane</location>
            <topology evidence="12">Peripheral membrane protein</topology>
            <orientation evidence="12">Intermembrane side</orientation>
        </subcellularLocation>
        <text evidence="12">Anchored to the mitochondrial inner membrane through its interaction with the integral membrane beta chain.</text>
    </comment>
    <comment type="subcellular location">
        <molecule>Phosphatidylserine decarboxylase 1 beta chain</molecule>
        <subcellularLocation>
            <location evidence="12">Mitochondrion inner membrane</location>
            <topology evidence="12">Single-pass membrane protein</topology>
            <orientation evidence="12">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="12">Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.65" evidence="12"/>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ26098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090118.1">
        <property type="nucleotide sequence ID" value="XM_008091927.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4T3"/>
    <dbReference type="STRING" id="645133.E3Q4T3"/>
    <dbReference type="GeneID" id="24406607"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01242"/>
    <dbReference type="eggNOG" id="KOG2420">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029061_1_1_1"/>
    <dbReference type="OrthoDB" id="4330at2759"/>
    <dbReference type="UniPathway" id="UPA00558">
        <property type="reaction ID" value="UER00616"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004609">
        <property type="term" value="F:phosphatidylserine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016540">
        <property type="term" value="P:protein autoprocessing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03208">
        <property type="entry name" value="PS_decarb_PSD_B_type1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003817">
        <property type="entry name" value="PS_Dcarbxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033177">
        <property type="entry name" value="PSD-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033661">
        <property type="entry name" value="PSD_type1_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00163">
        <property type="entry name" value="PS_decarb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067:SF6">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE PROENZYME, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02666">
        <property type="entry name" value="PS_Dcarbxylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2 12" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6 12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="8 12" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="10 12" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="11 12" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="12" id="KW-0865">Zymogen</keyword>
    <feature type="chain" id="PRO_5023492115" description="Phosphatidylserine decarboxylase 1 beta chain" evidence="12">
        <location>
            <begin position="1"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023492116" description="Phosphatidylserine decarboxylase 1 alpha chain" evidence="12">
        <location>
            <begin position="468"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="topological domain" description="Mitochondrial matrix" evidence="12">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="topological domain" description="Mitochondrial intermembrane" evidence="12">
        <location>
            <begin position="74"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="226"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="12">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="12">
        <location>
            <position position="340"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="12">
        <location>
            <position position="468"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity" evidence="12">
        <location>
            <position position="468"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage (non-hydrolytic); by autocatalysis" evidence="12">
        <location>
            <begin position="467"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="modified residue" description="Pyruvic acid (Ser); by autocatalysis" evidence="12">
        <location>
            <position position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ26098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="511" mass="56937" checksum="6B36EB5FF0A20088" modified="2011-01-11" version="1">MATLYARQSQLRAAKFFSIPGPFASTRFFSQQQQRPRFSSRLRHALKNSKVQWYQIPVGVGIGFLGLVQFYKVSSREREKEERGEVQDGAPPPKKRAKIRPDGPWQVQVMSTLPLKAISRLWGRFNELTIPYYLRVPGFKLYSWIFGVNLSEVAEPDLHTYPNLASFFYRELKPGARPLDPNSNALLSPSDGRVLQYGQIQGGDIEQVKGMTYSIDALLGKNTPTPSISSGWSTPQEVEAENSNSVSPSQDLVKTDEEFARVNGISYTVPSLLSGAAMSQRRGSLKDEAGEHPSASAVSEVRADLALGEKPWYDLISPDNKTALYYAVIYLAPGDYHRFHSPANWVVERRRHFAGELFSVSPYLQRTLPGLFTLNERVVLLGRWRYGFFSYVPVGATNVGSIKINFDRELRTNSLTTDTAADRAAEEAANRGEPYTGFSEATYASASPVLGGHALRRGEEMGGFQLGSTIVLVFEAPTEGKTPEDKKGWRWAVEKGQTVRMGQALGYVEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5I6</accession>
    <name>E3Q5I6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_01097</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089973.1">
        <property type="nucleotide sequence ID" value="XM_008091782.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5I6"/>
    <dbReference type="STRING" id="645133.E3Q5I6"/>
    <dbReference type="GeneID" id="24406462"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01097"/>
    <dbReference type="eggNOG" id="ENOG502RS7H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_422103_0_0_1"/>
    <dbReference type="OrthoDB" id="4850280at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ25953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="649" mass="71710" checksum="FB4F7373EF89B9F2" modified="2011-01-11" version="1">MRIAKDMWNWTMSPSLADSNASLVPPEWPSNSDIERLAGMTASRSSTTKTHLGYSPIHEDNIPEEQNASRLKSCFATLSPTSGANAANSSSDGDRNFAVTCRSQEIPDAERSCWFDLVSGGAVIAANFPVPARHDEKGLEIPMGILVRIAVIHDAIEYKGGIVMKGPTLMLVPIKRNADLSIIQWHVVSASKKRKRLTYLEGVEKCKQRALVDEVDLQSFLRCRALVGWWDHAKSRLGDEDVNFDNLRWSTAKPYEPLRIQNIAAGLQQIGVLNIECAPGCKDSGYLVKFEGPYGEMLSTARGEKAFLYDTVQQRAWLVTRDEVMLHIIRKRNSDRPFFCNGAPVKIPTIGSAMQSLLVNRKLVLVDDEDEPETLRLMAVRIFNQLETLAAMDDDRRQAPEKAFNVPDVLIGHEFMSTVNRTVGRRMKKNEIRTTSGGWARLVEDSASLVLFANGFGDLICPTADSEMLCSRWKTVPWGKDYLAATTDTLLRLYFKGNEISQEYLTSSGLCWHKHQSQIVPKPMSIGAVDRPRPVAAGGAVIFGVESVMAKLTLPTVLRTKKDAVMYSQPSFQIESRMACENSALDRVKEDSTALQQLPEKSALSIESGSTTVAQFSDSSDEGAGRLFGIPTAPISGSMEEEGLGKAWC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5K2</accession>
    <name>E3Q5K2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Developmentally Regulated MAPK Interacting protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_01113</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089989.1">
        <property type="nucleotide sequence ID" value="XM_008091798.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5K2"/>
    <dbReference type="STRING" id="645133.E3Q5K2"/>
    <dbReference type="GeneID" id="24406478"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01113"/>
    <dbReference type="eggNOG" id="ENOG502SQXC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_088315_0_0_1"/>
    <dbReference type="OrthoDB" id="5420143at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052479">
        <property type="entry name" value="GPI-anchor_Adhesion_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018466">
        <property type="entry name" value="Kre9/Knh1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35185:SF2">
        <property type="entry name" value="EXTRACELLULAR PROLINE-SERINE RICH PROTEIN (AFU_ORTHOLOGUE AFUA_8G07090)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35185">
        <property type="entry name" value="SERINE/THREONINE-RICH PROTEIN ADG2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10342">
        <property type="entry name" value="Kre9_KNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179439" evidence="2">
        <location>
            <begin position="18"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal" evidence="3">
        <location>
            <begin position="22"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ25969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="228" mass="23740" checksum="8A0871281EE9AA40" modified="2011-01-11" version="1">MRFSATALALVAPLVSAIEFTSPSINSTVTKGSSYELTWKAVDTDPSAFSIFLVNFVNWPPSYTLLAENIETSAGAVSVDVPCSASNSYGYQFNAINGTNVYVIYAQTPKFSISGADCTGPTTLPPASPSICAPPSTVTVTVSKTLSRNSTAVATGGISAAQSKITTPAAVSASSQTTSSPVFHGTCPDIIGWASDYYHPVALTKPPRHPDNAAAFALPTNAPLNRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5L3</accession>
    <name>E3Q5L3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_01124</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. Epoxide hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090000.1">
        <property type="nucleotide sequence ID" value="XM_008091809.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5L3"/>
    <dbReference type="STRING" id="645133.E3Q5L3"/>
    <dbReference type="GeneID" id="24406489"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01124"/>
    <dbReference type="eggNOG" id="KOG4178">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_7_5_1"/>
    <dbReference type="OrthoDB" id="408373at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43329">
        <property type="entry name" value="EPOXIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="37"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ25980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="352" mass="38283" checksum="016FF1A3A1132F62" modified="2011-01-11" version="1">MAVESARFPQFEYQTATLNGVTYNYIHAEPAGKVVGTIFLIHGWPDLSVGWQKQIPYLLSKGLRVIAPDMMGYGGTDAPEDVGLYTFKRASDDIAALASHLGVSRIILGGHDWGGAVVYRAALWHPELVAAFFVVSTPFAPPRITFVDQALALPTLHYQLQFRTDDIQDYIGPVNAQNATRVRQILNTLYGSVLPNGESAFNSSGDGLALDQLDGVTKDTPLMTTEEVDFYVDTYSAKPFNRTLNWYRTSELNFQDELALLPADGTYASKYTQPALYIGGSRDTALPPILSTGMDVYFDSLARGVVDGTHWAMREKPQDVNDLIGGWLAGSVLGNLTVGLNLTAGIGALSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5Z8</accession>
    <name>E3Q5Z8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_01390</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHEK2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090266.1">
        <property type="nucleotide sequence ID" value="XM_008092075.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5Z8"/>
    <dbReference type="STRING" id="645133.E3Q5Z8"/>
    <dbReference type="GeneID" id="24406755"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01390"/>
    <dbReference type="eggNOG" id="KOG0615">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_171_0_1"/>
    <dbReference type="OrthoDB" id="407410at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05117">
        <property type="entry name" value="STKc_CAMK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.200.20:FF:000132">
        <property type="entry name" value="Cell-cycle checkpoint serine-threonine kinase (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:001380">
        <property type="entry name" value="Checkpoint kinase 2-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000841">
        <property type="entry name" value="Checkpoint kinase 2-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="6">
        <location>
            <begin position="192"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="283"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="633"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="22"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="55"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ26246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="665" mass="74387" checksum="E1CA2AA2CA2C22FA" modified="2011-01-11" version="1">MAPQSEKSQLKRTRGSLPESDLDAKKPRRSERTSPEPNDKTPVSNKHQLPSPVTRDSDSDEVYKEPTATPPEGRPSQVNHREKDDTSHALNNISSPPQDTQAFSQYPQETKDALSDEVEDEVKEGVWGYLFPLDTKYGKVVVMKKRAACPLPDTVNAAKESAGKDQKGKSTLQKEEEAYERTKIKGIASGGYLIGRHPECDIVVEDPIVSNRHCLIFSENKGGDNVAIVEDLSSNGTFVNEANVGRNKRRELQEQDEIAVIDKARFIFRYPKTRQSSAFLNQYTLLEKLGKGHFAEVFLCVEKSTGQRYAVKIFTKTAGMDERSKQEGLQQEIAVLMGVSHPNVLCLKDTFNERNAVYLVLELAPEGELFNFIVMKQKLSEDETRKLFKQLFQGIKYLHDRNIVHRDIKPENILMVDRDLHVKLADFGLAKIIGEESFTTTLCGTPSYVAPEILAEGRHRKYTKAVDIWSLGVVLYICLCGFPPFSDELYSTDFPFTLSQQIKSGRFDYPSPYWDSVGDPALDLIDSMLVVDPERRYTVDQCLNHPWMTQNQPGVNDSTDGLVGGIQGLDVHRRGVTRERTLLSSMNSVQVATRPPVGDSKKPIHIYAKNTKKMVPKEVDPHGQRNVSEFVEMGGKGDQPLFGADGESIYSKDDISGGKTKGGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q610</accession>
    <name>E3Q610_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Double-strand-break repair protein rad21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_01402</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the rad21 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090278.1">
        <property type="nucleotide sequence ID" value="XM_008092087.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q610"/>
    <dbReference type="STRING" id="645133.E3Q610"/>
    <dbReference type="GeneID" id="24406767"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01402"/>
    <dbReference type="eggNOG" id="KOG1213">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015775_0_1_1"/>
    <dbReference type="OrthoDB" id="10071381at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030892">
        <property type="term" value="C:mitotic cohesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007064">
        <property type="term" value="P:mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990414">
        <property type="term" value="P:replication-born double-strand break repair via sister chromatid exchange"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21788">
        <property type="entry name" value="Rad21_Rec8_M_SpRad21p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.580:FF:000004">
        <property type="entry name" value="Double-strand-break repair protein rad21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.580">
        <property type="entry name" value="Structural maintenance of chromosome 1. Chain E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039781">
        <property type="entry name" value="Rad21/Rec8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006909">
        <property type="entry name" value="Rad21/Rec8_C_eu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006910">
        <property type="entry name" value="Rad21_Rec8_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023093">
        <property type="entry name" value="ScpA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12585:SF69">
        <property type="entry name" value="FI11703P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12585">
        <property type="entry name" value="SCC1 / RAD21 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04824">
        <property type="entry name" value="Rad21_Rec8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04825">
        <property type="entry name" value="Rad21_Rec8_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rad21/Rec8-like protein N-terminal" evidence="6">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="Rad21/Rec8-like protein C-terminal eukaryotic" evidence="5">
        <location>
            <begin position="557"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="427"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="488"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="618"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="631"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ26258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="645" mass="71241" checksum="6F7B53E620649D07" modified="2011-01-11" version="1">MFYSETLLQKSGPLARVWLSANIERKLSKTHILQSNLPDSVEAIITPGQAPMALRLSGQLLLGVVRIYNRKARYLLEDCNEASMKIKMAFRSSDNHDMAVANLYVNNREALLLPDKITPLDNLDLPPPPDAAWLLSQMDDVTATPVGRKGRVSHRDINLQEDFNNSQFLTQGDTLDDELELAPMEDLDLELDFGMDVDDRPTRMDTTIEMGRDAPLARSVEDDMFSELDIMPRGKDQPEREPSLGLALDFGDDNVRIADEEGDIQMGDDNEFQFPAGDQSVAPGFPGALDMPRGRISESPLSEIDPEFAREVEEEYSRIQHTDLYEPDEDQDRTVVRHPQRSKKRRILLPDEQTMLSSNHIKDQQANHGNILRPQSFLPRDPFVLALMEMQKSGGFVSNIMLEGRGASWAPELRGLLSLEAVSRSSELKRKRDSGIADVESENDATSKSPRLIVEEEEAFAVEAAGFGNQSVAGDGTVLEIPAEEEGIAFGGDDDNTRPVSREGSPMPGFDETTAPEVHPQDSGPVSLGTKHAVHILRDIFGPDAENDAEKRKKTAVVFQDLLPEGRTTKADATKMFFECLVLATKDAIKVEQGETLGAPIRVRAKRGLWGAWAEREAGGEIAEEEEANQPEPAVVSAPAVAVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q699</accession>
    <name>E3Q699_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Preprotein translocase subunit Sec66</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_01491</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090367.1">
        <property type="nucleotide sequence ID" value="XM_008092176.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q699"/>
    <dbReference type="STRING" id="645133.E3Q699"/>
    <dbReference type="GeneID" id="24406856"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01491"/>
    <dbReference type="eggNOG" id="KOG4699">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066294_0_0_1"/>
    <dbReference type="OrthoDB" id="73168at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031207">
        <property type="term" value="C:Sec62/Sec63 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031204">
        <property type="term" value="P:post-translational protein targeting to membrane, translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018624">
        <property type="entry name" value="Sec66"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28229">
        <property type="entry name" value="TRANSLOCATION PROTEIN SEC66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28229:SF1">
        <property type="entry name" value="TRANSLOCATION PROTEIN SEC66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09802">
        <property type="entry name" value="Sec66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ26347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="231" mass="26148" checksum="7F3F5E4B841860B6" modified="2011-01-11" version="1">MFNVDWMSLVLPFAYLTVLGGVFMTFSTIYRKRKATQSANLAPWFGPHLQRNIYLSLLHLESPEEGQEKAPKIPSTVIKAALLRRAVEDIHRIVQIRSAKQACSTLLQRGSVGDDLWQRFQRAEKEMEDELRDVVMEANALAPNWGQSIFQSANEIAANTIARNRLEEVANTVEQEKAWWEKRRATIQTEFMKELDDSEKNSTAPPSVDGDAVLVDSNTTSTPSKKKKGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6B7</accession>
    <name>E3Q6B7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Peroxisomal trans-2-enoyl-CoA reductase</fullName>
            <ecNumber evidence="13">1.3.1.38</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">GLRG_01509</name>
    </gene>
    <organism evidence="22">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Participates in chain elongation of fatty acids. Catalyzes the reduction of trans-2-enoyl-CoAs of varying chain lengths from 6:1 to 16:1, having maximum activity with 10:1 CoA. Has no 2,4-dienoyl-CoA reductase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>(2E)-decenoyl-CoA + NADPH + H(+) = decanoyl-CoA + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:44960"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:61406"/>
            <dbReference type="ChEBI" id="CHEBI:61430"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="19">
            <dbReference type="Rhea" id="RHEA:44961"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>(2E)-dodecenoyl-CoA + NADPH + H(+) = dodecanoyl-CoA + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:44964"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57330"/>
            <dbReference type="ChEBI" id="CHEBI:57375"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:44965"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>(2E)-hexenoyl-CoA + NADPH + H(+) = hexanoyl-CoA + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:44956"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:62077"/>
            <dbReference type="ChEBI" id="CHEBI:62620"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="17">
            <dbReference type="Rhea" id="RHEA:44957"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>(2E)-octenoyl-CoA + NADPH + H(+) = octanoyl-CoA + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:44952"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57386"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:62242"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="20">
            <dbReference type="Rhea" id="RHEA:44953"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>(2E)-tetradecenoyl-CoA + NADPH + H(+) = tetradecanoyl-CoA + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:44968"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57385"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:61405"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="16">
            <dbReference type="Rhea" id="RHEA:44969"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>a (2E)-enoyl-CoA + NADPH + H(+) = a 2,3-saturated acyl-CoA + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:33763"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58856"/>
            <dbReference type="ChEBI" id="CHEBI:65111"/>
            <dbReference type="EC" id="1.3.1.38"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="18">
            <dbReference type="Rhea" id="RHEA:33764"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Interacts with PEX5, probably required to target it into peroxisomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="1.3.1.38" evidence="13"/>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090385.1">
        <property type="nucleotide sequence ID" value="XM_008092194.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6B7"/>
    <dbReference type="STRING" id="645133.E3Q6B7"/>
    <dbReference type="GeneID" id="24406874"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01509"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_847382_0_0_1"/>
    <dbReference type="OrthoDB" id="414540at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019166">
        <property type="term" value="F:trans-2-enoyl-CoA reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033306">
        <property type="term" value="P:phytol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052388">
        <property type="entry name" value="Peroxisomal_t2-enoyl-CoA_red"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24317">
        <property type="entry name" value="PEROXISOMAL TRANS-2-ENOYL-COA REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24317:SF7">
        <property type="entry name" value="PEROXISOMAL TRANS-2-ENOYL-COA REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00038622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00041063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00049108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00049251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00049386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00049559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EFQ26365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="289" mass="30195" checksum="BACC81E836C78F41" modified="2011-01-11" version="1">MDSTPHFSPYRADGKLYGFVCVVTGAAHPVGRAIVEELAACDKTTSDETFHTLVANVHRDHPNTKVIPYPFNVAKEEETLVLIDEVLNAFGRLDIWVSSTGLLGPPSIAETTPADLQRCFEGHSMAPFFALKYAPPAMAKLTEKQSYPNAAPKTQKYGSIIVISSAASWGPSYTMSAYAALGVVKAGVAVLRDTGVRINCISPGQIDVGLDLNGANVKGVNSQLPTAGSQGNESAEAIIGLGRPGSPQEVARVAGFLASGFSSYITGANMVVDGGSSAMNPLTVPLGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6E9</accession>
    <name>E3Q6E9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Sterol-4-alpha-carboxylate 3-dehydrogenase ERG26, decarboxylating</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15 16">C-3 Sterol dehydrogenase ERG26</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13 14">C-4 decarboxylase ERG26</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Sterol-4-alpha-carboxylate 3-dehydrogenase erg26, decarboxylating</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">GLRG_01541</name>
    </gene>
    <organism evidence="19">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="10">Heterotetramer of ERG25, ERG26, ERG27 and ERG28. ERG28 acts as a scaffold to tether ERG27 and other 4,4-demethylation-related enzymes, forming a demethylation enzyme complex, in the endoplasmic reticulum.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the 3-beta-HSD family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090417.1">
        <property type="nucleotide sequence ID" value="XM_008092226.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6E9"/>
    <dbReference type="STRING" id="645133.E3Q6E9"/>
    <dbReference type="GeneID" id="24406906"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01541"/>
    <dbReference type="eggNOG" id="KOG1430">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_6_8_1"/>
    <dbReference type="OrthoDB" id="10058185at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000252">
        <property type="term" value="F:3-beta-hydroxysteroid dehydrogenase [NAD(P)+]/C4-decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000346">
        <property type="entry name" value="C-3 sterol dehydrogenase/C-4 decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002225">
        <property type="entry name" value="3Beta_OHSteriod_DH/Estase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050177">
        <property type="entry name" value="Lipid_A_modif_metabolic_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43245">
        <property type="entry name" value="BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43245:SF51">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY 42E, MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01073">
        <property type="entry name" value="3Beta_HSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="18" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0752">Steroid biosynthesis</keyword>
    <feature type="domain" description="3-beta hydroxysteroid dehydrogenase/isomerase" evidence="17">
        <location>
            <begin position="15"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00046995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00067470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00067985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00081267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00081397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00081452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00082106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF01073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EFQ26397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="376" mass="41190" checksum="4C767A2C81A89834" modified="2011-01-11" version="1">MSEKKSATPNLGKVLVIGGNGFLGHHVVNQLLAGDRWAVTSVDVIDLRCGHNRHPKANYHEADITDADRMKSILENTKPDIVIHTASPAAQGDGPVAKDLFRKVNIDGTASVVAACQACSVKALVYTSSASIISDNTSDLINADERWPVIRGELQTEYYSETKAAAEELVLNANRQDPYPLVTCSIRPAGIFGEGDTMVTHQMVKIYREGKTGFQLGDNDNLFDFTYVGNVAHAHLLAARMLLATAGASTAPLDHEKVDGEAFLVTNDSPIYFWDFTRAIWRAAGSDKGTSHVWTIPREIGAVLGFCSEVFCSIIGKPPTFNRQRNIYSCMTRYYNISKAKRLLGYRPIVSLDDGIKRGVQWFLDQEKAGKVGIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7E9</accession>
    <name>E3Q7E9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">WD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_02607</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090807.1">
        <property type="nucleotide sequence ID" value="XM_008092616.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7E9"/>
    <dbReference type="STRING" id="645133.E3Q7E9"/>
    <dbReference type="GeneID" id="24407972"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02607"/>
    <dbReference type="eggNOG" id="KOG0309">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001497_0_0_1"/>
    <dbReference type="OrthoDB" id="311712at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035859">
        <property type="term" value="C:Seh1-associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035591">
        <property type="term" value="F:signaling adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034198">
        <property type="term" value="P:cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00195">
        <property type="entry name" value="UBCc_UEV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049567">
        <property type="entry name" value="WDR59-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46170">
        <property type="entry name" value="GATOR COMPLEX PROTEIN WDR59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46170:SF1">
        <property type="entry name" value="GATOR COMPLEX PROTEIN WDR59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="124"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="211"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="465"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="626"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="720"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="784"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1064"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1101"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="467"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="725"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="741"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="752"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="793"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1073"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1104"/>
            <end position="1116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ26787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1135" mass="125557" checksum="09AF005379C31D7F" modified="2011-01-11" version="1">MPHFDRLDAPKKGKPIKSAFDSESFDADGTIHVAGLVGSATISPSSRDVALASPEGLSIIDLDSPYNPPRRLSSHGSPWLVTDVQWSPFAARDYWVVSTANHRALVWNLNLRDDSATGAIEHSLHGHSRAITDINWSAYHPDQLASCAVDGYVHCWDLRRPRQPVLTFCDWFAGATQVKYNRQDPHILASSHDRWLHIWDERRACEPLKSISAHTSKIYGIDWNRTRSTGIVTCSLDKHIKFWDYGSDQDVPERVICTQFPVWRARHTPFGHGLLAMPQNEPGDLYLYDQRPPPEGPGKGPTEPVAVFPGHGNHKAKEFLWRSRGGITDDGLDERDFQLVSWGEDNELRLQQVDRPILESVGFVKGMPATKNLVLTRKGAAYKTFRTVGDHIIRDRRSGTMSDPRNSAQYRQSALTMGMRSGPTTYAKLGAAWKGSSMKAKSVSKEMDRSQAHIGWMKGIMMNKRKASTDSPRRADSKDSTMFSPGYMDDDKWGDPETIQEEFLRISMQLPKVKWEHIDMDNLTLKASLNGPWGANGEPIFIKVTVDIPSNYPKFRAPTFFIEKTGFMSARTHRKIEHEIHELCQQFLERKQNCLDVAFSYLLGEIDLAASTNFFKNVKDLDDPLDGLGSESSSEDENDIPAGGSASMSQELPPHAEADSTLAPNNRPTIPPLPRFCGARFANDGRLVCFFPTKEEKARALFSTSVEPLRERAKGEPVFAGFGRLAHDSPPGKRYGQDDMSATDDQSDSDDSTGSSSSSSDSGSTSINKMSLWYQPRHRFKRTWSDNRSVRSSGGGTGVGTGTGTGSFRRRPGAKSKNVVSLHDTSDLLPAKKEFAREYAIFGDGAQVCEHNAQVAEKHGCQDLVDVWRYLSLILRRDIPLEFSNMDPHHNSILIIARDALARFRHKDSPGLQNASGKDTAVFSGRVKWGNHPLARHFISDLLEYYEKTADIQMLAMLSCIFSEAFTEDSVAYAESHMTQPDTPLPMKTPAFSLDYFPTDASLWNLDGRSQTNSAIATPGTLHTPIRYSGSQGSAEEVFWAGDPGSNSYSCGETPPNRGFKEYLGGEGDQVPPSLSTSPSGRALSRVNSGLPSSFAISLPRPFSGVATGTTTAASSPPNHGRKRPSPAETLCNDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7Y0</accession>
    <name>E3Q7Y0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_02163</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ26992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091012.1">
        <property type="nucleotide sequence ID" value="XM_008092821.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7Y0"/>
    <dbReference type="STRING" id="645133.E3Q7Y0"/>
    <dbReference type="GeneID" id="24407528"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02163"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_1_1"/>
    <dbReference type="OrthoDB" id="10254877at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050085">
        <property type="term" value="F:mannitol 2-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050664">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019594">
        <property type="term" value="P:mannitol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05352">
        <property type="entry name" value="MDH-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000090">
        <property type="entry name" value="NADP-dependent mannitol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF3">
        <property type="entry name" value="MANNITOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ26992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="266" mass="28435" checksum="B3904F3A85F45753" modified="2011-01-11" version="1">MPQGIPTASRLLDLFSLKGKVVVVTGASGPRGMGIEAARGCAEMGADLALTYSSRKEGAEKNAAELEKEYGVKVKIYKLNVSDYDNVEATTKQIISDFGKIDAFIANAGATADSGVIDGSKEAWDHVIQIDLNGTAYCAKAVGAHFRERGTGSFVITASMSGHIANYPQEQTSYNVAKAGCIHMARSLANEWRDFARVNSISPGYIDTGLSDFVAQETQELWKSMIPMGRNGDAKELKGAYVYLVSDASTYTTGADIVIDGGYTCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7Y8</accession>
    <name>E3Q7Y8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Retinol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_02171</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091020.1">
        <property type="nucleotide sequence ID" value="XM_008092829.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7Y8"/>
    <dbReference type="STRING" id="645133.E3Q7Y8"/>
    <dbReference type="GeneID" id="24407536"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02171"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_44_6_1"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF282">
        <property type="entry name" value="WW DOMAIN-CONTAINING OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ27000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="266" mass="29289" checksum="A9F3796CAF0DD86D" modified="2011-01-11" version="1" fragment="single">PAHIYLAARNEAKALAAIEDIKKAVPKAAPITFLEIDLTSFESIKRAANEFRSKSETLHILVNNAGIMAWPPSTTKEGYEIQFGTNHMGHALLTKLLLPTLQHTAQTSPDKDVRIVSLSSVGENWVPSDLYNFDDLKTDMASTGTWARYGASKVANIHHSRALAKRYPEIRCISVHPGSVNTNLTSGLEASWPLIKPILGIFAPLVLSSVADGAKNQIWASVSPDAESGVFYWPVGVKGRDSKHAKNEELSEKLWEWTEKELEAYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q876</accession>
    <name>E3Q876_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">E3 ubiquitin protein ligase</fullName>
            <ecNumber evidence="15">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">GLRG_02259</name>
    </gene>
    <organism evidence="20">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 15">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 15">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the BRE1 family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="15"/>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091108.1">
        <property type="nucleotide sequence ID" value="XM_008092917.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q876"/>
    <dbReference type="STRING" id="645133.E3Q876"/>
    <dbReference type="GeneID" id="24407624"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02259"/>
    <dbReference type="eggNOG" id="KOG0978">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019713_2_0_1"/>
    <dbReference type="OrthoDB" id="654191at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033503">
        <property type="term" value="C:HULC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16499">
        <property type="entry name" value="RING-HC_Bre1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058643">
        <property type="entry name" value="BRE1-like_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013956">
        <property type="entry name" value="E3_ubiquit_lig_Bre1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23163:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE BRE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23163">
        <property type="entry name" value="RING FINGER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08647">
        <property type="entry name" value="BRE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26095">
        <property type="entry name" value="CC_Bre1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 15" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="11 15 16" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="19" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 15" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9 15" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 14 15" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="18">
        <location>
            <begin position="654"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="136"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="256"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="383"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="441"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="535"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00059679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU365038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EFQ27088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="706" mass="80848" checksum="75F4EE0BDE4428DA" modified="2011-01-11" version="1">MEDRKRPPISTAEDLAPPSKRHQTVNGSKSKGDGGDTAEEHWIENYQKGAIYRQLQETKREKADFESRVEQLQKALVYREDHIRIIEAWWKQVLEEMEQLADPALSPLSGPSNPPYITSTHFKDNDEFQRHLDDTASDIKKRAEAVLNRIANARGEITPNIADLETRVNALLAQQKDYLVKLDRAQQENEQLSEDLNKASLRFFKAEKRMDRLKSAQVQKLEQQFIASAKPTIAGGENGSAAAEANGNAAEALIKFEEASAVVKKQKEQLESAQADIKTLQEENSALKARREGLTDEDFIRTDVFKQFKGQNEDLIKRINHLEATNKQLREEAERLQAERTAFRTKLNDEAQMITSDLERQVEERDADLTRIRAARDEWYAKANMLETREKEEKQALQHLKELTGAQEDRIASLELELQRLKPTEDQQMADPDPELESMPADELLSKYKKLQQDFESINKELPALQQAYKRSMGLAQKKVMEYTVLEERASAALAEKQKVDQKYFAVKKDADMRDRELSVLRSQNRKSSEIVTQLKEVEAQNRVLISNLEKQLSDLKQANAAMAAEHKKMESASSDAARRADSYKNQVSELTNLVKSRDAAVAAARERTTTQEAEVERLKVRADMVQKDKDEWKRKALSNSSEEEEMLRTFALCTVCRNNFKDTALKTCGHLFCHQCVDDRISNRMRKCPNCSRAFDRLDVMSVHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8M2</accession>
    <name>E3Q8M2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF2434 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_01881</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091406.1">
        <property type="nucleotide sequence ID" value="XM_008093215.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8M2"/>
    <dbReference type="STRING" id="645133.E3Q8M2"/>
    <dbReference type="GeneID" id="24407246"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01881"/>
    <dbReference type="eggNOG" id="ENOG502QWQE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033097_0_0_1"/>
    <dbReference type="OrthoDB" id="5308502at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018830">
        <property type="entry name" value="DUF2434"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10361">
        <property type="entry name" value="DUF2434"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="212"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="261"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="302"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="342"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="441"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="511"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="480"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="555"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ27386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="580" mass="64765" checksum="87006A83E01AD2B0" modified="2011-01-11" version="1">MALHARALLGFPPGANASDTVLAGVHFNRTVLSFWNYTLYTNGTLSNGSNCYVVESPYTPVGLLPNGSFVNSTWCYDPINPIGPRAGVGVGFGVVYGLALVLVLACLTKHGRSHLPVSKRFYPVGRRWQWYYAILVCVAAFISLFTNIDVDRFYVVGLPIVINSFFWYLLQQFTMALVWEAVRHWGSWSERQAIDPDPFSLREGDRRSKVEFWAPLWFYFWLWLNFFLIIPRNWGEIEKQRSPDQTASRAAPNATDARFKAATFCLVVCWLTIVASLRHSIKHYYPRNRGLLNKARGFLRYVPLRFLLIIPLAACLVAYQGIVSWNFAYSVLNAKASLAPVYAGGYGPALLILYIQIAYGFLSPNEDKELIRQRRERGAQIDREMGYVPKPAWWKRAKNDDHLVGRMSMRERIARNVRELGGGAATNRGVHQNIDAMAEEREQRERADDEIEMGPVSRGNTTATASAAPVPVRPGFDAAQGSTFASYSGKSDRRRNERAMAAAADLLFPVAGASRPDRTSELTQDGPPPSYTDVPVTRGRGGRTDGVNAPHDPSQRSNSTSTAVSITGQQPQQVKSMLDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q973</accession>
    <name>E3Q973_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sterol 3-beta-glucosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.173</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Autophagy-related protein 26</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">GLRG_01747</name>
    </gene>
    <organism evidence="19">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a sterol + UDP-alpha-D-glucose = a sterol 3-beta-D-glucoside + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22724"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15889"/>
            <dbReference type="ChEBI" id="CHEBI:37424"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.4.1.173"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:22725"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ergosterol + UDP-alpha-D-glucose = ergosteryl 3-beta-D-glucoside + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:61836"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16933"/>
            <dbReference type="ChEBI" id="CHEBI:52973"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:61837"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Preautophagosomal structure membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 28 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.173" evidence="4"/>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091272.1">
        <property type="nucleotide sequence ID" value="XM_008093081.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3Q973"/>
    <dbReference type="GeneID" id="24407112"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01747"/>
    <dbReference type="eggNOG" id="KOG1192">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000537_6_0_1"/>
    <dbReference type="OrthoDB" id="10261837at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016906">
        <property type="term" value="F:sterol 3-beta-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016125">
        <property type="term" value="P:sterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13215">
        <property type="entry name" value="PH-GRAM1_AGT26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13216">
        <property type="entry name" value="PH-GRAM2_AGT26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000303">
        <property type="entry name" value="Sterol 3-beta-glucosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000560">
        <property type="entry name" value="Sterol 3-beta-glucosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000029">
        <property type="entry name" value="Sterol 3-beta-glucosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000009">
        <property type="entry name" value="Sterol 3-beta-glucosyltransferase UGT80A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048066">
        <property type="entry name" value="ATG26_PH_GRAM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048065">
        <property type="entry name" value="ATG26_PH_GRAM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010610">
        <property type="entry name" value="EryCIII-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050426">
        <property type="entry name" value="Glycosyltransferase_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004182">
        <property type="entry name" value="GRAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050:SF25">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06722">
        <property type="entry name" value="EryCIII-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02893">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00568">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0072">Autophagy</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 18" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PH" evidence="17">
        <location>
            <begin position="324"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="36"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="88"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="502"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="595"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1416"/>
            <end position="1481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="100"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="161"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="209"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="512"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="621"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="643"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="676"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="1420"/>
            <end position="1429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EFQ27252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1481" mass="166502" checksum="C7D7E361B7D5822B" modified="2011-01-11" version="1">MATPGPAGAASVSFGADDEVKKRVGKKLVKKRFETNTPAIELPERLKEGDDSREEDLVPTQGPPMFMNMNQSIFGLIAAAGSRVDFHDRFESSDDDSGDEPDHDRQRDALDDKSRGLAHLLHRKQRRPDTHQPDLSKTTVLKKDSSSKSEKHRRKISGSKLLRSLPALPRLPRHKSKKEKSNLQSPSSDEATHPSEVRPTQPTNHIREEEGEEEEEDDDDEDGRDYRHAPVMSRMLEAKAEMSARPSFDIDRLSADQLTYSDSTESNSTALARRLQDIFEFDHPEAVIEEYPCWLLQSVLLQGYMYITAKHICFYAYLPKKAHEVVKSGYLSKSGKRNPKYNRYWFRLKGDVLAYYKDPSNVYFPSGQIDLRYGISASVNDKKDGLGFTVVTHHRTYHFKADSAPSAKEWVKSLQRVIFRSHNEGDSVKISLPIENVIDIEDTQMLEFADTCKIRVIDNDETYAIDEYFFSFFSFGKDAINVLKILIEDASSSARDAAILKATQEQQDERQQQQQQPVAASARSSTSVSRRPSAPLRLRTNKLPDAVKATLSPLSAHSPSALSPRASMDAAHASFDAFRGFRRRSLDLSTIIRDSSPRRSFSGNRRSMSRNRLDESRHTPHNQGSTDSYVQSSMEDPSYSGMVASSSEDPSASQILRGSDVFQNPTMHRSASVSRTELEKNQQREPRSPPALAAYSGQRAATTGSINDGDKPPATPTLQSITKMGAFPLQRVGAFAEYLNSTSSKLGSMLATESMGYVEKVSGMWRGGRKHYDAPPEIKTDDEDLYEDAEGKIQTSMDRFRAHFALPETEKLQATYFGYILRVLPLYGKIYISDKSFCFRSLLPGTRTKLILPLKDIENVDKEKGFRFGYSGLVIVIRGHEEVFFEFGQAELRDDCAVTLLQSLETTRYLKETGDLDMEEKEEEVNAMAERDALKEARQVEEFHDHELRLPKECAGASDAPTILFDDPKASFLNFKPSHSMKITCLTIGSRGDVQPYIALCKGLIAEGHKPRIATHAEFKDWIEGHGIEFAKVDGDPGELMRLCIENGTFTWAFLREANSMFRGWLDELLVSAWEACQGSDLLIESPSAMAGIHIAEKLSIPYFRAFTMPWTRTRAYPHAFVMPEYKMGGAYNYMTYVMFDNIFWKATAHQINRWRNNTLKLPNTSLEKMQPNKVPFLYNFSEYVVAPPLDFSDWIRVTGYWFLDEGSDFQPPKELTDFIAKARADEKKLVYVGFGSIIVNDTAKMTQEVIDAVLKADVRCILSKGWSDRVAKPEDAGGTKKDEPVMPPEIFVIKSAPHDWLFSQIDAAAHHGGSGTTGASLRAGIPTIIRPFFGDQFFFGARAEDIGVGICLKKWGAVSFARALWEATHNDRMIVKARVLGEQIRSERGVENAIQCIYRDMEYATSLIKRKAGKHAQAEEYDDEEAEESWTFIGSDEPDPDMTTKKLSEIGGVPGLPESKPLGNRVMRVSPSASQQQQAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9B4</accession>
    <name>E3Q9B4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Enoyl-CoA hydratase/isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_01788</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Siderophore biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091313.1">
        <property type="nucleotide sequence ID" value="XM_008093122.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9B4"/>
    <dbReference type="STRING" id="645133.E3Q9B4"/>
    <dbReference type="GeneID" id="24407153"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01788"/>
    <dbReference type="eggNOG" id="KOG1680">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_7_6_1"/>
    <dbReference type="OrthoDB" id="2139957at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000074">
        <property type="entry name" value="Enoyl-CoA hydratase (AFU_orthologue AFUA_2G10650)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF158">
        <property type="entry name" value="ENOYL-COA HYDRATASE (AFU_ORTHOLOGUE AFUA_2G10650)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ27293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="278" mass="30222" checksum="8D0F93559E5BFBB8" modified="2011-01-11" version="1">MTSSPKQTSPPATPEFLKLSYPAPRVLLVRMDRPRDLNVMSTAAQWEMNSVWKWFDQEPNLSVAVITGTGRAFSAGADLKEWSASMAANADPSKRMGNAPAFTPLSRRLGKKPVIAAVNGLAMGGGCEFVVNCDIVVAAEDAYFGLPEVKRGIAAIGGALPRLIRTIGLQRASEFALTGRNVSAQEMAEWGVVNKVVPKENVLDEAVRYAKMIAANSPDAIICTRAGLRQGWETASVEKATEWTLENEFAELQKGENIIEGLKAFSEKREPNWKGSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9Z6</accession>
    <name>E3Q9Z6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_02828</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091704.1">
        <property type="nucleotide sequence ID" value="XM_008093513.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9Z6"/>
    <dbReference type="STRING" id="645133.E3Q9Z6"/>
    <dbReference type="GeneID" id="24408193"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02828"/>
    <dbReference type="eggNOG" id="KOG2175">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004909_0_1_1"/>
    <dbReference type="OrthoDB" id="27483at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030289">
        <property type="term" value="C:protein phosphatase 4 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072542">
        <property type="term" value="F:protein phosphatase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055236">
        <property type="entry name" value="EVH1_PP4R3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006887">
        <property type="entry name" value="P4R3-like_central_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051137">
        <property type="entry name" value="PP4R3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23318">
        <property type="entry name" value="ATP SYNTHASE GAMMA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23318:SF0">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22972">
        <property type="entry name" value="EVH1_PP4R3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04802">
        <property type="entry name" value="PP4R3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PP4R3 EVH1-like" evidence="5">
        <location>
            <begin position="13"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="Serine/threonine-protein phosphatase 4 regulatory subunit 3-like central" evidence="4">
        <location>
            <begin position="154"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="699"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="717"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="736"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="761"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="804"/>
            <end position="817"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF22972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ27684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="856" mass="97154" checksum="807908D0D0A09B73" modified="2011-01-11" version="1">MMAQPVPHHATDKKRVKVYELRNNDWFDRGTGFCTAAFMQTEEGQPRDPRVVVESEDHPDRLLLETKICKEDGFQKQQETLIVWTEPSNGIDMALSFQEADGCALIWKFVNSVQQTFQGGMAGADADDSLSDDLPMDMPTSFSLPSAEIGNLPEIETSMRIMSQTVNGREALCKCISQDGYIRKLIPLVEMAEDLESLPDLHRLCNIMKTVILLNDTQLIEHVVSDDCVLGVVGALEYDPDFPSHKANHRHWLDNQGRYKEVVPIEDDNIRRKIHQTYRLQYLKDVVLARILDDPTFSVLNSLIFFNQVDIVQHLQGNGGFLNELFSIFKATQPDQMRKKEAVLFIQQCCAIAKNLQPQARQTLYNHFISHGLLQVINFGLRHPDVSVRVGATDVLVSLIDHDPHMIRGTIYRQLHDGQPPLTDSLIDLLLVEVDLGVKSQISDALKVLLDHGPPIQSQEAFAKANGEFPGRRPQAAESPQHELFLSHFYSTSAQRLFRPLIDLQGRTDMTFPVQQASMFTYLIEILCFFIRQHVHRSKFFVLQQDLLRRIAQLFACPEKYLRLVAIRFFRNLAGMQDNFYDKHIMEHGILEPLLDMVSRSMPRDNLLSSACIEFFVFITQQEHRKEMNKFLVQNHRERLVALSYMDTFRNIIVVYDQTQGHTIDFYTESEEDHARRNANPNQRMMEHISVDQAEEDYFNTSDDEDGPESRALDKVQPTNGSAASTPTSKPLVDYPSDEEVDENADPEVLPTSSEKHDGTDGASDTSSESSSVAPPERLSEKRRREEDDDDELGKLMQNKRRNSSSAGSNASMTSSMVRRKKTFADRPNAATPKKIAISISPSVKTGGVARSDDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>E3QA35</accession>
    <name>E3QA35_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Ubiquitin-conjugating enzyme E2 2</fullName>
            <ecNumber evidence="3">2.3.2.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">E2 ubiquitin-conjugating enzyme 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="19">Ubiquitin carrier protein UBC2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Ubiquitin-protein ligase UBC2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">GLRG_02867</name>
    </gene>
    <organism evidence="24">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="21">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="3"/>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091743.1">
        <property type="nucleotide sequence ID" value="XM_008093552.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QA35"/>
    <dbReference type="SMR" id="E3QA35"/>
    <dbReference type="STRING" id="645133.E3QA35"/>
    <dbReference type="GeneID" id="24408232"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02867"/>
    <dbReference type="eggNOG" id="KOG0419">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030988_10_2_1"/>
    <dbReference type="OrthoDB" id="9984419at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033503">
        <property type="term" value="C:HULC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990304">
        <property type="term" value="C:MUB1-RAD6-UBR2 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097505">
        <property type="term" value="C:Rad6-Rad18 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990305">
        <property type="term" value="C:RAD6-UBR2 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990303">
        <property type="term" value="C:UBR1-RAD6 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034620">
        <property type="term" value="P:cellular response to unfolded protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071629">
        <property type="term" value="P:cytoplasm protein quality control by the ubiquitin-proteasome system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007535">
        <property type="term" value="P:donor selection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042275">
        <property type="term" value="P:error-free postreplication DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070987">
        <property type="term" value="P:error-free translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042138">
        <property type="term" value="P:meiotic DNA double-strand break formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031571">
        <property type="term" value="P:mitotic G1 DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000639">
        <property type="term" value="P:negative regulation of SREBP signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090089">
        <property type="term" value="P:regulation of dipeptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009302">
        <property type="term" value="P:sno(s)RNA transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030435">
        <property type="term" value="P:sporulation resulting in formation of a cellular spore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120174">
        <property type="term" value="P:stress-induced homeostatically regulated protein degradation pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031509">
        <property type="term" value="P:subtelomeric heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000722">
        <property type="term" value="P:telomere maintenance via recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071596">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process via the N-end rule pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd23790">
        <property type="entry name" value="UBCc_UBE2A_2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000007">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 21" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 21" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0749">Sporulation</keyword>
    <keyword evidence="13" id="KW-0804">Transcription</keyword>
    <keyword evidence="12" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 21" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="22">
        <location>
            <begin position="4"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="20">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00039884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00041569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00042179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00042190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="EFQ27723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="151" mass="17142" checksum="656AF90E4C1E6269" modified="2011-01-11" version="1">MSTAARRRLMRDFKRMQTDPPAGVSASPVPDNVMTWNAVIIGPADTPFEDGTFRLVMQFEEQYPNKPPAVKFISQMFHPNVYATGELCLDILQNRWSPTYDVAAVLTSIQSLLNDPNTGSPANVEASNLYKDNRKEYTKRVRETVEKSWED</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBI4</accession>
    <name>E3QBI4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein bL17m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_03467</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the bacterial ribosomal protein bL17 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092343.1">
        <property type="nucleotide sequence ID" value="XM_008094152.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBI4"/>
    <dbReference type="STRING" id="645133.E3QBI4"/>
    <dbReference type="GeneID" id="24408832"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03467"/>
    <dbReference type="eggNOG" id="KOG3280">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074407_1_2_1"/>
    <dbReference type="OrthoDB" id="275000at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1030.10:FF:000005">
        <property type="entry name" value="Probable 50S ribosomal protein L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1030.10">
        <property type="entry name" value="Ribosomal protein L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01368">
        <property type="entry name" value="Ribosomal_bL17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000456">
        <property type="entry name" value="Ribosomal_bL17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047859">
        <property type="entry name" value="Ribosomal_bL17_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036373">
        <property type="entry name" value="Ribosomal_bL17_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00059">
        <property type="entry name" value="L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14413:SF16">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL17M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14413">
        <property type="entry name" value="RIBOSOMAL PROTEIN L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01196">
        <property type="entry name" value="Ribosomal_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64263">
        <property type="entry name" value="Prokaryotic ribosomal protein L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01167">
        <property type="entry name" value="RIBOSOMAL_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 8 9" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ28323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="195" mass="21945" checksum="57E651B166A147BF" modified="2011-01-11" version="1">MAGGLVKYRHLSRNSSARQALLRGLVTSLVAHEHIHTTYAKAKEAQRLAEKLITYAKRDNEETRRKAQAILYTPHDLLPKLFGELRERYSERPGGYTRVLRTEPRNTYDQAPSAILELVDGPRDARFMMTAKAVAFDKDAGKKHTELTKKNVAKVTRYRKDGKSVFADMVASFRQLTARSNGGKGKKAVTEEAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBT0</accession>
    <name>E3QBT0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_03563</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092439.1">
        <property type="nucleotide sequence ID" value="XM_008094248.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBT0"/>
    <dbReference type="GeneID" id="24408928"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03563"/>
    <dbReference type="HOGENOM" id="CLU_3087114_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ28419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="52" mass="5862" checksum="E21760DBE451EE14" modified="2011-01-11" version="1">MTASHIGRLRYLEYQKSSRQQLKQVAMTSGMPPVNTTASLPEQEEIVCEGYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCE9</accession>
    <name>E3QCE9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Triose-phosphate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_03681</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homooligomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TPT transporter family. SLC35D subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092557.1">
        <property type="nucleotide sequence ID" value="XM_008094366.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCE9"/>
    <dbReference type="GeneID" id="24409046"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03681"/>
    <dbReference type="eggNOG" id="KOG1441">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033641_3_0_1"/>
    <dbReference type="OrthoDB" id="10261634at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="65"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="207"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="274"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="333"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="10">
        <location>
            <begin position="69"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ28537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="360" mass="39134" checksum="598CB519F36EBEFD" modified="2011-01-11" version="1">MAESSNFKNEARRSEEGQGLLNGDEKRIDESYDLEANASPATDPGSNAERNRNPVEYTISPQVKFGWLSAYFMFSLVLTLYNKLILGAFPFPWLLTSIHATCASLGCYMLMQCGYFTMSHLGRRENLTLLAFSLLFTTNIAASNLSLAMVSVPFYQVLRTTVPVFTVLIYRVVFGRTYENMTYLTLVPIMIGAALTTIGEYTFTDLGFLLTFAGVVLAAVKTVATNRIMTGPLALPAMEVLLRMSPFAAMQSLACSIAAGELGNLNTMRVEGNISLATVIALLGNGILAFALNVASFQTNKVAGALTMSICGNLKQCLTVGLGIVAFGVEVHLFNGSGMFLTMIGAAWYSKVELDRRSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDP6</accession>
    <name>E3QDP6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04128</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ28984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093004.1">
        <property type="nucleotide sequence ID" value="XM_008094813.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDP6"/>
    <dbReference type="GeneID" id="24409493"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04128"/>
    <dbReference type="eggNOG" id="ENOG502S5DH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084254_0_0_1"/>
    <dbReference type="OrthoDB" id="4510061at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ28984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="183" mass="20721" checksum="1EBCDD34DDC37612" modified="2011-01-11" version="1">MDGFNEYRIIRVAEVLDDFRTLQFYIAAAPSEPANMEDYWTEGWAALRQCSLDGQHILNCAADTSVPQASGGSAEQEKAELKQCLLDAFARRHECQKIYLRQAAAQRWISHRDSILQGESPNSRNGPQLRACDQRLRTELSMITDDAIYTQLQASDCAMGRWTAEDPSSRGVQRWLRARRPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDY2</accession>
    <name>E3QDY2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Extracellular membrane protein CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_04214</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093090.1">
        <property type="nucleotide sequence ID" value="XM_008094899.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDY2"/>
    <dbReference type="STRING" id="645133.E3QDY2"/>
    <dbReference type="GeneID" id="24409579"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04214"/>
    <dbReference type="eggNOG" id="ENOG502S2Z9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003716_0_0_1"/>
    <dbReference type="OrthoDB" id="3946741at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549:SF30">
        <property type="entry name" value="MID2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179647" description="Extracellular membrane protein CFEM domain-containing protein" evidence="6">
        <location>
            <begin position="22"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="170"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="281"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="331"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="512"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="548"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="175"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="335"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="349"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="431"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="556"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="599"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="638"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="659"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="780"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="799"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="822"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="856"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="913"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="943"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="958"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="977"/>
            <end position="988"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ29070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1081" mass="113764" checksum="1BB58E0CE5406AF7" modified="2011-01-11" version="1">MAPKPLLWILSLILLASFTTATTFNLSSEITRFVPSCARECFRSHLSANYAISTCGSAPSLQCLCAIAGFSGLTIGEGAVQCIVAEKSIGFCRESDAPQTVIDAAYQMCAHQPSAIRPTHTAIIATLILPTSGGIIVVPPRATTPLIPPTSTIHTTTSLPTTLISATGTPSIPQTLTTLTRSNTSRISTSSSLITTPPLPPSSTTTPSETAAPVPGAEEANSGPSEGLGTGQVAGLAVGLAAAFGLAILAICLARRRRRKNYPDVKTGFFPVREKDSWEFHPQEGPANIFHISPPVHHSQSPSLSPRPPPAARTRASGRLSWWPGAVGLAVSRPESPPPALRPPPPQQNRPTSRLLPAKPSLSSPKPVLSLKIPQIDLSSSSPPRPQEQRGSQPTNSQIFKTAKLTAPPKSHYNARESTMTEFEEDGAITSARSARSNSIWRPPSATVGSNPKSATFYVADKNGNWVLGDSRSATHMAQIAELDASGASEGGGAREKPSYAESAMLAATATTAGMGHGGGSPVAPSAARMPPPPLLLPAAEIVRTGALAAPPAAHQSRSSSVYSQGTTRPNTGIQTGGVSHPVPSMSFSHPEPPRRRSNSLGRRSSSNAKSGATGAVTGTAAMASTVNAPKRSDSHDSQASSTTIASSVASGDPEPVIEQSSLSPVVESPASNASPSGRSPVSYPPIPGRTSSKPRNDHLRLLAPPTRTYGGFPPGQPSPTLGMMQQQQQQQARNGPYIASYDVPRKPIARPRPAGADPNRVATGSPSLRLVTPSPPPRAEGRQQEQKRDSALTQRPPQMRPLYPPPLQPQRPRIESSNSHPQPQTAQVQQAPLNREPQSATVHRALWGNPPPRSQPQQQQQEQQQPAYSSLPSQQQQQQPWPQPSQQSFSQRQRRRSQEKRQSFQPTTLPEQSPPPKQQLPARPSPGSPSPHHIATQALRRPAPTFAPSPASSSASPSPPTTTAPPPRPASPPATSPSVATPSTTSSLLSKRLGHERAAALALPTAGIRHSPNWRPSRPGGAAGAGGGTDMLLSPNSFFPATPGFPSRSGAREGDLPSTPTWQPKLTPTRRGDDLFLNVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDZ3</accession>
    <name>E3QDZ3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_04225</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MSOX/MTOX family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093101.1">
        <property type="nucleotide sequence ID" value="XM_008094910.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDZ3"/>
    <dbReference type="STRING" id="645133.E3QDZ3"/>
    <dbReference type="GeneID" id="24409590"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04225"/>
    <dbReference type="eggNOG" id="KOG2820">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007884_0_1_1"/>
    <dbReference type="OrthoDB" id="2219495at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050031">
        <property type="term" value="F:L-pipecolate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004657">
        <property type="term" value="F:proline dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008115">
        <property type="term" value="F:sarcosine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045170">
        <property type="entry name" value="MTOX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10961:SF45">
        <property type="entry name" value="FAD DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10961">
        <property type="entry name" value="PEROXISOMAL SARCOSINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178396" evidence="7">
        <location>
            <begin position="22"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="8">
        <location>
            <begin position="8"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="387"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ29081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="412" mass="44488" checksum="DEAEADB3D2D90442" modified="2011-01-11" version="1">MSSASSSVLIVGAGVFGLSLAHELAANRGYTSITVLDRFLPPVPDGSSVDVSRIIRTEYADPLYSSLATDALQGWRTSGVYKPHYHESGFVMMADEKERPSPYFEKYRRWRGEAAEGGGPAGVHGHAQRAGGWADAAGAIRALASECTRAGVSFVTGAQGTVVSLQRSGARVTGVRTAAGTTWEAERVVLAMGAWTNRVVPGVGHAVAASGQPVGFIRLSDEEADRVREMPVMINMSTGVFCFPPTPGTNLLKVARHGFGYATEFEAEAGRKVSSPRLVGSNAASEFLPRDADEGLREGVRLFFPEFAEREWAYRRLCWYTDTPEGDFVVDYHPDIKGLFFATGGAGHAFKFLPVIGSHVADSFERKASTALREKWRMRRAVDGETTLRMAGDGSRGGPPLRKLSPQEQAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QED5</accession>
    <name>E3QED5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Beta-eliminating lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_04385</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the threonine aldolase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093261.1">
        <property type="nucleotide sequence ID" value="XM_008095070.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QED5"/>
    <dbReference type="STRING" id="645133.E3QED5"/>
    <dbReference type="GeneID" id="24409750"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04385"/>
    <dbReference type="eggNOG" id="KOG1368">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029381_1_0_1"/>
    <dbReference type="OrthoDB" id="10261951at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008732">
        <property type="term" value="F:L-allo-threonine aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006545">
        <property type="term" value="P:glycine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006567">
        <property type="term" value="P:L-threonine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000030">
        <property type="entry name" value="Low-specificity L-threonine aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001597">
        <property type="entry name" value="ArAA_b-elim_lyase/Thr_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023603">
        <property type="entry name" value="Low_specificity_L-TA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041359">
        <property type="entry name" value="GntG_guanitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097:SF9">
        <property type="entry name" value="L-THREONINE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097">
        <property type="entry name" value="L-THREONINE ALDOLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01212">
        <property type="entry name" value="Beta_elim_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017617">
        <property type="entry name" value="Thr_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aromatic amino acid beta-eliminating lyase/threonine aldolase" evidence="6">
        <location>
            <begin position="30"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="5">
        <location>
            <position position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR017617-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ29241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="391" mass="41298" checksum="C668358238FDAEBA" modified="2011-01-11" version="1">MSPSTVSDVTSGGAFKQNTWVGHFGAAGFDLRSDTMTTPTASMLAAIQSCSLLDDVFAEDPTTIALESHVAKLAGKDAALMVLSGTMGNQLALRSLLTQPPYSVLCDHRAHIIKYEAGGVASLSGAMVKPVVPRNGAYLTLEDIEATADLDDDVHTCPTKVISLENTINGVITPLAEVKRIAEFARKNDIKLHCDGARLWEAVAAGAGSLSEYCSLFDTVSLCFSKGLGAPIGSIVVGSAAHIKHSRWVRKSIGGGLRQSGVVAAPARVAVDETFGRGPSGEGGLLKTSHATAKKIEQLWTSLGGKLTHPVETNMCWLDLDAAGCSTEAFVAFGKEAGLKLIGNRLVVHYQIAQNEDEVLPRLERVFRQALEGHGSGAKQSHGPANIYKPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEQ6</accession>
    <name>E3QEQ6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">phosphoinositide 5-phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.36</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_04506</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the synaptojanin family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.36" evidence="4"/>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093382.1">
        <property type="nucleotide sequence ID" value="XM_008095191.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QEQ6"/>
    <dbReference type="GeneID" id="24409871"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04506"/>
    <dbReference type="eggNOG" id="KOG0566">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003016_2_1_1"/>
    <dbReference type="OrthoDB" id="405996at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043813">
        <property type="term" value="F:phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004439">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09090">
        <property type="entry name" value="INPP5c_ScInp51p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.10.10:FF:000029">
        <property type="entry name" value="Inositol polyphosphate 5-phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046985">
        <property type="entry name" value="IP5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000300">
        <property type="entry name" value="IPPc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002013">
        <property type="entry name" value="SAC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200">
        <property type="entry name" value="INOSITOL 5-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200:SF257">
        <property type="entry name" value="PHOSPHOINOSITIDE 5-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22669">
        <property type="entry name" value="Exo_endo_phos2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02383">
        <property type="entry name" value="Syja_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00128">
        <property type="entry name" value="IPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50275">
        <property type="entry name" value="SAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SAC" evidence="10">
        <location>
            <begin position="185"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1007"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1064"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1273"/>
            <end position="1295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="52"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1007"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1144"/>
            <end position="1160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ29362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1295" mass="142831" checksum="EDE47B5130DE479E" modified="2011-01-11" version="1">MDNINSGSWPAQVPAPEKSSRLYIRDYPHRSIALVSSSHALIFRYSSVSTGTNGSLTSLASTRSRPNGDGAASKCMVEFTQITKKTLTDYRPLTPRPIFGTLGLISVEGDVFLSVVTHATRVATLRPGETVERIASVAFFCLNSSEWDDVVSLDPLDSEASDASALYGQNLRGREVQVEHPCTDLRKLLGNGTFYYSTDFDLTNRLQDRTVNSYTFDIDNFDDSYLWNSYMISPLVQFRSRLLPQEREALDSSRFLTSAIRGFCRTMAIPQTSAPLKTRSSGLPSYLTVVSRLSCRRAGTRFNSRGIDDDGNVANFVETETIYWSPGGTLFSYAQVRGSVPLFWEQTAELIPGKQNITVIRSPEGAQPAFNKHFADLEQAYGAVHVVNLLSEGKPGEAQLSQLYHLGIEHCPLSQVGEEESQDHALLRETHYDFHAETKGPGGYEAARQIRRYIEKSIDGFAYYLAEESDDGATDNNDYQDSNRMVVVLQQEGIFRTNCLDCLDRTNLIQTLISQMATEAFLSHRGEYATSDFWMRHSTLWADNGDALSKIYAGTGALKSSFTRSGKMSLAGAVADMRKSVQRLYHNNFTDSARQTTIDRLLGRLVNQTPVLLFDPISDYVSSELTKRSAEFSSVQDITMLVGTFNLNGRTEGVDSDLTPWLAPEELGDVLPEIVVVGFQEIVELSPQQIMNSDPSRKQLWEAAVRRCLNKRSKALGGERYVLLRSGQLVGAALCIFVKASALANIKNVEGSVKKTGLSGMAGNKGAVAIRFDYANTHICFVTAHLAAGFSNYDERNRDYATIHHGLRFQRNRGIDDHDAVIWLGDFNYRIGLGSESARSLIKKKDLETLYENDQLNLQMIAGLAFPFYSEARINFLPTYKFDLGTDEYDTSEKARIPAWTDRILRKGANLRQLAYNSAPLKFSDHRPVYAVFQCNVSIVDEALRDRISKELYHRRKADVGDATANLDSEDTEDEDLIGYEAIEPGLPPASSDRQKWWLENKQQARVDIKQPKAPDGHATVLNPNRPPNPFAPTGEPDWVNVPRSRLSSFSSVSTSPYEHVYAPTDLSSPASNRIARKLPPPFDQSALSSKVGGLIIKDDKSQRGETPPPPPPPRRQTGANAAVQQPPLIPSNRSQNPTPPRPSSAISQLSQLSSQSKSKPAPPVAKKPAHLATSPNLSSSGAVLYKDDPTERPPLPVRASTGFTNLSAGLEGGMNRKPIGTPAKSPKRADTLDPEPGRQSPMVGAVALPGMRASEARAKPKIPARKPVDLLDSLADEGPSDMGSWETLVPTTQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QF03</accession>
    <name>E3QF03_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_04585</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093461.1">
        <property type="nucleotide sequence ID" value="XM_008095270.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QF03"/>
    <dbReference type="STRING" id="645133.E3QF03"/>
    <dbReference type="GeneID" id="24409950"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04585"/>
    <dbReference type="eggNOG" id="ENOG502QQ5E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024508_3_2_1"/>
    <dbReference type="OrthoDB" id="431212at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005345">
        <property type="term" value="F:purine nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015853">
        <property type="term" value="P:adenine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015854">
        <property type="term" value="P:guanine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045018">
        <property type="entry name" value="Azg-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43337">
        <property type="entry name" value="XANTHINE/URACIL PERMEASE C887.17-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43337:SF1">
        <property type="entry name" value="XANTHINE_URACIL PERMEASE C887.17-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="239"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="317"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="452"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="476"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="539"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="566"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ29441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="582" mass="63004" checksum="7B8781DD2AF1E6CC" modified="2011-01-11" version="1">MGFVQTWNAKIAAGPVGRWFQLEGSGHPRERKGSLFFTELRAGLVSFFAMAYIIAVNSSIVADTGGTCVCPRTQEDFTCDHDQDYLLCVAEVKRDIVTATAAISALATFFMGLLANMPVGVAPGMGLNAYFAYTVVGYHGTGAVPYQVALTAIFIEGFVFFGLALLGMRQWLARAIPRCIKLATGVGIGLFLTLIGLTYSEGIGLVVGATSTPLELAGCLQSELIDGLCPSSTKMRSPMMWIGIFCGGILTIMLMMYRFKGAILAGIILVSIISWPRGTDVTYFPYTAVGDSNFDFFKRVVDFHPIQRTLNVQEWNIGGYSGAFGLALVTFLYVDILDCTGTLYSMARFANLIDEETQDFEGSSVAYMVDALSISIGAIFGTPPVTAFVESGAGISEGGKTGLTAMATGFCFFVSIFFAPIFASIPPWATGCVLILVGSMMVRAVTEINWRYMGDAIPAFITLALMPFTYSIADGLIGGVCSYILINTLVWVIEKASGGRIVPHNKHEKDPWTWRIPGGILPPWVRRLLKGKKDFWRSDDHNAASNPEPQPLEKTVSSERGVSMNGKDREVGEIVTPHGDRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QF07</accession>
    <name>E3QF07_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">SH3 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_04589</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093465.1">
        <property type="nucleotide sequence ID" value="XM_008095274.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QF07"/>
    <dbReference type="STRING" id="645133.E3QF07"/>
    <dbReference type="GeneID" id="24409954"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04589"/>
    <dbReference type="eggNOG" id="KOG3771">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025518_1_0_1"/>
    <dbReference type="OrthoDB" id="10255128at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043332">
        <property type="term" value="C:mating projection tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031097">
        <property type="term" value="C:medial cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990528">
        <property type="term" value="C:Rvs161p-Rvs167p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051666">
        <property type="term" value="P:actin cortical patch localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097320">
        <property type="term" value="P:plasma membrane tubulation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07599">
        <property type="entry name" value="BAR_Rvs167p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000100">
        <property type="entry name" value="SH3 domain-containing YSC84-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046982">
        <property type="entry name" value="BIN3/RVS161-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174">
        <property type="entry name" value="BRIDGING INTEGRATOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174:SF2">
        <property type="entry name" value="SH3 DOMAIN SIGNALLING PROTEIN (AFU_ORTHOLOGUE AFUA_5G07670)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03114">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14604">
        <property type="entry name" value="SH3_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51021">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="BAR" evidence="6">
        <location>
            <begin position="7"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="416"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="276"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="390"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="132"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="287"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="322"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ29445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="474" mass="52174" checksum="B5CEA25E462A70DE" modified="2011-01-11" version="1">MQSVQRQFGKLMSKSPGDNAKIAAVLHDYEDADSLLSKIIENTRTLRDAWVAMVTSQWAIVNEYQGLYDPIVGASEGHARPGVETPQLQLDRTFKLSGVYSDLKDELIGEVAAIDSQVIRPATEAREFIQPLRKTIKKRENKRLDYEKAQEKVKKLQKKTGRTPKEDAQLSKVEFEMSCASEEFEVADVHLRDALPPIIEAIFALIPHLLASHVCIQNRLLGLYYTALHNYCEDHGFPSPPPPMENVVSAWSATFLPVQREVEAISCIAHGKNWRQPARVGDDGQSRKSSAYPVSSRNGFARTPSDTSESAAPTPRTMRIPSTTSANRSASTSDFSPQPSPQSSSISVSRSQLGLPTDFTTATALGQPQGASNVSPAYISSRAEYFGHQSRLPSDHGNVVAKKKPPPPPPAKRLKAAEEYVVAQYDFSGGDGDLSFREGDRIRIVKKTETDQDWWMGELGGVKGSFPANYCKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFE3</accession>
    <name>E3QFE3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kinesin light chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04725</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093601.1">
        <property type="nucleotide sequence ID" value="XM_008095410.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFE3"/>
    <dbReference type="STRING" id="645133.E3QFE3"/>
    <dbReference type="GeneID" id="24410090"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04725"/>
    <dbReference type="eggNOG" id="KOG1840">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_125_3_1"/>
    <dbReference type="OrthoDB" id="4842036at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="entry name" value="Nucleoside phosphorylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053137">
        <property type="entry name" value="NLR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082:SF11">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082">
        <property type="entry name" value="ATP/GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="Purine and uridine phosphorylases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NB-ARC" evidence="1">
        <location>
            <begin position="326"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="656" mass="73537" checksum="E11190C2718AC007" modified="2011-01-11" version="1">MSTVPVTARKKLARGNYRIGWICPLHVDMQAALAMLDEVHENLPQPCTDPTIYRLGSISGHNVVIASLHQPGNCTAAMVANSMQSTFRNLEFGLLVGTGGGVPTRSEAGMIRLSHVVVSKSKDAHSGAVYYSQIKAEDGVFKRTGYIDSPPPILLHAARSLEIDLEASEDCPISSNIERILSNQMLRSKYKHPGVSKDHMRGPEDEDTGGIIVHRGTIASGELLLRDAGLRDKLAKEHGVLCFEMEAAGALTDFRCLVIRGISNYCDALKNDDWHGYASAAAAAYARELFFTYRLRWRKSMTHVRPRHFIVPFTQNRDFLGREIFLEELRAKLCVDDRPRRLAITGLGGIGKTQVALQTAFWFKENRPTWSVFWVQAYSMSAFEKACSGIIDRSGIQVAKDEDPKETVQRFLNSRDSGNWLFIVDNADDGQTMFRSGNSPGISNFLPENEDGRILFTSRFRKLAFELAGKEVLELEKMTTSEARKFFDQVMPEELTRPIGLVEDLLAQLEHLPLAIYQAAAYLRNNCISTSIEDYLSTLRGTEKEAAGLLSREYRDHTRYDDEDIGHAVGTTWLVSFGQMEQMDDVKAAMVLLQFISQNEPTSIPMDLLPRRNIEGLHYASGILASFAFLDKRPGTNLLSMHRLVHLASRIWFEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFU1</accession>
    <name>E3QFU1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_04920</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093796.1">
        <property type="nucleotide sequence ID" value="XM_008095605.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFU1"/>
    <dbReference type="STRING" id="645133.E3QFU1"/>
    <dbReference type="GeneID" id="24410285"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04920"/>
    <dbReference type="eggNOG" id="ENOG502S903">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_662239_0_0_1"/>
    <dbReference type="OrthoDB" id="5428787at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178439" description="Apple domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ29776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="359" mass="38914" checksum="1B3352A1D63A9E7D" modified="2011-01-11" version="1">MVLIKSLLTAIVLAARIANAEEAVSEVQLPQSPPRTVTAEQGCYTDFAERQRDSVPTYSRLYSYTFPVTEYTYTTPTTSTVTITPTISTRGVGTITSTVTTTTHVSSFSTVTVEAPAGFTPIAAASNRTGGAYGRLGSLDEAPISPADADRSFGNSLSGDEEGRRTARPFLWPQAVVCEKVVRVFTTTTSTITATRAATTTTTLLGPTQQTVVATTTPTTTTTTTTTTSTITDVIANPTRTVYEACQTNNVQASHGQPLSFFVEALYYWPVTSEERHTDTPENCCVACQTTTDCSGSLYHFFSGTCYIFKNRDKRRQCQSRLKLRSQTNITTNGVFWASNGRCGSWKITDEEPGSSAEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFW8</accession>
    <name>E3QFW8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Trimethyllysine dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_04947</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amine and polyamine biosynthesis; carnitine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the gamma-BBH/TMLD family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093823.1">
        <property type="nucleotide sequence ID" value="XM_008095632.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFW8"/>
    <dbReference type="STRING" id="645133.E3QFW8"/>
    <dbReference type="GeneID" id="24410312"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04947"/>
    <dbReference type="eggNOG" id="KOG3889">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021859_2_1_1"/>
    <dbReference type="OrthoDB" id="408743at2759"/>
    <dbReference type="UniPathway" id="UPA00118"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050353">
        <property type="term" value="F:trimethyllysine dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045329">
        <property type="term" value="P:carnitine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00250">
        <property type="entry name" value="CAS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.130.10:FF:000001">
        <property type="entry name" value="Trimethyllysine dioxygenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050411">
        <property type="entry name" value="AlphaKG_dependent_hydroxylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012776">
        <property type="entry name" value="Trimethyllysine_dOase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02410">
        <property type="entry name" value="carnitine_TMLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696">
        <property type="entry name" value="GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696:SF51">
        <property type="entry name" value="TRIMETHYLLYSINE DIOXYGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0124">Carnitine biosynthesis</keyword>
    <keyword evidence="7 11" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="10">
        <location>
            <begin position="79"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ29803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="364" mass="42049" checksum="C903C15CE788F33E" modified="2011-01-11" version="1">MRPHRAAISDNLNFLQQLGLKISEDVRPSDIKSEEQGITVTWEQDGHQSFYPWHFVKHYLQNDHRCPEKVNYQLWGSDIGSRRPVVDYNQLMASEDESGIAKLTNLIREYGFAFVDKTPFRTPESTQRVLERIAFIRETHYGGFYDFIPDLAMADTAYTNIALPAHTDTTYFTDPAGLQAFHMLSHEAPPGQALPKDGKLGGESLLVDSFHAARILLKEDPKAYEILSKVRLPWHASGNQGITISPDKRYPVLEVDEETGELQRVRWNNDDRGVVPFTKHASPTEWYAAARKWNAILRRRDVEYWVQLEPGQVLIFDNWRVMHGRSAFEGRRRIAGAYINRDDFISRWRNTNFPREHILNQVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGD0</accession>
    <name>E3QGD0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA2/NAM7 helicase helicase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_05062</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ29918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093938.1">
        <property type="nucleotide sequence ID" value="XM_008095747.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGD0"/>
    <dbReference type="GeneID" id="24410427"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05062"/>
    <dbReference type="HOGENOM" id="CLU_874385_0_0_1"/>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="2">
        <location>
            <begin position="5"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ29918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="318" mass="35713" checksum="D94E70D3DF11F607" modified="2011-01-11" version="1">MTFYAGGPGSGKTTWGIRLLRTLGRYNAACSVHSNDLCDDAANKLGATCRNSRVARAYRHERMLRALTGQLEYSQVVPSTMSSQYSQAQRQVIRTVTDIEDTARQENPLARADSLVSLALSIAKNNPDFDEFNALRTSARKTDEELSRLTIEANRLLAYALVQVNILVGTPVALGSIARASKLEHKDLGRWNPHIIFMDETGRMPESQFYIPMAFFKPTWVIAAGDTQQFKPMSKSMDLNGERETGFNLRSIIAKVQTEQLLGRPIDQQPDPAYDDEIKHIDEAQTIAQFEVGHETQTQTNRKENVDQDWETETDSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGD1</accession>
    <name>E3QGD1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_05063</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
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            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05063"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_008455_11_1_1"/>
    <dbReference type="OrthoDB" id="3357846at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
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    </dbReference>
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="MFS multidrug transporter, putative"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS"/>
    </dbReference>
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        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF23">
        <property type="entry name" value="FLUCONAZOLE RESISTANCE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
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    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
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            <begin position="79"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="242"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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            <end position="381"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="426"/>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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            <begin position="461"/>
            <end position="483"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="495"/>
            <end position="514"/>
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    </feature>
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        <location>
            <begin position="79"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EFQ29919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="530" mass="58450" checksum="630A95DDA35FA314" modified="2011-01-11" version="1">MEKGSSPNGSRLSYVSRHTEVQGFSSESEKGIGNTFASQTISRTTWEKYGIENRTDLHLVEFLPNDPENPRNWSDLKKILVSFQLCLLVVAVYAGASIYTVGTQGVQVRFGVSDTVALLGLTVFVLGYGLGLMIWSPLSEVPQIGRNTIFIPALVIFILAQVPTALATSIGMLLIFRFIAGFFGSPILGAGDGILTDMYESRKHMYAMVGFALVGICGPTLGKSKLHFRPIIGGFAVQAKGWQWTMWIVCWASTLVLVVLVLFLPETSAENILYRRTMRLRRVTGDLGFVCEAQLKADNTRGVELLKAHLIRPFTLVLTDPAVFFLNLHSSFTYGFMYIWFESLPLAYKEVYHFDIGTATLALLGLIVGVLVVIPPFFLYYRLRIEPKYARNGKVKPEKHLHPAMLGSLLLPGSLVWFGWTARPSIHWAVPIAGSSLFTAGALLLYISILNYLAESYPKHIASVLAGNELFASMCGATFPLLIPSMFHKFGVLGSSMILAIVAMAFVPIPYVIAMRGPKLRKRSTYAAKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGG3</accession>
    <name>E3QGG3_COLGM</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05095</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ29951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008095780.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="24410460"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05095"/>
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    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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        </location>
    </feature>
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        <location>
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            <end position="180"/>
        </location>
    </feature>
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        <location>
            <begin position="15"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="180" mass="19155" checksum="6EC0E7E5BC0CDA11" modified="2011-01-11" version="1">MSASYYTPQRPYFPSPQHSSSSSAARPAAAGTPAPPSFTPAMRDRQARGKDPYSPHDSPSDSDLDFDGVDSPSRGVGSLGHLGPGHGHAHGGAATGGGVGDGDSHEVRRRKLWAVSVLEDPERLAMYACSRGDSIPGTRLYFTRILCGFDEEPADPRKAASASRRDPRRRSAGGERMGRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGZ2</accession>
    <name>E3QGZ2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Gastric mucin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05274</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ30130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094150.1">
        <property type="nucleotide sequence ID" value="XM_008095959.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGZ2"/>
    <dbReference type="STRING" id="645133.E3QGZ2"/>
    <dbReference type="GeneID" id="24410639"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05274"/>
    <dbReference type="eggNOG" id="ENOG502RVJZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006328_0_0_1"/>
    <dbReference type="OrthoDB" id="5401106at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="479"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="781"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="858"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="480"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="789"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="863"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="890"/>
            <end position="902"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="973" mass="106919" checksum="C2A506A213A3C537" modified="2011-01-11" version="1">MTESAQYHGALVAFEGHGDLVSTQLRLLPTSTQIALLPSVKEYLEPDNPEEPFEARKFVKRVHDAVVKRREVAMVFLSGSTPRRKRLVFMNGGTPSAQTVCIKAISRNVTDGDISKAEAIFNELVKGGVESLTRHPASVGGSFLDTSDDFVEDPITRAMRAADALDRETENLQPPSDMDLTILSLRPRSLSLPMFCFADTYGDTAPFYVFGGHYHEEFGGDEGRPTETAQLRDSTPSLAVTNFDERTSAWFNRESNLTVSGPPRSPSCAGEAYERGDVSSPPSPNPSTMLGVATPRSDVFSIRSTEPIFIEQASLVRMQSSASTHTLKRSKSNGQLTRTSSRYRDTLVRLKHKNSLTEGANADNLANVRSVPGHVLVPEVPQRETKAVEIPKTVYVRSPRANSPVPSPREELAWHHRRITNRYVDRGTDAQDAEQSEDAFLPVLPFHEDLVIHFKDENPDPILEHMIKSFKEGTYPVTVSPGSSRNTSIADGRSTAPNTPPLPTNDFLTKAPTPAIAVGGGEYDPYSYDDTVLARKHPLSAPRSMTVSALPTPAHTPPPTIPEPEDKFHDFKAVKGQTAVAMQNSLRSVLNIYFPPNGRGYSQFGFPLLPEMEGLWKPIFRETDLRESLGKDSRQIDLILAVGAQRGVNKPFVSGVISQLEKLGSKPNGTCRTGRLDFRYLIANAMQSFTAQPLARQTHDNPFTNSYFLATLIVPHLETYLAAHSEVRFLLLDYPPDHLATVLALQKLVGVDMMKVAQVIDAATKEPLLFTHARGNSLGRVSPRNDFVSSSSSSVQSKDSKAAASAPSRDGLAVSKANLLLASTATEIEVATFVSTVRTLLISISKFYLPDKGSKKLGKLRTGNPSPITPQTMSPPISPLSIRSRRHIRTTSSARSSPRTSSITDNIMVRRLKSRRGGDTRPGLGDDGSIMTVDMEFESDLDLEERRLMPMFLKKNHMRKGNSRKALKFLGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QH16</accession>
    <name>E3QH16_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ZIP Zinc transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_05322</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697348">
        <property type="protein sequence ID" value="EFQ30178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094198.1">
        <property type="nucleotide sequence ID" value="XM_008096007.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QH16"/>
    <dbReference type="STRING" id="645133.E3QH16"/>
    <dbReference type="GeneID" id="24410687"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05322"/>
    <dbReference type="eggNOG" id="KOG1558">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027089_1_1_1"/>
    <dbReference type="OrthoDB" id="448280at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040:SF55">
        <property type="entry name" value="MEMBRANE ZINC ION TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G00470)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040">
        <property type="entry name" value="ZINC/IRON TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="255"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="482"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="525"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="41"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="310"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="310"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="344"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ30178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="546" mass="58637" checksum="7E4148AEDECC8862" modified="2011-01-11" version="1">MNCPSRNDDITLEHPDWNQNPPFLAADLTTCEDLNGIANAREQRHARGGAGDGSDGRGDDMNYQTLPHLRPDRRSPVSGGRNYGFRPRNRKVHGGDGHTPLLRASAPEHSALWGWVSWAMSVLGCSAIISALRSPEAVVSFLVASHQTARSVVKRSARSVRRSTCPTGGLGDEDTYNTPLHVGALFIILAVSFLACAFPLAAAATPGVRVPRAFFFAVRHFGTGVLLATAFVHLLPTAFTLLGNQCLSSFWVEDYPAMPGAIALAGIFLVTIIEMVFHPGRHMTCVPGGNRTTDDDDDDAVFSPQSAVSLNNDNSPLEMTQSRGGGAVGSLGRTHARIGRGDDQQAQTRSQTGSRLPKRVDEADRAARLEAAGPVVLSPAQQHQKDILQCMMLEVGILFHSVFIGMTLSVSVGSEFVVLLIAIAFHQTFEGLALGSRIAAIDWPKGSRLQPWAMALAYGCTTPVGQAIGLATHRLYSPDSEFGLVLVGTMNALSSGLLVFAALVELLAEDFLSDESWRVLRGRKRVWACLLVFFGAFGMSLVGAWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIG7</accession>
    <name>E3QIG7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SYO1-like TPR repeats domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_05721</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the nuclear import and ribosome assembly adapter family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094597.1">
        <property type="nucleotide sequence ID" value="XM_008096406.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIG7"/>
    <dbReference type="STRING" id="645133.E3QIG7"/>
    <dbReference type="GeneID" id="24411086"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05721"/>
    <dbReference type="eggNOG" id="ENOG502RYAI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028608_0_0_1"/>
    <dbReference type="OrthoDB" id="288703at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13394">
        <property type="entry name" value="Syo1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052616">
        <property type="entry name" value="SYO1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057990">
        <property type="entry name" value="TPR_SYO1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13347">
        <property type="entry name" value="HEAT REPEAT-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13347:SF1">
        <property type="entry name" value="HEAT REPEAT-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25567">
        <property type="entry name" value="TPR_SYO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SYO1-like TPR repeats" evidence="3">
        <location>
            <begin position="409"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="321"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="339"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="358"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00049983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ30577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="674" mass="72768" checksum="0C1A9EB0F3A02E36" modified="2011-01-11" version="1">MGKSRRNRGGQSHRKDPIAKTVKPPSDPELAALREKSILPIIKDLQSSDPKSRTAAAEAVSNIVSNEKCRKLLLREQIVHIILNETLTDASLDSRAAGWDILRVLAEEEESDFCIHLYRQDVLSAMGFASQAILQNVASAATLSKADLKATWAIAEPVIALLSALAEAQDEILEAIVTIEAVKNLLFAIIAYADSPPNICLDALSALLTLSEDNTRLARDVVADDSPKPLTALIKLQGVSGAKGVLACGVLHNILTALQWFDGTPDQKSLSDASLIPTLSSALRDPKQDSDLPPKCQWSNPTEVLQLALEILADIGTTLQQSMRGSGSKDGEEWNGIGDGDDTAMDEDDKDMEHASGDEDNAGEDGNDDDDDDSMDEDALQADMDLVTGVDDDDDEAGMDDLPTLRELVQQAVPQLVALATASSQSEDAAQLQAHALSALSNIAWSVSVFDFSQDHNAAILKAWTPSGKAIWSNVIVPILAANTADVELATKVTSLAWAVSRSLPGRVPLGGDEHNKFMALYQATKGLHQPNANGDKSKDEEPEDPFQGLGVKCIGVLGQLARDPAPIALNREIGVFLTTVVNALPETPAADAVEALNQLFDIYGDEDLACDKEVFWKDNFLPHLEAAQPKVKALVKTIDKRTQPELRTRADEVALNLGRFIQYKKKQQQQQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJA4</accession>
    <name>E3QJA4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_06086</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ30942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094962.1">
        <property type="nucleotide sequence ID" value="XM_008096771.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJA4"/>
    <dbReference type="GeneID" id="24411451"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06086"/>
    <dbReference type="eggNOG" id="ENOG502RW2F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1539947_0_0_1"/>
    <dbReference type="OrthoDB" id="4788795at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180502" evidence="1">
        <location>
            <begin position="21"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="176" mass="18887" checksum="F2F13985760E241F" modified="2011-01-11" version="1">MKLTAGVFSAALGLAFVANAAPAASPENLAPVPSASANATSISPLAAHTPAELPSLHYPYRLPKNGHSAVCEYSNHPMVDAFPAYGLMSKLGATVPDIPGTCGALWDNLRRFPSCAIIFNAWCGPHPKMDGVLIWKLSLPAYCNRGMIESAWWEATFNSFGGLNCVEVEYLEYPFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKN1</accession>
    <name>E3QKN1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">xylan 1,4-beta-xylosidase</fullName>
            <ecNumber evidence="11">3.2.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">GLRG_06563</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>Hydrolysis of (1-&gt;4)-beta-D-xylans, to remove successive D-xylose residues from the non-reducing termini.</text>
            <dbReference type="EC" id="3.2.1.37"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Glycan degradation; xylan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.37" evidence="11"/>
    <dbReference type="EMBL" id="GG697355">
        <property type="protein sequence ID" value="EFQ31419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095439.1">
        <property type="nucleotide sequence ID" value="XM_008097248.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKN1"/>
    <dbReference type="STRING" id="645133.E3QKN1"/>
    <dbReference type="GeneID" id="24411928"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06563"/>
    <dbReference type="eggNOG" id="ENOG502QQ55">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004542_5_3_1"/>
    <dbReference type="OrthoDB" id="47059at2759"/>
    <dbReference type="UniPathway" id="UPA00114"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046556">
        <property type="term" value="F:alpha-L-arabinofuranosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009044">
        <property type="term" value="F:xylan 1,4-beta-xylosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031222">
        <property type="term" value="P:arabinan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044993">
        <property type="entry name" value="BXL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42721:SF3">
        <property type="entry name" value="BETA-D-XYLOSIDASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42721">
        <property type="entry name" value="SUGAR HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180524" description="xylan 1,4-beta-xylosidase" evidence="13">
        <location>
            <begin position="21"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type III-like" evidence="14">
        <location>
            <begin position="729"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="193"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00026107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EFQ31419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="824" mass="90002" checksum="501457C188EACAE0" modified="2011-01-11" version="1">MLRFIEISALLFCGSALVAGFDADSHQKPLVSRTCLPAVEHAANNNAVNSFPDCSRDPLCSNDVCDETLSPKERAAALVAELTIWEKLDNLVNEAPGVPRLAIPPYEWWSEGLHGVASSPGTKFAKSGNFSYATSFPQPIVLGSAFDDDLVKAIGEVVSKEARAFSNRGRSGLDLYVSSISRHIEPEVRDDMLTEPESPNINAFKDPRWGRGQETPGEDPFHLQNYVAAMLTGLEGGDPSKKLIATCKHYAANDFENYKGVDRAGFDANITTQDLSEYYLPPFKTCAVDKKVGSFMCSYNAINGEPLCANPYLLEDILRQHWGWNGDGQYVSTDCDCVALMVSHHHYAPDLGHAAAWAMKAGTDLECNAFPGSEALQLAWNQSLISEKEVDKSLTRMYTALVSVGQFDSARGQPLRSLSWDDVNTKEAQKLAYQAVIEGAVLLKNDGILPLSAAWREKKYALIGPWINATTQMQGNYFGPAPYLISLYQAAKEFGLDFTYSLGSRINSTDDSFKQALDSAHAAALIVFAGGVDNTLEAETRDRKTLAWPESQLDLLRAVSALGKPVIVLQFGGGQVDDTELLANHSINALLWGGYPGQSGGKAVIDLLFGRAAPAGRLSVTQYPASYNEDVPSTDMNLRPGPGNSGLGRTYMWYNGDAVVPYGFGLHYTTFDAKLKARQASALIKTEEVSSLLSNDYVSGTLVWQQILTKPVVSVLITVSNTGNVASDYVALLFLRSNAGPTPQPTKTLAGYHRFRNIQPGDRSEREVSITIERLVRVDELGNRVLHPGSYELFVDLDEKSTHKFKVGGPSVIVEEFPQPRDRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKP5</accession>
    <name>E3QKP5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Sugar porter family MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_06577</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697355">
        <property type="protein sequence ID" value="EFQ31433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095453.1">
        <property type="nucleotide sequence ID" value="XM_008097262.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKP5"/>
    <dbReference type="GeneID" id="24411942"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06577"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_11_5_1"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000149">
        <property type="entry name" value="MFS transporter, SP family, general alpha glucoside:H+ symporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF76">
        <property type="entry name" value="MALTOSE PERMEASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G07240)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="250"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="333"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="367"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="395"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="423"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="461"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="491"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="75"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ31433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="560" mass="62072" checksum="79FBD4F1756DA563" modified="2011-01-11" version="1">MYDTKTPVSTRGDKETGIHHHHHHADDTTVEGAAAVAVVEGRRRRPEDLAADAARAEHQMTLLEAVRTYPKAIGWSVLLSSTLVMEGYDLALLGNLYSSAVFNDKYGAWSEAQGRRVVSAAWQSGLSNGARAGEVLGLVLAGWAADRYGYRLTTMGFLVLMIAFIFVLFFVPNVQILVLGEVLCGIPWGAFQSVTPAYASEVAPVVLRPYLTTFINMCWVIGQFFSAAVNKGSYHHKDEWAYRIPFGVQWVWPVPILIGLFFAPESPWWYVRHNDKAAAKRALLRLTSRNQPKFNPDETIAMIEHTDEMERRAREGVTYRDCFRGVNLRRTEIVVGVWIVQTLGGQNLMGYFAYFLTQAGMDPGNSFSLSMGQYALGMAGTAGSWFLMHRVGRRTIHFSGLCAQCALLLVVGGLSFSGANASVWAIGAVLVLFTFVYDFTVGPVTYSLVSELSSTRLKNKTIVLARAAYNASNIFVNVMTNYQLSSTAWDWGARTALFWAGTCLLSSVWAYFRVPEPKGRTYAELDLLFEHGVSARKFAGTKVDPYSPELGGEEKLTEEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QL21</accession>
    <name>E3QL21_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_06848</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697356">
        <property type="protein sequence ID" value="EFQ31559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095579.1">
        <property type="nucleotide sequence ID" value="XM_008097388.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QL21"/>
    <dbReference type="STRING" id="645133.E3QL21"/>
    <dbReference type="GeneID" id="24412213"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06848"/>
    <dbReference type="eggNOG" id="ENOG502SM8S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023417_2_1_1"/>
    <dbReference type="OrthoDB" id="1919336at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF43">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G01850)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ31559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="435" mass="47542" checksum="967CC04D5D91F626" modified="2011-01-11" version="1">MSFSTIEGDALDDDETADQMVCSPLRRASDASSFMSRGMSLLGGNHDENALELLSHYLSATTISMANGSTPENPFSVQLIPLAFGSDLVLQLLLTQSAVHRAAKSLVSADRVATKYYNQSLRLFQHNISTFMGGQNGEETLILGIGALILCLVETAKGDVNGTILDHLMAAQSLILPFLSANSTLLHKSLKDFLTEYYLYTATVSMISIDARLSDQLFLSNDLLLLATELVASSYIGSLTGCWLDLILLIPSVFDMGRRMMGHAENPDWQPSADDFILFAQLLSQIQNWQPNPTVSENVALAGYIYQKALLLYLHTALHPISQHNDSLHSVAVQSALSGALSHLAQLDPSVRINTSLCWPITIIGSCVTDKGQQAFLHERLGHMFATIGLGNIRQTSVLLQHVWDHNEVTPADVGAGPWNVCRVMNEKQVWISFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QL79</accession>
    <name>E3QL79_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_06906</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697356">
        <property type="protein sequence ID" value="EFQ31617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095637.1">
        <property type="nucleotide sequence ID" value="XM_008097446.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QL79"/>
    <dbReference type="GeneID" id="24412271"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06906"/>
    <dbReference type="eggNOG" id="ENOG502SCEJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076635_1_0_1"/>
    <dbReference type="OrthoDB" id="5408734at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="156" mass="17388" checksum="4CD350DA7B3B41B7" modified="2011-01-11" version="1">MAHNMTDAELDNDWQPNGRRPQSTIARSFSQELADIFRLDDPVTDLDEKIDQRKQIVQSQTSELEALERRIREMEERLKSNGGSLQTSSNQPAAAEAATPALSKEAQEKARSRPGTARQNQPHAPSSANMPPTPTASEGEYEFVGKDDLDDHPPRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLG5</accession>
    <name>E3QLG5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GTPase-activator protein for Ras-like GTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_06678</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697357">
        <property type="protein sequence ID" value="EFQ31703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095723.1">
        <property type="nucleotide sequence ID" value="XM_008097532.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLG5"/>
    <dbReference type="STRING" id="645133.E3QLG5"/>
    <dbReference type="GeneID" id="24412043"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06678"/>
    <dbReference type="eggNOG" id="KOG2128">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009455_0_0_1"/>
    <dbReference type="OrthoDB" id="775356at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046580">
        <property type="term" value="P:negative regulation of Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05132">
        <property type="entry name" value="RasGAP_GAPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.506.10">
        <property type="entry name" value="GTPase Activation - p120gap, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000593">
        <property type="entry name" value="RasGAP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023152">
        <property type="entry name" value="RasGAP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001936">
        <property type="entry name" value="RasGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14149:SF17">
        <property type="entry name" value="GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14149">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00616">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03836">
        <property type="entry name" value="RasGAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00323">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143885">
        <property type="entry name" value="RGC domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00509">
        <property type="entry name" value="RAS_GTPASE_ACTIV_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50018">
        <property type="entry name" value="RAS_GTPASE_ACTIV_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ras-GAP" evidence="3">
        <location>
            <begin position="185"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="58"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="24"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ31703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="779" mass="89335" checksum="1D9419151137686A" modified="2011-01-11" version="1">MSVMLQTPSRASTASSSSFQPLSRQNTMSSYDGSRSARQSKRYSMSALYMSMSANETDLEIEDELAKAQKILRELKSKISSQSKKNFVLEKDVRYLDSRIALLIQNRMALEEQNEVASHLEDATDMQEGAFPNDDKTQKYGNLMFLLQSEPRHIAHLCRLVSMSEIDSLLQTVMFTIYGNQYESREEHLLLTMFQSVLTYQFDNTPEYSSLLRANTPVSRMMTTYTRRGPGQSFLKSVLADRINSLIELKDLDLEINPLKVYERMIEQIEEDTGTLPPSLPKGITAEQAAENPQVQAIIEPRLTMLTEIANGFLTTIIDGLEEAPYGIRWICKQIRSLTKRKYPDANDQVICTLIGGFFFLRFINPAIVTPKSYMLIDGQPAERPRRTLTLIAKMLQNLANKPSYAKEPYMAKLQPFIQQNKERINKFMLDLCEVGDFYESLEMDNYVALSKKDLELSITLNEIYAMHALIEKHNKELCKDDNSHLGIIMSELGGAPPQVPRKENRVINLPLFSRWETAIDDLTAALDITQEEVYFMEAKSIFVQIMRSIPSNSSVARRPLRLERVADAAATSRNDAVMVRKGIRAMELLSQLQELKVIDKNDQFGLLRDEVEQELQHLGSLKDGVIQETSKLEEVYKTIRDHNTYLVGQLETYKSYLHNVRSQSEGTKRKQQKQQVLGPYKFTHQQLEKEGVIQKSNVPDNRRANIYFNFTSPLPGTFVISLHYKGRNRGLLELDLKLDDLLEMQKDGQDDLDLEYVQFNVTKVLTLLNKRFARKKGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMR4</accession>
    <name>E3QMR4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Isoleucine--tRNA ligase, cytoplasmic</fullName>
            <ecNumber evidence="3">6.1.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Isoleucyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">GLRG_07296</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>tRNA(Ile) + L-isoleucine + ATP = L-isoleucyl-tRNA(Ile) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:9666"/>
            <dbReference type="Rhea" id="RHEA-COMP:9695"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78528"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.5" evidence="3"/>
    <dbReference type="EMBL" id="GG697360">
        <property type="protein sequence ID" value="EFQ32152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096172.1">
        <property type="nucleotide sequence ID" value="XM_008097981.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMR4"/>
    <dbReference type="STRING" id="645133.E3QMR4"/>
    <dbReference type="GeneID" id="24412661"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07296"/>
    <dbReference type="eggNOG" id="KOG0434">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001493_1_1_1"/>
    <dbReference type="OrthoDB" id="1706657at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004822">
        <property type="term" value="F:isoleucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990825">
        <property type="term" value="F:sequence-specific mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006428">
        <property type="term" value="P:isoleucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd07961">
        <property type="entry name" value="Anticodon_Ia_Ile_ABEc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00818">
        <property type="entry name" value="IleRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.740.10:FF:000044">
        <property type="entry name" value="Isoleucine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.730.10:FF:000004">
        <property type="entry name" value="Isoleucyl-tRNA synthetase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000023">
        <property type="entry name" value="Isoleucyl-tRNA synthetase,cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000050">
        <property type="entry name" value="Isoleucyl-tRNA synthetase,cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02003">
        <property type="entry name" value="Ile_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033709">
        <property type="entry name" value="Anticodon_Ile_ABEc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002301">
        <property type="entry name" value="Ile-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023586">
        <property type="entry name" value="Ile-tRNA-ligase_type2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00392">
        <property type="entry name" value="ileS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42780:SF1">
        <property type="entry name" value="ISOLEUCINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42780">
        <property type="entry name" value="SOLEUCYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19302">
        <property type="entry name" value="DUF5915"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00984">
        <property type="entry name" value="TRNASYNTHILE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="ValRS/IleRS/LeuRS editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13 16" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="14">
        <location>
            <begin position="12"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="15">
        <location>
            <begin position="691"/>
            <end position="846"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00069879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EFQ32152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1079" mass="124804" checksum="8423CC3162F7762F" modified="2011-01-11" version="1">MSIDFPKEEEAVLQRWREIKAFERQLKLTKGKPLYTFYDGPPFATGLPHYGHLLASTIKDIIPRYWSMKGFHVERRFGWDTHGLPIEHEIDKKLGISGKAAVMKLGLKNYNAECRSIVMRYSEEWRHTVERLGRWIDFDNDYKTMDPSFMESEWWVFKQLFDKGAVYQGHRVMPYSTALTTALSNFEANQNYQDVNDPAIVIAFPLQDDPETNLLAWTTTPWTLPSHLGLAAHPDFEYIKIVDEKSGKKYILLEKLLGTLYKDIKKAKFKILEKIKGKDMIGWKYEPPFNYFYEEYKDVAFRVLNATYVTDDSGTGIVHQAPAFGEDDYNVALAAGIVTENRPPPDPIDDSGHFTSRVSDFVGMHVKEADKHIIKHLKAAGKIVVDSTLKHSYPMCYRSDTPLIYRAVPSWFVRIPEIVPQMLENIKGSHWVPSFVKERRFASWIENARDWNVSRNRYWGTPIPLWVSEDMEERVCVGSIKELRELSGYTGDLTDLHRDNIDHITIPSKMGKGTLKRIEEVFDCWFESGSMPYASQHYPFENVDKFEKSFPGDFIAEGLDQTRGWFYTLLVLGTHLFGRIPFKNCVVNGIVLAEDGKKMSKRLKNYPVPDLVMDKYGSDALRLYLINSPVVRAEPLRFKESGVKEVVQKVLLPLWNSYKFFEGQVSLLKKVESIDYAWNPKALASNENVMDRWILASCQSLLQFVNEEMSAYRLYTVVPRLLGLIENTTNWYIKLNRRRLKGENGVQDTQHALNTLFEVLFTLCRGLAPFTPFITDTIYQKLRPFIPKEAEAEDARSVHFLPFPEVRKELFDEIVERRVGRMQRVIDLVRVSRERRAVGLKTPLRTLVVIHRDPQYLEDLESLSSYIREEMNVRDLVLTSDEAKYNVQYSVTADWPVLGKKLKKDMARVKKALPTLSSDAVKEYSEKKEILVDGIKLEEGDLVVRRGLKEDESSKNLETNSDNDVLTILDAELYVELAHEGLAREVINRVQRLRKKALLQPTDDIKMEYKVISDPDNIGLEEVFVSQTKVIEKALRRPVDKHEIANFEGEVPSAQQKRVIMEEEQEVQRATFLLRLLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMS6</accession>
    <name>E3QMS6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chitin synthase export chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07308</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697360">
        <property type="protein sequence ID" value="EFQ32164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096184.1">
        <property type="nucleotide sequence ID" value="XM_008097993.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMS6"/>
    <dbReference type="STRING" id="645133.E3QMS6"/>
    <dbReference type="GeneID" id="24412673"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07308"/>
    <dbReference type="eggNOG" id="ENOG502QTJE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050424_0_1_1"/>
    <dbReference type="OrthoDB" id="5582162at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022057">
        <property type="entry name" value="Chs7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35329">
        <property type="entry name" value="CHITIN SYNTHASE EXPORT CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35329:SF1">
        <property type="entry name" value="CHITIN SYNTHASE EXPORT CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12271">
        <property type="entry name" value="Chs7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="260"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="295" mass="32138" checksum="81C79EB2551E137B" modified="2011-01-11" version="1">MGSTQFGNFFNFCRDSTLPVCNVLSDSHSQSGPWGGCELTGISLGGGRKLGNLGSILIAAFAIIASIYLLLRSERKKAAVGRREMQLFLASFIIIELCEIFTVGDFPLAGNVRIAFTGIHIGMIVASTWILMLNAVVGYQIVDDGTPLSMGLIMASAAILLGGTLYITLDTGFQWTGYWSSSYQPPNRHIALYVLYQLAPLIFLVAFFVLEAILVIRVLGEMRPMLYLTAALLLFAIGQIFNYVVSSQICNGTNGAVDGALFETFFTLLAVVAVWVFWSSITEDDWPMPVGNNFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMW8</accession>
    <name>E3QMW8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7598 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_07350</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697360">
        <property type="protein sequence ID" value="EFQ32206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096226.1">
        <property type="nucleotide sequence ID" value="XM_008098035.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMW8"/>
    <dbReference type="STRING" id="645133.E3QMW8"/>
    <dbReference type="GeneID" id="24412715"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07350"/>
    <dbReference type="eggNOG" id="ENOG502SAQI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066685_1_0_1"/>
    <dbReference type="OrthoDB" id="5327148at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056019">
        <property type="entry name" value="DUF7598"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24535">
        <property type="entry name" value="DUF7598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7598" evidence="3">
        <location>
            <begin position="14"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ32206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="277" mass="31045" checksum="BFFFCF568834147A" modified="2011-01-11" version="1">MFNLSENSSLRGSGHMILNVFRAFNIIGLLAVSASAWVMIVMSILKGHFAFFVSASHFFTFSVAIFLIISELNVFRHYFERNWPTLSCEHGLSWLGIAMIVMGCQVLANSTNPAFSVETIGLPLWRLILASGILAITFGFFNVISSIVFCDRHNGINARNIRSDGTLASGKNSLVDGYSVRSNSIHNEKQPNKFKRFTQKFPTPWTKSNTTTAARPNISGPFVPDIEQGHTSDRSWDEDRRSPIMPEINRPPTALHPMNTGNTRFTKYSEVSDMTRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QN13</accession>
    <name>E3QN13_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HOOK N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07395</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697360">
        <property type="protein sequence ID" value="EFQ32251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096271.1">
        <property type="nucleotide sequence ID" value="XM_008098080.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QN13"/>
    <dbReference type="STRING" id="645133.E3QN13"/>
    <dbReference type="GeneID" id="24412760"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07395"/>
    <dbReference type="eggNOG" id="ENOG502RS64">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013811_0_0_1"/>
    <dbReference type="OrthoDB" id="49395at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22211">
        <property type="entry name" value="HkD_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116907">
        <property type="entry name" value="Hook domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="206"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="528"/>
            <end position="678"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="776" mass="88428" checksum="2990A30ECC86B686" modified="2011-01-11" version="1">MPYSESAQAALVQWANTFPLDKKADSISDFLDGHLLSQVLQHLDPTFDANPTEGELYDVYRGIVKLVYRECPGLVGQAKLADIRPSAREARPEAISKVQTQRRLRGRTVRLTKCGSQLLAVLFAVAMLGSSNERYVMRITEDIKDMTILMQLQRVTQDMKAVMEEAEAQDLEEASEVGHESHNADLAMEADNIRLRSDLDKKGKLLADMETRLGHLQESYDDLKEEVVRKGRELEAFHSAQDGAGKEVIRSLELKLREQDELIANQEAQAEDDRITKERLMSEVSALKVKAQKLETLDDEVKELRFKNEELSRKANMVERYKQKLEAQSTLSKEMDNLLYEKEQMQRDLIEYEKVLKRNQALEQTNEQYASKLRDYELQYVELDAQRRALHDDAQQLRDRLATLDAQRLSDERWIAELQEQINSGPQVALSPDAGTAGFSLEEELEGAGNSVAPNPALEISRLKAENNLLRSGMGSASENARLRQELEEERRQRERIQGTYNDTFEKHQLAEAQISALIESSGENQVLANLRIQIAQKTQELESEKRRLKEVQAQLSDKDRELLSARTDLSAVAKDSAEALEELKSTDQLISASIREELEAARQQLKNFATDLEEQRTSLINALLEKDKLRKDLDEAREARQDGTEPVEVVQKLQDKVEKLRGRLKERTSQLEKSEQDKYDLQRKLKAAEGGEAAAAQKAASDQIIKNLQRENALIATAWYDLTSRIQSNHVVLQRRNEAPKSWLGKQRQMVNGKYLLLRLFEDIWGLMGGKCSYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNA1</accession>
    <name>E3QNA1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">thioredoxin-dependent peroxiredoxin</fullName>
            <ecNumber evidence="3">1.11.1.24</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Nuclear thiol peroxidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Thioredoxin peroxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">GLRG_07483</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O</text>
            <dbReference type="Rhea" id="RHEA:62620"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.24"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the peroxiredoxin family. BCP/PrxQ subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.24" evidence="3"/>
    <dbReference type="EMBL" id="GG697361">
        <property type="protein sequence ID" value="EFQ32339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096359.1">
        <property type="nucleotide sequence ID" value="XM_008098168.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNA1"/>
    <dbReference type="STRING" id="645133.E3QNA1"/>
    <dbReference type="GeneID" id="24412848"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07483"/>
    <dbReference type="eggNOG" id="KOG0855">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042529_2_0_1"/>
    <dbReference type="OrthoDB" id="338622at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03017">
        <property type="entry name" value="PRX_BCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000157">
        <property type="entry name" value="DOT5p Nuclear thiol peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050924">
        <property type="entry name" value="Peroxiredoxin_BCP/PrxQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42801:SF23">
        <property type="entry name" value="PEROXIREDOXIN DOT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42801">
        <property type="entry name" value="THIOREDOXIN-DEPENDENT PEROXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="9" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="15">
        <location>
            <begin position="63"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="231"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="28"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="231"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="242"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00077538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EFQ32339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="271" mass="28348" checksum="F43B7220C7AAAE79" modified="2011-01-11" version="1">MPVELRKRKAPEPAPAPAPKKASSKIVKAAEKVKGAVKGKAEKPAQKPADKPAEETVEKVAEEPAAANGSDKKVKAVKGETVNLDGFGGEIETNDGEKTTLKELVDKSKAGVVLFTYPKASTPGCTKQACLFRDSYEPLTKTGFAIYGLSMDSAKANTTFKEKQKLPYPLLCDPKATLISAIGLKKPPKSTQRGVFVIDKAGKVLIAEPGSPAGTVEVVTALVEGGNVEGAAEAAAEAAATDAKEEAPNGETKTDEEKKEDAADGTEKKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QP01</accession>
    <name>E3QP01_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_07603</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697363">
        <property type="protein sequence ID" value="EFQ32589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096609.1">
        <property type="nucleotide sequence ID" value="XM_008098418.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QP01"/>
    <dbReference type="STRING" id="645133.E3QP01"/>
    <dbReference type="GeneID" id="24412968"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07603"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_8_0_1"/>
    <dbReference type="OrthoDB" id="3066029at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF64">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11760)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="229"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="308"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="345"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="369"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ32589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="406" mass="43806" checksum="45CE7D1D817D1B18" modified="2011-01-11" version="1">MNTGKSMQEPGGSPGRISLDRRNDDSEEYADIIPPRSKSQHRDSTEQPNLARLPSGVLNFQDDPVSRQKSNVEVPYEIYERFSKHRKYIIVAVISWCGLLSPISSTAVLSALPEVATEYKTTGDIISLSNAMASEPSVWKEAMTASLFLGCSIGTALSPNVAAFFVFRMLTAFAGTSFLVTGPAVIGDLYHPTERATAMGWFLSGTLIGPTIGPVLGGIIVTYTSWRAIFWLQTALAGVGLGGALFFMPDTFSTHDFLSPPQHNPVSSTLPRGVGTWLVRSSVGALPGCMLIYGWAVQERAGGVTVPVIFMFLGGVSQLFCFPSLNTYCLDVIQGRSAEVIAGNFMIRYLFGAAASAIVLPAIQKIGVGWFSTISATFLIIGALGVWAVAIWGRSWRKRTDEKINS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QP77</accession>
    <name>E3QP77_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_07809</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697364">
        <property type="protein sequence ID" value="EFQ32665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096685.1">
        <property type="nucleotide sequence ID" value="XM_008098494.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QP77"/>
    <dbReference type="STRING" id="645133.E3QP77"/>
    <dbReference type="GeneID" id="24413174"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07809"/>
    <dbReference type="eggNOG" id="ENOG502R2UZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007593_1_2_1"/>
    <dbReference type="OrthoDB" id="5945798at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="339"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="277"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="47"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="152"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="339"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="391"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="414"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="471"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="534"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ32665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="543" mass="59327" checksum="5F9F1052D429F7F1" modified="2011-01-11" version="1">MADLIGSGGTASNGNASNSARHRPTGTPNPTSSPSGIRGPRMIMQERAAREAARQRAEQEQMQLERQRAEQEARLLEDTQRRNAERRAAAAAAATGAAGGASTGGTANVPQQDPASQRRPVATDTPQARTNPGGSSRQPTTSQAHPRHGRTASVSQSGQQPYSTAPQAGTAQQPPNTSVQAGQDVASRPRNSFPHAFERWETLSAHWEGLTSFWIRRLEQNNQDIERDPINQALSRQVTDLTAAGANLFHAVVELQRLRASSERKFQRWFFETRAELERAQEVNAMLEAALEEERRARENAVQAAIQKERQHSANDERVKEMKKELQISKEEARRAWEELGRREHEERERTLSLQSGQPTIVGGVQVVPMTQGVPSRHGSSREQRGYQPEYSGQQSGYTGEYSQTPGGQSTAAESEGVTYTGTGSEGGYSEGEYAIDAQGQFIRDSQGNKVPFIAPPSPVSDEGTEEYETPATNPPSAGYAQNPTTAGEQQQQSYGAQDYSGSGYAAPGWETVPRHHHPTRLSDVMEEDERSRASNSQVGARH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPH1</accession>
    <name>E3QPH1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_07903</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697364">
        <property type="protein sequence ID" value="EFQ32759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096779.1">
        <property type="nucleotide sequence ID" value="XM_008098588.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPH1"/>
    <dbReference type="STRING" id="645133.E3QPH1"/>
    <dbReference type="GeneID" id="24413268"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07903"/>
    <dbReference type="eggNOG" id="KOG2495">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021377_8_0_1"/>
    <dbReference type="OrthoDB" id="5376590at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003955">
        <property type="term" value="F:NAD(P)H dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019646">
        <property type="term" value="P:aerobic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051169">
        <property type="entry name" value="NADH-Q_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42913:SF3">
        <property type="entry name" value="64 KDA MITOCHONDRIAL NADH DEHYDROGENASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42913">
        <property type="entry name" value="APOPTOSIS-INDUCING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="6">
        <location>
            <begin position="4"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ32759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="409" mass="43747" checksum="FF2497A088473383" modified="2011-01-11" version="1">MSSTIVIIGAGFAGVWSALSAKRLLNLNNQGGIIDIIVIAPEPYLVMRPRLYEPNASGFKHPLVALFEAVGVRFIQGTAETIDTQAHIVHVRYPAGVESAVPFDRLILAAGSSVVRPQSVDGLQQHAFDIDSLESAAKFEAHLEGLPSRPSSLARNTIVVCGAGFTGIELVAEIPKRLKHLTNLRIILVEGADQIGPELGPGPRPVITEALESLAIEVRLGSAVAAVDSESVTLISGERIETLTVIWTAGVRATPLTHQIPGAKDKLSRIHVDHHLRSLSSDHVFVTGDAAYASADDKGHHALMSCQHALQLGRVSGYNAAADLISKPLLKYSQEAYRCCLDLGSWGAVVTGGWERKVDMQGDSAKRVKGYINQKLIYPPSDAQEALEAADPARPDSDELLKQVITVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPH5</accession>
    <name>E3QPH5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Homoserine O-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_07907</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. MetX family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697364">
        <property type="protein sequence ID" value="EFQ32763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096783.1">
        <property type="nucleotide sequence ID" value="XM_008098592.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPH5"/>
    <dbReference type="STRING" id="645133.E3QPH5"/>
    <dbReference type="GeneID" id="24413272"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07907"/>
    <dbReference type="eggNOG" id="ENOG502QR3J">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028760_7_0_1"/>
    <dbReference type="OrthoDB" id="444135at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004414">
        <property type="term" value="F:homoserine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009001">
        <property type="term" value="F:serine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009092">
        <property type="term" value="P:homoserine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00296">
        <property type="entry name" value="MetX_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008220">
        <property type="entry name" value="HAT_MetX-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01392">
        <property type="entry name" value="homoserO_Ac_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001209">
        <property type="entry name" value="PRK00175.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268">
        <property type="entry name" value="HOMOSERINE O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268:SF16">
        <property type="entry name" value="SERINE O-SUCCINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000443">
        <property type="entry name" value="Homoser_Ac_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="136"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="14"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="417"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="40"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="423"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ32763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="519" mass="56855" checksum="FDF21701531382F5" modified="2011-01-11" version="1">MKCQRLASVALRQARAPVSRVQVPSAYRNPNNAAATHLGSRQHARRFTSKPARKASNSPGDASNPAMAFPCLDALENRSATLEARYESSGPEPSYTAGATETYHCKDPLLLDWGGVLPEFEIAYEYWGKMNADGSNVILLHTGLSASSHAHSTESNPKPGWWEKFIGPGLALDTDKYHVICTNVIGGCYGSTGPSSIDPADGQRYATRFPILTMEDMVRAQFRLLDGLGVDKLYASVGSSMGGMQSLAAGVLFPNRVGRIVSISGCARSHPYSIAMRHTQRQVLMMDPNWNRGFYYGRVPPHAGMKLAREIATVTYRSGPEWEQRFGRRRADPSKPPALCPDFLIETYLDHAGEKFCLTYDPNSLLYVSKAMDLFDLGRENQMAASARRAERAKLMQSGVGPTRNDAACSLTLPEKPYEEQPESNGGASDQPSEVSSRPPEDLIAGLAPLRDIPALVIGVASDILFPAWQQREVAEALKLAGNRNVAHFELSEEMSFFGHDTFLLDLKNIGGNIKNFLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQ43</accession>
    <name>E3QQ43_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Vacuolar sorting protein 39 domain 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_08125</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the VAM6/VPS39 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697366">
        <property type="protein sequence ID" value="EFQ32981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097001.1">
        <property type="nucleotide sequence ID" value="XM_008098810.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQ43"/>
    <dbReference type="STRING" id="645133.E3QQ43"/>
    <dbReference type="GeneID" id="24413490"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08125"/>
    <dbReference type="eggNOG" id="KOG2063">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004190_1_1_1"/>
    <dbReference type="OrthoDB" id="10260443at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034058">
        <property type="term" value="P:endosomal vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000547">
        <property type="entry name" value="Clathrin_H-chain/VPS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001180">
        <property type="entry name" value="CNH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032914">
        <property type="entry name" value="Vam6/VPS39/TRAP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019452">
        <property type="entry name" value="VPS39/TGF_beta_rcpt-assoc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019453">
        <property type="entry name" value="VPS39/TGFA1_Znf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12894">
        <property type="entry name" value="CNH DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12894:SF49">
        <property type="entry name" value="VAM6_VPS39-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00780">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10366">
        <property type="entry name" value="Vps39_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10367">
        <property type="entry name" value="zf-Vps39_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50236">
        <property type="entry name" value="CHCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50219">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CNH" evidence="6">
        <location>
            <begin position="18"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="4">
        <location>
            <begin position="741"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="49"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="456"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="878"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="54"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="70"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="479"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="886"/>
            <end position="898"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ32981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1067" mass="117733" checksum="B161DA9F4A08E291" modified="2011-01-11" version="1">MLSAFTARPIIELKPGVKSKIETILAHGDRVFVGLNNGVLRIYRVNELPPPSPTKANGSQPTATSPPKAIDGDEPPKQIEKPTDLLREIEKFSNRAIEQLAIIKEANTLVSLSNYYVSLHDLGTYEPLEMLSRTKNATCFAVTSNIVKDASTGIPEIISRLAVAVRRRLLLWSWHASELGTDVEEVTLPESIRTVTWASATKIVCGMNAGYVMVDVITHEVEDINSPSSVASGGQVSRFGAVSSAGMGYMGLGGYMPKPLATKLAEGELLLAKDVNSMFITDEGKPIERRQIPWQSAPEQIGYSYPYILALQAPSKGSLEVRNPETLHLLQTISLPGAAQLHFLPPNLSLAHAGKGFHISSDRCVWKMGSTDYDSQIDELVEKGKYDEAVSILNMLEDALLQNKKETLREVKMLKAEALFKQKKYYDSMDLFNEDDVHAPPERVLKLFPPSIAGEMSGWAHGVQPEESGSDGKEDEGESQEKTNGERSVKEDTDANPTSPAKGGVGFAKLFMGHRKPAQPDTASITSKKDPVDVEEASSHRNKPAENQPLEGDDLRDAVRSLAGYLVGTRTRLQRIIDPSTGKLKRSDTNGSTEEAMKSFMSGSHLDESSSQLEGEILRTSRIVDTALFRSYMMTSPSLASPLFRLPNFCDPDVVNEALLAHSRYNELVDFFSGKKLHSQALELLKRFGTAQEPDEAAPGLHGPQRTVTYLQALPPSEIDLILQYSEWVLRADPKLAMEIFIADSENAETLPRGRVARFLGGIDLSLEVQYLEHIISELDESTPEFHDRLVGLFIKQLKDKKRDDEWDAEMGRFVQFLQTSSQYGLTKAFSLIPRDDPAFYEAQAIVLSSVGSHKQALEIYVFKMKNYAKAEEYCNQVHKSKDSRPSSPDQSRRPSSSGDAEDPSPSIYHTLLSLYLTPPPPHKPANEPALELLSRHGSRLPAASTLSLIPDDLPVRDLESYFRGRIRSANSVVNESRIVARLRDTELVSTQALLLLGDNTPGGQGGRNRRVVITEERLCGVCHKRLGGSVVSVLPDNNVVHYACLNKASSQRPQSSRAGTWARRFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQ61</accession>
    <name>E3QQ61_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA(Ile)-lysidine synthetase</fullName>
            <ecNumber evidence="1">6.3.4.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_08143</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>cytidine(34) in tRNA(Ile2) + L-lysine + ATP = lysidine(34) in tRNA(Ile2) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:43744"/>
            <dbReference type="Rhea" id="RHEA-COMP:10625"/>
            <dbReference type="Rhea" id="RHEA-COMP:10670"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:83665"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.4.19"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="6.3.4.19" evidence="1"/>
    <dbReference type="EMBL" id="GG697366">
        <property type="protein sequence ID" value="EFQ32999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097019.1">
        <property type="nucleotide sequence ID" value="XM_008098828.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQ61"/>
    <dbReference type="STRING" id="645133.E3QQ61"/>
    <dbReference type="GeneID" id="24413508"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08143"/>
    <dbReference type="eggNOG" id="ENOG502QQNE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015599_0_0_1"/>
    <dbReference type="OrthoDB" id="434144at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032267">
        <property type="term" value="F:tRNA(Ile)-lysidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01992">
        <property type="entry name" value="TilS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01161">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012094">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012795">
        <property type="entry name" value="tRNA_Ile_lys_synt_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43033">
        <property type="entry name" value="TRNA(ILE)-LYSIDINE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43033:SF1">
        <property type="entry name" value="TRNA(ILE)-LYSIDINE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal" evidence="8">
        <location>
            <begin position="68"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal" evidence="8">
        <location>
            <begin position="324"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="568"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="663"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="663"/>
            <end position="677"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ32999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="842" mass="93035" checksum="D6F727F09B5C9DD1" modified="2011-01-11" version="1">MGLTNPSPLATAAASAAAASATAAAAAATRQYLHPTPKPVSLIEFTDALRAAAPPRFPHARTSQPRRIGLAVSGGVDSMALAYLFNRLREVNPLVRVVDNPLTKISALVVDHGLRPGSDAEAQGVARELRTLRYLRAHIDRVNWRAEGVEGDPAALPNLESAARRARYRRLGIFCAALHIESLFLAHHQDDQHETVLMRLLAGHGSRGLRGISPAANIPECYDMHGVYESGHVDDQMMPIPHVSFRPHKKDWKSMRMELRSELDMDLYAAELRAGLQVDWHESPYVGGGTATDALSRAASSASARARAAAAAAAARNMPRISVEDAGVMIYRPLLGFGKDRLVATCEANNVRWFEDSTNKDRTLTMRNAVRHMVREHALPAALRKDNVLRLAARCDARVRGQEHEADRWLRRYSDAEFEPNVGTLAVRLPDMGVPGGGGRAAARGTRTRTRTRKSVYDDARRELRLAHRRLIAALIVRRLVAFVSPDRNPPQLSSLQTVVGRLFPALADPSDPATPPKAFNQASVLFLPVAPGRWYLVREPYPSLHPPPEMDFYTAKNLDDQRYPIFPPIKRDRPPAEAADAEDAGGDGDKPAEARVVADKERIAQLHRQPLPSHEFKSRRWYSWRRFRLWDGRFWVRVRGRVKAVFRVAPFAPIHAKAFREALGPGQSPPAAGGADADADADTPSNIRPEESAYGGSSSVTGDDGDDARARLEGMLKRFAPGKVRYTLPALYAVNRDEETGEEMLRMLALPTLGVCLPGLERWVQYEFRYRKVDMGLLDGIARGGDSGSSSRTGERTPRAAAVLRKRALEEGKAEERVRRRLNGVRRERLRGARAKTRVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQ69</accession>
    <name>E3QQ69_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08151</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697366">
        <property type="protein sequence ID" value="EFQ33007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097027.1">
        <property type="nucleotide sequence ID" value="XM_008098836.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQ69"/>
    <dbReference type="GeneID" id="24413516"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08151"/>
    <dbReference type="eggNOG" id="ENOG502SQZW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025581_0_0_1"/>
    <dbReference type="OrthoDB" id="3200163at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="68"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ33007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="233" mass="26686" checksum="7ED9333E226DC357" modified="2011-01-11" version="1">MAEVFGVVLKKLWDEVQDVPNEISRLVRQLELPRPVLAEMESEFTQQTHKVYHNSAASLSMEYCQQAVAELDALAEDLRSRIDAAKRSRRNITKLKAALKKEQIQGYQEKMQFALSLLSLSQQTHTISVVKSRFLAFRNPAPQARVQLPSWISETFWDFQAYRACTGWKVSLKPWTMRQTNDPIFIDVRSGSLDDVQKALKCNEASLQDIDEQGWTLLHVRALPIKALESGIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQI1</accession>
    <name>E3QQI1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08263</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697367">
        <property type="protein sequence ID" value="EFQ33119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097139.1">
        <property type="nucleotide sequence ID" value="XM_008098948.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQI1"/>
    <dbReference type="GeneID" id="24413628"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08263"/>
    <dbReference type="eggNOG" id="ENOG502SPD0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_117282_0_0_1"/>
    <dbReference type="OrthoDB" id="5352317at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178738" description="Small secreted protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ33119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="146" mass="15612" checksum="EC8DE1570340AD38" modified="2011-01-11" version="1">MQITNIFLPVLAAATAVSGSPIAKREVKSMMAYGVAEWTIESFVRTCNPENTACDYSFTINTHTTDPTACKFTTTGSPASRAPSNAKCGVYTVTSGWSGQFGDNAGFTTLSVTDQKLIVWPAYTDKQLSNGQVVSPDQSYAPQNLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQK5</accession>
    <name>E3QQK5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA-directed RNA polymerases I, II, and III subunit RPABC3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_08287</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the eukaryotic RPB8 RNA polymerase subunit family.</text>
    </comment>
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        <property type="protein sequence ID" value="EFQ33143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008098972.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQK5"/>
    <dbReference type="STRING" id="645133.E3QQK5"/>
    <dbReference type="GeneID" id="24413652"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08287"/>
    <dbReference type="eggNOG" id="KOG3400">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103864_1_1_1"/>
    <dbReference type="OrthoDB" id="20018at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003968">
        <property type="term" value="F:RNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006363">
        <property type="term" value="P:termination of RNA polymerase I transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006386">
        <property type="term" value="P:termination of RNA polymerase III transcription"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006362">
        <property type="term" value="P:transcription elongation by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006361">
        <property type="term" value="P:transcription initiation at RNA polymerase I promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006384">
        <property type="term" value="P:transcription initiation at RNA polymerase III promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000191">
        <property type="entry name" value="DNA-directed RNA polymerases I, II, and III subunit RPABC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005570">
        <property type="entry name" value="RPABC3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10917">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10917:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03870">
        <property type="entry name" value="RNA_pol_Rpb8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000779">
        <property type="entry name" value="RNA_pol_Rpb8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00658">
        <property type="entry name" value="RPOL8c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ33143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="150" mass="16848" checksum="6EBEBF50E77FA002" modified="2011-01-11" version="1">MSGSGDVTLFEESFTVTNYDQSKYDRVARISATSTDNQTLMTLDINIELFPTSVSDSLHVVLATSLAHDGSKDDEKGWRDVTKGNQDREPTLADMFDYVCYGKIYKFEDADDGQTIKAYVSFGGLLMSLEGPYKKLTPLRVDYVYLLIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRR9</accession>
    <name>E3QRR9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DRBM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08836</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697371">
        <property type="protein sequence ID" value="EFQ33557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097577.1">
        <property type="nucleotide sequence ID" value="XM_008099386.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRR9"/>
    <dbReference type="GeneID" id="24414201"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08836"/>
    <dbReference type="eggNOG" id="ENOG502S8ZQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131085_1_0_1"/>
    <dbReference type="OrthoDB" id="5418749at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00048">
        <property type="entry name" value="DSRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42030">
        <property type="entry name" value="DRBM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42030:SF1">
        <property type="entry name" value="DRBM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ33557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="107" mass="11816" checksum="39D3C5C1107E0F36" modified="2011-01-11" version="1">MYSNKSYSTSAAMSSSYNSQGGTWQERLEDACRDANILPPVFQIVSDRRGGRTAWSSRVTVHGRTLSARFWYDGKNLNNAKEDAAEMALNYLTGSNPSSPANSRGSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QS02</accession>
    <name>E3QS02_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Flavin containing amine oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_08569</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697372">
        <property type="protein sequence ID" value="EFQ33640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097660.1">
        <property type="nucleotide sequence ID" value="XM_008099469.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QS02"/>
    <dbReference type="STRING" id="645133.E3QS02"/>
    <dbReference type="GeneID" id="24413934"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08569"/>
    <dbReference type="eggNOG" id="KOG0685">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004498_8_2_1"/>
    <dbReference type="OrthoDB" id="7777654at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001716">
        <property type="term" value="F:L-amino-acid oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009063">
        <property type="term" value="P:amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.660.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050281">
        <property type="entry name" value="Flavin_monoamine_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742:SF382">
        <property type="entry name" value="AMINE OXIDASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742">
        <property type="entry name" value="FLAVIN MONOAMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180869" evidence="1">
        <location>
            <begin position="20"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="domain" description="Amine oxidase" evidence="2">
        <location>
            <begin position="170"/>
            <end position="651"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ33640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="677" mass="75455" checksum="1951C9EE7714B7B5" modified="2011-01-11" version="1">MARWILSFVAGSALAAASGLPMKLETRSAVSSRVANVHIGLEKPVNETVTFTYGSCRGVSRDDAHHTISETEVRDSQRLVWVLPEDASSDQCISAWGVSGKLLGRSEPQTLHHKWKRRVQKRSIQMNNDTGIDTLGPWFEGVNLLKDKEPGVVDVDAAKSKHVAIVGAGMSGLMSYLVLSQAGMTNISIIEAGQRLGGRVHTEYLTGGPFDYSYQEMGPMRFPEHYRDPKTNTTYNITDHQLVFQLAAEMNELNNHDKNLSVDFIPWIQSNMNGLSYKNGIKLANGLPPTLAQIAANSSLAVASVNDESTNTLSEELDKYLPGSDFSVRMATNMFKAHREFLDSGLKGLGGDVWSEFGFMVNYLKGSLNSTDALGYYSDSSFWDSLYEGMYFEAASWRTIDGGLSRLPSSFHPHVDNITTMNRKIERIQFDSENSRVNLQWRASFKNQTFESASYDYALLAVPFSIIRKWRLPSLPMTISNAIEELPYTSACKVALEFSERFWEHYENPIIGSCSTTSDIPAIGSTCYPSYNINGTGPATMLASYVSGDWGNRWASVSEEEHVQNVLDAMVEIHGENTRDLFTGKYNRRCWVLDPLESASWASPVAGQHQLYIPEYFKTYDNMIFIGEHTSYTHAWIASALESGIRGSVQLLLELGLVDEAKAAVNKWMARWIDIVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QS87</accession>
    <name>E3QS87_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hydantoinase/oxoprolinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_08858</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697373">
        <property type="protein sequence ID" value="EFQ33714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097734.1">
        <property type="nucleotide sequence ID" value="XM_008099543.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QS87"/>
    <dbReference type="STRING" id="645133.E3QS87"/>
    <dbReference type="GeneID" id="24414223"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08858"/>
    <dbReference type="eggNOG" id="ENOG502QQBE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_776139_0_0_1"/>
    <dbReference type="OrthoDB" id="5404895at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008040">
        <property type="entry name" value="Hydant_A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002821">
        <property type="entry name" value="Hydantoinase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045079">
        <property type="entry name" value="Oxoprolinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365">
        <property type="entry name" value="5-OXOPROLINASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365:SF10">
        <property type="entry name" value="HYDANTOINASE_OXOPROLINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05378">
        <property type="entry name" value="Hydant_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01968">
        <property type="entry name" value="Hydantoinase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydantoinase/oxoprolinase N-terminal" evidence="2">
        <location>
            <begin position="3"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Hydantoinase A/oxoprolinase" evidence="1">
        <location>
            <begin position="144"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ33714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="357" mass="37845" checksum="38829426046C621E" modified="2011-01-11" version="1">MAPSQVSSVKIGTTQFVNAVLEQNKSKLDKVAVIRLCGPYSRRSPPFVGFPVGLCDLMEGHYGYVDGGYQVDGRVVRTLRHEQLKEQAAIIKSQSIKSLVVVGVYSPSNPEQELEAASVLVSELGAGYDVSCSHKVGRLGFLERENASILNASLRRFARHVIAGFKIAAQKLGKCSLHITLNDGTLSKASEAAEHPVRCFSSGPTNSARGAALLAGSLSHTDDRETLVIDIGGTTTDICGLLKTGFPRQSPAFVNIAGVRTNLTIPDVHSIAATDLILSNDRTDRLVQSHAKASGLAEINRAVEEAIDLVKTKPGDVRAILVGGGSIIISDEIAGVGELIRPEYLEVANAVGAAWLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSY9</accession>
    <name>E3QSY9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1996 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_09121</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697375">
        <property type="protein sequence ID" value="EFQ33977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097997.1">
        <property type="nucleotide sequence ID" value="XM_008099806.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSY9"/>
    <dbReference type="STRING" id="645133.E3QSY9"/>
    <dbReference type="GeneID" id="24414486"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09121"/>
    <dbReference type="eggNOG" id="ENOG502RX74">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044729_0_0_1"/>
    <dbReference type="OrthoDB" id="74764at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018535">
        <property type="entry name" value="DUF1996"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662:SF12">
        <property type="entry name" value="DUF1996 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09362">
        <property type="entry name" value="DUF1996"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1996" evidence="3">
        <location>
            <begin position="22"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ33977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="256" mass="27535" checksum="18E838A735C808EC" modified="2011-01-11" version="1">MILLIFNGFFIIGSLVIGHFALYTTDGGKTYTPMPVSRFSAYYNLGETPAEVAIPQNLKMVAGDAEALTQDAMITEAQSSWGCENGEGESLDANGFPSTTCGTHVHQLLFFPQCVNTETLETTYKDRRGGTCPSGMKSMPQLRFSIRYDVRKVLPNGWTGTAPFKLSCGPAWCSHGDFINGWTEEAATNMIATTEEKMKFSAVSGALGDAGSGPTCKAKDADPSHGTGDYAKSVAVMSKRDVDSSGWSSKSRYVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QT41</accession>
    <name>E3QT41_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Oligopeptide transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_09173</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697375">
        <property type="protein sequence ID" value="EFQ34029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098049.1">
        <property type="nucleotide sequence ID" value="XM_008099858.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QT41"/>
    <dbReference type="STRING" id="645133.E3QT41"/>
    <dbReference type="GeneID" id="24414538"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09173"/>
    <dbReference type="eggNOG" id="ENOG502QUDW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010539_1_0_1"/>
    <dbReference type="OrthoDB" id="77405at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045035">
        <property type="entry name" value="YSL-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31645:SF3">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31645">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER YGL114W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="289"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="316"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="407"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="450"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ34029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="497" mass="54512" checksum="9ACC41D3F5EE2C1E" modified="2011-01-11" version="1">MYRLGLMDSTPSGDIGKIFTLTICCSFFGIFFVTPLRKFFIIRTARELKLMFPTPTAAALTIRSMHAGIKGAQEAASKLKALGLAFFACIGHRVASYYAIGILYDWHVFTWIHIWSGHTSWAMNIESWGWHFEWTTAFIGSGMLIGMNSACSMMAGSVLAWGLIGPVLVHYGECIGLDASDGDPKWNGYYSFTSLKNVGSGPPSPRYWLLWPGVMVMVCSSMAELLVHWKIIYYGFKAGWKSICLSVHQTAMKRNKRIEFFAKYAEAEEKMDANHVEDPATPDQQVNTWIWVTGLFASIILACIVMGVQWHVNVGVTMLALVLAFLFSFLAIQIGAVTDQTPLTAAAKAAQLVIGGTTTGAGYTVQYAQRINLISAGLAAGAADVATALTSDFRTGFLLGTPPKKQFIAQAIGTFVSVWLAPGLFVLFTSGYPFAEVVTSPDVPIPLSSGIFSIILSVFSILQVIFRYYYLTGSREKYQQWLPNWGAIALSFVIPGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTA5</accession>
    <name>E3QTA5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_09237</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697376">
        <property type="protein sequence ID" value="EFQ34093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098113.1">
        <property type="nucleotide sequence ID" value="XM_008099922.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTA5"/>
    <dbReference type="STRING" id="645133.E3QTA5"/>
    <dbReference type="GeneID" id="24414602"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09237"/>
    <dbReference type="eggNOG" id="ENOG502SSB8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046870_5_1_1"/>
    <dbReference type="OrthoDB" id="444631at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF162">
        <property type="entry name" value="SATRATOXIN BIOSYNTHESIS SC1 CLUSTER PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="23"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="225"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="41"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="352"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ34093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="380" mass="42174" checksum="7B6F7C94409CC4B0" modified="2011-01-11" version="1">MSAAASPDAPLAAGAAQSVDPRTLAAIIWTCFSVATLFAALRLTVRWRQNRHFLADDYCIILAWMCLVTMASLQTRQLDALYYTTYLVAGRIPVTAETAARLEDLARWQYPIIKLFWTVLWSVKASFMAVFYPLVKTLPVRRGLWYCVAVFALLAYIGCWVASTLTCSPPSDYFRAGKCNKPHEVWMQTFNVLYSTSVDVVSDMMIMALPLTILPSLQIDGKKKIGLAVAFSLASIIICVAIVRMTHVIKGQHVDLVGLAIWGAVETATAVVVGSLLPLKALLTRGVKKYHSSASKSNTQRYGIHQNQPGDAITYVPDMTSRSVMVTQSIPLDDLHRSRQMNGRIYVQRTYETHASRDDSSREDDDEVAIVKSQAKGWEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTJ4</accession>
    <name>E3QTJ4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ubiquitin-conjugating enzyme E2-16 kDa</fullName>
            <ecNumber evidence="1">2.3.2.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">E2 ubiquitin-conjugating enzyme 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Ubiquitin carrier protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Ubiquitin-protein ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_09326</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="11">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="1"/>
    <dbReference type="EMBL" id="GG697377">
        <property type="protein sequence ID" value="EFQ34182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098202.1">
        <property type="nucleotide sequence ID" value="XM_008100011.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTJ4"/>
    <dbReference type="SMR" id="E3QTJ4"/>
    <dbReference type="STRING" id="645133.E3QTJ4"/>
    <dbReference type="GeneID" id="24414691"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09326"/>
    <dbReference type="eggNOG" id="KOG0417">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030988_13_3_1"/>
    <dbReference type="OrthoDB" id="7851174at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045842">
        <property type="term" value="P:positive regulation of mitotic metaphase/anaphase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032933">
        <property type="term" value="P:SREBP signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd23792">
        <property type="entry name" value="UBCc_UBE2D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000010">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2-16 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 11" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="12">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="10">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00074661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00077197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ34182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="147" mass="16480" checksum="2C1877D34F37D955" modified="2011-01-11" version="1">MALKRINKELTDLGRDPPSSCSAGPVGEDLFHWQATIMGPGDSPYSGGVFFLAIHFPTDYPFKPPKVNFTTRIYHPNINSNGSICLDILRDQWSPALTISKVLLSICSMLTDPNPDDPLVPEIAHVYKTDRARYEATAREWTRKYAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTL7</accession>
    <name>E3QTL7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Tat pathway signal sequence</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_09436</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Mycotoxin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ustYa family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697378">
        <property type="protein sequence ID" value="EFQ34292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098312.1">
        <property type="nucleotide sequence ID" value="XM_008100121.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTL7"/>
    <dbReference type="STRING" id="645133.E3QTL7"/>
    <dbReference type="GeneID" id="24414801"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09436"/>
    <dbReference type="HOGENOM" id="CLU_042941_4_2_1"/>
    <dbReference type="OrthoDB" id="3687641at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043386">
        <property type="term" value="P:mycotoxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365:SF11">
        <property type="entry name" value="TAT PATHWAY SIGNAL SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365">
        <property type="entry name" value="YALI0B05434P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ34292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="183" mass="20675" checksum="6647457E2448F6D3" modified="2011-01-11" version="1">MFVVAILRTPSSQPQPSLYWEEPVRSEILLKNKPRTFTLDVDYAMPPSETVNEAWSSLLPKQGGFFKHPTISPSESCFAVFHQIHCLDMLRLALYELHPDTRNSSHHAGHGSHKYHSTAAEANASNDIYHVGHCFDLLRQTIMCRPDLTAEPINPALGGVTGFGTERQCIDWRELMDWMAANE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTM4</accession>
    <name>E3QTM4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09443</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697378">
        <property type="protein sequence ID" value="EFQ34299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098319.1">
        <property type="nucleotide sequence ID" value="XM_008100128.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTM4"/>
    <dbReference type="GeneID" id="24414808"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09443"/>
    <dbReference type="eggNOG" id="ENOG502R9QU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1510486_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="178" mass="19645" checksum="0E5E15AA86926C0C" modified="2011-01-11" version="1">MKNDQRLSSGSSLQRPTFSAADLITSTSPSGSALLSPSLTTEPQSPTQNVCLPLSPLESPSLEKHGQRYEMFSFRVEGAYDAVLSQLDSKRFRRSKKSRRRFDIEVQKASCLNTIGCLVRVLVSQPLEATSSQDASIEVCTLIDDALNNLWIQLSYLARDITRFGQKHEIVSGPPIVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUH1</accession>
    <name>E3QUH1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_09653</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697381">
        <property type="protein sequence ID" value="EFQ34509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098529.1">
        <property type="nucleotide sequence ID" value="XM_008100338.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUH1"/>
    <dbReference type="STRING" id="645133.E3QUH1"/>
    <dbReference type="GeneID" id="24415018"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09653"/>
    <dbReference type="eggNOG" id="ENOG502RUUF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019101_1_0_1"/>
    <dbReference type="OrthoDB" id="3903189at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF166">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="22"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ34509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="365" mass="42003" checksum="7A75ED444CF5FA6D" modified="2011-01-11" version="1">MDDPTIFIHWFSSLLAFSIMMVRLTWKKIAKQEFNVGDWFTLAAIVCVMTRLGLIHVVLTWGTNNVSASYRKTHMFTDEEIYRREIGSKLSIVNRVFYNSYLWLQKLVLLDVYRRLMSTIRQETFVMWFYGVVFFGTYAACQVTTFSECNPFHLYWQVIPDPGSCAKAQMQLVVVGVLNIITDFMLLILPLPLVFSLKTPWQRKLQLYILFTLGIFIIAITVIRLPINVTNKDSQVNRTTWASTELLTAAIVVNAPTLYGLWNKTRKAKSTVKTSGYPSGLNHYGGESNVLTSHRSTVIRTNQDESFLMNSRHKMGHMDGIIQTKEVIVSEFRQEADRKGRNYIHLSDDMENVTSHSSNHGMLTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVW8</accession>
    <name>E3QVW8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_10150</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="GG697386">
        <property type="protein sequence ID" value="EFQ35006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099026.1">
        <property type="nucleotide sequence ID" value="XM_008100835.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVW8"/>
    <dbReference type="STRING" id="645133.E3QVW8"/>
    <dbReference type="GeneID" id="24415515"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10150"/>
    <dbReference type="eggNOG" id="KOG1164">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019279_2_7_1"/>
    <dbReference type="OrthoDB" id="5800476at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14125">
        <property type="entry name" value="STKc_CK1_delta_epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000159">
        <property type="entry name" value="Casein kinase I hhp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000538">
        <property type="entry name" value="Putative Casein kinase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050235">
        <property type="entry name" value="CK1_Ser-Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11909">
        <property type="entry name" value="CASEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="9"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="306"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="319"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ35006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="390" mass="44084" checksum="5BBD70EB92E0201B" modified="2011-01-11" version="1">MDLRVGNKYRIGRKIGSGSFGDIYLGTNIISGEEIAIKLESVKAKHPQLEYEARVYKSLAGGVGIPFVRWFGTECDYNAMVLDLLGPSLEDLFNFCNRKFSLKTVLLLADQLISRIEYIHAKSFIHRDIKPDNFLMGIGKRGNQVNVIDFGLAKKYRDPKTHFHIPYRENKNLTGTARYASINTHLGVEQSRRDDMESLGYVMLYFCRGSLPWQGLKAATKKQKYDRIMEKKMTTPTEVLCRGFPNEFAIYLNYTRSLRFDDKPDYSYLRKIFRDLFVREGFQYDYVFDWTVYKYQKNAQAIAQAAGATQEEDEKARASRTNAATAGQPTPQSGANKPNALPSSRRKVIERGSGVDTPDTNRAVGGSDRILRSATKSAGPAYGSSSHLPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>E3QW09</accession>
    <name>E3QW09_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Import receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_10191</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the Tom70 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697387">
        <property type="protein sequence ID" value="EFQ35047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099067.1">
        <property type="nucleotide sequence ID" value="XM_008100876.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QW09"/>
    <dbReference type="STRING" id="645133.E3QW09"/>
    <dbReference type="GeneID" id="24415556"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10191"/>
    <dbReference type="eggNOG" id="KOG0547">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017516_0_1_1"/>
    <dbReference type="OrthoDB" id="2942533at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030943">
        <property type="term" value="F:mitochondrion targeting sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045039">
        <property type="term" value="P:protein insertion into mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005687">
        <property type="entry name" value="Tom70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00990">
        <property type="entry name" value="3a0801s09"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46208">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46208:SF1">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14559">
        <property type="entry name" value="TPR_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 10" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="10">
        <location>
            <begin position="169"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="10">
        <location>
            <begin position="340"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="10">
        <location>
            <begin position="374"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="10">
        <location>
            <begin position="408"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="10">
        <location>
            <begin position="476"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="10">
        <location>
            <begin position="551"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="66"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="81"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="99"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ35047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="624" mass="69211" checksum="3F06868028C92B94" modified="2011-01-11" version="1">MSNPLPSVPPMASPPTVIPVDSSSGLWDRITTWAADNKAVVYTAAGVAVVATGAGVIYFLNSDSKKESTPKLSKKERRKRKEAERKAAETEKQPTSTEAAAPTQPKAAAVESADELPEIDETTVASFTADQRERYAAKLKDVGNQAYGSKDYNKAIELYSKAILCKANPIFYSNRAACYNALGNWDKVVEDTTAAINLDPEYVKALNRRANAYEHLKMYSEALLDFTASCIIDSFKNESSAQAVERLLKKFAEQKAQEMMADRPSKLPSHTFVGNYLQSFRVKPRPAGLEDSAILSEDTGKGQLQLGLRALEKKTGDGYEEARAAFEKALELGELGEFEALAYNLRGTFSCLLGKHDDAMADLSKSIELDPSMTQSYIKRASMNLELGAPEKAAEDFEKAMEHNSEDPDIYYHRAQLHFIKGEFSDAAKDYQKSIDLDRDFIFSHIQLGVTQYKMGSIASSMSTFRRCIKNFKEVPDVYNYYGELLLDQGNFQEAIEKFDSAIDMESKTKPMAMNVLPLINKALTLFQWKQDFGEAEKLCQKALIIDPECDIAVATMAQLLLQQGKVTEALKYFERAAELARTEGEIVNALSYAEATRTQLQVQEKYPKLAAKLQGIGPGGMPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWJ0</accession>
    <name>E3QWJ0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Voltage-dependent potassium channel beta subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_10372</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the shaker potassium channel beta subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697390">
        <property type="protein sequence ID" value="EFQ35228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099248.1">
        <property type="nucleotide sequence ID" value="XM_008101057.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWJ0"/>
    <dbReference type="STRING" id="645133.E3QWJ0"/>
    <dbReference type="GeneID" id="24415737"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10372"/>
    <dbReference type="eggNOG" id="KOG1575">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_0_1"/>
    <dbReference type="OrthoDB" id="1720422at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034220">
        <property type="term" value="P:monoatomic ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005399">
        <property type="entry name" value="K_chnl_volt-dep_bsu_KCNAB-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43150">
        <property type="entry name" value="HYPERKINETIC, ISOFORM M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43150:SF6">
        <property type="entry name" value="VIC POTASSIUM ION CHANNEL, BETA SUBUNIT (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01577">
        <property type="entry name" value="KCNABCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="26"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ35228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="352" mass="39323" checksum="F7AC3A438BAA962E" modified="2011-01-11" version="1">MAWEEPRKTGMQYRRLGNSGLHVSVLGLGGWLTFGGHVENEKTFACMKQAYDLGVNFFDTAESYAGGNSEVIMGQAINKFGWNRNDIVVSTKLNWGGANGEVLVNNHGLSRKHIIEGLRASLKRLNLEYVDIVYAHRPDRLTPMEETVRAFNHVIDKGWAMYWGTSEWSADEIAEACGIAKDLKMIPPVVEQPQYNILERRKVEYEFQRLYQRFGLGLTVFSPIKMGLLSGKYNDNPDAPPAGSRFAEGTGDKFVNWANKEWYGNDEWKAMIQNVVKLKGIAEKLGATQSQLALAWCLKNPNVTSVITGASRPEQIVENVGAVKVLEKLTPEIMAEVDTVVGEVKLDPARQD</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2011-05-31" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWM6</accession>
    <name>LCL3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName>Probable endonuclease LCL3</fullName>
            <ecNumber>3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">LCL3</name>
        <name type="ORF">GLRG_10408</name>
    </gene>
    <organism>
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location>Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the LCL3 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-"/>
    <dbReference type="EMBL" id="GG697390">
        <property type="protein sequence ID" value="EFQ35264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099284.1">
        <property type="nucleotide sequence ID" value="XM_008101093.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWM6"/>
    <dbReference type="SMR" id="E3QWM6"/>
    <dbReference type="STRING" id="645133.E3QWM6"/>
    <dbReference type="EnsemblFungi" id="EFQ35264">
        <property type="protein sequence ID" value="EFQ35264"/>
        <property type="gene ID" value="GLRG_10408"/>
    </dbReference>
    <dbReference type="GeneID" id="24415773"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10408"/>
    <dbReference type="eggNOG" id="ENOG502S1U4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046484_0_1_1"/>
    <dbReference type="OrthoDB" id="430293at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.90:FF:000029">
        <property type="entry name" value="Probable endonuclease lcl3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035437">
        <property type="entry name" value="SNase_OB-fold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016071">
        <property type="entry name" value="Staphylococal_nuclease_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12302">
        <property type="entry name" value="EBNA2 BINDING PROTEIN P100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12302:SF3">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00565">
        <property type="entry name" value="SNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00318">
        <property type="entry name" value="SNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50199">
        <property type="entry name" value="Staphylococcal nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50830">
        <property type="entry name" value="TNASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0106">Calcium</keyword>
    <keyword id="KW-0255">Endonuclease</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0496">Mitochondrion</keyword>
    <keyword id="KW-0540">Nuclease</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <feature type="chain" id="PRO_0000408657" description="Probable endonuclease LCL3">
        <location>
            <begin position="1"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="TNase-like" evidence="3">
        <location>
            <begin position="85"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="252"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="257"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="5"/>
    <sequence length="273" mass="30604" checksum="39C95FD4E4C8FE84" modified="2011-01-11" version="1">MPWPFSSSSSAGSPTHSQKEDGARSKPTSWNDLLPKPDPPLHAAKEWAPVFLTSVASLAAFIFYQSRLRRFPTAGHIQPDLFRKRTLLGRVTSVGDGDNFHMFHTPGGRLAGWDWLRKVPTTKTALKGKTIPVRMAGIDAPEGAHFGRPGQPGAAEALQWLRSYILDKRIWVRIHRRDQYDRVVATVYVRRFLFKKDVGLEMLKLGLATTYEAKSGVEWGGAEEAYKAAEAKAQSKRLGIWNGEASTFESPRAYKTRTNETEGKKSEWFSGWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWP7</accession>
    <name>E3QWP7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_10429</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697390">
        <property type="protein sequence ID" value="EFQ35285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099305.1">
        <property type="nucleotide sequence ID" value="XM_008101114.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWP7"/>
    <dbReference type="GeneID" id="24415794"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10429"/>
    <dbReference type="eggNOG" id="ENOG502SPKB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1402319_0_0_1"/>
    <dbReference type="OrthoDB" id="1896086at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003181029" evidence="2">
        <location>
            <begin position="23"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ35285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="194" mass="20925" checksum="EAA226BEA4E3647D" modified="2011-01-11" version="1">MLIFTLNHSTTAVALIAGLAAGEPAFYVSASARKVSDAPSPTSEASGIPSRTRAPGITPLEAQARICNLEADYSPHDPIDSEKQEKGVSTFCDLLRGKGGYLEPGMESQRVEFQDANGGRHHYKVEWAAGCQTEVENQAIRRPLGHVSASLNCHDLMRDNYLLCHNGGVGGKVQVGCLIYTYNGGIMTGRVYDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>E3QX05</accession>
    <name>E3QX05_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Beta-ketoacyl synthase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_10537</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697392">
        <property type="protein sequence ID" value="EFQ35393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099413.1">
        <property type="nucleotide sequence ID" value="XM_008101222.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QX05"/>
    <dbReference type="GeneID" id="24415902"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10537"/>
    <dbReference type="eggNOG" id="KOG1202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_31_0_1"/>
    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901336">
        <property type="term" value="P:lactone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030639">
        <property type="term" value="P:polyketide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05195">
        <property type="entry name" value="enoyl_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000209">
        <property type="entry name" value="Polyketide synthase Pks12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056501">
        <property type="entry name" value="NAD-bd_HRPKS_sdrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049552">
        <property type="entry name" value="PKS_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF18">
        <property type="entry name" value="ENZYME, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23114">
        <property type="entry name" value="NAD-bd_HRPKS_sdrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21089">
        <property type="entry name" value="PKS_DH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="9">
        <location>
            <begin position="9"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="10">
        <location>
            <begin position="931"/>
            <end position="1237"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="8">
        <location>
            <begin position="2328"/>
            <end position="2404"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="6">
        <location>
            <begin position="931"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="6">
        <location>
            <begin position="1078"/>
            <end position="1237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1405"/>
            <end position="1446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1418"/>
            <end position="1435"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="6">
        <location>
            <position position="963"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="6">
        <location>
            <position position="1143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ35393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="2406" mass="261989" checksum="A8CF975A4CE468AA" modified="2011-01-11" version="1">MSEPTYDSREPIAIVGFACRLPGGNYSPPQFWEFLKRGEIAYNKVPESRFNHAAHYDGSLKPRTMRQPGGMFLKDIDLADFDAKFFELSATEATAMDPAQRQMLEVVYEGLENAGIPLDKVNGQSVGCYVGNYASDYGDMGARDPEDRSPGHGLGIARTILANRISHFLNIHGPSVTLDTACSSSLVGLDLACQALRARSIDTGIVAAANVYMSPEHLIDAGGVGGAHSLTALCHTFDAAADGYVKAEAVNTVIIKRLSDAVRDRDPIRAVVLGTSSNHNGRTMGIASPSADAQAMAIRAAYANAGITDFNKTAFFEFHGTATQAGDAAESQGAASVFSASRSAENPLIIGSVKSNVGHSEPAAGLTGLMKAVLAIENGVIPGNPTFINPSPKIDFVGNKMKATRTLIPWPTDALRRASVNSFGIGGSNAHAIVEAARAEDCSNHVYSYRDKDGDFTLDDDDDDDDKAKQTYTLVLSANDSASLAANIRAFCAHLINPNVKVDLADLAYTLSERRSRLFHRAFVSTKTTDIYENLFTTAKKSPKTPKVGFLFTGQGAQWPRMGKALVDAVPWIRTTLEDMDKILQSLPNPPEWSLVSELMEPRSAEHVRQPDMAQPLVAALQMCLVDVLRSWGIKPSSVLGHSSGEGAAAYAAGWMSRSDCIKCAFYRGQAAKNISDQMERDVGMLALGLGAEAAAPFLEKHRGDAFIACYNSPSSLTISGRLSALDSISEEVKAAGYFARALLVDMAYHTPFMAAAAEGYQKLLDKDQEFGREDGSQSGIAMFSSVTGLKNEMTTGSTYWKNNMISPVRFDAALEEMLKQDSPDMLIEIGPAGALAGPVSQLLKSLANAGNVSYCTAWSRGANASKSLFDVAGHLFATGGDVDLALVNRYNDKKVRTVVDLPNYTWNHDVKYWHESAASKDWRFRKFPVHDLLGSKVLGAPWHTPVWRNRLNASNVPWIMQHKMGGDAIMPAAGYLTIAVEALFQKLRAIDPKECPATPNELCYCFRNVRFQRAMVVEEDKDVRMMVTLNKVPGSDDWHEFRISSTSEEDVTAEHCFGLVRTQDAVDDVAQNLTPPKSTAPVERWYKATRDIGMGFGPVFKRMLQVESTSGVRACRVLLTMEPPASAYSPQSYYPVHPAALDGCFQTPIPANMEGEIVNVRDVMIPTIVDEVVINKVPKQLNNALAEATSVYSGRGRPDQDKSWVASSSVVDSQSGALMVRITGLHYIKLDVPPTPDPHVFDQVTWVPDVSLLTQDQLLHLDPATSGDRLNRIIDLVAYKKPALRVLEVHLDEEDTSCLWFDAENAAYRQAYARYDFVASSSKPLASVSAKHEGKEDSGFSLMRLEEQDLGLESPEPYDLALVKLSKTSVADDVLRIVLPLLSTDACTLVVRGSEENQAVAEQAEITDESEEFEHVTSSATSQTGSAATPLRSSGSDDGKGSSSIDSAILDHEALKIDSTAASIELGDMTQDGRSAYLLSSIGSFLGNKSTTPRTIVVPRLSGGGDSALTASLRSSLESAGWLVEERTAPFQPLAKDEIALVLDELTSPLLRHANQDQWDAIKALVSSGNPVLWVTKGAQSSATDPDHALVYGLFRVARREDQGANLTILDVQSSTGHGMEAALDKVLRLLAQGAMTESEVMEREGILHIQRVVPDVLVNEFKRAETEGMPVVSKSFHGNEVQVQLRAERLGTLEGLTWCETESQEPSILEDHIEVEIMAVGVNFKDVAVTMGVVPDNEYSLGYECAGVVRRLGPAVKKFRVGDRVCMLKQGSHANRIRVHIDRCHVIPETMSYEDAATIPCVYLTSLYALYHLASLQEGQSVLIHSATGGIGIACIELARHKQAEIYVTVGTEEKRQFLEREYGIPRSRMFSSRSTKFAGEIMQETNGRGVDVIVNSLIGELLDASWRILADGGIMVEIGKRDIVNRNTLAMEPFDRNCSFRAVDLSYTKHFNEPIVARLLTELFILINAGHIRPIHPVTTYAFEDVPAALAYIRTGRHLGKIVITNKYDKEILVPTRPAVRPLKLSPDVSYLIVGGLKGLCSTLAVHMAQHGARHIVVSNRSGISDEVSAKVVRDCMSYGCRVTEAKGDIGNAEFVRRLVQNTFPRLGGIVQGAMALNDTSYESMTKDQYRDTIYAKVEGTWNLHNATQELLKQPLDFFTMLSSTSGVAGRVGQANYAAANTFLDAFASWRQRQGLCGNSVNLGLIEDIGYVAEDETGLDAKINRAHWVPIYEGMLRRIFTYSVFQQDRHSPLNKESSAQLVTGIAYPYPQDGSDTSLNPRFSHLCSSRGADRKGASDGGDGGDDIDQGVRNLLSLNKSGVDIATLTKACTDVICLQFARILRLGDAVEPGKSPMSYGLDSLSGVELRNWVRNKLDVTLSTLDIVNATSILALVEKIVAKMLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXG1</accession>
    <name>E3QXG1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DEK C terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_10693</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697395">
        <property type="protein sequence ID" value="EFQ35549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099569.1">
        <property type="nucleotide sequence ID" value="XM_008101378.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXG1"/>
    <dbReference type="STRING" id="645133.E3QXG1"/>
    <dbReference type="GeneID" id="24416058"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10693"/>
    <dbReference type="eggNOG" id="KOG1946">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046065_1_1_1"/>
    <dbReference type="OrthoDB" id="10251073at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10567">
        <property type="entry name" value="SWIB-MDM2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.245.10">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014876">
        <property type="entry name" value="DEK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019835">
        <property type="entry name" value="SWIB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036885">
        <property type="entry name" value="SWIB_MDM2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003121">
        <property type="entry name" value="SWIB_MDM2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13844">
        <property type="entry name" value="SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08766">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02201">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00151">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109715">
        <property type="entry name" value="DEK C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47592">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51998">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51925">
        <property type="entry name" value="SWIB_MDM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180951" evidence="2">
        <location>
            <begin position="22"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="DEK-C" evidence="4">
        <location>
            <begin position="31"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="DM2" evidence="3">
        <location>
            <begin position="209"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ35549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="257" mass="27809" checksum="2883D6EFE9A7D79C" modified="2011-01-11" version="1">MSLPRTVFLSTFGLCCPPSYATANAICAVSSEEENNYTSIIDGILATADLTTITRKKIRLGLEKALGGKDLSDQKHAIKALIEERFDAISGSGDAAPLADSYSASPAPKREANGHDEDDGHGEIQVSVAPARKRQKREDSSEDADAKLAAELQAQENRMARGRTTRGGNGATSKVTKKKKAPRKKSDKKVDDSDVDDSGEPPKRKAGGGFQKPFNLSEPLAELLGESQLSRPQVVKKLWEHIKGNDLQDPDNKRHFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXH3</accession>
    <name>E3QXH3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_10705</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697395">
        <property type="protein sequence ID" value="EFQ35561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008101390.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXH3"/>
    <dbReference type="STRING" id="645133.E3QXH3"/>
    <dbReference type="GeneID" id="24416070"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10705"/>
    <dbReference type="eggNOG" id="KOG0583">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007199_0_0_1"/>
    <dbReference type="OrthoDB" id="942095at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14003">
        <property type="entry name" value="STKc_AMPK-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000434">
        <property type="entry name" value="Serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF110">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="39"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="408"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="541"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="601"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="794"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="347"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="435"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="483"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="573"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="634"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="667"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="687"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="703"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="803"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="828"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="879"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ35561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="895" mass="97325" checksum="A88D72A0EEFB929B" modified="2011-01-11" version="1">MQANRGNAEALGRKAKLARSYQELLDEFSNKDLSSVGNYTLGRLIGKGSFGKVYLATHKLTNGSKVVLKSANKGDSNLAREIHHHRQFVHPHIARLYEVIVTENLVWLVLEYCAGDELYNYLLEHGPLPVHKVQKIFAQLVGAVAYVHQQSCVHRDLKLENILFDKHENVKLVDFGFTREYEGKSNYLQTFCGTICYSAPEMLKGEKYAGEKVDVWSLGVILYALLCGELPFDDDDDNVTRTKILNEEPKYPDHLPPAAIPLIQSLLSKRPLLRPSLPDILTNPFLAEHTPAQQAILKLQRPAPFSTPLEKETLQRMRSAGVAIDSVIESVLAQRCDALAGWWTLLIEKEQRKVRRRERKRREREAENRSLRRLSAASSRLERIAPVLQEVDEHGGLTNRFIRLEDAPITPRTRGRSERRSAHYSDFGDLPGLPEHAKENGGPGTDEHPPPPIDKDSVRSASTSGHGRPVPPPKEGVVRSARSRGSTLHLVTTSEALAANRTPERPPDQQQKVRKKPSQAIIAHWKHWTHWFFENTRRTRHASKRGSHSTPSLVDKNGSVAGNSSKHSKDSSPRPQTGKNPMTDNSVAQAKAGLPRGVVANGHLNKALPGHRGSGAFSSPGSGGGSTPSQMPSRISTSYKRQSLSPSPMTPRTTMRRSSAGLRGRKSTSSSVSSIRSMPHHHHSHSKASSTSSNGSVSTSISKNTLQRGQSPHHSVKVLPATPTSTTFPSNIRLVRGPGPPAPLALFTEGMPPPPVSGAQAPGSPNPFAQGGGIQFAKRKRNIFKGPMLTFGGGGAGGGGSGARSTGSSHSRSASASGMGRRSGEVTIQEEEEGEEDEEEIEEVDVFTPVVGGPGERIEEQIIEDGETDAVGAQAKADTSAAPVTPKTTAPPAHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXJ3</accession>
    <name>E3QXJ3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Splicing factor 3a</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_10725</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SF3A3 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697396">
        <property type="protein sequence ID" value="EFQ35581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099601.1">
        <property type="nucleotide sequence ID" value="XM_008101410.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXJ3"/>
    <dbReference type="STRING" id="645133.E3QXJ3"/>
    <dbReference type="GeneID" id="24416090"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10725"/>
    <dbReference type="eggNOG" id="KOG2636">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027160_1_0_1"/>
    <dbReference type="OrthoDB" id="2160351at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000690">
        <property type="entry name" value="Matrin/U1-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051421">
        <property type="entry name" value="RNA_Proc_DNA_Dmg_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031774">
        <property type="entry name" value="SF3A3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024598">
        <property type="entry name" value="SF3a60/Prp9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021966">
        <property type="entry name" value="SF3a60_bindingd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12786:SF2">
        <property type="entry name" value="SPLICING FACTOR 3A SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12786">
        <property type="entry name" value="SPLICING FACTOR SF3A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16837">
        <property type="entry name" value="SF3A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12108">
        <property type="entry name" value="SF3a60_bindingd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11931">
        <property type="entry name" value="SF3a60_Prp9_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12874">
        <property type="entry name" value="zf-met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50171">
        <property type="entry name" value="ZF_MATRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Matrin-type" evidence="9">
        <location>
            <begin position="418"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="363"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="375"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ35581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="513" mass="59135" checksum="D96CCE4CB2470667" modified="2011-01-11" version="1">MGVIEEQRYLHEDLERLEQGIADRISEEPKHIRDRLNRDHEIAQLLDQIQAQSVKLLDIYHDADGDRSREIQSIGTGDPFEEFYSQVKDVREHHAKYPNEQAENSEVRYRVKKPDDGEIMPYIVDRLFTGEEGFGRFFDLHTCHESYLNLPNVKRLSYLQYLEVFDNFIPGHGGLKRADKLTDQYFKYVGELAEYLESFMRRTRPLENLDKVFLGFDNDFEAAWDKDEVPGWQKEDGANSTTREPSTADAIWCDDCEKEFKNENVYRSHMTGRKHIKAAEARKARLDEGAGDGTNGNTNGHRVSATRLKERAVAEREYRVKRLAAAMSTERGDTRVNVERRQGMTERERQQELENIMNLSYSAPGGGGMHGGADHDDDDGDGEDGEEKIYNPLKLPLAWDGKPIPFWLYRLHGLGVEFPCEICGNFVYMGRRAFDKHFNEARHVHGLRCLGVTNTTLFRDITSIEEAVNLWDKIQREAKKSKVDEGSVVQMEDAEGNVMPEKVYYDLQKQGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXJ5</accession>
    <name>E3QXJ5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">GIY-YIG catalytic domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_10727</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="8">Forms a heterodimer with SLX4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the SLX1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="GG697396">
        <property type="protein sequence ID" value="EFQ35583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099603.1">
        <property type="nucleotide sequence ID" value="XM_008101412.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXJ5"/>
    <dbReference type="STRING" id="645133.E3QXJ5"/>
    <dbReference type="GeneID" id="24416092"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10727"/>
    <dbReference type="eggNOG" id="KOG3005">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030739_1_1_1"/>
    <dbReference type="OrthoDB" id="24645at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033557">
        <property type="term" value="C:Slx1-Slx4 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008821">
        <property type="term" value="F:crossover junction DNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10455">
        <property type="entry name" value="GIY-YIG_SLX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="entry name" value="GIY-YIG endonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03100">
        <property type="entry name" value="Endonuc_su_Slx1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027520">
        <property type="entry name" value="Slx1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048749">
        <property type="entry name" value="SLX1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050381">
        <property type="entry name" value="SLX1_endonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20208">
        <property type="entry name" value="STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20208:SF10">
        <property type="entry name" value="STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21202">
        <property type="entry name" value="SLX1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 8" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2 8" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="10">
        <location>
            <begin position="10"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ35583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="306" mass="34040" checksum="080D4BBEF9D30E12" modified="2011-01-11" version="1">MPVQSKPIPALYTVYILRSTVRHASLYIGSTPNPPRRLKQHNGEARGGAARTSRLSLRPWEMVGLVSGFPGMVAALKFEWALTNPHLSLHIPSASRITVSAGVKRNGHPRRPRASLSSILSNLQLLLSVPSFRRWPLTLHFFAKDVHKAWLLSSVNTAEPLRNTLDVVTDFGPDPAASSDDAKWGIHALPLDYTPIKEYIEKGQSITTFEREGHCVVCAEALPHRQGLLAVCPNEGCEGVGHLSCWSRHILRNEGEQQAVVPIQGRCPQCGGHVRWVDMMKELTLRERGAKEIDTLLKKKKRRTKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXY7</accession>
    <name>E3QXY7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10879</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697399">
        <property type="protein sequence ID" value="EFQ35724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099744.1">
        <property type="nucleotide sequence ID" value="XM_008101553.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXY7"/>
    <dbReference type="GeneID" id="24416244"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10879"/>
    <dbReference type="HOGENOM" id="CLU_2170879_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="110" mass="11811" checksum="4D1D34F98D2F9772" modified="2011-01-11" version="1">MTDKRPTSDPARPSFLMGARVGHQRQTRLVTRDIGVNLSVLVGAPAGQVTDNETTAPNTLAHIGARFPRPCANAAKHKGLASRDKGKRGTSQKPWTGERKMIRAELVDGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QY82</accession>
    <name>E3QY82_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">alpha-1,3-glucan synthase</fullName>
            <ecNumber evidence="2">2.4.1.183</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_10929</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>[(1-&gt;3)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose = [(1-&gt;3)-alpha-D-glucosyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19749"/>
            <dbReference type="Rhea" id="RHEA-COMP:11150"/>
            <dbReference type="Rhea" id="RHEA-COMP:11151"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28100"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.4.1.183"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase group 1 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.183" evidence="2"/>
    <dbReference type="EMBL" id="GG697401">
        <property type="protein sequence ID" value="EFQ35820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099840.1">
        <property type="nucleotide sequence ID" value="XM_008101649.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QY82"/>
    <dbReference type="GeneID" id="24416294"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10929"/>
    <dbReference type="eggNOG" id="ENOG502QQX3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000488_0_0_1"/>
    <dbReference type="OrthoDB" id="512920at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047657">
        <property type="term" value="F:alpha-1,3-glucan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070600">
        <property type="term" value="P:fungal-type cell wall (1-&gt;3)-alpha-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11323">
        <property type="entry name" value="AmyAc_AGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03791">
        <property type="entry name" value="GT5_Glycogen_synthase_DULL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000058">
        <property type="entry name" value="Alpha-1,3-glucan synthase Ags1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000073">
        <property type="entry name" value="Alpha-1,3-glucan synthase Ags2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000052">
        <property type="entry name" value="Alpha-1,3-glucan synthase Ags2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058659">
        <property type="entry name" value="Mok11-13/Ags1-like_CBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058656">
        <property type="entry name" value="Mok11-13/Ags1-like_GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058657">
        <property type="entry name" value="Mok11-13/Ags1-like_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058658">
        <property type="entry name" value="Mok11-13/Ags1-like_Ig_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058655">
        <property type="entry name" value="Mok11-14/Ags1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058654">
        <property type="entry name" value="Mok11-14/Ags1-like_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013534">
        <property type="entry name" value="Starch_synth_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47182:SF2">
        <property type="entry name" value="CELL WALL ALPHA-1,3-GLUCAN SYNTHASE AGS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47182">
        <property type="entry name" value="CELL WALL ALPHA-1,3-GLUCAN SYNTHASE AGS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26127">
        <property type="entry name" value="12TM_Mok13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26122">
        <property type="entry name" value="CBM_Mok13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26108">
        <property type="entry name" value="GH_Mok13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08323">
        <property type="entry name" value="Glyco_transf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26114">
        <property type="entry name" value="Ig_2_Mok13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26111">
        <property type="entry name" value="Ig_Mok13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003181067" description="alpha-1,3-glucan synthase" evidence="9">
        <location>
            <begin position="23"/>
            <end position="2351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1066"/>
            <end position="1092"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1927"/>
            <end position="1949"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1961"/>
            <end position="1978"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1985"/>
            <end position="2008"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2020"/>
            <end position="2040"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2052"/>
            <end position="2072"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2092"/>
            <end position="2117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2138"/>
            <end position="2155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2175"/>
            <end position="2196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2203"/>
            <end position="2220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2277"/>
            <end position="2295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2323"/>
            <end position="2343"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="10">
        <location>
            <begin position="68"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1661"/>
            <end position="1727"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1852"/>
            <end position="1895"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1709"/>
            <end position="1718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1859"/>
            <end position="1869"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ35820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="2351" mass="262017" checksum="D0B8CDD956736672" modified="2011-01-11" version="1">MSNSVLAWAITLLTASSTVVSGLKYTASEAEYNLNQNRLATNPHEYSGKRENHTFAKSPENWRFPYYTLFIDRFVNGDPENDNANGTLFEQDPLSNQLRHGGDVAGLVDTLDYIQGMGVKAIYIAGSPFINQPWGADSYSPLDLTLLDRHYGNITAWQEAIDEIHKRDMYVVMDQTMATMGDLIGFQGYLNSSTPFRTDEHKVQWKSSRRYLDFDIGNDYNETCQYPAFWFEDGNLVAKDVTSQLKGCYNSDFDQYGDIEAFGVFPDWQRQLAKFASVQDRLREWVPSVRQRLELYSCMTIQTLDVDGFRIDKAVQVTVDAQAEWSTAMRQCAKDLGKDNFMIVGEITSGNTLGSIYLGRGRTPGMASSLQLAQAVSLDATSGSASGSFIREPGKSALDAGAFHYSVYRFMTRFLGLSGNLEAGYDLPTDWVQTWNQMILTNDFYNANTGKFDPRHLYGVTNQDVFRWPAIELGTERMLLAYFITTLLLPGSPLVYYGEEQNFYVLDNTAENYVFGRQAFSPSPAWKIHGCYAGDNSVYVGWPVAKGRTGCTDPSVAYDHRDPSASIRNWMKRLFAFRDEYPVLEGGWLLQQLSNKTHGIQYVGSSVPTETGIWSVARGYLSNQNETGDPVWLVYHNSPNETTYEFDCSNEADAFLSPFDENSKVRNLFDTGGAGAITLESSTKDNGFNGNGKKAGCISSITMTPFEFRAYVPDTKWMDIAPSITGFEPGHDAPIDSTNANGQIPIALKFSTEMDCDAVTKAVSARVTVDANTENALTFDTPVCGSMNPIEKDSYIGAIASVWKWSANLQNVPDGIVKITANNITAPGGTTTKAVDHFLIRFGKPFNPVVFPATANYSRSLMQESGGVYYINHAAPGATKFRYSTNWGSSWSNWQPYTGARQRMIPQSWDGTDLQKWKGEHLMVQYYSKPLGSSSFVQHSDSSDIPYSRQWPHIFLHGPFNKWGYDAGLPNLMNQVDNNLWELHFMYEWPAQIQLNIWGINPDNQPDASFIYGDPNGDGVLDRLPPSSLSDNVVNLTSPPPMPALSYKLVLNDANWNYVAVPQGNMWIQIIFFFLLGLMPIVLAGLAGWIYMKGFYQVKINKSGFSKKGWLPLKLGNESNINFGEKGKSLEMSQIPQSPLSPAPAAAAGGAARRKVLIATMEYNIDDWKISIKIGGLGVMAKLMSQALSHVDLIWVVPCVGDVDYPLENEAEPMFVEVMGESFEVKVYYHQSKNITYVILDAPIFRQQTKADPYIARMDDLESAILYCAWNSCIAESIRRFNVDIYHINDYHGAAAPLYLLPQTIPVCLSLHNAEFQGMWPMRTEEEQKEVYSVFNLPPKVVKDYVQYGSAFNLLHAAASYLRIHQRGFGAVGVSKKYGDRSLARYPIFWSLKNIGQLPNPDPSDTGEWNPDEDISNAQDEIKIDETFEANRATLRRQAQEWAGLEVNPNADLFVFVGRWSLQKGVDLIADLFPSILEKYPSVQLIAVGPVIDLYGKFAALKLNKLMEKYPGRVFSKPEFTQLPPYIFSGAEFALIPSRDEPFGLVAVEFGRKGALGVGARVGGLGQMPGFWYTVESMSPTHLLQQFKQAIASALSCKPRKRALMRAWSAKQRFPVAQWIRQLDTLYNESIKIHNKEAAKQKKAGGVRNLTDSSLRSSVAVSEYGSELTPTGSRAPSPLPPPSRIASPAGRINSPDLGTPNMPWSTIPSSRRGSFSSSINGRDSMLAPRESMFATGRESMVSVDSFAMRAQHDSPQTPGFDGLGLPQPSFYKQQRNSSQLSLPDVVGDRHDLKLQNVDQNFTDKNGEFYAEFEQMLNSLTAKNSGTDLCIENFLKKSEKKWFARYRDAKLGRRDHSRSRSPAPSRPGSSKGLGATFDGDRGRSRTPSGLTAGSHYDDSPVDDEFLLGDNYNAPTGLKKILSIRIGDWPVYAFFLSFMQVISINSYQIVLLTGETNQTPSKLYIVAATYLVTSILWWVLLRLTKSVYALSLPWVFFGMAFFLLGVSPYLEPWQSRAAMQDAATALYSAGASAGALSFALNFGDEGGAPTKQWITRALSVAGVAQVYSLMLWYWGSLTHTPETSPMSFFDGTTIPKALVICVPIAIMLWAIGAILFLGLPDYYRQAPDNIPGFYISLVRRKLVPVFFIMIIIQNYWLSAPYGRNWQFLFASQFIPGWGVVLLALGFFVVLWSIILYVFSFFSESHTWLLPIFAIGLCAPRWAQMLWGTSSMGMYLPWAGGPVGSAILSRCLWLWLGLLDNIQGVGLGMMLLATLTRQHVLAVLIGAQVVGSAFTMLARATSPNALSPNTTFPDFSQGLMPGISSWWFWICLGFQLVIPVLFFKFFRKEQVSKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYD2</accession>
    <name>E3QYD2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11061</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697402">
        <property type="protein sequence ID" value="EFQ35870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099890.1">
        <property type="nucleotide sequence ID" value="XM_008101699.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYD2"/>
    <dbReference type="GeneID" id="24416426"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11061"/>
    <dbReference type="eggNOG" id="ENOG502RJZ9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_590525_0_0_1"/>
    <dbReference type="OrthoDB" id="4776990at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="7"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="463" mass="52172" checksum="F0C55F4BEF6D5B99" modified="2011-01-11" version="1">MPSSLLLSLPDEVLLQIVSHLTPPLDGLDIPFQAYTDPDGVVVTNRVALYRLAFVCRRLSDLAIPHLYQTVYLWGQTRLQSLLQTLLERPELGDNMRVLSYVSCLGTDHYPTDVLCPYKRTEWRRLVDASSRFPDRIKNFVREANTELEFAQIVFALVLYSSPNLSTLHMRMPFAAGEYQKLKDIITPDIETAEGCPRVLSSLTRVMLEPMPDFPGASFWPRRELPCLLRLPKLRSVELGSAVFRPAVLDPGDGWGDDGSWKNVEEIRLVRSSMWGQGWHAICALCPNLKLLEMGPSGVAEQPADGEHNLNTALSLVADTLETFSFEGILAGNFSQHVGGDGTLTCLPKMKALRNVKLDIGILYGNPEGVQSIDLRDRLPPSVEILDLAELWHDVEVDQLSTKERCMYEKGLQDALHKLVFDSREALPHLKEITFRPNPFYDPLPIPDTLKYYPSKVAFKLVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYI3</accession>
    <name>E3QYI3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">alpha-L-fucosidase</fullName>
            <ecNumber evidence="3">3.2.1.51</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_11029</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 29 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.51" evidence="3"/>
    <dbReference type="EMBL" id="GG697403">
        <property type="protein sequence ID" value="EFQ35921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099941.1">
        <property type="nucleotide sequence ID" value="XM_008101750.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYI3"/>
    <dbReference type="STRING" id="645133.E3QYI3"/>
    <dbReference type="GeneID" id="24416394"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11029"/>
    <dbReference type="eggNOG" id="KOG3340">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002934_4_2_1"/>
    <dbReference type="OrthoDB" id="6039950at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004560">
        <property type="term" value="F:alpha-L-fucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006004">
        <property type="term" value="P:fucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016139">
        <property type="term" value="P:glycoside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016286">
        <property type="entry name" value="FUC_metazoa-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000933">
        <property type="entry name" value="Glyco_hydro_29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057739">
        <property type="entry name" value="Glyco_hydro_29_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10030">
        <property type="entry name" value="ALPHA-L-FUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10030:SF37">
        <property type="entry name" value="ALPHA-L-FUCOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01120">
        <property type="entry name" value="Alpha_L_fucos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00741">
        <property type="entry name" value="GLHYDRLASE29"/>
    </dbReference>
    <dbReference type="SMART" id="SM00812">
        <property type="entry name" value="Alpha_L_fucos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Glycoside hydrolase family 29 N-terminal" evidence="7">
        <location>
            <begin position="294"/>
            <end position="657"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ35921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="764" mass="84830" checksum="8143A978535DE54A" modified="2011-01-11" version="1">MQQISVPLDLIPLFNNKGFGTRPGEASFDALNQSFPEPTVGPEFVSPDTGIHYSFPGYTGPAEPDNLICNGQKVTVPPATYFSASFLVAGDVEGSTVSGNVSFVYSDNTTSEFELRTLNWFSFLTINRGEIIFPSRYTANGSDFNSSHIFERTTALPPGKKLSSIILPVKNNATEGRLHVFAVSLWQQSPDVGVQSVRPTQKWMGNDTQIVEVTINNAGSSCVSGNGLNLTIHGDGFHTVSPGHLKRLCPGDQKIVAVGVNGASDGFVSVSVEISSEDTKRTTSVDNVEIGLAEWTADSDSLSKHESPEWFDDAKYGVFIHWGPYAVTGWGNSTPYESYSEWFWWYSTHHPEGDRSNFYGYRLDTYGPDWAYDDTFPEFNASKFDAKEWVDLFADAGAKYFVITTKHHDGFALFDAGKTSNRSAIHYGPKRDLLKELFDAAETYQPSLKRGTYFSLPEWFNPDFGPYGFVQFPTPSAVSWPGTLAPNPYTGEPEPYTGHVPVNDFIVDLMVPQMETLAYDYGTDIMWCDCGAANGTAGFAAEWWNKARAEGRQVAINSRCGIPEAADFDTPEYQTFASAQSRKWESNRGMDPYSYGYNRATKPEEYMNATTIVYSLVDMVSKNGNFLLDIGPRADGTIVEAEMKNLREAGKWIKSHEEAIFNTTYWFVQSEIIGGPDVRFTQTDDAFYTVFLEKPLSIDGWVTIQAPIPILRGDSVSLLGVNGGEELEWDLDNSGSECELKIKVDEALIEEDEFGWVFKVLYKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYL3</accession>
    <name>E3QYL3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Major facilitator superfamily transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11095</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697405">
        <property type="protein sequence ID" value="EFQ35951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099971.1">
        <property type="nucleotide sequence ID" value="XM_008101780.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYL3"/>
    <dbReference type="GeneID" id="24416460"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11095"/>
    <dbReference type="eggNOG" id="ENOG502QWBF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2468941_0_0_1"/>
    <dbReference type="OrthoDB" id="194139at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="88" mass="9370" checksum="BB1740D1AD61E275" modified="2011-01-11" version="1">MVGTLFTTLSMMDTMGSLLAGPLVAKTFSWSMRLDGIWKGMPDVISFVMCGLASLALSRAGSGSLPSKHVDDDEESRSLLAREQSSAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYN2</accession>
    <name>E3QYN2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Histone-lysine N-methyltransferase SET9</fullName>
            <ecNumber evidence="12">2.1.1.372</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Histone-lysine N-methyltransferase set9</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">SET domain protein 9</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">GLRG_11114</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Histone methyltransferase that trimethylates 'Lys-20' of histone H4 to form H4K20me3.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-lysyl(20)-[histone H4] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(20)-[histone H4] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:64456"/>
            <dbReference type="Rhea" id="RHEA-COMP:15554"/>
            <dbReference type="Rhea" id="RHEA-COMP:15998"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="EC" id="2.1.1.372"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.1.1.372" evidence="12"/>
    <dbReference type="EMBL" id="GG697405">
        <property type="protein sequence ID" value="EFQ35970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099990.1">
        <property type="nucleotide sequence ID" value="XM_008101799.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYN2"/>
    <dbReference type="SMR" id="E3QYN2"/>
    <dbReference type="STRING" id="645133.E3QYN2"/>
    <dbReference type="GeneID" id="24416479"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11114"/>
    <dbReference type="eggNOG" id="KOG2589">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013724_0_0_1"/>
    <dbReference type="OrthoDB" id="6627536at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140943">
        <property type="term" value="F:histone H4K20 trimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10524">
        <property type="entry name" value="SET_Suv4-20-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1700">
        <property type="entry name" value="Histone-lysine N-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041938">
        <property type="entry name" value="Hist-Lys_N-MTase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025783">
        <property type="entry name" value="Set9_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039977">
        <property type="entry name" value="Suv4-20/Set9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12977:SF4">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE KMT5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12977">
        <property type="entry name" value="SUPPRESSOR OF VARIEGATION 4-20-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51567">
        <property type="entry name" value="SAM_MT43_SUVAR420_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 17" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="8 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SET" evidence="16">
        <location>
            <begin position="119"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="276"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="346"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="744"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="305"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="373"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="439"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="764"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="778"/>
            <end position="788"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EFQ35970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="794" mass="87304" checksum="B25FD3D9A7E3778A" modified="2011-01-11" version="1">MPPSCAAAKKQKQKKTLTLAQLASYDDFLTDALVDHVFYWTTIPKNRNSYHPSRGVREEDITRIIQEEIVVKKDLEAAESKLLVTDGFRKFFAALKTDKVKDDFKRHMRRYTQVYLPDCPFEVNSTNRYTIVSHEAAITARRFIRRNETIKYLAGTQVNISPEEEREMTARKKDFSIIISARSKCASLFMGPARFANHDCGANAKLMTTSSATIEIIATRNIDVGEEITVTYAENYFGEDNCECLCKTCEDRCTNGWAPAEGGVVVKRSIEESAMDGYSLRRRRRDDSSGPSSRTPSVTPNIRPRVSKSRLRSGKPNRDSLAVGSPMSDVLSPDKELSFDLLVTPPITPSKRRKLSATQAVTAPTEEAHVSSRDSSSSGSVRSMSLTSGGNEDGSVTDITEPEKDTPEPSQSQKRSDLVKEEECEESTGQVLAHAAPFSPQQQGQRGTMATMPVKNSASIQTTSVMASRSIPISSLCNPPSPPSKPKGRGPSGWTATAYSMSITNVTARQDDRMSIAAAVCDSVDIKPAMMPNAGTTTGSGRSGSKSMQVDRVPLTNEAPESSHQDHVVQAPKVVAVGSIEQDVPSNRNSDIVKALRVEARVPTENPALVTDDTQVCAKVDETTVEAGAAGKPSAAGLKKRKYQRRTFIKETTPPAKTRTPGDYTLTPLLLSEPQTAWVRCMNCETAFVQQNAYYTKSSCPRCERHSKLYGYIWPKTEKAGPRDKEERILDHRTIHRFLGRDDEARIRGRKRPTGGLSETLEGDTGKDSGEGEDKAGLRRSGRMRKASIKVACP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZ47</accession>
    <name>E3QZ47_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11279</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697410">
        <property type="protein sequence ID" value="EFQ36135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100155.1">
        <property type="nucleotide sequence ID" value="XM_008101964.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZ47"/>
    <dbReference type="GeneID" id="24416644"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11279"/>
    <dbReference type="eggNOG" id="ENOG502T4VJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_574919_0_0_1"/>
    <dbReference type="OrthoDB" id="10504134at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="475" mass="51880" checksum="5787B8EDD9B88C6F" modified="2011-01-11" version="1">MLGLQAVSWAVAVCARKMAGLLWLVISSRLFLALTAVTLTLSLAFLLFQSWVAWFTELPVISSVLFCARSIAVFLASWRPAQVARLPDNLLGNNANSVTMAFNTSDVTALRIFPHGSDMDKGVRQLSAIPVGAAKAHRGGARPSFHVAVVTLEEVLADATRGSRGSPWLSMSSSLPSAWDESWSRIRSVVAKMCAEEARFAEKAVANGLLVFQHAHALQRELAETPVSHSIALRQKRLQSRWKVALWLEQLWQGLRHWAESCMGRWLMVGGASACQNHLHDPAGQQVDLRLATFGSLVDSALKTLPDLTVSLELGPALEEDVCMMGAMLGNAVEICEGRVARTLEAGRGQKPLLLPGETREAAVLTPDIDTIGAAAYELRYFDVVGRTVCAEAKQAVGTFTATKHSVVWLAKELQAIKAAAVRLRSYLRQEVSGALGGDDDDKNQRASWAENELRVLLVPKLIYGLEQTYFRQED</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZ89</accession>
    <name>E3QZ89_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoribulokinase/uridine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11318</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697413">
        <property type="protein sequence ID" value="EFQ36177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100197.1">
        <property type="nucleotide sequence ID" value="XM_008102006.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZ89"/>
    <dbReference type="STRING" id="645133.E3QZ89"/>
    <dbReference type="GeneID" id="24416682"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11318"/>
    <dbReference type="eggNOG" id="KOG2702">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067202_1_1_1"/>
    <dbReference type="OrthoDB" id="6362633at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10285">
        <property type="entry name" value="URIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribulokinase/uridine kinase" evidence="1">
        <location>
            <begin position="34"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="236" mass="26177" checksum="CEAEE84B40A6F279" modified="2011-01-11" version="1">MESTYKALVQHTLLEWNEKRRSASDTAVVHPRLIIAIAGPPGSGKTTIARRVVSDLNSSPEPRPKSVVVSADGFHLPLEVLRALPDATEAIARRGAPWTFNGPGLVRLVRQLRASAGLRPVQAPTFDHRLKDPVPRGLTIEADVDVCLVEGNYLLVDEEPWSQVVQLVDDRWLVRVEPTLARNRVAARHVAAGVEDTMEKALFRAESNDMVNGEYIVRRSEGRYDLLIDSVEELPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZF2</accession>
    <name>E3QZF2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">XFP domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_11385</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the XFP family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697415">
        <property type="protein sequence ID" value="EFQ36240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100260.1">
        <property type="nucleotide sequence ID" value="XM_008102069.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZF2"/>
    <dbReference type="STRING" id="645133.E3QZF2"/>
    <dbReference type="GeneID" id="24416749"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11385"/>
    <dbReference type="eggNOG" id="ENOG502QUUF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013954_2_0_1"/>
    <dbReference type="OrthoDB" id="2532903at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016832">
        <property type="term" value="F:aldehyde-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02011">
        <property type="entry name" value="TPP_PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005593">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018969">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019790">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018970">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019789">
        <property type="entry name" value="Xul5P/Fru6P_PKetolase_ThDP_BS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003617">
        <property type="entry name" value="PRK05261.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003619">
        <property type="entry name" value="PRK05261.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31273">
        <property type="entry name" value="PHOSPHOKETOLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31273:SF0">
        <property type="entry name" value="PHOSPHOKETOLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03894">
        <property type="entry name" value="XFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09363">
        <property type="entry name" value="XFP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09364">
        <property type="entry name" value="XFP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017245">
        <property type="entry name" value="Phosphoketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS60002">
        <property type="entry name" value="PHOSPHOKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS60003">
        <property type="entry name" value="PHOSPHOKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal" evidence="7">
        <location>
            <begin position="24"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal" evidence="6">
        <location>
            <begin position="602"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF09363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ36240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="818" mass="92300" checksum="F9B03BC311843DCF" modified="2011-01-11" version="1">MTDKEAESISPYGPARSTVKGEPLSKEDIEKYNDFFKASLYLCLGMIFLKENPLLREPLKKEHMKLRLLGHFGSAPGQVFTWMHFNRLIKKYDIDSIFISGPGHGAPAVLSQSYLEGVYSEVYPDKSEDIEGMQKFFKSFSFPGGIGSHATPETPGSIHEGGELGYSVSHAFGAVYDHPNLIALTMVGDGEAETGPLATAWHSTKFLNPIVDGAVLPVLHLNGYKINNPTILARISHKELENLFLGYGWQPYFVEGDDVDTMHQAMAATMEHCVLEIRKFQKQARDSGKAFRPIWPLIVLRSPKGWTGPRKIDENYMEGYWRAHQVPVPSAATNPEHLKVLEKWMRSYEPERLFKDGRISDELKALCPTGNRRMSANPVANGGLLRKHLKLPDFRNYAIKVDKAGGTTAASMNNMATYLRDVIALNQTSFRLFGPDETESNKLGAVYEAGKKVWMGEYFEEDANGGNLAPEGRVMEMLSEHTCEGWLEGYILTGRHGLLNSYEPFIHVIDSMVNQHCKWIEKALEVEWRNKIASLNILLTAVVWRQDHNGFTHQDPGFLDVVANKSPEVVRIYLPPDGNCLLSTMEHCLASSNYVNVIVADKQDHLQYLTMDKAIEHCTKGIGIWPQFSTDQGEDPDLVMASCGDISTHESLAAIDLLLQHFPDLKIRCVNCVDLFKLISHEDHPHGLTDAEWVALFTDDRPIIFNFHSYPWLVHRLAYKRPGNMNLHVRGYKEKGNIDTPLELAIRNQTDRFSLAMDAIDRMPQLHNRGAAARETLRNQQIAARIEAFETGMDPPFLKNWSWSHNGLWKQTVSRITS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZW3</accession>
    <name>E3QZW3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_11569</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697422">
        <property type="protein sequence ID" value="EFQ36401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100421.1">
        <property type="nucleotide sequence ID" value="XM_008102230.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZW3"/>
    <dbReference type="STRING" id="645133.E3QZW3"/>
    <dbReference type="GeneID" id="24416933"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11569"/>
    <dbReference type="eggNOG" id="ENOG502RQ2B">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066042_6_2_1"/>
    <dbReference type="OrthoDB" id="3501153at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053008">
        <property type="entry name" value="Phomopsin_biosynth_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35896">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35896:SF3">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ36401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="147" mass="17083" checksum="724AA8DF98EAE390" modified="2011-01-11" version="1">MAIPYRSGSSLQRTVNVTECGHTPDEAIARGCRFESHNFACTPPDCYDRELDELWNEKDWGYSRNAEGTDLLSKEEAPEGKLSWAYVTLNQHMSHCVLIWQKYQRAAMQDLPTDNWTSSFPHTYHCGHMMVQWGINRSEYNSILYTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3R034</accession>
    <name>E3R034_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11617</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697426">
        <property type="protein sequence ID" value="EFQ36472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100492.1">
        <property type="nucleotide sequence ID" value="XM_008102301.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R034"/>
    <dbReference type="GeneID" id="24416981"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11617"/>
    <dbReference type="eggNOG" id="ENOG502T5VZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2687690_0_0_1"/>
    <dbReference type="OrthoDB" id="4849054at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="74" mass="8224" checksum="0B46EE5668E5AB0A" modified="2011-01-11" version="1">MADKERVRTAFCSFLVSSEATACAEVERRLALFAMHQHDIEDVESETEVGRQSQPLSSRQGHQEDTSQGQAQDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0I7</accession>
    <name>E3R0I7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Beta-ketoacyl synthase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_11770</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697447">
        <property type="protein sequence ID" value="EFQ36625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100645.1">
        <property type="nucleotide sequence ID" value="XM_008102454.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3R0I7"/>
    <dbReference type="GeneID" id="24417134"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11770"/>
    <dbReference type="eggNOG" id="KOG1202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_31_0_1"/>
    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901336">
        <property type="term" value="P:lactone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05195">
        <property type="entry name" value="enoyl_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000209">
        <property type="entry name" value="Polyketide synthase Pks12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000019">
        <property type="entry name" value="Polyketide synthase type I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049552">
        <property type="entry name" value="PKS_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF29">
        <property type="entry name" value="ASPERFURANONE POLYKETIDE SYNTHASE AFOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23297">
        <property type="entry name" value="ACP_SdgA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21089">
        <property type="entry name" value="PKS_DH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="9">
        <location>
            <begin position="3"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="10">
        <location>
            <begin position="934"/>
            <end position="1255"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="8">
        <location>
            <begin position="2293"/>
            <end position="2370"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="7">
        <location>
            <begin position="934"/>
            <end position="1070"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="7">
        <location>
            <begin position="1098"/>
            <end position="1255"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="7">
        <location>
            <position position="966"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="7">
        <location>
            <position position="1165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ36625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="2378" mass="254438" checksum="A0DEC8335C68412F" modified="2011-01-11" version="1">MPKSPIAVVGLACRLPDEASSPEEFWKLLLEQRDTLSVPHNRWNTDAFHHPGRNKPQTIAARSAHFLKRDVMAFDAAFFNINASEAVALDPQQRFVLEVTYEALESAGLTMAGVSGSRTGCYVGFSSCDYRDSILRDTETSPRYTDLGTHAEMLSNRTSWFYNLKGPSMTVSTACSSSLVAVHMACQSLLAGETDLAVAGGVNLMLNPECGIYLSSLTMISPEGHCKSFDASGDGYGRGEGCGMVVLKRLDDALRDGDPIRAVIPGTGVNSDGFTQGFTMPSSESQAALIRDVYEGAELDMSDTQFVECHGTGTKAGDPIETRAIYETLGKKASSSQPLIIGSVKPSIGHLEGASGVAALIKSILALEKGYIPPQMFFSTPNPKIPLREWNLSVPTALMPWPKTNGPRRASINNFGVGGTNCHVIIEEGIPPRGRQHQPALDSSAAAAHDRKKRLFVISSQDQKGLVRVAQSIADYLGNKSTHANATTRAADLAYTLGNKRSRFSWKKSCIATDLEDLRSRLLAMTSDGAVRSHAAPRIGFVFTGQGAQWPLMGLELMKFDVYKASFEKCQGYLAELGCSWDAAEELRRPAETTRIKSPELSQPLCTILQIGLADLLMSWGVRPARVVGHSSGEIAAAYCAGHLTARDAVEVAYLRGKFSAGLSSMAPGRKGGMLAVGCSQDEAEKLISNVTSGRLAVACVNSPFNVTISGDAAAIEELHEKLRATSMFAARLKVEVAYHSEHMETIYPGYVQSLRHIRPSAGGLPPDVPKDVITMVSSVEAAEVDPEALGAFYWGRNLVSPVLFSDALRQLVCPAAEGSVDADGSASVIDLLIEIGPHPALKQSVKEILATSGVKGIGYLPSLSRGMNDEDMALSLAGNLFAAGAAVDVSKVNGDSGAAMLTDLPPYPWQHSRKFDATPRIGREHNMRPHPQYGLLGAPMPSVNPDEHVWRGYVRLDQESWVRDHKITGVIVYPGAGLVAMALEGARQLAEAGRAVRVYKLRDVSIGSAAIMNEDRPTEFVLHVRPHLLGTAGSAPSAWLEFTISSSGGPDMPLRQNCRGLLRIEYEADDGSAASREEEAAAAACLAEYEAAAAACVEELPMSDFYPDLAKVGLGFGTTFQNMKKLHYRPGESVYDLAIGDPGESFDTGRTGRRTHLIHPTTLDSTASASFAACYRGPGEPPERPYIPVFISEFEISADIPFEAGTPVKGFARAKRRGINEMESEVYMFDKALSKCYLSIRGYRATSDIASDASSAGEDRSEASPGLCYSTRWETAFGLLTNEELRVVAASAGLTPDDKLEKIAQMILHEHPDTTILEVLAKQHESSAKDNTVLGRLSLSRPDQARHAVIGDTAAASGDSSREVLRLKPGQPADTTFDLILAGQACRDLMCGDADLGLLLEHVKPGGRLICGFDCEGLDKSKLPEGCRVDDLSLDAAAEAGMTLITAPPVVADPDPGAFPVKGNRVTIVEPPMPSGAVQRFSTALAELLQKTKGLETRTVPWTPELATAVLSERVVCLLELEKASMDNLSEPDFGLVKDMIVKAASLLWVTALKNDPAASVIEGALRVARRELGNPELKTLHLSGLDRGPELATRVLGSSTKDTEFIEDGNGMLKVSRVLEDNGLSAEVASYAGTETQMASIKTCGFPLRLGISRPGLLDTLRFGPQEDVGQLKEDEVEIHIKASGMNFRDVMISMGLIADPRLGYEGAGVVLRTGSKVTSVKPGDRVSAHILGSHATRARTLDIMCARMADEMSFAEGASFPCVFTTAYHALVNLARLRAGQSVLIHAAAGGVGQAAVQLACDMGLTIYATVGSAAKKALLMEQYGIQEAHIFSSRDSSFVKGVKRVTGGRGVDCVLNSLAGELLRQSMYCLAPLGTFVEIGSRDISENTRLDMAPFAAGITFTSFTLLQVLQHDPGLMAETWRKTFDLVRRKVLRPPSPLTIMPVQSVKEAFRLMQGGKHSGKIVLSLEHDGDVPIVRDPKTALQLDPASTYLLVGGLGGLGLSLAQMLVDSGARNVAFISRSGDTQPSAKAAMAAISACAPGIQARAYAADVSDKVSLADALARCGAELPPVRGVVQMAMVLRDGVFEQMSHDGWTAAIRPKVDGTRNLHEHFGPAYPLDFFIMCSSISGVIGNRGQANYAAANAFQDALAYHRRSLGLRGCAVDLGIMRDVGVLAEKGAAGDLVKWEELLGIREATFHTLMKTIINGEMRRPPAAEFPAQISVGLATAGAFEAAGLTLPDWLTADARFGHLAAVRSGVSPKDGSGGDAAQTAVASLPRRLAGSRTRDEAVAAVIDGLVDKVSNILLTPASEVDPGRPLYMYGVDSLVAMEIRNWIHRDVKSDIALFDVLEAVPITSFADKVVKRSKLCVFKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q273</accession>
    <name>E3Q273_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_00318</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089194.1">
        <property type="nucleotide sequence ID" value="XM_008091003.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q273"/>
    <dbReference type="STRING" id="645133.E3Q273"/>
    <dbReference type="GeneID" id="24405683"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00318"/>
    <dbReference type="eggNOG" id="KOG0504">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1229836_0_0_1"/>
    <dbReference type="OrthoDB" id="20872at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0085020">
        <property type="term" value="P:protein K6-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF8">
        <property type="entry name" value="BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="15"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="85"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="123"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ25174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="225" mass="24777" checksum="8A9704112E4FCAE1" modified="2011-01-11" version="1">MLFKHGAILNCKDNIGETPLFSAVRRSAGPILDRLLELGADVSATDTEGRTALWALPIKSYSVYLVDKGSRLLQKGLDPMHRDNLGQTFLHVACHSAVVDRLYLDVVREAVKFGLDVDALDDSGRTPLMNAARSGNQDFILFLFTLGVDANRVDHDGRTLLTEAVRSCDRRLGSYDSMVHRFLEYGVKPHASAEAEHNPLFLAVGNASEEVVEQLLEHIDIGLHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2L9</accession>
    <name>E3Q2L9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00464</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089340.1">
        <property type="nucleotide sequence ID" value="XM_008091149.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2L9"/>
    <dbReference type="GeneID" id="24405829"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00464"/>
    <dbReference type="eggNOG" id="ENOG502TFE2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_552076_0_0_1"/>
    <dbReference type="OrthoDB" id="4844977at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="354"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="406"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="175"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="432"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="445"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ25320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="499" mass="53508" checksum="0E6DCEBBF7D1A6EE" modified="2011-01-11" version="1">MSSNGFSSYTVPYSGVVGTANFVPGAATHPPAPQDKRTQGIFRLPVVAGEPATASTARSKGESKAMGAAAGDPFQDAIPARFASAGVSAASGGIAIVTGGLGAGGFPSPSEICAASGLGQVSGQKKEHPKGVGLNNKDQFRFGTDGQYDDEGMPPSPTLMTMSAQRHSDRALPVIARELKAVKEENQRLRDANLRLQSRVISNDISGHLVASLQSTNKQLETQTESLYKQMADIQQQAQRFLRHRNRLRSRLINTEDSLMELVDLIVRLENIISRIDPDIFVTFPYEVQRLLTSIHEEWKYQEYCKCFKPEELEDDASSVSTIIEPQNAVLDDSLSLIIGSSYETAILSSATSGDASYNRVKNGPSKPDDVAANTSKDDSVNPPGGIDDDISNAELLRQLFQDHTIGGLGTKGSGQQTPRRVRPSENLLDFSSPGTPSSIGTPRTVYSSSPENGQGTHVTYGLQTSQSAHNAQNEQGAESAEVADSFDSLGIHNNIHKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2M7</accession>
    <name>E3Q2M7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fungal specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_00472</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089348.1">
        <property type="nucleotide sequence ID" value="XM_008091157.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2M7"/>
    <dbReference type="STRING" id="645133.E3Q2M7"/>
    <dbReference type="GeneID" id="24405837"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00472"/>
    <dbReference type="eggNOG" id="ENOG502QYWX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004083_5_2_1"/>
    <dbReference type="OrthoDB" id="424974at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF85">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="30"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ25328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="661" mass="74645" checksum="A75242F4B6B11637" modified="2011-01-11" version="1">MGTLQARDQPSAVAHVIAEPSEKRQGRRPACVECRRRKIKCDRQYPCVSCIALDHECRQPPPGPARRPRRRNHHELYDKIARVESLLAQCAIPLEHKESRSQLSDLPSYMLHSGEPDSFQQPAALAQPQRQQPKGTLVHVWNGGLEFRDSKAMAVVFDDLQTIRALIDVELEQEAWLPLVEAPGQRQQSCDTSIPFTDQLSACVPPAHAIDVLWRVFLDRVNPVTKVIHVPTFRMRVIEAINDFTSVPLATAALLFSVFLTASGSLSRQEHWDELGRSQADTIADFTLGLKLALTELNYLKNHNPEVLCSLALYSLFQQTRNGSSDPWILNGVVVNIAYRLGLHLDGSHANLSAFQCEMRRRLWWQIVILETRSGGAFGTGSHLLPSHRDTRIPLNVNDEDLSPTMPTEPCPHDGPTEMSFCIVTYELRKQALAQPRLWSIDDILWRQLPSPANPYSSPSAEMLGVMTALQWFSKDIDGVLHPLENNLCPDPASNPLHAMAQCNREALSRIIQLLVTPMEESPEWGTEVLGPDDNFFRISLAANEEALRARKAAGRRFAWYADIDFKMQGFYYLGAQLQSRPAGSMAHRVWSVMEDTYALHEELWELRDKENMTLCNLLLSAWDRRSVHLATSHEVLPEPPFLSRLREQVMVMKAEALGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2T6</accession>
    <name>E3Q2T6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cullin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_00059</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the cullin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ24915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008088935.1">
        <property type="nucleotide sequence ID" value="XM_008090744.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2T6"/>
    <dbReference type="STRING" id="645133.E3Q2T6"/>
    <dbReference type="GeneID" id="24405424"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00059"/>
    <dbReference type="eggNOG" id="KOG2167">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004747_7_0_1"/>
    <dbReference type="OrthoDB" id="27073at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000014">
        <property type="entry name" value="Cullin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1310.10:FF:000031">
        <property type="entry name" value="Ubiquitin ligase subunit CulD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1310.10">
        <property type="entry name" value="Cullin Repeats"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.130">
        <property type="entry name" value="Cullin, Chain C, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045093">
        <property type="entry name" value="Cullin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059120">
        <property type="entry name" value="Cullin-like_AB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016158">
        <property type="entry name" value="Cullin_homology"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036317">
        <property type="entry name" value="Cullin_homology_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001373">
        <property type="entry name" value="Cullin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019559">
        <property type="entry name" value="Cullin_neddylation_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016159">
        <property type="entry name" value="Cullin_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11932">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00888">
        <property type="entry name" value="Cullin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26557">
        <property type="entry name" value="Cullin_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10557">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00182">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00884">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75632">
        <property type="entry name" value="Cullin homology domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74788">
        <property type="entry name" value="Cullin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50069">
        <property type="entry name" value="CULLIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Cullin family profile" evidence="7">
        <location>
            <begin position="496"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="11"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="55"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ24915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="878" mass="100237" checksum="D230930140FC9344" modified="2011-01-11" version="1">MPSNSPPVVEGALPTRATGRTGGTAALINDTDSPPRRRPRVDSDVSRSSTLAPHQQQSTQQSTKPSPKRFKFGADDSSPSHSAMSTKMKGKLPEVIDLTQSNSYRPYTGAKKLVIKNLRPAARNEQLEQYYKRTNQELVDALQDIFNGGRPRVPLERLYRAVEDICRRGQDHELELYEILRRNCEEHLAHGVLRSIKFRGGNTDVDMLRSVLQHWRVWNSQIMTIRSTFSFLDRTFLLKEKGYPSINDMTISQFKRMAFPSRDDPNGQSPGGRALRGIYDLMYYDRLGDERFDAALLKDSIMMLHVFNIYTKYFEPRFIEISEHYFEEFAEERSASSLKEYILACESLLKREDYRCNEYNLDSTTKKQLLDAAHGILVKNYSDKLLNVESLSKLLSDYEVDSMKALYDLLRLSGIQKKLKEPWSAYIRKTGAIIVADKERGDEMVQRLLELKRSLGLIVRDAYGGDSDFVNDLRNAFGDFMNDRSIAATWTSGTSKVGEMIAKYVDMLLRGGIKALPKAMLSDNKDRAAAEQSGLASAGDEDAELDRQLDQALELFRFIQGKDAFEAFYKKDLARRLLMGRSASQDAERNMLRKLREECGMNFTHNLEQMFKDVEVAKEEMEAYKQWSEGTGVDRAPVDLSVMILSAAAWPTYPDVKVHLPDDVAKQIERFDQYYKNKHTGRLLNWKHALAHCTVKAKFPKGTKELLVSAYQAIVLVLFNEVGLEGFLTYEQISHSTNLQGGELVRTLQSLACGQFRVLTKHPKGKDVNPTDTFTINKTFVHPKIRLKINQIQLKETKEENKATHERIAQDRRFETQAAIVRIMKSRKEMSHGELVAEVINLTKNRGAVDAAQIKKEIENLIDKDYLEREGNTYTYLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q389</accession>
    <name>E3Q389_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Iron-sulfur cluster assembly accessory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00212</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HesB/IscA family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089088.1">
        <property type="nucleotide sequence ID" value="XM_008090897.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q389"/>
    <dbReference type="STRING" id="645133.E3Q389"/>
    <dbReference type="GeneID" id="24405577"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00212"/>
    <dbReference type="eggNOG" id="KOG1119">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069054_1_0_1"/>
    <dbReference type="OrthoDB" id="1938621at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.300.12">
        <property type="entry name" value="HesB-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000361">
        <property type="entry name" value="ATAP_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43011">
        <property type="entry name" value="IRON-SULFUR CLUSTER ASSEMBLY 2 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43011:SF1">
        <property type="entry name" value="IRON-SULFUR CLUSTER ASSEMBLY 2 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01521">
        <property type="entry name" value="Fe-S_biosyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="HesB-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core" evidence="2">
        <location>
            <begin position="108"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ25068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="243" mass="26824" checksum="01EB8C8A1E3274EA" modified="2011-01-11" version="1">MATTLRCAHAPSSANIFVLLARRTNPTSNHPAPILSVLVPRWRSMTTATRGFSTGRKCCSETFTRRSLPQKYHRRTLQHQTRAFTASAARGQTRCAWNPKKDEDGQEMKLEITDRAGKRLSEIMKKDKNPNLALRIQVESGGCHGFQYLMSLVTLPGGGEAGEEWSKVVGEDDTVFQYLPDNADASCISFEGPKVVIDEPSLELLKGSKVDFTMELIGSQFKITDNPYASSSCGCGTSFDIKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3M6</accession>
    <name>E3Q3M6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Folylpolyglutamate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_00772</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the folylpolyglutamate synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089648.1">
        <property type="nucleotide sequence ID" value="XM_008091457.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3M6"/>
    <dbReference type="STRING" id="645133.E3Q3M6"/>
    <dbReference type="GeneID" id="24406137"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00772"/>
    <dbReference type="eggNOG" id="KOG2525">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015869_3_2_1"/>
    <dbReference type="OrthoDB" id="5212574at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004326">
        <property type="term" value="F:tetrahydrofolylpolyglutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="entry name" value="Mur-like, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001645">
        <property type="entry name" value="Folylpolyglutamate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018109">
        <property type="entry name" value="Folylpolyglutamate_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01499">
        <property type="entry name" value="folC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136:SF5">
        <property type="entry name" value="FOLYLPOLYGLUTAMATE SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136">
        <property type="entry name" value="FOLYLPOLYGLUTAMATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="MurD-like peptide ligases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01012">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ25628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="247" mass="26593" checksum="EEE762D3448F9628" modified="2011-01-11" version="1">MATTTGRTYNDAVDALNTLQTPFAVIEARRKAGVRPDEASVKEMRAYLARLGYSISDLDSLNVIHVAGTKGKGSTCAFTDSILARHRAGSPASLPRKVGLLTSPHLIAVRERIRINGCPLSEELFARYFFEVWDRLGESRADEDAVALGTRPIYSRYLTLVSFHAFLREGCDVAILETGIGGEYDATNLVARPVATGITTLGIDHVFALGDTVAKIAWHKAGIMKPGSAAFTVEQVPEAAAVLEAMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q461</accession>
    <name>E3Q461_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7707 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00517</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089393.1">
        <property type="nucleotide sequence ID" value="XM_008091202.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q461"/>
    <dbReference type="GeneID" id="24405882"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00517"/>
    <dbReference type="eggNOG" id="ENOG502S9NN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084512_0_0_1"/>
    <dbReference type="OrthoDB" id="2439692at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056124">
        <property type="entry name" value="DUF7707"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38118">
        <property type="entry name" value="ANCHORED CELL WALL PROTEIN 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38118:SF2">
        <property type="entry name" value="CDP-ALCOHOL PHOSPHATIDYLTRANSFERASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24808">
        <property type="entry name" value="DUF7707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178194" description="DUF7707 domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7707" evidence="2">
        <location>
            <begin position="24"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ25373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="200" mass="20073" checksum="EAEE499C015E6280" modified="2011-01-11" version="1">MPSFKSTFFAVVAAFVATAHADYVIDPSTVSLSTRKSWCQDQTYSCPVICQEVSSNPVEVNTCDPASLTYGCICGNGNQPNMSEYSLTLPFHVCQEYGNQCVAKCGLGANTCANNCRVNNPCGAQNPTRVNVTSTASASASATESANAVFSGIPGSPSSGSGSGSGSGSGSSGAAALEMGRSAGLAVLVGGVVGGLAFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4I8</accession>
    <name>E3Q4I8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Tat pathway signal sequence</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_01147</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ustYa family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ26003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090023.1">
        <property type="nucleotide sequence ID" value="XM_008091832.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4I8"/>
    <dbReference type="STRING" id="645133.E3Q4I8"/>
    <dbReference type="GeneID" id="24406512"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01147"/>
    <dbReference type="eggNOG" id="ENOG502S0D8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042941_0_0_1"/>
    <dbReference type="OrthoDB" id="3687641at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043386">
        <property type="term" value="P:mycotoxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365:SF14">
        <property type="entry name" value="TAT PATHWAY SIGNAL SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365">
        <property type="entry name" value="YALI0B05434P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ26003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="294" mass="34455" checksum="DEC9735B876C0A70" modified="2011-01-11" version="1">MKDLYQSVPDQDSSEDLSNEEKWASPRPETRDQWSFRSRLITALNAVFFVASCGMLFISWRWLDDPIRLMKRVSPYSPILDSLPIKLETVEVKGTLFNDYTPPRIWRRPPSEEVDKAWDDVARIEYFGVSGEALRKMGKDPEISVSIPEEWGVGPDKYLVEIDMQHQLHCLNAVRKYAYWDYYYGDSYRNISMAPKRHQAHLEHCIDILLQALTCNPSLDLISHNWMRTQENPYPDFNIKRQCVAHDPILKWQHENGITEQIMKYKNLPRPEKFPEVEPEPSILLIGEDLGHHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4J4</accession>
    <name>E3Q4J4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioesterase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_01153</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ26009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090029.1">
        <property type="nucleotide sequence ID" value="XM_008091838.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4J4"/>
    <dbReference type="GeneID" id="24406518"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01153"/>
    <dbReference type="eggNOG" id="ENOG502S3GI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066049_0_0_1"/>
    <dbReference type="OrthoDB" id="10253869at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="333" mass="36096" checksum="AD901DEFD64AEAF9" modified="2011-01-11" version="1">MLYHPAPKECELVQPASPRGETQMPLILVHDGGGTTFAYHCLGPLDRAVFGIANPRFHSGVPWDGGLPEMAATYLRMIRATVTKGRDYPAQAPRSPPPPRSSRGGGGKPRRRILLGGWSLGGMLSLEIARQLGDEDEDIEIAGLVIVDSVYPVWPEGLRVKIGRLVDGPEPETKNLRLARRAMGMAGGMVRAWKIPRCGAAAAAAAAVTVPRMAGGGDVDDRENHGDGDHGGLDTGFYGSKREKETAEVVWERPPRAVLVKAKARVPSSTAGVISSVDVYREDEKLGWDGYCPGFVERVLMTEGHHFDMFDWGHIDGITEKIFEACRVLERAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5E3</accession>
    <name>E3Q5E3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_01054</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089930.1">
        <property type="nucleotide sequence ID" value="XM_008091739.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5E3"/>
    <dbReference type="STRING" id="645133.E3Q5E3"/>
    <dbReference type="GeneID" id="24406419"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01054"/>
    <dbReference type="eggNOG" id="ENOG502SP5N">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024934_5_2_1"/>
    <dbReference type="OrthoDB" id="5295362at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052400">
        <property type="entry name" value="Zn2-C6_fungal_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47657">
        <property type="entry name" value="STEROL REGULATORY ELEMENT-BINDING PROTEIN ECM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47657:SF7">
        <property type="entry name" value="STEROL REGULATORY ELEMENT-BINDING PROTEIN ECM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="44"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="86"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="89"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="153"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ25910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="512" mass="56486" checksum="D85963C47EFA8128" modified="2011-01-11" version="1">MNGTPQTASLKNEVAALESSNHRPKAASPAVRGTRIGHKKSRNGCQQCKKRRVKCDESRPCRNCARHDVQCSLIMTPFSAHLLPVSEPSPKSTLEAANTATPDSVGEASTTSRPESRPETSPPQLSSLKEKVAAIQGLLSEFSAEVDALHHTERHSFSEPAHDSTATQGESRDAQGVSRTDWMIDMQLVHHFTSNTAHTISENPDFVHLWTTTVPQIAFANDFLLHGILAVSAIHVAHCYPEKRVEYATISARHQNVALGKFSPGLAEIDEKNADAYVLHAICIFILNTYFIANPSGPIVPRDVAQSFILLQGIQSILALPFAHKRISNGPLARWLYQGGVEPAVAGNFSAKIDDLINLTRSMAPSEDTTTCQSALEGLKITSTAVSMPQHRSGLVWRWAISLPQSFLELISQNHPMALVILMYYAALVHALERDMWYLCGWGSNVASSLEKAIQEPWREWIQWPLGCIRDGTDIRRVAPFKPVPVEALPRPQLPVVNFNLDFLFKSREPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5E5</accession>
    <name>E3Q5E5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TLC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_01056</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sphingosine N-acyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089932.1">
        <property type="nucleotide sequence ID" value="XM_008091741.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5E5"/>
    <dbReference type="STRING" id="645133.E3Q5E5"/>
    <dbReference type="GeneID" id="24406421"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01056"/>
    <dbReference type="eggNOG" id="KOG1607">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1547433_0_0_1"/>
    <dbReference type="OrthoDB" id="537032at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050291">
        <property type="term" value="F:sphingosine N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016439">
        <property type="entry name" value="Lag1/Lac1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560:SF0">
        <property type="entry name" value="LD18904P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560">
        <property type="entry name" value="LONGEVITY ASSURANCE FACTOR 1 LAG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="7">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ25912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="173" mass="19921" checksum="80F1C2201CF2CBF8" modified="2011-01-11" version="1">MDVIELIFLLAKCLKYVGFTTLCDVVFGVFLCVWAWTRHVFYLMVCWSVYYDLLRSLEQLCFWGAAEDVGFLTFLLALEVVICVWSFLIIWVIIRVLKGASAEDVRSDVEEEEEEEEVQVVEDVGVDSIDLKAWERRTAKRTSGLRASGVSIHLSQSDRKELLNRIGCEKQIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5G7</accession>
    <name>E3Q5G7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sugar transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_01078</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089954.1">
        <property type="nucleotide sequence ID" value="XM_008091763.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5G7"/>
    <dbReference type="STRING" id="645133.E3Q5G7"/>
    <dbReference type="GeneID" id="24406443"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01078"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_13_1"/>
    <dbReference type="OrthoDB" id="6133115at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF64">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="205"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="277"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="306"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="1"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ25934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="374" mass="41338" checksum="ABC48AF7EAD2DAB9" modified="2011-01-11" version="1">MGWNLKLVNSDDRHALESTTPTTTKTVSTVLMTELAYPAHRATATALSSTTYSVGAILAAWVAFGSFRIQNTWAWRTPTMIQAVPSAMVLCRLLFLPESPRWLWSKGKEQTALEILTKYHGAGNVDDVVVQHRYAEIRDTIEAEISQNKNPFHLKALFSTPGNRWRSFIIIWCGICKQWSGNGLISYFLGSMLKSAGITRQIETTLVTATSTAGMWVVFVVITATTGAYVEAGNRHASFTTVAFIYLYSGVHNLGWKGAQMLYIVEILPYTIRAKGMAMFSLVAGICGAFSTYVNPLGIAAISWKFYFFYVAWIIVQFVVVYLVFPETKGPSLEQVALLFDGNDAQVGRINAVANKMLDEKGGGFAVKMRDNSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5X8</accession>
    <name>E3Q5X8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phospho-2-dehydro-3-deoxyheptonate aldolase</fullName>
            <ecNumber evidence="6">2.5.1.54</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_01370</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>D-erythrose 4-phosphate + phosphoenolpyruvate + H2O = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14717"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="2.5.1.54"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the class-I DAHP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.54" evidence="6"/>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090246.1">
        <property type="nucleotide sequence ID" value="XM_008092055.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5X8"/>
    <dbReference type="STRING" id="645133.E3Q5X8"/>
    <dbReference type="GeneID" id="24406735"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01370"/>
    <dbReference type="eggNOG" id="ENOG502QPSU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030903_0_1_1"/>
    <dbReference type="OrthoDB" id="4699125at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003849">
        <property type="term" value="F:3-deoxy-7-phosphoheptulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000005">
        <property type="entry name" value="Phospho-2-dehydro-3-deoxyheptonate aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006219">
        <property type="entry name" value="DAHP_synth_1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00034">
        <property type="entry name" value="aroFGH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009395">
        <property type="entry name" value="PRK12755.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21225">
        <property type="entry name" value="PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE DAHP SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21225:SF18">
        <property type="entry name" value="PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE, PHENYLALANINE-INHIBITED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001361">
        <property type="entry name" value="DAHP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4 6" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAHP synthetase I/KDSA" evidence="7">
        <location>
            <begin position="57"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR001361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ26226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="375" mass="40781" checksum="57483D131BCC481D" modified="2011-01-11" version="1">MSSFFIENKNVGNKAESEDWRIRGYNPLTSPDLLQHEIAQTTKSKQTVLQGREEAVAIVNGTDEKERLLVIIGPCSIHDPKAALEYCDLLLQAKEKHKDELLIVMRSYLEKPRTTVGWKGLINDPDIDNSFKINKGLRMSRQLFVDLTDKGMPIASEMLDTISPQFLADLLSVGAVGARTTESQLHRELASGLSFPVGFKNGTDGSLGVSIDAIGAVRHPHHFLSVTKPGVVAIVGTVGNEDCFTILRGGTRGTNYDAKSIAEAKAALEKAGLPQRLMVDCSHGNSLKNHKNQPKVAADLAGQIAGGETGIMGVMIESNINEGNQKVPKEGKEGLKYGVSITDACIHWDDTVTVLDQLADAVKQRREVLRRNGHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6U4</accession>
    <name>E3Q6U4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">galacturonan 1,4-alpha-galacturonidase</fullName>
            <ecNumber evidence="11">3.2.1.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">GLRG_02402</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>[(1-&gt;4)-alpha-D-galacturonosyl](n) + H2O = alpha-D-galacturonate + [(1-&gt;4)-alpha-D-galacturonosyl](n-1)</text>
            <dbReference type="Rhea" id="RHEA:14117"/>
            <dbReference type="Rhea" id="RHEA-COMP:14570"/>
            <dbReference type="Rhea" id="RHEA-COMP:14572"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58658"/>
            <dbReference type="ChEBI" id="CHEBI:140523"/>
            <dbReference type="EC" id="3.2.1.67"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the glycosyl hydrolase 28 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.67" evidence="11"/>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090602.1">
        <property type="nucleotide sequence ID" value="XM_008092411.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6U4"/>
    <dbReference type="STRING" id="645133.E3Q6U4"/>
    <dbReference type="GeneID" id="24407767"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02402"/>
    <dbReference type="eggNOG" id="ENOG502QPPR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016031_1_0_1"/>
    <dbReference type="OrthoDB" id="187139at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047911">
        <property type="term" value="F:galacturan 1,4-alpha-galacturonidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004650">
        <property type="term" value="F:polygalacturonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000743">
        <property type="entry name" value="Glyco_hydro_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31736">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31736:SF14">
        <property type="entry name" value="EXOPOLYGALACTURONASE X-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00295">
        <property type="entry name" value="Glyco_hydro_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00502">
        <property type="entry name" value="POLYGALACTURONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 14" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 14 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="active site" evidence="13">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EFQ26582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="313" mass="33652" checksum="8A605CABAF2DBD16" modified="2011-01-11" version="1">MWKIGGTDVNIYGNGAGTLNGNGQKWYDRFAFNATLQRPILLVTDGLHGGSITGLNMVNSPQWFNLIANSSNVLVSDITIKVGSISKNPAKNTDGCDTYRSDSVVIQNSHIDNGDDCVSFKPNSTNIVVQNLVCNGSHGISVGSLGQYVGTFDVVENLYVYNTTMSNASDAARIKVWPGIDTPFQPSLSGGGGSGYVRNVTYDGFHNSNNDNVITIDQCYGQKNQTLCNQYPSNLTISDIYFKNFDGTTSSKYSPRVGTLVCSSPAKCLNINASKIDIETPTGANPQWLCVNLDTGLLDINCVTKVTKRSIGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q733</accession>
    <name>E3Q733_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_02491</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090691.1">
        <property type="nucleotide sequence ID" value="XM_008092500.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q733"/>
    <dbReference type="STRING" id="645133.E3Q733"/>
    <dbReference type="GeneID" id="24407856"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02491"/>
    <dbReference type="eggNOG" id="ENOG502SNUJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006524_5_0_1"/>
    <dbReference type="OrthoDB" id="5424793at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF39">
        <property type="entry name" value="TRANSCRIPTION FACTOR PBCR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="23"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="58"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ26671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="645" mass="71793" checksum="63AC209B0A990655" modified="2011-01-11" version="1">MESIIDADASGARATLRQRVTNACEACRVAKVKCQTGIQPGICQRCLEFKRECIFRTGPRTRRPRQSRLNQDAPRPPPPPGPSKTFSIDFGMPQLEEPDDFETIAAQHERYFEELIPLSDPESINIMLGLEDPGSGPYSTISTPPSSGSGPSISVSNLGLKPQFNLDSAEKLLQTFRAMLKHFPCVALPPDATVMSLSKTKPFLLLAILSTASASSALQGHTLYDEEFRKILGLKFVAGSERTLELLQGLLIYTAWYPFHLRPKSKQGFHYVRMAAEILHDLGLDHPPYQNAGVSTPPIADQMEGIRAYLSCYYLVTAHVLPYLQMSPARLPYTSWTGTCCDLLERSSALKGDHTLAWLARLLHITEEASEMMKNAPATEQAKQQAHFMFLGLDSQLREWQNQLPSSLGDVNSIKIATLFTEIFLLAGPIYRLASTSKMGDPFLGPPIPAPRLERCLVLLRSFFDFTVNLDKTAFLEMSCIDWCRFIQVVIVAVRVSFPLPLCPEWDHARAREQLQFDSYLAKLSAHHEELTPSTKSMDVYSASQVVFAVIKRKYEGRMANICAPVNQLPRSIRGCPMFDGSLDPYFPIWDQDINLTGAHGLVPPVLNGTTTAVNGQDLYNDLWATMTMGPEEMNGDSDQGFDLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q743</accession>
    <name>E3Q743_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_02501</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090701.1">
        <property type="nucleotide sequence ID" value="XM_008092510.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q743"/>
    <dbReference type="GeneID" id="24407866"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02501"/>
    <dbReference type="HOGENOM" id="CLU_2026550_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ26681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="122" mass="13824" checksum="C4E7372F9B9DE4D1" modified="2011-01-11" version="1">MANDKMYDVLPGRESAVYDGTKGNEAPHVASEKAINMDDEPAFLENSPTNMLITRVIQTSTSCNADPLRMMEEMWWFTVARIEVDPVQQPTDSTVWQGSRLVLTNMKTYIFVSFLTQSPLFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7A3</accession>
    <name>E3Q7A3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteophosphoglycan ppg4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02561</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090761.1">
        <property type="nucleotide sequence ID" value="XM_008092570.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7A3"/>
    <dbReference type="STRING" id="645133.E3Q7A3"/>
    <dbReference type="GeneID" id="24407926"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02561"/>
    <dbReference type="eggNOG" id="ENOG502SWU4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004293_0_0_1"/>
    <dbReference type="OrthoDB" id="5341904at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="450"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="601"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="660"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="872"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="896"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="997"/>
            <end position="1110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="68"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="457"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="498"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="561"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="912"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="927"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="957"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1001"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1025"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1069"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1085"/>
            <end position="1094"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1132" mass="123397" checksum="B82A01ABBDCA3F46" modified="2011-01-11" version="1">MGNTHSIVSPHYEEDPDESNNKRPPQKLSKPRVGNHGRSGSSSLPPSRSNSHAFRARSSAPSPVQALSESQASAPVAAEAPSPAAKPEPRPAKNWKRRASLFRSKSSQEPRTERRRDSVTTSPTLPDRMSRANSMTWETQQEMNTSRQLQVESWHMPGNRQSINYNLMSYESRRLLNLTEDLTACEEGSIMSESKFEVSPSTWKSSHPTQPAIPKLPRADSEVSLYAPVRRRSIIQTPGLATRLPTDYSASRRSSLRYSVATTPACGHSRLNSIESSTYPTLQPLTDSLTDFFSEPDYMPAPSTEPIERALTPSDMDYRPLGTMKFGSLRITNGAASPLPSPDLEPEAKAEVTEKLHNGKEEYFIRDVGLGGSRSNDKDVEMSVSAVHASTALSPINTSFLRVESRSQRSNSPLSPELQTTSKHTALEDELFEDDDVQLEYSAEVLTVRNDPNAKPSLERLRSEQSKRTSQAIVRTDSGVVASPTTEQPKLLSKADSGYSSNVSLRSFHTKQSAVKGGQRRSTASDDSGDEQSDGAVSLTAAVANKSPIAGPPTADDGLATGTTQPLSATSPSPQPKGDFVVPPKSPAALSPKFFFNLNTGHSFRKDRKGPVTVDSAKPAKQGPMSPQSTPPGDASPDKPASVLSIGTGPQRVGKFQRFMNGSSLRGPPAVHTTHPSDKPVPSVPQDVQAKLGQHSERFPTATTRLTLRPQASKDTLNTIMSVGSVFPGHADANQGPLLSAGVSQVTKDPVDETPEPFENPKTPMRRSFQSVPASIAHAAASALPRLSINRKPLSRTPKAGKEFTGEANADEIQVGFESDITAMGNVGDSAGNGAFYQAFLALPSQQPAHSPRERTMTLTAEMERGMRRSFYPAESTSPTPQQAVLRAPRHSQFMDVTAKRRSSPPISLHTRNSKNTRKQAPRPKSAHSSQTTPSTRRPALPQEASRETFHSYPSTSAAALDDALSAPPIPPMSPRRGMAMLEQRYTMRRMSVENKWRPTNGWSADSNQGVRPVSQGSATSVGHQSQQQQQQQQLQQLLRHRSSYDSYSQHRGPVARGPAAASQGGGYYQQQLMEIQQQQWQQQRRNSSDTVQPGLSRGHIRSRSMHANGHPPFRVLHSYNSPAYRNVPIWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7Y6</accession>
    <name>E3Q7Y6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_02169</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ26998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091018.1">
        <property type="nucleotide sequence ID" value="XM_008092827.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7Y6"/>
    <dbReference type="STRING" id="645133.E3Q7Y6"/>
    <dbReference type="GeneID" id="24407534"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02169"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1137906_0_0_1"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF22">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="56"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ26998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="244" mass="26040" checksum="0F6C6875EB8DBF62" modified="2011-01-11" version="1">MVVTTHNNGSGAEKDGLHTKHVELGTDTQLAQAAGLEDHELGIWKSLVRYPWASAWCVYACWTIILLSFDLQAAGAVVGIPTFRRDFGYEFEGDYVLPAAWQSAFSGAPVATAVVSSIASAELADFIGRKKVLAIALLISFVAVAIEFIATTNAVFFAGKLLNGFMVGALGTIMISYIGEITPLALSGIFTCGVGVAYGVGPLVAFIIINYTGTSQSRWAYRTVFCCQFGFAGVSAILWPFMPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8V1</accession>
    <name>E3Q8V1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Enoyl-CoA hydratase/isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_01960</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091485.1">
        <property type="nucleotide sequence ID" value="XM_008093294.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8V1"/>
    <dbReference type="STRING" id="645133.E3Q8V1"/>
    <dbReference type="GeneID" id="24407325"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01960"/>
    <dbReference type="eggNOG" id="KOG1679">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_7_6_1"/>
    <dbReference type="OrthoDB" id="410701at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016836">
        <property type="term" value="F:hydro-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000058">
        <property type="entry name" value="Enoyl-CoA hydratase/isomerase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.12.10:FF:000001">
        <property type="entry name" value="Probable enoyl-CoA hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="entry name" value="Lyase 2-enoyl-coa Hydratase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF171">
        <property type="entry name" value="SD19268P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ27465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="342" mass="36576" checksum="07069755BCA81910" modified="2011-01-11" version="1">MPPRLTPLRVAIRIPRTTIVSSKSAAAAAFYSTSTASDSNQPLITVTQLPAPGSGHIRILELNRPKARNALSKALLSQLRAEIDAIHAQYDPETGDELPQKAVFGGAAGKDVKGPTRALILASAVETSFCAGADLKERRGFTQQETDEFLHNLRSTFTSLQNLPIPTISAISSIALGGGLELALSTHFRVLSSNAQVGLPETRLGIIPGAGGTHRLPALIGLSRARDLILTGRRVSAPEAYFLGIADRLVDITHEEAEKAGEGDKDKGVLLVARKAALSESVRLAGEICEGGPIAIRAALQAVAWAREEVENKMYERVVATEDRNEALKAFQEKRKPVFKGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q911</accession>
    <name>E3Q911_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02020</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091545.1">
        <property type="nucleotide sequence ID" value="XM_008093354.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q911"/>
    <dbReference type="GeneID" id="24407385"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02020"/>
    <dbReference type="eggNOG" id="ENOG502T392">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038594_0_0_1"/>
    <dbReference type="OrthoDB" id="4824845at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="349"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="521" mass="57608" checksum="A53692CA1619A742" modified="2011-01-11" version="1">MYSFMPRRNVEGPVSHAKWPSTESFRSPASPWEVDDSTAQTVSRLNWVFGFRPPTGYAKSSPGASPDDLSRYSPELPHLLADRTPELRHDTPSDARTRTSSFGPETPPTKADSYFSSEPLVQPLTPVRTSNYHLRSRSDSCSLQSFYSESQYRIGAESTAAIGHDAKQHPYHDPMSRSGDISPNKQSRETSSTHQNYAVALTRNNRAVTLILTAGNPAQSGQPNITCYRQTSLPLGGPFAEFFKASEALALLQHMVNASSMSYQPFSKRERSELLLRMRTSDEGMILGNPCSNARAWTSFFSTELAAGRAWEAGTVIFPWKVLEKLMSSLNAEFARKRKIQARAVVRREMDEHPGARGPPPFQHGYGRSPDTRPTSLLLACDSSISSAPMSGAAGSDRCSVSSASPPPPGTPTEVLPPKLQLVSERAKSPPTQLRCRRQKSEPVRPLSLAPPRIALLKPKACRQSLRGLHSASTPVRLEFYDSIRQWPASSHRAQVRLPPCSRFLEMVENQEPKPRNSIVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9H4</accession>
    <name>E3Q9H4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_01848</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091373.1">
        <property type="nucleotide sequence ID" value="XM_008093182.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9H4"/>
    <dbReference type="GeneID" id="24407213"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01848"/>
    <dbReference type="HOGENOM" id="CLU_1927440_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ27353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="131" mass="14056" checksum="84D9F4C819B42400" modified="2011-01-11" version="1">MLRAAQKGLQHRHVICRGVVFLSYVVSVELAKDDFGGQSLVAGSGVALELGWDDIVDIVMLDGVSSGVGTDSCGYAIKAQRRQTVTENPGEVAVGGGTYPGKQEPSRKLLVDYVPAPAGTYFGRYEKDHHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9X7</accession>
    <name>E3Q9X7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Synaptobrevin homolog YKT6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_02809</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the synaptobrevin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091685.1">
        <property type="nucleotide sequence ID" value="XM_008093494.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9X7"/>
    <dbReference type="STRING" id="645133.E3Q9X7"/>
    <dbReference type="GeneID" id="24408174"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02809"/>
    <dbReference type="eggNOG" id="KOG0861">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074848_0_1_1"/>
    <dbReference type="OrthoDB" id="27923at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000421">
        <property type="term" value="C:autophagosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033106">
        <property type="term" value="C:cis-Golgi network membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016409">
        <property type="term" value="F:palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061909">
        <property type="term" value="P:autophagosome-lysosome fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042144">
        <property type="term" value="P:vacuole fusion, non-autophagic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd14824">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15867">
        <property type="entry name" value="R-SNARE_YKT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000020">
        <property type="entry name" value="synaptobrevin homolog YKT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.50">
        <property type="entry name" value="Longin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010908">
        <property type="entry name" value="Longin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045848">
        <property type="entry name" value="R-SNARE_YKT6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042855">
        <property type="entry name" value="V_SNARE_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45806">
        <property type="entry name" value="SYNAPTOBREVIN HOMOLOG YKT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45806:SF1">
        <property type="entry name" value="SYNAPTOBREVIN HOMOLOG YKT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13774">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00957">
        <property type="entry name" value="Synaptobrevin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01270">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50859">
        <property type="entry name" value="LONGIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50892">
        <property type="entry name" value="V_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0488">Methylation</keyword>
    <keyword evidence="5" id="KW-0564">Palmitate</keyword>
    <keyword evidence="7" id="KW-0636">Prenylation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Longin" evidence="10">
        <location>
            <begin position="7"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="V-SNARE coiled-coil homology" evidence="11">
        <location>
            <begin position="137"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ27665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="197" mass="22360" checksum="063CD0EEC3515AA2" modified="2011-01-11" version="1">MKLHYIGILRNDSKPAVELCSEMELSAYSRFTRGSYAEFMTLFSKKVAESTRPGQRQDIEEGDNTFHCVGRSEGICGVIISDHQYPSLVAHQLLSKIVDEFLTKHPRSTWATGEPKLALPELKEYLTKYQDPQQADSILKIQKELDETKIVLHKTIQSVLERGEKIDDLVAKSDGLSSQSKMFYQQAKKQNSCCIVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>E3QB86</accession>
    <name>E3QB86_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_03268</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ28124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092144.1">
        <property type="nucleotide sequence ID" value="XM_008093953.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QB86"/>
    <dbReference type="GeneID" id="24408633"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03268"/>
    <dbReference type="HOGENOM" id="CLU_2413130_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ28124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="92" mass="10194" checksum="B90D9508DF1B0E8E" modified="2011-01-11" version="1">MHTNLRIAQQKPSFNTTALLPELRAASAVSVEEPRFDDVWRFATSAICSPTQSQLKPRLFLCLLLLPSSHSIAIRKPTSSDIPMANLSQSML</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBA8</accession>
    <name>E3QBA8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dynamin GTPase</fullName>
            <ecNumber evidence="3">3.6.5.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">GLRG_03290</name>
    </gene>
    <organism evidence="22">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="17">Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.5" evidence="3"/>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ28146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092166.1">
        <property type="nucleotide sequence ID" value="XM_008093975.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBA8"/>
    <dbReference type="STRING" id="645133.E3QBA8"/>
    <dbReference type="GeneID" id="24408655"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03290"/>
    <dbReference type="eggNOG" id="KOG0446">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008640_0_0_1"/>
    <dbReference type="OrthoDB" id="5061070at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030061">
        <property type="term" value="C:mitochondrial crista"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097002">
        <property type="term" value="C:mitochondrial inner boundary membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901612">
        <property type="term" value="F:cardiolipin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140523">
        <property type="term" value="F:GTPase-dependent fusogenic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0180020">
        <property type="term" value="F:membrane bending activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070300">
        <property type="term" value="F:phosphatidic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080025">
        <property type="term" value="F:phosphatidylinositol-3,5-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001786">
        <property type="term" value="F:phosphatidylserine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042407">
        <property type="term" value="P:cristae formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015886">
        <property type="term" value="P:heme transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097753">
        <property type="term" value="P:membrane bending"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097749">
        <property type="term" value="P:membrane tubulation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990627">
        <property type="term" value="P:mitochondrial inner membrane fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990626">
        <property type="term" value="P:mitochondrial outer membrane fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000001">
        <property type="term" value="P:mitochondrion inheritance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031623">
        <property type="term" value="P:receptor internalization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000741">
        <property type="entry name" value="Putative mitochondrial dynamin GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019762">
        <property type="entry name" value="Dynamin_GTPase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020850">
        <property type="entry name" value="GED_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056495">
        <property type="entry name" value="LIS_MGM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF212">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24550">
        <property type="entry name" value="LIS_MGM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00410">
        <property type="entry name" value="G_DYNAMIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51388">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13 17" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="6 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="20">
        <location>
            <begin position="238"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="GED" evidence="19">
        <location>
            <begin position="803"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="161"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="897"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="18">
        <location>
            <begin position="162"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="897"/>
            <end position="916"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU003932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EFQ28146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="922" mass="102139" checksum="E313CE1A53415BED" modified="2011-01-11" version="1">MSGRLLAAGLSPSTRRAPVQAVRHFHRFPAGGLQRADAAIRATQRRMWFPGNAFHNAVIVRNASFARFLPKLVVKFARIPAMFGGLAVGTLAWIQYQANQITNNAWDMVTKTADGVSETASSFFGGAKGIVDQTMRGWENTKEQIETPEWLQKVLRIHDDIGTGGGGSEGPGGEQPKQSRAGAAVVAGGSAAAYGYDQSSEDDPREPDEVARDDQMMVLTKKMIEIRGMLQQVGQSSTLTLPSIVVIGSQSSGKSSVLEALVGHEFLPKGTNMVTRRPIELTLVNTPESEAEYGEFPDLGLRRITDFSSIQRTLTELNLAVPDAQCVSDDPIHLTIYSPNVPDLSLIDLPGYIQVVGQGQPLELKQKISELCDKYIQPPNVILAISAADVDLANSTALRASRRVDPRGERTIGVVTKMDLVDAPRGAAILGDKQYPLRLGYVGVVSKVPQTGGLFKRSGSVMSAIAKNESTFFSAHPLEFGEGAGVSVGTINLRKKLMTVLEQTMSASLATTSDAIRQELEEATYEFKVQYNDRPLSAESYLAESLDGFKHSFKQFTEEFGRPQMHQLLKQELDQKVLDLLAARYWNKPIQDLSPTGPEPDSLADLPKADPDSLYWRRQLDASTSSLTKLGVGRLATTVVASAIQAHIDTLIKHSTFSNHPFAREAINEAASTILNERFYSTSDQVENCIKPYKFEIDIDEREWTQGRDHSAVVLKKELQDCEGALKSIEDTVGGRRKLREVMNFVDRARKGEIVVEGESRSGAGGFSASLLKRGREAVFLRDRADIIKMRLMAVKSKQCANLKNKYYCPEVFLDAAATKLASTAVLFLNVELLSEFYYNFPRELDLRLGRHLSDEDIERFAKEDPKIRRHLEVIRRKELLELVLEKMESLRQLEGRERERLKGGNSRPAKDDKQRGRWGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBU5</accession>
    <name>E3QBU5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tat pathway signal sequence</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_03324</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092200.1">
        <property type="nucleotide sequence ID" value="XM_008094009.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBU5"/>
    <dbReference type="STRING" id="645133.E3QBU5"/>
    <dbReference type="GeneID" id="24408689"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03324"/>
    <dbReference type="eggNOG" id="ENOG502RUV2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037358_2_1_1"/>
    <dbReference type="OrthoDB" id="7984201at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051057">
        <property type="entry name" value="PI-PLC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593:SF146">
        <property type="entry name" value="PLC-LIKE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26146">
        <property type="entry name" value="PI-PLC_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179595" description="Tat pathway signal sequence" evidence="1">
        <location>
            <begin position="17"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ28180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="286" mass="32181" checksum="9FF77DEA4A1D712A" modified="2011-01-11" version="1">MLRAARFVSVLAGIAAACCNGNDALCEKKYSDVTFVGSHNSAFVGITPAHNQYVSVTDQLDMGVRFLQAQTQNKNGQIQMCHTTCVLLDSGSLSEYLGDITSWIEAHPRDVVTLLLTNIDAMPVTQFGDTFRDTGLEKYVFRPKEKVALDQWPTLQELIDDGTRLVVFMDYHSDTSKVDYILDEFQYYWETPFGETNADFPNCNIDRPQGVDPNGYMYLVNHFLNIELFAGIKIPDQFNAPKTNSLQSIDKQVNLCRGKWGRTPNVVLLDWIDIGEAIKAQNQYNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCC0</accession>
    <name>E3QCC0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_03652</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092528.1">
        <property type="nucleotide sequence ID" value="XM_008094337.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCC0"/>
    <dbReference type="STRING" id="645133.E3QCC0"/>
    <dbReference type="GeneID" id="24409017"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03652"/>
    <dbReference type="eggNOG" id="KOG0031">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054966_1_0_1"/>
    <dbReference type="OrthoDB" id="429467at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050403">
        <property type="entry name" value="Myosin_RLC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23049">
        <property type="entry name" value="MYOSIN REGULATORY LIGHT CHAIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13405">
        <property type="entry name" value="EF-hand_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="110"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="180"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="38"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ28508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="280" mass="30012" checksum="39208AB4C9C1CB2B" modified="2011-01-11" version="1">MPSSYKPSPLGPHGSPRSSPFRRPESPASPSAARQPSTQVTPFGSPTKASFATNNGRFGNPTTPTDTAEIRTPRVRTPTAETTMVSPLPLRPGLKKAISHGNALSQLQPAQVRQLREGFEILDRDSDGVINREDVASMLSQLGLPSSASDVSQFFPPSAAQTMTMAAFLNSLATMLASLSPQPELLSAFSAFDDDDSGQIDLAELRDALLHTAPEPGERPLTEAEVEKVIEGFTGRRAFNRHMQGGLGNRREVFRYQDFVNSIMGTNTASEAASAEGSED</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCV2</accession>
    <name>E3QCV2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_03868</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092744.1">
        <property type="nucleotide sequence ID" value="XM_008094553.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCV2"/>
    <dbReference type="STRING" id="645133.E3QCV2"/>
    <dbReference type="GeneID" id="24409233"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03868"/>
    <dbReference type="eggNOG" id="ENOG502S1DF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013056_0_0_1"/>
    <dbReference type="OrthoDB" id="5407645at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="354"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="403"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="565"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="626"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="403"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="452"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="479"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="506"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="566"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="650"/>
            <end position="672"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ28724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="702" mass="78397" checksum="379DAA4D7C1C0B7B" modified="2011-01-11" version="1">MSYDYEPPRARRYVREERREERIDPRYADDGYLKVYQSREIIPKARENSDLSIEEVRRDFPPPGYRDSRRTRSAEPGYYDDYRGYDDRDRYYDRDYNRRSRKAGSVLYAEEERSRRRVLNQQEKIIAAVAGAALAFGGKELYDRKEAKEHGGEIERNYLSSAALGAAGALAGYQGAEYYSKRKEKEEDKATYVVHRGRDGRVTEYYSDDEGEREKKSNKSFLENALAASGLGVAVKALTGAGGGDDRRSDTRSRRGSPDSRGSRSKSRGPGGEAASKMQKAAMASLIAGATEAFRVAKEPGGWKGEKTKRIITAAAGAATIDAAQGGEKQSKLGLAESVIGGLLGNRVINGSKRNIEEDRSTGRSRSRSRARSDGGGGGPGLAALATAGLGAFSAKKAIENVRSRSRGRSADSYDSRASSRSRDGRRQRSRSRSVVDSARKKLAKIGLGSDPEEKERDKYARDDSYYDDRSSRRGTSRRYSDEYDDGYTRGGRDAAYEDDRSSYTSRRRDRSRRRGGKSDASSDSDLGDSDDDAKRARKMRGKQVITTGLAAVATIHAAHGVYQSMEKRNARQKAVREGRLSPEEAKKLKTKAIVQDAASVGIAALGIKGAWSELKEAKEMTHECKQFQQEKALRHQKRLERQRRLNNGYDRRRGRADDWYSSESPREDRYDYGSTYYDDNPYTAGRLPAPPASYDDGRYRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDI9</accession>
    <name>E3QDI9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">AMP deaminase</fullName>
            <ecNumber evidence="4">3.5.4.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Myoadenylate deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_03838</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via salvage pathway; IMP from AMP: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.6" evidence="4"/>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092714.1">
        <property type="nucleotide sequence ID" value="XM_008094523.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDI9"/>
    <dbReference type="STRING" id="645133.E3QDI9"/>
    <dbReference type="GeneID" id="24409203"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03838"/>
    <dbReference type="eggNOG" id="KOG1096">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003782_0_0_1"/>
    <dbReference type="OrthoDB" id="1723809at2759"/>
    <dbReference type="UniPathway" id="UPA00591">
        <property type="reaction ID" value="UER00663"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003876">
        <property type="term" value="F:AMP deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046033">
        <property type="term" value="P:AMP metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032264">
        <property type="term" value="P:IMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01319">
        <property type="entry name" value="AMPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.800.20:FF:000001">
        <property type="entry name" value="AMP deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000214">
        <property type="entry name" value="AMP deaminase Amd1, putative (AFU_orthologue AFUA_8G02860)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000035">
        <property type="entry name" value="Probable amp deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.800.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006650">
        <property type="entry name" value="A/AMP_deam_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006329">
        <property type="entry name" value="AMPD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01429">
        <property type="entry name" value="AMP_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11359">
        <property type="entry name" value="AMP DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11359:SF0">
        <property type="entry name" value="AMP DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19326">
        <property type="entry name" value="AMP_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00485">
        <property type="entry name" value="A_DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="95"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="199"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="260"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="909"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="105"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00072037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00078830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ28694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="947" mass="106197" checksum="52E607A278F47E8B" modified="2011-01-11" version="1">MLPRDLPTRTAFYDPVAERQMSQTDAKLFYQRSQIGQLKTGSGVWSQGHSTPPHGSPVIVGSEHRDIPAGPRGLEYPVDSSPLAKERTISKGKAAAHEGAMLPEPTQQRFGQTTDLESLPPPRYHPLRDGPEPLGNRGPAANVGLDHNTDSNVRAPNHPALGVAAFSDTDPHITAELSAISKNIQSIMDLRERYIGLSLQGPDDNPRDDPSWSIYPPPPQPAWGAEHARAVAPGEHHVSTSNSLTGSMVLPPAADDLAGRQVPGVESKPTAKKRKPGQDIGEDFKMDDLLPLPSADKTRFKLDDSGVYQVFEDEAAEASGNPVIMVPTIREFYMDLDQILSISSDGPSKSFAFRRLQYLEGKFNLYALLNEYQETADSKKVPHRDFYNVRKVDTHVHHSACMNQKHLLRFIKSKMKKYPDEVVLYRDDRHLTLAEVFQSINLTAYDLSIDTLDMHAHTDSFHRFDKFNLKYNPIGESRLRTIFLKTDNFINGRYLAEITKEVIADLESSKYQMVEWRISIYGKSLDEWDKLAAWVVDNKLFSHNVRWLIQIPRLYDVYKASGLMDTFEQVVKNVFEPLFEVSRDPSSHPKLHVFLQRVIGFDSVDDESKVERRLFKKFPVPKVWDSKQNPPYSYWIYYLFANMSSLNALRKRRGFNTFVMRPHCGEAGDSEHLAVALLCCHSISHGLLLRKVPLLQYIFYLEQIGIAMSPLSNNALFLAYERNPFYQYFRRGLNVSLSTDDPLQFAFTKEPLMEEYAVAAQIYKLSPVDMCELAKNSVKQSGFESAIKEQWLGPNFKLPGKAGNAMVKTNVPDRREEFRYQTLREEHDMLHKYIAYGAKGSSDSTVTADQQSVAQSIIGGHQSAVLREHTNTGSEPAATIASDVRNEKAAWSGNVGNAAVPENDVVASPASLTPSIEGPWPANAHTSGQDPKLFPGVFSRGQVGSNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDR8</accession>
    <name>E3QDR8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Haloacid dehalogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04150</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093026.1">
        <property type="nucleotide sequence ID" value="XM_008094835.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDR8"/>
    <dbReference type="GeneID" id="24409515"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04150"/>
    <dbReference type="eggNOG" id="ENOG502S0RM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_3_2_1"/>
    <dbReference type="OrthoDB" id="444127at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051540">
        <property type="entry name" value="S-2-haloacid_dehalogenase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01493">
        <property type="entry name" value="HAD-SF-IA-v2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43316:SF9">
        <property type="entry name" value="ACID DEHALOGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43316">
        <property type="entry name" value="HYDROLASE, HALOACID DELAHOGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="239" mass="26932" checksum="98A79E3717986A71" modified="2011-01-11" version="1">MTSLKDFRVLTFDVYGTLIDWETGVLAALQPLLEENQRTDFSRRHLLEVHQDHEYKQQTKTPELPYSELLTTIHPQIADKLGLAAPSPESSKAFGDSVGRWPAFPDTVDALRRLGKYYKLVVLSNVDRESFAATNSGPLAGVPFDLVITAQDVGSYKPDQRNFEYMLAKVKGNFGVEKDQVLQTAQSQFHDHHPAKEAGIKSSWIVRPGAVMGNREREVYDWKFDTLGHMADALEKELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QE18</accession>
    <name>E3QE18_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phospholipid metabolism enzyme regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_04250</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093126.1">
        <property type="nucleotide sequence ID" value="XM_008094935.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QE18"/>
    <dbReference type="STRING" id="645133.E3QE18"/>
    <dbReference type="GeneID" id="24409615"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04250"/>
    <dbReference type="eggNOG" id="ENOG502QU5B">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010147_0_0_1"/>
    <dbReference type="OrthoDB" id="1204at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070772">
        <property type="term" value="C:PAS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010513">
        <property type="term" value="P:positive regulation of phosphatidylinositol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903778">
        <property type="term" value="P:protein localization to vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000011">
        <property type="term" value="P:vacuole inheritance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024260">
        <property type="entry name" value="Vac7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28258">
        <property type="entry name" value="VACUOLAR SEGREGATION PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28258:SF1">
        <property type="entry name" value="VACUOLAR SEGREGATION PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12751">
        <property type="entry name" value="Vac7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="633"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="476"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="711"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="827"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="258"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="376"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="430"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="492"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="504"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="542"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="725"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="740"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="832"/>
            <end position="852"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ29106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="861" mass="92011" checksum="712246D14E3E8F43" modified="2011-01-11" version="1">MEKTSSTANGSSDASQSQLENARTVVAPPSHITTTTEPQSHSKESSATTSLTPSPHNSRDTSPSRQPSRPTIAPKSSSTPGLRSRKSSQQDLTAVRTPRSSSSIPGPPASSRVLSAATTPTLLPNSQESFLKSINPQKVPLSIEVTQTRDSPRWPVSPRLRSPPPQLNKPQNPPAPRRSEQDTPRINLTRASPSPQPDPLPSMSGSETDDSQLPSGVRTPVTANGSALETVQEVSLPNSPGQMDSTLEKVNEKLAQEAAASADNLHADANQTIRRSRGPLQAAETGDNGTLKGRSQSSAPAPNVTRQPSMLSNKQGKGKAAGEGSSLIVETETVSSIPQVALAPASKLEAGGGTLKAKPSTETIRPKKEKKRTSRKQPTVNSSNASSKADIFEAKVASAVDEANTSDSEETFVYDSNPPDVGDRRRFHSRTPSATSMVSQADRPGGMGMRSIHEALQGGAAAAGLKKSMKFVNTFNGNGPESLGTDEDGKGSGRSVGPGSGRGTTRHHHHNHFGRWGRQPGNSHPSLFDNESLFPNAARSKLSGNTSRHSSGPPSPRVASSSRGGPHALGKRSSIQMARYDADDTTTTGADDERTPLISSTVRSARRSRRQPTNLRNLESQAYRQQPSYLNRFAACLVVTMMLLLVITGAIGFMFATSQPLTDIQLVSIKNVLTSDPELMFDMTVKAHNPNIVVVSIDQANLEIFAKSPRAGTDSDWWRRPHGRNKGDLDDPEMHIRDDPPDDPPDDDTAPNMRLGTITEFDSPLSFEGSFFNKGVSASTGTMRLHLPGNHSAGGSERWGRIIQDEFDLIIKGVVRYSLPLSQRVRSAPISGRTTVKPNSANDPSLRPNTTLPGEVPGLEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QE85</accession>
    <name>E3QE85_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA-binding WRKY domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_04317</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093193.1">
        <property type="nucleotide sequence ID" value="XM_008095002.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QE85"/>
    <dbReference type="GeneID" id="24409682"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04317"/>
    <dbReference type="eggNOG" id="ENOG502RGVU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020424_1_0_1"/>
    <dbReference type="OrthoDB" id="3340520at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010775">
        <property type="entry name" value="DUF1365"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33973">
        <property type="entry name" value="OS07G0153300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33973:SF4">
        <property type="entry name" value="OS07G0153300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07103">
        <property type="entry name" value="DUF1365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="17"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="548"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ29173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="642" mass="71463" checksum="ABD3192B7ABBE5BF" modified="2011-01-11" version="1">MSAANLSLRPLTLLVGFAYYSLLGGRLDTVLLILFSALRNRHALADLVSGYVDTHTLRHQLLLLLPGFILGFVVVQVCRFFLGLAAGTRDAAKWTTPVRPLLIPCTTTHRRTFPEKHAFEYSYLVVGIPVGWSGTYAGMVSSDVQAPGWTSLFSVSPQPGKGWFDVDPADYLDRGNGHLGLRGKLDAYLESQGADPAQYPGAYLVTAARFMGYHFNPVSFWYLYSKDKELAAMILEVNNTFGERRMYFLTTDALPSEQRLKRGDDTGEGVSEPDSTGDQESNGKRPTVRLTKQWPKDFHVSPFNSRKGAYSLSATDFFGPGARGACVLDNTITLKSSKDHPKLVARLFNSGPAIDPGSMSAPQKLAFLCRWWWVGFLTFPRIVKEAGVLFFGRRLHVWYRPEPLKESMGRRADATESRLEPIFRAYLRHLVKQSAAAVAVRYIPAGMDSAGPEVMQSPAAKKSPKRAEELDFKVLTPAFYARFVHYAHDLEAVCCEFQDNSTIWISRPDLLPKLILKKPTPPLKTTNVVDFVCFRAIRALRRRPERIERPLTSAGSPGEGQRDGGGGVQKVDIRDFRISSMDGFILRHPEAQMRSVYRSLVLRVFLADRLALGSVELLGLQHLIVRAGVAWALSSLVAPLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QED7</accession>
    <name>E3QED7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ADP-ribosylation factor family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_04387</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093263.1">
        <property type="nucleotide sequence ID" value="XM_008095072.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QED7"/>
    <dbReference type="STRING" id="645133.E3QED7"/>
    <dbReference type="GeneID" id="24409752"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04387"/>
    <dbReference type="eggNOG" id="KOG0075">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040729_10_3_1"/>
    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098852">
        <property type="term" value="C:lytic vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04159">
        <property type="entry name" value="Arl10_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001015">
        <property type="entry name" value="ADP-ribosylation factor-like protein 8B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044154">
        <property type="entry name" value="Arl8a/8b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45732">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45732:SF7">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="27"/>
            <end position="34"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="130"/>
            <end position="133"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ29243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="183" mass="20795" checksum="F8FA4F3D9A572678" modified="2011-01-11" version="1">MAGLFRKVYDWLLRTFWATEMDVTMIGLQNAGKTSLLRVLAGGEFTIDSIPTVGFNMKRVQRGHVTLKCWDIGGQPRFRTMWERYCRGVNAIVFIVDIADVDLLQQAREELHALMGQASLREIPLLVLGNKSDLPQKLSVDELIDALDLKSIGHREVCCYGISAKEETNLDAVLQWLMKWANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QF10</accession>
    <name>E3QF10_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tyrosine phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_04592</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093468.1">
        <property type="nucleotide sequence ID" value="XM_008095277.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QF10"/>
    <dbReference type="STRING" id="645133.E3QF10"/>
    <dbReference type="GeneID" id="24409957"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04592"/>
    <dbReference type="eggNOG" id="ENOG502S0PE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057546_1_3_1"/>
    <dbReference type="OrthoDB" id="449382at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000123">
        <property type="entry name" value="Similar to protein tyrosine/serine phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026893">
        <property type="entry name" value="Tyr/Ser_Pase_IphP-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126:SF1">
        <property type="entry name" value="TYROSINE SPECIFIC PROTEIN PHOSPHATASES DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13350">
        <property type="entry name" value="Y_phosphatase3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="2">
        <location>
            <begin position="151"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ29448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="301" mass="33286" checksum="8A11A10FDE75ACE9" modified="2011-01-11" version="1">MTDANPKAGAKLPSPPFHTIPGLPNFRDAGGYPIDAQPGRILRPGVVFRSAEPSRLTDDGVTRLQDLGITHVYDLRSTIELKRLAQAGTSCNVRDWPGAQRVFVPVFRDEDYGPEAIALRYRNYSSDSTEGFTKAYTDILRTASEPDHPNDPFRTILSHLATPNPPSPMLIHCTAGKDRTGVICAIILSLCGVADEVVAHEYSLTNIGLQDRREEIVNHLLATEALKGNLQGVRRMISSPKESMLATLAKLREEYGSIEAYVQNRCRVSAEAIDKIRSNLVVDISDEHQALDWISHSKYLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>E3QF80</accession>
    <name>E3QF80_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RhoGAP domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_04662</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093538.1">
        <property type="nucleotide sequence ID" value="XM_008095347.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QF80"/>
    <dbReference type="STRING" id="645133.E3QF80"/>
    <dbReference type="GeneID" id="24410027"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04662"/>
    <dbReference type="eggNOG" id="KOG1450">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010730_3_0_1"/>
    <dbReference type="OrthoDB" id="437889at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07652">
        <property type="entry name" value="F-BAR_Rgd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000063">
        <property type="entry name" value="Rho GTPase activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031160">
        <property type="entry name" value="F_BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001060">
        <property type="entry name" value="FCH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050729">
        <property type="entry name" value="Rho-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176:SF136">
        <property type="entry name" value="RHO GTPASE ACTIVATOR (RGD1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176">
        <property type="entry name" value="RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00611">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00055">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51741">
        <property type="entry name" value="F_BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-BAR" evidence="5">
        <location>
            <begin position="68"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="4">
        <location>
            <begin position="577"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="216"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="374"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="480"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="25"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="222"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="377"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="396"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="434"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="501"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ29518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="772" mass="84737" checksum="71458A1E1E250FDA" modified="2011-01-11" version="1">MADLRSSPSEDDNLPSHNEQRDRTSSMSLGTTELTTTPPSQNGGVTTSNGDAPAAVETASAPTSEVSRQVQDVLSSDIGVATMLNQLKASIASAKEFALFLKKRSHIEESHASSLKKLSRISQETMHQPDHRQGTFAQAYSEMMYIHERMAENGSQFAQSLQTMHDDLLELAAVAERSRKGWKANGLAAEQRVADLEAAMRKSKAKYDSLAEEYDRARTGDTSRNSGKMFSLKSKSGPQHEEDLLRKAQAADQDYQSKVQTLQSEKAELIARTRPEAISALQDLVKETDSGLALQMQKFASFNEKLLLSNGLSISPIKGHGSGGSRSLREAVMAINNEKDLHDYLISHYSRVANNNGEVKYEKNPILANARHPAMGHQSNASVSNVLQNSGPPPGQGQHQQQQQREMPPPARPGGPQQPVEPLRDFAPPNMPVSQLQRPSSQHQQQPPQSQHGRSFSANNMLNQPSQQQQFQANRNSGVVTSRYNGGAMASQGPPQLGALPFQTSQSPPPQQQQQPASPPQQSQYQPPPQQQRQSNPMQQYPPQGPPPGAGGYPPHNKAPSGPPGPAPSAASPVFGLSLTRLYERDGLPVPMVVYQCIQAVDLYGLGVEGIYRQSGSLTHINKLKTMFDTDSSNPLLDFRNPENFYHDVNSVTGLLKQFLRDLPNPLLTTEHHSELIEAAKLEDDIVRRDSLHAIINSLPDPNYATLRSLTLHLHRIMENSHINRMNSHNLSVIFGPTVMGTDPSTSIADAGWQIKVVDTILQNTYEIFDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QG33</accession>
    <name>E3QG33_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL4m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_05012</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093888.1">
        <property type="nucleotide sequence ID" value="XM_008095697.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QG33"/>
    <dbReference type="STRING" id="645133.E3QG33"/>
    <dbReference type="GeneID" id="24410377"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05012"/>
    <dbReference type="eggNOG" id="KOG1624">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041575_4_0_1"/>
    <dbReference type="OrthoDB" id="275876at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1370.10:FF:000016">
        <property type="entry name" value="60S ribosomal protein L4, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_uL4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013005">
        <property type="entry name" value="Ribosomal_uL4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_uL4_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10746">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10746:SF6">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL4M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="Ribosomal protein L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="119"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ29868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="326" mass="35912" checksum="649926C91F1696AE" modified="2011-01-11" version="1">MAGKGVRSLSEAMRGLSLSSTCRAANPATSFVGSSSFTRSMATEAPFPGITTSAYATPKTTEPWAPTTSVPVTIHAFPTLEPRSLESYSTKHLYLPLRRDLLHLAVVFEGDAARQGTASTKTRWEVRGSHRKLHPQKGTGRARAGTKQSPIRRGGGVSHGPKPRDFSTRLNRKVYDVAWRTALSYRYRRGQLVVCEDGMELPLPLDFTKLADAGAVGPQIAAEYRRKWMMQVLEANEWGKAHGRTLFVTDGQRPRLWDTMEAAGDQGRCLDVNEVDVKDLLEEGRVVIERTALREMIESHQSDLVTKVFINGALKTGPAIGEPLVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QG89</accession>
    <name>E3QG89_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_04829</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the APC13 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093705.1">
        <property type="nucleotide sequence ID" value="XM_008095514.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QG89"/>
    <dbReference type="GeneID" id="24410194"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04829"/>
    <dbReference type="eggNOG" id="ENOG502S7KP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083683_3_2_1"/>
    <dbReference type="OrthoDB" id="2351920at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008401">
        <property type="entry name" value="Apc13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28526">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28526:SF1">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05839">
        <property type="entry name" value="Apc13p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ29685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="106" mass="11742" checksum="EF8B4B58B91E52AA" modified="2011-01-11" version="1">MHRARDADLFEDFCKEKLPDDEVYVPPQHQPINPEDEDDVVPDQHAAFGITKATQRQREAAWKDLGLAGLMNRGPPAAGRVGAGQGSSRRCRRRRCEEAAAMGLMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QG92</accession>
    <name>E3QG92_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_04832</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093708.1">
        <property type="nucleotide sequence ID" value="XM_008095517.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QG92"/>
    <dbReference type="GeneID" id="24410197"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04832"/>
    <dbReference type="eggNOG" id="ENOG502SG6B">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_121547_1_0_1"/>
    <dbReference type="OrthoDB" id="5214669at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ29688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="169" mass="18196" checksum="4F9939B28E70C042" modified="2011-01-11" version="1">MAVPQEKVAVHHHVTSVALPEKAAYAKLSDGVTSGNLTPIASTPEKSLEMPRDSNLSTPRSYRNENPFDTDIEAMITTTSSTDPYAMKSITTTKDCPTIWPGKQDWKAKAKAAKRDRGSCACMARMSKKNRIIMKVAIGLLIIGIGVGVGFGVSKPLGAPIWGDSEKNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QI20</accession>
    <name>E3QI20_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">HAUS augmin-like complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_05652</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Spindle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HAUS1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697349">
        <property type="protein sequence ID" value="EFQ30508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094528.1">
        <property type="nucleotide sequence ID" value="XM_008096337.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QI20"/>
    <dbReference type="GeneID" id="24411017"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05652"/>
    <dbReference type="eggNOG" id="ENOG502S1U0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068908_0_0_1"/>
    <dbReference type="OrthoDB" id="5372507at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070652">
        <property type="term" value="C:HAUS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005819">
        <property type="term" value="C:spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051225">
        <property type="term" value="P:spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026243">
        <property type="entry name" value="HAUS1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31570">
        <property type="entry name" value="HAUS AUGMIN-LIKE COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31570:SF1">
        <property type="entry name" value="HAUS AUGMIN-LIKE COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25762">
        <property type="entry name" value="HAUS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ30508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="306" mass="33724" checksum="CFDBB8CC5D1D552C" modified="2011-01-11" version="1">MAHLPPSTAIFSPSIARIAASTAKDWSYVGSWLASKYQGRPVPSFERNSETLKALLALANSNENADEERELVASAEIGAIHDLAATQDLLETNPELPASDAAREMMLGAVQDHLTREGRTALNSMATLSCQLTVAYPDAEALGRSMIGLHAEASDVEQARVRVHILQKYIDQESAAADELLRTLHSDDYKPANDLARQNLEMQRRVKAMAARMPELRDRISNLSQYTIASHPTIEQMAQKEAGYLGLLAEKKSLEEDVDQFSGLPDDVKTARAELEHLRAEVLAITRHRDAIFEGLVERESPRKGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3QI33</accession>
    <name>E3QI33_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_05665</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697349">
        <property type="protein sequence ID" value="EFQ30521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094541.1">
        <property type="nucleotide sequence ID" value="XM_008096350.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QI33"/>
    <dbReference type="GeneID" id="24411030"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05665"/>
    <dbReference type="eggNOG" id="ENOG502QT8T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037224_0_0_1"/>
    <dbReference type="OrthoDB" id="192702at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021276">
        <property type="entry name" value="DUF2855"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11017">
        <property type="entry name" value="DUF2855"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ30521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="418" mass="46124" checksum="5F49798D0E46E754" modified="2011-01-11" version="1">MVFEIHVIIKRDISMHETLTVDIPMPRLAASSIRIRTSLIGITSNNFTYATLGDMLQWWNTWPVPIDGPAPYNNRDEWGIVPAWGFARVLESTVDAIQTGGLLYGFWPTSSHPFDMRLEPAEPKGHFREISEHRQGLGSIYNHYNLVDESAQSEEFRAWFANVYPPWNGGYVLNRFTYPTDFKPVHPLGQGAGEWTDQDADLSSAMVVSLSAASRTARSFTWNLARNRKPGNGPLALLQATSVPQSLTPAFESEFEIKAVNYDSLVSQEVTGWIAGFQPKRVVVADFGGPPEVTEKLLETIKSALSESTVISNLLVGAQPKVVPQNEMIARMGSQKKWGTVQLNTTGAVDAGIAAEGAEHYHQENVSAFKRSLKENIAGDLELAWGSGVGGANGVEKAWEDLAKGTLSFNKAWVYRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QI75</accession>
    <name>E3QI75_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pirin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_05834</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="2">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pirin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094710.1">
        <property type="nucleotide sequence ID" value="XM_008096519.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QI75"/>
    <dbReference type="STRING" id="645133.E3QI75"/>
    <dbReference type="GeneID" id="24411199"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05834"/>
    <dbReference type="eggNOG" id="ENOG502QQ5A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045717_0_1_1"/>
    <dbReference type="OrthoDB" id="198735at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02247">
        <property type="entry name" value="cupin_pirin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02909">
        <property type="entry name" value="cupin_pirin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012093">
        <property type="entry name" value="Pirin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008778">
        <property type="entry name" value="Pirin_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003829">
        <property type="entry name" value="Pirin_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13903:SF8">
        <property type="entry name" value="PIRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13903">
        <property type="entry name" value="PIRIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02678">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05726">
        <property type="entry name" value="Pirin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006232">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pirin N-terminal" evidence="4">
        <location>
            <begin position="22"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Pirin C-terminal" evidence="5">
        <location>
            <begin position="177"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006232-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ30690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="304" mass="33649" checksum="4D89ACCFBCB8D727" modified="2011-01-11" version="1">MSVSRAIVQVFRAPEQAEGAGARVRRAIGSIHKRNFSPFLMFDHMSGSTGAGFPDHPHRGQETISYILKGSVEHEDFAGNKGILRAGDAQFMTAGRGIMHSEQPLPEDDGTPGAGFQLWVDLPKHLKMCEPRYRDLGAKEIPQVQLDNGQVYVKVISGRSGGVVSVKDLAYTPVWFLDVEIKPGGKFTQLLPQEWNAFAYVFEGEAVFGSKSKSQSKGKKFDAVIFEKEGDVVDAEVPDTAHGSARLLLIAGQVLDQPIAQHGPFVMNSREELQQAVEDFYTHKNGFERAKDWRSESSKRKNVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIR7</accession>
    <name>E3QIR7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05899</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094775.1">
        <property type="nucleotide sequence ID" value="XM_008096584.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIR7"/>
    <dbReference type="STRING" id="645133.E3QIR7"/>
    <dbReference type="GeneID" id="24411264"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05899"/>
    <dbReference type="eggNOG" id="ENOG502RQ3J">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012924_0_0_1"/>
    <dbReference type="OrthoDB" id="5366163at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="848"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="850"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="873"/>
            <end position="882"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="882" mass="98083" checksum="2031633222502322" modified="2011-01-11" version="1">MTAADRLECPLLLCRKRFPSHEAMLRHLYSCDQLSTGEYWCYECGKAEKFTDGKCKRCLGHPGKRRRIMSVAKNFFSSLGQKSKNQGMLDLDMKNASDIAIFPPPSYDSCIQPQQVELSSCSEILEIDSIEVPLPTPTNIDRGIMEAESAMSMAMEPTALESAVSVMPDLSFDWLLQTNVGANDNSISGKPDRPSLSLYTYGLEQRRKQHQPTTRTKNLSPSNSLRSNASTDTTASYLVSPASAFSGTWTTAETGITSPASDSSSGGLLSRGCSNASRYSNYSIQPHAFISELPADDIMLQPLPLTLSEDLDCDQQLSLLDTSILKPRRSETRTCGPGKTFDAPATMVRATDMAMPAFAVDANSLVGSAWDTLKTHITSSLEKLQHLSRNPLVEQLQGLSSQDVANKGIATLKVLLEGIRPTSSIDMLCFVHITYSLSLIVHEDDARNRSRQLFAQAFRCSDWLVGCEREQYTEVALAIWQPLDFSPSEMNVVLSERHQDAISSPSSLKGKERATSWPRKPLEKNVLLEVACFFLDELERTALPSKDLESSEVLGSMLWTKHSTHATDSLVLKESLDATCRALRSEVHRGFAHAKGLNSKIKRIQKRIGSSSVRSARRVELELLQAGKGCVTLQEYFDSYVPMVRELLDDVYNQHVPRGLSRTRYHVHGTDLMQTIISRICEKEAIKHTTQDTTNVTSEAALDEFIRSTTTALDDSWESFLTVQEDPLAMPTPLTGAQMMMMDDTTLADTVTTFCEAGELPTRPTFPMPPTRSKVDVESFDEMARASPSGAGQKFELKTSDSCEICGYQPKGDPQWFKGSMAKHKKLQHSTAPPKIYRCPYPGCTSQYKNRPDNLKQHQQDKGHFVDGETGRRPSKRKKREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIS3</accession>
    <name>E3QIS3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Chaperonin 10 kDa subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_05905</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Eukaryotic CPN10 homolog which is essential for mitochondrial protein biogenesis, together with CPN60. Binds to CPN60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the GroES chaperonin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094781.1">
        <property type="nucleotide sequence ID" value="XM_008096590.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIS3"/>
    <dbReference type="STRING" id="645133.E3QIS3"/>
    <dbReference type="GeneID" id="24411270"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05905"/>
    <dbReference type="eggNOG" id="KOG1641">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_132825_0_0_1"/>
    <dbReference type="OrthoDB" id="184876at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051131">
        <property type="term" value="P:chaperone-mediated protein complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045041">
        <property type="term" value="P:protein import into mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00320">
        <property type="entry name" value="cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.33.40:FF:000002">
        <property type="entry name" value="10 kDa chaperonin, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.33.40">
        <property type="entry name" value="GroES chaperonin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00580">
        <property type="entry name" value="CH10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020818">
        <property type="entry name" value="Chaperonin_GroES"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037124">
        <property type="entry name" value="Chaperonin_GroES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018369">
        <property type="entry name" value="Chaprnonin_Cpn10_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772">
        <property type="entry name" value="10 KDA HEAT SHOCK PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772:SF0">
        <property type="entry name" value="10 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00166">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00297">
        <property type="entry name" value="CHAPERONIN10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00883">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00681">
        <property type="entry name" value="CHAPERONINS_CPN10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00056825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ30761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="106" mass="11461" checksum="25389096F138D272" modified="2011-01-11" version="1">MATSVRSFRALVPLLDRVLVQRVKAETKTASGIFLPESSVKELNEAKVLAVGPGALDRDGKRLPMGVNSGDRVLIPQFGGSPVKVGDEEYHLFRDSEILAKINESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIW8</accession>
    <name>E3QIW8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05950</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094826.1">
        <property type="nucleotide sequence ID" value="XM_008096635.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIW8"/>
    <dbReference type="GeneID" id="24411315"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05950"/>
    <dbReference type="eggNOG" id="ENOG502T457">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2120905_0_0_1"/>
    <dbReference type="OrthoDB" id="4843494at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="62"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="114" mass="11827" checksum="858B77BE86F6A9C9" modified="2011-01-11" version="1">MRPVSIAPLLAPATALPIAPGQVNVPPEFNSKIGSPSPVIDCVGIAVCNTITVDNGNQSPGSLSQPKQTPLQQQQQQQTGSGGVGGSLRRFSAPALLFQGCWIVSALRLVTRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJ35</accession>
    <name>E3QJ35_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_06017</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094893.1">
        <property type="nucleotide sequence ID" value="XM_008096702.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJ35"/>
    <dbReference type="STRING" id="645133.E3QJ35"/>
    <dbReference type="GeneID" id="24411382"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06017"/>
    <dbReference type="eggNOG" id="ENOG502SKGQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1049769_0_0_1"/>
    <dbReference type="OrthoDB" id="3251507at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027796">
        <property type="entry name" value="OTT_1508_deam-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42037">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42037:SF1">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14441">
        <property type="entry name" value="OTT_1508_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="265" mass="29916" checksum="3A138FB653FD3388" modified="2011-01-11" version="1">MNAFQAGLPLDQRTTVRSAGVIISRMTSVAAEHEMYQRYANELQRCDLDRLIADQCRKQTFRPIAHSEVLLLEWLRTEFAEETHSIPFYNNIKYIGCSKPTCRLCEYYFAAHNSGVRVRPPHRNVYANWVVPDVLVEGDTSQYKVKMIDAVLRKIREDVFLALSEKVSERKRFDSDTYSFWPTYQSTTGVSSNLGGLASLVEGLSLASAESASYFEATRDVRIGDDAQSVVTQGNNDRDYGDDDDDGGGTLLFAGRNTRIQTLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJ50</accession>
    <name>E3QJ50_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADH:flavin oxidoreductase/NADH oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_06032</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094908.1">
        <property type="nucleotide sequence ID" value="XM_008096717.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJ50"/>
    <dbReference type="STRING" id="645133.E3QJ50"/>
    <dbReference type="GeneID" id="24411397"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06032"/>
    <dbReference type="eggNOG" id="KOG0134">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012153_0_0_1"/>
    <dbReference type="OrthoDB" id="276546at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003959">
        <property type="term" value="F:NADPH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02933">
        <property type="entry name" value="OYE_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000138">
        <property type="entry name" value="NADPH dehydrogenase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="NADH OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893:SF91">
        <property type="entry name" value="NADPH DEHYDROGENASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="2">
        <location>
            <begin position="4"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ30888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="369" mass="40727" checksum="AC047998D10C46F1" modified="2011-01-11" version="1">MSSKLFQPLKVGQAQLSHRVVMAPLTRFRFDSDHIPLDIALEYYTQRASVPGTLIIAEAVLISPAHGGFPNAPGIWNERQIAGWKKITDAVHAKGSSMFCQLIAPGRAAVVPVLEKEGGHPLLSSSAVPISPESPVPKEMTAEDIAAAVEDFPQAGKNAIAAGFDGVEIHGANGYLVDQFLQDTCNKRTDQWGGNVENRARFPVDVATALADAVGSDKVGFRISPYSNFQGMRMEDPVPQFSFLAQKLKELKLAYLHVVESRVNNWEDVEKVEGIEFILEIWDNISPIFVAGGFTPESAQKAVDEEYEKWDVAVVFGRHFLANPDLPFRIKHGLPLNNYDRQTFYTPSIPQGYIDYPFHPDFKPGQPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJD0</accession>
    <name>E3QJD0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Meiotically up-regulated gene 154 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_06112</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ30968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094988.1">
        <property type="nucleotide sequence ID" value="XM_008096797.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJD0"/>
    <dbReference type="STRING" id="645133.E3QJD0"/>
    <dbReference type="GeneID" id="24411477"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06112"/>
    <dbReference type="eggNOG" id="ENOG502SE58">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044030_1_0_1"/>
    <dbReference type="OrthoDB" id="3363151at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043007">
        <property type="term" value="P:maintenance of rDNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007096">
        <property type="term" value="P:regulation of exit from mitosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018819">
        <property type="entry name" value="Nur1/Mug154"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28293">
        <property type="entry name" value="NUCLEAR RIM PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28293:SF1">
        <property type="entry name" value="NUCLEAR RIM PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10332">
        <property type="entry name" value="DUF2418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="298"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="392"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="309"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="350"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ30968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="463" mass="51925" checksum="528CA7483FC90F95" modified="2011-01-11" version="1">MPRLVRKKPLSERLKALLNPMDFLLWLSEELETRDWNSKALGTQLGLGFNFAFLLARANCAATEVEDDVFSDGSSGNIITFVVRPLVWILGILSFVNAFYAMTRTRQYRLFQVNVEDKPHTPSAQRVKAKSDPAASSPLRLLNNLLVSETAEARAHPDRTHDVWELSVWDPLPVSLQLICLFSPGHILVYMMFLPLVPMDPRPSVTIFNCVILQLILTVQLTFVQNRYAQQIKDTAIIHKEVLHEYDTKFVRPRLHPVVRDVGTQCSPEEAKDEESFVELGTPTTVIKREFVVTPNPHVKQEEPVHTPPISSFASRLFTPTTNRRSESFTPVPSTRSIRQNLPPAPAYQSSSTSTSNATANTGSTNFGGSLGVFSHANSPLKKTASLNEMNQGFMSPRNSREMAALEQRRGGSPLKQSETRRPTGSEALDITSAPNYNPFASAKRNKVLQQQERYPSRWSGFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJP5</accession>
    <name>E3QJP5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_06227</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697353">
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="GeneID" id="24411592"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06227"/>
    <dbReference type="eggNOG" id="KOG0054">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_27_5_1"/>
    <dbReference type="OrthoDB" id="4139357at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000055">
        <property type="entry name" value="ABC multidrug transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000066">
        <property type="entry name" value="ABC multidrug transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
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    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
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        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
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    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056227">
        <property type="entry name" value="TMD0_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF345">
        <property type="entry name" value="ABC MULTIDRUG TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24357">
        <property type="entry name" value="TMD0_ABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="240"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="290"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="470"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="517"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="851"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="891"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="924"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="986"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1070"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1099"/>
            <end position="1120"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="257"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="571"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="852"/>
            <end position="1127"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="1165"/>
            <end position="1427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ31083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1427" mass="156783" checksum="EE95320F926DD4FA" modified="2011-01-11" version="1">MHLPIALFSLFAASSSILFLILLPHRIWTLRKETVKTVSGQHRSYAKQLLAVLLVAAQLTIVIETLSNPSRPLITALSVTLSFIAYVALFPLLLLEHARSTRPSDLAVIYLLASLVYDAAVLGEQASKNGIMSLTRAEFLPTAISLFVKLCLLITESRGKGKILQVSGTKSSPEQLAGVLSRTFFWWINPILARGHTDILDEDSLPLLDSKLGSRMLRRQALRAWDQRSMPETKLTLPRVLVASLLSPFLAPIVPRLFLIVFRYAQPVLISTVVRYLSTAVDEVSPESGYALIIMAVVVYVGLAISKAVYNHRLNRLQTMVRGAVVGLINRKSLDQQSSGYSDAKAVTLMSTDANGICQSARFFHETWAQVIEVIVGITMLGKEVGWLCPVPLVIIFFCSRMSRYVAKNLQSKQKGWNESTQKRLAMTSSMLSSMKGLKMLGVTAYTESIINSLRLQELDMSSRVRWMMVAYNASANALGIFTPIITFVLFVLIARINGSALDTETAFTTTALLGLVTHPANMIMSIVPQAIGSLAAFERIQLYLLQPPRHDHRQDLEEVDGGSTCMSAAVTIDNVDIQPGPKAPPILTKVSIVVKRASVIVCLGPTGSGKTTLAKAILGEIAPVRGSISVTSKRIGYCDQFPWLPSGTLKSAICGYSSYEPSWYEEVVRLCCLEEDISLLPDGHETMIGSRGLNISGGQRQRVALARAIYARCDIMIFDDAFSALDGKTESRIVWNLLGPDGLCRTMETAVLVISNSASFFHLADELVVLGDNTVKYRGTLDNLPQSPEQILKVNTDAAMNDGKNKEIHADKTLQNQELRVADAISDLSRATGDISLYSYYIKAVGFRKFLTLLACTSCYSFFVTFPQYWLQKWTEAPPSQTNFYVGGYLIASLLAWVSTNGSMWSTHILIAPRSGAELHRRLISTVTGASLGFFSTTNTGVILNRFSQDLELIDRQLPPAILALSNQVSKLIVQTTLLFSAQKFMSLTLPFCLAIVYLIQRVYLRTSRQLRLLDLEAQSAVYSSFLESDEGIITIRAFSWQNKIEDMNISSLDKSQQPAYTLLCLQQWLGLVLDLLVAAIATILIVLALMLRGSTTAGQIGMAMNLVLFANTTLLGLVTSWTNMEISLGAISRLKDLEAKTPREDKPCESYSPVDAWPSSGIVECDDISVAYKPGILALKNVTIKVSSGQKLVVCGRTGSGKSTLLLTLLRLLDTTSGRIKVDGLDISLIPRSLIRERCFITIPQDPFVFGQATLRFNLDLAASLPDEDIAAALQRAGLWSHFTYGRPNLSPTETKSILDKTMADLPGMSAGQMQLFALARALVRLQVLNPRQSPSDAALSRPHRMPVLLLDEATSSLDPETEAVMQKVLHQDFTKRGHTVIAITHRLSGVTKNMHPDQDMVAILSEGRLKMVGRAQEFIGDISI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKA8</accession>
    <name>E3QKA8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_06440</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697354">
        <property type="protein sequence ID" value="EFQ31296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095316.1">
        <property type="nucleotide sequence ID" value="XM_008097125.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKA8"/>
    <dbReference type="STRING" id="645133.E3QKA8"/>
    <dbReference type="GeneID" id="24411805"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06440"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_1_1"/>
    <dbReference type="OrthoDB" id="1888931at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050085">
        <property type="term" value="F:mannitol 2-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050664">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019594">
        <property type="term" value="P:mannitol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000090">
        <property type="entry name" value="NADP-dependent mannitol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF1">
        <property type="entry name" value="NADP-DEPENDENT MANNITOL DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ31296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="276" mass="29910" checksum="C56FFEA659BD59DE" modified="2011-01-11" version="1">MSMSTEDCQKPREGFPRPFPHTPSNVLEQLRVTGKVTVVTGAADGIGFAVSEAMAEAGGNVALWYNSNDVAIQKARDLASTHNIKTLAYKVDVSDPTQVQETIAKVVRDFGKIDVFVANAGMAISKPILEQTLDEYRKQMSVNVDGIVYCAKYAGEVFERQGSGNLIITSSMSAHIVNVPVDQPVYNATKAFVTHFGKSLAREWRGFARVNVVSPGFFDTKMGAGPQALQEAYRMAALGRQGHTKEIKGLYLYLASDASTYMTGSDVIIDGGYVLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKJ0</accession>
    <name>E3QKJ0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_06522</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697355">
        <property type="protein sequence ID" value="EFQ31378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095398.1">
        <property type="nucleotide sequence ID" value="XM_008097207.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKJ0"/>
    <dbReference type="GeneID" id="24411887"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06522"/>
    <dbReference type="eggNOG" id="ENOG502R2QQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083929_0_0_1"/>
    <dbReference type="OrthoDB" id="6105938at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="50"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ31378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="240" mass="26554" checksum="68A27E316951E0E1" modified="2011-01-11" version="1">MSPVADYELLNRASGRSKALTDDESRAQAQAQELYHARKILDDMVQESTCNICYEPLCSMHVTHCGHSHCTQCIRTQFREMGVLNAMCGKIYAQCPTCRVEISLDVSRNGLLIVPVAIAAENQLVRLRKWSQRRAQDEKLLAQDVSLPSTASSRGRLAEAMTREDEMRTSTTGANTVAYGNGILVRDLEIPPIPYGWVQNAARSMPTIGMTSSSTETQLQLAGYQPGYIPVVYHHPPPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKP9</accession>
    <name>E3QKP9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ethanolamine-phosphate cytidylyltransferase</fullName>
            <ecNumber evidence="10">2.7.7.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">CTP:phosphoethanolamine cytidylyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_06581</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from ethanolamine: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytidylyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.14" evidence="10"/>
    <dbReference type="EMBL" id="GG697355">
        <property type="protein sequence ID" value="EFQ31437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095457.1">
        <property type="nucleotide sequence ID" value="XM_008097266.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKP9"/>
    <dbReference type="STRING" id="645133.E3QKP9"/>
    <dbReference type="GeneID" id="24411946"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06581"/>
    <dbReference type="eggNOG" id="KOG2803">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031246_0_0_1"/>
    <dbReference type="OrthoDB" id="40021at2759"/>
    <dbReference type="UniPathway" id="UPA00558">
        <property type="reaction ID" value="UER00742"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004306">
        <property type="term" value="F:ethanolamine-phosphate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd02174">
        <property type="entry name" value="CCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02173">
        <property type="entry name" value="ECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041723">
        <property type="entry name" value="CCT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044608">
        <property type="entry name" value="Ect1/PCYT2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45780">
        <property type="entry name" value="ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45780:SF2">
        <property type="entry name" value="ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5 14" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cytidyltransferase-like" evidence="13">
        <location>
            <begin position="24"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="412"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ31437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="448" mass="50471" checksum="DC9B25EDA9413F29" modified="2011-01-11" version="1">MVNSDPEHPPGEPAPEILEERIWIDGCFDFFHHGHAGAIVQARQLGSELYIGVHSDESILENKGPTVMNLQERLAAVDACRWVTKSIGRAPYVTQLEWISHYGCKYVVHGDDITSDAEGYDCYRFVKEAGRFKVVKRTPSISTTDLVGRMLLCTKTHFIKSLERQLAGEEGEGTSKAEIKANADAMTERMKLYATDETGKNPGVEVWFWSASDEAKAEAANEEKGDFRRFLPGKGPKLGQRVVYVDGGFDLFSSGHIEFLRRVVEAEEEQARKEGWYSEQAVNERVGKGGDYPPAYVVAGIHSDEEINHWKGINYPIMNIYERGLCVLQCRYVDAVVFGAPFSPTRAYLTALPWGTPDAVYHGPTSFMPLTYDPYTAPKEMGIMREVGEHEFASVNAGTIVQRIMKSRDMYEERQRKKGIKAEGETAARDRELLEEEQARREAERARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKV1</accession>
    <name>E3QKV1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Dynactin subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_06633</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the dynactin subunits 5/6 family. Dynactin subunit 5 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697355">
        <property type="protein sequence ID" value="EFQ31489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095509.1">
        <property type="nucleotide sequence ID" value="XM_008097318.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKV1"/>
    <dbReference type="STRING" id="645133.E3QKV1"/>
    <dbReference type="GeneID" id="24411998"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06633"/>
    <dbReference type="eggNOG" id="KOG3121">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_088622_0_0_1"/>
    <dbReference type="OrthoDB" id="417208at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005869">
        <property type="term" value="C:dynactin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03359">
        <property type="entry name" value="LbH_Dynactin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047125">
        <property type="entry name" value="DCTN5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46126">
        <property type="entry name" value="DYNACTIN SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46126:SF1">
        <property type="entry name" value="DYNACTIN SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21711">
        <property type="entry name" value="DCTN5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00034706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ31489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="195" mass="20874" checksum="1AF3253E1A7D94F8" modified="2011-01-11" version="1">MSRRPAKGDYIETDTGNKVARKATLVGTQNIMLGGKTVIQPEVMIRGDLSRTAQPSAAGAPANSTAVAIGRYCFLSRGAVLRPPGRMYKGVFTYMPLRMGDHVFVGQNTVIQAASLGSHIHIGRDCVIGEFAIVKDYVRVLEGTVVPPNMVIPSFSVVAGQPARVVGEVPEGGHEAFELRELYKTVGNNPQPLTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKX3</accession>
    <name>E3QKX3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_06655</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697355">
        <property type="protein sequence ID" value="EFQ31511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095531.1">
        <property type="nucleotide sequence ID" value="XM_008097340.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKX3"/>
    <dbReference type="STRING" id="645133.E3QKX3"/>
    <dbReference type="GeneID" id="24412020"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06655"/>
    <dbReference type="eggNOG" id="ENOG502RYFN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047435_0_0_1"/>
    <dbReference type="OrthoDB" id="9971601at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36142">
        <property type="entry name" value="METALLO-HYDROLASE/OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36142:SF2">
        <property type="entry name" value="METALLO-HYDROLASE_OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ31511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="322" mass="35691" checksum="6C711F24126CAC96" modified="2011-01-11" version="1">MDRAKLIDTLASAQSSPKRPILTLMNGDTTWLVSVPRPAGTKGKAFYHILVDPWLEGHAEVGFGWVVRLQLKEKAALDSIEAIEDWIREIETVCGTTDGEHEQWLDAVLVTHANLDHLHKPTLRTLSKSAQVLAVQEAATMISSMDHFENIIAVPDFVPGEEWPATPDMPGSLSIFRLQSKGDKYTNLCHAVIIGIPTEDGKSEAILYTPHGVEPEAVEAVRKANSDASFLAMLHPLNKAGTMGFISRGVAEGLRIERENSVRHWVNTHDDNISFSGVLSYIMRYGRATLEQGLKQEAREKVEEQRRPDYIVVENGGSHILT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QL20</accession>
    <name>E3QL20_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminotransferase class-V</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_06847</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697356">
        <property type="protein sequence ID" value="EFQ31558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095578.1">
        <property type="nucleotide sequence ID" value="XM_008097387.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QL20"/>
    <dbReference type="STRING" id="645133.E3QL20"/>
    <dbReference type="GeneID" id="24412212"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06847"/>
    <dbReference type="eggNOG" id="KOG2142">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010913_4_0_1"/>
    <dbReference type="OrthoDB" id="10264306at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237:SF19">
        <property type="entry name" value="MITOCHONDRIAL AMIDOXIME REDUCING COMPONENT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237">
        <property type="entry name" value="MOLYBDOPTERIN COFACTOR SULFURASE MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="1">
        <location>
            <begin position="34"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="493" mass="54276" checksum="206FE7DF16C6A26F" modified="2011-01-11" version="1">MENIFINYPEYKSTSHLDNLRATDYSYLDKQGHIYLDFTGAGLAAHSQLRAHEGRLEKTLFGNPHSVNPTSQSATNLVEDTRARVLAYLNASPDEYTVIFTPNATGAARLVAEAYPFKRRTRLVLTSDNHNSVNGLREFARGNHAQTIYIPARAPDLRVEPSDLMSALKRRRGLFGSPHPRRSGLFAYPAQSNFSGVRHPLSWVGVAQQQGYDVLLDAAAYLPTAKLDLSAAAGVQPEFVIVSWYKLFGYPTGVGCLIVRRDALARLARTRPWFSGGTVTAASVGAHWHVMAPDEAAFEDGTVNFLSIPDVHYGLDWLDGIGMPLIATRVQCLTGWCLERLRALEHSDGSPVARIYGPTNMISRGGTICFNFLDVGGRVVDERLVAAESSAQKISLRTGCFCNPGAGEAAFGLEKRLLEKRLLEKRLLEPLNKVHSSSSLDDYVRLLAPVGAVRVSFGFVSTTEDVDRFIAFAEETYRDRLTPANGLPVHNHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLV4</accession>
    <name>E3QLV4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_06986</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095862.1">
        <property type="nucleotide sequence ID" value="XM_008097671.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLV4"/>
    <dbReference type="STRING" id="645133.E3QLV4"/>
    <dbReference type="GeneID" id="24412351"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06986"/>
    <dbReference type="HOGENOM" id="CLU_1806029_0_0_1"/>
    <dbReference type="OrthoDB" id="9972196at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ31842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="143" mass="15484" checksum="FEF880874F2ABF6D" modified="2011-01-11" version="1">MSSKPVASTLLYAASYAGAVTSLDLQAQEAGTTLEAFDSTTACAPNPSWLTLYQARSLLCCADRDLTNLTTTIYSFRDNNKGSFIPLNSRSIINRAVSSVLDLRPFFLVLAELCNIVAAYEVNPTATNVELRRSVLGWDPRAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLX8</accession>
    <name>E3QLX8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Translin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_07010</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the translin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095886.1">
        <property type="nucleotide sequence ID" value="XM_008097695.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLX8"/>
    <dbReference type="STRING" id="645133.E3QLX8"/>
    <dbReference type="GeneID" id="24412375"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07010"/>
    <dbReference type="eggNOG" id="KOG3066">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067225_2_1_1"/>
    <dbReference type="OrthoDB" id="31005at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14820">
        <property type="entry name" value="TRAX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.190">
        <property type="entry name" value="Translin, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.200">
        <property type="entry name" value="Translin, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016069">
        <property type="entry name" value="Translin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002848">
        <property type="entry name" value="Translin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016068">
        <property type="entry name" value="Translin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036081">
        <property type="entry name" value="Translin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10741">
        <property type="entry name" value="TRANSLIN AND TRANSLIN ASSOCIATED PROTEIN X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01997">
        <property type="entry name" value="Translin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74784">
        <property type="entry name" value="Translin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ31866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="255" mass="29291" checksum="8999856697B21173" modified="2011-01-11" version="1">MSKRDRDGNTRTHEPKQKPAVPESQFTPMFMNFRNELDQHHDRRERIIKASRDVTALSKKIIFTCQRVNKLGDLPNFANKEIATRMEEIKNHLTAIEGDIQGINRYRYAYSLRCLEELVEALSFVHYLRTQTLITPEETAAAVPANVSITENDYMYGLFDLFGEMMRFATVTTAQTGQLAGVEGRNILVDIHELSSCFEILPEIPTKDFRGKMEVMRQSVRKVEKLGYGLAIRGTERPKGWVPDMKEDFDPSSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QM85</accession>
    <name>E3QM85_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transaldolase</fullName>
            <ecNumber evidence="2">2.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_07117</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + beta-D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:17053"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.2" evidence="2"/>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095993.1">
        <property type="nucleotide sequence ID" value="XM_008097802.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QM85"/>
    <dbReference type="STRING" id="645133.E3QM85"/>
    <dbReference type="GeneID" id="24412482"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07117"/>
    <dbReference type="eggNOG" id="KOG2772">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047470_1_0_1"/>
    <dbReference type="OrthoDB" id="1711136at2759"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00414"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004801">
        <property type="term" value="F:transaldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009052">
        <property type="term" value="P:pentose-phosphate shunt, non-oxidative branch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001585">
        <property type="entry name" value="TAL/FSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018225">
        <property type="entry name" value="Transaldolase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683">
        <property type="entry name" value="TRANSALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683:SF34">
        <property type="entry name" value="TRANSALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00923">
        <property type="entry name" value="TAL_FSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00958">
        <property type="entry name" value="TRANSALDOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0570">Pentose shunt</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0704">Schiff base</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ31973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="338" mass="37983" checksum="4E6D3D22A1D24B13" modified="2011-01-11" version="1">MASQDGSLLETLRSTSQVDCDTLDVDVAADLGPFRDHTSNQAIAYNELTKVTPDGKLHHEKLIRDSVKDAYGWAQATWPDIDPIVLAVEIMMVRLSLQFVPYLTGYFHIQTNTKWSYSVEKTCKNAERIVETFKKLEPNFDTSRVCIKIPASWEGIAACRILEKKGIHTLATTMFCMEQAVLAADAGCTYIAPYVNELKVHFVPGYVDEHKAFDFCRQAQLYYAETKAKTQVLAASLTSIAEVMQLAGIQHVTVSPPLLRGLAAQPASTWTEQVGEYFAAGPDKPWTRNFETELRDESEWRIAFTRSDSGKSEEKLIQAINIFSDKQDALEELARRFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMD3</accession>
    <name>E3QMD3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_07165</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096041.1">
        <property type="nucleotide sequence ID" value="XM_008097850.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMD3"/>
    <dbReference type="STRING" id="645133.E3QMD3"/>
    <dbReference type="GeneID" id="24412530"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07165"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_13_0_1"/>
    <dbReference type="OrthoDB" id="2585655at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF20">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G13880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="134"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="219"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="312"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="396"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="423"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="461"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="488"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="66"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ32021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="530" mass="56754" checksum="A1201215C6CC8F4E" modified="2011-01-11" version="1">MGWGVVETPGQPFAPGTVLLEDKKIPDEITVGDDGLKRKQGVILQPQPGDDPNDPLMWSTAWKFAHLFVIVFGSSAANAITTMVVPGIAPLVDKFGATQGSISSLILNAPTFFTSLAAFFVVSGAEIFGRRPFYVISTAVMAAANLGSFLATTYSVLVVSRAIAGIFSAATFTLVTATIADIFYVHQRGSAVASWNVGLTVGGQLGQIIGGVVTDKLGISAVFGLAAVVFAALFFPTYFLVLESAYFKRGDDIGSRQQEKKSKDSVEVEYAKNLPARKVPYLKQLGLFRGKMTDKTFWMGSLKPLFFLSSPIILYSALLNSLVLVLSAGVTNLIVIILSDAPYNLQPTDIGLTGLPILVVSLIGGPLIGWLSDWSVRFMARSNGSNPGVAEPEFRLVLLIIALPMTAAGLVGLGIAIQQGQPLLWLLTWLSLISFGSCIGVQVSVGYMIDYLPSHSAQAFTIVNMIASLVVFAGTTPLIDWLQASGPVVVFSSLAGVTMANLIFSFPLYVYGKRIRTWYGSTRLSRWVLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMG6</accession>
    <name>E3QMG6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Argonaute siRNA chaperone complex subunit Arb1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07198</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096074.1">
        <property type="nucleotide sequence ID" value="XM_008097883.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMG6"/>
    <dbReference type="STRING" id="645133.E3QMG6"/>
    <dbReference type="GeneID" id="24412563"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07198"/>
    <dbReference type="eggNOG" id="ENOG502S0TP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023193_2_0_1"/>
    <dbReference type="OrthoDB" id="435402at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033167">
        <property type="term" value="C:ARC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031047">
        <property type="term" value="P:regulatory ncRNA-mediated gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018606">
        <property type="entry name" value="Arb1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09692">
        <property type="entry name" value="Arb1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="365"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="376"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="396" mass="44246" checksum="3CDE49C1C5691BC5" modified="2011-01-11" version="1">MTPAEAQEERENIYHPDLPFVERIEACIQRYRARRRLGASDQIFNKYLFLGGIDSTPRMFSGHVDADFQDMSPEEKRAATAVDTVHVSGGGSRFYNDSERAGWDVDFAGVAAGFLSENLPTMTAWDYPQMGKAVGVLENFLTYVLQHDVCPEYDANVKEALAVCQRAKVELPQTHQALLFFPGEFNLALSELFCEDYYFFGEGEFQRPANFAPENVFKVALSTVGSQKQYEAVMEGLASKSVKVVSEEECSMEVVSVHRPSTESRNLVRSVALDQGGPFAPIGWIVAKPCLIEDGFDRGEHFELSEKEETFFLDDAILSRLEPGFKLQLCVCELNIGIRFIKQARLVLVEWHTFLPQNLMLHFKEPVPNDRPPQSAAAPEAEGGPAKAAKRVSAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMJ3</accession>
    <name>E3QMJ3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_07225</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="2"/>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096101.1">
        <property type="nucleotide sequence ID" value="XM_008097910.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMJ3"/>
    <dbReference type="STRING" id="645133.E3QMJ3"/>
    <dbReference type="GeneID" id="24412590"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07225"/>
    <dbReference type="eggNOG" id="KOG0800">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021597_1_1_1"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16454">
        <property type="entry name" value="RING-H2_PA-TM-RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000127">
        <property type="entry name" value="E3 ubiquitin-protein ligase RNF181"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051834">
        <property type="entry name" value="RING_finger_E3_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45931:SF3">
        <property type="entry name" value="RING ZINC FINGER-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45931">
        <property type="entry name" value="SI:CH211-59O9.10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="10">
        <location>
            <begin position="314"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="51"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="193"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="358"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="108"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="221"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="362"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="380"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="467"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ32081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="563" mass="61356" checksum="8F42925EF16D5A15" modified="2011-01-11" version="1">MESHNTRGGHLDATAGREVVFCHACSHEWWEDEHGLQCPRCESEITEIVSPENDPREIEDGPPLHGSPGHIGRYDNDSDPEEADIEEHLHRGPGGFVVHRTIWDNSHRPGQSPNPNTRQPADANDGDQIIRRFIDMVNDFGMGTPPRPPPEETRPPGIGGILFGGQGNVRTYHRAGPGGTTSFTIATGPIHFHQGGGHSPVGPGSDPFQSIFSSVLAGAGPPQGEGMPGPGQGQRAPGGAPTLLHEILNMLNPANASHGDAVYTQEALDRIISQLMEQNPQNNSAPPATEDALSKLQRKKVDKEMLGTDGKTECTICIDDFNEGDEATVLPCKHWFHDQCVVMWLKEHNTCPICRTPIEEPSNSSGGNRNNANSNASGSHNDPNANASQRAHTAASGSSDSSHHPFDWGDAPPGIPGHWGAAAYPPRPSFFQQAPPVPEDSTRPQRSPITEWGVPFPIYGGSSTNRQDPHSTDLPSRPHEDARSSSFRSRRDSHSPSSLRRRQSDSFRTRQRSPSSGNWDRDRDNNQDAGSNHGPLNWLRNQFFRGPGSGDNSSNNTRERRRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMN2</accession>
    <name>E3QMN2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_07264</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096140.1">
        <property type="nucleotide sequence ID" value="XM_008097949.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMN2"/>
    <dbReference type="GeneID" id="24412629"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07264"/>
    <dbReference type="eggNOG" id="ENOG502QXCY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013364_3_3_1"/>
    <dbReference type="OrthoDB" id="425534at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013595">
        <property type="entry name" value="Pept_S33_TAP-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051601">
        <property type="entry name" value="Serine_prot/Carboxylest_S33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248">
        <property type="entry name" value="2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248:SF30">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08386">
        <property type="entry name" value="Abhydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179865" description="AB hydrolase-1 domain-containing protein" evidence="3">
        <location>
            <begin position="24"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="4">
        <location>
            <begin position="96"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S33 tripeptidyl aminopeptidase-like C-terminal" evidence="5">
        <location>
            <begin position="410"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ32120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="508" mass="54537" checksum="3ED8EC9CF8D12860" modified="2011-01-11" version="1">MVQPPHPRLTVGLAAAFLVTVTAVKVPQPIGPAHRDIIEWAACPGDIQPFKGSNFTSALQCSNFSVPLSHNDPSGPQVQLGIVKLPAQGERIGNLFVNPGGPGGAASSMVLRMASQKIYISDAVRQKFDIIGMDPRGVGLSTPQKCDMNLVDPPREFDATTPEGFQQLFDYNKAVGESCRTMTGPVFDNMDTISVAKDMESVRVAMGNEPMNYFGISYGTQLGAQYAALFPTAIRAMALDGMLQHTGAYASNIMTQATSLDATIQDFFRFCESSATNCGDGGQDIRKTWSKALEVAAAGNLKAVECDGTAKTGCLSTATPNNVIGAARSTLQFAEKRKNFALELKNAASGNGSYFVPGLLSGDVYTDSRSLSITTVQCQDGHFFAAKDHIEVQQVAEMTRTFTTTPGMGEFWRRVVDCTGYPVNITNPRTALSVKGTQNPVLMVHSRFDPATSLVYAVGMVEEFQNATLLLREGSGHTSYLLRGDASRAVDDYLVDLRVPPRGTVVQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMW4</accession>
    <name>E3QMW4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Scaffold protein Nfu/NifU N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_07346</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NifU family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697360">
        <property type="protein sequence ID" value="EFQ32202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096222.1">
        <property type="nucleotide sequence ID" value="XM_008098031.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMW4"/>
    <dbReference type="STRING" id="645133.E3QMW4"/>
    <dbReference type="GeneID" id="24412711"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07346"/>
    <dbReference type="eggNOG" id="KOG2358">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060555_0_0_1"/>
    <dbReference type="OrthoDB" id="565552at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.130:FF:000001">
        <property type="entry name" value="NFU1 iron-sulfur cluster scaffold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.70:FF:000001">
        <property type="entry name" value="NifU-like protein 4, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="entry name" value="Fe-S cluster assembly (FSCA)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.70">
        <property type="entry name" value="Scaffold protein Nfu/NifU, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014824">
        <property type="entry name" value="Nfu/NifU_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036498">
        <property type="entry name" value="Nfu/NifU_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001075">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11178">
        <property type="entry name" value="IRON-SULFUR CLUSTER SCAFFOLD PROTEIN NFU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11178:SF1">
        <property type="entry name" value="NFU1 IRON-SULFUR CLUSTER SCAFFOLD HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08712">
        <property type="entry name" value="Nfu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01106">
        <property type="entry name" value="NifU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00932">
        <property type="entry name" value="Nfu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="Fe-S cluster assembly (FSCA) domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110836">
        <property type="entry name" value="Hypothetical protein SAV1430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Scaffold protein Nfu/NifU N-terminal" evidence="3">
        <location>
            <begin position="82"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ32202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="316" mass="34778" checksum="B3065435B8FB2146" modified="2011-01-11" version="1">MSSYRATRTALRAVARTSRPATRPVTAPLQQSRTFASVQPAAGLLQQSHLPRRITREHPQQQAGARRSPFAGREGGIRTIFIQTEQTPNADAIKFLPNHRILPENISTPFIEYLNPRSTIAPPYPSPLAAQLMNIDGVTSVFYGADFITVSKAADANWAHIRPEVFALITEAITSGQSIVNVAEKKEGGVAGEEQQQHGEEDSLAYDENDSEVVGMIKELLETRIRPAIQEDGGDIEFRGFTDDGIVLLKLRGACRTCDSSTVTLKNGIEGMLMHYIEEVKGVQQILDQEEEIALQEFAKFEEKLKAQKGHEATAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3QN20</accession>
    <name>E3QN20_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Mitochondrial phosphate carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_07402</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697361">
        <property type="protein sequence ID" value="EFQ32258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096278.1">
        <property type="nucleotide sequence ID" value="XM_008098087.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QN20"/>
    <dbReference type="STRING" id="645133.E3QN20"/>
    <dbReference type="GeneID" id="24412767"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07402"/>
    <dbReference type="eggNOG" id="KOG0767">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039456_1_0_1"/>
    <dbReference type="OrthoDB" id="427452at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990547">
        <property type="term" value="P:mitochondrial phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044677">
        <property type="entry name" value="SLC25A3/Pic2/Mir1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45671:SF15">
        <property type="entry name" value="MIR1-PHOSPHATE TRANSPORTER OF THE MITOCHONDRIAL CARRIER (MCF) FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45671">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25 (MITOCHONDRIAL CARRIER PHOSPHATE CARRIER), MEMBER 3, LIKE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="17"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="116"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ32258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="318" mass="33377" checksum="EE310EDC9E566C07" modified="2011-01-11" version="1">MAAVKPTQSELPTFSPIDYAKFFGAGALAATSTHGAATPIDVVKTRIQVDDAMKGLNMVKAGRTIVAKEGASALLTGFGPTAVGYLVQGGGKFAGYEFFKKQFITVAGGPERAVDRRTAIYLGASATAEFFADILLCPLEATRIRLVSQRGYASGLAPGFARLAREEGIKGFYSGFVPLLFKQVPYAVGQFSVHEAAVEFIYRTMGPERKAAMTQLQSTGVELASGIVAGVAAAVLSHPADTLLSAINKGAGDPKQGATSRMIQLAREFGPKRLLLTGLGPRIVMTCGLVAGQFVIYAQCKTLVGAPAGIEIHKEESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QN27</accession>
    <name>E3QN27_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_07409</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the major facilitator superfamily. CAR1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697361">
        <property type="protein sequence ID" value="EFQ32265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096285.1">
        <property type="nucleotide sequence ID" value="XM_008098094.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QN27"/>
    <dbReference type="STRING" id="645133.E3QN27"/>
    <dbReference type="GeneID" id="24412774"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07409"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_1_0_1"/>
    <dbReference type="OrthoDB" id="6770063at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000509">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF163">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="276"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="319"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="361"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="387"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="419"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="451"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="50"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ32265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="490" mass="52905" checksum="CFAC2743186AEC51" modified="2011-01-11" version="1">MTMATVAEDQPLLVEDPLCEQDLSKHLLDFDPNGDPENPREWPTPFKWTIVGLLALTAFTVTFTCISVVPVAAHIIADLDQNEGGINSPAAALLVTIWELGEAAGPLLIAPLSEIYGRYPVMNAANILFITATVLAALSTSTPLLIAARCLTGLAVASNVLSPAIIGDIFAPDRRGSAMSLVMVAPLLGGAVGPMISGAIAQTLGWRQVLWMSAALAALCELLFLTCFRETYKMTILRRRAARHADEHGPSLHPAGVDDHRGLLKLWESVKRPFQVLFQSGVLMGLSFFGCITFAYFYVMSVSLPIILQDVYGFSPALTGLSFMAFSIGSFISVLVSNFSLDRIYVVLRGNDAVGRPEYRLPLAIIGAFTLPLSLIAYGWIAELHLPVGYLLLSVAMLGFTMLMASLPISSYVVDATGLYSASAMTGVIVTRCLAGTFLPLTSGPMMERFGYGWGFTMLGVLSICLAPIPALIMRYGHVWRQKSEYTRDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QN51</accession>
    <name>E3QN51_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_07433</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697361">
        <property type="protein sequence ID" value="EFQ32289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096309.1">
        <property type="nucleotide sequence ID" value="XM_008098118.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QN51"/>
    <dbReference type="STRING" id="645133.E3QN51"/>
    <dbReference type="GeneID" id="24412798"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07433"/>
    <dbReference type="eggNOG" id="KOG0158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_11_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11058">
        <property type="entry name" value="CYP60B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF210">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ASQL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="447"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ32289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="506" mass="58243" checksum="60BDD78E848D005D" modified="2011-01-11" version="1">MLSLELLSTSLSLRDYAALATVGIIAYSLVRTIYLLWFHPLARFPGPKFAAVSNVWYGYQWLSGRYPWAMQRAFEEYGDVVRIAPNELVFITPKAYTDIYTSSINGRPAFVKSDMLDTGDKYEGLASERDIDKHRAARKQLAPAFSPRSLKQYEPTIHAHVDEFVAELQNSPAVDEGVDIAPWFERATCDLGGSITLGHNFKNIQSGQNHPILESLLRIGHWATFRNVMRRFPLLYPLSYVFLPPKVALSYFRAHSTSKKLIRTRVQERHDRKELDYMAQFLKNETAIPPDGFLVSQAGHLILDHYESSSVLTAGICFLTTNPEIMNKLQTELRTTFKSYEDISEDKLQDLPWLNATIEEVIRLHTNVPYGLPRISPGHTVDGNFVAKGVVVSSCAYATTHSEKYFGKPYEFKPQRWLPKDHSEYDHVFDEDDRSAFRPFSAGSRNCLGQAMAYLVLRIIFAKLCWRFQWELVNKNEMDWDRDLRLYIVWQKPKVHVRLTPFEKTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QN86</accession>
    <name>E3QN86_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ER membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_07468</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697361">
        <property type="protein sequence ID" value="EFQ32324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096344.1">
        <property type="nucleotide sequence ID" value="XM_008098153.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QN86"/>
    <dbReference type="STRING" id="645133.E3QN86"/>
    <dbReference type="GeneID" id="24412833"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07468"/>
    <dbReference type="eggNOG" id="ENOG502QRTT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027878_1_0_1"/>
    <dbReference type="OrthoDB" id="5577218at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032541">
        <property type="term" value="C:cortical endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097038">
        <property type="term" value="C:perinuclear endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048309">
        <property type="term" value="P:endoplasmic reticulum inheritance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000921">
        <property type="term" value="P:septin ring assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013635">
        <property type="entry name" value="Ice2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31726">
        <property type="entry name" value="PROTEIN ICE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31726:SF2">
        <property type="entry name" value="PROTEIN ICE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08426">
        <property type="entry name" value="ICE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179873" description="ER membrane protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="236"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="301"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="353"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ32324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="436" mass="47984" checksum="EE4A8FFA243451A4" modified="2011-01-11" version="1">MWWFLRIVASAIFLLSIVLSIPVAFDVGGRDSGLAYSLALCVFYFVYSAIAVVTPAESRVRWAISVILRLSQWVVIPGLLIWALGRFAVDAGATNWVERTLQGLTSSKSTSWGEWMFGEGGVVETITLGGWDKTLRYSSPVFQLLEGFCTLLVIQAAGQITKWLVNRGRSDTWIIILLVISGSVLASAVYFLWRVAHFPYINNSDAILIGITMTSAFFLCAYGIGSGRGNPVESSLLFAYVVLCVYQIFTDYLPSESTEADQHQSSQPDFPPLPPIIMASYSTLLHMLGSLPHAVHSSLSLLYAAFQTITPSVIISLAFRLLVFYCATRIIPAVRESGARALMDEPSLEESDAANWLIGVITYFSPSILIAMYTSLLLQHFSTNDGPDGWTLRGGDPGGNVWRWTNVAATMSLYAVELYLGNEDHDGGLTNHWKMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QP59</accession>
    <name>E3QP59_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">GMC oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_07661</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697363">
        <property type="protein sequence ID" value="EFQ32647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096667.1">
        <property type="nucleotide sequence ID" value="XM_008098476.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QP59"/>
    <dbReference type="STRING" id="645133.E3QP59"/>
    <dbReference type="GeneID" id="24413026"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07661"/>
    <dbReference type="eggNOG" id="KOG1238">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002865_6_2_1"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF210">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="4">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="5">
        <location>
            <begin position="280"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ32647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="598" mass="65171" checksum="D9EF67E8AA66C6A1" modified="2011-01-11" version="1">MLLSIASVMAESYDYIIVGGGTAGLTVAARLTEDPQVTVLVLEAGADRSEDLNVLAPGLFLAMYGNPDYDWDYKTVPQTAANNKVVAHIRGKQLGGSSAMNFMFWTHPSRRDVDNWGDLGNIAWSWDALAPYFRKSEAFVAPSAQQKSDLSLNYVDPVVHGTSGPIVNEFPKLYSPFLEAWPRTMEKLGLGVKGDPRDGKALGGYVNLLNIKNATRSYAANAYLGPARQRANLKVMTESHVSRILFRNDENGIEATGVMWTQGADEVEAIAAKEVILAAGSIASPQLLELSGIGTREILEKHGIEVLVDNPNVGENLQDHVYVPLGFAVKTGLPTNEDYSNATYFQEQLDLYLQTKTGRLSSAGASSALLSLEQIAPTLNFDPPILKSNIPGLAEQYRLVFRDLKSEAIAQELTIEGGISPQFSSDTTKLFNAGSPGNFLSVLGVLEHPLSRGSVHIQSADVTAHPEIDPRYLSNPLDVQLLKTIALHLQTVARTKPLSDLLQGDGTVFQPGYHELTTQNVEDWVRNSMQSEYHPCGTCAMSPREKGGVVDEKFKVYGVKNLRVVDASVFPLIPRANIQSMVYAVAERAADFIKQDAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPD0</accession>
    <name>E3QPD0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_07862</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697364">
        <property type="protein sequence ID" value="EFQ32718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096738.1">
        <property type="nucleotide sequence ID" value="XM_008098547.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPD0"/>
    <dbReference type="GeneID" id="24413227"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07862"/>
    <dbReference type="eggNOG" id="ENOG502S6NX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_136890_0_0_1"/>
    <dbReference type="OrthoDB" id="3141857at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039965">
        <property type="entry name" value="C3H7.08c"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40466">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40466:SF1">
        <property type="entry name" value="FUNGAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ32718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="130" mass="14145" checksum="E786F361C2689680" modified="2011-01-11" version="1">MASFVTRRAFSTTVRRLAQVDAQSKQQLTQESKRNPELIILGGVMVAALGGAGLYFGRSPTSATSESPVLKAGMPWETEGEGKYKYHPGGNPKNEPKDAPSAVNTVIIPDVTLPKELHDKYNKWGKEGYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPK3</accession>
    <name>E3QPK3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_08052</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697365">
        <property type="protein sequence ID" value="EFQ32908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096928.1">
        <property type="nucleotide sequence ID" value="XM_008098737.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPK3"/>
    <dbReference type="STRING" id="645133.E3QPK3"/>
    <dbReference type="GeneID" id="24413417"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08052"/>
    <dbReference type="eggNOG" id="ENOG502SMKX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033726_0_1_1"/>
    <dbReference type="OrthoDB" id="2245989at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021833">
        <property type="entry name" value="DUF3425"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38116:SF1">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38116">
        <property type="entry name" value="CHROMOSOME 7, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11905">
        <property type="entry name" value="DUF3425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ32908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="276" mass="31445" checksum="EB5ABB2836303500" modified="2011-01-11" version="1">MSQLGELIRREDDWTGTKDAAARRRAQTRLNTRAYRKRKALEKKAHASSSTTKTLIEPEAAVECWDVEKQSASIVPASRMKQLYNARSPLLKKPRKKASWGTFFPLCPDHLITLLQYNVLRALAVNRTLISGTLVTPLDCNEEVIHVITYPSQPKVLPPTLLPTAVQQTVPHGDWSDMFPCPKARDNLIRAADTFDEDELWADCIGGLFEGFPDDEVERRGMIAWSPPWDITGWEMSERFLRKWGWLFDGITGVLEATNRWRIERGEEPLTVTVSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQ52</accession>
    <name>E3QQ52_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_08134</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697366">
        <property type="protein sequence ID" value="EFQ32990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097010.1">
        <property type="nucleotide sequence ID" value="XM_008098819.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQ52"/>
    <dbReference type="STRING" id="645133.E3QQ52"/>
    <dbReference type="GeneID" id="24413499"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08134"/>
    <dbReference type="eggNOG" id="ENOG502S0HR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_11_1_1"/>
    <dbReference type="OrthoDB" id="408373at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43689:SF8">
        <property type="entry name" value="ALPHA_BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43689">
        <property type="entry name" value="HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="71"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ32990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="368" mass="39414" checksum="C009552817AD932A" modified="2011-01-11" version="1">MPTTPTTTPRPALDPRKTARSPKWTVLPALSASARDALPYPPGALPGGRDVATAYGNLRVYEFGPEDASERVLLLHGIGTPCLALGGVAAEFVAKGWRVMTFDFFGRGYSDAPLDIPHDARLYTTQILLALASSPLPGWTGNDAFHLLGYSLGGAVAAAFASSHPHLVRSLTLVAPGGLIRSAAHVGWRSRLLYNSEWIPEGVRRWFVARRIAPADPKSGGDAPEKETVDDDEGGTPEWDELRLVGGSRIGEVVRWQMETHPGYVRSYMSTIRHAPVYDRGCEEWRVLGEALSARRAGAAPGLRKGRVLFVLGESDDIVVPGETVWDAETVLGEDAVEVVVLKGGHEVAITKGSEVVGAVVTAWGNNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQA0</accession>
    <name>E3QQA0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Acyltransferase MbtK/IucB-like conserved domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_08182</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the lysine N-acyltransferase MbtK family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697367">
        <property type="protein sequence ID" value="EFQ33038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097058.1">
        <property type="nucleotide sequence ID" value="XM_008098867.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQA0"/>
    <dbReference type="STRING" id="645133.E3QQA0"/>
    <dbReference type="GeneID" id="24413547"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08182"/>
    <dbReference type="eggNOG" id="ENOG502RZMI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027095_1_0_1"/>
    <dbReference type="OrthoDB" id="448427at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016410">
        <property type="term" value="F:N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019290">
        <property type="term" value="P:siderophore biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019432">
        <property type="entry name" value="Acyltransferase_MbtK/IucB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31438">
        <property type="entry name" value="LYSINE N-ACYLTRANSFERASE C17G9.06C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31438:SF1">
        <property type="entry name" value="LYSINE N-ACYLTRANSFERASE C17G9.06C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13523">
        <property type="entry name" value="Acetyltransf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01006">
        <property type="entry name" value="AlcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyltransferase MbtK/IucB-like conserved" evidence="3">
        <location>
            <begin position="352"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="223"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="223"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ33038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="515" mass="58841" checksum="B80F365CD3B7468C" modified="2011-01-11" version="1">MTPQIIHLPDGQKFTVIPVFAGLFFKPHDLNTHNNPFPIGWTVVLNTEDEELAFNDVDSHRSEEDRTHARHRHTHGFRQPTLQNDNLFISSISQPSSTDFKPAASPTRQIAMMLWVTLYWYFHQPQPSPYLTTDASRLTPEEARPKGEWRINIKRDGVLRSKNLMPKLERMGLLSSLDSAVGTNLEDDGEEWSQMFVSRRTFWQIPGRLFLFTLQRRGATSSYIESPASSRPTSPAHTESIHSRHHTPIHSPHQSMGTHFETDVPGPPPNFPIGPFYSSSHLPTYYPPPALMYTITKGIRHPVRRKPGRMGEVFYSRFVPSVGQYLSFRVASFAPEPVPYLGPVGPKPAENSHLTALSDSALLQSWMSNPRVQKFWGDYAPDFLSNVLSSKHSFPVIGMWDGVPFGYFEIYWVKEDILGQKLGSDAGDYDRGVHVFVGEEWARGRVPAWLSSLVHWCLTDDYRTMHVCLEPRIDNVRFHKHLQKAGFAKEREIAFSHKQSYLMKLNRDAWEGPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQP8</accession>
    <name>E3QQP8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08330</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697368">
        <property type="protein sequence ID" value="EFQ33186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097206.1">
        <property type="nucleotide sequence ID" value="XM_008099015.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQP8"/>
    <dbReference type="GeneID" id="24413695"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08330"/>
    <dbReference type="HOGENOM" id="CLU_2670927_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ33186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="75" mass="8187" checksum="75A30E738D9B8674" modified="2011-01-11" version="1">MQLPDRITSNPFNSNKCTILCNANLSDPDFDFFRVSTNAAIDNHAGKRKPPRPLPPSPTPSPPPPCATGLEKEQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3QR20</accession>
    <name>E3QR20_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ATP-dependent protease La domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_08452</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697369">
        <property type="protein sequence ID" value="EFQ33308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097328.1">
        <property type="nucleotide sequence ID" value="XM_008099137.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QR20"/>
    <dbReference type="STRING" id="645133.E3QR20"/>
    <dbReference type="GeneID" id="24413817"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08452"/>
    <dbReference type="eggNOG" id="KOG4159">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013989_3_0_1"/>
    <dbReference type="OrthoDB" id="264917at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16514">
        <property type="entry name" value="RING-HC_LONFs_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="entry name" value="LON domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23327:SF42">
        <property type="entry name" value="LON PEPTIDASE N-TERMINAL DOMAIN AND RING FINGER PROTEIN C14F5.10C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23327">
        <property type="entry name" value="RING FINGER PROTEIN 127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00464">
        <property type="entry name" value="LON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51787">
        <property type="entry name" value="LON_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="224"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="Lon N-terminal" evidence="7">
        <location>
            <begin position="301"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="442"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="22"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="443"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ33308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="551" mass="62440" checksum="7A397289EE58798A" modified="2011-01-11" version="1">MSSDQPRVVESRPSALTSNPAHEAEDERDHGTAERPLLGDQVRDVVRLIQCRKCNRPLQEPVTLPCGRSLCKQCLPETHAREYISYPATPNRLQGFECPYQECGRNHAVGDCGVDVILTKAVNNFKTEMEKARETVTTAEISTHVIIQRPSNEHEDINVEDETTSRVVKGGPLVAVYTLADSGELGYDSNVSFAEVSSFGDEAAAIDNKTFLKVKESVRTEMDCQVCYALFYDPLTTVCGHTFCRSCLHRVLDHSSYCPICRRGLSVSPLLYRESCPSNEYLKTIIETFWADAVLTRGDALAAEALNRHREFDIPIFVCTLSFPMMPTFLHVFEPRYRLMIRRALEGDRTFGMVLPQRPRTANDTHFVEYGTLLRIVNAEYFADGRSLIETVGVSRFRITRHGILDGYLVGKIERLDDISIAEEEDLEANETQHALERFDSAATHQSEDSTTSGPPMTTSEDLAKMPTSELLSFGVSFVERMRQQSVPWLAQRMLTIYGECPNDPALFPWWFASILPAKEYEKYKLLETRSVRERLKICCGWILEWESSSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QR40</accession>
    <name>E3QR40_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cas1p-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_08472</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697369">
        <property type="protein sequence ID" value="EFQ33328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097348.1">
        <property type="nucleotide sequence ID" value="XM_008099157.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QR40"/>
    <dbReference type="GeneID" id="24413837"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08472"/>
    <dbReference type="eggNOG" id="ENOG502RMZP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035994_0_0_1"/>
    <dbReference type="OrthoDB" id="4851124at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179919" description="Cas1p-like protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="340"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="400"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="343"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="405"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ33328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="425" mass="43303" checksum="451946734F85AEB4" modified="2011-01-11" version="1">MHLKHIVAALVAFSSLAAAAPAQDSKAVVRRDDPKQNKDQGQAKNNNDNNSKNNDKNNNNKNNNNNNNRNENINIIQNIIRPNIIVVQENLAAIDQLQRQNEVALAALVQSQLALVTQLQTVKDNIRVNHFKALFPQANTVIVTVTNLVDSRKQGQKNQRYLVNQLLADNGVPGHQTLVMVTDPTPMQISTEQAASSQANAFGAANVQVEDAPAVGSINSSNQAVGGDPNAALNDKSINLAAFDQSAPFGQIGQSLILPAGTLAPQLASVPDPASIILPGQQGLFVQNAATFLSDCATSVAGGNQVLAGVAAQVFSSFQQIAAAQLAGLSGLGIYPANQGQKTPQAAPAPAQAQPAAAQPPAQAVTQPQASAPAAAPTSTSAAAAAPQAASGSGVIIVGSTPGGASAAQPQAAPAAAPAAASQPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRH2</accession>
    <name>E3QRH2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_08739</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697370">
        <property type="protein sequence ID" value="EFQ33460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097480.1">
        <property type="nucleotide sequence ID" value="XM_008099289.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRH2"/>
    <dbReference type="STRING" id="645133.E3QRH2"/>
    <dbReference type="GeneID" id="24414104"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08739"/>
    <dbReference type="eggNOG" id="KOG1721">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049940_0_0_1"/>
    <dbReference type="OrthoDB" id="6910977at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000100">
        <property type="entry name" value="Zinc finger 45-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="266"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="298"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="329"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="104"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="402"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="23"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="402"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ33460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="436" mass="47869" checksum="FE140189CFD35DA8" modified="2011-01-11" version="1">MDLTPPSLTRSPASPAYTCCPSERSSSDYPSPDLTAQQCKITSLYAAGQLYSADLAADADISLPPLDLRTTADWVPLSAMAPSSSSFSIQNVLSEYDQFADYEPPMPVSYESEAFQPHSQTSGPGHHGHPLTDSPEHSPGPLSPRSPTSYAQGEHTSRSLGPRIKMENVNDYGSGIDASNYASPRSMHTPYMADPGPYGSSHHHYLSDTQSSGWPKVEYGAEQYYQNPPAGEPAPLSQAAKRAENMKQNRPRRAPRKMTSFADAQYKCQFKGCDKLFSRSYNYKAHLDTHDEKREYPFPCPVADCNKRFVRKTDLQRHNQSVHMKEKNHRCDYCGRLFARKDTLRRHMEDGCSKRFDVGTCDLRVDAYDGMGSVSRSMGALMHHPMGPGSGPLPPITMSMSMSSGSGLLHPGSSASKGRGAMSGTSDGAHGDNWQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRQ9</accession>
    <name>E3QRQ9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="22">DNA replication ATP-dependent helicase/nuclease</fullName>
            <ecNumber evidence="22">3.1.-.-</ecNumber>
            <ecNumber evidence="22">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="29" type="ORF">GLRG_08826</name>
    </gene>
    <organism evidence="30">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="30" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="30">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="22">Key enzyme involved in DNA replication and DNA repair. Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="31">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="22">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="22">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 22">Belongs to the DNA2/NAM7 helicase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="22"/>
    <dbReference type="EC" id="3.6.4.12" evidence="22"/>
    <dbReference type="EMBL" id="GG697371">
        <property type="protein sequence ID" value="EFQ33547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097567.1">
        <property type="nucleotide sequence ID" value="XM_008099376.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QRQ9"/>
    <dbReference type="GeneID" id="24414191"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08826"/>
    <dbReference type="eggNOG" id="KOG1805">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001666_2_1_1"/>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033567">
        <property type="term" value="P:DNA replication, Okazaki fragment processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071932">
        <property type="term" value="P:replication fork reversal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18041">
        <property type="entry name" value="DEXXQc_DNA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22318">
        <property type="entry name" value="DNA2_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000789">
        <property type="entry name" value="DNA replication ATP-dependent helicase/nuclease DNA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001170">
        <property type="entry name" value="DNA replication helicase Dna2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.320.10:FF:000001">
        <property type="entry name" value="DNA replication helicase Dna2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022765">
        <property type="entry name" value="Dna2/Cas4_DUF83"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026851">
        <property type="entry name" value="Dna2/JHS1_DEXXQ-box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048459">
        <property type="entry name" value="DNA2_Rift"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014808">
        <property type="entry name" value="DNA_replication_fac_Dna2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF433">
        <property type="entry name" value="DNA REPLICATION ATP-DEPENDENT HELICASE_NUCLEASE DNA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01930">
        <property type="entry name" value="Cas_Cas4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08696">
        <property type="entry name" value="Dna2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21123">
        <property type="entry name" value="Dna2_Rift"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 22" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="13 22" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="22" id="KW-0158">Chromosome</keyword>
    <keyword evidence="10 22" id="KW-0227">DNA damage</keyword>
    <keyword evidence="18 22" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 22" id="KW-0235">DNA replication</keyword>
    <keyword evidence="16 22" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="12 22" id="KW-0347">Helicase</keyword>
    <keyword evidence="11 22" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14 22" id="KW-0408">Iron</keyword>
    <keyword evidence="15 22" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7 22" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="20 22" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="6 22" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8 22" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19 22" id="KW-0539">Nucleus</keyword>
    <keyword evidence="30" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA replication factor Dna2 N-terminal" evidence="25">
        <location>
            <begin position="533"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="domain" description="DUF83" evidence="24">
        <location>
            <begin position="745"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2 rift barrel" evidence="28">
        <location>
            <begin position="909"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="26">
        <location>
            <begin position="1100"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="26">
        <location>
            <begin position="1201"/>
            <end position="1268"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="27">
        <location>
            <begin position="1276"/>
            <end position="1504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="204"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="376"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="1550"/>
            <end position="1590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="23">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="23">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="23">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="23">
        <location>
            <begin position="140"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="23">
        <location>
            <begin position="204"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="23">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="23">
        <location>
            <begin position="272"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="23">
        <location>
            <begin position="288"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="23">
        <location>
            <begin position="376"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="23">
        <location>
            <begin position="1550"/>
            <end position="1564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="RuleBase" id="RU367041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF01930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="Pfam" id="PF08696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="27">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="28">
        <source>
            <dbReference type="Pfam" id="PF21123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="29">
        <source>
            <dbReference type="EMBL" id="EFQ33547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="30">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1618" mass="180301" checksum="4A9618FE3E56F08C" modified="2011-01-11" version="1">MPLKKSYSEHVGLPSKNRSWQRSKSNPINAQTSRPLAPVSDKTKSKLNQFQFQSAKASDQENGSGNEDGIRQTRDDIAITPTTKLSWRDLMESNAPKQEDTQISPSERVLWNNELDKSNRSYAAALSPMMPRKGRKRARSSSPMSSPTPHEQPVTPAVNVKKLSEAFKSPRADPTLELWDRFSLTSNGNVTPLGITNPTLANLMFSSSPRNPKNANPSAGDSGLRRAISCGLNWPKRRRVDRSDTPSLTSTLTRETTDSSKNSLVTALLDTVTGSMHENSPPQESEPSVDREDESPSLKKRKTATMRPPTLSPSRKPLGVMKLPHSGNTLDSSVAQDLGIGLKGNMAPAESDYGDVDFDEFDEFDDDTFLEIEASISLSNPKQDARQSTPTPAPPAQPVQAVQQDDVNLDDEFGDLDDDIVEAAETIMESAKVSAASQAPTSTRHAAAETVSVPQQDDLEDVFGDDFGGDFDFDAAELAATQSAQIPHESSTTANSQKPKAIQRYLVTNVLENDYADERGLSRVEKILIVQVDNTKAMRKIHLRDDWYETPAHAKAYVHVIGSFSPSGQCIIDDSHNILILHPDQLISATVVADSFSCMRRAVLQDRVKATSEATAPLVYGTMLHEIFQEALLANQWDLRFLSGVIDKVMEKHIEDLYKIKVSTSIAKEHLQSKMTELSCWATAFVASKPNLDAVVHDRNGKKANMCVSKLLDVEEHVWSPMYGLKGNIDATVQVTMRDGKDVKTLTVPFEVKTGKHANSNHMAQTALYNLLLSDRYDLNIVYGILYYMETSQTMRIPTIRHELRHMIMQRNQLACHIRERSVQLPPMKRSKNMCGKCYAKTSCFIYHKLADDGNAETSGMDKGFDEIVKHLTPKHQEFFLKWENLLTKEEKETQKLKRELWTMVSQAREKVGRCFSDVIIEEGSWSEDLGTSKINRFSYTFLKRVPNPNHSFLESQLAVGEPVVVSDEQGHFALALGYVTSVRKQRISVAVDRRLHNARIKQPGFDETDNQVFASIMEVVPEGCAAGQSHGKIKQAPIRYRLDKDEFSNGMATVRNNLVQTMAEGVFGSREIRRAVVDLVPPRFKAAPTQYVVADRECLNVDQHRAIEKVMSAEDYALVLGMPGTGKTTTIAHIIRALVSQGKSVLLTSYTHTAVDNILLKLKDDKTPILRLGAPAKVHPDVQQFAILAGQPMKSFEQIKEAWHDTPIVATTCLGVGHALFNERTFDYCIVDEASQITLPICLGPIRMAKTFVLVGDHNQLPPLVQNEEAREGGLDVSLFKLLSDTHPDSVVNLEHQYRMCEDVMTLSNTLIYHGRLRCGTEELRFKKLDVPNMNALKSLHYDSSSMLKSGTPKSFCTSMTESCCWLRDLLDSEARVRFINTDTLQPHTREEAKGNRIVNPAEARIVVQLVEGLLTVGVPDGEIGVMTHYRSQLSLLKHGLRGHLGVEMHTADRFQGRDKDVVILSLVRSNESCSIGELLKDWRRINVAFTRAKTKLLVVGSKSTLKGSGKDEMLSKFIGLMEERDWIYDLPPDALDSHVFDDTATQMTASGVSPNKARNTSPRKGFSPRKTPKLALGVDKENRRPQPKRARIGEKVLMKDKVILRDILNDMTNGAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>E3QS15</accession>
    <name>E3QS15_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Kinesin motor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_08582</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697372">
        <property type="protein sequence ID" value="EFQ33653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097673.1">
        <property type="nucleotide sequence ID" value="XM_008099482.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QS15"/>
    <dbReference type="STRING" id="645133.E3QS15"/>
    <dbReference type="GeneID" id="24413947"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08582"/>
    <dbReference type="eggNOG" id="KOG0242">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001485_21_1_1"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01370">
        <property type="entry name" value="KISc_KIP3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000053">
        <property type="entry name" value="Kinesin family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968">
        <property type="entry name" value="CENTROMERE PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968:SF13">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KIF19 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0493">Microtubule</keyword>
    <keyword evidence="5 6" id="KW-0505">Motor protein</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="8">
        <location>
            <begin position="9"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="665"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1005"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="694"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="717"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="739"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="855"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="889"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="936"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="134"/>
            <end position="141"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ33653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1056" mass="115673" checksum="D3A41FCE44ABA5C0" modified="2011-01-11" version="1">MVADPNAASITVAVRVRPFTIREAAQLTRNDEGTVFLGDGSLAAAPPKLQRGGIRPVIKVVDDRCLVFDPPEDNPVHRFGRSVVPNGKKVKDQTFMFDRIFDENATQNDVYEGTTKQLLDSVLDGYNATVFAYGATGCGKTHTITGTAQHPGIIFMTMQELFEKINERSQDKTTEITLSYLEIYNETIRDLLIPGGSKQGLMLREDSNQAVSVAGLTSHHPKNVQEVMDMIVQGNEWRTVSPTEANATSSRSHAVLQINVAQKDRNADVNEPHTMATLSIIDLAGSERASATKNRGERLLEGANINKSLLALGSCINALCDPRKTNHVPYRNSKLTRLLKFSLGGNCKTVMIVCVSPSSVHFDETQNTLRYANRAKNIQTKVTRNVFNVNRHVKDFLVKIDEQIALINELKAQQKDAEKIFYAKFRKQLEKRDSVAREGIQRIRVAYDNSANDRRDKINNMKKLRAFERRIGLLSAWIASFDTVCDQRGDEDSMPASLVAIRKTAQGILVELEHSRHHIHQKLEHTNWERSIDTALHHSIKQLPGGDADAAEIYTLTREAELLKANFGRDANREVLEMDKAGDAAMVQVLLTAQFDILASLEDTLEMNEEDAVAHAKRIINRLLEAGFTAASHVVKPDGAMIPVEKFSPSKRGTPKRKKAVLNNLNNTSPVRQPAFAPPADTAPQPHVSPLKVSPRRKKTGAPRSPRKGVSFSPVKRKSEAKRAVRWRDDETEQGTLADFEKTPKKFETTPEHNSPGKRSPKMPPLPSYLRTASPNPDKSPTLELEGSSSIPPAKPNRFQAGFLSKGRVSSIGSGSPTMPVPTMSLPLGLSPSSDNGGRVSPLRALDVQRSSNLSPPAFRSRIARASPPPRTSLSGSVSADENNPPPSYNASGSESESPSIDPRKLRSAMNSMKKVRGEHRRVSSIGGSTGGNARRISSVSSISTNHRASLSFSGPLASNSNGISRQRRASAERRLSPPITCSPPDVKSDRAFTAGQARRMNLGGSLRLEGGSPQAPPSRMVSADFKNRRITIGSLAATGKIEKSHAPRPSVAGWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QS77</accession>
    <name>E3QS77_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tat pathway signal sequence</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_08960</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ustYa family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697373">
        <property type="protein sequence ID" value="EFQ33816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097836.1">
        <property type="nucleotide sequence ID" value="XM_008099645.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QS77"/>
    <dbReference type="STRING" id="645133.E3QS77"/>
    <dbReference type="GeneID" id="24414325"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08960"/>
    <dbReference type="eggNOG" id="ENOG502T8GX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_963151_0_0_1"/>
    <dbReference type="OrthoDB" id="3687641at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043386">
        <property type="term" value="P:mycotoxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365:SF6">
        <property type="entry name" value="OXIDASE USTYA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365">
        <property type="entry name" value="YALI0B05434P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ33816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="289" mass="32949" checksum="FBCFFA626F8AAA58" modified="2011-01-11" version="1">MESDSSCSSVKLLSADGDTSGTDHSQICHRCEGKIVKDTSRMHFSGLRLVMMFGGLQLLLLVFGGLVFHSFRADERNPKDMDPHGYFALEQYNATDKAYDIVDAADPSPEADRFWHDLRKADGIVAVDGGWAQRVNLPSTVDHPHEPHLRLYQINVFHSLHCLYRIRNRLISNFTLDQWPRNDIHTMHCLDHIRNDLMCNADISLSGSDEFVSFNRHGHDQKCRDLGAIQAWAREHSWPGYSDYLESVIGYDFNEAERVNMATAGKGHWNKANSTLDKQTGKIELWFED</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSB8</accession>
    <name>E3QSB8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Myb/SANT-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_08889</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697373">
        <property type="protein sequence ID" value="EFQ33745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097765.1">
        <property type="nucleotide sequence ID" value="XM_008099574.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSB8"/>
    <dbReference type="STRING" id="645133.E3QSB8"/>
    <dbReference type="GeneID" id="24414254"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08889"/>
    <dbReference type="eggNOG" id="ENOG502RRE4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031888_0_0_1"/>
    <dbReference type="OrthoDB" id="5307821at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024752">
        <property type="entry name" value="Myb/SANT-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46929">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46929:SF3">
        <property type="entry name" value="MYB_SANT-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12776">
        <property type="entry name" value="Myb_DNA-bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb/SANT-like" evidence="2">
        <location>
            <begin position="28"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="210"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="313"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ33745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="420" mass="46371" checksum="5EE2C5A104EEA74B" modified="2011-01-11" version="1">MSDDEFTGPDGQPGSAGGDRDKRAPRFSWTPAYEATFFRSLCDSVQLGLRENHSFKADAWDRAATALREKHGAYPTKSHLVNKSDNARKKFRLWRGLREDPEFLYNPTTRTVTASEEAWKAHIEKEPLSRALRGRPFDHEQFMEVLYPDVVGSGGAPKRIMKPKRKGPDVIQGSEDPDMPGTAVLDLQVEPPYQPPSQSGTNQQAQPRGSVSQSPVAQVQQPMIPQKQAQPQQQQQQQPQQRPTSTAIPPRTHIAGTSALTPPEETATGRKRFPQQAPTSDAGGKAPTAPMGPPTQPAEKRRRISGYTNPAQASGSGASSNHGNDASSSSMASAGKQLMEDGLIRIADALRGRSPPKWPEQAIDIFFRDFSDEDMDLQLKIAEKALADDNKAMIFCKMSPALRKHWVKRLRELHNNSRNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSX0</accession>
    <name>E3QSX0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Dihydrodipicolinate synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_09102</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DapA family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697375">
        <property type="protein sequence ID" value="EFQ33958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097978.1">
        <property type="nucleotide sequence ID" value="XM_008099787.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSX0"/>
    <dbReference type="STRING" id="645133.E3QSX0"/>
    <dbReference type="GeneID" id="24414467"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09102"/>
    <dbReference type="eggNOG" id="ENOG502QWNS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049343_0_2_1"/>
    <dbReference type="OrthoDB" id="191315at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008840">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00408">
        <property type="entry name" value="DHDPS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128:SF52">
        <property type="entry name" value="4-HYDROXY-2-OXOGLUTARATE ALDOLASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="DIHYDRODIPICOLINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="2">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001365-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001365-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ33958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="333" mass="35111" checksum="D85A9E7C75952D1D" modified="2011-01-11" version="1">MSPSASGNSYHNDDDSGHRSRPALMPGLYVPTVAFFRSDDSVDVETTTSHAVRLAKAGVAGLVTHGSNGEAVHLDHAERQLINQTTRAALDSAGRSNLPLLVGCGAQSTRETIQFCKEAGASGGDYALVLPPAYYGGLLTTEHILQHFRDVADASPIPILIYNYPGACSGLDLNSDTIIALSEHHNIVGVKLTCGNTGKLARIAAATAPKKGDTGAPFRTFGGSVDFTLQMLVVGGHGIIGGTGNIAPLACMKVMDLWNEGKLIEARELQAVVARGDWTAIQGGFVSVKAALQEYYNYGGLPRKPCALLEGERLAKQLDEFAELVAVEAALQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTL1</accession>
    <name>E3QTL1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09430</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_008100115.1"/>
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    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09430"/>
    <dbReference type="eggNOG" id="ENOG502S5ER">
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        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
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    <keyword evidence="2" id="KW-0808">Transferase</keyword>
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            <end position="196"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="214" mass="24394" checksum="3492A53494A70095" modified="2011-01-11" version="1">MASQDSTKIPLEIVTPRLIIRTAVQSDAEAYLSYLTNADNFPFQEPEKDLKIDRLRTRIDKFADFTRKGENGWIVILLRDTNELIGNGGYNTFESVDPSEFLSGTTTLPPGEKRMTDLGIGIDHKHWRKGYGLEALEGLIEHARTNLGCELFRTETGDDNQPWRSLMRTAGLGEFEARNKASYDASQEVWVWKFDAGHWNQSVNKLKEDGKWLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
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        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
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        <name evidence="2" type="ORF">GLRG_09510</name>
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        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
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            <taxon>Hypocreomycetidae</taxon>
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            <taxon>Glomerellaceae</taxon>
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                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
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                <person name="Neumann U."/>
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                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
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                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
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            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
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    <dbReference type="Proteomes" id="UP000008782">
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    </dbReference>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EFQ34366.1"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="95" mass="10382" checksum="4F543605106A25DC" modified="2011-01-11" version="1">MGSPSGPLRPRASSNFMGLRATGFPPSMTPQEKHLFSDRVNSATTRLSSTMAASETPEGYIFVVYFHKTSAADALAALRAADIRVRGHEIQFSWH</sequence>
</entry>
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    <accession>E3QU53</accession>
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        <submittedName>
            <fullName evidence="4">Leucine Rich Repeat family protein</fullName>
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        <name evidence="4" type="ORF">GLRG_09535</name>
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    <organism evidence="5">
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        <lineage>
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            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
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    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
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            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
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        <property type="component" value="Unassembled WGS sequence"/>
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    <dbReference type="GO" id="GO:0005737">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
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        <property type="entry name" value="Leu-rich_rpt"/>
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        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
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        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF27">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="886"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1161"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="129"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="157"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="203"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="260"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="448"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="923"/>
            <end position="940"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ34391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1182" mass="126743" checksum="22D95DA12ED1F603" modified="2011-01-11" version="1">MDGKQASARSSSGIPRLSRLPLPKPTPTPTPATVRPSPSREGLNSGLRNPRLRPAASREQLGPVVAPKQPVSSRIASKPPTREIQPPSSRKSELRVSPAALRTSRSVTRLKQKEPSFNKPPTPPEEPETTALSRSTSLSRRSSALHTLTPEFEPAVPDLPPLPSATSPPPATDDAASHDLPGFDTPKAKSLKPRPSLSERTIETLQQLQSSPTLSKKTSSFFDPEGTMRPRSRAGSGHSRPGSSYASDGSVRPTSRDSRPGSSSAADENPFANIQQAATSPRLPPASVERTPSRRVSSIRSLRPPAIKATPQPSPSGLPSATGIPLAQTPSPTRTTGIMPPPKTGATAIASPSLKTRASATGLYKKPSLSSMSRASPAAAVLSPPRKLMPAKSYGSLRKPTPSKIGSPAPAASTEADEESVARKSSNALREQIAKARAAKRAADRQAAEAASAPAPEPTSEAPSNQTDPPIVPDDSGFNFGIAVTTDTLDANDPFNTSDPFNTKRSDVSQQKVIQQRLAAARNSGRLNIAAMGLKEIPAEVLKMYDMESMGTYDGSWAETVDLTRFVAADNELETIDDAIFPDVTAEEMAQDEDSNGNIFGGLEAMDLHGNALISLPMGLRQLPLLTSLNLSQNRLANNCLQVITQVKALRDLKLANNLLYGPLDPTFANLENLEIFDLHGNKVSALPPVIENLSRLRILNLGENSFEALPFTSLAKLPLTELLMKKNKLTGTLIQDGVETLPNLQMLDISCNQLTRLVPSGSTISLPSVHQLVLSMNRLQELPDVTSWTSLMTLAADGNAIPEFPIGFTGLTKLRHADFSANDIRVVPPEISRMDNLTLIRLAGNPLRDKKFVSATTEELKDVLAARLEPPEPFQEVDAVIIPDDAPSNTLAEPHEIHPAAKPAPAETTARDIAQSDEDSFATPPSSSPTSPASTRSRTLANETWPVKQGLLDRSNTKSSSLHPVICSKVAAENKVIEVQLHHNLLTCFPNSLSFFADSLAALSLAHNQLVGESYLTEELDLPVLRELNLVSNHITSLSPLTTHLHAPQLEKMDVSLNRITALPPNLRAVFPRLVVLLAANNHLIDLDPVTIQGMEVVDAGNNDIAHLNPKLGLLGGSGGLKRLEVSGNRFRVPRYNVLERGTEATLRWLRGRVPVAEMASWKEGQGDPDDASDTSLADVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QU67</accession>
    <name>E3QU67_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transcriptional regulatory protein RXT2 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_09549</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697380">
        <property type="protein sequence ID" value="EFQ34405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098425.1">
        <property type="nucleotide sequence ID" value="XM_008100234.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QU67"/>
    <dbReference type="STRING" id="645133.E3QU67"/>
    <dbReference type="GeneID" id="24414914"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09549"/>
    <dbReference type="eggNOG" id="ENOG502S5XA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030828_0_0_1"/>
    <dbReference type="OrthoDB" id="2405722at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033698">
        <property type="term" value="C:Rpd3L complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039602">
        <property type="entry name" value="Rxt2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013904">
        <property type="entry name" value="RXT2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28232">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATORY PROTEIN RXT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28232:SF1">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATORY PROTEIN RXT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08595">
        <property type="entry name" value="RXT2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcriptional regulatory protein RXT2 N-terminal" evidence="2">
        <location>
            <begin position="37"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="415"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="433"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ34405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="464" mass="51296" checksum="22ECBA3E011F35DD" modified="2011-01-11" version="1">MATQQILFAETVAAMKKALKRKSYESDSDDEIDHYGNRGHKLKKRALFSHQGQLAPPSGPEVYNEVIDYAGQQRTIISRNPPIVDDEGYEIDSDDEEERIQEAVSAATELDPYANIRIEQILAPLTASTDLPSHPTLSKPFTAKTLDEIAEQSCQVRRKENASLWRVRHLFTRLCGDYTWVPCGMMVGPDDADLYSSDYVERGYARKTKTLASRETEAAASGTVNGDAKPERALNGTNGESSGDKQSSDGDVTMADAGSDDKSAKVDTPTAGEASRPTNGQTSRMDIAQKAGADESIADKKQKQKAVDVEMHEGNAAPPSQPGTDMLDHNGTHAPSIASEEVDETFVHPFFRPPPNARPDRDVGLPEAEAEDIRRLLALYVQKQEEVCRGAMKLHEGLLKANRLRKTVLHWSKAEAHSGPNRDMSDGEDWYDKEEWGLTEDLKKGQDDEEEDTGTVAKKTRNRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QV19</accession>
    <name>E3QV19_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sister chromatid cohesion protein DCC1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_09853</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697383">
        <property type="protein sequence ID" value="EFQ34709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098729.1">
        <property type="nucleotide sequence ID" value="XM_008100538.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QV19"/>
    <dbReference type="STRING" id="645133.E3QV19"/>
    <dbReference type="GeneID" id="24415218"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09853"/>
    <dbReference type="eggNOG" id="ENOG502SA0V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116847_0_0_1"/>
    <dbReference type="OrthoDB" id="5199543at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031390">
        <property type="term" value="C:Ctf18 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007064">
        <property type="term" value="P:mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019128">
        <property type="entry name" value="Dcc1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09724">
        <property type="entry name" value="Dcc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ34709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="131" mass="13997" checksum="A78CE87489FA633B" modified="2011-01-11" version="1">MSTQDVGIPLTHAPDSRGYRLMELPPELEALLTAEDAPIITLTSTPTTALLKARDKTYKLLQKNTSNSLILLAPHATTPLGSDTSAAVGLGAIATLHETIELVAQAEPQTISNLKNTGSKGKWHEKFGRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QV53</accession>
    <name>E3QV53_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09887</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697383">
        <property type="protein sequence ID" value="EFQ34743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098763.1">
        <property type="nucleotide sequence ID" value="XM_008100572.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QV53"/>
    <dbReference type="STRING" id="645133.E3QV53"/>
    <dbReference type="GeneID" id="24415252"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09887"/>
    <dbReference type="eggNOG" id="ENOG502S8W5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010595_9_3_1"/>
    <dbReference type="OrthoDB" id="417697at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="370" mass="39982" checksum="8E1D3056A90CBD88" modified="2011-01-11" version="1">MSAVQITASITDSLKELESALAPSNQVKLELDPSSWSSEASSYASDNTSEYAFNDSSSSSDDEMPPVSTVKGLVNNSIVLRESHNNPDSPYCLPADSKEKLRLDKQHNFIRDHICDGRLVLDDSLTLDKGALVLDLGTGSGAWASDLAQYLPAGVEIKGFDISNRLFPPNAPNMTFAIGNVLDLPDHLDSRVTLAHQRLLIYALRRHEWSRALASIRNTLIPGKGVVQLTEVLTPAGNPGAAQEKFQALLSSIGLKRQLLLDCGELLPILLAEAGFVDIQKRTIKVRLGGAGGVKGMKAAACRGGAFRGMRDSVLSDGGYGIVNSAEEFDKLVNRVVTEWESNECYAFYYTITARRPSLGLTPPLSPDHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QV68</accession>
    <name>E3QV68_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09902</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697383">
        <property type="protein sequence ID" value="EFQ34758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098778.1">
        <property type="nucleotide sequence ID" value="XM_008100587.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QV68"/>
    <dbReference type="GeneID" id="24415267"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09902"/>
    <dbReference type="eggNOG" id="ENOG502RAKB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1240036_0_0_1"/>
    <dbReference type="OrthoDB" id="4803291at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.60.10">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036673">
        <property type="entry name" value="Cyanovirin-N_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180999" evidence="1">
        <location>
            <begin position="18"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="223" mass="24442" checksum="EB6EA3CE8530257E" modified="2011-01-11" version="1">MLATVLLTLLFSTLVLAQSDKPDAPGYDRWSEGCLHKLNGLMAEKGVKDQPGYDTFGGTCKGTRVVMEKLRAVSVREEWMLYSCCRKKNGEFEHVRKLPLQNCLAFNDAGGGTLTWQKMMRLADACKDCKVVGKSQNGAPGAHLRCSCEAPRQAAKTFELPIHANMWAEGDVGGRQLSRYPCGVSTGSLECGWAFCVHNAYQHIDPTGHWHGPGSPDANDPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVC9</accession>
    <name>E3QVC9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_09961</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697384">
        <property type="protein sequence ID" value="EFQ34817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098837.1">
        <property type="nucleotide sequence ID" value="XM_008100646.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVC9"/>
    <dbReference type="STRING" id="645133.E3QVC9"/>
    <dbReference type="GeneID" id="24415326"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09961"/>
    <dbReference type="eggNOG" id="KOG1001">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1896057_0_0_1"/>
    <dbReference type="OrthoDB" id="448448at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF22">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ34817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="134" mass="15663" checksum="5049016508BAF028" modified="2011-01-11" version="1">MISGSHQYEEPQFYGGIIADPMGLDKTLTMIALWKAEYGTQTSPLFAVRWKTIILDEAHYIRNESSRMARADRLSDLATIVKFFRVHPYTDTRQFDTDLSQLWKPKGTIDLHLRHDKLCPIDFAREERVVYDKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVT9</accession>
    <name>E3QVT9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">thioredoxin-dependent peroxiredoxin</fullName>
            <ecNumber evidence="2">1.11.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_10121</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O</text>
            <dbReference type="Rhea" id="RHEA:62620"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.24"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.24" evidence="2"/>
    <dbReference type="EMBL" id="GG697386">
        <property type="protein sequence ID" value="EFQ34977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098997.1">
        <property type="nucleotide sequence ID" value="XM_008100806.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVT9"/>
    <dbReference type="STRING" id="645133.E3QVT9"/>
    <dbReference type="GeneID" id="24415486"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10121"/>
    <dbReference type="eggNOG" id="KOG0852">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042529_21_1_1"/>
    <dbReference type="OrthoDB" id="185659at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03015">
        <property type="entry name" value="PRX_Typ2cys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000003">
        <property type="entry name" value="Peroxiredoxin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050217">
        <property type="entry name" value="Peroxiredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019479">
        <property type="entry name" value="Peroxiredoxin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10681:SF171">
        <property type="entry name" value="PEROXIREDOXIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10681">
        <property type="entry name" value="THIOREDOXIN PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10417">
        <property type="entry name" value="1-cysPrx_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 9" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="7 9" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="11">
        <location>
            <begin position="4"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity" evidence="10">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ34977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="215" mass="23811" checksum="4B4B2BA6994D707F" modified="2011-01-11" version="1">MSSAFVQRPAPGFKATTVFPGGEFKDINLSDYLGQWVVLLFYPLDFTFVCPTEIIQYNDALPRFRAINTTVLGVSTDSHFSHLAWTEKPRKQGGLGSDLELPLVADKSHKISRDYGVLIEEEGVALRGLFIIDPKGILRQITVNDLPVGRNVEETIRLVEAFQFTDEHGEVCPAGWQNGSKGMKADPKGSLEYFAAQDETNGHANGNGQKRLRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWS7</accession>
    <name>E3QWS7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Small-subunit processome Utp12 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_10459</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UTP5 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697391">
        <property type="protein sequence ID" value="EFQ35315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099335.1">
        <property type="nucleotide sequence ID" value="XM_008101144.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWS7"/>
    <dbReference type="STRING" id="645133.E3QWS7"/>
    <dbReference type="GeneID" id="24415824"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10459"/>
    <dbReference type="eggNOG" id="KOG4547">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038849_0_0_1"/>
    <dbReference type="OrthoDB" id="30195at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007148">
        <property type="entry name" value="SSU_processome_Utp12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052414">
        <property type="entry name" value="U3_snoRNA-assoc_WDR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44267">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44267:SF1">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04003">
        <property type="entry name" value="Utp12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Small-subunit processome Utp12" evidence="5">
        <location>
            <begin position="168"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="275"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="36"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="289"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="344"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="398"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ35315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="407" mass="43333" checksum="A71BE7047103BA0B" modified="2011-01-11" version="1">MSSRRKSSGKFAAPVVKSTPKASKTTIDESRAAVSATDSLQAALTGNNEAIEISSDEDSDEDVSDEEMGAPDAEAGDATETVNGKDDDAENPTQQQPKTDAEGAEDEEEAGSPTFGELLRGTIDVPAILSQQGDSSKAVVSQSSRKNLAPPSLSSLSTVLTQALKTEDTDLLESCLQINHLETIQQTIERLDSSLAGILLTKLASRFHRRPGRAGSLMTWVKWTLVAHGGALAVQPKVLERLVSLQKVLSERSRGLPSLLALKGKLDMLEAQMQLRNGRQRRGGAGQTDDADEDDEEEGAIYVEGEEDAEEDADAANGPGSRKAMLAADDDDEDVPATNGFVGDSDDEDDDEDAMAAEDESSGEEVVDEDDVDYEDLEDSDDDDDSDAEAAPPAKVQKTASSFAKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXH4</accession>
    <name>E3QXH4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peptidase M20 dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_10706</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M20A family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697395">
        <property type="protein sequence ID" value="EFQ35562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099582.1">
        <property type="nucleotide sequence ID" value="XM_008101391.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXH4"/>
    <dbReference type="STRING" id="645133.E3QXH4"/>
    <dbReference type="GeneID" id="24416071"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10706"/>
    <dbReference type="eggNOG" id="KOG2275">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021802_3_0_1"/>
    <dbReference type="OrthoDB" id="3064516at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05652">
        <property type="entry name" value="M20_ArgE_DapE-like_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050072">
        <property type="entry name" value="Peptidase_M20A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43808">
        <property type="entry name" value="ACETYLORNITHINE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43808:SF30">
        <property type="entry name" value="ACETYLORNITHINE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="Bacterial exopeptidase dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00759">
        <property type="entry name" value="ARGE_DAPE_CPG2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180953" description="Peptidase M20 dimerisation domain-containing protein" evidence="6">
        <location>
            <begin position="19"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="7">
        <location>
            <begin position="228"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ35562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="418" mass="44767" checksum="001C9902E925A33F" modified="2011-01-11" version="1">MYISPFLALGSVLPLAATSRIQQPLAADSPPLTPHSFSSTSSSAPAWRDDLLSLHRSLIEIPSVSGNESAAGRFLVDYLTGRGYVSSLQFLPPRNNSSNETPRFNVLAWKTNQRQPEPRVVVSSHYDVVPPHIPYGISDEHITPGTRISGRGSVDAKASVAAQIIALEDLFNADKVNPDDVMLLFVIGEEDTGDGMRFFSDSLQEADPPVRFDSVIFGEPTEGKLACGHKGGVFCDITAKGVAGHSGYPWLGKSANEIMIKALAKIITTDLGSTEKWGNTTVNIGQFNGGVAQNVIPAAALARIAVRVAIGPEKDGGNIVKDRIQKILDETDSESLEMTCTHGYGVVEANCEVDGFETLVANYGTDIPNLKGSHTRYLYGPGTILVAHGRDENITVAELEEAVGGYQKLILHALQDSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYA7</accession>
    <name>E3QYA7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10954</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697401">
        <property type="protein sequence ID" value="EFQ35845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099865.1">
        <property type="nucleotide sequence ID" value="XM_008101674.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYA7"/>
    <dbReference type="GeneID" id="24416319"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10954"/>
    <dbReference type="eggNOG" id="ENOG502T4IG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_608329_0_0_1"/>
    <dbReference type="OrthoDB" id="4851746at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="110"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="427"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="450" mass="48975" checksum="470C2C1884F46832" modified="2011-01-11" version="1">MDVRVKNEESDNPVKVDEADVPIDRGEQDVQVKAEEEVSALTPPSPSQLRCALSVGASRISPRYQRSSSNLPMQQTTARPARLAVHSNASANAPSAVSANLMACQGQAHASLPAPSSASGSGTTTNLPPTRSSGVRQLATTKLQSFAVKTKSVSRHQPESRSGPNLILDFLAIPLSTPPSQSDQYIHGGRRPVSPMKTMKPMTGPVHPVAAPFCKETRARLDDKPHEDWIYTTSTGSIKKLPQLGSCGPWQVSLPSKMDTAIHIDPYIDRLSHLLNVQIESTKSPPSIHVKLFKSQLAEQAKHSYLLEEHTAMKWKAWAVLAAWVDHLVRRGAPPAIPPIDLVSFVRNKLLAEGRRARETAVDLLHDRQGVVLLPKGHGTLQMPRLTPADLIPLSKPSPPGTRKPSLMPTKRLPQASKYGHKHLLTDDSSSSSSSDSSPEVQAKRLRHRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZH4</accession>
    <name>E3QZH4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Arginase</fullName>
            <ecNumber evidence="2 11">3.5.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_11407</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 11">
            <text>L-arginine + H2O = urea + L-ornithine</text>
            <dbReference type="Rhea" id="RHEA:20569"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16199"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="EC" id="3.5.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="11">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nitrogen metabolism; urea cycle; L-ornithine and urea from L-arginine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9 10">Belongs to the arginase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.3.1" evidence="2 11"/>
    <dbReference type="EMBL" id="GG697416">
        <property type="protein sequence ID" value="EFQ36262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100282.1">
        <property type="nucleotide sequence ID" value="XM_008102091.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZH4"/>
    <dbReference type="STRING" id="645133.E3QZH4"/>
    <dbReference type="GeneID" id="24416771"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11407"/>
    <dbReference type="eggNOG" id="KOG2965">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039478_6_1_1"/>
    <dbReference type="OrthoDB" id="9992747at2759"/>
    <dbReference type="UniPathway" id="UPA00158">
        <property type="reaction ID" value="UER00270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004053">
        <property type="term" value="F:arginase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006525">
        <property type="term" value="P:arginine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000050">
        <property type="term" value="P:urea cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd09989">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.800.10:FF:000009">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.10">
        <property type="entry name" value="Ureohydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014033">
        <property type="entry name" value="Arginase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020855">
        <property type="entry name" value="Ureohydrolase_Mn_BS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01229">
        <property type="entry name" value="rocF_arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43782">
        <property type="entry name" value="ARGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43782:SF3">
        <property type="entry name" value="ARGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00116">
        <property type="entry name" value="ARGINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01053">
        <property type="entry name" value="ARGINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0056">Arginine metabolism</keyword>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 11" id="KW-0464">Manganese</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ36262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="326" mass="35309" checksum="5E3A25ED2BCBBA37" modified="2011-01-11" version="1">MHTSMVKSKFLSNPEDLGVVAVGFSGGQCKPGVDAAPKALIESGLLTQLRDELGYQLHGHDEVHLYTDLVPAEDPPYRNMKNPRAVSAVTERIADQVYQQSRLGRLTLTLGGDHSIAIGTIAGSARATRERLGREIAVIWVDAHADINTPETSGSGNVHGMPVAFLTGLAKEDRPEYFGWLRDEHRLSLKKLVYIGLRDVDPGEKRILRENGIKAFSMFDIDRYGIGRVMEMALAHIGSDTPIHLSFDVDALDPMWAPSTGTPVRGGLTLREGDYICECVHETGSLVALDLVEVNPSLAAEQEGAASETVRAGCSLVRCALGESLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZU0</accession>
    <name>E3QZU0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Pyrroloquinoline quinone-dependent pyranose dehydrogenase beta-propeller domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11523</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697421">
        <property type="protein sequence ID" value="EFQ36378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100398.1">
        <property type="nucleotide sequence ID" value="XM_008102207.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZU0"/>
    <dbReference type="STRING" id="645133.E3QZU0"/>
    <dbReference type="GeneID" id="24416887"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11523"/>
    <dbReference type="eggNOG" id="ENOG502QPZ1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039534_0_0_1"/>
    <dbReference type="OrthoDB" id="507128at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054539">
        <property type="entry name" value="Beta-prop_PDH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22807">
        <property type="entry name" value="TrAA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyrroloquinoline quinone-dependent pyranose dehydrogenase beta-propeller" evidence="1">
        <location>
            <begin position="14"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="279" mass="30312" checksum="A76A97DFED70352E" modified="2011-01-11" version="1">MTTAWSYAYDAKAQAGSDGNFDYDSINKEVARAVVKVFDMRSVPVGGYAYASQGWLLGYGLRNEVALATDGNNAVWGVENSGDEFARTVNGQSYDIHKDNPADELNFLGNPSEPNEQWYGYPTCFTVWEPSVITDKSLAVGGQFVVAPNDTFNDDSCTQRSVAPRLSFQAHSAPIGAAFDASFQNLYVTLHGSWNRSPATGFKVSVIPFTKLSNGNYDPVAAADSKTGCIDILWSTNVDTCTGSTCFRPSGITWDRSFSRLFVASDNDAEGELFILTKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3R029</accession>
    <name>E3R029_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_11594</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697425">
        <property type="protein sequence ID" value="EFQ36449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100469.1">
        <property type="nucleotide sequence ID" value="XM_008102278.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R029"/>
    <dbReference type="GeneID" id="24416958"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11594"/>
    <dbReference type="eggNOG" id="ENOG502T5W6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2960637_0_0_1"/>
    <dbReference type="OrthoDB" id="273010at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ36449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="59" mass="6166" checksum="AD3A8E0547AE4678" modified="2011-01-11" version="1">MEQFGLAAAHSGAINHIHAVHFGPAALDIAREARLAVTVVVVGWVAVTGIRALSDRGKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3R061</accession>
    <name>E3R061_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11644</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697430">
        <property type="protein sequence ID" value="EFQ36499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008102328.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R061"/>
    <dbReference type="STRING" id="645133.E3R061"/>
    <dbReference type="GeneID" id="24417008"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11644"/>
    <dbReference type="eggNOG" id="ENOG502RVVQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_467851_0_0_1"/>
    <dbReference type="OrthoDB" id="5234071at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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            <begin position="1"/>
            <end position="25"/>
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        </location>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EFQ36499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="598" mass="64860" checksum="1B4A45C4C0768C1D" modified="2011-01-11" version="1">MVSFFGLKLGADKKKKAEKAAEQKPQWKKIDQNLLGQGQFFGKDLDRPVPVDGSRPGTAMSSKSFIASFRQPKAPYMNGGSSSLVDLGAPGGGKGIRPVGSEANLNMRWNNSSVTSLQNIASPPIITGGSRPGSRAGTPTSISRKVWVNPLDVHFARDNAGSRSEGTLSPAPSAAPSGYHSTTSLSPLPTPTVANAPRSPLGQFEFNLNPSETSKDDKLAPAPLSPSKAYPSPPLSVNGSLPRLRTDFKPKTSVSTVHEVHQPRPAALPSPTASAGRCSDEEQHFYPRPIIQNVAAKRDTLTIITPRRQSLSMDIDEDPTALSFGMREEQSPTVPVSPPPKSARRPRPPEMKSLPQVPRDAGPPPPRPQQVPYEGPLRITAQAPGDVFIVRQPTGWDLREKTKFEPTGRVDSDARDRLNLDYRERSGPDGRDRRDYEGRTRNDRLYLPQGYLGPPPVSRRVAPGEGERSYGITPANRRRPPPPVELQRKAPSPQPRPPASDDRDIQQGSFDMVSPRMQTPQPSTPEGLTPEPLTDTNWPLPSPLASPTFGTGHRPHTPSEGSEVQMSPGREGALDARRPDFGLRAPTGIADEFRVGFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>E3R099</accession>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    <gene>
        <name evidence="2" type="ORF">GLRG_11672</name>
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        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
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        <lineage>
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            <taxon>Ascomycota</taxon>
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            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
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        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="54"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="78" mass="8300" checksum="9E84B9A0E16F9D66" modified="2011-01-11" version="1">MDDMPGVSCLRSVVASQQTSREARTNLDLVQDLDRSKPTLATPFNPSSVQGTSGTTTTTTTTTTTTTTTTTIIILLLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0F0</accession>
    <name>E3R0F0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_11733</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
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        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
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        <property type="protein sequence ID" value="EFQ36588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="GeneID" id="24417097"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11733"/>
    <dbReference type="eggNOG" id="KOG0254">
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    <dbReference type="HOGENOM" id="CLU_000960_22_1_1"/>
    <dbReference type="OrthoDB" id="10021397at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS toxin efflux pump (AflT)"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS toxin efflux pump (AflT)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF199">
        <property type="entry name" value="MFS EFFLUX TRANSPORTER INPD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="250"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="295"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="322"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="362"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="403"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="429"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="453"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="492"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="560"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="100"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ36588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="597" mass="64125" checksum="202594A38EF5DC32" modified="2011-01-11" version="1">MFDAQPSVAPSLLTIPTFLQSRASTLAPSDSSYDDIMEKGLTISSSTPSLQNIHTHITSLRSKSGTALPAQTSITRSRKTLTVEDARHAEYPGGMKLALIVAAACFSVFLMALDNCIIATAIPRITDEFNSLNDVGWYGSACLLTTASVQLLFGKLYSFYSIKRIYLGTIGVFEIGSLVCGIAPNSITLILGRAVVGLGSAGIYAGALIILAHSVPLEKRPIYTGVVSSMWGISSVVGPLLGGFFTDNLTWRWCFYINLPVGAATVLVIILFFPDPVRIIPRETWRTRLAQMDPLGNLLFMPSVVCLLLALHWGGIVCPWSSARIISLLLAFCMGMLAFLYLQYHGQENATIPPRIFKKRTVWSSSLFSFNLGAAFLLSVYYLPIWFQSVQGVSAVNSGVRNLPMLVGNLIFSLVAGSAVTHWGYYTPFMLLSSVFMSIGYGLITTFSPETPSVMWIGYQIIAGVGVGVGMQQPLIAVQVVLDMADVATGTAIVIFAQQIGGAIFIAIGQTVFTNKLVERLPLHVPTLDPHSVVATGVTAIRKTVDAELLPAIAHAYSDALVQTFLVSTVAATATIVGAGFVEWKSVKGKTVQVSMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0I5</accession>
    <name>E3R0I5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11768</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697446">
        <property type="protein sequence ID" value="EFQ36623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100643.1">
        <property type="nucleotide sequence ID" value="XM_008102452.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0I5"/>
    <dbReference type="STRING" id="645133.E3R0I5"/>
    <dbReference type="GeneID" id="24417132"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11768"/>
    <dbReference type="eggNOG" id="ENOG502R0Q2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_560210_0_0_1"/>
    <dbReference type="OrthoDB" id="4823581at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="501" mass="55089" checksum="CA337D68882AE838" modified="2011-01-11" version="1">MAPSSIPANPTQWHAAAREANLENTSLGSMDEHRAFSGSTMPHAAFLQLRAIWPHRLPSIAAMQNLQCGGFFDRNDLHLAERIIEHKAGTKGALEAFIKEISSPSTPNPRPGGDGANDPDEEEAFSDDVLGPFLPILSLWKLLRSPGPASPALQATPAVIFSSHNEFGRDIAKLDYAKPAVGSCEIECEDETNLVALPSPDLLETPSKSRQDDPLMGCLAAIRALSLQDDAAIGKPPTPQPPSQDDPPYARQTAFARSRTSYETQTSTFFTAFFHALYAYTLSRISSSCIQVRPEEVPYTFGKGRGNRESGRRNGLFVACPDGAFYSTNNPSRKGSPFAFFELKPLPRASAQQRILREETAETVAILSHDLRGGKLRVRRAGDNPLPSSSLGHDEARPDLDKHHRLMISLDKDEFWLIHASFTDKYLTYITDMEQTTLPALHLGDDEFIEFRTYGPLRIGMRDELGCFCAIAIALALHQLKTSDIGRSLLLRLERGPELAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0W7</accession>
    <name>E3R0W7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Histone-like transcription factor and archaeal histone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_11905</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NFYC/HAP5 subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697510">
        <property type="protein sequence ID" value="EFQ36755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100775.1">
        <property type="nucleotide sequence ID" value="XM_008102584.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0W7"/>
    <dbReference type="STRING" id="645133.E3R0W7"/>
    <dbReference type="GeneID" id="24417268"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11905"/>
    <dbReference type="eggNOG" id="KOG1657">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045277_1_0_1"/>
    <dbReference type="OrthoDB" id="1272441at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016602">
        <property type="term" value="C:CCAAT-binding factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903715">
        <property type="term" value="P:regulation of aerobic respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd22908">
        <property type="entry name" value="HFD_NFYC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000017">
        <property type="entry name" value="Ccaat-binding factor complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050568">
        <property type="entry name" value="Transcr_DNA_Rep_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252">
        <property type="entry name" value="HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252:SF8">
        <property type="entry name" value="NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0010">Activator</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="9">
        <location>
            <begin position="78"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="168"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="264"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="174"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ36755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="283" mass="30945" checksum="48D7097E4ABA3A7C" modified="2011-01-11" version="1">MDPQNQSGSHAQQGRPQPVYDTTHGGHYGASAALSAQGFAPAELYTGPWANVHQGLTGQYKDILTTYWQQTINHLESDNHDYKLHQLPLARIKKVMKADPEVKMISAEAPILFAKGCDIFITELTMRAWIHAEENKRRTLQRSDIASALAKSDMFDFLIDIVPREEASSHAKRTTGQAAPTPQGVPAQTNSQMPGQHGSLQQGANHSSSSHPMAATDYGLAGHALGPDQDYRQNPNMYPGQVQPGPSAAYGQAQQPMYGEIEGMYGYGGMQPQQPPMSTEEFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>E3R160</accession>
    <name>E3R160_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11993</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697648">
        <property type="protein sequence ID" value="EFQ36848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100868.1">
        <property type="nucleotide sequence ID" value="XM_008102677.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R160"/>
    <dbReference type="GeneID" id="24417356"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11993"/>
    <dbReference type="eggNOG" id="ENOG502RNYI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1434352_0_0_1"/>
    <dbReference type="OrthoDB" id="10378142at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180142" evidence="1">
        <location>
            <begin position="20"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="189" mass="19773" checksum="76EDB8C28FC6A6A8" modified="2011-01-11" version="1">MHHSATFAAVVSLATGSLAAVAGRQLVPRDDCGGLTNVPLSPDPAHSSYTFTLDPTVKDVIANFAKSSGTTFNTIVVDQYCYESNNWGWANITQFGPGAEYTITTDKCEDGNSRSPLSYSVSLCVGDGTECNSTNPWAVCGAPGASDNFRPFCAVTEPLGGNPKAVALNDTTAWSCQVCPGSSNTCVWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q258</accession>
    <name>E3Q258_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_00303</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089179.1">
        <property type="nucleotide sequence ID" value="XM_008090988.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q258"/>
    <dbReference type="STRING" id="645133.E3Q258"/>
    <dbReference type="GeneID" id="24405668"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00303"/>
    <dbReference type="eggNOG" id="ENOG502SSR5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078005_0_0_1"/>
    <dbReference type="OrthoDB" id="3800738at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ25159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="338" mass="38462" checksum="7A05B1510C59E80B" modified="2011-01-11" version="1">MPESRTGDAMEAVLAIPELLEAILVQVDMRTLLVSVSRVSRTWKAFVDGSPALQQALFFKPVSDASRGTIHGLEGIPFPRVPIEYRLLSDNDARLINPLLAEKFDKCFFDFGPTCSFHRRLNSFYELPWSIRPEPVQTIRENWGGWTQVRPAELDEESARALAESRRRFTRRGASWRWMLVSQPPPPSLGYMRFDVRSITASDQVVSSSWIRPGGETAIAGFRMGELYDVVLHGSGYHGRQSLWFRVLWGRPTSGFALPHAKGVFEKLTSQTGVVVEFMQAGDWALPSNPRNPADVRVFDAAFRCEEYSEVGFETEETGAEEDCYPDYHPENMIWHWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2J5</accession>
    <name>E3Q2J5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Protein phosphatase 2C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_00440</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the PP2C family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089316.1">
        <property type="nucleotide sequence ID" value="XM_008091125.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2J5"/>
    <dbReference type="STRING" id="645133.E3Q2J5"/>
    <dbReference type="GeneID" id="24405805"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00440"/>
    <dbReference type="eggNOG" id="KOG0698">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013173_9_1_1"/>
    <dbReference type="OrthoDB" id="10264738at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.40.10:FF:000078">
        <property type="entry name" value="Protein phosphatase 2C, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF837">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C-LIKE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="7">
        <location>
            <begin position="139"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="90"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="298"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="481"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="15"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="31"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="50"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="90"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="298"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="498"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="547"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="562"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ25296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="591" mass="62710" checksum="1C013F268299B6FC" modified="2011-01-11" version="1">MFGGGSSSAASKAQSDLKEDRKSPSPESDKGSTAATKSSDQAASGDKRSGNSSPPGRQQQDGAVDKKRRASGVQSKAAGLLAHAKNTLNFSQVGRNSSDASSQTPLQKLGKQDPALAVPQGQHNNSAGDSIPGPRSTFRVGVWEDRNKKCRRTMEDTHAFLYNFLHTPAPVLDGKKNNSAADDKEALAQDMVETDNGYFAIFDGHAGTFAADWCGKKLHIILEDIIRKNPNGPIPELLDQTFTSVDAQLEKLPLKNSGCTAAVAVLRWEDRVPSDRSATGSQAIAPATAAATKAAKLSTEEIKDDKTTSASGTEAAHAKLKSSASRQRVLYTANVGDARIILCRAGKALRLSYDHKGSDENEGKRIANAGGLILNNRVNGVLAVTRALGDTYMKDLVTGHPYTTETVIQPESDEFIIIACDGLWDVCSDQDAVDLVRSVEDPVEASKLLVDHALNRFSTDNLSCMIVRLDKEALLESQNDKENAIGVERPPTNSAKVSESEKIIRETKQKIAEGGAPAVGVSASNSGRGHDPASIDNGDFKPTTLDDTLEEEPGPMDDGDSPEAAPDVVPALLPAEVEQTDTAASKKSSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2R2</accession>
    <name>E3Q2R2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cwf15/Cwc15 cell cycle control protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_00035</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in pre-mRNA splicing.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWC15 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ24891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008088911.1">
        <property type="nucleotide sequence ID" value="XM_008090720.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2R2"/>
    <dbReference type="STRING" id="645133.E3Q2R2"/>
    <dbReference type="GeneID" id="24405400"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00035"/>
    <dbReference type="eggNOG" id="KOG3228">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068312_0_1_1"/>
    <dbReference type="OrthoDB" id="30179at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006973">
        <property type="entry name" value="Cwf_Cwc_15"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12718">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN CWF15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12718:SF2">
        <property type="entry name" value="SPLICEOSOME-ASSOCIATED PROTEIN CWC15 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04889">
        <property type="entry name" value="Cwf_Cwc_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="63"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="119"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="143"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ24891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="237" mass="27066" checksum="A66D33E10A9EBA42" modified="2011-01-11" version="1">MTTAHRPTFDPARGKEALRGPAYHQRLLPAHTQLKFRQAGQGGDADDEARDLRAELLAAEAAHFAKKNGGAPPPSANDDTDAPAGGVKRALEAGSQADGEEDFEAKRRRILEESRDIDASSDEEEEEDDDDDSDDDSDDEEAELQREMEKIRRERAEKREREERERAKAEEEARERDIALGNPLLNKPDFNMKRRWDDDVVFKNQARGTEEKGKSKEFINDLLRSDFHKRFMSKYVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q337</accession>
    <name>E3Q337_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">GLRG_00160</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089036.1">
        <property type="nucleotide sequence ID" value="XM_008090845.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q337"/>
    <dbReference type="STRING" id="645133.E3Q337"/>
    <dbReference type="GeneID" id="24405525"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00160"/>
    <dbReference type="eggNOG" id="KOG0578">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_26_2_1"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010629">
        <property type="term" value="P:negative regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000910">
        <property type="term" value="P:negative regulation of sterol import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019236">
        <property type="term" value="P:response to pheromone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035376">
        <property type="term" value="P:sterol import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01093">
        <property type="entry name" value="CRIB_PAK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06614">
        <property type="entry name" value="STKc_PAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000139">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000356">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000535">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.810.10:FF:000005">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.810.10">
        <property type="entry name" value="CRIB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000095">
        <property type="entry name" value="CRIB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036936">
        <property type="entry name" value="CRIB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051931">
        <property type="entry name" value="PAK3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033923">
        <property type="entry name" value="PAK_BD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45832">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45832:SF22">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE SAMKA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00786">
        <property type="entry name" value="PBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00285">
        <property type="entry name" value="PBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50108">
        <property type="entry name" value="CRIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0589">Pheromone response</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PH" evidence="12">
        <location>
            <begin position="81"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="CRIB" evidence="14">
        <location>
            <begin position="194"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="565"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="259"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="367"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="298"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="309"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="468"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="517"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EFQ25016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="854" mass="93881" checksum="1DA05A8EC107C1F5" modified="2011-01-11" version="1">MANERSVYSSGQFMNPGPAPRPPADRPRLALTPNNSLPGNMANMAISPIRSTATSTYTGSTISLPIARQQSGQNDGMGGVAVKKEGWASVKESKNFINPWKQKYLILRKESLDFHKTEGGKVTYTLYLKDVVNVGRVEAAGTIFEIKRNPNGSSNSPGEDDGQTKTLQIRVKSDDDLYEWIDLIYGACPGMGGVSNPTNFSHAVHVGFDPQTGEFVGLPPEWSKLLNSSAITKEDYERNPQAVFEVLDFYSDLTKRAENPQQYSSLTPTPPASSQQNKQLGYGGGGSSVAPPRPMPPSQAQRQPSYNTQPSSQGQQRRPSPTEQQQQQRLQMQGMASNYQADPREEQRLKQLEAQRIREREIEEQNRRDLEAFNASIPKTKTPMAQQEIGGFGGGSSIPPTDRYNPSRAAPPAPKPSQQQQANGLRAQRPAPSPPTAGTSNRPPMASQQSSSSMRDPNQAQRAPRPDQSSSQQQRYPNGSPQQPRQPQAQAAPPSRLPAPVKPLNVSKAQPVPQTDAVKAAEAALTAKPPAQDRKQDVRMSTMSESEVMAKLKEAVSKDDPNLSYSKQKKIGQGASGSVYVAKVKEGAVSPIARDVLRAQGIKAQVAIKQMDLAHQPRKELIVNEIMVMKDSRHRNIVNFLDAFLRNNNAELWVVMEYMEGGALTDVIDNNPSITEEQISTICLETCSGLQHLHSQNIIHRDIKSDNVLLDARGNVKITDFGFCAKLTESKSKRATMVGTPYWMAPEVVKQKEYGPKVDIWSLGIMAIEMIESEPPYLNEEPLKALYLIATNGTPRLKKPEKLSKELKAFLSVCLCVDVKSRASADELLQHDFLKHGCPLGSLAELLAFKKHAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q380</accession>
    <name>E3Q380_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Zeta toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_00203</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089079.1">
        <property type="nucleotide sequence ID" value="XM_008090888.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q380"/>
    <dbReference type="GeneID" id="24405568"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00203"/>
    <dbReference type="eggNOG" id="ENOG502RKKK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043074_1_0_1"/>
    <dbReference type="OrthoDB" id="2881954at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010488">
        <property type="entry name" value="Zeta_toxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06414">
        <property type="entry name" value="Zeta_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zeta toxin" evidence="3">
        <location>
            <begin position="35"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ25059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="318" mass="35016" checksum="807F75B2D86D5E38" modified="2011-01-11" version="1">MPPPPDLSHYILSDSESREIFATKILPIDITQSLTPHPTRSRPLAVLIVGQTGAGKTRTAPTVLDAMTRIHPPVHLIADVYKAYHPSYLSLLDSATPAYASPATGPDARKWLAMAAAEAVARKLDVLLESACRHPDDFCELARLFGEAGYRVEVVVMAVPAALSRLGILHRFYERLPEAGSGRLPIRLTPVKVHDDSYEGLMSVAEWIDGVDYVDRVLIVRRGNMVAFSDEKAEDGKLQGKVAEGVRRERDRPLTEEERGVAVRDLEKLAARDTSLAAQIMELLEPLLRDDDHTYPGLRPLVFPPDGPKEALLTLGKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3A0</accession>
    <name>E3Q3A0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00646</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089522.1">
        <property type="nucleotide sequence ID" value="XM_008091331.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3A0"/>
    <dbReference type="GeneID" id="24406011"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00646"/>
    <dbReference type="HOGENOM" id="CLU_2446590_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="90" mass="9886" checksum="37D0C3494ADB016E" modified="2011-01-11" version="1" fragment="single">STSYSYVLSSNCPSILQDRSKKEKKKKTPPSGHPPLATAQFSMLPIISHVRSCITNPKPLPCQRAGLRQISSVKKNKSKRSKKISSSNCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3B3</accession>
    <name>E3Q3B3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00659</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MIP18 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089535.1">
        <property type="nucleotide sequence ID" value="XM_008091344.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3B3"/>
    <dbReference type="STRING" id="645133.E3Q3B3"/>
    <dbReference type="GeneID" id="24406024"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00659"/>
    <dbReference type="eggNOG" id="KOG3381">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075876_1_0_1"/>
    <dbReference type="OrthoDB" id="2746at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097361">
        <property type="term" value="C:cytosolic [4Fe-4S] assembly targeting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="entry name" value="Fe-S cluster assembly (FSCA)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039796">
        <property type="entry name" value="MIP18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12377:SF0">
        <property type="entry name" value="CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12377">
        <property type="entry name" value="CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="Fe-S cluster assembly (FSCA) domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ25515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="205" mass="22847" checksum="55DC7FDD40A29264" modified="2011-01-11" version="1">MDKDLDNANPTILSAAQLPTRQNKRTAPKTGPEHMFDDIIYAKPWYLSQPFCDDESLWSDADTELDKWAPEPIDEQEIYDLISTISDPEHPLSLGQLAVVNLPDIHISPPPQAGAMDPNRLVRVLVELTPTVSHCSLATVLGLGVRVRLEKALPPNWRVDVRVKENAHAQDDQVNKQLSDKERVAAALENDTLKGVLDKMLETCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4K4</accession>
    <name>E3Q4K4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Esterase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_01163</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ26019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090039.1">
        <property type="nucleotide sequence ID" value="XM_008091848.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4K4"/>
    <dbReference type="STRING" id="645133.E3Q4K4"/>
    <dbReference type="GeneID" id="24406528"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01163"/>
    <dbReference type="eggNOG" id="ENOG502S8NC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058064_0_0_1"/>
    <dbReference type="OrthoDB" id="3363286at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="331"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="398" mass="45287" checksum="D91C040B77A5D767" modified="2011-01-11" version="1">MQCVGVFARCEYGDGSEAEKMQKRQSAAGDALALSTPIRLCPITYVRLPKYFLQEFKAIENPETRSFWWTPGDLDVMYAAKEWERDDEPHEDDVPSGPQNSTDTPVAQQKATEKLLKQSPACYVLARRPFLKSMSGTKKKAPHGEKWRTMLSRREGSLAQRIAKRQVWREDMDDFVLDNMRRNVMKYLVYFAELRAGQDHRSYLLRLGSWDRAATIPQRGCLLWYYAENGPKRQGAAVGPDGGDNAAAAVATALEPFSTYDVPKAKYERKLPVYDLRWLLGEDHLAKLREIPMFRDSSLFLLRKQRSIPLQLYLWKLQAYMAEYDAPEVTHVPESESAGGQPSSTDEKQPRGLSHENDAATLALPEREGRKDSRELEHTRKPTSSGLADSSRKDPKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q595</accession>
    <name>E3Q595_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">CFEM domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_01006</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089882.1">
        <property type="nucleotide sequence ID" value="XM_008091691.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q595"/>
    <dbReference type="STRING" id="645133.E3Q595"/>
    <dbReference type="GeneID" id="24406371"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01006"/>
    <dbReference type="eggNOG" id="ENOG502SZ7B">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063084_5_1_1"/>
    <dbReference type="OrthoDB" id="3767534at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00747">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="9" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179423" evidence="10">
        <location>
            <begin position="17"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="11">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ25862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="176" mass="16258" checksum="5166E54BB50F0790" modified="2011-01-11" version="1">MKYSFALASLIAVAAAQSGSSPIPECAQKCLADATSSATSCKLGDYACTCEPANKAAISAAASSCVLAACGADTALNQVLPASDKLCAEAAAGGGAASSAPAAASSAAAATSAAASSASYHSSAAASHAATTATSHAAATSTANATATTTTPVQAGAAGVAPFGGLAMLLLGALAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5I8</accession>
    <name>E3Q5I8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_01099</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089975.1">
        <property type="nucleotide sequence ID" value="XM_008091784.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3Q5I8"/>
    <dbReference type="GeneID" id="24406464"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01099"/>
    <dbReference type="eggNOG" id="KOG0519">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002763_0_0_1"/>
    <dbReference type="OrthoDB" id="303614at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009927">
        <property type="term" value="F:histidine phosphotransfer kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.130:FF:000023">
        <property type="entry name" value="Sensor histidine kinase/response regulator, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.40:FF:000083">
        <property type="entry name" value="Sensor histidine kinase/response regulator, putative (AFU_orthologue AFUA_4G00660)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047:SF72">
        <property type="entry name" value="OSMOSENSING HISTIDINE PROTEIN KINASE SLN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047">
        <property type="entry name" value="TWO-COMPONENT HISTIDINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="611"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="9">
        <location>
            <begin position="1170"/>
            <end position="1291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="270"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="502"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1055"/>
            <end position="1168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="301"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="326"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="342"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="502"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1084"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1109"/>
            <end position="1130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1137"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="1221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ25955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1304" mass="142093" checksum="8CC71144F7216AB8" modified="2011-01-11" version="1">MNKISEGAREWETFKCVTPTSKACSVRRSRYLVGSWTGLPYDLTVRLTNLGNKRYDSFHIPSAVFNSPDRPIPPSSLASSPDTGLTAFAQLGALRLNASRALISLFDRRNQYIVAEATRYMPLAPDAKYPKQNHLWLCGTAIPRAFGICEHVLVGATQDASNSRHPSAPANENELPVAVVPDLAADRRFCDRPYIEAAPFNRFYAGVPIQSPKGINIGVYCIFDDRPRAGLDADSVQFLRDTSHTIMNYLEARRVNESYRRSERMVQGLGNFIEGRDDPIPPPKFDPRSATNGFEPPQLAVSLSGTDSPSPDSPETAEPPVRPGINPTSPEATGSPTKIDSSDSVETTATTATVATTTSSTAPPDPHLSGTIKIFSRAANVIRKYLEVDGALFLDASIGSFGGLVTGPRRASEVADHDFSSSEDSLSERLEDDDDRWCKTFGRSSTLESGGSSSGPDMPQLGCKTLRERFLRKLLRKYPNGKVFSFDETGNWLAADYESDDADITPTEETEQQPTRPDSKAAHSYFTKRNEAKTIIDIFPGARSIAIVPLWDPSKEQCFAGGFVWSKSATRILTPAADLPFLRAFGMVTMSEVIRLDAILADRAKTDILGSLSHELRSPLHGVVAAAELLHDTQLDAFQVDVIHTIEISGKTLLDTIDHLLDYSKVNTFLRASKSRRQNSGMGRGLRPETSASIESGMMSLVSDVHLDLLVEEVIESVFIGHSFHHMVASSLARHGTSSGPSTPAQEKLDAIATSDGLGHRRGPSESQPASLKDVKILVDIDPQSSWVFHTNPGAIRRVVMNLFGNALKYTSKGFIKIHLRQEEVVHKSSRSASMVVLTVTDSGKGISEEFLHNKLFTPFSQEDSLAPGTGLGLSLVRQIVTGLGGTISVRSQVGHGTSMTVSMPLVLSRKANGRGRKFSSDLETLAGTRLSVRGFSRGLEDSEELRAGGLDLPVESLPFKWMDVKINEDSRSPDGSDLMVCSEEAFRRHGMSETGGVETPLVVVCGNAEAAQKLATSYRRSLRHEAVMEFIAQPTGPRKVAKALACALDRWKQRQPAARPIPVSPQSEAFPRLAPSPRALKSDTLTTRPRAQSETARMVRVTSPPPDNASQSPGDSWIANTNDSNNFTLTLPFRPAPSAATPAMSTAPAKGSTKTSVPPSPETAKSPSEFLLVDDNAINLKILSAYMKRLQKRHTTASNGLEALQAYTTQPQRFCCILIDITMPVMDGLEATRRIRKFERAQNLAPATVIAITSLGSQSARQEGFASGMDLFLTRPVTMKELVKILKLRKLVDEITEKEVLSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5U2</accession>
    <name>E3Q5U2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transmembrane protein 14C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_01334</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM14 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090210.1">
        <property type="nucleotide sequence ID" value="XM_008092019.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5U2"/>
    <dbReference type="GeneID" id="24406699"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01334"/>
    <dbReference type="eggNOG" id="KOG4267">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096652_3_0_1"/>
    <dbReference type="OrthoDB" id="5620at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1740">
        <property type="entry name" value="Transmembrane protein 14-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005349">
        <property type="entry name" value="TMEM14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044890">
        <property type="entry name" value="TMEM14_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12668">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 14, 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12668:SF15">
        <property type="entry name" value="UPF0136 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G03720)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03647">
        <property type="entry name" value="Tmemb_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ26190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="106" mass="11003" checksum="23D820E4496D8601" modified="2011-01-11" version="1">MSSDLSVTSFALGALTATGGIIGYARTRSVPSIVAGVSVGLLYGLGGYRIQNGEPYGVELSLLASAVLGGSAVPRAIRLRKPVPILLSVLSLFGLYSFGNEFRRTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q604</accession>
    <name>E3Q604_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sodium/calcium exchanger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_01396</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090272.1">
        <property type="nucleotide sequence ID" value="XM_008092081.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q604"/>
    <dbReference type="STRING" id="645133.E3Q604"/>
    <dbReference type="GeneID" id="24406761"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01396"/>
    <dbReference type="eggNOG" id="KOG2399">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004979_2_0_1"/>
    <dbReference type="OrthoDB" id="407410at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="entry name" value="NCX, central ion-binding region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051359">
        <property type="entry name" value="CaCA_antiporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12266:SF0">
        <property type="entry name" value="MITOCHONDRIAL SODIUM_CALCIUM EXCHANGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12266">
        <property type="entry name" value="NA+/CA2+ K+ INDEPENDENT EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="202"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="226"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="584"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="616"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="755"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="786"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="819"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="843"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="885"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="932"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="969"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="9">
        <location>
            <begin position="107"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="9">
        <location>
            <begin position="823"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="430"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ26252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1002" mass="109990" checksum="810885A8B31577B6" modified="2011-01-11" version="1">MPADSKLRGSGLRLRPFYATVFLISLLALWSLLSKTTERQLRLQDTSPLTKRSELTACRDVHRANDQCAFVKAHCADDEPGLISYLTLYYCGLAKVQSLAFVILVCWLGLLFTTIGIAASDFFSVNLNTISAILGLSESLAGVTFLAFGNGSPDVFSTFAAMSSNSASMAVGELIGAASFITAVVAGSMALVREFKVGRKTYVRDLSFFIVAVCFTMLFLADGHLHLWECITMICYYMFYVVTVVTWHWYSTRRSQQRAREAAARGHVYGAVGHLSDELAPEPYRDDPDEEDRRVMSVAASSTRDINMLEAGPRIEVDGHAEEQDEVEDSDHGRHVVAEMASSMRVLRPRGRRRNTLTPIRPSLVGALEFRSTLAQLQKESNHRMRPMHGRAHSVNHLGGVSETNTILGPPSDSGRYTIGAVEEFGQNRNRALSSGDVPGSVTSRDPSPWRFPPSAAHANPIQQVKAQDARNRSRSPAFKIGGNLAPPPVDMVPPQRQDSGGSDAIEPRPSSGVLLSLQIPSRRGSFSDRSSPVSPFPGYTESPLALTPAAQNEQADYFTSPGVTRLEVPFAPYEMAAPKPVKWWPYAILPPPHILWATLFPTLLGWKQKSHWDRFVSAISVPSILLLVVTLPVVENESADDALDETAADPLMREHDHCDVMLPAAAYYGIGEETEWQRFRRSTMSHSRVHSVHSIDQSPKDYSPKASPALIAIDTPNGARVSAEIHPQHTKKATMLPSESSLAAADDSGHWNRWLVVIQLFTGPLFAVIILWANMKEDFDQPYKTLVRFVLYTLMASTALLGFLLLATSPDKRPKYHFLLCFMGFIIAIAWISTIASEVVGVLKAFGVIFGISEALLGLTIFAAGNSVGDLVADITVARLGFPVMALSACFGGPMLNILLGIGIGGVYMMVQAANHRHNKHPDRPLKYHSYEIQIGGTLMISAITLLLTLLALLIIVPMNKWVMSRKIGYGLIVLWTVSTIVNVAVELTGVWTDVSYFLTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q623</accession>
    <name>E3Q623_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fibroin-3 related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_01415</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090291.1">
        <property type="nucleotide sequence ID" value="XM_008092100.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q623"/>
    <dbReference type="STRING" id="645133.E3Q623"/>
    <dbReference type="GeneID" id="24406780"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01415"/>
    <dbReference type="eggNOG" id="ENOG502SAKR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022094_0_0_1"/>
    <dbReference type="OrthoDB" id="5401332at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005935">
        <property type="term" value="C:cellular bud neck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037504">
        <property type="entry name" value="PSI_induc_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40018">
        <property type="entry name" value="[PSI+] INDUCTION PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40018:SF1">
        <property type="entry name" value="[PSI+] INDUCTION PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="473"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ26271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="547" mass="57601" checksum="39802E30A44B214D" modified="2011-01-11" version="1">MPSIDVAMARSLRGGVLGSVVSSLAANIESRGITDTVTNAGNQISDVKKAFSSWDNCMAVTYCKWPVIGVIIVISLIVFSVVWCIIRCACCGLSCCCQCCYCLKCCGECCGCCDTPKGTPHKHLDDSYGPTNQGYKSQAPMAPFYNGAPAHATHSTAPAATATTATTASGAAAPPQYAEFEVSKSGSNPADADSLPAMPSWEGAGSKKVAVEEEVELEQMKPAASPNPNGQNMPLLAPNATSHPNSPMPGDRSPYGQNAQAGASGYFPDTNQPANSYAMGGQGPNGYNGAYGQSTSSFGVDQGYGAGAGGMAVAGGMAMAQGGRPPHREFNNGGYGQQRGQTYPPPQQEFDQGYSNYEQGGYGMGRPPRNGPSPAPIPRSFTAPLRNGPSPAPPGFRRSPGPPSDYRGSPAPPNDYRRSPAPPSEYRRSPAPQNDYVYDQKDQYPGDNYGRPQYGGGARQYSSESTRPLAPQRSYTTESVSPNLQNTAGFDFSGNSRPQQYNYNRGPGGGAPQHVEEEEEQRPPQSSGGTYPGYKAYQPTKDGWSGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6P0</accession>
    <name>E3Q6P0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Golgi SNAP receptor complex member 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_01632</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of several multiprotein Golgi SNARE complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the GOSR1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090508.1">
        <property type="nucleotide sequence ID" value="XM_008092317.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6P0"/>
    <dbReference type="STRING" id="645133.E3Q6P0"/>
    <dbReference type="GeneID" id="24406997"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01632"/>
    <dbReference type="eggNOG" id="KOG3208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078034_1_0_1"/>
    <dbReference type="OrthoDB" id="422156at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005801">
        <property type="term" value="C:cis-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005797">
        <property type="term" value="C:Golgi medial cisterna"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048219">
        <property type="term" value="P:inter-Golgi cisterna vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023601">
        <property type="entry name" value="Golgi_SNAP_su1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21094:SF2">
        <property type="entry name" value="GOLGI SNAP RECEPTOR COMPLEX MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21094">
        <property type="entry name" value="GOS-28 SNARE- RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12352">
        <property type="entry name" value="V-SNARE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF027109">
        <property type="entry name" value="Golgi_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="7 9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="210"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="48"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR027109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ26488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="228" mass="25989" checksum="A4BF0F4D48D305AF" modified="2011-01-11" version="1">MAAASVNTGWTQLRQQARSLETQTETLFHTYSQFSTVADIPARPTEEERTTEAKLQELLEKRENVISQLYRLLDSEATLTSSATKHSNLALSREKLAEHKRDLVRLRNTIAQARDRAHLLTNVRSDIDEYRANNPEAAEAEYMLAERSRIDNSHNMTDSVLAQAYAVQDSFNIQRETLASINRRITMAASQVPGLNSLIGRISAKKRRDGIIMGVFIAFCFLLFWWFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6Q4</accession>
    <name>E3Q6Q4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">COP9 signalosome complex subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_01646</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CSN4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090522.1">
        <property type="nucleotide sequence ID" value="XM_008092331.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6Q4"/>
    <dbReference type="STRING" id="645133.E3Q6Q4"/>
    <dbReference type="GeneID" id="24407011"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01646"/>
    <dbReference type="eggNOG" id="KOG1497">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028132_1_1_1"/>
    <dbReference type="OrthoDB" id="295656at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008180">
        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054559">
        <property type="entry name" value="PSMD12-CSN4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040134">
        <property type="entry name" value="PSMD12/CSN4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10855">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10855:SF2">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22241">
        <property type="entry name" value="PSMD12-CSN4_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0736">Signalosome</keyword>
    <feature type="domain" description="PCI" evidence="8">
        <location>
            <begin position="202"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ26502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="421" mass="45992" checksum="A366A025C4B8562B" modified="2011-01-11" version="1">MAPSLKVAEALAQAESVPRDKTAAYESIIADIKTLSSPATAADDLAAVLDAAFAASLGIVSTRAVLASFVATLRDLKNDDLWIAVGNYTLSQLAAGAQASSFLDQAAAVRELVAEAQENNEDFLDAAKTLAEIPLDGSQRKVTNDDKARVWVRIARNYLEVDDTTAAETYVNKLKNIMHTVQDRDLDLHFKLSQARILDSKRDFLGASGRYHEISVSPAIAEEERLHTLSMAVKCAILAPAGPMRSRALGRLYKDERSAGLDEYGMLEKMFFDRLLAPAEVEKFAQGLQPHQLATTADGSTVLAKAVVEHNLLGASRLYRNIGFEALGSLLGLDRERAEETTARMIEQGRLLGRIDQLEEIIWFEGGEASGKKGSGRAEVVVGKEMRRWDSNVQNMAEEVENVTSALQKQFPDFVENNLVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6S0</accession>
    <name>E3Q6S0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_01662</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090538.1">
        <property type="nucleotide sequence ID" value="XM_008092347.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6S0"/>
    <dbReference type="STRING" id="645133.E3Q6S0"/>
    <dbReference type="GeneID" id="24407027"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01662"/>
    <dbReference type="eggNOG" id="KOG2614">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014528_0_0_1"/>
    <dbReference type="OrthoDB" id="1047367at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.400.10">
        <property type="entry name" value="Acetoacetate decarboxylase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010451">
        <property type="entry name" value="Acetoacetate_decarboxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023375">
        <property type="entry name" value="ADC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF261">
        <property type="entry name" value="HYDROXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G00590)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06314">
        <property type="entry name" value="ADC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160104">
        <property type="entry name" value="Acetoacetate decarboxylase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="27"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ26518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="714" mass="79256" checksum="49AC75E5396C2C08" modified="2011-01-11" version="1">MLINGETQHPNGAHSSPMTHDRPRPLKVAIVGAGIGGLSAAIALRREGHQVDLYEQSRLANEIGAAVHLAPNSNGLLRRWGIYAETFGANPAHRFKERNLHNKGGLDVDITKSEGQWQHPWQFVHRGLLHSELRNVATAEDGVTPPAKIHVASKVVSANPEKGEIQLENGTTVQADVILGADGIYSRVRKYITGTDYKLFRSGKAAFRFLIPTAAALEDPVTAPLIEKENCLSIWFGTDRRIVVYPCNNNQLLNFVCIHPDTESHATTTDGWSKKGSMEQLLKVYNEFDPDVLQLLKKVHPDEVNVWQLLDMEAMPTWVNDKLALLGDAAHPFTPHQGQGAGQAMEDAAALAVVLPKGTYPEDVTERLRLYEQIRLERAHKIQEFSRQAGMDRIPGQQLPPINMMEYTNYNFGHDAHDHATKMFNKYLWSKKKDLYWRMPVGFGPFPGPRQDFYGRRQPSELDRTFKTISVKFLTSRTLLETILPNDSFRFKAPGTVCTASLSTTQLNNMSWLGGGGYNHLGLYIHGIEYVKRDGTSVDGTHLAVLFESLADPIVSGREELGMPKLFCDIDVEHHATAARVRASWRSTRFIDISLDNLRKDDPETEHGTIGGEADYGILTYRYIPSVGNPGKADAAYACVVPHEEEARDVPSTVHAVARSPSASVTVEGHDWEKLPTLHHIAKVLAEMPIYKVLGAKVVEGTGVPNVSAARRIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q716</accession>
    <name>E3Q716_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phytoene desaturase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Carotenoid biosynthesis cluster protein B</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Phytoene desaturase (3,4-didehydrolycopene-forming)</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">GLRG_02474</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>15-cis-phytoene + A = all-trans-phytofluene + AH2</text>
            <dbReference type="Rhea" id="RHEA:30603"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:27787"/>
            <dbReference type="ChEBI" id="CHEBI:28129"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:30604"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>all-trans-neurosporene + A = all-trans-lycopene + AH2</text>
            <dbReference type="Rhea" id="RHEA:30623"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15948"/>
            <dbReference type="ChEBI" id="CHEBI:16833"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:30624"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>all-trans-phytofluene + A = all-trans-zeta-carotene + AH2</text>
            <dbReference type="Rhea" id="RHEA:30607"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:28068"/>
            <dbReference type="ChEBI" id="CHEBI:28129"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:30608"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>all-trans-zeta-carotene + A = all-trans-neurosporene + AH2</text>
            <dbReference type="Rhea" id="RHEA:30611"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:16833"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:28068"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:30612"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 14">Carotenoid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the carotenoid/retinoid oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090674.1">
        <property type="nucleotide sequence ID" value="XM_008092483.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q716"/>
    <dbReference type="STRING" id="645133.E3Q716"/>
    <dbReference type="GeneID" id="24407839"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02474"/>
    <dbReference type="eggNOG" id="KOG4254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019722_2_1_1"/>
    <dbReference type="OrthoDB" id="7777654at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016166">
        <property type="term" value="F:phytoene dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016117">
        <property type="term" value="P:carotenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000171">
        <property type="entry name" value="zeta-carotene-forming phytoene desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014105">
        <property type="entry name" value="Carotenoid/retinoid_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02734">
        <property type="entry name" value="crtI_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43734">
        <property type="entry name" value="PHYTOENE DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43734:SF1">
        <property type="entry name" value="PHYTOENE DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 14" id="KW-0125">Carotenoid biosynthesis</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="552"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="domain" description="Amine oxidase" evidence="16">
        <location>
            <begin position="20"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00051356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00051545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00051928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00052475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00078033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU362075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EFQ26654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="577" mass="64387" checksum="F1AC7EEB5A89B9CF" modified="2011-01-11" version="1">MSQIGEKPKTAIVIGAGAGGVALAARLAKAGFAVTVLEKNSFTGGRCSLMFQDGHRFDQGPSLFLLPQLFHETFKDLGTTLADAGVDLLRCETNYNIWFHDGELFRHSSDLAAMKTQIERWEGKDGFERYLKWLREAHTHYEISVKDVLHRNFSKFMDLARPGFVRHVVNLHPLESIWSRASRYFWTERLRRVFTFAVMYMGMSPFDAPATYSLLQYTEFAEGIWYPKGGFHQVVAALVRIGEQMGVNYRLSTPVSRVLTDGKRATGVELESGESLSADVVVVNADLVYAYGNLLPKTPTITDYTKSLRKREASCSSISFYWCMDRKIPELSVHNIFLAEEYRESFDAIFKRHSLPDQPSFYVNVPSRVDTSAAPEGKDTVIVLVPVGHLAESKGESGLTTDPKHWDDIVARARAAVIEIVSARTGCAPLSDFITHETVNTPLTWEDKFNLDKGAILGLTHGIFNVLAFRPRTRAEGLEDAYFVGASTHPGTGVPIVMAGAKITAEQILDDRGLQVPWARGFDGILKPQSQSPGNKKLDSVRYGYHFGSEEVAVLSVGLVLALIYFYFWPTMQPFLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7J1</accession>
    <name>E3Q7J1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Ankyrin repeat and zinc finger domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_02649</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11">The VLRF1 domain mediates binding to the 60S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the ANKZF1/VMS1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090849.1">
        <property type="nucleotide sequence ID" value="XM_008092658.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7J1"/>
    <dbReference type="STRING" id="645133.E3Q7J1"/>
    <dbReference type="GeneID" id="24408014"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02649"/>
    <dbReference type="eggNOG" id="KOG2505">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014293_1_1_1"/>
    <dbReference type="OrthoDB" id="429841at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047139">
        <property type="entry name" value="ANKZ1/VMS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041175">
        <property type="entry name" value="VLRF1/Vms1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16036">
        <property type="entry name" value="ANKYRIN REPEAT AND ZINC FINGER DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16036:SF2">
        <property type="entry name" value="TRNA ENDONUCLEASE ANKZF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13857">
        <property type="entry name" value="Ank_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18826">
        <property type="entry name" value="bVLRF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52044">
        <property type="entry name" value="VLRF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 11" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11" id="KW-0540">Nuclease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="VLRF1" evidence="13">
        <location>
            <begin position="234"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="10">
        <location>
            <begin position="474"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="106"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="281"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="399"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="548"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="115"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="289"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="399"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="551"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="605"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS52044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ26829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="644" mass="71663" checksum="3ABE833943DF3D40" modified="2011-01-11" version="1">MDTKTTPDLLKRPLYVYDLPPEVLTTLSLKSDASIPDQTPPSPPAKDFSSSDLVDSQACSLCATTFSSVLDQRSHQKSDWHHYNLKQKLRGANPVSENEFEKLIGDLDESLSGSDSEESEDDEDEAGRKETTLTALLRKQATLAETNRTSVPGEEDEAEETVRRAGKGKPPLIWFTSPVLPPNTYFGLYRAILTGEELREDANLVEIVKKKQLDPIAAPKVPKDGSAPPPAAYKGPHFFLCMIGGGHFAAMVVSLAPRQNKSSVGALNREATVLAHKTFHRYTTRRKQGGSQSANDNSKGNAHSAGSSLRRYNEQALVEDVRNLLQEWKGLLDTSELLFIRATGATNRRTLFGPYDGQVLKHNDTRIRGFPFSTRRATQNELMRSFIELTRLKVREINPEDEAKPKAERLTPAKAAAPKPTKPKLTEEEETALLHTSQIQALIRRSKLPALLSYLKSNDISPDFQFQPPGQNYHAPTPLHLAAHQNAAPLVLGLITRAGASPLITNKDGKTPFDLAGDRSTRDAFRVARSELGEGKWDWDAARVPAPLSKAEAEKRDERDKKERESKETERRRAEEERLRAEGPRVDDRKKRAGALAAVASTKTAQEKREEEARGLTPEMRMKLDRERRARAAEERLKRMQGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7K7</accession>
    <name>E3Q7K7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcription factor SPT8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_02665</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090865.1">
        <property type="nucleotide sequence ID" value="XM_008092674.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7K7"/>
    <dbReference type="STRING" id="645133.E3Q7K7"/>
    <dbReference type="GeneID" id="24408030"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02665"/>
    <dbReference type="eggNOG" id="ENOG502QS8F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010934_1_0_1"/>
    <dbReference type="OrthoDB" id="10260946at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1900237">
        <property type="term" value="P:positive regulation of induction of conjugation with cellular fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057544">
        <property type="entry name" value="Beta-prop_SPT8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF8">
        <property type="entry name" value="F-BOX AND WD REPEAT DOMAIN CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23798">
        <property type="entry name" value="Beta-prop_SPT8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Transcription factor spt8 beta-propeller" evidence="5">
        <location>
            <begin position="88"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="218"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription factor spt8 beta-propeller" evidence="5">
        <location>
            <begin position="492"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="295"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="34"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="51"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="305"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="395"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="421"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ26845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="666" mass="70875" checksum="4B58A936AB8F20A6" modified="2011-01-11" version="1">MEDVDDADGDMENDDDDNDDEQDDNDREETGDDAQEKGDEAAARDAREPSRAGSAAARASPEGKGKSPMPFSSLFPTVRPEAVRARLYDIVPTMAAPQATSINAIAITPDLRYWMTGGSDGYIRKYDGPGTINGKQLLTVAQRHPFVDSVVKAGILMSYWENEEPGPPNPRGNEEHVLSPVYSLAVHSQALWLLSGLESGGINLQSVRHDEGKRITCLQQHTNAVSVLTLAQDEKSVLSGSWDKNIYDWDLHTGGVKRSFDGSGGQISAIELRPVNGAPIPAEAREEDIKFDATFTSNNNKPLQNGAADAANGADALASATSGEVAEGQASPAHESLFGGSDTGSLFGDNVAANYGGDDDDEFSRAMGDMGMPPLHDGSGQDGGMDHSADIDMTNAFNADSASAPAAQPRGSSSPEASKHLPPALAPDVAAPDRPSTQDGAKDTAVQLLASDIPEVPPVPDAQIDEPAPGSPSMVFASEPAVPAMDPTQSADTIFFSAAIDGTIRLWDRRVQDPVARISNQRGVPPWCMGACWSPDGNWIYAGRRNGTVEEYSIHKARSGWAPERTLKFPAGSGAVSAVRAMPNGRHLVCASHDILRLYDLKDTRAFKHSTVPFLIIPGPPRAGVISTLYIDRTCRFMLSAAGTRGWEGTSTEVLIGYEIGVTEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q878</accession>
    <name>E3Q878_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fic/DOC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_02261</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091110.1">
        <property type="nucleotide sequence ID" value="XM_008092919.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q878"/>
    <dbReference type="GeneID" id="24407626"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02261"/>
    <dbReference type="eggNOG" id="KOG3824">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066666_0_0_1"/>
    <dbReference type="OrthoDB" id="439046at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3290.10">
        <property type="entry name" value="Fido-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003812">
        <property type="entry name" value="Fido"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036597">
        <property type="entry name" value="Fido-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040198">
        <property type="entry name" value="Fido_containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13504:SF38">
        <property type="entry name" value="FIDO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13504">
        <property type="entry name" value="FIDO DOMAIN-CONTAINING PROTEIN DDB_G0283145"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02661">
        <property type="entry name" value="Fic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140931">
        <property type="entry name" value="Fic-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51459">
        <property type="entry name" value="FIDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fido" evidence="3">
        <location>
            <begin position="177"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="285"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="289"/>
            <end position="296"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ27090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="360" mass="40161" checksum="D1A7D6F57EF1257C" modified="2011-01-11" version="1">MSGKALLSKQRQARRALLTKIYEPALRLQRGSPEYAKLGSSGRIWEDYFRPGNSLEKGYVGLQQEHKRMLDKIDALKTSLPTAELSKTVVSEYAQQSVMIENNHLTVGDANRILESLQMGVFRRVDLASMPSSELVKIVTCKTEGGTDSATNELRNHIVASQWIAEGAAAKARTAGLREDEVRDLAVVCIRDTESEAAYEASRGGYQAGCPKAGTLVWGARVPLGEYRNLPIAVRSNRLRIFPYPQEVPACVARFFEWRDTQHREKTLHPLVLACQMTAYFVHVHPFPDGNGRTSRLIMQDYLARQGYLPVVIPGLERKDYLRMIDDACEGKPGELVAAVVEAQQAALHMFSTRCQEAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8K0</accession>
    <name>E3Q8K0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_02042</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ26871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090891.1">
        <property type="nucleotide sequence ID" value="XM_008092700.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8K0"/>
    <dbReference type="STRING" id="645133.E3Q8K0"/>
    <dbReference type="GeneID" id="24407407"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02042"/>
    <dbReference type="eggNOG" id="ENOG502QR47">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004835_2_2_1"/>
    <dbReference type="OrthoDB" id="4356994at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053181">
        <property type="entry name" value="EcdB-like_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="49"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="125"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="151"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ26871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="643" mass="71256" checksum="00AA2FDCF1DF5663" modified="2011-01-11" version="1">MDADRGFPDMGMPSGSPPGRLGVPVDHAHAQQADPRIPKQRTWSRASSACQTCRGRKTKCDNERPICGYCRRVGATCTYIEDSVPATSLCQGVGPRLLGAIENLANLIQRNEDNFRAIPQLSRDLSRDSADYPDSPTFQGGRPEPNILGQDSAAGGSTSLSLSDSAGLDSVLEWPIFPKPVPFAIDPFSHASPRAEVFSPRSPPAMEFYELSRLVDLFLANVNPMNPVIDGQVLRQMLKQVAENGPDWSAATCIVALTCALGAISQRPGQRTPSGTPRGYSVEPNRHLASRYWSVAEKRLGFSMGSPGWESVQCLCLAGIWHMYNMDPLQAWKCFSMASNTWYTTSLMNKLAKSSGKAETPSDFPQSLSLEQILYFTCFKSECELAFELSLPGSILAGVDYPYSLPNPSSPGVVNIDNKPLLMEHRSWHYYLAEISARHLINLIKQAQKRSPLNLTDAGIDRMLEVFDVYEAQLTDWYEQLPPPISFQVPAGEISPLADDLCQMLRSRYLAIRELLCRPFVRLATTISIPVTVSEHALTRVAEITSRGLQYCLYRIQATSSTPHHGLWLQLRGFVTCSLMLTAAERAQTIPSLNIPSRMAYPKNWKRTILVQKDILSNCWEFDEGGISDCARVLDWALAKFTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8L9</accession>
    <name>E3Q8L9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_02061</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ26890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090910.1">
        <property type="nucleotide sequence ID" value="XM_008092719.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8L9"/>
    <dbReference type="GeneID" id="24407426"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02061"/>
    <dbReference type="HOGENOM" id="CLU_2468934_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ26890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="88" mass="10269" checksum="C2A282FA0D6FB86B" modified="2011-01-11" version="1">MAILRCFRDDYIDYRKHIDRHIPLRNRQGIYTCPFRDAEAEGAPHWQPSRFLTIVIASATVEARYAQYCLHILPTMDCGLVATSLRRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8P7</accession>
    <name>E3Q8P7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_01906</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091431.1">
        <property type="nucleotide sequence ID" value="XM_008093240.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8P7"/>
    <dbReference type="STRING" id="645133.E3Q8P7"/>
    <dbReference type="GeneID" id="24407271"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01906"/>
    <dbReference type="eggNOG" id="ENOG502S2M7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016349_0_0_1"/>
    <dbReference type="OrthoDB" id="72851at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06421">
        <property type="entry name" value="CESA_CelA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050321">
        <property type="entry name" value="Glycosyltr_2/OpgH_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43867">
        <property type="entry name" value="CELLULOSE SYNTHASE CATALYTIC SUBUNIT A [UDP-FORMING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43867:SF2">
        <property type="entry name" value="CELLULOSE SYNTHASE CATALYTIC SUBUNIT A [UDP-FORMING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="207"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="506"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="536"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="610"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="637"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="9">
        <location>
            <begin position="258"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="97"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ27411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="662" mass="74557" checksum="F287717C9EB3101B" modified="2011-01-11" version="1">MSRPYTPRGTSPDSGLAPPANPFASNPFDTDNESSIAPTPNDSTSTVNAIPQSSLPGDSRTPYGADQRSSWADSSNHRLSRPDIPSPLAREVPVTNEKVNQQPSSDTDVEASHVPPVVSDPEKVNEKHTTALPASSGASFPKRLYNRFRATYCPKEEPPLVLPVCPNDTEKLSYVHTNRILLYVFGVFSFLSLGAGMWLFALSAPAFYWYGVFAGAMCIYLLISYAVGIIGRDWDYKAHLELVERFPITGDNAPTVDIFLPCCSEPVEILENTYKHIVNIDWPASKLQVHVMDDGASEPVRLLAQKYGFNYSVRDDRPRLRKAGNLRWTFAKTNGDFFAIFDADFCPRPDFLKELMVEHLGDDKTALVQSPQYFRVTDDQTWVEQGAGATQELFYRVVQVNRNRWGASICVGSNALYRRESLVEVGGTAEIGFSEDVHTGFGAVDRGWKVKYIPLCLATGVCPNSPRAFFSQQMRWARGSTTLLTNSHFWVSNLTLMQKICYLSGFMYYMAVSLNIFLAPIAGTLLLAIRPEWFKFWNLAFAIPSIAYGIILMRCWAKAKYGFNVQHAMTIMSYAYLTAIKDRLFNIELLWAASGDSKAHKSNKYRNMRILCIVWTIIVTGSMIGVVTWRIVTGFTWYHPLPLIIINVYNLFINHYFMFCDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8W0</accession>
    <name>E3Q8W0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fucose-specific lectin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_01969</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091494.1">
        <property type="nucleotide sequence ID" value="XM_008093303.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8W0"/>
    <dbReference type="STRING" id="645133.E3Q8W0"/>
    <dbReference type="GeneID" id="24407334"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01969"/>
    <dbReference type="eggNOG" id="ENOG502RQXA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027100_0_0_1"/>
    <dbReference type="OrthoDB" id="3800077at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.70">
        <property type="entry name" value="Fucose-specific lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89372">
        <property type="entry name" value="Fucose-specific lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ27474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="495" mass="53266" checksum="A4FC57494AC1D5B0" modified="2011-01-11" version="1">MSPVGAQNRGGERGTDTLPEVYEQPGLEAVPHEQDWSGLEVVSDHRHQDGNKEVIYRNNEDEKIPVVASEAEFDPAAQKSPPASAAARRMRKSWLMVGAGALLLIVAAVVGGVVGSKMAAGGAGRKDSPEAQPTPTPTSTANVTVANAREIRRGSSLAASGWWKNTGSEIFLFYQGDDNKIRRSVVDSTANNTSWQGPEELDSFATENSRLAGSTIVYDTGYVPQPELFYTNAQMQVLGISMNDLYTPTAQEDSIKTIGLRTIADSSVASYWPWSVHQAADGYIVEVRNRLIGGDFHPAAEWDAKRLRVQAVNASRLALVPTSTSFNRIAIQGGYGIFYQAANSSLVALIPDLANNVPADYVTSWPTDFPSITLPEHGTFAAFSVARPSDSLQRVDTYVLYLDASSDINVVYTDSSASSSPSWKTAQPDALKGADADTDIACVTMATSAYDSSREAVPLRAAASMVRCYFQREGLVREVTLSGNQWVDIGSVPIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8W3</accession>
    <name>E3Q8W3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CBS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_01972</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091497.1">
        <property type="nucleotide sequence ID" value="XM_008093306.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8W3"/>
    <dbReference type="STRING" id="645133.E3Q8W3"/>
    <dbReference type="GeneID" id="24407337"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01972"/>
    <dbReference type="eggNOG" id="ENOG502QVK2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009026_1_0_1"/>
    <dbReference type="OrthoDB" id="418595at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17781">
        <property type="entry name" value="CBS_pair_MUG70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17782">
        <property type="entry name" value="CBS_pair_MUG70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06409">
        <property type="entry name" value="PB1_MUG70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051462">
        <property type="entry name" value="CBS_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48108">
        <property type="entry name" value="CBS DOMAIN-CONTAINING PROTEIN CBSX2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48108:SF26">
        <property type="entry name" value="CBS DOMAIN-CONTAINING PROTEIN DDB_G0289609"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00666">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="657"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="104"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="171"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="275"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="340"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="450"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="582"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="66"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="82"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="618"/>
            <end position="630"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ27477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="682" mass="73431" checksum="8235677DF9230687" modified="2011-01-11" version="1">MSGNTLRGTPNRGQARGSIPFTQSPSVTGPATPSTSSGIPRPVLETQATQSEVGGSGVSASRQKQTKRDEAIRKKMESDLSKKKHLTSRARHSRKAPPGTVLALKPSQALQIKPGTSVAEAAQLMAAKREDCVLVTDDDDRIAGIFTAKDLAFRVVGAGQKPSHITIAEIMTKNPLCARTDTSATDALDLMVRKGFRHLPVMDENQDISGILDITKCFYDAMEKLERAYSSSRRLYDALEGVQSELGTSQPQQIIQYVEALRSKMSGPTLESVLDGRPPTTVSVRTSVREAAQMMKDNRTTAVLVQDQGAITGIFTSKDVVLRVIAPGLDPATCSVVRVMTPHPDFAPMDMSIQAALRKMHDGHYLNLPVMNDGGEIVGMVDVLKLTYATLEQINTMSTSDSEGPAWNKFWLSLDDGTESMMSGEGSHTHHTNLGSRIMSPDISRERIGDSVAPGDSASHVGLESPPRSAITGHSPVHQSPAELPFPFKFKAPSGRVHRLQVIASQGIAAMVTNVISKLGSEVDSIGGAPTVEEGRISGGFALSYLDDEGDSVSITTDNDLLESILLARQGHREKVDLFVHDPEKPPVSAAPPTIEPVALPTPPISATPDLRRRRAYDDEDDEAEDEDDDVSHVRRSRRARHAAEPEQVIAGVPNELLLPGAIVTLAVVIVGVFTISRLTSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9I5</accession>
    <name>E3Q9I5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycosyltransferase family 28 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_01859</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091384.1">
        <property type="nucleotide sequence ID" value="XM_008093193.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9I5"/>
    <dbReference type="STRING" id="645133.E3Q9I5"/>
    <dbReference type="GeneID" id="24407224"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01859"/>
    <dbReference type="eggNOG" id="KOG1192">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000537_1_0_1"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016906">
        <property type="term" value="F:sterol 3-beta-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000268">
        <property type="entry name" value="Glycosyltransferase family 1 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000009">
        <property type="entry name" value="Sterol 3-beta-glucosyltransferase UGT80A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010610">
        <property type="entry name" value="EryCIII-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050426">
        <property type="entry name" value="Glycosyltransferase_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050:SF13">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE UGT80A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06722">
        <property type="entry name" value="EryCIII-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyltransferase family 28 N-terminal" evidence="3">
        <location>
            <begin position="99"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="Erythromycin biosynthesis protein CIII-like C-terminal" evidence="4">
        <location>
            <begin position="419"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="643"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="677"/>
            <end position="686"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ27364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="914" mass="100163" checksum="EB0F2B47497E5C7D" modified="2011-01-11" version="1">MSLSRVTSKGLGHIQLGSGDRSDTTTTGNVGNDGRVKVRFHENPQTLAAWFRNAQGAFRPPSIDNSCREDDGGRVRRHSSVVFENLRQHPPAASPRLNIAIHIVGSRGDIQPFIPIAQLLMQPPYGHRVRICTHPVFKEFVESNGVEFFSIGGDPEALMAYMVKNPGLLPSRESVKAGDIGQRRKEMAEIINGAWRSCIEAGDGMGERTTAATVKDANHLFVADAIIANPPSMAHIHCAQKLGVPLHMVFTMPWCPTQAFHHPLASMSYGDADKSVANYLSFIMMELLTWQGLGDVINKFRTQTLGLDHISPMWGCQLLPRLRVPYTFLWSESLIPKPKDWDSHINITGFSFLPLADKYTPPPDLTAFLESGPPPVYIGFGSIVVDDPKALTQLIFKAVEIAGVRAIVSKGWGGVGGSHNVPDDVYLIGNCPHDWLFKRVSAVVHHGGAGTSAAGIAAGRPTVVVPFFGDQPFWGQMIARAGAGPAPVPFKEMTAETLASSITFALKPEVQVAVQQMAQRIAEEDGAGDTARGIQERLAIDTMRCDICPERLAVWRHKKTGAHLSGFAVTCLIDQGYMKPHEMKLLRQKHWYVDEGAESPIIGLVAAAAGFFTAVGTATSDYSQRLRNPQPSMRVRETEIDFEDQLGQGKPAEGEINTTREASVEPSGEGEANPADGHAKKIERRSTMTPRQLKSLAMKMATKSLRCANPAAELALEDLTKRGRRKKSVMSIGKRQRSRPMEITRATGRYGIEVAKAGLKAPVAVFYNVANGFHNFPSYGFAGHDVRRRDEITGLGSGLRTAGKEFALGGWEAFSGVIVKPYKGAKNEGIKGFGKGTWQALRGFTYNIFAGLFGLPGYTLKGLEKELSKHRLTELRAEVMLIQLRRGMVDYRTSTEADREEVIVRWKEFLSARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9T8</accession>
    <name>E3Q9T8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rab GDP dissociation inhibitor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_02770</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Rab GDI family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091646.1">
        <property type="nucleotide sequence ID" value="XM_008093455.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9T8"/>
    <dbReference type="STRING" id="645133.E3Q9T8"/>
    <dbReference type="GeneID" id="24408135"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02770"/>
    <dbReference type="eggNOG" id="KOG1439">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021695_0_1_1"/>
    <dbReference type="OrthoDB" id="9446342at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005093">
        <property type="term" value="F:Rab GDP-dissociation inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.405.10:FF:000001">
        <property type="entry name" value="Rab GDP dissociation inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.405.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.519.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018203">
        <property type="entry name" value="GDP_dissociation_inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000806">
        <property type="entry name" value="RabGDI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787:SF8">
        <property type="entry name" value="RAB GDP DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787">
        <property type="entry name" value="RAB GDP-DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00996">
        <property type="entry name" value="GDI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00892">
        <property type="entry name" value="RABGDI"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00891">
        <property type="entry name" value="RABGDIREP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ27626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="464" mass="51091" checksum="0A1DF3FE6BC464FC" modified="2011-01-11" version="1">MDEIAKEYDVIVLGTGLTECILSGVLSVKGKKVLHIDRNDHYGGEAASVNLETLFKKYGNYAQGEEPWTKYGRLNDWNIDLVPKFLMSAGELTNILVSTDVTRYLEFKQVAGSYVQQGQSSKATVAKVPSDAGEALRSPLMGIFEKRRMKSFIEWIGTFDIKDPATHKGLDINTVAMKEVYDKFGLETGTRDFIGHAMALFTTDDYLNKPGAAPEAIERIRLYGTSVARYGKSPYIYPLYGLGELPQGFARLSAIYGGTYMLNTNVDEVQYEGGKAVGIKATMTGVEEMKFETKAKMILGDPSYFPGKVKVVGQVLRAICILKHPLAGTNDADSAQLIIPQSQIGRKNDIYIACVSSAHNVCPKGYWIAIVSTIAETNANHHVELQPGLERLGQIEEQFMGAPIPIYEPTDDGTSDNVFVSKSYDASSHFESTTDDVKDIYRRATGEELKVEGLREGLQVAAEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAQ6</accession>
    <name>E3QAQ6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">LPXTG-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_03088</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ27944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091964.1">
        <property type="nucleotide sequence ID" value="XM_008093773.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAQ6"/>
    <dbReference type="GeneID" id="24408453"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03088"/>
    <dbReference type="eggNOG" id="ENOG502SSVT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031222_1_0_1"/>
    <dbReference type="OrthoDB" id="5239590at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180352" description="LPXTG-domain-containing protein" evidence="3">
        <location>
            <begin position="20"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="351"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="413"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ27944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="423" mass="45758" checksum="8CF09E47B90E7B12" modified="2011-01-11" version="1">MRLAPSTIVLGVWLGHASAIHVAEGSPCQTLCGNVLDATTETDVVCSESGYSVGAGPVYQQCVSCELTSDYSTATQTDTQWLLYNLRYAVSYCLFGYPYNPDVGSSPCLTRTACEPLQNAVMYNDLAPNGTEYDYCSAWNHNQVGSCAACLRAGENHYLTNFLTILDAGCQQRPEPGATISVEGSPFSKTPVNATEPSPTNTYVSNYNSGPISLGGKVGIAIGGVVLILAIAGFCIVWNGKRRRRAFLKQLEMKQKGPAAWPSPLNTVGINGTPLSQRPLRSWDDTPSTQGPTRGWDDSPLSPQAEKAFPRYFSPYSSQYNSPVSGNEAPSTQWPVDQAASRAQPLEIGVALGGDGSGNNWSEPKGKGRSESYELRDIEGDWDARQRHPSPPVLQHPGHSRYAEHNPAAYHGLTEEDIRRGYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBM7</accession>
    <name>E3QBM7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">6-methylsalicylate decarboxylase</fullName>
            <ecNumber evidence="7">4.1.1.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_03510</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>6-methylsalicylate + H(+) = 3-methylphenol + CO2</text>
            <dbReference type="Rhea" id="RHEA:23112"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17231"/>
            <dbReference type="ChEBI" id="CHEBI:36658"/>
            <dbReference type="EC" id="4.1.1.52"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:23113"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. ACMSD family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.52" evidence="7"/>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092386.1">
        <property type="nucleotide sequence ID" value="XM_008094195.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBM7"/>
    <dbReference type="STRING" id="645133.E3QBM7"/>
    <dbReference type="GeneID" id="24408875"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03510"/>
    <dbReference type="eggNOG" id="KOG4245">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039329_2_0_1"/>
    <dbReference type="OrthoDB" id="2832284at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047596">
        <property type="term" value="F:6-methylsalicylate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019748">
        <property type="term" value="P:secondary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032465">
        <property type="entry name" value="ACMSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240">
        <property type="entry name" value="2-AMINO-3-CARBOXYLMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240:SF29">
        <property type="entry name" value="AMIDOHYDROLASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="9">
        <location>
            <begin position="4"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00036832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ28366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="328" mass="36405" checksum="AEC2632DDDBC156D" modified="2011-01-11" version="1">MERIDIHCHAVPAGYRQYALDNGHEKPDGMPALPDWTPEEHIALMKSLNISKSILSITSPGTHLTPNQDRHAAGMTRQTNEELAAICKQHPSHFGFFASLPLPSVQESVAEMDYALDVLGAVGFAVMSNASGVYLGDRALDPIFERLHQRKAILFIHPTTCNLLSAGGQVQPMKPLEEYPRPMMEFMFDETRAIANLLLSSTVSKYPGITFIMSHGGCVLPSIVDRIGAFATFNGGENRSEEFRGLLRERFFFDMAGFPFPDQVHGLLRTLGQGGERRLVYGSDYPFTPGKVVLDLGAKMDQGCKELFDEDQRQAVYSGNAERMLRQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCE3</accession>
    <name>E3QCE3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TGS domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_03675</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092551.1">
        <property type="nucleotide sequence ID" value="XM_008094360.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCE3"/>
    <dbReference type="STRING" id="645133.E3QCE3"/>
    <dbReference type="GeneID" id="24409040"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03675"/>
    <dbReference type="eggNOG" id="KOG1487">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044997_0_0_1"/>
    <dbReference type="OrthoDB" id="603at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903833">
        <property type="term" value="P:positive regulation of cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd01896">
        <property type="entry name" value="DRG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17230">
        <property type="entry name" value="TGS_DRG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000003">
        <property type="entry name" value="Developmentally-regulated GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000740">
        <property type="entry name" value="Putative GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045001">
        <property type="entry name" value="DRG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031662">
        <property type="entry name" value="GTP-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006074">
        <property type="entry name" value="GTP1-OBG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43127">
        <property type="entry name" value="DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16897">
        <property type="entry name" value="MMR_HSR1_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="TGS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00905">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="3">
        <location>
            <begin position="50"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="4">
        <location>
            <begin position="276"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ28531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="353" mass="38841" checksum="0077256AC58CE1FE" modified="2011-01-11" version="1">MAKTQKNKATSFHLGQLKAKLAKLKRELLTPSGGGGGGGAGFDVARTGVASIGFIGFPSVGKSTLMSKLTGQHSEAAAYEFTTLTSVPGQVTYNGAPLQIIDLPGIIEGAKDGRGRGRQVIAVAKTCHLIFIVLDVNKPLTDKRIIETELEGFGIRINKSPPNITFKKKEKGGLNITSTVPLTHIDHDEIKAVMNEYRINSADIAIRCDATIDDLIDVLEAKSRNYIPVIYVLNKIDAISIEELDLLYRIPNAVPISSEQGWNIDELMEAMWEKLQLVRVYTKPKGKLPDYSQPVVLRSNRCTVEDFCNQIHRSILEQFKTAIVYGKSVKHQPQRVGLAHELADEDIVTIVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCG8</accession>
    <name>E3QCG8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Hyaluronan/mRNA-binding protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_03700</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092576.1">
        <property type="nucleotide sequence ID" value="XM_008094385.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCG8"/>
    <dbReference type="STRING" id="645133.E3QCG8"/>
    <dbReference type="GeneID" id="24409065"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03700"/>
    <dbReference type="eggNOG" id="KOG2945">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043312_1_1_1"/>
    <dbReference type="OrthoDB" id="5426471at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039764">
        <property type="entry name" value="HABP4/SERBP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006861">
        <property type="entry name" value="HABP4_PAIRBP1-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019084">
        <property type="entry name" value="STM1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12299:SF17">
        <property type="entry name" value="AT19571P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12299">
        <property type="entry name" value="HYALURONIC ACID-BINDING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09598">
        <property type="entry name" value="Stm1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01233">
        <property type="entry name" value="HABP4_PAI-RBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hyaluronan/mRNA-binding protein" evidence="4">
        <location>
            <begin position="106"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="194"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="105"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="116"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="230"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="262"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="276"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="288"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="302"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ28556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="324" mass="34358" checksum="3E1285CEECAA6EBE" modified="2011-01-11" version="1">MSVASKNLFELLGNDAEDDTPQAPVKTVDKTTMRSTKRGVEPEAPTRAAGNTGARRTNVSGNEAAFRDRGAGSDRNRGKTTEEPARGGPRGGYGARARGGRGGRFPRERDDRQPKNIVSGSEKQAAQSWGATEGEAERKDEVAGEAIAQAEAKDAEAEAAAPVEPEEPEEKHISYADYLAQQAEKKLALESGSEIRKANEGTKLKKEWANAKEVTRDDDDTFMIGTGGKTKRERERKTKQLLDIDQRYVEPERPRGGDRGGPRGGARGGARGGARGGDRGGRGRGDGPRGGAPRAGGAPRGGRREGGAQINTKDESAFPSLGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCJ5</accession>
    <name>E3QCJ5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">4-aminobutyrate aminotransferase</fullName>
            <ecNumber evidence="3">2.6.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">GABA aminotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Gamma-amino-N-butyrate transaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_03727</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:23352"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57706"/>
            <dbReference type="ChEBI" id="CHEBI:59888"/>
            <dbReference type="EC" id="2.6.1.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.19" evidence="3"/>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092603.1">
        <property type="nucleotide sequence ID" value="XM_008094412.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCJ5"/>
    <dbReference type="STRING" id="645133.E3QCJ5"/>
    <dbReference type="GeneID" id="24409092"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03727"/>
    <dbReference type="eggNOG" id="KOG1405">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016922_12_0_1"/>
    <dbReference type="OrthoDB" id="10260828at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034386">
        <property type="term" value="F:4-aminobutyrate:2-oxoglutarate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009450">
        <property type="term" value="P:gamma-aminobutyric acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000029">
        <property type="entry name" value="4-aminobutyrate aminotransferase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004631">
        <property type="entry name" value="4NH2But_aminotransferase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049704">
        <property type="entry name" value="Aminotrans_3_PPA_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00699">
        <property type="entry name" value="GABAtrns_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43206:SF1">
        <property type="entry name" value="4-AMINOBUTYRATE AMINOTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43206">
        <property type="entry name" value="AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="7 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ28583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="504" mass="55693" checksum="CEF7B868BEECC717" modified="2011-01-11" version="1">MVFTRASAAMARPAIRAARSSAAAFPRRSLCASVPRMAAASLFPGEPSGPSVKTEIPGPASKKHTEDLHKVFDTRSLNMLTDYKKSKGNYIVDADGNVLLDVYAQIASIPLGYNNPVLAKVAQTPEMVNAIINRPALGNFPPEDWAETLRSGILKVAPKGLDQVFTAMAGSDANETAYKAAFMWRRQQERGGYDVDFTPEETSSAMDNKSPGASDLSILSFRTGFHGRLFGSLSTTRSKPIHKLDIPAFDWPQATFPLLKYPLEEHVEENAAAEQAALDEVEHLIKTYHVPPAAVIVEPIQSEGGDNHASPAFFRGLREVTKRHNVLLIVDEVQTGVGATGRFWAHDHWDLPTPPDMVTFSKKAQTAGYYFGNPELRPNKPYRQFNTWMGDPARAILFRAIIDEIDRLGLVEHTARVGDYLFSKLEGLAAKYPDQFDNLRGKGQGTFIAFDNPRRDEFLKRAKGLGINIGGSGERAVRLRPMLIFQEHHADILIEALEKIAKSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCT5</accession>
    <name>E3QCT5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_03817</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092693.1">
        <property type="nucleotide sequence ID" value="XM_008094502.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCT5"/>
    <dbReference type="STRING" id="645133.E3QCT5"/>
    <dbReference type="GeneID" id="24409182"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03817"/>
    <dbReference type="eggNOG" id="KOG1205">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_48_0_1"/>
    <dbReference type="OrthoDB" id="1274115at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05374">
        <property type="entry name" value="17beta-HSD-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051911">
        <property type="entry name" value="SDR_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976:SF16">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="270"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="281"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ28673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="309" mass="34082" checksum="4AB41DBB654D2967" modified="2011-01-11" version="1">MGRSLVKSALSKGDLVTSVGRVFETNPEDMAVHQDKDSCLGLLCDVRSRDSVARVVDRTLERFQRVDVVANCSGYGVIGACEDQDEHEIRNQFETNFMGTLNIIQATLPYFRQQNGGRYLIFSSTSGALGVPGLGPYCATKYAVEGLIEAMLYETDSFNVKATLVEPGFVRRDEPDALATPLPTWGHFLIKPASEAYAQATSPALHAKRMVQWLGDRQPTSAVKCAELVWQLAHCSYPPLRLLLGSYAIESIRDRLRSVTEELEDWKHLNFPVGPDLGSESEAKDGKQDQDQSIADSGQDLPGQVTREV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCW1</accession>
    <name>E3QCW1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Translation machinery-associated protein 22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_03877</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2 4">Interacts with the 40S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="4">The SUI1 domain may be involved in RNA binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the DENR family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092753.1">
        <property type="nucleotide sequence ID" value="XM_008094562.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCW1"/>
    <dbReference type="STRING" id="645133.E3QCW1"/>
    <dbReference type="GeneID" id="24409242"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03877"/>
    <dbReference type="eggNOG" id="KOG3239">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073511_0_1_1"/>
    <dbReference type="OrthoDB" id="277199at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001731">
        <property type="term" value="P:formation of translation preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002188">
        <property type="term" value="P:translation reinitiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11607">
        <property type="entry name" value="DENR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.780.10">
        <property type="entry name" value="SUI1-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050318">
        <property type="entry name" value="DENR/SUI1_TIF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046447">
        <property type="entry name" value="DENR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005873">
        <property type="entry name" value="DENR_eukaryotes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048517">
        <property type="entry name" value="DENR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001950">
        <property type="entry name" value="SUI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036877">
        <property type="entry name" value="SUI1_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01159">
        <property type="entry name" value="DRP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12789:SF0">
        <property type="entry name" value="DENSITY-REGULATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12789">
        <property type="entry name" value="DENSITY-REGULATED PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21023">
        <property type="entry name" value="DENR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01253">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55159">
        <property type="entry name" value="eIF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50296">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="SUI1" evidence="6">
        <location>
            <begin position="103"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="70"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ28733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="196" mass="21518" checksum="D40D1F169EFEDBEA" modified="2011-01-11" version="1">MADNDKPETSGEPQGRHVIYCGVCTLPPEYCEYGGTVKKCQDWLEKHHPDLYANIWSQEALEAATASLSVDAQKRAAKDAQKKAAKAEAAEAKQADKLAKSVVTIKRIERNKRKFVTSVSGLESFGLENKKVAKEFGKKFATGSSVTKTPSGGEEIVVQGDVSDEIEEFLLEKYKEIPEDNIELVEDKKKKASAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDX8</accession>
    <name>E3QDX8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">General transcription and DNA repair factor IIH subunit TFB5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_04210</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.</text>
    </comment>
    <comment type="function">
        <text evidence="9">In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the 7-subunit TFIIH core complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the TFB5 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093086.1">
        <property type="nucleotide sequence ID" value="XM_008094895.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDX8"/>
    <dbReference type="STRING" id="645133.E3QDX8"/>
    <dbReference type="GeneID" id="24409575"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04210"/>
    <dbReference type="eggNOG" id="ENOG502SBQE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_166246_3_1_1"/>
    <dbReference type="OrthoDB" id="354at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000439">
        <property type="term" value="C:transcription factor TFIIH core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006294">
        <property type="term" value="P:nucleotide-excision repair, preincision complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1220:FF:000002">
        <property type="entry name" value="RNA polymerase II transcription factor B subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1220">
        <property type="entry name" value="TFB5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035935">
        <property type="entry name" value="TFB5-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009400">
        <property type="entry name" value="TFIIH_TTDA/Tfb5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28580">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28580:SF1">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06331">
        <property type="entry name" value="Tfb5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01395">
        <property type="entry name" value="Tbf5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142897">
        <property type="entry name" value="TFB5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 9" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU368032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ29066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="71" mass="8104" checksum="A47D4CA9D54E7BAE" modified="2011-01-11" version="1">MPRAIRGVLIECDPSIKSIIVNIDSNNHDYIIEDLDDQHVVVKENMVAALKRQLDERLKETQQPDESSDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEZ5</accession>
    <name>E3QEZ5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nuclear pore complex protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_04360</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Functions as a component of the nuclear pore complex (NPC).</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the nuclear pore complex (NPC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
            <location evidence="7">Nuclear pore complex</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Nucleus membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the nucleoporin Nup84/Nup107 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093236.1">
        <property type="nucleotide sequence ID" value="XM_008095045.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEZ5"/>
    <dbReference type="STRING" id="645133.E3QEZ5"/>
    <dbReference type="GeneID" id="24409725"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04360"/>
    <dbReference type="eggNOG" id="KOG1964">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005882_1_0_1"/>
    <dbReference type="OrthoDB" id="3098at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031080">
        <property type="term" value="C:nuclear pore outer ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000973">
        <property type="term" value="P:post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3450.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.190.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007252">
        <property type="entry name" value="Nup84/Nup107"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13003:SF2">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13003">
        <property type="entry name" value="NUP107-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04121">
        <property type="entry name" value="Nup84_Nup100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="5 7" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0811">Translocation</keyword>
    <keyword evidence="1 7" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="63"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ29216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="894" mass="101221" checksum="59C32D78242353E9" modified="2011-01-11" version="1">MYGPLGPETEVFANALDDCLAPQGTVEEKHARILDLVDAYYEYADHTLTALRRQVRQGSAGDTEMDLDEDEDADPAASIEEIRGWEQERQTWDLIRRLIPLRYSARKATGKQASIVTKDGEGDDIWRAFLANDRLAVERKTILEWLQHNARTGPDLDDLVRELQQNADRGDIIAHGWIHTRSAIKLQKSVIGSTRPLDVQFPEVSRSLVNSDKAPLVAELDPDSVTRQCRKLEPQDEYFERAIWVGCFQLLRRGSSLEDMREWCLERTEVWRAVSMSALPLATKHGEENSMEDPSALALWRRICFAAARHGGTDDIERAVYGVLSGDIPSVQKVCKTWDDFMFMHYNALLRTQFDTFVLGQCPPEVSTSLRSSFAAFDAVQFHGDPSTLEQRLVHSLETNPQTGHEALEPVKTLQAAIITKELEKHFYEQGVAITLKANSKESSALMPDNSCHDVSVVPEKFADFENPGRLRLAVHALIIFGTLDKLVDSPPNSSTMSWRPDRREIQENTITLYISLLRLSGLEELIPLYCSRIRDQRALQVLSTNLLPITDNEARLVQLSLIRKAGLDVLEFVKYQPASLFRCIDVDTAKIQTFQILDNGPPSLKYGRSIRTDFFGEDPDTIDSIDERLIRSVEWLLLVDEAWPHVFCVGVDIYKYFLRTMRLNAARSFANRVPFSTIMRQRVELPEQDDNDPWWPEDAEFWAGQIEAAGAKSLSPSQIASEARAFRELECLVKALDTMETIASLAELSKEDPSVKRDFWAKVGNEVKSAKEHVRPLLKNWLRSQEDTELESLRDMYLPETLLAFISSLHFAGTTLTRDNFLECMELAATIAEKGSDVAECFMKANRMKELVESFAACSKALAIASSEKKTAGSSSKKLREMGWTRDIWSVKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFH5</accession>
    <name>E3QFH5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04757</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093633.1">
        <property type="nucleotide sequence ID" value="XM_008095442.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFH5"/>
    <dbReference type="GeneID" id="24410122"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04757"/>
    <dbReference type="eggNOG" id="ENOG502R0YU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_874384_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="272"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="70"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="120"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="318" mass="33049" checksum="DDB05223519BF620" modified="2011-01-11" version="1">MPHLPWHLHPIQSSSSASTKLHPSVRISTSTRSAILLSTSSISRVQNTRARPSSLIRTSLSRTICTTAVSSSPSSLSPSAPASAAPNLSRTSLSTSSPTAASTWPRTSSANRPRSNSKLSCTPCATSPRTSSRSRIRAASGLVNVPLRIRTSPSASTLRFEAADDGGDGEHDDEDGHDDAGLVSVSTTRRCATVRVLLGVRKADGLGWGEGSSIPPTGVTGRPPDVGVAEREGACSGDQAVRESSARISVEARGRRVVRPRAKGARALRGIPWPMSRKKGSTSMTSAGISRPRSAPGAGGRFVEGFLSIGIAVSVVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFS1</accession>
    <name>E3QFS1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Triose-phosphate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_04900</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homooligomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TPT transporter family. SLC35D subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093776.1">
        <property type="nucleotide sequence ID" value="XM_008095585.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFS1"/>
    <dbReference type="GeneID" id="24410265"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04900"/>
    <dbReference type="eggNOG" id="KOG1441">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022332_0_2_1"/>
    <dbReference type="OrthoDB" id="6418713at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="84"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="141"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="164"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="239"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="264"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="290"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="345"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="9">
        <location>
            <begin position="19"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ29756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="382" mass="41921" checksum="FCE839AEF0ABB41F" modified="2011-01-11" version="1">MSTLPTTEKPGGSKALHPAFFIASWIFFSNLTILFNKWLLDTAGFTVILTCWHLVFSTLATQILARTTSLLDDRHKVKMTGRVYLRAVVPIGLLYSGSLVCSNLVYLYLSVSFIQMLKAGAPVAVLFTSWAWGVADPSTKTLYNILLIVAGVALASFGEIEFSWIGFIFQMGGIVFEAIRLVMIQVLLKGDENAQRMNPLVSLYYYAPVCAVMNFFVAWASEFSTFKFEDLQKTGVTMLLLNAAVAFMLNVSSVFLIGKTSGLVMTLTGILKNILLIVASVIIWRTSITVMQFVGYAIALFGLVIYSTGWEQLKSSGVAAITWARTAWNSHNFDEGRLSPLVRRALVLGLITLITLMLVLGIAYKGSSAPEDWLPTVAAVST</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QG29</accession>
    <name>E3QG29_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Putative gamma-glutamylcyclotransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_05008</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the gamma-glutamylcyclotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093884.1">
        <property type="nucleotide sequence ID" value="XM_008095693.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QG29"/>
    <dbReference type="GeneID" id="24410373"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05008"/>
    <dbReference type="eggNOG" id="ENOG502S7T1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093936_1_2_1"/>
    <dbReference type="OrthoDB" id="1044435at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06661">
        <property type="entry name" value="GGCT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.10">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045038">
        <property type="entry name" value="AIG2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009288">
        <property type="entry name" value="AIG2-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013024">
        <property type="entry name" value="GGCT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036568">
        <property type="entry name" value="GGCT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31544">
        <property type="entry name" value="AIG2-LIKE PROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31544:SF2">
        <property type="entry name" value="AIG2-LIKE PROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06094">
        <property type="entry name" value="GGACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110857">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Gamma-glutamylcyclotransferase AIG2-like" evidence="5">
        <location>
            <begin position="8"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00030602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ29864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="185" mass="20814" checksum="E7C283746203BC0A" modified="2011-01-11" version="1">MSGPHTAFFYGTLMEPKVFFTVVQGDSNPPQAIKDLYTFTPAVLTGHTRHRVQDAAYPGMIPEEGGSVLGIYATGLTDANVSKLDLFEGSEYEKKVVKVKLQGGGSGGQEGEEEKEATAYIYKRPEFLERREWSFDEFRRDKMHIWTRESYVFEGCTDSAEFEKTKHEDTQGHDDKDDAVKQNGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3QG96</accession>
    <name>E3QG96_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 17">Homoaconitase, mitochondrial</fullName>
            <ecNumber evidence="5 17">4.2.1.36</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16 17">Homoaconitate hydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">GLRG_04836</name>
    </gene>
    <organism evidence="21">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 17">Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15 17">
            <text>(2R,3S)-homoisocitrate = cis-homoaconitate + H2O</text>
            <dbReference type="Rhea" id="RHEA:15485"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15404"/>
            <dbReference type="ChEBI" id="CHEBI:58174"/>
            <dbReference type="EC" id="4.2.1.36"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="17">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 17">Amino-acid biosynthesis; L-lysine biosynthesis via AAA pathway; L-alpha-aminoadipate from 2-oxoglutarate: step 3/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 17">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 17">Belongs to the aconitase/IPM isomerase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.36" evidence="5 17"/>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093712.1">
        <property type="nucleotide sequence ID" value="XM_008095521.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QG96"/>
    <dbReference type="STRING" id="645133.E3QG96"/>
    <dbReference type="GeneID" id="24410201"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04836"/>
    <dbReference type="eggNOG" id="KOG0453">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006714_3_1_1"/>
    <dbReference type="OrthoDB" id="10262323at2759"/>
    <dbReference type="UniPathway" id="UPA00033">
        <property type="reaction ID" value="UER01027"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004409">
        <property type="term" value="F:homoaconitate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01674">
        <property type="entry name" value="Homoaconitase_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.499.10:FF:000013">
        <property type="entry name" value="Homoaconitase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="entry name" value="Aconitase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="entry name" value="Aconitase, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004418">
        <property type="entry name" value="Homoaconitase_mito"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039386">
        <property type="entry name" value="Homoaconitase_swivel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050067">
        <property type="entry name" value="IPM_dehydratase_rel_enz"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00139">
        <property type="entry name" value="h_aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43822:SF2">
        <property type="entry name" value="HOMOACONITASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43822">
        <property type="entry name" value="HOMOACONITASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="Aconitase iron-sulfur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52016">
        <property type="entry name" value="LeuD/IlvD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 17" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 17" id="KW-0408">Iron</keyword>
    <keyword evidence="11 17" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="14 17" id="KW-0456">Lyase</keyword>
    <keyword evidence="13 17" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="8 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 17" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 17" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha" evidence="18">
        <location>
            <begin position="77"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase A/isopropylmalate dehydratase small subunit swivel" evidence="19">
        <location>
            <begin position="588"/>
            <end position="704"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00029338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00032706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU362038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EFQ29692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="785" mass="84327" checksum="8378E97F26846E79" modified="2011-01-11" version="1">MLPIRRSVALQATRSCRTIFQRQIVSPRTFRPSFYTTSARLRQNAFPSHTETGPTATDFLVSKPTLKIENPQTLTEKIVQRYAVGLAPGKKVRAGDYVTIKPGACMTHDNSFPVAKKFMGLGAEKIRDPSMVVFTLDHDVQNKSPQNLEKYRLIEEFAKKHGIDFYGAGRGIGHQVMVEEGYAWPGTMAVGSDSHSNIYGGIGCLGTPVVRTDAASIWATGRTWWQVPPIAKITFTGTLPHGVTGKDVIVALCGLFNKDEVLNHAIEFAGSEETMRSLPVDARLTISNMSTEHGALSAMFPIDATLEAWLRARATVSAMVSPDGKAHSRLSHERIDSLFENPVTADPGATYAKSLYMDLSTLSPFVAGPNSVKAVTPLKDLEAQDVKIDKAYLVSCTNSRASDIAAAARVFREASKNGQPAKIAPGVKFYLAAASSLVQEAAEEAGDWQVLHEAGAELLPAGCGPCIGLGTGLLEPGEVGISASNRNFKGRMGSTEAKAYLASPEVVAASALQGKIAGPGWYEKPEGVDKVIIGEGVGNMTADIATSIEDALEKLISQADSIIAESEKGLSGAPAGDTAAAEGEETLTEILPGFPEKVEGEIVFCDADNLNTDGIYPGKYTYQDNVSVEKMAEVCMENYDTSFRDIAKAGDILVSGFNFGTGSSREQAATAILAKKIPLVVAGSFGNIFSRNSINNALMGVEVPKLVQRLRETFKGEDGDKVLTRRTGWKLKWDVRRSKVTVTEKSGETWSVKVGELPPNVQEIIACGGLEEWVKADIRKESANN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGH1</accession>
    <name>E3QGH1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA-directed RNA polymerase II subunit RPB3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_05103</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ29959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093979.1">
        <property type="nucleotide sequence ID" value="XM_008095788.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGH1"/>
    <dbReference type="STRING" id="645133.E3QGH1"/>
    <dbReference type="GeneID" id="24410468"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05103"/>
    <dbReference type="eggNOG" id="KOG1522">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038421_1_1_1"/>
    <dbReference type="OrthoDB" id="270173at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07031">
        <property type="entry name" value="RNAP_II_RPB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.120.12:FF:000002">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.12">
        <property type="entry name" value="DNA-directed RNA polymerase, insert domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="entry name" value="RNA polymerase, RBP11-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00320">
        <property type="entry name" value="RNApol_arch_Rpo3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001514">
        <property type="entry name" value="DNA-dir_RNA_pol_30-40kDasu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011262">
        <property type="entry name" value="DNA-dir_RNA_pol_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011263">
        <property type="entry name" value="DNA-dir_RNA_pol_RpoA/D/Rpb3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022842">
        <property type="entry name" value="RNAP_Rpo3/Rpb3/RPAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036643">
        <property type="entry name" value="RNApol_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050518">
        <property type="entry name" value="Rpo3/RPB3_RNA_Pol_subunit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001988">
        <property type="entry name" value="PRK00783.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11800">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11800:SF2">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01000">
        <property type="entry name" value="RNA_pol_A_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01193">
        <property type="entry name" value="RNA_pol_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00662">
        <property type="entry name" value="RPOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56553">
        <property type="entry name" value="Insert subdomain of RNA polymerase alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="RBP11-like subunits of RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00446">
        <property type="entry name" value="RNA_POL_D_30KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase RpoA/D/Rpb3-type" evidence="9">
        <location>
            <begin position="26"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="299"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="299"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="320"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00072506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ29959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="339" mass="37193" checksum="00E3FD7A4D5293FA" modified="2011-01-11" version="1">MDYEPMLLDGESGGPSIKISGADNIHVNFDLSNCDLSFANSLRRVIQAEVPVIAIDLVEIEANTSVLADEFIAHRLGLIPLQSKDVNSLLYTRDCDCEQYCDNCSVKLTLHARCSSDDTMKVYASDLIVDSFRQNGTVGNPVILDPEGQGSLICKLRKGQELKISCIAKKGIAKEHAKWMPTSAVGFEYDPHNKLHHLDMWYEEDAKAEWPDSKYAKMEDPPQEGDPFDYDAVPGKFYFEVEGVGSLEPDQIIQEGIKILQEKLALTLHILTGEADDDGMGDFDGPRSPNLDMDGGNPWQDQGYTTPFNGGGQSSWGGNATTPYATTTPYGASGQSGWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGV8</accession>
    <name>E3QGV8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_05240</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ30096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094116.1">
        <property type="nucleotide sequence ID" value="XM_008095925.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGV8"/>
    <dbReference type="GeneID" id="24410605"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05240"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_43_5_1"/>
    <dbReference type="OrthoDB" id="5290825at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015798">
        <property type="term" value="P:myo-inositol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015791">
        <property type="term" value="P:polyol transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000100">
        <property type="entry name" value="MFS sugar transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050814">
        <property type="entry name" value="Myo-inositol_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020:SF25">
        <property type="entry name" value="SUGAR TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G05830)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="126"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="202"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="265"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="388"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="421"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="452"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="479"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="518"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="550"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="130"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="41"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ30096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="642" mass="72325" checksum="9368A48F93C954F9" modified="2011-01-11" version="1">MASDSKREKLGDRPPSDQDQTEISHMDHPGRFSEATAIDEEERKRLEASRKLENPLSGLTPEQLAQNGEEYCREHGIGDEEDIRAFRLGAMIAGNMNKYDTMAELTAQERAVLDGETTHKWRNPKMLYGVVAVCSFCAVVQGMDETVVNGAQSFYKGQFGIGGKSERDTWLLGLTNSAPYLCCALIGCWLTEPMNKAFGRRGTVFISCLISALACFWQAFTNTWWHMFIARFALGFGIGPKSATTPIFAAECAPPRLRGALVMQWQMWTAFGIMIGYVADLAFYYVPDRGGIVGLNWRLMMGSAMIPAVLVCGCCYLCPESPRWYLTKGRQFDAYKAMCQLRFEKVQAARDLFYANALLQAEKEFQGIGKQNRFKEFYAIRRNRNAMVASEIVMFMQQFCGVNAIAYYSSEIFLAAEFSEVSALAASLGFGIINWLFALPAFYTIDTFGRRNLLLTTFPLMAICLFFTGFSFYIPTNPAKIACIATGIYLFGMVYSPGEGPVPFTYSAEAYPLYIRSIGMSLATATTWFFNFILAVTWPSLQESFTPTGAFGWYAGWNIVGFFLVLFFLPETKEKTLEELDAVFSVPLRRFARYGLAQFVFFWKRYVFRQDLAPPAVPLAGDVAYHREQFKQEKENNATARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QH20</accession>
    <name>E3QH20_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_05326</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697348">
        <property type="protein sequence ID" value="EFQ30182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094202.1">
        <property type="nucleotide sequence ID" value="XM_008096011.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QH20"/>
    <dbReference type="STRING" id="645133.E3QH20"/>
    <dbReference type="GeneID" id="24410691"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05326"/>
    <dbReference type="eggNOG" id="KOG1515">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012494_6_1_1"/>
    <dbReference type="OrthoDB" id="433474at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="91"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ30182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="331" mass="35184" checksum="7C60176C57039939" modified="2011-01-11" version="1">MSSENLLPRPPYDPQLVPALERINPYPRSVDEIVGGRQLRAALMAPVQAAIRNDEGLLVEDRTIPGPGGELPLVIVQSRSPKTASGERPGIVYFHPGGMVIGDAFLAIEPFVRIARELDAIVVSVEYRLAPEHPAPAPQDDCYAGLVWTSEHAAALGIDPARLMVAGVSGGGGLAAGAALRARDDAAGPKLCAQLLVYPMLDDRDTGVSKRQFRNDTAYDATDNQGAWTCVLGDKAGVEGADVSPYVAPGRATDLSGLPPAYIDVGTAEPFRDENVAYATKLWDSGVQADLHVWSGGFHGFDLMGLAVGSEVAKVALETRMGWVRRILGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QH42</accession>
    <name>E3QH42_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10 11">Endo-1,4-beta-xylanase</fullName>
            <ecNumber evidence="4 10 11">3.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_05348</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10 11">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-xylosidic linkages in xylans.</text>
            <dbReference type="EC" id="3.2.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10 11">Glycan degradation; xylan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10 11">Belongs to the glycosyl hydrolase 11 (cellulase G) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.8" evidence="4 10 11"/>
    <dbReference type="EMBL" id="GG697348">
        <property type="protein sequence ID" value="EFQ30204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094224.1">
        <property type="nucleotide sequence ID" value="XM_008096033.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QH42"/>
    <dbReference type="GeneID" id="24410713"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05348"/>
    <dbReference type="eggNOG" id="ENOG502RXA7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052631_0_0_1"/>
    <dbReference type="OrthoDB" id="2115822at2759"/>
    <dbReference type="UniPathway" id="UPA00114"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031176">
        <property type="term" value="F:endo-1,4-beta-xylanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.180:FF:000001">
        <property type="entry name" value="Endo-1,4-beta-xylanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013319">
        <property type="entry name" value="GH11/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018208">
        <property type="entry name" value="GH11_AS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033123">
        <property type="entry name" value="GH11_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001137">
        <property type="entry name" value="Glyco_hydro_11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46828:SF3">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46828">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00457">
        <property type="entry name" value="Glyco_hydro_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00911">
        <property type="entry name" value="GLHYDRLASE11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00776">
        <property type="entry name" value="GH11_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51761">
        <property type="entry name" value="GH11_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8 10 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 10 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10 11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="5 10 11" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179727" description="Endo-1,4-beta-xylanase" evidence="12">
        <location>
            <begin position="20"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="GH11" evidence="13">
        <location>
            <begin position="35"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="121"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ30204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="229" mass="24624" checksum="914C6EA8EAA55616" modified="2011-01-11" version="1">MRSFASFFTTALVVAGALAAPAAKPITTMDLFKRQSTPSSQGTHNGYFYSWWTDGASPVTYTNGAGGSYSVQWQSGGNFVGGKGWQTGGPKTIQYSGTFSPVNNGNSYLTVYGWTRNPLIEYYIVENHGEYNPGSSATPKGQVTSDGSVYQLYESTRVNAPSIDGDQTFKQFWAIRENKRTGGTVTTQNIFDAWKNAGMTIGTSFDYMVVATEGYKSAGSASITVETAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>E3QH63</accession>
    <name>E3QH63_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05369</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697348">
        <property type="protein sequence ID" value="EFQ30225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094245.1">
        <property type="nucleotide sequence ID" value="XM_008096054.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QH63"/>
    <dbReference type="GeneID" id="24410734"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05369"/>
    <dbReference type="HOGENOM" id="CLU_2468939_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="88" mass="9207" checksum="64F904C96D9FCFAB" modified="2011-01-11" version="1">MSATGYKQESRSGGGGGGGGVGDMSMSGRYLPVRESLKGQTNGRICRKRAYRPKGCILVTVPATLRVTRLLSQRPPAGGSLIRSGQVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIC1</accession>
    <name>E3QIC1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Transcription initiation factor IIA subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_05880</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">TFIIA is a heterodimer composed of the large TOA1 and the small TOA2 subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the TFIIA subunit 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094756.1">
        <property type="nucleotide sequence ID" value="XM_008096565.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIC1"/>
    <dbReference type="STRING" id="645133.E3QIC1"/>
    <dbReference type="GeneID" id="24411245"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05880"/>
    <dbReference type="eggNOG" id="KOG3463">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112964_3_1_1"/>
    <dbReference type="OrthoDB" id="586585at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005672">
        <property type="term" value="C:transcription factor TFIIA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000979">
        <property type="term" value="F:RNA polymerase II core promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060261">
        <property type="term" value="P:positive regulation of transcription initiation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd10014">
        <property type="entry name" value="TFIIA_gamma_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10145">
        <property type="entry name" value="TFIIA_gamma_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.190:FF:000001">
        <property type="entry name" value="Transcription initiation factor IIA subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.18.10:FF:000003">
        <property type="entry name" value="Transcription initiation factor IIA subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.18.10">
        <property type="entry name" value="Transcription factor IIA (TFIIA), beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.190">
        <property type="entry name" value="Transcription factor IIA gamma subunit, alpha-helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009083">
        <property type="entry name" value="TFIIA_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009088">
        <property type="entry name" value="TFIIA_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003194">
        <property type="entry name" value="TFIIA_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015871">
        <property type="entry name" value="TFIIA_gsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015872">
        <property type="entry name" value="TFIIA_gsu_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10966">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02751">
        <property type="entry name" value="TFIIA_gamma_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02268">
        <property type="entry name" value="TFIIA_gamma_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009415">
        <property type="entry name" value="Hum_TFIIA_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47396">
        <property type="entry name" value="Transcription factor IIA (TFIIA), alpha-helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50784">
        <property type="entry name" value="Transcription factor IIA (TFIIA), beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="6 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription initiation factor IIA gamma subunit N-terminal" evidence="10">
        <location>
            <begin position="8"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription initiation factor IIA gamma subunit C-terminal" evidence="11">
        <location>
            <begin position="65"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00063181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR009415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ30736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="115" mass="12856" checksum="D334C6E5B9942D81" modified="2011-01-11" version="1">MAAAPQSFYELYRRSSIGLALTDMLDDLISEERIHPQLAMKILANFDQAITEALQKSVKARLTFKGSLSTYRFCDEVWTFLIKNVQFKLDNGGQIVTADKVKIVSCNAKKPGEGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIM1</accession>
    <name>E3QIM1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ras family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_05775</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094651.1">
        <property type="nucleotide sequence ID" value="XM_008096460.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIM1"/>
    <dbReference type="STRING" id="645133.E3QIM1"/>
    <dbReference type="GeneID" id="24411140"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05775"/>
    <dbReference type="eggNOG" id="KOG0094">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041217_10_2_1"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01861">
        <property type="entry name" value="Rab6"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Probable Ras-related protein Rab-6A"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050227">
        <property type="entry name" value="Rab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47977">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0636">Prenylation</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ30631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="209" mass="23244" checksum="ED78E2E6641EF44D" modified="2011-01-11" version="1">MASGASGSYNNPLKKFKLVFLGEQSVGKTSLITRFMYDSFDNMYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDISNAKSFQNTKKWIDDVRAERGNDVIIVLVGNKTDLNDKREVTTQQGEEEAKKNNLMFVETSAKLGHNVKTLFKRIAQALPGMEGTDAAAQASSQMIDVKTTPAQSSQEGCAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIM7</accession>
    <name>E3QIM7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_05781</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094657.1">
        <property type="nucleotide sequence ID" value="XM_008096466.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIM7"/>
    <dbReference type="STRING" id="645133.E3QIM7"/>
    <dbReference type="GeneID" id="24411146"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05781"/>
    <dbReference type="eggNOG" id="ENOG502S739">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_152700_1_0_1"/>
    <dbReference type="OrthoDB" id="5561579at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019727">
        <property type="entry name" value="ATP_synth_F0_fsu_mt_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28161">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT F, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28161:SF1">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT F, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10791">
        <property type="entry name" value="F1F0-ATPsyn_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ30637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="102" mass="11223" checksum="976F10CE6C57F4A8" modified="2011-01-11" version="1">MSFVPRRGLSTLIPPKVASPKALGADPNAVRMQRVVNFYEKLPRGPAPEAKATGILGRYAAKHFNGKNASAKPIIHALGLLLVIGYAQNYYFHLRHHKNNAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJ15</accession>
    <name>E3QJ15_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_05997</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094873.1">
        <property type="nucleotide sequence ID" value="XM_008096682.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJ15"/>
    <dbReference type="GeneID" id="24411362"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05997"/>
    <dbReference type="HOGENOM" id="CLU_1532424_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="147"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="67"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ30853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="175" mass="20501" checksum="FFC5A441BFF659DF" modified="2011-01-11" version="1">MNDPAVEKLKKQMDELLAEKAMREQQSMQEYIQKTTLEVAVQQTAEVVREVQGQAQLDIEIATVKAEIMAQEKAERSQREKKQIQDQTRLEVEREFALKLAQEKAMREELIETIREEFREKERRAMELEEIIQRIRHEAERKAYHVHSASSIGTPHPTARRPPPVSVFNMEPRAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJH6</accession>
    <name>E3QJH6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">LSM complex subunit LSM4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">LSM4</name>
        <name evidence="12" type="ORF">GLRG_06158</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Binds specifically to the 3'-terminal U-tract of U6 snRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">LSm subunits form a heteromer with a doughnut shape.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ31014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095034.1">
        <property type="nucleotide sequence ID" value="XM_008096843.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJH6"/>
    <dbReference type="STRING" id="645133.E3QJH6"/>
    <dbReference type="GeneID" id="24411523"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06158"/>
    <dbReference type="eggNOG" id="KOG3293">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099537_2_2_1"/>
    <dbReference type="OrthoDB" id="747253at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990726">
        <property type="term" value="C:Lsm1-7-Pat1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005732">
        <property type="term" value="C:sno(s)RNA-containing ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005688">
        <property type="term" value="C:U6 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017070">
        <property type="term" value="F:U6 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042149">
        <property type="term" value="P:cellular response to glucose starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000290">
        <property type="term" value="P:deadenylation-dependent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033962">
        <property type="term" value="P:P-body assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd01723">
        <property type="entry name" value="LSm4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000024">
        <property type="entry name" value="U6 snRNA-associated Sm-like protein LSm4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034101">
        <property type="entry name" value="Lsm4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027141">
        <property type="entry name" value="LSm4/Sm_D1/D3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23338">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="11">
        <location>
            <begin position="2"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="80"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="98"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="119"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ31014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="128" mass="13810" checksum="251B40366F3654EB" modified="2011-01-11" version="1">MLPLGLLNAAQGHPMLVELKNGETLNGHLVMCDTWMNLTLKEVVQTSPEGDKFVKIPEVYVKGNNIKYLRVPDDIIDVVKENQANHQQGGFRGGRGGNRGDHSGRGGDRGRGRGQGRGGRGRGNRGGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJP9</accession>
    <name>E3QJP9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_06231</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697353">
        <property type="protein sequence ID" value="EFQ31087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095107.1">
        <property type="nucleotide sequence ID" value="XM_008096916.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJP9"/>
    <dbReference type="STRING" id="645133.E3QJP9"/>
    <dbReference type="GeneID" id="24411596"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06231"/>
    <dbReference type="HOGENOM" id="CLU_2108842_0_0_1"/>
    <dbReference type="OrthoDB" id="74360at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050775">
        <property type="entry name" value="FAD-binding_Monooxygenases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43098">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43098:SF3">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ31087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="115" mass="12753" checksum="10BF0429D4DEA243" modified="2011-01-11" version="1">MHHSSFWPREGVDYVGKRVCMVGSVGTGSTEIQMSQEMSKQAAELTIFERALNMALLLPNQKLAADKQAARKEDYPGIYRARLESTGGYDFRAGAIGTIDHTPGQREANYSPFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJX8</accession>
    <name>E3QJX8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methylated-DNA--protein-cysteine methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.63</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">6-O-methylguanine-DNA methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">O-6-methylguanine-DNA-alkyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_06310</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 4-O-methyl-thymidine in DNA + L-cysteinyl-[protein] = a thymidine in DNA + S-methyl-L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:53428"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:10132"/>
            <dbReference type="Rhea" id="RHEA-COMP:13555"/>
            <dbReference type="Rhea" id="RHEA-COMP:13556"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:82612"/>
            <dbReference type="ChEBI" id="CHEBI:137386"/>
            <dbReference type="ChEBI" id="CHEBI:137387"/>
            <dbReference type="EC" id="2.1.1.63"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a 6-O-methyl-2'-deoxyguanosine in DNA + L-cysteinyl-[protein] = S-methyl-L-cysteinyl-[protein] + a 2'-deoxyguanosine in DNA</text>
            <dbReference type="Rhea" id="RHEA:24000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:10132"/>
            <dbReference type="Rhea" id="RHEA-COMP:11367"/>
            <dbReference type="Rhea" id="RHEA-COMP:11368"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:82612"/>
            <dbReference type="ChEBI" id="CHEBI:85445"/>
            <dbReference type="ChEBI" id="CHEBI:85448"/>
            <dbReference type="EC" id="2.1.1.63"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MGMT family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.63" evidence="3"/>
    <dbReference type="EMBL" id="GG697353">
        <property type="protein sequence ID" value="EFQ31166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095186.1">
        <property type="nucleotide sequence ID" value="XM_008096995.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJX8"/>
    <dbReference type="STRING" id="645133.E3QJX8"/>
    <dbReference type="GeneID" id="24411675"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06310"/>
    <dbReference type="eggNOG" id="ENOG502S8GR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_52_3_1"/>
    <dbReference type="OrthoDB" id="1907495at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003908">
        <property type="term" value="F:methylated-DNA-[protein]-cysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06445">
        <property type="entry name" value="ATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001497">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014048">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036217">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNAb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00589">
        <property type="entry name" value="ogt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10815">
        <property type="entry name" value="METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10815:SF13">
        <property type="entry name" value="METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01035">
        <property type="entry name" value="DNA_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46767">
        <property type="entry name" value="Methylated DNA-protein cysteine methyltransferase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00374">
        <property type="entry name" value="MGMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding" evidence="12">
        <location>
            <begin position="44"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ31166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="147" mass="15837" checksum="377C58778473CC82" modified="2011-01-11" version="1">MSTTALAKASSVTIVRDIASISVPEGDDMQTQLDRIARSNRTEYEKRVWTALCQVPKGQVTTYGILAAHLKSSPRAVGNALRRNPFAPQVPCHRVVATGGALGGFKGKWPKDGEGITVDEKRMLLRKEGVKIDSSGRVLGSPFVAYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>E3QK29</accession>
    <name>E3QK29_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Galactokinase</fullName>
            <ecNumber evidence="3">2.7.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Galactose kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">GLRG_06361</name>
    </gene>
    <organism evidence="20">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>alpha-D-galactose + ATP = alpha-D-galactose 1-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13553"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28061"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58336"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.6"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:13554"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GHMP kinase family. GalK subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.6" evidence="3"/>
    <dbReference type="EMBL" id="GG697354">
        <property type="protein sequence ID" value="EFQ31217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095237.1">
        <property type="nucleotide sequence ID" value="XM_008097046.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QK29"/>
    <dbReference type="STRING" id="645133.E3QK29"/>
    <dbReference type="GeneID" id="24411726"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06361"/>
    <dbReference type="eggNOG" id="KOG0631">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017814_6_2_1"/>
    <dbReference type="OrthoDB" id="187738at2759"/>
    <dbReference type="UniPathway" id="UPA00214"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004335">
        <property type="term" value="F:galactokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016126">
        <property type="term" value="P:sterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1440.340:FF:000003">
        <property type="entry name" value="GAL1p Galactokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000102">
        <property type="entry name" value="Similar to galactokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000705">
        <property type="entry name" value="Galactokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019741">
        <property type="entry name" value="Galactokinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019539">
        <property type="entry name" value="GalKase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006203">
        <property type="entry name" value="GHMP_knse_ATP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006206">
        <property type="entry name" value="Mevalonate/galactokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00131">
        <property type="entry name" value="gal_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10457:SF7">
        <property type="entry name" value="GALACTOKINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10457">
        <property type="entry name" value="MEVALONATE KINASE/GALACTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10509">
        <property type="entry name" value="GalKase_gal_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000530">
        <property type="entry name" value="Galactokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00473">
        <property type="entry name" value="GALCTOKINASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00959">
        <property type="entry name" value="MEVGALKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="GHMP Kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00106">
        <property type="entry name" value="GALACTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00627">
        <property type="entry name" value="GHMP_KINASES_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="10" id="KW-0299">Galactose metabolism</keyword>
    <keyword evidence="7 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="9" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="11" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Galactokinase N-terminal" evidence="18">
        <location>
            <begin position="33"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP kinase N-terminal" evidence="16">
        <location>
            <begin position="134"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP kinase C-terminal" evidence="17">
        <location>
            <begin position="425"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF10509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EFQ31217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="526" mass="56549" checksum="877495715CAC4F92" modified="2011-01-11" version="1">MAGPVPTATSLADIYTEDALPAQNKRWSSLLSQFQSEYGHAAAVVARSPGRVNIIGEHIDYSLYSVLPMAITADAILAFSVADTPADSETFTLRVANAQSDKYPSRTFEVPIAGDVPIDAEVHEWSNYFKSGLRGALELLRRKHGDGFRPKGMNILMDGTVPVGGGLSSSAAFVSASALAVMLANGEQKVDKTELTELAIVSERAVGVNSGGMDQSASVFSQRGSALFVSFTPSLTARPVFFPTTNPELSFLIAQSFVTSNKQVTGPIHYNLRVVECSMAGAYLNAALNPPGTNLPKDASPLGISLHGFHDAYFAHGKQPQADGASREEAAEAQLRELIDVTKNTLTKPEGYTREEIAGVLGVSAAELEAIFMSKLSVRAERFKLRQRALHVFEEALRVLQFMKVLEQEAPADTADTADYNARLGGLLNATQDSCRDLYECSAPEIDELCRIALENGSYGSRLTGAGWGGCTVHMVPANKVAAVKEAWEREYYSKRELTEEQKEGAVVVSRPGSGSAVYLLKEGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3QK83</accession>
    <name>E3QK83_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_06415</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697354">
        <property type="protein sequence ID" value="EFQ31271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095291.1">
        <property type="nucleotide sequence ID" value="XM_008097100.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QK83"/>
    <dbReference type="GeneID" id="24411780"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06415"/>
    <dbReference type="eggNOG" id="ENOG502T5FE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2108873_0_0_1"/>
    <dbReference type="OrthoDB" id="10313014at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ31271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="115" mass="13281" checksum="9574CF247BBC879B" modified="2011-01-11" version="1">MADVVLSNAVVSVQEDWLCDNSEFFRVCLRGGWKETITKAVHLEHVDAQTFLLLVEAMEVVLNSPDIKIRHHFEKASDRVISFLPDSQPITAFSRLVRLADFLLMTNLYFFLRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKA9</accession>
    <name>E3QKA9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DnaJ domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_06441</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697354">
        <property type="protein sequence ID" value="EFQ31297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095317.1">
        <property type="nucleotide sequence ID" value="XM_008097126.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKA9"/>
    <dbReference type="STRING" id="645133.E3QKA9"/>
    <dbReference type="GeneID" id="24411806"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06441"/>
    <dbReference type="eggNOG" id="KOG0714">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073129_3_0_1"/>
    <dbReference type="OrthoDB" id="442087at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050817">
        <property type="entry name" value="DjlA_DnaK_co-chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24074">
        <property type="entry name" value="CO-CHAPERONE PROTEIN DJLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="9"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ31297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="243" mass="26256" checksum="775CAE99ED558368" modified="2011-01-11" version="1">MANAGAPPDYYKILEIAETATTQQVRDAYKKAALKTHPDRVPADSPERATRTRKFQLVNDAYYTLSDTQRRREYDAQRKLFGASAGATYGDFSDDDDPAEEVPPQQTGSGGGGGKSQSAYSWAWNFFTGGKQSEEERERTGNQQFGDVFEEMLREEGMAEEGTNRPTGSFWGTIGGLSGGALGFIVGNMPGAVAGAVAGNRLGAVRDARGKSVYAVFQELPQPDRARLLTQLAAKIFSHTVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKS4</accession>
    <name>E3QKS4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Capsule polysaccharide biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_06606</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the lcsJ thioesterase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697355">
        <property type="protein sequence ID" value="EFQ31462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095482.1">
        <property type="nucleotide sequence ID" value="XM_008097291.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKS4"/>
    <dbReference type="GeneID" id="24411971"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06606"/>
    <dbReference type="eggNOG" id="KOG4366">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040660_0_1_1"/>
    <dbReference type="OrthoDB" id="265761at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051490">
        <property type="entry name" value="THEM6_lcsJ_thioesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12475">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12475:SF4">
        <property type="entry name" value="PROTEIN THEM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ31462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="184" mass="20556" checksum="EA8856F776762A2B" modified="2011-01-11" version="1">MLGAVHCSFRREITAYAPYEMWSRVLSWDRKWLYIVTHFVPKGTARPTEWLDPKFGTARVRRGPGAPGTTDSKEWEKKIYATGVSKYVFKIGRLTVHPAVALEESELLPHRPDGGWQGGPNGVGDEDLDLSDVADDGAWDWRMVEKRRREGMKYAARFASMDDLHGWLDGADGGDGSALAKFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKU1</accession>
    <name>E3QKU1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA-directed RNA polymerase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_06623</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697355">
        <property type="protein sequence ID" value="EFQ31479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095499.1">
        <property type="nucleotide sequence ID" value="XM_008097308.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKU1"/>
    <dbReference type="STRING" id="645133.E3QKU1"/>
    <dbReference type="GeneID" id="24411988"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06623"/>
    <dbReference type="eggNOG" id="KOG4134">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036411_2_1_1"/>
    <dbReference type="OrthoDB" id="10250504at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006362">
        <property type="term" value="P:transcription elongation by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04328">
        <property type="entry name" value="RNAP_I_Rpa43_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.1060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.120">
        <property type="entry name" value="RNA polymerase Rpb7-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036898">
        <property type="entry name" value="RNA_pol_Rpb7-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041901">
        <property type="entry name" value="RNAP_I_Rpa43_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041178">
        <property type="entry name" value="RPA43_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045113">
        <property type="entry name" value="Rpb7-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709:SF5">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II, III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17875">
        <property type="entry name" value="RPA43_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RPA43 OB" evidence="7">
        <location>
            <begin position="290"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="418"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="469"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="14"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="80"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="103"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="420"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU369086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ31479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="502" mass="54836" checksum="F7AB32F8A17EB299" modified="2011-01-11" version="1">MAAIVSPVTNGHKSDKKSKKDKKEKKRLREEEDAEAAEERKHKRTKSTVVVPDDDESPSGSQDLSLAPSAATNGEPSPEKKKKKDKKHKKSVGEAEEEGAASDAERKEQKDKKDKKKKRKPQKETEDDLEEPSIETTAAAAPASEKKEKKSKKAKTASPEPAADDKDDAMDVDSPARTKSTSRVHQPPDAPSKPQFPFFTQTVSLYLPIYPVGWDTPCTAAASQHLEPLVNRYVPELKGVLLAFRNVSLSEQPGRRHAATNDSEHCDLVSVDEYAVGFGYVTVDVDLFVPRRGAWMEGSINLESEGHIGVVCWGKFNASIESSRLPPEWRWVHAGSAEAASYVADPFDGDDAAAAEAEAEDEHGAVRQIHTTGFWVDGNGDKVKGRVRFRVKAFDVGVSGDHGYLSLEGTMLDAAGEKAATQRDAEQERRRRAGKSGVGAAAGILAKERRRMPEFSVTKFGAVEDEEDKALRKDVWDTTEPATESNEAGEKEAFAGISTEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKZ8</accession>
    <name>E3QKZ8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_06825</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697356">
        <property type="protein sequence ID" value="EFQ31536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095556.1">
        <property type="nucleotide sequence ID" value="XM_008097365.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKZ8"/>
    <dbReference type="GeneID" id="24412190"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06825"/>
    <dbReference type="eggNOG" id="ENOG502RFJG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108562_0_0_1"/>
    <dbReference type="OrthoDB" id="4799298at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="63"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ31536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="157" mass="16855" checksum="6892FA7D4F401641" modified="2011-01-11" version="1">MSLNPSFPTDRFGPGFTVPSAVTVTEGGRTITLTPTPEPQPTSEGTPFPDNILQQSGLAPGQIIGITLGATSSLVLFVVALVWFWNRRRARAQAARDEALDTVMDDPEKPDEATLMGTNNGETTELPAPRGLHEMPETREGPAVELPAPVERHEMPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QL45</accession>
    <name>E3QL45_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_06872</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697356">
        <property type="protein sequence ID" value="EFQ31583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095603.1">
        <property type="nucleotide sequence ID" value="XM_008097412.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QL45"/>
    <dbReference type="STRING" id="645133.E3QL45"/>
    <dbReference type="GeneID" id="24412237"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06872"/>
    <dbReference type="HOGENOM" id="CLU_2223086_0_0_1"/>
    <dbReference type="OrthoDB" id="4847895at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="106" mass="11634" checksum="7CD47480BAB4081E" modified="2011-01-11" version="1">MLAASRVSPTAKIPRIAGHERGAAAGIELQELIPASDKGYGESVNSNAHKNMAYRLLKWGEVEMPEDWHRESAEEGNDQEAPRVGHLSFGTILDDPQPPTEGYFYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QL71</accession>
    <name>E3QL71_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">BTB/POZ domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_06898</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697356">
        <property type="protein sequence ID" value="EFQ31609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095629.1">
        <property type="nucleotide sequence ID" value="XM_008097438.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QL71"/>
    <dbReference type="STRING" id="645133.E3QL71"/>
    <dbReference type="GeneID" id="24412263"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06898"/>
    <dbReference type="eggNOG" id="ENOG502QRM9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017395_0_1_1"/>
    <dbReference type="OrthoDB" id="2414723at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31758">
        <property type="entry name" value="BTB/POZ DOMAIN-CONTAINING PROTEIN YLR108C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31758:SF2">
        <property type="entry name" value="BTB_POZ DOMAIN-CONTAINING PROTEIN YLR108C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="412"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="511" mass="56213" checksum="7B733E48BB14F182" modified="2011-01-11" version="1">MSAAPANNNANPKPPSSSSALRDEAQVVKIPHILPHERVFPIQIGNELFKLSGASISSDAPSYFSQYFYCQVKKAHETGEDLSNAIRTLYIDRDPQTFADISLHLQGYHVKPRDGTHFVRLFADAQFYSLPKLISQLYEESIFISIGHREFQIPRDIFTDPGNSPNFFSLGFAVFFSNPEDLFPGLDREGLLRPPSILPPSVPNRSAETFAEILHLLRGYPVTIRGETHRAELLRDCRYFNFKGLEQKLIPHHISYNQSRRREEIVLRLEDILKSGISVAADVSASPGDHLSGWVNYARPYVDDRAAELVLEVGGESTRIHFQSGSARAEFFRDTRARIARLFEVVATKLNLPPTTQPLGLLMASGGAGSQPPTPGHTPLSEDLVRVSIDADTSVTLDGKPYVLEADDLHPANQPMSAASSTAGGLESPTAPSSFQPNSRKRRRIDSLGYVAAGQAALAADEWVVRTGQWRLKIQGSRGGKSSVEVVLVAVKLDAYSSENARNAARGFLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLT3</accession>
    <name>E3QLT3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ubiquinone biosynthesis protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_06796</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Membrane-associated protein that warps the membrane surface to access and bind aromatic isoprenes with high specificity, including ubiquinone (CoQ) isoprene intermediates and presents them directly to Coq7, therefore facilitating the Coq7-mediated hydroxylase step. Participates in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the COQ9 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697357">
        <property type="protein sequence ID" value="EFQ31821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095841.1">
        <property type="nucleotide sequence ID" value="XM_008097650.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLT3"/>
    <dbReference type="STRING" id="645133.E3QLT3"/>
    <dbReference type="GeneID" id="24412161"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06796"/>
    <dbReference type="eggNOG" id="KOG2969">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057411_1_1_1"/>
    <dbReference type="OrthoDB" id="619536at2759"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.357.10:FF:000004">
        <property type="entry name" value="Ubiquinone biosynthesis protein COQ9, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.10">
        <property type="entry name" value="Tetracycline Repressor, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013718">
        <property type="entry name" value="COQ9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048674">
        <property type="entry name" value="COQ9_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012762">
        <property type="entry name" value="Ubiq_biosynth_COQ9"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02396">
        <property type="entry name" value="diverge_rpsU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21427">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS PROTEIN COQ9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21427:SF19">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS PROTEIN COQ9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08511">
        <property type="entry name" value="COQ9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21392">
        <property type="entry name" value="COQ9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="7 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4 8" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="domain" description="Ubiquinone biosynthesis protein COQ9 HTH" evidence="10">
        <location>
            <begin position="51"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="COQ9 C-terminal" evidence="9">
        <location>
            <begin position="157"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF21392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ31821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="256" mass="28505" checksum="C76A9F82B11FFE99" modified="2011-01-11" version="1">MSHLCRPATRAALRSLRQCPSAAFAGPRTTRSYQSYDHPDSTTYFHPQEKTILSAAYKHVPEHGFSHKALALGAKDTGYLDISTSVLSDGPFNLIRHHLVERREGLAVKSKEILGEGSQFDIDEKVERLTWQRLLENATIIDRWQEALAIMAQPSYAPASIKELAKLVDEIWFLSGDVSVDASWYTKRASLSMIYASSELFMTNDKSAGFRDTKDFLRRRLNEVKGAGDVLGSVGQWVGFTASAGVNVLRSKGLRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLX7</accession>
    <name>E3QLX7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">GPI mannosyltransferase 1</fullName>
            <ecNumber evidence="13">2.4.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">GPI mannosyltransferase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_07009</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly. Required for cell wall integrity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Endoplasmic reticulum membrane</location>
            <topology evidence="1 13">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the PIGM family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="13"/>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095885.1">
        <property type="nucleotide sequence ID" value="XM_008097694.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLX7"/>
    <dbReference type="STRING" id="645133.E3QLX7"/>
    <dbReference type="GeneID" id="24412374"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07009"/>
    <dbReference type="eggNOG" id="KOG3893">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024220_1_0_1"/>
    <dbReference type="OrthoDB" id="1741594at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990529">
        <property type="term" value="C:glycosylphosphatidylinositol-mannosyltransferase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051751">
        <property type="term" value="F:alpha-1,4-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004376">
        <property type="term" value="F:GPI mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007704">
        <property type="entry name" value="PIG-M"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12886:SF0">
        <property type="entry name" value="GPI MANNOSYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12886">
        <property type="entry name" value="PIG-M MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05007">
        <property type="entry name" value="Mannosyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 13 14" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5 13" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="80"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="125"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="161"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="284"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="314"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="380"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU365064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ31865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="421" mass="47039" checksum="A93198D5B5DF8137" modified="2011-01-11" version="1">MAGLDALFRPVPLFATAAVLRVVMLYYGLWQDAYSAVKYTDIDYLVFTDAARFTAQGRSPYDRETYRYTPLLAWMLVPTASQACFAFGKFVFAAADLIAGYYIVRILDRRGVEQAKALKFASIWLLNPMVATISTRGSSEGLLGVTVMALLWAVLEGRTTLAGLLLGFGVHFKIYPFIYAPAIVWWMDEDALGRKGTNAHGKTLGETIANFLNTERIKLAVVSLATFMGLNVAMYSIYGAPFLVHTYFHHVTRIDHRHNFSPYNILLYLTSAFPSTSAIRIESVAFLPQILLSTILIPFILAKKDLATSMMAQTFAFVTFNKVCTSQYFLWYMVFLPIYLPNSSFLKNPKLGVTALALWIVSQAAWLHQGFQLEFLGVSTFFPGLFAASVGFFLVNCWILGVIVNDGGKETATHTKRKIKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3QM04</accession>
    <name>E3QM04_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">WD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_07036</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095912.1">
        <property type="nucleotide sequence ID" value="XM_008097721.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QM04"/>
    <dbReference type="STRING" id="645133.E3QM04"/>
    <dbReference type="GeneID" id="24412401"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07036"/>
    <dbReference type="eggNOG" id="KOG0282">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022571_0_1_1"/>
    <dbReference type="OrthoDB" id="10257301at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
        <property type="term" value="C:nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000386">
        <property type="term" value="F:second spliceosomal transesterification activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000350">
        <property type="term" value="P:generation of catalytic spliceosome for second transesterification step"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000389">
        <property type="term" value="P:mRNA 3'-splice site recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000348">
        <property type="term" value="P:mRNA branch site recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="mRNA splicing factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024977">
        <property type="entry name" value="Apc4-like_WD40_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032847">
        <property type="entry name" value="PRPF17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43979">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43979:SF1">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12894">
        <property type="entry name" value="ANAPC4_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="223"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="267"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="354"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 4-like WD40" evidence="4">
        <location>
            <begin position="416"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="486"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ31892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="519" mass="58616" checksum="405924E82E09DF5D" modified="2011-01-11" version="1">MAPQDALVVRQEAEPDHAVVPYTGEDLARPKLGPANPFKDEATTLKRKNVLTGTAEETYISEHTFRSKHRAIERKGGPEREYQTGASVKEQNARIRSAREKKGDATIVEGDGAYVGPWARYKREEYEIVREGEELASDEEYEEVTDEDDVVESGTVLRAPEAALARRKEVEEMGEETTTFHGAEERDYQGRTYMHVPLDLDVDLRKEPGSVTNFIPKKQIHTWRDHSKAVTALRFFPGSGHLLLSASADSTVKIWDVYHNRELLRTYSGHAKAVSDATFNNSGTQFLSASFDRQIKLWDTETGTCLSRFSTGKTPHVVRFNPSAEHAHEFVAGMSDKKIVQWDTRAGNEIVQEYDHHLAAINTITFVDEGRRFMTTSDDKSLRAWDYNIPVPIKYIAEPYMYPMTRAAPHPSGKYVAFQSSDNQIVVYGANDKFRQNRKKSYRGHNNAGTAIDVSVSPDGQFLASGDTQGFVCFWDWKTCKMYHKLKAGDQPVTCVAWHPQETSKFVSAGAEGDIRYWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QM65</accession>
    <name>E3QM65_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Helix-turn-helix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_07097</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095973.1">
        <property type="nucleotide sequence ID" value="XM_008097782.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QM65"/>
    <dbReference type="STRING" id="645133.E3QM65"/>
    <dbReference type="GeneID" id="24412462"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07097"/>
    <dbReference type="eggNOG" id="ENOG502SEWH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087328_1_0_1"/>
    <dbReference type="OrthoDB" id="4085451at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054448">
        <property type="entry name" value="HTH_put_ascomycetes"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22943">
        <property type="entry name" value="HTH_68"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helix-turn-helix" evidence="2">
        <location>
            <begin position="150"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ31953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="195" mass="20384" checksum="3B7243434F317665" modified="2011-01-11" version="1">MGSSSSKAAQGAARKFPTRAPGAVPPISAAGRAAPAPSPSQPAQARPQAKAATLKTGDIAADSVNPDSVTAEFSSRLRQMGIVQPNPTFSPTSTAGPSPHADLIQNPGPLFPSSSRNATLGTLEARSRFQKQADDEFDGLGRSSSEGREFLDLKTIVQMHLMRDKGHSHAEIEKRLNLKKGVVARLGRPGITSPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMP4</accession>
    <name>E3QMP4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Putative peptidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_07276</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the ZPS1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096152.1">
        <property type="nucleotide sequence ID" value="XM_008097961.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMP4"/>
    <dbReference type="STRING" id="645133.E3QMP4"/>
    <dbReference type="GeneID" id="24412641"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07276"/>
    <dbReference type="eggNOG" id="ENOG502RTN8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048223_0_0_1"/>
    <dbReference type="OrthoDB" id="4689212at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005178">
        <property type="term" value="F:integrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11307">
        <property type="entry name" value="M35_Asp_f2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.390.10:FF:000043">
        <property type="entry name" value="Major allergen Asp F2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029482">
        <property type="entry name" value="HRXXH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039124">
        <property type="entry name" value="PRA1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39399">
        <property type="entry name" value="PROTEIN ZPS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39399:SF1">
        <property type="entry name" value="PROTEIN ZPS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13933">
        <property type="entry name" value="HRXXH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178636" description="Putative peptidase domain-containing protein" evidence="5">
        <location>
            <begin position="19"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Putative peptidase" evidence="6">
        <location>
            <begin position="35"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="256"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="258"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00060890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ32132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="304" mass="32497" checksum="491053130989E9F7" modified="2011-01-11" version="1">MMYGVATAALLLSALADATPLARRQAPETAPASVPSAVAAPTSQAPPYDWSAGWQRAFPIHQSCNSTLRAQLEAALAETQQLAAHARDHILRFGNSSEHVRKYFGDAPTATPAGWYDRVVNADKAGMTFRCDDPDRNCATQDGWAGHWRGANATQETVICPLSFEVRRPLSSVCGLGYTVAGSKLNTYWATDLLHRVLHVPLIAEGVVEHYAEDYTEALALAENNATYAVVDSNALQYFAIDVWAYDIAAPGVGCSGELEEEEEEEEKPAPTTTAIGSAATTPAATSSAPQECHTHADGVLHCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMV0</accession>
    <name>E3QMV0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="15">UBA/TS-N domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">GLRG_07332</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the PAN1 actin cytoskeleton-regulatory complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Actin patch</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697360">
        <property type="protein sequence ID" value="EFQ32188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096208.1">
        <property type="nucleotide sequence ID" value="XM_008098017.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMV0"/>
    <dbReference type="STRING" id="645133.E3QMV0"/>
    <dbReference type="GeneID" id="24412697"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07332"/>
    <dbReference type="eggNOG" id="KOG0998">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002006_0_0_1"/>
    <dbReference type="OrthoDB" id="524326at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00052">
        <property type="entry name" value="EH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000261">
        <property type="entry name" value="EH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216:SF170">
        <property type="entry name" value="DYNAMIN ASSOCIATED PROTEIN 160, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216">
        <property type="entry name" value="EH DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12763">
        <property type="entry name" value="EH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00027">
        <property type="entry name" value="EH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50031">
        <property type="entry name" value="EH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EH" evidence="13">
        <location>
            <begin position="19"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="EH" evidence="13">
        <location>
            <begin position="146"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="14">
        <location>
            <begin position="293"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="EH" evidence="13">
        <location>
            <begin position="294"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="12">
        <location>
            <begin position="1189"/>
            <end position="1229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="369"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="530"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="665"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="693"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="935"/>
            <end position="1199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="385"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="399"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="437"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="454"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="698"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="758"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="778"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="830"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="871"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="936"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1018"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1057"/>
            <end position="1066"/>
        </location>
    </feature>
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        <location>
            <begin position="1125"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1153"/>
            <end position="1164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EFQ32188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1230" mass="128722" checksum="94773A9C9141FBD8" modified="2011-01-11" version="1">MSAEGVDAAAPNLNLTPEEKRLYGQLFRQADTESVGVVTGETAVKFFEKTRLDSRVLGEIWQIADKENRGFLTPAGFGLVLRLIGHAQAGREPTTEIALQPGPLPRFDSMPPPAGLTSPTAPPAVPLQAQSTGGGPIRIPPLTPEKVSQYAGLFERQPLQAGNLLPGDAAKSIFEKSGLPTEVLGRIWQLADTEQRGALVLTEFVIAMHLLTSMKTGALRGLPNILPAALYEAATRRGPTAPRQSPTGTGPISAIPRQLSGSAQFRAGSPLGRPPITAQTTGTPASDWLITPDDKARFDVLYNDLDKTHKGFITGEEAVPFLSQSNLPEDALAQIWDLADINSEGRLNRDTFAVAMYLIRQQRMRRDGSVSLPTTVPANLIPPSMRTQARPQTSGSPFDAPPQPQPPAPAPPPAPKSALDDLFGLDTPPAPAPAQVALSTGGSNANDPFGSGSAVLTPSSPIRPSPTGTQFKPFVPSSSFGRGLTVHSTGDSNSGKPPAPSASEDLLGDGDPEVSKKLTNETAELANLSNQVGSLSKQMQEVQGQRTTTQNELNQANSQKKNFEQRLAQLRTLYEKEAKDVEALQVQLNTSRNETKKLQAECMALDGTYRDLQTQHQQVYLGLQADQAENAKLKETIRTLNAEIAKLKSQTEKLRSEARQQKGLVAINKKQSATNEGERDKLQTELSDLSKNNEELSRQANTSSPIASSAQVASPTPSTASGNNPFFRRTGSTDIMGSFGSPPPVKPSSVDKSFDDVFGPAFPPAGSSSTPPPATSFKPQHTGASTASLGSFSTPPVPTSPNVSRQATLTAEPPAPPESRQISSSFLPFADASESLSSSRAVSPPASRAEGSETPQANSLPGAFPLEVAATGQSTDSASTASNKEPAVQGDTKPSGNGVAVAPNKAAVDSDPFAAMGSNDAKADFDDAFASFTSAHKSSVGSGADANKSSSAFDSEFPPISELDREDDDSDTASEGGGFGGGFDDDFAPASPQAKKTEAPEEDKEATSPPPAPVVEDVSASEPTAAVAASSEVSETPVAPAASAAQPAAPKAKSSFDDLDDEFEGLEDAKEGSADDDFQTISRSGLDDFNPVFDSSPPPSQAKTESTAFGHESSYDFGSVSPNPAAGGNAGASAKGTGASEAQDWDAIFASLDSPSDANANPTASAPALVPPATETRPAPGRALTQSSEHDDPILKNLTSMGYSREDAILALEKYDYNLERAANYLASQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMV9</accession>
    <name>E3QMV9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ATP synthase subunit 5, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_07341</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase delta chain family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697360">
        <property type="protein sequence ID" value="EFQ32197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096217.1">
        <property type="nucleotide sequence ID" value="XM_008098026.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMV9"/>
    <dbReference type="STRING" id="645133.E3QMV9"/>
    <dbReference type="GeneID" id="24412706"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07341"/>
    <dbReference type="eggNOG" id="KOG1662">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085114_0_0_1"/>
    <dbReference type="OrthoDB" id="1262810at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.20">
        <property type="entry name" value="N-terminal domain of the delta subunit of the F1F0-ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01416">
        <property type="entry name" value="ATP_synth_delta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026015">
        <property type="entry name" value="ATP_synth_OSCP/delta_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020781">
        <property type="entry name" value="ATPase_OSCP/d_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000711">
        <property type="entry name" value="ATPase_OSCP/dsu"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01145">
        <property type="entry name" value="ATP_synt_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11910">
        <property type="entry name" value="ATP SYNTHASE DELTA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00213">
        <property type="entry name" value="OSCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00125">
        <property type="entry name" value="ATPASEDELTA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47928">
        <property type="entry name" value="N-terminal domain of the delta subunit of the F1F0-ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00389">
        <property type="entry name" value="ATPASE_DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ32197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="233" mass="24208" checksum="92B3922C45F5FBAF" modified="2011-01-11" version="1">MFSRQAVRSLRAAAPASRLVASARVPAVRTYAAAASSAASDNVKPPVAVFGLDGTYATALYTAATKSSSLDPTAKALSTLEAIFAKDPKLATVLAAPTLTPEDKDAIVAELTKQAGATSQQTVKNFLAALAENNRLGLLPGITQKFAEIMSAARGEVELVVTSATQLDNRTLNRLESAISKSAYAGAGKKLKVTNQVNPDIIGGLIVEIGDRTIDLSVSAKIAKLNKLLTDTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QN71</accession>
    <name>E3QN71_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_07453</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. TCR/Tet family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697361">
        <property type="protein sequence ID" value="EFQ32309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096329.1">
        <property type="nucleotide sequence ID" value="XM_008098138.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QN71"/>
    <dbReference type="GeneID" id="24412818"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07453"/>
    <dbReference type="HOGENOM" id="CLU_2687683_0_0_1"/>
    <dbReference type="OrthoDB" id="10021397at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF102">
        <property type="entry name" value="DRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G08530)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ32309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="74" mass="7757" checksum="CC52E349B7DDD193" modified="2011-01-11" version="1">MSTALRLVVVMNIPLLLFGRAVHGLGAAGLITLVNICICDLFSLRGRGLYFGLRSIVWALASGLGPVLGGVFTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNA6</accession>
    <name>E3QNA6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07488</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697361">
        <property type="protein sequence ID" value="EFQ32344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096364.1">
        <property type="nucleotide sequence ID" value="XM_008098173.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNA6"/>
    <dbReference type="STRING" id="645133.E3QNA6"/>
    <dbReference type="GeneID" id="24412853"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07488"/>
    <dbReference type="eggNOG" id="ENOG502QPMX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012880_0_0_1"/>
    <dbReference type="OrthoDB" id="5408998at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="500"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="48"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="389"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="440"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="530"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="548"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="568"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="611"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="629"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="685"/>
            <end position="694"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="743" mass="79042" checksum="01A03024CDE4D1D4" modified="2011-01-11" version="1">MRETEADMDDVPPPPYSETDIYSVSGRHSNPSLNSPIAQSHHGDDAASHVSSHTSSRSDVIYTPPLTPRTGSTAAPQHHNSNPNLANHAHAAAADPSVASAQSIFAAAYFESRPAPAFSPWDQQLVNLLTVTPSSTPDDLPCPPTWAARDVTQQDWATFTNCLIPHHAVARNEAVINRKLQAEEEAVAAAASHGGSGDNSPGGPRSISSSHASAQLDRIRPDPDTDPGAAVAASGPRREDVEAVVAQWNEGFFHPRGLAVLLTPEVEELRLPGAWDRSLDRSIDNPTVPSGSWSGGATPMPPPGPHAGTGQGPSEARGGWSFGGITVTTDGISIGDSIVADSNGIRLGNLIADENGIRFGSNTIPRAQPHFVGPNVNWAPPPPHAPSVPSPVPMFGPRPGPGPGPFPPRPHPHNHAHARPGSGSGFRGRPHGRYPSDQRSISASSSASSVSSTSSTSSVGSLPDYEDLCPAQLPVYKQRVAAWLAHPDEPVTKTDVAQLCDEIRSAQSASGAPEKPKQDDPSVADTPEGADDKAFKAELKGLTQEWRKLKRQQRAVRKDKRRERRARRREEKKERREQRRERREQRRDGRWDQKETRRGASGEGDGAARGNHQHHHHHHHHHGPKPKPKLAPPPPPPHIHVPPPPVMHAQPIPAVPILSPNDSNNFQWGAGPGRGPVPPGGFSVGRGAWAAAFGRGWGRGRGAGNDHAFPPNAGPPHPHGAWPAGGSGKRGPDTAMPPVPPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNI7</accession>
    <name>E3QNI7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase</fullName>
            <ecNumber evidence="4 13">4.2.1.134</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_07744</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16 13">
            <text>a very-long-chain (3R)-3-hydroxyacyl-CoA = a very-long-chain (2E)-enoyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:45812"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:83728"/>
            <dbReference type="ChEBI" id="CHEBI:85440"/>
            <dbReference type="EC" id="4.2.1.134"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Endoplasmic reticulum membrane</location>
            <topology evidence="13">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the very long-chain fatty acids dehydratase HACD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.134" evidence="4 13"/>
    <dbReference type="EMBL" id="GG697362">
        <property type="protein sequence ID" value="EFQ32474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096494.1">
        <property type="nucleotide sequence ID" value="XM_008098303.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNI7"/>
    <dbReference type="STRING" id="645133.E3QNI7"/>
    <dbReference type="GeneID" id="24413109"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07744"/>
    <dbReference type="eggNOG" id="KOG3187">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034302_6_1_1"/>
    <dbReference type="OrthoDB" id="46988at2759"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102158">
        <property type="term" value="F:very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030497">
        <property type="term" value="P:fatty acid elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007482">
        <property type="entry name" value="Tyr_Pase-like_PTPLA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11035">
        <property type="entry name" value="VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11035:SF24">
        <property type="entry name" value="VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04387">
        <property type="entry name" value="PTPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11 13" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="7 13" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5 13" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9 13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="14"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU363109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ32474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="216" mass="23547" checksum="ED6435BCBB5B7079" modified="2011-01-11" version="1">MAAKGQRAESGVRVAYLTLYNAIFASLWASVLFTVAATMSAGGGGGAPAVYEAAEARSRWVQTLTLIEVVHSALGLVRSPVGTTALQVVARTIIVWMVCYSFPATTASSAAYVSLLLSWAAADTVRYAYLALNLHGKAPAALVWLRYTMFYPLYPVGIASEFWLLYLAVEPARRVSAALPPVFYFCLCLYVPGSYVMYTYMIKQRRKTLSKLGKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPF0</accession>
    <name>E3QPF0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cell agglutination protein mam3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_07882</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697364">
        <property type="protein sequence ID" value="EFQ32738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096758.1">
        <property type="nucleotide sequence ID" value="XM_008098567.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QPF0"/>
    <dbReference type="GeneID" id="24413247"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07882"/>
    <dbReference type="eggNOG" id="ENOG502QQXP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_272251_0_0_1"/>
    <dbReference type="OrthoDB" id="4405280at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180791" description="Cell agglutination protein mam3" evidence="2">
        <location>
            <begin position="21"/>
            <end position="1332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="823"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="823"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="858"/>
            <end position="869"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ32738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1332" mass="135946" checksum="E4A8DDC58A20326B" modified="2011-01-11" version="1">MPEPWKLILASLLLGGKSAAQSCIDALNNNRTDACVCYSLEYVVSYVAYIAVSTSYTSSCEALPTTTSAGLSIGLQVLDRISAGDFAGYVTQNNGVYTGTGIIAGPTTVDIIPPSGTAPGTLVVEVPPSYFTISRTGTATVSPEPVPTYVDSTSFLTRNIISDPRTIRLINPTPDAAAASRGTVVIAVPDPRLFRTAEVAYSGTEVLTAARTTISTIPDNGLVPGTFIVAVATTPLPNLSYDISTVAYTGTAALTTPTVISVIQPTGTGAGVVVLAVPLSGVPPPRLTSIIPYTGTETITTALTILDRPFDGTLPGALVIALPSSSFITETVTLTGTEVLTAPTVISVIPPSGSGLGRVIVGSPLASYVASYVSYTGSVAITSQTTVSVIRPSGTVAGTVIIAEAPQALTIVSEVYRTQLVTYTASDAIVGPTALSTIAPESSRPDDILVALPASYQKEAATPFFTSIVLYTGSNAINGPSTLNVISPSGTEAGTVIIGLPRLTPPAGAGSGSFITSAVPVSYVTVTVVAYDDVQLVTLTSILPSGTSPGTVFIGPSPTVGGLPVVFVTQVIPYTGSTPITEPTTLSIIPPSNSALGTIIVADPRSFVRTTVPYVGTEPLTQVTTIAVVPPENDQPGLVVVAVPSATPVGPSYVTSYVTYLGTSIQQPTTISIVQPTGTTPGTLIVARPAEFVTSTVPYTGSATLPTPTTIAIVPPTGTEPGIIYVADPTAFVTSTVEFTEIGSFTESNTVTVIPPSGNRQGTVVVAGLRPFITSYVQLSGTSPAEGPTTLTLVQPQGTAPGTVIIGVPSSFQISTVVNSETRVLTTSPTTRSTGSPVAARPGRINVALQRPSPQTNSPAESSPGSAGPVATAGSPAALVQSFVTSTVLYSGTAISSDQSTLSTVQPSGTAPGTYIVGITDLFVTSQVVYTGTRSLTGPVPIFTVQPSASNPGTVIFAVPASYVTSEVQYTGPVGQLTTPSPITTIPPSGGVPGTVIVARPGQYVTSEITLTELADPRITTPSIVSTIPPSGTEPGTVIVARPFQYVTSDVFYTDPAGPQITAPSTVTIVPPSGTQPGVVIVARPPQYVTSEIVYTELSGQQVTAPRIVSTIPPNGTQPGVVIVARPPQYVTSEIVYTELSGQQVTAPRIVSTIPPNGTQPGIVIVARPPQYVTSEVFYTDPASPQITAPSTVTIVPPSGTQSGVIIIAQPPNYQTSEVFLTGINGPTTLSTIPPSGTVSGTFIVARPVASVTSEANIPGVTSSSTILPIPSSDTPLAVIVGQPAALSTSAVALTSPAASIVTGKVILTTIVTSGTEPGLFYLIRYFTRGWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPP3</accession>
    <name>E3QPP3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_07964</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697365">
        <property type="protein sequence ID" value="EFQ32820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096840.1">
        <property type="nucleotide sequence ID" value="XM_008098649.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPP3"/>
    <dbReference type="GeneID" id="24413329"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07964"/>
    <dbReference type="eggNOG" id="ENOG502S0VB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068952_0_0_1"/>
    <dbReference type="OrthoDB" id="3926209at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843:SF3">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="68"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ32820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="288" mass="31609" checksum="F4D5F9A9B3605096" modified="2011-01-11" version="1">MADFANDAEVSSDAPANPAVDVEMEGAEAAEAVETADNVDVENLPFAEGGESDPVEPRTTFVDYLSSPVVTLLVGQGETETIVTAHQALLTQSPYFKEACAQFSDDGSPRQIELAGEEIDAVGCFLEFLYTGEYFPRKVAGTRTLESDPAVPEVDTDGTQLLKHARVYTLADKFGMPNLRSLASSKIHCVNSTAKGEIAYARYVYAYTSKDDTTIRAPVASFWATRSHTLRSEAEEEFRSLCLEHPQFGYDVLTRVLDEKLKRERNDKLHPSTSSTGSARKRARHSQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQ13</accession>
    <name>E3QQ13_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_08095</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697366">
        <property type="protein sequence ID" value="EFQ32951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096971.1">
        <property type="nucleotide sequence ID" value="XM_008098780.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQ13"/>
    <dbReference type="GeneID" id="24413460"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08095"/>
    <dbReference type="HOGENOM" id="CLU_2654348_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ32951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="76" mass="8626" checksum="E04CDDA513A49951" modified="2011-01-11" version="1">MTSIDEEDLRGRATTARAHPLWIPPPLLFTLTFRCRALHSSTGMVIQGKRGRVALFRHRTAGKTSVETTRYGRTWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQX5</accession>
    <name>E3QQX5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Heat shock protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_08407</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697369">
        <property type="protein sequence ID" value="EFQ33263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097283.1">
        <property type="nucleotide sequence ID" value="XM_008099092.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQX5"/>
    <dbReference type="STRING" id="645133.E3QQX5"/>
    <dbReference type="GeneID" id="24413772"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08407"/>
    <dbReference type="eggNOG" id="KOG2655">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018628_0_0_1"/>
    <dbReference type="OrthoDB" id="4150765at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0346">Stress response</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ33263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="450" mass="49050" checksum="8EFC356A591C28F6" modified="2011-01-11" version="1">MSAFGASDHGKPQSAYSGEAAQQFIMPTINVPSRRPFTETGKSLGRLKILLAGRSGLGKTALIRAITQSCSHIVHVDPTMPVAMASAGLLPANTLPNDPPIVQGTFQITETFASTKPYPPWWKESVQTSCVSGTGSVDDTILERNICLVDTPGYQETCRPVDTVGQVSQYVESHLQKNRLDGLEDPDVLKTIGGSGGLLVDAVLYTIPSSAEAGLRLFTFAPTTPNAQAPDIYAISSELGSDHDVMDASLLMSSDVDGATWLRHAAATKLLGWRLRRPKTSNSSAGLSLQTDGCTERRLLRTRTGPLTPLTMSCVPNYARYEERFCRVQLSDWAADLQRSLANERAIRERRAREQADIWVRESCRDRRSAPGVNGGTAMALTLTRGGRDLRRSIGSRRHSTGSDQNWALVRRQDPLGLLQLKADFKWQSWNTLEMVGGLGLIGGLAWLFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3QR37</accession>
    <name>E3QR37_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08469</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697369">
        <property type="protein sequence ID" value="EFQ33325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097345.1">
        <property type="nucleotide sequence ID" value="XM_008099154.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QR37"/>
    <dbReference type="GeneID" id="24413834"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08469"/>
    <dbReference type="eggNOG" id="ENOG502RAIS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1835022_0_0_1"/>
    <dbReference type="OrthoDB" id="4825861at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ33325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="140" mass="16374" checksum="20D3320577D96B20" modified="2011-01-11" version="1">MAIRDHFSRRKSICDPSQSERHRSEPPKSHTLRLAKTFGWRSTKGEKPKKKPKKEKSDPRERPFSETNLRHQEILNGFTMTFGKNHQQMSRDQRSSYISVNVSPGTSRHNSVDVDDSPLRMNPLPCERQFRSVPEEDERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRG1</accession>
    <name>E3QRG1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_08728</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PheA/TfdB FAD monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697370">
        <property type="protein sequence ID" value="EFQ33449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097469.1">
        <property type="nucleotide sequence ID" value="XM_008099278.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRG1"/>
    <dbReference type="STRING" id="645133.E3QRG1"/>
    <dbReference type="GeneID" id="24414093"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08728"/>
    <dbReference type="eggNOG" id="KOG3855">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_9_3_1"/>
    <dbReference type="OrthoDB" id="1716816at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02979">
        <property type="entry name" value="PHOX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012941">
        <property type="entry name" value="Phe_hydrox_C_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038220">
        <property type="entry name" value="PHOX_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF7">
        <property type="entry name" value="P-HYDROXYBENZOATE-M-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07976">
        <property type="entry name" value="Phe_hydrox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="5"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="Phenol hydroxylase-like C-terminal dimerisation" evidence="7">
        <location>
            <begin position="414"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="377"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="377"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ33449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="631" mass="70692" checksum="07A2FFADE741B03E" modified="2011-01-11" version="1">MPMSAVIVGAGPVGLMLSTILARWGYKIKHIDNRAEPTPTGRADGIQPRSLDLLRNMGLKSAIMAHKPARVYEVAFWDPPKSGSGIARTGTWASCPDFIDARYPFTTLLHQGHIERVFISDLSKHGVHIQRPWTITGFTSDEAKNPEYPVEVRLEHVDGTSQETLRAKYLFGGEGARSFIRSQLQIGIKHKDPISHVWGVMDGVVKTDFPDIKMKCTIHSKHGSIMVIPREDNMVRLYIQIASSTEPDFDPRKTATEQEVQESAKRILQPYSIEWERTEWYSVYPIGQGISDRYTLDQRVFLGGDACHTHSPKAGQGMNTAFLDAQNLAWKIHAVESGFARRDILKTYEEERRDVAETLLDFDNKYAKLFSQRPDAASEAQAAATDKSAPEEQSENEFIQTFKEACEFTSGYGVAYKPNALNWSETHSAKSPLIHPEGTKLRTGRLFMNADVTRVVDANVVHLEQEIPLNGSFRIFVFAGKPSTTHNALEDFAKHLDNKRSFFAAYLRDDVKSVSHHEKHNPHSLFFTICTIFAAKRSSIEISRDVPALLARYREHVYADDRWDRRVPNAEAAAHAKLGLDEEKGGVVVVRPDGYVGMVTKLEEGSGTVDALNEYFGAFCTKKLGATLSQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRH4</accession>
    <name>E3QRH4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Pre-mRNA processing factor 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_08741</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697370">
        <property type="protein sequence ID" value="EFQ33462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097482.1">
        <property type="nucleotide sequence ID" value="XM_008099291.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRH4"/>
    <dbReference type="STRING" id="645133.E3QRH4"/>
    <dbReference type="GeneID" id="24414106"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08741"/>
    <dbReference type="eggNOG" id="KOG2769">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015750_2_0_1"/>
    <dbReference type="OrthoDB" id="10264544at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd24162">
        <property type="entry name" value="Prp3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013881">
        <property type="entry name" value="Pre-mRNA_splic_Prp3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027104">
        <property type="entry name" value="Prp3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010541">
        <property type="entry name" value="Prp3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14212">
        <property type="entry name" value="U4/U6-ASSOCIATED RNA SPLICING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14212:SF0">
        <property type="entry name" value="U4_U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08572">
        <property type="entry name" value="PRP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06544">
        <property type="entry name" value="Prp3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pre-mRNA-splicing factor 3" evidence="7">
        <location>
            <begin position="79"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="Small nuclear ribonucleoprotein Prp3 C-terminal" evidence="6">
        <location>
            <begin position="317"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="36"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="49"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ33462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="458" mass="51597" checksum="8127534295325867" modified="2011-01-11" version="1">MAALKARVAAAIGGTKAKGGLNVGLHPVLESLSQAKPLGRTSDVKPSGIRSQFETSSANSSGYRTSDASGRNRNGTQSNPYFNEQLAAQPAGGKQRQARPLHFHPKGKFIQQAAALRRQVALEEMKKRIAAQTRKAGIEDEMNMEKNLVVEAPPDIEWFDEGLVDGTYENIEDESRLKLDKEDTIVTEYIQHPVALEPPQEKNTPAVKPMYLTSKEQKKLRRQRRMAELKEQQAKIRLGLVPAPPPKVKKSNMMRVYADSAVKDPTAVENLVNRQIAERQQNHLQANEERKLTKEEKHDKLAANQEKDAAKGIHVLVFKINSLANGQHRFKIQKNAEQYALTGICVMHPKMNLVVAEGGEHSIRKYKKLMLDRIDWTENTPSREGKTQQQVREWLVAENERGDLKDMSHNECKLVFEGEEKTRAFRKWGNKVCESDAEAKDALARAKMENFWALAKSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRM8</accession>
    <name>E3QRM8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Nuclear membrane fusion protein Kar5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_08795</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for nuclear membrane fusion during karyogamy.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the KAR5 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697371">
        <property type="protein sequence ID" value="EFQ33516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097536.1">
        <property type="nucleotide sequence ID" value="XM_008099345.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRM8"/>
    <dbReference type="GeneID" id="24414160"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08795"/>
    <dbReference type="eggNOG" id="ENOG502QQCT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1266785_0_0_1"/>
    <dbReference type="OrthoDB" id="5311848at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000742">
        <property type="term" value="P:karyogamy involved in conjugation with cellular fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048288">
        <property type="term" value="P:nuclear membrane fusion involved in karyogamy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007292">
        <property type="entry name" value="Nuclear_fusion_Kar5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28012">
        <property type="entry name" value="NUCLEAR FUSION PROTEIN KAR5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28012:SF1">
        <property type="entry name" value="NUCLEAR FUSION PROTEIN KAR5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0415">Karyogamy</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ33516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="218" mass="23584" checksum="CDF064C8114E49B1" modified="2011-01-11" version="1">MTLSCIGNVGAFSWGGNGGRSTLLQASEERIVDPSISIQDKSRLPNVYAVAMQELQELESEPLCHRIAASLLVNNCQLLDGKDDATILTDSGRQVRDFVDSYAASLAICDLERGSFAIPSSCAPFRERSLVNIPDSSIPRLHASPQQIDSCLSGLAKSDSAWNTWVSYRHKALRFCEAARADNEKGTHAPIPDIEIGAHHVLSSPEHSPPPATYRGSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRX8</accession>
    <name>E3QRX8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_08545</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697372">
        <property type="protein sequence ID" value="EFQ33616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097636.1">
        <property type="nucleotide sequence ID" value="XM_008099445.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRX8"/>
    <dbReference type="GeneID" id="24413910"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08545"/>
    <dbReference type="HOGENOM" id="CLU_2757630_0_0_1"/>
    <dbReference type="OrthoDB" id="160645at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ33616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="70" mass="7709" checksum="B898A85E9FCFD228" modified="2011-01-11" version="1">MLLSPETHHTYFVNSGREFAIRVDPSGETMVTFCSSNGNMYPVRTDDADCSKLRATVDDGFVYDGALDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QS04</accession>
    <name>E3QS04_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08571</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697372">
        <property type="protein sequence ID" value="EFQ33642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097662.1">
        <property type="nucleotide sequence ID" value="XM_008099471.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QS04"/>
    <dbReference type="STRING" id="645133.E3QS04"/>
    <dbReference type="GeneID" id="24413936"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08571"/>
    <dbReference type="eggNOG" id="ENOG502S328">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107716_0_1_1"/>
    <dbReference type="OrthoDB" id="8300214at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01443">
        <property type="entry name" value="Cdc25_Acr2p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10828">
        <property type="entry name" value="M-PHASE INDUCER PHOSPHATASE DUAL SPECIFICITY PHOSPHATASE CDC25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10828:SF50">
        <property type="entry name" value="REDUCTASE (ARC2), PUTATIVE (AFU_ORTHOLOGUE AFUA_6G13400)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="46"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ33642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="159" mass="17832" checksum="DB6BEABAB2D961B5" modified="2011-01-11" version="1">MAETAASTETPPWWAAFPAPKAKAPEIEAEEVMRLLEAQDAAGRDAPRHFLLVDVRRDDFEGGTISTSINFPAQSLYQTRPIIHQLCKQAGVKRVIFYCGSSNGRGPRSANWLQDYFDDIGEAAIQAVILKGGIKGWVRKYGSRKMDWYDERSWVDVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSD3</accession>
    <name>E3QSD3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="19">CFEM domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">GLRG_08904</name>
    </gene>
    <organism evidence="20">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
            <topology evidence="2">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697373">
        <property type="protein sequence ID" value="EFQ33760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097780.1">
        <property type="nucleotide sequence ID" value="XM_008099589.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSD3"/>
    <dbReference type="STRING" id="645133.E3QSD3"/>
    <dbReference type="GeneID" id="24414269"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08904"/>
    <dbReference type="eggNOG" id="ENOG502SM6F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_6_2_1"/>
    <dbReference type="OrthoDB" id="2496787at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF160">
        <property type="entry name" value="SAT4 FAMILY MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="14" id="KW-0349">Heme</keyword>
    <keyword evidence="14" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="10 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="8 17" id="KW-0732">Signal</keyword>
    <keyword evidence="7 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180737" evidence="17">
        <location>
            <begin position="20"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="110"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="185"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="222"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="302"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="18">
        <location>
            <begin position="9"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="378"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="397"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="42"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="46"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="56"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="65"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EFQ33760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="461" mass="49906" checksum="8A7580C0DF00D4C6" modified="2011-01-11" version="1">MRFSRYALTAMAVLSGVMSAADQAPAAAQSPAQVAMQMFPKCALFCLAKIIPKSACSQTDVPCLCTNVPLNTQLAGCIMQSCTTYEGLMSKNASMTMCGAPVRNETAKPLLIGVIGGAITFFIFGLRMCAGLPVGGRPWGWDDFTIVIAMALAIPPTVFAVTLSNNGLGKDMWTLPQQQIENVLYYYYLGELFYFAALTATKLSILFFILRVFGMDQKFRPFVYGAMALCLAYGIAFITCTALQCSPISYSWEQIDSKKVGKCNDIHLQGWMSAICNIVIDIIILVLPLKKLAGLQMKLKKKLMIMFMFSLGIFVTIVSVIRLRSLILFANSQNITWDYTEAAWWSTVEIDVGIICACLPSLRSLFIALGVKKLGSTNGNSHGHSSGKRLAGIKPGTNKSGMSSTAEKSAKSAPRQGDERDFIPLVDVDNSKSDFGESLHNVHSTVSASSLTAGAGKNTQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3QT72</accession>
    <name>E3QT72_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitochondrial thiamine pyrophosphate carrier 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">GLRG_09204</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697376">
        <property type="protein sequence ID" value="EFQ34060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098080.1">
        <property type="nucleotide sequence ID" value="XM_008099889.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QT72"/>
    <dbReference type="STRING" id="645133.E3QT72"/>
    <dbReference type="GeneID" id="24414569"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09204"/>
    <dbReference type="eggNOG" id="KOG0752">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_10_9_1"/>
    <dbReference type="OrthoDB" id="270584at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000016">
        <property type="entry name" value="Solute carrier family 25 member 23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24089">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0106">Calcium</keyword>
    <keyword evidence="13 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 14 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5 15" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="34"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="132"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="236"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EFQ34060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="339" mass="36791" checksum="20A81EAD74E5340D" modified="2011-01-11" version="1">MSSSPNNAAGTAAAAPAPPPVPVQFVRLRETVSQPVVAAFCAGGVAGAVSRTVVSPLERLKILFQIQSVGRDAYKLSVGQGLAKMWREEGWRGFMRGNGTNCVRIVPYSAVQFGSYNFYKRSIFESTPNADLSPIARLTCGGMAGITSVFFTYPLDIVRTRLSIQSASFAELGPRSEKLPGMWATMVKMYKTEGGVSALYRGIIPTVAGVAPYVGLNFMVYEWVRKYLTPEGDKNPSAVRKLLAGAISGAVAQTCTYPFDVLRRRFQINTMTGMGYQYKSVTDAVKVIIAQEGLKGMYKGIVPNLLKVAPSMASSWLSFELCRDFLVSLKPEADSETPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTD1</accession>
    <name>E3QTD1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nicotianamine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_09263</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the nicotianamine synthase (NAS)-like family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697376">
        <property type="protein sequence ID" value="EFQ34119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098139.1">
        <property type="nucleotide sequence ID" value="XM_008099948.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTD1"/>
    <dbReference type="STRING" id="645133.E3QTD1"/>
    <dbReference type="GeneID" id="24414628"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09263"/>
    <dbReference type="eggNOG" id="ENOG502QTU6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031919_1_1_1"/>
    <dbReference type="OrthoDB" id="1858069at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030410">
        <property type="term" value="F:nicotianamine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030418">
        <property type="term" value="P:nicotianamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004298">
        <property type="entry name" value="Nicotian_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32266">
        <property type="entry name" value="NICOTIANAMINE SYNTHASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32266:SF12">
        <property type="entry name" value="NICOTIANAMINE SYNTHASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03059">
        <property type="entry name" value="NAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51142">
        <property type="entry name" value="NAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ34119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="324" mass="36333" checksum="91DDB248763DC09E" modified="2011-01-11" version="1">MTTETCGKPSANAGDAVVTIEKPLTGDWSRVQRVSEKLPHNDDPVERIAQGIVELFKRIKGLESLYPNPTNGAILNQLFDLVTTSKTTRAQEEKIMTDARVTAVIPELRQLWGEGEYLLELEFARKVISGKSRAESQVLFESFPYLDQYHQLARMEANTLDTAVGEAQLPRPRKVTFLGSGPTPFTALCMRPRLGRDVEFVNIDRSEEAIQHGSLVARCLGDDMRFVKADVSSIPEDIRDSDVVHFAALIGGDEEQKRDLLISVAKVMKKNALIMFRNTDSLRQCLYPRVDTDDYEVLKYLTPVVTTRYFGKSTSLTSIVFSVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTF8</accession>
    <name>E3QTF8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_09290</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the major facilitator superfamily. DHA1 family. Polyamines/proton antiporter (TC 2.A.1.2.16) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697377">
        <property type="protein sequence ID" value="EFQ34146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098166.1">
        <property type="nucleotide sequence ID" value="XM_008099975.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTF8"/>
    <dbReference type="STRING" id="645133.E3QTF8"/>
    <dbReference type="GeneID" id="24414655"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09290"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_11_6_1"/>
    <dbReference type="OrthoDB" id="446368at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000266">
        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF186">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="167"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="201"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="228"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="307"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="345"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="384"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="411"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="444"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="479"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="76"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="522"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="544"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ34146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="574" mass="62608" checksum="E956B981831611BC" modified="2011-01-11" version="1">MAQANAEKQIEESFEPPVRTRIPYWRQVIDQSGITPEVENHQYAGSGTEADPFLVQWIPHDPRNPMNYSDNTRWFITMMVAFTTLAVSLLSSAYTGGIHDIVREFGISDEVAVLGVSLYVLGFALGPLLWAPLSELYGRQSVFFITYAALAAFGAGCAGAGSARTLIVLRFFAGAFGSSPLSNSGGVIADMFPDEERGLAMTLFSAAPSLGPVFGPIIGGFLGSAAGWRWLMGTLAAISGTFWLLGTALVPETYSPYLLRRRAAELSKRTGKCYVSKMEHHKGKTSLAQSFKTALSRPWKLLFREPIVLLLSLYTAIIYGTLYMLFAAFPIVYQQERGWSQGVGGLPFLGLMVGMIAAVVYSIPENNRYQRVRKRNGGRAPPETRLVSVMVGAIAGPIGLFWFAWTTNPSIHWMASVAAGVPFGFSMILLFMGISNYLIDAYTIFAASVLAANCVIRSLFGAAFPLFTNYMYKNLGTNWASSIPAFLALGCVPFPFLLYKYGAAIRARCKYAAQAEESMAELREELPQSNQDQDDVTAIEGVLSDNTDVPTSSDDSSSVYQKGDQRATSRVSPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTR9</accession>
    <name>E3QTR9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_09375</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697378">
        <property type="protein sequence ID" value="EFQ34231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098251.1">
        <property type="nucleotide sequence ID" value="XM_008100060.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTR9"/>
    <dbReference type="STRING" id="645133.E3QTR9"/>
    <dbReference type="GeneID" id="24414740"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09375"/>
    <dbReference type="eggNOG" id="KOG0156">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_2_1_1"/>
    <dbReference type="OrthoDB" id="1103324at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF6">
        <property type="entry name" value="CYTOCHROME P450 2C30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="462"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ34231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="543" mass="62914" checksum="0421EFCC5843BF15" modified="2011-01-11" version="1">MESFSSLLLYLGVLVVPGLLFSSFRHFSLWTGRRGDDDKARQKRTRFPGPKQYPIVGRVHDLPRFGMWLKLKEWADEFGPIYQTSMLGQKFVIISDEKMAQEVLVKDGNNFAGRPQLRALIDHKLGPTYSALMDRNETWKYQRKWVHAAMAAAHQHQFYGHVDNEVKRWLVTLLLDPEKFHNNTREMTGRIMSRLSWDDSTQGKAYGDSALETLTRMSVSGPIVNTITPIWHLADLVRYNPWRRFEVNRVNNQRAWWLQSFRLAKARFRKGDLPVDTWAYRYFEQLEAGGNKTLEQDGKEEDFAACMLGFQCLVGVVTISGPLQFFLMCMALHPEWLKKCQDEIDMACGDRMPTRDDFAQLPTVRACLKETLRWRSGVPLGVPHQCEKDSEFQGVRIEKGTIVLACEWNINRDPEKYPDYDNYRPDRYLDPSFPTYQEPLTRYPNFREGVGMHTFGWGRRTCLGQTLVDDEMFIAGAGVCWAFDMGLKKCPATGEDVTFDTQATNSNVILEPLPFPMQFRIRSPERAKQVLDEYNKARETLRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUQ3</accession>
    <name>E3QUQ3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SNF2 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09735</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697381">
        <property type="protein sequence ID" value="EFQ34591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098611.1">
        <property type="nucleotide sequence ID" value="XM_008100420.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUQ3"/>
    <dbReference type="GeneID" id="24415100"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09735"/>
    <dbReference type="eggNOG" id="ENOG502T4ZM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_356783_0_0_1"/>
    <dbReference type="OrthoDB" id="10686145at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="786" mass="87868" checksum="3B9AB3987C0E1DCC" modified="2011-01-11" version="1">MGGPKHNSKARSKGTGKDTIPLPDGIVLSGSSIAPASDNEDQQVAFVPGESMEMPTRKKVRKKIKPSTPEFEWYGFPDSDFVASPDWTANKDSAVKGARYNFRHLDITVDKPWIANHRPQWHNDDWAVDHHSSDSTISNVEMRAAMKVRIDAKYPTGGRILFRVSELYYNGWNNNIRNPSTPNLVAILHTLSRDYASTPLLAGILSNDDPDVHEVSNVTMLGESAAGPEANQVHKIGTILLAASHVLKFSPTSPLPDGVNVSADPSAYGHRFQPSTDGKAVAGYTMEDWCRAINIVLIFCYRRTGRTLIASETAPQHKAVTQVIYVPEDDDTGYIGEAEARNSTESMLNRALFKLAPEQNKVRKKLAMLALSQTKIGAVDHVARHEKIISAIQGSTNLTDVIASRCHEQGIHSPVKVDDETMRLLLDVLCDRVEINRHTKSFDAIAPTFSEISPDYNPQHFQDFLEIGCADLHLQVQAARSEPADSQARKEADIAINRAFETWLINSTVSAECPAEDADDLEHISRLQGYTDWRNCAPSSRRPDYKLFPHQVIDSDYMLRLEKTPFKGGIIGHGVGTGKTNIIFNLVAAAADEIDRNIATSSDAPKGPFFPTLVLASTANFSQVWYKSKVFEDKLKFYFYYSSRSVLPKNDGRWNSTWNWDELDRKLHGLDPNDPQTARVVVLSTHSTYFGRTTKYKTIPIRVQPNILPGFLKCASGEDVHPNGRMYALPTHHNKPVVPDNYFQPDCYSVVEDENEAHCFIGLWEITHRLADWKRSWARVIVDEAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUW7</accession>
    <name>E3QUW7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_09799</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697382">
        <property type="protein sequence ID" value="EFQ34655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098675.1">
        <property type="nucleotide sequence ID" value="XM_008100484.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUW7"/>
    <dbReference type="STRING" id="645133.E3QUW7"/>
    <dbReference type="GeneID" id="24415164"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09799"/>
    <dbReference type="eggNOG" id="ENOG502SUMK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_397938_0_0_1"/>
    <dbReference type="OrthoDB" id="39175at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF46">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="2">
        <location>
            <begin position="14"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ34655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="710" mass="78881" checksum="6B32D20C236E0CFE" modified="2011-01-11" version="1">MESQSSRPKKTDIVRKRTGCQNCKSKRKKVINLSPSCDETRPECLACVRRGLQCSGYQRPVTFKDVTSLAAESSKRFEEARWADLRLEDDRRKQRCGRELQETSSTSQDVSLHVTNLPQDPNALTGQELASLPTWNSTNTNIGINGSFILPWALFDTSNAPASDNLFQEASKEISPERNHHPTPSIPSSGLVTVSRGWEVDPPLITDAPSPTLSLTLWDDLINSKDSSSGPTTSTPSPLGSPAADCQLYLPYEEVLVQHFDRNVIPAIPVALAFPSLFSQSSCFRSAVLALAASNLKLTRPLPPDAKSLREICDEESIGVYYDAAVKGLQAHLPYAETHHGEELAGAALLLAYHELEAGTALGIINHATGLDTIAYKLDFAGSPVPGLFKAWRMLRYDLRLMKLPIRRTCNSVDAFDASSLLDSQLAIRDILSRVWGLHARLSMEASFAHDPTVQGASASEKVASWLISVLGRKCDNRNFCLRDFHKDTLTSESILQQCHIFSHRLDNWHKALCDHDLPVVNLGNNSGIINGPTFETFVKYKFADERKTLDYVIYLVCRMGCSYLRSLFDPSATSSSTDALGKVILGIACGMQTHLRQQFTVIRMDMLLAMAACMSEGTNFVTTILDFLIPRIIEHGLTGPDIVAWVWLRSSLELGLRERRKGRIIRMIIDGTDEDSEIWQLVNRHSVAVFGDYNGKGHFRDCYFVEYLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUX3</accession>
    <name>E3QUX3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Amino acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_09805</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697382">
        <property type="protein sequence ID" value="EFQ34661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098681.1">
        <property type="nucleotide sequence ID" value="XM_008100490.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUX3"/>
    <dbReference type="STRING" id="645133.E3QUX3"/>
    <dbReference type="GeneID" id="24415170"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09805"/>
    <dbReference type="eggNOG" id="KOG1286">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007946_12_0_1"/>
    <dbReference type="OrthoDB" id="3900342at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000017">
        <property type="entry name" value="Amino acid permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004840">
        <property type="entry name" value="Amino_acid_permease_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF12">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
        <property type="entry name" value="AMINO_ACID_PERMEASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="114"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="158"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="189"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="225"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="267"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="309"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="364"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="438"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="480"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="518"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="9">
        <location>
            <begin position="80"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="23"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ34661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="585" mass="64253" checksum="36AE69BE5642B220" modified="2011-01-11" version="1">MATEKDIHDGVSTPETTQANTDTRTGAGVGAETATGNASHAVPGRDENFYTRNGLNLESFKRREYGADIVHLDQTMKTRHLHMIAIGGSIGAGFFVGSGSALATGGPGSLLIDFSIIGVMMFNVVYALGELAVMYPVSGGFYVYSTRFIDPSWGFAMGWNYVFQWAIVLPLELTVCGLTINYWEGARGISLAVWITVFWVAIIIINIFGTLGYAEEEFWSSLFKLSAIVIFMIVALILVCGGGPAGGRYDEYWGARYWYDPGAFKNGFKGFCAVFVTAAFSFSGTELVGLAAAEARNPLKSLPGAIKQVFWRITLFYILGLFFVGLLISSNDENILGADNPYADGTSPFVLAAEYAGLYGYNHFMNVIILVSVLSLGVSCVYGGSRTLTGLAQQGYAPRIFTYVDKSGRPLPSVAVHLICGAIAYINLDADGETVFNWLLALSALAALFTWGSICLAHIRFRKAWAYHGHTIDEIPFKAAFGTTGSWIGLILCALVLLATLFVAIAPAGQDELNSAEGFFEAWLTVPIILLFWVIGYFWKGQGWLRTHQMDVDTGRRELDWDEINRYKAEMATWPTWKRMYNRFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVC2</accession>
    <name>E3QVC2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09954</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697384">
        <property type="protein sequence ID" value="EFQ34810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098830.1">
        <property type="nucleotide sequence ID" value="XM_008100639.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVC2"/>
    <dbReference type="GeneID" id="24415319"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09954"/>
    <dbReference type="eggNOG" id="ENOG502R688">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2108848_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="115" mass="12761" checksum="F351F85A5A5B1AD3" modified="2011-01-11" version="1">MVRIPAMRDCVKSKRNGKTWHPEEAGNILVIMGGCSEESVYKGHTGPNPPHKYSSHASEELAKSRSSKYSSELPSDEPSAYRASFNNADIATSEEQGKARVEAEMKRALRQFYGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVV6</accession>
    <name>E3QVV6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_10138</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697386">
        <property type="protein sequence ID" value="EFQ34994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099014.1">
        <property type="nucleotide sequence ID" value="XM_008100823.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVV6"/>
    <dbReference type="GeneID" id="24415503"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10138"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_22_0_1"/>
    <dbReference type="OrthoDB" id="2351791at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1720.10:FF:000018">
        <property type="entry name" value="Putative MFS multidrug transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF94">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="204"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="236"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="307"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="347"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="372"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="397"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="439"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="508"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="45"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ34994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="562" mass="61010" checksum="A33C1C2C5C7ED387" modified="2011-01-11" version="1">MLDPTFESIKSPREYFVPKPDTQAILGEIQETEPEWTPGRAEYAAMATISVISLMVALDATVLVPVLPDLALDLGGSATDAFWAGTSYLLPCAVFQPFIGALSDIFGRKEMLLVSLFFFTLGTLLCAPLARDFTALLAGRSLQGVGGGGIITMGQIIFADIVPLRLRPKYFIFVLGAWAIGSVLGPLLGGLFVEHATWRWCFYINFPFCALGFVMVPLFVRLSTEKSSLGSKLLRVDFLGGFLFIGGMTSFLVGLSWAGIQYEWTSIAVIAPISAGAAAVSFCLLWERYGAAEPFLRRSLFYSWSAVAAYLGAFCQGFLLFCGLYYIPFYFLSVRFVTPTQSGLNLFPVTCLLLPGSIIVSVLTSRLGRFRWAIWSGWAITSTGCGLLVLLDENTTTMMWAICLAVFGIGNGMVLTSVNVGTQAISRVEDCGRAACMYAFMRTLGMSVGVAVGGTTFQNVMTNRLQELGMSEAIAKNAEIYATHLAAMDSADPERIGALSAYVTGFRGVFWVMTATAAFGFLSSLIIRKHTMDRTHESKFTLQGAKNRKSEVPSVVSNVIKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QW66</accession>
    <name>E3QW66_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TBC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_10244</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697388">
        <property type="protein sequence ID" value="EFQ35100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099120.1">
        <property type="nucleotide sequence ID" value="XM_008100929.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QW66"/>
    <dbReference type="STRING" id="645133.E3QW66"/>
    <dbReference type="GeneID" id="24415609"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10244"/>
    <dbReference type="eggNOG" id="KOG2058">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005609_0_0_1"/>
    <dbReference type="OrthoDB" id="294251at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.270:FF:000026">
        <property type="entry name" value="TBC (Tre-2/Bub2/Cdc16) domain family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.80:FF:000046">
        <property type="entry name" value="TBC domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF20">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="3">
        <location>
            <begin position="752"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="302"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="368"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="508"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1000"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="165"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="18"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="336"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="373"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="389"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="559"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1000"/>
            <end position="1028"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ35100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1072" mass="116421" checksum="E1664EFD008C37D2" modified="2011-01-11" version="1">MDSEPPSLPLERSVSQHSAASIRSTRSSALRVKRSKLTSQPSSSASSIAASEDKSLTSFPSIPPDSPTPEHAFPPVSPTTSLPEPEPPATVRKISDTRHSPISLLGGLAGGPSAEHTARDALFEDSPISTHKIPGALHHADDEHIGRLIARHGAVALVRQVATDLAQRDAQIAQLRRKADERERALRKIILECGLSNLELETRLRAVESEVKTTRPGNRRNESGLSDLMSDAMQDTVIYNVFGQTEVSDATIRASNLATSSNPDGRGTARGWKDYLWGGSSRKGSVPSSVNGDDLRPATFLRTQSSADKRPGLQDDLFSPPGEGLFPDSVPPRTPSRASSIQSGPPGSRKPSTSVAASLMRLVAGGAINTRESGSNRGRSNSATHPQPTARASSTSSAKTTQSSRAVSTQGGPKALMAMRRTGTNLNSLQPATATRTQPQERWDAMLSPTATTANRQESYGPVEMDAILPPETQPPTLTHIYNNYIGSEYLTDRFGFIYDQRRKKRQREAAQMAHHLKQGSRAEMLSNGRSDLSSPMIEEEEVSSPLSGEDGPDSPSSAEERAGEGGRSKKWQDYLKLATFPTELLSHTPALSAPSLEVLEGGELGTKSPGLITADERGFVPIASTTTSVIDSDATPPVETDAAGGTVVRDDTEPVKLLLQHMGDLHDSLQRVKAARWNEFLRKVRAERKRDGEAAAAAAAALAEARYERPTVNLPEAAFADGELIGITGLGIKGKVGRAKRTELRNLVLGGIPVNLRAKVWSECSGANTLRVPGYYQDIIARSDKDDDPTAVSQIEMDINRTLTDNIFFRKGPGVSKLKEVLRAYARRNPEVGYCQGMNLIAANLLLIMPSAEDAFWILTSIVENILPSGYYDHSLLASRADQQVLRRYVADVLPKLSQHLDDLSIELEALTFQWFLSVFTDCLCAEALFRVWDVVLCMNDGSTFLFQVALALLKLNEPQLLQCDTPASVYTYINRQMTNHAISIDNMIKASDGLRKEVKREDVEARRDKAIQTEKDAARRREEMNAAKKTGKVNGNGNGNGHDSGHEESEAATPGLDLRDPMPMEQEEQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWB7</accession>
    <name>E3QWB7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cyclopentanone 1,2-monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_10295</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697388">
        <property type="protein sequence ID" value="EFQ35151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099171.1">
        <property type="nucleotide sequence ID" value="XM_008100980.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWB7"/>
    <dbReference type="STRING" id="645133.E3QWB7"/>
    <dbReference type="GeneID" id="24415660"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10295"/>
    <dbReference type="eggNOG" id="KOG1399">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006937_8_0_1"/>
    <dbReference type="OrthoDB" id="66881at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050775">
        <property type="entry name" value="FAD-binding_Monooxygenases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43098">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43098:SF3">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="8">
        <location>
            <begin position="31"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ35151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="562" mass="63508" checksum="77678F25D29D59F6" modified="2011-01-11" version="1">MGSIDYTDYFDNGRLNGKGFCSDAQSKNMDYDVTIIGGGFGGCYALHLLRKQGFSAHIVEAGSSLGGVWHWNSYPGARVDSEAPYYQLTVREVWKDWTWTERFPGHEELKGYFRHIDKVLDISKDVSYNTTVVGADFDTDTARWIVKTNTSRSITSRFLVSATGSSYKRYEPSFAGKESFRGTVVHSAAWPESGVDFRNKRVAILGAGATGVQCVQEIAKQPGMELTVYRTSKSFYEILFKAARESNYGIPSESNPKSTSETTAEERDALWEELWQRGGFSFQAGQYTDFLIDAESNRLAYEFWAKKTRGRIRNPQKGAMLVPDEPPYPFATKRSSLEQDYYKCLDQDKVEVVDVKSSGIREWTPRGIMTEDGREREHDIILLATGYDSMTGALTNMGLRGKDGVDLKERWKDGVWTYLGFMARGCPNLFFVYGPQAPMAFTNGPPFIEKQVEVIVDFLTKLRKERVRSVEPHPSAVEQWKKIILANHEPTLFSKCESSWYVGANIPGKKREQLNYLGGIPLYLQACRDGTSNWDNFDVVREEEGRKVVDAVSVRPMEGITT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QX43</accession>
    <name>E3QX43_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10575</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697393">
        <property type="protein sequence ID" value="EFQ35431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099451.1">
        <property type="nucleotide sequence ID" value="XM_008101260.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QX43"/>
    <dbReference type="GeneID" id="24415940"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10575"/>
    <dbReference type="eggNOG" id="ENOG502TH65">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_121516_1_0_1"/>
    <dbReference type="OrthoDB" id="2590756at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="138" mass="14871" checksum="7195845E6901FEE7" modified="2011-01-11" version="1">MPLFQASKLPFFLHIAIETASACSFIFNPASQLPDPSPATRLVLQSFGGLLLSTNLVCLAFVARPFDETTRRVAAALAFWHAWPCWRAYVRLARPVVDGTGKDKHKGELVKKTLGGPGVHLAVHVGMFVLFAGAALVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXF6</accession>
    <name>E3QXF6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fatty acid desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_10688</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697395">
        <property type="protein sequence ID" value="EFQ35544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099564.1">
        <property type="nucleotide sequence ID" value="XM_008101373.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXF6"/>
    <dbReference type="STRING" id="645133.E3QXF6"/>
    <dbReference type="GeneID" id="24416053"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10688"/>
    <dbReference type="eggNOG" id="ENOG502QQNB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033094_0_0_1"/>
    <dbReference type="OrthoDB" id="1461976at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03507">
        <property type="entry name" value="Delta12-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32100">
        <property type="entry name" value="OMEGA-6 FATTY ACID DESATURASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="303"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="331"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid desaturase" evidence="3">
        <location>
            <begin position="140"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ35544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="481" mass="53174" checksum="D0F974E4957F78A8" modified="2011-01-11" version="1">MASTTSMPAAQNPVLRRTVTSTTAETDASMPSTAVASPMDSPRPSASSTSLSSMASEGAAPKTANYGKLYDTYGNEFTPPDFTIKDIYNAIPKHCFERSALRGFGYIARDILCLATTFAIWYNFVTPEYVPSKAVRAGLWGLYTVLQGLFGTGLWVIAHECGHQAFSPSKTLNHAVGWVLHSSLLVPYFSWQISHSKHHKATGHMERDMVFVPRTREQQATRAGRLAHEVGELAEETPIFTLLMLIAQQLVGWPNYLMTNVTGHNFHERQREGRGKGKHNGLGGGVNHFDPSSPLFEAKDAKLIILSDIGIGITATVLVLLGNKFGWSNLLVWYFIPYLWVNHWLVAITFLQHTDPTLPHYTADQWNFVRGAAATIDREMGFIGRHLLHGIVETHVLHHYISTIPFYNADEASEAIKPVMGKHYRADVQDGPVGFIKALYKSARMCQWVEPSVGAQGEGKGVLFFRNHNGLGTPPIKGEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXI5</accession>
    <name>E3QXI5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cell wall protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_10717</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697396">
        <property type="protein sequence ID" value="EFQ35573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099593.1">
        <property type="nucleotide sequence ID" value="XM_008101402.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXI5"/>
    <dbReference type="STRING" id="645133.E3QXI5"/>
    <dbReference type="GeneID" id="24416082"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10717"/>
    <dbReference type="eggNOG" id="ENOG502R99E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090704_0_0_1"/>
    <dbReference type="OrthoDB" id="2422134at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021054">
        <property type="entry name" value="Cell_wall_mannoprotein_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38123">
        <property type="entry name" value="CELL WALL SERINE-THREONINE-RICH GALACTOMANNOPROTEIN MP1 (AFU_ORTHOLOGUE AFUA_4G03240)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38123:SF6">
        <property type="entry name" value="CELL WALL SERINE-THREONINE-RICH GALACTOMANNOPROTEIN MP1 (AFU_ORTHOLOGUE AFUA_4G03240)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12296">
        <property type="entry name" value="HsbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180006" description="Cell wall protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ35573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="268" mass="28176" checksum="0C3EBE20D9FCF89B" modified="2011-01-11" version="1">MHSQYVVLALLSRAALLTAAPFKSTTAFEKRDNLATIETALSPVFGALSAVDLAVVSLDGTTISAQNLYVASQRVETTVKEATIIVRATGDLTVSKSLKLRKSTDTLAAQTKTTLDDLVSRKAVLDTLGFGGTVLLSLQQQEAATMSLSQALAQKVPMIGQPQAASDVSNMEAMFNKAIAAFSVVEVPVVVPVTPVTPVPVPVTPVVPVTPVVPVTPVVPVTPVPAPVIIAPKKAKSEKDEMNEMNETDETNEADEMDDIDALAEDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYV7</accession>
    <name>E3QYV7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">26S proteasome regulatory subunit 6A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_11189</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697407">
        <property type="protein sequence ID" value="EFQ36045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100065.1">
        <property type="nucleotide sequence ID" value="XM_008101874.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYV7"/>
    <dbReference type="STRING" id="645133.E3QYV7"/>
    <dbReference type="GeneID" id="24416554"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11189"/>
    <dbReference type="eggNOG" id="KOG0652">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000688_2_4_1"/>
    <dbReference type="OrthoDB" id="9443236at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045899">
        <property type="term" value="P:positive regulation of RNA polymerase II transcription preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070682">
        <property type="term" value="P:proteasome regulatory particle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000009">
        <property type="entry name" value="26S protease regulatory subunit 6A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000076">
        <property type="entry name" value="26S protease regulatory subunit 6A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000037">
        <property type="entry name" value="26S protease regulatory subunit 6A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032501">
        <property type="entry name" value="Prot_ATP_ID_OB_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16450">
        <property type="entry name" value="Prot_ATP_ID_OB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7 14" id="KW-0647">Proteasome</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="13">
        <location>
            <begin position="240"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="10"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00069320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ36045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="460" mass="51154" checksum="5600DC0BF2ABF6AB" modified="2011-01-11" version="1">MSTLEELDDLDRHDKNDKRDDGDKDKDNKKSAAEGDADMKDAEEEEDILDEEILNLSTQDIQTRKRLLENDSRIMRSELQRLTHEKATMGEKIKENLDKIANNRQLPYLVGNVVELLDLDPTAESSEEGANIDLDATRVGKSAVIKTSTRQTIFLPLIGLVDPTTLKPGDLIGVNKDSYLILDTLPAEYDSRVKAMEVDEKPTEKYTDVGGLDKQIEELVEAIVWPMKEAERFKKIGIKAPKGALMYGPPGTGKTLLARACAAQTDATFLKLAGPQLVQMFIGDGAKLVRDCFALAKEKAPAIIFIDELDAVGTKRFDSEKSGDREVQRTMLELLNQLDGFASDDRIKVLAATNRVDVLDPALLRSGRLDRKIEFPLPNEEARAQILKIHSRKMKVDTAVNWGELARSTDEFGGAMLKAVCVEAGMIALRMGKNKISHEHYVDAIAEVQAKKKDTVNFYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZ71</accession>
    <name>E3QZ71_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polysaccharide deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11303</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697411">
        <property type="protein sequence ID" value="EFQ36159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100179.1">
        <property type="nucleotide sequence ID" value="XM_008101988.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZ71"/>
    <dbReference type="GeneID" id="24416668"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11303"/>
    <dbReference type="eggNOG" id="ENOG502QU9T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029940_1_0_1"/>
    <dbReference type="OrthoDB" id="3162524at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10938">
        <property type="entry name" value="CE4_HpPgdA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037950">
        <property type="entry name" value="PgdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47561">
        <property type="entry name" value="POLYSACCHARIDE DEACETYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G05030)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47561:SF1">
        <property type="entry name" value="POLYSACCHARIDE DEACETYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G05030)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="1">
        <location>
            <begin position="29"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="317" mass="36683" checksum="D5201B19B2000043" modified="2011-01-11" version="1">MGKKKALVCYGVDIDAVAGWLGSYGGEDSTSDISRGLWAGTIGTRRLLKLFEKYNIKASWFIPGHTLETFPEECAMVRDAGHEIGLHGYSHENPVDMTLEQQRDVLDKTWKMLTEFCGKPPKGSVAPWWETSEEGTELLLSYGIEYDHSMSHHDCQAYWLRTGDTWAKIDYTQKAEAWMKPLVKGKETGLVEIPGSWYIDDLPPMMFMKNSANSHGWVNPRDVEDIWRDHFDYFYREYDEFIFPMTIHPDVSGRPHVLLMHERVIEHINKHEGVEWVTMGEMSDYFKSKNSVPEGGLMPARQEEVMKKYEEWKKTQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZ87</accession>
    <name>E3QZ87_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">VHS domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_11316</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Component of the ESCRT-0 complex composed of HSE1 and VPS27.</text>
    </comment>
    <dbReference type="EMBL" id="GG697413">
        <property type="protein sequence ID" value="EFQ36175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100195.1">
        <property type="nucleotide sequence ID" value="XM_008102004.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZ87"/>
    <dbReference type="STRING" id="645133.E3QZ87"/>
    <dbReference type="GeneID" id="24416680"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11316"/>
    <dbReference type="eggNOG" id="KOG1087">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036827_0_0_1"/>
    <dbReference type="OrthoDB" id="10068368at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051666">
        <property type="term" value="P:actin cortical patch localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14232">
        <property type="entry name" value="GAT_LSB5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16980">
        <property type="entry name" value="VHS_Lsb5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004152">
        <property type="entry name" value="GAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044103">
        <property type="entry name" value="GAT_LSB5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038425">
        <property type="entry name" value="GAT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045007">
        <property type="entry name" value="LSB5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002014">
        <property type="entry name" value="VHS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47789">
        <property type="entry name" value="LAS SEVENTEEN-BINDING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47789:SF1">
        <property type="entry name" value="LAS SEVENTEEN-BINDING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00790">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00288">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89009">
        <property type="entry name" value="GAT-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50909">
        <property type="entry name" value="GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50179">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="VHS" evidence="5">
        <location>
            <begin position="41"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="GAT" evidence="6">
        <location>
            <begin position="267"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="165"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="378"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="171"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="220"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="248"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="403"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="442"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="452"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ36175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="470" mass="52049" checksum="C3297919363CB597" modified="2011-01-11" version="1">MARASNRHGQTNPPSTVLTERALIRPQKKPYSAVTVSIETLTSETYDEDDLSGIPDLVEVIKLQASGPAEAARAIRKKLKYGNVHRQLRALTILDGLIQNAGPRFQRAFADETLLERLRVCGTSDLSDPDVKKKCTELFRSWSQYKSTPGLERIARLHQELPKRKVAVTQERSKAVRETENPFGEEEEDKPPSPPLAPARAGESSRPQRTPYLPYGGGESAASAASRAGGHSKSSSHSGGSFFGSSKDKKKKDKEKKGKRKPFNLELEKDAMKSTIAESSIATTNLTNHLQSINRERERISENPQAVQQFENCKQLRRKILRYIHHIESEEWLGSLLRANDELVTALMTFEQLDRSIDADSDSDDELAEQAHIYRMVSEKAKQSMSPPPPDVSGLSIGQTPSSRPPPPPRPVPMSKPSPSVPAPAPAKPPRPPVQRAQSDSEGGEEDDDDPFADRNALETPATERPEPRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZX4</accession>
    <name>E3QZX4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nuclear pore protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11540</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697423">
        <property type="protein sequence ID" value="EFQ36412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100432.1">
        <property type="nucleotide sequence ID" value="XM_008102241.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZX4"/>
    <dbReference type="STRING" id="645133.E3QZX4"/>
    <dbReference type="GeneID" id="24416904"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11540"/>
    <dbReference type="eggNOG" id="ENOG502RS6N">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042420_3_1_1"/>
    <dbReference type="OrthoDB" id="5275938at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="354" mass="38791" checksum="103DB1F7BADEB5D0" modified="2011-01-11" version="1">MNYADGVDSTSEEVQVDPDGDLVLRAGQQTGLPERSFRVCANALRRSSQVWKKMLFGPFKESKPAFGTWLVHLPDDDPDALEIVLNIIHANFPLVPATPGLAELYEIFQMANKYDMVPALKPWANAWLDVAESCAAVTDGESMAALTYVAWELGQVELHRKMMKELLLYSSIDGDGRMVTADGVVLDDSDPIGPPGLLGFLRKQHQEIFNTLPSQLNDVIAKLTTGPGCCVDKKASSDERADCNDIILGSLVRGMAKTRGSISLTMPVSEGESVAKFAGTIRTIAEGISSHEQHGRKCNPAPRIIAALNKFTRGRVVKLTKMSVEKMEVRREELGLDKPRSQKPSEWSLSLLIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0V1</accession>
    <name>E3R0V1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_11885</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697498">
        <property type="protein sequence ID" value="EFQ36739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100759.1">
        <property type="nucleotide sequence ID" value="XM_008102568.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0V1"/>
    <dbReference type="STRING" id="645133.E3R0V1"/>
    <dbReference type="GeneID" id="24417248"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11885"/>
    <dbReference type="HOGENOM" id="CLU_002341_4_2_1"/>
    <dbReference type="OrthoDB" id="4851075at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF5">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ36739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="413" mass="47263" checksum="D81CDEE56781AEDF" modified="2011-01-11" version="1">MAELAAIGLVSNLLQFTELGVKLFIHAREAYRTGTIVQDEALRSEVHKGEKIYKRIWASLEQALKTLSNQKTTAAFEQRLVKLKYDLQFYLVGASVQAQKETKVMIERLKDQNDRQGTSTTERLDRILIRIETLACSLKDHDNEEFRAHIEKFKSVLEEFHQAKAVLERQHDILKSLRHFLDPREGWKREINIDEIPRFSGRAEKFDVETASLGWEVQSRGKQPLLLACRQQHAEVPTRSSPDPAVRYIEGTPGSHRNGLQITLGKSIHMLGDSWGLLELMAAFDVLASNHNKDLPVKFCFFIDGLDEYTGGAEKYHGQFEDLLATLYKLASLPSVKLCVSSRPWPAFNESLGLKVGEWHLQVEDLTRDDIKRVVMERLSATHDYKRLSNQDPRCSEIPAEIVQRAQGVWYLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q285</accession>
    <name>E3Q285_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00330</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089206.1">
        <property type="nucleotide sequence ID" value="XM_008091015.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q285"/>
    <dbReference type="GeneID" id="24405695"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00330"/>
    <dbReference type="eggNOG" id="ENOG502QYHE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1686432_0_0_1"/>
    <dbReference type="OrthoDB" id="4847810at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="156" mass="17006" checksum="FAB82A069B1F9DB0" modified="2011-01-11" version="1">MASKGAKKGIDAKAKPISNASQKPNSWHTDPYPCTAPRCIEVVKLVGQFMDLSMDYKVPDETTYGFYAAVIEELKAQYAAMAADSGDLKQKLSGLFREWQDQGETPMDAEVVGAVARMKIFMAAWTRTVDEIETLKSVDGSLAKPSKARKPAKGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2F6</accession>
    <name>E3Q2F6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tyrosine specific protein phosphatases domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00401</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089277.1">
        <property type="nucleotide sequence ID" value="XM_008091086.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2F6"/>
    <dbReference type="STRING" id="645133.E3Q2F6"/>
    <dbReference type="GeneID" id="24405766"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00401"/>
    <dbReference type="eggNOG" id="KOG2386">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013931_1_0_1"/>
    <dbReference type="OrthoDB" id="428974at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140096">
        <property type="term" value="F:catalytic activity, acting on a protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004484">
        <property type="term" value="F:mRNA guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006370">
        <property type="term" value="P:7-methylguanosine mRNA capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14502">
        <property type="entry name" value="RNA_5'-triphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000273">
        <property type="entry name" value="Dual specificity phosphatase catalytic domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000090">
        <property type="entry name" value="Dual specificity phosphatase catalytic domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051029">
        <property type="entry name" value="mRNA_Capping_Enz/RNA_Phosphat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003595">
        <property type="entry name" value="Tyr_Pase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10367:SF25">
        <property type="entry name" value="DUAL SPECIFICITY PHOSPHATASE CATALYTIC DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G03540)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10367">
        <property type="entry name" value="MRNA-CAPPING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00404">
        <property type="entry name" value="PTPc_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="2">
        <location>
            <begin position="537"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="326"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ25257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="638" mass="71294" checksum="41B7ED331D792B14" modified="2011-01-11" version="1">MADQQQAAAQPTSANPHDPDATDPPLLRDNSEFREYSTDRYTYSGIRTFYKRHLQADQLPKPPLPLLVFVHGLGGSVAQFHPLLMSLVHISSCLAIDLPGCGRSEFSEQAWDAYTPEALGELLEVIIDDYRQKEPDRNVILIGHSMGTALCARLASRNVAHKTKLRKHVVGLVAICPVAGPPGEQKTKIFRTLLWIPGWLFDLWRAYDRWGGPQSTSVSRFVGPEADFELRTLQDRFNNQSRTPIWRRMAWGSLPTFETGVAKGGVPGKDVWAGLDVPVFLVGGAEDKLTPPSEVEKIKEYLSGKAPSSPETGSDDGHETIVDAAATANLSKDPKDHGPESIDDIRDEDFHRDRRPSDEADSTFEDPSTPQESPANVPPQPRHPTKVVKSIIMPAPANHALLFNPATVRVLAGLVSDFLTNHVTGRFSLGWQLQYLSREGKWDVKNLAKWKGVVPVSQPIGPKGKPAVFRAMKTLREADDTHSPAEFVKNWGGIIKDVIDISHDKPVYDPRTMEKGGVRYHKYATVSKIPPKDDEVVHFVSLVDKLREQQKTRAEEEKWTEVDGQTQVIGVHCHYGFNRTGYFIVCYLVERCGMDVGEAIDTFKAARPNGIRHHHFRDRLHMRYSGLKLEEDQQGVSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2I5</accession>
    <name>E3Q2I5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily transporter protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_00430</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089306.1">
        <property type="nucleotide sequence ID" value="XM_008091115.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2I5"/>
    <dbReference type="GeneID" id="24405795"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00430"/>
    <dbReference type="eggNOG" id="ENOG502QQA7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_912173_0_0_1"/>
    <dbReference type="OrthoDB" id="413079at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000308">
        <property type="entry name" value="MFS efflux transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051788">
        <property type="entry name" value="MFS_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514:SF3">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="104"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="222"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ25286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="305" mass="32484" checksum="C0A251880F08C068" modified="2011-01-11" version="1">MHASRGCGGGGGPEFTFHKLWAALSLVLPCHPRNISRRLGSLEKYYNLTYVVISLIFLSPFLGYVPLALLNTHVHLRWGQRGIAILASTCHVVAYVIIAQHPPYPALVVVFILAGLGNGLSDAGWNAYIGNMERADEVLGFLHACYGVGGVVSPLIATTMTTKENLGWWMFYYVMIALAVIEIVWCTAAFWTQTGAVYRETISHSGNDGSAGLPTALFKRPYISAVAVALQGFFLGPLFPAVVVATTRLLPRHLHVSTIGFAAAFGGGDPALRRGRPGAGQGRAGLAALHPCVLGGYDGVVALLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2Y4</accession>
    <name>E3Q2Y4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">G10 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_00107</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the BUD31 (G10) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ24963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008088983.1">
        <property type="nucleotide sequence ID" value="XM_008090792.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2Y4"/>
    <dbReference type="STRING" id="645133.E3Q2Y4"/>
    <dbReference type="GeneID" id="24405472"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00107"/>
    <dbReference type="eggNOG" id="KOG3404">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087132_1_1_1"/>
    <dbReference type="OrthoDB" id="277109at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001748">
        <property type="entry name" value="BUD31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018230">
        <property type="entry name" value="BUD31/G10-rel_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19411:SF0">
        <property type="entry name" value="PROTEIN BUD31 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19411">
        <property type="entry name" value="PROTEIN BUD31-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01125">
        <property type="entry name" value="BUD31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00322">
        <property type="entry name" value="G10"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00997">
        <property type="entry name" value="G10_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ24963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="147" mass="17068" checksum="F95133C1EBA06FFB" modified="2011-01-11" version="1">MPPMRSSKRKPPPEGFSDIEDQLLIFQNKMKDAQNKPPPTGPKHQAQWEIFQIAHTRSRYIYDLYYEKEAISKQLYEWLLKNGYADAMLIAKWKKQGYEKLCCLRCVQTKETNFNSTCICRVPKAQLKEDQEVQCVNCGCHGCASSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q432</accession>
    <name>E3Q432_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00488</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089364.1">
        <property type="nucleotide sequence ID" value="XM_008091173.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q432"/>
    <dbReference type="GeneID" id="24405853"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00488"/>
    <dbReference type="eggNOG" id="ENOG502T4MK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_341312_0_0_1"/>
    <dbReference type="OrthoDB" id="4851153at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="528"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="611"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="650"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="723"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="389"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="450"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="665"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="723"/>
            <end position="735"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ25344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="861" mass="96301" checksum="DEB5006BFDC42D0D" modified="2011-01-11" version="1">MDGFLDWVCPQAEKMLDFLIDMFGIIFGPIMYGLLWMTSFSSIGFAIWIIVGSLILGARKLFQDATRSLKDQWRALSDNDPNKPRIPVWYRRPSYAVCDPITDSSNPSKDGKKKKSDKKKLSLRISQTKAKKIATRLRRKTSRLEYRHRQEHKTNPWPTRKHQKTVELNSKIEKLKSCNLELSAYLRTVEASRAELLQRQTTWIYPYDKDLEIPGRIPTICARLPVPEFRISDVVGRRKAKPAAPFNITFYSMPETIVRSKASAPAARSLSRVNNKTIEQTANQPVTTPAVIPSPPITIPTVNTLGQIPKHTESPVTRVLGLPQPLANSVPLPKSPPQPLAQSPSTPPSLIHPSSQIVTPAFPAVSKNNNGEVSQEDRPAKESKKEASDYNTSSKSNNDENNNTALPSISEPDEDAGKSKDENLTLLPDSDENDVEGRDDNFPPLPDSDTGSDGEDDDEDRNDRPDNAGSVIPSVIQQLVETFSDPAPAQESPFTSSSAPAIIKPNVQEPSITPLGTQMEVDIHNENVTEEEHTKLDAMDVDVQDEKSGKECGAAKDEMEVDIEHEKTKDDTGKDKMEVDIENETGATTDEMQLDDMDLIRGLKDVDMVNASQKIQKPTGDIEMRDGPTTPSIAPNPNVFAEQNARHTIAEQPSTPLPNKHCSHQGMQRPQVSNVRGETMSDKAPPPAPESKNQRPVIVIRHNESRRQRALEAKRRWLLAQEQEAADAPEPAMEQFRNRPPPMVSSQGVSARDNRLLLSGTPELRRELLHRLQALWPLLPKAEVDRSLAEWRKLLNPAGKHALPDNTYIPRDAFEREAAEWMKKVLELMTKLKVVPEVGSLLETWRECMARQEPLPEPEDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4M2</accession>
    <name>E3Q4M2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CENP-V/GFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_01181</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ26037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090057.1">
        <property type="nucleotide sequence ID" value="XM_008091866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4M2"/>
    <dbReference type="STRING" id="645133.E3Q4M2"/>
    <dbReference type="GeneID" id="24406546"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01181"/>
    <dbReference type="eggNOG" id="ENOG502RZKF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055491_3_6_1"/>
    <dbReference type="OrthoDB" id="428768at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1590.10">
        <property type="entry name" value="glutathione-dependent formaldehyde- activating enzyme (gfa)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337:SF8">
        <property type="entry name" value="CENP-V_GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337">
        <property type="entry name" value="GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="5">
        <location>
            <begin position="2"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ26037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="109" mass="12266" checksum="E5DC0F0D45945214" modified="2011-01-11" version="1" fragment="single">LVVADSHLRHVRGKENLKSFTQSKTIASGNDMTNYFCKTCGTLLYRVSSGFPNMSVLRIGTVDGFRLAETKLKPQLEQFVGTRVGWLAPVEDILQIERNLTLEDIRNIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5B4</accession>
    <name>E3Q5B4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CAIB/BAIF family enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_01025</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089901.1">
        <property type="nucleotide sequence ID" value="XM_008091710.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5B4"/>
    <dbReference type="STRING" id="645133.E3Q5B4"/>
    <dbReference type="GeneID" id="24406390"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01025"/>
    <dbReference type="eggNOG" id="ENOG502QUIE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_153284_0_0_1"/>
    <dbReference type="OrthoDB" id="5863171at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025496">
        <property type="entry name" value="DUF4387"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14330">
        <property type="entry name" value="DUF4387"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4387" evidence="1">
        <location>
            <begin position="4"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="113" mass="12161" checksum="88BEF70D41DF4845" modified="2011-01-11" version="1" fragment="single">PETLSDISRVLRSKNAGPYEITMDVMFESKSVFDAVKVSSLLSAEHVADALGIGLEDIIWPGFFAPALAFKVTIPRFRGGKKTSAGSFMKSDIHGSQQHLGLSIMKLPPGLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5Y2</accession>
    <name>E3Q5Y2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">T-complex protein 1 subunit delta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_01374</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090250.1">
        <property type="nucleotide sequence ID" value="XM_008092059.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5Y2"/>
    <dbReference type="STRING" id="645133.E3Q5Y2"/>
    <dbReference type="GeneID" id="24406739"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01374"/>
    <dbReference type="eggNOG" id="KOG0358">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008891_9_1_1"/>
    <dbReference type="OrthoDB" id="10248520at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd03338">
        <property type="entry name" value="TCP1_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000010">
        <property type="entry name" value="T-complex protein 1 subunit delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012717">
        <property type="entry name" value="Chap_CCT_delta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053374">
        <property type="entry name" value="TCP-1_chaperonin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054827">
        <property type="entry name" value="thermosome_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02342">
        <property type="entry name" value="chap_CCT_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041082">
        <property type="entry name" value="thermosome_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041083">
        <property type="entry name" value="thermosome_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ26230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="535" mass="56824" checksum="43D3743B6D3E072E" modified="2011-01-11" version="1">MATAAPPPASGGSGNATFKDKEKPVAVRSSNIVAARAVADAIRTSLGPRGMDKMIRSGKGETIITNDGNTMLKSMSVMHPTAKMLVNLSAAQDVEAGDGTTSVVVICGSLLGAADRLLSKGIHPSVISESFQRAAAAAVEVLHGMSQPISLTDTASLLQAANTSLSSKIVSQYSNILGPMAVNSVVKTIDLKTADNVDLKNIRIVKKVGGTIEDSELSDGLILTQPVLKGAGGPARIEKARIGLIQFQLSPPKPDMENTIQVNDYRQMDKIVKEERLYLLNMVKKIKKAKCNVLFIQKSILRDAVNDLSLHFLAKLGILAVKDIERDEIEFICKSTGCKPIADIDSFTEDKLGSADLVEEVQSNGARMVKVTGAKATGKTVSVVVRGANSLILDEAERSLHDAHCVVRCLVKKKALIAGGGAAEIEIASQLSKQARELTGTEAICWKAFADAMEVIPTTLAENAGLNSIKVVTELRHRHELGEKNAGVSIKSGGVNTNISKENVLQPLLVSTSAIELAAETVKMILRIDDIALTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q651</accession>
    <name>E3Q651_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Calcineurin-like phosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_01443</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090319.1">
        <property type="nucleotide sequence ID" value="XM_008092128.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q651"/>
    <dbReference type="GeneID" id="24406808"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01443"/>
    <dbReference type="eggNOG" id="KOG3947">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041441_2_0_1"/>
    <dbReference type="OrthoDB" id="630188at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07379">
        <property type="entry name" value="MPP_239FB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051693">
        <property type="entry name" value="UPF0046_metallophosphoest"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12905:SF0">
        <property type="entry name" value="CALCINEURIN-LIKE PHOSPHOESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12905">
        <property type="entry name" value="METALLOPHOSPHOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="327" mass="36282" checksum="66651166F469355B" modified="2011-01-11" version="1">MTIREGFVETRIFVISDTHGLRLPYIPHADVVIHCGDLTNESELQEYRNLIQDLSSVEAPLKLVVPGNHDFTLDIPTFKRRIVEVQQGNPEVNEKYTEKYGNPGDARSLFEAARNAGIVLLEEGTHIFKLANGARLKVYTSPYTPAAGGFPGFQYQPEDSHDFAIEKGTDIAITHGPALGMLDHTEANPKAGCPDLLDAIARARPQLHCCGHIHESAGARMVTWSEHPAEESTRTGEDGFKDSSVIVTLRDIKSLPTNSIKETVRKRHLVKQSSFNMCFEISLCQGDWRPLDFKSQTLFVNAAIQGAPGEAELYCPWMIDIELPKAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q675</accession>
    <name>E3Q675_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">V-type c subunit family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_01467</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090343.1">
        <property type="nucleotide sequence ID" value="XM_008092152.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q675"/>
    <dbReference type="STRING" id="645133.E3Q675"/>
    <dbReference type="GeneID" id="24406832"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01467"/>
    <dbReference type="eggNOG" id="ENOG502SB4N">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014048_1_0_1"/>
    <dbReference type="OrthoDB" id="9988102at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ26323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="494" mass="54919" checksum="9E57EDC9A0E5AF74" modified="2011-01-11" version="1">MVRVPGYAKLIAPKSHRGHAIFSVHGNERSHKYGLVDVVHKTFHGLRRGPLELQDALVVLASRQYASWLQDNEFMATLVNLFHGRPSNKKKDSHHPEFNVLAAAVDGLHPLHAMGDTPHGFSFFYGPMKRMMPNLWQDDGQPKPLRESKLQAAITFQFEHRRTLDKLDCTLPLANTIFQNGLHSTLLASRWRRPSNRAMPELLQIKEKQSQEVAYWPPKSALDVYVDSPIVPITVPREIVAGLGNIVSQISVQGQTMPASAELETAVNELYARRTKEGHEFPPGPVGVWAIVVPDGRFQKSNLKLLREWTGDLNRIQTAYDEWIEALAFKDLVQQLLRNGSRVYRILSGGGGWGKKQGLLSLDPETTYSSSSEEKDLESFIRSFESQHDGGGQQGVVSPGSWIQYFVSPPMSARPNPPRPHGATMEIALGASESATSEEPPSTDGPSEWKVIPEHFGAVSNHGLFLKREASGFVNESKLDVPGSWVGCLKLENP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6X0</accession>
    <name>E3Q6X0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ATP12 chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_02428</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATP12 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090628.1">
        <property type="nucleotide sequence ID" value="XM_008092437.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6X0"/>
    <dbReference type="STRING" id="645133.E3Q6X0"/>
    <dbReference type="GeneID" id="24407793"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02428"/>
    <dbReference type="eggNOG" id="KOG3015">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047893_1_1_1"/>
    <dbReference type="OrthoDB" id="5322896at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033615">
        <property type="term" value="P:mitochondrial proton-transporting ATP synthase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3580.10">
        <property type="entry name" value="ATP12 ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2180.10">
        <property type="entry name" value="ATP12-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011419">
        <property type="entry name" value="ATP12_ATP_synth-F1-assembly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042272">
        <property type="entry name" value="ATP12_ATP_synth-F1-assembly_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023335">
        <property type="entry name" value="ATP12_ortho_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21013:SF10">
        <property type="entry name" value="ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21013">
        <property type="entry name" value="ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 2/ATP12 PROTEIN, MITOCHONDRIAL PRECURSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07542">
        <property type="entry name" value="ATP12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160909">
        <property type="entry name" value="ATP12-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ26608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="384" mass="41783" checksum="2B458925F12F0D25" modified="2011-01-11" version="1">MKRSTRIPLRLFAASSPMTTAAGWPCFAAAAAAASRTISTTTLKPAEVAPVVGTGPPPEPPVPDLAAEDRAAAARARVERRKRQAEMLKHAKIIRTSAEAKASKPGALKRRFWNDVNVQEVDGALQVHLDNRPLRHPNTKEIMRLPVSKQHLASALAIEWDFITSAQQATKQHMIPLTSLTCRALDIAEDDAASGAIRQSIATTLMRYLDTDSLLCWAPPAGPLDTRNDAGESLRDVQKRTAEEVIGFLTARVWPGIEIHPVLDGHSIVPRAQAEGVREVVQGWVMGLDPWELTGLERAVLAGKSLITAARLVTEWSEGPVGECRDPESPRKFGIEEAATAASLEVSWQIGSWGEVEDTHDVEKEDLRRQLGSVVLLVSGTNRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7H3</accession>
    <name>E3Q7H3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_02631</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090831.1">
        <property type="nucleotide sequence ID" value="XM_008092640.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7H3"/>
    <dbReference type="STRING" id="645133.E3Q7H3"/>
    <dbReference type="GeneID" id="24407996"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02631"/>
    <dbReference type="eggNOG" id="KOG1269">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010595_7_1_1"/>
    <dbReference type="OrthoDB" id="184880at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF10">
        <property type="entry name" value="ABC TRANSMEMBRANE TYPE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ26811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="353" mass="39829" checksum="6A08A407318FA844" modified="2011-01-11" version="1">MSAEQQVSESTEATTQAEGSIEADSDELASIFDFDEASSSDGGYVTDSATNASTSIESSVRDYLYENGRRYHRFREGQYNFPNDEIEQEREDMKHAMVKLLCNQKLSFAPLGEWPQQILDMGTGTGAWAIEMGDRYPSATVLGVDLSPIQPEWVPPNVKFEVDDVESPWLYPANHFDYIHSRHTVMAIKDWEVLFQRAFEHLKAGGWIELQEIHHCPMSASNSLSATHPVARYWGNVVQGLSNLGIDLNAAAGERLPNMMREAGFINVTERVFHVPIGTWPRNRVLKTVGMYWRTILLDGLQAIALGPFTRGLQWSAEETELFLVDVRKAYHDTSALMYMPLRIMYAQKPTGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7J3</accession>
    <name>E3Q7J3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_02651</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090851.1">
        <property type="nucleotide sequence ID" value="XM_008092660.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7J3"/>
    <dbReference type="GeneID" id="24408016"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02651"/>
    <dbReference type="HOGENOM" id="CLU_1726617_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ26831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="152" mass="16898" checksum="031FA7507F40E9E7" modified="2011-01-11" version="1" fragment="single">NAFCILLTRAELLNITQTNQPGYTAGIQHLAQPTSFSGTFASSQRSIKKKEQGGGRELEAEHCDRSIACALYLAGRFCCGRQKKKDKKWWYSPKKSLFPKTNHPACNGLFVRIVRMVCMIAELCKLQSLHSDIGTTRKIFSAVPPISHKGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7N8</accession>
    <name>E3Q7N8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_02071</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ26900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090920.1">
        <property type="nucleotide sequence ID" value="XM_008092729.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7N8"/>
    <dbReference type="STRING" id="645133.E3Q7N8"/>
    <dbReference type="GeneID" id="24407436"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02071"/>
    <dbReference type="eggNOG" id="ENOG502SHVM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_3_7_1"/>
    <dbReference type="OrthoDB" id="5429740at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF155">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="38"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ26900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="277" mass="30500" checksum="F407A7BA389869A0" modified="2011-01-11" version="1">MPNPPKGSEAWKAQDRGPAIISVCWIFTALSSMFVLSRVYVRLRFVGRLYSDDYFIILGLICGYVSTSLSTLAVLSGTGRHLDVLTLEQQQNNMLWTTAAQCPGIMSFSLPKLAVISFLTRLLNPGVFHKWFLWWMGIWCQLTLVATVGLLIGRCTPARSLWDFSVAGTCFNPSVLINYSIYAGTFSAFVDVYLAVYPAIVLFKLQMRLKKKLALSCALGIGTVSGVVAIYKTTRLPLLASADYSCKCFSNLSLLLSMGTNTGDATDETPDLVVWTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q836</accession>
    <name>E3Q836_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_02219</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091068.1">
        <property type="nucleotide sequence ID" value="XM_008092877.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q836"/>
    <dbReference type="STRING" id="645133.E3Q836"/>
    <dbReference type="GeneID" id="24407584"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02219"/>
    <dbReference type="eggNOG" id="KOG4245">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039329_4_0_1"/>
    <dbReference type="OrthoDB" id="191270at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019748">
        <property type="term" value="P:secondary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000055">
        <property type="entry name" value="Uracil-5-carboxylate decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032465">
        <property type="entry name" value="ACMSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240">
        <property type="entry name" value="2-AMINO-3-CARBOXYLMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240:SF28">
        <property type="entry name" value="ISO-OROTATE DECARBOXYLASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="4">
        <location>
            <begin position="110"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ27048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="379" mass="41169" checksum="1B71E504426E3D45" modified="2011-01-11" version="1">MASSTTPMKVVDIHTHMYPPSYIKILESRTTIPVVRSFPQTPDPRLILLASEQQALDEATKDPSAKPPGRPLTSHYASLDQKVHFMDTHKIDISVVSLANPWLDFIDGSESGTMAKGVNDEFDAMCATQPGRLFFFATLPLTAPLETILAAINHVKDLKYCRGIILGTSGLGKGLDDPNLLPIFKAVAAAHLTIFLHPHYGLPNDVWGPRASNEYGHVLPLALGFPMETTIAVARMYLAGVFDAVPQLRMLLAHSGGTLPFLAGRIESCIMHDGQWVREGKVTEGRRTVWDVLKEQIYLDAVIYSEVGLKAAIEASGADRLMFGTDHPFFPPLTTDEQGEWESVSMNADAVAAAVGEGSDQAKAIMGGNAINILNLKVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q871</accession>
    <name>E3Q871_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tetratricopeptide</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_02254</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091103.1">
        <property type="nucleotide sequence ID" value="XM_008092912.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q871"/>
    <dbReference type="STRING" id="645133.E3Q871"/>
    <dbReference type="GeneID" id="24407619"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02254"/>
    <dbReference type="eggNOG" id="ENOG502R8TH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_762931_0_0_1"/>
    <dbReference type="OrthoDB" id="5379420at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ27083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="309" mass="35288" checksum="F1D03EB3EB235808" modified="2011-01-11" version="1">MTPDMLPTKVPVAPRSLSEFQILIKDLNMKHVAAQDAHDMYTKYMRAVADKQRPADTTASAAELHETAKIVLNLPALHESEFEFSCTMLRAAAGLGNDAAALSLGRILLRRTRARQNYFHWDNPWWRQARARCMALIEEGRDANALVLKGLIHMKRNNPRDDSLALEAFAQAETVGKSADRFDWEPTCLEGQGNAHQRLDQKEQAEEAFRRLADLDCAEGFYHLARLLPRSESTLEWLTKAAASGLRETYQLLVDEHERLRSICMNQGREKEARRHERDAAEWTLIMRAQATRKKELNTATEPMRNQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8B0</accession>
    <name>E3Q8B0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fatty acid hydroxylase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_02293</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091142.1">
        <property type="nucleotide sequence ID" value="XM_008092951.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8B0"/>
    <dbReference type="STRING" id="645133.E3Q8B0"/>
    <dbReference type="GeneID" id="24407658"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02293"/>
    <dbReference type="eggNOG" id="KOG0874">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043293_0_1_1"/>
    <dbReference type="OrthoDB" id="408954at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102772">
        <property type="term" value="F:sphingolipid C4-monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042284">
        <property type="term" value="F:sphingolipid delta-4 desaturase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051999">
        <property type="term" value="P:mannosyl-inositol phosphorylceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050307">
        <property type="entry name" value="Sterol_Desaturase_Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11863">
        <property type="entry name" value="STEROL DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="191"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="6">
        <location>
            <begin position="204"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ27122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="363" mass="41360" checksum="8C67B92E92BB03EA" modified="2011-01-11" version="1">MATNFTSMAGDLPPLPAYTLKPYADMIPGLPDVYLRIFLPIVVYWVLSLFFHVIDVYDIWPQYRLHTPEEITKRNHVSRYEVARDVVLQQLIQISMSVFLEYIDEEQLTGREDYDVAVWATRVRIAQRALPTFLGLLGLNAASISKNMSASHPFIAGALAGGHYPFLTTELDGSHTVVPAFASWELLVAKAIYWLVIPGLQLFAAISILDTWQYFLHRLMHVNKWMYTTFHSRHHRLYVPYAFGALYNHPFEGFLLDTLGAGISFLITGMSGRQGLLFFCLSTVKTVDDHCGYSLPWDPLQHITSNNAAYHDIHHQTWGIKTNFSQPFFIFWDRALDTRYKGDRQNRILAAKGKVAAVGAKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8Z5</accession>
    <name>E3Q8Z5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Mitochondrial carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_02004</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091529.1">
        <property type="nucleotide sequence ID" value="XM_008093338.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8Z5"/>
    <dbReference type="STRING" id="645133.E3Q8Z5"/>
    <dbReference type="GeneID" id="24407369"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02004"/>
    <dbReference type="eggNOG" id="KOG0758">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_16_2_1"/>
    <dbReference type="OrthoDB" id="409586at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000064">
        <property type="term" value="F:L-ornithine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990575">
        <property type="term" value="P:mitochondrial L-ornithine transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF12">
        <property type="entry name" value="MITOCHONDRIAL ORNITHINE TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="18"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="114"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="216"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ27509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="305" mass="32671" checksum="5EE14AEB64D61507" modified="2011-01-11" version="1">MADAVVDPEVAGGALQTVKDLAAGAAGGVAQVLLGQPFDIVKVRLQTSTTSSSALTAASQIYKNEGALAFYKGTLTPLIGIGACVSIQFGAFHQARRYFEARNAASSLGASPALSYGQYYAAGAFAGVANSVISGPIEHVRIRLQTQPHGAARLYSGPLDCVRKLSSHGGVLNGLYRGEAVTILREAQAYGVWFLAFEWMMNADAARNKIDRKDIPSYKIAFYGGLAGEALWLSSYPFDVIKSKMQTDGFGKEQRYKTMRDCFAQTYRGEGLRGFWRGIVPTLLRAMPVSAGTFATVELAMRALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q906</accession>
    <name>E3Q906_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">2,3-bisphosphoglycerate-independent phosphoglycerate mutase</fullName>
            <ecNumber evidence="6">5.4.2.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Cofactor-independent phosphoglycerate mutase homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">GLRG_02015</name>
    </gene>
    <organism evidence="19">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate</text>
            <dbReference type="Rhea" id="RHEA:15901"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="EC" id="5.4.2.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the BPG-independent phosphoglycerate mutase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.12" evidence="6"/>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091540.1">
        <property type="nucleotide sequence ID" value="XM_008093349.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q906"/>
    <dbReference type="STRING" id="645133.E3Q906"/>
    <dbReference type="GeneID" id="24407380"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02015"/>
    <dbReference type="eggNOG" id="KOG4513">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026099_2_0_1"/>
    <dbReference type="OrthoDB" id="1886626at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00186"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004619">
        <property type="term" value="F:phosphoglycerate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006007">
        <property type="term" value="P:glucose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16010">
        <property type="entry name" value="iPGM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1450.10:FF:000001">
        <property type="entry name" value="2,3-bisphosphoglycerate-independent phosphoglycerate mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1450.10">
        <property type="entry name" value="BPG-independent phosphoglycerate mutase, domain B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01038">
        <property type="entry name" value="GpmI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011258">
        <property type="entry name" value="BPG-indep_PGM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006124">
        <property type="entry name" value="Metalloenzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036646">
        <property type="entry name" value="PGAM_B_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005995">
        <property type="entry name" value="Pgm_bpd_ind"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01307">
        <property type="entry name" value="pgm_bpd_ind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31637">
        <property type="entry name" value="2,3-BISPHOSPHOGLYCERATE-INDEPENDENT PHOSPHOGLYCERATE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31637:SF0">
        <property type="entry name" value="2,3-BISPHOSPHOGLYCERATE-INDEPENDENT PHOSPHOGLYCERATE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06415">
        <property type="entry name" value="iPGM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01676">
        <property type="entry name" value="Metalloenzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001492">
        <property type="entry name" value="IPGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64158">
        <property type="entry name" value="2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9 15" id="KW-0464">Manganese</keyword>
    <keyword evidence="7 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metalloenzyme" evidence="16">
        <location>
            <begin position="7"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="BPG-independent PGAM N-terminal" evidence="17">
        <location>
            <begin position="88"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphoserine intermediate" evidence="13">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="159"/>
            <end position="160"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="266"/>
            <end position="269"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="340"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="412"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="416"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="453"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="454"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="471"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00071648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00083354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001492-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001492-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR001492-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF06415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EFQ27520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="524" mass="57507" checksum="D96481C62B9CB5AD" modified="2011-01-11" version="1">MAQTEQKACLIVIDGWGVPGADSPKDGDAITNAKTPVMDAFAQSKTGYCELEASSLAVGLPEGLMGNSEVGHLNIGAGRVVWQDVVRIDQTIKEGKFAENDVIKKTFEGARDGNGRLHLCGLVSHGGVHAKQVHLYNLLKAAKQYGVPKVYIHFFGDGRDVDPKSGADYMEELIKTAGEIGTGEIATVVGRYYAMDRDKRWERVQIALDGMINGKGEESSDPVKTVRERYARGGDKDKDEFLTPIIVGGDERRIKDDDTVFFFNYRSDRVRQITQLLGDVDRSVLPDFNYPKIRTLVTMTQYKVDYPFEVAFKPQHMGNVLAEWLGKQGVEQVHIAETEKYAHVTFFFNGGVEKVFALETRDESQDLVPSNKAVATYDKAPEMSADGVANQVAKRLGEQKFPFVMNNFAPPDMVGHTGVYEAAIVGVEATDKAIGKIYDACKKQNYILFITADHGNAEEMKFPDGKPKTSHTTNKVPFIMANAPEGWSLKKDGGVLGDVAPTVLAAMGLPQPEEMTGTNLLTKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q950</accession>
    <name>E3Q950_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Oxidoreductase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_01724</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091249.1">
        <property type="nucleotide sequence ID" value="XM_008093058.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q950"/>
    <dbReference type="STRING" id="645133.E3Q950"/>
    <dbReference type="GeneID" id="24407089"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01724"/>
    <dbReference type="eggNOG" id="ENOG502SD1F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015711_1_0_1"/>
    <dbReference type="OrthoDB" id="5426191at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="378"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="419"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="568"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="381"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="454"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="634" mass="68978" checksum="06652B3488797B34" modified="2011-01-11" version="1">MSTNIEARSLASLNYLAANPPQYPHKPADQRQDPLTLYISRVPGTRDVILTTSKPHPKNVTSEDVANSFYYIHLELPNDGGRPYNPIQAHQAAAQAHHLRNPDTPRSSQDSTRSANQIRRKPLPTGAKVPSPPADPARSQLPPNLPPAPASSHPAAAGNGGYGYGSGYVPGADPRQPRSTEDRPDLPPRPTSNSPPMPVRKPVGARGTPAPAPDSATPSSVQPHDPHRASPSHETSHVPDEPTSPARSRRWSRTPAGSSIFRQQSRSPSPNRFHNTTAVPYTLSLIRRDPGSGNQWNIGRVSSHQLEDAGDDGYEYLSFDSAGLSAHERRRANAPQPPINIRLESSGYAKFRHMPLRQSVDMARNSSSSLPFANSEDALHQLQQQQQQQQQQQRQSSEGGFSRQVVMAYAKSWSSNIREKLSSRSRSGSVDDGGGLTVPGSPPERSKRHIRQLSANSTGSVSSNGSDSGPIITQPGHGLRPRGYVFISPWDGRCEFRTGNAGRSVKCRHLLPMAGGLSNPLAPTGSSTYSAVVSELRFNLPSTELFRQEGKREQLSGHFSRLLKVGNRDGEYSDDDDPPSPFDLKLGKERAGGGNRGKRAKLGKLIIYPEGLKMLDLVVAANMGVWWGAWEKSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q957</accession>
    <name>E3Q957_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_01731</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091256.1">
        <property type="nucleotide sequence ID" value="XM_008093065.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q957"/>
    <dbReference type="GeneID" id="24407096"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01731"/>
    <dbReference type="HOGENOM" id="CLU_2654343_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ27236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="76" mass="8376" checksum="A81285BB6FECEFAE" modified="2011-01-11" version="1">MQNGPCGWRLQSLPDGFAPTTLPVRAPRHRGATISGARGSCGEEVQSKLRFLEALTYFWLLMVSAQRRRATMGAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9N2</accession>
    <name>E3Q9N2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bin/amphiphysin/Rvs domain for vesicular trafficking</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_02714</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091590.1">
        <property type="nucleotide sequence ID" value="XM_008093399.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9N2"/>
    <dbReference type="STRING" id="645133.E3Q9N2"/>
    <dbReference type="GeneID" id="24408079"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02714"/>
    <dbReference type="eggNOG" id="ENOG502QQ2V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059017_0_0_1"/>
    <dbReference type="OrthoDB" id="5549748at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07600">
        <property type="entry name" value="BAR_Gvp36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018859">
        <property type="entry name" value="BAR_dom-cont"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10455">
        <property type="entry name" value="BAR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00721">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BAR" evidence="2">
        <location>
            <begin position="9"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ27570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="321" mass="35525" checksum="B313D8161AE054AD" modified="2011-01-11" version="1">MDFKNFGKNITSFGASITPFASRTFQYTKEQLGQAEDKTQLPPDYIDLEKRVDALKQVHQKMLAVTSQYSNEAYDYPPNLKETFQDLGRTVSEKVSLLSSAASPAEAQAALTAPPTAKPQPKTFNHAIARASLSSSQVLHQQHTGAGEDPLATALEKYALAMERVGEARMAQDAQIQSRFLAGWNTTLNTNLKFATRARQNVEKSRLTLDAAKARAHGTTWKIGPGSPRPDEHQPQELSPEAQEEIEKAEDEFVTQTEEAVGVMKNVLDTPEPLRNLADLIAAQIEYHKRAYEILSELAPVVDGLQVEQEASYRKSRENAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9S1</accession>
    <name>E3Q9S1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mitochondrial K+-H+ exchange-related-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_02753</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091629.1">
        <property type="nucleotide sequence ID" value="XM_008093438.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9S1"/>
    <dbReference type="GeneID" id="24408118"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02753"/>
    <dbReference type="eggNOG" id="KOG4539">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043838_2_0_1"/>
    <dbReference type="OrthoDB" id="5562676at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018786">
        <property type="entry name" value="Mit_KHE1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28062">
        <property type="entry name" value="K+-H+ EXCHANGE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28062:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10173">
        <property type="entry name" value="Mit_KHE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ27609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="297" mass="33398" checksum="7C6E9E7E0D600D85" modified="2011-01-11" version="1">MRLYLLPLTTSRTLLYAQRLNVATNSQQGLADKVGKKAAKLWAGWEARESGWQKKVVNYGNYALRRIPYEEWGLKSVPPISARRKDDELKGNEKIELVFPDKVIPTGKAEQVVRTLAKERDALHKRKLIWCLIGMPISAPFALVPVIPNLPFFYLAYRAWSHWRALEGGKHLRFLVDNKLLALSPSKLLNDIYTPLIPKNTTQTPSKPALGQSEPLQGKAENAEDEAILLSQANGQRIAKVLDVPELAVEIERAIWQVNHAKQANQEEVTDDAAKQANAEPPKDKRNPAAPPDNEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAI8</accession>
    <name>E3QAI8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_03020</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ27876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091896.1">
        <property type="nucleotide sequence ID" value="XM_008093705.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAI8"/>
    <dbReference type="GeneID" id="24408385"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03020"/>
    <dbReference type="eggNOG" id="KOG0256">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_624043_0_0_1"/>
    <dbReference type="OrthoDB" id="4846323at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="331"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="404"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="444" mass="50614" checksum="17BBCC411EE560ED" modified="2011-01-11" version="1">MNDHGRKLSWTAQLSPYLRGLKMKNIMPSPKPSKSPKSPKPPRNFREDDSGFRITHTPDRPERPISRTAIPTDEQCMEFLMSLQRQEEHRRGSTKSGLKMWPNSQEDDPEDRRYLRSVRVESVQFEEARLARTNSFGPARVVDVGRSSTKSTLATPGVSDKGEEEEGDEDDDDDDNESIVEPKRCTDAALSPPPTLYRNKPYLEVHTPRANTSRWSDDSLESRLSSREHDSPCVQRCQRVTLRSSTEASSSPTVFGDDSMEPSTPSPLTPVKIRPATPFTDSQLRAETDPITPPPSDQVAHLMHISPEPVPREYSWRSSRDTVLNAEAPASKASAWLPEPWPREEVKNQKQGSEPEVYGDWADYYFEDGNFWDGYSEEDDTRVEGESDADDERNEHGTDEEDQKEEKEEDQKGRRQADGEVYPRYESFIEDYKKNIMSITVTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAS8</accession>
    <name>E3QAS8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_03110</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ27966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091986.1">
        <property type="nucleotide sequence ID" value="XM_008093795.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAS8"/>
    <dbReference type="STRING" id="645133.E3QAS8"/>
    <dbReference type="GeneID" id="24408475"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03110"/>
    <dbReference type="eggNOG" id="KOG2852">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007884_14_0_1"/>
    <dbReference type="OrthoDB" id="498204at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847:SF150">
        <property type="entry name" value="OXIDOREDUCTASE TDA3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="2">
        <location>
            <begin position="55"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ27966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="476" mass="51335" checksum="127A7D43FF185869" modified="2011-01-11" version="1">MPAVGKKAKAKTKTKTKTKKQRREKSLQLAAARIIKEALIPPSLPVMDPQAKRNIVIVGGGIIGSTTAYFLTRHPKYNPALHRITLLEATAVASGASGKAGGLLALWAYPQCLVPLSYRLHKELAAEHGGEKRWGYRRVNCGSFEARVTKQMLERPRQAVAKPEAVAPGANDGEQEKGWERLPKQDDAAEAMLEESVLPRDLDWVDRDAVESYAEMGMPGATETAQVHPYLFTTSMAALAQDKGVEIRTNAQLTAIASSGEGVTGVEYLDRESGETCTIEGVTDVLVSAGPWTGRLLPASKVTGLRAHSVVYNANVSPYAVFTSIKLPADFVPEHRASKGQKRKHKRVVDPEIYARPDGEVYACGEPDENAPLPETADKVQVDEANCDDIISYIATVSPVLVAAPIKAKQACYLPQHDSGPLIGATSVPGLWLAAGHTCWGIQNGPATGKLMSEYILDGKPTSSDISSLDPRRFKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAT9</accession>
    <name>E3QAT9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">3-hydroxyacyl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_03121</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ27977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091997.1">
        <property type="nucleotide sequence ID" value="XM_008093806.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAT9"/>
    <dbReference type="STRING" id="645133.E3QAT9"/>
    <dbReference type="GeneID" id="24408486"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03121"/>
    <dbReference type="eggNOG" id="KOG2304">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_2_0_1"/>
    <dbReference type="OrthoDB" id="5958943at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000009">
        <property type="entry name" value="Fatty oxidation complex, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022694">
        <property type="entry name" value="3-OHacyl-CoA_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006180">
        <property type="entry name" value="3-OHacyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006176">
        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48075">
        <property type="entry name" value="3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48075:SF5">
        <property type="entry name" value="3-HYDROXYBUTYRYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02737">
        <property type="entry name" value="3HCDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000105">
        <property type="entry name" value="HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00067">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3-hydroxyacyl-CoA dehydrogenase NAD binding" evidence="7">
        <location>
            <begin position="37"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="3-hydroxyacyl-CoA dehydrogenase C-terminal" evidence="6">
        <location>
            <begin position="225"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="41"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="4">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000105-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000105-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ27977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="321" mass="34010" checksum="833738E5D24DC462" modified="2011-01-11" version="1">MTTAIARVRAVTKLPGQLRAFSSTSAVASATGGVKRLGVIGAGQMGLGIALVAAQRAQVPVTLIDANKAALDKGISFAEKLLAKDVSKSRITQEQADQARSLISPNTSIDALSDVDFVIEAVPEIPNLKFEIFAKLAEICPKHAILATNTSSISITRIAASTTKDPTDTSASSRVVSTHFMNPVPVQKGVEIISGLQTSQETLDKAVAFCKAMGKITSVSADSPGFLANRILMPYINEAIICLETGVGDKESIDSIMKNGTNVPMGPLQLADFIGLDTCLAIMKVLYEETGDSKYRPSVLLRKMVDAGWLGKKSGKGFYDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAY1</accession>
    <name>E3QAY1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NDT80/PhoG like DNA-binding family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_03163</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ28019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092039.1">
        <property type="nucleotide sequence ID" value="XM_008093848.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAY1"/>
    <dbReference type="STRING" id="645133.E3QAY1"/>
    <dbReference type="GeneID" id="24408528"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03163"/>
    <dbReference type="eggNOG" id="ENOG502SAHY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019835_1_0_1"/>
    <dbReference type="OrthoDB" id="4117572at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000228">
        <property type="term" value="C:nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1390">
        <property type="entry name" value="NDT80 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052605">
        <property type="entry name" value="Fungal_trans_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024061">
        <property type="entry name" value="NDT80_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037141">
        <property type="entry name" value="NDT80_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008967">
        <property type="entry name" value="p53-like_TF_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35144">
        <property type="entry name" value="MEIOSIS-SPECIFIC TRANSCRIPTION FACTOR NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35144:SF4">
        <property type="entry name" value="TRANSCRIPTION FACTOR VIB-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05224">
        <property type="entry name" value="NDT80_PhoG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49417">
        <property type="entry name" value="p53-like transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51517">
        <property type="entry name" value="NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NDT80" evidence="4">
        <location>
            <begin position="101"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="NDT80" evidence="2">
        <location>
            <begin position="101"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="24"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="486"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="28"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="497"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ28019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="657" mass="70813" checksum="340636563A87531C" modified="2011-01-11" version="1">MAELKEPAHSNLWSNYGSPVQMSRFNNSLDSGLGGHSSSSPHAGRPRSTHPSVDHGSYPYGRYPQDESDAYDRHSHPSLTSHHSFPNLKRPYSQTEQPPYQEIVQDLRDDGSKLTVNHDHKLLSFKRVQDKHTIVDQHGRMQQLELSAQLHGMFFLSEMPSNSTDGSILQPELTCYRRNLFQISGSLITPRGQLSVITETGETAPVSNTEVTISAIESVDGHPVRLIVIPWKTPPPNSPELTQNPDQEPASLPLIPFQDDGSETEGDYAVYPIGWRRLQFRIATANNGRRKELQQHFVLHLKVVGTLANGSKVVLTEATTAPIVVRGRSPRNFQARKEIPLLGSSAGSRGQALVETGLGIVAGPLAIKPQDAKARGLDMQMPRSAFTFSAGGPKMPGAPMGAMRSNSYPNWSSSNPVSISQLPPAGSGSYPATTMGAEPYHKLPLSGGSSFGAEPQDMPLQTSMPSMQLSLAANEQPPIRTQYAYVQSTTGPPPVSVSATAMAPSSDNALSVPRYVDNPRPTKSPRHASQPSIGPMSHHEASPEYRYGSSYGAVGNNPSDIAPPAYKTEAPSSHSGPARDYYPPSSSWTTTAGEPASTVAYSSSEGRPYGFPDHYSSAGPAPTPKHEHGPAPPAPGSYSSAHRGSFDGMNHYSWNAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>E3QB41</accession>
    <name>E3QB41_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">SNF2 family domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_03223</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ28079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092099.1">
        <property type="nucleotide sequence ID" value="XM_008093908.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QB41"/>
    <dbReference type="GeneID" id="24408588"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03223"/>
    <dbReference type="eggNOG" id="KOG0298">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001592_2_0_1"/>
    <dbReference type="OrthoDB" id="5330228at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18070">
        <property type="entry name" value="DEXQc_SHPRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000059">
        <property type="entry name" value="SNF2 family helicase/ATPase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052583">
        <property type="entry name" value="ATP-helicase/E3_Ub-Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059033">
        <property type="entry name" value="C144_05_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45865:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SHPRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45865">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SHPRH FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26021">
        <property type="entry name" value="Ferritin_C144_05"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="334"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="1133"/>
            <end position="1171"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="1242"/>
            <end position="1397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="736"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="736"/>
            <end position="745"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ28079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1457" mass="163992" checksum="15105E406058E681" modified="2011-01-11" version="1">MGRSKSMARRSKAIPEITTIGFHEPWPIGFINQLHALLTDSEDQSHGKGVAEPPSKRVKRYDGDAEALLLAKEELELVRKCPEGVLVNGPQPVCRRNIGSYLRFWLSQSKGVGIAARPRTDVLPINATVAIQPNIMNNRLAACLDVYACHWTKALGEGELWVSLDATASTQGGFYKVSFCFNLYWNETKSPYSRLRSSVERKLSQRVLNIFLPDVVSSSSTNRGLESWSPLDFYEAAHVPAADDRTALSIEVPELTASLYPYQKKTVQWLLKREGVRWNGSNTGSLPSIEDLQHPHEVDDAHSFRETRDELGTGRSFYVSNLYHVVTTDLGPFQHAEQSVRGGILAEEMGLGKTIEIIGLIALHRRPPADDVVHTTDGEELLTTGATLIVTPDSLKQQWIEELERHAPHLQVKYYPGRKNVNFDTEEELRADLAFHDVVITTYPVLSAEVHFAMKAPERSRRQERKYERAGSPLTKISWWRVCLDEAQMIESGVTGAAAVARLLPRINAWGVTGTPVKNDVKDLYGLLDFLRYEPYASSPQVWRSLTESQKPLFRSLFGRIALRHTKQLVRHEIVVPPQKRFVITLPFTAVEEQYYSEMFKNMARRCGVDLLGAPLQADWVPEDYENEMRTWLNRLRQAALHPEIVQRRGTGRKVGPMRTVEEVLDAMIEQSDNDIRTDHRAYLQARLTHGQMLENGPRVKEALEIWERVKKDAAVLVVECRQELKAILDEVATMRRSTTSGQTQEAGDDASASGDIDEDGGDDGANNPRVGEARAKLRHALEVLHKATFFCANAFFQIKSDTDMTEPDSDQFKKLQQLEDSEYGKAQEIRREILSESHAKAMSLIKRLERQAQSQSFVEIPELVFKEMRGLESGPTLEMLEELYAILNEQANRIDEWREAVIKLLCQPLIDEEAEAEVTGEEFTDSTRIQEELIVYVQILRAAIADRQEAISGLGNALVKHEMRVSLAAAEDGDGPAPEKLLALYRLRDEVKPSPDKHGSLRRVIANLRAIASRLPKDGTGGRADTEREIVYRQIRATQAHITSQTKAATALEREVDRFTNAMNARVEYYRQLQAVSDSVAPYEGPNDDKAIAACVVNEERQHNKLDSARAKHRYLLNLKSEGGQSNEPRWCIICQAYFTTGILTICGHEFCRDCLKQWYRAHHNCPMCKRTLRLTELHDITLQPRELKMHEDTAIDPSPEGKKNQAAKASGIYSHFSSEKLAQINDVELGSLSFGTKVDTLVRHVLWLRESDPGAKSIVFTQYKSFLEILGAAFDRYKIGFSTIDRPNGITRFKEDPGVECFMLHGRANSSGLNLVNASHVFLCEPLLNTALELQAIARVDRIGQKNETTVWLYLIEGSVEESIYNLSVKRRMEHMGQSSKAKSKESSPEVQEPTLEAANTLELEQASLNRLMSRDKNAGEAVAAEDLWECLFGQVSRRITSGVTGSITQGEDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBH2</accession>
    <name>E3QBH2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_03455</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092331.1">
        <property type="nucleotide sequence ID" value="XM_008094140.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBH2"/>
    <dbReference type="STRING" id="645133.E3QBH2"/>
    <dbReference type="GeneID" id="24408820"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03455"/>
    <dbReference type="eggNOG" id="ENOG502SHVI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007426_4_0_1"/>
    <dbReference type="OrthoDB" id="4934715at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF49">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="35"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="147"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="440"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="161"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="174"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="440"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ28311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="785" mass="86661" checksum="7F88E9E2C64F86D5" modified="2011-01-11" version="1">MSSSSDITHFTSVFRAQSLSDQQRRVAKRNRQPVSCLACRTRKLRCDRALPCGACAKRGDGDACQFGTAVPLNGGNRNGAGGHAGMGAVDRENGVAVAPSTPGYRPGESGNRGGGASRQQQQQLLLRRPEVQLRLQKLEDMVRDLVRNSASASQARDRIGPAPTKPTTVPTPTDSEPGNRGNSPVLTPPEGGYDYYGATHWTALLHHIREIQTALEPDPTALPEPPEGGACSMSPDVLFGAVVTVSMPEVLYSLPPRQDLDKLLAVYFNARSTAVPFIHVGRFQREYEAFWEKPEAAGFLWISIIFSIISIAVIIVRGKGTVETLGLTRDLKEPSAYAGRAVQCLVKGNYLVAKKYSVEATILVAYTRVIGSKDMDPILSNLFGVATRLAQRRGYHLDPKHLSTPISPFEAEMRRRAWFYCESFDLLLSFQLGMPAIVHESDSDTRGPENHPDEDFDEDTVTMPPPRPPTEPTPILYYCLKSKLCRILRKVIRHALSPTQPVYAETCVLNDALHAWYAELPAAMRVRPIRATGFTEQNYTVMQRLMLELTYRKALCVLHRTYLSRDKADPRFALSREICRAAALTILNLHAEFDRESSPGGRLFEDRYMLSSLMLHNFMIAAMVVCLDLNENTDMSDEDYERKMNALKTASEIWSNRASCSRDARHASTVLRAMVQRLTSRRRRISQRQGEGLTTVAASGVDVCGDGNEIPASSFFEAPTTDSGFGDVGGGGNGQPQGVGMDQAFDFDFMTLDNALNDPYNLDWGLLDQYLTLDGNGQLAMDVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBX9</accession>
    <name>E3QBX9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GMC oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_03358</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092234.1">
        <property type="nucleotide sequence ID" value="XM_008094043.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBX9"/>
    <dbReference type="STRING" id="645133.E3QBX9"/>
    <dbReference type="GeneID" id="24408723"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03358"/>
    <dbReference type="eggNOG" id="KOG1238">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002865_7_1_1"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.410.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF152">
        <property type="entry name" value="OXIDASE (CODA), PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04090)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="3">
        <location>
            <begin position="264"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ28214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="550" mass="60926" checksum="A3675D0830A65823" modified="2011-01-11" version="1">MSTTQLPASDVDRYDYVIVGGGTAGCVVASRLAESLPQKRVLLIEAGPSDFMDDRVLDLRKWLNLLGGELDYDYGTTEQPMGNSHIRHSRAKVLGGCSSHNTLISFRPFEYDLKIWQSMGAKGWTFHDFMRIMDKLRNTVQPVHARHQNELCLDWVNSCSSALDIPVLHNFNKHITQNGALKQGVGFFSISYNPDDGRRSSASVAYIHPFLRGEEKRPNLTVLTNAWVSKINVRGDTVTGVNLTLQDGSKRTVTARAETVLCAGAVDTPRLMLLSGIGPKQQLVDLGIPVIHDLPGVGENLQDHPESIIMWELKKPVPPNQTTMDSDAGIFLRREPPNAAAKKTFFNPDGIPDGDIADVMMHCYQIPFTLNTARLGYDEPKDGYAFCMTPNIPRPRSRGRLYLTSADPSVKPALDFRYFTDEEGYDAATLVYGMRAARKVAEQAPFKDWIAREVAPGPAVQTDEELSLYARRAAHTVYHPVGTTKMGDVRKDPLAVVDERLNVKGLKRVRIVDAGIFPTIPTINPMLTVLGVAEKAAEMIIDEAQETARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QE01</accession>
    <name>E3QE01_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04233</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093109.1">
        <property type="nucleotide sequence ID" value="XM_008094918.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QE01"/>
    <dbReference type="STRING" id="645133.E3QE01"/>
    <dbReference type="GeneID" id="24409598"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04233"/>
    <dbReference type="eggNOG" id="ENOG502S8MB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080764_1_0_1"/>
    <dbReference type="OrthoDB" id="5397701at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37331">
        <property type="entry name" value="YALI0F11671P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37331:SF1">
        <property type="entry name" value="YALI0F11671P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="233" mass="24420" checksum="A280F1FED9E73873" modified="2011-01-11" version="1">MLAPTARFSPRLASRSIFFRSVSSLSSNPRIKVFPADASRASFLLSYLEDDPPNQRLAIGFSTTDPPSPRSFTENQTFTKILYEVLSENAHKDKDLLAQAQAFASPGGATLGSGGAFFSQKNKQRSSSKVGGGGGAGGSGAGGASAQGGAGGGGHGGYVHLSDSRNPPDFGRIAWPEDIMGSVEVDQSGNIIGQLEPSGTYRIITNEGILGLSPFLEEKLIARLRAENKKDKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEB0</accession>
    <name>E3QEB0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Transient receptor potential ion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_04342</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transient receptor potential (TRP) ion channel family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093218.1">
        <property type="nucleotide sequence ID" value="XM_008095027.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEB0"/>
    <dbReference type="STRING" id="645133.E3QEB0"/>
    <dbReference type="GeneID" id="24409707"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04342"/>
    <dbReference type="eggNOG" id="ENOG502QSVZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010226_1_0_1"/>
    <dbReference type="OrthoDB" id="5212126at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009272">
        <property type="term" value="P:fungal-type cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010308">
        <property type="entry name" value="TRP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040241">
        <property type="entry name" value="TRP_Flc/Pkd2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032800">
        <property type="entry name" value="TRP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31145:SF2">
        <property type="entry name" value="FLAVIN CARRIER PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31145">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_7G01610)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06011">
        <property type="entry name" value="TRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14558">
        <property type="entry name" value="TRP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01320">
        <property type="entry name" value="TRP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180355" evidence="9">
        <location>
            <begin position="26"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="335"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="378"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="418"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="478"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="505"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="535"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="566"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="domain" description="ML-like" evidence="10">
        <location>
            <begin position="28"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="641"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="671"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="725"/>
            <end position="741"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ29198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="758" mass="82800" checksum="E566ED7C20145B03" modified="2011-01-11" version="1">MRLSFAKPLLLLGSLAAYLTTPVMAAEQLLQSNSLNTCQDDSSFTASLFNVIFTPTNGSAAINIVAVSSVQGSIVFDISISAYGYEFLRRTVDPCSINLAGLCPMTAGKITMNFNLPVSQEAVSQIPGIAYNIPDLDATVRVFVNLTNTDQSVACVEADISNGKTVDLIGVKWATAIIAGLGLISSAVISGLGHTNTAAHVAANTLSLFGYFQSQAIVGLTGVHLPPIVQSWTQDFVWSMGIIRLQFMQDIFTWYQRATGGTPSTLLNSLTTTSVQVEKRSLDWGLSAARMARRGIEAGASIIAKRANIQLSSGSFIVFGIQRVAFRAKIESTNLFMTGLSFFCVFVIFTVLGVAAFKGFCELAVRQKWMKSEKFLEFRNGWFTVLKGILFRMTLIGFPQMSILCLWEFTQVDSAAEVVLAVFFLFGMAITLGWASFKVIRIARRSVVMHRNPAYILFSDPQALNKWGFLYVQFRASAYYFIVPMLGYTVVKGMFVAFAQRSGTVQAISFVIIEAAALIAASVLRPWMDKSTNSFNIAICVMNFLNAIFLLIFSDVFGAPPLVNGIVGVVLFIANAAFALILLLLVIVSSTLIYFRKNPDARYQYMADDRASFMKSQTQLHTTTELDALAATARGDKAHYKKGLDLDDDNDSISSESMRRRVDPSGAPVPQSTTQSASQSQQSMQRPGGPNGQVQSPVDPSTPLFPVDNRNPYGQAPMRTPSPYNGNPNQQRQQNNSSPGQLRTQNNVSPWQRGAGYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEI4</accession>
    <name>E3QEI4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">superoxide dismutase</fullName>
            <ecNumber evidence="4">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_04434</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>2 superoxide + 2 H(+) = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell envelope</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Cu-Zn superoxide dismutase family.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="4"/>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093310.1">
        <property type="nucleotide sequence ID" value="XM_008095119.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEI4"/>
    <dbReference type="STRING" id="645133.E3QEI4"/>
    <dbReference type="GeneID" id="24409799"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04434"/>
    <dbReference type="eggNOG" id="ENOG502RZIM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063073_0_0_1"/>
    <dbReference type="OrthoDB" id="159229at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.200:FF:000007">
        <property type="entry name" value="Cell surface Cu-only superoxide dismutase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.200">
        <property type="entry name" value="Superoxide dismutase, copper/zinc binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036423">
        <property type="entry name" value="SOD-like_Cu/Zn_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49329">
        <property type="entry name" value="Cu,Zn superoxide dismutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178414" description="superoxide dismutase" evidence="9">
        <location>
            <begin position="21"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ29290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="245" mass="25358" checksum="4ADC913950D7D449" modified="2011-01-11" version="1">MKASSIISVIAAAAFGRVAAETGALGDALIMSNPPGVVYEAILPETPFFKAGSLDGNVKGSIVAITAPDGKGVEFKVRFSNLPKEGGPFSYHIHVDPVPADGNCTKTLAHQDPFIRGEVTPCDASKPETCQVGDLSGKHGAVTADYEKTYIDSFVSIAEGPGSFFGNRSFVFHFANKTRISCANFKLVTKPDTHDNCTSTTPGPTGCPPVATASPTPVPFPGAAYTSGASISLMLAGFAAVVFVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEI9</accession>
    <name>E3QEI9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Protein phosphatase methylesterase 1</fullName>
            <shortName evidence="7">PME-1</shortName>
            <ecNumber evidence="7">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_04439</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Demethylates proteins that have been reversibly carboxymethylated. Demethylates the phosphatase PP2A catalytic subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>[phosphatase 2A protein]-C-terminal L-leucine methyl ester + H2O = [phosphatase 2A protein]-C-terminal L-leucine + methanol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48548"/>
            <dbReference type="Rhea" id="RHEA-COMP:12134"/>
            <dbReference type="Rhea" id="RHEA-COMP:12135"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17790"/>
            <dbReference type="ChEBI" id="CHEBI:90516"/>
            <dbReference type="ChEBI" id="CHEBI:90517"/>
            <dbReference type="EC" id="3.1.1.89"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the AB hydrolase superfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="7"/>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093315.1">
        <property type="nucleotide sequence ID" value="XM_008095124.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEI9"/>
    <dbReference type="STRING" id="645133.E3QEI9"/>
    <dbReference type="ESTHER" id="colgm-e3qei9">
        <property type="family name" value="PPase_methylesterase_euk"/>
    </dbReference>
    <dbReference type="GeneID" id="24409804"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04439"/>
    <dbReference type="eggNOG" id="KOG2564">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024818_3_0_1"/>
    <dbReference type="OrthoDB" id="194865at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051723">
        <property type="term" value="F:protein methylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000186">
        <property type="entry name" value="Protein phosphatase methylesterase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016812">
        <property type="entry name" value="PPase_methylesterase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14189:SF0">
        <property type="entry name" value="PROTEIN PHOSPHATASE METHYLESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14189">
        <property type="entry name" value="PROTEIN PHOSPHATASE METHYLESTERASE-1 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF022950">
        <property type="entry name" value="PPase_methylesterase_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0719">Serine esterase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="10">
        <location>
            <begin position="126"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="210"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="236"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR022950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR022950-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ29295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="408" mass="44549" checksum="0D4A5867ADA4714A" modified="2011-01-11" version="1">MSELQRAWAKRKLDPMHPLPEPLNDLDEESEVDQLPELPEHMDDGDSSSASSASSASSTGTIIPSPSQNLFARPQGVSRGRTLEQIPWTTYFERELFLEPTTGDDGSSTVTYHAYLNSPVGKGPLFVMHHGAGSSGLSFAVLSAEIRKRLPSAGILSPDARGHGSTVVMNDTELNLKLNILTEDLFSVIQLTKAQMSWPELPPIVLIGHSLGGAVVTDLAKSGRLGASLLGYGVLDVVEGSAMDALQSMLTYLSTRPTGFASLQSGIDWHIRSRTIRNSVSARTSVPALLVYDDSVDPTRPWRWRTDLSATQPFWEGWFVGLSKKFLEAKGGKLLLLAGTDRLDTELTIGQMQGKYALQVFPEAGHFIQEDLPEKTALAVVDFYRRNDRSALVLPPKVGDLLRQGKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEU0</accession>
    <name>E3QEU0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04540</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093416.1">
        <property type="nucleotide sequence ID" value="XM_008095225.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEU0"/>
    <dbReference type="GeneID" id="24409905"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04540"/>
    <dbReference type="HOGENOM" id="CLU_2037889_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="121" mass="12899" checksum="5FDE587D12E56C80" modified="2011-01-11" version="1">MGTAFTEPDGIQADKPAEQCFYRSPSREPAGPAGVLLDPPGAGRAALMHLNYDNNILDHYDRRGPPHPARTGQGGMPPARREMEGPAQAATRGADAGGGDDRERLRILALRIQSHVPLHGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEU6</accession>
    <name>E3QEU6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MGS207 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04546</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093422.1">
        <property type="nucleotide sequence ID" value="XM_008095231.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEU6"/>
    <dbReference type="STRING" id="645133.E3QEU6"/>
    <dbReference type="GeneID" id="24409911"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04546"/>
    <dbReference type="eggNOG" id="ENOG502QVA4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036627_0_0_1"/>
    <dbReference type="OrthoDB" id="10265971at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025337">
        <property type="entry name" value="Questin_oxidase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35870:SF6">
        <property type="entry name" value="MGS207 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35870">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G03330)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14027">
        <property type="entry name" value="Questin_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="409" mass="46962" checksum="6C82E4B8D51A5DA4" modified="2011-01-11" version="1">MAPGLLSYIPIVNRLVADSEQAHAIDIPAVKVHDVETDHDKRARCLKHLLRANHVNHSVIYHNLQYDNHAPHILSSAYLLGANDRQLQTIYEAEAKELEPWKESPAEVTEEDWRDLLGDKTYQRAYLDFFEDSLAYSSYDWKKVVDKFIFTGEEPLIHGLIGGLGHPLIHLGYAYEMNSKEIAIEALTLAATQYNFFHKYLDDKSYTRSSPFSSKSTFELVDKLAADSRLDGLFKEPALENLDALFDKHEGLVLEYWNAWTITDPVKQFEESQELAVALLVATVPRGTHGYNFFAVHLLTTSHAVRILLPFIPAKFHIDLVREWWLLVLAVYISLLRPKIDPDNVETDLKARHWGHVEHEALNSQWATDAHYVKAIRAMKEASRTWGDVHERYLASALTFVDNFRGWVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEW2</accession>
    <name>E3QEW2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">SURF4 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_04562</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SURF4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093438.1">
        <property type="nucleotide sequence ID" value="XM_008095247.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEW2"/>
    <dbReference type="STRING" id="645133.E3QEW2"/>
    <dbReference type="GeneID" id="24409927"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04562"/>
    <dbReference type="eggNOG" id="KOG3998">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056195_0_0_1"/>
    <dbReference type="OrthoDB" id="7859621at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005793">
        <property type="term" value="C:endoplasmic reticulum-Golgi intermediate compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045214">
        <property type="entry name" value="Surf1/Surf4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002995">
        <property type="entry name" value="Surf4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23427">
        <property type="entry name" value="SURFEIT LOCUS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23427:SF1">
        <property type="entry name" value="SURFEIT LOCUS PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02077">
        <property type="entry name" value="SURF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01339">
        <property type="entry name" value="SURF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="188"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ29418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="302" mass="33650" checksum="7D37D7697E4FC420" modified="2011-01-11" version="1">MAQQRGPSYGLGAGGPPSFGGPNADTSESSPLDMIREQTSKIEDFLDSVSEPIKPHLPVIGRFLIVVTFLEDAIRIITQWSDQLLYLHDYRHIPSGITHLFLIVNVLAMVACSSLVIIRKYSDYAVAGLMGVVVTQALGYGLIFDLNFFLRNLSVIGGLLMVLSDSWVRKSKAFAGLPQLDEKDRKMYFQLAGRVLLIFLFVGFIFSGTWSIWRIITSIIGFVACVMVVVGFKAKFSATLLVLILSIFNILVNNFWTLHEHHPHKDFAKYDFFQILSIVGGLLLLVNAGPGQFSIDEKKKVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFR0</accession>
    <name>E3QFR0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endonuclease/Exonuclease/phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_04889</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093765.1">
        <property type="nucleotide sequence ID" value="XM_008095574.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFR0"/>
    <dbReference type="STRING" id="645133.E3QFR0"/>
    <dbReference type="GeneID" id="24410254"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04889"/>
    <dbReference type="eggNOG" id="KOG0565">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002027_1_1_1"/>
    <dbReference type="OrthoDB" id="2248459at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004439">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.10.10:FF:000036">
        <property type="entry name" value="Inositol polyphosphate phosphatase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046985">
        <property type="entry name" value="IP5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000300">
        <property type="entry name" value="IPPc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200">
        <property type="entry name" value="INOSITOL 5-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200:SF240">
        <property type="entry name" value="INOSITOL POLYPHOSPHATE 5-PHOSPHATASE C9G1.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22669">
        <property type="entry name" value="Exo_endo_phos2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00128">
        <property type="entry name" value="IPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inositol polyphosphate-related phosphatase" evidence="2">
        <location>
            <begin position="788"/>
            <end position="1129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="143"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="407"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="423"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ29745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1184" mass="131209" checksum="A29BD5D710FD03E3" modified="2011-01-11" version="1">MAPPAQNGPDGSSIKPVSSLRAKFENMNKNGESAATAPGPSPPRTISPGPKPEFHPDAKASSESLPVPPRPRERANIPAPSLPPPLHEPVPRSPGRSLGIPPTLKPEPVKAPSVMVEPPQSPPKNTVSRFAHAEAPAFLNADPGSSTPTTPTTSRNFKMQSRPHTPSLEPRRSPRLSASQPPSPPPPRRSGEIRRENRPAVPPPINRAEKPSVRSQAKPHFYTEQQLAADGRGKLRQETSPFSSPPGSPDSLHEPTPPTLPTRPKAHFTQTEPPPPQRGRPLDVGFAPPPVHHSIVTKRNQREQETNGFVKGQITPQITGDRPSVPALPARPQTVAEPPPRPPVTMKPPPRPPRPGTNTPAAAHSVSELQPPPKRIVSTPATHPPPPTRLPGRANTVTDRTSERVAPRPPPPQPPQPEPTMSLIPSSSNSKVEINGSTPNFPDPANVNRRPPYIKQGMHEIQTKYDPRTFDVCGDLICTTGHLTRVWSLRDGELLMSFAHGEGIKATTVAFKPGTNVDEEGKRLWIGNNFGELMEADIATQSVIANKPGAHGRHEVVKIYRHFNELWTLDETGGLLVWGPDETSTPNLTNNPHQAFRLPKGHSFSMVVGDELWHATGKEIRVFAPTLDGQSQFQVLVRALMQDTAGEITSGTQVRSQPSKVFFGHADGKVSIYSTHDFSCLGLVNLSSWKINTLAGVGDHLWAGFNTGRVGVYDMQSTPWAVKKDWQAHDKNPVVKLVSDVSSCYRLDRHQVVSLGADNMVRVWDGLLQDDWHETEMKAMDTQYCEFQDLKVLCMTWNAGASTPHSLRYAQEDAEFIKSLLTANSSPDILVFGFQELVDLEDKTATAKRFLKVKKKEGSDQERMSHQYRDWRDFLLKSLDDYMPPDCLYHLLHTATLVGLFTCIFVKSTLRDRIQNLSAAEVKRGMGGLHGNKGAIVVRFMVDDSSLCFINCHLAAGQSQANSRHNDVAAILEAQILPPERDLNARIDSFVGGGDGTMILDHELCLLNGDLNYRIDTMSRDTVVIAVKQNNLAKLLERDQLLVAKRRNPAFKLRAFEEMPITFAPTYKYDVGTDNYDTSEKKRAPAWCDRLVYRGGGRIKQIDYKRHEVRVSDHRPVTGRFKFTVKKIQPKARAMAWMDCQQRFEDLKRHEINDDKMLYLTSVIGYDEATARVILQPSNDRRDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QG63</accession>
    <name>E3QG63_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Checkpoint protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_05042</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the HUS1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093918.1">
        <property type="nucleotide sequence ID" value="XM_008095727.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QG63"/>
    <dbReference type="STRING" id="645133.E3QG63"/>
    <dbReference type="GeneID" id="24410407"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05042"/>
    <dbReference type="eggNOG" id="KOG3999">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035754_0_0_1"/>
    <dbReference type="OrthoDB" id="419537at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030896">
        <property type="term" value="C:checkpoint clamp complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140445">
        <property type="term" value="C:chromosome, telomeric repeat region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044778">
        <property type="term" value="P:meiotic DNA integrity checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031573">
        <property type="term" value="P:mitotic intra-S DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.70.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016580">
        <property type="entry name" value="HUS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007150">
        <property type="entry name" value="HUS1/Mec3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12900:SF0">
        <property type="entry name" value="CHECKPOINT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12900">
        <property type="entry name" value="MITOTIC AND DNA DAMAGE CHECKPOINT PROTEIN HUS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04005">
        <property type="entry name" value="Hus1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF011312">
        <property type="entry name" value="Cell_cycle_HUS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR011312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ29898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="354" mass="39230" checksum="BDD01A4071F98254" modified="2011-01-11" version="1">MRFKTELKNIRTFSKLTAALNSLEKIAWVRLDDETARFTVIPDTGSQVWSSLPMDFIFDSYHIQSAEEHNTINLELPLQPLQRALRSALNSTSASLRLTKKDGIPVLSMTITTTTNASAGSGLPGRGNAAYVGLENDPFDDDDQGFTAEHLETSLRREREKIITQDIPVRVLHPETVETIMQPTVRETDVHITMPPLLQLKAISDRFTKLALSSGTNSRMSPKLELSANMFGNLKLRIATEAVDVSSTWSGLVNPELDPTQLEMPVEEHPSVKFKEAGPDKWATVRVDGKDWSRVLSVGRLEGRVVAAFADDHALILYVYVPQYDDASADDAVLTVGLQPTPILENMLTTNSIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGY5</accession>
    <name>E3QGY5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TAM domain methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_05267</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ30123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094143.1">
        <property type="nucleotide sequence ID" value="XM_008095952.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGY5"/>
    <dbReference type="STRING" id="645133.E3QGY5"/>
    <dbReference type="GeneID" id="24410632"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05267"/>
    <dbReference type="eggNOG" id="ENOG502SMFK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010595_2_4_1"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ30123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="181" mass="20658" checksum="D4B52EF5E3521B82" modified="2011-01-11" version="1">MTGVNMCGSFSNWPDVIAQAYENLEPGGYLELHDNMFPQTCDDDTMTEDFVPLKWTKCIVEATDKIGRVMTAAASFKSMLENAGFVDVVEKKAKWPFNPWAKDEKHKELGYWAQESALKGIEAISMAAFTRVLNWSPEEARVFCAEVRNEHKKIGIHAYYEVYVVWGRKPEETEEKEASHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHS2</accession>
    <name>E3QHS2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_05554</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697349">
        <property type="protein sequence ID" value="EFQ30410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094430.1">
        <property type="nucleotide sequence ID" value="XM_008096239.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHS2"/>
    <dbReference type="GeneID" id="24410919"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05554"/>
    <dbReference type="HOGENOM" id="CLU_2249928_0_0_1"/>
    <dbReference type="OrthoDB" id="4500473at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ30410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="104" mass="11231" checksum="36F86F0022093AFF" modified="2011-01-11" version="1">MGTGTETGPLDLGHFVPDLRRLDFPINRGEIEPFLRSMPMFPTASISFRWGDTQASEYGGVLGGGAPVLAAAGEPVTAKADVSAIFRSSVFNYEAYERLDTYVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QI03</accession>
    <name>E3QI03_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05635</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697349">
        <property type="protein sequence ID" value="EFQ30491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094511.1">
        <property type="nucleotide sequence ID" value="XM_008096320.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QI03"/>
    <dbReference type="STRING" id="645133.E3QI03"/>
    <dbReference type="GeneID" id="24411000"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05635"/>
    <dbReference type="eggNOG" id="KOG2865">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_6_4_1"/>
    <dbReference type="OrthoDB" id="275457at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05271">
        <property type="entry name" value="NDUFA9_like_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000358">
        <property type="entry name" value="NADH-ubiquinone oxidoreductase 39 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051207">
        <property type="entry name" value="ComplexI_NDUFA9_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12126:SF11">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12126">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 39 KDA SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="1">
        <location>
            <begin position="52"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="375" mass="42913" checksum="D0B17D466F3DEEC4" modified="2011-01-11" version="1">MAFFPTAVRSTQKAAHNVLRRQPLHDIAITRTGKPILRTQGGRSSLGGHTATVFGATGQVGRYIVNRLARQGCTVVIPFREEMAKRHLKVAGDLGRVVFMEYDLRNTQSIEESVRHSDVVYNLVGRNYPTKNFSLEDVHVEGTERIAEAVAKYDVDRFIHMSSYNANLDSPSEFYRTKARGEQVARSIYPETTIVRPAPIFGFEDNLLLKLASVMNLFTANNMQERFRPVHSIDVGQALELMLYDDSTAGQTYELYGPKEYSMAEIAQFADREIFKKRRHINVPKSILKPVAGLLNKYLWWPTMSADEVEREFIDQEIDETAKTFKDLGIEPGDISKFTYHYLQGYRSANFYDLPPATEKEKKEERKYLHVLDDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIA7</accession>
    <name>E3QIA7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Gluconolactonase convert D-glucono-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_05866</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094742.1">
        <property type="nucleotide sequence ID" value="XM_008096551.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIA7"/>
    <dbReference type="STRING" id="645133.E3QIA7"/>
    <dbReference type="GeneID" id="24411231"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05866"/>
    <dbReference type="HOGENOM" id="CLU_2922498_0_0_1"/>
    <dbReference type="OrthoDB" id="423498at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ30722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="61" mass="6859" checksum="001CF997EDABC59F" modified="2011-01-11" version="1">MNFYPVPPTIKAELHVRVPDHLRSHLPRRPVADEDGNLFIVDVPYGRILKISPSKEVSVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QID9</accession>
    <name>E3QID9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Haloacid dehalogenase-like hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_05693</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094569.1">
        <property type="nucleotide sequence ID" value="XM_008096378.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QID9"/>
    <dbReference type="STRING" id="645133.E3QID9"/>
    <dbReference type="GeneID" id="24411058"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05693"/>
    <dbReference type="eggNOG" id="KOG2914">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_13_0_1"/>
    <dbReference type="OrthoDB" id="40579at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008253">
        <property type="term" value="F:5'-nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990738">
        <property type="term" value="F:pseudouridine 5'-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000131">
        <property type="entry name" value="HAD superfamily hydrolase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.240:FF:000001">
        <property type="entry name" value="Haloacid dehalogenase-like hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18901">
        <property type="entry name" value="2-DEOXYGLUCOSE-6-PHOSPHATE PHOSPHATASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18901:SF38">
        <property type="entry name" value="PSEUDOURIDINE-5'-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ30549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="310" mass="34678" checksum="5A16784914BEF81E" modified="2011-01-11" version="1">MAPRTDFPPVRACLFDMDGLLLDTEDLYTACINVILEQYGRPLLPWNIKAKLQGRPGPESTRIFREWAQLPIDQDEYQKKLSALQRELFPSTQPLPGVPELLQNLGRTRYWDLKPADTAADKNPHRVHIALATSSHEANFKLKSDHLTELFSVFPSHRRVLGDDKRIAAGRGKPNPDIFLLALKTINDSLADGEKPITPDECLVFEDSVPGVEAGRRAGMRVVWCPHQGLLKEYAGREKEVLAGRTGEAGQVDMHQVGDVDDGWAEYLPTLEHFPYDKFGMVIPPIDVDNEPFMKENVGDVLVDSTNGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJM4</accession>
    <name>E3QJM4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">C6 zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_06206</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ31062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095082.1">
        <property type="nucleotide sequence ID" value="XM_008096891.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJM4"/>
    <dbReference type="STRING" id="645133.E3QJM4"/>
    <dbReference type="GeneID" id="24411571"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06206"/>
    <dbReference type="eggNOG" id="ENOG502SJ6A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024934_0_2_1"/>
    <dbReference type="OrthoDB" id="10265322at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053157">
        <property type="entry name" value="Sterol_Uptake_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47784">
        <property type="entry name" value="STEROL UPTAKE CONTROL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47784:SF5">
        <property type="entry name" value="STEROL UPTAKE CONTROL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="2">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ31062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="360" mass="41072" checksum="94C1D270EBD868D7" modified="2011-01-11" version="1">MATGLETFVPVLLYLDPAKPMGGWDGYCDEQRPACKNCIKHGVACGFLASPSLDPMLSLSQHAGDLNFLDLELLHHYCNFTAHTLSENPLLREFWRINVVKLGLECDYVMRSILSLSALHIAHLNPERKDGLLEKSMAHHEMSSRTAVSLMQNVQDENKAPLFIFSVLTIYIVLANSRYLNEAPLASAEQSPDWIVLFCGTRYLVGEPNTNPLISPIISRTVAHFQFREAPCHHTHLGDLEANINASESDDGLLAIYNHAINELYKSYGVFYESSEPQDIIDVFIWIAMVADDFLPLLRESRQKALVIFLYFCMLLRQLRSQWWLDVWASNLYAKTYELLDEEHRSWIRDPTIQNPDICL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJN7</accession>
    <name>E3QJN7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Zinc carboxypeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">GLRG_06219</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Extracellular metalloprotease that contributes to pathogenicity.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the peptidase M14 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ31075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095095.1">
        <property type="nucleotide sequence ID" value="XM_008096904.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJN7"/>
    <dbReference type="STRING" id="645133.E3QJN7"/>
    <dbReference type="MEROPS" id="M14.014"/>
    <dbReference type="GeneID" id="24411584"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06219"/>
    <dbReference type="eggNOG" id="KOG2650">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019326_1_1_1"/>
    <dbReference type="OrthoDB" id="3626597at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03860">
        <property type="entry name" value="M14_CP_A-B_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000165">
        <property type="entry name" value="Glucan 1,4-alpha-glucosidase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057246">
        <property type="entry name" value="CARBOXYPEPT_ZN_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705">
        <property type="entry name" value="PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705:SF143">
        <property type="entry name" value="SLL0236 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00765">
        <property type="entry name" value="CRBOXYPTASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00132">
        <property type="entry name" value="CARBOXYPEPT_ZN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52035">
        <property type="entry name" value="PEPTIDASE_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="17" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="8 15" id="KW-0732">Signal</keyword>
    <keyword evidence="11" id="KW-0843">Virulence</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="13" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180520" evidence="15">
        <location>
            <begin position="18"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M14" evidence="16">
        <location>
            <begin position="113"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="14">
        <location>
            <position position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS52035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EFQ31075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="415" mass="44703" checksum="FBDA5F60CB0A50BF" modified="2011-01-11" version="1">MRASIVSAIALVPLALGATVPRSTKVDYNGFKGLRITLPEGNADVADKIDELAATVLNPGSKDKLDVVVSPENLDAISQLANTTILVEDIGAAFAEEEVSTVYAVPSESWFTAYHSYADHLAFLKDLQSSFPGQSEIFTAGSSFQGRALTGIHIWGSGGKGSKPAVVLHGTIHAREWISTMTTEYLAYQLLAKYSSDSAIKSVVDKYDFYITPVANPDGFVYTQTTNRLWRKNRQTNTGSSCIGRDPNRNWPYKWELTGGASTSPCSETYKGASAGDAPEIKGLKAQIDSLSASQGGITLYLDIHSYGQYILWPFGYDCNYVAPDDAALRALAQRGATGIRGVSGTSYTIGNACRALYATTGDSTDYIHGVAKSKYTYTLELRDRGTYGFSLPASQIQPTVRETWAGVLAMLQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJZ3</accession>
    <name>E3QJZ3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ATP citrate synthase</fullName>
            <ecNumber evidence="2">2.3.3.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">ATP-citrate (pro-S-)-lyase 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Citrate cleavage enzyme subunit 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">GLRG_06325</name>
    </gene>
    <organism evidence="20">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes the formation of cytosolic acetyl-CoA, which is mainly used for the biosynthesis of fatty acids and sterols.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>oxaloacetate + acetyl-CoA + ADP + phosphate = citrate + ATP + CoA</text>
            <dbReference type="Rhea" id="RHEA:21160"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.3.3.8"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="15">Composed of two subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the succinate/malate CoA ligase alpha subunit family.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.8" evidence="2"/>
    <dbReference type="EMBL" id="GG697353">
        <property type="protein sequence ID" value="EFQ31181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095201.1">
        <property type="nucleotide sequence ID" value="XM_008097010.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJZ3"/>
    <dbReference type="STRING" id="645133.E3QJZ3"/>
    <dbReference type="GeneID" id="24411690"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06325"/>
    <dbReference type="eggNOG" id="KOG1254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006587_4_1_1"/>
    <dbReference type="OrthoDB" id="3261737at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003878">
        <property type="term" value="F:ATP citrate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006085">
        <property type="term" value="P:acetyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06100">
        <property type="entry name" value="CCL_ACL-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.261:FF:000003">
        <property type="entry name" value="ATP-citrate synthase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.230.10:FF:000005">
        <property type="entry name" value="ATP-citrate synthase subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000024">
        <property type="entry name" value="Probable ATP-citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="entry name" value="Citrate Synthase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="entry name" value="Cytochrome P450-Terp, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017440">
        <property type="entry name" value="Cit_synth/succinyl-CoA_lig_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033847">
        <property type="entry name" value="Citrt_syn/SCS-alpha_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017866">
        <property type="entry name" value="Succ-CoA_synthase_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="SUCC_ACL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23118">
        <property type="entry name" value="ATP-CITRATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23118:SF42">
        <property type="entry name" value="ATP-CITRATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02629">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01216">
        <property type="entry name" value="SUCCINYL_COA_LIG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00399">
        <property type="entry name" value="SUCCINYL_COA_LIG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01217">
        <property type="entry name" value="SUCCINYL_COA_LIG_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="19" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CoA-binding" evidence="18">
        <location>
            <begin position="41"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00054002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00060724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00062455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00076189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00083544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EFQ31181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="662" mass="72035" checksum="374B9D67174810E8" modified="2011-01-11" version="1">MPSATTPANGAKAASGLSANDNITRFSAPSRPLSPLPEHALFNDKTRCFVYGLQPRAVQGMLDFDFICKRKTPSVAGIIYTFGGQFVSKMYWGTSETLLPVYQEVSKAMAKHPDVDVVVNFASSRSVYSSTMELMECPQIKTIAIIAEGVPERRAREIAHKAQQKGITIIGPATVGGIKPGCFKIGNTGGMMDNIVASKLYRKGSVGYVSKSGGMSNELNNIIANNTDGVYEGVAIGGDRYPGTTFIDHLLRYQADPDCKILVLLGEVGGVEEYKVIKAVEDGVITKPIVAWAIGTCASMFKTEVQFGHAGAFANSTLETAKTKNEKMKEAGFYVPETFEDMPQVLKALYDSLVKNGTIKPQPEPVVPKIPIDYSWAQELGLIRKPAAFISTISDDRGQELLYAGMPISDVFKEEIGIGGVMSLLWFRRRLPPYASKFLEMVLMLTADHGPAVSGAMNTIITTRAGKDLISSLVAGLLTIGSRFGGALDGAAEEFTKAFDKGLSPREFVDNMRKANKLIPGIGHRVKSRNNPDLRVELVKEYVKAKFPSHKLLDYALAVETVTTSKKDNLILNVDGCIAVCFVDLMRNCGAFSSEEAEDYLKMGVLNGLFVLGRSIGLIAHYLDQKRLRTGLYRHPWDDITYILPQLGSGPPGAEGRVEVQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QK55</accession>
    <name>E3QK55_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP transcription factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_06387</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697354">
        <property type="protein sequence ID" value="EFQ31243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095263.1">
        <property type="nucleotide sequence ID" value="XM_008097072.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QK55"/>
    <dbReference type="GeneID" id="24411752"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06387"/>
    <dbReference type="eggNOG" id="ENOG502SKDE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028818_3_0_1"/>
    <dbReference type="OrthoDB" id="5086080at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021833">
        <property type="entry name" value="DUF3425"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012">
        <property type="entry name" value="B-ZIP TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012:SF7">
        <property type="entry name" value="B-ZIP TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11905">
        <property type="entry name" value="DUF3425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="522" mass="58416" checksum="A3D002792ECCDB52" modified="2011-01-11" version="1">MASDDGPNDTPTPPSGGPPAKVPSEKELARKIRKRELDRRAQRQARERTRNRIAELESQVKELRKDDSTRLSACMEQLATITHERDSLVDTVKSIEQIIRGHVLPSRQAPTATPLSPPGQSGPLPNPRDAIMTRPSSRSYSAPISFLPGTPSSTDPHALRSSGFGNGLGVVGTVPNDFSAPGCRASASTSDSQDFIEELEEEDEDEDHDDDAGIIVPPPTSPCDCAVAPTRSGPAPPKFNVWRAINRALTMRCHVSKAAQVAEDAEDEHVPVCALIEGWDVVAKSRPLSKLWRKLRAVDEVLFFNCSLTDRLAILRIMYMQLKYQFDPTPERPSQTLPHSQAIDFFVWPGLRERFVFGQHAYCNNQFWQLFASSIHVLWPFEFRDAYKKCVVTGQYQLSPMFEQRIRDLNVWTMGNDLFARFPELIADIPVTQSIGQSLTPVATPIMLQQAYLSQLKEREEQLMLEHASEQGSSQDVIDCTQAMQVFPPDLYRMAPSVFMAEYTPQSFDTNGVSHDSTPEYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKC9</accession>
    <name>E3QKC9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Down-regulated in metastasis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_06461</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697354">
        <property type="protein sequence ID" value="EFQ31317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095337.1">
        <property type="nucleotide sequence ID" value="XM_008097146.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QKC9"/>
    <dbReference type="GeneID" id="24411826"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06461"/>
    <dbReference type="eggNOG" id="KOG1823">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000327_0_0_1"/>
    <dbReference type="OrthoDB" id="360653at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052575">
        <property type="entry name" value="SSU_processome_comp_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046523">
        <property type="entry name" value="UTP20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011430">
        <property type="entry name" value="UTP20_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17695">
        <property type="entry name" value="SMALL SUBUNIT PROCESSOME COMPONENT 20 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17695:SF11">
        <property type="entry name" value="SMALL SUBUNIT PROCESSOME COMPONENT 20 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20416">
        <property type="entry name" value="UTP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07539">
        <property type="entry name" value="UTP20_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="U3 small nucleolar RNA-associated protein 20 N-terminal" evidence="2">
        <location>
            <begin position="903"/>
            <end position="1508"/>
        </location>
    </feature>
    <feature type="domain" description="U3 small nucleolar RNA-associated protein 20" evidence="3">
        <location>
            <begin position="1717"/>
            <end position="1935"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="637"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2578"/>
            <end position="2631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2588"/>
            <end position="2600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="2601"/>
            <end position="2624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ31317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="2631" mass="297320" checksum="4B9176DE01B8AC0A" modified="2011-01-11" version="1">MPSTSSGRITKSHKGKYSTPHQKNHRWESFAAKISKLNALDPLRKVRRHDLDAEDLEATTSYFRNGLQRWGELNISKGFNDFKRQALPLSESLAQILHFEEKIFGLLEESLAKQDKEALEPLLELLTAFAHDIGTRFEKYYAKSLHLIVAIAGKPQDVDVIEWTFAALAFLFKYLSRLIVPDLRPTYDVVAPLLGKARHPPHIARFAAEAMSFLIKKAAAPANRETALVTIVSHARDDLRTMVGERQFQLYQDGLMTMFAEAMKGPGQTIHSTGPAVFTALMQAIPETEADLTPTMTWTDLVCGVLTSVTHHSNDKDLAPVLEAMQGQVQGALSGPKPNKTWKFVPQVRVIGTAAGVRHGNRISNWTTLVENLTAMLDSMAQHSPEATEDKLGLVWRHVIVNAAIVWHQAPIEALIPSIKDFMTALQRERLMRWYIPFCAYFSNLDSTRFRSLFQTYFQRFIVSHWSDGRNEDMLCVFLPRMVQNGSLPSPGGKETCNLPRSWQDQIVSKFERLEASPFPERGAYDKDPQTWRDRCLPKYSALLDLLFSTTVHPSASAKIAELLLRKLRLALKPSSTLASDEVHFSISQGFHAYLRMSRAAGPVDPALNPLLRAALPRFSRSVGFLEAYLTYTEATKSQPPLADHQSSDSSEGSEEDPVVQALIENLSAPSHQLRLASLKILQQFESTPDELQCHTLMLDIEHTAMDLSSLRNVAMHLRKLGQNYSQLKENSWLIKAIPSFMFGMLTIKLSPLWDDTITALKLVGESKKGEENITATAFNWLETPSPRWSGPGSQPTLQNRQAMTDFDCRHVQQLWDMAGHVEEVVNNATDLMLKTFDEQQQTVEAHADTARAQALKVLTAMPHFAEKRSRKLVPFFLAWAGDDEDLSDSQEDEDVPTKGEDWSLQDRKALIGVFALFINPKVLYQNERVYHALLHLMENGDVEVQKLALKAILAWKQEGVRPYQENLEYLLDEARFKNEVTVFLQGESAIRPEHREELMPVLLRLLYGRTISKKGVASGRHGLQATRLTVLRNLSVEDTGSFLDIAIGGLKDARVIDESGFRASLFDKEILPVRKQLGFMNMMLPLINELGAHVGPYTEKLIHPVMYCLIFACRRLRESAAESDEEAEEPNDVSQDSMLKVIRTTGLKCLITLFRNAQDFNWPAYSVPIVNEVVTPRVEKLPIETAQSVSGIMQLLSTWSQLPRAALFISINDQILPKVIECLSVVKGKENVKIFALSIVRNLVKLAQAPAGESEFNELIRAELLDANMELTLKTIVTTLETQTMGNELLEACIETIVELSPLVETSANVHETLKIATFLLNQPPRRVNPRAKGKILLILERFITILGSEEAEEQTANIAIFDTLSSLFSYFKDRDNRQALARVLTALAEKDNTLREVAEICSDLNSFAKNRIDEPDYDKRLVAFTRITNKETPFSVRQWLPLLHNLIYYIRSDEEYGILASNSADCLRKFIREAASCSDQAVEAGFESHLKTILLPSIYTGAREESPTVRREYLRVFGYLLAQMPTWEPVADMKGLLTGELAEETSELPFFFNILSPATSRQLEAIRMLDSVNDGSEIGSQNLSQFFIPLLEHFIFGRTEGSDDQGLGAQATITIGNLAQSLDWKHYRVILQRYISYVESKPDNQKQVIRLLAKFCDALIFAVGQAAAEPMQVDDSETTSPSGKRLVLTKPPQDKLSKDVNNLFLPSLIKHLHEKDESEVSYRVPVGVIIVKLLKLLPLEEMGQKLAGVLTDICHILRSKSWEAREMARDTLVQIASVLGPTYFSFILKELRGALKRGYQLHVMSYTLHSMLLKIIPEFQQGDLDYTLRSIVSIIIDDIFGVTGQEKDAEGYISEMKEVKASKSQDSMELIAKSASISQLVVLVHPLQSLLLEKVDLKLVRKIDTLLARITAGLLQNPASESRDTLIFCYEVIQEVYKNQKTEVQPKIDYRLKKYLYQKGVKKDNHGTAGKYTFKLVKFAFDILRSVWKKYDSLRTATNIAGFVPILGDAIVGGEDDVKTAAFRLLTVLVKVPFNNDEDVQLYKVAVKEATKSISMSSSTTTELSQAALKLLSVVLRERKDIPVKDAAIDMLLGKLKDDLTETLYRHVTFNFLRSVLERKIETAVVYDTLDYVGTVMITNDDKDTRDLARGAFFQFLKDYPQRKARWVKQLNFVVANLTYEREGGRLSVMEVVHLLLMKSADDFVQEVISTCFLPLVMVLANDDSEKCCLAAGELIKEMFRRADKERTQNFMTLLRSWLEQEDNPAVTKLSLQAFGLFFEAKEPSSKHRKELELVLGKIGEIVGTGDIRVADEDLINTVLHDVQVLTEKYPARLLSSEAKELWGDVRGCLVHPENSVKLSTTKVLSTFLADFAGKSNKPGEALKGSHGLDLEVEDLEELVRLTLYALRTPEIDDALAAEITQILIFLGPRLPVKVQSVPEAETLGDRDETTAEEDRIDEHRKDLQYLFWKLSSILRRDVRPKSTAITPKTVAMEVLETICRRVPQDNLEPSFKTILYPLQNLTDPNIPVPFSTDDLFKTRLETLKTRAQILMDSLQKKFGTAEYTKQLLAIREEVRTRRQQRSSKRKIEAIAHPEKYGRDKRKKTEKKKERKKVRSHEHKQFRQAYKGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKJ6</accession>
    <name>E3QKJ6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Coiled-coil domain-containing protein 16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_06528</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697355">
        <property type="protein sequence ID" value="EFQ31384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095404.1">
        <property type="nucleotide sequence ID" value="XM_008097213.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKJ6"/>
    <dbReference type="STRING" id="645133.E3QKJ6"/>
    <dbReference type="GeneID" id="24411893"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06528"/>
    <dbReference type="eggNOG" id="ENOG502S9DW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041821_0_0_1"/>
    <dbReference type="OrthoDB" id="77607at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044773">
        <property type="term" value="P:mitotic DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033260">
        <property type="term" value="P:nuclear DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040050">
        <property type="entry name" value="ZNF830-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13278">
        <property type="entry name" value="ZINC FINGER PROTEIN 830"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13278:SF0">
        <property type="entry name" value="ZINC FINGER PROTEIN 830"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="70"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="242"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="300"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="87"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="257"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="335"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ31384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="357" mass="39016" checksum="433007389AC20729" modified="2011-01-11" version="1">MADVRSLLRQQRAARRIEHPHAAYSDAGKLLCTLCHEPIKTESLWDCHVRSSGHATKLKAVQKAFADTDGLAAADSAPSNKRKHDSDEDMEEEDTADSVRKKRSKTNMSRPARLSLGESDRDSKELTLTPPPLNRRTSTTPVQGVEIQIPSRPHTPAYKDGASSNSTPLVQPVGPSPLIPQEPTLGSAIAAAPPAQENGARSKAGSNGVQVDEDEWAAFEADIAAATAPYSEDAVIAAPAMTAEETAAAAKTEEEEQEKRRLAAEKDLMDEKEEATRALETEFEDMEELEARVRKLKEKREALRRQSDAGAAAPADKLISKAAEATGKENIEAVREEDEDEDEDEDEDDFMGFRYRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKN2</accession>
    <name>E3QKN2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyl hydrolase family 71</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_06564</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697355">
        <property type="protein sequence ID" value="EFQ31420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095440.1">
        <property type="nucleotide sequence ID" value="XM_008097249.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKN2"/>
    <dbReference type="STRING" id="645133.E3QKN2"/>
    <dbReference type="GeneID" id="24411929"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06564"/>
    <dbReference type="eggNOG" id="ENOG502RZ85">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019141_1_0_1"/>
    <dbReference type="OrthoDB" id="1046782at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051118">
        <property type="term" value="F:glucan endo-1,3-alpha-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11577">
        <property type="entry name" value="GH71"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005197">
        <property type="entry name" value="Glyco_hydro_71"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051130">
        <property type="entry name" value="Mito_struct-func_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173">
        <property type="entry name" value="ABC1 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173:SF33">
        <property type="entry name" value="ASCUS WALL ENDO-1,3-ALPHA-GLUCANASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03659">
        <property type="entry name" value="Glyco_hydro_71"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ31420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="418" mass="46374" checksum="516A09D53575E810" modified="2011-01-11" version="1">MVGNTEHYSASDWVEDIKLAQEAHIDAFALNMARGERMNAKAIADAFSNAEALGFKLFFSFDYAGRGPFSKDEVVSWIKKYAPISAYFRHQGKPFVSTFEGPDQAEDWHDIKAATGCFFVPDWSSLGAGPAVRAAGGVAGGLFSWAGWPWGAQDMETYVDASYVEALNGKPYMMPVSPWFYTNLPGYNKNWMWRGDHLWFNRWIQVNTLMPEFVEIISWNDYGESHHIGPIRDHALVAFDKDSGKAPYMYSLDHHGWRVLLPFAIDRNKNSKAVVTYEGVSFWYRPTPKRACDTGGTTGNTISQLQMEFQPYDIIDDSVFFTVLATESVKVTVSIGGAESQGILRDFPDGGVGLYHGSAPFNGRTGNVKIAVWRKDILLAEKSGPAINNDCHNGIEDFDAWAGGGLTSKASRPVNPIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKN6</accession>
    <name>E3QKN6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">SPFH domain/Band 7 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_06568</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the band 7/mec-2 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697355">
        <property type="protein sequence ID" value="EFQ31424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095444.1">
        <property type="nucleotide sequence ID" value="XM_008097253.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKN6"/>
    <dbReference type="STRING" id="645133.E3QKN6"/>
    <dbReference type="GeneID" id="24411933"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06568"/>
    <dbReference type="eggNOG" id="KOG2620">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024949_1_1_1"/>
    <dbReference type="OrthoDB" id="434619at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08829">
        <property type="entry name" value="SPFH_paraslipin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.479.30:FF:000004">
        <property type="entry name" value="Putative membrane protease family, stomatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050710">
        <property type="entry name" value="Band7/mec-2_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032435">
        <property type="entry name" value="STML2-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43327">
        <property type="entry name" value="STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43327:SF10">
        <property type="entry name" value="STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16200">
        <property type="entry name" value="Band_7_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="5">
        <location>
            <begin position="56"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="349"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="364"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ31424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="387" mass="41225" checksum="A1ABAF0AA59FAB91" modified="2011-01-11" version="1">MASAVTKAALFPPLRRALVQSRGFQTSTKSLLPSAFGVGSSIPPSYFQKASLPANTIIRFVPQQTAWIVERMGKFNRILEPGLAILVPFIDRISYVKSLKENALEIPSQSAITADNVTLELDGVLYTRVFDAYKASYGVEDAEYAISQLAQTTMRSEIGQLTLDHVLKERAALNTNITAAINEAAQAWGVTCLRYEIRDIHAPAGVVEAMHRQVTAERSKRAEILDSEGQRQSAINIAEGKKQSVILASEAMRSEQINRASGEAEAILMKAKATAAGIDAIAKSIANGEEAAQGAVSLSVAEKYVDAFAKLAKESTAVVVPGNVGDIGGMIATGLSVYGKVGEAQARTMAKQIAKGSEGEPTDDAPKGPKELKESVLESFDEAAGNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLJ4</accession>
    <name>E3QLJ4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidyl-tRNA hydrolase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_06707</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697357">
        <property type="protein sequence ID" value="EFQ31732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095752.1">
        <property type="nucleotide sequence ID" value="XM_008097561.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLJ4"/>
    <dbReference type="STRING" id="645133.E3QLJ4"/>
    <dbReference type="GeneID" id="24412072"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06707"/>
    <dbReference type="eggNOG" id="KOG3429">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089470_0_0_1"/>
    <dbReference type="OrthoDB" id="270639at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:peptidyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016150">
        <property type="term" value="F:translation release factor activity, codon nonspecific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070126">
        <property type="term" value="P:mitochondrial translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052104">
        <property type="entry name" value="Mito_Release_Factor_mL62"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11075:SF54">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11075">
        <property type="entry name" value="PEPTIDE CHAIN RELEASE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110916">
        <property type="entry name" value="Peptidyl-tRNA hydrolase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prokaryotic-type class I peptide chain release factors" evidence="2">
        <location>
            <begin position="64"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ31732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="192" mass="22246" checksum="0DFE50379DF6B642" modified="2011-01-11" version="1">MKLTTGFLKAVRPTLRNPLIRALQPIRWVRYQAFESDFDPEELDRARSWHKTFDGSQLPRGQTTYARSSGPGGQHVNKTESKAVTVWPVKDLLPVLPKLLHRSIRESKYYTARSDALTLQAQTHRHREANVEENHQKLIDEVKRIYQEAVPGETSPEKKKKHAEIAKSFNEGRLKQKKHLSSKKQSRRPSFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLK8</accession>
    <name>E3QLK8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_06721</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
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            <taxon>Fungi</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697357">
        <property type="protein sequence ID" value="EFQ31746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095766.1">
        <property type="nucleotide sequence ID" value="XM_008097575.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLK8"/>
    <dbReference type="GeneID" id="24412086"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06721"/>
    <dbReference type="eggNOG" id="ENOG502RIT4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_762936_0_0_1"/>
    <dbReference type="OrthoDB" id="4849338at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="64"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="116"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="268"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="116"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ31746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="305" mass="33300" checksum="2AD32865CBAC2373" modified="2011-01-11" version="1">MPAAHSFWWNGDNANMAMTHFLKNKYPLVQVTAWKRNPSTASDILKTWRKDAALLYTKVIKNGGDDDDVSGEEADEDVGENTEDGLNLPQSFAAEGGEGESSEGAADAIFTAHSRETKRRVEAPRRIESPKKARKHFIHESEGSEDDVFGFRRSNAKPTASTPKRAVAALITPTRSGGSSPIILVDSGTENEGPFEARGYYGRRRGRRCRFVRPESPPADIVVADPSPLTLTLVQTMASIEPAEAPAHEHECLAALQKAVDSVAKSCVAFSTKKRRETSCQLNELENKLGKLGSAVKRLNDAIQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLX4</accession>
    <name>E3QLX4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_07006</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095882.1">
        <property type="nucleotide sequence ID" value="XM_008097691.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLX4"/>
    <dbReference type="GeneID" id="24412371"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07006"/>
    <dbReference type="eggNOG" id="KOG0536">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1331860_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="114"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ31862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="206" mass="21796" checksum="4B888F3492E8CFD1" modified="2011-01-11" version="1">MGYVGVSLILASVVWVIVAPPPWIHPFMPPFLLTWRHLKPPPALPPSQKSGSPGEEATKQDGRTINPATKEEHQPRDAPPTLNPPQDPVAAQARAAMPPPAVSLSRPEPEPEEQTTPKAKPSAPAAPVPSFTLEAPSSHTPSTALSPSATAAAPGRGSMPPPPAPSSNINMMPPPPPPQLPPQSHHKHYILVTRFHCTRCRGGPTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMA1</accession>
    <name>E3QMA1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_07133</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096009.1">
        <property type="nucleotide sequence ID" value="XM_008097818.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMA1"/>
    <dbReference type="STRING" id="645133.E3QMA1"/>
    <dbReference type="GeneID" id="24412498"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07133"/>
    <dbReference type="eggNOG" id="ENOG502S522">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109915_3_1_1"/>
    <dbReference type="OrthoDB" id="2117453at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008253">
        <property type="entry name" value="Marvel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37451">
        <property type="entry name" value="MARVEL DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37451:SF1">
        <property type="entry name" value="MARVEL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01284">
        <property type="entry name" value="MARVEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="78"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="MARVEL" evidence="6">
        <location>
            <begin position="10"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ31989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="158" mass="17222" checksum="49CA99C1104D227F" modified="2011-01-11" version="1">MVALVPLAHIVAAVFSIIELGLSSYVASGYNGYNGWSGWWSRSPDIVNFIIFNSVWSLLVLAYVCLTPLYMTRLFHKLVSLALLVITTIFWFAGAIALAVFVGAPRCGANTFCGSSQAAVAFAFFIWAIFMFLTVLDTLEAMRSRGHSTKANHAYPGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMC3</accession>
    <name>E3QMC3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_07155</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096031.1">
        <property type="nucleotide sequence ID" value="XM_008097840.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMC3"/>
    <dbReference type="GeneID" id="24412520"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07155"/>
    <dbReference type="eggNOG" id="ENOG502TE4N">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_175700_0_0_1"/>
    <dbReference type="OrthoDB" id="4826387at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ32011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="77" mass="8497" checksum="E5FFD303FA0A95A8" modified="2011-01-11" version="1">MDIPQPVLKVVAAVLSVGILVELAILTRITRRSREEQADWDPGTGRSNTSGYEARDDGDEKAGPQRDKRMPPVDHTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMC5</accession>
    <name>E3QMC5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">SNF2 family domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_07157</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096033.1">
        <property type="nucleotide sequence ID" value="XM_008097842.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMC5"/>
    <dbReference type="STRING" id="645133.E3QMC5"/>
    <dbReference type="GeneID" id="24412522"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07157"/>
    <dbReference type="eggNOG" id="KOG0385">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000315_17_3_1"/>
    <dbReference type="OrthoDB" id="5857104at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000015">
        <property type="entry name" value="lymphoid-specific helicase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001315">
        <property type="entry name" value="SNF2 family helicase/ATPase PasG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10799">
        <property type="entry name" value="SNF2/RAD54 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="154"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="644"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="473"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="29"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="473"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="525"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="546"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ32013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="878" mass="98874" checksum="1E29A475AC873E31" modified="2011-01-11" version="1">MDSSATSEVESVMSTNRRRLDTSAPSSPPRDDSVEPIDAEFKHIMEEEAKARAANEKKTKAAKKAQNAKNRRRKKNELSKEERQKRARELEGLLARSAAFSDMLVTKTQALGRVGTSLEGETLGDHKLAMATQPKLMTGGEMRDYQLEGLTWMAEICIQGLSGILADEMGLGKTVQTISLIAHTREQNYLGPHLIVAPLSTLSNWMDEFEKWCPDIPVVLFHGDAQQRAKIKRERLDPNMKNGMPTKKFPVVCTSYEMVLRERASLAKFQWAFVIIDEGHRMKNFESKLFQELENFTSATRLLITGTPLQNNLRELWALLHFLMPGIFKDWEAFEEWFNFDDLQDEEGTEEFIADRENQELIKKIHVILQPLLLRRVKADVASHLPKKREYILFAPMTKEQTDIYNAINDRKVDTRAYLEDKVVERLTATLAAPVKKEVAAVKEIDIPIRSSPRKSNPKAAPEPKKPNAFAAMMSRARSSSSRAENAAKATSTTPSKTSSRASSKRKEAPASETPQAKSAKSSRHSTPSTTSRGRVTRGRRRYVDSDPDDEDKLSDDEFEAKLAREAEEDDSDDKTIVMSAEEQHRAKISEQAKKEMSAKKLGNPDMQLRLVCNSPHNFFDPWSYEGAPPVDESIVTSSGKMLMLDRLLPTLFAKGHKVLIFSQFKTQLDILQDYCELRKWNACRLDGSVSQESRRDQIKEFNENPDFKIFLLSTRAGGQGINLASADTVILFDSDWNPQQDLQAQDRCHRIGQTRPVIVYRLATKGTVEEELLLSADAKRRLEKLIIKKGSFKTMGQKVNLKEDLDKETLKSLLLKDGQIFNQSGDHEILSDKDLEVLCDRSDEAYAQAAQGTANADGYKVIETTSGGITIAGQDTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMV4</accession>
    <name>E3QMV4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">arginyltransferase</fullName>
            <ecNumber evidence="2">2.3.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_07336</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the R-transferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.8" evidence="2"/>
    <dbReference type="EMBL" id="GG697360">
        <property type="protein sequence ID" value="EFQ32192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096212.1">
        <property type="nucleotide sequence ID" value="XM_008098021.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMV4"/>
    <dbReference type="STRING" id="645133.E3QMV4"/>
    <dbReference type="GeneID" id="24412701"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07336"/>
    <dbReference type="eggNOG" id="KOG1193">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020349_0_1_1"/>
    <dbReference type="OrthoDB" id="74183at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004057">
        <property type="term" value="F:arginyl-tRNA--protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030700">
        <property type="entry name" value="N-end_Aminoacyl_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007472">
        <property type="entry name" value="N-end_Aminoacyl_Trfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007471">
        <property type="entry name" value="N-end_Aminoacyl_Trfase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21367">
        <property type="entry name" value="ARGININE-TRNA-PROTEIN TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21367:SF1">
        <property type="entry name" value="ARGINYL-TRNA--PROTEIN TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04377">
        <property type="entry name" value="ATE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04376">
        <property type="entry name" value="ATE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-end aminoacyl transferase N-terminal" evidence="6">
        <location>
            <begin position="13"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="N-end rule aminoacyl transferase C-terminal" evidence="7">
        <location>
            <begin position="139"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="301"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="326"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ32192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="425" mass="48986" checksum="D9EE9F203204B2BC" modified="2011-01-11" version="1">MDHRFSGFSYYAKATSLTPEYYQTLLDHYWRRSGTTLYRPDQLHACCVHYTLRLDSTQFKPTRDQRQTINRFNKFLTGEAYAKEAARVHPRTREQAKKRDSEFDLTERVHEAEYDSLQVPPEPAHVFTVTLEHDDFTEEKYLVYENYQRVVHKEHAADITRRGFQRFLCESPVQRRTITTDDGKEQRLGSFHQCYRLDGRLVAIGVLDLLPHCVSAVYFLYHESIHKYAPGKLGAIREIALAREGGYRYWYPGFYIHTCPKMRYKIDYTPQYILDPETLAWDLMDKRVTDLLDKKQYLSLSKEKPDTPGNGGPKEAIENTTAGDELAGEDPVSENGDDDKDTFLFNTGMPGIMSLDEIRSLDQMDHLKLRIDGSGMLFETGDLVAWQRQDVGSSGCLKAGIAELVAALGPELLDDLVVDFWNPHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QN53</accession>
    <name>E3QN53_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="13">TLC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_07435</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sphingosine N-acyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697361">
        <property type="protein sequence ID" value="EFQ32291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096311.1">
        <property type="nucleotide sequence ID" value="XM_008098120.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QN53"/>
    <dbReference type="STRING" id="645133.E3QN53"/>
    <dbReference type="GeneID" id="24412800"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07435"/>
    <dbReference type="eggNOG" id="KOG1607">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028277_4_0_1"/>
    <dbReference type="OrthoDB" id="3053196at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050291">
        <property type="term" value="F:sphingosine N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016439">
        <property type="entry name" value="Lag1/Lac1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560:SF11">
        <property type="entry name" value="CERAMIDE SYNTHASE LAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560">
        <property type="entry name" value="LONGEVITY ASSURANCE FACTOR 1 LAG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00724">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 9 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="95"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="216"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="262"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="319"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="12">
        <location>
            <begin position="130"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="385"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ32291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="417" mass="47745" checksum="567A7D7842C4A34C" modified="2011-01-11" version="1">MGANYMELQPGAQVPPRLLVNHHAKGFSKRKKANVLALMRRRIWTFPLILTIAMLSLYAINPTESNPTYHFIFPSYKLENDSGNTTQYGKGPWDIAFVCFYTVVLTFTREVCMQEMLGPLARVWGIKSRAKRARFAENMYTALYVTAIAPWGMHVMSRTPVWYFNTHGMYADFPHRTHDASFKCYYLLQAAFWAQQVVVMVLGLEQRRKDFQELVAHHVVTVALVALSYRFHFAYMGIAVYITHDISDFFLAVSKSLNYLENRLQGVSFGVCIAVWIYLRHYINLRILYSALPGSEFSTVGPYELNWETEQYKCPLSNVITFGLLAALQALNLFWLYCLLRSAYKFVFLGVAKDDRSEDEEESVIQPSVQGEEPATVGISAQEVEKHRKDFPSRVTGNGAVYMQGPLQGRKPRKTSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNE3</accession>
    <name>E3QNE3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Mannan endo-1,6-alpha-mannosidase</fullName>
            <ecNumber evidence="4 10">3.2.1.101</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_07525</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Random hydrolysis of (1-&gt;6)-alpha-D-mannosidic linkages in unbranched (1-&gt;6)-mannans.</text>
            <dbReference type="EC" id="3.2.1.101"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycosyl hydrolase 76 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.101" evidence="4 10"/>
    <dbReference type="EMBL" id="GG697361">
        <property type="protein sequence ID" value="EFQ32381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096401.1">
        <property type="nucleotide sequence ID" value="XM_008098210.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNE3"/>
    <dbReference type="STRING" id="645133.E3QNE3"/>
    <dbReference type="GeneID" id="24412890"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07525"/>
    <dbReference type="eggNOG" id="ENOG502QSWP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025694_1_2_1"/>
    <dbReference type="OrthoDB" id="4187847at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008496">
        <property type="term" value="F:mannan endo-1,6-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009272">
        <property type="term" value="P:fungal-type cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.20:FF:000006">
        <property type="entry name" value="Mannan endo-1,6-alpha-mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005198">
        <property type="entry name" value="Glyco_hydro_76"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014480">
        <property type="entry name" value="Mannan-1_6-alpha_mannosidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12145">
        <property type="entry name" value="MANNAN ENDO-1,6-ALPHA-MANNOSIDASE DCW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12145:SF36">
        <property type="entry name" value="MANNAN ENDO-1,6-ALPHA-MANNOSIDASE DCW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03663">
        <property type="entry name" value="Glyco_hydro_76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016302">
        <property type="entry name" value="Man_a_manosd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 10 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0732">Signal</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179874" description="Mannan endo-1,6-alpha-mannosidase" evidence="13">
        <location>
            <begin position="23"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="433"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="401"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR016302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ32381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="457" mass="49583" checksum="A4C7C6C5FAAF509B" modified="2011-01-11" version="1">MRHSFIARVATAVLASSGFANAVYSIASDDDIRSAGKDLAYDLMKFYDGNLTGHTPGILPGPPPAGDYYWWEAGAMWGTMIDYWHLTGDSTYNDVVMQAMLHQVGPNRDYMPPNYTASLGNDDQGFWGMSAMTAAEDGFPNPPEDQAQWLALAQAVFNTMASPDRHDNTCGGGLRWQIPFSNNGYNYKNSIANGCFFNIGARLARYTKNQTYADWAEKTWDWMTSVGFMDADYNIYDGGHVEQNCTDINKAQFSYNNGVFLLGAAMMYNYTDGSDKWKTRLDGLLKATFSLFFPNNIAVEVACEEHNTCTTDMLSFKGYVARWVSIVTQVAPYTAPTVLPILRTSAEAAAKQCTGQANQRTCGFKWSSGVYDGTIGVGQQMDVLAAVSSLLISQAKPPLTNTTGGISKGDPNAGSHSDNLLGEETPITTADKAGAGILTFLVLASAAGTFGWMSFGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNL1</accession>
    <name>E3QNL1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycosyl hydrolase family 43</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_07768</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697362">
        <property type="protein sequence ID" value="EFQ32498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096518.1">
        <property type="nucleotide sequence ID" value="XM_008098327.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNL1"/>
    <dbReference type="SMR" id="E3QNL1"/>
    <dbReference type="STRING" id="645133.E3QNL1"/>
    <dbReference type="GeneID" id="24413133"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07768"/>
    <dbReference type="eggNOG" id="ENOG502QVC0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016508_1_1_1"/>
    <dbReference type="OrthoDB" id="2139957at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09001">
        <property type="entry name" value="GH43_FsAxh1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041542">
        <property type="entry name" value="GH43_C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051795">
        <property type="entry name" value="Glycosyl_Hydrlase_43"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42812">
        <property type="entry name" value="BETA-XYLOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42812:SF15">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17851">
        <property type="entry name" value="GH43_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179881" evidence="5">
        <location>
            <begin position="19"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-xylosidase C-terminal Concanavalin A-like" evidence="6">
        <location>
            <begin position="320"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ32498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="536" mass="59235" checksum="D98A4D6A3AE1F4FD" modified="2011-01-11" version="1">MKLQLSSVLLAVVATVVAQATFSNPVLWEDLADIEVIRVNDTYYYTASTMHYSPGAPVLKSYNLVDWEFVGNSVPELVFGDEYYLNGTSRAYVDGIWASSLQYRESNGLFYWYGCIQSGEMKTWVFTASDPAGPWTAQPPINECFYDVGILVDDDDTMYAAYGRYNITVAQLSPDGLKPVRKEVVWEDSVRYLEGARFYHINSSYYIWLTRPADGQYVLKADSPWGPYTEHTVLDRMASPIPHSGTPHQGGIVDTPNGDWWYMAFLDAYPSGRIPVLAPLTWDEEGWPHIVTDEAGGWGKTYPVPVETDKKVNAAGEYTDTFDGPALSPQWAFNHNPDNSAWELGAEGLTLHTATVTDDLYSARNTLAHRILGPKSSGTFRLNLGNMADGDVAGLSIFRDESAYIGFRKAGDSLVLVAVHDVIASESTGWQTTSNGTVVATATASDIDLSGVADGTADVYLRIVADLHPTFGVAANNPAQLLYSIDGENFTQLGPDYWCHNRWQYFLAFRFAVFNYATKALGGSVLVKEFTLQLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNY3</accession>
    <name>E3QNY3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_07585</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697363">
        <property type="protein sequence ID" value="EFQ32571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096591.1">
        <property type="nucleotide sequence ID" value="XM_008098400.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNY3"/>
    <dbReference type="GeneID" id="24412950"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07585"/>
    <dbReference type="HOGENOM" id="CLU_2542444_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ32571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="83" mass="9322" checksum="9B9800FF400A5B0D" modified="2011-01-11" version="1">MVIAQDWPSKETKAEKIWRWSCRASKGELRKRRATAAHHVPGRTLDRDRSLLSTRRISSSAHSSAAFSAFSSMPLPRLGTEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNZ8</accession>
    <name>E3QNZ8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">adenine phosphoribosyltransferase</fullName>
            <ecNumber evidence="5">2.4.2.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_07600</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>AMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + adenine</text>
            <dbReference type="Rhea" id="RHEA:16609"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.4.2.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.7" evidence="5"/>
    <dbReference type="EMBL" id="GG697363">
        <property type="protein sequence ID" value="EFQ32586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096606.1">
        <property type="nucleotide sequence ID" value="XM_008098415.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNZ8"/>
    <dbReference type="STRING" id="645133.E3QNZ8"/>
    <dbReference type="GeneID" id="24412965"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07600"/>
    <dbReference type="eggNOG" id="KOG1712">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019466_0_0_1"/>
    <dbReference type="OrthoDB" id="363185at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002055">
        <property type="term" value="F:adenine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003999">
        <property type="term" value="F:adenine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006168">
        <property type="term" value="P:adenine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044209">
        <property type="term" value="P:AMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050054">
        <property type="entry name" value="UPRTase/APRTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32315">
        <property type="entry name" value="ADENINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32315:SF3">
        <property type="entry name" value="ADENINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="11">
        <location>
            <begin position="104"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ32586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="254" mass="28004" checksum="B14906E994C53628" modified="2011-01-11" version="1">MLEVQVRATKETRRARRRCHGGDDDDRDNKSDENNANDGTESLVLDHRPNFVFENGTAGDEAAQKFAEKHLLPFSHEDLHQLASMVRTIPDFPRQGIEFRHVLSIAEQTGGLALCTSLLRSQFTGDWSKVDVVACCEAGSFVFASALASQVNVPLALVREAGKLPAPTVSGEKRIEMNRYVVPRGGTVVVVDDVLATGKTLCAVLQLLVKAGIDVERVRFIAVAEFPIHRGRELLRRRGFGRVNVQSLLVFDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPG8</accession>
    <name>E3QPG8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribosomal RNA-processing protein 43</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_07900</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase PH family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697364">
        <property type="protein sequence ID" value="EFQ32756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096776.1">
        <property type="nucleotide sequence ID" value="XM_008098585.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPG8"/>
    <dbReference type="STRING" id="645133.E3QPG8"/>
    <dbReference type="GeneID" id="24413265"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07900"/>
    <dbReference type="eggNOG" id="KOG1613">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038194_5_0_1"/>
    <dbReference type="OrthoDB" id="45882at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035925">
        <property type="term" value="F:mRNA 3'-UTR AU-rich region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034473">
        <property type="term" value="P:U1 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034476">
        <property type="term" value="P:U5 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050590">
        <property type="entry name" value="Exosome_comp_Rrp42_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097:SF9">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097">
        <property type="entry name" value="EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="6" id="KW-0271">Exosome</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="11">
        <location>
            <begin position="45"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="23"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="164"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ32756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="339" mass="37126" checksum="3A0621965D9F5A17" modified="2011-01-11" version="1">MAASKGLPRDTFAKLSPHPFLLANLQPPAPANAARSNGRAPNEARIPNINTSSLTHANGSAVVRTGDTTVICGVRAETILASDIPNFRTAANTDEAKSSSELKDYDLLVPNIELATGCAPQFLPGVPPTTLAQTMSTRVYSLLHSSRLVDPEDLRIWYTRPAEDAEAEDDDDKMDDGEEKTEGERVIMAYWVLYIDIFFVSFDGNPFDVAWAAILAALRDTTIPIARWDPDREMIICSRDDPKPLTLHGFPVACTAGVFTGKETADRPAGGKFWTLVDPDRLEESLCEEEVTAVVDRSEGETKVLSISKHGGTVLQPPLIREFVGVAEQRWEQFRNAMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPR3</accession>
    <name>E3QPR3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Subtilase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">GLRG_07984</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 9 10">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697365">
        <property type="protein sequence ID" value="EFQ32840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096860.1">
        <property type="nucleotide sequence ID" value="XM_008098669.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPR3"/>
    <dbReference type="STRING" id="645133.E3QPR3"/>
    <dbReference type="GeneID" id="24413349"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07984"/>
    <dbReference type="eggNOG" id="KOG4266">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003559_3_1_1"/>
    <dbReference type="OrthoDB" id="10256524at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02124">
        <property type="entry name" value="PA_PoS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07489">
        <property type="entry name" value="Peptidases_S8_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010435">
        <property type="entry name" value="C5a/SBT2-like_Fn3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034187">
        <property type="entry name" value="Peptidases_S8_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF66">
        <property type="entry name" value="SERIN ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06280">
        <property type="entry name" value="fn3_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0134">Cell wall</keyword>
    <keyword evidence="6 9 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 9 10" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="7 9 10" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5 11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180812" evidence="11">
        <location>
            <begin position="20"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="12">
        <location>
            <begin position="146"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="13">
        <location>
            <begin position="373"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="C5a peptidase/Subtilisin-like protease SBT2-like Fn3-like" evidence="14">
        <location>
            <begin position="606"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8 9">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8 9">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8 9">
        <location>
            <position position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR615500-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF06280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EFQ32840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="886" mass="92154" checksum="8528E156286E77B7" modified="2011-01-11" version="1">MVRSSLLLPLVAAASAVQAYVQSPKTVAGAFIVELEDGQDASEFLAKTKADAVTRMNLNFTLFKGASIQFNDLDTADAKAAQLAQLPSVKNMWPVRTYGIPDSEVVWTGTQGRDYVDVKKRQLGNDTFSTHVQTQVDKLHRNGVTGKGIKVAVIDTGIDYLHPALGGCFGPGCLVSYGTDLVGNNYDGFNEQVPDPDPMDCGGHGTHVAGIIAAQSNPFGFLGTAPGVTLGAYKVFGCEGQVGNDVLIAAYNRAFEEGSNIITASIGGPSGWTDEPWAATVSRIVDAGVPCTVSAGNSGDQGIFFASTAASGRHVTAIASFDNAVTPALLIENTFTVAGGAPSTFAYTPGEPSEWAGVELPLWAITTDSSSDAALGCDPYPAGTPDLSGKIVLVKRGVCTFVVKAQKAAAAGAKYIMVYNNVPGAGSVSVTAVPEILAIGMTTPDQGAAWLKSIAAGSEVVLKMTDPEKAEQILTQSVNTATGGYVSSYSSWGPNWDGQQKPQFGAVGGNVLSTYPRALGSYAVLSGTSMSCPQTAGIVALIAEVRKTLDPATIENLLSAHANPVNFNSGSGPEGLLAPVSQQGAGLVQAYDAAYSTILLSHSSLSFNDTDNFIPELNFTIKNTGSADVSFDLSNVGAATAYTFETAGDLTPALFPNNLTAEHATVAFSESKVSVPAGGEATILVTPTPPTLDAARLPVWSGYIAINGSDGSSMSLPYMGIGGSLHSHVTMDEALMTTSTSATAAEYAPVASNYTYVLPPPGTANKTDAVVPALAIDMVFGSALVRADLVPLTTYPPNITHKVFGTKTLGQPRSFPYTYTSRGVFAVNWDGQMDDGSYAPAGKYKFSVKSLRVFGDASKLEEYDVAETQPFRIIYGAANATAPARH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPW3</accession>
    <name>E3QPW3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase C1A papain C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_08034</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697365">
        <property type="protein sequence ID" value="EFQ32890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096910.1">
        <property type="nucleotide sequence ID" value="XM_008098719.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPW3"/>
    <dbReference type="GeneID" id="24413399"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08034"/>
    <dbReference type="eggNOG" id="ENOG502ST85">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_187826_0_0_1"/>
    <dbReference type="OrthoDB" id="3789175at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ32890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="91" mass="10005" checksum="4EB27EDC31C73698" modified="2011-01-11" version="1">MTEDRSLPSGGGHAVVLVDCKPNCLTFLNSWGKTWGNNGSFSVEDHTVLEVDGIPMRFYDVYWLQSDLAPAELRAYNAEVDAVTASVKRNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQ40</accession>
    <name>E3QQ40_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Kinetochore protein SPC25</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_08122</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the NDC80 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Chromosome</location>
            <location evidence="9">Centromere</location>
            <location evidence="9">Kinetochore</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the SPC25 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697366">
        <property type="protein sequence ID" value="EFQ32978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096998.1">
        <property type="nucleotide sequence ID" value="XM_008098807.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQ40"/>
    <dbReference type="STRING" id="645133.E3QQ40"/>
    <dbReference type="GeneID" id="24413487"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08122"/>
    <dbReference type="eggNOG" id="KOG4657">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065188_0_0_1"/>
    <dbReference type="OrthoDB" id="4056921at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031262">
        <property type="term" value="C:Ndc80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23784">
        <property type="entry name" value="RWD_Spc25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.457.50:FF:000001">
        <property type="entry name" value="Probable kinetochore protein spc25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.457.50">
        <property type="entry name" value="Chromosome segregation protein Spc25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045143">
        <property type="entry name" value="Spc25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013255">
        <property type="entry name" value="Spc25_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14281:SF0">
        <property type="entry name" value="KINETOCHORE PROTEIN SPC25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14281">
        <property type="entry name" value="KINETOCHORE PROTEIN SPC25-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08234">
        <property type="entry name" value="Spindle_Spc25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 9" id="KW-0132">Cell division</keyword>
    <keyword evidence="8 9" id="KW-0137">Centromere</keyword>
    <keyword evidence="2 9" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 9" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="4 9" id="KW-0498">Mitosis</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromosome segregation protein Spc25 C-terminal" evidence="11">
        <location>
            <begin position="182"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="58"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ32978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="258" mass="30414" checksum="78C8369113F5BE01" modified="2011-01-11" version="1">MSSAFRESSLSASLNRQSLMATPSVAETLPNANFGFEELRDRMAKFTSKFDTFIEQGRKRVLEERNEFRMNLAELQEDQRMKKKDIEILQLKTSTHQQTVAKEKAETREMQAAIAQLSEERDKHLATRDALKKQIEETQREIDARLAAQRAHAKQLEAQSRFNVPELEFWQQNLGLRIEGAGKDDRLKFVYTYVDDQDWEREAWFELNTSSRDYDIRHCRPKLERERVERVLDQLNETRELAVLLKGMRELFVEAMKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQ73</accession>
    <name>E3QQ73_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_08155</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697366">
        <property type="protein sequence ID" value="EFQ33011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097031.1">
        <property type="nucleotide sequence ID" value="XM_008098840.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQ73"/>
    <dbReference type="GeneID" id="24413520"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08155"/>
    <dbReference type="HOGENOM" id="CLU_2413136_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ33011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="92" mass="11181" checksum="EA124A95FE27E009" modified="2011-01-11" version="1">MHRRWIVMSRYFNIRVQGREGEVFKRYQRLNLPHRFVFRFYNGSQLFCVRNQFIKRMIYFSCACSSTAGSTKMSYFGIYVYLEVVPDIKTHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQM0</accession>
    <name>E3QQM0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">5-formyltetrahydrofolate cyclo-ligase</fullName>
            <ecNumber evidence="5">6.3.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_08302</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(6S)-5-formyl-5,6,7,8-tetrahydrofolate + ATP = (6R)-5,10-methenyltetrahydrofolate + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10488"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.3.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.3.2" evidence="5"/>
    <dbReference type="EMBL" id="GG697368">
        <property type="protein sequence ID" value="EFQ33158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097178.1">
        <property type="nucleotide sequence ID" value="XM_008098987.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQM0"/>
    <dbReference type="STRING" id="645133.E3QQM0"/>
    <dbReference type="GeneID" id="24413667"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08302"/>
    <dbReference type="eggNOG" id="KOG3093">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066245_2_1_1"/>
    <dbReference type="OrthoDB" id="2015992at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030272">
        <property type="term" value="F:5-formyltetrahydrofolate cyclo-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009396">
        <property type="term" value="P:folic acid-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10420">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002698">
        <property type="entry name" value="FTHF_cligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024185">
        <property type="entry name" value="FTHF_cligase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23407:SF1">
        <property type="entry name" value="5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23407">
        <property type="entry name" value="ATPASE INHIBITOR/5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01812">
        <property type="entry name" value="5-FTHF_cyc-lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006806">
        <property type="entry name" value="FTHF_cligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="8"/>
            <end position="12"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="167"/>
            <end position="175"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00036539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR006806-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ33158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="246" mass="27177" checksum="3EDBE038F470BE3E" modified="2011-01-11" version="1">MASLVAAKNQLRSVMRNRLAGIAHDSVKAQSQTVFETLKTFGPYVEAKRVSIFLSMPSGEIQTDNIVRHALSAGKDVYIPYLHESPFAPGETPPRVMDMVRLRDLHDYESLQPDKWGIPSIDPKTVTLRDRVLGEPGAESPNTSFLDLMLLPGVAFDIDDNTGSLRRLGHGKGFYDLFIRRYASKYDGELSASKHPVLLYGLALSEQFLSLPSDSPIPVAQHDQQLHGLILGDGEIKRPADSSHSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRQ8</accession>
    <name>E3QRQ8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Complex I-ESSS</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">NADH-ubiquinone oxidoreductase ESSS subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">GLRG_08825</name>
    </gene>
    <organism evidence="19">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subunit">
        <text evidence="16">Complex I is composed of 45 different subunits. Interacts with BCAP31.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the complex I NDUFB11 subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697371">
        <property type="protein sequence ID" value="EFQ33546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097566.1">
        <property type="nucleotide sequence ID" value="XM_008099375.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRQ8"/>
    <dbReference type="STRING" id="645133.E3QRQ8"/>
    <dbReference type="GeneID" id="24414190"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08825"/>
    <dbReference type="eggNOG" id="ENOG502S7S9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_138649_0_0_1"/>
    <dbReference type="OrthoDB" id="2147978at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019329">
        <property type="entry name" value="NADH_UbQ_OxRdtase_ESSS_su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40637">
        <property type="entry name" value="ESSS SUBUNIT OF NADH:UBIQUINONE OXIDOREDUCTASE (COMPLEX I) PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40637:SF1">
        <property type="entry name" value="ESSS SUBUNIT OF NADH:UBIQUINONE OXIDOREDUCTASE (COMPLEX I) PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10183">
        <property type="entry name" value="ESSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="13 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="7 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <keyword evidence="18" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="64"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00031387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00046528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EFQ33546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="110" mass="12038" checksum="1E221E742F06D4BA" modified="2011-01-11" version="1">MTAIRPTAAIRAARAIKITAPSARAFSVTTRRAGGGSDFDPPTGWLWGVKPGEKYEKEGWETPFYTLFCGGIIATGVVLAFKPDTSLDTWALEEARRRLEKEGILPDPEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRY2</accession>
    <name>E3QRY2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">S1/P1 Nuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_08549</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the nuclease type I family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697372">
        <property type="protein sequence ID" value="EFQ33620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097640.1">
        <property type="nucleotide sequence ID" value="XM_008099449.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRY2"/>
    <dbReference type="STRING" id="645133.E3QRY2"/>
    <dbReference type="GeneID" id="24413914"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08549"/>
    <dbReference type="eggNOG" id="ENOG502QRXU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044365_0_0_1"/>
    <dbReference type="OrthoDB" id="441446at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11010">
        <property type="entry name" value="S1-P1_nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.575.10">
        <property type="entry name" value="P1 Nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008947">
        <property type="entry name" value="PLipase_C/P1_nuclease_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003154">
        <property type="entry name" value="S1/P1nuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33146">
        <property type="entry name" value="ENDONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33146:SF26">
        <property type="entry name" value="ENDONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02265">
        <property type="entry name" value="S1-P1_nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48537">
        <property type="entry name" value="Phospholipase C/P1 nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180735" evidence="8">
        <location>
            <begin position="19"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ33620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="307" mass="33616" checksum="976EF0063BD1D71C" modified="2011-01-11" version="1">MRSSLALLAAAAVQPALSWGNVGHRTVGYLAEKYLTDEAAAVFGELLANDRNYDISDAATWADTLRGHMGWASKYHYVNPRDDPPRLCGMKYPQDCPSSGCVISAIQNYTSQILDTSLPHINRKNATMFVIHFLGDIHQPLHATGLLRGGNDIRPVCWRRQPRDGVCTGPMSLHSVWDTQMPHRIRGLPPHLSPSDEKKAAAAWAADLHVRQAAAGVDASPAQQCIDLDTGACAAAWAGESNALVCSHVLRPGLTFLKGNDLSEEYYDDNWEVVEEVIGRAGVRLGAWLNAIAERLVREEAPKFEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRY9</accession>
    <name>E3QRY9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">POT family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_08556</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697372">
        <property type="protein sequence ID" value="EFQ33627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097647.1">
        <property type="nucleotide sequence ID" value="XM_008099456.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRY9"/>
    <dbReference type="GeneID" id="24413921"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08556"/>
    <dbReference type="eggNOG" id="KOG1237">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004790_4_1_1"/>
    <dbReference type="OrthoDB" id="8904098at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071916">
        <property type="term" value="F:dipeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000085">
        <property type="entry name" value="MFS peptide transporter Ptr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000109">
        <property type="entry name" value="POT_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11654">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00854">
        <property type="entry name" value="PTR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="140"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="196"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="252"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="369"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="407"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="448"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="486"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="522"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="554"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="49"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ33627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="614" mass="67332" checksum="A522988E707F1D4B" modified="2011-01-11" version="1">MSNAGGLQDDVLAKAHVPAAAAQGTEKEIRGSFDVTAAAAPSAADDQYYDSKSDDEYPDKPTEEELNTLRRVSGPIHWGIYTIAFAELCERFSYYGSSVLYTNFVMRPLPEGSTTGATYGRDVPAGALGMGQRASQGISLVNQFWAYLVPLFGGWLADSKLGRYKVIHIAIAVSTIAHIILVISAAPSVLSQGKVAFAPFFIGLFTLCCGTGLFKANISPLLAEQNKDTRMRVEVQKGERVIVDPAVTNSRIFLWFYFAINCGAVSGQISMVFVEKYHSFWLAFLLPTILFIICPVVLFMNKKNYHLTPPTGSVLEKFFQMSGFAAKRSGGITKLNWENAKPSNVPVAERPGWLTYDDAWVDEVRRGLMACKVFLFLPVFFLAYNQMTNNLTSQAGSMILGGAPNDVIQNLNPLSIIIMIPILDHLIYPGFRKMGFNFTPIKRMTTGFFFAAASMVAAAVMQHYIYKMSPCNEYATLCEEPAPINVWAQCLPYVLIGLAEIFTNVTSYEYAFSKAPENMKSLVMSVNLFMSAVSAAIGQAFTPLSEDPLLVWNYGSVAIIALVGGIAFWFCFNHLDAEEDELNLLKKTKFLGSNQPTAASAQGDANATQVAEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSB2</accession>
    <name>E3QSB2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TRIP4/RQT4 C2HC5-type zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_08883</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697373">
        <property type="protein sequence ID" value="EFQ33739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097759.1">
        <property type="nucleotide sequence ID" value="XM_008099568.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSB2"/>
    <dbReference type="STRING" id="645133.E3QSB2"/>
    <dbReference type="GeneID" id="24414248"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08883"/>
    <dbReference type="eggNOG" id="KOG2845">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027500_1_0_1"/>
    <dbReference type="OrthoDB" id="338816at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0180022">
        <property type="term" value="C:RQC-trigger complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072344">
        <property type="term" value="P:rescue of stalled ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039128">
        <property type="entry name" value="TRIP4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009349">
        <property type="entry name" value="TRIP4/RQT4_C2HC5_Znf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12963:SF4">
        <property type="entry name" value="ACTIVATING SIGNAL COINTEGRATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12963">
        <property type="entry name" value="THYROID RECEPTOR INTERACTING PROTEIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06221">
        <property type="entry name" value="zf-C2HC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TRIP4/RQT4 C2HC5-type zinc finger" evidence="2">
        <location>
            <begin position="234"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="69"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ33739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="520" mass="56600" checksum="82A91C0C70FD427B" modified="2011-01-11" version="1">MSLAQLSRLLPLPEEELKQMLDYATTLSKTEAAEHFNDLLGDSPQAVDFISSFNSRRQDTKPTAPTPTPTSSSTSAPAPAPKTWRGQKKKKQSNLHTPAPRQIDAAPPPGASYSKKDQQEEFYGGKKPSQPAAESSGGASSNFKQSLKSATPAPPPQQQQRTAAGYLISDKVKPKSNPVSRWSTPKPTAKPTKVSIAGGTPMAGASTALNDLDAAIRSLELTTNPTMGDDPKARRCNCVATRHPLQTAAPNCQSCGKVICVKEGLGPCTFCGTPLLSSDDVQGMIRELKLERGRERMAADREAHKRAEVSKKPAPFSQNKMSEAEAKAREHRDKLLNFQAQNAKRTTVRDEAADFDVSGAMAGSGGNMWSTPEDRARELKRQQKILREMEWNARPEYEKRRQVVSIDVVGGKVVRKMAAVERPMTPEEEDVVVHEDYKENDYVSSRQQSGGGGAFSHNPLLGGLIKPVWDAKGKGAQLEGRKDRKAQWRRVQDDLVDNEAVILDGGARGHSTTADEPECG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSE1</accession>
    <name>E3QSE1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Fungal specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_08912</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697373">
        <property type="protein sequence ID" value="EFQ33768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097788.1">
        <property type="nucleotide sequence ID" value="XM_008099597.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSE1"/>
    <dbReference type="STRING" id="645133.E3QSE1"/>
    <dbReference type="GeneID" id="24414277"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08912"/>
    <dbReference type="eggNOG" id="ENOG502S0TA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009239_1_0_1"/>
    <dbReference type="OrthoDB" id="3037908at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051711">
        <property type="entry name" value="Stress_Response_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47540">
        <property type="entry name" value="THIAMINE REPRESSIBLE GENES REGULATORY PROTEIN THI5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47540:SF2">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="78"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="271"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="715"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="24"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="271"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="722"/>
            <end position="732"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ33768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="802" mass="88642" checksum="20A3E2A66BE9B87B" modified="2011-01-11" version="1">MADAPTASTDAGLRDDGGPGVPTPASNISHPSPSSLPLPSSERRKRSLPEGSPDDGRSSSAAAVASANRRRSHKVSRACDYCKAKKLKCSGTIPCDVCTRKRLSCIYDASYRRGRPPTPPPATGTPRHSITGATLAPLLSPIEAQRFVVATTREALHGISRLTSHRRPLPTKAPLQLLPPGAAFPGLAMGTAARPSHPESGVVHPDAGGNASFPPTSRASPEVEMAEIEGQYFDNTSSLSFLHRAWKRLSSQRSHGSGVPGHMPSGIEQHQKLTRAGDKPFESQTLDPTTLPDRATGLGMMRFYFDVCVVTYRCLHQGYVSEWFEALLANAQNNRPLHRDIGHAKAAIVMAILAIVTLRQSKVRGVGSEQSSDLRRSDAYFCEALNLTEMEVGLPKLESAQSRILQGLYLLQTTRMNQAWYVFGSILPIVSALGLHRKSGRNRGSGDRDYIVSQCRKRTFWVAYTIDKYLSVVFGRPRMYHDDDIDQDFPDCVNDEEMTTQGRSRDEPEMDCHVESLIFHAKLAQLIDGISREVYAIKHIPKHDRLMAAHEYGQALHRWRKSLPHHLGTVRPMSLIPSFRRQNTALKLAYCHAIMHANRPFLLGMGASQSKQGSALEDSVDECINAAKVALETVDGMASDGTLFHAFWWTPYVTFCALAVVYVWEIQRGRKDGENGLFELADRCQNHLTEATAAESPGRRYSVILEELRQEAKYHSNVPVGRDQRHATEQTDRGGGAQSVQMDDDNNNDNNNNSARHPAPPADMGEVFQQQGFESMTNLLSGWETTDWLDLDSSVHQFLQKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QT38</accession>
    <name>E3QT38_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cupin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_09170</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697375">
        <property type="protein sequence ID" value="EFQ34026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098046.1">
        <property type="nucleotide sequence ID" value="XM_008099855.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QT38"/>
    <dbReference type="GeneID" id="24414535"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09170"/>
    <dbReference type="eggNOG" id="ENOG502S2RN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090569_0_0_1"/>
    <dbReference type="OrthoDB" id="1161823at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02223">
        <property type="entry name" value="cupin_Bh2720-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052538">
        <property type="entry name" value="Flavonoid_dioxygenase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43346">
        <property type="entry name" value="LIGAND BINDING DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14370)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43346:SF1">
        <property type="entry name" value="QUERCETIN 2,3-DIOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin type-2" evidence="2">
        <location>
            <begin position="47"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ34026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="163" mass="18057" checksum="B90FCB129B5ACFD9" modified="2011-01-11" version="1">MCKFPIPSSDPPKKEMQYFPDMTTALPSESGEFRRVLWTGLYSQLVLMTVPVGGDIGEEVHTVDQILTFTSGKGLAQVGGKEQEVKAGDMVIVPAGTKHQFLNKGPTPLILYTVYSPAEHKPTTVHKTKEQGDKEEEEGIDEPPEWSQRSKEQNGKEGWVKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QT49</accession>
    <name>E3QT49_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Fungal specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_09181</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697376">
        <property type="protein sequence ID" value="EFQ34037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098057.1">
        <property type="nucleotide sequence ID" value="XM_008099866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QT49"/>
    <dbReference type="GeneID" id="24414546"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09181"/>
    <dbReference type="eggNOG" id="ENOG502RXKS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011915_1_0_1"/>
    <dbReference type="OrthoDB" id="5376052at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF28">
        <property type="entry name" value="C6 TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="7">
        <location>
            <begin position="368"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="124"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="770"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="124"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="777"/>
            <end position="800"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ34037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="834" mass="93392" checksum="EAB475F131ACE3EC" modified="2011-01-11" version="1">MQHNGHFVSSRSPPAPNTKSIQHRIQPQDHDQSQTYSQNDQDSDDGNQLQSADENDLEQDDQDATRLGKRKRPISVSRNGALCEYKERKKPGLRAGYGRELEQRLDKLEEILRSHAEILQAALTSGQHQGTAASIRNSNPSLPSDQGTPRETNALFRPSESIRTPQAETALFLQKPSSYPPNTQSMEFGMPPPTPSMHEFQGQMPMASMPAPTSHISAIAHPSSAAQEYYGTNQTQLHSPDVAMAQSQASTSSDQELPPYDLLYALVDLYFKHINTWCPILHRKTTLDSLFGPSTLEESDRILLHAIVATTLRYSTDSRLTDESRQHYHSISKQRVLLYGMENSSVKALQALVILALDLVGDSNGPPGWNIMALITRSVVQLGLAVESTSFSVSPSFTSIYTLRAMILPEPKDFIEEESRRRLFWMIYLLDRYATLATAFEFALDDKEIDRTLPCRDDIWVKNQKVETRWFRTHDNQEDMNPEYDINKPENLGAFSYYIEILAILSKIHKFLKQPVDISALSDVEQWQMRYKELDNMLTSWKFGLPGEYGNMAKLFQPGNKMLNCGWVMLHATYHTAVIRLHSSAAYPTTRSPIFTPSYSASQRCHGAVENIAALGEFVVNNGLLAKLGPPFAFTLWVASRLLLVHGSTVEHKLSPQIQFFVETLREMGHYWPVAARYCILLQRVLDEHRDSERQGDGVTPSSVKILADMRRTAFDLDFLISRQPRANGIPSHSRLPSVTPARTPAPNELEYLDVFDFFNVPRLPVGNENVAGSRPAMNNANGQNGASSGMEGSSGSGSSHAPAKQGNEFNITNFTVDATSDWLFKQDGATFLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTE8</accession>
    <name>E3QTE8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_09280</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697377">
        <property type="protein sequence ID" value="EFQ34136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098156.1">
        <property type="nucleotide sequence ID" value="XM_008099965.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTE8"/>
    <dbReference type="STRING" id="645133.E3QTE8"/>
    <dbReference type="GeneID" id="24414645"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09280"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_13_4_1"/>
    <dbReference type="OrthoDB" id="268400at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF164">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="260"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="290"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="371"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="405"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="450"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="477"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="515"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="547"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="111"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="33"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ34136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="584" mass="64147" checksum="DDCC1BCB9B4F44E9" modified="2011-01-11" version="1">MNYSPASQPSQSPPFHNAGPPANSRSHVTAWPRENEKIDHGHNTPSTKYNDDTRYLESMQSPFDAQAQAQEGALYRDGKLILQPAPTQDPRDPLNLPLSRKLLACFCLSCFGALAAAAELILGAMLPVFALEYAGIDPKLLKSLTASGGLPANTDPLKYLSMLPNAPPIIEIYLLASLPVLVIGLSNLLLVPMAISVGRRPVVLTTGVIAIMGCIWAGNSRSLPSHLLARCVQAVGAGTVESLIPFVLQDMIFVHQRNSWISGVFAAQGVIIIVLGVATPQIIIDLSWRYMYFITAAGAAFFLIGVFFFMPETRWERTRAEMNGVPRNESGYKHAPRTFRYNIAFFHGEVQWRKGWNAFIDTLRTFFYPHIFFITMLNSVMIACAFAAGYTVAPALLTAPWSWNFLLLGLSLVPVLVAAIAVALVTGKAADWVANRIAKKRGVRLPENQLVNIIFPTLCGIIGSVIFGLAGSNQKDYSYFTFLTGFGMMAFGFLGANTIGAVYVLECYPHLAGPALVNVASFRCLLAFILSFKISDWVVEMGYFHSMMIYTGLISAFALLIPVVYIYGPAWRRRWPADHFGDDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTX0</accession>
    <name>E3QTX0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09426</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697378">
        <property type="protein sequence ID" value="EFQ34282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098302.1">
        <property type="nucleotide sequence ID" value="XM_008100111.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTX0"/>
    <dbReference type="GeneID" id="24414791"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09426"/>
    <dbReference type="eggNOG" id="ENOG502SA5Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095023_2_0_1"/>
    <dbReference type="OrthoDB" id="2151417at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38849">
        <property type="entry name" value="SMALL SECRETED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38849:SF1">
        <property type="entry name" value="SMALL SECRETED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179959" description="Small secreted protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="166" mass="17254" checksum="1B067DB6F0E66751" modified="2011-01-11" version="1">MKFSLIAVGFATLAAAAPLAARQNNVFSTQTYDELSISGGVAGNAKQEALQKLSGLPTDLTKVSKADIKFLNSVNQIANDAETEAFNPAIKAATGNAADALQCGKIKNKVLKLTATVLKLQAQQAQGDNVASKLATEQKKLDNNIKLDTAEAGNACTALKFDATTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTY5</accession>
    <name>E3QTY5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TLC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09467</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697379">
        <property type="protein sequence ID" value="EFQ34323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098343.1">
        <property type="nucleotide sequence ID" value="XM_008100152.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTY5"/>
    <dbReference type="STRING" id="645133.E3QTY5"/>
    <dbReference type="GeneID" id="24414832"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09467"/>
    <dbReference type="eggNOG" id="ENOG502SPB5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084815_0_0_1"/>
    <dbReference type="OrthoDB" id="3011762at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="231" mass="25764" checksum="2FED952FA25278D0" modified="2011-01-11" version="1">MVAVDFAPVLTGLVAYQLLNRCLHEAAKRFNPDFYAKLELDRHRKLRPYFVFPLGILLTLFTTPTCLAAYGETPSAADTFGTDRSFTTNGKICLGSRAVLWVSEMPLLSYSSEYVTHHLLSLGSLALVLVGKSPRRPIYLIYAGLVTELFSDAVALMRFHGRNPANSPTFRRVMLANILSMVSLRIIPAIAHAATMPETRPFYAAWFAALSPWLSVSQSSSRLYHYKKSNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QU59</accession>
    <name>E3QU59_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_09541</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697379">
        <property type="protein sequence ID" value="EFQ34397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098417.1">
        <property type="nucleotide sequence ID" value="XM_008100226.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QU59"/>
    <dbReference type="GeneID" id="24414906"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09541"/>
    <dbReference type="eggNOG" id="KOG2504">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_1_0_1"/>
    <dbReference type="OrthoDB" id="5667at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17352">
        <property type="entry name" value="MFS_MCT_SLC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF224">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="109"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="228"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="271"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="307"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="336"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="361"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="394"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="427"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="68"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="25"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ34397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="460" mass="49228" checksum="7ABB65E874177D67" modified="2011-01-11" version="1">MSKGDYPSSLADSQGPVAKMDQDTTDYSSDRPSTAQQLDPEKGAGAALSTDATQPPPPGSDAPDGGLVAWLVVLGAWATSFCSFGWVNSVGAFQEYYQNDLLPNYSPSTISWIPSLQIFFMMGLGPLVGHIYDHYGPRWLLFGGTILHVFGLMMTSLATKYWQILLAQGICSAIGVAAILSPGLSVIHGWFNRNRGAAFGVLSTGSSLGGVIFPIMVTRVIKTLGFPWAMRICAFIILALLIIANLTIKAFHPPRPQKLSRGQLLAPLKEFEFACVIIGFFLFTYGIFVPINYIQVQALDAGMDPNLAQYLVSMLNAGSLFGRITSGILGDKIGRYNIFVLVGFLTPIWMLALWIPAKTDGAIIAFAVLFGFCSGAYVSLIAPLIAQISPIQEIGFRTGIAFLANAIAGLTTNPINGAILSGSGGWVGIKIFSGVFCLAGTAFILAARVRRTGWKLMAAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUN1</accession>
    <name>E3QUN1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HypE protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_09713</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the tpcK family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697381">
        <property type="protein sequence ID" value="EFQ34569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098589.1">
        <property type="nucleotide sequence ID" value="XM_008100398.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUN1"/>
    <dbReference type="STRING" id="645133.E3QUN1"/>
    <dbReference type="GeneID" id="24415078"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09713"/>
    <dbReference type="eggNOG" id="ENOG502S8V9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115019_2_2_1"/>
    <dbReference type="OrthoDB" id="2519291at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009799">
        <property type="entry name" value="EthD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07110">
        <property type="entry name" value="EthD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EthD" evidence="2">
        <location>
            <begin position="23"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ34569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="128" mass="14671" checksum="D1CA0C4F0AE3DCD1" modified="2011-01-11" version="1">MRLPCIANVTAVGVKMLLFARRRQDLTPTQFHDYYENTHMPLLKNLSGDVFPLSHTRSYVIRDEPDFLARVVLGEQSDFVFDSMAILTWKDEAHFNATFTVYGDDNVGKKIAEDEENFIEWGKAVLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUP9</accession>
    <name>E3QUP9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Calcium-transporting ATPase</fullName>
            <ecNumber evidence="17">7.2.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">GLRG_09731</name>
    </gene>
    <organism evidence="21">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Catalyzes the hydrolysis of ATP coupled with the transport of calcium.</text>
    </comment>
    <comment type="function">
        <text evidence="16">This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Transports the calcium to the vacuole and participates in the control of the cytosolic free calcium.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15 17">
            <text>Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18105"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="17">Membrane</location>
            <topology evidence="17">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="17">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.10" evidence="17"/>
    <dbReference type="EMBL" id="GG697381">
        <property type="protein sequence ID" value="EFQ34587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098607.1">
        <property type="nucleotide sequence ID" value="XM_008100416.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUP9"/>
    <dbReference type="STRING" id="645133.E3QUP9"/>
    <dbReference type="GeneID" id="24415096"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09731"/>
    <dbReference type="eggNOG" id="KOG0204">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002360_9_3_1"/>
    <dbReference type="OrthoDB" id="3352408at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005388">
        <property type="term" value="F:P-type calcium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000028">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000018">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006408">
        <property type="entry name" value="P-type_ATPase_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01517">
        <property type="entry name" value="ATPase-IIB_Ca"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093:SF369">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093">
        <property type="entry name" value="CATION TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08282">
        <property type="entry name" value="Hydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 17" id="KW-0106">Calcium</keyword>
    <keyword evidence="4 17" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="13 17" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 17" id="KW-0813">Transport</keyword>
    <keyword evidence="3" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="170"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="208"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="382"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="423"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="19">
        <location>
            <begin position="127"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="298"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1214"/>
            <end position="1234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00059328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU361146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EFQ34587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1234" mass="135439" checksum="2779FEEF3740B9E9" modified="2011-01-11" version="1">MADEISSAPRHPDTGQTEPNDPFGKQFAEKLESREDEFDLRDDSVVENNTFAFTPTQLHKLVTARSLSALRRFGGLYGLAAGLRTDLAAGLSVDETSLDGTISFQEAVAAGEAGRSAEIAPLPPSSHHHDHGFKLNLDLVQHEKQGFADRRRIYGENRLPKRKQKSFLRLAWIAFNDKLMFLLTISATISLALGIYETIDASDDEPNIQWVDGVTVVVAILVIVFASAATDWQKNARFAKLIERKEQRDVKVIRSGKTQNISVYDVQVGDMMHIETGDVVAVDGVLVQGSGIQVDESSLSGESELVHKSVPSDSDMRSQKVHRSSATDPFILSGTTVSGGVGAYLVTSVGRNSIYGRTLMSLREDVEETPLQQKLGKLAKQLITFGAIAGIIFFLILFIRFLVGLRTMQATPSEKAETFFKLLILAVTVVVITVPEGLALAVTLALAFATTRMLKDKNLVRLIRSCEIMGNATCICSDKTGTLTQNNMTVVTGRIGLSERFGDAPEKATVTDDIKKELASDDAVGQSTPKVLLESLSGEVRHLMKNSIALNSTSFESDDPKEPGFVGASTETALLRFGREFLSMGLLNEERANNEIVDMFPFDASRKWMAVMSKLPNGSFRLLVKGAAEVVYEQCTNILNEPKIGLSVQPATDAVHDDVRLTIREYAKQMLRPIAMAYKDIDPRDAFERADDPDSIKFEKHFCDLTFIGVFGIRDPLRPEVLDSVRQCQDAGVFVRMVTGDNFLTAKAIASECGIYSPGGLAMDGPTFRKLTPAQLDLVVPRLQVLARSSPEDKLLLVSHLKGMGETVAVTGDGTNDALALKAADVGFAMGIQGTEVAKEAASIILLDDNFASIVKALVWGRTVNTAVKKFLQFQFTINITAGTLTVVSELAGDSIFTVVQLLWINLIMDIFASLGLATDYPSPDFLKRRPEPRNAPIVNITMWKMILCQAIYQLAVMFTLHYAGDGLFRPATDADRAALQTMVFNTYVWMQFFNQHNCRRVDNRLNIWYQGVLRNPWFLGVQCTTVAGQMVIIWKGGQAFDTRPLSGPQWGWSMLFGVLVIPLGALIRQVPDTFVYAFFQAVKKAFVATLHLLSKPLPAKWRRKAEEEVEDMGAAESWVLQTGATLLTPINYQWGSSAPPPGSKLAGRISSIPAAQREALIRAARAGTGDNEIDVPAMIEAARYVKVELSYGIEVHPDTSKEDPILLTSIGVDGEKCPPSQDPEILRYLQRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVG0</accession>
    <name>E3QVG0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">3-oxo-5-alpha-steroid 4-dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_09992</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the steroid 5-alpha reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697384">
        <property type="protein sequence ID" value="EFQ34848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098868.1">
        <property type="nucleotide sequence ID" value="XM_008100677.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVG0"/>
    <dbReference type="STRING" id="645133.E3QVG0"/>
    <dbReference type="GeneID" id="24415357"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09992"/>
    <dbReference type="eggNOG" id="KOG1638">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065395_0_0_1"/>
    <dbReference type="OrthoDB" id="5788137at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003865">
        <property type="term" value="F:3-oxo-5-alpha-steroid 4-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008202">
        <property type="term" value="P:steroid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016636">
        <property type="entry name" value="3-oxo-5-alpha-steroid_4-DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001104">
        <property type="entry name" value="3-oxo-5_a-steroid_4-DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039357">
        <property type="entry name" value="SRD5A/TECR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10556">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10556:SF43">
        <property type="entry name" value="STEROID 5-ALPHA-REDUCTASE DET2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02544">
        <property type="entry name" value="Steroid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015596">
        <property type="entry name" value="5_alpha-SR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50244">
        <property type="entry name" value="S5A_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="3-oxo-5-alpha-steroid 4-dehydrogenase C-terminal" evidence="7">
        <location>
            <begin position="117"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ34848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="294" mass="34027" checksum="CB8522C7ECEAFAAD" modified="2011-01-11" version="1">MPLIEGWLPPTRENWETITTVWQLSWPVFGSLQYVVSWYGMGKTSVQSRLNVPGRVAWFLMEIPGVTTLLYIMNTLPGQAGIDDLPWQNKVLAGLFTIHYAYRAVLFPIIQPSMSPIHVVVALSAVSFQLMNATCLGSYLAAYGPTTQSQWDKALGFGGIAQFVAGIAIFYIGLAGNYLHDEELREIRRAERRRQEKVAREQRRQGAQAVSVDKHYRIPDAMLFRHMLFPHYFCEWVEWFGFWMATGWSVPARAFFLNEIFVMFPRTRTGRRWYIEQFGEEKIRKKWTIIPGVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVM2</accession>
    <name>E3QVM2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Poly [ADP-ribose] polymerase</fullName>
            <shortName evidence="15">PARP</shortName>
            <ecNumber evidence="15">2.4.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">GLRG_10054</name>
    </gene>
    <organism evidence="22">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>NAD(+) + (ADP-D-ribosyl)n-acceptor = nicotinamide + (ADP-D-ribosyl)n+1-acceptor + H(+).</text>
            <dbReference type="EC" id="2.4.2.30"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the ARTD/PARP family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.-" evidence="15"/>
    <dbReference type="EMBL" id="GG697385">
        <property type="protein sequence ID" value="EFQ34910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098930.1">
        <property type="nucleotide sequence ID" value="XM_008100739.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVM2"/>
    <dbReference type="STRING" id="645133.E3QVM2"/>
    <dbReference type="GeneID" id="24415419"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10054"/>
    <dbReference type="eggNOG" id="KOG1037">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004841_2_0_1"/>
    <dbReference type="OrthoDB" id="2017365at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003950">
        <property type="term" value="F:NAD+ poly-ADP-ribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990404">
        <property type="term" value="F:NAD+-protein mono-ADP-ribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070212">
        <property type="term" value="P:protein poly-ADP-ribosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17747">
        <property type="entry name" value="BRCT_PARP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01437">
        <property type="entry name" value="parp_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07997">
        <property type="entry name" value="WGR_PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.142.10:FF:000002">
        <property type="entry name" value="Poly [ADP-ribose] polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.140.10:FF:000001">
        <property type="entry name" value="Poly [ADP-ribose] polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.228.10:FF:000002">
        <property type="entry name" value="Poly [ADP-ribose] polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.142.10">
        <property type="entry name" value="Poly(ADP-ribose) polymerase, regulatory domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.140.10">
        <property type="entry name" value="WGR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050800">
        <property type="entry name" value="ARTD/PARP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012317">
        <property type="entry name" value="Poly(ADP-ribose)pol_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004102">
        <property type="entry name" value="Poly(ADP-ribose)pol_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036616">
        <property type="entry name" value="Poly(ADP-ribose)pol_reg_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036930">
        <property type="entry name" value="WGR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008893">
        <property type="entry name" value="WGR_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10459">
        <property type="entry name" value="DNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10459:SF60">
        <property type="entry name" value="POLY [ADP-RIBOSE] POLYMERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00644">
        <property type="entry name" value="PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02877">
        <property type="entry name" value="PARP_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05406">
        <property type="entry name" value="WGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00773">
        <property type="entry name" value="WGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56399">
        <property type="entry name" value="ADP-ribosylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47587">
        <property type="entry name" value="Domain of poly(ADP-ribose) polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142921">
        <property type="entry name" value="WGR domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51060">
        <property type="entry name" value="PARP_ALPHA_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51059">
        <property type="entry name" value="PARP_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51977">
        <property type="entry name" value="WGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0013">ADP-ribosylation</keyword>
    <keyword evidence="11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 15" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 15" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="BRCT" evidence="17">
        <location>
            <begin position="21"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="WGR" evidence="20">
        <location>
            <begin position="249"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="PARP alpha-helical" evidence="19">
        <location>
            <begin position="384"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="PARP catalytic" evidence="18">
        <location>
            <begin position="519"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="113"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="350"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="8"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="115"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="151"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="202"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="352"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="364"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00024347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00033987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU362114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EFQ34910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="752" mass="81995" checksum="723A681FDFB7E028" modified="2011-01-11" version="1">MPPRRSARAAASASAAADPAPVAQPLNGAVIAISGTFDKKRTELESWLSSLGAGIAKSITKKTTHLISTPEDFKALTTKVASAQKNDIPIVSLQWAEDCESQGSLLSQTGYEYGQQAAKQATPAPAATNGSNKTQKKGASSQANGSHQNDSQSQSQPAAAASKANSASKKRTKAQVQSDTESDAKPDVKKQKAATGPKGKKKNTDDADDKTDVKKQAAATPDAKGKAADSSQLASKGFSIPLDEGCRVQGTVYIAPDGVIYDASLNQTNTTNNNNKFYRLQLVQDGTTYKTWTRWGRVGEWGQCAVLGGGSLNDALSNFEKKFKDKSGLAWADRGDDPKPKKYAFIERSYEPDSDDADSDDDNDAGHADKIKNEESDEKPEPVQCTLAKPVEELMNLIFNQKYFRDAMTSMNYDANKLPLGKLSKATILRGFQALKNMAELFNDSTLADSKYSMSVPEATEHLSNLYYSLIPHAFGRNRPPVIQTGVMLQKEVDLLDSLSDMKIASDLMKVDRKVHDIHPADRQYQGLGMKEMSPLDPNSSEFALLSEYLQGSKGATHHFNYKVEDIFRIERQGELERFEKSEFSSIKSDRRLLWHGSRVTNFGGILSQGLRIAPPEAPVSGYMFGKGIYLADMSTKSAGYCASSSSGGQALLLLCEAELGDPMQKLTNASYHAGETARANDMWSTWGQGRTGPSRWKDAGSVNPSLEGVKMPDVSVKAGDNNISNAYLMYNEYIVYDLSQVRLRYLFRVKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVT3</accession>
    <name>E3QVT3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ribonucleotide reductase inhibitor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_10115</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DIF1/spd1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697386">
        <property type="protein sequence ID" value="EFQ34971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098991.1">
        <property type="nucleotide sequence ID" value="XM_008100800.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVT3"/>
    <dbReference type="GeneID" id="24415480"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10115"/>
    <dbReference type="eggNOG" id="ENOG502S8VH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050885_2_0_1"/>
    <dbReference type="OrthoDB" id="4072855at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990846">
        <property type="term" value="F:ribonucleoside-diphosphate reductase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008104">
        <property type="term" value="P:intracellular protein localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013900">
        <property type="entry name" value="RNR_inhibitor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28081:SF1">
        <property type="entry name" value="DAMAGE-REGULATED IMPORT FACILITATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28081">
        <property type="entry name" value="DAMAGE-REGULATED IMPORT FACILITATOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08591">
        <property type="entry name" value="RNR_inhib"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="79"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="123"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="36"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="92"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="150"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ34971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="247" mass="26470" checksum="7B019E034156A4A6" modified="2011-01-11" version="1">MSAPRTKRPFAGASSDPAQRQITSFFAPRSGPAPPSETSSTLTTNKLPPDVQSNLLSVGMRVRKSVPEGYKTGTYKSVKLSADTAEPRTPVVRTTNPASNRNTAAASQRELLPFCGINKVGGLASQPTYASESEHEAEGVPGLDDLPGLSSSQESVESTASDGRSKKRFFIDEETDEPVQVWANHTAWLDSEVSPRSLAPSGFANARPFAVPRKSHRKSMAGQENLVVDDFDDADFLVSPDTDMSDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWH0</accession>
    <name>E3QWH0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA wybutosine-synthesizing protein 2</fullName>
            <shortName evidence="2">tRNA-yW-synthesizing protein 2</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_10352</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to the C-7 position of 4-demethylwyosine (imG-14) to produce wybutosine-86.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>4-demethylwyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine = 4-demethyl-7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-methyl-5'-thioadenosine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36355"/>
            <dbReference type="Rhea" id="RHEA-COMP:10164"/>
            <dbReference type="Rhea" id="RHEA-COMP:10378"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64315"/>
            <dbReference type="ChEBI" id="CHEBI:73550"/>
            <dbReference type="EC" id="2.5.1.114"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">tRNA modification; wybutosine-tRNA(Phe) biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697389">
        <property type="protein sequence ID" value="EFQ35208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099228.1">
        <property type="nucleotide sequence ID" value="XM_008101037.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWH0"/>
    <dbReference type="STRING" id="645133.E3QWH0"/>
    <dbReference type="GeneID" id="24415717"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10352"/>
    <dbReference type="eggNOG" id="KOG1227">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023588_0_0_1"/>
    <dbReference type="OrthoDB" id="2387925at2759"/>
    <dbReference type="UniPathway" id="UPA00375"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102522">
        <property type="term" value="F:tRNA 4-demethylwyosine alpha-amino-alpha-carboxypropyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008175">
        <property type="term" value="F:tRNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031591">
        <property type="term" value="P:wybutosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030382">
        <property type="entry name" value="MeTrfase_TRM5/TYW2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026274">
        <property type="entry name" value="tRNA_wybutosine_synth_prot_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23245">
        <property type="entry name" value="TRNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23245:SF25">
        <property type="entry name" value="TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038972">
        <property type="entry name" value="Trm12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51684">
        <property type="entry name" value="SAM_MT_TRM5_TYW2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="SAM-dependent methyltransferase TRM5/TYW2-type" evidence="4">
        <location>
            <begin position="99"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00049400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR038972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ35208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="416" mass="46351" checksum="66D9FD8E108DE01D" modified="2011-01-11" version="1">MAAPNGKPRGKKPKPENPISAATRAWLLSLPPQAQPWRTSDELDTLLNQQTPKRFAIYEPMLLLPSGSFDKGLWRTLLGHPDITDDKIHQLWDAILRDVSNTGSSMLTHLAINEGIPLQTGAKTDDGIAVEKGENILRTPSGLKILHGDFGPPINPAKPSSEDFETAFWVSTKQNGIYQTWAPRWTMFSRGNIKEKTRLLEFHSHAVPEAMSHRRRTASSLKKHWAVDLYAGIGYFTFSYAKLGLRVLCWELNPWSVEALRRGAVANGWRVRVVQGADLELPAAQLLTGDEQIVVFLQDNQKAADRIADIRASGTPVDILHVNGGLLPTSEPTWRPAWDMTATSPEGCWLHLHENVGIHDIEPRRANIQSLYDGWAAATESGRAAMVEHVELVKTYAPDVWHCVFDVHITISNKVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QX49</accession>
    <name>E3QX49_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10581</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697393">
        <property type="protein sequence ID" value="EFQ35437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099457.1">
        <property type="nucleotide sequence ID" value="XM_008101266.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QX49"/>
    <dbReference type="STRING" id="645133.E3QX49"/>
    <dbReference type="GeneID" id="24415946"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10581"/>
    <dbReference type="eggNOG" id="ENOG502QSCZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016311_1_0_1"/>
    <dbReference type="OrthoDB" id="5430106at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031931">
        <property type="term" value="C:TORC1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22794">
        <property type="entry name" value="THAP DOMAIN PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22794:SF2">
        <property type="entry name" value="THAP DOMAIN-CONTAINING PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="536"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="157"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="209"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="396"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="569"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="584"/>
            <end position="597"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="623" mass="65899" checksum="8EB053073B9DA824" modified="2011-01-11" version="1">MVRDGRDADDSSATNQSRRPPLNRDESDSTNSDQTHRDHHHQHRSKQKHVVGTGRLHARVPSSKALHKHHGSTASKLNHRRHASPSPDRNRAAAAAAGGHRRVQSEAKLSRDSSSANISKTASATSLRRNKSHSEVNKPANIKSSEKLKRTGSNSAVSKVKSQKSQVHFDLGNDGQEDDWVDASTSASPYLSRRGSLASTQASAKPDDNSSANNSVNSVNDSANNSANNSANNSRADAPTAHPSSLAAATPDYDTVQHKEYLTSRLLQRIPSHGAPPKMTTDTATASRRGDSRSPDSIGRGSTLAESHNVSTLPSSGDELISRFVNAGSSGAAREGSFYQPPTPRPSSLGSEATPPRRPQSSSSGRPGRQERLQDLPLLDDEASEVRGETDGTALAPRSARRSAPPAEKSRTQQKLNLQRASSVIEPGQAAGGGVGAVGASPLVGIGGPGYDGGASRDPRVTKQLERTGMEYLSVRRFQNPVVRSLDRLVQVNRANKNQRIPRTGTANGNGKAASMRGGVVPGQQQHMRNSSLNESALAAASGGTGSARRPVTPRAYSIRTNGAGSSYEADHDDHQSSRALHEGTGVQGLSGSSLVGGEEDEGVTALLRNLWEKNPDLSASQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QY28</accession>
    <name>E3QY28_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">OPT family small oligopeptide transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_10921</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697399">
        <property type="protein sequence ID" value="EFQ35766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099786.1">
        <property type="nucleotide sequence ID" value="XM_008101595.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QY28"/>
    <dbReference type="GeneID" id="24416286"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10921"/>
    <dbReference type="eggNOG" id="KOG2262">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004965_1_1_1"/>
    <dbReference type="OrthoDB" id="9986677at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00727">
        <property type="entry name" value="ISP4_OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="115"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="258"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="300"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="407"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="460"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="486"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="568"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="636"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="687"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="715"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ35766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="779" mass="87052" checksum="DC2DD312CD5AC745" modified="2011-01-11" version="1">MADDSKHGTNVSQAPTDRGNFQKDHQWSPDLSQEKGDMTEKPRQNGDADEVVVGGFALDEDSPYEEVRAAVRNTDGEEVANTVRAWILGMVFVTIGSGLNMFLSMRSPAINFPSIVVQLLVYPIGCLWAKVMPTKVFNTFGVQWTFNPGPFTIKEHVVITLMSNVSIGYAYSTDALLALQGKPFYDINLGWGFQLLFTLSSQLIGIGLAGLCRRFLVWPSAMIWPNQFANTSLFYALHDKSKSEGTHSNGWIISRYRYFFYVLGAMFCYYWIPGVLWQGLSVFAFVTWIKPNNIVVNQLFGGFTGLSLIPITFDWTYVSAYLGDPLLSPTHTHINVLIGLFTFIIIPTIGIAYSGALFAEYLPINTSQTYDNTQGRYNVSKILGPGHTFDVNKYKEYSPLFLPPTFALNYGLSFAALTAAIVHCVFFHGKEIWYRLKAARNQEADIHLKLMRKYRDAPEWWYAALLVIAIGLGLATAEGYDSQLPWWAFFVANLLAMIFVLPTCTILAISNLGLALNVLSPFLAGFMIPGKPIGVMIFKVYSTITLGQAQTYTGDLKMAHYMKIPPRITFWCQVVATIWAVFVQIAVMNWTLGNIEDCCALSQHAHFTCPNGRAFFSSSIVWGVIGPQRMFGAGSIYQYFNIFWLIGACLPIVFYVLAKVLNLKFAKTLHAPVMLGAMGWLPPATPLSFSSWAIVGLIFNHGIRKRFRGWWQTYNYITAAALDAGLIISTIVIFFAITFPNVTIPQWWGNVDVYNTLDSTYGAILKTVGENQTFGPASW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYA3</accession>
    <name>E3QYA3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_10950</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697401">
        <property type="protein sequence ID" value="EFQ35841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099861.1">
        <property type="nucleotide sequence ID" value="XM_008101670.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYA3"/>
    <dbReference type="STRING" id="645133.E3QYA3"/>
    <dbReference type="GeneID" id="24416315"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10950"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_10_1"/>
    <dbReference type="OrthoDB" id="6692864at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11061">
        <property type="entry name" value="CYP67-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF187">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="496"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ35841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="552" mass="62061" checksum="895EBF6C98BD8C13" modified="2011-01-11" version="1">MNVLFGSGCQDAVVCGLGLLCGFAVHRGIFIHGEWHVQAPQILLGHLWLFASFAGLSRYYGGTAIGELSRSLLILSAGYLPGLFASITLYRVFFHQLSTAGFKGPWYARVTKLWHIWACRNCKNHLVLESLHEQYGDFVRTGPSEITVFHPGVFMAVDGPRSECIKAEWYDILHPDRALVTTRVKPIHAARRREWNYGFSAQALVQHETKILKWIQELDKCIEANAKAQVPSEVRDLFFWFGFDVMGDFVFSKSFDMLHQQQWHHIIVRLQRALSLLGPFSPAPWLIQVGFKLGPRVGVLKDWFDMVAWCERQMRVRLDAATPKPGAPDLAHYLMELNHGQTEQPDRLTWLFGDSLLAIVAGSEPTAAALIGVFCEIAKHPEHADKIYAELEDVDVTNLKVLTSLPHLNAVINEGLRLYPALLTGGARKTTENGATIGGTFIPPNTTIIAPRHVISRREDCFEKANDFIPERWTTKPEMIHNAAAFAPFGTGHHSCLGRFLATDTMRFVVARLVKKYHIRLAPGETGNRVFDEIKDQFTSNPGPLSLCFELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYE0</accession>
    <name>E3QYE0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11069</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697402">
        <property type="protein sequence ID" value="EFQ35878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099898.1">
        <property type="nucleotide sequence ID" value="XM_008101707.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYE0"/>
    <dbReference type="GeneID" id="24416434"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11069"/>
    <dbReference type="HOGENOM" id="CLU_752289_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="368" mass="39814" checksum="ABC41C6591DB8B0A" modified="2011-01-11" version="1">MRLEHGRKKAEMTASKSTSKSTPKSAEKITEADCAAAGEAATAWALFVKRQADKEVDNRPNRMANEDAHDDNTIEPAIEIEASTEEGGDFELETELTTSLEISAEIFKNLARDQSVDGDHQNTFLDKEASGNLFPFTRPHGNGIFTNPDGDEDRSKLHMLSSTASVVTPSGNAHQKRKRASLIADDPQGRKKTDVVSSPPVRSRNKNSISRLSDTADKFADPHGNASQQLSSVTQSQEGSVRNGGVAEHSMGSQGSSRITELLSRSQEYPPGTSEHNDSQKQSRGFAQHPMSIQALSSTTGRQGNVEGHSAVAGTSAIERRITIINWIEALLQVRHLTTGGGPNSVDAKHRSVSMGMIKGLIEEYELI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYE2</accession>
    <name>E3QYE2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11071</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697402">
        <property type="protein sequence ID" value="EFQ35880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099900.1">
        <property type="nucleotide sequence ID" value="XM_008101709.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYE2"/>
    <dbReference type="GeneID" id="24416436"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11071"/>
    <dbReference type="HOGENOM" id="CLU_1120099_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="248" mass="28052" checksum="D83C2BA8A770CD14" modified="2011-01-11" version="1">MDTTKDPIRSGRKKAPLMKTSNSLLDEINVAGHIELLSLTINDLKTTQDYAASIPDISAELESEIMTKRAKLISMSQKLRSLPIQRTQSIQRPDSLEFKRLERNIAFMIKEKELHLKNEDETEPFDPTKHDWEKTKTEMDQFATDLKQAIEENFIGTAIRFEDWENDDCDMNDFCDAFEAGMQAQEQKHSPSGSIEDQSECEAGSGDSGGTGEDKDPMEMINAGNDVHTHRFLVKYSALSVSILCRCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYT0</accession>
    <name>E3QYT0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphoinositide phospholipase C</fullName>
            <ecNumber evidence="1">3.1.4.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_11162</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33179"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="ChEBI" id="CHEBI:203600"/>
            <dbReference type="EC" id="3.1.4.11"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.1.4.11" evidence="1"/>
    <dbReference type="EMBL" id="GG697406">
        <property type="protein sequence ID" value="EFQ36018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100038.1">
        <property type="nucleotide sequence ID" value="XM_008101847.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYT0"/>
    <dbReference type="STRING" id="645133.E3QYT0"/>
    <dbReference type="GeneID" id="24416527"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11162"/>
    <dbReference type="eggNOG" id="KOG0169">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002738_3_0_1"/>
    <dbReference type="OrthoDB" id="269822at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004435">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate phospholipase C activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051209">
        <property type="term" value="P:release of sequestered calcium ion into cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08598">
        <property type="entry name" value="PI-PLC1c_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001192">
        <property type="entry name" value="PI-PLC_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001711">
        <property type="entry name" value="PLipase_C_Pinositol-sp_Y"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336:SF82">
        <property type="entry name" value="PHOSPHOINOSITIDE PHOSPHOLIPASE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336">
        <property type="entry name" value="PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00387">
        <property type="entry name" value="PI-PLC-Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00390">
        <property type="entry name" value="PHPHLIPASEC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00148">
        <property type="entry name" value="PLCXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00149">
        <property type="entry name" value="PLCYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50008">
        <property type="entry name" value="PIPLC_Y_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PI-PLC Y-box" evidence="3">
        <location>
            <begin position="329"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU361133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ36018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="551" mass="62621" checksum="9A0F90780D80CDF6" modified="2011-01-11" version="1">MAPTRNGDHYRLDRSPPSLETRTIDNAIHPFGGPKDIDTASSSLPTFDVSPAIQGHLKKRTFDEMRSFRFSISQSSSVTREKLGAFLDSVQGETDAWELLPNDKERYTWPEFFEFWWKTYGLEATRPLESDYKDLDQPLPNYFINSSHNTFLIGNQLASKVDQKAYKTVLRRGCRCIEIDVWNGDALSTTSQEDSRPSTPSKARLPFPKDEPIVTLGWISATPCGFREVCKVIGEYAFEVNDLPVIVSLEVHASVEQQNVMVRIMKEEWGEMLLDKAFEGIDPSFRLPTLRDMKRKIMIKVKKASTLHPGEEDSSRPPATYKPDIATALSDLGIYTFSTRFKSFEMPAAKEPGHIFPMVEHRFLALHATKPREIFSHNKHYFMRVFPNVTRLNNSNPDPSQFWRKGVQMVALNWQHLDEGLMINEAMFANEQGWVLKPNGYRSTDGGTETYIDAAPEGDLDLTVTIIAGQHIWVSDRESTYGENGKNLRPFVKCELHVELGSAHSKAATESDFELKTARTSTKTGHPEWDGGARLKFPKVSRVMEELSFIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYX0</accession>
    <name>E3QYX0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF967 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_11202</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697407">
        <property type="protein sequence ID" value="EFQ36058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100078.1">
        <property type="nucleotide sequence ID" value="XM_008101887.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYX0"/>
    <dbReference type="STRING" id="645133.E3QYX0"/>
    <dbReference type="GeneID" id="24416567"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11202"/>
    <dbReference type="eggNOG" id="ENOG502S03S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101036_1_0_1"/>
    <dbReference type="OrthoDB" id="2209940at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072380">
        <property type="term" value="C:TRC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006620">
        <property type="term" value="P:post-translational protein targeting to endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.150">
        <property type="entry name" value="Haem-degrading domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005624">
        <property type="entry name" value="PduO/GlcC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038084">
        <property type="entry name" value="PduO/GlcC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010371">
        <property type="entry name" value="YBR137W-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28255">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28255:SF1">
        <property type="entry name" value="UPF0303 PROTEIN YBR137W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03928">
        <property type="entry name" value="HbpS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143744">
        <property type="entry name" value="GlcG-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ36058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="201" mass="21886" checksum="05CC1B0686294671" modified="2011-01-11" version="1">MSQKVWTRRNPVGFGLEKSLEAVRSPGAAPVHIPSPPRDVEVLKEDGDSFTLSSFTYEDAFELGHLLHARLLPFALSNGKPTLVSIALANSQQIIFQTSVGPGTLPDNEIWVQRKRNSVLRWGCSTWLLHNKMGGDEKLFASKSGMSREQASKYAIHGGGVPIRVQGVEGVVAVVVVSGLKQDEDHGVIVDVIKSNWQCCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYX6</accession>
    <name>E3QYX6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_11208</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697407">
        <property type="protein sequence ID" value="EFQ36064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100084.1">
        <property type="nucleotide sequence ID" value="XM_008101893.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYX6"/>
    <dbReference type="STRING" id="645133.E3QYX6"/>
    <dbReference type="GeneID" id="24416573"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11208"/>
    <dbReference type="eggNOG" id="ENOG502RY03">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013364_5_2_1"/>
    <dbReference type="OrthoDB" id="425534at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013595">
        <property type="entry name" value="Pept_S33_TAP-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051601">
        <property type="entry name" value="Serine_prot/Carboxylest_S33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248">
        <property type="entry name" value="2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248:SF25">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08386">
        <property type="entry name" value="Abhydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="124"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S33 tripeptidyl aminopeptidase-like C-terminal" evidence="4">
        <location>
            <begin position="465"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ36064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="589" mass="65646" checksum="5E5091C465BB0B42" modified="2011-01-11" version="1">MASKQSPGSLELKGPRANSRTAVIAALSVFALTALIRGGSLLSTPWFPFGHRYVLEQRLSTTDWTWSTIKPSRTLEWHNCFEDGGYDCARLDVPMDWKMPSDDHRVVLAIARIRATNTSDYRGPVIFNPGGPGGSGIWSLRDHGKMLQEIVGTNHDLISFDPRGVGASIPRIECWNSPQQRQSWNLQDPGILESHEGILGELFTRAAAYSQACEKAMKESGILEHTGTTPTARDMLEIVHQTGYDKLKYWGFSYGTILGGVFAAMYPDKVERLVSDGNVDYREWFNSAHLNFVRDTDKVLFAFYDFCSQAGPDKCAFHGPTSEAIMERFSKLLVRLKTHPIIVSADEEKGPEVPMLVTYSKVMRLLYSALYQPQHQFESFSKIIAALEGENGRPFYEHYNPSKPSPTLGCSSQPISPLEPLPQIIEATDDAFPVIMCADHPAVHNLTLEDVRREVDTILELSPATGAVSVPYQMTCNRRTTRPFWRFDGPFEGKTSHPILFIANQADNVTPLISARNNSAGFTGSTVLVQKSYGHTSLAAPSKCTREYIHTYFQNGSLPEDGTECEGDSQPFGPKIGNEVRLYQNQLFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZE8</accession>
    <name>E3QZE8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">MutS domain V</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_11381</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the post-replicative DNA mismatch repair system (MMR).</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Heterodimer of msh2 and msh6.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697415">
        <property type="protein sequence ID" value="EFQ36236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100256.1">
        <property type="nucleotide sequence ID" value="XM_008102065.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZE8"/>
    <dbReference type="STRING" id="645133.E3QZE8"/>
    <dbReference type="GeneID" id="24416745"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11381"/>
    <dbReference type="eggNOG" id="KOG0219">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002472_10_0_1"/>
    <dbReference type="OrthoDB" id="295033at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032301">
        <property type="term" value="C:MutSalpha complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032302">
        <property type="term" value="C:MutSbeta complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000228">
        <property type="term" value="C:nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000406">
        <property type="term" value="F:double-strand/single-strand DNA junction binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000400">
        <property type="term" value="F:four-way junction DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032137">
        <property type="term" value="F:guanine/thymine mispair binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000404">
        <property type="term" value="F:heteroduplex DNA loop binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032138">
        <property type="term" value="F:single base insertion or deletion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000403">
        <property type="term" value="F:Y-form DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007534">
        <property type="term" value="P:gene conversion at mating-type locus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043570">
        <property type="term" value="P:maintenance of DNA repeat elements"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006311">
        <property type="term" value="P:meiotic gene conversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000710">
        <property type="term" value="P:meiotic mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000735">
        <property type="term" value="P:removal of nonhomologous ends"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043111">
        <property type="term" value="P:replication fork arrest"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030466">
        <property type="term" value="P:silent mating-type cassette heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd03285">
        <property type="entry name" value="ABC_MSH2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.110:FF:000002">
        <property type="entry name" value="DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1170.10:FF:000003">
        <property type="entry name" value="DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000523">
        <property type="entry name" value="DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1420.10:FF:000015">
        <property type="entry name" value="DNA mismatch repair protein Msh2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1420.10:FF:000017">
        <property type="entry name" value="DNA mismatch repair protein Msh2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.10">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.110">
        <property type="entry name" value="MutS, connector domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011184">
        <property type="entry name" value="DNA_mismatch_repair_Msh2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007695">
        <property type="entry name" value="DNA_mismatch_repair_MutS-lik_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007861">
        <property type="entry name" value="DNA_mismatch_repair_MutS_clamp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016151">
        <property type="entry name" value="DNA_mismatch_repair_MutS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007860">
        <property type="entry name" value="DNA_mmatch_repair_MutS_con_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032642">
        <property type="entry name" value="Msh2_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036678">
        <property type="entry name" value="MutS_con_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003810">
        <property type="entry name" value="PRK05399.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF35">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MSH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01624">
        <property type="entry name" value="MutS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05188">
        <property type="entry name" value="MutS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05190">
        <property type="entry name" value="MutS_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005813">
        <property type="entry name" value="MSH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="11">
        <location>
            <begin position="733"/>
            <end position="749"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00064337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ36236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="922" mass="103039" checksum="CD2D61E1E2380653" modified="2011-01-11" version="1">MSSRPELKVDDEHGFIRFFKSLPAVHEDTVRIFDRGDWYTSHGEDANFIARTVYKTTSVVRTLGRDDKTGLPSVTMTVTVFRQFLREALFKLGKRIEIWESTGGRMNWQVAKQASPGNLQDVEEDLGGQIEAAPMILAVKISTKATEARSVGVCFADASVRELGVSEFLDNDLFSNFEALLIQLGVRECLVQMDKADKNKDPDLAKLKQIITNCGVAVSERSTSEFGTKDIEQDLARLLKDERATTLLPQTDLKLAMGSAAALIKYLGVLHDPSNFGQYQLYQHDLSQFMKLDAAALKALNLMPGARDGAKSMSLYGLLNHCKTPAGSRLLSQWLKQPLMNKEEIEKRQQLVEAFVNDTELRQTMQEEHLRSVPDLYRLAKRFQRGKANLEDVVRAYQVVIRLPGFLGTLEGVMDEAYRDPLDVAYTTPLRGLSDSLAKLSEMVETTVDLDALDNHEYIIKPEFDDSLRIIRKKLDKLKRDIDQEFSDAARDLRQEVGKKIFLENHKVHGYCMRLTRQEAGAIRNKSGYQECSTQKNGVYFTTKTMQSLRREFDQLSQNYNRTQSSLVSEVVGVAASYSPVLERLAGVLAHLDVIISLAHCSVHAPSEYVRPKIHKRGEGQTILKEARHPCLEMQDDVQFITNDVALTRDKSSFLIITGPNMGGKSTYIRQIGVIALMAQIGCFVPCTEAELTIFDSILARVGASDSQLKGVSTFMAEMLETANILKSATAESLIIIDELGRGTSTYDGFGLAWAISEHIVKEIGCFAMFATHFHELTALADEHPQVHNLHVTAHIGGDGGGKNSKREVTLLYKVDDGVCDQSFGIHVAELVRFPDKVVRMAKRKADELEDFTSKHEDLGLKYSKTDMEEGSAMLKEVLLRWKGEVAGGKMSKEEMVSKLKGLVMANEKLLANPFFQSVKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZI8</accession>
    <name>E3QZI8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_11421</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697416">
        <property type="protein sequence ID" value="EFQ36276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100296.1">
        <property type="nucleotide sequence ID" value="XM_008102105.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZI8"/>
    <dbReference type="GeneID" id="24416785"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11421"/>
    <dbReference type="eggNOG" id="KOG2504">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_1_2_1"/>
    <dbReference type="OrthoDB" id="2213137at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF287">
        <property type="entry name" value="MFS MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="195"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="238"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="276"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="303"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="331"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="361"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="402"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="5">
        <location>
            <begin position="239"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ36276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="429" mass="46254" checksum="87E82DAD8353105F" modified="2011-01-11" version="1">MTTHTENINLESSHHSEPGDSSATSLRPTDKGLAPWLFVFASFVAEAILWGFPLSYGVFQDYYSNHPVLKHDSNIAVIGTVATGVYYLGGPLATPIVARYQAWQRHMIIIGWIGCALSLVIASFATSVPGLIATQGFLYGASFLFVNYPLLRMLNEWFVVRRGLAYGIMSTGAGCSGVAFPFLLESLLSKHGYRITLQVMAVAQFITLLPMIPLLKGRLPASGRGVLQKGDFDFFKQPLFYCFAAANFLEAMGYYIPSLFLPTYATALGLSGTAGALVLALNNLATIFSQLAFGYITDRVNNVFMLVFVSSFIASVATFAIWGFATSLAPLLAFSLLFGLATGGFPCLWNRFGSVLSRDPGHIYSLMAFGKGVGNILSGPISTTLVRGSFEAGYGQGRFAPLILYTGSMMLGSSLGVLGFPLMRKANKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZW2</accession>
    <name>E3QZW2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_11568</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697422">
        <property type="protein sequence ID" value="EFQ36400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100420.1">
        <property type="nucleotide sequence ID" value="XM_008102229.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZW2"/>
    <dbReference type="GeneID" id="24416932"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11568"/>
    <dbReference type="HOGENOM" id="CLU_3399363_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ36400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="31" mass="3334" checksum="B4FA728988CC164E" modified="2011-01-11" version="1">MSRSYSSRGNSTSLIALTVCACRTAGTRNIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZY1</accession>
    <name>E3QZY1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Mitochondrial chaperone BCS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_11547</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family. BCS1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697423">
        <property type="protein sequence ID" value="EFQ36419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100439.1">
        <property type="nucleotide sequence ID" value="XM_008102248.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZY1"/>
    <dbReference type="STRING" id="645133.E3QZY1"/>
    <dbReference type="GeneID" id="24416911"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11547"/>
    <dbReference type="eggNOG" id="KOG0743">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010189_6_2_1"/>
    <dbReference type="OrthoDB" id="10251412at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19510">
        <property type="entry name" value="RecA-like_BCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057495">
        <property type="entry name" value="AAA_lid_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014851">
        <property type="entry name" value="BCS1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050747">
        <property type="entry name" value="Mitochondrial_chaperone_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23070">
        <property type="entry name" value="BCS1 AAA-TYPE ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25426">
        <property type="entry name" value="AAA_lid_BCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08740">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01024">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="BCS1 N-terminal" evidence="13">
        <location>
            <begin position="37"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="12">
        <location>
            <begin position="247"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ36419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="472" mass="50901" checksum="C7AF7A5A09EFAD6D" modified="2011-01-11" version="1">MSSTAPTASTAASASASVLSLDALFNNPLFAGGIGLASLGAAAAFARKGVVVAAGAARRRLLVNVEIGKQDPAYPWILAWLSQPRAPAGFVASRITRIHNLSVSTTTTAQRGAAGPTNAHFFLQPGYGRHIVKHGGAYIAVNREKHSTANMNTGEPHEIVQLTTLWAHRHVFEDIFGEAHALAAKANEGKTIVYAARGMEWAPLGDPRKKRPLGSVILDEGVKEGIVEDVKDFLGRQQWYVDRGIPYRRGYLLFGPPGSGKSSFIQSLAGELDFSVAMINLSEMGMTDDKLAYLLTKLPRRSILLLEDADSAFVNRRQRDADGYSGASVTFSGLLNALDGLAAGEERIAFLTTNHIERLDPALIRPGRVDMMMRIGEATRYQAGQMWDRFYGDVDADGVGRERFLQRLEELGLFGNGTGEAANRSTSTAAIQGLFLFNKNDMQGAIDMAEGLIPRKFEAEDAIPGGAIKTRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3R100</accession>
    <name>E3R100_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NUDIX domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_11935</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697537">
        <property type="protein sequence ID" value="EFQ36788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100808.1">
        <property type="nucleotide sequence ID" value="XM_008102617.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R100"/>
    <dbReference type="STRING" id="645133.E3R100"/>
    <dbReference type="GeneID" id="24417298"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11935"/>
    <dbReference type="eggNOG" id="KOG3041">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062658_0_0_1"/>
    <dbReference type="OrthoDB" id="10249920at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047631">
        <property type="term" value="F:ADP-ribose diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006753">
        <property type="term" value="P:nucleoside phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019693">
        <property type="term" value="P:ribose phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18888">
        <property type="entry name" value="NUDIX_ADPRase_Nudt5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.79.10:FF:000016">
        <property type="entry name" value="ADP-sugar pyrophosphatase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11839:SF26">
        <property type="entry name" value="ADP-RIBOSE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11839">
        <property type="entry name" value="UDP/ADP-SUGAR PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="54"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ36788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="208" mass="23417" checksum="3B44F1481B14C4CD" modified="2011-01-11" version="1">MTAKTQEPVITKTSDLPIEEAKWVTLKKIEYVDQIGKTRTWEVATRKTRGKAGVDAVAMGNILLHPTRPPSTMLVIQYRPPLDAYTVEWPAGLIDAEETAEQAAVREFKEETGYDCRVMSVSPPQAADPGLSNANMQLVMVEAQLGEEEEMPEQRLDDGERIERVIVPLAEFYDRLVEYSKQDRMIVAAKLFHFAAGMNFAKAQKYPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q264</accession>
    <name>E3Q264_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_00309</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089185.1">
        <property type="nucleotide sequence ID" value="XM_008090994.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q264"/>
    <dbReference type="STRING" id="645133.E3Q264"/>
    <dbReference type="GeneID" id="24405674"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00309"/>
    <dbReference type="eggNOG" id="ENOG502TJMC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_469289_0_0_1"/>
    <dbReference type="OrthoDB" id="10003767at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF54">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ25165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="504" mass="56874" checksum="A736C0AC24A51A87" modified="2011-01-11" version="1">MDSAKQRLSKKAKTIVLKALPRERLASRLSQCLDAALASIKGIPLDLPDRVPPPSPLSPVATIPDQTPLSTEAYRASRDRYVRWTPLRNGEYAADWASGCVPTEADVHRMLSWYNTYGVYEFPAVEYVSLIGRGRTNYFFLVEFVPAARPCGRLPQKVVLKFSLPVCPHEKLETEVATMVWAAAATSSSSPSSSSPRLVPRVLAFDSYPRNPLGLEWMMMEPVSGFPLQEYELQGSTDTGLEGFGFPWKTPPQSDKDLMNIGEGIRDFMAKIKVTASGTPKDNCLIGSLRINWQTKSFYTGSIVSPHFYSADRLWRKPVHGPYASVQSYLEDYLSVWRDEYVNDEYMQKRLASLDIVVGRMAKRLEMLPDVKWRLPTDGGRMNGWPVTISHPDPRPNNVLVGEDDRFFQRFGCEYVIDPMQIDMGCALPPRAELLDRVLSRAWPGREASIVLEPVMESTSGIETAFKALMEVCERLPLRRETERVWLDKAVLAMMDQYGQDCTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q265</accession>
    <name>E3Q265_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00310</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089186.1">
        <property type="nucleotide sequence ID" value="XM_008090995.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q265"/>
    <dbReference type="STRING" id="645133.E3Q265"/>
    <dbReference type="GeneID" id="24405675"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00310"/>
    <dbReference type="eggNOG" id="ENOG502S2V9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004184_7_5_1"/>
    <dbReference type="OrthoDB" id="2288928at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26639">
        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="43"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="623" mass="69055" checksum="1405211B3C81872D" modified="2011-01-11" version="1">MPSIYTRRLPSRWIRILALQGGCGDSPIHVRLREANVDSLPSFAALSYVWGDPSQQQQIRVSGHEVFVTKNLFDALRHFRLPDQELMLWADALCINQGDLEERADQVQLMREIYSRAATVLVWLGLDGDEGQAARAIPLMESIHQACEDRARARGVALLAMAHFTPATERLEGLAGVSIPDIAAVAERAGRPGPDPEGWAAIRWVLSRPWFTRVWCVQEIVLARASKVCIGSHSFDWVKLGVTASWLSEQSIASDYDVPPELEGMNWDAAYSMFDTSDLSESSLLEVLVAFRDLVATDPRDKVYGLLGLVSHEALARFPGVDYRKSVAEVYGDVVRASVDSSGTLAPLSYAKHGHEYVRTEIPSWVPRWDASEDVCSILHDFSVTAWENGDKHGLPGLADFEPTADGRVALSGVRFDSIAWVTEMLDIVHFKEDIPSPEAAKHPFLDIWHRASSNNCYVLSASADHPYNGISEMGLTLTAGFTDVYELVGDLGREDLTRFRADFLTYIRQLFDKAGKKPETFNPLDIRLSNGDATRFRIAASRSCDQRRVFETTAGFYGLAPACAREGDVVVLLYGGPVPFVLRQVAEGWVLLGDGFVGPLMPEMAVGSVRERFSHEEVFVLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2X2</accession>
    <name>E3Q2X2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Mitochondrial import inner membrane translocase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_00095</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Heterohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Mitochondrion inner membrane</location>
            <topology evidence="1 12">Peripheral membrane protein</topology>
            <orientation evidence="1 12">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="12">The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the small Tim family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ24951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008088971.1">
        <property type="nucleotide sequence ID" value="XM_008090780.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2X2"/>
    <dbReference type="STRING" id="645133.E3Q2X2"/>
    <dbReference type="GeneID" id="24405460"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00095"/>
    <dbReference type="eggNOG" id="KOG3479">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141397_3_0_1"/>
    <dbReference type="OrthoDB" id="1551503at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.810">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit tim13 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050673">
        <property type="entry name" value="Mito_inner_translocase_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004217">
        <property type="entry name" value="Tim10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035427">
        <property type="entry name" value="Tim10-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13172">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM9B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02953">
        <property type="entry name" value="zf-Tim10_DDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144122">
        <property type="entry name" value="Tim10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0143">Chaperone</keyword>
    <keyword evidence="10 12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 12" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0811">Translocation</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Tim10-like" evidence="13">
        <location>
            <begin position="13"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU367043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ24951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="88" mass="10367" checksum="909B6DB15B5BC013" modified="2011-01-11" version="1">MDALTKTEEAQLQQRLQKRQVKEFMNLFGNLVDHCFTSCIDDFTSKSLSSRETGCITRCIQKQMFSQQRLSERFQEHNAQMTAQMQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q306</accession>
    <name>E3Q306_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00129</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ24985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089005.1">
        <property type="nucleotide sequence ID" value="XM_008090814.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q306"/>
    <dbReference type="STRING" id="645133.E3Q306"/>
    <dbReference type="GeneID" id="24405494"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00129"/>
    <dbReference type="eggNOG" id="ENOG502QUAB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028348_0_0_1"/>
    <dbReference type="OrthoDB" id="5865767at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041681">
        <property type="entry name" value="PH_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37283">
        <property type="entry name" value="PH DOMAIN-CONTAINING PROTEIN YHR131C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37283:SF1">
        <property type="entry name" value="PH DOMAIN-CONTAINING PROTEIN YHR131C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15410">
        <property type="entry name" value="PH_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="81"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ24985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="407" mass="46481" checksum="B0810800AA61F0E4" modified="2011-01-11" version="1">MDSRSHYRGNGPSNTAAQPPPPRRRLSMEEDYFYQEVMTSPLRRPSQPPPYERDARPRRPLASKNNVQHGPVESLPGYSCDIELEGVWVKKMEIENTSKRAEDRNWHTTFVQLRGTALNFYNVKKDWGWGRTRDGPTISPDNPPWVRKASLDKAYSLQHADVGIAADYKKRRYVIRVRAETDQFLLSCIELSTMVKWLEALFAAIDVAAPIDDRDYPRDQSIPRIQRIRWFRGQTPAHTNNYPVPTPRPVSPELHRVASAESPDPFPSSSVLEAILDEPVIDESPIGDGETAIVDTESIYGPGPARNEQISSRLSTTSYPNEAIDPDTGKWAPEHQWTAAHDLLYAKLCYSVLLFKSPRKSNYIISKGKQWFVDWATGRMVRVLPPAYGEIDFFGPWQVIHTENRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q427</accession>
    <name>E3Q427_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Centromere protein Scm3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00483</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089359.1">
        <property type="nucleotide sequence ID" value="XM_008091168.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q427"/>
    <dbReference type="STRING" id="645133.E3Q427"/>
    <dbReference type="GeneID" id="24405848"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00483"/>
    <dbReference type="eggNOG" id="ENOG502SCHT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_302851_0_0_1"/>
    <dbReference type="OrthoDB" id="2420608at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018465">
        <property type="entry name" value="Scm3/HJURP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15992">
        <property type="entry name" value="HOLLIDAY JUNCTION RECOGNITION PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15992:SF5">
        <property type="entry name" value="HOLLIDAY JUNCTION RECOGNITION PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10384">
        <property type="entry name" value="Scm3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="472"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="688"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="796"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="190"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="506"/>
            <end position="516"/>
        </location>
    </feature>
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            <begin position="587"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="610"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="848"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="858"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="977"/>
            <end position="986"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1053" mass="113943" checksum="2CC297B98CD7838B" modified="2011-01-11" version="1">MEPLAKRPRTGPSPLRQQSKEDEDDELNYEPDEVSRMRDPGFQLEQSRAFAAFKLKSTFEHIFQKYERDFTGIGDEIDLRTGEIITDNGHLSSMRNERDTGIPDENEEDEGMLLEEAFSSGDDEEDNDEEDEDDQEDERMLGKKDATPSSTALTQKAKVDLQSCSSLSHTLPASRPESEQRLSNLGPHQSANGNSSSSANPWGREPESVDPTWRVPEINPQQSDDDLIAKLYGARYRFPVSSGSQSVWASRQDSEQEKAASEPARIDMAQLARARQEASRMARQTSKKVLHVFTTDDDKEDDILGVSTADREFRSEKKKEEKKKKRSGEDAAKDQTKTKPPLPDSAAKEPSRHKPRKSSVGEKLTSKKQLVPAKVRKPRKSAQLTESSNQRGEEHLVDVTARLDSTQGLGSIVTGEEAQKRPRQHIVVEIFSKRPPAHEITEVEDSDDMVILDSAPQDTVEALNLSGLAVSEPVSKSPVPRGSPVEAVPDADASVEATSGKTPAPPKEKFFRHEIDPAYAFSDDDDGIPTTRARASRSQKEPTAIPVTEESTKEVFVAGMRPSEETLPSEISGDRQDSEAQPESGAENGNPSSTAGESADPGLHRHEASQAATNIQPASTSQSSRDILDKHQITEQHVTNEINMAGAENAPSTEDVDMQILELLDEIYQETEAHGNTYEGGWEGGSPLENIREDAQSSDVPVDNAREGVRTDIIQGGDGTEEQRPAGDTLQEEDKEVIEPFIVPLGLDEMDGTSTAETDPEPEAMDFELPILTPLEEAPPPTGALSAMPRRGCLSSAFHSGRLENTATSPMRGLKLQSSSPPERHADPGSSPAADAGGPVWPRASVSPKRETTHETQEAAASRSSPALASQAASPEAADAPESPAVGQASPAPKPPRRKRQPKQPSTPSSRRPRIAAKGSSAKISVISLLSDDEDDEKLTPDLFKTRTPGRGDRLLSGDPGGGSPSTPALPAGPQAKTATPAQQHVPSGGRAGSGASTTSRHRKRMAAWAFATPSKAHLGSPSGSLVRTPGGNLRRCGEEGFRCDRDFCFTCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q492</accession>
    <name>E3Q492_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_00548</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089424.1">
        <property type="nucleotide sequence ID" value="XM_008091233.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q492"/>
    <dbReference type="STRING" id="645133.E3Q492"/>
    <dbReference type="GeneID" id="24405913"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00548"/>
    <dbReference type="eggNOG" id="ENOG502SXF6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_374683_0_0_1"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044773">
        <property type="term" value="P:mitotic DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167">
        <property type="entry name" value="OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167:SF24">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE CHK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="69"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="468"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="484"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="494"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ25404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="672" mass="75233" checksum="2C1C8C7D56B22A35" modified="2011-01-11" version="1">MATVRGAKYNKYKDNGTLTGKRYGHAVFDTEPLGLSQPYGARWFSTADVDEAVAEYGQWGQNDHKGYGVSVKKIIGAGRFGIVALVHCINEKGDTLPCVLKLERYRHHVHGTLAREEKALTKFKGAKHILQLLDVTQLIKSERATSYGLYAAGHVAPDPSPQLSDEELDCAWSLDDFACQPIRNFVFVEHAAQGDLNVWLSKASRSRTPWPGLIGMGYPPKEVFGGADRPEWNSNEPIDEHLPDDYPMSEYYPPQQTTHFDLEPSNILASSNVENGNMPIFKIADFGSVQFFGEYATNPAYFDKELFWKCRFSGKGNYFTPEQFTRQWDHLDLQTYLADDNLPNHFVAVDGTKPPVAGNYGMHSNIFQVGVIIWCAITLCAFQPLTAMNYRLPDGQEIVTWGGALQNERFNGVDEELRGLVQRCMADDPVQRPSLGLLMRIIEDRLGANDLGSEEAVATWAQEFFSSPRNLKDNGRKRRHPGGDDNDNDDEDGDSRRHAPRQRLEAEPMIHAAFQQPRRVSNALNQRPRVQHGALALRPASGANQGMSGSNEAEAVDPRVFQVLQVPQMPEWQGISAFGAQPNVFDFNFGAQMPQMPQMPQMPQMPQMPQMPQVPLQWQDISQFGVQPDAFDFGGQQMQQNVGAASFQPGGYFNVHAQYGENPFQPPPQQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4I9</accession>
    <name>E3Q4I9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_01148</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ26004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090024.1">
        <property type="nucleotide sequence ID" value="XM_008091833.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4I9"/>
    <dbReference type="STRING" id="645133.E3Q4I9"/>
    <dbReference type="GeneID" id="24406513"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01148"/>
    <dbReference type="eggNOG" id="ENOG502RB26">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1885605_0_0_1"/>
    <dbReference type="OrthoDB" id="4799051at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179399" evidence="2">
        <location>
            <begin position="20"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ26004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="135" mass="14292" checksum="1A96F6C399CE8785" modified="2011-01-11" version="1">MRAQTLLAAIVACASVVSAAPVAVEAYGPPISPHIISKKDTVEAYGPPLNPHIPAVESKRETTEAYGPPTNPHIISKKDTVEAYGPPVNPHIPAVESRRDGVEAYGPPTNPHIITKKDVVEAYGPPISPHIIAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4T7</accession>
    <name>E3Q4T7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_01246</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EFQ26102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_008091931.1"/>
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    </dbReference>
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    <dbReference type="OrthoDB" id="3553547at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
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            <begin position="191"/>
            <end position="225"/>
        </location>
    </feature>
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        <location>
            <begin position="496"/>
            <end position="531"/>
        </location>
    </feature>
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            <end position="114"/>
        </location>
    </feature>
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            <begin position="200"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="502"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="EFQ26102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="531" mass="60876" checksum="61135149B83F61ED" modified="2011-01-11" version="1">MDADYFDHQNRTTFPPLLPSAKGRTFEQGRKQLTDSITNKVSRLEISQSSVPSLVASDASSAASVASIEDDGVQELWIQMKERRQRLNLIKENMTTKRKALQELRRRKDEADNTFMHMLRPILVRGRQGLPGMSNELLDKRFAEMQSLRTEYHWLESGYEEHEFALDEQEVELIKIETRFFSLLAAGSGRNIRSAPHTDDSEDSEAEESTDIPYELTGISRNGPTDDSHPLWEDLVSAVGDLSNAREEYDDLLLYHSQYTYSMDVKRSARKPPSAEEIEFMDEFPEEEREKRQHVDHLTEEVDRLKEICKQKGAMKKHPSFKIAYALDPNIGDDLSLDSPPPESKTLAHWQFPELLSCPDHVLRPEPLTALDELKRAAKNPLDSPARNLQLCAAQKEYSISKLITEFKGEDKSDFITRWLLHQLRTSPLAVELLYSTFTQTIRLKIKNFRRWQQDVLFHWWRDSAVKPPDEFFGPLTGSGRVWPGHEAIPEHISEPLGHGMQFSTPPRASTENWTGGNGQAYEDTSWPSAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4Z1</accession>
    <name>E3Q4Z1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sec7 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_01300</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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            <end position="689"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="2">
        <location>
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        </location>
    </feature>
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        </source>
    </evidence>
    <sequence length="1531" mass="169790" checksum="AEDF9FEDBAAE490B" modified="2011-01-11" version="1">MPFLRRRGNVVSETDMRRHSILDTESVPQLPPLPQHFPPQHPEPQQQQQQQQQQQPPRPQSQQLQKQPVDPQPQEVSQSQPLLPLSQEQLPEVQQELLEKEQAQHGDEPRRSVSASIQELQSTLLAVPAQSDGNANKSVPPILDDPDTRPDTPPIQDETTKHRRFSILRFRNASDSQLSLRVKQQAEKPPPVPRPPEIITTAPTLELQIPQKKQSRMRLADRFRRSGEIPRNSEDGGARAMTWKSSSRRKTVLEDLTSRNRPTLVTFEEPGRPSSSRAPTNGERHDVPNLSLPANRASESSRSDASSGEHLYTPNTTGNSPPTVPGSSFFRLPRRKNKVVAPLFDLSHLPQKGKSTHGNDGAMTTPSSLDASQPNVASTSRENTPRPQQGSRPQSSYSACADSVASSAQDQSTKPNASAATAFFRPGSIHSGQSSPTRVRLQRRGRSSTMSSLGRESTDGHLDPGTGRTSTSIGRKSFGDLFGLNRLRQNSDLGQGRQGSLTPATPGSSTSKNNSLQIAREPIALPEKFEDETPVKYLGRIEEILSRGVIASALSKGSDPFSIAVLRSYMRRFSFFEYPMDMAIRKLLMEAELPKETQQIDRCLQAFANRYHECNPGIYASPDQAYFVAFSLLILHTDVFNKNNKHKMQQPDYLKNTQGEGVSDSILKCFYDNITYTPFIHVEDDLDLSSDRLLANRAKRKTLFPGGTPETVARRSTRELLDPYTLIIDGKLDILRPSLKDVMELEDHYNYLGTANDLNVKELQRTFFRTGVLQIVSARSRPDAFRDDKGSTNPAEAAQGVVDIKITKVGLLWRKDTKKKKTRSPWQEWGAILTGAQLYFFRNTTWIKNLMHQYETHVKQGFDGEPITFKPPLPEFKPDGYLPTKEAVALVDATYKKHKNAFKYSQPSGYVEEVLLADNEEEMNDWLAKLNYAAAFTTSGVRMRGVVGGNYEGQSRRGIRRLGSSASAQVIQTPTGDVSIVRGKIDHKEAESIQAQRRQTMMDAVAKADEEIGLKEQELEVHLRNARHLQILSPIQAKTRDQILSAAAHMDVKIKWIRMDIWKSRCHRDVLLKDLAEEQSMQGLALSKAHNGHEPREVSPSRERLSIFGAETTNSVARRRRRSSAAVSTIQGSSKAPQAEPESPATEAYQTPPTSATFSPHKHQNSWDSKISKPLEHLQHERPGSSSSHSSTEPTFYSPKQHSTPKKDKGVEQSATDDPHNDVDANERVLLEQAGLLDSGSRGRVLLERNRTGSLSEAGDASESRDAPGSIDKQDKTKIRRSLQRTLRESAGHLSHHRSRKGKEILLSGGSDDTGREDVLTRGTGSFVVHGKKASVINFGSELQQLTPEERMRHRKQDQRDEPPSPTTLDEDFRDALDTSSVPNERRESAASASTATARSFRELHRKYSSAHAPKPPVFGGRLSVPSDGESEAAVSISEGRRTPLPPIENESGDEEETQVPVDGSQPIASTQSFPSPQLIVSPQPIPVALASPLVNSESTSAPEHQQNEGGDGEGAEMQRLPSPPVQAVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q506</accession>
    <name>E3Q506_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00916</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089792.1">
        <property type="nucleotide sequence ID" value="XM_008091601.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q506"/>
    <dbReference type="GeneID" id="24406281"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00916"/>
    <dbReference type="eggNOG" id="ENOG502RR41">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1180133_0_0_1"/>
    <dbReference type="OrthoDB" id="3501153at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053008">
        <property type="entry name" value="Phomopsin_biosynth_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35896">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35896:SF3">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="241" mass="27470" checksum="B1119D16D0701B45" modified="2011-01-11" version="1">MMPWQREALDGGVSYADLGSETETETAPRKRPARFVLNKTCTCLLLILFVLGMTVLYSTLHAAVLQCYASSIGRPRIDLSGYLCAPNGASVEVATQRGCDWDPISFHWYPRERVQDPDNQELIRGFLEAGPWHRFYDAEGTVEVDPDNRVLTTLWLSKREHVVHCMYTLRQTHLWLAKGFDPPFNYSHTIHCTSYLTNIILESPVPDMDKLTVHAVPYPPDWQIVSAYPYMVPKPRLGLCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q627</accession>
    <name>E3Q627_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fumarylacetoacetate hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_01419</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAH family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090295.1">
        <property type="nucleotide sequence ID" value="XM_008092104.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q627"/>
    <dbReference type="STRING" id="645133.E3Q627"/>
    <dbReference type="GeneID" id="24406784"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01419"/>
    <dbReference type="eggNOG" id="KOG1535">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028458_5_0_1"/>
    <dbReference type="OrthoDB" id="74910at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018773">
        <property type="term" value="F:acetylpyruvate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050163">
        <property type="term" value="F:oxaloacetate tautomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006107">
        <property type="term" value="P:oxaloacetate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.850.10:FF:000003">
        <property type="entry name" value="Fumarylacetoacetate hydrolase domain-containing 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="entry name" value="Fumarylacetoacetase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11820">
        <property type="entry name" value="ACYLPYRUVASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11820:SF7">
        <property type="entry name" value="ACYLPYRUVASE FAHD1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="FAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumarylacetoacetase-like C-terminal" evidence="3">
        <location>
            <begin position="20"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ26275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="241" mass="26148" checksum="09D5675326C49088" modified="2011-01-11" version="1">MSLVFRRSMATAASLKKAGKVMCIGRNYADHIKELNSARPKQPFFFLKPTSSILLPGAGPVLRPKGVDMHYEVELALIMGKQVKDLSPDDYKGAIDAIEAYALAIDMTARNTQNEAKKKGLPWSIAKGFDTFLPMSDIVKKSAIPDPHDIELFLKVNNETKQDASTNLMLFPIPRILSDISKVMTLEAGDIVLTGTPAGVGPAVPGDIIHAGLRVNGKELPEAKIEVGVEESPSSYQFAET</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6H5</accession>
    <name>E3Q6H5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_01567</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008092252.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6H5"/>
    <dbReference type="GeneID" id="24406932"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01567"/>
    <dbReference type="eggNOG" id="ENOG502T3D7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_158153_0_0_1"/>
    <dbReference type="OrthoDB" id="5121433at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="92" mass="10261" checksum="879AFCCD8655C8B7" modified="2011-01-11" version="1">MAAGSAKLQTPRSEAGASAADDGKAAPSWNSKKSREEFESLKSKLLDQRFDPKHFPDPLLPRNGSDPRNNPKGTPEAERRIDRIIAEYRDRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6K0</accession>
    <name>E3Q6K0_COLGM</name>
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        <submittedName>
            <fullName evidence="3">WH2 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_01592</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EFQ26448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090468.1">
        <property type="nucleotide sequence ID" value="XM_008092277.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6K0"/>
    <dbReference type="STRING" id="645133.E3Q6K0"/>
    <dbReference type="GeneID" id="24406957"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01592"/>
    <dbReference type="eggNOG" id="ENOG502RXF7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049614_0_0_1"/>
    <dbReference type="OrthoDB" id="2430277at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003124">
        <property type="entry name" value="WH2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02205">
        <property type="entry name" value="WH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51082">
        <property type="entry name" value="WH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WH2" evidence="2">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
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            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <begin position="249"/>
            <end position="258"/>
        </location>
    </feature>
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            <end position="320"/>
        </location>
    </feature>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
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            <end position="364"/>
        </location>
    </feature>
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            <begin position="365"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ26448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="459" mass="44782" checksum="89A8B8B0C6D4371A" modified="2011-01-11" version="1">MPPPPPPPPPMPMMGGPPPPPPPPGGPPGAGALPAKPPAGANRGALLSDITKGKALKKAVTNDRSAPIVGKPSGGSGGPPIGGAPPVPGAGGLPKSPSGLAPPVPGNRARSNSDESGRESTPAPSVDAAPQLAGLFAGGMPKLRKTRGAVDTGASADSSYLSDHENNVRSSSAPRPPTFGAPKPPGGAAPAPPGRPSLPPPNAAPALPPSIANLRKTTGDVPRPNSSASMKGPPPPIGKKPPPLPASRKPSTALSSHPPQLPGVSAPGAPPPPPPSAAPAPPPSAPPSAPPPPPAAAAPRAPVPSPPSRSPAPPPPPPASNGPSPLAMQAALRAAGQASPSAAPPPPPSNAPLPPAAHPPPTAPPSRARAGSGLRSSMLDPSAFTLAPNGAKSPSPTRSNTTAGLHAGGGGGGQRYIVQDPRWKFQDEAMLPKPRDFVGGPRRYRAGRGSSVPLDLSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6L0</accession>
    <name>E3Q6L0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_01602</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090478.1">
        <property type="nucleotide sequence ID" value="XM_008092287.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6L0"/>
    <dbReference type="GeneID" id="24406967"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01602"/>
    <dbReference type="eggNOG" id="ENOG502T4KU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1094199_0_0_1"/>
    <dbReference type="OrthoDB" id="4849350at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178243" evidence="1">
        <location>
            <begin position="17"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="251" mass="25007" checksum="5CE43209333C0108" modified="2011-01-11" version="1">MKSTLIVTALFGAAIASPVAIANVEAPGVEKRDVEPRLLGALINPIRVSATLSIPASTALPSVLTSVVPSVVPTTDVVTLLTVILRSILLNARNINTGLGGGLSVPDTPTLPNNPVATVANGAITNDELRNFIDEIVTQVQVAIGIGRNLSPSLGAGQLRSATGIFDTIKDVLAGLGPVSTITSPNGVSGASVPLNLGPLTDAVSGILDTVGQLLGGLLGGGGLLGGVGNFLSSLLGNNGRNDLLGSLPVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7L6</accession>
    <name>E3Q7L6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_02674</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090874.1">
        <property type="nucleotide sequence ID" value="XM_008092683.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7L6"/>
    <dbReference type="GeneID" id="24408039"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02674"/>
    <dbReference type="HOGENOM" id="CLU_1610628_0_0_1"/>
    <dbReference type="OrthoDB" id="5244249at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="77"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="118"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ26854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="165" mass="17724" checksum="79C6EA3693A32F3B" modified="2011-01-11" version="1">MDDYSRGHLWAEHETNPAPEVMVHSAPEAVQIPLNNLPTRNDGADDARRVHPDGDVALPNHADQTSQSKLKRRSRLWTWKTIIGICIGLLILAIVIPVMVTVVASDRGHGPGNIETTASSPASQASSYFVTPTPSSATSYPSSTLNPVSKTPSIEVLLAIANLQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q830</accession>
    <name>E3Q830_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">WW domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_02213</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091062.1">
        <property type="nucleotide sequence ID" value="XM_008092871.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q830"/>
    <dbReference type="STRING" id="645133.E3Q830"/>
    <dbReference type="GeneID" id="24407578"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02213"/>
    <dbReference type="eggNOG" id="ENOG502SFBG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061843_0_0_1"/>
    <dbReference type="OrthoDB" id="2444812at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="103"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ27042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="304" mass="32555" checksum="60EFB8EA820FEA52" modified="2011-01-11" version="1">MAPDSTRFVSSPRKAEPEQNRPADGQANDEQPTEQGPATPPESDGNDSNSNSKRQSSSPESGEASSTASPAPANDINEKPASSSNAPPLPNEAPPLPSEPAPATEDDGWDFQWDPTSQAYFFYNRFTGATQWENPRVPVAAASMSATAAVAPGTIPGAAAATTISGPPPLPANDRPPAGGYNPAIHGDYDPNAWYAKGSTAEENEANHASSAAYAAEYGAVAQFNRFTGQFQTLDDGPDRHTDEAKSRRQMNAFFDVDAAANSHDGRSLKAERSGKKPSKAELKQFKEKRRARKEEKRRAWLRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8C8</accession>
    <name>E3Q8C8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RNA polymerase II-associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_02311</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PAF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091160.1">
        <property type="nucleotide sequence ID" value="XM_008092969.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8C8"/>
    <dbReference type="STRING" id="645133.E3Q8C8"/>
    <dbReference type="GeneID" id="24407676"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02311"/>
    <dbReference type="eggNOG" id="KOG2478">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021991_1_1_1"/>
    <dbReference type="OrthoDB" id="10260285at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016593">
        <property type="term" value="C:Cdc73/Paf1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000993">
        <property type="term" value="F:RNA polymerase II complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007133">
        <property type="entry name" value="RNA_pol_II-assoc_Paf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23188">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23188:SF12">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03985">
        <property type="entry name" value="Paf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="406"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="412"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ27140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="463" mass="51447" checksum="56B5366785312CE4" modified="2011-01-11" version="1">MSSSAPRGGERMIHQDFIARIRYSNALPPPPNPPKLLDIPNTGLASGQYTTPGFASRLAREQPLNIEVDAELGMPLDLVGMPGIFDGDESSIQASSHPPAVHPHDRALLRPLSTLGRAKSNADASVSFLRRTEYISSVAPRKAVATGAFINPKIKRTEKRRSPEPDKDSPAAIRRKIEKSFESAERFLSNPSRHRHPSKPHVHLTSSYPLLPDHDAFPDSGAYVTVKLLTNPVASANKYDRRLLSGLLRPLDRSPEENEAFQAALEAHERDPARNPKPANLMDYSFFLPKTQTTGDNFRAKFDPENPDHDDDSLYTYQSGSNGCFQFSRLRAYETTKETELDHNSKYSEEVILAFNDELSGSKQKAAYYYPVIQRTTIRPQRAKNIARTLSHMDDETQVVNEVEVSVTDPKGAPRENMRRYKEKPIGYVEEVQDPFPSAEGGGEGAAPGTPSDRDADGDEDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8G4</accession>
    <name>E3Q8G4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02347</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091196.1">
        <property type="nucleotide sequence ID" value="XM_008093005.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8G4"/>
    <dbReference type="STRING" id="645133.E3Q8G4"/>
    <dbReference type="GeneID" id="24407712"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02347"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_2_1"/>
    <dbReference type="OrthoDB" id="5327538at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051935">
        <property type="entry name" value="HSDL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42808">
        <property type="entry name" value="HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42808:SF4">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="309" mass="33727" checksum="7680D25592A54313" modified="2011-01-11" version="1">MDDGKQVALVVGASRGIGRQVAIDLAKNGYTVVVAAKTTSDASKTTPFPPDPNSQQSTVSTVAREIHEAGGDATPIAVDVRDQDSVVRMVKQTVERYGRLDVLVYNSGAIWWSSVEDTPPKRFQLMQRVNPEGLYLTLHAALPHLKHRGRGRVVVVSPPIYSRFFRGKTAYAMGKVSMSVLTKGLAMDFARQGLDEMAITSIWPAVAIESAATQKFQAADPGESRDLRRPTIFSDAVLAILRAPAGRVNGELVLDEDFLRDHAGVTDFSKYALVPGARPRRIMPAVLPDLTVREQDDEGKRYDSAKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8G6</accession>
    <name>E3Q8G6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SWR1-complex protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_02349</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SWC5 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091198.1">
        <property type="nucleotide sequence ID" value="XM_008093007.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8G6"/>
    <dbReference type="STRING" id="645133.E3Q8G6"/>
    <dbReference type="GeneID" id="24407714"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02349"/>
    <dbReference type="eggNOG" id="KOG4776">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062474_0_0_1"/>
    <dbReference type="OrthoDB" id="445677at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000812">
        <property type="term" value="C:Swr1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011421">
        <property type="entry name" value="BCNT-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027124">
        <property type="entry name" value="Swc5/CFDP1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48407">
        <property type="entry name" value="CRANIOFACIAL DEVELOPMENT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48407:SF1">
        <property type="entry name" value="CRANIOFACIAL DEVELOPMENT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07572">
        <property type="entry name" value="BCNT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51279">
        <property type="entry name" value="BCNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BCNT-C" evidence="4">
        <location>
            <begin position="270"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="147"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="78"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="117"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="171"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ27178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="351" mass="37546" checksum="A5F1B69705CF52FA" modified="2011-01-11" version="1">MPPDPIVDDEEYESSQDSDFAPEDVVAADGASEASDPETDGEDATAAATKLAKRKRDADGGEAEDAGFENSGDEALIKKAKKKKKRRRKAKDADAAAAPDEEDEGGDGGLVKTRSMRAAEKQERKTAAVSGPVTVDVEAIWAQMLAGQTVTPPTTEDKTTEEADPVGTKKPGAEADATKPDEALGGGDPSDMIRIKRTYNFAGKVHTEEKLVARSSAEAKLYLASLGKDAAADAGGGGEGEEEEPKRVLRKAFRSAFEPVVEVAGQRSDLNLGVAVRIKAREKEAQAKKLNTVEKSKMDWAGFVDKEGLKDELELAGRAKGSYAERQDFLARSEAKREEEARRARLAGRVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8M3</accession>
    <name>E3Q8M3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Conserved oligomeric Golgi complex subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_01882</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091407.1">
        <property type="nucleotide sequence ID" value="XM_008093216.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8M3"/>
    <dbReference type="STRING" id="645133.E3Q8M3"/>
    <dbReference type="GeneID" id="24407247"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01882"/>
    <dbReference type="eggNOG" id="ENOG502QQP3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030042_0_0_1"/>
    <dbReference type="OrthoDB" id="18786at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019465">
        <property type="entry name" value="Cog5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048485">
        <property type="entry name" value="COG5_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049176">
        <property type="entry name" value="COG5_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13228">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13228:SF3">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20649">
        <property type="entry name" value="COG5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10392">
        <property type="entry name" value="COG5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Conserved oligomeric Golgi complex subunit 5 N-terminal" evidence="6">
        <location>
            <begin position="15"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Conserved oligomeric Golgi complex subunit 5 helical" evidence="7">
        <location>
            <begin position="201"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="89"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ27387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="444" mass="48563" checksum="A40A8367DF09A6CC" modified="2011-01-11" version="1">MTTSNQEDPSYIDYEAFLDPAFNPSSFANTLVLATNNPNDVPLDLSTPLSRVLFDTQEIDSHIDSLTSKQAAPLLTYTQEQTASSKRIISELDAQIKSLNDSYKQLEKEVIDKHAEAEEVRQVATRLWETLKLGRSVGRCLQLGRQLEVQHAEVAASSPSAAAAAAAKKEDHRALVRCSHTILSLREMLDNAAPGEEGYGLARVDAIRTLRDAVVAPVERSARETAEKIIRDFAIPDSATFAQGEETKARTVSAMVTLFLLSPAPAPAHKTDRWAPQLLLAALEGYLRSALQSSIASLSRSLTQFSTLERTFAEISARCQNVVALELVLESTKLPTHLLVAAPERQTNMLQPLLAHLETGSLPSYFWRTMAGSLGPRVQEIVNRGGHAGRSLRDSRVTIVDAMRDCVVKGCQMPRALKGKTRGEGNWDREAAVMVGSVLNNLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8T4</accession>
    <name>E3Q8T4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_01943</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091468.1">
        <property type="nucleotide sequence ID" value="XM_008093277.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8T4"/>
    <dbReference type="STRING" id="645133.E3Q8T4"/>
    <dbReference type="GeneID" id="24407308"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01943"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_1_1"/>
    <dbReference type="OrthoDB" id="2241241at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17356">
        <property type="entry name" value="MFS_HXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000044">
        <property type="entry name" value="Hexose transporter Hxt3p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF91">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="40"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="178"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="304"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="338"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="371"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="402"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="448"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="472"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="43"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="538"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ27448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="564" mass="62736" checksum="DC3850017475E6BD" modified="2011-01-11" version="1">MGFSTIEFDKYNPASEKASDARQDLAHLDYSPLKRITGRSWAMGILISMGGMVFGYDTGQISGFLEMPDFLQRFGEAGPDGTYHFSNVRSGLIVGLLSIGTLIGALCAAPIADRFGRRYSISFWCVVTSVGFVIQIAAERAWEQIMMGRFVAGFGVGALSLIVPMFQAETAPPWIRGALVCAYQLFITLGIFLAACFNYGTVSHLEHSSGSWRIVIGLGWLWTIILGLGILAFPETPRFDYRMGNVERAKSTLCRVYGAPENHYSIHIQLEEIESKLRAESKIKGNAVQEFTGMFKAPRMAYRIALGCGLQMFQQLTGANYFFYYGTTIFASVNINSFITQIILNSINFGTTFIGLYIVEHFGRRKSLITGSIWMFVCFLVFASVGHFSLDRVNPQNTVGPGIILIVFACLFILGFATTWGPMVWTIQAELFPSRYRAKAMALSTASNWIWNFCIGFFSPFITGAIDFRYGYVFAGCNLVGAAIVYFFVIEGQGRTLEEIDTMYLERVTAWKSTQWVPPSAEEMNRIRKQAGTELDAIENENAMSSEKSMEPKGSNGASHQERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9N0</accession>
    <name>E3Q9N0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">NAD binding domain of 6-phosphogluconate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_02712</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HIBADH-related family. NP60 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091588.1">
        <property type="nucleotide sequence ID" value="XM_008093397.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9N0"/>
    <dbReference type="STRING" id="645133.E3Q9N0"/>
    <dbReference type="GeneID" id="24408077"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02712"/>
    <dbReference type="eggNOG" id="KOG0409">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035117_5_1_1"/>
    <dbReference type="OrthoDB" id="435038at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029154">
        <property type="entry name" value="HIBADH-like_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015815">
        <property type="entry name" value="HIBADH-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051265">
        <property type="entry name" value="HIBADH-related_NP60_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43580:SF3">
        <property type="entry name" value="6-PHOSPHOGLUCONATE DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G11600)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43580">
        <property type="entry name" value="OXIDOREDUCTASE GLYR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14833">
        <property type="entry name" value="NAD_binding_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000103">
        <property type="entry name" value="HIBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphogluconate dehydrogenase NADP-binding" evidence="5">
        <location>
            <begin position="7"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="3-hydroxyisobutyrate dehydrogenase-like NAD-binding" evidence="6">
        <location>
            <begin position="174"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000103-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ27568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="307" mass="32628" checksum="A17C06F2CDCD02AF" modified="2011-01-11" version="1">MAPRLLWIGLGNIGRGMCKNLVEKSNLDEPLLIYNRTAKRAIALSQSLPAGKTEVTESLGDAITKADIIFTCVANDQAVDEIFAVAVQQDLKGKVFVECSTIAPGTSEAAAKSVLDKGADFVCAPVFGAPAMVAAGNATLVLAGPKASIEKIRPYVRVMATREINMADEPYHKAATLKVLGNTVILGMVEQLAETYVAAEKSGLGTDYVKQFVDALFGGSPYPAYSVRMLEGDYYKRQEPLFAVDLARKDAGHAIAIAKAAGTRLPNIETADKHLQIVKDHAGPSGDIAGIYGAVRKEAGLKFENDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9T9</accession>
    <name>E3Q9T9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nucleolar GTP-binding protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_02771</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">Involved in the biogenesis of the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Nucleus</location>
            <location evidence="2 7">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091647.1">
        <property type="nucleotide sequence ID" value="XM_008093456.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9T9"/>
    <dbReference type="STRING" id="645133.E3Q9T9"/>
    <dbReference type="GeneID" id="24408136"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02771"/>
    <dbReference type="eggNOG" id="KOG1490">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011784_4_1_1"/>
    <dbReference type="OrthoDB" id="415015at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902626">
        <property type="term" value="P:assembly of large subunit precursor of preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000054">
        <property type="term" value="P:ribosomal subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd01897">
        <property type="entry name" value="NOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000496">
        <property type="entry name" value="Nucleolar GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024926">
        <property type="entry name" value="NOG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041623">
        <property type="entry name" value="NOG1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010674">
        <property type="entry name" value="NOG1_Rossman_fold_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012973">
        <property type="entry name" value="NOG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45759">
        <property type="entry name" value="NUCLEOLAR GTP-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06858">
        <property type="entry name" value="NOG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17835">
        <property type="entry name" value="NOG1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08155">
        <property type="entry name" value="NOGCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038919">
        <property type="entry name" value="NOG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="OBG-type G" evidence="9">
        <location>
            <begin position="168"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="545"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="550"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="598"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR038919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ27627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="658" mass="75111" checksum="92C9DC91AED16F5C" modified="2011-01-11" version="1">MKTQWKDLPPVPNSQEFLDIVLSRTQRRLPTQIRSGFKISRIRGFYTRKVKFTQETITEKLGQIIESFPRLNDIHPFHKDLINTLYDADHFKIALGQLSTAKHLIETISRDYVRLLKYGQSLFQCKQLKRAALGRMATLIKRLKDPLVYLDQVRQHLGRLPSIDPNTRTLLVTGFPNVGKSSFLKSVSRADVDVQPYAFTTKSLFVGHFDYNYLRFQCIDTPGILDHPLEEMNTIEMQSVTAIAHLRSAIMYFMDLSEQCGYSIQAQINLFQSIKPLFQNKIVFIVINKIDVVKPEDLDAATQAQLQGLLKSGDVEMLQLSCNTQEGVQHVKNTVCERLIAERVSQKLNAGTNSSGNIGGRLADVMARIHVAQPGTAPLQTFIPEGVKNLKKYSREDPERRRLAKDVEADNGGAGVYSVDMRQDWLLKNPEWKHDKIPEVWNGQNVYDFIDPDIDAKLQALEEEEERLEQEGFYESDEELDDEEEADVLSKAELIREKQALIRNEAKMKKHLKNQAIIPRKLQKVPLSQMDDALDQLGVDTTDIVSRARAQSRPRGRSLGRSRAGTEDVDMMDTDATPKERLRSHSRARSQSRAPIVNRREDGVQDVEDRTKADRLAKLSQKKRNRMARQGEGDRHTTVSLQRHLVAGKRGLGKNQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9W7</accession>
    <name>E3Q9W7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mixed-linked glucanase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_02799</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091675.1">
        <property type="nucleotide sequence ID" value="XM_008093484.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9W7"/>
    <dbReference type="STRING" id="645133.E3Q9W7"/>
    <dbReference type="GeneID" id="24408164"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02799"/>
    <dbReference type="eggNOG" id="ENOG502QUM3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015157_1_0_1"/>
    <dbReference type="OrthoDB" id="192832at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02181">
        <property type="entry name" value="GH16_fungal_Lam16A_glucanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF24">
        <property type="entry name" value="GLYCOSIDASE C21B10.07-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26113">
        <property type="entry name" value="GH16_XgeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00321">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH16" evidence="3">
        <location>
            <begin position="8"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="2">
        <location>
            <begin position="381"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="350"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ27655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="459" mass="49539" checksum="BA4C2E93646DBFEF" modified="2011-01-11" version="1" fragment="single">MAYSLSHSYFGANFISDFNFINYDDPSNGFVRYQSQPDALAKGLYSINPNTKAVTLGVDNTNVYGLDEGRPSLRLESKRQYNHGLFIGDFAHMPPSVCGLWPAFWMYGTDWPVDGEIDIIEGANQATTNIISGHTTQGCRLPDAPQAAGEPLLRDCESPGTTNNAGCNYLPPASQPHTYGDSFNAVGGGVYALEWTSEAIRIWHWPRHGIPSDIVAKTPDPSTWGLPSALFGTSSCEVDRYFRNMSIVIQTNFCGDYAATIWGSDGDTCNQRAPTCVEYVANNPDAFSNAYWEVNYIDVYQPSAVDNAGPAEPTTTTTIKVTSTIYKTVPNPATMMTSIMQNGTVLVSSMSGNPAGPTATAPPSPSTDPIVPGRDPATVGEYAYLGCYGSTTGFQTFLLRASLPDLTVEKCVDLCRPGRYAALRGSECFCAEALDPDTRAEADRGRCDIPCPGNSVQLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9Z4</accession>
    <name>E3Q9Z4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">dolichyl-phosphate beta-glucosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.117</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">GLRG_02826</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a di-trans,poly-cis-dolichyl phosphate + UDP-alpha-D-glucose = a di-trans,poly-cis-dolichyl beta-D-glucosyl phosphate + UDP</text>
            <dbReference type="Rhea" id="RHEA:15401"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19502"/>
            <dbReference type="ChEBI" id="CHEBI:57525"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.4.1.117"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:15402"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 2 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.117" evidence="4"/>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091702.1">
        <property type="nucleotide sequence ID" value="XM_008093511.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9Z4"/>
    <dbReference type="STRING" id="645133.E3Q9Z4"/>
    <dbReference type="GeneID" id="24408191"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02826"/>
    <dbReference type="eggNOG" id="KOG2977">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033536_9_1_1"/>
    <dbReference type="OrthoDB" id="3784at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004581">
        <property type="term" value="F:dolichyl-phosphate beta-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04188">
        <property type="entry name" value="DPG_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035518">
        <property type="entry name" value="DPG_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10859:SF91">
        <property type="entry name" value="DOLICHYL-PHOSPHATE BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10859">
        <property type="entry name" value="GLYCOSYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="15">
        <location>
            <begin position="160"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="134"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00045097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EFQ27682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="399" mass="43546" checksum="C2DD7739360A8274" modified="2011-01-11" version="1">MDQITEASWPTLGVALLILSVIGLLTVFVTLHLLAPKPRAVLPSEKLYLTSSASGKPIQVSAPCWFDRWSAERSVSEARAHLTDPRDVPDSGATIDPADVRLTVVLPAYNEENRILPTLEEAVAYLDENFGRPSSPTKPLFSPTTPHRRTKNPPSEALSGYEILIVDDGSRDNTVNACLEFAQKQSLHDVIRVIKLERNRGKGGAVTHGFRHARGEYVLFADADGATKFSDVGRLIQGCEDVVDGSHRGVAIGSRAHLVGSEAVVKRSALRNFLMRSFHLVLMILTPPATSRLRDTQCGFKLFTRAALPHIIPYMHAEGWIFDIEMLLLAESAPPAPVLGDDGSVIGTSPGIRVAEVPVDWHEVPGSKLSVISDSIKMAIGLAVLRGSWMMGVYRRRLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAA6</accession>
    <name>E3QAA6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tuberous sclerosis 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_02938</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091814.1">
        <property type="nucleotide sequence ID" value="XM_008093623.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAA6"/>
    <dbReference type="STRING" id="645133.E3QAA6"/>
    <dbReference type="GeneID" id="24408303"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02938"/>
    <dbReference type="eggNOG" id="ENOG502R01W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004261_1_0_1"/>
    <dbReference type="OrthoDB" id="6022054at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033596">
        <property type="term" value="C:TSC1-TSC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032007">
        <property type="term" value="P:negative regulation of TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007483">
        <property type="entry name" value="Hamartin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15154">
        <property type="entry name" value="HAMARTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15154:SF2">
        <property type="entry name" value="HAMARTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04388">
        <property type="entry name" value="Hamartin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="426"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="506"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="550"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="651"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="928"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="680"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="739"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="435"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="447"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="464"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="483"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="550"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ27794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="991" mass="111041" checksum="410EC97B1E570550" modified="2011-01-11" version="1">MALSASLKDLSKVLTSFFASPSLPLPDDVAEVIDAYLNKHEKYDDSSAERLQDELLSTWEKQIKDAPAKYAPFLHIFRLLVPAIRAPARLLKWWDMLHNPVLENITREKDLMEESNLATLEVLMLGTPEDDDSSAEPGINPFAKRLLLAWLERYHKIQSESDLNAQSSERTLRQALITYGKKKPKDFLSTLDTCFVRSEFRARVARLLCEFIQSQPPHLHLILQTPLFNNLMRCLQQDTSAAVISVTITALIMILPHMPSSLVPHLPTLFNIYARLLFWDSEWTGIIEPTSDEGDQKSLALPSRWETCHSPPEADEIEIPHLSNYFTILYGLYPINFMDYIRKPQRYLRHANAVNPDELEVQPTEIRHKSERYRQSHLLHPNFYTLTIDSEKTDFGRWMTSEPAEVVAECMALRFSPETFATVDQGHGQALEAHNSPRSDESDRDGLGPALLSGSSLEPVAESWKTTQNPEQDEGASSHTHATSQRQSSLSSQPSHRTSLEAPKADIVADSPTLPPQLVTSPSHTQLQDMLHSNKVIKSGLHQSLANDSVPSLALSHQESAAEKSNSYVPPPLPTVSAPTSVSDGQSQIAHLQRQILLLHNDLNFERYLKQQHMAHIGELRRRQVREAASEAETQNLILTNRTLRKRLEDSKKAEMQTRKESEKSRTLAKKWESDLSAKLRTLREESRKTKTEIQSLKQELQSAREECEKLKKLVCDAEVKELNSKQTMQSIEINAAENDRLKADVERLSTSERNLQAKEGERQAAITSATEAENRAKTLGLQLQAREEELQKTKKLFQAQIGVLNAKLLEAHTGLYSKRTAETKAAVESALAASRAKQAELQKQYTTLMRKYTVLQSQVEENRFSVGSSNSHGRGDLVFCMDGDGEGSMHSTSPVTTRGSHSGLHRVLSDHDFMTYNATPPIMSKPATPVPAGLAHLPPVQSSPLDLDDGAAASPSSAEAKYHGRGGVQNRRKDEKGKKSGVIRGIRGYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAG3</accession>
    <name>E3QAG3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 13">Mannosyl-oligosaccharide glucosidase</fullName>
            <ecNumber evidence="11 13">3.2.1.106</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Glucosidase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">GLRG_02995</name>
    </gene>
    <organism evidence="19">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>N(4)-(alpha-D-Glc-(1-&gt;2)-alpha-D-Glc-(1-&gt;3)-alpha-D-Glc-(1-&gt;3)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] + H2O = N(4)-(alpha-D-Glc-(1-&gt;3)-alpha-D-Glc-(1-&gt;3)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] + beta-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:55988"/>
            <dbReference type="Rhea" id="RHEA-COMP:12806"/>
            <dbReference type="Rhea" id="RHEA-COMP:14355"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15903"/>
            <dbReference type="ChEBI" id="CHEBI:59082"/>
            <dbReference type="ChEBI" id="CHEBI:132537"/>
            <dbReference type="EC" id="3.2.1.106"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="14">Glycan metabolism; N-glycan degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Endoplasmic reticulum membrane</location>
            <topology evidence="1 13">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the glycosyl hydrolase 63 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.106" evidence="11 13"/>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ27851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091871.1">
        <property type="nucleotide sequence ID" value="XM_008093680.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAG3"/>
    <dbReference type="STRING" id="645133.E3QAG3"/>
    <dbReference type="GeneID" id="24408360"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02995"/>
    <dbReference type="eggNOG" id="KOG2161">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007380_1_0_1"/>
    <dbReference type="OrthoDB" id="410058at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098553">
        <property type="term" value="C:lumenal side of endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004573">
        <property type="term" value="F:Glc3Man9GlcNAc2 oligosaccharide glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070880">
        <property type="term" value="P:fungal-type cell wall beta-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006491">
        <property type="term" value="P:N-glycan processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009311">
        <property type="term" value="P:oligosaccharide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.10:FF:000027">
        <property type="entry name" value="Probable mannosyl-oligosaccharide glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.98.110:FF:000003">
        <property type="entry name" value="Probable mannosyl-oligosaccharide glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.110">
        <property type="entry name" value="Glycosyl hydrolase family 63, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031335">
        <property type="entry name" value="Glyco_hydro_63_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031631">
        <property type="entry name" value="Glyco_hydro_63N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038518">
        <property type="entry name" value="Glyco_hydro_63N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004888">
        <property type="entry name" value="Glycoside_hydrolase_63"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10412">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10412:SF11">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03200">
        <property type="entry name" value="Glyco_hydro_63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16923">
        <property type="entry name" value="Glyco_hydro_63N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180276" description="Mannosyl-oligosaccharide glucosidase" evidence="15">
        <location>
            <begin position="27"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 63 N-terminal" evidence="17">
        <location>
            <begin position="48"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 63 C-terminal" evidence="16">
        <location>
            <begin position="313"/>
            <end position="811"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00052431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU368089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU369107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF03200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF16923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EFQ27851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="826" mass="93851" checksum="2FF77B596FBD8D8D" modified="2011-01-11" version="1">MARTTQLAVFITLSLFNIFGSHLVHAADDGPGSASILTSEVGRLNNESLFWGPYKSNLYFGVRSRTPKSLWTGLMWSRVDNYQDVQQGFRYTCEQHEGLHGYGWDEYDARKGGVQSIHDEGNQIDITTSFIKVPGGANGGSWAARIRGVPREGAPADLKTMIHYYIAQEGTEGEIKFAGENDSAGYDGDVAFEGASPELGRYKLVITQGEGKHPHSTHPLADKKHPDQTMVRSLTVSEEVQWQAKGLVFNLIQESVKHVQENYEMKEPPPAYLIYQIDNKPGEGNVHVVQKMFEGAFEFDVIFSSASAGPELTSADVTREIRSVTESFGERFSSVFSLKAPYNADKYRKFAKSMFSNLLGGIGYFHGSQLIDRSYAPEYDEENEGFWEETAAARARKQQELEGPYELFTAVPSRPFFPRGFLWDEGYHLIPIADWDIDLTLEIVKSWFKTMDDDGWIPREQILGPEARSKVPEEFQVQYPHYANPPTLFLIIEGFMERLRKTNGSLPAEKERLGPTESLQTAHLDNVELGEDFLRKLYPFVRTQYDWFRKTQKGDLKTYDREAFSNKEGYRWRGRTETHVLTSGLDDYPRPQPPHPGELHVDLMSWVGLMTKSLMNIADALGMREEVDEFKTTLNAIRRNLNDLHWSEKDGCYCDATIDAYEENSLVCHKGYISLFPFLVGLLDADDPKLGKLLDLLGDEEHLFSPHGLRSLSKQDEFYGTAENYWRSPVWMPINYMAVSQLKNVASQDGPYKAKAADLFTRLRKNLVDTVYNSWEKTGFAWEQYNPETGEGQRTQHFTGWTSLVVKLMAMEDPSKAANGHVRDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAL0</accession>
    <name>E3QAL0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MIF4G like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_03042</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ27898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091918.1">
        <property type="nucleotide sequence ID" value="XM_008093727.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAL0"/>
    <dbReference type="STRING" id="645133.E3QAL0"/>
    <dbReference type="GeneID" id="24408407"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03042"/>
    <dbReference type="eggNOG" id="KOG1104">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013816_0_0_1"/>
    <dbReference type="OrthoDB" id="10252707at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005846">
        <property type="term" value="C:nuclear cap binding complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000339">
        <property type="term" value="F:RNA cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.180:FF:000079">
        <property type="entry name" value="Related to cap binding protein 80 (Cbp80)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.180:FF:000035">
        <property type="entry name" value="snRNA cap binding complex subunit (Gcr3)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.180:FF:000045">
        <property type="entry name" value="snRNA cap binding complex subunit (Gcr3), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027159">
        <property type="entry name" value="CBP80"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015172">
        <property type="entry name" value="MIF4G-like_typ-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015174">
        <property type="entry name" value="MIF4G-like_typ-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12412">
        <property type="entry name" value="CAP BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12412:SF2">
        <property type="entry name" value="NUCLEAR CAP-BINDING PROTEIN SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09088">
        <property type="entry name" value="MIF4G_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09090">
        <property type="entry name" value="MIF4G_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MIF4G-like type 1" evidence="2">
        <location>
            <begin position="328"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="domain" description="MIF4G-like type 2" evidence="3">
        <location>
            <begin position="535"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ27898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="797" mass="89792" checksum="63562FF04C39C145" modified="2011-01-11" version="1">MGDYERRRHGGGGGYNNRKRRYREDDDHDHRQSRRRIDNAPLHVRVRRQLLSLAESPLRRWHEEVQAIAHVVADNAEDTELRESFVGLVLQLSLEQPLKTPFVAGVLLLVNTLKPDIVDEILAKLSATTQEKIQSGEWRDVKLYLKLLACLQSSLDGEGIFPVLEELFGRAVDLQTASSDDTIGTELVKIILLTIPYIMAAAPGQWQQKAADLMDKTEIIASEPHALQALIDPYLSEKEDQPSGSMSVIALLQKQLQREAANGWELSCLPRPWKLPLEEIEAQEKLDNATKHSLPSITVPEKIVAGPRPLFPEVYFSVYGNQDVESVPPVTDIAASLVRDGLVDTINILDFNRNVTARYLIDLDCYFSDTTFVKRATPFDRLRDIETGRSTWKPEDVAVDAVFSQLFQLPTPEHKLVYYHSVLTEACKIAPAAIAPSLGRAIRHMYRNSSRIDLELSQRFIDWFSHHLSNFGFTWKWTEWVDDVFLPDLHPQKAFIIGALDKEIRLSFAQRIKGTLPEPYQPLIGPEKEKDVPDFKFNDDSTPFATEGREIAALLRRKAPDEEFQPIIERIHSLAIERGLDPLVTSTDIFVTAVCWVGSKSLSHVLACIERTKDRLLDVGAASEVAKAQIITAVMSYWAAQPGVAISIVEKLLNYSILLPITVIEWALGGSSHVEGQSSGDALAQPHVFELVFGTVAKVTGRVRQLLTKEAEADEEAKERECKAMRDLFRAMDDALISWASGSKDEMMEEMDGAGQRDALLRRWGERWLRVFRRRSAIEEAFIVEANKEQAVAVDEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAM5</accession>
    <name>E3QAM5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RF-1 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_03057</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ27913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091933.1">
        <property type="nucleotide sequence ID" value="XM_008093742.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAM5"/>
    <dbReference type="STRING" id="645133.E3QAM5"/>
    <dbReference type="GeneID" id="24408422"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03057"/>
    <dbReference type="eggNOG" id="KOG2726">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089470_1_2_1"/>
    <dbReference type="OrthoDB" id="277888at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003747">
        <property type="term" value="F:translation release factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.20:FF:000065">
        <property type="entry name" value="Peptidyl-tRNA hydrolase domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052405">
        <property type="entry name" value="Mito_Transl_Release_Factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46203:SF1">
        <property type="entry name" value="MITOCHONDRIAL TRANSLATION RELEASE FACTOR IN RESCUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46203">
        <property type="entry name" value="PROBABLE PEPTIDE CHAIN RELEASE FACTOR C12ORF65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="Release factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Prokaryotic-type class I peptide chain release factors" evidence="6">
        <location>
            <begin position="50"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="35"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="37"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="127"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="143"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="179"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ27913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="193" mass="21217" checksum="43DD196FA3B48725" modified="2011-01-11" version="1">MRYRCVTARPALQKLKQQPHHLLLVAPFSVSPSAALKKHEMPPRPKPPPDSEIEESYLKGSGPGGQKINKTSSAVQLKHIPTGVVVKSQATRSRTQNRKIAREILAQKLDDLQNGDQSRSAIVGEVKRKKAASASKKSRRKYRQLDEEKAQSETAEAEVKEQHAEDQTNSAPSAHAEPATSTDASPHVQNLKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAS7</accession>
    <name>E3QAS7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dihydrodipicolinate synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_03109</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DapA family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ27965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091985.1">
        <property type="nucleotide sequence ID" value="XM_008093794.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAS7"/>
    <dbReference type="STRING" id="645133.E3QAS7"/>
    <dbReference type="GeneID" id="24408474"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03109"/>
    <dbReference type="eggNOG" id="ENOG502QWNS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049343_0_2_1"/>
    <dbReference type="OrthoDB" id="191315at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008840">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00408">
        <property type="entry name" value="DHDPS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="DIHYDRODIPICOLINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128:SF24">
        <property type="entry name" value="DIHYDRODIPICOLINATE SYNTHETASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_3G11920)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="2">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001365-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001365-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ27965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="325" mass="34490" checksum="0D150B5A989DFB5A" modified="2011-01-11" version="1">MTASNGSNGHATRRALPVGIYAPTMTFFDPDTEDLDIPTIKKHAERLAKAGLAGLVVMGSNGEAVHCTREEKLAVTKATREALDAAGFQSTPIIIGATEGSVRGTIELSKAAKEAGADYSLILPPSYYRAQTDETAIHDYFIAVADESPIPLILYNYPGAVSGIDMDSDLLIKLAAHPNIVGTKFTCGNTGKLTRVALATNAKTPSSEGSGYMAFGGMCDFTAQTLASGGSGIIAGGANVMPKVCVKVWNLYSEGKRDEAIELQKKLSRGDWFLTKAAIAGTKGAIQSYYGYGGFPRRPLKRLDKARTASIEEGIKEVMEIENSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAY3</accession>
    <name>E3QAY3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Dolichyldiphosphatase</fullName>
            <ecNumber evidence="11">3.6.1.43</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_03165</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 11">Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>a di-trans,poly-cis-dolichyl diphosphate + H2O = a di-trans,poly-cis-dolichyl phosphate + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14385"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19506"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57497"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="EC" id="3.6.1.43"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Endoplasmic reticulum membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the dolichyldiphosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.43" evidence="11"/>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ28021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092041.1">
        <property type="nucleotide sequence ID" value="XM_008093850.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAY3"/>
    <dbReference type="STRING" id="645133.E3QAY3"/>
    <dbReference type="GeneID" id="24408530"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03165"/>
    <dbReference type="eggNOG" id="KOG3146">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074922_0_0_1"/>
    <dbReference type="OrthoDB" id="302705at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047874">
        <property type="term" value="F:dolichyldiphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03382">
        <property type="entry name" value="PAP2_dolichyldiphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.144.10:FF:000003">
        <property type="entry name" value="Dolichyldiphosphatase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039667">
        <property type="entry name" value="Dolichyldiphosphatase_PAP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11247:SF1">
        <property type="entry name" value="DOLICHYLDIPHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11247">
        <property type="entry name" value="PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="24"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="95"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="131"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="12">
        <location>
            <begin position="54"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU367078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ28021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="230" mass="26193" checksum="B4A1921AC4E6203E" modified="2011-01-11" version="1">MDQDTRPLASLSLTHVYYDPDDSLSFLCAWLALLPQALCIVYATLIWSTREIEIVLMFAGQLGCEAINFALKRLIKEERPRRIHGKGYGMPSSHAQFVAYWSIFLVLFLLVRHRPTSARRHHQPYSLIERVVVSVAALGIAAAVAWSRVYLDYHTVKQVLVGCLAGSVCAVGWFMVTAIARDFGLLAWVLQTPIARLFRFRDLAVEEDPCQAGWDKWEERRVEADRQKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QB60</accession>
    <name>E3QB60_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mitochondrial import inner membrane translocase subunit TIM50</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_03242</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the TIM23 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TIM50 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ28098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092118.1">
        <property type="nucleotide sequence ID" value="XM_008093927.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QB60"/>
    <dbReference type="STRING" id="645133.E3QB60"/>
    <dbReference type="GeneID" id="24408607"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03242"/>
    <dbReference type="eggNOG" id="KOG1605">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018875_0_1_1"/>
    <dbReference type="OrthoDB" id="1711508at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005744">
        <property type="term" value="C:TIM23 mitochondrial import inner membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="1" id="KW-0653">Protein transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="1" id="KW-0811">Translocation</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="FCP1 homology" evidence="3">
        <location>
            <begin position="111"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="42"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU365079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ28098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="324" mass="35697" checksum="C8142623C7C8D3DA" modified="2011-01-11" version="1">MDMPNMQWWAKPAPTMIAPANQQLSSNGFTIPGLGNVANAPIPASSSRANPLPARPVTADHITNRKGRRTPAGAASVSRDKILAPSAASGGVPDPTPEYMHRAFLPSVVLPTPRPILVVMDLNGTLLHRPNRRQATSFVERPHARRFLQYCLDTFHVVVWSSARPGNVQSMCDQLLLGPHGGGAGGGAQGDRGAYRRRVLAVWGRDRFGLSDADYQLRVQVYKRLDMVWREADVQAAHPDAAYGGRWDQSNTVLVDDSFEKARSEPYNLLQIPEFFGDANEPGYVVPQVHDYLNALCYQSDVSAYMRENPFKVRDDYKLVPAGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBE9</accession>
    <name>E3QBE9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Zinc knuckle</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_03432</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092308.1">
        <property type="nucleotide sequence ID" value="XM_008094117.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBE9"/>
    <dbReference type="STRING" id="645133.E3QBE9"/>
    <dbReference type="GeneID" id="24408797"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03432"/>
    <dbReference type="eggNOG" id="KOG0335">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG3070">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024213_0_0_1"/>
    <dbReference type="OrthoDB" id="8026949at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051714">
        <property type="entry name" value="Znf_CCHC_NABP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23002">
        <property type="entry name" value="ZINC FINGER CCHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="34"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="58"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="79"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="247"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="275"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="298"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="323"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="347"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="367"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="391"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="406"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="444"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ28288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="454" mass="49974" checksum="AD4C9B10D20B0A08" modified="2011-01-11" version="1">MTDDWGTNEIPADDPWNHPKGGDGVGGNGDDRACFNCGQSGHNKADCPERPKGFDGTCRACGQEGHSRRDCPDAPAMTCRICGEEGHIRKDCPQKPADACRNCLEEGHETVECKAPRKIDRGLIPDVDAEKAWEEICEAVEERDGVEAKDAIYKYLKHFPEMTYVELEKAFRGQEIGVYLIATERVLAPTHTNMDLQGNLDKKYTVQYRFSAHPDRQREKATWPSSPEENMTRLEDAGEPVSRLLQKCINCNELGHISKSCPQEAMEKARITITCYNCGEEGHRVRDCPTPRVDKFACKNCGQSGHKVSECTEPRKAGDDVECNKCHEMGHFSRDCPQGGGGGGRACHNCGNEGHISRECPEPRKIKCRNCDADGHLSKDCDKPVDVTRIKCNNCGEMGHKSYRCPNPPKEDVDDFGPPHDASKSAYNEPDTGDAWGAGGDGGASTQDAGNDGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBZ0</accession>
    <name>E3QBZ0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_03369</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092245.1">
        <property type="nucleotide sequence ID" value="XM_008094054.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBZ0"/>
    <dbReference type="GeneID" id="24408734"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03369"/>
    <dbReference type="HOGENOM" id="CLU_2558171_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ28225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="82" mass="8748" checksum="3EA03B086032214A" modified="2011-01-11" version="1">MASDRAGSPQAKRAELASYHNNTSINQTTLFSLSTFDTPHLIALIVTMADPTTAQTPQEKKQDAIVAIDTPAAFDDLLSGNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCD3</accession>
    <name>E3QCD3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_03665</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092541.1">
        <property type="nucleotide sequence ID" value="XM_008094350.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCD3"/>
    <dbReference type="GeneID" id="24409030"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03665"/>
    <dbReference type="eggNOG" id="ENOG502RMTP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2209816_0_0_1"/>
    <dbReference type="OrthoDB" id="4796369at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ28521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="105" mass="12269" checksum="0EF450F958076BA7" modified="2011-01-11" version="1">MKTRLRASSPVEVVNPLLNPPPQISRKYQGALRRLLHAKIGGVREEDKPLIQFIMPTIIRAANDPLMPDPDRFYQDPDYVPDYNSLLRLVQQLRAWYGVRPSFWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCI5</accession>
    <name>E3QCI5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">OPT family small oligopeptide transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_03717</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092593.1">
        <property type="nucleotide sequence ID" value="XM_008094402.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCI5"/>
    <dbReference type="GeneID" id="24409082"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03717"/>
    <dbReference type="eggNOG" id="KOG2262">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004965_1_1_1"/>
    <dbReference type="OrthoDB" id="9986677at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00727">
        <property type="entry name" value="ISP4_OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="218"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="249"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="273"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="316"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="391"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="458"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="517"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="544"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="628"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="670"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="698"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="731"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="778"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="20"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ28573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="837" mass="92931" checksum="4F696DA6C89F843D" modified="2011-01-11" version="1">MPQPSSVKSSGTASEPTMADNDRGPESKAEVEISGREINPATTSSYVDHDPVEDLRQRLSQWGESSVYHGYDDEDEQGSEHELLLDPNLPEEYETRISKVGSTPTAEVDDELAMKREEEEDSPYPEVRAAVRNYDEDVPCNTIRAWTIGLLLVTVGASMNTLFSLRQPSIGLGPLIAQIIAWPIGQGWAKVMPTKQYNTFGLKWSLNPGPFNIKEHSIIVVMAGVSFSVAYATDIILAQLVFYKQDFGIVFQLLLTISTQSLGYGIAGIMRKFLVYPAAMIWPGNLVSVTLMNAMYEANDRPDPSFIGGSMPRYKWFGIITLASFCYYWIPGFLAQFLSIMAFATWIAPNNVVINQLFGGTSGLSLLPLTLDWTQISGFVGSPLIPPWHAIANTLIGVVVFFVIGASIFHYTDVWYAQFLPMSDSGTYDNTGNPYNTTRILTPQLTLDLEAYKNYSPLFISTTFAISYGLSFAAIASLVVYTYLHNGKQIWAQYKNSSKEKPDIHMKLMQKYKEAPTWWYMGLFVIMLGLGFVTVLAYPTNLTWWAFLLAVAISFGFSLPIGIIQAVTNNQIGLNVLTEFIYGYIQPGRPLALMIFKTFGYITMSQSLGFVSDLKFGHYMKIPPRTMFMCQVVATTFSCFIQIAVLNAALKNIPDVCQPHQENKFSCPGGRVFFAASVIWGLIGPARMFSPGQVYSGLFIFFGLGAILPVIFYFAALKWPKSPVKYLMAPLIFGGAGSIPPATPLNYLSWGVVGYIFQHHIRKKHFAWWSRLNYLTSSGLDLGLALSTLVIFLAFTLNGIDPPKWWGNDIVTATMDAQGTAIQSIPAPGMKFGPKTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCK4</accession>
    <name>E3QCK4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Mitochondrial import inner membrane translocase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">GLRG_03736</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIM8-TIM13 complex is non essential and only mediates the import of few proteins, while the predominant TIM9-TIM10 70 kDa complex is crucial and mediates the import of much more proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Heterohexamer; composed of 3 copies of TIM8 and 3 copies of TIM13, named soluble 70 kDa complex. Associates with the TIM22 complex, whose core is composed of TIM22 and TIM54. Interacts with the transmembrane regions of multi-pass transmembrane proteins in transit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Mitochondrion inner membrane</location>
            <topology evidence="1 14">Peripheral membrane protein</topology>
            <orientation evidence="1 14">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="14">The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the small Tim family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092612.1">
        <property type="nucleotide sequence ID" value="XM_008094421.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCK4"/>
    <dbReference type="STRING" id="645133.E3QCK4"/>
    <dbReference type="GeneID" id="24409101"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03736"/>
    <dbReference type="eggNOG" id="KOG1733">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141397_0_1_1"/>
    <dbReference type="OrthoDB" id="7813104at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042719">
        <property type="term" value="C:mitochondrial intermembrane space chaperone complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140318">
        <property type="term" value="F:protein transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045039">
        <property type="term" value="P:protein insertion into mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.810:FF:000001">
        <property type="entry name" value="mitochondrial import inner membrane translocase subunit TIM13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.810">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit tim13 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004217">
        <property type="entry name" value="Tim10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035427">
        <property type="entry name" value="Tim10-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02953">
        <property type="entry name" value="zf-Tim10_DDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144122">
        <property type="entry name" value="Tim10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0143">Chaperone</keyword>
    <keyword evidence="10 14" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 14" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 14" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7 14" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 14" id="KW-0811">Translocation</keyword>
    <keyword evidence="3 14" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Tim10-like" evidence="15">
        <location>
            <begin position="12"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU367043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EFQ28592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="87" mass="9753" checksum="927B1AE4369731A5" modified="2011-01-11" version="1">MDSDSVKRSVMQQVLQEANMANARVLIEKLQENCFEKCVPKPGSSLSSGETTCMTSCMEKYMSAWNQVNLAYINRIKQESVKGNNSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCY8</accession>
    <name>E3QCY8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminotransferase class-V</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_03904</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092780.1">
        <property type="nucleotide sequence ID" value="XM_008094589.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCY8"/>
    <dbReference type="STRING" id="645133.E3QCY8"/>
    <dbReference type="GeneID" id="24409269"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03904"/>
    <dbReference type="eggNOG" id="KOG1549">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003433_2_2_1"/>
    <dbReference type="OrthoDB" id="420046at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43586">
        <property type="entry name" value="CYSTEINE DESULFURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43586:SF21">
        <property type="entry name" value="PYRIDOXAL PHOSPHATE (PLP)-DEPENDENT ASPARTATE AMINOTRANSFERASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="1">
        <location>
            <begin position="22"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ28760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="404" mass="44219" checksum="BB24F3B97122ED1C" modified="2011-01-11" version="1">MSAQLDIAATRAKFPALALDQVFFDNAGGSQTLGTVIDSIRDYLSQTNVQLGASYRVGQQATAAYGEGYQAGAKFINASPDEVVVGASTTQLFRNLAHALAFDKGDEIIVSAVDHEANIASWLDLASRQGLTVKWWKPAGAPNPKLTVENLEPLLSEKTRLVAFTHASNILGTIHDVAAIAAAVHKETPKGLVCVDGVAYAPHRPLDVQALGVDFYAFSFYKVYGPHTAMLYASRSVQDRHMRSLGHFFNPSGSLEGKLGLAGGSYELVSAVPRVLEYLGTPDSEEWKYKVEQERLLQLTLLQYLNGRDDVTVYGETDAGTERRVPTISFRVKGWGAKELVAAVEKDTDFGFRWGHFYSYRLIKEILGLDPADGIVRVSMVHYNSLDEIKSFVAALDEALRTKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QD63</accession>
    <name>E3QD63_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_03979</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092855.1">
        <property type="nucleotide sequence ID" value="XM_008094664.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QD63"/>
    <dbReference type="GeneID" id="24409344"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03979"/>
    <dbReference type="eggNOG" id="ENOG502SNMS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054780_0_0_1"/>
    <dbReference type="OrthoDB" id="5397330at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ28835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="251" mass="27813" checksum="22893CC1793A8B0C" modified="2011-01-11" version="1">MPIRNPFARRPGHAVFSPAGDENLRPDNQNPSHPGFEKQDTVGSKASSSLSVRSSKSQDNGEYKMSVVNDSGVYLPPSPTEEKAPWPRKYLGSGRNSTDTRNDSGEIEHFSISRESFDSYRRSFDITARSPIPQSDFPARQSLDSARYPRLPRSAIDRRADRDLPTADEGFEDVGLDDQKHQQHQPSRMRGLFSRFGDLDHKEPSANSPNSSVTRFLSGAGRKRGQSGQGSELGTIQRPESVASVETTEVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDB5</accession>
    <name>E3QDB5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Serum paraoxonase/arylesterase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_04031</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092907.1">
        <property type="nucleotide sequence ID" value="XM_008094716.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDB5"/>
    <dbReference type="GeneID" id="24409396"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04031"/>
    <dbReference type="eggNOG" id="ENOG502RYG9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033924_3_1_1"/>
    <dbReference type="OrthoDB" id="5307922at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051288">
        <property type="entry name" value="Serum_paraoxonase/arylesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11799">
        <property type="entry name" value="PARAOXONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11799:SF20">
        <property type="entry name" value="SMP-30_GLUCONOLACTONASE_LRE-LIKE REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ28887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="401" mass="43117" checksum="05736C12D1842F73" modified="2011-01-11" version="1">MGFILQTSVIFAVIFGVALQLVLKDPIWLAFGIGKTIQPLSDFPYSCRRIEDPRLQACEDMWLSEATRQLFLACSDPLARQQWMPNAAHFNASGRSTRDAIVVLDIDSPKDDAFEIRTLSDPGFSGTAGDGLLQLVGLTGIDSSKGDKIQLFLVNNRPSVDPVTGELLDQASVGANSTIEVFETGPQAVGMKHIRTFASDNISTPNNIAALSSDAIYFTNDKGASKVGLRAHASPLLGQGDVSFCSVSSGCKRVSERHRYPNGLVRGRDGLIYVPSAMAGGIQVYRVVPEDDGLQRVADIPVPYSIDNLSVDGKGDIYAAVFPRGIEMLQAIEDPLNAKPKSAAVRISKEGEGVYVWEKVIEDGASEVLPGSTVVVHDAKTGRLFFAGIVSTFIAVCEPRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QE43</accession>
    <name>E3QE43_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">STF2-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04275</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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            <begin position="40"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="145"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="145" mass="15849" checksum="AFB0F9298522EDFB" modified="2011-01-11" version="1">MPLLITSAPLTRSHKFNDRDHAGLADGTAAAQEHLPRYFAKHGPVGADPKKVKKNGGGRSNWGNAGEEVVDEDFRFTYARRRTNSSGFADNIGAFKTKFDVNEPEPVFEESVHGPTELDGEELTKTESSESGRSSAYGDDKVTKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3QE59</accession>
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            <fullName evidence="1">Uncharacterized protein</fullName>
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        <name type="common">Maize anthracnose fungus</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EFQ29147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093167.1">
        <property type="nucleotide sequence ID" value="XM_008094976.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QE59"/>
    <dbReference type="GeneID" id="24409656"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04291"/>
    <dbReference type="HOGENOM" id="CLU_2885644_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ29147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="63" mass="6621" checksum="28715EE1C521C73D" modified="2011-01-11" version="1">MPVAGAGSDLNTPPAASIDGLLSLRAGRWCFVIDLRAKGSIRANGKWYRGRRKGHSGLAEAGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEV9</accession>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">GLRG_04559</name>
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    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093435.1">
        <property type="nucleotide sequence ID" value="XM_008095244.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEV9"/>
    <dbReference type="STRING" id="645133.E3QEV9"/>
    <dbReference type="GeneID" id="24409924"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04559"/>
    <dbReference type="eggNOG" id="ENOG502S08D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012261_0_0_1"/>
    <dbReference type="OrthoDB" id="419770at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="422"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="546"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="431"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="443"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="547"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="560"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="575"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="646" mass="70826" checksum="88B5987501B870BA" modified="2011-01-11" version="1">MNPQHSGAATLPKGFRFHDLDHQNPKTPEPFATNEELQPPSPPRPRLRLKRRVASSLAAPTSQFLASVAAADVPIPSIEEPESSGANKQISSMTYPVIHNLGDLDGLGFQKLRGRRFSPPRTPAPGAAPSLSPQRYPNWSIDSAFSSGESTPEFESSRPSTARSTQTSASIFSRFSLMSDDLECISPETDASDHIKQSFFDSFDEPADPPPKPKSKRRKAPWTKAMSDHLWATYLTYLQDPKVTPFRTGKSCIPPHGVCLRVAREAKRSWRGPKGGRKSLNPKSGSNTPTVETCTFLQWPHTCAATRAHLRELCKLKAASSSARTSRFLANSPTPFGRTAARFWNRRSTPARSPSVFAAHDMSMSLTLSTSEAMQPQGPLAQLTKSSPELAQEPMTEPFPLLAVEADKLGIPLGERPRLGSPFMAKSYGPSSTGALAAAASSMPQRQNQSLGRRRTLQSPARLTRSRSNTQKRVGRPRQGSHEPRKTKRPSLVSDLWIEPMPSEALPKTPLEPDVEFSSTDNHSRDDLFVPRTNLAGLFTAPMRIPSSRSQLSDSSDPFLAPPNAPPPRLGSPFPGSNTSFSFPSRLTQPGGLDHGTIRPFATVQQSGDGGSAPPRNLADRLAYIDERLRDLRRRDTNRRRSESPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEZ2</accession>
    <name>E3QEZ2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_04357</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093233.1">
        <property type="nucleotide sequence ID" value="XM_008095042.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEZ2"/>
    <dbReference type="STRING" id="645133.E3QEZ2"/>
    <dbReference type="GeneID" id="24409722"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04357"/>
    <dbReference type="eggNOG" id="ENOG502S9GA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_510932_0_0_1"/>
    <dbReference type="OrthoDB" id="5396937at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="129"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="404"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="521"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="407"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="535"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ29213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="545" mass="62590" checksum="4D1BCE96CAECA665" modified="2011-01-11" version="1">MDPPHITEFASERYFSKLSQLSESPTTHDAQHNHQLRDPPLLPPQPFSTPPLPSHTAPPSSFILPLRTSKANESEVDFPRSSDQKRPEKSRLFSLRSKVSILHAKSSTSQTDPHEPTAGFLRPKTQSFGQLFLALPTELQIQVISSLPLTDVLNLRRVSKSWHAIVTLNEAPIVRHHLERHIPAYALRLYPSNDPSSANFHHLCGLWHRLHVAAKLSFLMCEWITKEIFLRTTEVQRLEFAPQRERMRRRLIPLLFTVFHFFETYRKLHLQHILDHNGHGLLQVPYTLNPIEVEIMNMYDDQTLLRVHQVFPLIISSFCRRLRPPSYAGRVERSLRGYLKERPSDEVHVAILCVGGLRQVERLWEIKGYNSRRGAVDTWYNSIAKDSTEPTVKQRRSIIGLSRKKSTVSVKDSSKSTQQEGFPARRGSRTSLEDPVDPYDTNLVFNTSLAAGMPMGPLGREHVRHILADLPSLQEIWLKTAEAMILERGIVERTQDIKRNAQVMLELIRDDGMDEEDEWWYGRSTPESIRPPLEAIDEDPMDSGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3QF31</accession>
    <name>E3QF31_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_04613</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093489.1">
        <property type="nucleotide sequence ID" value="XM_008095298.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QF31"/>
    <dbReference type="STRING" id="645133.E3QF31"/>
    <dbReference type="GeneID" id="24409978"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04613"/>
    <dbReference type="eggNOG" id="ENOG502SIM3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021917_0_0_1"/>
    <dbReference type="OrthoDB" id="5422841at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="230"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="277"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="402"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="231"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="292"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="517"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ29469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="540" mass="58852" checksum="1CE3379E38E12B2C" modified="2011-01-11" version="1">MAHAQDSQEPHKRKRDADDSGAQPAHSDRIPQPPPPQSGNASIINYLSKANPGRLKLIQGEPDTFSDVLGLLNQYEGVLNRHESLAANLGAKLTGPRLLKAMEGAFEGPIITNPPPAYGAAPLGWLDIVTFAKTNPEKFILTTGHDGERTCQFYLNGVQVQILEDDWRLIMNGALDRFSSVSTAPLEEDETAEVATLEIVEQRLQVLIKKADEIAKRARQLNYHLSGRRAGISSRHGGQQGSSSAFQPVNHSRGHVPHGSGYDLHADLLQQFLSSSQAYPPRVPSSAGLETALSTGQHTPPATNPHPHSLPLQGRPAVVHAPVIPQRDSSYDPSSAHRGIITARIEKLNKGDQIWPPCDRCRRLKSPCIKHLTACQGCTKKHAKCGWKTITEEEIAWFNREGSSSADETHVEPIPAHPVPARLLRYDPTQDDGRSNEPPPPSNNLIPAGDVSRPASRGQQEHRQRSPLDPGSRSRTSSFMDVEHEPPPPNQKPWIPESQRGEQLPSIKRDLLLSHMASAATAAADARDANSTPASTMAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QF36</accession>
    <name>E3QF36_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04618</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093494.1">
        <property type="nucleotide sequence ID" value="XM_008095303.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QF36"/>
    <dbReference type="GeneID" id="24409983"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04618"/>
    <dbReference type="eggNOG" id="ENOG502T357">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025527_0_0_1"/>
    <dbReference type="OrthoDB" id="3594971at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="500"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="524" mass="60466" checksum="852FA053A86FCE59" modified="2011-01-11" version="1">MATASSLRAAPHKWSLNGLSSELIALIFEQLREIDDRALAAARCLSRRFEAIATPITYRTLCLNERIVALDADSRYPNLLCNVSTYTNHVIARSDLDPDGIRRVLDRVQRLKTVRWHYVDAEFRSGRLWLPSDLLHPQQTRFRGTKLFVEDLPLREFEGQLRDTYIRAIPTDLLVSLKLASPAPPLTTRLNSLKQFLLLSRRLETFHYEDRGQGTNFKFAEGERMPPLKDLVLKSYDWNHSKEDTRLHWDFTQLESLDLISVPIINFLTAVDFTHLAGLRRLHCEDFSAHLADRRQEATGGLYLLVAHHIRALQTLSVTCHIQLFPLDGILRHGASLQLLRFRDHVGFGDEDRRCPTLWAEDIATLARGLPFVHTLELDMDVALCDPTEFLRAICSFRSLQTLILHVQTVLHPLEVVYPGIDRDYDAALRTFQFLLREKQLATPHVPWKQITINVGGWRKVMVRRFSTAWRQQNENGVYAERCFVLEKNEYGQMAFREEMSVEGRSSTPTPDPPTPNFETEYEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QF88</accession>
    <name>E3QF88_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Exosome complex protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_04670</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for exosome-dependent processing of pre-rRNA and small nucleolar RNA (snRNA) precursors. Involved in processing of 35S pre-rRNA at the A0, A1 and A2 sites.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the C1D family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093546.1">
        <property type="nucleotide sequence ID" value="XM_008095355.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QF88"/>
    <dbReference type="STRING" id="645133.E3QF88"/>
    <dbReference type="GeneID" id="24410035"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04670"/>
    <dbReference type="eggNOG" id="KOG4835">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064339_3_1_1"/>
    <dbReference type="OrthoDB" id="1421013at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000178">
        <property type="term" value="C:exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000460">
        <property type="term" value="P:maturation of 5.8S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011082">
        <property type="entry name" value="Exosome-assoc_fac/DNA_repair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007146">
        <property type="entry name" value="Sas10/Utp3/C1D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15341:SF3">
        <property type="entry name" value="NUCLEAR NUCLEIC ACID-BINDING PROTEIN C1D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15341">
        <property type="entry name" value="SUN-COR STEROID HORMONE RECEPTOR CO-REPRESSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04000">
        <property type="entry name" value="Sas10_Utp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 6" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="134"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="165"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ29526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="178" mass="19897" checksum="2CA5F18B80FE128E" modified="2011-01-11" version="1">MALKDMTHDLEKLDSHIDSLEDALKPLIDGLPEMANELPLLDKAKMFALTAYAIESLLFSSLRLQGVDAKDHQVMTELKRVQQYFGKIKKAEEVPAQRTMTVNTEAATRILKADLGENDKSLKKKLEEKLAEERAKALLNSMQRPKRPAPESPPASSSGPEKKLRSSKRKSTGRNSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFY0</accession>
    <name>E3QFY0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Plasma membrane proteolipid 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_04959</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0057 (PMP3) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093835.1">
        <property type="nucleotide sequence ID" value="XM_008095644.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFY0"/>
    <dbReference type="GeneID" id="24410324"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04959"/>
    <dbReference type="eggNOG" id="KOG1773">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107649_1_0_1"/>
    <dbReference type="OrthoDB" id="2152119at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000612">
        <property type="entry name" value="PMP3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21659">
        <property type="entry name" value="HYDROPHOBIC PROTEIN RCI2 LOW TEMPERATURE AND SALT RESPONSIVE PROTEIN LTI6 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21659:SF42">
        <property type="entry name" value="UPF0057 MEMBRANE PROTEIN ZK632.10-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01679">
        <property type="entry name" value="Pmp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01309">
        <property type="entry name" value="UPF0057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179698" description="Plasma membrane proteolipid 3" evidence="7">
        <location>
            <begin position="24"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ29815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="96" mass="10246" checksum="66FFBC8551DC6E4A" modified="2011-01-11" version="1">MGAISAVFLILITILIPPVGVYAVAGCGMDLLVNICLTILGYLPGHIHAFYIEYVYYDRKEQAREGRIITGRAPGVYSDNVQSGGHGYGTIAQGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGA8</accession>
    <name>E3QGA8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Hemolysin-III related</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_04848</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ADIPOR family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093724.1">
        <property type="nucleotide sequence ID" value="XM_008095533.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGA8"/>
    <dbReference type="STRING" id="645133.E3QGA8"/>
    <dbReference type="GeneID" id="24410213"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04848"/>
    <dbReference type="eggNOG" id="KOG0748">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023075_3_0_1"/>
    <dbReference type="OrthoDB" id="529367at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038023">
        <property type="term" value="F:signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006882">
        <property type="term" value="P:intracellular zinc ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004254">
        <property type="entry name" value="AdipoR/HlyIII-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855:SF52">
        <property type="entry name" value="ADIPONECTIN RECEPTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855">
        <property type="entry name" value="ADIPOR/PROGESTIN RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03006">
        <property type="entry name" value="HlyIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="220"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR604254-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ29704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="266" mass="28940" checksum="90FDB79E8E051FC4" modified="2011-01-11" version="1">MSAPLSTSALRRRLRTAIEDDSARRRLWSWGSVEEFGRKAERETSLLSWEELLNIYSHVFGAVLFVLLPFYVFGNGIPPRWGIASTADVVVCSVYALGVTVCFVLSAAFHTLMSHSEAVYLSGIKADFHGVLVLMWSSVYPLAHYAFPCSPRTRDAYVALTGLLAALCAAATARPDLGAVDLGHHRAALFAAFGLAAFVLPIGHGAAVDGAGEVWERVGGGWVLATAGFNLVAVLVYWAKFPERWFPRTFDLVGASHQIMHIMVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGM7</accession>
    <name>E3QGM7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytokinesis regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05159</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ30015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094035.1">
        <property type="nucleotide sequence ID" value="XM_008095844.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGM7"/>
    <dbReference type="STRING" id="645133.E3QGM7"/>
    <dbReference type="GeneID" id="24410524"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05159"/>
    <dbReference type="eggNOG" id="ENOG502QX1K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008906_0_0_1"/>
    <dbReference type="OrthoDB" id="19159at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990334">
        <property type="term" value="C:Bfa1-Bub2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044732">
        <property type="term" value="C:mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031578">
        <property type="term" value="P:mitotic spindle orientation checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034586">
        <property type="entry name" value="Bfa1/Byr4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35140">
        <property type="entry name" value="MITOTIC CHECK POINT PROTEIN BFA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35140:SF1">
        <property type="entry name" value="MITOTIC CHECK POINT PROTEIN BFA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="419"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="697"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="737"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="298"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="471"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="500"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="540"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="561"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="586"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="618"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="749"/>
            <end position="764"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="988" mass="109839" checksum="522A071FE62D61A4" modified="2011-01-11" version="1">MEPLRLKPRQPVAEPDIEDWDDDDFQIDTDDLTFRTASTTANLASSRRDSASSHVSLRSDLESNLDEETHVHVPGDDEKSTLDAIAAATQAGIPIPKNVPSSALMGGTIKRLGGRKIKKIMQDDWEDDLVLPDSTQPLRIKPQDGSKFPDMLRQVSGGSTQTSPTKSMKTPPAVSLLDRRESTESTTSTLSGAINLERFRDNDDDDDFFGDGSETIKVSKTRPPKPISLITPPTPQKNDNALDDDFETDFELPSDGKLRLSTRKDIPKTPLVHAEDLDWGEGSLGTRFGGTRRDAHSTRSSSVSAMSPSVSSSFTAESEDETFDGLVLPSGPVNFEERLSRRKLSRSPVRSVEEEPPNLKTPQPRKEPEPEDMFDGLDVGDGDVFNSGKLTLHRNIRVNSNRPLSPQRPKTAISLTFSTKTTTSRLPRPSHERHERALSALEPVSESGGPIFARSRRSQSRMGHASQSSVTSIHSMPTPTTPSPGSLLPSTPRRRELGPRTSTTSLRNEPTTTSSQLLRFKRSLPAMKASHSPAKPISSRFDRPPSRTDPNRPASAMRPKTPTERSRPAVESHAAQQRRPFLPAGASQSQSQHVTAKTSRTFRHHDSENSLDMRPTSRAFSRSTMRSPSPKRLNRHSDHITHDGLSFRTLTKPHRTRNFGDGHELDGFDDLPTSAQSEAKFVRQPLKAPLRNKLYQNVLPDRTTTPSPAPHSPAKTDYTPHFARDTQASRIARETSLAQRTPSGPLPPFTSSRVSQLSSRNNFNPGLPQASVRSKKKRNPPQLKPHLISNMNKDKTPQHLQGMFYNPDTYRWEGNENVLNAFDIPASSPSTASIPPHIVRDKEVSTPRPALITNISHTKGVQVVGGMVFDPQNMCWLKLGPQTNPKSEISDPMDGFNALDDDEDVFKDIPDLDDNSGDSKEPGRVSEVKDEWLVGEEFDVGPEFVRRQREEEDRWRKKCEKWLGVGDQDRDASRWAIRDILLHQRAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGV9</accession>
    <name>E3QGV9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7514 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_05241</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ30097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094117.1">
        <property type="nucleotide sequence ID" value="XM_008095926.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGV9"/>
    <dbReference type="STRING" id="645133.E3QGV9"/>
    <dbReference type="GeneID" id="24410606"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05241"/>
    <dbReference type="eggNOG" id="ENOG502S6DG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_444105_0_0_1"/>
    <dbReference type="OrthoDB" id="5413703at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055936">
        <property type="entry name" value="DUF7514"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39611:SF1">
        <property type="entry name" value="HYDROXYPROLINE-RICH GLYCOPROTEIN DZ-HRGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39611">
        <property type="entry name" value="HYDROXYPROLINE-RICH GLYCOPROTEIN DZ-HRGP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24355">
        <property type="entry name" value="DUF7514"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7514" evidence="2">
        <location>
            <begin position="240"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="419"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="475"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ30097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="536" mass="58022" checksum="2713FEFD32DCBF31" modified="2011-01-11" version="1">MATKPAEKPVRPRLNTTTDWASPRAAAGYSSGPEEGVSPRSAGKSIREGQEKGHRRGGIEDGRPQQRRHGSESLAMKPSISNLRDNLGDLSPSVVKELKRMIKEEVAQVAQVVQLKKSETDTPANPPRPSPVSSQKAVSTPSSPAPPPSVVEARSSSKVYLPRDRSPMTTHAKTASTIPAPAGQSTSPVSPRPKTVHFQSGGPSVIHYEPCTGSILESISPTAPATAAEAELSSVDKAWGMLFDSEGYSTQRLNSVLRGLASSMIAEFGYPETLVVTPDKMFTLYTRYRIEPEKFPYEDIFKERSEDALKRIEFLYQDLGCPYHLVQAAPRSHPSVPGLTPAGFAKWMVSNILAYPESEARRLHAIVSALPVDADGPLLEGKPERLPRQLSRHLLPRTHDNKVRKILNEAVWDCLEDAAPSLPPTSRTARVSEAAAHSTRRPSTGADDPRDPAPAPHRTTYGERGSDVDYGVYSGHRDGRGSDSRDESPRSPGIGRRSGAGAGSGRRPTWEEMHIRKGSSGGMVSSVDAGPHRSCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QH01</accession>
    <name>E3QH01_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Tat pathway signal sequence</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_05283</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ustYa family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ30139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094159.1">
        <property type="nucleotide sequence ID" value="XM_008095968.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QH01"/>
    <dbReference type="STRING" id="645133.E3QH01"/>
    <dbReference type="GeneID" id="24410648"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05283"/>
    <dbReference type="eggNOG" id="ENOG502T1QG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042941_2_2_1"/>
    <dbReference type="OrthoDB" id="3687641at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043386">
        <property type="term" value="P:mycotoxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365:SF7">
        <property type="entry name" value="TAT PATHWAY SIGNAL SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365">
        <property type="entry name" value="YALI0B05434P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ30139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="307" mass="35777" checksum="1E614CDAF79B6DBA" modified="2011-01-11" version="1">MNLLKWHLNLSFREPRYEIMNEENDSEAGSEDQLLAEKGSRPTRPRAGGFLHGLGGPFLWLHVLFLTFYSALFFTLVLARQGQEHACADDQTMVWSPAREALRPEKVLFGNEIQDDNVFRGHPRPELDAAWNTLIQYSNVKVKAEDLRRINRTSVRLHDESGELTEYYWSGLNVHHQLHCLKMVRQAVFPEYYFKGKKPPRHLEGHIDHCIDNIRMTLMCKADISLGSYDWVDNNRRPLTNFHTEHSCYNWDLVNNWARDHSFDMYDNTSLVHPFLGKSYPLDSDGKYIFTEEVDPFEGNKITPPPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHM1</accession>
    <name>E3QHM1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_05503</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697349">
        <property type="protein sequence ID" value="EFQ30359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094379.1">
        <property type="nucleotide sequence ID" value="XM_008096188.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHM1"/>
    <dbReference type="STRING" id="645133.E3QHM1"/>
    <dbReference type="GeneID" id="24410868"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05503"/>
    <dbReference type="eggNOG" id="ENOG502RAV5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_569865_0_0_1"/>
    <dbReference type="OrthoDB" id="2943660at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="222"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="369"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="247"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="282"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="315"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ30359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="438" mass="48688" checksum="EA62E70F4D007B58" modified="2011-01-11" version="1">MKDVQRQRDAVLKALTAPGQARVLRRLRTGAQRERDAALEALAAPGQAHDVLRRLQSGEKLDSIYDHFEMYGSASPTTSQLSDTSNQLQNINEEASLTPTQMTIDSPRTLSHTNSAVPEGPETSHIHSAVKGQDSVSNCAEDEPDRLVPHLQTPTLSNATLTNGIDAHPDADRMPEVPLGMFMEQNTPMIFPNPYCPDRAYPTDSIGNIFWWHSDISDPMQPNYGAPPSTDPYVGPYQQFTAPYIPSQGQDSYPQPISTLPPVPDKSPPISRSSSQERPHYSAASSTTTTTIGESRYPTPPPTKKRKLPTRDNVSSTTSGTGSRSRSNTFVPEEKTANKKPSNQQHSSRERERHRRASARNWQRQKQQTAELEAVMKFAESRNRELHREYAEVLRQVVDVKNALMDHAKCNNPGINSWLHSQATNIHFTTAVNLIVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHP7</accession>
    <name>E3QHP7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05529</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697349">
        <property type="protein sequence ID" value="EFQ30385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094405.1">
        <property type="nucleotide sequence ID" value="XM_008096214.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHP7"/>
    <dbReference type="STRING" id="645133.E3QHP7"/>
    <dbReference type="GeneID" id="24410894"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05529"/>
    <dbReference type="eggNOG" id="ENOG502SX1S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072359_0_0_1"/>
    <dbReference type="OrthoDB" id="10057496at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="254" mass="26959" checksum="5382D54D099E6FBF" modified="2011-01-11" version="1">MSNPITGHDADPRRPIFSPTNGMPIQRYGDAYIPHGGWAGAYGGGAAPGYGNYYLYQPSPYSYPAAAAATAAPVPYPGSTAYTWPNSQPGTYGTYPLQPGGQGSYAARAAQGLPALDPRNPAAQLSNSTGGTGCEPGYNYFFPAAHTKIHVFRTAQPPWQLPANARVPFAAFHVPVGTTLAELLRGFGASNPNPKKNKCFEIVQAGNGRWYKGLCFSGDDKDMMKKCVADVGWDAGRTGLPGQKPVVCVWLVKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIF7</accession>
    <name>E3QIF7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05711</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094587.1">
        <property type="nucleotide sequence ID" value="XM_008096396.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIF7"/>
    <dbReference type="STRING" id="645133.E3QIF7"/>
    <dbReference type="GeneID" id="24411076"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05711"/>
    <dbReference type="eggNOG" id="KOG2741">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028866_0_0_1"/>
    <dbReference type="OrthoDB" id="64915at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006740">
        <property type="term" value="P:NADPH regeneration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840:SF7">
        <property type="entry name" value="BINDING ROSSMANN FOLD OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G10190)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="1">
        <location>
            <begin position="14"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="376" mass="42168" checksum="4DD78E1F7C80432B" modified="2011-01-11" version="1">MGELSNNSELRKVLKVGIIGLGEVAQVSHILVLNNLSSYYEITYICDVSQQALDHCVKKVAGGTPKTTSSPEELISSPDTDVIVICNVNAFHPAQTILALQHNKYVFVEKPLALNYHDLDAIIAAEKTSEAKVFVGYQRRYAEAFVDALKEVGGMSKIDYIRVRDIIGQNRSFVGQSGTYPVKYADYSVEEAADMHSTEEEMVKAALVDEMGVTATPESMTMFRLFTGLGVHDFSALREMVGMPSRVVGASLGLPIWNVLFQYQDFPVMYESGIIDVPRFDAHLEIYSREKIVRVDYDTPYVKGLPVTMTIRERIESARGDGYQERTIRKTYEDPFTLEFLEFHSCATKKTSPKTSAMDSREDLDLIKMIMQSAYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIK6</accession>
    <name>E3QIK6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcription initiation factor IIF subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_05760</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the TFIIF alpha subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094636.1">
        <property type="nucleotide sequence ID" value="XM_008096445.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIK6"/>
    <dbReference type="STRING" id="645133.E3QIK6"/>
    <dbReference type="GeneID" id="24411125"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05760"/>
    <dbReference type="eggNOG" id="KOG2393">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025955_0_0_1"/>
    <dbReference type="OrthoDB" id="76676at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005674">
        <property type="term" value="C:transcription factor TFIIF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001096">
        <property type="term" value="F:TFIIF-class transcription factor complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032968">
        <property type="term" value="P:positive regulation of transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008851">
        <property type="entry name" value="TFIIF-alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011039">
        <property type="entry name" value="TFIIF_interaction"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13011:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13011">
        <property type="entry name" value="TFIIF-ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05793">
        <property type="entry name" value="TFIIF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50916">
        <property type="entry name" value="Rap30/74 interaction domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="350"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="17"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="51"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="75"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="151"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="207"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="356"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="368"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="392"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="411"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="472"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="502"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="534"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="556"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ30616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="708" mass="78700" checksum="E406E6ED596947F6" modified="2011-01-11" version="1">MSAPPPGLPNGQNPNGQQPPQPAQPGQPRPPPIKRRPRGDPLVARKRPGALRPPAPRPPLGARPSPGAAGHHGLQRPETEDDIKARRAANGGWLDPAPQNVREFKIVTTKKALRDGVRHHVMKLSSAKADLEKRGIDPTNQEEFTRPVTLQRRDPRQPPPGREVKQEQAEPQPLDEKEAERLAQIKADREAVRAIELAKSAPSLKDPNADKKPKPKEKEKDVQFHRQPRSEKEKKQQELRYEEALPWHLEDADGKNVWVGSYVAPLSETTVCFVATRDGKFAAIPLEKWYKFTAKPHFNTMRLEEAEALMSKKTDVGRWYMRDKQKKSEQEEWEATRHALYGPAKIKTESSTFRAASREEKMDHDQIDMEGDEFQDDDENPGLEQDNDEEYKEANDRIRRDQLGANLFGEADERRVEKEMDELRKAEEERRKEGKKTQKALIKREKETIYQSDSSGYDPFESSSSDDDSDEEKQKEENKDKEKDDENKDKDKDADGKDKTASGVSSKGNTTPSGRQKHTDALKKGKSLKRPGSPNLSESSGNESSRKKLKKHAATSVHQSRSSTPSAGLKNNLGKGAMSDGEATGGEMSDGQLRKKKIKLVGSGARGTPVGSRAGSPMPATSGSKPGSPLPEGSPAPRAGSPNGPIEAWEIVDALPELPGGISIGNLMRRFQGRIGDGPGQMDRKDWIKLVKENCAYGPDKILRRKPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJ23</accession>
    <name>E3QJ23_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heterokaryon incompatibility protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_06005</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094881.1">
        <property type="nucleotide sequence ID" value="XM_008096690.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJ23"/>
    <dbReference type="STRING" id="645133.E3QJ23"/>
    <dbReference type="GeneID" id="24411370"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06005"/>
    <dbReference type="eggNOG" id="ENOG502SKXB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002639_5_3_1"/>
    <dbReference type="OrthoDB" id="5362512at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF10">
        <property type="entry name" value="TOL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="197"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="603"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="603"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="620"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ30861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="826" mass="91271" checksum="A142D19CD4B95074" modified="2011-01-11" version="1">MICEFCRSTVLESERRWDYHHRHVASFEASVRSGCLFCTRLAKGLGNLSSWFDSDHDINAVYRWNIRQAYSNRDTQSHVSVRFRPVPGRNDGAKRSEHLPDVQFHMYPKDDFVTDLDETNLGTGTDSDQALRQMRAWMDDCVNHHPECTRRHASREFVPTRVLDVGHPGDDDDAAAAWPPSHVRVIDTNKTPIRAPYLTLSHCWGDGAFVQLTADNLGAFTTRGVPWEDDAEGGSRGISSNATFAQALRVVRQLGQRYIWIDSLCIIQGKGSKGAHVEDWKAQAPLMHKVYRNSFCNIAAADSRNHTEGLFRPRLRHGFAPVYYASRTPSRVFGDAVWRVLEHDHWDRGLLSRHLYTRGWVFQERLLSPRLLHFGAGQVFWDCAALSASESLPDGLPAALDDAAAAATHRSWRRQLQGAALSVPSLASSTADSIRGFWKDAVRAYTGCDLTFSSDRLAAVWGVAKLVRDALGEEYGAGLWTNGLHEQLAWRVADDRRASEKGGSAGGGFPSWSWASVKGAVEVAPPVPDLPRFYIASGHDGGALRFLLKNGIFGRFEGEHSASWKEELVIMARKLEETSTKMSRKVAAKASVAFAPILEESSDAKGHEDLDKQPGLGGEEDLKIEGSDAKDPPRGPSQNETGIGRDEPKDSGSTNPGPGSKEVAKKGSNADIPSELLSNEIAIQTHICKGTLQPAAVEDGEWTVAVEGVTQDDAVVEAFPDTLPRESSVPCELLLLAVSREVCDELGDWVPDDGYFEEDDIFGTQYTGSALLVERAGEDRFRRVGAVLFRQLDADSWRSFRRACGQDDEMMEGELDVGDGQKVWLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QK49</accession>
    <name>E3QK49_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_06381</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697354">
        <property type="protein sequence ID" value="EFQ31237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095257.1">
        <property type="nucleotide sequence ID" value="XM_008097066.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QK49"/>
    <dbReference type="STRING" id="645133.E3QK49"/>
    <dbReference type="GeneID" id="24411746"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06381"/>
    <dbReference type="eggNOG" id="ENOG502R8I5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018354_4_2_1"/>
    <dbReference type="OrthoDB" id="9983560at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050432">
        <property type="entry name" value="FAD-linked_Oxidoreductases_BP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878:SF91">
        <property type="entry name" value="FAD BINDING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G12070)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878">
        <property type="entry name" value="GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180645" evidence="3">
        <location>
            <begin position="19"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="4">
        <location>
            <begin position="114"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ31237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="566" mass="60319" checksum="6F893EF1A2B44C7B" modified="2011-01-11" version="1">MRTSYLAVATALVTLTWAAVAPTQQCRCLPGDACWPSTASWEALNATVSGRLVATAPIGSPCHDPTYDAAACEALQSSWSNPLTHIPSSSSVMQSYFANQSCDPFTDRAVPCTLGNYVSYAVDVQGAADVSNALKFAKANNVRVVVRNTGHDFLGRSTGAGALAIWTNHLKSMDFTTWSDEHYSGPAVKVGAGVLGYEVLEAAHAEGLAVVSGECATVGLAGGFIQGGGHSALSTEFGLAADQTLAFEVVTADGETVVASPSQNADLYWALSGGGGGTFGVVTAVTVRAHPEETVGGAAFQLLAASTTPEKFSAAVSKFHELLPAMTDNGAMAVFLHNSQFLALRPLTVWNSTAAHVRDVVLAPFTKALGEMGITLAVAYSELSYRDHYATYMGPLPQGNLEVTRYQFGGRLIPREVIENNNDAYQVVVRNLTANGVLLAGSVGQYNKPAGAPDNSVHPAWRKAVMQLQLITNWDDAAPWADMEDSQKRMTEEFMPLIQSVTPGSASYMNEADFRQPDWQNAFFGDNYAKLLTIKKKYDPESLFYVLKGVGSEAWDVAPNGKMCRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKF0</accession>
    <name>E3QKF0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase family M20/M25/M40</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_06482</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20A family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697354">
        <property type="protein sequence ID" value="EFQ31338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095358.1">
        <property type="nucleotide sequence ID" value="XM_008097167.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKF0"/>
    <dbReference type="STRING" id="645133.E3QKF0"/>
    <dbReference type="GeneID" id="24411847"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06482"/>
    <dbReference type="eggNOG" id="KOG2275">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021802_11_0_1"/>
    <dbReference type="OrthoDB" id="3064516at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000328">
        <property type="term" value="C:fungal-type vacuole lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05674">
        <property type="entry name" value="M20_yscS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.900">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017141">
        <property type="entry name" value="Pept_M20_carboxypep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047177">
        <property type="entry name" value="Pept_M20A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45962">
        <property type="entry name" value="N-FATTY-ACYL-AMINO ACID SYNTHASE/HYDROLASE PM20D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45962:SF1">
        <property type="entry name" value="N-FATTY-ACYL-AMINO ACID SYNTHASE_HYDROLASE PM20D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037217">
        <property type="entry name" value="Carboxypeptidase_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="Bacterial exopeptidase dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178577" evidence="8">
        <location>
            <begin position="19"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="218"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="542"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR037217-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR037217-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ31338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="572" mass="62977" checksum="8E516264D6A9CC80" modified="2011-01-11" version="1">MRSQTLLAFLSSTALASANSPYYPEEQVPFAAAADVGADTTSDFKCDLPPVVSPSDGLPSAKDLFSSPEAIRKQVERHAAIVRVPSICYDDLGDFDTDKRWDVFYDLHHVLKKTYPVFHDRAELVKVNTFGLVYTLRGSDPSLKPLLLAAHQDVVPVADAATWTYPPFSAHFDGEWMWGRGVSDDKNSFTALLSALETLLSGGWSPTRTVILASGFDEECSGRRGAGHIATHLEQTWGNDSMVLVLDEGGMGLQQLDDGTLYALPAVMEKGHVDVWLDLHVIGGHSSVPFPNTGIGIASEMVVALEAHPYSPKLTTGSPLYEHMVCQARYSPDAQPRITELLEEGDLDALAAELVAIDRPTHYRLQTSQSVDYFQAGQKINAMPEKIRVGVNYRVAPQNSILEIQHNVVGYVSAIAKKYGIAVKAFEGDEDYQEYAKRHATKLGSVKELDDAVKPLYDVDYNGTLYLSRTQATQPAPISPTKGPVWDLFSGTLQSTFAFDGGRVVPVGELMTGNTDTRHYLSLTRNVYRFVPIRNGATLNAHTIDERIKISAHMEILSFYYDLIRNFDSADI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKL6</accession>
    <name>E3QKL6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">BZIP family transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_06548</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697355">
        <property type="protein sequence ID" value="EFQ31404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095424.1">
        <property type="nucleotide sequence ID" value="XM_008097233.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKL6"/>
    <dbReference type="STRING" id="645133.E3QKL6"/>
    <dbReference type="GeneID" id="24411913"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06548"/>
    <dbReference type="eggNOG" id="ENOG502S6P7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013452_1_0_1"/>
    <dbReference type="OrthoDB" id="3555317at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40618:SF1">
        <property type="entry name" value="B-ZIP TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40618">
        <property type="entry name" value="B-ZIP TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="3">
        <location>
            <begin position="81"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="160"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="96"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="160"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="184"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ31404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="638" mass="70252" checksum="C05C8A8FD640A1DA" modified="2011-01-11" version="1">MPPNPELKILNAESYNDGKSAFRAPRSLPSGRPRRAAIGDEPPKSKKRTKAQSSEAGELEDEDKKRSRGRPRLDTNDETAKERRRTQIRLAQRAYRNRKETAIQSLEKKVDELRKINEEMSKEFMRIYDFAVSKGMHESTPEFGCQLQATTEKFVALARRSSEELEKDGDLPTSQDNDVDAQEASPTTGNAGLSDTSGSQDVAVKPAEMMYGGFIVSHGEDTAPSTPRFQKLTAMHTTSWAPDSQSQAPHSTPPQAPLGYEIVTEPTTDNASFPFGMSFDDSLDQAGSLNLSGQPFSETLFSILSPPSSYAYQERTFGRRLQRSTLEKAYFLVCMPDPPPAVMSKAFGFCLLFETKDRIKERLANRLRVNERESMFNWKFPFWNLGGGGTWFDATDDETDYSRDGKLRGPVGNQGTAEPHRHNVDSMFGLGPWDARTEETRDLRVNHGAAKLHMSVPGFEGDFYDADEVEWVLRQRGIFIPPAADFVTAEIDPADFSTDTTAGGQVFGTGSQSSVDDILSGLRRAEKSPLAHFARGYVGMNLQPTRASDIDNGSHSVARTEEALPAPKDIDPSLGGDAFGLGEKPANGPSDTGLRKRLVTINVGVLVQEIALRSVCLGRTPGVRPKDVNVAFWASLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLN7</accession>
    <name>E3QLN7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_06750</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697357">
        <property type="protein sequence ID" value="EFQ31775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095795.1">
        <property type="nucleotide sequence ID" value="XM_008097604.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLN7"/>
    <dbReference type="GeneID" id="24412115"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06750"/>
    <dbReference type="eggNOG" id="ENOG502T44D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1001184_0_0_1"/>
    <dbReference type="OrthoDB" id="6359816at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180549" description="BTB domain-containing protein" evidence="2">
        <location>
            <begin position="17"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="BTB" evidence="3">
        <location>
            <begin position="16"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="204"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ31775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="278" mass="31924" checksum="F28E7F5713D9CD35" modified="2011-01-11" version="1">MGCLNLTFLLESGAFADFHLICTDSDGVEKKFSVHKNIVFTQCAKIRDLATIAPIKRGSDGIEFAHLEYDPVPFGAVLHFLYSGEYEAESQPATRKRGESEQDLHDIPQPLFYSLRALKLAHELEIFIMYEEAASALRFSAEYYTHHVDFPSMVDELYGTCGHHAQFDMYLNRIAGLISENSLVDRRFQDRLNPIMLKHPRLALDAMEATFEALAETRRELVRAQEDISDMRAQGFVRDEFWAQAESDRQRDRETKQTTADRFEYRVVRGSLKRSPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLP0</accession>
    <name>E3QLP0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Serine hydroxymethyltransferase</fullName>
            <ecNumber evidence="9">2.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_06753</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Interconversion of serine and glycine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine</text>
            <dbReference type="Rhea" id="RHEA:15481"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 9">Belongs to the SHMT family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.1" evidence="9"/>
    <dbReference type="EMBL" id="GG697357">
        <property type="protein sequence ID" value="EFQ31778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095798.1">
        <property type="nucleotide sequence ID" value="XM_008097607.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLP0"/>
    <dbReference type="STRING" id="645133.E3QLP0"/>
    <dbReference type="GeneID" id="24412118"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06753"/>
    <dbReference type="eggNOG" id="KOG2467">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022477_0_1_1"/>
    <dbReference type="OrthoDB" id="10265628at2759"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004372">
        <property type="term" value="F:glycine hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019264">
        <property type="term" value="P:glycine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00378">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000097">
        <property type="entry name" value="Serine hydroxymethyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00051">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001085">
        <property type="entry name" value="Ser_HO-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049943">
        <property type="entry name" value="Ser_HO-MeTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019798">
        <property type="entry name" value="Ser_HO-MeTrfase_PLP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039429">
        <property type="entry name" value="SHMT-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000586">
        <property type="entry name" value="PRK00011.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680">
        <property type="entry name" value="SERINE HYDROXYMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680:SF28">
        <property type="entry name" value="SERINE HYDROXYMETHYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00464">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000412">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00096">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5 9" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="7 8 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Serine hydroxymethyltransferase-like" evidence="10">
        <location>
            <begin position="24"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8">
        <location>
            <position position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000412-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ31778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="484" mass="52891" checksum="CF80027ED822A86C" modified="2011-01-11" version="1">MAANGSNYSLPVSHKEMLERSLIDSDPEVAQIMKDEIKRQRESIILIASENVTSRAVFDALGSPMSNKYSEGQPGARYYGGNEHIDQIEILCQNRALKAFNLDPSKWGVNVQCLSGSPANLQVYQAIMPVHGRLMGLDLPHGGHLSHGYQTPQKKISAISTYFETMPYRVNLETGIIDYDQLEKNAQLFRPKVLVAGTSAYCRLIDYARMRKIADSVGAYLVVDMAHISGLIAAGVIPSPFEHADIVTTTTHKSLRGPRGAMIFFRKGVRSVDAKTGKETLYDLENPINFSVFPGHQGGPHNHTITALAVALKQAASPDFKAYQQKVIDNAKALENKFKALGHKLVADGTDSHMVLLDLRQFSLDGARVEAVLEQINITCNKNAIPGDKSALTPCGLRIGTPAMTSRGFGEADFERVATYIDESIKICKEVQGSLPKEANKLKDFKATVAGGQVAKINDLRKEVAAWSASFPLPVEGWRVDAGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QM75</accession>
    <name>E3QM75_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein PBDC1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_07107</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PBDC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095983.1">
        <property type="nucleotide sequence ID" value="XM_008097792.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QM75"/>
    <dbReference type="STRING" id="645133.E3QM75"/>
    <dbReference type="GeneID" id="24412472"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07107"/>
    <dbReference type="eggNOG" id="KOG4093">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103791_1_0_1"/>
    <dbReference type="OrthoDB" id="10248897at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051787">
        <property type="term" value="F:misfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990593">
        <property type="term" value="F:nascent polypeptide-associated complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061770">
        <property type="term" value="F:translation elongation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051083">
        <property type="term" value="P:'de novo' cotranslational protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3560.10:FF:000001">
        <property type="entry name" value="Protein PBDC1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3560.10">
        <property type="entry name" value="yst0336 like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023139">
        <property type="entry name" value="PBDC1-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008476">
        <property type="entry name" value="PBDC1_metazoa/fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021148">
        <property type="entry name" value="Polysacc_synth_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13410">
        <property type="entry name" value="PROTEIN PBDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13410:SF9">
        <property type="entry name" value="PROTEIN PBDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04669">
        <property type="entry name" value="PBDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Polysaccharide biosynthesis" evidence="5">
        <location>
            <begin position="20"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00061201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00069779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ31963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="155" mass="18203" checksum="35E8477A6BB200BB" modified="2011-01-11" version="1">MAAPVPTNFNAQDADNLEDIEKQFAVKVVQHMETYWNILEKVKGSSLRLTKIDDEIYEHLQKDFPEFDPSATINEDEMKSKDGKERWRKFMMAYEKKVDDYNFGTMVRANPKFEYGQNEVIFVPRMQFYAVEIARNRKGLNDWIYEKAQAAKASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMM3</accession>
    <name>E3QMM3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HHE domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07255</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096131.1">
        <property type="nucleotide sequence ID" value="XM_008097940.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMM3"/>
    <dbReference type="STRING" id="645133.E3QMM3"/>
    <dbReference type="GeneID" id="24412620"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07255"/>
    <dbReference type="eggNOG" id="ENOG502S054">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079417_0_1_1"/>
    <dbReference type="OrthoDB" id="9983919at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012312">
        <property type="entry name" value="Hemerythrin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35585">
        <property type="entry name" value="HHE DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_4G00730)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35585:SF1">
        <property type="entry name" value="HHE DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_4G00730)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01814">
        <property type="entry name" value="Hemerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hemerythrin-like" evidence="1">
        <location>
            <begin position="47"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="205" mass="23673" checksum="4E2EDB6077CF7A0F" modified="2011-01-11" version="1">MATMFRSSLVFPALSKGFLRPPTKPATCRPCIRQQFYSTPPLLGRLTDVIREDHRDLGAYCKHILEATDMNEQARFQNLFICEELVVYPVLEKHVANGKILADRDRAEHQAVKEKLYWFQERRPEDLDFEPALSSLMEDLRRHIRTEEEEDLMFTPTRSHPSAPNKPPFETVVGLMEAPLDKLRDLFATFPTEEEKAKAKAKADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNC6</accession>
    <name>E3QNC6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Fungal specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_07508</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697361">
        <property type="protein sequence ID" value="EFQ32364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096384.1">
        <property type="nucleotide sequence ID" value="XM_008098193.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNC6"/>
    <dbReference type="STRING" id="645133.E3QNC6"/>
    <dbReference type="GeneID" id="24412873"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07508"/>
    <dbReference type="eggNOG" id="ENOG502QV53">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007003_3_1_1"/>
    <dbReference type="OrthoDB" id="4161332at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF86">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="22"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="62"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ32364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="775" mass="85918" checksum="1E39DD0031C0C7A2" modified="2011-01-11" version="1">MASRSGDSVTASGRPRRRAVEACSFCRRRKIKCNNEQPTCANCKTYGKDCVYEPLASIAEKAAETTPALRRAERRRQSTRRGDRTDLGTPSRIPEDNGVSVSPAEHDGDTPHTPGSNGPATHSTLHTNTRPASLAETDPRAGVSRIVVSANGISSYHGRTSALFEESLQERSAAVDLRPQMSDDWIEKGLVAEAARQRQLEEFNFRAGKLDFDGVDPELGMHLLSLHWNRQHHSFLLTYRPAFMRDMACNGPYFSKILLNAIYFGASKFSPRREVRRDPNDVRTAGWAFRERVRKLLGDALDKSDITTIQALLVMTNSLFALGDERSAAWLYAGLAFRMIIDLGMHVDAPGLGITRKFSDEDLEIRRRVFWGAFVVDKIQSLYQGRPASLKESDTLVPIKFLDTFEEFENWKPFAYSTDATSYPGCPAYSVSTFTCLCRLSVVMSDILSCIYTERAFDKSAAELSIMLENLSSKLAAWKDTLPAHLTFDPKSNCRVPPPHVLSLHAMYHVLTILLHRPFVADGHLYNTSRSISVNSFITCATSANSIVGILRAYDKVFSVRHAPYLISYATYVAATIHVRIAAKRSTESEARERLETCMAVFRENQETNWAVRRAKTIVEGLMTRLGVSLSRVDAGEKYRSNAYPNMDGTSSGVPEARRDAENHETLPRADVLHPPQIVLENTSPPMGWSDIDGIIQSFVRGQDNNAVAMDLSQAELHNQPLPAGPGLQPATFDSSNLMGHQAWFQGMPDGDGGAASFDDLLFGFNGSALDSVFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPC5</accession>
    <name>E3QPC5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Ferric reductase like transmembrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_07857</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ferric reductase (FRE) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697364">
        <property type="protein sequence ID" value="EFQ32713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096733.1">
        <property type="nucleotide sequence ID" value="XM_008098542.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPC5"/>
    <dbReference type="STRING" id="645133.E3QPC5"/>
    <dbReference type="GeneID" id="24413222"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07857"/>
    <dbReference type="eggNOG" id="KOG0039">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010365_3_1_1"/>
    <dbReference type="OrthoDB" id="4494341at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000293">
        <property type="term" value="F:ferric-chelate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015677">
        <property type="term" value="P:copper ion import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF12">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G14340)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="221"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="259"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="290"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="319"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="11">
        <location>
            <begin position="344"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ32713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="628" mass="70857" checksum="2DF166025C5C5F88" modified="2011-01-11" version="1">MDSHRRRLVGLVADLVPTKVLQQRAHAAEGTGAATATSTISPYSSNLDGVNQPVNMLFKDMLWASFGGMAAIVLIITISRILWAQLRHVSAMSVEGERQNYWKTAQWIWMPSLKKHLIYAPLWNKRHNKEIKLSNAIGIGTLPSRMHTFILGFYLASNMVYMFFLNWQNANIYAFCAELRGRSGTLSVVNMVPLIILAGRNNPLIGMLHVSFDTYNLLHRWIGRMSVIEAVLHTIAWLIVQVADGGWDSVWHRMSNQLFIGSGMAGTIALVVIMILSFSPVRHAFYETFLNVHIILAFFIFLMTYIHCAVAGMPGGLPQLPWMIAIFTLWFLERMARIVRVAYMNWSDRGVTDAIVEAVPGECTRVTMNLPRYVDVKPGTHAYLRFKDIRPWDCHPFSIGWVEHIPDHRAVHLDEEKAQSACIDKKNTTTSISFIIGAHTGFTRDLYNVARQSGDRAIRMKAVVEGPYSGHHSLDSYGHAVLFAGATGITHAISYLKPLIDGYNNGSVATRRITLVWIVRDYEALEWVRPWMDTVLRLPNRKDILRIQLYITRPQNSQQIVSASNTVQMFPGRPNIPLLMKREVSEQQGAMCVHICGPGALADDVRAAVREVQDEGTVVDFVEESFTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPG1</accession>
    <name>E3QPG1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Extradiol ring-cleavage dioxygenase class III enzyme subunit B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_07893</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697364">
        <property type="protein sequence ID" value="EFQ32749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096769.1">
        <property type="nucleotide sequence ID" value="XM_008098578.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPG1"/>
    <dbReference type="GeneID" id="24413258"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07893"/>
    <dbReference type="eggNOG" id="ENOG502QS66">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046582_1_0_1"/>
    <dbReference type="OrthoDB" id="7396853at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07363">
        <property type="entry name" value="45_DOPA_Dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.830.10">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014436">
        <property type="entry name" value="Extradiol_dOase_DODA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004183">
        <property type="entry name" value="Xdiol_dOase_suB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30096">
        <property type="entry name" value="4,5-DOPA DIOXYGENASE EXTRADIOL-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30096:SF0">
        <property type="entry name" value="4,5-DOPA DIOXYGENASE EXTRADIOL-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02900">
        <property type="entry name" value="LigB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006157">
        <property type="entry name" value="Doxgns_DODA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53213">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180676" description="Extradiol ring-cleavage dioxygenase class III enzyme subunit B domain-containing protein" evidence="6">
        <location>
            <begin position="19"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="Extradiol ring-cleavage dioxygenase class III enzyme subunit B" evidence="7">
        <location>
            <begin position="62"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ32749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="322" mass="34826" checksum="E718B4D1AC2AD963" modified="2011-01-11" version="1">MPRLTPLFLLSLLVALTAYLVSPTLRSFLETASAAIANHTSHSPESATVKRPRMPVYFFSHGGPDVMHNTSHPVFPVLQPIGAEITSLRPAAVVVFSAHWQSPVPASVLVNAAPSAPLIYDFSGFPPHYYAATYPNVGSPALAARVCALLVADGEISCSRTHRGLDHGVWAGFHVAFHPDENPLRVPLVQVSLLRGEDPDAHYRLGRAVSALRDEGVVVIAAGMSVHNLHHMGSGPEPLPYAVSFDDALKEAAEAGAHERQRKMSQLCRRPDARQAHPWMDHLMPVHVAAGAAGDDLGRQLWTMKEGSFAWAQYRFGSGPKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPM0</accession>
    <name>E3QPM0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ATP adenylyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_07941</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697365">
        <property type="protein sequence ID" value="EFQ32797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096817.1">
        <property type="nucleotide sequence ID" value="XM_008098626.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPM0"/>
    <dbReference type="STRING" id="645133.E3QPM0"/>
    <dbReference type="GeneID" id="24413306"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07941"/>
    <dbReference type="eggNOG" id="ENOG502QRAQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049915_2_1_1"/>
    <dbReference type="OrthoDB" id="10267950at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003877">
        <property type="term" value="F:ATP:ADP adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009163">
        <property type="entry name" value="Ap4A_phos1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043171">
        <property type="entry name" value="Ap4A_phos1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045759">
        <property type="entry name" value="Ap4A_phos1/2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019200">
        <property type="entry name" value="ATP_adenylylTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38420:SF3">
        <property type="entry name" value="5',5'''-P-1,P-4-TETRAPHOSPHATE PHOSPHORYLASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38420">
        <property type="entry name" value="AP-4-A PHOSPHORYLASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19327">
        <property type="entry name" value="Ap4A_phos_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09830">
        <property type="entry name" value="ATP_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ap4A phosphorylase 1/2 N-terminal" evidence="3">
        <location>
            <begin position="6"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="ATP adenylyltransferase C-terminal" evidence="2">
        <location>
            <begin position="199"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ32797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="335" mass="36636" checksum="143DE3C22D430A94" modified="2011-01-11" version="1">MSPIKAPVNLPELVRAAFNKARSNGDLTYYATQVTVLHANSIPFQLRFSPALANKPTASRSKSDEPRKPFDPFESPEKGPLFIVDLPDSGHNLVLNKFAVVPEHFILATKEFKQQTHLLEPRDLAATYACIEAYRQYGHGHEGRDGELYAFFNSGPHSGASQPHRHIQLLPVARMRDGLPEDSRWDVLAKRLGSSDASGVPFSTFADKIHRDMTPEEMHSIYLSLFNLAVEAVTAQIGTVNDPRDGDGDAPISYNLAMTSDRLVVLPRLAEGAKINQDGTPVGELCLNGTVLAGTALVKNEAEWNVLKAKNDGVQLLEILSKIGLAVDGGHSRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQA8</accession>
    <name>E3QQA8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Histone chaperone RTT106/FACT complex subunit SPT16-like middle domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_08190</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Histones H3 and H4 chaperone involved in the nucleosome formation and heterochromatin silencing. Required for the deposition of H3K56ac-carrying H3-H4 complex onto newly-replicated DNA. Plays a role in the transcriptional regulation of the cell-cycle dependent histone genes by creating a repressive structure at the core histone gene promoter.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Interacts with histones H3 and H4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RTT106 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697367">
        <property type="protein sequence ID" value="EFQ33046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097066.1">
        <property type="nucleotide sequence ID" value="XM_008098875.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQA8"/>
    <dbReference type="STRING" id="645133.E3QQA8"/>
    <dbReference type="GeneID" id="24413555"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08190"/>
    <dbReference type="eggNOG" id="ENOG502R9PE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033828_0_0_1"/>
    <dbReference type="OrthoDB" id="75754at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013719">
        <property type="entry name" value="RTT106/SPT16-like_middle_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050454">
        <property type="entry name" value="RTT106/SSRP1_HistChap/FACT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45849">
        <property type="entry name" value="FACT COMPLEX SUBUNIT SSRP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45849:SF3">
        <property type="entry name" value="HISTONE CHAPERONE RTT106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08512">
        <property type="entry name" value="Rttp106-like_middle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01287">
        <property type="entry name" value="Rtt106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histone chaperone RTT106/FACT complex subunit SPT16-like middle" evidence="5">
        <location>
            <begin position="254"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="48"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="364"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="397"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00037550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ33046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="445" mass="49025" checksum="540B5B391D104B40" modified="2011-01-11" version="1">MPAGLDSQQLDAVFQSRPDILQGIKKAADTPARIALFNNIANFVHEQINGPEPASKRRRVDEGPTNGFKATNKNDATPNAAPKSTGTGTGNAADEEVLLEIKEISVSVPQRKKYDLCFTANHLYARVPNTTAPVEGIVYAWEDIEYAFYLPVPEKTQVQHNYVLFPRGTCLPTKTSPEKEALVFTVPFTPPKQGTIGGPRASAASAVSDTYRALFDWALTTHLSSAGNRAEIVAADPSKFHSLVRQPHRPIEKAVHVKAFRGSKDGYLFFLPNGIFYGFKKPLVFLPIDRIVAFSYTNVLQRTFNIVVEVFTEGDAKEEIEFGMLDQEDYAGIDESYVKRHGLQDRSMAEQRKAKMELTENLKAKKAADAEAGANGDVDDNGMTELEKAQLEAEQALQEDEDEDEEDYDPGSEGESEGSGSSDDDDDDDDDDEAEGDEDDEMAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQQ0</accession>
    <name>E3QQQ0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RBR-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_08332</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.31"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.3.2.31" evidence="2"/>
    <dbReference type="EMBL" id="GG697368">
        <property type="protein sequence ID" value="EFQ33188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097208.1">
        <property type="nucleotide sequence ID" value="XM_008099017.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQQ0"/>
    <dbReference type="STRING" id="645133.E3QQQ0"/>
    <dbReference type="GeneID" id="24413697"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08332"/>
    <dbReference type="eggNOG" id="KOG1812">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015887_0_0_1"/>
    <dbReference type="OrthoDB" id="9977870at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20335">
        <property type="entry name" value="BRcat_RBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22584">
        <property type="entry name" value="Rcat_RBR_unk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031127">
        <property type="entry name" value="E3_UB_ligase_RBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002867">
        <property type="entry name" value="IBR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11685">
        <property type="entry name" value="RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01485">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="12">
        <location>
            <begin position="281"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="11">
        <location>
            <begin position="285"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="502"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="712"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="112"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="176"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="213"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="236"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="247"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="503"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ33188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="764" mass="87303" checksum="F4B5BEE8674C7794" modified="2011-01-11" version="1">MPATPNTPPYRRGRVPVDDGYDSYDEEPSSSGREREREASRRGLSPRSSHHSRTLRIRESRQSLRYSQSASETDSDDESESSVSTQEEKRERRRDRNRQEREIYSKPSRQTVVERRRPAEDDKTPKRRMKIKKIIYMEEEDGSTEATPRQSTDERSRSLSRHRSHTSRPASERHYSSHHSHSPARRSGHHHRPLSSSKRLAREVYQTRGDSELTPTRISIRHPSQTVYPKTRTIRRSNTVSGASQVTSRTRSTTSSNRRSSSFLGNLLTGSSVSHSSDKTARVECVVCMDEFSSSKVAKLKCGHRMCSVCLKRHFKISITDPQEMPPKCCSENIALKHVDHLFSADFKKKWNRKFQEYSARNRIYCPSRKCGAWIKPHYIRKEGGRKYGKCGQCRTKVCCSCNGRWHPSRECPNDEETTRFLDQAKDEGWKRCYKCHHMVELKEGCNHMTCRCGAQFCMVCGTKWKSCDCPWFNYETGNADQLYDMQVPAAIQHMERLDLAQSSRSMRPSVAPSAPRSRSQEYDSRLMRRFQENRDEDVARTLQSYEIDDVYDGGYGDIVDVGNTAGHFMNDDYRRELDTFVAAPVPPAPTPPAAFERPAPTDYMSGVNRARGMPPDALGQRLAERFSEFRSSPGAPRPGMMAPPPVPPLGPMTAPPMGPLPMSAPMVMGPPPPLPLLRRHTIEEEMYNRTTRPSERVVPGRMVHDYEREAAVHAPRSRRRMREEPKSSTLAGLTGMGRGMNRVHEWRNHVQPGMPEGERAAMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRF6</accession>
    <name>E3QRF6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08723</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697370">
        <property type="protein sequence ID" value="EFQ33444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097464.1">
        <property type="nucleotide sequence ID" value="XM_008099273.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRF6"/>
    <dbReference type="GeneID" id="24414088"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08723"/>
    <dbReference type="HOGENOM" id="CLU_2621897_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ33444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="78" mass="8568" checksum="11135CD08912C3A6" modified="2011-01-11" version="1">MSAPHPRMRTGRGGTWTGTWTGTWTGTWTASFEEWAEKQPVPSWSAALGGPVMRYALAPIEGIIDKSIFKVESSTRAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRV6</accession>
    <name>E3QRV6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_08523</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697372">
        <property type="protein sequence ID" value="EFQ33594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097614.1">
        <property type="nucleotide sequence ID" value="XM_008099423.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRV6"/>
    <dbReference type="GeneID" id="24413888"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08523"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_5_1"/>
    <dbReference type="OrthoDB" id="6730379at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000064">
        <property type="entry name" value="MFS allantoate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF81">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G01190)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="61"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="324"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="354"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="386"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="417"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="452"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ33594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="512" mass="56406" checksum="8266B49069C8A1C6" modified="2011-01-11" version="1">MADKDIEKTEDGLKPTKSITAGEVELLDESAAFLHEHNISEEYLAELVNDKERNRRLVRKIDLTILPLLAGTYVLQYIDKQALSYAAVFDLFPTTGVTQTQYSWFASIFYLAYLVAEYPWVYVAQKTRMGKVVAGCVLSWGAVLMITAACSSFAGLAACRFFLGAFEAPITTCFMMMVSMWYVRSEQPFRAGLFYCCNGVGSMIGGLLSYGIGQIDGFPVWKAVFLLCGGITVLWGCLLLYLLPDSILGAKRFTLEERALLVGRARLAKTGVLNKTIKLYQVKEAFLDPQVWLLFLFVLLNETINGGFANFGKLIIKGLVTDPLLTTALGIPQGAFQVFWILGGTYTASRFRNMRTIVMAVWLIPTIVGCAMVWKLDRAHYKVGVLIGYYFIGSFVASLVLALHMPASNVGGYTKRITASAIVFTAYCVGNIIGPHAFLAKEAPLYETGCKVILACAAAQMAVAISLRMLLIRRNKARDAAAAATGRAPDAEHDDDDVDLTDLENPNFRYLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSC3</accession>
    <name>E3QSC3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_08894</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697373">
        <property type="protein sequence ID" value="EFQ33750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097770.1">
        <property type="nucleotide sequence ID" value="XM_008099579.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSC3"/>
    <dbReference type="STRING" id="645133.E3QSC3"/>
    <dbReference type="GeneID" id="24414259"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08894"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_8_4_1"/>
    <dbReference type="OrthoDB" id="440553at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1720.10:FF:000009">
        <property type="entry name" value="MFS multidrug transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF51">
        <property type="entry name" value="QUINIDINE RESISTANCE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="168"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="291"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="329"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="384"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="409"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="450"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="474"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="44"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ33750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="515" mass="55980" checksum="58A656CC167F1C95" modified="2011-01-11" version="1">MSRPTSPAPLEKSQTIDEEAAVPPPQPKQPPPYSIYTKWEKRAIVLGACLAAFFSPFTAQIYLPALTVLADEFHVSNSDINLTVTTYMIFQGVIPMFIGSLADHSGRRPAYVICFVVYIAANIGLALSQNYASLLIVRCLQSAGSSSTVALASAVVADTVTSAERGQYVGLTVVPIVLAPALGPVLGGVFTQYLGWRSIFWFLAILAGVYFVLQLLFFPETCRLIVDDGSLRPPRLYRTGYQLLKDHFRARRGTGAPMMRSTTGASSTSKPALKFKLNPFGSLLLLFERELGLLLGFSAIVFAGFYAIATSMPTQFEAIYGFDTLKIGLMYLPLAGGSVVAAFVVGPLINWNYRRHCKRLGIPLDKSRQQDLTDFPIEKVRLEIALPLLFVSSILLLIWGWALHLRAPAAVPCVLLFLFGVGMIGFNNTTNTLIIDIHPGKAGTATAANNLTRCLLGAAASAAIIPMIDGMGVGWAFTFLGLLYVVFSPALFAVMHWGMKWRKAAKAKELKKNTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTG9</accession>
    <name>E3QTG9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09301</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697377">
        <property type="protein sequence ID" value="EFQ34157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098177.1">
        <property type="nucleotide sequence ID" value="XM_008099986.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTG9"/>
    <dbReference type="STRING" id="645133.E3QTG9"/>
    <dbReference type="GeneID" id="24414666"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09301"/>
    <dbReference type="eggNOG" id="ENOG502RHMW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096567_0_0_1"/>
    <dbReference type="OrthoDB" id="5363290at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42083">
        <property type="entry name" value="MARVEL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42083:SF1">
        <property type="entry name" value="MARVEL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="246" mass="26556" checksum="12049761E5703C94" modified="2011-01-11" version="1">MGKLGTALQAGQTAIELGRSAQGLAGAASEFRAADKGEIGRKAGRGVFNEGAETGKTLGKTWLKTFEVIPRLVCRGLQFLFALIACGFYGNRVDADRKGDDGFSPEWILAITVAGASAVTAVLFVAATPLGAIPFIGSKIKIFKTYRAFVWDLILFIAWIVVFGIFAAIFLKRDSEDSYKGSKTGVMKVAVWIDLVNAILWFTSGVYGCIKTFLGDKTDQMTDKIGQKIFEKKQAPVKETGYAESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QU47</accession>
    <name>E3QU47_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_09529</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697379">
        <property type="protein sequence ID" value="EFQ34385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098405.1">
        <property type="nucleotide sequence ID" value="XM_008100214.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QU47"/>
    <dbReference type="GeneID" id="24414894"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09529"/>
    <dbReference type="eggNOG" id="ENOG502T9V5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1111302_0_0_1"/>
    <dbReference type="OrthoDB" id="6133115at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ34385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="281" mass="31676" checksum="B3F0796F3F104719" modified="2011-01-11" version="1">MLGALESEVHLQYMDRLSRSLQSTFDFFHAEIRECRDTLSRLEMEEAKKLVIPEMGIPRTRSMSSAVEPVPFSSAGRSRVNQTRPLRPRKLRKSPPSPPFQYGRSRARRMAADKEPRLWRILGLSLVTWLVVLSLPFTVLATFLCEAAEGVPMYDSNFHSTLSQQLLGFGGLYAIVKPQLEQWLAVLKRSDYGRDPPKGIKTKWPITFNCLVGTAFLTLLASSPIYPYHPQSSIPLGAVAAICANLATLLIIEDTGTQIVVQGEMIEGLEHQLDDYRRRDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUD3</accession>
    <name>E3QUD3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Protein HIR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">GLRG_09615</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 12">Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the WD repeat HIR1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697380">
        <property type="protein sequence ID" value="EFQ34471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098491.1">
        <property type="nucleotide sequence ID" value="XM_008100300.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUD3"/>
    <dbReference type="STRING" id="645133.E3QUD3"/>
    <dbReference type="GeneID" id="24414980"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09615"/>
    <dbReference type="eggNOG" id="KOG0973">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004372_3_1_1"/>
    <dbReference type="OrthoDB" id="1741719at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000417">
        <property type="term" value="C:HIR complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000290">
        <property type="entry name" value="Protein HIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:001557">
        <property type="entry name" value="Protein HIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055410">
        <property type="entry name" value="Beta-prop_CAF1B_HIR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031120">
        <property type="entry name" value="HIR1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011494">
        <property type="entry name" value="HIRA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019015">
        <property type="entry name" value="HIRA_B_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13831">
        <property type="entry name" value="MEMBER OF THE HIR1 FAMILY OF WD-REPEAT PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13831:SF0">
        <property type="entry name" value="PROTEIN HIRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24105">
        <property type="entry name" value="Beta-prop_CAF1B_HIR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07569">
        <property type="entry name" value="Hira"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09453">
        <property type="entry name" value="HIRA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="10 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12" id="KW-0678">Repressor</keyword>
    <keyword evidence="9 12" id="KW-0804">Transcription</keyword>
    <keyword evidence="8 12" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5 11 12" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="CAF1B/HIR1 beta-propeller" evidence="15">
        <location>
            <begin position="27"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="67"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="127"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="169"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="Protein HIRA-like C-terminal" evidence="14">
        <location>
            <begin position="728"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="409"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="568"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="440"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="463"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="507"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU364014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF07569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF24105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EFQ34471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1041" mass="113199" checksum="D49736297B45562D" modified="2011-01-11" version="1">MRVIKPTWLSHSGEQKDFEVYSCHVSSDGKRLATAGGDGHVRVWSTEAIYGDANGDADGKPRQLCHMSHHLGTIHSVRFSPNSRYLASGADDKLICVYHLDKSPPVASFGLGAEPPPIENWKTYKRLVGHENDVQDLAWSYDSSILVSVGLDSKIVVWSGHSFEKLKTITVHSSHVKGITFDPANKFFATASDDRTIKIFRFTPPAPNATQHDMVNNFVLETTISAPFKSSPLTTYFRRCSWSPDGNHIAAPNAVNGPVSSVAIIERTRWDSEINLIGHEGPTEVCMFSPRLFHTENPADNPANNALVTVIASAGQDKTLSIWNTNTSRPVVILQDVASKSISDLAWSPDGTTIFAASLDGSVLGIKFDHGELGWVANADENDKALQKYGASRKGMGIAEDIEGLNLENQSKAGESRAAESRMGALMGDAASSKGPAPATNGTKTVGNGTGTSTPKTLNGNVEPEKDKEKDRPAEENGDKSAERVKELKSRVTVGKDGRKRVAPLLVSSSGTGQSSLPQTQLVGATSTAKAAQNDAPQTILDLERPFEGLPKGGVAAMLLGNKRKLPVVEGEEEEEEDRGSKRLATDPTPIVLNGVDGVEPASVVPASHGVVPTPEYLRPAVLNPSIAFAQIRLAVPKVRSHILRPLERGVLLPESSTDEASKVPENIILEARNPVQIRDPSSISATKRGTLLWQDYLPRAVILVTGNKQFWAAACEDGSIYTWTPAGRRLMNPIIMESQPVILECRNSYLLCINAVGLCHVWDLQKQAALHPPVSLGPVLELATTTLNLNTTTPGPGVTSAQLNSTGHIVVTLTNGDGYYYTRDMFSWQRVSEAWWAVGSQYWNSNDSSISALQSTAVGPVAPAKPKDENTANVSAGIIPYLERHTTNEFLLKGRAYTLQRIVKLLLSKDGFEGFESTVSIAHLENRIAAALHLDARDEFRLYLFMYAKRLGAEGHRGKVEELLNSLLGGILKDKDDRPSDGGRGWFSQEKEICGWDRKELLKGVVMILGKFRELQRLTIQYARVLDLNLESDGAMEMES</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUV5</accession>
    <name>E3QUV5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">LPXTG-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_09787</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697382">
        <property type="protein sequence ID" value="EFQ34643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098663.1">
        <property type="nucleotide sequence ID" value="XM_008100472.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUV5"/>
    <dbReference type="STRING" id="645133.E3QUV5"/>
    <dbReference type="GeneID" id="24415152"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09787"/>
    <dbReference type="eggNOG" id="KOG1289">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004495_6_2_1"/>
    <dbReference type="OrthoDB" id="3257095at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF5">
        <property type="entry name" value="GABA TRANSPORTER (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="255"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="296"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="340"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="389"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="415"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="468"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="501"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="11"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="28"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ34643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="541" mass="59209" checksum="61B520E918949400" modified="2011-01-11" version="1">MGQADVIEMRRPENDYAAVNTTTSSSGKTDDSAGDHYEGRHAQSDGGTGGSSLRRLFSFWQLLAFALIFMSSWEVMAMDMGATFYNGGPQTLAWGIVLVVIGAMAQALSMAELAAIQPIAGAQYHWTHFLAPEKHRRFITWMQGWVTWFAWVSALAGSAASEANIIIGLVSTNYPSYQFQPWHITMVIIAQLVACGLINMYAFRTIPWMELLAGVLHVALWLVFVVVLLTLAPRASADFVFFERTVSSGWTNGFVSWNIGMLVPAWGFIGFDGVVHMAEEVRRAKQAVPRAMLWTIVLNGVLSYGIIMAILFGMGGATEDILASDYPIIPLLFNAAGPKAGTAMVCGLLIITFCVVAASLASVSRITWAWARDGGLPRYFAKVHPKHRVPIRSVWLPCIIVTCLSMFTVGNNATATVFSAFTALSSLGLYSSYIIAISCMLHARVTGRIGHGLEYQVQYGSWSLPKGWGVPINIYALLWSMYLTIWLPFPQTIPVTGTEMNYAGPIYVVAVVGALTLWFARGKKHWAGLNKTAIANVEAYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>E3QV28</accession>
    <name>E3QV28_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">SH3 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_09862</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697383">
        <property type="protein sequence ID" value="EFQ34718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098738.1">
        <property type="nucleotide sequence ID" value="XM_008100547.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QV28"/>
    <dbReference type="STRING" id="645133.E3QV28"/>
    <dbReference type="GeneID" id="24415227"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09862"/>
    <dbReference type="eggNOG" id="KOG4773">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014957_1_0_1"/>
    <dbReference type="OrthoDB" id="548867at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902494">
        <property type="term" value="C:catalytic complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090726">
        <property type="term" value="C:cortical dynamic polarity patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043332">
        <property type="term" value="C:mating projection tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030010">
        <property type="term" value="P:establishment of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902917">
        <property type="term" value="P:positive regulation of mating projection assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032878">
        <property type="term" value="P:regulation of establishment or maintenance of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd05992">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06890">
        <property type="entry name" value="PX_Bem1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11878">
        <property type="entry name" value="SH3_Bem1p_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11879">
        <property type="entry name" value="SH3_Bem1p_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000093">
        <property type="entry name" value="Protein kinase activator Bem1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000184">
        <property type="entry name" value="Protein kinase activator Bem1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000250">
        <property type="entry name" value="Protein kinase activator Bem1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1520.10:FF:000041">
        <property type="entry name" value="Protein kinase activator Bem1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035550">
        <property type="entry name" value="Bem1/Scd2_PX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035548">
        <property type="entry name" value="Bem1/Scd2_SH3_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035549">
        <property type="entry name" value="Bem1/Scd2_SH3_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051228">
        <property type="entry name" value="NADPH_Oxidase/PX-Domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053793">
        <property type="entry name" value="PB1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15706:SF2">
        <property type="entry name" value="SH3 AND PX DOMAIN-CONTAINING PROTEIN 2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15706">
        <property type="entry name" value="SH3 MULTIPLE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00666">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51745">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="33"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="156"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="PX" evidence="6">
        <location>
            <begin position="336"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="PB1" evidence="7">
        <location>
            <begin position="542"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="97"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="275"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="457"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="142"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="278"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="472"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="490"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ34718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="621" mass="68578" checksum="3F3B52587714BD74" modified="2011-01-11" version="1">MPQLLQALRRSIKGEKDNAKINIAPKSAVAIVPPKKVIRALYDYEAQSGQELSFSRGDFFHVIGRENDADWYEACNPALPDARGLVPVAFFQALGRTERDSGQSDGGAIPRPPTMSPTISKNPDHDSGYAEAAPPPGALQSPPLTQRMSRTGSRGGAMVYGIVMYDFVAERADELEAKAGEAIIVIAQSNPEWFVAKPIGRLGGPGLIPVSFVEIRDMATDTAVGDASNAIKKAGIPKVEEWKKMAADYKNSSITLGKFDNGAPPQQGSIEQGMERMSIQQGSRTSSQNGNNYQQQQQQQQQQLQQQQQQQQQQAVYQRTSQQAGGQASPYAKPASQLYAPISARIPRYCFAEDKYWFVIEAVLEDGRHWELSRYYEDFYDFQIALLTEFPDEAGNTGTQKRTLPYMPGPVNYVTDAITEGRLHNLDAYVKNLLAQPAYIARCTLVKQFFAPREGDYEIDPNAPNDEYRLSGGSQPSSTESPADAASRQSSKNNLNGNGYSGLSAAPQQQQRAMGQPGMNRQPSSLSQSQPPPTPGIGQGQAMKIKLYFNGDLIAIRVPTDIQFQQLYDKIVDRLKIADGEEIQLFYKDEPTGDKPNLMSDNDLDYALQRNEKLLLYVEQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QV95</accession>
    <name>E3QV95_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Autophagy-related protein 27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">GLRG_09927</name>
    </gene>
    <organism evidence="23">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasmic vesicle membrane</location>
            <topology evidence="2">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Golgi apparatus membrane</location>
            <topology evidence="4">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Preautophagosomal structure membrane</location>
            <topology evidence="3">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ATG27 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697384">
        <property type="protein sequence ID" value="EFQ34783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098803.1">
        <property type="nucleotide sequence ID" value="XM_008100612.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QV95"/>
    <dbReference type="STRING" id="645133.E3QV95"/>
    <dbReference type="GeneID" id="24415292"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09927"/>
    <dbReference type="eggNOG" id="ENOG502S1VT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047751_0_0_1"/>
    <dbReference type="OrthoDB" id="29460at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030659">
        <property type="term" value="C:cytoplasmic vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.130.10">
        <property type="entry name" value="Mannose-6-phosphate receptor binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018939">
        <property type="entry name" value="Autophagy-rel_prot_27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009011">
        <property type="entry name" value="Man6P_isomerase_rcpt-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044865">
        <property type="entry name" value="MRH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15071:SF13">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15071">
        <property type="entry name" value="MANNOSE-6-PHOSPHATE RECEPTOR FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09451">
        <property type="entry name" value="ATG27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51914">
        <property type="entry name" value="MRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0072">Autophagy</keyword>
    <keyword evidence="17" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="16" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="15 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 20" id="KW-0732">Signal</keyword>
    <keyword evidence="8 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 19" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="20">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180877" description="Autophagy-related protein 27" evidence="20">
        <location>
            <begin position="27"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="267"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="MRH" evidence="21">
        <location>
            <begin position="28"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="114"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="175"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="191"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="EFQ34783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="338" mass="37464" checksum="A85D40AA57FB6A97" modified="2011-01-11" version="1">MHFPRLQRTEAAFLLALLMLPLPVASMLDCKHILVDDVAFNLGALGGPHSVVTSRWHPPTFTNTSYTVDICAPLKRKGDVKKDEQFCAIERTIHPGPDNKDEVEKVIPIAGELGDHGGRALDAKPERLKSSDSHSDAKKEGVRLILNGGSYPLGRSGRNQKAIIEFICDHDKSGLEGEFKPEDQYDGSQFRAREEDKDGKDEDGPSPVEKQLLMPNASLIWNSYGPSEKEDVDVLRLTWYTKYACEDAFGKPPSEGGSGDASSHWGFFTWFFVLSFLGIAAYLVFGSWLNYNRYGARGWDLLPHGDTIRDIPYLVKDWTRSVLNTVNGSGSRGGYSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVK5</accession>
    <name>E3QVK5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_10037</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697385">
        <property type="protein sequence ID" value="EFQ34893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098913.1">
        <property type="nucleotide sequence ID" value="XM_008100722.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVK5"/>
    <dbReference type="STRING" id="645133.E3QVK5"/>
    <dbReference type="GeneID" id="24415402"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10037"/>
    <dbReference type="eggNOG" id="ENOG502S6PS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010595_7_1_1"/>
    <dbReference type="OrthoDB" id="184880at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF10">
        <property type="entry name" value="ABC TRANSMEMBRANE TYPE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ34893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="367" mass="40646" checksum="33EE296B0E4EE698" modified="2011-01-11" version="1">MAEQQAVTKSPTGCPSQSPEAVNQANIPPVAENTVEPAADTTSGQVEATVDALENSEEGDGYETVSDGSSNETASLASSIRDFNFENKRRYHKFKEGRYAFPNDDAEQEREDMKHAMVATLCGGKLHSAPLKNPQKILDIGTGTGIWATDTEIKGIDLSPIQPLYVPAHVSFIVDDAEAEWLQPENSVDYVHVRNMSAAVEDWSRLMSQAYRVLKPGGWIELQEMKWSFNCDDGTMPSTYAVTKMIKLIWEGLGKFGIEADVADTNPQRLKDAGFINQVHDVRKVPVGEWPKREDLKKIGAYFKAVIYDGLYGITVGPLTRGLGWTAEEVEVFLIDVRKDLLQTSIHSYVFYHSVAGQKPEETEVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVX6</accession>
    <name>E3QVX6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_10158</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697387">
        <property type="protein sequence ID" value="EFQ35014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099034.1">
        <property type="nucleotide sequence ID" value="XM_008100843.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVX6"/>
    <dbReference type="GeneID" id="24415523"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10158"/>
    <dbReference type="HOGENOM" id="CLU_2757632_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ35014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="70" mass="7709" checksum="42CBF1D36613C73E" modified="2011-01-11" version="1">MLSYQARITVDMFAVAIDEREASLLHGTLDPVSARIGSKLLSCLLRWATVCHKRTMAYRAGISRWSGVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QW97</accession>
    <name>E3QW97_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10275</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697388">
        <property type="protein sequence ID" value="EFQ35131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099151.1">
        <property type="nucleotide sequence ID" value="XM_008100960.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QW97"/>
    <dbReference type="GeneID" id="24415640"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10275"/>
    <dbReference type="eggNOG" id="ENOG502T60W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2291506_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="101" mass="10966" checksum="E99E61D7CAF8D0D9" modified="2011-01-11" version="1">MSRNSAPLLQQMPLTYSKDHASEQTGPVQTKTGGTEQQAHRPRERVPISAHQNRRCNPASFSTFLLLAPLSLQGSLGHDVRDGSGLVSIGKADASMTWTRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWD6</accession>
    <name>E3QWD6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_10318</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697389">
        <property type="protein sequence ID" value="EFQ35174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099194.1">
        <property type="nucleotide sequence ID" value="XM_008101003.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWD6"/>
    <dbReference type="STRING" id="645133.E3QWD6"/>
    <dbReference type="GeneID" id="24415683"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10318"/>
    <dbReference type="eggNOG" id="ENOG502SHJ6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018354_0_1_1"/>
    <dbReference type="OrthoDB" id="415825at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF9">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="43"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ35174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="499" mass="56333" checksum="0A368A2106C0D1A1" modified="2011-01-11" version="1">MTEAISSKTIEKELGPKLSAGARLQLPGSAGFEKSNLRFTEYERPMYLAAVEPGCDEDVIEVMRYARERGIPFAPRSGHHAVTSTMRYLKNGILIDMRPLNKLSFDADNHQVTVGGGVITDDFVKFLQSVGMEVNVGSCPTTGVIGVAFGAGLGRLQGKYGFLHDNMVSCKLVLADGRVFVASRDSEPDLFWAIRGAGHNFGIALEATFRVYPEANKGIHYTWDLEYTLDQCDPVFDKLNSVHETMPPEMAIFVLWLRQSEGGRKAYISPPFQHHILVNIVWSGKENEAAPWVDRFESLSPVVNSGKVAISWAELPWTTYKGMNKILSKPEVWSLAPNKMMGAACVEKFDLATTKAFLESVKAMNEEWAGKGTFGAMFECLPHHRVRELPSEATAFPWRWGSNHFLMLMATPLKTEHRETFEAHLDRWKKEFIATSGYGRLQQYVNYGNTTSTMRDPPEALYGYEPWRLEKLRALKKQYDPDNVFRWYQPLIEEEIPQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWG8</accession>
    <name>E3QWG8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ZPR1 zinc-finger domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_10350</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Acts as a protein folding chaperone for elongation factor 1-alpha.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ZPR1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697389">
        <property type="protein sequence ID" value="EFQ35206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099226.1">
        <property type="nucleotide sequence ID" value="XM_008101035.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWG8"/>
    <dbReference type="STRING" id="645133.E3QWG8"/>
    <dbReference type="GeneID" id="24415715"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10350"/>
    <dbReference type="eggNOG" id="KOG2703">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024138_5_0_1"/>
    <dbReference type="OrthoDB" id="308464at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.420:FF:000001">
        <property type="entry name" value="Zinc finger protein ZPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.420:FF:000002">
        <property type="entry name" value="Zinc finger protein ZPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.1040:FF:000001">
        <property type="entry name" value="Zinc finger protein ZPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.1040:FF:000003">
        <property type="entry name" value="Zinc finger protein zpr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1040">
        <property type="entry name" value="ZPR1, A/B domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.420">
        <property type="entry name" value="ZPR1, zinc finger domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004457">
        <property type="entry name" value="Znf_ZPR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040141">
        <property type="entry name" value="ZPR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042451">
        <property type="entry name" value="ZPR1_A/B_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056180">
        <property type="entry name" value="ZPR1_jr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042452">
        <property type="entry name" value="ZPR1_Znf1/2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00310">
        <property type="entry name" value="ZPR1_znf"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10876">
        <property type="entry name" value="ZINC FINGER PROTEIN ZPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10876:SF0">
        <property type="entry name" value="ZINC FINGER PROTEIN ZPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22794">
        <property type="entry name" value="jr-ZPR1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03367">
        <property type="entry name" value="Zn_ribbon_ZPR1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00709">
        <property type="entry name" value="Zpr1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Zinc finger ZPR1-type" evidence="9">
        <location>
            <begin position="35"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="Zinc finger ZPR1-type" evidence="9">
        <location>
            <begin position="250"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00054139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ35206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="486" mass="52997" checksum="251E9D172B5BA81A" modified="2011-01-11" version="1">MAVPESKTTPNEFFQAIGSKVDGSDDQKVVEEIESLCMNCGKNGITRLLLTSIPYFREIIIMSFACEECGFANSEVQPAGSIQPKGTYYELRLTAMEDFSRQVVKSDTATVKFTELDLEVPAGKGQLTNVEGLLTTVINDLEFGQEARKEQMPEIYPKIAEIIEKGRAMLEGKSFPFRVTVDDPAGNSFITPDLKDGVGKWEKHEFIRTAEQNAALGISNEQAAELAAGANPGLTAEGDIIPNEVYSFPASCPGCMRPCTTHMKMVDIPHFKQVVLMSTVCDECGYRSNDVKTGGEIPEKGEKIIVKVNGQTDLARDILKSETCALECPELNLAVNPGTLGGRFTTIEGLLTQVRDDLRSQIFEADGGSGGSGGGDSLAPEEKSKWTAFFDGLDEAINGNREFTIVLNDPLASSFVQPLVDPPAPDPSITREYYTRTHEEEEELGLLDMKTEGYEEDAAKEAAERDQAKKLAELDKLLDANMGNTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWM1</accession>
    <name>E3QWM1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">CBF/Mak21 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_10403</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CBF/MAK21 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697390">
        <property type="protein sequence ID" value="EFQ35259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099279.1">
        <property type="nucleotide sequence ID" value="XM_008101088.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWM1"/>
    <dbReference type="STRING" id="645133.E3QWM1"/>
    <dbReference type="GeneID" id="24415768"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10403"/>
    <dbReference type="eggNOG" id="KOG2154">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015945_1_0_1"/>
    <dbReference type="OrthoDB" id="10263185at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030692">
        <property type="term" value="C:Noc4p-Nop14p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000480">
        <property type="term" value="P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000472">
        <property type="term" value="P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005612">
        <property type="entry name" value="CCAAT-binding_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027193">
        <property type="entry name" value="Noc4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12455">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12455:SF0">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03914">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="CCAAT-binding factor" evidence="6">
        <location>
            <begin position="317"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="11"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ35259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="544" mass="62305" checksum="818A89329ED76A0D" modified="2011-01-11" version="1">MPARVSGEGLKRKRVSPKEKSKKRSKSESESEAESNESNDPQAEILLLENDIFESKKHYNNISKLIKTTNTHEDEPEVATLACVALCRVFVRLLSAGALVPRKGLPEKEAIVTHWLKERYFEYKDVLISLLSKEDLASTALTLAMRCLKVEAQHLYEKEDYIFPHNFLEQIIAGLLQSDSDDTRVEFVEKYLTQYDDIRFSTLKAIKSLAETPGSLPEDELFDDAFELLTNIGDVPTELGNFFAEKPKKKSHNINSLHQHKKQGQDAWLAVLKLAATREQRKKVLDVMSNEIAPWFIRPELLADFLTDSYDAGGSISLLALSGVFYLIKERNLDYPSFYTKLYSLLDSEILHSKHRSRFFRLMDTFLSSTHLPAVLVASFIKRLARLSLNAPPSAIVFVVPWMYNILKRHPLCTFMIHRETRGPEAKMLMEKQGLDDPFVADEADPMETHAIDSCLWEIVQLQSHYHPNVATIAKIMSEQFTKQSYNIEDFLDHSYGSLLEAEMSKQVKKQPVIEFQIPKRVFLPNEPDSGFQDNLVTKLWSFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWY4</accession>
    <name>E3QWY4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Amidohydrolase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_10516</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697392">
        <property type="protein sequence ID" value="EFQ35372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099392.1">
        <property type="nucleotide sequence ID" value="XM_008101201.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWY4"/>
    <dbReference type="STRING" id="645133.E3QWY4"/>
    <dbReference type="GeneID" id="24415881"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10516"/>
    <dbReference type="HOGENOM" id="CLU_2849569_0_0_1"/>
    <dbReference type="OrthoDB" id="432010at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ35372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="65" mass="7380" checksum="207896826EF396C4" modified="2011-01-11" version="1">MACLLRETRAERVVFSVDYPFSGNREGRDFMHELRGSGLVSEAEWEGIAWRDAKGLLKLNVEPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXE6</accession>
    <name>E3QXE6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Na,H/K antiporter P-type ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_10678</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697395">
        <property type="protein sequence ID" value="EFQ35534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099554.1">
        <property type="nucleotide sequence ID" value="XM_008101363.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXE6"/>
    <dbReference type="STRING" id="645133.E3QXE6"/>
    <dbReference type="GeneID" id="24416043"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10678"/>
    <dbReference type="eggNOG" id="KOG0203">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002360_4_1_1"/>
    <dbReference type="OrthoDB" id="158672at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005391">
        <property type="term" value="F:P-type sodium:potassium-exchanging transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030007">
        <property type="term" value="P:intracellular potassium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006883">
        <property type="term" value="P:intracellular sodium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990573">
        <property type="term" value="P:potassium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036376">
        <property type="term" value="P:sodium ion export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000114">
        <property type="entry name" value="H /K ATPase alpha subunit, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000083">
        <property type="entry name" value="Sodium/potassium-transporting ATPase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050510">
        <property type="entry name" value="Cation_transp_ATPase_P-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294:SF21">
        <property type="entry name" value="CATION TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294">
        <property type="entry name" value="SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00121">
        <property type="entry name" value="NAKATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="342"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="380"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="892"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="993"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1034"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1065"/>
            <end position="1083"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="11">
        <location>
            <begin position="99"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ35534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1104" mass="121931" checksum="380FA2FEAD196ACD" modified="2011-01-11" version="1">MDEPEKSHSQAAGERIRWDADEEAGRRAHRSSTVPGLQLTRSNTSMSIHSVRSRRNSIDATAELPIQYRTVSFEIEEYKSKTEAVKKAKNVATELSELEWHTLAVNEILRRQSSSLADGLSSDQVQRRMAHYGRNAPSPAPTNHTKRILGYFFKGFGTILLVASILVFIAWKPLGSPPAVANLALAIVLLAVFFIQAAFNMWQDWSSSRVMNSIKTMLPENCMVIRDGQQAELPADQIVPGDILIVKSGNKLPADVRFLKVSSDAKFDRSILTGESVPLPASVDSTDNNYLETRCIGLQGTHCVSGTCTGLVVATGDNTIFGRIAKLTNEPKKGLTTLEREVLHFVLIICSIMFLMIVVVLIVWGAWLKQKYPNWINVPNLIISCVSVAVAFIPEGLPVALTASMTISANMMRKNKILCKSLKTVETLGSVSIICSDKTGTLTQNKMVVTECAIGTKTMTADGARDELTLSRNNTPNNNSLEQLRAIAGLCNAGQFDAATIRLPLHERVIHGDATDQAILRFSESLGQVNELRRCWQTKYELAFNSKNKYMIRVLGMSHPDGLSLALPSDTASVFQPGDVLLTIKGAPDVLMPRLSNYVNPSGYTTALDPSTRASIERIKDEWSAQGRRVLLLARKAISKSALKGSPTESSYEMEVNNQAKSGLTLVGLVGIVDPPRPEIPEVMNTLRGAGIRIFMVTGDFALTASAIAAECNIISVPRSQIDDVTALQRMTPVEPSVKQVIDDVQSSPRQAIVLSGPELITLNEEQWDQLAQYQEIVFARTTPEQKLRIVRELQARHQIVGMTGDGVNDAPSLRAADVGIALGSGSDIAIEAADMVLLDSFSSVVEALRYGRMMFDNLKKTVAYLLPAGSFSEFWPVMTNVLFGIPQILSSFLMIIICLFTDAAAAIAMAYEAPEADVLLRKPRVPGKDRLVDWQLVVQSYGLVGMLETISSFAMSYWYLERQGIKFSDIWFSFGNLPPSIDPNFYQQQLNIASSIYFVNLVVMQWFNLLAIRTRRLSLFQHPPIGNKQTQNLYLFPAVVFALLMAIFWLYVPEFQSTLGTSPVPVEYWFLPMSFGLGIVLIDEARKFAVRRWPTGMFAKAAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXQ7</accession>
    <name>E3QXQ7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_10804</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697397">
        <property type="protein sequence ID" value="EFQ35660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099680.1">
        <property type="nucleotide sequence ID" value="XM_008101489.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXQ7"/>
    <dbReference type="GeneID" id="24416169"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10804"/>
    <dbReference type="eggNOG" id="ENOG502R0P1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104266_0_0_1"/>
    <dbReference type="OrthoDB" id="4589291at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ35660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="210" mass="24931" checksum="4612DEB376E5C2EE" modified="2011-01-11" version="1">MVTTRHVSKQVPTARRSHLQNFDSQKWQDTEVQVLFIFNSPDGENTEDEDIKWEAFLQVKVRNLPRLMAEGFYWNEANLEREAGYIERRLLKDDPFNDDDRWSCCRTFFLSDLSDDPQWAAKLIVYAEKLTVLSSFTITNINMDTMDGAVACNKVADERSATRWVYFWDRNYPEDNFNAIYDDMPLEGWWPWPREEFDDDDITLVNVEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>E3QY25</accession>
    <name>E3QY25_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_10918</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697399">
        <property type="protein sequence ID" value="EFQ35763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099783.1">
        <property type="nucleotide sequence ID" value="XM_008101592.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QY25"/>
    <dbReference type="GeneID" id="24416283"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10918"/>
    <dbReference type="HOGENOM" id="CLU_1499753_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ35763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="180" mass="20048" checksum="183B38F47547BA60" modified="2011-01-11" version="1" fragment="single">MFISSVIVFAANGISSDLTLSHATIPSDRFDTVLRKPHSTMKASSFRESLGGTWRNRKPHLVTCIRRARRHKSVRVPRPMPRTKPRCSTYQFAPRDPLLGPDTAHLSSAQCLVSRSLSLSVSLSLPLSLPLCVCVYVCVCVCMRACMYTPAPPKFSHPPKKIEIARPNLEKFKNKKDAGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QY49</accession>
    <name>E3QY49_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Peptide hydrolase</fullName>
            <ecNumber evidence="14">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">GLRG_10982</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Extracellular aminopeptidase that allows assimilation of proteinaceous substrates.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the peptidase M28 family. M28E subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="14"/>
    <dbReference type="EMBL" id="GG697400">
        <property type="protein sequence ID" value="EFQ35787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099807.1">
        <property type="nucleotide sequence ID" value="XM_008101616.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QY49"/>
    <dbReference type="STRING" id="645133.E3QY49"/>
    <dbReference type="GeneID" id="24416347"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10982"/>
    <dbReference type="eggNOG" id="KOG2195">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025866_1_0_1"/>
    <dbReference type="OrthoDB" id="2214at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03879">
        <property type="entry name" value="M28_AAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF56">
        <property type="entry name" value="AMINOPEPTIDASE YDR415C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 14" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0732">Signal</keyword>
    <keyword evidence="8 14" id="KW-0862">Zinc</keyword>
    <keyword evidence="9" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005127948" description="Peptide hydrolase" evidence="14">
        <location>
            <begin position="25"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="15">
        <location>
            <begin position="213"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00043843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00043962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EFQ35787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="442" mass="48697" checksum="1EDD6F95205C3350" modified="2011-01-11" version="1">MAAMRYALSTKLLLLLGSSQLVLGFPGDQVVIAQTPEEHAAAAVPGTVWAVDSSIHAALEKHSDPVDALVSLQPEMAAKMAEARLMHVFGEKKAEWMTEGDKLRLRRKGRKFRDMTDFQELYDSVDTQSGKANLPEIAHQRLVRPLFSKVNQTEMHDVLEHMTSYYNRYYGGPTGEESSVWLHDHIAGIIAESPLHAHISLEYFTHEFPQSSIIARFEPKVRDFSKPLTIIGAHQDSANYLFPLLPAPGADDDCSGTVSILEAFRVLATSGYVPKEGPVEFHWYAAEEGGLLGSQAVAAYKKKEGANIGAMLEFDMTAFVARNATESIGFIKTDADAPLTKWAVALGEEYVNITTSVYELMPGAGSDYMSYTKLGFPAAFASEGNPVAGGFPGEFDPYVHTDKDTMWVDDETGVFSIDHMARFSELAIAFAVEQSGWDNKWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYJ8</accession>
    <name>E3QYJ8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11044</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697403">
        <property type="protein sequence ID" value="EFQ35936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099956.1">
        <property type="nucleotide sequence ID" value="XM_008101765.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYJ8"/>
    <dbReference type="STRING" id="645133.E3QYJ8"/>
    <dbReference type="GeneID" id="24416409"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11044"/>
    <dbReference type="eggNOG" id="ENOG502SPSM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_580026_0_0_1"/>
    <dbReference type="OrthoDB" id="5213630at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="471" mass="53626" checksum="518A0B4BCAC1B82D" modified="2011-01-11" version="1">MQQTSGERQETRTDSSLNKNSLEPQFRQHYQHHCDLRSDLRGQDILHLDTIMDDTAFNLMPETQVGEPSVIDGSSDDQKNRAQDATYFMPHAAEVRSLQDQVIQLHMQFEDYETDISKLETDIAHVENGFVHIETDIACVRTEIACVAKMVEDAERQRTEMQQSYQRDVSKHVAHINKLDGKIRHLKAQVASLKAVKSQDKAIANSRKVSDDVIKASWRTMTYNIRSLVATILTGHSSRHDLDHHGHEDKEESCAFCQLDARQILLLQNDDIRESVVEKLVWDAVVSRIFSPNGVRFGRNWAGTPGQLLSALFNQLLEVPEMSNNPTMLFRWKAESAVMMDKVIGFNNKELNSIVDKEYRGLCAFIPHDCPNITVARKSLHQELRNIFKEATEIHRILMQSRAYFYIDPVIAEDTVHYNPEYHEAEVYETELSSKSTVLLGISPSLVKCGNADGGNYDKSNRLVKASVICD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZ43</accession>
    <name>E3QZ43_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_11275</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697410">
        <property type="protein sequence ID" value="EFQ36131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100151.1">
        <property type="nucleotide sequence ID" value="XM_008101960.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZ43"/>
    <dbReference type="STRING" id="645133.E3QZ43"/>
    <dbReference type="GeneID" id="24416640"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11275"/>
    <dbReference type="eggNOG" id="ENOG502RP5V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_903396_0_0_1"/>
    <dbReference type="OrthoDB" id="4851849at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ36131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="291" mass="33582" checksum="859D02CAA0EBBB99" modified="2011-01-11" version="1">MIRTTLTKMPLLWTIDDETKFHQAIAQISKLRQTPLQEANYRHQYRGGSQSSDHVLRLEDEMQLADHVAFIAHSSEGFPEIAAACIEERPDQQGLLIRLARNELRRTEEVESVRCLLRVLEGCASGVLHRSAVQDRLFNEVLAISENRILQRLMPPWYPAPSHWNAKQRQQRTSLHHRMTTLLLPKLRGSKFETIYLNFIRATKALEPLESKQIGPDLRKHVKIAMQCCANASIGTDQKSLELQLKHILNQLSKAARKVVVQVDKIARYLNLSRDLAKMVMRKAYRNILER</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZB8</accession>
    <name>E3QZB8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Zinc knuckle</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_11351</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697414">
        <property type="protein sequence ID" value="EFQ36206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100226.1">
        <property type="nucleotide sequence ID" value="XM_008102035.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZB8"/>
    <dbReference type="STRING" id="645133.E3QZB8"/>
    <dbReference type="GeneID" id="24416715"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11351"/>
    <dbReference type="eggNOG" id="ENOG502SDVN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_366377_0_0_1"/>
    <dbReference type="OrthoDB" id="3550095at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="17"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="34"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="387"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="451"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="86"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="162"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="198"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="232"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="264"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="293"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="317"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="463"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="488"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="555"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="585"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="649"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="693"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="716"/>
            <end position="726"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ36206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="734" mass="80007" checksum="29E185AF86D2747C" modified="2011-01-11" version="1">MADHAPGSGPATKEPSCINCGGVGHWAVACPEPVRAKPAGLPRRNTSSSRDHGRGSNHQHGGRRPGAVVTKYPAPPTGSQIVTRYGPPPGQPHAPPVPRPPQPYPSYPPSPAGYVPPPPSSYPGYPPYSPPPPPGAYPPPPGPPGPSAPYHYPSPGQYGGPPTGPTGPPPPSYQPPLPYPPSASYPPSYTPPSEYQPVPAPPPPPLPPSGQYSAPYNPITYGGYSPSTYGLPPAPPPYRPQPGPPQPPPSYAQPYGPPASGVGPLPPLPTPPRGSPPGLPPIPPHRNQLSRDRHGRHRQGHNHRPDRSRKNNKHSNPKRDAPQPRQKSDGNKEEQEPAQVVPEPKQPKTASVPNVTTPEGRHDNSVSEEGVDDDEVDWMWEAEMIFKETDNAHQPDPIAKPLPGPEDYHDNIMLPPAWNATCMLSEFVTDKNLEEFSRPIRETKHFASLQLDPVFWRGPVESKTARQESEPRDSKPVSFKSTRLPGFPSLPPKPPTPENREYRLVNSRKRTWEETPNKTSRTRSSQDGDWASHRQKRHRGDSHSGHDTTSPHSRTTREDSRPIDRYRFQRLDRDESDPTDALLKSLDDSHDAGPSRRHGGDEKFTTRHDFDHNSSQDARRQGSASGFHEGRTPPLLGTPPPEDSAQRRQASRSRSRSRHSHRPGSGSSHAESRPASRQSAASFASHGTEDSELSALEAELLGIAPKPKGGKESKHGGHGLKFRKRVPKVDSAYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZP6</accession>
    <name>E3QZP6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PIPK domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_11479</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697419">
        <property type="protein sequence ID" value="EFQ36334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100354.1">
        <property type="nucleotide sequence ID" value="XM_008102163.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZP6"/>
    <dbReference type="STRING" id="645133.E3QZP6"/>
    <dbReference type="GeneID" id="24416843"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11479"/>
    <dbReference type="eggNOG" id="ENOG502SIZC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052383_0_0_1"/>
    <dbReference type="OrthoDB" id="70770at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016308">
        <property type="term" value="F:1-phosphatidylinositol-4-phosphate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.810.10">
        <property type="entry name" value="2-Layer Sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.800.10">
        <property type="entry name" value="Phosphatidylinositol Phosphate Kinase II Beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027483">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002498">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027484">
        <property type="entry name" value="PInositol-4-P-5-kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023610">
        <property type="entry name" value="PInositol-4/5-P-5/4-kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086:SF126">
        <property type="entry name" value="PIPK DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01504">
        <property type="entry name" value="PIP5K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00330">
        <property type="entry name" value="PIPKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51455">
        <property type="entry name" value="PIPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PIPK" evidence="2">
        <location>
            <begin position="1"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ36334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="361" mass="41187" checksum="DEA58E674B64D7E5" modified="2011-01-11" version="1">MQIRSSSISSSILAAISADSSNPDRPSLQKRIFRLLATFLSVFHLPLARYRASDFLELRHNVWQLDEHEYANSFHLSQKAAKGKGRESDLKPVGDLGYSGSTFFTTADGKFLIKSLPRRFEHEFFTHDLFGAYVSHMKKNPHSLLVRITDMVYTSIATLGGILGTAPTHHIIMENLLYGKAEEETDHRKKQWETYDLKPNDYFFPERDIANGRLAPESVKERLIDEFDDKIRVTAAQKEELLGLLGADTQLLADNNAVDYSLFLVRYPGPNVLDEPRDIPTIKSNANEWRTGLTDVDGNWTYRMIVLDFFWAKHKFRAKAMTGLVKSYNVIAGHGPMSITANPIEYRERFLNMVRDLIIEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZT0</accession>
    <name>E3QZT0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aflatoxin regulatory protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11513</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697420">
        <property type="protein sequence ID" value="EFQ36368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100388.1">
        <property type="nucleotide sequence ID" value="XM_008102197.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZT0"/>
    <dbReference type="GeneID" id="24416877"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11513"/>
    <dbReference type="eggNOG" id="ENOG502T4U1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038954_0_0_1"/>
    <dbReference type="OrthoDB" id="4222821at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="372" mass="39532" checksum="98ED8C2BB8067EB4" modified="2011-01-11" version="1">MQQSHVSRGSGGPGASSSGPATSTERGRTTTAGEDYSEFWTSCSNDMLPSWGWNGEDLSGLISTNKDTPSLSSAGGVASLDDELAGATVTQTSPPDIEIHPPQGDHRRDLYRQLADLSHTLSQDAQGLASSSLGADLDLKHVGSSCIQRAFKCLEALKSLTDELRIKTQHSLQALPQADVLLTPNSDWSRTGVFFTEKDADHLGRSCQTGPGTTTTADVRPGTDRHLDMIMSLHIVTSYVCLNQILKRTLGSILAAVVSQQKGGGDGSGSSSTEKPLLLWPDIQIEGLTGDGDNLLRVRLFAETCLHVATGIHKRLESLTSAAKDTMGSSLSRPMMMVLGGGGDSLDELDVDIRGIKLLCSQISSAVEERAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZT8</accession>
    <name>E3QZT8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">L-galactose dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_11521</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697421">
        <property type="protein sequence ID" value="EFQ36376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100396.1">
        <property type="nucleotide sequence ID" value="XM_008102205.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZT8"/>
    <dbReference type="STRING" id="645133.E3QZT8"/>
    <dbReference type="GeneID" id="24416885"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11521"/>
    <dbReference type="eggNOG" id="KOG1576">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_7_0_1"/>
    <dbReference type="OrthoDB" id="5286008at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045290">
        <property type="term" value="F:D-arabinose 1-dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070485">
        <property type="term" value="P:dehydro-D-arabinono-1,4-lactone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42686">
        <property type="entry name" value="GH17980P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42686:SF1">
        <property type="entry name" value="GH17980P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="22"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ36376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="404" mass="43632" checksum="B794C9C55F9441FA" modified="2011-01-11" version="1">MAAPRTNASAADRVPLSAVLPPLVLGTATFNYQYVSDPDRMPSFDIVSRALDLGVRAFDTSPYYGPSEAILGSALRALSPPRESYFLVTKAGRIAPAEFDYSPAWIRASVRRSLERLNTSHLDLVYTHDAEYVSPDDVVAAVRELRLLRDEEALVRYVGICGYPVPVLCELAEKVLRETGEPVDAVQSFSHFCIQNNTLGSDAVLSRLRAAGVSVVTNASMLSMGLLTTRGVDDGPMASWHPAPSPLRKSCKGLAGIAEGVGEKMEEVALYWAMANWARVGAAFGSEVLSPAYNSPAKVGVSVMGVTSVSELEETVAAWQSMLRELAAESSTDKTPTDASLLSRYNKIERLVTEHMWPALGEWRNYSWASPDENFVNQRTQTSDAAAVVDAATSTLAAAAESHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0L2</accession>
    <name>E3R0L2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">GH18 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_11796</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the glycosyl hydrolase 18 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697455">
        <property type="protein sequence ID" value="EFQ36650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100670.1">
        <property type="nucleotide sequence ID" value="XM_008102479.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0L2"/>
    <dbReference type="STRING" id="645133.E3R0L2"/>
    <dbReference type="GeneID" id="24417159"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11796"/>
    <dbReference type="eggNOG" id="KOG2806">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1348822_0_0_1"/>
    <dbReference type="OrthoDB" id="73875at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053214">
        <property type="entry name" value="LysM12-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47700:SF2">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47700">
        <property type="entry name" value="V CHITINASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G13720)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="4" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="9 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="7" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="GH18" evidence="13">
        <location>
            <begin position="56"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ36650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="203" mass="22317" checksum="7E3E3110C5BD46A8" modified="2011-01-11" version="1">MGLHLYGAGARTEKWVLDAANATDCNPGTKLPGFQSTCISNCGNEIKQSSGPPVSFSRVGYYESWNMNRDCLWLLAEKSNTDGTYTHMHWGFADTNTWKPVIADPHGQWEGFKKLQLKRIVPFGGWAYSTEPATYNIIRCVIIGNREAFTKNHAQFAKDKGIDGIDIDWEYPGAPDIMVDGQPIGQAGDGQTSCCTRATTSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0R4</accession>
    <name>E3R0R4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_11851</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697478">
        <property type="protein sequence ID" value="EFQ36702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100722.1">
        <property type="nucleotide sequence ID" value="XM_008102531.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0R4"/>
    <dbReference type="GeneID" id="24417214"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11851"/>
    <dbReference type="HOGENOM" id="CLU_1224681_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ36702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="226" mass="24884" checksum="8014F8588237AC95" modified="2011-01-11" version="1">MSVMPMRASRYVSYHGHAKSRVRRYATPHEVGPAAKCLGAHVLFVRHDKDPAARVQAGEHGPALQRLWVAGVSRRLRGRRRRDVAVFSVGIGVTAAPGNRSSAVETGAVPEETRDETLRPQEAIAQEEVEGQEPGRVADLLAHRAHEVRELPADEHVLYGGCLDQVFGSQPVTARVNEPGLPAERCREGPRELDVFAWQELRREGGRADFGKNPRGELVVGSARMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0S2</accession>
    <name>E3R0S2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_11860</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697480">
        <property type="protein sequence ID" value="EFQ36710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100730.1">
        <property type="nucleotide sequence ID" value="XM_008102539.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0S2"/>
    <dbReference type="STRING" id="645133.E3R0S2"/>
    <dbReference type="GeneID" id="24417223"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11860"/>
    <dbReference type="eggNOG" id="KOG2614">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_19_0_1"/>
    <dbReference type="OrthoDB" id="9993796at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF215">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="2"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ36710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="394" mass="43171" checksum="242CC92E01F15495" modified="2011-01-11" version="1">MQVIIAGSGVAGLSAAISLRRCGHSVTIYERSSLNHEFGAAINVPPNVARFLVAWGLDVVEAQFVPSESMYIFSPTQRDKVLAYSDFRHNINKYGAHLYYAHRVDLHSNLKRMATAPDGPGTPVTIKTKSEVMAYDPETPSMTLTDGTILTGDLLIGADGIHSISVAAILGHPNPPKPAQHSNCCYRFLIPRALVEDDPETSFFTKGLVGLQGLRIWPDVAGNRRLVYYPCRNTQVLNFTIMCRNDELGSGKEDWNTPATKEEVLKALEGFDPGLLSVVGKCPEFKRWPLQYRPPIPTWHKGNMAIVGDAAHPMLPHLGQGGAQGLEDGLAIGLVMSGATKAEVPERLAVYQKIRHNRASAIQIMSNYGFDQKPPGEVLNYLEGQALPSKYSHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0Z7</accession>
    <name>E3R0Z7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_11932</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
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            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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    <dbReference type="GeneID" id="24417295"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11932"/>
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        <location>
            <position position="504"/>
        </location>
    </feature>
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        <source>
            <dbReference type="EMBL" id="EFQ36785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="504" mass="56781" checksum="106D53A9357E27B4" modified="2011-01-11" version="1" fragment="single">MTFCITQRCGLCRFRLHDGERIVAGESSHPLVIAPLIPTKVEDAGQISDDMVYEDNAVDQRGSSYMKCLGDCSHWEGRTTGCHVECANQVSPWPVSEAVKVLAFNYTPTPSECDIREAWLRQTFVAFLNGTFRRLPPELCSKIAANLCIRTYAVACAKALRAVRGGEFSLCLSSKIWGRFTEFEGSSYLSSLSNNGDDYHNHLIFEPDPTSALGRFVYLAEDYFGVRKMFFSYPTPDVEELRGLWWRVVDLERSPTLAARSRCLKLRWFVSKGPNSNQHRWANVLWAVPPSTAPRLIKLEVSPEVERMSVVSCNDPSVVAYSVHWNTRIMSIHTHTREKELSMYHNRANGIWLFFPLYDHENIAEIWIRGTTKQEIALILTTTRGRSLVFGPHLDILPTTRLALIDLPSQDSSSRIFVEESSVGIRNVAFESSNPEPALSPSVSLPQPTYRAPVSNPQTPWFYSTASLDDVEDVRPCQRSIGGRNIIIGLLLRYVDGHEACLGQ</sequence>
</entry>
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            <taxon>Glomerellaceae</taxon>
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            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
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        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EFQ25133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089153.1">
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q232"/>
    <dbReference type="GeneID" id="24405642"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00277"/>
    <dbReference type="eggNOG" id="ENOG502T3RU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2440699_0_0_1"/>
    <dbReference type="OrthoDB" id="4845523at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ25133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="91" mass="9905" checksum="EBBF2EE427F750A6" modified="2011-01-11" version="1">MAKRKTAPAASSSKAGGDDTAPATQQPQQQAGNDRPTTQLGRAAAFLMPPAWMRRIMFVAVLIYLTPMLLAHWIETSTKLIGLFRSFTSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2B2</accession>
    <name>E3Q2B2_COLGM</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
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    </protein>
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        <name evidence="3" type="ORF">GLRG_00357</name>
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    <organism evidence="4">
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        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="GeneID" id="24405722"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00357"/>
    <dbReference type="eggNOG" id="ENOG502RIUN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116368_0_0_1"/>
    <dbReference type="OrthoDB" id="5227396at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
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    <proteinExistence type="predicted"/>
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            <end position="76"/>
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    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ25213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="224" mass="24266" checksum="B6B488ECBC9CCBA7" modified="2011-01-11" version="1">MVSCFNDETRARGTPKGFYAAPPPPSSAPQPAPYNTAARSGPPGKADILARQLAALPLIALLYTAAVPFTPAAWVLHVGGSSLFDRLFAGIVVLAACYFQWRVAGLTAPLAVFFPGVGGGGSTVRNGRIERAPGPGFVWHPDHYWPYAICEAVLLCVAEFGGNELLRRYIICGVLGGLWLVGYHATPESTRRWAYENIKGWLFGMVLDGMMRVGGRSYNARRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2S1</accession>
    <name>E3Q2S1_COLGM</name>
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        <submittedName>
            <fullName evidence="8">PH domain-containing protein</fullName>
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    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_00044</name>
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    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
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                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ24900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008088920.1">
        <property type="nucleotide sequence ID" value="XM_008090729.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3Q2S1"/>
    <dbReference type="GeneID" id="24405409"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00044"/>
    <dbReference type="eggNOG" id="ENOG502QU87">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001720_0_0_1"/>
    <dbReference type="OrthoDB" id="10070851at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd07609">
        <property type="entry name" value="BAR_SIP3_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13280">
        <property type="entry name" value="PH_SIP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000079">
        <property type="entry name" value="Transcription factor SipA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039463">
        <property type="entry name" value="Sip3/Lam1_BAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042067">
        <property type="entry name" value="Sip3_PH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031968">
        <property type="entry name" value="VASt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14248">
        <property type="entry name" value="CYCLIN Y, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16746">
        <property type="entry name" value="BAR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16016">
        <property type="entry name" value="VASt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51778">
        <property type="entry name" value="VAST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="PH" evidence="6">
        <location>
            <begin position="312"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="VASt" evidence="7">
        <location>
            <begin position="932"/>
            <end position="1103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="417"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="459"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="558"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="869"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="567"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="870"/>
            <end position="884"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ24900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1401" mass="155312" checksum="427E345535DDC12B" modified="2011-01-11" version="1">MTEPAPAAAPGAATTPAQKQTSPAIPVGLNEASLDSPTFRATAQYFGEHIDNVEKWLDDYVRSASRVTRDILALEESVNAYLSKIFPPAAIADSIVDHDYTLLALRRISDGSKEWWTQIMSAVRKMDTISVEPIRSFVAADLRSFKEVRRVLEHTQRNFDQAMARYMSQSKTKEPSAIREEAFAVYETRKAYLKVSMDFCQLAPQIRFSLDKLLVRVSSDFWKEMKRSRDAAAASTKWGSEMDRIRGWSREMETTEFVFKRELQIARRDIGESTLQDFKPSRELEDYSASTVPFLGSRGPVSVQPQENSAVVSEKQGWLFLKTLYGKPARSNWVRRWYYCRDGIFGWLINSPQGVLQGDEVGVLLCNAKPAVAEDRRFCFEVKTKSQTLVLQAETQTQLTEWLEVFEVAKKRAFETSMDRDSTSSPAGADPAFSITPPPLPEFSARSLDAVVAGEEPAATFERAGTLPVPSADGNAGGRASFDVNGVPRRSITALGRDLGREMVREEGESNRDHAARIIQKLDLHRKATFGAGAEAAVAAAATPGSGGIASLLASHGHLPGYPSPPQGGSKNSSVSRLPALDPVQGTLAPLTLAKPPAATNLSRTAVMFSVDRSVGGDNTSHMPTAVLANYWGSSAWSVVYGSGPGRPRTPGLLEENPFGIVVREVGKPGEEKPLATSAGGHRKTVSVDAKINQPHVPFKQPAETFPPGYPPELRIQHHQFRILFPTVPLDEKLVLVFRAAWSSSAGKDSPSHGQGLAGNGRIYITPDNMYFYGQQMGLVVAYAISLDIIAEVTAAPGKECDFIFLHLGEDGNDTGYTRITIKIFLDNLKLLHARLNLLIDDLQSEEPLELSELIRALINQEYEDHNKRSPSVESWEEISSNTPFDDGTHSGRPARRQSQFGPRLRLSGPGSRQTPKVQLPAHPVIYEPEDMQRMVAERHFEISAKACFHVLFGDKSFVFPKLYFERRAQQIAQGPWELADHGRMKREFHFKFDYKDMLGRHKTVDVVDSQTMDIFQEHVTYVVTHTKTAWHLPHSQDFKLVTKVVITHVAKSKCKLAIYTKIEWSKVPTFSKNLVERQALNDAEGDAEELADVATDQVRKLGPHSRTKRAIQVYGNIGQQTQVVVFSPADAAASKKQLIKPRTLTAMLLETLRSFGESAVTSLIMWAIAGVKTIFSVVTAHRLILLVLAVSAFTNIALTSKGSSTWWMERKAAKFMSRVGVGPNVMMSKAIYMADLNEATGAVGHNNSWPTDSACFTTFQLVANATDLDAPYEDAGSTLASATGRATARRLRRTRQRLGSYRHDLIVAMRIVNSIEREMMQSEWENWLADENMRCDKLKMVLEEGGAGAKTKRSGSQKVMTAAMDEGKKETLREWYDTYCGSCKLDHRALMSERNSLASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3J2</accession>
    <name>E3Q3J2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_00738</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the amidase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089614.1">
        <property type="nucleotide sequence ID" value="XM_008091423.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3J2"/>
    <dbReference type="STRING" id="645133.E3Q3J2"/>
    <dbReference type="GeneID" id="24406103"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00738"/>
    <dbReference type="eggNOG" id="KOG1211">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009600_0_2_1"/>
    <dbReference type="OrthoDB" id="421993at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895:SF67">
        <property type="entry name" value="AMIDASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="TRANSAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="3">
        <location>
            <begin position="166"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ25594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="611" mass="66393" checksum="BF71944B2B22EF2B" modified="2011-01-11" version="1">MAPNQKYANYPGAREAPAQNNSGTPKEDQNPVLRGWPLVVGSALVANSGAVQRFFWRNAKFGSIRDLPGLVDYRYRFQPDVLVLSESGTHPDPFPLTPELTTPAPQDQPSRYLSSADYHALYASGAATPLDVVQSLLPLVRRAEGHPPPETGPYANAWVASHGREDLAIDAARASTERWRRGEPLGPLDGVPIGVKDDIDVKGYVSHNGMQYRPDLPWFKPAEETMWPVRQLEAAGAIVLGKNAMHELGGDTNGCNPRWGTPTNWHNKSYYPGGSSSGGGSALGAGIVPISIGTDAGGSIRIPASFNSAYGLKPSHHRACTMNTSVCVVGPLAATVADLTIAYRVMSRPNPDDPIQGLYTPSIPPSLSHSPPQKIIAIDEAWWSHAEPSVNAVCRRAVDHFTSRGYATIPIRIPYLREIQLMHSATCITEMQDLARHRHPDPEQWQSLINHANAITMSVGTQTPAGDYMKYAQLRDLLMKHLAFLFEQNPGMLVVTPTTPLPGWPRQPGDDAYGVSDANTTIANMSYVFVANVSGCPAVTAPIGYVDPVQGEGRVPVGLMAMGEWGCEEQLLEWAKEAETYLIKEGRQRPEGWVDVIEVTKNGGLEAKKNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4E6</accession>
    <name>E3Q4E6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_00602</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089478.1">
        <property type="nucleotide sequence ID" value="XM_008091287.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4E6"/>
    <dbReference type="GeneID" id="24405967"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00602"/>
    <dbReference type="eggNOG" id="ENOG502T4QD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_180921_0_0_1"/>
    <dbReference type="OrthoDB" id="3513895at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ25458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="61" mass="6732" checksum="AB32BD945C66F7EE" modified="2011-01-11" version="1">MAKQETKEAPKLPVKVDLALPPLYRGNGSYTENPKGVRDVQFAMPGSRTKPAVFKKWSGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4G8</accession>
    <name>E3Q4G8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_00624</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089500.1">
        <property type="nucleotide sequence ID" value="XM_008091309.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4G8"/>
    <dbReference type="STRING" id="645133.E3Q4G8"/>
    <dbReference type="GeneID" id="24405989"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00624"/>
    <dbReference type="eggNOG" id="ENOG502R9Z1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015502_2_0_1"/>
    <dbReference type="OrthoDB" id="10067394at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47431:SF1">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47431">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="36"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ25480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="598" mass="65643" checksum="015FA9C1DDB5EE96" modified="2011-01-11" version="1">MVSESTSSSGEASDLGDAKPRAGATKSKATIRASLACVPCRSKHVKCDSALPACLRCRLEEKTCYYAKSRRGIRDPRKRSLINDPIGLPPTATESPVSFPSPEVASLEIPINVVGTLPGGWSLMRSPRLSDSITASPTSLLFDLYFTNFHDTHPWLLPKNQLLHQIRTKPEPFHFLASCVAYVGSLFSEAISSEELREKAFSLASGSLPMTCWTVQGLLVLSVAALGESRMDLSGGWMDTATQMALELGMQEKAFADSEPDPFVAESFRRTYWALYWHGNMRAMREDSPTFTLFGVLATTELPCEEWEYQSGEITRPLSLKEYDARDPMSHKSYSSWTYLIDLCRLCGELILPMPALPPGLLSATIDRADSGIVSWLITLPKWKQELVDPGGTVDMILFHAMAYAHDLRIKMQLPLGASGFSTRDLLTLGPLFKASNSSTANTQRSYTSTNPWLECSTALQAGLSTIGLFNFSLPPARYSPACIIGLQRAALPLLDARMYGGAESPALREKLNLLIGVLKIAGEMWPVARNIGNEVIEVLRDVNSRPHRNTTFGPNPTIDAFITDMASSGSVQGPMMFSFSDSRTSEEMFHWNSGITG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5F1</accession>
    <name>E3Q5F1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GMC oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_01062</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089938.1">
        <property type="nucleotide sequence ID" value="XM_008091747.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5F1"/>
    <dbReference type="STRING" id="645133.E3Q5F1"/>
    <dbReference type="GeneID" id="24406427"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01062"/>
    <dbReference type="eggNOG" id="KOG1238">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011025_0_0_1"/>
    <dbReference type="OrthoDB" id="413885at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09630">
        <property type="entry name" value="CDH_like_cytochrome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1210">
        <property type="entry name" value="Cellobiose dehydrogenase, cytochrome domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.410.10">
        <property type="entry name" value="Cholesterol Oxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015920">
        <property type="entry name" value="Cellobiose_DH-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053208">
        <property type="entry name" value="GMC_Oxidoreductase_CD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47190">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47190:SF4">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16010">
        <property type="entry name" value="CDH-cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49344">
        <property type="entry name" value="CBD9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179427" evidence="3">
        <location>
            <begin position="21"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="4">
        <location>
            <begin position="293"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ25918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="786" mass="83266" checksum="0836518225A9E9C6" modified="2011-01-11" version="1">MRSILSGAAALLGLAGTAAAQLRASAYTDPQTGIDFQRFKPGSYPFSFGIAVPETIGTDFIGQMVVPISETGNWGSVSLNGGMLNSLLFVAWADGKDIRTSFRVASAYANPSVYDETKVSAVPIANGTFSPILGWAISNASPSPASDPGATLNYHSAGFGEFGLDIAEPKSAKFQTWSKYAKAVGASPVPGNGTATPGAGNSTIPAPTTSNTTYDVIVVGGGPAGIIAAERLAEKGVSVLFIERGVANAVHLGSKLALPWNNTLTPYDVPGVADVMTTLPGVSFCSDTASTAGCVLGGSSSINGLNFIHPPDRDFERWPAGWNWKDISAAASRLYERNPGTTSPSSDKKYYDDLTFSILSRLLQAKGWTQVDSIASPNEKDAVFSRPSFSIKNRLRAGPARTYMPFAQGLPNFTLKLGTKVVQVIRSGSKVTGVLVQAADGSRQVIKLNQGGKVVLAAGALSTPRVLWNSGISRSDALEIVKSGAATTGVTLPNKADWIDLPVGHSLRDHAQILLKFNSKSNFTAYPFSDIVSNPIKSDLELFQHGSGLIVQGDQRIHLWTSAKGADGRTRYLQGTASVMVNAVFYLRTFLTHGTSSVGELSITASGNTLIKTKPWLVDAEDRKTMSNFVQYWLDLAGAANSTISYVTPSATPTDIIDTQIISGDHWVGTTKMGTDHGRKNNGTAVVDLDAKVYGTDNLFVVDASIHPDLPTGNTQAIIMVAAEHAAEKIAAVTVPGTNPDASKNSGGCAKRSTRRAMRSRRSARLHWMIGPRALSGHVRVFRRGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5F2</accession>
    <name>E3Q5F2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Alternative oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_01063</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089939.1">
        <property type="nucleotide sequence ID" value="XM_008091748.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5F2"/>
    <dbReference type="STRING" id="645133.E3Q5F2"/>
    <dbReference type="GeneID" id="24406428"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01063"/>
    <dbReference type="eggNOG" id="ENOG502SRQT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026659_0_1_1"/>
    <dbReference type="OrthoDB" id="20368at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006004">
        <property type="term" value="P:fucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11296">
        <property type="entry name" value="O-FucT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019378">
        <property type="entry name" value="GDP-Fuc_O-FucTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10250">
        <property type="entry name" value="O-FucT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0294">Fucose metabolism</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ25919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="460" mass="52455" checksum="FBDE409C4313633C" modified="2011-01-11" version="1">MLCESRPLVVFSLGIALIFVWTLRLLGVHEAITDAVSTIFDEAPSHQDAESLFIEQAMSVEYPAPIDYEPIRQICSRTSFRPGLLFTCEGQHGGIGMVRNQILKCVRYAINGGGAIVIPSMALRNAKDITDIETSTEVPLDYLLDHDTFVTHLTNGCPGMRVYERAEDFPFYERRIGEPLSLLGDQFEPHHPKEGLRYPRKWRQFFDEWLDKMSVKDKMQADAPVHIKMEQSFLEYPVRDDGEAFVNEFGKILSFRNETRALAAKIIYKLKEKFALPIDPTVAINPNAYYGAHLRLEKDATSAWEPENWRFSRMDDQFEEQFKNVESSGLSVVYVASGNQTVVDIFAERLHKRLAAGSGRNVTVVTKHDLLQGPDRKQLDGFTFDQLALVDFLVMFKASVFMGVAHSSFPWTIALRRHELSKYSEYGNEGSDLLRDEYSTIMGMEADYPYVDPFVYGIWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5P1</accession>
    <name>E3Q5P1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_01676</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090552.1">
        <property type="nucleotide sequence ID" value="XM_008092361.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5P1"/>
    <dbReference type="STRING" id="645133.E3Q5P1"/>
    <dbReference type="GeneID" id="24407041"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01676"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_27_0_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11063">
        <property type="entry name" value="CYP52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000102">
        <property type="entry name" value="Cytochrome P450 52A5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047146">
        <property type="entry name" value="Cyt_P450_E_CYP52_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287:SF5">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0349">Heme</keyword>
    <keyword evidence="8 11 12" id="KW-0408">Iron</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 12" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="11">
        <location>
            <position position="476"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ26532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="536" mass="60800" checksum="904C37659A6D51A8" modified="2011-01-11" version="1">MGLGEDVLEYVNLKVVVIFGVAAWWLWIAVRRFDETIRLRRLAPGVRGQPLKAHLPGGTDFIYKAVRATMKHKNVEFWTDRLSAVKGWTGERRLLFGLRIVFTAEPENIKAILATQFSDYGKGEPFHQEWNEFLGDSIFTTDGDQWHASRQLIRPQFIKDRVSDLHTFESHIQILLKAIANGGALNGEDQPVNMDTVDGKVLDISELLFRYTLDVATDFLMGQDVKSLSTPRQEFAEAFNEVQRVQSIIARAATARFLVPRFSFRSGLKIINRFVNEFIERALRLSPEELASKTKSDQGYTFLHELASFTRDRKVLRDQIVAVLLAGRDTTAAALSWTLYELGHHPEAVSKLRAEIIEQVGLERAPTYADLKNMKYLQNVMNETLRLYPAVPFNVRLALKDTTLPVGGGPDGTLPLAILKDTPIGYSTFIMQRREDLYPPVSETSAHPSEFSPERWFNWQPKPWTYIPFNGGPRICIGQQFALTEMGYTLCRLFQNFERVESYMDAIDGGDPKLKAEIVLQPGDGVKVAFWRAGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q618</accession>
    <name>E3Q618_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Arginine N-methyltransferase 2</fullName>
            <ecNumber evidence="8">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_01410</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">S-adenosyl-L-methionine-dependent protein-arginine N-methyltransferase that methylates the delta-nitrogen atom of arginine residues to form N5-methylarginine (type IV) in target proteins. Monomethylates ribosomal protein L12.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="8"/>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090286.1">
        <property type="nucleotide sequence ID" value="XM_008092095.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q618"/>
    <dbReference type="STRING" id="645133.E3Q618"/>
    <dbReference type="GeneID" id="24406775"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01410"/>
    <dbReference type="eggNOG" id="KOG1709">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033831_0_1_1"/>
    <dbReference type="OrthoDB" id="19014at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019702">
        <property type="term" value="F:protein arginine N5-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000135">
        <property type="entry name" value="Arginine N-methyltransferase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017408">
        <property type="entry name" value="Arginine_N-MeTrfase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051038">
        <property type="entry name" value="RMT2/GAMT_Mtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026480">
        <property type="entry name" value="RMT2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32379">
        <property type="entry name" value="GUANIDINOACETATE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32379:SF1">
        <property type="entry name" value="GUANIDINOACETATE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038148">
        <property type="entry name" value="Arginine_N-mtfrase-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51559">
        <property type="entry name" value="SAM_RMT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RMT2" evidence="9">
        <location>
            <begin position="210"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR038148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ26266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="447" mass="49631" checksum="0D83229C74BE0836" modified="2011-01-11" version="1">MAIDDSMQARITTDCPDETREILLHAWSHDKPALKKILDEPGKANCQDPTTGETPLHAAIRACGPAAQDEDDLKVEEAKETVQELFLSGAIWNDVDSNNETPGCVAQRLGQSELYKLCVEAGVRAELLFGLLDGYEQLSSGSEMDEDEAVEVVDADAIKAFEADLEAMGNLQDPEEAPELVQVPEAAADADAGAEANEQKKFVPPVVEDPSLSSEEYLRSNLTYSDGKLVDDGGNGVMMAWETDIMRKSVDAVLPGLPAGKRILNVGFGMGIIDTMFHETRPSRHHVIEAHPEVLEHIDKPESKFGIAWEASGPEEGAFKIHRGRWQDVVPKLLEAGEVYDAIYFDTFGEDYSQLKMFFTEFIPGLMDFEGRFSFFNGLGADRRICYDVYAKVVEMHMTDAGLDIEWNELDVDMKGLEEAGTGEWEGVKRRYWTLDKYRLPTCTFMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q632</accession>
    <name>E3Q632_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">EXS family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_01424</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090300.1">
        <property type="nucleotide sequence ID" value="XM_008092109.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q632"/>
    <dbReference type="STRING" id="645133.E3Q632"/>
    <dbReference type="GeneID" id="24406789"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01424"/>
    <dbReference type="eggNOG" id="KOG1162">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024081_2_1_1"/>
    <dbReference type="OrthoDB" id="2159384at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004342">
        <property type="entry name" value="EXS_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10783:SF46">
        <property type="entry name" value="PROTEIN ERD1 HOMOLOG 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10783">
        <property type="entry name" value="XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03124">
        <property type="entry name" value="EXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51380">
        <property type="entry name" value="EXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="104"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="EXS" evidence="6">
        <location>
            <begin position="190"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ26280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="406" mass="46323" checksum="89016366D43EB9F5" modified="2011-01-11" version="1">MDGDPKVESQLDSFSLTFPLPYRIGFVIVLAVWGWGVNLHYLHKVKIDVPSLIRYPSRSSPTQPAHHLSTYRLATVLSTVFFLSISTFWIFTRRTPSLVIEYDWLPMTYLVALAALFFVPVRNFSQGGRSRFLATLRRVSIGGLAEAKDGKFGDILLADVLTSYSKILGDLYVVLCMFFTPAGSSTARPDRNCGGTVMVPLIMAVPFAIRFRQCIIEYLRVRRAPYKESAGWGGQHLANATKYATAFPVIILSALQRSVPADQPAPGLNRAWLMAVLVNSLYSWYWDVAKDWDLTLFSSARERNNPEHPFGLRRRLVFQQPIIYYGVIAMDLMLRCTWTVKLSANLDNFTDFESCIFLLQSLEVFRRWVWIFFRVETEWIRNNTTGLAVDDILLGDYQGKYDSDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q680</accession>
    <name>E3Q680_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cell wall proline rich protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_01472</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090348.1">
        <property type="nucleotide sequence ID" value="XM_008092157.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q680"/>
    <dbReference type="STRING" id="645133.E3Q680"/>
    <dbReference type="GeneID" id="24406837"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01472"/>
    <dbReference type="eggNOG" id="ENOG502RD9J">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007264_0_0_1"/>
    <dbReference type="OrthoDB" id="5406427at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="493"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="563"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="675"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="347"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="454"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="566"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="579"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="675"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="722"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="743"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="777"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="811"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="854"/>
            <end position="869"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="877" mass="93403" checksum="1AB1CB70C2C0823F" modified="2011-01-11" version="1">MAADSADRPSRSPLLPNFTFNPGASLSPDTNSLLSPPLSPPPVSPRLVPSPSRPTGVGHRRGGSEFVGGSIRSGDSITVTGTSPTRSESGFASPNFQLPPPKPVNRRGHAHRRSAALSSHDLSLIVQPTAPGNMRGNSAPTSPADYDRRLGDENGGLNGKTLKGVESEPALRVPPELTRPVTADSGTSSDRALPAERPVTRARVGFSDTLEFIPRPLSMVSSDTSSTVTARPGGHSVSGSISSIISIPTTINAENEPVIPLVLTPSRQTNESRPSTAGAVLERSQSIQSVGASPRRRNSIPTLMNLPEAGTVGPPMPSPTKTPKRWSFFGLDPFAAAASPLRVRPLSSSSSDSGSKPHSSASSSNSEHVSDPITTAGISEQDGQGPDGKKSKKKKKVKNWAGSILARKSKPRNKKCKDLDLSGDSARQFEITEPKDETLMTEPEVNIEPVTPTLVVTDTSSQPQNLQEWKPRPLSAQDDTSFPMIDLDAALGPFNTPLGNNPEWDAAQRAAASTKRQLHSAQGMKGFSGPGMHYHRRAESAPEMVPFEAARFGIHRFGSSSTMADVFEEDEEDDEHTGKSASLHTNSGRRVAQDSEESSGDEATPPATNPVKKPILDIAPVALDDASIRGAPAAADKDATKVAASMKSGESLASLQDDVIVEEPLIPEMSEFRTSSVFQEKAESTASATPSPRRILASKDLSPVDVSPLHLPTPSHVPVSPYSMSHASSFPSPRSPMSYDAQRISTAPSSVNEENNFQSLLLGEPGPEVRLSVDIPSLTSSHSTMTRDSSFAASSQLRQDPIRPDQQRPVSVSSAAFGRRRSSLASLSRLISSSHGERSKLSMEVPCDGENKKNKTSKSKRLSRMMRFWKPKDDTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6E7</accession>
    <name>E3Q6E7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">HMG box protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_01539</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090415.1">
        <property type="nucleotide sequence ID" value="XM_008092224.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6E7"/>
    <dbReference type="STRING" id="645133.E3Q6E7"/>
    <dbReference type="GeneID" id="24406904"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01539"/>
    <dbReference type="eggNOG" id="ENOG502SA5X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048021_2_1_1"/>
    <dbReference type="OrthoDB" id="1919336at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00084">
        <property type="entry name" value="HMG-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09011">
        <property type="entry name" value="HMG_box_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="3">
        <location>
            <begin position="225"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="1">
        <location>
            <begin position="225"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="44"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="84"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ26395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="302" mass="33971" checksum="9C8DEA9CC4173D62" modified="2011-01-11" version="1">MLTAIGQAAKQRLFLRAAPLVGLRAQPVVRAARRGFSTSQWARIPAAKASSTTAKTKKSTEAKDGAAPKKKATAKTKTKEKAATKPKKEKKPVLKKPVKVLTPEEKQKLDVKKWKKLALLPDPKRLPTNKWLVYTAEATKDVKSSTEMMMRVKESGELFKNLSSYELQRLQEKADENKLVNNATYKAWVESHTPQDIAAANRARLRLRKASGRLTPAPIRDDRLPTQPVTPYALFIKARWASGDYAGSLVPEVSSRISKEWRDLSESEKGAYRDLSKADRERYERDALDVLGHVVRRRETSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6H6</accession>
    <name>E3Q6H6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SUZ RNA-binding domain-containing</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_01568</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SZRD1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090444.1">
        <property type="nucleotide sequence ID" value="XM_008092253.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6H6"/>
    <dbReference type="STRING" id="645133.E3Q6H6"/>
    <dbReference type="GeneID" id="24406933"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01568"/>
    <dbReference type="eggNOG" id="ENOG502SDN7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060774_0_0_1"/>
    <dbReference type="OrthoDB" id="5422283at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024771">
        <property type="entry name" value="SUZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024642">
        <property type="entry name" value="SUZ-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039228">
        <property type="entry name" value="SZRD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31796">
        <property type="entry name" value="SUZ DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31796:SF2">
        <property type="entry name" value="SUZ DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12752">
        <property type="entry name" value="SUZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51673">
        <property type="entry name" value="SUZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51938">
        <property type="entry name" value="SUZ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SUZ" evidence="4">
        <location>
            <begin position="68"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="SUZ-C" evidence="5">
        <location>
            <begin position="232"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="83"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="39"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="119"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="184"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="215"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00044802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ26424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="288" mass="31148" checksum="952F1DEC7C97156B" modified="2011-01-11" version="1">MVKKASVPNAWEDDDWESAADKMDGGAPLQPEPPAPLSKAERLAQHAESNRKLWESADTPTPLTFLEAQPSVPLATGFKPQVKVLSRKPAPRTIARRDPVTGQLSHLSLADDDADDEAAEKKPQLTPEEIRAKQQRELEEKQRRYEEARAKIFGESNPSSGASSPGTTTPPRSGENERGGGGRGRSRGRGRGGGHRGNNSSRQEDYRRPGSSRADTVRSESGRELFDPGYAPRGGFAMQKRGGEPGPHSGRSMPRDEEQPKQALRAPRGPDGSGRGGFGFAKRGTKEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6N0</accession>
    <name>E3Q6N0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Luciferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_01622</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090498.1">
        <property type="nucleotide sequence ID" value="XM_008092307.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6N0"/>
    <dbReference type="STRING" id="645133.E3Q6N0"/>
    <dbReference type="GeneID" id="24406987"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01622"/>
    <dbReference type="eggNOG" id="ENOG502S0WG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063954_1_1_1"/>
    <dbReference type="OrthoDB" id="9987011at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048273">
        <property type="entry name" value="Luciferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040841">
        <property type="entry name" value="Luciferase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38695">
        <property type="entry name" value="AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38695:SF1">
        <property type="entry name" value="AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17648">
        <property type="entry name" value="Luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Luciferase" evidence="2">
        <location>
            <begin position="221"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ26478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="310" mass="34503" checksum="1893E8585C11BB33" modified="2011-01-11" version="1">MSVALTTSTSSLLQEEPGGASPNACVGLDINQAAVNCVLKQEPISVTLNGPAIFALSMTLALIIHFLEPRVAECLLVLLPILLLVHNDYHNYLGLGPGGTPATFPGYVRIAWFRLWALRDPFTAPDPDPDRLPKRGILRQDDDPHHWPLPYRPGPRPMVAGIAPQRQLDQHGTVPHYHALRRTLEGLAARNPARFGTARSCLEKHGLGLFARHPVNVTCNGEVCHVHDSDHSLHMNLHPEDIREVLAKGWGQRHPLAWKGSLVRMPVPEEFVMVYAPRDDHELSIVCRIIEAAIWYVISEKTEIRVERAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6N1</accession>
    <name>E3Q6N1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Major facilitator superfamily transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_01623</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090499.1">
        <property type="nucleotide sequence ID" value="XM_008092308.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6N1"/>
    <dbReference type="GeneID" id="24406988"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01623"/>
    <dbReference type="eggNOG" id="ENOG502QW68">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009650_0_0_1"/>
    <dbReference type="OrthoDB" id="3353407at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021822">
        <property type="entry name" value="DUF3405"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36205">
        <property type="entry name" value="CHROMOSOME 19, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36205:SF1">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11885">
        <property type="entry name" value="DUF3405"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="579"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="596"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ26479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="869" mass="99910" checksum="DF8B8DC2956B81FA" modified="2011-01-11" version="1">MGIFSNPLRSRENRTGKLPKYEQLSPLRAKERPSNDDDDDDYYSSDDESEDYSTTSSPSARSSRHTSASLSSAAMMLPKRALATARRPRTHLYRLPNRIIRYLCFGLVTFIILMIMSLVRASHVENKMIMEGKVEKKPDPPPVWESFGFLQRYYGGVRSIVPPSKYIPSYPRSRDELPLDQLEINTTATATSEDGKDDAVRRSVPKSKNILEHPGSIFVTKPEKMNECFIDKDNKVRVPPIRYLEGRPQGFPQHAEGSYEILGLPEDICYERFGRYAPYGFGYSVPAGGLGIGEHGENEGSEDVWETTPKVDWRQVDWADAQRRCYRANNDRFKPMPPKTPSGRGFFVDEPTQNATLVTRDPLENLEPNAKPAQDDKNAGQEQKTEKEKTGRTAVVIRVWDEYDWREEDIMNVRSVIAELSLASGGRYDVHLLVQVKNDAAYPVWADHEVYERRIRERIPEEFRGLVTLWTETQMLSLYQGIFDLFTRGPDLPVHGVYRGLTMAMQYFAYEHPEYDFYWSWEMDIRYTGHYYDLFSKIENWGKEQPRKGLWERNARFYIPSVHGSWEDFRQMARVQSEMGTDGPDNVWKNIPGANKNKEDKNPAKISRGEKTIWGPERPTSEDDWFEIENDPKPPTTYEKDKYTWGVGEEADYISFNPIFDPEGTTWLLSEDITGYNKNNRDEPLPPRRAHIITASRMSRRLLMTMHRETAFKKHFAFPEMWPVTVAFQHGYKAVFAPHPMYVDREWPTEYLAQVLNGGKNGASGGSRTAVFGQREHNLRGLTWFYNSGFAPNLYRRWLGLKVNNDGGEEFEKTEDLSKDGSSVGQMRGGEGRMCLPPMLIHPVKGIEIPVEKIPEAAKENVPESDPNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6N6</accession>
    <name>E3Q6N6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Dipeptidyl peptidase 3</fullName>
            <ecNumber evidence="11">3.4.14.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Dipeptidyl aminopeptidase III</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Dipeptidyl peptidase III</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_01628</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>Release of an N-terminal dipeptide from a peptide comprising four or more residues, with broad specificity. Also acts on dipeptidyl 2-naphthylamides.</text>
            <dbReference type="EC" id="3.4.14.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11 13">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11 13">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the peptidase M49 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.14.4" evidence="11"/>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090504.1">
        <property type="nucleotide sequence ID" value="XM_008092313.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6N6"/>
    <dbReference type="STRING" id="645133.E3Q6N6"/>
    <dbReference type="MEROPS" id="M49.004"/>
    <dbReference type="GeneID" id="24406993"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01628"/>
    <dbReference type="eggNOG" id="KOG3675">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011977_1_0_1"/>
    <dbReference type="OrthoDB" id="4694525at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.540.30:FF:000001">
        <property type="entry name" value="Dipeptidyl peptidase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.540.30:FF:000004">
        <property type="entry name" value="Dipeptidyl peptidase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.30">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005317">
        <property type="entry name" value="Dipeptidyl-peptase3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039461">
        <property type="entry name" value="Peptidase_M49"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23422:SF11">
        <property type="entry name" value="DIPEPTIDYL PEPTIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23422">
        <property type="entry name" value="DIPEPTIDYL PEPTIDASE III-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03571">
        <property type="entry name" value="Peptidase_M49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007828">
        <property type="entry name" value="Dipeptidyl-peptidase_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 11 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6 11" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11 13" id="KW-0862">Zinc</keyword>
    <feature type="active site" evidence="12">
        <location>
            <position position="445"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="444"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="449"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="503"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR007828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR007828-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR007828-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ26484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="704" mass="78652" checksum="0972253EE912F597" modified="2011-01-11" version="1">MNAQELTHYLADAPPSVVRLEIEKHFEPLTDKQKRYAHFISKASFAGTRIVLRQLSPESEPIYDFIVALHKSSGGDWSGLAKKAGVDETQLTYFLEYAAQFLGNNGNYKSFGDAKFIPRAEEKTFAALAATSPEAERFYKATNGAIFSSDKQSLMHLGYPDKGHMTTYYPDSPHITKDEIEAVSAWMEKKGLLPENTRLRKTKEGSFELLIASAVTTVPADGGDTGKQTEFQFEDGLLKDKAIKLVYGDYAAEMKAISEYIKKAQENSDNETQAKMHEAYAKSFTSGSLLDFKDSQRYWIRDKGPMVESNIGFIETYRDPAGIRGEWEGFASVERTRAFGELVSSAPKLIPLLPWSKDFEKDKFLSPDFTSLEVLTFAGSGIPAGINIPNYDDIRQTEGFKNVSLGNVLSAKAPNEKIPFISEADLELYHKYRDPAFEVQVGLHELTGHGCGKLLQETSPGTFNFDEKKPPISPLTNKPVTTWYKPGQTWGSVFGSLAASYEECRAELVAMYLGCEFPVLKIFGFGDGTTDINNEAGNVLYAAYLQMARAGLVALEMWDPKSQKWGQAHSQARFSILQCFLQAGDDFCKLEYKNDDLSDLEIKLDRSKILTTGRDAVGKYLQKLHVYKATADVDNGTAFYKEMTDVDMDFWGTKARNVVLKNKQPRKVFVQANTFLDEASGKVSLKHYEASPAGMIQSWVDREL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7R6</accession>
    <name>E3Q7R6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GMC oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_02099</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ26928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090948.1">
        <property type="nucleotide sequence ID" value="XM_008092757.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7R6"/>
    <dbReference type="STRING" id="645133.E3Q7R6"/>
    <dbReference type="GeneID" id="24407464"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02099"/>
    <dbReference type="eggNOG" id="KOG1238">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002865_4_1_1"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF100">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00630)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180202" evidence="3">
        <location>
            <begin position="20"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="4">
        <location>
            <begin position="352"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="140"/>
            <end position="143"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="299"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ26928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="654" mass="70798" checksum="83BE4870DC6BABF6" modified="2011-01-11" version="1">MRFSRVLGLLATSVSLVGAVDLTGYEFIVVGSGAGGGVLAARLALAGRKTLLIEAGDDQGANDNYTVPAYQAKSTEDDAMAWDFFVRHYADEARQARDFKTTYETPGGGEYTGLQPPPGSKMKGTLYPRAATLGGCTAHNALVAVYPHRSDFEYIARLTGDKSWSADNMRNYFVRMENNRYLLLPLLYGGHGYNGWLSTETAPLNIALLDPQLLSLVTGGAFALGNQTNLVFNVAALLAGDANSPTVDRDTQPSYHQIPITTNDAHRVGSREFVVAVRDAKKPNGSKRYPLDVRMNCHVTKVLFENSSPPKATGVEFLDGRYLYRASPRSRNAGSGIRGTATASREVIVAGGAYNSPQLLKLSGIGPAAELRRFGIPVVKDLPGVGTNLQDHYEITVQGRTPANFSALDGCTFGFYGQQDPCLERWRNPPLLSDRGTYASSGFAAAMLYKSTVAERNEWDVFAFGGPVNFRGYWPNYSVNATIDHDWFSWAILKSHPRNTAGSVTLRSSDPLDVPDIVYNYFDTGSGDYNADLQAMAEAVELTRDAFARQLVPIREMLPGAGVRGNAAVKQYIKDTAWGHHASSTCPIGADNDPMAVLDSSFRVRGVSGLRVVDASVYPRIPGTFTAVSTYMVGEKAADVILNQIINSPGKKGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7V5</accession>
    <name>E3Q7V5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylesterase type B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_02138</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ26967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090987.1">
        <property type="nucleotide sequence ID" value="XM_008092796.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7V5"/>
    <dbReference type="STRING" id="645133.E3Q7V5"/>
    <dbReference type="GeneID" id="24407503"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02138"/>
    <dbReference type="eggNOG" id="ENOG502SRWU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_816380_0_0_1"/>
    <dbReference type="OrthoDB" id="5343383at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142:SF1">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="3">
        <location>
            <begin position="228"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ26967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="340" mass="38263" checksum="794250966F0998A4" modified="2011-01-11" version="1">MSGYDRDVVVDCLKRHYELLVRMGYMEPEAVELPPAGGWSDAELRVDALRAMGRSEAVIDLLRHIPYVHENDDADPVEIYTETFPLRYLRSGRWFGGNPGEDFATTPLLDLGFAPFDGPVPADMVSLTHADEGTWWLVDTKEGCIYPYGTEFDKNADEVPHDQQWRAVDPVPIQAYFDKIHAQVGNLEVVPAPRSGKWEARVVEEYTEEGQFALFLPSNKISRLSVYAATFNGTKLATRYGKTCVQDPIFADVDTQDEACLNFNVFRTRGIPLSQKTPVLVWIHGGAFYAGSYRSFDAAASMPQLRCRLFRLIVQGANHRVLQAKPNEDGVKSHDWKGMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7Z2</accession>
    <name>E3Q7Z2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02175</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091024.1">
        <property type="nucleotide sequence ID" value="XM_008092833.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7Z2"/>
    <dbReference type="STRING" id="645133.E3Q7Z2"/>
    <dbReference type="GeneID" id="24407540"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02175"/>
    <dbReference type="HOGENOM" id="CLU_983553_0_0_1"/>
    <dbReference type="OrthoDB" id="3786931at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="102"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="283" mass="30824" checksum="525701FCD39289B5" modified="2011-01-11" version="1">MQTLTNPQVAMPSFSTGPAQEPPSNSLPTEMLQDESRASNRFRNIATSSLFSNNEPAQPVTLRSEVLLAPGPYTGYGNVAAPSSFYTDTGPARPHPPRIDVSLAAARPPSAPSDLARHDPSHRSRPGASVSNPYARPQDDGPLIQDQPPAGLPYRACPVPPGHPHRPATQEEALRWGEQDEVVERPTFTEYYENKRKPKPLPPSGRRQFYGRRPSPPPFPSPPQHIHPLTSRPQPGSPEIPGSPPALTLEEVRRWSQARGLVAPSDVSTVWPQDSISSVGLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q801</accession>
    <name>E3Q801_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ATP synthase subunit delta, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">F-ATPase delta subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">GLRG_02184</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase epsilon chain family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091033.1">
        <property type="nucleotide sequence ID" value="XM_008092842.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q801"/>
    <dbReference type="STRING" id="645133.E3Q801"/>
    <dbReference type="GeneID" id="24407549"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02184"/>
    <dbReference type="eggNOG" id="KOG1758">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084338_0_0_1"/>
    <dbReference type="OrthoDB" id="270171at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12152">
        <property type="entry name" value="F1-ATPase_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.15.10:FF:000003">
        <property type="entry name" value="ATP synthase subunit delta, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.15.10">
        <property type="entry name" value="F0F1 ATP synthase delta/epsilon subunit, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00530">
        <property type="entry name" value="ATP_synth_epsil_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001469">
        <property type="entry name" value="ATP_synth_F1_dsu/esu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020546">
        <property type="entry name" value="ATP_synth_F1_dsu/esu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048938">
        <property type="entry name" value="ATPD_C_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036771">
        <property type="entry name" value="ATPsynth_dsu/esu_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13822">
        <property type="entry name" value="ATP SYNTHASE DELTA/EPSILON CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13822:SF7">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT DELTA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02823">
        <property type="entry name" value="ATP-synt_DE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21334">
        <property type="entry name" value="ATPD_C_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51344">
        <property type="entry name" value="Epsilon subunit of F1F0-ATP synthase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="11" id="KW-0139">CF(1)</keyword>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATP synthase F1 complex delta/epsilon subunit N-terminal" evidence="14">
        <location>
            <begin position="32"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="F1F0-ATP synthase subunit delta C-terminal" evidence="15">
        <location>
            <begin position="118"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF21334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EFQ27013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="161" mass="17266" checksum="3A8825433663BAB9" modified="2011-01-11" version="1">MNSFRFARAALRARPAAIRAPLQRRTYADAIKLSLSLPHQSIYKSQDVVQVNIPAESGEMGVLANHVPSIEQLKSGLVEIIEESGPSKQFFLSGGFAVVQPNSVLSINATEGYPLEDFSAEAVKSQIAEAQKVASGSGSEQDIAEAKIELEVLESLQAALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q805</accession>
    <name>E3Q805_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_02188</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091037.1">
        <property type="nucleotide sequence ID" value="XM_008092846.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q805"/>
    <dbReference type="GeneID" id="24407553"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02188"/>
    <dbReference type="HOGENOM" id="CLU_2497754_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ27017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="86" mass="9843" checksum="69446508C6791B0E" modified="2011-01-11" version="1">MLVCAPCSSTHHAEHLVPRGPAGHKWRPTERREECKCFRSIGYQEMAPRESTYPYPAMQIRCLEPSCKGDVYACSFENILPVQGRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q888</accession>
    <name>E3Q888_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1996 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_02271</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091120.1">
        <property type="nucleotide sequence ID" value="XM_008092929.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q888"/>
    <dbReference type="STRING" id="645133.E3Q888"/>
    <dbReference type="GeneID" id="24407636"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02271"/>
    <dbReference type="eggNOG" id="ENOG502SI3Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014722_5_2_1"/>
    <dbReference type="OrthoDB" id="74764at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018535">
        <property type="entry name" value="DUF1996"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662:SF11">
        <property type="entry name" value="WSC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09362">
        <property type="entry name" value="DUF1996"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179512" description="DUF1996 domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1996" evidence="3">
        <location>
            <begin position="43"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="377"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="380"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="437"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="498"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ27100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="514" mass="54029" checksum="003AD3C8EBD607D2" modified="2011-01-11" version="1">MKFAAAASLAALFGAASAGSKSDDRTFAVLRFNNKQLVKTRLDPIIDPGKISSHVHGVMGGSNFGMSATGETLAQSKCSNAMISGDNSAYWFPSLYFRDPKTQAFESVDVFYVNVYYFFDGTDDEIKAFPRGLQIFSGNASARAPPSTGAKQNLEPEDGPIQPVQWTCPRSSYDPPSYPANSDGSTAGIVDPNNKGSGVGFPDQNCDGFGSPLRADIHMPSCYNPKAALSDYESMAWPSRKGASNGRRANCPEGWIHVPHMFFEVYWDTPKFASRWTPGQGAQPFVLSNGDASGYSLHADFIAAWDEDVLQQIIDNCNAGSSGMDKCPGLLKGLNTDKDCTISSPLDEVTDGVLQSLPGDNLLSGFSFGPLVGGSGSGSGAAVKPASSAPPVAPAQPSASKAASGAVSQGGAPKTSAAAASSQLPIQVAPVQASTKPAEPTEAAPTAPAVSLGGSEPSKKTSCTRRTRTMWKTVTVTTPSEESGAAAATPEADDYSKARRHVHEHMHRHRSHHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8X8</accession>
    <name>E3Q8X8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Programmed cell death protein 2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_01987</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091512.1">
        <property type="nucleotide sequence ID" value="XM_008093321.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8X8"/>
    <dbReference type="STRING" id="645133.E3Q8X8"/>
    <dbReference type="GeneID" id="24407352"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01987"/>
    <dbReference type="eggNOG" id="KOG2061">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031771_1_1_1"/>
    <dbReference type="OrthoDB" id="443682at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007320">
        <property type="entry name" value="PDCD2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47524">
        <property type="entry name" value="20S RRNA ACCUMULATION PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47524:SF1">
        <property type="entry name" value="20S RRNA ACCUMULATION PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04194">
        <property type="entry name" value="PDCD2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Programmed cell death protein 2 C-terminal" evidence="2">
        <location>
            <begin position="301"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="166"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ27492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="421" mass="45026" checksum="89B0F1B3DA878B33" modified="2011-01-11" version="1">MADYDSDSSEQEFTETNVLLGYATKDADEDTISRLGGRPDWLNPDQPASAALARCKVCNDFMVQLLQLNGELPERFPGHERRLYVFACRRPTCRRKQGSIRAMRGVRISKDAPAVGTKKAETKAPKKTVEEAPKNTDGPGLGSALFGGGGGGGVSGTTNPSASNANPFSTGTSSSSPFSTTAPASNPFSKPAAEPKQPKQPEQQEKEAKDPAASLPKTFAETLNLNNPQTPSGPPPPPEPWPAADALPKPYPLSYLADAEFETLDPEPMSVPQNARMEVDNEGGAGASGGDTKDVFESSMDAVFQKFADRMAQNPEQAIRYEFAGTPLLYSKADAVGKALGGGGRMPRCGNCSAGRVFEVQMTPHAITELEAEELSLEGMDWGTIIVGVCEADCQQRGVQAGEAGYLEEWCGVQWEEMEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q959</accession>
    <name>E3Q959_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Endo-1,5-alpha-L-arabinanase A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_01733</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Glycan metabolism; L-arabinan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091258.1">
        <property type="nucleotide sequence ID" value="XM_008093067.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q959"/>
    <dbReference type="STRING" id="645133.E3Q959"/>
    <dbReference type="GeneID" id="24407098"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01733"/>
    <dbReference type="eggNOG" id="ENOG502SM7B">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010779_2_0_1"/>
    <dbReference type="OrthoDB" id="19657at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08983">
        <property type="entry name" value="GH43_Bt3655-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18828">
        <property type="entry name" value="GH43_BT3675-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046780">
        <property type="entry name" value="aBig_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050727">
        <property type="entry name" value="GH43_arabinanases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43301">
        <property type="entry name" value="ARABINAN ENDO-1,5-ALPHA-L-ARABINOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43301:SF3">
        <property type="entry name" value="ARABINAN ENDO-1,5-ALPHA-L-ARABINOSIDASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20578">
        <property type="entry name" value="aBig_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13385">
        <property type="entry name" value="Laminin_G_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180322" description="Endo-1,5-alpha-L-arabinanase A" evidence="7">
        <location>
            <begin position="23"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="domain" description="Atrophied bacterial Ig" evidence="8">
        <location>
            <begin position="30"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate" evidence="6">
        <location>
            <position position="867"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ27238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1048" mass="113272" checksum="1B875F8035120EA0" modified="2011-01-11" version="1">MQSLNFWLSSALALAAVARGQGDTSNAQRVEAALAALTVINLDDVRGNLYLPTVADGLIINWESNSSSVISSDGVVKRQPVDTPVALTASIEYEGVSQAREFVASVRRAVSLDPFEGYAFSYFTGDSIAGEKIYFAASEGNNALEWTELNGGQPVLTSSFGTKGLRDPFLIRSPEGDTFYVIATDLSIGSGTSWGDSVRFGSRYLEVWESHDLKTWSEQRHVLVSPPEAGNTWAPEAYYDDELGAYLVFWASSLYDASDVNRTGSTYHRMLYATTRDFVTFSETTVWQDAGMSRIDSTVIKSGGTYYRFTKDEGARGTGCSDIIQESSASLRATLDSWTIVDSCIGKKAGTSAVEGPTSFKSNENDVHGDKFYLFVDEYGGRGYIPLETADISNPQWTISASYNLPSSPRHGTVIAVTAAELASLRETAPTRRAVNDDGEILRYDFSKTEGTQVQDASGNGNDAVINGGASVIDGALNFDGIDDFVQLPDNIISGVEDIAIEARVFLDASQQTPYFIYGIGNTVSGSGNGYLFTTGSPYRASIATGDYTTEQTAASSSSLPQGTWMHLVYTISGRTSVIYLDGYEMARNEDVNIDPKDIGNGVTTANYIGKSDYSSDNLFKGQIREFAIFNRSMTAAEVLSRSGNIGAITGVTLADASALRVPAIINTTNSKVLFPVKPGTDVTALAPTFVTADGVTASPASGTIVDLSAEVKYVLKKGDEDVAEWTISAVEMGSPVLPGLYADPNAAVFNGVYYIYATTDGVPGWGGNTFYSWKSTDLVNWTRSEKPFLTLDGANGNVPWAVGNAWAPTITERNGKYYFYFSGQNAALNTKTIGVAVADTPEGPFTAEPEAMILNNEAITSSQAIDPVAFHDPVSGKYYIYWGNGRPLLAELNDDLVSVKWNTVQAMSGLVDFREGLFIVYRDGLYHLTYSIDDTGSENYRVGYATSNSATGPWTYHGVILQKDPSQGILGTGHNSMFNVPGTDSWYIVYHRFAIPGGGGYRRETTIDHVTFDPDTGLINPVVPTLTSVGPETVPQKFRRMSRVMRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAP0</accession>
    <name>E3QAP0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">alcohol O-acetyltransferase</fullName>
            <ecNumber evidence="6">2.3.1.84</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Alcohol O-acetyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_03072</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Displays enzymatic activity both for medium-chain fatty acid (MCFA) ethyl ester synthesis and hydrolysis (esterase activity). MCFA are toxic for yeast and this enzyme could thus be involved in their detoxification by esterification.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>an aliphatic alcohol + acetyl-CoA = an acetyl ester + CoA</text>
            <dbReference type="Rhea" id="RHEA:17229"/>
            <dbReference type="ChEBI" id="CHEBI:2571"/>
            <dbReference type="ChEBI" id="CHEBI:47622"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.84"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.84" evidence="6"/>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ27928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091948.1">
        <property type="nucleotide sequence ID" value="XM_008093757.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAP0"/>
    <dbReference type="STRING" id="645133.E3QAP0"/>
    <dbReference type="ESTHER" id="colgm-e3qap0">
        <property type="family name" value="abh_upf0017"/>
    </dbReference>
    <dbReference type="GeneID" id="24408437"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03072"/>
    <dbReference type="eggNOG" id="KOG1838">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032487_1_0_1"/>
    <dbReference type="OrthoDB" id="5954035at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008126">
        <property type="term" value="F:acetylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004026">
        <property type="term" value="F:alcohol O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047372">
        <property type="term" value="F:monoacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051792">
        <property type="term" value="P:medium-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051793">
        <property type="term" value="P:medium-chain fatty acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000137">
        <property type="entry name" value="EEB1p Acyl-coenzymeA:ethanol O-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050960">
        <property type="entry name" value="AB_hydrolase_4_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012020">
        <property type="entry name" value="ABHD4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10794">
        <property type="entry name" value="ABHYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10794:SF63">
        <property type="entry name" value="ALPHA_BETA HYDROLASE 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005211">
        <property type="entry name" value="Ab_hydro_YheT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="9">
        <location>
            <begin position="124"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="203"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="332"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00050620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00054277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00066969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00080774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR005211-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ27928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="425" mass="47940" checksum="B39EECDEC72D9D04" modified="2011-01-11" version="1">MDWLGHAKINFTHAPSPVSLKEKDGTQTDLLKVCEKITPPCQMNPLLFNGHLQTMWTATKQHGPPVYYRRKVFQAEDKAFEGTFAVDFVTEPFEDADSSLPPRTKYFEQQDFGSLASDDDKPQLIVLHGLSGGSHEIYLRHAIAPLVDSGKWEVCVVNSRGCANSKFTSGILYNARATWDFRQTVKWMRKNFPNRPLFGLGFSLGANMLTNYCGEEGVNCELTAAVVCSNPFNLEVSNKALRRTFLGREVYQRVMGSSMKELIAGHKEAVQKYTNLDLERLQKVTYLWEFDREVQCISWGYPTESAYYRDASSSDAVLAIRIPFFALHSTDDPIAVNEAIPYEEFEKNPYTVLCTTSLGGHLCWFEPGGGRWHAKPVANFFNHMAFNVDHSQLPPKTNGAPPTNGKSIFHFNPVKRKMEIKASSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBD0</accession>
    <name>E3QBD0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Transcription elongation factor 1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_03312</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the ELOF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ28168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092188.1">
        <property type="nucleotide sequence ID" value="XM_008093997.1"/>
    </dbReference>
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    <dbReference type="STRING" id="645133.E3QBD0"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_105983_0_0_1"/>
    <dbReference type="OrthoDB" id="445983at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008023">
        <property type="term" value="C:transcription elongation factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.190:FF:000001">
        <property type="entry name" value="Transcription elongation factor 1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007808">
        <property type="entry name" value="Elf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038567">
        <property type="entry name" value="T_Elf1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20934">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20934:SF0">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05129">
        <property type="entry name" value="Zn_ribbon_Elf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 10" id="KW-0539">Nucleus</keyword>
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    <keyword evidence="8 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 10" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6 10" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="83"/>
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        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ28168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="129" mass="13887" checksum="77150BE557E88D46" modified="2011-01-11" version="1">MGKRKSSSKPQGPKKKDPLPSKFTCLFCNHEDSVAVKLDKKAGVGSLDCRVCGQMFQCSINYLSAAVDVYGEWVDAADAVAKEAGPTAGSQSKIPSARRAPPSRPVNDDDDDDDQRYGGEGVDLDDDEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QC63</accession>
    <name>E3QC63_COLGM</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_03595</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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    </dbReference>
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    <dbReference type="HOGENOM" id="CLU_1758664_0_0_1"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="45"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ28451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="148" mass="16770" checksum="CDF0215A0C9D96CC" modified="2011-01-11" version="1">MSMRFVSVLAYADASTRIMVISTRQLLAKLSHPLQRVGLERQIRACQDGTLEPEEEEEEEEEEEEEEEEEKEDLGSPNEPRPLSTPSTICLPDLDPPFEGIRACNLHPVGPRPYSFVCPQTMLQLPNNREPMPYRGDLGTVPRIPARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3QC91</accession>
    <name>E3QC91_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_03623</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092499.1">
        <property type="nucleotide sequence ID" value="XM_008094308.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QC91"/>
    <dbReference type="GeneID" id="24408988"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03623"/>
    <dbReference type="eggNOG" id="ENOG502RKI8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1455451_0_0_1"/>
    <dbReference type="OrthoDB" id="4802756at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180299" evidence="1">
        <location>
            <begin position="19"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ28479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="190" mass="21216" checksum="F2E1F2A01C1ADCD5" modified="2011-01-11" version="1">MSLLGLASMLSLISLVATLPTLDTQAVSQFKYPWLNMTLSNLESVCRKEQRNELYTCTLKFDLYDPNTEGIVEVNGAHCGAAWEWDGITPNHGPNNSYPSTGVLCWSGGSNAFHFRVAKFRSASRFELYVSHLYRDTRFFKPPYDGRKALVNIAIPEAHPLPPIAPYVPPVDQFEFIATATISRRTDGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QC94</accession>
    <name>E3QC94_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_03626</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092502.1">
        <property type="nucleotide sequence ID" value="XM_008094311.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QC94"/>
    <dbReference type="GeneID" id="24408991"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03626"/>
    <dbReference type="eggNOG" id="ENOG502T4RW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2084672_0_0_1"/>
    <dbReference type="OrthoDB" id="4792227at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179605" evidence="2">
        <location>
            <begin position="21"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ28482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="99" mass="10576" checksum="0BD0057135696664" modified="2011-01-11" version="1">MHTLRIVLLVALGASGTVSAGLLDREALLAARQSSGQDENRIRGSCTQTSNKCNLPGRNAQVCPADYNRVRVPVHNDSDKTGLKADERASARSTVPLAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDC3</accession>
    <name>E3QDC3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Arsenical-resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_04039</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cell membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092915.1">
        <property type="nucleotide sequence ID" value="XM_008094724.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDC3"/>
    <dbReference type="STRING" id="645133.E3QDC3"/>
    <dbReference type="GeneID" id="24409404"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04039"/>
    <dbReference type="eggNOG" id="ENOG502QPKH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022869_0_0_1"/>
    <dbReference type="OrthoDB" id="187348at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015104">
        <property type="term" value="F:antimonite transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015105">
        <property type="term" value="F:arsenite transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046685">
        <property type="term" value="P:response to arsenic-containing substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1530.20:FF:000009">
        <property type="entry name" value="Arsenite transporter, ACR3 family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004706">
        <property type="entry name" value="Arsenical-R_Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002657">
        <property type="entry name" value="BilAc:Na_symport/Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00832">
        <property type="entry name" value="acr3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43057:SF1">
        <property type="entry name" value="ARSENICAL-RESISTANCE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43057">
        <property type="entry name" value="ARSENITE EFFLUX TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01758">
        <property type="entry name" value="SBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005508">
        <property type="entry name" value="Acr3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0059">Arsenical resistance</keyword>
    <keyword evidence="4 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="118"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="180"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="259"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="290"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="319"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="352"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="33"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR005508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ28895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="384" mass="41502" checksum="F80B72097664216A" modified="2011-01-11" version="1">MSSSVSFDVVRGSESNKDKAPAEKLAGGGVNQDVEQQQQNPETDEAQVSSIFKSLGILDRLLALWIFLAMLIGILLGNFVPNAGPALQQAIGLLVMMYPILCKVQYEKLHNVFRTREVWIQLVFSAIVNWVVAPLFMLALSWAFLPDKPGLRNGLILVGIARCIAMVLIWTSLARGDGDYCAILVAVNSFLQIVLFAPVALLFIRVIGQDSSISSISYSTVASAVGVFLGIPLGAAIITRLSLIYTVGNKAYTAKVIPFLAPWSLVGLLYTIVVLFASQGSQVVHQIVSVVRVAAPLVVYFSVIFSATLLVARKLGFRYGLACTQAFTAASNNFELAIAIAVATYGPDSDEALATTVGPLIEVPVLLGLVYFIKWFARRNGWND</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDE2</accession>
    <name>E3QDE2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Transcriptional regulatory protein DEP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_04058</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092934.1">
        <property type="nucleotide sequence ID" value="XM_008094743.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDE2"/>
    <dbReference type="STRING" id="645133.E3QDE2"/>
    <dbReference type="GeneID" id="24409423"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04058"/>
    <dbReference type="eggNOG" id="ENOG502S14R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012439_1_0_1"/>
    <dbReference type="OrthoDB" id="20886at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013907">
        <property type="entry name" value="Sds3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21964">
        <property type="entry name" value="BREAST CANCER METASTASIS-SUPPRESSOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08598">
        <property type="entry name" value="Sds3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01401">
        <property type="entry name" value="Sds3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="607"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="331"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="49"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="123"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="190"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="249"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="260"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="301"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ28914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="638" mass="70392" checksum="C75BC02EAA7F5F0F" modified="2011-01-11" version="1">MAATASAPPALSPGQATLDHDSNISSPLSDVEDKDGEVDSLDGMQLDLPQDDPDEALDSDSNLSEANDTEAETERLFDTPQAQRHKDVVVNQFNDGQVFDRTPSKLQKTFSVDATDDGDDESLSDRDDVSMISSHADEASPSKPKKSTTLPSTEDDTENIDTKKRKRSPVAESSEPGQPARKRTGSVVPHEQDQRKNDVEMQEDEVPSTASHTDDHSATDDNAPELAPIKRGPLRDGHSPVKDLQITKKITRNGSRRKGHAPETNEHEGLDGDGRDDGRNDEDSGPHADDHAEQEGDEDAEASKNDEEMERKRAAVEEWTDLEEKFVVFRERLYKDRLERLEQEEQSLQAEPPSHPEYLNMKQCLDERLEKKLRNIEKEYELSVEALERLAVARRAQIWNQFYQGARESRSKMLEHLNKEWYETQNARRSAHSVPDYGLLFPTNPTQRTRNAVAYNSEVSFLAGLAKHEGFPAVPPMRGANGSEIEDDLEAMKRNSKPRQRSIMQPIEDYQAVAFGGNLGPAGEQFIKDTPWANPNHIAHKITTGPVAPVAGAKPQAAQASKTGAGPSHAHSMPIITNGHAAAHASPHMNRFTSASPEMVRTANVLTQSAQMKRAGSRTSKAAKDTAPKQEPVSAMAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDM7</accession>
    <name>E3QDM7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Amine oxidase</fullName>
            <ecNumber evidence="9">1.4.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">GLRG_04109</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <cofactor evidence="9">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="9">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <text evidence="8">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="PTM">
        <text evidence="8 9">Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the copper/topaquinone oxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.-" evidence="9"/>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ28965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092985.1">
        <property type="nucleotide sequence ID" value="XM_008094794.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDM7"/>
    <dbReference type="STRING" id="645133.E3QDM7"/>
    <dbReference type="GeneID" id="24409474"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04109"/>
    <dbReference type="eggNOG" id="KOG1186">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015739_0_0_1"/>
    <dbReference type="OrthoDB" id="3341590at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008131">
        <property type="term" value="F:primary methylamine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009308">
        <property type="term" value="P:amine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.98.20:FF:000002">
        <property type="entry name" value="Amine oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.40:FF:000018">
        <property type="entry name" value="Amine oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.40:FF:000028">
        <property type="entry name" value="Amine oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.20">
        <property type="entry name" value="Copper amine oxidase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000269">
        <property type="entry name" value="Cu_amine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015798">
        <property type="entry name" value="Cu_amine_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036460">
        <property type="entry name" value="Cu_amine_oxidase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016182">
        <property type="entry name" value="Cu_amine_oxidase_N-reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015800">
        <property type="entry name" value="Cu_amine_oxidase_N2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015328">
        <property type="entry name" value="DUF1965"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638:SF20">
        <property type="entry name" value="AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638">
        <property type="entry name" value="COPPER AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01179">
        <property type="entry name" value="Cu_amine_oxid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02727">
        <property type="entry name" value="Cu_amine_oxidN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09248">
        <property type="entry name" value="DUF1965"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00766">
        <property type="entry name" value="CUDAOXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49998">
        <property type="entry name" value="Amine oxidase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54416">
        <property type="entry name" value="Amine oxidase N-terminal region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0186">Copper</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="4 7 9" id="KW-0801">TPQ</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178387" description="Amine oxidase" evidence="11">
        <location>
            <begin position="29"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="domain" description="Copper amine oxidase N2-terminal" evidence="13">
        <location>
            <begin position="93"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1965" evidence="14">
        <location>
            <begin position="264"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="Copper amine oxidase catalytic" evidence="12">
        <location>
            <begin position="342"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="665"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="673"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="416"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via topaquinone" evidence="7">
        <location>
            <position position="497"/>
        </location>
    </feature>
    <feature type="modified residue" description="2',4',5'-topaquinone" evidence="8">
        <location>
            <position position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR600269-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR600269-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF09248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EFQ28965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="810" mass="91690" checksum="84937ED376B91692" modified="2011-01-11" version="1">MGFSSITQAFGLGALLLLGSDLMPQVNGLPKTPWAQQRAKGHGRKALSQAINKRQFANSSEPADCIPHDPLDIEAPKENIWSGLTGPEAAGVTQWLFAQKELNLTVSDNATAWDNTIALVELMQPNKSDALAYIDGSGPAPARYAHVVLDFRASEDPEYQDILVGPLPVTNDTTKWERLEYPYTRKTSGRVRNLDADDDAMQEWLHKAGKSVADITKDLWNATAQGLDNDTLAIWGIDPYYQDDGRVQRWDTFWSIPGSIFDVQSMLPMGLFFMSDVTGRDPSKWFIEGWYYNGNFYETTEEFRNAYWSGNVEKLGGNFAGDWSATDQQGEILPRDTMAPPTSVAPQGARYSVDPDRKYVEWMGWSFYVGFTRDTGMALYDISYKGQRIIYELGLQEALAHYAGSDPTQSHVAYLDSYYGFGPFAFELLKGYDCPSYATYLNTSFYVDETTHTHLNSICMFEFDADYPIARHSSADYVAATKNVYFTIRSVSTVGNYDYMFSYSFFRDGSVSVEVRASGYIQAAFYAKNDEYGFKIHDQLSGSMHDHVVNFKADFDIFGTENTVQRMHQVPTTQVYPWSKGKAFNTMKLEREFVENEDQGRFDWSYNNQDQLFVLNQDVKNKHGEHRAYRVLPYTGSAHLTVKDSNILKSSGKWAEYDIMVSKRKDTEPRSSHPYNNQDTENPPVNFDAFFDGESLNQTDLVLWFNLGMHHVPHTGDLPTTVFTTAHSGIQFMPANYFDVGQNVETVNMVRINYSNGTTSDVITFGAETDACSLDYEPTEVDLWDYKGDVVVRKFPYSPDDPYYETNAIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDY6</accession>
    <name>E3QDY6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycosyl transferase CAP10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_04218</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093094.1">
        <property type="nucleotide sequence ID" value="XM_008094903.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDY6"/>
    <dbReference type="GeneID" id="24409583"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04218"/>
    <dbReference type="eggNOG" id="ENOG502SJ3D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028539_0_1_1"/>
    <dbReference type="OrthoDB" id="202415at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006598">
        <property type="entry name" value="CAP10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051091">
        <property type="entry name" value="O-Glucosyltr/Glycosyltrsf_90"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203:SF63">
        <property type="entry name" value="GLYCOSYL TRANSFERASE CAP10 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203">
        <property type="entry name" value="KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05686">
        <property type="entry name" value="Glyco_transf_90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00672">
        <property type="entry name" value="CAP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase CAP10" evidence="3">
        <location>
            <begin position="148"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ29074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="461" mass="51966" checksum="537D2A8B8E9575C3" modified="2011-01-11" version="1">MHQRLAARLLWPVIMASALVLVAYGLFFPRSSFQTRLTGRPLDYLLTQQSKSGPSAGTGVNFDNLRLTEEQCRVTFPGLNKEIDAAMSEGDFQLGLNNTSVSLLGQIKDNKILILQAPRPVDMSDQWLERQNAALQQLNRALLTSPTLLPDTFFNLHVQDTPATLSWSHSRPAMSPSPRHIFTMPHFSFWAWNQPFIRSIPHAAAAITDIEASLSFDMKDRRAVWRGTAWFNNGASANPRSRQELLRITKDASWADVQALEWVDSGENATNALMIEDFCRHKYIIHTEGVSYSGRLQFHQLCESVLLSPPMEWMQHTTHLIKPVYSSILLGHEQERQDDGGGATTKPEDGYPSSRARKTWPATVSPGEANAVFVNPDWSDLEATIGWLEEHAEVSRGIARRQRAISFERGYMSPAAEVCYWRALVRGWSKVVRINGTIKESRESTSFEEFVTNAKMSRKGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QE20</accession>
    <name>E3QE20_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">M protein, serotype 2.1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_04252</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093128.1">
        <property type="nucleotide sequence ID" value="XM_008094937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QE20"/>
    <dbReference type="STRING" id="645133.E3QE20"/>
    <dbReference type="GeneID" id="24409617"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04252"/>
    <dbReference type="eggNOG" id="ENOG502QVZ5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015321_0_0_1"/>
    <dbReference type="OrthoDB" id="2121319at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38120">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38120:SF1">
        <property type="entry name" value="M PROTEIN, SEROTYPE 2.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="197"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="395"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="496"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="241"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="22"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="197"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="208"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="396"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="549"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="621"/>
            <end position="631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ29108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="631" mass="68902" checksum="54F16901A5951BB1" modified="2011-01-11" version="1">MSAATAKKPPAAGVGRVSSTDPATSPSVSPARTPTRSSTPTAATATRRAPARSGTPVSARAAAVSRRNSIMGNSNNNGNTEAEEAVRAETVALLDDLKERLSKAEVSSDQYRKQVEVLQTRLDDAIKESSKLEEKVHEAEEQIETLRKEKRDAAKKMREMEAIYEAERSSMTKEKEEMSNREEEMQTIIQRLKDTLSQRANDEEGRPSRQSATSSPNIDNGSFAPPSSLNRSDSRNNSKILLQKDKLIESLRLELAEAQIKLVESENQGGGRLQEVERLLMEARMANARLMEDNESYQLLLQEKTLNGDFSKNDFSYMSASANQDALNALEGRPRGASLADELSDDASDPGNDNEHVRRLESEVKSMKDQNKALTLYINKIIERLLQHQDFEHILDTSSEPKPPGANTNKDLPPPPPKEGASGASLLQRAKTMAAGPNKPRPRPMSYMPSAQPANSAHTDPETAPRIPIGNLTRSSSTRRARPMSEQFTGVNLVNQMYRGPDGPISPPLGSPRTPRTSQTFIGGNPHAAARATSGQQAPTAGNFPGMRSDTSSTSGDSNGLTTPPSQSPPRSHHEKQTTFAGNKPRPLRLVQENNETKQENNKRSSWMGWASGWGKKDESPTASSNEAIPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEB1</accession>
    <name>E3QEB1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04343</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093219.1">
        <property type="nucleotide sequence ID" value="XM_008095028.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEB1"/>
    <dbReference type="GeneID" id="24409708"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04343"/>
    <dbReference type="HOGENOM" id="CLU_2108840_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="115" mass="12564" checksum="7942DCA4AC8F9679" modified="2011-01-11" version="1">MSLALHNRDVGITGAIALLQLPCECTEPSAGSRQDMSPVPQQATSNYHDAQQVQPLDYSEPCLSRGIRGIETLSRETRSSYPRSLEINLATLKTRAGKRLKDIKELRNAEAIGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEP4</accession>
    <name>E3QEP4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_04494</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093370.1">
        <property type="nucleotide sequence ID" value="XM_008095179.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEP4"/>
    <dbReference type="GeneID" id="24409859"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04494"/>
    <dbReference type="eggNOG" id="ENOG502SYS1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089720_1_1_1"/>
    <dbReference type="OrthoDB" id="2129069at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ29350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="218" mass="23412" checksum="4FF3531937141F71" modified="2011-01-11" version="1">MFCSSLRKRPEWTPAIPLLAGSTPRLQESRLSTHDIALPLPQQQQQGRFLRLVLLSPKDVGTAATEERMERLFNLDGGRDAVVVFLLDQQGRGTNPTEAFMALQIEILNKLELPLVPLASVAALPSTLANLQTVPATTQPTDSPAQVAPISLLQHMSSGSGPLSEHAANLLSELGRSPCEVAVLAATDQGRAQILDLLGPAEGTRVLTFLAQERPVFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3QF20</accession>
    <name>E3QF20_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Alcohol dehydrogenase GroES-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_04602</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093478.1">
        <property type="nucleotide sequence ID" value="XM_008095287.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QF20"/>
    <dbReference type="STRING" id="645133.E3QF20"/>
    <dbReference type="GeneID" id="24409967"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04602"/>
    <dbReference type="eggNOG" id="KOG0024">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_11_5_1"/>
    <dbReference type="OrthoDB" id="5363962at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003939">
        <property type="term" value="F:L-iditol 2-dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006062">
        <property type="term" value="P:sorbitol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05285">
        <property type="entry name" value="sorbitol_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045306">
        <property type="entry name" value="SDH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161:SF25">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G14390)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161">
        <property type="entry name" value="SORBITOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="9">
        <location>
            <begin position="13"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ29458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="378" mass="40181" checksum="3AA85A611054CCEC" modified="2011-01-11" version="1">MSSIQVQTAVLHGAKDLKIEQRELPALAPGEVQIAIKATGLCGSDLHYFTHFRNGDILVREPLTLGHESSGVVTAVASDVSNLAAGDRVALEVGQPCEACDLCAMGRYNICKGMKFRSSAKAFPHAQGTLQELVNHPAKWCHKLPETVSLEFGALAEPLSVAMHARDRASLPSGSTVLVFGAGAVGLLCAAVSKADQQRVVIADIQADRVQFALDNGFADAGVVVPALRPQTIEDKLSYAKDVAELVKQAKIGGEEVGELNATYECTGVETCMQTAIFSTRPGGKILIIGMGTPIQTLPISAAALREVDFIGVFRYANTYPKAIDLIATKPKGLPALEKLFTHRYKGLSAIKDAFDMAAQVKDENGNLVLKVLVDTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFT3</accession>
    <name>E3QFT3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetoacetate-CoA ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04912</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093788.1">
        <property type="nucleotide sequence ID" value="XM_008095597.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFT3"/>
    <dbReference type="STRING" id="645133.E3QFT3"/>
    <dbReference type="GeneID" id="24410277"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04912"/>
    <dbReference type="eggNOG" id="KOG1175">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_3_3_1"/>
    <dbReference type="OrthoDB" id="10253869at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030729">
        <property type="term" value="F:acetoacetate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005914">
        <property type="entry name" value="Acac_CoA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01217">
        <property type="entry name" value="ac_ac_CoA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42921:SF4">
        <property type="entry name" value="ACETOACETYL-COA SYNTHASE (AFU_ORTHOLOGUE AFUA_8G04770)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42921">
        <property type="entry name" value="ACETOACETYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="1">
        <location>
            <begin position="116"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="706" mass="77711" checksum="DA3022BCC3F442A4" modified="2011-01-11" version="1">MDTTEIPRKLWEHPDPRSTQMYQFLQSVNSAFNLQLKTFNDLHNWAVANRASFYGHLFTYANFIHEGHPSLVVDESLPIDAVPKWFPGVYLNWAENLLFSRNASDPIGYHGTTGKEDDKVAVTEIREGNRGDVRNLTWGQLRRDAGSLAAAMKARGVTEGDRIVLVGANSIETLLVFTAATWLGAIFSSSSTDMGVKGILQRTTQVDPKFIFFDDATVYNGKTVDLRGKMAEVVSGMGSCPSFSGVISIPRFSKPYDVTSSKTETWSSFLGSPSAPPPFTRIPFHAPFLIYYSSGTTGIPKAIVHTVGGVMLNCFKEGRLHEEMSSESVCLQYTTTGWIMYLSNVAALLAGARAVMYDGSPFVPDLASFIRILGEQRVTKLGISPRWMFEVAKNKISPRHVTDLSSLRVVTSTGMVLSDQLFEWFYDVGFPKHVHLANLSGGTDIAGCFGMENPLDPVYVGGTQGPSLGVPIAIYDAELQNGKGKAVPHGTPGELVATAAFPNIPCYLWGDTTVISPSSTSFASAKPGTKYHSAYFARFDHVWAHGDFCSIHPKTGNISFLGRADGVLNPSGIRFGSAEIYAVIERNYSSKIVDSLCVGQRRPSDDDESVMLFLMMREGETFDRKLVAEVKDAIKRELTKRHVPKYVFQTPEIPTTVNLKKVELPVKQIVSGHTIKPSGTLLNPQSLDFYYQFAKVEEITPGKEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFZ2</accession>
    <name>E3QFZ2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_04971</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093847.1">
        <property type="nucleotide sequence ID" value="XM_008095656.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QFZ2"/>
    <dbReference type="GeneID" id="24410336"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04971"/>
    <dbReference type="eggNOG" id="KOG0054">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_27_1_1"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18597">
        <property type="entry name" value="ABC_6TM_YOR1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18606">
        <property type="entry name" value="ABC_6TM_YOR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000565">
        <property type="entry name" value="ABC bile acid transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002040">
        <property type="entry name" value="ABC multidrug transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000010">
        <property type="entry name" value="Multidrug resistance-associated ABC transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF464">
        <property type="entry name" value="ABC-TYPE TRANSPORTER CICA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="348"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="374"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="449"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="488"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="886"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="921"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="998"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1023"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1110"/>
            <end position="1128"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="185"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="603"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="886"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="1197"/>
            <end position="1440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="43"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="283"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="554"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="825"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="66"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="594"/>
            <end position="604"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ29827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1470" mass="163029" checksum="1D893A0663B59285" modified="2011-01-11" version="1">MADKDEKTNITAPDPQAAAVEPITANAQEDTAFAIDIDKAVEEDGGSQFHEKRARPGLKATKSHATDTSVATTTATRRQPESKPWYKTPNPLRWGGIPPVPEEKIVSREYKASFFSLLTFQWMAPIMTAGYKRQLEPNDIWAVNPDRATDVMTDKFKAAFKKRVDRGDKYPLWWALHETYFFEFWLGGLLQLMATVFQVMSPFTLRYLIQFANDAYDASRRGSPPPPIGRGIGLVLGVTFMQIFQSLGTNHFIYRGMMMGGQSRAVLISVIFEKAMSLSGRAKAGGIKEPANSPPVAEKGNKEGKKKGKKSDASRGPGVLGDGTGWGNGRIVNLMSVDTYRIDQASALFHLSWTAPISCVITLVVLLINLSYSALAGFALLVAGLPLLTRAIRSLFKRRMAINKITDQRVSLTQEILQSVRFVKYFGWETAFLERLKEIRKREIHSIQILLAIRNAINAVSLSLPIFASMLSFVTYSKTNNALNPAQVFSSLALFNGLRIPLNLLPLVLGQVVDAWSSIKRIQSFLLAEEQEEDVVLKPDGENALEMTNASFTWERTATQESEKTVARAGKGAKKGAPKPSAVSKATPKPDEPLNSSGDSTGDEASTLVEEEREPFKLQDLSFEIKRDELVAVIGTVGSGKTSLLAALAGDMRKTSGEVVLGASRAFCPQYAWIQNTTVRDNILFGKDMDKEWYQEVINACALRPDLAMLPNGDLTEIGERGITISGGQKQRLNIARAIYFDSDIVLMDDPLSAVDAHVGRHIFDNAILGLLKGKCRVLATHQLWVLNRCDRIIWMEGGKIQAVDTFDNLMRDHRGFQQLLETTAQEEEKDDAPQTNLAEAPQGDKKKNKKGAALMQQEERAVSSVPWKVYGDYIRASGSILNAPFLFFLLILSQGANLMTSLWLSYWTSNRYPLSEGQYIGIYAGLGALQAILMFIFSLLLSILGTKSSKVMLRQAVTRVLRAPMSFFDTTPLGRITNRFSRDVDVMDNTLTDAMRMYFFTLAMILSVFALIIAFFHYFAIALGPLFVIFILASSYYRASAREVKRFESVLRSTVFAKFGEGLSGVASIRAYGLKDYFISDLKKAIDEMNAAYYLTFSNQRWLSTRLDLIGNLLVFTVGILVVTSRFNVSPSISGLVLSYILGIVQMIQFTVRQLAEVENGMNAVERIQYYGTQLEEEAPLHTIEVRPSWPEKGEIVFDNVEMRYRANLPLVLSGLSMHVQGGERIGIVGRTGAGKSSIMSTLFRLVELSGGHISIDGVDISTIGLHDLRSRLAIIPQDPTLFKGTVRSNLDPFSEHTDLELWSALRQADLVPADANLGDPRSKDSSVIHLDSVVEEDGLNFSLGQRQLMALARALVRGSRIIVCDEATSSVDMETDDKIQNTIATSFRGRTLLCIAHRLRTIINYDRICVMDAGRIAELDTPLALWQREGGIFRSMCDRSGIRLEDIRNASDSTRSEIQEGHSNQSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGJ7</accession>
    <name>E3QGJ7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">S5 DRBM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_05129</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uS5 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ29985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094005.1">
        <property type="nucleotide sequence ID" value="XM_008095814.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGJ7"/>
    <dbReference type="STRING" id="645133.E3QGJ7"/>
    <dbReference type="GeneID" id="24410494"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05129"/>
    <dbReference type="eggNOG" id="KOG2646">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037994_1_0_1"/>
    <dbReference type="OrthoDB" id="309483at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000041">
        <property type="entry name" value="37S ribosomal protein S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000851">
        <property type="entry name" value="Ribosomal_uS5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005324">
        <property type="entry name" value="Ribosomal_uS5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013810">
        <property type="entry name" value="Ribosomal_uS5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48277">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48277:SF1">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00333">
        <property type="entry name" value="Ribosomal_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03719">
        <property type="entry name" value="Ribosomal_S5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50881">
        <property type="entry name" value="S5_DSRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="S5 DRBM" evidence="6">
        <location>
            <begin position="325"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ29985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="489" mass="54859" checksum="09564C34450F367C" modified="2011-01-11" version="1">MNSVRPARSVLSRCVSVSSTPALPCRLFHSSVSRSGRRRSRFNNVTAEQMGLTTPDKIESYAKRQFPDYTEEEKAALKQKYTPEQWEALEAAEAAIDPKDLVIQGRLRTDPYKQPYIEDFATIQPIIDAKPQKTMQPKEVKWLPRREWVDDYIEKMADRVDTQLKDTMGQAFARALRKVKKMNPDKLDFTEEELKELETNPELRRKFLVDQDADVLGGNEPRAPVQSEIAGDNWMELIDKHFFEELQQSLSTDQNPLRPSRLDSWKAIEGEDGNSALSPELGKIEGVKGLYKPPEDPEDDGLDPTGSYMNLKQITGMKMTDILSILTKRVVFRSVSNQTRLGKIRSASVIVVAGNGDGRLGLGEAKSTDSSIATATATLLAIRNMKPIRRYENRTIYGNVEAKISGTVVKLAARPPGFGLRVSHRIFEMARLAGIHDLAASIPRSNNPYNTVYAAYKALLNQPNPEDIAIGRGKKLVDVRKVYYGGSVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGL1</accession>
    <name>E3QGL1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Snf7 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_05143</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ29999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094019.1">
        <property type="nucleotide sequence ID" value="XM_008095828.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGL1"/>
    <dbReference type="STRING" id="645133.E3QGL1"/>
    <dbReference type="GeneID" id="24410508"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05143"/>
    <dbReference type="eggNOG" id="KOG3229">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069208_0_2_1"/>
    <dbReference type="OrthoDB" id="2329734at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000815">
        <property type="term" value="C:ESCRT III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904669">
        <property type="term" value="P:ATP export"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070676">
        <property type="term" value="P:intralumenal vesicle formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005024">
        <property type="entry name" value="Snf7_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10476">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03357">
        <property type="entry name" value="Snf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="185"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="21"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="205"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="219"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ29999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="228" mass="26129" checksum="72B10D7A2FD18871" modified="2011-01-11" version="1">METLKALFVKPDPQQQLRKCNALLRANVRKLDRDINQVRQVEAKTKNLILQADRRAQRDPTRQKQAQKEARDFARELIRARKTSNRLVTSKAQLNSVQMQVNEAFAVRKIEGSIRASVGVMKDVNRLIRLPELAGTMQELSVELMKAGIIEEMVGESLPEDMDEFEEEEAEGEVDKVLGEILKDRMPKEQMPAAPVHQEPKPVEAEEEEEDAEAMMDQMRNRLEALRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGW4</accession>
    <name>E3QGW4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="23">RNase3 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">GLRG_05246</name>
    </gene>
    <organism evidence="24">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Dicer-like endonuclease involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway. Produces 21 to 25 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs leading to sequence-specific suppression of gene expression, called post-transcriptional gene silencing (PTGS). Part of a broad host defense response against viral infection and transposons.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the helicase family. Dicer subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ30102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094122.1">
        <property type="nucleotide sequence ID" value="XM_008095931.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QGW4"/>
    <dbReference type="GeneID" id="24410611"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05246"/>
    <dbReference type="eggNOG" id="KOG0701">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000907_4_6_1"/>
    <dbReference type="OrthoDB" id="416741at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050688">
        <property type="term" value="P:regulation of defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030422">
        <property type="term" value="P:siRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18034">
        <property type="entry name" value="DEXHc_dicer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1520.10:FF:000032">
        <property type="entry name" value="Dicer-like protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.380">
        <property type="entry name" value="Dicer dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="entry name" value="Ribonuclease III domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038248">
        <property type="entry name" value="Dicer_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005034">
        <property type="entry name" value="Dicer_dimerisation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014720">
        <property type="entry name" value="dsRBD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14950">
        <property type="entry name" value="DICER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14950:SF37">
        <property type="entry name" value="ENDORIBONUCLEASE DICER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03368">
        <property type="entry name" value="Dicer_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00636">
        <property type="entry name" value="Ribonuclease_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51327">
        <property type="entry name" value="DICER_DSRBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50137">
        <property type="entry name" value="DS_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="3" id="KW-0930">Antiviral protein</keyword>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="16" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="11 15" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="20">
        <location>
            <begin position="72"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="21">
        <location>
            <begin position="420"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="domain" description="Dicer dsRNA-binding fold" evidence="22">
        <location>
            <begin position="605"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="domain" description="RNase III" evidence="19">
        <location>
            <begin position="952"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="domain" description="RNase III" evidence="19">
        <location>
            <begin position="1139"/>
            <end position="1322"/>
        </location>
    </feature>
    <feature type="domain" description="DRBM" evidence="18">
        <location>
            <begin position="1352"/>
            <end position="1422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="560"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00025403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS51327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="EFQ30102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1447" mass="162187" checksum="F3D0CF3F92656C36" modified="2011-01-11" version="1">MPGYSQSFSDDGSGPSEDVMPADVPASGPQNQDVLSAAAEDVFLDNEVSLPSDEPAPGIPVIMNARAYQTEMFDQSMRQNIIVAMDTGSGKTQVAVLRIRAEVERTSSKHIVWFLAPTVSLCAQQFAVLQSQIPEVQIKFLSGDDNVDSWSDQRTWDEVLHNVRIVVSTYQILLDALSHAFVRMERLSLIVFDEAHNCIGKSPGSKIMTVFYHEEKGKGRYTPHILGLTASPTFGSKVEGINALEATLDAVCKSPTVHRSDLLACVKKPTMTYISFQPHRCYDPPGSLQSLRKAIRSLDILDDPHILHLQSEGTERSQRALMVALESHDTWIQNQMTSFGRQANQIFNDLGPWAAEYYIWVVKSRFMAALRSQSISLNTWKDDEKEYLAKILNQVECQCPPEETIGGDVLSEKVFLLIEQLLQDKTDIMGVVFVRERATVSVLCHLLASHKLLRARYRMGAMVGTSQFQARKRDIWDLSRSEDLQSLHQFRNGKTNLLIATSVLEEGIDVPACNVVICFDYPPNLKSFIQRRGRARMKDSKLLMLHDSSESAPKEWAALEAEMKSQYEEKERELEHLKEVEDTEESTEMIFVINQTGAVLDPENAKQHLDHLCRILSPGEFIDWRPDYIIKKLGAVDAPDIRATVVLPSYLPSHVRTAESQMAWKSEKNATKDAAFQAYVGLYKAGLVNDNLLPFKPEDFVPGVGKVPAILQVNGLLNAWVKVAEAWKVGDSLRSTRILLKDSAGALQGEYEMVLPVWIPGLQTIPVHLDYHITWSLEFGEQLPIDELTGKDDTAVLLALPYSHRWMPTDAQQVVRFSVTDGADLSVTQIGVNQFVQGQMSAHDMTCFIRDQSGSPHTYEGIIPKKPASQSVQKTFYEFETAPEDVPYIALNKWSRRSDFLHRPQSEPGQSPSSSKPYSRVYPMPWAKVDTIPAKYAQFGVLIPSILHHIETRLVARELSLGLLRPLAISDLSLILTAISTGSASEPTNYERIEFLGDSILKFSATINVAALNPQWPERLLSFHKDAIVSNSTLCKAAVKHGLDRYILTKPFTGQKWRPIYVDSVLSRGEDKSMRKMSTKTLADIVEALIGASMIDGGLDKALKCMSIFLQQINWRTLDACRLALYNFSPPDVELPSTLEPLEHLIGYKFDRKTLLIQAMTHASFNLGNPFGCLERLEFMGDSVLDYVVVNRLFAVEPPLPHQTMHLLKTAMVNGDFLGFLSLEQSIGQDEVVLGENTGKEPNLQHSRFSLPLWKFMRHQSPAIGLEQINVHKRYTALRDQIIDSMERGKTYPWALLARIQLRKFYSDIFESLLGAVYVDSGDLGVCARVVERFGITGYLDRILRDGVHVLHPKEELGHLADKEKVTYVLNARQAGDDAAEEKEYLCRVLVGTRCVVEVDGGVTREEVKVKAAEAAVNILKAEKIAEKIQEMPVLEDRDTAMEHASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHH8</accession>
    <name>E3QHH8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_05293</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697348">
        <property type="protein sequence ID" value="EFQ30149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094169.1">
        <property type="nucleotide sequence ID" value="XM_008095978.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHH8"/>
    <dbReference type="STRING" id="645133.E3QHH8"/>
    <dbReference type="GeneID" id="24410658"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05293"/>
    <dbReference type="eggNOG" id="ENOG502QTIK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015590_3_0_1"/>
    <dbReference type="OrthoDB" id="2578740at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3020.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005674">
        <property type="entry name" value="CocE/Ser_esterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000383">
        <property type="entry name" value="Xaa-Pro-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013736">
        <property type="entry name" value="Xaa-Pro_dipept_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050585">
        <property type="entry name" value="Xaa-Pro_dipeptidyl-ppase/CocE"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00976">
        <property type="entry name" value="CocE_NonD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43056:SF10">
        <property type="entry name" value="COCE_NOND FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G00600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43056">
        <property type="entry name" value="PEPTIDASE S9 PROLYL OLIGOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02129">
        <property type="entry name" value="Peptidase_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08530">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00939">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xaa-Pro dipeptidyl-peptidase C-terminal" evidence="2">
        <location>
            <begin position="330"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ30149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="591" mass="66008" checksum="9006CE3CEA228163" modified="2011-01-11" version="1">MSTTQSLDSHIPVEPLSPPIVGRDGYTGLNPRTEVLSKGWKHPHKDARPLPCDIQIDHDVAITTRDGTVLYADVLRPPNTDEKVPAIICWSPFGKKFNGLSSLDYMTPWQLGVPSQTLSGLEKFEAPDPADWVPRGYAIVNVDTRGVFDSGGTMVILGSVEAEDGYDTIEAVARMGWCDGRVGLAGNSHLAIAQWFIAALRPPSLKAIAPWEGCGDLYREQFARGGIYAGDMFDELIVKHMLKGRNGMESFREMFKQHPLANAWWNDKRPDMKKINVPTYITGTWTNTMHGMGAIRGWLEVDSSDKWLRWHPWQEWYDLWGNPQAKEELFSFFDHFLKGVDNGWEKTPKVRMALLRFGNKVPQAIENIVEEDFPPARTQYREYYLSPDGSLAPGGAAPAEAATVSYDSEAGGSVGFTHTFAETTRVMGLPKAVLYMSCADHDDMDVYVMIQKLDRDGAQMKNLNVPWKGIPVKTFDEFKREQETEVVLYKGPVGILRASHRAVDEARSMHPHWPFHPHEREDKVPPGEVVRLDIGIWALGVEFEAGESVRVVVSGESLAVNNFGKNHSLNKGRHIVHLGGGQASHVILPFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHR5</accession>
    <name>E3QHR5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_05547</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697349">
        <property type="protein sequence ID" value="EFQ30403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094423.1">
        <property type="nucleotide sequence ID" value="XM_008096232.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHR5"/>
    <dbReference type="GeneID" id="24410912"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05547"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_1_1"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF2">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="190"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="309"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="339"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="367"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="407"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="435"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="23"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="496"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="512"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ30403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="528" mass="58752" checksum="89F4374913F12DE9" modified="2011-01-11" version="1">MLDFLRTHNYKVTTHITSNLLMVTMIFGMSVFTFGYEGSTLNTIQAMTPFEKRFGDFLPETHDYGFTSNKLAYMNSFPLLIYAVGVIVGAQIGERWGRRLVFVLTNIVCLGGTITVYTAKNYSQLLAGRMIVNFHVGMEAFLIPMFQAEIAPAPVRGSLTAIYGVNGVFASFIASVVTDVTSKYQDDRCWKIPVGIGFIFPAFSLFFWALIPESPRWLLRKGDYANAVKNLDYIYGAMPNYDAEKEAKLLQEALNTSETKGKWKDLVKGPNLRRTGNGLIASALSQLSGSSFSNLYGTIFLKSLKVIDPFMATMVKRALLLATAIVFMFTIDKAGRRPLFLYMGFMQTAVLMVMGGLGTIAHPTLDINKGIVAMTMMFPIFHFVSFGGPLQLTKTEIPHITLRDKSVMLFWLTANLCNFIASFTLPYLLQEPANLGSRVGLIYGSISALGLVWGWFCMPEMSNKSLEEIDEMFAAGVPAWKSRHWRGEQTAKITELESHGAVSDSDSERNSIAKSQTEPTIQEKQSKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QI53</accession>
    <name>E3QI53_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_05812</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. TCR/Tet family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094688.1">
        <property type="nucleotide sequence ID" value="XM_008096497.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QI53"/>
    <dbReference type="GeneID" id="24411177"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05812"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_22_1_1"/>
    <dbReference type="OrthoDB" id="10021397at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000489">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000196">
        <property type="entry name" value="MFS toxin efflux pump (AflT)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1720.10:FF:000012">
        <property type="entry name" value="MFS toxin efflux pump (AflT)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF177">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="65"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="289"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="331"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="372"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="398"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="428"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="461"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="532"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="11">
        <location>
            <begin position="68"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ30668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="565" mass="59541" checksum="1E6B030F5B333BDA" modified="2011-01-11" version="1">MTSPASTLVPAREKGETDRDSTTSPSVLGDTVEKKEETGTATDEEAGSTQPTDATEAVYPTGIRLTFVIVALVLSVFLVALDMTIVATAIPKITDEFRGLDQVAWYGSAFFMCVAAFQSTWGKAYKYFPLKTSFLLSIFIFEIGSLICAVAPNSVALIIGRAIAGVGAAGVASGAYTIIGFSAPPDKRPTFTGIVGAAYGIASVIGPLIGGAFTDHVSWRWCFYINLPIGGVSVAIILLYFTTPPHAVPVKASLREKFLQMDLIGTFLIMGATISFLLALQWGGHTHPWNSSTVIGLFVGFFVILIAFIILEWYQGERSMIAPRLISDRTVLISSVYAFFFGGAYFILVYYLPIYFQSVDNASPTQSGVRNLPLILAVTIATIVSGVSISATGIYTPILVGSAAIATVGAGLLYTLDVGTGSDKWIGYQILAGLAWGAGFQVPIIAVQGTVSADDLASSTAVLLFFQTVGGAFYVAAAQSGFLITILKEVAENLPSVDPAVVALTGATQIRTAFPAEVVPGIIRAYMEGLKIAFALAITGAGVAFLVSLGSRWNKLNTKNLTGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIE6</accession>
    <name>E3QIE6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mannose-6-phosphate isomerase</fullName>
            <ecNumber evidence="5">5.3.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Phosphohexomutase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Phosphomannose isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_05700</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-mannose 6-phosphate = D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:12356"/>
            <dbReference type="ChEBI" id="CHEBI:58735"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="5.3.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the mannose-6-phosphate isomerase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.8" evidence="5"/>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094576.1">
        <property type="nucleotide sequence ID" value="XM_008096385.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIE6"/>
    <dbReference type="STRING" id="645133.E3QIE6"/>
    <dbReference type="GeneID" id="24411065"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05700"/>
    <dbReference type="eggNOG" id="KOG2757">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026967_0_1_1"/>
    <dbReference type="OrthoDB" id="6605218at2759"/>
    <dbReference type="UniPathway" id="UPA00126">
        <property type="reaction ID" value="UER00423"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004476">
        <property type="term" value="F:mannose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009298">
        <property type="term" value="P:GDP-mannose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07011">
        <property type="entry name" value="cupin_PMI_type_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.441.10">
        <property type="entry name" value="Phosphomannose Isomerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001250">
        <property type="entry name" value="Man6P_Isoase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016305">
        <property type="entry name" value="Mannose-6-P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046457">
        <property type="entry name" value="PMI_typeI_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00218">
        <property type="entry name" value="manA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10309">
        <property type="entry name" value="MANNOSE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10309:SF4">
        <property type="entry name" value="MANNOSE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20511">
        <property type="entry name" value="PMI_typeI_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001480">
        <property type="entry name" value="Mannose-6-phosphate_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00714">
        <property type="entry name" value="MAN6PISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Phosphomannose isomerase type I catalytic" evidence="13">
        <location>
            <begin position="8"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001480-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF20511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ30556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="413" mass="44655" checksum="DD6356911749F5E8" modified="2011-01-11" version="1">MTPQSKKVFQLTGTCNNYEWGRKGRESLAARLCANTPGGGFEPADDQYYSEMWFGDYPDFPARVLDTGEPLRDLLNRDPDALLGPKVVRHLDAQLPYLPKILSIAKALPLQIHPDKALASRLHEEDPDAFSDPNHKPEIAVALGPFEVFAGFKPLDRIAPAFNLPALRHFIPDGTTAWSDETLREVVRRILLADDAAVERAASSLRDAAGVFGPGDAHVADLLPRLQAQYGPADPGTLVALLCMNYLVLDAGDALYIPADGIHAYLSGDIVECMARSNNVLNTGFCPPADRSNVDLFTRALTFAAHSDADVLLPAEPSPRGARGRTVVYPPPLREFDMLKTDLTAAAAGDDRSVEVIRAGEGPAVAIVTDGEGVLEADGNTFDVKAGYIWFIAPGVEAKWETKGTLQIFTTVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIJ4</accession>
    <name>E3QIJ4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fungal specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_05748</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094624.1">
        <property type="nucleotide sequence ID" value="XM_008096433.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIJ4"/>
    <dbReference type="GeneID" id="24411113"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05748"/>
    <dbReference type="eggNOG" id="ENOG502SHZM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008599_1_0_1"/>
    <dbReference type="OrthoDB" id="3362851at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000435">
        <property type="term" value="P:positive regulation of transcription from RNA polymerase II promoter by galactose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051127">
        <property type="entry name" value="Fungal_SecMet_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="28"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="137"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="139"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="164"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ30604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="741" mass="82343" checksum="503BC3AAADFACCCB" modified="2011-01-11" version="1">MFHSFDSRRSPSASAAAAPTLPRKVNRSCQECTRRKVKCDGGHPCASCQYYKVADSCEYRQRSRRHAVSRSTLEKTAEKLRDQSRVLQELFPDVSVDDLLGKSRAELLALLPRDSLSGTRPAVPQAGLLPAGVVSTAAPEEDGNEDEDDVPDDPTQLSESGEAANDRRWEESAHQPTTIRASDDINAVSLATDQHHSSYLGVTSVSAVLRAIFRLCPAAKEHTAQRVKTWNDAQNQSQLLPSLSPAGAGAGQNPLRERRCIVFYFDHVHPITPILNEDDFRRTLASGARHDGSWLALLNMVFTLGSVASGSDSLHLHYYKQARAHLDIDFLGSGNMESLQALCLLGGYYLHYRNSPNMAYAVLGAAHRVAIALGLHREPAPRSRIADERPVSDAERDTRVSRAETRRRTWWGLFCLDTWASMTLGRPTCGRWDGSTMDTLLPASLFPDDHVAASLRASCMFCHICDRIQHRFAQHARLSAQEALAFDRELREWHASLPEYLRDPANSPPRLAMAREFMRNRYLSVRLILSRCFLLYLAQSHGLRRGAASVSSIAEPSAEDMMLVDICRSVALEAIDAITLYWMPNRIHVWNSAWYLFQACMVPLLSIAIETRHRHSSCQQERPAVRPIPSLATAGMPPVAPLATWCAGLTKALEVFAEMRPWMRTSDYTPEIVAALYEAVTAEIEEPGAAVGPATRTPSATTDGSMDLFEWCDEQLAELDWGTYLGVGGEDGMHQRMFAFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIW2</accession>
    <name>E3QIW2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">WSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_05944</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094820.1">
        <property type="nucleotide sequence ID" value="XM_008096629.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIW2"/>
    <dbReference type="STRING" id="645133.E3QIW2"/>
    <dbReference type="GeneID" id="24411309"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05944"/>
    <dbReference type="eggNOG" id="ENOG502T08T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1015685_0_0_1"/>
    <dbReference type="OrthoDB" id="4826557at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178508" description="WSC domain-containing protein" evidence="2">
        <location>
            <begin position="17"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ30800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="274" mass="28491" checksum="B6185EB66A14D67C" modified="2011-01-11" version="1">MHVLCFTFCLSGPCGGSSIPRATFAVAPFVSSKHQIPAHHAAHLLSDACTEHNTTGWLTTYLLGNAIVLTEVSSAPPSSGTAAVVSQPIPTATEAGSGSGSGTSSGTSSRSPASTATSSAYISPPTGVRPASTDNGCPNINQTSYTPADANGDSVKVSSNSALIFRQLCEVNYPSGAEYGNPNLYDIFKVYVPNFRECMDLCAAYNQAYIGNLASGKMASGGYCRSVAMVKLPGEYCYLKNGTGETSKMDTQGHPKDFISAISPDVVISRSRMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJK7</accession>
    <name>E3QJK7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase C13 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_06189</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C13 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ31045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095065.1">
        <property type="nucleotide sequence ID" value="XM_008096874.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJK7"/>
    <dbReference type="STRING" id="645133.E3QJK7"/>
    <dbReference type="MEROPS" id="C13.005"/>
    <dbReference type="GeneID" id="24411554"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06189"/>
    <dbReference type="eggNOG" id="KOG1349">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044656_2_2_1"/>
    <dbReference type="OrthoDB" id="192611at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="PHI-base" id="PHI:6827"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042765">
        <property type="term" value="C:GPI-anchor transamidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003923">
        <property type="term" value="F:GPI-anchor transamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016255">
        <property type="term" value="P:attachment of GPI anchor to protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1460:FF:000003">
        <property type="entry name" value="GPI-anchor transamidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028361">
        <property type="entry name" value="GPI_transamidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001096">
        <property type="entry name" value="Peptidase_C13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48067">
        <property type="entry name" value="GPI-ANCHOR TRANSAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48067:SF1">
        <property type="entry name" value="GPI-ANCHOR TRANSAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01650">
        <property type="entry name" value="Peptidase_C13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500138">
        <property type="entry name" value="GPI8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019663">
        <property type="entry name" value="Legumain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00776">
        <property type="entry name" value="HEMOGLOBNASE"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5028234105" evidence="8">
        <location>
            <begin position="25"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="396"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="306"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="406"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR019663-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ31045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="415" mass="46615" checksum="FF5DE665EED48A47" modified="2011-01-11" version="1">MKLSRLLQLPVMLAAATLAPVVLAEHTSNWAVLVCTSRFWFNYRHLANVLSIYRTVKRLGIPDSQIILMLPDDMACNPRNAFPGTVYSNSDRAVDLYGDNIEVDYRGYEVTVENFIRLLTDRVGDEMPRSKRLLTDDRSNILVYMTGHGGNEFLKFQDAEEIGAFDLADAFEQMWEKKRYHEILFMIDTCQANTMYSKLYSPNIIATGSSELDQSSYSHHADNDVGVAVIDRYTYYNLEFLESQVQDLSSKKTVGELFDSYTYEKIHSHAGVRYDLFPGGADAARSRRITDFFGNVQNVEVDGAKNMALDEELLELSQKISALKRRAEEADAAAKNASLADKAKVQTPSAQVQAKRVKMAKPLTNDNWWEKKIVGATALAGCALLWALGSYLETPKAEEETKTTTGQNDHITVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QK17</accession>
    <name>E3QK17_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_06349</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697353">
        <property type="protein sequence ID" value="EFQ31205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095225.1">
        <property type="nucleotide sequence ID" value="XM_008097034.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QK17"/>
    <dbReference type="GeneID" id="24411714"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06349"/>
    <dbReference type="eggNOG" id="ENOG502RND2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2346593_0_0_1"/>
    <dbReference type="OrthoDB" id="4847285at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ31205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="97" mass="11276" checksum="47E6EDF4B0203088" modified="2011-01-11" version="1">MLDPISGWAIGITAVMLAIYGPYTYWISHGPTWDEWREREEAADRRRLREVIRDENRAADAAMLRQLTERAAELKARKRMQVEEKAGSKDQSEKKTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QK39</accession>
    <name>E3QK39_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Extracellular membrane protein CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_06371</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697354">
        <property type="protein sequence ID" value="EFQ31227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095247.1">
        <property type="nucleotide sequence ID" value="XM_008097056.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QK39"/>
    <dbReference type="GeneID" id="24411736"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06371"/>
    <dbReference type="eggNOG" id="ENOG502RJUX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060171_0_0_1"/>
    <dbReference type="OrthoDB" id="3630276at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179811" description="Extracellular membrane protein CFEM domain-containing protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="201"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ31227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="289" mass="30646" checksum="914176379B24C7DB" modified="2011-01-11" version="1">MRSSHSASAALIALLSATAISALSPAKLHCLRSRSLELARLAGCGEPGSVAHCIEMLPDDLRQTDLERCYIHAGCDLPEAIIESQRTLDGCGNDEKAPAELRKRHMPVLARQTTAAATTATEAVNTATSTGTDTGSLLTCSTTTTKSTTLCPVVSTGVRKGMTLNEGCYPTQLVFATCAAGLRCTDDLSGNPSCLKLDNTVYPGGIAVAIFFAVAVTLSFGWLTFLCCRERKHKKRAAARAEAASIARQPAKAPTVRVQNTDSQPLVEHGHPAAEYHDAHGPFSDQHRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKK9</accession>
    <name>E3QKK9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_06541</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697355">
        <property type="protein sequence ID" value="EFQ31397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095417.1">
        <property type="nucleotide sequence ID" value="XM_008097226.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKK9"/>
    <dbReference type="GeneID" id="24411906"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06541"/>
    <dbReference type="HOGENOM" id="CLU_3068566_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="53" mass="5789" checksum="B752CFD1661CD97E" modified="2011-01-11" version="1">MTEHSSPFPQGAFDGIGISYHLWIKTVGSEPHVTPGRPNRGNIGMNMPRPLAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLP7</accession>
    <name>E3QLP7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_06760</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697357">
        <property type="protein sequence ID" value="EFQ31785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095805.1">
        <property type="nucleotide sequence ID" value="XM_008097614.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLP7"/>
    <dbReference type="STRING" id="645133.E3QLP7"/>
    <dbReference type="GeneID" id="24412125"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06760"/>
    <dbReference type="eggNOG" id="ENOG502SK1Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064110_0_0_1"/>
    <dbReference type="OrthoDB" id="5421757at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ31785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="342" mass="39653" checksum="F689B4069BFE227D" modified="2011-01-11" version="1">MAPKIKAVKSKSTPKRSPGTPPAPFKKPAEVLQPLLETLSPKHVYITHIDSKPTDFKKKIFLVPVGMNLVVAALFVLRMYYILPYYFKFVQSAMGYPNETTFPTGDSTWGQLLWEVVKRGASLTLDFMLFVFVWPWPVEFVFGRSYGNPVSWRWKVGFREKEIYVRRSREWDQQLGDIFKEKEKNEALQQIIRQACSPLLLQEKTGYLTMTGQWDLDWQAMIDAHTMVDRKDIALDAFRRLVLVHHEDYGWMSVEEEGVSAKEDDRRRQVFQFRDALAAIGKENLFFRWIEIVQFESSQPGGFGPEKQVEVAKQIRDLFQEQGVDFDQVWHEAVGTDGLAGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLT4</accession>
    <name>E3QLT4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA recognition domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_06797</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697357">
        <property type="protein sequence ID" value="EFQ31822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095842.1">
        <property type="nucleotide sequence ID" value="XM_008097651.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLT4"/>
    <dbReference type="STRING" id="645133.E3QLT4"/>
    <dbReference type="GeneID" id="24412162"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06797"/>
    <dbReference type="eggNOG" id="KOG0118">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026447_0_1_1"/>
    <dbReference type="OrthoDB" id="1049195at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000145">
        <property type="entry name" value="Putative RNP domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000232">
        <property type="entry name" value="RNA-binding domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000280">
        <property type="entry name" value="RNA-binding domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003:SF3">
        <property type="entry name" value="FI21236P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="46"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="167"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="340"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="303"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="303"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ31822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="441" mass="45909" checksum="D4453FD580BE7DB3" modified="2011-01-11" version="1">MTGTGAPSGGSGTGYGGAPPHRSYEERAAAREQMMSNIRETSQQDRRVYVGNLSYDVKWHHLKDFMRQAGEVLFADVLLLPNGMSKGCGIVEYATRDQAQNAVATLSNQNLMGRLVYVREDREAEPRFIGATANRGGFGGGGMNPGGFATGGGGGGIGGYNPGGGSRQIYIANLPYTVGWQDLKDLFRQAARNGVVIRADVHLGPDGRPKGSGIVVFENPDDARNAIQQFNGYDWQGRLLEVREDRFAGAGGPMGFGGRGGFGGGGMRGGFGGGYGRGGFGGGRGGFGGGGYGRGGFGGGPGVGGIGGPGAPGGFDASNAPSVPPNPFTDYATAGTDRSETIYVRNLPWSTSNEDLVELFTTIGKVEQAEIQYEPSGRSRGTGVVRFDSAETAETAIAKFQGYQYGGRPLGLSFVRYLNAAGGGDMMETDAHAGLTQDQIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QM17</accession>
    <name>E3QM17_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_07049</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095925.1">
        <property type="nucleotide sequence ID" value="XM_008097734.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QM17"/>
    <dbReference type="GeneID" id="24412414"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07049"/>
    <dbReference type="eggNOG" id="KOG2504">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_1_1_1"/>
    <dbReference type="OrthoDB" id="6509908at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17352">
        <property type="entry name" value="MFS_MCT_SLC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF234">
        <property type="entry name" value="MFS-TYPE TRANSPORTER DBAD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="133"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="190"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="225"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="264"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="329"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="355"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="392"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="425"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="5">
        <location>
            <begin position="264"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ31905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="455" mass="48325" checksum="26F38187CAC17EBE" modified="2011-01-11" version="1">MTARISFAGEKSGSVPGFRSSTPSETSLTPAAVDPESRAATDTAQRPLKPSAPGPVPDGGLEAWFQVLGSWVILAQTWGLVNAFGVYQTYYERTLNDVAPSAISWIGSLQGALLMMVGPISGPLYDAGYFRELLWAGMFLILLGMFMTSLCTAYWQVLLAQGVCVGVGCGLVFLPSTAILSQYFDKRRALVIGIAATGSPIAGMTFPILFGHLEPKIGFGWSTRIIAFILLGLSIIPAVTMHTRLPPSGHKRSLIDQTALRDPAFMLVVVGSFIGFLAMYVPYFYIQLFAVNHDIGPSDFSAYFVTLLSAGSIPGRVIPNYLADKVGALYMHIAVAAGSAVLMFAWLGIRNMAGLIVFAILYGLFSGGLVSISPTVVVSLSPDLSRVGTRMGMMNFIAGIAILVGTPIAGAILGDYGEVAWQSMIGYGAAALTVGSMCLTLAKIFQLKTARSLKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QM91</accession>
    <name>E3QM91_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">High-affinity methionine permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_07123</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095999.1">
        <property type="nucleotide sequence ID" value="XM_008097808.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QM91"/>
    <dbReference type="STRING" id="645133.E3QM91"/>
    <dbReference type="GeneID" id="24412488"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07123"/>
    <dbReference type="eggNOG" id="KOG1287">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013661_1_1_1"/>
    <dbReference type="OrthoDB" id="5982228at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050598">
        <property type="entry name" value="AminoAcid_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785:SF382">
        <property type="entry name" value="LOW-AFFINITY METHIONINE PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="266"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="299"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="359"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="439"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="471"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="529"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="562"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ31979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="685" mass="75223" checksum="6DBE492906C7EE5F" modified="2011-01-11" version="1">MNDFPSSAGFYQEEPRGIEDSSTHSDIDSVIDNIGSGIVTHAPKEGFRLGYFDVSCLVINRMIGTGIFMSPKRVMEGTGSVGASLLLWFAGIIYCLCGTHVYIEYGMNVPRYIIDGVESSVPRSGGDLVYLQYVFRKPAYRKNTILLSTCIFGISFIVLGNMAGNCIHFALRVLEAAGFDEPQNGPVRGIALAAATFSCSVHALSRRFGILLNNTLAMVKIMIMLLIVVAAIVVGAGGFPATENVIADNTSPKNSFRDASKEANGYAQAFLAIIFTFSGFEQPNYVLGEISRPRKKFPIAMRAGVGVVVVLYLTVNICYLVVVPKDEQAQYNVAQRFFQLTFGSLGSADAANNGTGFRIFNALLAVSSMGNIIVMTYTAARVKQEIAKEGILPWPKFFAQNTDMSIGRLIRWFQKKGWFVSLHRVRWLSPEHHTEKTPVGALVLHFVSCVILIFATYGIQPTTAYTLLTSLSAYVINAFIGTFLGLGILILRFRGPPRTVAEDDASTNGRDSQPLTWAEMTGKRFRPSLSIFCALVYMCGGLFPVITNWVPPGTLAATVKPWYLVPTVSWIIIGIGIAWFLGFVLVARYIERKDHSEFVVEKRPEFEPAEGSSRSPEAVGTGVDLIQVHETVYLSWVGKEALRSRRPVFENTKHADGAVREVAMSPYAGTDFAALMSNQTAPDRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>E3QML3</accession>
    <name>E3QML3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 16">E3 ubiquitin-protein ligase listerin</fullName>
            <ecNumber evidence="5 16">2.3.2.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">RING-type E3 ubiquitin transferase listerin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">GLRG_07245</name>
    </gene>
    <organism evidence="19">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">E3 ubiquitin-protein ligase component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. Mediates ubiquitination of proteins derived from mRNAs lacking stop codons (non-stop proteins) and other translation arrest products induced by poly-lysine sequences and tandem rare codons. Ubiquitination leads to CDC48 recruitment for extraction and degradation of the incomplete translation product. May indirectly play a role in chromatin function and transcription.</text>
    </comment>
    <comment type="function">
        <text evidence="16">E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 20">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 16">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="16">Component of the ribosome quality control complex (RQC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 16">Belongs to the LTN1 family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="5 16"/>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096121.1">
        <property type="nucleotide sequence ID" value="XM_008097930.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QML3"/>
    <dbReference type="GeneID" id="24412610"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07245"/>
    <dbReference type="eggNOG" id="KOG0803">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000471_0_0_1"/>
    <dbReference type="OrthoDB" id="6108at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990112">
        <property type="term" value="C:RQC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072344">
        <property type="term" value="P:rescue of stalled ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990116">
        <property type="term" value="P:ribosome-associated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16491">
        <property type="entry name" value="RING-CH-C4HC3_LTN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000038">
        <property type="entry name" value="E3 ubiquitin-protein ligase listerin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039795">
        <property type="entry name" value="LTN1/Rkr1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054477">
        <property type="entry name" value="LTN1_E3_ligase_6th"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054476">
        <property type="entry name" value="Ltn1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054478">
        <property type="entry name" value="LTN1_UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039804">
        <property type="entry name" value="RING-CH-C4HC3_LTN1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057030">
        <property type="entry name" value="TPR_Rkr-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12389:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE LISTERIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12389">
        <property type="entry name" value="ZINC FINGER PROTEIN 294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22958">
        <property type="entry name" value="Ltn1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22999">
        <property type="entry name" value="LTN1_E3_ligase_6th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23280">
        <property type="entry name" value="TPR_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23009">
        <property type="entry name" value="UBC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01197">
        <property type="entry name" value="FANCL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0677">Repeat</keyword>
    <keyword evidence="8 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="12 16" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="13 16" id="KW-0862">Zinc</keyword>
    <keyword evidence="11 15 16" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="17">
        <location>
            <begin position="1565"/>
            <end position="1611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00055150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU367090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EFQ32101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1627" mass="179056" checksum="E052036FB1BF3B49" modified="2011-01-11" version="1">MSRAFGKGGRSSGARGFASPASGFGGFSSAGSGLSYLAEPPDLTSISDANVVVSFKNTLKKDATTKAKALEELLAYVQAHPFEKDGGVEEAVLEAWVQIYPRISIDNSRRVRELSHTLQFELMKSARKRMEKNVPKVVGTWLAGLYDKDRVVSRAANDSLSSFLNSPEKAVLFWKKCQSQILTYAKDAIQETKDTLSDERSTTPDDADAKYLRVVGASISLVLSLLQKLEPADIQKEEEVYDAFLAEEKVWKSVVMGDASVRRVACQLLWACLDKRPESVSSQISRLKKSFIAEGLKSSQTGSAVEYVRVLTKLTSKFPEVWTSSSEKKTPITRLNGFLVKGSHSSPAKYWEHLEDLIKAIPADHFTTEASADALKSMRTGITSREEPRMNATLAWTCYVHTTKHFLQNFPSGGPRATLVQEHLFPILDHFLFPTPETSAWEIGGAGQLIVLGEVYKVAADLSSPDLLQAASEKLEALASAFCTRISNSLPEVSKDYEKSQEAVSAEGKRWFTLVSQVQKTGQSPTSLLMGPSKSIITSSLNLLANRKLKPYGAAGVIYSVGENAPQVWDDVDAAQALEQFLATQGRDHMAVLVDSRSAADLLNCVNVMGTLKGHETAYATIWKTWIDALLDLSEEKLAARGIERLIANQQASKLSKSHEKLQIFLEAKCSGTARGESDSWSLFEAALGNDALTESTAKQLLVNSISALSQDKQHSLQALRALEILANNKPGLLSQDESTHMAVVTELLGLAELNDRAVSSRAISLRALLEQPTDGTSPVVAIIQRNLEEAGPQSLGIETLVQQALQAVKEGSISTEDLFPSTNVWMQQLSNFLQGSLNPSLSITSGLGGAHFLVQPTEQEQRIRVRRDRDGYSVPARMASYTAKLLSSDISVSALPESFQAELLYLLCVSVQMVSDQITLMDENKLFLDLNLGDTLATAESFVSSTRVTINAIADDAKGWRDGSETGSTKLINSLIAIMTQETKELTVLGVYSSRALSELIQALTEKHGFPAAGDEKVNQLATFKATPPTVLAATAVLAGFGESLESSKAVNMLCNRLISDIAGASVEPGKADKTLQVLVLLNACLQVYEVGETPVANNRIVFAVRQITSWMDDTLNLTPALSAEICRVLQRLLPSMKDVYGSYWEKTIEFSTALWAKASDDRLDDSLPYIHASLKLMTTLETLSEPNDDLVESLKEFAETKSLSLIELLKLDREKSTQPLEIVDAIICRQVNKISLKHIGDLSDLYGLIATDSRSIQTAAFNLLHYALPARQEELSVSVLLDKTDARLPDELLSLLLDAPTLERYPDEVLAQFPLAIRSYLLSWHLIFDAFSTASLKVRNDYTEHLKTENYLAQLLDFTFDVLGHSAAHPLNLERENLKTQHITSYDVSLADAESDERNLHWLLVHLYYLTLKYTPGIFKTWYLNCRSKQTRIAVEGWMTRYFSPIIISDALDEVSVWAATQEPPVDDEKELVVKVSKTGKEITAGYEVDESMASIAIKVPASYPIEGVSVVGINRVAVNERKWQSWLLTTQGVITFSNGSIVDGLSAFRRNIVGALKGQSECAICYSIISTDKKMPDKRCQTCKNLFHRTCLYKWFQSSNQNTCPLCRNPIDYLGSDTKARRGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMN9</accession>
    <name>E3QMN9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Methyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_07271</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096147.1">
        <property type="nucleotide sequence ID" value="XM_008097956.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMN9"/>
    <dbReference type="STRING" id="645133.E3QMN9"/>
    <dbReference type="GeneID" id="24412636"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07271"/>
    <dbReference type="eggNOG" id="KOG3010">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049344_1_2_1"/>
    <dbReference type="OrthoDB" id="10027013at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051052">
        <property type="entry name" value="Diverse_substrate_MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44942">
        <property type="entry name" value="METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44942:SF4">
        <property type="entry name" value="METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="4">
        <location>
            <begin position="43"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ32127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="308" mass="34056" checksum="66634D2745E4D4F4" modified="2011-01-11" version="1">MSVFARSTFSAAGYAAFRPSYPASLFKMLLAYHKPSSANGTALDLGCGHGVIARELAPHFGRVMAVDPSAGMVKQASESTRDPKITFRQGSAEDLSFVGDGTVDLAIAGQSAHWFDYKRAWPELGRVVCGGGTLAFWGYKDNILVGFPAVNEILEHFLYGEGEAAPGSGWETMERYWEKPGRQMLRDNLEAVVPPASEWTAVRRIVYNPDRRMAQVGTGPEAEAAWQRKKLKLGEFEGYVHTFSAYIGWRDAHPEVKSRAEGGEGDIADLLFDRLLEAVPEWKAKGDKWREVEVEAVWGTVVILAKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMY5</accession>
    <name>E3QMY5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07367</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697360">
        <property type="protein sequence ID" value="EFQ32223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096243.1">
        <property type="nucleotide sequence ID" value="XM_008098052.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMY5"/>
    <dbReference type="GeneID" id="24412732"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07367"/>
    <dbReference type="HOGENOM" id="CLU_2277294_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="102" mass="11135" checksum="1D0E41A4892DFB11" modified="2011-01-11" version="1">MRIRLQKQSPIGGHRPPQEPPEAAPAMIIIWCIRRRSTSFFSMPTQLATTSASTASRARLPFAPVHRDRSTASLPPFPAALRPVPSVLVPGPRTSWATRAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNM8</accession>
    <name>E3QNM8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">PHD-finger domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_07785</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EFQ32515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_008098344.1"/>
    </dbReference>
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    <dbReference type="STRING" id="645133.E3QNM8"/>
    <dbReference type="GeneID" id="24413150"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07785"/>
    <dbReference type="eggNOG" id="KOG4323">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035251_1_0_1"/>
    <dbReference type="OrthoDB" id="5863171at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="7">
        <location>
            <begin position="227"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="147"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="387"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="279"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="14"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="47"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="82"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="407"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="439"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="468"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ32515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="535" mass="59233" checksum="58498177F31922F1" modified="2011-01-11" version="1">MLEPLRPTAMALTSERRDEIRPVENESRDEMEATPSATTIWHAARDAQTTATSAALTQPSPTPAEPQRAAVSGTDKAEEPTSAPSSYRRQFSPATSRYVLGRLHQARDSKPSPPALIAAADERHPATPAAAEEAPLHCPVDLSSLPRTLHLPDATPAASPSTTILDPPPPPAGTKRKHAADHEGGGVGGPRRPASLAPAYPEPEILRRPMSRPPTKRKRTRDDGNGNPMCARCKRTSWTDANLIVACASCGEAWHQLCHDQPATLVPGDDDGGFRCATCEDEEKEQAEYQRQIARYREAKQEQAEWRRRQNDVERRREKRLAALPVFPDSRIIGFEGGDASPEERREYFENLKKSDLVNLLIFSNDIYPGLLVDLLVSVSKRHPDLPIFGSPDWVQPKAPRREPQRQRQRQRQGNHARLKVPKQRSKTGGVRKILKTTPVAPAAAPAAAGVAGVDGEQQQQQQHQQQEDDEYDDDGDDDDDDALPESWPKAGHGLYSKLKPEREDPLLFDDKDEEAFSHFMVDEQGRQVVELLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPE9</accession>
    <name>E3QPE9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Endoribonuclease L-PSP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_07881</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697364">
        <property type="protein sequence ID" value="EFQ32737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096757.1">
        <property type="nucleotide sequence ID" value="XM_008098566.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPE9"/>
    <dbReference type="STRING" id="645133.E3QPE9"/>
    <dbReference type="GeneID" id="24413246"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07881"/>
    <dbReference type="eggNOG" id="ENOG502S1PE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100715_1_1_1"/>
    <dbReference type="OrthoDB" id="309640at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06152">
        <property type="entry name" value="YjgF_YER057c_UK114_like_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="entry name" value="RutC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43857">
        <property type="entry name" value="BLR7761 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43857:SF1">
        <property type="entry name" value="YJGH FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="YjgF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ32737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="146" mass="16301" checksum="C1EAF833492B6079" modified="2011-01-11" version="1">MSGLKYFSYEEYGVTLRKEMHYSQAVRVGENIEISGQGGWDPKTGDITDDLLKEIDQAFENVDLTLKDAGGKGWSQVFRIRLYAVDEAWTQEGIGRMVDNIKKWTPNHAPILTGVGVTKLGQPGMRVEVEVSAYDPCEPSKTSETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQ25</accession>
    <name>E3QQ25_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">Dolichyl-phosphate-mannose--protein mannosyltransferase</fullName>
            <ecNumber evidence="4 14">2.4.1.109</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">GLRG_08107</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17377"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:13546"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137321"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 14">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-threonyl-[protein] = 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53396"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:13547"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137323"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Endoplasmic reticulum membrane</location>
            <topology evidence="1 14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the glycosyltransferase 39 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.109" evidence="4 14"/>
    <dbReference type="EMBL" id="GG697366">
        <property type="protein sequence ID" value="EFQ32963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096983.1">
        <property type="nucleotide sequence ID" value="XM_008098792.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQ25"/>
    <dbReference type="STRING" id="645133.E3QQ25"/>
    <dbReference type="GeneID" id="24413472"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08107"/>
    <dbReference type="eggNOG" id="KOG3359">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008438_5_0_1"/>
    <dbReference type="OrthoDB" id="292747at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004169">
        <property type="term" value="F:dolichyl-phosphate-mannose-protein mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd23284">
        <property type="entry name" value="beta-trefoil_MIR_PMT2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.80.10.50:FF:000012">
        <property type="entry name" value="Protein O-mannosyl-transferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003342">
        <property type="entry name" value="ArnT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036300">
        <property type="entry name" value="MIR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016093">
        <property type="entry name" value="MIR_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027005">
        <property type="entry name" value="PMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032421">
        <property type="entry name" value="PMT_4TMC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050">
        <property type="entry name" value="DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050:SF46">
        <property type="entry name" value="PROTEIN O-MANNOSYL-TRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02815">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02366">
        <property type="entry name" value="PMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16192">
        <property type="entry name" value="PMT_4TMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00472">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82109">
        <property type="entry name" value="MIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50919">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 14 16" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 14 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="224"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="278"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="598"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="640"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="666"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="697"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="15">
        <location>
            <begin position="332"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="15">
        <location>
            <begin position="398"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="15">
        <location>
            <begin position="462"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00045085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU367007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EFQ32963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="738" mass="83804" checksum="BC6D7CB6EA043B82" modified="2011-01-11" version="1">MAVEKPIVASGADVGDGVRRRAVPQGQSVPLTAAPEVDDKKKLAKKGPSFLDQYEVVIAPIVFTAVAIFTRLWRIGLSNIVTWDEAHFGKFGSHYIKHEYYFDVHPPLGKMLVGLSGVLAGYNGSFEFKSGEKYPEDVDYTFMRAFNALFGILCIPMAYFTARELNLRRPAVWLVTLMVLCENSYTTISRFILLDSMLLFGTVATVLCWAKFHNQRHNAFEPEWFFWLFMTGLSIGCVCSVKLVGLFVTALVGLYTIEDLWNKFGDTKMPVTTLGAHVVTRVVGLIIVPFLVYMLSFALHFAILDQTGPGDAQMSSLFQANLKGTEVGKNSPLEIAYGSRATIKNMGYGGGLLHSHIQTYPEGSTQQQVTCYHHKDANNDWFFYPNRHDEDYNPEAEPRFIADGSTIRLIHAQTGRNLHSHEIAAPITKADKEVSCYGNLTIGDDKDHWQVEVVRDVASRDRSRIRTLTTAFRLKHPVLGCYLRAGNVNLPQWGFKQIEVTCTKKNNPKDSYTHWNVEAHTNDKLPPGDPGSYKSPFLHDFIHLNVAMMTSNNALVPDPDKQDDLASHWWQWPILNVGLRMCGWDDNIVKYFLLGNPLVYWGSTAGLGIFALVVVWYIVRWQRGYNDLNTKEVDQIHYAGLYPVAGWFLHYLPFVVMARVTYVHHYYPALYFAILTFGFLADWFLRNRNHIVQYTVYGVLYAAIIGLYILFSPICFGMTGPNKQYSYLKWFDSWRISD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQ99</accession>
    <name>E3QQ99_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Calcium uniporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">GLRG_08181</name>
    </gene>
    <organism evidence="21">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Highly selective calcium channel localized to the inner mitochondrial membrane, which mediates calcium uptake into the mitochondrial matrix. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates ATP production, cytoplasmic calcium signals and activation of cell death pathways. Sufficient to operate as a pore-forming channel without the need of calcium-sensor or auxiliary subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="17">Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>Ca(2+)(in) = Ca(2+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29671"/>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="15">Homotetramer, assembles in a dimer or dimers configuration with two interfaces.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 17">Mitochondrion inner membrane</location>
            <topology evidence="1 17">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 17">Belongs to the MCU (TC 1.A.77) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697367">
        <property type="protein sequence ID" value="EFQ33037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097057.1">
        <property type="nucleotide sequence ID" value="XM_008098866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQ99"/>
    <dbReference type="STRING" id="645133.E3QQ99"/>
    <dbReference type="GeneID" id="24413546"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08181"/>
    <dbReference type="eggNOG" id="KOG2966">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035826_1_1_1"/>
    <dbReference type="OrthoDB" id="278338at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990246">
        <property type="term" value="C:uniplex complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005262">
        <property type="term" value="F:calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015292">
        <property type="term" value="F:uniporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036444">
        <property type="term" value="P:calcium import into the mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051560">
        <property type="term" value="P:mitochondrial calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006769">
        <property type="entry name" value="MCU_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039055">
        <property type="entry name" value="MCU_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13462">
        <property type="entry name" value="CALCIUM UNIPORTER PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13462:SF10">
        <property type="entry name" value="CALCIUM UNIPORTER PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04678">
        <property type="entry name" value="MCU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 17" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 17" id="KW-0107">Calcium channel</keyword>
    <keyword evidence="4 17" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="13 17" id="KW-0407">Ion channel</keyword>
    <keyword evidence="10 17" id="KW-0406">Ion transport</keyword>
    <keyword evidence="12 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="11 17" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7 17" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 17" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="317"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="349"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="Calcium uniporter protein C-terminal" evidence="19">
        <location>
            <begin position="285"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="56"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="196"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="434"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="56"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="196"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="227"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="439"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="461"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00036634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00044966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00045938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU367035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF04678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EFQ33037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="485" mass="56058" checksum="A83E402F11593DEA" modified="2011-01-11" version="1">MSYAFRRVCLQLPASFSPKYGPMRQAFRPAGLGTGTKASVTGRAFRLSAIWRDDADDAKAKKTSQRDMDKEEDKEKFERDELIALRKQEERPWHRAGHEVDQRESSKDPTNGDKTRGRLLTTPTRLLKLILPLPFHAEQSRINQTPKKDEEKADIAPLALLVHPQQPLSYLERLLQAEIPPIDDGRRERIPKIYFRAEADHQESKPDRRSSQKQEGNVASYSGLGHEGPKRDHDDKNWVRWSGSTEVGDFIRDAARGREFSIGIEGYDQELRVAVPSFNDRTYYMRIRLRRMSRRVEELAKIKQECDYLAHRGAHRLAQGGFALLSGWWGVVYYVTFHTDFGWDLVEPVTYLAGLTTIMGGYLWFLYISKDLSYKAALNITVSKRQSALYHERGFDQAAWDALVHEANSLRREIRFVATEYDVDWDETKDLGGEEVQEVLDKEKKGSRRRGEDDDAEEEERVEHQRKDDKKTPQKSEEGIDSNKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQA7</accession>
    <name>E3QQA7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08189</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697367">
        <property type="protein sequence ID" value="EFQ33045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097065.1">
        <property type="nucleotide sequence ID" value="XM_008098874.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQA7"/>
    <dbReference type="GeneID" id="24413554"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08189"/>
    <dbReference type="eggNOG" id="ENOG502T5G8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1023115_0_0_1"/>
    <dbReference type="OrthoDB" id="4850950at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180707" evidence="1">
        <location>
            <begin position="21"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ33045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="272" mass="29907" checksum="AA67B6049B7EE641" modified="2011-01-11" version="1">MKSTLLGFAALAALLAPAVAIPLFPTNDTTSYDTVGLKGGFDPAKIMEKDCLRWCPHIVPGLHAYKQPATFDCRLRCRSEAFYRASRQVSSQAAKAAINKTRAEGFSREPVVPLELGLFLKKHRLLNTTGIESRSEGDMASQVAVGGDEVKIDPKKPKGNPCAWPTEWDNSAESQREMHTCLASCPVGSFFGVCLHPCFLEIMERRCGEKTAEQYYKPQGAEHWAGIRRQWGPNLPGIPPEKLPKLLVDYPPITHNFPGGGNAIPGDEYLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQB7</accession>
    <name>E3QQB7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">WD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_08199</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat MET30/SCONB/SCON-2 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697367">
        <property type="protein sequence ID" value="EFQ33055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097075.1">
        <property type="nucleotide sequence ID" value="XM_008098884.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQB7"/>
    <dbReference type="STRING" id="645133.E3QQB7"/>
    <dbReference type="GeneID" id="24413564"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08199"/>
    <dbReference type="eggNOG" id="KOG0274">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0281">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_103_0_1"/>
    <dbReference type="OrthoDB" id="19711at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050995">
        <property type="entry name" value="WD-F-box_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14604:SF4">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14604">
        <property type="entry name" value="WD40 REPEAT PF20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="F-box" evidence="6">
        <location>
            <begin position="92"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="348"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="389"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="512"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="552"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="232"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="896"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="24"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="899"/>
            <end position="917"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ33055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="993" mass="107722" checksum="1BD6A9C10B9C45AB" modified="2011-01-11" version="1">MAAFVSQDPDEGYSEDPLNPGFGASQDVSSPSSSAAAAAAARPPADLPAWLVRHIPSLPVAARTELAIALLDNLPTSAVVQIVQRLHPRLYIDFVHYLPPEVCLKILAYLDPISLVNVAKACRAWHELALDRKLWEKLYHLEGWKALYPEIRLWEQKVNEGLNLSASSLHRVRSSEDGHTYKKRAISEDNDLEMTDAGVASSTGVREDSVNSTSSVFGTSIFGSPASSFTGFPRNSAAPQAGDMDVDRSSSGPNSRSGERGFGVDSKGKGTASPMLRAALVKEESLPPMIPADAPGGIARSTLWSWDAPSARYRVNWKYLYTMRRRLEQNWELGKFSNFQLPHPDHLNEGHQECIYSLQYDSEYLVSGSRDKTIRIWSMHTRRLLRKPLEGHTGSVLCLQFDSDPEEDLIVSGSSDSDVILWRFSTGQIIQRLKNAHTESVLNVKFDKRILVTCSKDKSIKIFNRRPLKYGDAGYGDVDVVFSAPTHLRNYGYANPLDELPVKPPYTMIGVLEGHGAAVNAVQICDNEVVSASGDRNIKVWDWAKQVCIRTVVGHGKGIACVQYDGRRIVSGSSDNEVKVFDRTTGLEVASLRAHTNLVRTVQAGFGDLPYSAAEDRAEARRIDEQYFKAIEDGIITPFSDHNRSRRAQPRNAGSRRPEDITAYGAALPPGGGGGKYARIVSGSYDQSIIIWRRDKEGVWKDTQHLRQEDAAAAAQAQARATSQAPAEVMPAEAMPTETVPTEAVPAAPNQSALRHLIASRAARQGLPAASARAAAGAAVLADAAPAFMHLIDTVVPQGPTQLRQALHNHPNMVAAYRAHIQAAIGREPNSRIRDDLRGVLNAALLEAHINQSRGLGGNREGPTIVPPALPSLAPAAAGTAAGTSSAANVPQVQGHLHIQGQGQPAQPTQPGAPIQAQATPVPVQGAQNAIVPDAVHHPHIANGDNGPARVFKLQYDARRIICCSQTTVIVGWDFCNNDPELEEVARFFGTVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQI6</accession>
    <name>E3QQI6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_08268</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <dbReference type="EMBL" id="GG697367">
        <property type="protein sequence ID" value="EFQ33124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097144.1">
        <property type="nucleotide sequence ID" value="XM_008098953.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQI6"/>
    <dbReference type="STRING" id="645133.E3QQI6"/>
    <dbReference type="GeneID" id="24413633"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08268"/>
    <dbReference type="eggNOG" id="ENOG502T3U6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_750075_0_0_1"/>
    <dbReference type="OrthoDB" id="433924at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="3">
        <location>
            <begin position="84"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="160"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ33124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="370" mass="40958" checksum="AD8277D71B390379" modified="2011-01-11" version="1">MPRGRCLAKLAEQADFPYDAIKKILAHSLDPDTALVTLTVLVKGAREDISEWDVQEHRPALLFDYWASFKGRTRQDVLGIGELYHPFKFLRHRRVRGQWQVLVQWLGYSTEGEDASWEPVIKMRTDGPGVLADYCGYVDDESTKAALLGPIALTDGTGDLVSANEDSKPSVRTPVPTKQTTKRKRGSLAEQSEPVGDKRRRSSRYDSTSAIKSPAPKPSASKRRQSHVPPDASIPPQMTPKSPTSTKTQEKLPVNATASVAPSPAPSQPQSRRKSSRAASVATPGAPAPQRLSPADVPRTMLWFMDDFTVGDMQKVCRFIDEHCTGKLRLPLYSGGDWDGKTASGRWEDVFMVSPLGRLGRYDNEDEKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQT6</accession>
    <name>E3QQT6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Integral membrane channel protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_08368</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697368">
        <property type="protein sequence ID" value="EFQ33224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097244.1">
        <property type="nucleotide sequence ID" value="XM_008099053.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQT6"/>
    <dbReference type="STRING" id="645133.E3QQT6"/>
    <dbReference type="GeneID" id="24413733"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08368"/>
    <dbReference type="eggNOG" id="ENOG502QU70">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003613_0_0_1"/>
    <dbReference type="OrthoDB" id="2373987at2759"/>
    <dbReference type="PHI-base" id="PHI:9111"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056337">
        <property type="entry name" value="LHD_YVC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052971">
        <property type="entry name" value="TRP_calcium_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056336">
        <property type="entry name" value="YVC1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35859:SF4">
        <property type="entry name" value="MEMBRANE CHANNEL PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G11300)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35859">
        <property type="entry name" value="NONSELECTIVE CATION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23190">
        <property type="entry name" value="LHD_TRPY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23317">
        <property type="entry name" value="YVC1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="337"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="369"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="393"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="436"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="467"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="502"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="533"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="583"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="domain" description="YVC1 N-terminal linker helical" evidence="3">
        <location>
            <begin position="102"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="Calcium channel YVC1-like C-terminal transmembrane" evidence="4">
        <location>
            <begin position="345"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="706"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="800"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1068"/>
            <end position="1163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="706"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="729"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="811"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="842"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="860"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1069"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1098"/>
            <end position="1110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1111"/>
            <end position="1123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1126"/>
            <end position="1141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ33224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1163" mass="130532" checksum="C0B67011FD3A29C0" modified="2011-01-11" version="1">MFSSLLRPKQSNRSRRVDRFHDRQSPSPGPAYRHYVGEPPRRATGDFTEGEDDQEEEDEEDDGSGHSGDDNEHVDDEDLSRRSMPVLPLFSSTYLDSLPIYSITHAIRVIVQARTETTLTWDQIRSPQVSQFLVKPMQQQIRTQQFNRATLYCLMANCLQFNKEGHMYPGNAGTSYTRALVCELLALKLLKEYNTRELIDALSYDFYPLQGLPGAQPASTPKADPRNKARLTASRTSTLEVAIRASAKHFLAHPLVVQQLEAIWNGAISFYSSADSLHREPPPSPTGIRPDARTPLLGGHNQKEGQQQSAPGRRSVILYDPRQASLFKLSRLRVPRYRFFLSTMSLLVLIGLFLAVLSQRSARISSLELIFWFWSAGFMLDELVGFNEQGFSLYIMSFWNAFDLGILLLLIVYYFMRVYGVFLVDAKHWNDSAYDVLAANAILLLPRIFSVLDHYQYFSQLLIAFRLMAVDLAAVCILILICCSGFFVFFTLADTNNDAGDIAFRIFQILMGFTPAAWEVWPGYNWLERGLMAFFLILCHFVIVTILITVLTNSFMKIASNAREEHQFLFAINTISMVKNDALFSYVAPGNIFAWLLMPMRYCMPLKQFVKLNRTIIKVTHFPLLFCIFLYEKYWLAPSMYEPTDLVENHHHHGRDRTISFADPASRPALFSPNIRVREESVAGYQKDHALEEVFRRGPGFATLRNQRRNERKKTQHAVRNWMDRNDEASASPQLSQWPTLDGSQGVRPDWLRRLSLSRELRTRRSRQMSDVRSAASDPADLISQPAIGSFFRGIAAATTAKDEENQQTDADGDDELVTNDEEEEEDIATNADDSRHGPVIHQTSIDDYFNTTPSTKRFVPPTSSSLGSSGRPSVSATPRSARRVPHSRTMSTNTILYAPQELRRPPSSSTHSPDPPPTRARVQNGRPAVVEPAVASGHRSPRRQTYVATTKPRPIMPPRDAAQTAPNRAGLVSVDQRPRPNPLRRLSSVDLSVLSDNIVPDDPNGGGISSSFQTQMAMALMKDARLGGAGRGTDSGDSNRMSKLVLARMKTLEESFADVAKELRELKTTSSSTAPTTRRNSSGEELQKMTSLMSAEATRHKDGGSERPKLGGRRTTGKRPASRKSLLDPKSERARGKGKEPALSSGDDSDSESMSPIKRSSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRG3</accession>
    <name>E3QRG3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08730</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697370">
        <property type="protein sequence ID" value="EFQ33451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097471.1">
        <property type="nucleotide sequence ID" value="XM_008099280.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRG3"/>
    <dbReference type="GeneID" id="24414095"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08730"/>
    <dbReference type="eggNOG" id="ENOG502RNJ9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1618887_0_0_1"/>
    <dbReference type="OrthoDB" id="5229017at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ33451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="170" mass="18576" checksum="CB7821F2B1FC6458" modified="2011-01-11" version="1">MYVSTREGGTSVFRSPSPKELHEMQWQIGTGGAGRLVKMEQVVPAAPPSQEADTSNGNDITDIDGSRDSPDSLCAPNSRERRPENRRRVWFTNIFGLETVLSLREPPDPKPVPLPEGCVTPHPIFARKFSLVADNQPLPPSLPHDMMPTADIKARRLLADAAVQGLMGPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRM7</accession>
    <name>E3QRM7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbon-nitrogen hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_08794</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697371">
        <property type="protein sequence ID" value="EFQ33515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097535.1">
        <property type="nucleotide sequence ID" value="XM_008099344.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRM7"/>
    <dbReference type="STRING" id="645133.E3QRM7"/>
    <dbReference type="GeneID" id="24414159"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08794"/>
    <dbReference type="eggNOG" id="KOG0806">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030130_2_0_1"/>
    <dbReference type="OrthoDB" id="412018at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07197">
        <property type="entry name" value="nitrilase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050345">
        <property type="entry name" value="Aliph_Amidase/BUP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43674:SF16">
        <property type="entry name" value="CARBON-NITROGEN FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G02350)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43674">
        <property type="entry name" value="NITRILASE C965.09-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="2">
        <location>
            <begin position="5"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ33515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="325" mass="35517" checksum="BC33D9969336F425" modified="2011-01-11" version="1">MADRFKIALIQMHPKVSEPETTPNKDAQAMFSSRVVAPEENFAKAESYIRSAASQGCSLAVLPEYHLTSWVPDHPKFVPSCAQSGVYLEKYQALARDLVISIVPGTIIELDGEEGDDDLNLLNVAYFIGPDGGVLGQYTKKNLWHNERPHLTKGPEPHGAFETPLGRAGILVCWDLAFPEAFRELVRDGARVIVCPAFWLADEYKREDGDEGAQVVNRDSERVFLENVMVARAFENTAAVVLVNAGGPVGGGGVEVREGGARVRYCGVSQVAMPLIGPQGKLGAEEAMEVVEVDLGLLDVAEGAYKVREDMKKEGWHYGYSIVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRT1</accession>
    <name>E3QRT1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GPI anchored protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_08848</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697371">
        <property type="protein sequence ID" value="EFQ33569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097589.1">
        <property type="nucleotide sequence ID" value="XM_008099398.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRT1"/>
    <dbReference type="STRING" id="645133.E3QRT1"/>
    <dbReference type="GeneID" id="24414213"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08848"/>
    <dbReference type="HOGENOM" id="CLU_1326287_0_0_1"/>
    <dbReference type="OrthoDB" id="5284760at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178761" description="GPI anchored protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ33569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="207" mass="20808" checksum="F2D5A5414EAD3123" modified="2011-01-11" version="1">MLPSFFLAFLGGILLIPAQAEEAPTLKSLGSLPSFRISRSGLPVSFAAVGGKCDTGSVKCNDRCMPEGECDGGETCTAGDLCSRSAGDVPNCDPGTTACGNRCMPSDAVCCDGGSYCDTGQICVEGGSCRKGDDKAFEDKDESTTTSMPPAITADLGDTSGEHRTTAAVRGTAAPTTMSASAGALRGAYVNKAALAVGLCAAVSLVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSC6</accession>
    <name>E3QSC6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">YDG/SRA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_08897</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697373">
        <property type="protein sequence ID" value="EFQ33753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097773.1">
        <property type="nucleotide sequence ID" value="XM_008099582.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSC6"/>
    <dbReference type="STRING" id="645133.E3QSC6"/>
    <dbReference type="GeneID" id="24414262"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08897"/>
    <dbReference type="eggNOG" id="ENOG502QRDQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033920_1_0_1"/>
    <dbReference type="OrthoDB" id="2270193at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044027">
        <property type="term" value="P:negative regulation of gene expression via chromosomal CpG island methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.280.10">
        <property type="entry name" value="SRA-YDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036987">
        <property type="entry name" value="SRA-YDG_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003105">
        <property type="entry name" value="SRA_YDG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045134">
        <property type="entry name" value="UHRF1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14140">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE UHRF-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14140:SF27">
        <property type="entry name" value="OS04G0289800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02182">
        <property type="entry name" value="SAD_SRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00466">
        <property type="entry name" value="SRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51015">
        <property type="entry name" value="YDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YDG" evidence="3">
        <location>
            <begin position="197"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ33753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="367" mass="40917" checksum="F14F44B9B82F6CDA" modified="2011-01-11" version="1">MASNNKVPRLPHGRAPADYFNFVKARVLMPLGRLASTAVEETDPRVVEKVQEVMVFLKYVKSCRAAYPTAAPRELFNARYPLKMCLSMIFNPSPAAAKKQYLDAKAKSRAKSLHEWAGRVEDATRIANEQAALQRAQVMAEIQANPMKPNGSLRPPTNHPIWGRTGIMHGLALRPGDRYTVVLDPHCADEKRPANVHGHNGLQVGDWFPSQLSALFHGAHGHSNAGIYFQGEEGAFSVIVAGAYKDLDVDSGETVLYSGSNAHESNDRDNILPSTEATKALATNWVSGKPVRVLRKAHKDSEWAPSHGYRYDGLYEVVEKIFAHNDNNGMFEQFELRRLDGQPPLESLKNIPSQRQVRDLIKSKERY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSJ7</accession>
    <name>E3QSJ7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Acetoacetate decarboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_08979</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697374">
        <property type="protein sequence ID" value="EFQ33835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097855.1">
        <property type="nucleotide sequence ID" value="XM_008099664.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSJ7"/>
    <dbReference type="GeneID" id="24414344"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08979"/>
    <dbReference type="eggNOG" id="ENOG502S9HK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050866_1_1_1"/>
    <dbReference type="OrthoDB" id="9970474at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.400.10">
        <property type="entry name" value="Acetoacetate decarboxylase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023375">
        <property type="entry name" value="ADC_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40518">
        <property type="entry name" value="ACETOACETATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40518:SF1">
        <property type="entry name" value="ACETOACETATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160104">
        <property type="entry name" value="Acetoacetate decarboxylase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ33835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="283" mass="31499" checksum="2942BF61AFF00FA0" modified="2011-01-11" version="1">MAANDITPVPAPWKLKGDIYLFSFWVSGPKAAHPPTIAYSPLEANSSFICPEGNRPLGGISMIQIIRYTESPVGPYDELILCPGFHEYTVEENGKRIKKKNARITRIYVSQKYTCWNGRKNWNIPKHLAAFDWKKNADGSTSVKVFPHDTSGDVKEASASATPLFQATFKTVPYVPSFPLSLSIFKYVGVDPTLVQPPLPEGDGSQCELPGTDQWCSISPGQSCRRASLGWFDIRQADEKGNVVGEHENFWPGLGRWQIGLKMENSDVTFAEPKHWNAPRSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSK9</accession>
    <name>E3QSK9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08991</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697374">
        <property type="protein sequence ID" value="EFQ33847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097867.1">
        <property type="nucleotide sequence ID" value="XM_008099676.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSK9"/>
    <dbReference type="GeneID" id="24414356"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08991"/>
    <dbReference type="eggNOG" id="ENOG502T47A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050237_0_0_1"/>
    <dbReference type="OrthoDB" id="4788965at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180888" evidence="1">
        <location>
            <begin position="21"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ33847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="346" mass="39051" checksum="463BD04039B9D0D8" modified="2011-01-11" version="1">MHVILHIILTIFTLGTNVQSSPAAANILPATNGEVDVAAYASSVEETVARSQMSDAAGLQATNDLTLSTADDKPTWSLWCPKNNWVYYYNWTPLVNFICEQYGDSLENGFNALIPESNYMVDRAKSVTLGWSPIEGGTCKGTCKQVFNTMRTSSGCKAEEFWMKEMINLTYDGCGTASWKYQYQDVAPLKHDSGLCWVEKDEVKTFEPKDGVFERFCYEALYDIRTKGSMRFMDATQRIGYYWTDYNRRVAYPSNASRYYDVGMVHIWIKAPQNVIPCPTKGRYGDDMIEDEVNGLTEELCVKHLTTLQNMDCAQPMGTSQGGRYWADCFEWGIEASGYNARKMSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSL5</accession>
    <name>E3QSL5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cyclohexanone monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_08997</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697374">
        <property type="protein sequence ID" value="EFQ33853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097873.1">
        <property type="nucleotide sequence ID" value="XM_008099682.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSL5"/>
    <dbReference type="STRING" id="645133.E3QSL5"/>
    <dbReference type="GeneID" id="24414362"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08997"/>
    <dbReference type="eggNOG" id="ENOG502SHCE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006937_8_2_1"/>
    <dbReference type="OrthoDB" id="66881at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050775">
        <property type="entry name" value="FAD-binding_Monooxygenases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43098:SF2">
        <property type="entry name" value="FAD-BINDING MONOOXYGENASE AUSB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43098">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ33853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="637" mass="69693" checksum="5C3CC657806E119B" modified="2011-01-11" version="1">MSAPPIASETPAGGAALDFMALNKKYTEEKEKRQRPDGNAQYTEIESDARLSKLAQDPWVNHEELNARPANLADGDEVKVIVLGAGFGGLLFAIRLVQAGLRPGDIRLVDTAGGFGGTWYWNRYPGLMCDVESSIYMPLLEETGYMPKHRYAYGNELLAHANRMAETWGLADQGVFRSQIKSCEWDEDEKRWKVVIEQDRGPNEAPVTMTVRSQFVVLANGILNHPKAPKNIEAFEGDMFHSARWNYGVTGGDPNNLENPQLTGLEGKRVGIIGTGVTAVQLVPQLARWAKDLYVFQRTPASVGEKGQRPIDPEEWKEDRQCENFNIYVSGGEAEENLVADGWTALKAYKATIAAPQDKPLGMADIPGHVGGLLAADAPMSERFRRRVDEVVEDKTTAAALKSWYPTWCKRPGFHDDYLPAFNLPNVHLVDTDGKGVDRATKGSLVVGGADYPLDVVVLSTGYRAPAANMAEPSGCSSMTIKGRGGVLLSDKWHNKGPSTLHGVLTNGFPNLFLTGPLQVGATSNYSSVQDTLSQHCAYIVTEAMKRASNSTDKIALEATVESEEGYSALHMQYAAWFAGMAICTPGYLNNEGEQAPPEEQMKMARGTPFPHGMNAFTKFLEDWRAEGSMKGVEVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSP9</accession>
    <name>E3QSP9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glycosyltransferase family 20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_09031</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the trehalose phosphatase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the glycosyltransferase 20 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697374">
        <property type="protein sequence ID" value="EFQ33887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097907.1">
        <property type="nucleotide sequence ID" value="XM_008099716.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSP9"/>
    <dbReference type="STRING" id="645133.E3QSP9"/>
    <dbReference type="GeneID" id="24414396"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09031"/>
    <dbReference type="eggNOG" id="KOG1050">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002351_2_2_1"/>
    <dbReference type="OrthoDB" id="755951at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005946">
        <property type="term" value="C:alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003825">
        <property type="term" value="F:alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004805">
        <property type="term" value="F:trehalose-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005992">
        <property type="term" value="P:trehalose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03788">
        <property type="entry name" value="GT20_TPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000099">
        <property type="entry name" value="Alpha,alpha-trehalose phosphate synthase subunit, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1020:FF:000001">
        <property type="entry name" value="Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000036">
        <property type="entry name" value="Alpha,alpha-trehalose-phosphate synthase subunit Tps2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1020">
        <property type="entry name" value="Trehalose-6-phosphate phosphatase related protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001830">
        <property type="entry name" value="Glyco_trans_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003337">
        <property type="entry name" value="Trehalose_PPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00685">
        <property type="entry name" value="T6PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788:SF15">
        <property type="entry name" value="TREHALOSE SYNTHASE COMPLEX REGULATORY SUBUNIT TPS3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788">
        <property type="entry name" value="TREHALOSE-6-PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00982">
        <property type="entry name" value="Glyco_transf_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02358">
        <property type="entry name" value="Trehalose_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180761" evidence="7">
        <location>
            <begin position="17"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="19"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="82"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="26"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ33887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="903" mass="102800" checksum="6FC572FFA275E361" modified="2011-01-11" version="1">MTVFIASLFLPKTVHFALPGTSQRGDPLRRVKTDKAQRPEPNRQPSLFNPIRDITPPITPTEEAIAEDPFTNEDGFRIFPEEERKLGAPVDKGSPKWGARATQPKSRASSPPPALIAEHSRTLEKARELGRQGVTQPRPLVRSDSHDRVFAHANWRIMNADQGNGGLRNAAEAAARDGKLGEYTWVGTLGMPTDALEGSQQKQDIEDRLATEHDMLTVFTSDKDFDGHYSHFCKQILWPVFHYQIPDNPKSKAFEDHSWKYYVNVNQAFADKIIKNWKRGDVIWVHDYHLLLVPGMIRKKLPEAKIGFFLHVAFPSSEVFRCLAVRKQLLEGMLGANLIGFQIHEYTRHFLQTCSRLLNVEATTDGLQLEDRFVDVVNLPIGIDPVSLSEHRGDDDVKKWVEIMKERYQGKKLIVARDKLDHVRGVRQKLLSYELFLNKNPDWRDKTVLIQVALSSSEKSDLDATVSDIVTRVNSSWANLAYQPVVYLKQDIDYPQYLALLTMADALMITSQREGMNLTSHEYLFCQDGEVFPEKKHGSLILSEFTGTSSLFGGNELAVNPWDYRQCADAIKKALEMGNEEKERRWGALYSAVMHHTGSHWFSEFLSRLDRVYDEQHKHDQTSVPRLNIHSLASRYKSSNRRLFILDYEGTLVSWGPMNQIIPVSPQRTLDVLNELLLDERNTVYIMSGRRPEELDRLFRRVPNLGLIAENGCFLKDCGKNTWQEMADREQISSWKESVKSIMTYYLERTPGAEIEERRCSLIFHYKSAEDYESAARQASDCASHVNDACEEQRVHAIPLDGSILVEPIDWTKSTAAEKIFDDLRIHMEPDTEHQSPVDFLMVVGDGREDEKVFKWANALGSEKVVQDVVTVSLHSRNTEAGFTLTQGVSGVLLALQKLATTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSR7</accession>
    <name>E3QSR7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Metal ion transporter metal ion transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_09049</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697374">
        <property type="protein sequence ID" value="EFQ33905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097925.1">
        <property type="nucleotide sequence ID" value="XM_008099734.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSR7"/>
    <dbReference type="STRING" id="645133.E3QSR7"/>
    <dbReference type="GeneID" id="24414414"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09049"/>
    <dbReference type="eggNOG" id="KOG1291">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020088_4_1_1"/>
    <dbReference type="OrthoDB" id="409173at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015086">
        <property type="term" value="F:cadmium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005384">
        <property type="term" value="F:manganese ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030026">
        <property type="term" value="P:intracellular manganese ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034755">
        <property type="term" value="P:iron ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001046">
        <property type="entry name" value="NRAMP_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01197">
        <property type="entry name" value="nramp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF037982">
        <property type="entry name" value="Nramp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11706:SF101">
        <property type="entry name" value="MANGANESE TRANSPORTER SMF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11706">
        <property type="entry name" value="SOLUTE CARRIER PROTEIN FAMILY 11 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01566">
        <property type="entry name" value="Nramp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00447">
        <property type="entry name" value="NATRESASSCMP"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="240"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="273"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="318"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="393"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="438"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="484"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="514"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="569"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ33905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="593" mass="63546" checksum="38777C7C61D1EA6A" modified="2011-01-11" version="1">MNRPSRTDEPYEGEGYNQSPNPLSNDLTTNQDLNGTVNARVLEPGEDGKTQSGAADNAILRSHDDWGGDRGAPGARDASPAKSVGLGHPGGEEAMTALLPTLHSRRSTHGGRDESQVQMGIVGRIKSAVIKFGSFIGPGFMISVAYIDPGNYSTGVAAGATYRFRLLFVVLLSNLFAIFLQSLCTKLGTVTGLNLAEACRAFLPRWLNYVLYAFAEIAIIATDIAEVIGFAIGLNLLIPAIPLVAGCAISILDVMIILIFYRPHGSMKGLRMFEFFVVGLVLAVVVCFCIQLSLIRETSVREVFQGYLPSHAVVESQGLYQACGILGATVMPHSLYLGSGIVQARLREYDTKHDLLPPEAEDVGFSSDGIDKGYYVPSAKAIKHCLATSIAELGFSLFTFALFVNSAIVVVAGASIYGNKDAADADIFSIHKLLTDSISQGAGTVFALALLLSGVSAGIVCTIAGQMVSEGALRWKMRPWLRRLVTRSISVTPSIVIAAAIGREGVSDALNASQVVLSVVLPFITAPLIYFTCRNKYMTVRDGAARFRNQSDEESMENTDGLVKMANSWYTAIFAVLVWVIIAAMNVANLVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>E3QT92</accession>
    <name>E3QT92_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 15">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="11 15">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">GLRG_09224</name>
    </gene>
    <organism evidence="21">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 11 15">Belongs to the peptidase C19 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="11 15"/>
    <dbReference type="EMBL" id="GG697376">
        <property type="protein sequence ID" value="EFQ34080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098100.1">
        <property type="nucleotide sequence ID" value="XM_008099909.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QT92"/>
    <dbReference type="STRING" id="645133.E3QT92"/>
    <dbReference type="MEROPS" id="C19.A65"/>
    <dbReference type="GeneID" id="24414589"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09224"/>
    <dbReference type="eggNOG" id="KOG0944">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009884_1_0_1"/>
    <dbReference type="OrthoDB" id="361536at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02658">
        <property type="entry name" value="Peptidase_C19B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14385">
        <property type="entry name" value="UBA1_spUBP14_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14386">
        <property type="entry name" value="UBA2_UBP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000086">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000396">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000587">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000144">
        <property type="entry name" value="Ubiquitinyl hydrolase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016652">
        <property type="entry name" value="Ubiquitinyl_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041432">
        <property type="entry name" value="UBP13_Znf-UBP_var"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001607">
        <property type="entry name" value="Znf_UBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF664">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02148">
        <property type="entry name" value="zf-UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17807">
        <property type="entry name" value="zf-UBP_var"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016308">
        <property type="entry name" value="UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00290">
        <property type="entry name" value="ZnF_UBP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50271">
        <property type="entry name" value="ZF_UBP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 11 15" id="KW-0645">Protease</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="9 11 15" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="7 11 15" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="10 11 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UBP-type" evidence="19">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="UBP-type" evidence="19">
        <location>
            <begin position="152"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="18">
        <location>
            <begin position="303"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="17">
        <location>
            <begin position="586"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="17">
        <location>
            <begin position="651"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="701"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="708"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="12">
        <location>
            <position position="312"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="745"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR016308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR016308-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR016308-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EFQ34080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="789" mass="86767" checksum="BE57418A14516BA5" modified="2011-01-11" version="1">MACPHIESIASALQPPAPSNSVYREDCTQCFDSIDDPAGLDVCLQCFNGGCAGDRNHAQLHRQLWNHPLVLNIRRTRKLVVRDEPPLKMSKLAIAAETEADRYDTKTVVKCLDCNQGLDHSTEKLAPIVDGIMKANTFSRKEEVKAWEQELTSCEHILLMQQAESRTIQSGDLGHCSACDLHENLWLCLDCGNLGCGRKQMGGVDGNSHALAHSQQSGHGVAVKLGSITPEGTADVYCYKCDEERIDDDLGKHLAHWGINLANQQKTEKSLTEMQIEQNLRWDFSMTTEDGKELKPLFGPGLTGLKNLGNSCYLASIVQCLFDTPAFKNRYYLPDRDLPNVQEPAADLETQLRKMADGLLSGRYSKADSDLVASEHSPEIAHQKGLAPAMLKHLIGRGHAEFSTMRQQDAFELLQHIFKLVSRSQHPSDLGDPTSPFRFTLEQRLQCLGCKKVRYSSNEQDNIFIDVPLEKEPVAEGSETQGDAYKAVTLKECLDNFTAEEVVELTCSSCGSKDGYTKRSLFKTLPENLVVNARKMAVINWVPVKIDVPVIVPDEPFLLDDYLSKGLQASEETLPDEPESSAPAFVANAEAVSQLEAMGFGRNRCDRALHATGNSDANAAMEWLFAHMEDPDIDEPLVLDGGSAAAGGGGSADPEKIEMLGAMGFSVPQAKKALRETNGDVERAVEWLFSHPEDQGIFDDDDVAPAVGSESAAAPKSEAGSAATPAKYQLQSIACHKGTSIHAGHYVAFIRKEVDGHPQWVLFNDEKVVEAGEIEEMRKFAYVYFFKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTS7</accession>
    <name>E3QTS7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09383</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697378">
        <property type="protein sequence ID" value="EFQ34239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098259.1">
        <property type="nucleotide sequence ID" value="XM_008100068.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTS7"/>
    <dbReference type="STRING" id="645133.E3QTS7"/>
    <dbReference type="GeneID" id="24414748"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09383"/>
    <dbReference type="eggNOG" id="ENOG502R8WI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002639_5_3_1"/>
    <dbReference type="OrthoDB" id="5362512at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF10">
        <property type="entry name" value="TOL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="35"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="496" mass="54891" checksum="600FBB5D2E0CEDBE" modified="2011-01-11" version="1">MSRAQEVWFPTRLLEVEGPNARLIVTKEIPPKGPYISLSHCWGGADIIKCTEKTLPELRKGVLASDLPGTFRDALSVTRSLGMAYIWIDSLCIVQDSPSDWAAESKTMLNVYQHSILNLAATQSRNSHTGLFVHRAPESLLSGTFTISNGALSGSFIAVEAALDKPYWTAAVDDAPLNTRGWVLQERVISPRVAHFTSDQVIWDCAELTAAETVPSGAQAMPRTVPLGIGQKRGSSLLKVPQEQDRALGQWGTIVKEYSQCHLTVPSDKVVALSGVVDYLRLRLRDKFYAGLWRAQMEMQLCWTVTGSRAAKRNACAPSWSWMSVDCAVDTPQHNEYDGYVVKLLVEVVNVDEAAETDNKGSIWLRGVLSPVTLETQPQHRLVGTGMEHLVHLSLDTADAVDAAGALFFVPVFDVQEPDTGGMYQRFSELRGLLLEELDKEAGRYLRRGHVFASARQDTKSRQFPESYLDFLQAVEQNLPRSSKRGTTSSRLFSII</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTT4</accession>
    <name>E3QTT4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA topoisomerase (ATP-hydrolyzing)</fullName>
            <ecNumber evidence="5">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">GLRG_09390</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the TOP6A family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="5"/>
    <dbReference type="EMBL" id="GG697378">
        <property type="protein sequence ID" value="EFQ34246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098266.1">
        <property type="nucleotide sequence ID" value="XM_008100075.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTT4"/>
    <dbReference type="STRING" id="645133.E3QTT4"/>
    <dbReference type="GeneID" id="24414755"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09390"/>
    <dbReference type="eggNOG" id="KOG2795">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037229_0_0_1"/>
    <dbReference type="OrthoDB" id="5377392at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000228">
        <property type="term" value="C:nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042138">
        <property type="term" value="P:meiotic DNA double-strand break formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000706">
        <property type="term" value="P:meiotic DNA double-strand break processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00223">
        <property type="entry name" value="TOPRIM_TopoIIB_SPO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1360.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013048">
        <property type="entry name" value="Meiotic_Spo11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002815">
        <property type="entry name" value="Spo11/TopoVI_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013049">
        <property type="entry name" value="Spo11/TopoVI_A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036078">
        <property type="entry name" value="Spo11/TopoVI_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034136">
        <property type="entry name" value="TOPRIM_Topo6A/Spo11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10848">
        <property type="entry name" value="MEIOTIC RECOMBINATION PROTEIN SPO11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10848:SF0">
        <property type="entry name" value="MEIOTIC RECOMBINATION PROTEIN SPO11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21180">
        <property type="entry name" value="TOP6A-Spo11_Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04406">
        <property type="entry name" value="TP6A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01551">
        <property type="entry name" value="SPO11HOMOLOG"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01550">
        <property type="entry name" value="TOP6AFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56726">
        <property type="entry name" value="DNA topoisomerase IV, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52041">
        <property type="entry name" value="TOPO_IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10 12 16" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Spo11/DNA topoisomerase VI subunit A N-terminal" evidence="14">
        <location>
            <begin position="107"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Topoisomerase 6 subunit A/Spo11 TOPRIM" evidence="15">
        <location>
            <begin position="229"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="65"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="10"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="12">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF21180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EFQ34246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="420" mass="46225" checksum="FFF18E94B26E6417" modified="2011-01-11" version="1">MFPMDYATSPMINGSQQGRLTSHLSHSSNVVTIPDHDPQQNTTGAAIAKLEDILAAVRESLSRNEEMSIPYRSRRSSASRSSADPARSRTPRSAVRFPGRTVHEATKFSRLMRILQMSLCTLMAGRTITKRNIYYQDENLFKKQSVVDNLVDDLAYTLGLGREDLGIVATGKGLVAGPILIRTKTHHAFHSSSEAPPNLDASSSATGVLIPPARDISQIDFGRARWVLATFRTLAAARYWDASACGSGILVTGKGYPDLLTKQFLHLIHDVKPELPIMALVDYDSDGIAIMRCYSHGSRGHAHERNTVVPSMSWLGIKSGDLAPQSSLLYFQGQVLGGSQRSTRTGLFEHSSSLTKKDRKSAARIIMEIGEDGADCDIMCRRELQVMLFLGIKAEIQAVDDAGDMSSWLDRNMRDHLFTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QU37</accession>
    <name>E3QU37_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_09519</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697379">
        <property type="protein sequence ID" value="EFQ34375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098395.1">
        <property type="nucleotide sequence ID" value="XM_008100204.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QU37"/>
    <dbReference type="GeneID" id="24414884"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09519"/>
    <dbReference type="eggNOG" id="ENOG502TK6J">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048921_1_0_1"/>
    <dbReference type="OrthoDB" id="423576at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ34375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="213" mass="23442" checksum="A8374E02CFB288FB" modified="2011-01-11" version="1">MIYRAISCETSPAFTAARSAQGFLSVALCSLVKDGRIDELFRLHVWLPDGKRGNPDFKLHSHQPFAQSWILAGEGEDHTWEVEPVEDPTEATHAGYVLAWDDGKGQNSTYKTHQSSSTVRNTGSLFRAMETQSEVHCRDSTYTVPAAAFHTSEVAADALHATLFFFDSHRGFVKDAGVLGPKHGDAFTQLRDPAGISPRELVEAVETARLRAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUR6</accession>
    <name>E3QUR6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09748</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697382">
        <property type="protein sequence ID" value="EFQ34604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098624.1">
        <property type="nucleotide sequence ID" value="XM_008100433.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUR6"/>
    <dbReference type="STRING" id="645133.E3QUR6"/>
    <dbReference type="MEROPS" id="S12.950"/>
    <dbReference type="GeneID" id="24415113"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09748"/>
    <dbReference type="eggNOG" id="ENOG502QQGR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020027_11_1_1"/>
    <dbReference type="OrthoDB" id="428260at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050789">
        <property type="entry name" value="Diverse_Enzym_Activities"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283:SF3">
        <property type="entry name" value="BETA-LACTAMASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G07500)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283">
        <property type="entry name" value="BETA-LACTAMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="1">
        <location>
            <begin position="24"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="415" mass="45589" checksum="F75C7A481486548A" modified="2011-01-11" version="1">MPFSAQTGDEIKSIVENAVATDSNPVPGATVVVVDRTGAEQFAYSAGKRGISSGEPMTLDNVFWVASCTKMIVGVACMQLVERGLLKLDDSQQLEKLCPELADIKVLGAEGKLVDKVRGITLRMLLTHTAGFGYTLFNTRLRDWSLPAGVDEFSGSIRDMVQPLLFQPGEGWEYGVNLDWAGIALERVTNTSLNDYIQTNICQPLGLQNVNMFPTPSMKAQLAYMHHRRPDGEIVARDHLLHRPLIVQSEEEIRQCFNSGGAGIFAKPQEYGRILSVFLNDGTCPITKAQILKKETVDEMFTNQISKFPNFSRQGLRDAKPELTNNLPELYTIPGNPPQGWGLTFMITGGTTGRSDGTAWWAGLPNLFWWCDRENGVAGIVCSQILPFGDPAVFGLWSEVEAAVYRGLGISDKIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUU5</accession>
    <name>E3QUU5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">GDP/GTP exchange factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_09777</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697382">
        <property type="protein sequence ID" value="EFQ34633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098653.1">
        <property type="nucleotide sequence ID" value="XM_008100462.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUU5"/>
    <dbReference type="STRING" id="645133.E3QUU5"/>
    <dbReference type="GeneID" id="24415142"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09777"/>
    <dbReference type="eggNOG" id="KOG1426">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005210_4_0_1"/>
    <dbReference type="OrthoDB" id="61110at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051553">
        <property type="entry name" value="Ran_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058923">
        <property type="entry name" value="RCC1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982:SF1">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25390">
        <property type="entry name" value="WD40_RLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00625">
        <property type="entry name" value="RCC1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="237"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="RCC1-like" evidence="5">
        <location>
            <begin position="239"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="298"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="376"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="429"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="484"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="541"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="606"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="312"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="40"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="66"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="140"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="218"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="325"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF25390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ34633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="684" mass="72349" checksum="91A617C0489784F9" modified="2011-01-11" version="1">MPPKGTTKKPAAPKASAPKKAVATSAAPKKAAEAPKKTAAKPVAKKNTATNGATAASKKRKLVEQEQVDESAEESAEEEVEKPATKKNAKKDTEPAARKTKAATAAVKKKAAVAEETEDESKAKKPVKKSAPKKAEPKKTAAASKAETKASAASKKRKSSEEAEDEKPKAKKSKTDDAEVDSQATESAKATESADEEPEVEKPAKSTKKTATAVAKPHPAHPHKVGKKINSAPTQILDIYVFGEGSSGELGLGSRKLDGKKVVDVKRPRLNPHLSAKDVGVVQIACGGMHVAALTKDNKILTWGVNDQGALGRDTNWDGGLRDADAEEEEEDDDDSGINPRESTPTAVGAEYFAPEAKFTQVVASDSATFALTEDGRVYGWGTFRSSDGILGFTEKIQIQKTPEYLPTLKNITALAAGSNHILALDDKGVVVAWGCGQQNQLGRRIIERNKLASLVPQSMGIPKGKINRIACGSYHSFALAKDGSVWAWGLNNFAETGIEMGAGEDDAVVLRPTVVESLKDYKVKQIAGGEHHSLACTEDGKLLTWGRLDGHQVGIPVEELPEDRVIKDESNNPRILSKPTVVEDIAKCVYVAAGVDNNFAIDDKGEAHSWGFSANYQTGQGTTEDIETPTTIDNTAVRGKKLIFAGAGGQYSILGGVADVPKVNGFAALAASQPATGGFRPVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUW9</accession>
    <name>E3QUW9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_09801</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697382">
        <property type="protein sequence ID" value="EFQ34657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098677.1">
        <property type="nucleotide sequence ID" value="XM_008100486.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUW9"/>
    <dbReference type="GeneID" id="24415166"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09801"/>
    <dbReference type="eggNOG" id="ENOG502RN2F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_946685_0_0_1"/>
    <dbReference type="OrthoDB" id="3557800at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180846" evidence="2">
        <location>
            <begin position="19"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ34657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="297" mass="31279" checksum="6E079CF8F3C2C725" modified="2011-01-11" version="1">MKPLKYIILILASTAVAGKVQIAKSIASALSCHLLQGDSLHETAAKAANLGASRGPVEDNDSGGGGKGQTTPAFLSNEGRYQRMWLSKMTRTGLLFPEESRPANEGFSGFGGALLTSTSRRGSGSSIASASSDTVATASTASIASSFTSSGGDVPPPPSIAKYINKPVTWAPLPSDERLRRANPALMVVTHPELDRWHKDCIRKTVGEYRIGVIFVPLDEVEDDELPVLKPLDSRTMTSFASLGSFGACKTGGGGGSLEEEMVLRVNVDANVEHLIDEIVDGVRDLMGSEGGSRLSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVI9</accession>
    <name>E3QVI9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTP cyclohydrolase 1</fullName>
            <ecNumber evidence="4">3.5.4.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">GTP cyclohydrolase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_10021</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>GTP + H2O = 7,8-dihydroneopterin 3'-triphosphate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17473"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58462"/>
            <dbReference type="EC" id="3.5.4.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GTP cyclohydrolase I family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.16" evidence="4"/>
    <dbReference type="EMBL" id="GG697385">
        <property type="protein sequence ID" value="EFQ34877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098897.1">
        <property type="nucleotide sequence ID" value="XM_008100706.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVI9"/>
    <dbReference type="STRING" id="645133.E3QVI9"/>
    <dbReference type="GeneID" id="24415386"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10021"/>
    <dbReference type="eggNOG" id="KOG2698">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049768_1_3_1"/>
    <dbReference type="OrthoDB" id="4966at2759"/>
    <dbReference type="UniPathway" id="UPA00848">
        <property type="reaction ID" value="UER00151"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003934">
        <property type="term" value="F:GTP cyclohydrolase I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006729">
        <property type="term" value="P:tetrahydrobiopterin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00642">
        <property type="entry name" value="GTP_cyclohydro1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.286.10:FF:000003">
        <property type="entry name" value="GTP cyclohydrolase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1130.10:FF:000001">
        <property type="entry name" value="GTP cyclohydrolase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00223">
        <property type="entry name" value="FolE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043134">
        <property type="entry name" value="GTP-CH-I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001474">
        <property type="entry name" value="GTP_CycHdrlase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018234">
        <property type="entry name" value="GTP_CycHdrlase_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020602">
        <property type="entry name" value="GTP_CycHdrlase_I_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00063">
        <property type="entry name" value="folE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006825">
        <property type="entry name" value="PRK09347.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006826">
        <property type="entry name" value="PRK09347.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109:SF7">
        <property type="entry name" value="GTP CYCLOHYDROLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109">
        <property type="entry name" value="GTP CYCLOHYDROLASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01227">
        <property type="entry name" value="GTP_cyclohydroI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55620">
        <property type="entry name" value="Tetrahydrobiopterin biosynthesis enzymes-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00859">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00860">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GTP cyclohydrolase I" evidence="12">
        <location>
            <begin position="134"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ34877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="314" mass="35203" checksum="7219AA7E1EDF919C" modified="2011-01-11" version="1">MARSETGERKGHKHRRNHHNGYSNSSDLSDADTGSQSSKRDSKKRKGGDDDAKVNGHVSKKMRRASLSQPARDPRDTTTAKPSKKKSKNKSEGTVTRSPSPVIDFDGLSRPSLGTRERLEESPEQAAIRLEKLQGAVRTILECVGEDPDRPGVLDTPRRYAKAMLFLTRGYQQNVKDIVNNAIFQEGHNEMVVVKDIEIYSMCEHHLVPFTGKMHIAYIPKNQVIGLSKLPRIAEMFSRRFQIQERLTKEVAYAIMEILKPQGVAVVMESSHLCMVMRGVQKTTASTITSCVLGAFEKKEKTRNEFLSLVGLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVR9</accession>
    <name>E3QVR9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="6">PPIase</shortName>
            <ecNumber evidence="6">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_10101</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 6">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cyclophilin-type PPIase family. PPIL1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="6"/>
    <dbReference type="EMBL" id="GG697386">
        <property type="protein sequence ID" value="EFQ34957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098977.1">
        <property type="nucleotide sequence ID" value="XM_008100786.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVR9"/>
    <dbReference type="STRING" id="645133.E3QVR9"/>
    <dbReference type="GeneID" id="24415466"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10101"/>
    <dbReference type="eggNOG" id="KOG0881">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012062_16_3_1"/>
    <dbReference type="OrthoDB" id="271386at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000008">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF4">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE DOMAIN AND WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="7">
        <location>
            <begin position="1"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ34957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="164" mass="17421" checksum="986C8EC26FD521D7" modified="2011-01-11" version="1">MTTNVALETSMGTIVLELYTAHAPKTCTNFSTLASRGYYNDTVVHRIIPNFMVQAGDPTGTGRGGTSIYGEKFADEIHPALKHTGAGVLSMANAGPDTNGSQFFITLAPTPWLDGKHTIFGRVKNGLSVVKRMGLVKTGPEDRPLETVKIIRASVVDDGGADEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWA2</accession>
    <name>E3QWA2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10280</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697388">
        <property type="protein sequence ID" value="EFQ35136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099156.1">
        <property type="nucleotide sequence ID" value="XM_008100965.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWA2"/>
    <dbReference type="GeneID" id="24415645"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10280"/>
    <dbReference type="eggNOG" id="ENOG502T63V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_762923_0_0_1"/>
    <dbReference type="OrthoDB" id="4827701at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="272"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="363" mass="40228" checksum="1DF14DA8B2DA4911" modified="2011-01-11" version="1">MTDFEETGKRSGDDIGGRNKRRRLEPPQSHTNMRTLLRAAGLGGETPISNSTEQQELGHANRTKPPPAVSDPVALYRRGRYIPTGAGNHQIRVPAFLRVVSPDGEAPHTQEAEAPKSPRLSPSREAPTSRPPSSVPLDRRPAANPQSNVKAVRVCPQCRDVPLGPGPIVNGEPTYPVCESCRQANIRRQVLRGIAAQALVELSQRVTSRAPEQNDQVQDVRGQFLNGLGRLPKRPQEFTCLRCKRPHMPLAPGRRRCVECICILIAFGPDGGEEQAAADASQRPEGKRGKRPAELEQQPQDEHWHMCDGCFKKPVPPGERKCPRCVVRFALMHRMQNIWALPGLPCVSCVHERGRKQREPKIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWJ3</accession>
    <name>E3QWJ3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fungal specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_10375</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697390">
        <property type="protein sequence ID" value="EFQ35231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099251.1">
        <property type="nucleotide sequence ID" value="XM_008101060.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWJ3"/>
    <dbReference type="STRING" id="645133.E3QWJ3"/>
    <dbReference type="GeneID" id="24415740"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10375"/>
    <dbReference type="eggNOG" id="ENOG502S2FW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016574_7_0_1"/>
    <dbReference type="OrthoDB" id="2740448at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF28">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="11"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="60"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="680"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="60"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ35231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="700" mass="76464" checksum="C720B20F63ED28F7" modified="2011-01-11" version="1">MSTGRKIGKRACDACKIRKIKCTEVPPCDGCVAIRTACTFNKVPATRGPRNLRAKTIRQIAQAQQESAAAPPSSDSPTGDGAAVASTPAGAAAPSRSSLSPDGASSEGAGDPTGRLRLVRQETTALQAQRTPSASLVLRLCIYRLRLFPVWPIIAVEEIMASLSRDADDLDSYVLANAVGAATIAQLKLTTTDNDDPATASSMEAECQRSRMALQEREGGPPMNLNWLRTSFFLHVYHENQQPGGAKSLLYLREAITIAQIMGLHKESSYMALPLPEQQMKRRILWLLFVTERGVAMLHKLPVVLKSNIRFPSLDGSGVGEDEGHVLPAFKKLANLFWIFDQSGAFDILQNSDDEDAMWSMADGLQTASRACLDVVQRKLQEIPLDSDASNDVQRADIVVTRQWMQAVLWKVTMNHGRPWSSGDCSNDNNTNNNSTNVTSLSHPIHIAKEFLQLISQLPSTAIEAHGPGIEFKIYEIASAVTDAVANNFRLPRSSTDGPRDILLQLQRVLASCRGGNKALLEMLCARISEIQHGPLLAMNKTLTPRVQEIDDDQWRNERAAPANGQTNLFTATNDMPDSNQTYAQAQASFLSMFNRDGAAQSLGSSGPMPIPLQRQDLGRPIWDHQNQMGPGAHDLIEQLQNFDGSFNAVESNGTLDMLFANGVSWDNVANDDWMASVQNNPGAFNSSTQPSTDLQRTYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWK0</accession>
    <name>E3QWK0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_10382</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697390">
        <property type="protein sequence ID" value="EFQ35238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099258.1">
        <property type="nucleotide sequence ID" value="XM_008101067.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWK0"/>
    <dbReference type="GeneID" id="24415747"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10382"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_13_1"/>
    <dbReference type="OrthoDB" id="6133115at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000117">
        <property type="entry name" value="MFS hexose transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF31">
        <property type="entry name" value="HEXOSE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="82"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="203"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="359"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="392"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="425"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="463"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="44"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ35238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="529" mass="59721" checksum="38033B05708C6090" modified="2011-01-11" version="1">MGFLKGLSQKKPKSEVVAQAQEEAPEFERVNWMKDPGLRKLYFYAIVLCIASATTGYDGSFFNSVQNFDSWEEFFDHPKGGQLGLLSAFYQIGSLISIPIVPWVADNYGRRIPIIFGCVIMVAGAILQGACQNLGMFMGGRVLLGFGNSFAQIASPMLLAELCHPQHRARLTTVYNCLWNVGALVVAWLSFGTDFLGNEWSWRIPAIGQAVPSVIQLLFIFWVPESPRFLIAKDRHDEALQILGKYHANGNTDHPTVQFEFREIRETIKREIAAKNSTSYLDFFRTPGNKYRFMMLISLGLFSQWSGNAIISNYTNILYTNAGIESSTSRLGLSAGQTGLSLIVSVTLAMQVDRFGRRPIFLASTAGMLMTFVFWTLSDGLFEEYGSPGSNYAMIFFIWLFGFFYSFAWSGLLISYSIEILPYKLRAKGLMIVNLTVQAALTLNNYANPYAFEYFKGHTWKLYLIYTCWIFLELTFVYFFYIETKGPTLEELVKVIDGPDAEVADLDLAQVEQEVKIGHEAEELEHKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>E3QX52</accession>
    <name>E3QX52_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">PAN2-PAN3 deadenylation complex catalytic subunit PAN2</fullName>
            <ecNumber evidence="10">3.1.13.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">PAB1P-dependent poly(A)-specific ribonuclease</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Poly(A)-nuclease deadenylation complex subunit 2</fullName>
            <shortName evidence="10">PAN deadenylation complex subunit 2</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PAN2</name>
        <name evidence="13" type="ORF">GLRG_10584</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. May also be involved in post-transcriptional maturation of mRNA poly(A) tails.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Exonucleolytic cleavage of poly(A) to 5'-AMP.</text>
            <dbReference type="EC" id="3.1.13.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="10">Binds 2 metal cations per subunit in the catalytic exonuclease domain.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="10">Positively regulated by the regulatory subunit PAN3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Forms a heterotrimer with an asymmetric homodimer of the regulatory subunit PAN3 to form the poly(A)-nuclease (PAN) deadenylation complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">Contains a pseudo-UCH domain. This ubiquitin C-terminal hydrolase (UCH)-like or ubiquitin specific protease (USP)-like domain is predicted to be catalytically inactive because it lacks the active site catalytic triad characteristic of thiol proteases, with residues at the equivalent structural positions that are incompatible with catalysis, and it cannot bind ubiquitin. It functions as a structural scaffold for intra- and intermolecular interactions in the complex.</text>
    </comment>
    <comment type="domain">
        <text evidence="10">The linker, or PAN3 interaction domain (PID), between the WD40 repeats and the pseudo-UCH domain mediates interaction with PAN3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the peptidase C19 family. PAN2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.4" evidence="10"/>
    <dbReference type="EMBL" id="GG697393">
        <property type="protein sequence ID" value="EFQ35440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099460.1">
        <property type="nucleotide sequence ID" value="XM_008101269.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QX52"/>
    <dbReference type="STRING" id="645133.E3QX52"/>
    <dbReference type="GeneID" id="24415949"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10584"/>
    <dbReference type="eggNOG" id="KOG1275">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002369_1_0_1"/>
    <dbReference type="OrthoDB" id="16516at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031251">
        <property type="term" value="C:PAN complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004535">
        <property type="term" value="F:poly(A)-specific ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000289">
        <property type="term" value="P:nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06143">
        <property type="entry name" value="PAN2_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02672">
        <property type="entry name" value="Peptidase_C19P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000459">
        <property type="entry name" value="PAN2-PAN3 deadenylation complex catalytic subunit PAN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000028">
        <property type="entry name" value="PAN2-PAN3 deadenylation complex catalytic subunit PAN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03182">
        <property type="entry name" value="PAN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030843">
        <property type="entry name" value="PAN2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050785">
        <property type="entry name" value="PAN2-PAN3_catalytic_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048841">
        <property type="entry name" value="PAN2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028881">
        <property type="entry name" value="PAN2_UCH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15728">
        <property type="entry name" value="DEADENYLATION COMPLEX CATALYTIC SUBUNIT PAN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15728:SF0">
        <property type="entry name" value="PAN2-PAN3 DEADENYLATION COMPLEX CATALYTIC SUBUNIT PAN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20770">
        <property type="entry name" value="PAN2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13423">
        <property type="entry name" value="UCH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10 13" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 10" id="KW-0540">Nuclease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="USP" evidence="12">
        <location>
            <begin position="490"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1097"/>
            <end position="1158"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="899"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="901"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="1008"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="1061"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ35440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1158" mass="128698" checksum="0F3861056D243055" modified="2011-01-11" version="1">MDGDWDEVARIPFPPPGVHAMATPVTTMTFDTAQDLLWTGNDYGRVTSFYGSELQRYTSFKAHTTPDGPVRQILVNDKGVVVLGSRDIHMASRKGPPIWHIRHDDMKDLRCMSFTSKGTSEILVAGFQDTMFVVDLAKGEVVKQVPTARSYKLMKRSRYICAATKDGTVDLIDPVNFSVVKSWSAHSALISDMDAQHDFIVTCGYSLRQGQNYMLDPFLNVFDIKKMSSMSPIPFPAGAAFVRMHPRMSTTSIVMSQGGQMHVVDLMNPNTSNVRQANTMTYLTMFEIAPSGEAVALADAEYNIHIWGSPSKLRFVDFASQTEFATPEEPLPPIEWTADTPLNSVGMPYYREVLLSAWPDLISDIGAPPTKLEPQFVAGLKQSELGLYGRNTRGLRRNQVEDTRNLDKGNASGILAPKFLSEKAREFAKTPVGNASGDDKVDGVANSLAQLDIDPTKAECPPMYRNVEIKYSKFGVDDFDFGFYNRTHYSGLEIHIANSYANSLLQVMHFTPLIRNMALQHAATACVADTCLLCELGFLFDMLQKADGSICQATNMLKTLSHHPQAGPLGLLEEDPNGSTLTVMLQGLTRFLLDKIVQDYRSIPPGSNFMEQMLATSATSSIRCMNCRSEYTRPGSTYVNDLMYPQTTGNTGRNQKAPKVTFSQILKSSVERETTSKGWCSRCQRYQTIATRKTIHNIPAVFMLNTAVGNAEQRRYWSTPGFLPEEIGVIVDHGQFFCYEGEDLKLHLQRGIHNITVYSLIGMAMNIDPGPGQKPHLVAMVNVAHAQPTAPEASQWHLFNDFLVRSVSAEEALSFHPSWKMPSVIAFQVKEANNKIDMDWQKNIDTSLLYEDKKFETLESFPVTDGSLTTASPHIDGKTYRALDSASEQPGPDSIVALDTEFVAVRQPEIEMNSDGERETIRPIVYALARASVVRGQGEDEGLPFIDDYISIREPIVDYLTSYSGITHEDLDPRVSKHNLVPLKVAYKKLWILLNLGCKFLGHGLKQDFRVINIHIPRSQVIDTIDLFFLKSRLRKLSLAFLAWYLLKEDIQLETHDSIEDARTALKLYRKYLEFEDAGVLEPMLQDIYRAGRDVNFRPPARSGQAADVQRTDTPPPLPTHGTAVTPSTPGAVSIGPSSSGGFGAGSTWTPGKGSPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXV0</accession>
    <name>E3QXV0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_10843</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697398">
        <property type="protein sequence ID" value="EFQ35688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099708.1">
        <property type="nucleotide sequence ID" value="XM_008101517.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXV0"/>
    <dbReference type="STRING" id="645133.E3QXV0"/>
    <dbReference type="GeneID" id="24416208"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10843"/>
    <dbReference type="eggNOG" id="KOG4177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020808_0_0_1"/>
    <dbReference type="OrthoDB" id="341259at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:RNA nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24141">
        <property type="entry name" value="2-5A-DEPENDENT RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24141:SF1">
        <property type="entry name" value="2-5A-DEPENDENT RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="251"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="285"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="319"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="352"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="384"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="417"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="450"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="483"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="551"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="584"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="648"/>
            <end position="680"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ35688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="722" mass="78408" checksum="8FD5629E0218DE46" modified="2011-01-11" version="1">MDSPGRLPGVGLADLIRASELLADRFDLVAKSLNTAPVTLTAVAKECRAVTDALRRFKYLRETIPETLVFDPVLLDESCHDALNSIFNDLSSLDIYSTRIRPATSDSNVDMSSGQITIIWNESYLKQMIRQTKISRQSLAFLLNCVPRARPRPDIYPISDLSGIHSALKRLKPPPGTIYRQSPRTTKDLHDAIDHEDEAAVVKLLLQRIDPNVPRFGSKLSPLRRALGRQTPSLVTFLVMAGADLEDRDDQGETILITAVKYAYSDKIIALLCDLGANVNAVDNLGCSAFHHAAMSANEDDTLAVLIHAGADVDHRDFASRTPLIAAVQNYRFKNIEKLLEYGADLETRLQNGQTALHVAISMKSRPMTEFLSDQGAYLDRPVNGHTALTYAIATECSDIAEVLIEAGADVNLPGSQGNFPLQAAAAVGDQRTTKLLLSRGAKYEAIGTDGFLPVHIAAHENQVEVLRLLLKAGSAIDPITERGETPLTIATYFGCFEAAQSLIEAGADVDYATLGADNIICQALKAGHTRIAVALVQGGADITYTLLRNASMTPLHLAAHYGQDDVLAAMINAGADLETRTWPGFTPLFPAVRAGHLSTVRLLLAAGAFPRVRSMSGANLLFVGIAEPAMMKLLIEIGLDIHERDYHGATPLHYAALHGHTATVKLLLQRGATLVHASAVYETLHDYKQKGPYRQGTPAGLARQTGHIKIARLIEGWKYKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXW7</accession>
    <name>E3QXW7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Mpv17/PMP22 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_10860</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697398">
        <property type="protein sequence ID" value="EFQ35705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099725.1">
        <property type="nucleotide sequence ID" value="XM_008101534.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXW7"/>
    <dbReference type="STRING" id="645133.E3QXW7"/>
    <dbReference type="GeneID" id="24416225"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10860"/>
    <dbReference type="eggNOG" id="KOG1944">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049109_8_0_1"/>
    <dbReference type="OrthoDB" id="10267969at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266:SF50">
        <property type="entry name" value="VACUOLAR MEMBRANE PROTEIN YOR292C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ35705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="272" mass="31005" checksum="5483F7625A72C05B" modified="2011-01-11" version="1">MSWELSRRRIVRAVNSKYLYGRLPLLHAVIALIEMALVARLVSKFNQYYDERPLLTMMVTNAILGGIADTTAQTITALRLKAIRKPGGLNKDDGVAIEIHDLDRKNPFYEKDLIPDARHLPPPFDFERLTRFMAYGFAMAPLQFRWFKFLSSTFPITKTSAFVPAMKRVTFDQLIFAPFGLLCFFSVMTVAEGGGRRAVMHKLRDMYVPTLKANFLVWPAVQVINFRLMPVQFQLPFVSTIGIAWTAYLSLANASEEVDTRPAREDAHIRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QY55</accession>
    <name>E3QY55_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_10988</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697400">
        <property type="protein sequence ID" value="EFQ35793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099813.1">
        <property type="nucleotide sequence ID" value="XM_008101622.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QY55"/>
    <dbReference type="STRING" id="645133.E3QY55"/>
    <dbReference type="GeneID" id="24416353"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10988"/>
    <dbReference type="eggNOG" id="ENOG502RZ8N">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_683357_0_0_1"/>
    <dbReference type="OrthoDB" id="5242705at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021514">
        <property type="entry name" value="DUF3176"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394">
        <property type="entry name" value="DUF3176 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394:SF5">
        <property type="entry name" value="DUF3176 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11374">
        <property type="entry name" value="DUF3176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="121"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="157"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ35793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="403" mass="43886" checksum="302D20BE5DCDAEF9" modified="2011-01-11" version="1">MSSPALPSETDGANDLRPGSNGQIHPPSRRRGMPIEEQRSNSFEDSRDTCAGDERMAFISPSSSGISENETLKAASGSTASEQHPHNREAARLSEGETSSHQKEQNALPRNDTTPESAWTVWWIEIFSSILALACIIAMVVVLYLHQGQPLPRWPKLISINSLIAIFTAIFKASLILPVAEGLGQLKWNWFDRFHKLGDLVAFDNASRGPWGSFLLLMKCIPRPDRGYLAGLGALITVAALAIDPFSQAMISHNSCEITADFGLAEVSRTINYSGNMDTYEGIGAVINQPMLRAIYRGLVDLPKPGELVDFACTSGNCTFERDGGGSYSSSLGVCHLCDDVTEKAVNVSEKGPSGHTITTWHLPWSVDMTAERLFKVRGSGRHVTMRPTPVLAYENRTAPTGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYG2</accession>
    <name>E3QYG2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glutathionylspermidine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_11091</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697402">
        <property type="protein sequence ID" value="EFQ35900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099920.1">
        <property type="nucleotide sequence ID" value="XM_008101729.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYG2"/>
    <dbReference type="STRING" id="645133.E3QYG2"/>
    <dbReference type="GeneID" id="24416456"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11091"/>
    <dbReference type="eggNOG" id="ENOG502QUZK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059175_0_0_1"/>
    <dbReference type="OrthoDB" id="64566at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005494">
        <property type="entry name" value="GSPS_pre-ATP-grasp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03738">
        <property type="entry name" value="GSP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutathionylspermidine synthase pre-ATP-grasp-like" evidence="6">
        <location>
            <begin position="3"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ35900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="451" mass="51260" checksum="6D91DECE49EF6355" modified="2011-01-11" version="1">MRLVQSQGLVYADAIGSHESEPYWPDNRYYSFTLEEIELLEKAARDVFEMCCKAADYLTENKTIMEKMAIPPFAYEQITKSWDRQPPWGSVYGRFDVCFGGLQHPDTRLRCPKFYEFNADTPTSLLESAYIQWLWLEQTGHGNDQFNSISENLIEAWKRNLTLIDEKLGYKPTVYFATCESESTGEDAMNAMVLMETCQLAGWKTKAISVGEIGISLADGRFHDLEGNHLDVVFKLYPWEFMVEEAGGQVCFTDMGSSDGTIWIEPPYKMLWSNKALFAVLWSLFKDDERSKWLLPTYFEDDSVPASLTKYARKPIFSREGGGITLKADGEVIQTEPDKAYGKEGYIVQELALPPEFKDAENKPHYPVLGIWMIDGEPAGMGIREAVTPITTNVSAFIPHSIEDGPVNYERQAVSTEEEISRALDIARFSDPKQVGAEQTEMLKYIERLCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYJ7</accession>
    <name>E3QYJ7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_11043</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697403">
        <property type="protein sequence ID" value="EFQ35935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099955.1">
        <property type="nucleotide sequence ID" value="XM_008101764.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYJ7"/>
    <dbReference type="GeneID" id="24416408"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11043"/>
    <dbReference type="eggNOG" id="ENOG502QUXC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_23_3_1"/>
    <dbReference type="OrthoDB" id="2105912at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17324">
        <property type="entry name" value="MFS_NepI_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42910:SF1">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42910">
        <property type="entry name" value="TRANSPORTER SCO4007-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="163"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="222"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="252"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="284"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="335"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="363"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="4">
        <location>
            <begin position="95"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="497"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="33"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="48"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="511"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ35935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="535" mass="58043" checksum="600379C72CDE0953" modified="2011-01-11" version="1">MSHRRNSNGAEAAAEHASNPQARAASSILGGSGEEKEGRAPTGRETRSTTPSPSNSDCESNPAKGRGGIVNWVVRTLTWTPRRLRYDAENPPEFTLALNFMFAVAATFTVANLYYNQPVLNRIAETFDVSFERASSVATLMQAGYAAGLLFICPLGDMVRRRPFILGLIWVTAMLWLGLCVTNSFAAFLALSFMVGATTVTPQLMLPLVADMAPAHRKASSLSITTSGLMLGMLIARLLSGIVANYTSWRNIYWIGFGAQYVILVLLFFFLPDYPSKNPDGLNYLRALWTIVTMLFTEPVLVQACLIGFFISAIFTSFWTTLTFLLASPPYEYPSVTIGLFSLIGIAAICGGPVYGRLVMDRYVPFLSSVVGQVAILAGCIVGAFTGEFTVAGPVIQAICIDMGIQTAQTANRTSIYTINAKARNRVNTAYMVCVFCGQLTGTAVGNRLYAQGGWKYSGGASIGFIGLSLTLTMLKGPREKRWIGWSGGFKLRRDEVLKKAEPASPEDGQEAGKSEEERTGEEKTEAGASEEIRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYN8</accession>
    <name>E3QYN8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_11120</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697405">
        <property type="protein sequence ID" value="EFQ35976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099996.1">
        <property type="nucleotide sequence ID" value="XM_008101805.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYN8"/>
    <dbReference type="STRING" id="645133.E3QYN8"/>
    <dbReference type="GeneID" id="24416485"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11120"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_43_5_1"/>
    <dbReference type="OrthoDB" id="5290825at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015798">
        <property type="term" value="P:myo-inositol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015791">
        <property type="term" value="P:polyol transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000474">
        <property type="entry name" value="Sugar transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050814">
        <property type="entry name" value="Myo-inositol_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020:SF40">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="221"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="251"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="371"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="406"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="435"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="464"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="502"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="531"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="119"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ35976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="624" mass="70433" checksum="8541DDA381EB2355" modified="2011-01-11" version="1">MADKINLEGEKVADVSGYHEERGTGQPDPIELSRNIEAKIKNPLEGIGYNQLMRDVEVFCRDHGLQEEIAVFRKGALVAQDPENYENIGGAEALDEAEIKALREEVTHKWRLPKKLYLTIITCSIGAAVQGWDQTGTNGANIFFPAEYGIESNSTRDRLILGLVNAGPYIGSALCGCWLSDPLNHYFGRRGVIFFSAHFCIWPLIGSAFSHNWQQQLANRLLMGIGMGAKASTVPIYAAENSPPSIRGALVMSWQMWTAFGIALGTAFNLAVYYAKYNWRLMLGAPFLPAVPLLLLIYLCPESPRWLMKKGRYHDAWKSMIQLRHNPIQCSRDMYAIHAQLQLENQVLGKSSYVSRFKELFTIPRVRRANLAAFTVMIAQQMCGINIIAFYSTTIFKEAKMGDFEALLGSFGFGMVNWLFAFPAFWTIDTFGRRSLLLFTFPQMTWTLLAAGLCTLIAPGITRTALVSLFVYLFGAFYSPGEGPVPFTYSAEVYPLSHREMGMGFAVATCLFWAAILGMTFPFILDRLQVVGAFGLYAGFNVVAFCMILFWVPETKQRTLEELDWVFALPTSRFAAYQVTKAIPYFFRRWVFFDRSAKLEPLYTFQQPDRTERVVSSDEEKKTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZ90</accession>
    <name>E3QZ90_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_11319</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697413">
        <property type="protein sequence ID" value="EFQ36178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100198.1">
        <property type="nucleotide sequence ID" value="XM_008102007.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZ90"/>
    <dbReference type="STRING" id="645133.E3QZ90"/>
    <dbReference type="GeneID" id="24416683"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11319"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_1_1"/>
    <dbReference type="OrthoDB" id="1888931at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050085">
        <property type="term" value="F:mannitol 2-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050664">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019594">
        <property type="term" value="P:mannitol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000090">
        <property type="entry name" value="NADP-dependent mannitol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF13">
        <property type="entry name" value="L-XYLULOSE REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ36178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="278" mass="29560" checksum="C126F2C7B3B4CE90" modified="2011-01-11" version="1">MTINGGTNGTTKSIRAPNPPIEDSVFKQFRLDGRTVIITGGAGGIGSEIARGLAEAGANIAIWYHTSKAAVAIAESIAQDFGVKAKAYRVDVTSYSDIEAAVAYAVEDFGRLDVMVANAGVPSKAGGLDDGIEDWNRVRAVDFDGAYYCMRAAGLVFRDQKSGVGIITASMSGHAVNVLQEQSCYNACKAGTIHLARSLAVERAKLGGRINSVSPGYIDTAMSGDCPFEMKEEWFGLTPLRRDTDPRELKGIYLYLASDASSYTTGVDFIIDGGYTAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3R073</accession>
    <name>E3R073_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11656</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EFQ36511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008102340.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R073"/>
    <dbReference type="STRING" id="645133.E3R073"/>
    <dbReference type="GeneID" id="24417020"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11656"/>
    <dbReference type="eggNOG" id="ENOG502QR0D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1402320_0_0_1"/>
    <dbReference type="OrthoDB" id="5424209at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="194" mass="21147" checksum="C05C69F231D9A4D5" modified="2011-01-11" version="1">MPHSLAQQPNRNTRTNNAYTRDRLLSQTWTTSHTRPPTTSAHGTTTAFRASPGLLVARSSTTPFKPIDNAWSSDSKTLTVVGEHPIVSQWNNDRSSLRNEIVAIPTSEAVEWQAIDVIRIGDARDDDMPVAVSISIMAATLSWDVGNRVAWRCQCALDEHGLKDVCCKIKESAIVNLASTPAVLKQSLDIKGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11762</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EFQ36617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008102446.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0H9"/>
    <dbReference type="GeneID" id="24417126"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11762"/>
    <dbReference type="HOGENOM" id="CLU_3068570_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="53" mass="5895" checksum="C7246CD4F9A61B73" modified="2011-01-11" version="1">MGGATVFVVFDWTTSRTISTLEHAKCLIVEPSTEQLERKVESRPKNPPPPEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0Z0</accession>
    <name>E3R0Z0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11926</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697533">
        <property type="protein sequence ID" value="EFQ36778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008102607.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0Z0"/>
    <dbReference type="GeneID" id="24417289"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11926"/>
    <dbReference type="HOGENOM" id="CLU_1643563_0_0_1"/>
    <dbReference type="OrthoDB" id="10584876at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003181069" evidence="1">
        <location>
            <begin position="23"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="161" mass="17746" checksum="209BEB682DC48DAF" modified="2011-01-11" version="1">MARYFTLFTTMISFLSLGLATAAIVRVDDYVVLNGTALLFDPVGGFNDTTRDLAWQADYFQTLDLLAINALYREANAGISQRDLRPRTGPTCLACMVVQLASGVASSRTEAFVTCSQTTSSCDSLTITTLESNVKRYWIAAGIGLYTAGNYAYDVWSQYRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q1Y7</accession>
    <name>E3Q1Y7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Amino acid adenylation domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_00232</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089108.1">
        <property type="nucleotide sequence ID" value="XM_008090917.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q1Y7"/>
    <dbReference type="STRING" id="645133.E3Q1Y7"/>
    <dbReference type="GeneID" id="24405597"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00232"/>
    <dbReference type="eggNOG" id="KOG1178">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005562_2_0_1"/>
    <dbReference type="OrthoDB" id="3142841at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052979">
        <property type="entry name" value="Adenylate-forming_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33927:SF5">
        <property type="entry name" value="ENZYME, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G01222)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33927">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="627"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="708"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="739"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="781"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="814"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="4">
        <location>
            <begin position="41"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ25088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1041" mass="114430" checksum="B6D0E99EE55AD5AA" modified="2011-01-11" version="1">MVHSRSFHSLESLSLADRVLFNQFSRGPSESVPYQVVHHAFESIAAAHPDATAVRHYDDTSITYRELNRRANVLANELRATYGVRKGDRVVLVYSRCIEMVVFILAVLKAGGQYVPLDGGIIPEDTLGYDIADSNAPVVLCLPKFREKVLRSLPSDRRDLVRVVDLDGNDSLWKHGNAGHPGVIVNPEDGAYVIYTSGTTGRPKGVDVRHEGVTNTLLVEPSRLGIRVGKNVAQQLNVGFDMCAWEILGTVMNGGTLHIRGSGNDLWTDCLQRVDTVIATPSVVLKHMPRREDFPNIRTIAVGGEPCPLALAEQWAPYVKFWNVCGPTEISILNTAHLHRPGKTLSIGKPNPNTNVYILDDDENPVPIGEPGTMWAGGLGVSRGYLNLPDLTAQRYRPDKFTKDGRMMFNTGDLARWLEDGSLEPLGRKDDQVKISGFRVELDGVSRAIEKCPGVVKGCALKIDDRLWGFYSAPAPIDEPQLKAIVGEGQPFYAVPTVWKYLPAIELTPNGKVDKRALRDIAAGATTAPPRPPLPPIATAMPMPELSSSASSVKTAASPSSEGGLTLVDSRTFTVIDSHRNIDLEKTAAFVAEEIEKQDEDYELPSKKGFHGWRWIRHRGLNAYRKLFGVIFLSNLAVFALLLWDSRNMNFSLPLNHLATAVAANLLGAVLLRQEYVVNFIFWMCSRVPTSVPLSIRRHFARVYHNGGVHSGCAVSATVWWVIFTGAATGNFLAPKSLYSINLITLVLTYLILLLLSMILVMAYPSIRAKMHDQFEWTHRFAGWTALALVWAHVIATAASMSSEPLGPTLVKTPALYLVAATTLSIALPWMRLRRVKVVPEPLSKHAVRLHFDFCTPPPCTSRGVRITDRPMVEWHAFAAIPEPSGKGFSIVVSKAGDWTKRIIENPPTSIWTRGTPASGVLAVAPLFKKMVLVATGSGIGPCLPVLMERRVPARVVWSTKNPIKTYGQGIMDTILAADPDALIWDTDQMGRPNLVQLAYNVYKESGAECVAIISNGPTVNKFVYQMESRGVPAFGPIWDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2M0</accession>
    <name>E3Q2M0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NUDIX domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00465</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089341.1">
        <property type="nucleotide sequence ID" value="XM_008091150.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2M0"/>
    <dbReference type="GeneID" id="24405830"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00465"/>
    <dbReference type="eggNOG" id="ENOG502S8JU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067850_0_0_1"/>
    <dbReference type="OrthoDB" id="276276at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02883">
        <property type="entry name" value="NUDIX_Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43736">
        <property type="entry name" value="ADP-RIBOSE PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43736:SF1">
        <property type="entry name" value="DIHYDRONEOPTERIN TRIPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="41"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="209" mass="22682" checksum="5CAAE3F0A921A5D6" modified="2011-01-11" version="1">MEQPTTTTQDPAANLAHPTSLKCYNLPMRAWLENNGKATELDGLATSALVFDRRGRVLLLQRAAHDSMPLRWEAPGGAVDDADPSVLAACARELREETGLGAVRVVRVVSEGAGKEPGSSLTNRTGTLTLLRFAFEVEVEVEAVAPGGDGEGDEIAVRTDPEEHADHVWASEEEVMRERVGEKDIPITNAQMASLILDGFRRRREEGVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2S5</accession>
    <name>E3Q2S5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00048</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ24904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008088924.1">
        <property type="nucleotide sequence ID" value="XM_008090733.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2S5"/>
    <dbReference type="STRING" id="645133.E3Q2S5"/>
    <dbReference type="GeneID" id="24405413"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00048"/>
    <dbReference type="eggNOG" id="ENOG502QWIX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010595_7_1_1"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF10">
        <property type="entry name" value="ABC TRANSMEMBRANE TYPE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="17"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ24904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="367" mass="41547" checksum="67EE6492FC164F70" modified="2011-01-11" version="1">MAEPTTKEETVPPAGSGTASPSQPTTASPAVPDPPENANEAEVIEHDDVDNASETASTVDDRWSTYTGSLTSSVFDYPTEHGRRYHAFRSGSYWGPNDETEMERLDFNHMLIVKVIGNKLYLAPLDKNKIHRILDVGTGTGVCAIQMGDEFPNAQIIGNDLSPIQPTWVPPNVKFEVDDVESPWLIAEKYDFIFCRYMAGSLGDWPKLMRRVFRNTNPGGWVEFQDYNLRWKSDDGSLTEKHFTNEAVNNFLEACKLVNREPAPGPKLEGWVKDAGFVNITHQKFKIPVGDWPKDPHYKECGLINLMQTLEGLEGFTLRMFTSVLGWTKEEVIVLLAEVRRELKTRTFHAYFDFHVVYAQKPEVEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2X9</accession>
    <name>E3Q2X9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WHIM1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00102</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ24958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008088978.1">
        <property type="nucleotide sequence ID" value="XM_008090787.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2X9"/>
    <dbReference type="STRING" id="645133.E3Q2X9"/>
    <dbReference type="GeneID" id="24405467"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00102"/>
    <dbReference type="eggNOG" id="ENOG502QSZU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023536_0_0_1"/>
    <dbReference type="OrthoDB" id="349045at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42107:SF1">
        <property type="entry name" value="WHIM1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42107">
        <property type="entry name" value="YALI0D24453P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="565"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="389"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ24958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="586" mass="64596" checksum="8F0E711994CDDE6F" modified="2011-01-11" version="1">MADDDSSDLSSLSSLSPVPSDIESDAEPELETKKGDGILKFFPKLTKGKKTATAAKEPSPPPRKRSPSPPHENTFEDNPDIAFLVMFRSRFNDAFPKSLANFGPQELERGIIDNPPSERVEAFLCALLFLLLNRKQDVKAGQYSKALDDALSAHKSQWPKSWGGVNPLSGNNTFHSITPTQRLSLLRALALWSLSASETVKTIINKSYKGNRHDDDLNQPLSVQPWGSDSDKRRYYLIEGLDDTAFRVYRESNPAGFNRTWRSVAGSIDEIKALADKLSTKDGGPRARKLADQMLQAIPRFEATEEKRRRREYRQAQKARFKRPEPGFSVYEGRTRGKRIKYTYSDDEDFTDSSSRRSARNTGTSTPAEPVGPVTTASGRQIRAPPRLNASSAAGSVNGDSEDSHQQSEPAVGPGGRPRRAAVVNHGTNGWSAKGSRTRGNKSMDDDDDDVSEPDLGDDEEDHVPDETEEDDEEDLDEDVEMADDDLADEPRKSLIVKLSVKKSPTTTKMAMITPASEDERAMANNDELADEIIAKPKERTPEPVINVATNKQPLSPAAVQTSLAFRGSPDKPHSLPQPVDVGSRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q312</accession>
    <name>E3Q312_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">General alpha-glucoside permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_00135</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ24991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008090820.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q312"/>
    <dbReference type="GeneID" id="24405500"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00135"/>
    <dbReference type="eggNOG" id="KOG0637">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018303_1_1_1"/>
    <dbReference type="OrthoDB" id="28755at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008506">
        <property type="term" value="F:sucrose:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19432:SF35">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 45 MEMBER 3 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19432">
        <property type="entry name" value="SUGAR TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13347">
        <property type="entry name" value="MFS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="246"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="307"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="359"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="424"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="448"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="529"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="561"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="485"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="599"/>
            <end position="624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ24991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="643" mass="69631" checksum="6490BD27F143CFFC" modified="2011-01-11" version="1">MPSSQSHSPRRGRPMPSNSKRASERSPLLLPTSDDDEGSTDGNTILADQEDLQQTKSTWYLILLTISIGGLQIAWSVELSNGSPYLLSLGLSKSLMALVWIAGPLTGTLVQPYVGMKSDNCRLPWGKRKPFMLGGAVATIISLMFLAWTREIVTGILGLFGADIESRAVRNTIICVAVVGIYVLDFAINTVQASIRAFIVDCAPAHQQEAANAMASRITGFGNILGYVAGYINLPTYLWFLGDTQFKVLCAIASIALATTIVVSTTLIKERDPRLEGPPVLGKPGVFSFFTQIFASIKRLPPQIRKVCQVQLCAWVGFFPLLFYTSSYIGEIYVEPYLEANPHMTPEELDRLYERATRIGTFALLINSVVSLLTNVFLPFFVAPTYDSQPIDDLQGDSDSADYDNEKSSWLDKLQIPGFTLKRAWFASLLLFSGAMFCTVIVRTVEAATALIGLVGITWAMTLWAPWAIISAEISRRDAMIRQAKQRQFGPSGDAEGPASPSLDSVADSELNDGEEPDQAGVILGIHNMAIAAPQIIATVGSSVIFRVWQKPRGTPGDHSIAIVLAFGGIAVLVSSFFVASIKESAAMPADAMIVAEEGEGEGAAGSRPGTARSRNKSYEHLPRASIKRATITRNKSFGGAEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q426</accession>
    <name>E3Q426_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Autophagy protein Apg6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_00482</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the beclin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089358.1">
        <property type="nucleotide sequence ID" value="XM_008091167.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q426"/>
    <dbReference type="STRING" id="645133.E3Q426"/>
    <dbReference type="GeneID" id="24405847"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00482"/>
    <dbReference type="eggNOG" id="KOG2751">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024219_3_1_1"/>
    <dbReference type="OrthoDB" id="20368at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034271">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034272">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043548">
        <property type="term" value="F:phosphatidylinositol 3-kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006995">
        <property type="term" value="P:cellular response to nitrogen starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045324">
        <property type="term" value="P:late endosome to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.40:FF:000005">
        <property type="entry name" value="Autophagy protein Apg6, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.40">
        <property type="entry name" value="Autophagy protein 6/Beclin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007243">
        <property type="entry name" value="Atg6/Beclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038274">
        <property type="entry name" value="Atg6/Beclin_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041691">
        <property type="entry name" value="Atg6/beclin_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040455">
        <property type="entry name" value="Atg6_BARA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12768">
        <property type="entry name" value="BECLIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12768:SF4">
        <property type="entry name" value="BECLIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04111">
        <property type="entry name" value="APG6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17675">
        <property type="entry name" value="APG6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Atg6/beclin coiled-coil" evidence="5">
        <location>
            <begin position="154"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="Atg6 BARA" evidence="4">
        <location>
            <begin position="285"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="98"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="205"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="29"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="122"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ25338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="494" mass="54913" checksum="0BA184A8B9DA344B" modified="2011-01-11" version="1">MYCQKCRTPLKLDSSLEDLNPAAYDLLIASSSQQPPRKTPSSRPYHPQDGQRKVLYDRVSQNAPAPTFKRHAGGPSNSAQRDSTMSFIYLTESQVAQPVLSRPETSPANAKIARNAKSASKGQDEQHGGSKAHEMERISKLFEILSARSDIDHPICVECTDMLVEGLQKKLEIASRERDAYVGFLKQVQGDRPSEEDVKAQNDALKKAKEAEAAAMAELLRLEKEKAAVDAEIVALEEESQQLDREEEQFWRERNAFATKLADFQNERDSTNSKFDNDAQLLEKLQRSNVYNDTFCISHDGTFATINGLRLGRLSNKPVDWPEINAAWGHALLLLVTVADKLGYKFDGFEPQPMGSTSKIIRYELPSPSASRLGSHRNAPPPAPKKHVLELFSNGDLPLGLTFMHRKFDNAMVAFLELVRQLGAFVHRQTAANGHPLSLPYKIEGDKIMDVSIKLGIAQDDGWTKACKLTLTCCKFLLAHASNVNTTARAANNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q546</accession>
    <name>E3Q546_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_00957</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089833.1">
        <property type="nucleotide sequence ID" value="XM_008091642.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q546"/>
    <dbReference type="GeneID" id="24406322"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00957"/>
    <dbReference type="eggNOG" id="ENOG502T4E9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_130533_0_0_1"/>
    <dbReference type="OrthoDB" id="5149687at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ25813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="109" mass="12593" checksum="2F224261CF551E02" modified="2011-01-11" version="1" fragment="single">MCNIISYKLPCEHIQTQVNHCPRAPSPSRKDPFNRKTCREVSQRNITFPPPQGYTMPECPLENCPYEKRNRCWNCCWCGKGWNNGGRCSCVMIIDGAEYRCEHICCNAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5D7</accession>
    <name>E3Q5D7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">peptidyl-tRNA hydrolase</fullName>
            <ecNumber evidence="1">3.1.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_01048</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the PTH family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="1"/>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089924.1">
        <property type="nucleotide sequence ID" value="XM_008091733.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5D7"/>
    <dbReference type="STRING" id="645133.E3Q5D7"/>
    <dbReference type="GeneID" id="24406413"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01048"/>
    <dbReference type="eggNOG" id="KOG2255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062456_2_0_1"/>
    <dbReference type="OrthoDB" id="1711136at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:peptidyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1470">
        <property type="entry name" value="Peptidyl-tRNA hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001328">
        <property type="entry name" value="Pept_tRNA_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018171">
        <property type="entry name" value="Pept_tRNA_hydro_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036416">
        <property type="entry name" value="Pept_tRNA_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17224">
        <property type="entry name" value="PEPTIDYL-TRNA HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17224:SF1">
        <property type="entry name" value="PEPTIDYL-TRNA HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01195">
        <property type="entry name" value="Pept_tRNA_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53178">
        <property type="entry name" value="Peptidyl-tRNA hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01196">
        <property type="entry name" value="PEPT_TRNA_HYDROL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0820">tRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ25904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="200" mass="21949" checksum="3A9B2A8DA0713E3B" modified="2011-01-11" version="1">MAVPRFLLISLGNPEPYYNTLHSAGHHALNHLQKLLGPSQPAFHRGRFGGSPCLASIGPKYAMIQSPAVMNVSGKWVAKAWKETLGSRDPTDLSLLLVHDDLEEELGVVKTRKWKSSHRGHNGVKSVNACLRQADYPGSEWARICIGIGRPEEREKATVSNYVLKPMSRQQRSAIEDNAGPGAYECLLAWEERLAAAAGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5S3</accession>
    <name>E3Q5S3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphotransferase enzyme family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_01315</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090191.1">
        <property type="nucleotide sequence ID" value="XM_008092000.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5S3"/>
    <dbReference type="STRING" id="645133.E3Q5S3"/>
    <dbReference type="GeneID" id="24406680"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01315"/>
    <dbReference type="eggNOG" id="ENOG502QQPX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007526_0_2_1"/>
    <dbReference type="OrthoDB" id="191037at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05154">
        <property type="entry name" value="ACAD10_11_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052898">
        <property type="entry name" value="ACAD10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041726">
        <property type="entry name" value="ACAD10_11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47829:SF1">
        <property type="entry name" value="HAD FAMILY PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47829">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="30"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="370" mass="41187" checksum="99D3B3DA5C139C0F" modified="2011-01-11" version="1">MAGRVRHPIDQEALERYINKHVPHIKTPLDIKQFGYGQSNPTYQLTDATSAHFVLRKKPPGKLLSKAAHKVEREHRIIDALGPTDVPVPKAYCLCEDDSVVGTPFYIMEFLDGRIFEDPTMPEASSPEERRALWQAATVTLARLHRVVPGDVGLAGFGKSSGFYDRQIQTWTTICESQAAAVDRETGERVGDLPHFEEMVRFFGDRGRQPRDRATLIHGDYKIDNIVFHKTEPRVIGILDWEMSTVGHPLSDLCNFLHPYFTAERAGRGVFANEGFRPGATPGLPTTEEVVGWYASEAGWQPVAELNWGMAFSLFRLAAVCQGIAARAAQGQASSEQARRFAVTRGPLAEFAWELVGRSREQDGGRASKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q662</accession>
    <name>E3Q662_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RED-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_01454</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090330.1">
        <property type="nucleotide sequence ID" value="XM_008092139.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q662"/>
    <dbReference type="STRING" id="645133.E3Q662"/>
    <dbReference type="GeneID" id="24406819"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01454"/>
    <dbReference type="eggNOG" id="ENOG502RZ6M">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017393_0_0_1"/>
    <dbReference type="OrthoDB" id="3366823at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039896">
        <property type="entry name" value="Red-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012916">
        <property type="entry name" value="RED_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12765">
        <property type="entry name" value="RED PROTEIN IK FACTOR CYTOKINE IK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07808">
        <property type="entry name" value="RED_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RED-like N-terminal" evidence="4">
        <location>
            <begin position="81"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="279"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="14"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="67"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="92"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="171"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="292"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="321"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="354"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="502"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="525"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ26310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="536" mass="59625" checksum="780BBABC850FBCC4" modified="2011-01-11" version="1">MNNEQFRKLLGAESSKSLSPSNGTPQSNASPAASGALGSRQRSSIPMTPRSVGIGNSRNEFARQLAARNQETQPQKKFRTSTPKGSRLAEGYVDRARDRADEEEDDRAKRIKALEEALKNEEIDQATFEKLSSEIAGGDLSSTHLIKGLDFKLLERVRKGEDVYGDKKGGDEEEEVPPEEEVDEAFDKLEETEVQAVEKEKAKKKGQFAPVALAPGRKRTRDQILAELKASREAAKAQQEAALGNKFKKIGAKQQPGTRIERDSKGREVMIIVDEDGHEKRKVRKIQAGADEEQRKEFVPDKDAKPLGMEVPEFYRKKQEEVEEDDNDDIFADAGDDYDPLAGMDDSSDEDSEGEVKDTTEAKDKTEVKDERSADTIAMPPPPRPAQARNYFKDAKTELISSQTLKGPSMSDPAIQAAFKRAAQLNAANRDQDHDEDVEDDQEARARRERHKRMLQSADRDAEDLDMGFGTSRFEDEADFDDAPVKLSEWGNDDDEGDGKGGKSKRKRGPKKRKGDANNAADVLRVMEQRKAASKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6L5</accession>
    <name>E3Q6L5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cysteine-rich transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_01607</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CYSTM1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090483.1">
        <property type="nucleotide sequence ID" value="XM_008092292.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6L5"/>
    <dbReference type="STRING" id="645133.E3Q6L5"/>
    <dbReference type="GeneID" id="24406972"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01607"/>
    <dbReference type="eggNOG" id="ENOG502SVP4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_156676_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028144">
        <property type="entry name" value="CYSTM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12734">
        <property type="entry name" value="CYSTM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cysteine-rich transmembrane" evidence="5">
        <location>
            <begin position="43"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ26463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="97" mass="10477" checksum="247A52A892760C71" modified="2011-01-11" version="1">MSSQDYYNQGGGYPQHPQPSYGPPQGGYPQQGGGYYPQGGQPQMQYQQQPPMQAPQQRKQGGGNCLTACLAALCCCCVIDETCECCAECCECCFDIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6M4</accession>
    <name>E3Q6M4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cyclic nucleotide-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_01616</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090492.1">
        <property type="nucleotide sequence ID" value="XM_008092301.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6M4"/>
    <dbReference type="STRING" id="645133.E3Q6M4"/>
    <dbReference type="GeneID" id="24406981"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01616"/>
    <dbReference type="eggNOG" id="KOG0236">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003182_0_2_1"/>
    <dbReference type="OrthoDB" id="409725at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034618">
        <property type="term" value="F:arginine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015174">
        <property type="term" value="F:basic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034490">
        <property type="term" value="P:basic amino acid transmembrane import into vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07042">
        <property type="entry name" value="STAS_SulP_like_sulfate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000141">
        <property type="entry name" value="Sulfate transporter family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.750.24:FF:000012">
        <property type="entry name" value="Sulfate transporter family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052706">
        <property type="entry name" value="Membrane-Transporter-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43310:SF4">
        <property type="entry name" value="AFR304WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43310">
        <property type="entry name" value="SULFATE TRANSPORTER YBAR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SpoIIaa-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="3" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="254"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="295"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="357"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="392"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="438"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="463"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="601"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="623"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="657"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="11">
        <location>
            <begin position="729"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="10">
        <location>
            <begin position="941"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="62"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="73"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="140"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="157"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="177"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ26472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1057" mass="117207" checksum="F918B02E2378FC17" modified="2011-01-11" version="1">MLLMFSRQNLPNGRFTGTIVISELQSSGADPFLHPRQPPVDSAQYARSVREDTAELASYLLSDKKTGQGPGFLSRQRSQSSALARETATSDNDTSGLIKVKLPSSPDEDVEGIPEDGPSILTNLLKKSPPQSHRDPSFEPQPEALEPLEPLESSGPEPKRTPSAERPRQEARRSATRVANGSTERTPLISRLSSDSFESYNTNGTTDGIDMEGQKQRPRKKWLRGLKDLSVNVEEHVAHIIQVMTSPKSWDRRALWHNAVVAPASCLPAVIVGLLLNVLDALSYGMILFPLGKPIFANLGSAGISIFYVSTIVSQLTFSTGSIFKGGVGSELIEVVPFFHNMAQTITDHIGENQPDAVIATTIVSYAISSMMTGTVFYLMGKFNFGYMVGFIPRHILIGCIGGVGWFLVATGFEVSARMDGSLEYDMDTLHKLFRSDTVPLWVTPLLLAIVLFYSQARGASKYFLPLYIISIPVVFYFFVFSLDALDPDSLRDHGWIFEGPPADEPWWYFYTLYKFHLVEWDAVLECIPAMLALTFFGILHVPINVPALALQSGEDNADLDRELKLHGYSNFISGMAGSIQNYLVYANTVFFMRSGGDSRLAGYMLAALTFGVMIIGPKIIGFIPIMMVGTLIFDLGFELLLEAVWLPRKKLKVAEYLTVIVIVLVMGIYDFVIGIGVGIILAFVSLTIQTSRVSAVRASYTGEIVGSTVRRNPSQHHYLQEVRRQIHIVKLTGFLFFGTVVSVEEKIRALIDDSSFTERPIKYLILDLYHVTGLDYSAGEAFNTISRLLDNKGIVLVLSGKDAESEVGRNLRAMGLGNDNIEVTLLPDLNSALESCENELLKTLYASQEDLRKGSRHAPTANLDVPAKPDRASFDMVINSPRRNHLYEAARNALANTESSGAKKWQSFKEPLRLMLQIFQGLSDKNEDFWFRAVGYFVRKEYTAGTVLFTRGEPAKGFYLVEKGILRADYDLPQGSLTESIVAGTTCGELPFFSETDRTATVTVDRDCIAWRMDKEGWQKLQKDQPDVAQELLRVSLKLTSERMTSITSYILTMAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6S8</accession>
    <name>E3Q6S8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RNAse P Rpr2/Rpp21/SNM1 subunit domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_02386</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the eukaryotic/archaeal RNase P protein component 4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090586.1">
        <property type="nucleotide sequence ID" value="XM_008092395.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6S8"/>
    <dbReference type="STRING" id="645133.E3Q6S8"/>
    <dbReference type="GeneID" id="24407751"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02386"/>
    <dbReference type="eggNOG" id="KOG4394">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079140_1_1_1"/>
    <dbReference type="OrthoDB" id="128536at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005655">
        <property type="term" value="C:nucleolar ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007175">
        <property type="entry name" value="Rpr2/Snm1/Rpp21"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14742:SF0">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14742">
        <property type="entry name" value="RIBONUCLEASE P SUBUNIT P21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04032">
        <property type="entry name" value="Rpr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="31"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="139"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="31"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="158"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ26566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="172" mass="18867" checksum="E72D96E1F2B62E22" modified="2011-01-11" version="1">MAKPKSESLPNRHAYTRVSYLHQAAAYLATVQSPTSDSTTNSSQPGHAPHAVDHERCLETNETVARRFVSDIRAVSLKAQIRPSPSLKQMMCKYCDSLLVEGKTCSTTVENASKGGKKPWADVMVTKCKTCGNVKRFPVSAPRQKRRPFREQKAVEGQDTTPAVSEMSTGAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q758</accession>
    <name>E3Q758_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_02516</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090716.1">
        <property type="nucleotide sequence ID" value="XM_008092525.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q758"/>
    <dbReference type="GeneID" id="24407881"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02516"/>
    <dbReference type="eggNOG" id="ENOG502QR14">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041456_0_1_1"/>
    <dbReference type="OrthoDB" id="69177at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.620:FF:000021">
        <property type="entry name" value="WGS project CABT00000000 data, contig 2.8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF236">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="7">
        <location>
            <begin position="141"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ26696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="258" mass="28315" checksum="55D758EA05D7AF9B" modified="2011-01-11" version="1">MGKPKSGNAAKTKVGVGTNNSSNTKSATPSTPGAPPAWPQFKPPLPVTHLVPDKLGPCPDKVVLIRNFWPKSLCASYVTFLRGLPLITTPGRPKRGDAVRVNDRFQVQDAAFARRLWDETGLRESLGQEDVQGLWGGEVVGLNPNIRIYRYSKGQYFDAHYDDSNNVSLTPDPSAGPVTCKTTWTLLLYLTSSVEGCVGGETVFFPNDRRSAKEEIPVALETGMLLLHKHGDDCMLHEGREVTAGEKWVLRTDLCVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q784</accession>
    <name>E3Q784_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CREG-like beta-barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_02542</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090742.1">
        <property type="nucleotide sequence ID" value="XM_008092551.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q784"/>
    <dbReference type="STRING" id="645133.E3Q784"/>
    <dbReference type="GeneID" id="24407907"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02542"/>
    <dbReference type="eggNOG" id="ENOG502RDU8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056802_1_0_1"/>
    <dbReference type="OrthoDB" id="2138282at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055343">
        <property type="entry name" value="CREG_beta-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37273:SF1">
        <property type="entry name" value="ADL397C-AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37273">
        <property type="entry name" value="CHROMOSOME 8, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13883">
        <property type="entry name" value="CREG_beta-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178253" description="CREG-like beta-barrel domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="CREG-like beta-barrel" evidence="2">
        <location>
            <begin position="42"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ26722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="276" mass="29853" checksum="4FB4FD24B5BA337B" modified="2011-01-11" version="1">MKASALLVGLAATAATAILEPGMPLHLVSNPSPSDADAARIPTSYESAVMGRRILARTKLAELSTVFPAGARSASGGDLSGMPIGLMDYVADCEGGGNPTILAITIATSFKNVRAGSNISLSMHWIPPYPPAKRISLFSSLRNKLFGSSEAAAAASPDTVPYSAANLPRFSLLGYLEKIPVDPVTSLKLAHCFIDKHPDAKYWLPGSPVHESEWVRFVVTSVYWIGGFGDRAYIGWIPLDEWQNVTREEYESIELPGERRGWKEWSADSWFDGVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7H7</accession>
    <name>E3Q7H7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribosome quality control complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_02635</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NEMF family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090835.1">
        <property type="nucleotide sequence ID" value="XM_008092644.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7H7"/>
    <dbReference type="STRING" id="645133.E3Q7H7"/>
    <dbReference type="GeneID" id="24408000"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02635"/>
    <dbReference type="eggNOG" id="KOG2030">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003612_1_1_1"/>
    <dbReference type="OrthoDB" id="207084at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010494">
        <property type="term" value="C:cytoplasmic stress granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022626">
        <property type="term" value="C:cytosolic ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990112">
        <property type="term" value="C:RQC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904678">
        <property type="term" value="F:alpha-aminoacyl-tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140708">
        <property type="term" value="P:CAT tailing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043043">
        <property type="term" value="P:peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.310.10:FF:000003">
        <property type="entry name" value="Zinc knuckle domain containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.310.10">
        <property type="entry name" value="ibrinogen binding protein from staphylococcus aureus domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021846">
        <property type="entry name" value="NFACT-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008532">
        <property type="entry name" value="NFACT_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051608">
        <property type="entry name" value="RQC_Subunit_NEMF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15239">
        <property type="entry name" value="NUCLEAR EXPORT MEDIATOR FACTOR NEMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15239:SF6">
        <property type="entry name" value="RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT NEMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11923">
        <property type="entry name" value="NFACT-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05670">
        <property type="entry name" value="NFACT-R_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05833">
        <property type="entry name" value="NFACT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NFACT RNA-binding" evidence="7">
        <location>
            <begin position="552"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="domain" description="NFACT protein C-terminal" evidence="8">
        <location>
            <begin position="938"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="443"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="705"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1046"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="443"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="724"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="773"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="789"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="842"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="880"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="907"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="1047"/>
            <end position="1067"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00070414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF11923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ26815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1073" mass="118561" checksum="35A57097A9443E78" modified="2011-01-11" version="1">MKQRFSSIDVKVIAHELQESLTTLRLANVYDLSSKILLFKFAKPDNKKQLIIDSGFRCHLTDFTRTTAAAPSGFVARLRKYLKTRRLTSVKQIGTDRILEFQFSDGQYRLFLEFFASGNVILTDTDLRILTLLRNVPEGEGQEPQRVGLKYSLDNRQNYNGVPDLTKERVRAALESSVKKSAATATAGKKIKVKPGDELRRSLATTITELPPILVDHSFQITGFDGKTKPAEILEDDSLLDALLKALTRARSIVEDATSSATSKGYIFAKYRSKADAASDAAPTAEGEETKRSDLLYDDFHPFLPKKFADDPTVKVLEFDGYNKTVDEFFSSLEGQKLESKLTEREAAARRKLDAARSDQEKRIEGLRGAQSINVQKATAIEANVERVQEAMDAMNGLLQQGMDWVDISKLIEREQKRHNPVAEIIKLPLNLAENTITLLLGEEEDIEDDESNYETDSDASDSEDEDNGNSNKQKSDKRLEVDVNIALSPWANSREYHEQKRSAAKKAEKTVQQSVIALKNAEQKIQAELKKGLKTEKAVLQPIRKQIWFEKFIWFVSSDGYLVLGGKDAQQNEMLYKRYLRKGDVYVHADMHGAATVIIKNSPSTPDAPIPPSTLAQAGTLAVCSSSAWDSKAGMGAWWVNADQVSKSAPTGEYLPTGSFMVRGQKNFLPPAQLLLGIGIMFKISEESKARHVKHRLYDGAGLQVSATDKEPGESAADAAEARDEDSDDASDIGSENDEDEKPRGNPLQNVGADEQNDSEEHLTSGESPAEEMDKLNLEEKQTNENSANEEDEPAEGEEAEEKEDEDSDQAATGQTSTPAEPSGAAPSSKASDTAKEKQRPAKRGQKGKAKKIAAKYKDQDEEDREAAEMLYGSARGKNRAEAEAKSKAEREAQLAFQKERRRAQHERQQKETAEHEEIRRLMNEEGVEVLDSDEMGKMTLLDSLVGTPLPGDEILEAIPVCAPWNAMGKFKYKAKLQPGAVKKGKAVKEVFERWKSDSSRKGALDERSQDTEKMWPREVELIKGLKAEESINVVPVGKVRVMVSGGSGGAGGAKGQQQGKGGRGGRGSKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7Q7</accession>
    <name>E3Q7Q7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02090</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ26919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090939.1">
        <property type="nucleotide sequence ID" value="XM_008092748.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7Q7"/>
    <dbReference type="GeneID" id="24407455"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02090"/>
    <dbReference type="eggNOG" id="ENOG502SR5U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091421_1_0_1"/>
    <dbReference type="OrthoDB" id="5383526at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180197" evidence="1">
        <location>
            <begin position="21"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="188" mass="19817" checksum="3C1726075CEA3E1E" modified="2011-01-11" version="1">MKFFAAASLVSGLFATAASAIDLHLEIAGGCSSSGGGWICYNINPNTCCSVNSGVYLGSGSFRAIPVGWNIQCRGHAGPNCGPIREQQDSGGRNYVCLGNGPFGGLGYGFNNRKMIRGETLDARDVEKTEECAQPDVLYLADGTQYNYTAIAEAGQANEEIVSLIGAGASADDIPSYKEFKLDERLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7R9</accession>
    <name>E3Q7R9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Autophagy-related protein 17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_02102</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize preautophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Preautophagosomal structure membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ATG17 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ26931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090951.1">
        <property type="nucleotide sequence ID" value="XM_008092760.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7R9"/>
    <dbReference type="STRING" id="645133.E3Q7R9"/>
    <dbReference type="GeneID" id="24407467"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02102"/>
    <dbReference type="eggNOG" id="ENOG502SAME">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028356_0_0_1"/>
    <dbReference type="OrthoDB" id="1937984at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990316">
        <property type="term" value="C:Atg1/ULK1 kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030295">
        <property type="term" value="F:protein kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007240">
        <property type="entry name" value="Atg17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045326">
        <property type="entry name" value="ATG17-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28005">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28005:SF1">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04108">
        <property type="entry name" value="ATG17_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0072">Autophagy</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Autophagy protein ATG17-like" evidence="9">
        <location>
            <begin position="60"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="490"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="322"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="508"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ26931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="523" mass="58228" checksum="CAD077B3F58D5CC3" modified="2011-01-11" version="1">MANSPSHRSPASSTSAGRDSGSLSHSRDRRDVPSATSADALVDPVPVETLVEHLLAAKRSLSSITAVLRANEIATDARQAHEEAVVLYAETQFLQRAISDQLALLIKVRRGLKRTYDAGKRDFKNLVKTMDATNEKLQDTMAMLKNTTVEPVFRPPGEGRRNLMDFVDEKSVHVMVEALKQSLGELQSIQTSFDGDLLRFDDDLRLLKKTIAVSPLPRAPSDPSAYDPIPEHLASLVDHSHSMAQLLTSLTKHFDLCVTAVRTTEGGAALARRRAAEATQSQGGDSVSISGVIADQESHMPDLDPITSQDRADMLEIVVSDASEVDSVMQELNERLQAMEEEFAAMTQQTEQIKAAFLGTLDAFTALEDMGGRMASYIASEAEFLQRWEDERYTIYNKLGEMDDLRDFYEKYSNAYDNLILEVERRRMVEDKISTIWKKAKDSVDKLMENDRREREGFRQDIGEYIPTDLWPGMDGGMKRWELVAVDDGAAEDDASGGQRSTPALDRSIVDAARDRLDRSQQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7Y3</accession>
    <name>E3Q7Y3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Xaa-Pro dipeptidyl-peptidase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_02166</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ26995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091015.1">
        <property type="nucleotide sequence ID" value="XM_008092824.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7Y3"/>
    <dbReference type="STRING" id="645133.E3Q7Y3"/>
    <dbReference type="ESTHER" id="colgm-e3q7y3">
        <property type="family name" value="Xaa-Pro-like_dom"/>
    </dbReference>
    <dbReference type="GeneID" id="24407531"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02166"/>
    <dbReference type="eggNOG" id="ENOG502RZEK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048587_1_0_1"/>
    <dbReference type="OrthoDB" id="2498029at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050261">
        <property type="entry name" value="FrsA_esterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000383">
        <property type="entry name" value="Xaa-Pro-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22946">
        <property type="entry name" value="DIENELACTONE HYDROLASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22946:SF9">
        <property type="entry name" value="POLYKETIDE TRANSFERASE AF380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02129">
        <property type="entry name" value="Peptidase_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xaa-Pro dipeptidyl-peptidase-like" evidence="2">
        <location>
            <begin position="29"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ26995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="324" mass="35164" checksum="3ABC026BD88EA114" modified="2011-01-11" version="1">MPLDETVKKIDVEIMGYTIEDRLITSSRDGLKIAISIYQPDGSKRPMPTIVMGHGIEAIKAAGLSPFAGEFTSEGYAAVTFDYISFGESEGSPRNVFNVTHQLQDFQDVIKWVREPEQSSWVDSSRVVAWGSSFGGMHVTALMAEDHDLAAGIAQCPLVDGLAGVLQMPLVRSLRLAAVATADIVGSYLWGAKEPRYVNLVSDGSTPAVMASQEAAEGWVRLAPDNGEDLPTVIAGRSLLSIMLSRPLLQIQKSTRPYLVVLPTWDHEVSLDAAEECVRRAPLGEALRVGGGHFDLYKGGVAYEKNIAGQKQFLRRVLGTLADY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8A1</accession>
    <name>E3Q8A1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pre-mRNA-splicing factor 18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_02284</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PRP18 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091133.1">
        <property type="nucleotide sequence ID" value="XM_008092942.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8A1"/>
    <dbReference type="STRING" id="645133.E3Q8A1"/>
    <dbReference type="GeneID" id="24407649"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02284"/>
    <dbReference type="eggNOG" id="KOG2808">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039675_1_0_1"/>
    <dbReference type="OrthoDB" id="10261918at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071021">
        <property type="term" value="C:U2-type post-spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000350">
        <property type="term" value="P:generation of catalytic spliceosome for second transesterification step"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.940.10:FF:000008">
        <property type="entry name" value="Related to potassium channel regulatory factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.940.10">
        <property type="entry name" value="Functional domain of the splicing factor Prp18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.110">
        <property type="entry name" value="Pre-mRNA processing factor 4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004098">
        <property type="entry name" value="Prp18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014906">
        <property type="entry name" value="PRP4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036285">
        <property type="entry name" value="PRP4-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039979">
        <property type="entry name" value="PRPF18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13007">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13007:SF19">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02840">
        <property type="entry name" value="Prp18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08799">
        <property type="entry name" value="PRP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00500">
        <property type="entry name" value="SFM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47938">
        <property type="entry name" value="Functional domain of the splicing factor Prp18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158230">
        <property type="entry name" value="PRP4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Pre-mRNA processing factor 4 (PRP4)-like" evidence="9">
        <location>
            <begin position="125"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="51"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="51"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ27113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="347" mass="39944" checksum="4F891B246997851C" modified="2011-01-11" version="1">MDFAALMSKELDKAKESTPASSSSKYVKRADVEAKRRQEYLAEQARIEAEREARAAAKRKREDEEAAEKKIREEKRQKLAEESRRRREEKEAEEERARRKRLGLPELVKASSEDVAEVEDGMEDIPDEELAGKLRALGEPATLFGEGHVARLRRYRRLTTVVTKGPIPTTLQLVDEKDMKVDGTVPKDKEGRSWLFRQLASYFTMVLTEYEKAMEQERRDTTASKTAYSAMVQSRENLKPLFRKFEKHDLDDDLLAPVVEIVKAAQERRYVDANDGYLRLSIGKAAWPIGVTMVGIHERSAREKLHNGERGHVMGDEVTRKYLQSIKRLLTFAQIRWPPTDVRQLMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8B1</accession>
    <name>E3Q8B1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02294</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091143.1">
        <property type="nucleotide sequence ID" value="XM_008092952.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8B1"/>
    <dbReference type="STRING" id="645133.E3Q8B1"/>
    <dbReference type="GeneID" id="24407659"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02294"/>
    <dbReference type="eggNOG" id="ENOG502SGBF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027580_0_0_1"/>
    <dbReference type="OrthoDB" id="5422351at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40625:SF1">
        <property type="entry name" value="AMP-ACTIVATED PROTEIN KINASE GLYCOGEN-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40625">
        <property type="entry name" value="GTP-BINDING PROTEIN ESDC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="214"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="311"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="411" mass="45729" checksum="F288CB45658C4A73" modified="2011-01-11" version="1">MERDIRRDRSQWRGCYAFKDIVLDDEPGAKNTKRNGGLKMGNTYYYYYELDGTQESHNPAQPTTTQCPYLPGQTVNRLDMPYEMAERKRSASLGSLYNSEYKTMNPEDKFVTPRPPPPVPGGQLRRLGSAPAAQPQRSLPRSGSTSPPPSWRRMFNRKPSTSRFAERGRHSDDEERPLSPSSPSDDNRSMVSSEGSRTRDLSPESLRRFLSDDSPFAAASPSPYGRASVAIPDDIAEENDDDENFANSALSEINPYATSLSPPPFKRCHSDSTLPTVRRTSVLTREKKYSPLPPLPVKELRELEIAPPASRFSFSSDSSAASSVGPVSPEDEATSFYDSAEEDRCPNYIQPLSLPSTRKPALEQNYSLPRAPGIKRHPGVHTVLAAPPEHALDDLTHDMGWMVDIIRAKGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q924</accession>
    <name>E3Q924_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02033</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091558.1">
        <property type="nucleotide sequence ID" value="XM_008093367.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q924"/>
    <dbReference type="GeneID" id="24407398"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02033"/>
    <dbReference type="eggNOG" id="ENOG502RKIA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_167703_0_0_1"/>
    <dbReference type="OrthoDB" id="3551791at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179529" evidence="1">
        <location>
            <begin position="18"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="118" mass="12365" checksum="074EACA5443C4AEE" modified="2011-01-11" version="1">MLVKTFLLMNLGAFASAQTFLGFPESLTCKTDNGPATISETECQNAIVGPKGLKQDDSAANVASGHCSTLSGIPLFVESVAGKGDVGFAFDKSKNTYYFCFGQGVIDESGYPSSCTEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9J2</accession>
    <name>E3Q9J2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Tat pathway signal sequence</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_01866</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Mycotoxin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ustYa family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091391.1">
        <property type="nucleotide sequence ID" value="XM_008093200.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9J2"/>
    <dbReference type="GeneID" id="24407231"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01866"/>
    <dbReference type="eggNOG" id="ENOG502RKCP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042941_0_2_1"/>
    <dbReference type="OrthoDB" id="3687641at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043386">
        <property type="term" value="P:mycotoxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365:SF4">
        <property type="entry name" value="CYCLOCHLOROTINE BIOSYNTHESIS PROTEIN O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365">
        <property type="entry name" value="YALI0B05434P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="264"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ27371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="294" mass="33528" checksum="27D34E68DEF7275E" modified="2011-01-11" version="1">MWLKLRRDYDSLPQSEGMGGEINSQSARSFNHLFSRSTVALGFTNVITLVALFLVINATHSKDEIAELCTREFSTISPAFEAVKYKAPDHYNAEFRQTNKWRGPPGTHSNEVDIAWHEIELGAGGIRVTKEEVKLLNMTDSPEMPFHEIPEEQGGGYLAMLEVFHLLHCLNSLRMGLFYNYDHYKFLDEGVPDENIYSHFDHCIDMLRMNLQCQADVTPALFVDPLDNPLRRDALPSWSSMHTCRDFDAILDWNKNGPRSVRWRDAGANPSWDPTLEGAEEPFPPEAVDEGHHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9K7</accession>
    <name>E3Q9K7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">polynucleotide adenylyltransferase</fullName>
            <ecNumber evidence="3">2.7.7.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_02690</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the poly(A) polymerase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.19" evidence="3"/>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091566.1">
        <property type="nucleotide sequence ID" value="XM_008093375.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9K7"/>
    <dbReference type="STRING" id="645133.E3Q9K7"/>
    <dbReference type="GeneID" id="24408055"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02690"/>
    <dbReference type="eggNOG" id="KOG2245">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004292_0_0_1"/>
    <dbReference type="OrthoDB" id="10263155at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990817">
        <property type="term" value="F:poly(A) RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1140.10">
        <property type="entry name" value="Cyclic phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040459">
        <property type="entry name" value="MJ1316"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011068">
        <property type="entry name" value="NuclTrfase_I-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007012">
        <property type="entry name" value="PolA_pol_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002934">
        <property type="entry name" value="Polymerase_NTP_transf_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10682">
        <property type="entry name" value="POLY A POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10682:SF23">
        <property type="entry name" value="POLYNUCLEOTIDE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13563">
        <property type="entry name" value="2_5_RNA_ligase2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04457">
        <property type="entry name" value="MJ1316"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01909">
        <property type="entry name" value="NTP_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04928">
        <property type="entry name" value="PAP_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55003">
        <property type="entry name" value="PAP/Archaeal CCA-adding enzyme, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="14" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="14" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="11">
        <location>
            <begin position="249"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="domain" description="Polymerase nucleotidyl transferase" evidence="10">
        <location>
            <begin position="634"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="domain" description="Poly(A) polymerase central" evidence="13">
        <location>
            <begin position="760"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="domain" description="MJ1316 RNA cyclic group end recognition" evidence="12">
        <location>
            <begin position="1117"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1065"/>
            <end position="1114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="1065"/>
            <end position="1087"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ27546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1198" mass="134528" checksum="FF6DAE076E632D5A" modified="2011-01-11" version="1">MDFPVAATHDTALCLIPPRDQWSSVDRLRCDNDKAYTKWPPHVNLVYPFVKSTDPSALRLACDAIVDSLISRTTLGEAAALPIRLDSADYFQHKNGSTLFLCDKDVGRVSQIASLRADILAAIGQTRSGLYNMHMTVIQCEDTAPSSKLEFLLEKLRRLPPVSWNAGQLAVLVRTPSGQMKQWGLIDLASPSLQLCEDSFGLDQDTTATASPQQTWYISDHHPTWRPVDPVFSEPPSLTVKGSENLIVASWNVLAEFRWPPSRARYPIILDNLLAETSLADVVVLQEVTDDFLPYLLEDERIRKQYAYVSHGPPDNPAAGPLPNLLNNVVLSKYIFSWEYLPFKRQHKGSCVVRLDGLGHGESEGLSLPLILATCHLSQGLTDGAVVAKERELQRILSHLKSNYAANQWLIAGDFNIATSSCTVDNAVKKGSITVQTEAVLRRIEVTLAEAGLLDAWMVSRIEAGVTDNLKGNDNDIFEGEQGATFDPRENPHAAKMVGSGYNNRPQRYDRILVKSEGPLQISRFNMFGFIMGEGGPGEGPLYASDHWGIRCLLQRFDSRGAAVTSARVVPVQPKKAPAGLSDTAALRQCMENLEVFPTEQDETTRKEALQLLRQILLDSDQANADQTRGRPTVMLVPVGSYGLGTWSRTSDIDCLCIGSISPRIFFTLARQRLRKSGESGVRLLRKVKAKTGTMLEVEVMGIKCDLQYCQAPSVVDQWPDMLKRPPSDPAFSLPMQTLLKLKPARDLFYLQRSIPDLAQFRVSFQAIKTWAKSRGIYAAKFGYLGGIHLSVMLVKVCKMLLRVGGVVSAVDIITTFFDHYSRFDWQNDVVFDPFFHKNLRYHRTPREAMCLLGWHSPTLNTALIASVPTVKIISAELCHAATQLSGDGASWQSLLSIPDSSQDRNMTPSASKFLGSYRSFVNLRIHYWGASLERGSRLVGWLESRCASLLVDINRRVPELSARIWPARFVDSLTPEADETRGDYQGSYLIGLDWMNSDEKPSRDDLETAQSNLWAVLQQFEKLIVSDEKYFDPNTSWFSATVVKANELGNLQLDDREWGVYVDGDDESETEDEEEEEEEEGEDEEMQERFAEKTKKGKSIKQRSATSRKPEGAGKLRSALDVLNRLRWDPDMDSNDFLVGYEDRFLGPQEKALSAWKSEQTHEEFIPQHRILWFKRRSDDVIVWHRSERIDLLFKKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9W5</accession>
    <name>E3Q9W5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Thioesterase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_02797</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioesterase PaaI family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091673.1">
        <property type="nucleotide sequence ID" value="XM_008093482.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9W5"/>
    <dbReference type="STRING" id="645133.E3Q9W5"/>
    <dbReference type="GeneID" id="24408162"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02797"/>
    <dbReference type="eggNOG" id="KOG3328">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089876_1_1_1"/>
    <dbReference type="OrthoDB" id="2831072at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047617">
        <property type="term" value="F:fatty acyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03443">
        <property type="entry name" value="PaaI_thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039298">
        <property type="entry name" value="ACOT13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21660:SF1">
        <property type="entry name" value="ACYL-COENZYME A THIOESTERASE 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21660">
        <property type="entry name" value="THIOESTERASE SUPERFAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="3">
        <location>
            <begin position="77"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ27653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="175" mass="19038" checksum="342D87B348E2A7D1" modified="2011-01-11" version="1">MSGEIPAKFKPVFDAKTGEERIKAWLTLDKDDAGNFESGSWMSALSPSISLISASLTPTPSATFAFTVRPEHCNRAGNLHGGAAATLFDSLTTMPLALINDRPGYWQFLGVSRTLSCSYLRPAPAGEECIVECEIVQVGRLMCHLRGTLRRKRDGSVLATCEHHKFNTDPPASKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9Z2</accession>
    <name>E3Q9Z2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_02824</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091700.1">
        <property type="nucleotide sequence ID" value="XM_008093509.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9Z2"/>
    <dbReference type="STRING" id="645133.E3Q9Z2"/>
    <dbReference type="GeneID" id="24408189"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02824"/>
    <dbReference type="eggNOG" id="KOG0730">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000688_12_3_1"/>
    <dbReference type="OrthoDB" id="27435at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001025">
        <property type="entry name" value="ATPase family, AAA domain-containing 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF27">
        <property type="entry name" value="ATPASE FAMILY GENE 2 PROTEIN HOMOLOG A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="248"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="514"/>
            <end position="660"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ27680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="766" mass="83865" checksum="AECC4F0FA9A427A3" modified="2011-01-11" version="1">MAKTIDGKVRPLAPFDKTLEKATLKGASRIYVNRDALIQLTGSIDNGRRCIVTRTAAQDATKSAAELRREAALWTLSDKNISPNIILMSEAYREACGFDLGDHVTITMCEKSAVPDAETVNVLPMTTSEREKADISAWEGAWIGVIRFYLARAEQVFPGMKFECVASGVKQTFRITTVDGQTDNVARYVVSTVTRIVLGEGEEPVQEVVRDVKRLVVSNIPGLHAEEQKLRSFFRGFNTNLVYKGQQKSCGIVIHGGRGTGKSYILSRIAATGWGRVFRIEENDKSSTVEEVFKQARTMQPSIVLIDGLQALIGKDRANSTAIIQRLGQQLDQLAEDALKNGTLPKVVVVATCLDYMTDVPPELQKRTRFERNIALSIPNAEGRLEILKSFDIPIQPEIKDAMLDKLAQQTHAFNASDLDRLIENSMMISAERLDPDEAGYDEETMGTPYLSREDLEQALRSTRPTAMHDVNLKPPTIHWQDVGGQESLKSALRNMITLTTTNDPGVQKLILTPPKGLLLYGPPGCSKTLSAQAMATESGFNFFAVKGAELLNMYVGESERAVRQLFERARAASPSIIFFDEIDSIGGQRAGGAGGGGGAAAAKSQGSVNMLTTLLTEMDGFEALSGVLILAATNRPEAMDPALLRPGRFDRIVYVGPPDAAGREAVFNLYLRKLPLAPDIDVAELSRLSEGFSGAEIKQIVNVATEPALSKALNRTTAGKEGEQARVCMEDIVQAIQLVPKGITRQMLDGYDKWSKQFMKHQNQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QA11</accession>
    <name>E3QA11_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02843</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091719.1">
        <property type="nucleotide sequence ID" value="XM_008093528.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QA11"/>
    <dbReference type="GeneID" id="24408208"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02843"/>
    <dbReference type="eggNOG" id="ENOG502S621">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047721_0_0_1"/>
    <dbReference type="OrthoDB" id="5370011at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="60"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="350" mass="38870" checksum="5F998919B574C50B" modified="2011-01-11" version="1">MSSPAQAGPSVPKEKKGFGKILSRAKTVFKRGDGSSKRMSTLSTAGQQPPSQTITPGQSTAPATEQPAAAATTTKETNEAPKSKYEDLPGVVRIPRAELFEERARKLGERFGLEIKQSEWISTEGTALRVEKPIRMRVHRTCHKCNATFGAAKECPGCQHSRCTKCVRHPPKRTEAERIASREKRAAILKAQKENPPIVPDYSYDLKDTKDIVLKRPSKTGGQDLIYKKPRQRIRRTCHECQTLFTAGSKTCSKCNHNRCTDCPRDPPKKDKYPFGYPGDEFGPNAVPHHECHKCKTIYPGGAADGTACKKCEHEKCGDCPRLKPRKVEPEPDPEILKSIQAKIESLKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QA76</accession>
    <name>E3QA76_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glutathione-dependent formaldehyde-activating enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_02908</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091784.1">
        <property type="nucleotide sequence ID" value="XM_008093593.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QA76"/>
    <dbReference type="GeneID" id="24408273"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02908"/>
    <dbReference type="eggNOG" id="KOG4192">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055491_0_0_1"/>
    <dbReference type="OrthoDB" id="2993351at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052355">
        <property type="entry name" value="CENP-V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28620:SF1">
        <property type="entry name" value="CENP-V_GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28620">
        <property type="entry name" value="CENTROMERE PROTEIN V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="4">
        <location>
            <begin position="13"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="CENP-V/GFA" evidence="4">
        <location>
            <begin position="151"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ27764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="294" mass="32636" checksum="AFF70F7075A2B539" modified="2011-01-11" version="1">MATSEEQEPKRTYRGNCHCAAFVYEFEATEIKSLSECNCSICVKKGALWITPPRDNFRFVKGAENELFSYKFGSGQMIHKFCGNCGTAVMVDFPNGPPYMKMALNARSIQDIDIVGLEKRSVNGASWGSKYEVPAHKGPNPTAEVEGGKLYTGSCHCGAVTVAVTSKPIDETYEDTIIECNCSICVRNAYIWLKPGADQVVLSGDDSNIGRYTFSHRILAKTFCKTCGVPLTNQYNPLTEEERDALTKDARYWHDWSKDKHPVNARVLNGVDLKSLKVHHADGKAEFLPGYVNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAC1</accession>
    <name>E3QAC1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Telomere-associated protein Rif1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_02953</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Telomere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091829.1">
        <property type="nucleotide sequence ID" value="XM_008093638.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QAC1"/>
    <dbReference type="GeneID" id="24408318"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02953"/>
    <dbReference type="eggNOG" id="ENOG502QSZW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000830_2_0_1"/>
    <dbReference type="OrthoDB" id="5399929at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140445">
        <property type="term" value="C:chromosome, telomeric repeat region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022031">
        <property type="entry name" value="Rif1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22928">
        <property type="entry name" value="TELOMERE-ASSOCIATED PROTEIN RIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22928:SF3">
        <property type="entry name" value="TELOMERE-ASSOCIATED PROTEIN RIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12231">
        <property type="entry name" value="Rif1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0779">Telomere</keyword>
    <feature type="domain" description="Telomere-associated protein Rif1 N-terminal" evidence="8">
        <location>
            <begin position="154"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="91"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1128"/>
            <end position="1177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1213"/>
            <end position="1477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1493"/>
            <end position="1698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="59"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="122"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1128"/>
            <end position="1140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1141"/>
            <end position="1152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1153"/>
            <end position="1168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1253"/>
            <end position="1267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="1294"/>
            <end position="1305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1325"/>
            <end position="1334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1352"/>
            <end position="1361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1399"/>
            <end position="1412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1413"/>
            <end position="1428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1529"/>
            <end position="1547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1585"/>
            <end position="1605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1636"/>
            <end position="1652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1668"/>
            <end position="1678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1687"/>
            <end position="1696"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ27809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1772" mass="195965" checksum="57C29356568324B0" modified="2011-01-11" version="1">MGSVEVVSSRLESLPPRPPTPPRETSQAADATLAPKHFIVLPPSSDPRASLHTPPSGCSPLSGTDSTNPSVRRARKRVGFSAKAQYNEAPHYQGVNVSGKRSPLSVPSSTQPKPVKGILKQTSSPSPLSTSTKADGLTASVNISDMLESTVKQLAGADRDSKRDAYSTLVNALKTSNNLPDRIALQVKMGLFVQFIQRDITAKNPASSGPDAPLVNDALRLLATFLHFPAIASTIPSDFGVFFIDHCIRSFENPSTPKDIARHLMHAVATQDFSPKVMTSDRVRRLVAALRNIEDILKGKSIVMSRILIYKRLVQQSKQLMVLHSDWLNDLLTDMLSRVKELRSAAISLGFEAVYTFGKEKSLSRKVMELFDTSIEEMKFAEYYHQQLRSMAKDKDDRQLTAAVPKIWSVIILFLRCPLDRWQFFNQWLQLIQMGFNNNDHPQTKQEANFAWNRFVWSMHTEGQSFAKLLPTLYQPLGSQLKSKYTSKHIREVVFGSVCNLLYYTFKPGTSTTLLESYWDACVKPITEAPKAHARNADAVDEHLRQATLILTGLFDSTTPRLWREERIRETPLARPHELPAIDPKWLRRNSSRVFQVIEPIMEKHFLELSDKNSRIHCLWRTLVGAMVSAASKEIKVSVDTTAFISQMCGLLLKRWEAGLTEIKYLSPETATRFLASAGELITVTVEALGPLPFTEKMISLGRLQNFTPVSTPSHKPAKNAGDARTPLQHLAGLMSRLPPGIADNEEFVDFYRTVFNPFFAPRSAKSRFDLAQEMLSATPIWSSAVTHSPYAPWVIAAECLASIFSSSQNNVQTTSSTGEPALGHEYRTVVRLLERGWQEAPNLPWQHWRFLLTALSNRASEETGEAGRALGVIEPLAKAIHESIPADSTSLVSAKTVTAAAELLSIAKHPLDRQAVEAARRRLWGTAVTGSKSSSFDPFNNLYKLTNELLERLYEANESDNMDDSATLLKECGGFLSRCNVELAPRTVSNLESGLVMWIRDSQGIIKARQSPATSEAAKALWDAVRGIILPDTTPAEIQLEAFEELFCAAFESKHRHIVNSIAQAWNCIYENAESIQYPEHLKTVLLAVRPTVDIILPGLESTRETATDENHSFVESQDDIEMLTVSSTRSSRNRPINFSSPLSSTKASLSARKKLGSTPRRTRSGGRRSAATARLRHDDSQIQFAPIENSPLNPAVNPESQVLTERQKEIRERQKDTVAMFPAMRSSPQAQTEEDASVELKAVVPESVPETSKDVTPKRSVRYEDFVSSTPTPRRGQAVAMADNDQDMTDPPSSPPEPRPFPLLPQIKSRTSSRSELDDWHFSSSPVSGSPSLEMAIVTDEPTELHLTNADASLRQSGEASPDLSAVDDSFQGVPSSAVEEPELPPPVLEKAKETLQPQQSEQATTETTSVPQPDSTPSTPKNTRVINVEEPRSGNEVFVDAPSSPQPTVLTRSATRAAVNKDRSFEMSDGDETSMLRLVVDLDRRRCELPISKYPATSPPKPSKGPRNGKQRKGKPAVLDCITVCGEDDDDEEEEEEEDEDEPAELAPSQPQTAPHESKSRSPGKPSTPVTRSAASPPDKSAKKRKRGGASRYGTRYKKRKSTAGEADDETNEMETSQLAMSPVLGEEAFCESQHSFTGDTPSKLSTGSRSEDLEAEIHSQLVHEQQEADHRESQSFEAPNLEPSLTQTQLTAEDSMDVDVADTTNAVIAQPKPQAQVDTKDVRMVDSLSSVLDQLRSAALSRDEVYKMEDILMDIKRELFAAEARGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAC8</accession>
    <name>E3QAC8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SprT-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_02960</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091836.1">
        <property type="nucleotide sequence ID" value="XM_008093645.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAC8"/>
    <dbReference type="STRING" id="645133.E3QAC8"/>
    <dbReference type="GeneID" id="24408325"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02960"/>
    <dbReference type="eggNOG" id="ENOG502T51F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099915_0_0_1"/>
    <dbReference type="OrthoDB" id="4837982at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ27816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="237" mass="26740" checksum="7F89F306DE38E26B" modified="2011-01-11" version="1">MPGSSSELRPHGQYGAYYIDDLVTRSIQHGLSLDAEDAVDAKDKLKYALIEGLHELYDSQSQEHLDHMLEVARVVDQYFLQGWLTHTHRRPSGQEIAYLRIDIRDGNENCEDSCSSFRVGVQSDGVGSLPVVDVDIEAAGAWTIGRIVEMMIHEMVHGYLLLFSCRGGSCQEFGVCSQYSHDKRGRHGCHSRTLLKHIYESIQEWDDALGGFGEDFIDGCDQERQDDVLVDVRNLYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAK4</accession>
    <name>E3QAK4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_03036</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ27892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091912.1">
        <property type="nucleotide sequence ID" value="XM_008093721.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAK4"/>
    <dbReference type="STRING" id="645133.E3QAK4"/>
    <dbReference type="GeneID" id="24408401"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03036"/>
    <dbReference type="eggNOG" id="ENOG502R95R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039071_0_1_1"/>
    <dbReference type="OrthoDB" id="4828117at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="361" mass="39124" checksum="211313528F9C76B5" modified="2011-01-11" version="1">MAPANFKTYEAQARLLRAIVAAHPEVKWNYKDIQKFYGSDMTKDALNHRFRAIRNHTWTLQQATYQGVDCKDIPVDLPKEKKEIAKFFGESTADGIQFQFRGIKKDAESLKQTANSGGNPATALNLPASATSSAFSTPRKPRTPSTKTRVSGGGRSTTAKKTKQLKPAPISVSEEDEEEDEDVDYNELEDTPSKSRIRDHILDGRVSKNRHTPNPRRSATPSRAATIAAAANIAQAAAVDLTTSDSEVNTPDNSVGYQLPAAVDMKPAIMQQQAQVQSIFGSPASAYEQSIVQPVAQPVIQPAAQPAIHPVSNSSYSGHSSFDPSQSVSVFNDDPLNFSFIDSMGHGGGDFDPYTGNDGEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAS5</accession>
    <name>E3QAS5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_03107</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ27963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091983.1">
        <property type="nucleotide sequence ID" value="XM_008093792.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAS5"/>
    <dbReference type="STRING" id="645133.E3QAS5"/>
    <dbReference type="GeneID" id="24408472"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03107"/>
    <dbReference type="eggNOG" id="ENOG502SN89">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042940_0_0_1"/>
    <dbReference type="OrthoDB" id="3220769at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="434"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ27963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="453" mass="50416" checksum="32210DF2C112F3ED" modified="2011-01-11" version="1">MHRSWFSYPITKPYPFRWFTPVVVIGGLVLAVLLSLANLSANGFYLKSVYISDPNATEDSANGLWYRKPPFNWQSDVQAECQPRLLSVGDSFFTSNQGFRYTVEAIEDSAKRSQPAVRYKNNFLRDCVPTTINIKLRKVDTAAPSWWISWLESTAEATVSCGVVTDDGLVTITLATTGVGRGDRKLLNTYWSGVMSVASQMSLRDRYVVRAGLTFNTKPSENDIQTDTFFDLYWWMTHNDSLIANKGFAENITDYNSKFYGSPTFTEGLHYAKILYSLLSLDLGSCQLPSLLLDEDGLRYAILAPDDLNRVRGGLLNDSFTVRVMDSDRYKTIPSPGDDGTGGDQIDLKESYRLIRPLTGPLGCSNATVVTQYLCSVPQQKGWGVLLFSILLADLVFLQAAWKILTWVSDGIVARQNPEAMSCQSHSIQSESYELVDGSKVPHQAAKPSSEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAU8</accession>
    <name>E3QAU8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_03130</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ27986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092006.1">
        <property type="nucleotide sequence ID" value="XM_008093815.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAU8"/>
    <dbReference type="GeneID" id="24408495"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03130"/>
    <dbReference type="HOGENOM" id="CLU_2426886_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ27986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="91" mass="9905" checksum="CF705E8F3EF235BC" modified="2011-01-11" version="1">MQSRLPLATAKKDEKKSIYLAATNYILAQFMRRATPSKDWAHVTKLISFCPLPDRVLWPVRSLRLGEVDAHVREGGWPGSASAGGIGGSLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QB55</accession>
    <name>E3QB55_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribonucleases P/MRP subunit Pop8-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_03237</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ28093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092113.1">
        <property type="nucleotide sequence ID" value="XM_008093922.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QB55"/>
    <dbReference type="STRING" id="645133.E3QB55"/>
    <dbReference type="GeneID" id="24408602"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03237"/>
    <dbReference type="eggNOG" id="ENOG502SCWV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115053_0_1_1"/>
    <dbReference type="OrthoDB" id="5530243at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005655">
        <property type="term" value="C:nucleolar ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000172">
        <property type="term" value="C:ribonuclease MRP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000171">
        <property type="term" value="F:ribonuclease MRP activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004526">
        <property type="term" value="F:ribonuclease P activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034965">
        <property type="term" value="P:intronic box C/D snoRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000294">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, RNase MRP-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020347">
        <property type="entry name" value="Pop8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049128">
        <property type="entry name" value="Pop8-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28173">
        <property type="entry name" value="RIBONUCLEASES P/MRP PROTEIN SUBUNIT POP8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28173:SF1">
        <property type="entry name" value="RIBONUCLEASES P_MRP PROTEIN SUBUNIT POP8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20976">
        <property type="entry name" value="Pop8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribonucleases P/MRP subunit Pop8-like" evidence="2">
        <location>
            <begin position="35"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ28093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="148" mass="15893" checksum="4380DE7DB07B8359" modified="2011-01-11" version="1">MTMQNSSTGEASSSAPRGTGQRSHELLTCTIKTPPYSYVRLELVVDSPQLHEAAEGLDNIQVRSYCTAALRQFLGATGSAIPVDILKVDGNQCWLRVPRPDLSPFAAAITAWAGVTEQGGRRVLQVKQCSDYLGAMAGAEGQDKLWSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBF9</accession>
    <name>E3QBF9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_03442</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092318.1">
        <property type="nucleotide sequence ID" value="XM_008094127.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBF9"/>
    <dbReference type="GeneID" id="24408807"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03442"/>
    <dbReference type="HOGENOM" id="CLU_2256390_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ28298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="104" mass="12178" checksum="1032AF50C21E8165" modified="2011-01-11" version="1" fragment="single">RVMEKAVRVHHSTQYSSRTRLKVRLCCDSFCHCVQTRKRDRKSKNITKGSPWHVYPPPPGNPTPAYMSRSKRVAVRRANKDSWKPREKLPTLFCFTNHTPPQAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBJ6</accession>
    <name>E3QBJ6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C-1-tetrahydrofolate synthase, cytoplasmic</fullName>
            <ecNumber evidence="8">1.5.1.5</ecNumber>
            <ecNumber evidence="7">3.5.4.9</ecNumber>
            <ecNumber evidence="6">6.3.4.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">GLRG_03479</name>
    </gene>
    <organism evidence="24">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>(6S)-5,6,7,8-tetrahydrofolate + formate + ATP = (6R)-10-formyltetrahydrofolate + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20221"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:195366"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.5" evidence="8"/>
    <dbReference type="EC" id="3.5.4.9" evidence="7"/>
    <dbReference type="EC" id="6.3.4.3" evidence="6"/>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092355.1">
        <property type="nucleotide sequence ID" value="XM_008094164.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBJ6"/>
    <dbReference type="STRING" id="645133.E3QBJ6"/>
    <dbReference type="GeneID" id="24408844"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03479"/>
    <dbReference type="eggNOG" id="KOG4230">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003601_2_0_1"/>
    <dbReference type="OrthoDB" id="5126881at2759"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004329">
        <property type="term" value="F:formate-tetrahydrofolate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004477">
        <property type="term" value="F:methenyltetrahydrofolate cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004488">
        <property type="term" value="F:methylenetetrahydrofolate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009257">
        <property type="term" value="P:10-formyltetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006555">
        <property type="term" value="P:methionine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00477">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01080">
        <property type="entry name" value="NAD_bind_m-THF_DH_Cyclohyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000006">
        <property type="entry name" value="Bifunctional protein FolD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000245">
        <property type="entry name" value="C-1-tetrahydrofolate synthase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001123">
        <property type="entry name" value="C-1-tetrahydrofolate synthase, cytoplasmic isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10860:FF:000005">
        <property type="entry name" value="C-1-tetrahydrofolate synthase, cytoplasmic, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.770:FF:000001">
        <property type="entry name" value="Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.410.10:FF:000001">
        <property type="entry name" value="Putative formate--tetrahydrofolate ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.410.10">
        <property type="entry name" value="Formyltetrahydrofolate synthetase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10860">
        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01543">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01576">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000559">
        <property type="entry name" value="Formate_THF_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020628">
        <property type="entry name" value="Formate_THF_ligase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000672">
        <property type="entry name" value="THF_DH/CycHdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020630">
        <property type="entry name" value="THF_DH/CycHdrlase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020867">
        <property type="entry name" value="THF_DH/CycHdrlase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020631">
        <property type="entry name" value="THF_DH/CycHdrlase_NAD-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48099:SF5">
        <property type="entry name" value="C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48099">
        <property type="entry name" value="C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01268">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00763">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02882">
        <property type="entry name" value="THF_DHG_CYH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00085">
        <property type="entry name" value="THFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00721">
        <property type="entry name" value="FTHFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00722">
        <property type="entry name" value="FTHFS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00766">
        <property type="entry name" value="THF_DHG_CYH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00767">
        <property type="entry name" value="THF_DHG_CYH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 23" id="KW-0436">Ligase</keyword>
    <keyword evidence="19" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="17" id="KW-0521">NADP</keyword>
    <keyword evidence="13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="18" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic" evidence="21">
        <location>
            <begin position="6"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding" evidence="22">
        <location>
            <begin position="143"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00012859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00017592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00049033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF00763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF02882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="EFQ28335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="939" mass="100782" checksum="9354340F85115253" modified="2011-01-11" version="1">MVANKIDGTAIAKQIRDSIASDVLEKQKLNPRFQPQLTIIQVGERSDSSTYVRMKQKAAKEANVDCELIQFPESITESELLDRIYRLNDNPAVHGILVQLPIPKHLDEYVITSAVADEKDVDGFGTRNIGELAKKGGRPFFIPCTPKGVMVLLQEAGVDLKGKNAVVLGRSDIVGSPVSYLLRNADATVTVCHSKTEGLEEHLKAADVVVAAIGQPGFVKGEWLKPGAVVIDVGTNYIPDPSKKSGQRLVGDVDYESASQVASHITPVPGGVGPMTVAMLLSNVVDSTVKSFERQKQRKISPLPLHLKEPVPSDIEVSRSQNPKQITRLAKEVGIASHELEPYGAYKAKVDLSLLKRLEHRRNGKYVVVTGITPTPLGEGKSTTTMGLAQALGAHLGRVTFANVRQPSQGPTFGIKGGAAGGGYSQVIPMDEFNLHLTGDIHAITAANNLLAAAIETRMFHENTQKDGPLYKRLVPAKNGKRVFAPVMLPRLKKLGIEKTNPDDLTEEEIRRFARLDIDPETITWRRVLDVNDRHLRGITVGAAPTEKGHTRETGFDISVASECMAILALSTDLADMRKRLGSMVIASSRSGDPVTCDDIGAGGALTALMRDAIKPNLMQTLEGTPVFVHAGPFANISVGNSSILADKMALKIVGTEPEEDHSEKAGFVVTEAGFDFTMGGERFFNIKCRASGLVPDVVVVVATVRALKVHGGGPPIAPGAPLNAVYKQENVDILRAGCVNLKKHIQNAKMYGIPVVVAINKFVTDTDAEIAVIREEAIAAGAEDAILSNHWAEGGKGAFELGKGVIAASEKPKDFKLLYDLEGSVQQRIEAIGQKMYGAAAVEFSELAQKKVDTYTKQGFGNLPICVAKTQYSLSHDPDLKGAPTGFTVPIRDVRMAAGAGYLYALAADIQTIPGLPTAPGYLNVDVDTETGEIDGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBQ9</accession>
    <name>E3QBQ9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thioesterase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_03542</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092418.1">
        <property type="nucleotide sequence ID" value="XM_008094227.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBQ9"/>
    <dbReference type="STRING" id="645133.E3QBQ9"/>
    <dbReference type="GeneID" id="24408907"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03542"/>
    <dbReference type="eggNOG" id="ENOG502S411">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101141_0_2_1"/>
    <dbReference type="OrthoDB" id="2420454at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047617">
        <property type="term" value="F:fatty acyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00586">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.129.10:FF:000104">
        <property type="entry name" value="Thioesterase family protein (AFU_orthologue AFUA_2G16350)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050563">
        <property type="entry name" value="4-hydroxybenzoyl-CoA_TE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31793">
        <property type="entry name" value="4-HYDROXYBENZOYL-COA THIOESTERASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31793:SF27">
        <property type="entry name" value="NOVEL THIOESTERASE SUPERFAMILY DOMAIN AND SAPOSIN A-TYPE DOMAIN CONTAINING PROTEIN (0610012H03RIK)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13279">
        <property type="entry name" value="4HBT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ28398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="157" mass="18220" checksum="BE08ECFED2C74035" modified="2011-01-11" version="1">MTSYAELKQRRREDYRYMLDYRTRWADNDMYQHMNNSIYNFLYDSVVNTYLIEHCRLSPAGSKQHGVVVHSHSDYFASISFPAVAELALRVNKLGKSSVTYEIALFEKGVDQVRAVGEFVHVFVERSTGRPTASGMTDEMRRGLERIQVVEARENKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBU6</accession>
    <name>E3QBU6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">CorA-like Mg2+ transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_03325</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092201.1">
        <property type="nucleotide sequence ID" value="XM_008094010.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBU6"/>
    <dbReference type="STRING" id="645133.E3QBU6"/>
    <dbReference type="GeneID" id="24408690"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03325"/>
    <dbReference type="eggNOG" id="ENOG502SMU8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034568_0_0_1"/>
    <dbReference type="OrthoDB" id="5428055at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="452"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="483"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ28181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="555" mass="63076" checksum="5D08EE77D4BA5FB8" modified="2011-01-11" version="1">MEKACAWLAGGDYEDFVRSLSFMDPRLRQRDPKAQTQRIPFTDDGARVVKLSLENGTFARTAEFDEPAGLEAHFRSTASLRGRRDIYVVEGLGPGFAGVLGERFSLHPSFFVEHERVVVHSLNWMGESDGVQLPSVIQSRGHLEMKYYEVVAFDRKPTSFRWVCAATGRHIGVSRDFKWDNSPDEVGNYLNVGVVRRKCGVWSRRTEGGGWDCLVLCDPPVKSVRTGDEYKREYPVKACPYQGGYLDFVPEEEQIRVAREGRYCGPPRISMLEDLSFYLETHSRLVDIAEPESVNVFVKKIVASHFLKQSEHLRATLSAVQRGLTRKQDLAKMPMNKVEALWSDMQGWERRTGEYLEDLEGIMLQLGIPLSHPVPPALVNMPPARPGALTAETIAWQDCTADFQFLYLRFRELRHRTETLNAAVTGLASITGNRQGYKEQQRSIREAKSTKAVTLLGLVFVPLAYTCSLFGMEVPYGPGGEYFWIYFVTSAPLILVVLLGYYILDFGYNDDGRAWSVVTFNKSINERLYRLKRQDTEEIIRDTSRIEMSKLEACQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QC32</accession>
    <name>E3QC32_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">tRNA (uracil-O(2)-)-methyltransferase</fullName>
            <ecNumber evidence="4 12">2.1.1.211</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_03411</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.</text>
    </comment>
    <comment type="function">
        <text evidence="1">Probable adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>uridine(44) in tRNA(Ser) + S-adenosyl-L-methionine = 2'-O-methyluridine(44) in tRNA(Ser) + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:43100"/>
            <dbReference type="Rhea" id="RHEA-COMP:10339"/>
            <dbReference type="Rhea" id="RHEA-COMP:10340"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74478"/>
            <dbReference type="EC" id="2.1.1.211"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the TRM44 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.211" evidence="4 12"/>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092287.1">
        <property type="nucleotide sequence ID" value="XM_008094096.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QC32"/>
    <dbReference type="STRING" id="645133.E3QC32"/>
    <dbReference type="GeneID" id="24408776"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03411"/>
    <dbReference type="eggNOG" id="KOG3790">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018580_2_0_1"/>
    <dbReference type="OrthoDB" id="10047021at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141101">
        <property type="term" value="F:tRNA(Ser) (uridine(44)-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002128">
        <property type="term" value="P:tRNA nucleoside ribose methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011671">
        <property type="entry name" value="tRNA_uracil_MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21210">
        <property type="entry name" value="TRNA (URACIL-O(2)-)-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21210:SF0">
        <property type="entry name" value="TRNA (URACIL-O(2)-)-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07757">
        <property type="entry name" value="AdoMet_MTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 12" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="8 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="10 12" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="67"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="70"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU368004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ28267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="503" mass="56384" checksum="F63B3669927AF711" modified="2011-01-11" version="1">MAYNPTALGQSAEPLVHDVSGEVWHPLWEQECVFGPDVFEDVMMNLVKNPNINSSWLFRADILHDSDPAWTPPPPPPPPPTSDTPEEDDAAQAVRQPVPVAFRDFHIHRLLVRRLIPRNTRRDDPLDQTCVFASCTPDATKTRSLVVYLPHVSSPDDLPFYHPKVRGVAHLHEWDAARAVGTVSIHYLLYDESDLAVDKLLRTARMLLQALWKHGQGRVQGYTKRVHHDLVIPQARFQDRYTELKLKYAKDLVENWAETTDPSKHVFEDLGIAAFLTELWADMYKDRPFPGFVDIGCGNGLLVHLLIREGYSGWGFDARARKSWAKYNSVQNGRHSLQALVLLPDVVSGPSYAQGEEPVLDLAKIHNGAFPKGTFIVSNHADELTPWTPILATLSESPFIMIPCCSHGLGGQKYRPPPPRDKTKSQSTYASLVDWAAQIAEDCGWLVETEMLRIPSTRNTAMLGRERTRPVEEVNIDGVLAKYGGTAGYFESAAKLTKTEKGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCW5</accession>
    <name>E3QCW5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RNA polymerase Rpb4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_03881</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the eukaryotic RPB4 RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092757.1">
        <property type="nucleotide sequence ID" value="XM_008094566.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCW5"/>
    <dbReference type="STRING" id="645133.E3QCW5"/>
    <dbReference type="GeneID" id="24409246"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03881"/>
    <dbReference type="eggNOG" id="KOG2351">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110332_0_0_1"/>
    <dbReference type="OrthoDB" id="2186918at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030880">
        <property type="term" value="C:RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.40:FF:000003">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit rpb4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006590">
        <property type="entry name" value="RNA_pol_Rpb4/RPC9_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045222">
        <property type="entry name" value="Rpb4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005574">
        <property type="entry name" value="Rpb4/RPC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038324">
        <property type="entry name" value="Rpb4/RPC9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21297">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03874">
        <property type="entry name" value="RNA_pol_Rpb4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00657">
        <property type="entry name" value="RPOL4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="HRDC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA polymerase Rpb4/RPC9 core" evidence="5">
        <location>
            <begin position="27"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ28737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="144" mass="16214" checksum="0D3463A646497DB0" modified="2011-01-11" version="1">MSHHAPTSRPKPPPPGSEEASTILNLGEFQHVDTLTLSEASLVINALVTKRKMDRKNINETEMLTQTLNYLDAFSRFRQKENVEAVERLLSAHKQLAKFERAQIGSLCCETAEEAKTLIPSLQDKISDDDLQILLDEISKLQSR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2011-05-31" modified="2025-04-09" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDN5</accession>
    <name>STS1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName>Tethering factor for nuclear proteasome STS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">STS1</name>
        <name type="ORF">GLRG_04117</name>
    </gene>
    <organism>
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates. Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Binds the proteasome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cut8/STS1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ28973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092993.1">
        <property type="nucleotide sequence ID" value="XM_008094802.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDN5"/>
    <dbReference type="SMR" id="E3QDN5"/>
    <dbReference type="STRING" id="645133.E3QDN5"/>
    <dbReference type="EnsemblFungi" id="EFQ28973">
        <property type="protein sequence ID" value="EFQ28973"/>
        <property type="gene ID" value="GLRG_04117"/>
    </dbReference>
    <dbReference type="GeneID" id="24409482"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04117"/>
    <dbReference type="eggNOG" id="ENOG502RNK4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033658_0_0_1"/>
    <dbReference type="OrthoDB" id="10061064at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071630">
        <property type="term" value="P:nuclear protein quality control by the ubiquitin-proteasome system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031144">
        <property type="term" value="P:proteasome localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1590:FF:000001">
        <property type="entry name" value="Tethering factor for nuclear proteasome STS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1590">
        <property type="entry name" value="Tethering factor for nuclear proteasome Cut8/Sts1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013868">
        <property type="entry name" value="Cut8/Sts1_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038422">
        <property type="entry name" value="Cut8/Sts1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28032">
        <property type="entry name" value="FI02826P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28032:SF1">
        <property type="entry name" value="FI02826P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08559">
        <property type="entry name" value="Cut8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0539">Nucleus</keyword>
    <keyword id="KW-0653">Protein transport</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <feature type="chain" id="PRO_0000409409" description="Tethering factor for nuclear proteasome STS1">
        <location>
            <begin position="1"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="20"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="48"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="276"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="308" mass="33980" checksum="8369543B2287C183" modified="2011-01-11" version="1">MNVLLSPQPPLFQHPHETNRISPSRSLSPFHNMSTSRKRKADEDGDEMSMSPRSSPAASSRQLQRPSKKVRSNELVGRPLTLPRLLETLDPTALRTVLERICERHPDIGQEVVNSAPRPTVAAAHGVLQEYQDKMKAAIPYGETSPDYTYYRVKAPMTALIDALLDFTPQYLPPNETQTTVSLQYMDGATKIIHALPDWEPQQYRHHKENAYDEISKAWALVINEAAKRGGGLSLHTGGWDQTLAKHHEISGGRMGTAMNAMATSVSWMAHGGSSNGQQPGNPSSDQNSILNQLMSGTYGAPVRVGPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QE58</accession>
    <name>E3QE58_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">KilA-N domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_04290</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EFG1/PHD1/stuA family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093166.1">
        <property type="nucleotide sequence ID" value="XM_008094975.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QE58"/>
    <dbReference type="STRING" id="645133.E3QE58"/>
    <dbReference type="GeneID" id="24409655"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04290"/>
    <dbReference type="eggNOG" id="ENOG502QW2C">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016460_0_0_1"/>
    <dbReference type="OrthoDB" id="5407653at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048315">
        <property type="term" value="P:conidium formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030435">
        <property type="term" value="P:sporulation resulting in formation of a cellular spore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.260.10:FF:000003">
        <property type="entry name" value="Ascospore maturation 1 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.260.10">
        <property type="entry name" value="Transcription regulator HTH, APSES-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029790">
        <property type="entry name" value="EFG1/Phd1/StuA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036887">
        <property type="entry name" value="HTH_APSES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018004">
        <property type="entry name" value="KilA/APSES_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003163">
        <property type="entry name" value="Tscrpt_reg_HTH_APSES-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47792">
        <property type="entry name" value="PROTEIN SOK2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47792:SF1">
        <property type="entry name" value="PROTEIN SOK2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04383">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01252">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54616">
        <property type="entry name" value="DNA-binding domain of Mlu1-box binding protein MBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51299">
        <property type="entry name" value="HTH_APSES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0183">Conidiation</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0749">Sporulation</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH APSES-type" evidence="10">
        <location>
            <begin position="191"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="95"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="304"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="60"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="373"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="416"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="432"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="525"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="578"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="605"/>
            <end position="620"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ29146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="707" mass="75510" checksum="FC5CFB5081CB2FB9" modified="2011-01-11" version="1">MNSERIPSLPLPTPHQAYSSGTSSPRVSSIGSASSQHAGSQSSFTSAASSNGPKTPSPTLPINSAIPGSSSQSIGGYDHYPAMNQPAADMYYSQHMSAGQAPPPQTVTSGNMSYHQPPPLQPSHLPQYTQQTQYGQPYGYTNGLTSPQNAPPAVNNGMGGQNVLPLPGVSTQGFQGFDTTGQVAPPGMKPRVTATLWEDEGSLCFQVEARGICVARREDNHMINGTKLLNVAGMTRGRRDGILKSEKVRHVVKIGPMHLKGVWIPFERALDFANKEKITELLYPLFVHNIGALLYHPTNQTRTNQVMAAAERRKQEQSQMRGAPQTGGPGLPSIQQHHHHSMGLPGPQQSLPSHANMGRPALDRAHTFPTPPTSASSVMGGSMGTSDNGFQWAQSQNMGTAQAQNPMSIDTGLSNARSMPATPASTPPGSTIQNMQSYQQSGTQQYDNSRPMYNQSAQQSPYQTTNQAPQDRAVYGQSDPYAKNDMGPPSARPATSGAPQDQKPTNGIMHPDQSASQPAGEEEAEHEHDAEYTHDSGAYDTNRGSYNYSAPAVGTLPAEHQHLSPEMTGSPGHPPPSGRATPRTAAAPQPYYSQQAGYNTPPRVAQQSSSNLYNVMSNDRGSAAAGANDVYQPQADMGPMSNGYPSQINGSSGGIKRGRDDDDDLQRPLSGGGMDLKRRKTLMNSAVPAYDTMARAAPVMTQQPQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QED1</accession>
    <name>E3QED1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_04381</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093257.1">
        <property type="nucleotide sequence ID" value="XM_008095066.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QED1"/>
    <dbReference type="STRING" id="645133.E3QED1"/>
    <dbReference type="GeneID" id="24409746"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04381"/>
    <dbReference type="eggNOG" id="KOG0005">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010412_6_4_1"/>
    <dbReference type="OrthoDB" id="428577at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01806">
        <property type="entry name" value="Ubl_NEDD8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000023">
        <property type="entry name" value="NEDD8 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038738">
        <property type="entry name" value="Nedd8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019954">
        <property type="entry name" value="Ubiquitin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050158">
        <property type="entry name" value="Ubiquitin_ubiquitin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10666">
        <property type="entry name" value="UBIQUITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00299">
        <property type="entry name" value="UBIQUITIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ29237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="77" mass="8570" checksum="3D3F3A89D48A73CC" modified="2011-01-11" version="1">MLIKVRTLTGKEIELDIENEYKVSQIKEKVEEKEGIPPVQQRLIYGGKQMVDDKSASEYGLEAGATLHLVLALRGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEU9</accession>
    <name>E3QEU9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">tRNA (guanine(37)-N1)-methyltransferase</fullName>
            <ecNumber evidence="10">2.1.1.228</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">M1G-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">tRNA [GM37] methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">tRNA methyltransferase 5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">TRM5</name>
        <name evidence="13" type="ORF">GLRG_04549</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>guanosine(37) in tRNA + S-adenosyl-L-methionine = N(1)-methylguanosine(37) in tRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36899"/>
            <dbReference type="Rhea" id="RHEA-COMP:10145"/>
            <dbReference type="Rhea" id="RHEA-COMP:10147"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="EC" id="2.1.1.228"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Mitochondrion matrix</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="10">Predominantly in the mitochondria and in the nucleus.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the TRM5 / TYW2 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.228" evidence="10"/>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093425.1">
        <property type="nucleotide sequence ID" value="XM_008095234.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEU9"/>
    <dbReference type="STRING" id="645133.E3QEU9"/>
    <dbReference type="GeneID" id="24409914"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04549"/>
    <dbReference type="eggNOG" id="KOG2078">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022610_2_2_1"/>
    <dbReference type="OrthoDB" id="408788at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052906">
        <property type="term" value="F:tRNA (guanine(37)-N1)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070901">
        <property type="term" value="P:mitochondrial tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002939">
        <property type="term" value="P:tRNA N1-guanine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.110:FF:000001">
        <property type="entry name" value="tRNA (guanine(37)-N1)-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.110">
        <property type="entry name" value="Met-10+ protein-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03152">
        <property type="entry name" value="TRM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030382">
        <property type="entry name" value="MeTrfase_TRM5/TYW2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056743">
        <property type="entry name" value="TRM5-TYW2-like_MTfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056744">
        <property type="entry name" value="TRM5/TYW2-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025792">
        <property type="entry name" value="tRNA_Gua_MeTrfase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23245:SF36">
        <property type="entry name" value="TRNA (GUANINE(37)-N1)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23245">
        <property type="entry name" value="TRNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02475">
        <property type="entry name" value="TRM5-TYW2_MTfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25133">
        <property type="entry name" value="TYW2_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51684">
        <property type="entry name" value="SAM_MT_TRM5_TYW2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="SAM-dependent methyltransferase TRM5/TYW2-type" evidence="12">
        <location>
            <begin position="141"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="318"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="332"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="270"/>
            <end position="271"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="298"/>
            <end position="299"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="353"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ29405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="459" mass="51949" checksum="171C94B1E796989C" modified="2011-01-11" version="1">MAKQDSDMINLRAPLARAATILDRSLFSKKLELAAATVKDPRNISKYRKQLEKSKELLTLDRLDSCRNDPKAPGLKCLLLRPDVKADAPTTWGPVFQEGVKAGDLDVVPYELDLDYDYWSYLDVMTSVLPEELHVEIPVGFNTAGHVAHLNLKDQYLPYKKIIAEVILDKNPKIRTVINKIDDVGHESVFRTFAYEVLCGPHDLNVEVKENDCIFQFDYSKVYWNSKLEPEHTRLISKFKAGEVVADVMAGIGPFAVPAGRKGVFVFANDMNPESYKYLSAAVEKNKVTQYVRPYNMDGRKFIQEAVHQVYDASKRGEGAVIKPKQSRSKPQNPPPEPKRVPIPPTISHFVMNLPASAYTFVKHYKGIYRGHEKLFEPYTSAKLPMVHVHCFALKSDDEVPLNDILERIYAEIGVRLKLGDADKYGEVDIYNVRDVAPKKRMYCASFRIPPEVAFAADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3QF79</accession>
    <name>E3QF79_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04661</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093537.1">
        <property type="nucleotide sequence ID" value="XM_008095346.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QF79"/>
    <dbReference type="GeneID" id="24410026"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04661"/>
    <dbReference type="HOGENOM" id="CLU_2305879_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="100" mass="11468" checksum="EE12B4800C85F544" modified="2011-01-11" version="1">MLPRARRLGTLTPPSPSASPFALRGQGGLVRDWGGKKLREKRTRRGRRMRRCAELCFASILSRNMVSLKERRKKKTKCCPKTLPNAITALFFYFTLLKTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFS6</accession>
    <name>E3QFS6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04905</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093781.1">
        <property type="nucleotide sequence ID" value="XM_008095590.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFS6"/>
    <dbReference type="STRING" id="645133.E3QFS6"/>
    <dbReference type="GeneID" id="24410270"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04905"/>
    <dbReference type="eggNOG" id="ENOG502SQ74">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038389_0_0_1"/>
    <dbReference type="OrthoDB" id="5383784at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="302"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="527" mass="58894" checksum="F7660C8EE4F772FF" modified="2011-01-11" version="1">MTRLGPLTAQALGRSPFDDVVDGEGETDPRAPTQQYDNRGRPINPETKRMNRDMVRSHNEVMQVIGVAEPDNAPPSAEVESIRRYSNYEDAVGTRLLRFGRALEIAGVWGINGMRLRILLYKRYADISFFELLQHERKQRSLSSALLTGLPTFLGGHVFKMATYWVYPFPRKNHYINTALSYIRVHLQLYVFLQRLDIIPSSKMFPSLSFFIPGSPSSPIAAPAPPKDFSASSLAQYAGAWCVNAIPFVSYVIWGQIWTEVTGHLWQEFYGRLPNTVHHRKPPPRLPPPSAPILETPEPVPDIDRSHPEPLSEIGHADPTEDIPPEVDSPIEPPIQAVRRPSAFSARGDDYGSDDEEDGGVSATLISFDVEATDSTDAPPGLWSAELRPSTGPEGSGHGASVQYMDTMLTRLPACLASDIFTVISGYVLVSPYEAVALRLVARSYRERMGLPTFDIHDTNIFSGMTLRGVTNFLGLEFVHLVIAGELWALITGLAQWFHLTEEEWKLFNEIEEAEAAEERRRQEQQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFT9</accession>
    <name>E3QFT9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Malic enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_04918</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="7">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="7">Divalent metal cations. Prefers magnesium or manganese.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the malic enzymes family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093794.1">
        <property type="nucleotide sequence ID" value="XM_008095603.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFT9"/>
    <dbReference type="STRING" id="645133.E3QFT9"/>
    <dbReference type="GeneID" id="24410283"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04918"/>
    <dbReference type="eggNOG" id="KOG1257">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011405_5_2_1"/>
    <dbReference type="OrthoDB" id="5365701at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004471">
        <property type="term" value="F:malate dehydrogenase (decarboxylating) (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05312">
        <property type="entry name" value="NAD_bind_1_malic_enz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000182">
        <property type="entry name" value="NAD-dependent malic enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10380">
        <property type="entry name" value="Malic enzyme, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012301">
        <property type="entry name" value="Malic_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037062">
        <property type="entry name" value="Malic_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012302">
        <property type="entry name" value="Malic_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001891">
        <property type="entry name" value="Malic_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010052">
        <property type="entry name" value="PRK13529.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23406">
        <property type="entry name" value="MALIC ENZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23406:SF32">
        <property type="entry name" value="NADP-DEPENDENT MALIC ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00390">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03949">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000106">
        <property type="entry name" value="ME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00072">
        <property type="entry name" value="MALOXRDTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01274">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00919">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Malic enzyme N-terminal" evidence="9">
        <location>
            <begin position="125"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="Malic enzyme NAD-binding" evidence="8">
        <location>
            <begin position="315"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="219"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>(S)-malate</name>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="291"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="463"/>
        </location>
        <ligand>
            <name>(S)-malate</name>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="512"/>
        </location>
        <ligand>
            <name>(S)-malate</name>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ29774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="624" mass="69865" checksum="3D3A862619BF1A37" modified="2011-01-11" version="1">MSISSRRMTDFNPMSAVDISAIEEKMRMAALDQHRGYAQNTFGEVQQYRTTEYVPKTQATAYQVLSEPLWNKGLSFTPEERVNKNLTGLIPHTMESLQTQCQRAMKMINTRQTDVDKYLYLSSIKAQNFDLFYRLLIDNIRELMPLVYTPTIGDVCLQYSTLYTRPEALYISIKQRKSIRTMLRNWPYPNPQICVVTDGSRILGLGDLGVNGVGISIGKLALYTGAAGIHPENTLPIVLDTGTNNEGNLKDPFYLGIRSKRVPVPEQQAFMDEFMEAVTEVYPNMTVQFEDFESEKAFNYLDRYRNKYRCFNDDIQGTGAVVLAGYINAVELSGVPIEEQRLVFMGAGSAGVGVAKQLVEYYTKRGISEQAAKDKFWLVDTKGLVTKDRGDKLAEHKKYFARTDNNGHQFRSLEEVIEYVKPTALIGLTATFGVFTESVVRALKASVDSGGLGRRPVLFPLSNPLTKAECTFEQAVQWTDGTVIFASGSPFSPFTMKTPDGHAVTYHPNQGNNVYVFPGLGLGAILAKASKITDDMVYTSAAALAAGLTADEIHKGLIYPRIERVRDASVLVAREVMKSARRDGVSTLPESQWIEWEEWGDVALDAWIKERVYDPVSFSEKSRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGX4</accession>
    <name>E3QGX4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Threonine aspartase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_05256</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ30112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094132.1">
        <property type="nucleotide sequence ID" value="XM_008095941.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGX4"/>
    <dbReference type="STRING" id="645133.E3QGX4"/>
    <dbReference type="MEROPS" id="T02.004"/>
    <dbReference type="GeneID" id="24410621"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05256"/>
    <dbReference type="eggNOG" id="KOG1592">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021603_5_2_1"/>
    <dbReference type="OrthoDB" id="77601at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04514">
        <property type="entry name" value="Taspase1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.30:FF:000007">
        <property type="entry name" value="Similar to threonine aspartase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.30">
        <property type="entry name" value="(Glycosyl)asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000246">
        <property type="entry name" value="Peptidase_T2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037464">
        <property type="entry name" value="Taspase1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188">
        <property type="entry name" value="L-ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188:SF8">
        <property type="entry name" value="THREONINE ASPARTASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01112">
        <property type="entry name" value="Asparaginase_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="268"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="205"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="268"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="400"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="2">
        <location>
            <begin position="399"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ30112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="584" mass="62515" checksum="26D7605B4902476F" modified="2011-01-11" version="1">MEHLVTETKDDTALAAEGSPTLSLQGPHIRVSGNHAKTMGGANGTVDRMLKRMQKGKFGGAIFIHAGAGFHSHQNERVHLEACSNAASMGMKFLKSGASATEAVEAALRILEDKEITNAGYGSNLSMDGTVECDATIVDHLGRSGACGAVPNIRNPVCLAKLILDKSSQPLSLRRVPPNILVGEGAKNFAMENGMQVVPNDYLISKNARDRFLRWQEDLNRAEERLRQARARKPPGEAIDNCQQHETMPIPARLHQNQQRDHANAILSGTWNEGQPDSPQRGSPALEQMQGHHQGNPLAGSAYPRTPPQQIERSPLSYIGVSAPSANRSRPTILQEKDSLVAPPSQLANEGSRDGTRSPQWTDGAKFASTIAQLQGCSPRSLKRPFSATELEHEDVITDTVGAIAIDEKGNIAAGSSSGGIGMKHRGRIGPAALVGIGTAVVPCDPNDPDKISVATVTSGTGEHMATTMASQRCAERIYGNTRRGPNGRDVEEWDEDAIMESFITNDFMGHPGVKGCSSAGAIGVMTVKKTRTGYYLYFAHNTDSFALASMGGSDREPVCVMSRLGETAQVTRGARRIRVDPGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QH14</accession>
    <name>E3QH14_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Necrosis inducing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05320</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697348">
        <property type="protein sequence ID" value="EFQ30176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094196.1">
        <property type="nucleotide sequence ID" value="XM_008096005.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QH14"/>
    <dbReference type="STRING" id="645133.E3QH14"/>
    <dbReference type="GeneID" id="24410685"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05320"/>
    <dbReference type="eggNOG" id="ENOG502SS8U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062263_0_1_1"/>
    <dbReference type="OrthoDB" id="89086at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008701">
        <property type="entry name" value="NPP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33657">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33657:SF6">
        <property type="entry name" value="SECRETED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05630">
        <property type="entry name" value="NPP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179723" evidence="1">
        <location>
            <begin position="20"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="280" mass="31606" checksum="A781787487894E05" modified="2011-01-11" version="1">MFTGTLLVAWGLLWTATAASPIGHGISKTAMKHAFPLKINECAPEADKKWQPALDFDTDSCYNTPAVDRDGTLNAGMGVCETWSTAGRCRDRSDLENSNVYSRARCNNGWCAYMYGYYFEKDQISPCLGHINDWEHVVVFVRDGVPEYVSASAHGRYERRAWRDLFADGTHAKIVYHKDGPGTHAFRFAKAADDMRQENHHESWFYGDLIGWNGFPSTAVRDKMTSKSWGKAKIDFTDERFKDSLELAIVGRGREPRDIDMRTDVDDGSPGMSVYCPKYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHK0</accession>
    <name>E3QHK0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Frag1/DRAM/Sfk1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_05482</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697349">
        <property type="protein sequence ID" value="EFQ30338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094358.1">
        <property type="nucleotide sequence ID" value="XM_008096167.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHK0"/>
    <dbReference type="STRING" id="645133.E3QHK0"/>
    <dbReference type="GeneID" id="24410847"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05482"/>
    <dbReference type="eggNOG" id="KOG3979">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009808_0_0_1"/>
    <dbReference type="OrthoDB" id="68581at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.10.10:FF:000031">
        <property type="entry name" value="Calcofluor white hypersensitive protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019402">
        <property type="entry name" value="CWH43_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057315">
        <property type="entry name" value="Exo_endo_phos_PGAP2IP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051916">
        <property type="entry name" value="GPI-anchor_lipid_remodeler"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053912">
        <property type="entry name" value="PGAP2IP_TM_1nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053911">
        <property type="entry name" value="PGAP2IP_TM_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14859">
        <property type="entry name" value="CALCOFLUOR WHITE HYPERSENSITIVE PROTEIN PRECURSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14859:SF1">
        <property type="entry name" value="PGAP2-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23022">
        <property type="entry name" value="6TM_1st_PGAP2IP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23021">
        <property type="entry name" value="6TM_2nd_PGAP2IP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23226">
        <property type="entry name" value="Exo_endo_phos_PGAP2IP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10277">
        <property type="entry name" value="Frag1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="283"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="306"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="390"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="422"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="461"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="501"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="526"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="549"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="579"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="614"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="651"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="domain" description="CWH43-like N-terminal" evidence="2">
        <location>
            <begin position="18"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="PGAP2IP first transmembrane" evidence="4">
        <location>
            <begin position="283"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="PGAP2IP second transmembrane" evidence="3">
        <location>
            <begin position="457"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="domain" description="PGAP2IP C-terminal nuclease-like" evidence="5">
        <location>
            <begin position="684"/>
            <end position="923"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ30338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
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    </evidence>
    <sequence length="962" mass="108311" checksum="80B538054D4F321B" modified="2011-01-11" version="1">MSSRYKDKDSGVALTFNGQWISWLHTTTAYSAFISAFIVGVSLHYHKIVQNEWYGYPQEWFPSVSATIGDRYPERSFYMFFIAITSGPRFALVGLWYLLTRRPGQTLPKFTFAMGIMRTVMCGGFTYVTSTDDHDWHDIFMISYIVATLPWTIGCVLLSPPNPQAIKYRKWIASTFFGTLVPLIYFFIQHKVHRVAGAYTIYAFFEWALILLDVAFDAVTALDFSTFEVVIKDVKGATKGDNRSSVPSAVLEKEKEKATAGVLTGRFTWVEALDTAADVYHGFVFWTMLTGLGVCVWYFPLWHMGISGYEAFVMSTILPAILGIRGIRSLVVNNQRIIHLVSLIGLLAYKVVDPANRLFTVGFAVATSCLAWTATLWSERAHQSRLESRILAWTIGLIASSTAKFMWYTNNPLWPVVHAANGGWNATGFAIAVVAALRFTRRSPLTTGDYPGDSQKGGSSLLAAFGVGGLFFGLHSLLSDTSTMILWVWDGYPIRGPTSNTYGWMTIVAMTAGLLMGLYRPGLMSSWTAYGIGCVGAAILTSYHHWFGYYGALTTAVYLMGLSVPFLSNAAKKSPGTTFGLGFFIYNIMVLFHVWVVAYAFVPGGPLVREHTDWVMMTTFLLIGAGVFDLTSSQARRRDTRRSSPSQHKKYNTIAAAFVNVVFLAAAFMRFPTNDYKPYHAEDRIMTAGIWTIHFSLDNDMWSSEYRMRDLIKELEIDVVGLLESDLQRIIMGNRDTTQFLAEDLGMYVDYGPGPNKHTWGSALLSKFPILRSTHHLLPSPVGELAPAIAATLDVYGQEVDVFVFHSGQEEDPEDRRLQTEYLSKLMGESKNPSVLLSYLVTKPLEGNYNTYVSSTSGMHDVDPTDWDRWCEYILYKGLKRTGYARVSRSTITDTELQVAKFVIPRSEDEVQRIEALDDETRNKRVGEEEVPQGWRFPSMFRGQGVRDHRYHVFDEPRYYNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHW6</accession>
    <name>E3QHW6_COLGM</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05598</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EFQ30454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008096283.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="24410963"/>
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    <dbReference type="eggNOG" id="ENOG502T5TX">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2026553_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="122" mass="12286" checksum="04A020B293640CBF" modified="2011-01-11" version="1">MAATAAAMAATAAAAVGGGWNNGGGWNNGGRGQGGGYNNGGGWNNGGGWNNGGGWNNGGGWNNGGGGGSGGNVGTGCPSGQVGAWDSNGNWYCYVPNSDWSNSYRRRRSLNRRPANRNGRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHW9</accession>
    <name>E3QHW9_COLGM</name>
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        <recommendedName>
            <fullName evidence="5">Carbohydrate-binding-like protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="3" type="ORF">GLRG_05601</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697349">
        <property type="protein sequence ID" value="EFQ30457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094477.1">
        <property type="nucleotide sequence ID" value="XM_008096286.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHW9"/>
    <dbReference type="STRING" id="645133.E3QHW9"/>
    <dbReference type="GeneID" id="24410966"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05601"/>
    <dbReference type="eggNOG" id="ENOG502RYBJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022878_0_0_1"/>
    <dbReference type="OrthoDB" id="271448at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36578:SF1">
        <property type="entry name" value="APPLE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36578">
        <property type="entry name" value="CHROMOSOME 15, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178477" description="Carbohydrate-binding-like protein" evidence="2">
        <location>
            <begin position="17"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ30457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="360" mass="38347" checksum="D4ABBAC863AC3CC0" modified="2011-01-11" version="1">MRSALILAAVAGFTTANPVAPRSTTPQGGIDLKIFDAETKPTKVGPAVGASSEKPTYNAAQAQAAAAQDAVENPVAAAKPSVKARDSTCTGSNREPDGYGPVPSPDTYSSFMSSTALSNIASGAVVPQGYSLAFQGLQASVSGPSYQGLYTLRTYDPIQCQQYCDAAPACYSFNLFIERNPKFTPSDTCVDPESITNYKCTLWGAQLSGDAATNQGQWRYQFQVGITGSNGYNKNAPPPSNPGFDAPVAFGGATQAPNSYMGSKYYPGPFDPSQCASACVATTQYDHDHPNSDGTYDACNFFNAYVLSENNVPQGTYCSMYTKPWDKSYSTNYGQWRGNDYYSVSQSYGYTLTVQDSGKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>E3QI19</accession>
    <name>E3QI19_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Vacuolar protein 14 C-terminal Fig4-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_05651</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VAC14 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697349">
        <property type="protein sequence ID" value="EFQ30507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094527.1">
        <property type="nucleotide sequence ID" value="XM_008096336.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QI19"/>
    <dbReference type="STRING" id="645133.E3QI19"/>
    <dbReference type="GeneID" id="24411016"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05651"/>
    <dbReference type="eggNOG" id="KOG0212">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007740_0_0_1"/>
    <dbReference type="OrthoDB" id="5574975at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070772">
        <property type="term" value="C:PAS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006661">
        <property type="term" value="P:phosphatidylinositol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026825">
        <property type="entry name" value="Vac14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021841">
        <property type="entry name" value="VAC14_Fig4p-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16023:SF0">
        <property type="entry name" value="PROTEIN VAC14 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16023">
        <property type="entry name" value="TAX1 BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12755">
        <property type="entry name" value="Vac14_Fab1_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11916">
        <property type="entry name" value="Vac14_Fig4_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="HEAT" evidence="5">
        <location>
            <begin position="86"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar protein 14 C-terminal Fig4-binding" evidence="7">
        <location>
            <begin position="580"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="279"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="418"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="837"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="279"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="306"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="441"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="459"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="837"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="852"/>
            <end position="865"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF11916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ30507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="891" mass="99423" checksum="ADD1AABD9F7714AE" modified="2011-01-11" version="1">MDVSIQRALNDKLYDKRKVGALELERVIRELVVTKDYPRVQAILEQLCNEFAYAVHQPHARNGGLIGLAAAAIALGHELPRYLEKIVPPVLACFTDQDARVRYYACEAMYNIAKVAKGEILIYFNDIFDALCKLGADSELSVKNGAELLDRLIKDIVSESAASYVSVLEGELGQDIPDKDELQDRPPPPTAFSLRRFIPLLQERIWVINPFTRQFLVGWITLLDSIPDLELVTFLPDFLAGLLRFLSDPNRDVHVATRACLDKFLSEIKRISRIKKGIAESKKSREGGKRKREESVDSDSVQIGPEEGDEIDSQTDDSESSGEEDWIPGQDVQINYRKILEILTATLDSPLEEDSLLESLRWIVEFLDICPEEVLPFTPKVLAHMLPAMASGVESIRQAAARVNAGLMDYVVSLSDEPEIGGHSHSTSRIPVSGEKQEGPSSARASLSSSRDLELRSPTPAQGHNRSLSTPNPPYASNHPQVDLDYAAAVNALTLLFLNDHEATRVAALTWLIMLHRKAPRKVLAFNDGTFPALLKTLSDPAEAVVTKDLQLLSQISRNSEDDYFSNFMVNLLQLFATDRKLLETRGNLIIRQLCVSLSAERIYRTLADCIEKEEDVEFASIMVQNLNNNLITAPELSELRKRLRNLESKDGQTFFVALFRSWCHNAVATFSLCLLAQAYEQAYNLLQIFAELEMTVNILIQIDKLVQLIESPVFTYLRLQLLEPEKFPHLYKCLYGLLMLLPQSSAFAALKNRLNAVSSIGYLHIAPKVSPPSATSSTYDRPNRLKSREDSIIRWNELLEKFRTVQERARRAQRHSGDLDDGRSSLGVADLRLGEGLDIKGPKEARNSSGPPVPTKDPPPPVAPPAAKRSGLGMRQIRNLGGAVRGKRPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QI48</accession>
    <name>E3QI48_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">aldehyde dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="4">1.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_05807</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>an aldehyde + NAD(+) + H2O = a carboxylate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:16185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="4"/>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094683.1">
        <property type="nucleotide sequence ID" value="XM_008096492.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QI48"/>
    <dbReference type="STRING" id="645133.E3QI48"/>
    <dbReference type="GeneID" id="24411172"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05807"/>
    <dbReference type="eggNOG" id="KOG2450">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_1_0_1"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07102">
        <property type="entry name" value="ALDH_EDX86601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000009">
        <property type="entry name" value="Aldehyde dehydrogenase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000012">
        <property type="entry name" value="NAD-dependent succinate-semialdehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="9">
        <location>
            <begin position="6"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="329"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ30663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="467" mass="51081" checksum="984F4D75F6007B03" modified="2011-01-11" version="1">MSVEVLKTISPTTNEPVITRNGVSQTDLDELPTTATKAFESWSKTSLADRQSIVKKALKLLLEKKDELAEELTVQMGRPIAYTGGEVATAVKRGEYLLKISEEVLKDTGGEPEKGFKRFIRKVPVGPVLVLFAWNYPYLILVNSLIPALLAGNTVILKPSPQTPTIVERVAEVFEEAGLPTGVLQYFHCGSPIMIESIVRNPKVKLVAFTGSVAGGLAVQQAASDRIVNVGLELGGKDPAYIRDDVDIKWAAEEIVDGAVFNSGQSCCSVERVYVADKIHDAFVTAVQKVLEGYKLGDPFDKGTHVGPVISKRSKEMIESHIKDAIAKGATDATPANETFDNPPPKGNFVKPTLLTGVNHSMTVMTEETFGPVIPVQRVKSDEEAVQLMNDSEFGLTASIWTKDTERGYELADQVEAGTVFVNRCDYPSPDLAWTGWKNSGKGQTLSRFGYDQFVKLKSYHLKDYPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QI79</accession>
    <name>E3QI79_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Ferrochelatase</fullName>
            <ecNumber evidence="12">4.98.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_05838</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the ferrous insertion into protoporphyrin IX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>heme b + 2 H(+) = protoporphyrin IX + Fe(2+)</text>
            <dbReference type="Rhea" id="RHEA:22584"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="EC" id="4.98.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Porphyrin-containing compound metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the ferrochelatase family.</text>
    </comment>
    <dbReference type="EC" id="4.98.1.1" evidence="12"/>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094714.1">
        <property type="nucleotide sequence ID" value="XM_008096523.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QI79"/>
    <dbReference type="STRING" id="645133.E3QI79"/>
    <dbReference type="GeneID" id="24411203"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05838"/>
    <dbReference type="eggNOG" id="KOG1321">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018884_1_0_1"/>
    <dbReference type="OrthoDB" id="1323at2759"/>
    <dbReference type="UniPathway" id="UPA00252">
        <property type="reaction ID" value="UER00325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004325">
        <property type="term" value="F:ferrochelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006783">
        <property type="term" value="P:heme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00419">
        <property type="entry name" value="Ferrochelatase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03411">
        <property type="entry name" value="Ferrochelatase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1400:FF:000003">
        <property type="entry name" value="Ferrochelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1400">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00323">
        <property type="entry name" value="Ferrochelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001015">
        <property type="entry name" value="Ferrochelatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019772">
        <property type="entry name" value="Ferrochelatase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033644">
        <property type="entry name" value="Ferrochelatase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033659">
        <property type="entry name" value="Ferrochelatase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00109">
        <property type="entry name" value="hemH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11108">
        <property type="entry name" value="FERROCHELATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11108:SF1">
        <property type="entry name" value="FERROCHELATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00762">
        <property type="entry name" value="Ferrochelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53800">
        <property type="entry name" value="Chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00534">
        <property type="entry name" value="FERROCHELATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="6 12" id="KW-0408">Iron</keyword>
    <keyword evidence="10 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 12" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11 12" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ30694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="433" mass="47799" checksum="FBAAA76B743062F2" modified="2011-01-11" version="1">MAFKYPTGRLSRSLSKATPLTRHASSPFALASPQSRLLATVPPVTQNSVGSKGPTAMVFMNMGGPSTTGEVGDFLSRLFADGDLIPLGRFQNYLGPFISKRRTPKIEKQYAEIGGGSPIRKWTEYQNAEMCQILDEISPETAPHKPYTAFRYADPLTEEMYNQLLADGFGNGKGGRAVAFTQYPQYSCSTTGSSLNELWKWRQRLEGKAVGETTPGDGTISWSVIDRWPVHPGLIEAFAQNIEAKLLEYPEERRKDVVLLFSAHSLPMSVVNRGDPYPAEVAATVYAVMQRLKFSNRYRLCWQSQVGPSAWLGPQTSDSVEHYVQKGQKDLVLIPIAFTSDHIETLYELDLEVIGDSGSPETVKRVESLNGSPIFIKALADIAKAHLDSGVACSQQMELRCPGCTSERCLQSKKFFAGQQTKLSSAQERILSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIN9</accession>
    <name>E3QIN9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_05793</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094669.1">
        <property type="nucleotide sequence ID" value="XM_008096478.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIN9"/>
    <dbReference type="STRING" id="645133.E3QIN9"/>
    <dbReference type="GeneID" id="24411158"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05793"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_8_4_1"/>
    <dbReference type="OrthoDB" id="440553at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1720.10:FF:000009">
        <property type="entry name" value="MFS multidrug transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF51">
        <property type="entry name" value="QUINIDINE RESISTANCE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="153"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="176"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="236"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="338"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="374"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="427"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="457"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="493"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="517"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="87"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="296"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="296"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ30649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="555" mass="59976" checksum="7B5404AC066DDD11" modified="2011-01-11" version="1">MGEDELNEKVPGEDQHRPDLSTTSPEPSVRPVSSISEPEVINDDDQHDATSGDRPDPASERFDPENLTRQPSGPAYSVIALSTKRGITLMATVACFISPMSANIYYPVLAPIADDLGVSIALVNLTVTSYMILQAISPTIFGDFGDMAGRRPAFLVAFSIYLVACVGLALQRNYAALLVLRMLQSAGSSGAIALGFAMVADISMSSERGKYMGIVGAGINVGPTIGPVLGGVLTQYFGWASIFWFCVVLVGLWIVPYALFIPETCRNVVGNGSLPAQPWNRPVVDLIRRRRRRNAADANALSRSASTATAAQPKGKLQFPNPIRSVKIIFEREMGLMLAYNSLLYVAFICVTATLGTLFREIYGFNDLELGLCYLPYGAGCVVASVGQGYVLDWNYRRLARKIGFTIDRRRGDDLSKFPIEKARLQPVYPAVAIGLVALVAYGWVLQIETSVAVPLVLQGVIGLTITGSFNIMNTLIVDLFPDAPATATAANNLVRCAMGAVGTAVIDYMISGMGRGWSFTFLAALCAVLSPMMFLIAKKGPRWRNERRTRSDAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIR1</accession>
    <name>E3QIR1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 12">Cysteine dioxygenase</fullName>
            <ecNumber evidence="3 12">1.13.11.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_05893</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>L-cysteine + O2 = 3-sulfino-L-alanine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20441"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:61085"/>
            <dbReference type="EC" id="1.13.11.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="12">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the cysteine dioxygenase family.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.20" evidence="3 12"/>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094769.1">
        <property type="nucleotide sequence ID" value="XM_008096578.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIR1"/>
    <dbReference type="STRING" id="645133.E3QIR1"/>
    <dbReference type="GeneID" id="24411258"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05893"/>
    <dbReference type="eggNOG" id="KOG4064">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079443_4_0_1"/>
    <dbReference type="OrthoDB" id="543511at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017172">
        <property type="term" value="F:cysteine dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019448">
        <property type="term" value="P:L-cysteine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10548">
        <property type="entry name" value="cupin_CDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000189">
        <property type="entry name" value="Cysteine dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010300">
        <property type="entry name" value="CDO_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12918">
        <property type="entry name" value="CYSTEINE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12918:SF1">
        <property type="entry name" value="CYSTEINE DIOXYGENASE TYPE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05995">
        <property type="entry name" value="CDO_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12 13" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="8 11 12" id="KW-0408">Iron</keyword>
    <keyword evidence="4 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0883">Thioether bond</keyword>
    <feature type="binding site" evidence="11">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="cross-link" description="3'-(S-cysteinyl)-tyrosine (Cys-Tyr)" evidence="10">
        <location>
            <begin position="112"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00070673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR610300-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR610300-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU366010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ30749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="215" mass="23949" checksum="BD979136DB5F07C3" modified="2011-01-11" version="1">MALDILTKITSAFGRDLKHDGNRFDELVWGLKEALGPSSGLDSADVDVKELMKLMEEYNTRESEWVQFAFAEKGMGYTRNLVDEGNGKSNLLVLVWTPGKGSPIHDHGNAHCLMKILKGDLTEIRYAFPEGDAEQPMKVISERTHKENAVAYMADELGVHRVCNRGSDFAVSLHLYTPPNVAKGGCNIFNEKTGKRSHVAKCGYYSAYGRRLPKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJE5</accession>
    <name>E3QJE5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_06127</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ30983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095003.1">
        <property type="nucleotide sequence ID" value="XM_008096812.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJE5"/>
    <dbReference type="GeneID" id="24411492"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06127"/>
    <dbReference type="eggNOG" id="KOG3098">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2236401_0_0_1"/>
    <dbReference type="OrthoDB" id="196103at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="105" mass="12118" checksum="8BC5FD8B4E50E519" modified="2011-01-11" version="1">MAVATLCNRRVVCMLPLFFCASVFYPYQQNSINGMKFNIRTRSLNGALYWIAHMFGGLLISLLLDLSMLERPGPSRFGWVLLFVTDMASWDGGYQFKQWQDSWHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QK86</accession>
    <name>E3QK86_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_06418</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697354">
        <property type="protein sequence ID" value="EFQ31274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095294.1">
        <property type="nucleotide sequence ID" value="XM_008097103.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QK86"/>
    <dbReference type="STRING" id="645133.E3QK86"/>
    <dbReference type="GeneID" id="24411783"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06418"/>
    <dbReference type="eggNOG" id="ENOG502SJ4R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039411_0_0_1"/>
    <dbReference type="OrthoDB" id="3922785at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="503"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="515"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="524" mass="57331" checksum="B889E68046EA885A" modified="2011-01-11" version="1">MSKADHAATAYRDDIIGGYPVPLTAAALRAAAKSKRNNSNDSSGICVENEYRQPASPSVRADAAIGPRLNIRHNQQRPGLSIRRFGRSDFERFNEEAANPAGIVYIDISFKQPPEHMLSNANVLITLSEDAPPAHGRFGRRRPIRTSLDSEHAVQVTEYFGPHAIHGPQGKSLATNERAFQPTIGAGGMVEIGGMGTRQSVTRQYIDSWTFKGTQKRAKDGIGLRCLEWELTENDTEKKPSVDMCVEIEGRLKSKAKQGNQRLLRSRSRSSDKDNVMVTRIDLSTAINDFQHKLDQLAFGLNIDMQRTNLEAIPVEMLVPTQATFKPVAWNAIPYADEAILNSLLEAPDEGTNELKEFLLQETTQPPASKISQPVYSGNSSSGDGTLVNYSGRTISGGSTAPKHIAWRVPEVMILALVRWLMLTLKAVGAEDVYLAGILVSTDDGVKTTADRDITIDRVESEIRSRSGSRMESVPNGRLLDAAATQSVSAGLLVPEPYGSRFQSRQRRLGHGRVSGQNGASMEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKD3</accession>
    <name>E3QKD3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycoside hydrolase 131 catalytic N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_06465</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697354">
        <property type="protein sequence ID" value="EFQ31321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095341.1">
        <property type="nucleotide sequence ID" value="XM_008097150.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKD3"/>
    <dbReference type="STRING" id="645133.E3QKD3"/>
    <dbReference type="GeneID" id="24411830"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06465"/>
    <dbReference type="eggNOG" id="ENOG502SHCH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063723_0_0_1"/>
    <dbReference type="OrthoDB" id="5283326at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041524">
        <property type="entry name" value="GH131_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34612">
        <property type="entry name" value="GH131_N DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34612:SF4">
        <property type="entry name" value="GLYCOSIDE HYDROLASE 131 CATALYTIC N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18271">
        <property type="entry name" value="GH131_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178574" description="Glycoside hydrolase 131 catalytic N-terminal domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase 131 catalytic N-terminal" evidence="3">
        <location>
            <begin position="32"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ31321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="303" mass="32362" checksum="DCCFCECEE1D4E4A1" modified="2011-01-11" version="1">MFSRAALLLLLTPATLAAATPNCHAAAVRCPIVFDGRVPAVATPQDFDTASGGGWNPYNPGYVKGEGLLWSDIILLPLPSPQEEEEEAAPPSRFDAGGGTRPLEVTVSDRSIFMNQRGFRRAGLQFAADANVGSPAAAGVKTLHFSVRQDAARPLNLTHEYLNVWHETAAYDANQFNFQTGTLIGREGLLPKDTFKLLDRDNKLLWSTPVATDGSWQNFALTLDFSKNTIQVWYSTGGARLASQGGAIPANLAGDGQYQIGILKKPTGTSDVVNSGYQSSNLDEGQIYGGIFIEDGADGCVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKS5</accession>
    <name>E3QKS5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Capsule polysaccharide biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_06607</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697355">
        <property type="protein sequence ID" value="EFQ31463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095483.1">
        <property type="nucleotide sequence ID" value="XM_008097292.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKS5"/>
    <dbReference type="GeneID" id="24411972"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06607"/>
    <dbReference type="eggNOG" id="KOG4366">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1547434_0_0_1"/>
    <dbReference type="OrthoDB" id="265761at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051490">
        <property type="entry name" value="THEM6_lcsJ_thioesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12475">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12475:SF4">
        <property type="entry name" value="PROTEIN THEM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="173" mass="19802" checksum="425F873D1DAF23EF" modified="2011-01-11" version="1">MASAIAKATRTEADLDRVPVRVVRFVRLATAGGLAYAAYRIHWRVLLANFFTGPGRISRILMLFFALLNLKNMPFVWTYRVWSAIIYHLFIRKSPRLGPRSLFRPMISQSHAPITEIDYNIHKSNSTYFADLDVSRTHLCTYLLRPGFRRLAHNATTGLDARLANLLKELQLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLD8</accession>
    <name>E3QLD8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">AP-2 complex subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_06965</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <location evidence="1">Coated pit</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the adaptor complexes large subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697356">
        <property type="protein sequence ID" value="EFQ31676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095696.1">
        <property type="nucleotide sequence ID" value="XM_008097505.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLD8"/>
    <dbReference type="STRING" id="645133.E3QLD8"/>
    <dbReference type="GeneID" id="24412330"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06965"/>
    <dbReference type="eggNOG" id="KOG1077">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003824_1_0_1"/>
    <dbReference type="OrthoDB" id="28053at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030122">
        <property type="term" value="C:AP-2 adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035615">
        <property type="term" value="F:clathrin adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072583">
        <property type="term" value="P:clathrin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000020">
        <property type="entry name" value="AP-2 complex subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="entry name" value="TATA-Binding Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050840">
        <property type="entry name" value="Adaptor_Complx_Large_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017104">
        <property type="entry name" value="AP2_complex_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003164">
        <property type="entry name" value="Clathrin_a-adaptin_app_sub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008152">
        <property type="entry name" value="Clathrin_a/b/g-adaptin_app_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013041">
        <property type="entry name" value="Clathrin_app_Ig-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009028">
        <property type="entry name" value="Coatomer/calthrin_app_sub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22780">
        <property type="entry name" value="ADAPTIN, ALPHA/GAMMA/EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02296">
        <property type="entry name" value="Alpha_adaptin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02883">
        <property type="entry name" value="Alpha_adaptinC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037091">
        <property type="entry name" value="AP2_complex_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00809">
        <property type="entry name" value="Alpha_adaptinC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49348">
        <property type="entry name" value="Clathrin adaptor appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55711">
        <property type="entry name" value="Subdomain of clathrin and coatomer appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0168">Coated pit</keyword>
    <keyword evidence="3 7" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin adaptor alpha/beta/gamma-adaptin appendage Ig-like subdomain" evidence="10">
        <location>
            <begin position="715"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="653"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="657"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="20"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate)</name>
            <dbReference type="ChEBI" id="CHEBI:57836"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate)</name>
            <dbReference type="ChEBI" id="CHEBI:57836"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate)</name>
            <dbReference type="ChEBI" id="CHEBI:57836"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="65"/>
            <end position="69"/>
        </location>
        <ligand>
            <name>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate)</name>
            <dbReference type="ChEBI" id="CHEBI:57836"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR037091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR037091-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ31676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="980" mass="109824" checksum="060E5172FADA8984" modified="2011-01-11" version="1">MSSAASGFLGRSTSNNSNMRGLVQFIADLRNARARELEEKRINKELANIRQKFKDGNLSGYHKKKYVCKLLYIYILGWNVDFGHLEAVNLISANKYSEKQIGYLAMTLFLHEKHELLHLVVNSIRKDLLDHNELFNCLALHAIANVGGREMGEALSGEVHRLLISPTSKAFVKKKASLTLLRLYRKNPDIVQPQWAERIISLMDDVDVGVALSVTSLVMALAQDNLDAYKGAYAKAAARMKRIVIDGEYTPDYLYYKVPCPWLQVKLLRLLQYFPPSDDTHIRDMIRESLQKILNLAMEQTKNVQQNNAQNAVLFEAINLIIHLDNENALLKQISSRLGRFLTSRETNVRYLGLEAMTHLAARIDTLEPIKQHQDVILGSLKDRDISVRRKGLDLLYSMCDSSNAQVIVGELLHYLQNADFAIREEMVLKIAILTERYATDVQWYVDISLRLIAMAGDHVSDEVWQRVIQIVTNNEELQVYASQHSLQYVKSDHCHETLVKIGAYILGEFGHLIADQPKCSPIEQFLALQSKIAACSSSTRAMILSCYVKFVNLFPEIKPQLLKAFQVFSHTLDSELQQRACEYLTLATMPTDDLLRTVCDEMPPFSERQSALLARVHQKHANTSDKRTWIVGGKDANTDAVELKIAKEGGLKRTFSTNGNPNASNGGPNGTNGNGVNDLAGLDMNNIGPAEPKTKAPNLASAAHLSPNWEIGYNKLLLKAEGILYEDGQIQVGVRSEYRGQMACLILYFKNKTPTALSSFTTTLDLDENEKGKLTWDVKNLPESTIYQGGQSQQVVMFECKSVFDKSPTVRISYLAGALQAVTLKLPITAHKFMDPADLSAEDFFRRWKQIGGAPREAQQIFGLTPGKADRELTEFFVRQTVEGFRWRVLDGVDPNAKNFVGASVLHTSEAGKFGCLMRLEPNYGTKMVRLTIRATDDSVPAVLLKIMQERLAAGYTPEKFQAPTPADISDAFSNVMVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLP2</accession>
    <name>E3QLP2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">LipA and NB-ARC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_06755</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the putative lipase ROG1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697357">
        <property type="protein sequence ID" value="EFQ31780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008097609.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLP2"/>
    <dbReference type="STRING" id="645133.E3QLP2"/>
    <dbReference type="GeneID" id="24412120"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06755"/>
    <dbReference type="eggNOG" id="KOG2029">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001668_0_0_1"/>
    <dbReference type="OrthoDB" id="5086500at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007751">
        <property type="entry name" value="DUF676_lipase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48187">
        <property type="entry name" value="LD21810P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48187:SF2">
        <property type="entry name" value="LD21810P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05057">
        <property type="entry name" value="DUF676"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF676" evidence="3">
        <location>
            <begin position="76"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="823"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="929"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="939"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="969"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="992"/>
            <end position="1001"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ31780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1001" mass="113371" checksum="DA0BA7BD47D6D6DB" modified="2011-01-11" version="1">MPPNLVVALAKLLQEYGYWLHSYIEKKPRRVRFMLSACKVNSAPHFALSHDGSINKHISRYEITAVFTHPDAVVDVVLVHGLNGDPEKTWTSSDAKRVFWPAELLPQSLGKTRANILVYGYNADVYTTGKSSKSASDNFISQHAQTLVTNLTLYRKSERTSNNPIIFVAHSLGGLLVKRALLYSNDVRDKNQEDARSIFVSTYGIIFLGTPHTGSDMATWGLVLQKMADAIAPRKVFESESVLLKTLKKDNETLENINNHFLDVYQRFQIHMAHENHKTDVKGTKMLVVDAKSASPQLPGVTYYGIEATHSGMCKFNSTSAPGYRNVSTAIRDWAEEAPPVIRTRWEIEIDDRRARAQSEAVERMHLSNALSTQVSSPTAIADTMGFSPFASVRESYTPRPIFVHPDRFRPNSFFKGRQDELRSLHKVLTDAKRRSEGTSAVLIQGIPGAGKTHLARQYVFNHKDDYPGGIYWIRSTSLQDMEDGFWHIAKTEAIRGMAAQEEKKDLLNPQKMVEIVRNWFNESENWLLVFDGIRFGDNAVLDFIPDRPNSSLIYTSTERAEAGAYRLDNPSIMKLGLLPVQDAQELLLEEMGKKQPYTTDDLRRAQDLVQLMGRLPLMIHAAALQMNVTREPLAKYLKSFRDIPRVGILPAYKTIRDQLQKRGDVAALNLIYILSFFSQSMPVEMLALGLKALDKRTPVKTETTRHKKSLTQTLVTLINFALIERNETDDIPSSSSQSTRQSVELIPEPLDTLRVHSIVQAFFMELLAEERQLEFWLERAVRVFCQSLDEADARMGTDPDTGLPDDYRQYVRHGKKLMEHLDRHGHSHKHHKAKEQPNSQRDNPADLVTAKADLERRLAKLPREIDKLQKAVSTDIVDGNKTATHSSVFERTCSISSQSTEASNGTNLPNRTYSEDVECESPLPFVDPNHFHMPYRSFPEDNEPRAEDERSEDRTITPYPPDVVEGPNPNSSESEWTVVSKHRSYQSGVRPRSHHSTSVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLY3</accession>
    <name>E3QLY3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="3 6">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_07015</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="3 6"/>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095891.1">
        <property type="nucleotide sequence ID" value="XM_008097700.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLY3"/>
    <dbReference type="STRING" id="645133.E3QLY3"/>
    <dbReference type="GeneID" id="24412380"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07015"/>
    <dbReference type="eggNOG" id="KOG0549">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013615_8_1_1"/>
    <dbReference type="OrthoDB" id="1902587at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.40:FF:000006">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044609">
        <property type="entry name" value="FKBP2/11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45779">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45779:SF7">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0697">Rotamase</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178613" description="peptidylprolyl isomerase" evidence="7">
        <location>
            <begin position="22"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="8">
        <location>
            <begin position="41"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ31871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="182" mass="19384" checksum="BAAFD03601EBDC32" modified="2011-01-11" version="1">MQGLLLSLGLLASSAVSFVAAADLRIDVTQEVECDRKTKNGDKLTMHYRGTLQADGSQFDASYDRGTPFTFKIGSGQVIKGWEQGLLDMCIGEKRTLTIPPELGYGSRGMGPIPASSTLVFETELVGIEGVPKPEKIVIKEKASQAAEGVAEKVASKVAEAAEVVKTIVADTDSDAQEHNEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMG4</accession>
    <name>E3QMG4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">GLRG_07196</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10 17">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096072.1">
        <property type="nucleotide sequence ID" value="XM_008097881.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMG4"/>
    <dbReference type="STRING" id="645133.E3QMG4"/>
    <dbReference type="GeneID" id="24412561"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07196"/>
    <dbReference type="eggNOG" id="KOG0922">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001832_2_3_1"/>
    <dbReference type="OrthoDB" id="10253254at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005684">
        <property type="term" value="C:U2-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000390">
        <property type="term" value="P:spliceosomal complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05684">
        <property type="entry name" value="S1_DHX8_helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000061">
        <property type="entry name" value="ATP-dependent RNA helicase DHX8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1080:FF:000001">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000101">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000191">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049945">
        <property type="entry name" value="AAA_22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049621">
        <property type="entry name" value="S1_DHX8_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF85">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13401">
        <property type="entry name" value="AAA_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="12">
        <location>
            <begin position="230"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="543"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="724"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="76"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="143"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="319"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="436"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="92"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="446"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EFQ32052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1198" mass="134623" checksum="180847DB7F4BBC69" modified="2011-01-11" version="1">MDDLLNLELLSLVSKVTSELQNHLGVSDKTLAEFIIAQRVDADDYDGFQKKLAAMGADFPPSLVDSVDRLVLTMHPKMKGKAQKTGGDNGSNEDRHHRSAAEKEQIFRGLAVPDKPVAYDNIGDGIDAIDDTLALLEGLEGKARRDNRDTRKRSRSPDDGRESRRKRRGRSKSRERNKRDKYRSRSRSHDDYENGPSLKQKSRRRNYDDEDDGRFRRAPEPEVDDAPQLHKIYGGHVTGIKDFGAFVNIHGVRGKVDGLVHISRLVDGQRVNHPSDLLTKGQEVWVKVVSMEGNRIGLSMKEVDQETGLDLHPEVRISSGANMEELGGRGRNGNMFDESPMPPPQHQPRRQKKRMTSPERWEIRQLIASGVAKASDYPDLEEDYNATLRGDGELELEQEVDIEVREEEPPFLAGQTKQSLELSPIRVVKAPDGSMNRAAMSGTSLAKERKELKQQEAEAAAADDSKVDLSAQWNDPMADPDKRKFASDMRNARSQMAQNKPDAVPEWKRAVAPKDQAFGRRTNMSIKEQRESLPVYAFRQKFLDAVREHQVMVVIGETGSGKTTQLTQYLAEDGFANDGVIGCTQPRRVAAMSVAKRVAEEVGTPLGEAVGYTIRFEDKTSPATKIKYMTDGMLQREILVDPDLRRYSVIMLDEAHERTISTDVLFALLKKTMKRRKDLKVIATSATLDADKFSSYFDGCPIFTIPGRTFPVEILYSREPESDYLDAALVTVMQIHLTEPPGDILLFLTGQEEIDTSCEILYERMKALGPNVPELIILPVYSALPNEMQSRIFDPAPPGCRKVVIATNIAETSITIDNIYFVVDPGFVKQNAYDPKLGMDSLVVTPISQAQANQRAGRAGRTGPGKCFRLYTEAAYQSEMLPTTIPEIQRQNLSHVILMLKAMGINDLLHFDFMDPPPINTMLTALEELYALSALDDEGLLTRLGRKMADFPMEPSLAKVLIISVDMKCSAEMLIIVAMLNLPNVFYRPKEKQSQADQKKAKFHDPHGDHLTLLNVYNSWKQSSYSSPWCFENFIQARSMKRAKDVHDQLVKIMERYRHPIVSCGRHTQIVRQALCSGFFRNAARKDPQEGYKTLIEGTPVYLHPSSALFGKQAEWVIYHTLVLTTKEYMHCTTSIEPKWLVDAAPTFFKVAPTDRLSKRKKAERIQPLHNKYAGEDDWRLSAQRKGGRGGGGGGTWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMQ9</accession>
    <name>E3QMQ9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Vesicle tethering protein Uso1/P115-like head domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_07291</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697360">
        <property type="protein sequence ID" value="EFQ32147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096167.1">
        <property type="nucleotide sequence ID" value="XM_008097976.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMQ9"/>
    <dbReference type="STRING" id="645133.E3QMQ9"/>
    <dbReference type="GeneID" id="24412656"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07291"/>
    <dbReference type="eggNOG" id="KOG0946">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006318_4_0_1"/>
    <dbReference type="OrthoDB" id="198977at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005795">
        <property type="term" value="C:Golgi stack"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048211">
        <property type="term" value="P:Golgi vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048280">
        <property type="term" value="P:vesicle fusion with Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000296">
        <property type="entry name" value="Related to transport protein USO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006955">
        <property type="entry name" value="Uso1_p115_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024095">
        <property type="entry name" value="Vesicle_P115"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006953">
        <property type="entry name" value="Vesicle_Uso1_P115_head"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10013">
        <property type="entry name" value="GENERAL VESICULAR TRANSPORT FACTOR P115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10013:SF0">
        <property type="entry name" value="GENERAL VESICULAR TRANSPORT FACTOR P115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04871">
        <property type="entry name" value="Uso1_p115_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04869">
        <property type="entry name" value="Uso1_p115_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vesicle tethering protein Uso1/P115-like head" evidence="5">
        <location>
            <begin position="339"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="domain" description="Uso1/p115-like vesicle tethering protein C-terminal" evidence="6">
        <location>
            <begin position="862"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="803"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="950"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="803"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="815"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="958"/>
            <end position="974"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ32147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="974" mass="108715" checksum="E2AA852D305512BB" modified="2011-01-11" version="1">MFSISTAPAKQSVGETITVLSGRLSSATLLEDRRAAILGLRSFAKDFPASVASGALRSLIGSLSNDAEDVDTVKVVLETLLMLFSPNEDSPEASEEIALWLADEFTQRQENITLLLNFLDSADFYSRLYSLQLLAAILSARTERTEECVFTAPLGISRLVAVLDDSREAVRNEAINLLIFLTPSSTDIQKLVAFENAFDRLFNIISLEGSLSEGDRVVEDCLILVANLLRRNPSNQSLFRESGGIRRLANLLEGAEKAQREDVEVAAWAQTQRNRNIYALLAVVRLFLVAGAVGTSQNQLAFWQHGLLYNALQLAFSHVAQLPIKAEALVTCADIIRGNPSLQEGFAQLQVSSPLEPPTPNEAGQPKGVVKVYVIDGLLDLTLSVQDSEAFDLRLAACDCLKAYFHSHTDIRLHFLRRAIEGHNTGADETANVLTVLLRPSSDAAVANPYRSWFAATIMLHLVFDNPEAKSMAMAVTEGDAKNGEEVVTSIQTIAAHLISGLNREQDSRVVVGYLMLLLGWLFEDLDAVNDFLGEGTNTQSLIQAVNHPYPSGDVVQGLCAMLLGVLYEFSTKDSPISRADLHSILVSRMGRERYIDKLTKLRSDPLVRDFEVIPQKLGNSGSGKLPDVYFDATFVDFFKDNYSRIIRGIDRDPGLEISVVSNGIQKGVSRELVDSLRAQLTEKDHALQEAQVNLETISRQLGQEQADHRRTRETTAMELARIKQMNEGIQKQHDAELRNLQSRIASLQEEHQRQDDLARRRTESQIATLEQQHKRQLDDVQRNAAFRITFLEQELKKQADQAEQTAKVQAASQQEEHRKQLEQARKTAESDADRVRHRAEADMADLKATISRLEVDLMKAKKSKAQELQSVREELEKRLQEQESFVTKSEARVEQLEKDLREIREKAVHGEVAVKKAEEDKKTTQNELDDLLMVFGDLEEKVAKYKAKLEELGETVSDGEDDEDDEEEDGDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPC4</accession>
    <name>E3QPC4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">2-isopropylmalate synthase</fullName>
            <ecNumber evidence="7">2.3.3.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">GLRG_07856</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3-methyl-2-oxobutanoate + acetyl-CoA + H2O = (2S)-2-isopropylmalate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21524"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.13" evidence="7"/>
    <dbReference type="EMBL" id="GG697364">
        <property type="protein sequence ID" value="EFQ32712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096732.1">
        <property type="nucleotide sequence ID" value="XM_008098541.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPC4"/>
    <dbReference type="STRING" id="645133.E3QPC4"/>
    <dbReference type="GeneID" id="24413221"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07856"/>
    <dbReference type="eggNOG" id="KOG2367">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004588_3_0_1"/>
    <dbReference type="OrthoDB" id="418791at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003852">
        <property type="term" value="F:2-isopropylmalate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:L-leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07942">
        <property type="entry name" value="DRE_TIM_LeuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000045">
        <property type="entry name" value="2-isopropylmalate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.270:FF:000002">
        <property type="entry name" value="2-isopropylmalate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00572">
        <property type="entry name" value="LeuA_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013709">
        <property type="entry name" value="2-isopropylmalate_synth_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002034">
        <property type="entry name" value="AIPM/Hcit_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005668">
        <property type="entry name" value="IPM_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054692">
        <property type="entry name" value="LeuA-like_post-cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036230">
        <property type="entry name" value="LeuA_allosteric_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039371">
        <property type="entry name" value="LeuA_N_DRE-TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00970">
        <property type="entry name" value="leuA_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002991">
        <property type="entry name" value="PRK03739.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46911">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46911:SF1">
        <property type="entry name" value="2-ISOPROPYLMALATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22615">
        <property type="entry name" value="IPMS_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08502">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00917">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110921">
        <property type="entry name" value="2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89000">
        <property type="entry name" value="post-HMGL domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00816">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="15">
        <location>
            <begin position="33"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="621"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="621"/>
            <end position="631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EFQ32712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="651" mass="72148" checksum="9A725D1E48EA0930" modified="2011-01-11" version="1">MPMLKEPWKKYKPFPPLNLPDRQWPSKTITKAPRWLSTDLRDGNQSLVDPMARLLPPHGLPPTVLSRVQNGDEKWRYFKMLCDLGYKEIEVSFPSASQTDFDFTRRLIETPGAVPDDVYLQVLSPCREDLIKRTVESLKGAKNAIVHIYLATSECFRRIVFGFTEDESVELAVKCAKLVRSLTKDDPSQSGTNWQFEFSPETFSDTSPEFVIRICEAVKAAWEPTTEVPIIFNLPATVEMATPNVYADQIEYFCRNITEREKIAVSLHPHNDRGCAVAAAELAQMAGADRVEGCLFGNGERTGNVDLVTLGLNLYTQGVYPNVDFSDLNRVIDMVEVCNKIPVHPRAPYGGSLVVCAFSGSHQDAIKKGFQVREQTVKSNDEHWQLPYLPLDPTDIGRTYEAIIRVNSQSGKGGAAWIILRKLQLDLPRGLQVAFSKVVQDKADQLGRELLSDEITELFESTYYLRDNPRFTLVDYSIAPDRSRSPAPPQPGKTQDTKNLQRVFEGVVAIDGKEYRLRGHGNGPISSLANALKSVGVTLDVEDYKEHAIGAGRDVKAATYIECTATGTKQRYWGIGIHEDVVQSSLIALLSAASNFIGSRPGSPVFHKPVPTRPMSQELNLESANGTNGTNGAPHEAPGLVSVLEDKANGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPL2</accession>
    <name>E3QPL2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycosyl hydrolase family 43 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_07933</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697365">
        <property type="protein sequence ID" value="EFQ32789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096809.1">
        <property type="nucleotide sequence ID" value="XM_008098618.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPL2"/>
    <dbReference type="STRING" id="645133.E3QPL2"/>
    <dbReference type="GeneID" id="24413298"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07933"/>
    <dbReference type="eggNOG" id="ENOG502QSGV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016116_1_1_1"/>
    <dbReference type="OrthoDB" id="3426327at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18821">
        <property type="entry name" value="GH43_Pc3Gal43A-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22925">
        <property type="entry name" value="GLYCOSYL HYDROLASE 43 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22925:SF39">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_5G14190)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180679" evidence="5">
        <location>
            <begin position="20"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ32789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="502" mass="55796" checksum="927AAEBE9CAD46BD" modified="2011-01-11" version="1">MPFAKLFSSGLLFASLAASRWIVPGGRWHDTEGNLVNAHAGGITLDKDTGKFFWFGEYKVEGQEEGGGVSVYSSDDLATWEYRGKALEPVQGHPYISNDMIIQRPKVVFSEPTGEYHMWWHADNSTYGLLLQGLATSPNISGPYTFVDAIAPLGNWSQDFGIFTDYKDGRSYALYSNGDRVEGRDVYVTSFNDDLTNVTEVVHRFDKYDLEAPTIIQTDKSYYALMSHKTGYRPNNVVAFRADSLAGPWSQPFMVADPYSRTYSSQSGFSLKIDGSETTTYLYLGDQWDSNSLWESRYIWLPIAVDDEKKSLHVEWHDVYDLDIGTGVVTPIKGTTYYAHEPAVATVAGGASRQEANFASGGFIVTGIYGNDSTVTFYGIQGAGEPQWVSFYYQNTDDMGFGDQPGGTPDRIGGKWQLRRIASVIVNDNEEHVETLFQRDTHKGIILSTPLQLTLDESANNTITIGGLWNGFDFKGADIDRIVVYPPEGGAHRVQEGRLKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQ78</accession>
    <name>E3QQ78_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08160</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697366">
        <property type="protein sequence ID" value="EFQ33016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097036.1">
        <property type="nucleotide sequence ID" value="XM_008098845.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQ78"/>
    <dbReference type="STRING" id="645133.E3QQ78"/>
    <dbReference type="GeneID" id="24413525"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08160"/>
    <dbReference type="eggNOG" id="ENOG502QQSB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031217_0_0_1"/>
    <dbReference type="OrthoDB" id="2099887at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027589">
        <property type="entry name" value="Choice_anch_B"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04312">
        <property type="entry name" value="choice_anch_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38787">
        <property type="entry name" value="REGULATORY P DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38787:SF3">
        <property type="entry name" value="REGULATORY P DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180685" evidence="1">
        <location>
            <begin position="21"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ33016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="582" mass="63418" checksum="C088C4F31FA7B5D4" modified="2011-01-11" version="1">MVRINSAALLGSAMVGLSSAAGAGTKAEYASGEVHHRIMGIKMAQWEAEAEAGLMDSARYPELGYTPCVDGFAAAIPGDANNTFRCGNIDLYHFLSHEALGSWGGRGSSSWGWTSADGREFVAIGQYDGTAFAEISKEGKLVYLGRLPQYDAIGSNWREIRIVGDIVVIGSEAIKHGVQFFDMKKVLDLDPANPKNFTQADLTGHWDELPVGRTHNIVVNQELNYAIACGSVGGNETIRVRDNLPCRGGLIFLDISDPTNVTSPGCAAGDGYVHDAECLVYRGPDARYYGRDICYGYNEDTLTIYDVTDKKGNVTNIISISDFPGAEYIHQGVVNNETWQEYLFLDDEFDERDAKVGPMTQGLPTTHIFDIRDLEKPAYTGHYAGKRRSIDHNQYMFNGYLYQSNYGNGINVLDVSSVTSDPTGAGICEVGFFDVYPEDDEAEGGGVVQFAGSWSSYAKFESGFIFVHTIERGSFVVKMTSKECLKAATDCSADNCLRALRANTIPGRLEESLEFCGNFTARQRTDESLLPEYAAEACVENKDKEPVARVSSACACIPTPVVPELPRTTTRPPVPTVLPPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQD1</accession>
    <name>E3QQD1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_08213</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697367">
        <property type="protein sequence ID" value="EFQ33069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097089.1">
        <property type="nucleotide sequence ID" value="XM_008098898.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQD1"/>
    <dbReference type="STRING" id="645133.E3QQD1"/>
    <dbReference type="GeneID" id="24413578"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08213"/>
    <dbReference type="eggNOG" id="ENOG502STRK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031300_0_0_1"/>
    <dbReference type="OrthoDB" id="4330117at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="9"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="44"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="261"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="309"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="61"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="272"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="319"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ33069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="471" mass="51508" checksum="521FDEBE3929BB6F" modified="2011-01-11" version="1">MSDGPIRKACDRCHRQKLSCKRVGDEACERCIRLKEECTSSPSLRYRKQNQHGSTRDLSRKRVPSPKRQRKKGGHPVAHTDLSIVKTQNLASVCSNTGFPDDGTVPSDAMLDIVDFDFSFGGHSAGLYQSGPNQQQPVQQAFGDSMDALMPDHGDTIAQSWSPVHSTTSDSAFTSPMAPETGFAGRAYLGSPSPYGHLSASSELQEPAPHRISKRCIRQRARQIMLRPYAGGHGSSTEEWMPRITEVNSRLFELSSDLPAQMDSSEEHGRSSMASTPDNGSSTTAPFPIDEMFKLSRHFADILAEVSPPAEVGSPASDDGSSQPARRLNSLSDPATCLFVLSTYVRLLDMYQKVFSCIHSELAQLESGKLFQSWKLPGVTVGSFAVDSTPSLQMSLTIQLAEEFLLQMRRATTSLDPALRSDSSSVGRASDTTSMFSGVVDVSFQALKRQEESLGKELKELRKAMESFLDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQF5</accession>
    <name>E3QQF5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">BZIP transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_08237</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697367">
        <property type="protein sequence ID" value="EFQ33093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097113.1">
        <property type="nucleotide sequence ID" value="XM_008098922.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQF5"/>
    <dbReference type="STRING" id="645133.E3QQF5"/>
    <dbReference type="GeneID" id="24413602"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08237"/>
    <dbReference type="eggNOG" id="KOG1414">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060558_0_0_1"/>
    <dbReference type="OrthoDB" id="295274at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14687">
        <property type="entry name" value="bZIP_ATF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051027">
        <property type="entry name" value="bZIP_transcription_factors"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19304">
        <property type="entry name" value="CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="7">
        <location>
            <begin position="227"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="359"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="252"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="26"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="47"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="128"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="156"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ33093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="385" mass="41357" checksum="FCA66CC12103F42C" modified="2011-01-11" version="1">MDYYSASGASTSEQSGLPARAASFKPTPNFSANSTDRTNLQQKEHGQQQQQQQQQQQQQQQRTQFLFSQQQQRLQQPIEPRASSSQSAFVSLSALNSARGAPPSVVDRHSSTSTQSSSGWPDSPVSNATDSLSSPTSSVISPPAPPIDPLLFDSAKGTERPQKEDASEAPKRRRGRPRLFDASSKTASAAVPTPTKVHKKSASRRTSTASASGVDEHADGHGASTVNDKKNRIRARNREAAYKCRQKKQKGIEELQTQEAVMENINKSLNSEAAQLRGEILMLKNMVLQHGGCGCPYIEDYISGAAQNLVQSSMAASASAAGGGMQMHSQDCRNGTGGGEYIDWKMFDMDTKAGMPSLESESGFSGYDDVASHSARAHSQGASMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQL6</accession>
    <name>E3QQL6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">D-glycerate 3-kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_08298</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the GLYK kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697368">
        <property type="protein sequence ID" value="EFQ33154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097174.1">
        <property type="nucleotide sequence ID" value="XM_008098983.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQL6"/>
    <dbReference type="STRING" id="645133.E3QQL6"/>
    <dbReference type="GeneID" id="24413663"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08298"/>
    <dbReference type="eggNOG" id="KOG2878">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056986_0_0_1"/>
    <dbReference type="OrthoDB" id="347435at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001691">
        <property type="entry name" value="Probable ATP-dependent kinase TDA10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10285">
        <property type="entry name" value="URIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SRP54-type proteins GTP-binding" evidence="11">
        <location>
            <begin position="36"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00061312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ33154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="295" mass="33206" checksum="F8DF1A7F7CA03341" modified="2011-01-11" version="1">MAPTASCIVDDKSPLCIPFIIGLLEKHSPQRGVRPFIIGLNGVQGVGKTTLVKKLAETLTKLGHTTLVFSIDDLYLRHEDQVAFARSHPDNLLVQQRGEPGTHDMQLAQTFFDSITSGKPTKVPSYDKAAFSGQGDRLPERQWVEVNSLGKPKVQVVIFEGWCVGFRALPDAVVEAEWKAPSKTLQRHKLEHLLLVNESLKGYDIMTDLLDAFIHIDAEDTQYVYGWRLQQEAALRRERGAGMTDEQVVKFVDGYYPAYELFSDNIKKGILPNSPGRQMRLVVDKDRRVKEHLVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQV7</accession>
    <name>E3QQV7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08389</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697368">
        <property type="protein sequence ID" value="EFQ33245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097265.1">
        <property type="nucleotide sequence ID" value="XM_008099074.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQV7"/>
    <dbReference type="GeneID" id="24413754"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08389"/>
    <dbReference type="HOGENOM" id="CLU_2637924_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178745" evidence="1">
        <location>
            <begin position="19"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ33245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="77" mass="8478" checksum="C6E67F61A9B102F7" modified="2011-01-11" version="1">MRLYTISTMALLFVTSIADDCICTKAGTERACKAAKGNMKGEYCSTSDASAFLTSLLQERIHKATKMRQIQKVEAII</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRE8</accession>
    <name>E3QRE8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA-processing protein 42</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_08715</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase PH family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697370">
        <property type="protein sequence ID" value="EFQ33436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097456.1">
        <property type="nucleotide sequence ID" value="XM_008099265.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRE8"/>
    <dbReference type="STRING" id="645133.E3QRE8"/>
    <dbReference type="GeneID" id="24414080"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08715"/>
    <dbReference type="eggNOG" id="KOG1612">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046570_0_0_1"/>
    <dbReference type="OrthoDB" id="272245at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035925">
        <property type="term" value="F:mRNA 3'-UTR AU-rich region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034473">
        <property type="term" value="P:U1 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034476">
        <property type="term" value="P:U5 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050590">
        <property type="entry name" value="Exosome_comp_Rrp42_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097:SF8">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097">
        <property type="entry name" value="EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0271">Exosome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="8">
        <location>
            <begin position="36"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="73"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="283"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="87"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00042523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ33436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="383" mass="40358" checksum="610FDE981292C18C" modified="2011-01-11" version="1">MASAQQVLLSPAELAYLHSSLSLTPPIRPDGRKANQFRPLTAETGILPGTNGSARVCFSDGTEAIVGVKAEIEKTRVPPGAETDGEATEKRTEGGDGETRGNNDWLEMTVEIPGSRDDDAATVFLSNMLSEALLADGEFTKKLRINNRFHWKLYLDILLISPPLSYPLPLLSLTTHLALLATRLPRLKSEGDEDPMFDDDWEASTFLYPRDGSAPVTGSRPPITLLVIAVGGNIIFDPAREELAVAESALAVSVAEEKTAASAGGMDVDGRQLKLLAVRTVDPPSRLTAPGVPNSANPATGLAGTPSKAPPAPPAGEDKAAEGVWRPPIGGTKLHVLEGMIFQGTREGRHCGRGARGDCRGGLGLGAAGYGSRFAARQDGKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRT5</accession>
    <name>E3QRT5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein N-terminal and lysine N-methyltransferase EFM7</fullName>
            <ecNumber evidence="5">2.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Elongation factor methyltransferase 7</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">EFM7</name>
        <name evidence="7" type="ORF">GLRG_08852</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono- and dimethylation of 'Lys-3'.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM7 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="GG697371">
        <property type="protein sequence ID" value="EFQ33573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097593.1">
        <property type="nucleotide sequence ID" value="XM_008099402.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRT5"/>
    <dbReference type="STRING" id="645133.E3QRT5"/>
    <dbReference type="GeneID" id="24414217"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08852"/>
    <dbReference type="eggNOG" id="KOG2920">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032409_0_0_1"/>
    <dbReference type="OrthoDB" id="46564at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071885">
        <property type="term" value="F:N-terminal protein N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000183">
        <property type="term" value="P:rDNA heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03223">
        <property type="entry name" value="Methyltr_EFM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025784">
        <property type="entry name" value="EFM7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF10">
        <property type="entry name" value="PROTEIN N-TERMINAL AND LYSINE N-METHYLTRANSFERASE EFM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51560">
        <property type="entry name" value="SAM_MT_NNT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5 7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="84"/>
            <end position="86"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ33573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="284" mass="31199" checksum="6B41796E1773D36B" modified="2011-01-11" version="1">MSPVSDVADGDTGDLFADPEDYYPPTPPPTTQTHTLSSGRVLTLHLVGYSPTEAHHLWNGSRVVSDYFEADPSRVRGRAVLELGAGAGLPSLTAGILGARRVVVSDFPDADIVQTMQKNVDEAGDLEGVVVPRGYVWGADVAPLLEVLAEPEFTTTTTTTTTTTTTTTTTTTTTTTTARRFDVLVLADLLFRHSEHGKLVDTIWNALARERGAVAYVFFTSYRPWLRHKDLAFFDAARERGFLVEQVLERKMEKPLFEGDPGDVEVQKTVSGFEVRWPEELLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRY0</accession>
    <name>E3QRY0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08547</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697372">
        <property type="protein sequence ID" value="EFQ33618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097638.1">
        <property type="nucleotide sequence ID" value="XM_008099447.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRY0"/>
    <dbReference type="STRING" id="645133.E3QRY0"/>
    <dbReference type="GeneID" id="24413912"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08547"/>
    <dbReference type="eggNOG" id="ENOG502SIE8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004184_7_4_1"/>
    <dbReference type="OrthoDB" id="2157530at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF73">
        <property type="entry name" value="HET DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G01020)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26639">
        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="65"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ33618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="612" mass="69645" checksum="0DE3D8A9DBC92E8E" modified="2011-01-11" version="1">MAVTINPMSSSGEAQGIAYRALDHTTYEFRLLYLKPTAAEHENPSHDDRVIGELQHFSLSGSPSFVALSYCWGQSGAESPIVIDGTMLKSGSNAEAALQHLRNAVGVYVWIDQLCINQSDNAEKGHQVRMMRQIYTAATRVAVWMGPPGDDIDLFFSHTRAMSALVREEKYIDVVRAHADIAFLQRVSHAFRAFCKRDYWTRVWIIQEFAVAVELDILCGHEEEDQEVMKTLVEMLRGFKTQENSFLEGVFTRRRRYQLRYGDPSARLATRAISEVENGMMNGSESLFAVLVTTLVMEIDYNQPKSTDHRDRVFAVMHFADDVAEFEGLSNYSLSCEQVYQNVGRRILLQGNIDVLSYCQFPRDKPLATWAPDWRMGIRRPNNGNPWRSRFDAPKAPFQEQGVLTPDKKTVQLRGVLVDAVAETGNVWDPNWVEELDCKAALEYLDNVENLCKKSPMFAEKIKVQDFKDVIRICIADHYHYKEPERQAELLEGFAQAVVWMGRGAGKFAAEMAEMGIRMDDAIGWQQPWFMFALKNLHSRRPFLSASGYVGLAPMHARPGDKIVIFLDGKTPYAIRGTEEGFYEVVGELYVHGIMYGEFMTDGVEIREFMLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QS84</accession>
    <name>E3QS84_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08855</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697373">
        <property type="protein sequence ID" value="EFQ33711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097731.1">
        <property type="nucleotide sequence ID" value="XM_008099540.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QS84"/>
    <dbReference type="STRING" id="645133.E3QS84"/>
    <dbReference type="GeneID" id="24414220"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08855"/>
    <dbReference type="eggNOG" id="ENOG502S62B">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044999_1_1_1"/>
    <dbReference type="OrthoDB" id="542013at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052228">
        <property type="entry name" value="Sec_Metab_Biosynth_Oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47534:SF3">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE-LIKE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47534">
        <property type="entry name" value="YALI0E05731P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ33711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="295" mass="32890" checksum="8F49DC6DAB62832F" modified="2011-01-11" version="1">MTTRALVIGGTSGIGYAMACRVAASSPSSSVVISGRTQPDNMPHANMEFRPIEATSMREIKGFTDNFKQQQVPAEEKNKLDLLIMTQGVMTMAGRTETPEGIDRKMALHYYGKQLLIRELMPALKEDARVVIVYDSWTGNMDKVRWDDLDLKTHFSLGAAANHCQVMNDVMVQWYAARQQQQKQAEAATGRHFVHAWPGGVNTEGLMREMPWVLGATAKLLAPLITVTPAKCAEYLMDGVDKVTAPPTVNKEDERFWHYIDNKGRVLPNKPVCTEEQMGKIADHTWKLIDAALEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QT44</accession>
    <name>E3QT44_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_09176</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697375">
        <property type="protein sequence ID" value="EFQ34032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098052.1">
        <property type="nucleotide sequence ID" value="XM_008099861.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QT44"/>
    <dbReference type="GeneID" id="24414541"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09176"/>
    <dbReference type="eggNOG" id="ENOG502R9QS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1602605_0_0_1"/>
    <dbReference type="OrthoDB" id="4851264at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12087">
        <property type="entry name" value="TM_EGFR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="39"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ34032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="159" mass="16822" checksum="9AB1DA01F3603FE8" modified="2011-01-11" version="1">MPAVHINTANVAREIEGLVIRTTSRSGSTFNSTHKTVRVIGGGIIAAIVIGAVIFIALVLICAFCLLRRHKRQSARRQQEMEKYYGESRSSSGTDVPTGPAPGQEGYGNSNKGYGYGQGTGYGYAHTAQPGQADYGTQNTGGVSPMAPAYTAEHVTSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QT45</accession>
    <name>E3QT45_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NCS1 nucleoside transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_09177</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697375">
        <property type="protein sequence ID" value="EFQ34033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098053.1">
        <property type="nucleotide sequence ID" value="XM_008099862.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QT45"/>
    <dbReference type="GeneID" id="24414542"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09177"/>
    <dbReference type="eggNOG" id="KOG2466">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021555_3_0_1"/>
    <dbReference type="OrthoDB" id="2018619at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015205">
        <property type="term" value="F:nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11482">
        <property type="entry name" value="SLC-NCS1sbd_NRT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4160.10">
        <property type="entry name" value="Hydantoin permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045225">
        <property type="entry name" value="Uracil/uridine/allantoin_perm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30618">
        <property type="entry name" value="NCS1 FAMILY PURINE/PYRIMIDINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30618:SF15">
        <property type="entry name" value="NICOTINAMIDE RIBOSIDE TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="276"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="328"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="359"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="392"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="438"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="479"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ34033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="555" mass="61447" checksum="DC0EBF816A57D0FD" modified="2011-01-11" version="1">MARRLLERFRVRDDTEHGYETTKWINPDIAPLPPSRRTWGLWAFLGFGSISNLCISAWTGAASLLSLGLTIPQTIGLMIIARVLICLLVIGNGWMGSEWHIGFTVSQRIILGMNGAYIGQLIRIMLSIVWYGSQAWLGGLCVSAMLSSWSYDFLMMRNTLPESAHMVTRDLVGFVIFHLISVPFLFIRVEKAKIPVIIANLIVFVAMMGITIWACNTGGTGPLFETGAKQASMLSKEWAWVYGIIASVGNISAGILNQSDFTRFARRQGIQVPGIVFSLFIPGMIVPIFAILTASASMAIWELEEPMWNPLTVITQWMMDDYNSQSRAGAFFCSLGFVLGQVAENILGNGYAAGMDLAGLVPTWITIRRGALLAAALSWAVQPWEFYNTASVFVAVAASFSVFMGPLTGIMMTDYFIIRRQKIEVSQLYTGSKDGAYWYFYGFNWRAFVAWVVCFVPAMPGMIAAVNPGVRINDGLYKYYLGNYIFGFLEAGTLYAILTFAFKPPRLGYQDHIDIYGAFEDNVAVKKGMAPFENPKTVNGPVEVIPVDKGDNTRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUL9</accession>
    <name>E3QUL9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="13">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_09701</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
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        <property type="protein sequence ID" value="EFQ34557.1"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
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    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
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    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
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            <begin position="31"/>
            <end position="51"/>
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    <feature type="transmembrane region" description="Helical" evidence="10">
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    <feature type="transmembrane region" description="Helical" evidence="10">
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            <begin position="490"/>
            <end position="514"/>
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    <feature type="transmembrane region" description="Helical" evidence="10">
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            <end position="551"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
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            <end position="923"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
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            <begin position="943"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
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            <begin position="1045"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1127"/>
            <end position="1150"/>
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    </feature>
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            <begin position="279"/>
            <end position="549"/>
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            <end position="846"/>
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            <end position="1479"/>
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            <begin position="848"/>
            <end position="885"/>
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        </source>
    </evidence>
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    <sequence length="1486" mass="162671" checksum="0351964F8876A3E2" modified="2011-01-11" version="1">MGSICLNDDSFGPAVRGCRDDFDFTVRFESIFLSIIPAAVFTAVSLPRIVYLSRKPRIVSAKSIETIKLAIITVFATLQFALLIVQTTSNGSLDGFAAAASALSFLASLFMIGLSFAEHSRAPRPSMLLTGYIFFQILFDVAQARTSWLMARTSLSTQLFARLFTASLAVKVVILLVEAQRKARWIRWTAEEHSPEETSGLFSLSVYFWLNRLFLHGYKKVLTIKDLYALDRGMIAETMQVTLAQELDKGTYRGRKHGLARALAKSLAVPLMLPVVPRLALIGFSYSQPFFIQSLLVYLQEDPETTPKNMGYGLIGAAFFIYAGIAVSTALYYYFHQRVLYMSRGCLAAVIYKKTTEASISGAGDDSAAVTLMSTDIERIIRGFYPLHECWASFLEIALGCWLLQKKLGIAFIAPIAVILVCTGITAAAAKLTGERQSRWMAQIQKRVGHTSNIISNMKHLRISGLAGIVGDLIQKMRVEEMRIGNQFRWLLIVSALGALSPAIVSPAVTFAFAQSRLDVTTIFTSFSFLVLLNAPLGMLFQAVPGLIAGFTCLGRIQKFLEADPRVDFRQSAHSSAPNDKQSEETAYRDSLEGIPLESVGKAADQSSERCASGPAIAIVDGSFGWSAEKMVLQDITASVPASQLTIVVGPVASGKSTLCKVFLGEVPFSSGLVSVLSRNAAIGYCEQNPFLSNGSIKDNIVGFSPFNQARYDEILDACMLSKDLLLLPYGDDTKIGSNGIMLSGGQKQRVSLARALYLNSNLLIFDDILSGLDNDTSAEVFRKVFGVDGIIRRRRATAVLCTHAIKHLPLADHIIALGPDGTLVEEGTFEDLMRDNKYVASLGVKATDSDTDSESGSISDRKPDPLPPPKAKRTPAISEDMMEKSRQTGDFKVYIHYLRSLSIPATVIFVLGSASYAIWNTFPTMWLKYWAEDTLGKSSQYYAGLFGFFKALQLLSLVVGGVALIIYMTTSSGEALHQQALRTVIHAPLTFFTNTDTGIVTNLFSQDMTLIDSELPMSVLNAVMSGFEAIGMGVVIAVGSPYMAVSYPFLVAFCWIIQKFYLRTSRQLRLLDLESKSPLYTHFLDTIKGVATIRAFGWTDKNIDFNQHLLDTSQRPAYLLAMIQQWLVVTMQLMVACIAVVLVGLAVGLRASSGFTGASLVTLMTWGETIAWLIRCYTQLETSIGAIARIKTFSEKVTPEDLEGEDIDLPEEWPANGQIDIKGVSASYSNEQQTSSEGIVTPPSLALKDLNFSVQPGQKVALCGRTGSGKSSLILLLLRLLDPVSTCSQNIEIDGVPFHRIDRSTLRGRIIAVPQDAVFLPDGSTIKSNLDPFEAASDAECLSVLRAVQLAGFVEEQGGLHEGMSADSLSAGQKQLFSLGRAILRRRMKDARSKRRGGGILLLDEVSSSVDHATDRLMQEIIKEEFAQYTIVMVSHRLELVVDFFEAVIVMDQGRVIETGSPPELVNTRGSRFGELWAIENQGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUS6</accession>
    <name>E3QUS6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA recognition domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_09758</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697382">
        <property type="protein sequence ID" value="EFQ34614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098634.1">
        <property type="nucleotide sequence ID" value="XM_008100443.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUS6"/>
    <dbReference type="STRING" id="645133.E3QUS6"/>
    <dbReference type="GeneID" id="24415123"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09758"/>
    <dbReference type="eggNOG" id="ENOG502S19D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074138_0_0_1"/>
    <dbReference type="OrthoDB" id="7763451at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32343:SF10">
        <property type="entry name" value="RNA-BINDING REGION RNP-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32343">
        <property type="entry name" value="SERINE/ARGININE-RICH SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="4"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="70"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="218"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="250"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ34614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="279" mass="29963" checksum="D6F1AFBCF93C73B6" modified="2011-01-11" version="1">MSNTTVYVKNIASATEDKEIKDFFSFCGKITNIEVTPSGETKDAAVTFEKETAAKTALLLNNTQLGTSHITVTSAGGDPTDDAPHHKENASRDSDDITQEEKPRSRILAEYLAQGYVVGDAALQRAIELDSQHGVSNRFFSTLQSLDQKYHATDRAKATDQSYGITAKAQGIFGGLSSYFEKATSSPTGKKIVGFYETGSRQVQDIHTEARRLADLKKEEHGGSALKASGLERFLGKEKEKSVPPATGETIGTQSPTNPDPTTAVPLSKPSAATDEKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVI1</accession>
    <name>E3QVI1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">linoleate 8R-lipoxygenase</fullName>
            <ecNumber evidence="3">1.13.11.60</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_10013</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(9Z,12Z)-octadecadienoate + O2 = (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate</text>
            <dbReference type="Rhea" id="RHEA:25395"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:30245"/>
            <dbReference type="ChEBI" id="CHEBI:58659"/>
            <dbReference type="EC" id="1.13.11.60"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.60" evidence="3"/>
    <dbReference type="EMBL" id="GG697385">
        <property type="protein sequence ID" value="EFQ34869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098889.1">
        <property type="nucleotide sequence ID" value="XM_008100698.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVI1"/>
    <dbReference type="STRING" id="645133.E3QVI1"/>
    <dbReference type="GeneID" id="24415378"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10013"/>
    <dbReference type="eggNOG" id="KOG2408">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002329_1_0_1"/>
    <dbReference type="OrthoDB" id="823504at2759"/>
    <dbReference type="BRENDA" id="1.13.11.60">
        <property type="organism ID" value="1570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052878">
        <property type="term" value="F:linoleate 8R-lipoxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20612">
        <property type="entry name" value="CYP_LDS-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09817">
        <property type="entry name" value="linoleate_diol_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.640.10">
        <property type="entry name" value="Haem peroxidase domain superfamily, animal type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019791">
        <property type="entry name" value="Haem_peroxidase_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037120">
        <property type="entry name" value="Haem_peroxidase_sf_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050783">
        <property type="entry name" value="Oxylipin_biosynth_metab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034812">
        <property type="entry name" value="Ppo-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11903">
        <property type="entry name" value="PROSTAGLANDIN G/H SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11903:SF37">
        <property type="entry name" value="PSI-PRODUCING OXYGENASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03098">
        <property type="entry name" value="An_peroxidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50292">
        <property type="entry name" value="PEROXIDASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5 11" id="KW-0349">Heme</keyword>
    <keyword evidence="9 11" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="11">
        <location>
            <position position="380"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR619791-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ34869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1128" mass="126871" checksum="7040D559EDE0198F" modified="2011-01-11" version="1">MSQAQDQYPKHQPALAEKLAAVRDVLQKSISPIPLYPGPTPGGAGQEAEPTNLVQDVKNLGFEDFDTLADFLGSAVKGQINDNDLLLERLIELFAKLPSGTVKGKKLEYGLINQLWNGIDHPPMTTLADEYKYRAADGSNNNIHSPKMGAAGTAYARSTPAITYQTPSQPEPSLIFDMLFARGDEFKPHPNKLSSVLFYFATIITHDIFQTDGQSSNINQTSSYLDLAPLYGRNQKEQDDVRTKLDGRLKPDSFSSKRVLGFPPGVGVLLIMFNRFHNYVVTQLASINENNRFTRPTGPRMAWIKYDNDLFQTARLITCGLYVSIVLRDYVRTILNMNRTASSWALDPRTNEGKSLLRAETPEGTGNQVSVEFNLIYRWHCAISPKDDKWTQETFAKVLKDPEDPNKKIEDFTLKDFGHAIRDWELRIPNDPVERGFADLRRGKDGSFREEDLARIFKESVEDVAGSYGANRIPEIMKPIELLGIINARKWNVATLNEFRKHSGLTPHPTFEDINPDPEVVKKLRYLYGTPDQVELYPGLVSEKAKPAMAPGSGLCGNFTMTRAILSDAVALVRGDRFYTIDYTPKNLTNWGFNQTSHDPNVDQSHVFYKLVYRAFPNSFKANSIYAHYPLTVPSENRKILESIDRAYLYSWDEPETKASIIPIFSHKAISDILYNQADFKVIWGEAIRHLVAQPGKDYSKNFCLSGDGKANLLNRTQVRKALISGPWEQEVWKWYTHMTPRLLEQHSFAIRKGVKEVDIVRDVINMTNTRFNAALFCLPIKNEDSPWGIYTDQELYMVVATLFQLVFLNADIANSFKLQTIARELAQGLGKIMTLVVQTIAKAGLITDIVAKIREGEASLPTFGNHLIERLIADGKDLDEVIWGTILPVITANVTNQSQITAMCIDYYLGEGKQYLGDLYHLAHQNTPEADEKLMKYMLEGCRLRAAVAVYREAATDQVITDYAPCLLDPNDPTSRKPVVNDDIEGTKYEVKIPKGQRVICNLMTAGRDPTIFESPSEVRLDRPLESYVHFGLGPHWCAGKEISRVAQTSLFKQIVGLKNLRRAEGERGNIKNMPAGAWKGQVGLPVGSQNGVGKSHEPWLGLRAFMTADQSSFWPVPTTMKVEWDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVT8</accession>
    <name>E3QVT8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10120</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697386">
        <property type="protein sequence ID" value="EFQ34976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098996.1">
        <property type="nucleotide sequence ID" value="XM_008100805.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVT8"/>
    <dbReference type="GeneID" id="24415485"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10120"/>
    <dbReference type="eggNOG" id="ENOG502RNJ4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1586349_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="168" mass="18983" checksum="A9102F950B93A160" modified="2011-01-11" version="1">MHNTKQKSGSSHKTSSRSCRSSKHGSSGSVSPSSSNQQQQVPRTIIAQYVESDRHLPSTQNWQQHSNNVGSRDSTTGSANDRYSGHNDDYRSYDVQRSYQVRREHAINLPGPAPPPRQRATPEEQLRAYDSRFGGYHSTIMAPTQYSYPQDLDLDSSEMPNNNPRRDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>E3QW58</accession>
    <name>E3QW58_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fungal specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_10236</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697388">
        <property type="protein sequence ID" value="EFQ35092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099112.1">
        <property type="nucleotide sequence ID" value="XM_008100921.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QW58"/>
    <dbReference type="STRING" id="645133.E3QW58"/>
    <dbReference type="GeneID" id="24415601"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10236"/>
    <dbReference type="eggNOG" id="ENOG502SJFF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006632_3_0_1"/>
    <dbReference type="OrthoDB" id="1924787at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001080">
        <property type="term" value="P:nitrogen catabolite activation of transcription from RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF4">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN DAL81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="19"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="53"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="69"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ35092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="642" mass="72101" checksum="1C2C37CEA4413DC5" modified="2011-01-11" version="1">MESPNRNRTRKSSHRNSHPCDFCRYKRAACLLHHQPPCELCKRLDKDCTFVGEPNKRRRISDPRRLSDSSHVVVSHHQSQSPSDIGMRSPFTETNSPGNEANFGKDVADSTSPNSLHAENHLPDTFPRDVPPSPSSLDATPGYNAQAIGLSGESDPYLLHLYRFDEKNECTFQQLRIRNVGLNDGTPTQFMLQNNSLARKAQPEGLAGGESDLRSEVADMIPEGVGKRLINLFWRYVQPYFPILSREQVIQETDTKPSSLPVCLLAAIYGHALPFCVFDDKLCVDVDTLPSADRLFKLAWMAALSLFHTPSLAVVQTMLLMIQRRPTNKHVADTPFKWVMLADTVALAQCLGLNLDPTDWSIPSWEKRLRRRLAWAVIVQDQWLSLNFGRSSHIQECDWDVSSLRADDFESMPEVDGDAPAFNHFLQLASLTEIVSKIQRHMFSVKATRVLSKSLEATFEVARPLRMELAQWLQDRPDVADQPSTCVPHHGLDGNGSIKLAYITAKISVFKALLRPKNTEAPIEARMALRTGAMAVAREMYDFLVRLEAHHLEAFWHSYSRVNFAIASNFIVLLFALSPSPADADESLTLLTRWRGLLRIKSRSCDLLNLSLLRLDAMFVAGLGKLIELTPSASEAASNRNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXA5</accession>
    <name>E3QXA5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10637</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697394">
        <property type="protein sequence ID" value="EFQ35493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099513.1">
        <property type="nucleotide sequence ID" value="XM_008101322.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXA5"/>
    <dbReference type="STRING" id="645133.E3QXA5"/>
    <dbReference type="GeneID" id="24416002"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10637"/>
    <dbReference type="eggNOG" id="ENOG502RH53">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_723637_0_0_1"/>
    <dbReference type="OrthoDB" id="5230713at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="377" mass="41529" checksum="3AC40B67E968B654" modified="2011-01-11" version="1">MPTNSKSSSSSRMTSELNNMGVLSASTLGKAAPFLAALEQQLYQSIVPRRSSKGSAVPVDEAINMSRKQQTADSYNNDDDEGSDLSYYFRVPYEADGAIHQKDEAEEGELEEETSPESEKRRSDAAEAFWFLRDFIEARWPVQLLAGYIKIQCDLTLDEIKELGRLNKAEGSRKCRKLISAPVIHDEIGYALWSELAREIAARGDAPGDDFQVIKAAPASAGLTKAMTSPAAMSKITAEEVASRRARSMRRRATDGDAITVRSRPGTASTHVSTTARRRRKSDVQLVRPHQVICTTCGSRAVPRPKDDDDDDYGDDDSTVSDDEYEHDHEEDELGSRERKRDSISRRLSVKMNKTLTKLGEGLATGYGGNGVSRVTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXJ2</accession>
    <name>E3QXJ2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">GLRG_10724</name>
    </gene>
    <organism evidence="20">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 21">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the DEAD box helicase family. DDX48/FAL1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="GG697396">
        <property type="protein sequence ID" value="EFQ35580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099600.1">
        <property type="nucleotide sequence ID" value="XM_008101409.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXJ2"/>
    <dbReference type="STRING" id="645133.E3QXJ2"/>
    <dbReference type="GeneID" id="24416089"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10724"/>
    <dbReference type="eggNOG" id="KOG0328">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_1_0_1"/>
    <dbReference type="OrthoDB" id="10265785at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18045">
        <property type="entry name" value="DEADc_EIF4AIII_DDX48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000031">
        <property type="entry name" value="Eukaryotic initiation factor 4A-III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000498">
        <property type="entry name" value="Eukaryotic initiation factor 4A-III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 15 19" id="KW-0347">Helicase</keyword>
    <keyword evidence="6 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="18">
        <location>
            <begin position="27"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="16">
        <location>
            <begin position="58"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="17">
        <location>
            <begin position="239"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="14">
        <location>
            <begin position="27"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00037945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EFQ35580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="401" mass="45611" checksum="F177B60076A43A04" modified="2011-01-11" version="1">MAEGSGIDRKAEERMEFSTSKEVTVHPTFESMSLKENLLRGIYAYGYESPSAVQSRAIVQVCKGRDTIAQAQSGTGKTATFSISMLQVIDTAVRETQALVLSPTRELATQIQSVVMALGDYMNVQCHACIGGTNVGEDIRKLDYGQHIVSGTPGRVADMIRRRHLRTRHIKMLVLDEADELLNRGFREQIYDVYRYLPPATQVVVVSATLPYDVLDMTTKFMTDPVRILVKRDELTLEGLKQYFIAVEKEDWKFDTLCDLYDTLTITQAVIFCNTRRKVDWLTDKMREANFTVSSMHGDMPQKERDSIMQDFRQGNSRVLISTDVWARGIDVQQVSLVINYDLPSNRENYIHRIGRSGRFGRKGVAINFVTSEDVRILRDIELYYSTQIDEMPMNVADLIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXQ9</accession>
    <name>E3QXQ9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">WD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_10806</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697397">
        <property type="protein sequence ID" value="EFQ35662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099682.1">
        <property type="nucleotide sequence ID" value="XM_008101491.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QXQ9"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_001285_0_0_1"/>
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    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
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    <dbReference type="GO" id="GO:0030897">
        <property type="term" value="C:HOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
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        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0009267">
        <property type="term" value="P:cellular response to starvation"/>
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        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0034058">
        <property type="term" value="P:endosomal vesicle fusion"/>
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        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16448">
        <property type="entry name" value="RING-H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
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        <property type="entry name" value="Beta-prop_Vps41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000547">
        <property type="entry name" value="Clathrin_H-chain/VPS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045111">
        <property type="entry name" value="Vps41/Vps8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12616">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING VPS41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12616:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 41 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23411">
        <property type="entry name" value="Beta-prop_Vps41"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23556">
        <property type="entry name" value="TPR_Vps41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00299">
        <property type="entry name" value="CLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50236">
        <property type="entry name" value="CHCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Vps41 beta-propeller" evidence="5">
        <location>
            <begin position="221"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="Vps41 beta-propeller" evidence="5">
        <location>
            <begin position="427"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="3">
        <location>
            <begin position="961"/>
            <end position="1121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="180"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="499"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="616"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="59"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="192"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ35662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1332" mass="146789" checksum="AC3D151EBBB2F193" modified="2011-01-11" version="1">MTDASDPDRDPSTAAQKGKESDNAGEIVGVSVGAPAETVVSKVEQGVTEGDAAHRDKEDEGDDDDEEEEEEDSGEDDEDEDEDDEDEDDEDEEPRLKYARLTQHLGPIYRNGDATSSFLVAGDKMIIGTHNGNIHVIQLPVFQSLRVYHAHSASVTSISISPNPPPLPTARSEAVQRLAAEAAETVAKQRPVSRQSGTSPAAASRRPKEPSPVPNIPSNNLHIATSSMDGNVCIFSLVDTKDIQLRNFARPVQAVALSPDYKNDRTYLSGGLAGQLILTSGGQPGRSTSTTVGTAAATASGWLGSMGLGTNTGKDVVLHSGEGTISTIKWSLSGKYVVWLNEHGVKIMRSKLHLESSDADDAWKRIGHVDRPQTDEWETMASVWKGRVEWIDEQAVETEDDEAGRTDVAASAATESLRQASASSTKKIERLLVGWGGTIWIIHVHPGSVGTGKRAGEKSIGRAEIAKHLRMDCIISGISLYTQNLLLVLAYVLPDDDEDSDGGDDDKVVKGHKSKISSTSAGSEPSGGIKRRQNNLPPELRLIDLTSQAEIDKDGLSVSRYERLTSGDYHLGVLPAQNAASAVASSKGALDAITGFGSDMWNAAINPKSLFSSGASIRSGHSGDGVSSTQVPSSAGGGRKLGTPTVHPNLVKPGVKIFIHSPFDFILATKRDLGDHLGWLLEHQEYQKAWELLDEHPEIMVSPPENLHELVPETPDGKQSSQEDLLDDASSVMGSSGMARQPNSSAQRKKRHIGELWIRELIEAGNWAEAGKVCGKVLGSSDRWEKWVWTFAGADKFDQITDYIPSEPMYPPIPGTIYEVVLNHYIQVDKLRFRELLDRWSTDLFDIKTVTTALDNQLKYRDVREDSIEGGQKGRDWKIVMESLARLHEANGRFRESLKCYIKLQDADSAFRLIRDNHLAEAVTDDIPGFIGLRVPNDKREFLSEADLEEATSEAITLLADEAQHGLVKPSVVVSQLQAQNLRLYLFFYLRALYKGEGIEEHSGETRDRLLMDSQSQVDEFADLAVELFAQWEQPLLMSFLKSSTSYKFEKAVQECEKYKYYDELVHLYSKIGEMKRALYLIIDRLRDVKKAIEFAKQQDDPDLWDDLLDYSMDKPSFIQGLLEEVGTAINPIKLVRRIPEGLEIQGLREGLKHIMKEHEIQYSISLGVARVLRSEVAAAQNDLRSGQRKGIKFAVVVQSADHVDVQVKDVVHPPVSAEQIEESFFKAPKAEQPGHIHEPPKPGHCAQCRESFTEYEMETLVGFACGHVFHLSHLLEMLFPGKRQEDDYGINSEEAINSGCRVGSKVTHARLLKDRIREGCPVCKHVVEVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QY87</accession>
    <name>E3QY87_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial</fullName>
            <ecNumber evidence="15">7.1.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">GLRG_10934</name>
    </gene>
    <organism evidence="19">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="function">
        <text evidence="15">Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 15">
            <text>a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29091"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.1.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 15">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 15">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="14">Complex I is composed of about 40 different subunits. This is a component of the flavoprotein-sulfur (FP) fragment of the enzyme.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="15">Mitochondrion inner membrane</location>
            <topology evidence="15">Peripheral membrane protein</topology>
            <orientation evidence="15">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the complex I 51 kDa subunit family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.2" evidence="15"/>
    <dbReference type="EMBL" id="GG697401">
        <property type="protein sequence ID" value="EFQ35825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099845.1">
        <property type="nucleotide sequence ID" value="XM_008101654.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QY87"/>
    <dbReference type="STRING" id="645133.E3QY87"/>
    <dbReference type="GeneID" id="24416299"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10934"/>
    <dbReference type="eggNOG" id="KOG2658">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014881_1_0_1"/>
    <dbReference type="OrthoDB" id="42889at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1440.230:FF:000001">
        <property type="entry name" value="Mitochondrial NADH dehydrogenase flavoprotein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.600:FF:000001">
        <property type="entry name" value="NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11540:FF:000001">
        <property type="entry name" value="NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11540">
        <property type="entry name" value="NADH-ubiquinone oxidoreductase 51kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.230">
        <property type="entry name" value="NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050837">
        <property type="entry name" value="ComplexI_51kDa_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001949">
        <property type="entry name" value="NADH-UbQ_OxRdtase_51kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011537">
        <property type="entry name" value="NADH-UbQ_OxRdtase_suF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011538">
        <property type="entry name" value="Nuo51_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037225">
        <property type="entry name" value="Nuo51_FMN-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019575">
        <property type="entry name" value="Nuop51_4Fe4S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037207">
        <property type="entry name" value="Nuop51_4Fe4S-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054765">
        <property type="entry name" value="SLBB_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01959">
        <property type="entry name" value="nuoF_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010120">
        <property type="entry name" value="PRK13596.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11780:SF10">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11780">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE FLAVOPROTEIN 1 NDUFV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01512">
        <property type="entry name" value="Complex1_51K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10589">
        <property type="entry name" value="NADH_4Fe-4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22461">
        <property type="entry name" value="SLBB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00928">
        <property type="entry name" value="NADH_4Fe-4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142019">
        <property type="entry name" value="Nqo1 FMN-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142984">
        <property type="entry name" value="Nqo1 middle domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140490">
        <property type="entry name" value="Nqo1C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00644">
        <property type="entry name" value="COMPLEX1_51K_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00645">
        <property type="entry name" value="COMPLEX1_51K_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 15" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="15" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6 15" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 15" id="KW-0288">FMN</keyword>
    <keyword evidence="10 15" id="KW-0408">Iron</keyword>
    <keyword evidence="11 15" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="15" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12 15" id="KW-0520">NAD</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="15" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="9" id="KW-1278">Translocase</keyword>
    <keyword evidence="15" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding" evidence="17">
        <location>
            <begin position="359"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="456"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00063883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU364066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM00928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EFQ35825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="477" mass="52180" checksum="C926C87980BB196C" modified="2011-01-11" version="1">MATPRRLPAQAAQAARNYATVRTYGGLKDQDRIFQNLYGRMPPTLASAKKMGDWHKTKEIILKGHDWIISEVKASGLRGRGGAGFPSGLKWSFMNFKDWDKDDKPRYLVVNADEGEPGTCKDREIMRKDPHKLIEGCLVAGRAMNASAAYIYIRGEFVHEAAVLQNAINEAYKDGLIGKNACNSGYDFDVFIHRGAGAYVCGEETSLIESLEGKPGKPRLKPPFPAAVGLFGCPSTVANVETVAVAPTICRRGGNWFAGFGRERNQGTKLFCISGHVNNPVTVEEEMSIPLRELIDKHCGGVRGGWDNLLAVIPGGSSTPILPKNVCDNQLMDFDALKDSQSGLGTAAVIVMDKSTDVVRAISRLSHFYAHESCGQCTPCREGSKWTDQIMKRFEKGQGRPREIDMLQELTKQVEGHTICALGEAFAWPLQGLIRHFRPELEKRMEEYAAQNGGANALGGGWAPDSRAQGKLVSPGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYF1</accession>
    <name>E3QYF1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">chitinase</fullName>
            <ecNumber evidence="4">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">GLRG_11080</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="4"/>
    <dbReference type="EMBL" id="GG697402">
        <property type="protein sequence ID" value="EFQ35889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099909.1">
        <property type="nucleotide sequence ID" value="XM_008101718.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYF1"/>
    <dbReference type="STRING" id="645133.E3QYF1"/>
    <dbReference type="GeneID" id="24416445"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11080"/>
    <dbReference type="eggNOG" id="KOG2806">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010456_0_0_1"/>
    <dbReference type="OrthoDB" id="73875at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF333">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 11 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180942" description="chitinase" evidence="14">
        <location>
            <begin position="33"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="15">
        <location>
            <begin position="116"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="695"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1050"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="596"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="699"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="720"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="1051"/>
            <end position="1065"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EFQ35889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1094" mass="120205" checksum="532CDD9CF1237717" modified="2011-01-11" version="1">MLIFFKMRLSLLTQSLLFHNSLLDELFQLAHATQTLHVRMQHAAVPTACVATHQRSVARVTAPPTVMQKLSADNTAKMAPKNAHLVCAVLNLGCQKEFGGCGNVTRPSCSGNSVSKRTIGYYEAWSNTRSCQAVSPEDLNLNGFSHINFAFAFFDPKTFQIAPMDTETGKLYSRFTALKNNNAGLEAWISVGGWSFTDPGPTRTAFSDMTSTAENRKKFISGLIDFMEHYGFDGVDLDWEYPQADDRGGVTADKKNYALLTKELRAAFGSRYGISMTLPTSYWYLQHFDLESIQANVDWFNFMAYDLHGTWDAASKFVGPYLAPHTNVTEIDMGLDLLWRAGVKPAKVILGLGWYGRSFTLSDPSCNKPNGVCQFSGGAQPGLCSNASGILTLQEINEVIDYNDLKPVWDKEAMVKWITWDDNQWVSYDDDDTFEQKRKFANSRCLGGTMVWAMDQRDQGEDNGLAPASGVTTGQQQDAQEMAQGLAAGVSCYTSDCGASCKKGTNPVTQMNGQPGMLSTSDRCDKNQYRTLCCDDGTTIGTCKWRGYRGLGLSCMGGCDDEETEILQDTNNHSKNGDQTCTGGIQSYCCKGFESAPTKEELEEEAKEKAEELAEEAAEQAALDIAAKAFCRVAIPALLAPLELIEAAIPIIGEILDIAEIAATPALIQLCTSGIEKEGKAIFKVFGKEHSVTFDRPSKTVSRPPKSSHTPAKTSSCDSNVKRADDGRPCKRRKRVMTSHRTSEIVAATRMLPNGGHLIPCAGGGGVYPEACKNYKSIVDNYPQYKTITCPYRKVDTKKRPITKVFDEQRATDLWDPVINAPNGCSPDEYPPAVMAPVNDGYDILRDMIVPADREVYRLLSAKPPAVDGQMVRYLDAVDNREAGKIFNKCGQPPAASVVHTTTTIVDPDAKVPVEWHLTKIALSRLVWELDFAGLPDNSNDYGVADNICVPTINGKKHPGYALLNSDKWFERPGNEEEADLRDTWPNGPARKRWVEPAGLVLEGANSTRVATPEEVRNHLRLDECADDSCSREIEKLKYVARDFRDKARKAANSPAEAPAPEPTAVSEHNGIQALPPSQPGRYFDSNIPVHTGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYN7</accession>
    <name>E3QYN7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Vacuolar H+/Ca2+ exchanger</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11119</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697405">
        <property type="protein sequence ID" value="EFQ35975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099995.1">
        <property type="nucleotide sequence ID" value="XM_008101804.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYN7"/>
    <dbReference type="GeneID" id="24416484"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11119"/>
    <dbReference type="eggNOG" id="ENOG502SQZ7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027731_0_0_1"/>
    <dbReference type="OrthoDB" id="5314201at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="506"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="351"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="380"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="526" mass="58639" checksum="0DFE4762B4242BA8" modified="2011-01-11" version="1">MDVSSLENTIRVYGIPIDRHTLQAALDDPEHGTAFTEWARLHLGPDNLLSRDELVLYSSLDKSGQIDKLVASQDLASVQAFSEREIQTAIDELNRSTAAIVKQTETLKQQQDALAKLVKSSAKVEEARSDLVFQRSQKHNSERKKTMTSVEELSQSLEYKTSDLEQQSQVASKDLQKTLDSLLHSDDKLLLSLRKLGLELETEDPEDRENIEKLREICMRLIKYTVETVRTKLDRLYLEALSSAHHNGVASHPSDDVKTSQEELESLYAEILPVAQMSVEQQHLEPALKSLSSQNGQSLHRSAAAVVYIDECLDYLLDHIERLSSRIEAFQSHQIATTSLLTTARAELSAPVSTPKTKTPAQDLASPIRRRNTGPGSPTRNRFNSNRGRRSSGFNEPPLEALLRSLAISFPEDATDGARQTAILSATLAEKQAKARDVARNTQESLESAAASQLADARLAVQLLRDSLLAESPFGDVRLVDEGIEASIAVLGQEIERVKERIERVDAGKARQRSERKREILERWGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYV9</accession>
    <name>E3QYV9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MSC1 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11191</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697407">
        <property type="protein sequence ID" value="EFQ36047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100067.1">
        <property type="nucleotide sequence ID" value="XM_008101876.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYV9"/>
    <dbReference type="STRING" id="645133.E3QYV9"/>
    <dbReference type="GeneID" id="24416556"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11191"/>
    <dbReference type="eggNOG" id="ENOG502RNIV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022672_1_0_1"/>
    <dbReference type="OrthoDB" id="2527403at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018803">
        <property type="entry name" value="Ish1/Msc1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10281">
        <property type="entry name" value="Ish1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178996" description="MSC1 protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="546" mass="59777" checksum="EEEC70FD39E66CCB" modified="2011-01-11" version="1">MRFLPTVLTALAAQGVVASSWFSKAAYNKWHETELERWLSDHDIPYPTPADRKDLETLIESNWNNYVVTPYNSWDTDRLQNYLKAKGLQTEGAAKANKESLVTQVQNAWYESGDQAQNAYLNVKDWILDSWTDSQLKAFADKHGIPVPQPRNRDSLLQKARASYETIAQKAGETAAYPGNWLYETWSESDLKEWLDTHGFPAPQVTSRDKLIASVRRNSRLASLKAQEQAASASASAQQAYATLTDMVIDAWSDSQLKEFADKNGIPVPQGTKSNELKALIRKHRADFLQNNVSGAAASAFGAATSNVGSAASKATDAASNAVSDAFNSAVDAWSESRLKAYLDARGVPVPQGSKTDELRALVRKHQHKAASGWSAWTYDDISTDNLRKYLASSSDATVKKVAEKKDASRDELVSAAQSAYSSASSAGGGSYASVTSYLSQATDSAKSSLFDTWSESELKSYLESYGVKVPQGSTLDELRAYARKQYTYFKYGTSTPSETLYAKIAENAKGTWNWVANQVGLGAEAAEKKAADAKKAAYDSKKQEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZB0</accession>
    <name>E3QZB0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11343</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697414">
        <property type="protein sequence ID" value="EFQ36198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100218.1">
        <property type="nucleotide sequence ID" value="XM_008102027.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZB0"/>
    <dbReference type="GeneID" id="24416707"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11343"/>
    <dbReference type="eggNOG" id="ENOG502T69W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_849946_0_0_1"/>
    <dbReference type="OrthoDB" id="4851657at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="327" mass="36122" checksum="709C4126CBB03DC3" modified="2011-01-11" version="1">MTPTRQTIESRDETLIGVKRRGVSVCVTAETDTVSTKTIASNSLDTTNDLGKDTVATIERILSHNQETIQQNELEENHASLFLEIQKPPTPVEAERGIVYVEEHELGNGLFKIGWREDTARVSITPSDSCNKLNSKVIYETPGGPFLAASKVKQLSLTALHPQILVVMERHHGGRGYEEWISAPLEKVLQTIKTLENFVKLPAYESKDGQNWELSFTANKIIRGMDIFLLENLEGSMNSTEGDSAGNTVAGFATGLSQETVTCVAETAASPTLLDTEEELEGRRTLTTPDPKSFSKESNSEKMWEHKSNEVRQLVLLPICSGVCCVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZI3</accession>
    <name>E3QZI3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">T6SS Phospholipase effector Tle1-like catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_11416</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697416">
        <property type="protein sequence ID" value="EFQ36271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100291.1">
        <property type="nucleotide sequence ID" value="XM_008102100.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZI3"/>
    <dbReference type="STRING" id="645133.E3QZI3"/>
    <dbReference type="GeneID" id="24416780"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11416"/>
    <dbReference type="eggNOG" id="ENOG502QPR9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005049_0_1_1"/>
    <dbReference type="OrthoDB" id="3162439at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018712">
        <property type="entry name" value="Tle1-like_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840:SF2">
        <property type="entry name" value="TLE1 PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09994">
        <property type="entry name" value="T6SS_Tle1-like_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T6SS Phospholipase effector Tle1-like catalytic" evidence="2">
        <location>
            <begin position="25"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="285"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="455"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ36271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="630" mass="71409" checksum="BDF2C7306E077AF3" modified="2011-01-11" version="1">MSATEPGDQTGNGAYRGSQQRGPRRKLILCFDGTGNKFRGDDSDSNILKIFRMLDSSADDQSGIGTYVVSENLTHNGIRAKCKSWYQMAKDSVVGSSFDQHVVGGYRFLMRYYSPGDDIYMFGFSRGAYVARFLAEMLDFVGLLLHGNEEMVAFAWNAFSQWQCRRTNSTAKGKEETEQMYQFLRGFRETFSRPIRRIRFLGIFDSVNSVARFETAWMQRSKFPYTARSSAKVVRHAVSIDERRAKFRQDLIYQEPKKCHRKNTAKRMMEHQPFNEKLQEFQEKYRPGRRSTLAPDDAVAAEDRGRRRHHQSQEDNADHPAPFRSRSRSRSRATDGSRCAHTDHDGSSIHSKPPMEDLTYDSDDDEADQNVEEVWFAGGHGDIGGGWDAVAGRKNASHIPLVWMVREAMRAGLSFDVQQLEYLGCVETVTGPNPQPTPPSLMPQDVPGVPEIHVDAPSPPVGFPSESPDGSTTEKTDENPDPLAHTCTATPFAEMMRTAHEAEIHDSLDFACGMHPVSVFMWRAMEYLPFRRLDLRPDGSWKPIRWPLPRGEVRDIPDKVRVHGSVIRRMKRDEKYRPGNLIVGGGGRGCRVAPKEYGMGEWVCVKGEGDLIDEVWVRKPRDEGNEESHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZQ9</accession>
    <name>E3QZQ9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11492</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697419">
        <property type="protein sequence ID" value="EFQ36347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100367.1">
        <property type="nucleotide sequence ID" value="XM_008102176.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZQ9"/>
    <dbReference type="GeneID" id="24416856"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11492"/>
    <dbReference type="eggNOG" id="ENOG502T4Z0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2145683_0_0_1"/>
    <dbReference type="OrthoDB" id="4850317at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="112" mass="11599" checksum="780B180EA539EDE1" modified="2011-01-11" version="1">MAKQSSKQTTTFNSENSSSKTSGGQSAASSTVPVDRSWQYRPLGRGQAVTGGSGSYCVGRWLTEPSWQEPFNTIAEVPAAGSEAGQGVGGQGSGASATCATSRTQKQQQQQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZY0</accession>
    <name>E3QZY0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_11546</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the major facilitator superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697423">
        <property type="protein sequence ID" value="EFQ36418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100438.1">
        <property type="nucleotide sequence ID" value="XM_008102247.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZY0"/>
    <dbReference type="STRING" id="645133.E3QZY0"/>
    <dbReference type="GeneID" id="24416910"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11546"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_11_3_1"/>
    <dbReference type="OrthoDB" id="3936150at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015606">
        <property type="term" value="F:spermidine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000297">
        <property type="term" value="F:spermine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000082">
        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF38">
        <property type="entry name" value="POLYAMINE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="199"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="297"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="335"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="378"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="403"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="448"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="472"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="74"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="9"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ36418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="509" mass="55962" checksum="FD766A9862B7EDAA" modified="2011-01-11" version="1">MASQLPVRSSEETKTASSSEDHLRHDPEKQHVTESSKTQPGDEASKHVQNEANWNWDTDPYNPLNWPARQKFTQMVMISLAALTSSLGTSIISPAHTQLMEEFGVTATQAIVPLSMYVFALGLGPVVGGPLSETVGRHPVYLFSLPLGALFTLGVGFCHSFAGVCILRFLAGFCLSPSLAIGSGTINETYQPSERALPTTAFILMPFLGPGLGPVIGAFVVNRKGWRWTQWTMLFFIATAMVSTILSKETYHTVLQRRRAAQLGLPVEPLPVARERVHKFATSALARPVRMMFTEPIVSFICLYVACEFATLFSFFAALPYVFRTVYGFGIEQQGLIFLSIAVGCVLGSLTIMLCNAVIYLPQTKKHPPQRTPPEYRLYPAMVGSIGLPLGLFWFGWTAREDISWASPVVAIMPFAWGNICVFVSTMQYLLDVYKGTNVASAASANSLARYVLAGAFPLFVVQMYTNLGIGWASSLLGFIALALMPVPWAFFKFGRAIRQRSTFDTVTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3R035</accession>
    <name>E3R035_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_11618</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697426">
        <property type="protein sequence ID" value="EFQ36473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100493.1">
        <property type="nucleotide sequence ID" value="XM_008102302.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R035"/>
    <dbReference type="GeneID" id="24416982"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11618"/>
    <dbReference type="eggNOG" id="ENOG502T522">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_994004_0_0_1"/>
    <dbReference type="OrthoDB" id="4851359at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ36473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="280" mass="32130" checksum="2C28F69123CE2FA3" modified="2011-01-11" version="1">MSNRQCCFGNNLVPNYLRWLYNDKDLPITFRKEAPNVWDCGVYALVFASHVADGKPLPMTIDGARERVYLRHCMLVSHDRALASTESNGECRTLRAQAEAAKHLNRRMRNFDELLQDGSDDLLKWMARKEVFREGQAALADAIATLHNMHLMTVESATRAETQAANAKGLKDFHKALKTIMCMNNLAWRDQHDCSLFKLSDSTIRHLNIVQDSSRLLDKDLTQLLETDNRRDLADETRLGYRECSALIIVLNYAVRKFRENATDMKRRQGNAHKELQGHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0A1</accession>
    <name>E3R0A1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ubiquitin-like protease family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_11674</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C48 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697436">
        <property type="protein sequence ID" value="EFQ36539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100559.1">
        <property type="nucleotide sequence ID" value="XM_008102368.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0A1"/>
    <dbReference type="STRING" id="645133.E3R0A1"/>
    <dbReference type="GeneID" id="24417038"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11674"/>
    <dbReference type="eggNOG" id="ENOG502T523">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_375052_0_0_1"/>
    <dbReference type="OrthoDB" id="1939479at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019783">
        <property type="term" value="F:ubiquitin-like protein peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.395.10">
        <property type="entry name" value="Adenoviral Proteinase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003653">
        <property type="entry name" value="Peptidase_C48_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02902">
        <property type="entry name" value="Peptidase_C48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50600">
        <property type="entry name" value="ULP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like protease family profile" evidence="5">
        <location>
            <begin position="352"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="142"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="185"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="265"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="142"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="219"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="280"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ36539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="740" mass="81965" checksum="0165ABCF5C1B8321" modified="2011-01-11" version="1">MSSGPLENALDIVNAFKFDIDNVWTTLLEQWNHLQEAFESISPPPCQPFQLWAYDKVDPKVLTTVLSELFQHHLVKQRNLRYRLAAIAHRFNLEPVIVCFFLGIEVALNLQCLTALKTLQSNKPEVTLTDIATRVHHLQTDITDSSDSASRTNKSEATAGPNLRGRPLEPARKRFRDAIQFYDPTAWPVRQPKGGPRPKKSTSSTQPFPPSSPVSSIHCSDEMETKGGKLTREASEPIAPPHTIQVDLCPKTQTSRQTTLSLIQECSEEEVSETSAFEQGRGDKGNDHSVALEDTSDQFCSFHVSQDFNDDDEFDDDNKFEHTLPPATYPVFHNHQDEEDSLAQDITQTPSIDVGTQSKSLMANTRRPNLEWLISHLDRFDSGKWFNDDIINTLLRRLCSDSVASVETGAPTSAWRGWTKTPQWIEQASRKAAMLIPFNQGGSHWVLYHYASSILHVYDPLGHDVSRDNITTQEVAPFVSRVYGLALPPRVMSLKGPIQPNTWDCGVYLIAAASILAEGNTLPDKFDGDVLRQRYRNMYLTSPFSTPAESIWNSHAASEGTTTGAIAFFKFKSSVLLNAATSSYADGDFRSSRIRDFLANETLHFGAGASLSGLKALHRQHEAHLRAALEKTAALTIISEKETQVLNLKAIHRLAQGLAARVGDFNAAQQVPPGSNALMSAAKATEASSQTLMALIEAETNPDATLQTLHAEAQGIEAEIAYSYRLCVVYILLLRKAATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3R107</accession>
    <name>E3R107_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11941</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697543">
        <property type="protein sequence ID" value="EFQ36795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100815.1">
        <property type="nucleotide sequence ID" value="XM_008102624.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R107"/>
    <dbReference type="GeneID" id="24417304"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11941"/>
    <dbReference type="eggNOG" id="ENOG502T5IQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_754417_0_0_1"/>
    <dbReference type="OrthoDB" id="4846206at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13270">
        <property type="entry name" value="PROTEIN C20ORF116-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13270:SF14">
        <property type="entry name" value="SEX DETERMINATION AND DOSAGE COMPENSATION PROTEIN SDC-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="282"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="245"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="435" mass="47754" checksum="59D32CC8A836602E" modified="2011-01-11" version="1">MGSDQGQHHQQQHQQHQQQQQQQQQQQQQQQQQHQQQQQQQQQQQPGPFAGIRSLTAVQSYQFYQHPTDANLGRWATSAAPTITGHQAAALIHHTKNHAAGITAHLADQGVTTTPRQNLAQSHMTYLRNHWPNGQWYPDTCRPSTDPPSLDVLTPFKSMTQHWLAHSQGRSLLDLWAQSPQRGIIWQIVNETRSTGLTKRVAQESLRRVKTTFPAAAAPRPKPAAPAPTPAPAPVSEPEPEAPRADPLLPPLAADDEFAPPALGQAERPSLRLTTIALPPLDSAPEFGYSRTPSPPPMPESDDDESDVSVDGVLGDLFGQPGIPLAPVSKKYKRVRELGLAAAKKKKDTAETSARRRRYAEERAAAAAAEAAEIGEDGLGSEKIQDIAEVLADAASKAVSRAAKRHYGHLLPPGRRAVMTKRAKQKTKEMVTDYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3R143</accession>
    <name>E3R143_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cholera enterotoxin subunit A2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_11978</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697602">
        <property type="protein sequence ID" value="EFQ36831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100851.1">
        <property type="nucleotide sequence ID" value="XM_008102660.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R143"/>
    <dbReference type="STRING" id="645133.E3R143"/>
    <dbReference type="GeneID" id="24417341"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11978"/>
    <dbReference type="eggNOG" id="ENOG502RFNY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091751_1_0_1"/>
    <dbReference type="OrthoDB" id="4927890at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090729">
        <property type="term" value="F:toxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.210.10">
        <property type="entry name" value="Heat-Labile Enterotoxin, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001144">
        <property type="entry name" value="Enterotoxin_A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01375">
        <property type="entry name" value="Enterotoxin_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00771">
        <property type="entry name" value="ENTEROTOXINA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56399">
        <property type="entry name" value="ADP-ribosylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0800">Toxin</keyword>
    <keyword evidence="3" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003181079" evidence="5">
        <location>
            <begin position="24"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ36831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="229" mass="25713" checksum="87EE19792A5F1917" modified="2011-01-11" version="1" fragment="single">MAYLQKLLLFFYLASFWFSSGECAPFRRTGPKFVYRGAGRSPQEIKAAGGFLPKGLTTVGVVAPDISLFSHVDVPQEVDENGNSIGLGSTADNDGYVSLTKSFFLALGHAFYSRDQKTTYVYKIKSTPNMIDVAKTLREYNLYEEEDEFSALGGVKWDQIVAWYKVDGHSLRTYSWLWQIKNPDYNARKYSGFRPGGAQYGLAGFPADHEAWNKEPWSKFKPCSGETST</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3R144</accession>
    <name>E3R144_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CRIB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_11976</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697603">
        <property type="protein sequence ID" value="EFQ36832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100852.1">
        <property type="nucleotide sequence ID" value="XM_008102661.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R144"/>
    <dbReference type="STRING" id="645133.E3R144"/>
    <dbReference type="GeneID" id="24417339"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11976"/>
    <dbReference type="HOGENOM" id="CLU_1547435_0_0_1"/>
    <dbReference type="OrthoDB" id="5237293at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ36832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="173" mass="18809" checksum="C1B9206C84DAB677" modified="2011-01-11" version="1">MRSQDHLESVKLFGKNIFGRRKTSRENGLGDGAATGRQLQISGPYNFRHLNHTKHEHPLNLPRSSYVDLITEFSAICADQRPTTAGHLGGIDVEDTCLAKLSWPLRSSIHEEPVEPTLPVSSAPSPRSSSLVTTPFIISSDSVVTSDSTLEHPQTSSGVKIPSCFSLTMEAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q1X2</accession>
    <name>E3Q1X2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MYB DNA-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_00217</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089093.1">
        <property type="nucleotide sequence ID" value="XM_008090902.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q1X2"/>
    <dbReference type="STRING" id="645133.E3Q1X2"/>
    <dbReference type="GeneID" id="24405582"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00217"/>
    <dbReference type="eggNOG" id="ENOG502RZP2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039317_2_0_1"/>
    <dbReference type="OrthoDB" id="2143914at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:snRNA-activating protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001006">
        <property type="term" value="F:RNA polymerase III type 3 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042795">
        <property type="term" value="P:snRNA transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042796">
        <property type="term" value="P:snRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051575">
        <property type="entry name" value="Myb-like_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621:SF1">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Myb-like" evidence="6">
        <location>
            <begin position="209"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="114"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="62"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ25073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="265" mass="29503" checksum="807434F386ED2452" modified="2011-01-11" version="1">MQQQQQQQQQQQQQQQQQQHPHHPHHPHQVLMDSGHHMGHARHLGPPHYGAPGPVVAPLYPSMSTPTQTHTPHGTKRSRPDELDLAVPGIDLDHTDLESMQQTPLGTAYAQTVQPPTHHHHRLPDTGPPSKMMRRDGDGGDRGGAPSVVGQAGMPSPAPRPRGPKLKFTPEDDQLLIDLKENKSLTWKQIADFFPGRSSGTLQVRYCTKLKAKTTQWTDETDQKLRTALQDYENEKWRIVANKVGTGFTPAACRERVAELTGGPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2K9</accession>
    <name>E3Q2K9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_00454</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089330.1">
        <property type="nucleotide sequence ID" value="XM_008091139.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2K9"/>
    <dbReference type="STRING" id="645133.E3Q2K9"/>
    <dbReference type="GeneID" id="24405819"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00454"/>
    <dbReference type="eggNOG" id="KOG0158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_11_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11058">
        <property type="entry name" value="CYP60B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF230">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="452"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ25310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="506" mass="57288" checksum="2F72632A41D90DB7" modified="2011-01-11" version="1">MAAFDFLWPITGLAPSTMAVSIPLFLGAALVVIFILSLVYNLYFHPLRRYPGPRSWGATRLMYSWELVHGRAHKSVLALHKQYGDIVRIAPDELSVCSPAMWREVWGRRKTELGEIPKDDIHYAEALTSILGCPKKQHTRFRRILAPGFTGTAVAEQSPFIKKHVDNFFRVLHSHVAARGQQAIDISEWFDFAMADIASDLSFGDSFDCLNTGKYHPWTQLFNEAHTGHAYAKATQRFPLVTPLFKLVAKNSPLQKRWDANVNSTRRLVDRRLLEADRPDFVRALASHGNSDEKEPLTRDEIQWNAQILMSAAYDTTAVGLTTATYLLAKHPEWAQKVADEMRAAFASDNDIVGLATLELKVLNAAIDEALRLLPPAGSAMPRVVPAPGENVFGEFMPGGTILTMWMWSTYRNPANFKNPDEFHPERWLGDKEYDGDRKDVFMPFSFGMRACIGRQLARAELGILIGRLLWNFHLEVDPSEREDWIDQPNLLLWQKGTLMVNLTSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q359</accession>
    <name>E3Q359_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DUF788 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_00182</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM208 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089058.1">
        <property type="nucleotide sequence ID" value="XM_008090867.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q359"/>
    <dbReference type="STRING" id="645133.E3Q359"/>
    <dbReference type="GeneID" id="24405547"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00182"/>
    <dbReference type="eggNOG" id="ENOG502S72U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094308_1_0_1"/>
    <dbReference type="OrthoDB" id="10012212at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006624">
        <property type="term" value="P:vacuolar protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008506">
        <property type="entry name" value="SND2/TMEM208"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13505">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13505:SF7">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05620">
        <property type="entry name" value="TMEM208_SND2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="81"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ25038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="160" mass="17410" checksum="2B628D4BE592F6B0" modified="2011-01-11" version="1">MAQKAKKDRAKSNAAALNNLHTGSAVVNLGFLLFYFFTKSRSIFWFFLLSAPALVCEFILESTGRPKYDTAGGLKTSGEDLAASGLTEYMFDVIWVTWASVVLVILFGNWAWILWLSVPAYGAYAGVGLLGAGKRMAQMGGAANNQEPAPPVNRRQRRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3K1</accession>
    <name>E3Q3K1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_00747</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089623.1">
        <property type="nucleotide sequence ID" value="XM_008091432.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3K1"/>
    <dbReference type="STRING" id="645133.E3Q3K1"/>
    <dbReference type="GeneID" id="24406112"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00747"/>
    <dbReference type="eggNOG" id="KOG0583">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003954_1_0_1"/>
    <dbReference type="OrthoDB" id="193931at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045033">
        <property type="term" value="P:peroxisome inheritance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000011">
        <property type="term" value="P:vacuole inheritance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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        <property type="entry name" value="STKc_Kin4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000397">
        <property type="entry name" value="Serine/threonine-protein kinase KIN4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
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    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034674">
        <property type="entry name" value="STK_Kin4/ppk1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF110">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="215"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="526"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="39"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="63"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="106"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="125"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="526"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="616"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="641"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="657"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="823"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="860"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="965"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1004"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1081"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ25603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1098" mass="119986" checksum="4AF5DFCC51889CC5" modified="2011-01-11" version="1">MTSRAAPASSVAVAPSSLDCHQSSPEQRKNMPPIAPPRTSSTNYSSAAATATTKRRDHAADKASSSPRRGQADATNGNADYTYSDDGSASRSRRSHQQMAPDSPHRSTGNRPGSQPTVIPVRSHAPSQTTASPKQPSREASEVLNRMVISQPEVDIAREKERLAEAQPTHIGSLQDDAAPPPVVAMTEHDDGRRGVRSRHEHSGKREKVVRFGDYILGNTIGEGEFGKVKLGWKNDGGVQVAIKLIKRDSVGNNPSRLAKIYREIAILRGISHPNIVRLHEMVETERHIGIILEYASGGELFDYILNHRYLKDNAARRLFAQLVSGVGYLHKKGIVHRDLKLENLLLDRNRNIIITDFGFANTFDAEEELSEEEELNLGDREFVKKLGLDRVKTNGSRKGDLMQTSCGSPCYAAPELVVSDSLYTGRKVDVWSCGVILYAMLAGYLPFDDDPANPEGDNINLLYKYIVNTPLTFPEYVTPHARDLLRRILVPNPRKRADLFEVARHSWLNEYAHVVEFITSSTTTPNEIQNTTVPSDDFEEEPGIGRSASVREASKTKASTPTSVGGLASKHAKIDTDAEAAAIAKQHKDNKRRTVQVEYVAPTTQTQRGEAAPSGSKSRARSNSQGPVEVADGQALQDKPLPRDPPVSRDSYRVASRQNTRPPSSHRNTATAPSRPTRETRATSDNAFVSSTSSAPATGRPQTGNSMASGSMGLGAGNRTSYSQPIPPAVAGTNAHGRIQQPSSQEPQAMGRPSVSVPSKFAKVAGFAPEQQAAQSQSQSQAQNQTPPQPSDGRAHGHKRSNTIGSLLGRNGSIFGGKNRSKRPESQMADKSRKYPPVSMPNNMPAEGQPRPSIDSRTSRHSFSRSFGKKRSGSIAGSQTSHEKPNRRFSLIPQSFSLRAIGLGRDYDRPPSEPQSQPDLPIQDPPEVDEHGRYVDRQGQSRGYDGGHDQGGYRQPPGSNSAPQLQHQDWQNQQQDYQQQQEQQHMGPIGQPSSVPGYMQQGAVLNTGSESSFENAYQQRRQSSAAYHGGGVSESEGYDRQQQSNSPRGHGRSSLLQKNNKRFTDADYTGHQGSSGAAKRVMDFFRRRGKARGGDER</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3Z3</accession>
    <name>E3Q3Z3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00889</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089765.1">
        <property type="nucleotide sequence ID" value="XM_008091574.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3Z3"/>
    <dbReference type="STRING" id="645133.E3Q3Z3"/>
    <dbReference type="GeneID" id="24406254"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00889"/>
    <dbReference type="eggNOG" id="ENOG502S9SQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093552_0_0_1"/>
    <dbReference type="OrthoDB" id="5422613at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38167">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38167:SF1">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="241"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="250" mass="28215" checksum="3A7B3CA6DA26D502" modified="2011-01-11" version="1">MDYASSSSPVDSPTPSFFTSDLDGLAQAPSPVARAILVALCDDRRVRAQALRQLGRLLRFEADVRGHDPVKSPGSVTSPSSSKKRKVTGEPKICVQCDCIFTDDENSFGACWYHTGQLELWDETQIPTLWDEISSDELDTESNRAEYPAAFRWCCCERLGDRTGCVRGHHESNPDKSKKGRGNELSDLDLEDDPLELDASDDLQPPLQQHYTIANPQETTPRKLPMHHQQQQEEQHHRLLHQPQQQHPLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q404</accession>
    <name>E3Q404_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histone deacetylase</fullName>
            <ecNumber evidence="2">3.5.1.98</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_00900</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the histone deacetylase family. HD Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.98" evidence="2"/>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089776.1">
        <property type="nucleotide sequence ID" value="XM_008091585.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q404"/>
    <dbReference type="STRING" id="645133.E3Q404"/>
    <dbReference type="GeneID" id="24406265"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00900"/>
    <dbReference type="eggNOG" id="KOG1342">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007727_0_0_1"/>
    <dbReference type="OrthoDB" id="1918432at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033698">
        <property type="term" value="C:Rpd3L complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070210">
        <property type="term" value="C:Rpd3L-Expanded complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032221">
        <property type="term" value="C:Rpd3S complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141221">
        <property type="term" value="F:histone deacetylase activity, hydrolytic mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031507">
        <property type="term" value="P:heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10004">
        <property type="entry name" value="RPD3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.800.20:FF:000001">
        <property type="entry name" value="Histone deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003084">
        <property type="entry name" value="HDAC_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="HDACs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625:SF10">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01271">
        <property type="entry name" value="HISDACETLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Histone deacetylase" evidence="11">
        <location>
            <begin position="36"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="381"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="401"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="417"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="435"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="460"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="500"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="551"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="589"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="612"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="643"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="667"/>
            <end position="679"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ25756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="679" mass="75441" checksum="A9C1DAE881825154" modified="2011-01-11" version="1">MSPLGSVALANGSATPKKVAYFYDSDIGNYAYVTGHPMKPHRIRLAHSLIMHYDLFKNMEIYRAKPATRGEMTQFHTDEYIDFLQKVTPDNMDAYQKEQGKYNVGDDCPVFDGLFEFCGISAGGSMEGAARLNRQKCDIAVNWAGGLHHAKKSEASGFCYVNDIVLGILELLRFKKRVLYIDIDVHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGELRDIGIGTGKHYAVNFPLRDGIDDTSYKSIFEPVIEHVMKFYQPEAVVLQCGGDSLSGDRLGCFNLSMEGHANCVAYVKSFGLPTLVLGGGGYTMRNVARTWAFETGVLVGKHLPKTLPYNEYYEYYAPDFELNVRPSNMENSNSFEYLEKIKAAVIDNLRHTQPAPSVQMQDVPRQPFGGMTDEEEAELNDMDEDEHPDERMTQRRWEQRTRNEAEFEDSDDEDMDEANGMTRPRNAKKRTFGDYRQTDRDADSGAPSPVNGAPEGEEAPNAEPIVDADITLEKTVDTEDVPEKTVPEKEAAPEAPKEHVVDEDGDVGMGDSVDAEEATTTIKKEEVEAEPTKVAEKDEKEDKPASRKPSTEPAAEPLSAETTETVEAAEPAAEVAKAVDPQPAKEAEVAEAKETKDEATHEEPPVAAEEPAPEQEKVVADEKPEEKAPEPEEDKMDVDEKPADDSAKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4E3</accession>
    <name>E3Q4E3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="7">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_00599</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="7"/>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089475.1">
        <property type="nucleotide sequence ID" value="XM_008091284.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4E3"/>
    <dbReference type="STRING" id="645133.E3Q4E3"/>
    <dbReference type="GeneID" id="24405964"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00599"/>
    <dbReference type="eggNOG" id="KOG2429">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003818_2_0_1"/>
    <dbReference type="OrthoDB" id="8118055at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044322">
        <property type="term" value="C:endoplasmic reticulum quality control compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904380">
        <property type="term" value="P:endoplasmic reticulum mannose trimming"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044674">
        <property type="entry name" value="EDEM1/2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45679:SF5">
        <property type="entry name" value="ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45679">
        <property type="entry name" value="ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180078" description="alpha-1,2-Mannosidase" evidence="8">
        <location>
            <begin position="21"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="336"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="467"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="488"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="574"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ25455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1067" mass="118641" checksum="645A9D1C912BB804" modified="2011-01-11" version="1">MLSQLLVLAHLCLLWPLAVSAISPARLAELRNATTQVFHHGWDNYMRIAFPEDELRPISCTPLTRDPANPANYDLNDVLGNYSLTLIDSLSTLAILAGTPSDHNTAVWALQEFQQSVSAFVEYYGDGRRGPSGQGRRARGFDLDSKVQVFETVIRGVGGLLSAHLFAVGELPIPGYNPGQVSNQDEDEDPLELRPISWPNGFKYDGQLLRLALDLAERLLPAFYTKTGLPYPRVNLRHGIPFYVNSPLHKVSRDDPDSPRNTNEKTDTCSAGAGSLVLEFTVLSRLTGDPRFEQLAKRAFWAVWKAKSEIGLIGNAIDPEKGEWVSFDSGIGAGVDSFFEYALKSHILLSGHELPNVTISEPPTDRQWLDPNTLHDTPLTPEENSAGAFLEAWHHAHAAIKRHLYNDAHHPYYMTGHRTRGYAFTSWIDSLAAFYPGLLAMAGEVEEAEEANLLYTALWTRYGALPERWSVRDRQVDSGIGWWPGRPEFIESTYYLYRATNDPWYVHVGEMVLSDIKRLCYTKCGWSGLQNVDTGEKADRMQSFFLGETTKYLYLLFDPDHPLNKLDAAYVFTTEAHPLIIPRRRTKPKRKQKSNRQARSVDVYYDENFTNTCPAPTKQVPLTGSVLAARPDVFHAASFVNLHTISNPRSGVELVPAGKGSNGSISRYKANHTFFPWTLPRSLIPDNGTCAALPFKPTLIIEFPSTVQQGSVGSAFNNLFANTAAFKTPVGVRISALSGLKVYFVQEDTFDSAYDHTWRVTQVNHLPLGRDEPVHIDADLLKGISDPLFNRVRYNGFIELIMMHGEPEEHNASAPVPAEGLEVDIGDFDNQVQLTEEARPELADDQAADKGMNTAYRSMLKSMIRAVTSVFDPANTPAPLPAGTQAKFHVESYMGALAVGKGAVPLPDVPDASIPADDAAPTLQWQTVYRAGFGCDGRLPDEAPRHHQVIVMRRGGCSFSEKIANIPSYTPSARSLQLVIIVDEDELENDYVFSAPDMWEYEMIKPHLDVEQITPAGLRRPHPIAMVMIRGGGPEAYEKFGNALGVGVRRKYFIETQGRRVDNIIVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4F7</accession>
    <name>E3Q4F7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fibronectin type III domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_00613</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089489.1">
        <property type="nucleotide sequence ID" value="XM_008091298.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4F7"/>
    <dbReference type="STRING" id="645133.E3Q4F7"/>
    <dbReference type="GeneID" id="24405978"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00613"/>
    <dbReference type="eggNOG" id="ENOG502R2RI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005801_0_0_1"/>
    <dbReference type="OrthoDB" id="5572782at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178199" evidence="3">
        <location>
            <begin position="18"/>
            <end position="1148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="33"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="4">
        <location>
            <begin position="111"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="200"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="402"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="537"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="621"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="714"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="794"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="874"/>
            <end position="1148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="362"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="438"/>
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        </location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="544"/>
            <end position="557"/>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="649"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="686"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="753"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="894"/>
            <end position="908"/>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="925"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1032"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1056"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1089"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1125"/>
            <end position="1148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ25469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1148" mass="127567" checksum="7CBC52C2E2C14F48" modified="2011-01-11" version="1">MLWTLFMKILLISSLVAWWLKRPNSRFQKFVLFAATLATFWVVAPLYASLCLAWSVHYTREGIRYWSLDELLVRHASMLVTLAAVIWLLHRAWQTLWKPTTDLISILGVDVPEAPDVSLAGIRPDAATLNWTRPTHNRPVQKFLIQVNGVNVGESRQEETAITVTGLRPNHCYNIRVIAVGPNNFQAGSQVIRLRTYRSDGRPELGNSRLPDSFQDQDPKSGQFPCLEDNGSRSQVPTIEAAPSLEGGSAAVRDGPSGQRRNTVNRRHSPSIASQEQPSIKDLGGDQPEASLKDLADALERTRKEIDETASLHASEESEFKQLEERLKKEKEEKKKMQKEKDDNTAQLRQKVKATYEQMRQATKDKARKENLLKEKQEKRKKIIDNIDKWTAEIENMRKTRKGFAAEKESLEQDRDLKIKHLDEDNSALQDEYSQLETEYKEKKEQLKELEDARRKLPGGEEDDTWREDDRKMKRDFEMKRRELQSQLIMENRKSQQLEGHIHVLHAQVYAQNQQSLQFYNQANSSGVDFDQNLSAQVKRRSRTGNSLSNAAMSSPTGPFPASDSFEPPISFSSRTGFSHFLEISGADNFGADQFSDADFRALTSNAPLSPTAAALLPSGILGDDDSASPDSFSRRSPFLPDDEYDAHSPQSSKRSNSAHSSPLGPSHKIAFPQLAPDNGDHASFNDVTSSPSGQPSPAAHRFTNLLSSFQRGKGAKAVDDGGPILGSLKHGQSQSFPRQADDPEGTIRRRTSFSSLGRNRNSAGPETMESSASHLGRSMFSSARRLMLWNGSFVDRDPSSPRPTSMTSADLPRPSTDSGSIWNHPGERNRLWSPDGPWPSRTPSRRPSLHGSPAALQTTLASADDEILDHEALNDPQVSPSQVGVIGSRPPASKQNSDSKSLLSQRLNPAAPTFSIGGIGGLFRSKDKESDSGKEKDKTKSKDKARDKAKDKEAKEKGKTRELSTPSLDPPQGYDTSPTDSRKSRDAFSVHTQTSVTESRESLTLDRAVSSTLSDSNAKDQENAYRKLFRKGSSSKFSLSSRLSKDSGLFKKGPGSTTNSDKNLSADRSSFGDIDDYGEEGLFGRSYESFTSSPSLGPSKSKETKESRMTNWSNKFSMKKKGKDNKESVELHRATHEAEAEGDKNDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4U0</accession>
    <name>E3Q4U0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">carnosine N-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_01249</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carnosine N-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.22" evidence="2"/>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ26105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090125.1">
        <property type="nucleotide sequence ID" value="XM_008091934.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4U0"/>
    <dbReference type="STRING" id="645133.E3Q4U0"/>
    <dbReference type="GeneID" id="24406614"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01249"/>
    <dbReference type="eggNOG" id="KOG2798">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030612_1_2_1"/>
    <dbReference type="OrthoDB" id="978at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030735">
        <property type="term" value="F:carnosine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012901">
        <property type="entry name" value="CARME"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12303">
        <property type="entry name" value="CARNOSINE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12303:SF6">
        <property type="entry name" value="CARNOSINE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07942">
        <property type="entry name" value="CARME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01296">
        <property type="entry name" value="N2227"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ26105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="411" mass="45895" checksum="1604AD66B8BFC93D" modified="2011-01-11" version="1">MADDEQWSGMENTIEDPEETRVIFCALDSFLQYAKVAHFNVTHLRRQSFYALPQAHWQMLAAPPFNFLDTLERTDEAIEANAELAHAIAHNGLRSFHLVPEGSTEEPRLPDAWVGVAKHNDTDKARSTLRQFYRDWSAEGAEERRVCYDPVLDAVDRERQARPSPTSAPAEPLKVLVPGAGLGRLVFELCRAGHDAEGNEISYHQLLASSYILNCTKTAGQHKIYPWAHSFSNHRTRTNHLRSCAVPDIHPATQLAAAGPSAGSMSMCAADFLCLYADDDHRAAYDAVATVFFLDTAPNLVRYLETILHCLRPGGVLINFGPLLWHFENNAPGNHGRDTDGDGEHDYNNSSGIADPGSFELCDDEVMALVERVGFEVERRETGIEAPYIHDPESMLHTTYRASFWVARKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5X3</accession>
    <name>E3Q5X3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">FMN-dependent dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_01365</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090241.1">
        <property type="nucleotide sequence ID" value="XM_008092050.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5X3"/>
    <dbReference type="STRING" id="645133.E3Q5X3"/>
    <dbReference type="GeneID" id="24406730"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01365"/>
    <dbReference type="eggNOG" id="KOG0538">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020639_0_1_1"/>
    <dbReference type="OrthoDB" id="25826at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03332">
        <property type="entry name" value="LMO_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000132">
        <property type="entry name" value="FMN dependent dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012133">
        <property type="entry name" value="Alpha-hydoxy_acid_DH_FMN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037396">
        <property type="entry name" value="FMN_HAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008259">
        <property type="entry name" value="FMN_hydac_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037350">
        <property type="entry name" value="LMO_FMN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578:SF86">
        <property type="entry name" value="DEPENDENT DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G02720)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578">
        <property type="entry name" value="S -2-HYDROXY-ACID OXIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000138">
        <property type="entry name" value="Al-hdrx_acd_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00557">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51349">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 7" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN hydroxy acid dehydrogenase" evidence="8">
        <location>
            <begin position="10"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="280"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="89"/>
            <end position="91"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="280"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="311"/>
            <end position="315"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="334"/>
            <end position="335"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ26221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="393" mass="42330" checksum="781923769C085FAD" modified="2011-01-11" version="1">MADFGDGDERLPIVTTDPNGLEAQAKKAMDPKPFGYVFGGAGELSTMDANRLAFRQWKIVPRFLRPNNPRDLRTELFGLTYETPVLMAPIGVQGIFHADKETGLAAACAELKVPYTLSTAATSTIEEVAEVCGDHHRWFQLYWPMDDEITASILRRAKANGYKVLVVTLDTVTLAWRPTDLDNAYLPQIAGTGNAVAFSDPVFRRKFAEQNDGDVVEENVIGASRHWLSEAFPGEHHGWKDLALLKKHWDGPIVLKGVLSAEDAKLAVEHGMSGVIVSNHGGRQLDGGVASLEMLPEIVEAVGDKLTVMFDSGIRTGADIVKALALGAKAVFVGRPAIYGLGIAGKEGAKAVIAGLLADLDLTMGLAGFKKISDLTPSILRLVRYGGDVKANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6A5</accession>
    <name>E3Q6A5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pentatricopeptide repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_01497</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Regulates mitochondrial small subunit maturation by controlling 15S rRNA 5'-end processing. Localizes to the 5' precursor of the 15S rRNA in a position that is subsequently occupied by mS47 in the mature yeast mtSSU. Uses structure and sequence-specific RNA recognition, binding to a single-stranded region of the precursor and specifically recognizing bases -6 to -1. The exchange of Ccm1 for mS47 is coupled to the irreversible removal of precursor rRNA that is accompanied by conformational changes of the mitoribosomal proteins uS5m and mS26. These conformational changes signal completion of 5'-end rRNA processing through protection of the mature 5'-end of the 15S rRNA and stabilization of mS47. The removal of the 5' precursor together with the dissociation of Ccm1 may be catalyzed by the 5'-3' exoribonuclease Pet127. Involved in the specific removal of group I introns in mitochondrial encoded transcripts.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Binds to mitochondrial small subunit 15S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCM1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090373.1">
        <property type="nucleotide sequence ID" value="XM_008092182.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6A5"/>
    <dbReference type="STRING" id="645133.E3Q6A5"/>
    <dbReference type="GeneID" id="24406862"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01497"/>
    <dbReference type="eggNOG" id="ENOG502S3E1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014148_1_0_1"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447">
        <property type="entry name" value="OS03G0856100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447:SF23">
        <property type="entry name" value="PENTACOTRIPEPTIDE-REPEAT REGION OF PRORP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="514"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ26353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="735" mass="83498" checksum="F7AF041AD5F21BF9" modified="2011-01-11" version="1">MSGVAEMEEELKANLTSNMRRVLFRLQEEGSLGAFGINDVESIAKDFEGKLGGANNPEEMMAKLDDYIKDLERQLDAAGFDVSQFDDSNPVATMDVIEATAREDPSKRKKHPPIPQIPENVWSFNQRKRITRLNTLLSRTTKEIRRGEGVHAKNIQPVWKAYSAARQSLAKAWAHVPPEVWNLLWEILSVNKEHNPSRLTYVSLLARDMSEAKVALSPPQQLVTVEAMFLDGWEAKAIDNWKRCISTLGDNGAETFQDFWELGARMFCQQGDLAQAERAVNKLLERQLDPRILMPYIRSCAANPTNEARTKAWDAYRRMRDLLGTSMGLEDYDQVISFFLTTSQTEPALQAFVDMMSSGTVELKGRQRLPSHIGNKFFFGKWLKRLIGAGDLDGAYSVFNFMRSKGVEAAAIQVNGLIGAWQRSGGADDVEKADKLAWDMINARIEFVRNRRRLSSMEGPVRIVEVSKISKLGSIPKATLETFSLLAENYRVRRLQGEMDKLWDAFREAEISPDAFMMNQLMESYSQNGNVSEARELYRTLVYERQVKPDPYTFMALWKMLGANRLHNVTGEELANEVRLTREAFAEMVRFSSVFEADGLDGQLARKILHTFRRLKDNLGIVTALQAFKDVFKFTPPEVLALEMLLETTSLAWETAQARQKLRLVKRRIDAHIENRQKLLGRSTTLDEMTPKQRGDELSHYMQTVYMEEVGPVPQSHMTEVAKEMGVYDVLAGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6C5</accession>
    <name>E3Q6C5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP phosphoribosyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_01517</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090393.1">
        <property type="nucleotide sequence ID" value="XM_008092202.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6C5"/>
    <dbReference type="STRING" id="645133.E3Q6C5"/>
    <dbReference type="GeneID" id="24406882"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01517"/>
    <dbReference type="eggNOG" id="ENOG502S6WE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120084_2_1_1"/>
    <dbReference type="OrthoDB" id="15981at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036069">
        <property type="entry name" value="DUF34/NIF3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41774">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41774:SF1">
        <property type="entry name" value="NGG1P INTERACTING FACTOR NIF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102705">
        <property type="entry name" value="NIF3 (NGG1p interacting factor 3)-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00020998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="111" mass="12048" checksum="F639566083D975DD" modified="2011-01-11" version="1">MADRYKLIYTVPASHLVATKDAVFKTGAGVYDEGKYVQVAFELTGQGQFMPVAAAGADPHTGAVDQLERVLEYRVEILCVGRDVAKAAVAALKSAHPYEVPAYEVYKLEDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6I0</accession>
    <name>E3Q6I0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ran GTPase activating protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_01572</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090448.1">
        <property type="nucleotide sequence ID" value="XM_008092257.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6I0"/>
    <dbReference type="STRING" id="645133.E3Q6I0"/>
    <dbReference type="GeneID" id="24406937"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01572"/>
    <dbReference type="eggNOG" id="KOG1909">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028747_3_0_1"/>
    <dbReference type="OrthoDB" id="184583at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
        <property type="term" value="C:nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006611">
        <property type="term" value="P:protein export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000054">
        <property type="term" value="P:ribosomal subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006404">
        <property type="term" value="P:RNA import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031509">
        <property type="term" value="P:subtelomeric heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006409">
        <property type="term" value="P:tRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00116">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027038">
        <property type="entry name" value="RanGap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113:SF12">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="336"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="346"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="380"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ26428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="419" mass="45625" checksum="5DDFEFA1A3273FBF" modified="2011-01-11" version="1">MASSRKVFSLEGKGLKLDTAADLEPHIAELISTDVEEVKFLGNTLGVGACKRLGEVLATKNNLQSADLSDIFTGRLLSEIPEALTSLLTSILNLPKLTTINLNDNAFGINTQAPVVAFLAAHVPLQHLYLNNNGLGPHAGILVANALSELHAKKEEARKEGKEVPHLETVICGRNRLENGSMQAWAKAFSLHNKIKEIKMVQNGIRQEGISHLISEGLNHATELRILDLQDNTFTVSGAKAVASVLPTWTHLQELGLNDAYLTAKGTALVTKALAKGKQDKLEILRLAFNDITPKALASIASVVSSSLPALMKVELNGNKFEEEDPSVSAIREELEERKEKTGGDIVDEDAWGLDSLSDLEGDSDDEEEEESEEEEEPEPTERAEILDKEAQEAQEEPTVQLKDKEVDDLAKKLGKTEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6L9</accession>
    <name>E3Q6L9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF3074 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_01611</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090487.1">
        <property type="nucleotide sequence ID" value="XM_008092296.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6L9"/>
    <dbReference type="STRING" id="645133.E3Q6L9"/>
    <dbReference type="GeneID" id="24406976"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01611"/>
    <dbReference type="eggNOG" id="ENOG502QTT5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045430_0_0_1"/>
    <dbReference type="OrthoDB" id="6423603at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024500">
        <property type="entry name" value="DUF3074"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40370:SF1">
        <property type="entry name" value="DUF3074 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40370">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11274">
        <property type="entry name" value="DUF3074"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3074" evidence="2">
        <location>
            <begin position="109"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="331"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ26467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="365" mass="39351" checksum="73BE14BC7D09871D" modified="2011-01-11" version="1">MNTEDENLGPLVRLWGLRTEQLPAPSATSADLAPFLIAVLQEAVPFIDAVAPKDGTARPNEWKAKGNKTFPESTAPVELYERIVPAAELAKEAARNQLPNGDSVSAETWACRRSIHKDKPVKGTAAWEEFVKCFKDDHVEAEKAFTPNVMQAREALAWDCNGIVVNEGGISWGDFKLSVSEIKHRLVMPLKNRVFPELIVSAKARGADEFVVVSVPVLDLAGSDHGQLVKDKSIVVGAYVSVERVRRLPTGAIEWIMATASDAKGVLPAWIQAKAVLGVVAKDVALFLGWIAEEREKGTSVGKWTAVKGDSEARPGSTNRKASMTLEDAESSNMQGRTSRQGISSRNGTEPALGGTNGTNGHVHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6X6</accession>
    <name>E3Q6X6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NUDIX domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_02434</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090634.1">
        <property type="nucleotide sequence ID" value="XM_008092443.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6X6"/>
    <dbReference type="GeneID" id="24407799"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02434"/>
    <dbReference type="eggNOG" id="ENOG502S9V3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037162_2_1_1"/>
    <dbReference type="OrthoDB" id="10259236at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004081">
        <property type="term" value="F:bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006167">
        <property type="term" value="P:AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006754">
        <property type="term" value="P:ATP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02883">
        <property type="entry name" value="NUDIX_Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051325">
        <property type="entry name" value="Nudix_hydrolase_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21340:SF0">
        <property type="entry name" value="BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE [ASYMMETRICAL]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21340">
        <property type="entry name" value="DIADENOSINE 5,5-P1,P4-TETRAPHOSPHATE PYROPHOSPHOHYDROLASE MUTT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="31"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ26614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="198" mass="21909" checksum="B2BC9ED4A3FCCF1F" modified="2011-01-11" version="1">MTPSALSEEPEMYASTIAEMALDRKFFPSHKFIISCGTVTVDTRGKRVLLVYNKRHRIYQLPKGRKNIGEDLLAAALRETLEETAVAARPVTLRLRTRATPVSRPPGAPEVSEELVDTEPVAVCHYPDPASGAMKMVFYFVAERNFDVTPDGGTSEDRAKFDVVWVDAAKAADKLAFKEDGMVVEKALDDLRTSGYDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7U3</accession>
    <name>E3Q7U3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase</fullName>
            <ecNumber evidence="3">1.1.1.302</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_02126</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes an early step in riboflavin biosynthesis, the NADPH-dependent reduction of the ribose side chain of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, yielding 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>2,5-diamino-6-(1-D-ribitylamino)pyrimidin-4(3H)-one 5'-phosphate + NAD(+) = 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:27274"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58890"/>
            <dbReference type="ChEBI" id="CHEBI:59545"/>
            <dbReference type="EC" id="1.1.1.302"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>2,5-diamino-6-(1-D-ribitylamino)pyrimidin-4(3H)-one 5'-phosphate + NADP(+) = 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:27278"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58890"/>
            <dbReference type="ChEBI" id="CHEBI:59545"/>
            <dbReference type="EC" id="1.1.1.302"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HTP reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.302" evidence="3"/>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ26955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090975.1">
        <property type="nucleotide sequence ID" value="XM_008092784.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7U3"/>
    <dbReference type="STRING" id="645133.E3Q7U3"/>
    <dbReference type="GeneID" id="24407491"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02126"/>
    <dbReference type="eggNOG" id="ENOG502SBB8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1855117_0_0_1"/>
    <dbReference type="OrthoDB" id="3192019at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="entry name" value="Dihydrofolate Reductase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="Dihydrofolate reductase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bacterial bifunctional deaminase-reductase C-terminal" evidence="9">
        <location>
            <begin position="13"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ26955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="138" mass="15030" checksum="E30ACB572D8C5536" modified="2011-01-11" version="1">MLSMGEHNPLQKYSKESLVVASKTLKREHHPRVTIVSKDFIGYIANLKNTDGRDIWLMGGQLVGPCLDAGILDSVETAIMPMILGEGASLVGESALAPLGGIKLELVDCREWETSGIIMCKYNVSRQMAASLGEAMFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8C1</accession>
    <name>E3Q8C1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Potassium transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_02304</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the TrkH potassium transport family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091153.1">
        <property type="nucleotide sequence ID" value="XM_008092962.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8C1"/>
    <dbReference type="STRING" id="645133.E3Q8C1"/>
    <dbReference type="GeneID" id="24407669"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02304"/>
    <dbReference type="eggNOG" id="KOG1341">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005947_0_1_1"/>
    <dbReference type="OrthoDB" id="9999863at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140107">
        <property type="term" value="F:high-affinity potassium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030007">
        <property type="term" value="P:intracellular potassium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990573">
        <property type="term" value="P:potassium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003445">
        <property type="entry name" value="Cat_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004773">
        <property type="entry name" value="K/Na_transp_Trk1/HKT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015958">
        <property type="entry name" value="Trk1_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051143">
        <property type="entry name" value="TrkH_K-transport"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00934">
        <property type="entry name" value="2a38euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31064:SF30">
        <property type="entry name" value="HIGH-AFFINITY POTASSIUM TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31064">
        <property type="entry name" value="POTASSIUM TRANSPORT PROTEIN DDB_G0292412-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02386">
        <property type="entry name" value="TrkH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002450">
        <property type="entry name" value="K+_transpter_TRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0630">Potassium</keyword>
    <keyword evidence="4 10" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="27"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="447"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="521"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="583"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="648"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="706"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="127"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="257"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="366"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="821"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="875"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="128"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="138"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="204"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="257"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="328"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="370"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="821"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="875"/>
            <end position="892"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR002450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ27133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="918" mass="102875" checksum="FB2DF67B1F81A471" modified="2011-01-11" version="1">MLEASRGWLLAQLWAAKPSFISKKPHFNFISAHYIWICSLTILGSVLIYATAGGQMAYIDALFFASGANTQAGLNTIDVNLLNTFQQACLYFFTMTSNPITIHSSVVFLRLYWFEKRFQGIVREARQRRNTMSKSKSRARDELSQAERGRLNVRNIKVMHTNGHRSRMTNDGILLSTKEDEDGRVSPGSNGIGPAPAQQSPRDQTPDRASDHHDDDAHGTDLSQGRITFAQHVFRSDGTEPEVKLPPPHSPAHLAILERQRNGPEETLRIPNPRDAERGMKPKRVEDNAAPEPEDERDDGIPHTRVAAGETNDMSHGLGNNAFRRPTIKIEEPERPREPERSVKDEIADEAEVIGRTIFPFSLRKPNLHRKGDEKTRGEDGTSETPLARVRSRTFDTIRTALTRDKIEDMPYLSFTPTMGRNSAFPGLTLEQREELGGIEYRSLRTLAVILLCYFWGFSLFAVTCFLPWIYTSSNAKYAGLVESSGVSKAWWGIFTANSAFNDLGLTLTPDSMNSFNDATFILLIMSFLIIIGNTGFPIMLRVIIWIMSKIVPKGTGLWEELRFLLDHPRRCFTLLFPAGATWWLFIILIGLNVLDLLFFVLLDLNDNAVSHLPVHIRVLDGIFQAASTRTAGFSVVNISLLHPAVQVSYMIMMYISVFPIAISIRRTNVYEEKSLGVYHSPDEDVEGTNENSAWSYVGTHLRRQLSFDLWYVFLGLFILAITEGRRIQAKDFDVYSVLFEIVSAYGTVGLSLGYPNINASLCSQFTTGGKLIMIAMQIRGRHRGLPYGLDRAVLLPSESRFEKEAEEAHPVLVRSATGASTGTALSAARSHLRSRRMSTNRGQGNIITQFLHPGPVIPHEDSLTDLSRHTRSFAVDEHPPMGENMKRRNTEPAEDDITSSDSETAGPPRRVFTTPAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8S6</accession>
    <name>E3Q8S6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_01935</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MSOX/MTOX family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091460.1">
        <property type="nucleotide sequence ID" value="XM_008093269.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8S6"/>
    <dbReference type="STRING" id="645133.E3Q8S6"/>
    <dbReference type="GeneID" id="24407300"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01935"/>
    <dbReference type="eggNOG" id="KOG2820">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007884_0_2_1"/>
    <dbReference type="OrthoDB" id="2219495at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051698">
        <property type="term" value="F:saccharopine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008115">
        <property type="term" value="F:sarcosine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045170">
        <property type="entry name" value="MTOX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10961:SF26">
        <property type="entry name" value="L-SACCHAROPINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10961">
        <property type="entry name" value="PEROXISOMAL SARCOSINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="6">
        <location>
            <begin position="8"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ27440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="417" mass="45504" checksum="E20FF5FDFD605B0B" modified="2011-01-11" version="1">MLTYHDPILVVGGGTFGLSTAYHLVKAGYTSVTILEQGTSVPSTLSAGNDVNKIVRAEYEDPFYTELALQAMAEWNNNPVFSPHYRQTGYLLANSAAAPAKTKRTLQKSLESIRAHPAWVGRIVPVKSRDDIAQAAPALDGPMEGWEGYYNSFAGYAHASNALKALYEYVKDRGVNIHTGEEVSSLVYDNDQCVGARTVSGKEYKAIATILTLGASLGKVLPSVKRQITAKAWSVLHIQLRPEEAEQLKGIPVTYARDLGFFFEPEPGTGILKLSPSGGGYTNYSTATGLSLPPKNNDFVPEADRQRVRKLLQETLPSLADRPFVDQHICWCADSADSDYVIDAVPGRKGLFVATGDSGHGFKMLPVVGEWIKDLIEKGSQELPRWSWKEGSDAGQNVSWRAGEVLDLKNLGFSPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8S9</accession>
    <name>E3Q8S9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_01938</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091463.1">
        <property type="nucleotide sequence ID" value="XM_008093272.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8S9"/>
    <dbReference type="GeneID" id="24407303"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01938"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_3_1"/>
    <dbReference type="OrthoDB" id="2250022at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF92">
        <property type="entry name" value="AGL026WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="199"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="290"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="319"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="1"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ27443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="375" mass="40383" checksum="A39628BA770A49F8" modified="2011-01-11" version="1">MSFSGGRGVLCACSGAAYGLGGLLATRFLLGLVQAAFYPGCVATLSSWYIRKELGVRVGLFYTGSMLSGAFSGLIAAAITKGMDGTGGLLAWRWVFIVEGALTVVIAIGAYAMLPDFPANTKWLTSQEQQLAVWRMEIDAAGEKDWTSSSSQPLFDGFRMIIVDPVNWILVLIVYGTASSISINSFFPTIVGSLGKDRITTLLLTSPPYLLACIVCAAVSWNAGRTNERFWHTVGPLTCALVGFIVSGAATDVTSRYLGAMIMLPGIYTGFNMSMVWTANTIYRPAAKRAAAVAFNNAVSTMSSIYGSYLYPNDAAPRFILAFSVNAGMAFMAIVASTVLRFVLKRENHRLAVQEQEMDAKGPMRIVGRGFRYMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8U3</accession>
    <name>E3Q8U3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Lysr family regulatory protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_01952</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the plant acyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091477.1">
        <property type="nucleotide sequence ID" value="XM_008093286.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8U3"/>
    <dbReference type="STRING" id="645133.E3Q8U3"/>
    <dbReference type="GeneID" id="24407317"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01952"/>
    <dbReference type="eggNOG" id="ENOG502S6KB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029797_2_1_1"/>
    <dbReference type="OrthoDB" id="21502at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051283">
        <property type="entry name" value="Sec_Metabolite_Acyltrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31896">
        <property type="entry name" value="FAMILY REGULATORY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G14730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31896:SF69">
        <property type="entry name" value="FAMILY REGULATORY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G14730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="445"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="447"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ27457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="555" mass="62257" checksum="97A9FCA3E6866B61" modified="2011-01-11" version="1">MDYMRSLVGANTKKIQVPKVATDDVYPVHFFDDTKPFREMLLNWTLRFDDVLDAEKLHLSLAKLLDIGDWRKLAGRMRLTKDNKLELHVPHKFTPARPAVRFSHVVHNMSITEHKHAKNMPRTTTTPSIQPGVVNFYSLGAREGAPRTLEDLISSDEPGIALHVVSFNDATLVGLLFSHVLFGAAGMQALVEAWSQVLAGREAEVPVLHGARRDILDDVGVDTDPEKEKLLLDRRVLKGFRHFRFSLRFLWDIMRRPEIESKILCLPGDFVANLRSQAMADLHAMDEKGMGTGEAPFVSEGDVLTAWWTRIVCLARGSNRPVTVLNAVDITGRLKGVFAPGKLYVQNFALGTWTLLSSAEVLKAPLGYVARCFRYDIQTQTTPSQLMAFMRRIRQRGRCKTQPLYGDPNSMLIIFTNWSRCKFFDCIDFAPAVIPSINPIAELPAASENTQPNSDDSITSDGISNGGADLEKQANNASIAQVLSRPPPGKISYHHSMTRTRTILSRNVFTILGKDLNGNYWVSALGHPECWDKLEKEVEISSMDNLRRLRPETTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q996</accession>
    <name>E3Q996_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF8035 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_01770</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091295.1">
        <property type="nucleotide sequence ID" value="XM_008093104.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q996"/>
    <dbReference type="STRING" id="645133.E3Q996"/>
    <dbReference type="GeneID" id="24407135"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01770"/>
    <dbReference type="eggNOG" id="ENOG502T57W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1147116_0_0_1"/>
    <dbReference type="OrthoDB" id="5430750at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058348">
        <property type="entry name" value="DUF8035"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26118">
        <property type="entry name" value="DUF8035"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF8035" evidence="2">
        <location>
            <begin position="40"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ27275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="242" mass="26985" checksum="FC95713A4EB909CE" modified="2011-01-11" version="1">MPRKRKQIRFEEGGDEDWSGSSSNSSRSSIASFHRESYPKNGKTRIPAKLVSKRALIDLGYPFVEEGTTVVLLVALDERLIDEVLKLSEEYRRSDAEIEDHSSGKPIDYPRDRGFDWVNVELPAEEGSLQYSAHDEASDDDLDSAFGDIGHDEHEGPIAHSGVLSLNTTKAFGENAFDLTAGRFPSWNQEKSELINGTTHLYSVHAAEFYMDRAGNQRVTLVCPNDPGNGLSAPSLVRMRWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9J7</accession>
    <name>E3Q9J7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_01871</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091396.1">
        <property type="nucleotide sequence ID" value="XM_008093205.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9J7"/>
    <dbReference type="GeneID" id="24407236"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01871"/>
    <dbReference type="HOGENOM" id="CLU_2236399_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="105" mass="11544" checksum="138DBBE2FB9DDA1E" modified="2011-01-11" version="1">MLAVGGKLLDQDLILVDSETRDMPSEGVEEPSEVAAVGEEIYAHWHRFKDDHQDLLSAPATKLIKLIHKLHKSEMMKSFQVSWATPQSSEARPMADEGAEGATGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9S2</accession>
    <name>E3Q9S2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_02754</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091630.1">
        <property type="nucleotide sequence ID" value="XM_008093439.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9S2"/>
    <dbReference type="GeneID" id="24408119"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02754"/>
    <dbReference type="eggNOG" id="ENOG502T4XI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_117269_0_0_1"/>
    <dbReference type="OrthoDB" id="5239396at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ27610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="204" mass="23029" checksum="C512BD3ADA3316E7" modified="2011-01-11" version="1">MLQLSTLSSRAGYSPLVPSPLNPQVHAIAPQRYQRLREKRRQQSRGDVSPTQRLLRHKAAMAWKSEALTRESTIYTREEILDIIAECDRQDAAARGNAAITTTATSDDNNKYKQAEKQHPQVHIRAAHWKEHNGEEYDFFCEADEFDAGDADEGSLQWSSFVPRPFSKDTARRVVLAFGLMCICGCLPVLRANGFHIYPATETP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9U7</accession>
    <name>E3Q9U7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Altered inheritance of mitochondria protein 41</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AIM41</name>
        <name evidence="2" type="ORF">GLRG_02779</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the AIM41 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091655.1">
        <property type="nucleotide sequence ID" value="XM_008093464.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9U7"/>
    <dbReference type="STRING" id="645133.E3Q9U7"/>
    <dbReference type="GeneID" id="24408144"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02779"/>
    <dbReference type="eggNOG" id="ENOG502SDB7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079430_0_0_1"/>
    <dbReference type="OrthoDB" id="538640at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016884">
        <property type="term" value="F:carbon-nitrogen ligase activity, with glutamine as amido-N-donor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1510.10">
        <property type="entry name" value="Uncharacterised protein YqeY/AIM41 PF09424, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003789">
        <property type="entry name" value="Asn/Gln_tRNA_amidoTrase-B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023168">
        <property type="entry name" value="GatB_Yqey_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019004">
        <property type="entry name" value="YqeY/Aim41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042184">
        <property type="entry name" value="YqeY/Aim41_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28055">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 41, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28055:SF1">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 41, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09424">
        <property type="entry name" value="YqeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89095">
        <property type="entry name" value="GatB/YqeY motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU365099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="196" mass="20950" checksum="04B0148DD11E5B17" modified="2011-01-11" version="1">MASRSLVRLQTLLRPTVLSRAAATPLRALRLYSSDAAPAQPRLLATLKTDLKTAMRAKDAPRLSVLRSVLSATNNAAKTNAPIATDAQLVALLRKTQRATQEAAAQFRAAGRDDLADKEDLQAKVMAEYIATSGVVTVTEADVRVLIQKAIGDAAAAGKNGLGEVMKLINVAIQGKDLEIDRKRVADLVKEALKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9V1</accession>
    <name>E3Q9V1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="14">SNF2 family domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_02783</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091659.1">
        <property type="nucleotide sequence ID" value="XM_008093468.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9V1"/>
    <dbReference type="STRING" id="645133.E3Q9V1"/>
    <dbReference type="GeneID" id="24408148"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02783"/>
    <dbReference type="eggNOG" id="KOG1001">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000315_2_7_1"/>
    <dbReference type="OrthoDB" id="448448at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18008">
        <property type="entry name" value="DEXDc_SHPRH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF52">
        <property type="entry name" value="SINGLE-STRANDED DNA-DEPENDENT ATPASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="446"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="11">
        <location>
            <begin position="816"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="927"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="485"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="897"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="20"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="897"/>
            <end position="906"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ27639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1103" mass="122226" checksum="9567F4BC943090C3" modified="2011-01-11" version="1">MNPQPQSWNPQALLNPRAYASSTPASKRNSPKPQSLATRSAPANQSANSGAFVFQFASPNDTPSESLTPGMTSGASTPGHDGRVSPYGMGSMIERMKDVQERASAPQPKRRKYDTPESDADNKKTMGPGGSGMLGAYVKEKQDAGKKENAKVSTNTVDLTEGDDDVVMVQDPAAEEVCYGMLTAKLDCHKVPSPKPGTQSIFGPDFMPPVKIVLKRIIGDSTKKIQAYDYTRDIIGNIDAHTAGALVPLLDSNVRLRTDCKIPTHRKQADEESGKPISRSYPVEMTLYGQYRFVKAVGKHFERAKIILRHPTRVDSGVRYENVHAESKPIPAPGARNLAGALAQYNSHSSSTYYTNPTPRTVEEIRSDVMGVFDSMGKTDELPEMDPSPIVTTELLKHQKQGLYFMANKEKTSSAEERTKGSMWQLKIGPSGQKSYYNVITGQAERQLPPDTHGGLLADMMGLGKTLSILSLLASSMDEAREWASRAPVQPEMPPQKAGGKATASSSLPLTNIALNSKATLLVCPLSTVTNWEEQIKQHIAPGQMSYYIYHGSNRIKDVEKLADFDLVITTYGSVSSELGARSKRKSGKYPLEEIGWFRIVLDEAHMIREVATLQFKAIVRLQAARRWAVTGTPVQNRLEDLAALLQFIRLKPFDDRNKFNRFIVDPFKACDTEIVPKLRVLVDSVTLRRLKDKINLPPRSDHVVKLDFTAEEREVYDLFEKNAQDRVKVLAGNGVQRALGGHTYIHILRSILRLRLLCAHGKDLLNEEDLEALQGMTADMAIDLDSEDEDNQPGLSNRKAYEMFELMQETNTDACSVCSKKLGSNDDASIESEGQEDILGYMTPCFHIVCGACIRGFKEQTKQLLAPGEATGPCPVCSTVIKPAYVDIRRSRVKIEHEGPAKDKTSSNGRKTFGKYSGPHTKTRALIEDLLKSKADSEASPHEPPYKSVVFSTWTSHLDLIQMALDNVGIKYVRLDGSMTRVARTQAMDSFRDDNSVHVILVSITAGGLGLNLTAGSSVYVMEPQYNPAAEAQAIDRVHRLGQKRPVRTVRYIMRNSFEEKMLELQEKKNKLASLSMDRKDRVFDKSEAARQRLQDLRSLFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3QA70</accession>
    <name>E3QA70_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DUF1014 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_02902</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCDC124 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091778.1">
        <property type="nucleotide sequence ID" value="XM_008093587.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QA70"/>
    <dbReference type="STRING" id="645133.E3QA70"/>
    <dbReference type="GeneID" id="24408267"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02902"/>
    <dbReference type="eggNOG" id="KOG3223">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069723_1_1_1"/>
    <dbReference type="OrthoDB" id="76412at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010422">
        <property type="entry name" value="Ccdc124/Oxs1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054414">
        <property type="entry name" value="Ccdc124/Oxs1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054413">
        <property type="entry name" value="LSO1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21680">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21680:SF0">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06244">
        <property type="entry name" value="Ccdc124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22048">
        <property type="entry name" value="LSO1_2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LSO1/LSO2" evidence="5">
        <location>
            <begin position="10"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Coiled-coil" evidence="4">
        <location>
            <begin position="114"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="28"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF22048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ27758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="222" mass="23933" checksum="4B84F0C16E1E3A7D" modified="2011-01-11" version="1">MAGKKGADNSKKAAGNARKAESAAQKAAAEDAKKAAAEDAEWSKGAKGNAKKEAEAAKKAEAARKKAEKDALLKEEEANTPGRPGPKNAKTAVKKTRGLDLSQLDDDRSGGSLGALNATGIDNALDALSLTTSDAAKVDRHPERRFKAAYAAFEERRLKEMDNDGTGQGLRLQQRKDKIRKEFEKSPENPFNQVTAKFDATKEELAEIKQKEKSKIEARLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAH2</accession>
    <name>E3QAH2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DEUBAD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_03004</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ27860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091880.1">
        <property type="nucleotide sequence ID" value="XM_008093689.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAH2"/>
    <dbReference type="STRING" id="645133.E3QAH2"/>
    <dbReference type="GeneID" id="24408369"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03004"/>
    <dbReference type="eggNOG" id="ENOG502S8M1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058853_0_0_1"/>
    <dbReference type="OrthoDB" id="2289918at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028020">
        <property type="entry name" value="ASX_DEUBAD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044867">
        <property type="entry name" value="DEUBAD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13919">
        <property type="entry name" value="ASXH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51916">
        <property type="entry name" value="DEUBAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DEUBAD" evidence="9">
        <location>
            <begin position="106"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="59"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="259"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="27"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="65"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ27860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="322" mass="35795" checksum="F590E4E6B915720F" modified="2011-01-11" version="1">MADYASSLPTAGLSPPPFSEGSEYENVHQQSQQTSPDQAPALVDNINLDPTFTATELDSMRRSARNTNKPKTVIVTSPSRPTKRKITTRVMKKTPKWTTQKLLTDPKSPLANADLRTILCQPAAWDILSKEERAEIIALFPPGTRILDPDTENARLDLDSLRNDNNFRHDCATYTDNIAMGKHDPEWLEQAFAARERRRAGDFDSYLKQKFEDEWSCELPEGFGLNRDGNGPTNGVTAAEEQRKEEGETQMEAKVKNAEGTEYAEVTQEQPNKDTRMIDEGDSEEVVDVKLGSPASQTHEIQLGSPIPEESGVKLGSPIPEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAL7</accession>
    <name>E3QAL7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF410 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_03049</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GET4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ27905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091925.1">
        <property type="nucleotide sequence ID" value="XM_008093734.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAL7"/>
    <dbReference type="STRING" id="645133.E3QAL7"/>
    <dbReference type="GeneID" id="24408414"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03049"/>
    <dbReference type="eggNOG" id="KOG3024">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046061_0_1_1"/>
    <dbReference type="OrthoDB" id="10252405at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072380">
        <property type="term" value="C:TRC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045048">
        <property type="term" value="P:protein insertion into ER membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000272">
        <property type="entry name" value="DUF410 domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007317">
        <property type="entry name" value="GET4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12875">
        <property type="entry name" value="GOLGI TO ER TRAFFIC PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12875:SF0">
        <property type="entry name" value="GOLGI TO ER TRAFFIC PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04190">
        <property type="entry name" value="GET4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="306"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ27905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="329" mass="35920" checksum="E134B0E3E16AC809" modified="2011-01-11" version="1">MAAKGDKIEKIIARLQARIGEGQFYEAQQQTRVVAARYIKAANWPAATDILYNVAQSLLKAGQGGSGGDLAVMLVDVFRQAELKPDAASKGKLLTLLRLFPAQEPTRKKFIGEMIAWSAKFGEYPAGDADLHHVTGSLYAEEHEAYEAERHLVLGTKDSAEVLAKMEYVWYKEDDSHTAPLYASRAILPYLLVGNVRAANTCYRVFTSSLSDDNKGLGVQDVSSNSADLRIFPGLPLLNFLGLLLLAVQRGAPDAYKQLLAKYSSNIAEVGAWNEALEIIAEMYFGIQRPKQSNPLMDMMGSLFGGAGAPQQRRPATRRVEAPAAEGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QB16</accession>
    <name>E3QB16_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_03198</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ28054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092074.1">
        <property type="nucleotide sequence ID" value="XM_008093883.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QB16"/>
    <dbReference type="GeneID" id="24408563"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03198"/>
    <dbReference type="eggNOG" id="ENOG502SZ93">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1602572_0_0_1"/>
    <dbReference type="OrthoDB" id="3926238at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ28054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="166" mass="18976" checksum="DC477F27A0D43A4E" modified="2011-01-11" version="1">MCQYYAHAFTCKHLSFTFARFCQPASLIQKPCAKRQVWQTISLDDACEDCLMWFPDRMLRHTEDTFSTWAPATEVFEADGRSIFVAVISSRNGTVLCAKEAGSVESRYGRRAAEWSNSLYEQVREQQEPSQLQTRSTGNYQASREYGYLIDTELSRSVFEVGVPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBQ8</accession>
    <name>E3QBQ8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxidoreductase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_03541</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092417.1">
        <property type="nucleotide sequence ID" value="XM_008094226.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBQ8"/>
    <dbReference type="STRING" id="645133.E3QBQ8"/>
    <dbReference type="GeneID" id="24408906"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03541"/>
    <dbReference type="eggNOG" id="KOG2742">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023194_3_1_1"/>
    <dbReference type="OrthoDB" id="64915at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006740">
        <property type="term" value="P:NADPH regeneration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840:SF5">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="1">
        <location>
            <begin position="4"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase C-terminal" evidence="2">
        <location>
            <begin position="155"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ28397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="347" mass="37345" checksum="98BDA6E2A3CB4837" modified="2011-01-11" version="1">MAPIGVAIVGGGIFAKEQHLPAVEASDQLTLKAIYSRSRKSAEDTAKLATNSASPDLYSDDSGDGKSFEDLLARDDIQALILALPIVNQPEYIEKALAAGKHVLAEKPIAPDVARAQKLIDYYNKVSAEKGVTFAVAENYRFQPRYTAARDEVQTLGKIIGFNVRVFFYVQLGGKYIETTWRKKPDYQGGFLLDGGVHFAAALRLLLGKEAAADSVAAFSDLTQEHLPPIDTINAAIRTRSGATGSFAVSVGSSLSAFDFQVAGEKGSVTLSGHDLTVKLFDGEARTIQFEQTSGVKEEVKAWAEGLVAGRPNPLQSPEEALADLELLEKIFKSGEKDGAVQKLQLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCJ8</accession>
    <name>E3QCJ8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Eukaryotic translation initiation factor 6</fullName>
            <shortName evidence="6">eIF-6</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">TIF6</name>
        <name evidence="7" type="ORF">GLRG_03730</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer. Associates with the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleolus</location>
        </subcellularLocation>
        <text evidence="6">Shuttles between cytoplasm and nucleus/nucleolus.</text>
    </comment>
    <comment type="PTM">
        <text evidence="6">Phosphorylation at Ser-174 and Ser-175 promotes nuclear export.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the eIF-6 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092606.1">
        <property type="nucleotide sequence ID" value="XM_008094415.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCJ8"/>
    <dbReference type="STRING" id="645133.E3QCJ8"/>
    <dbReference type="GeneID" id="24409095"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03730"/>
    <dbReference type="eggNOG" id="KOG3185">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071894_0_0_1"/>
    <dbReference type="OrthoDB" id="4155914at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902626">
        <property type="term" value="P:assembly of large subunit precursor of preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042256">
        <property type="term" value="P:cytosolic ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000466">
        <property type="term" value="P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000054">
        <property type="term" value="P:ribosomal subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00527">
        <property type="entry name" value="IF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.75.10.10:FF:000001">
        <property type="entry name" value="Eukaryotic translation initiation factor 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.75.10.10">
        <property type="entry name" value="L-arginine/glycine Amidinotransferase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00032">
        <property type="entry name" value="eIF_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002769">
        <property type="entry name" value="eIF6"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00323">
        <property type="entry name" value="eIF-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10784">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01912">
        <property type="entry name" value="eIF-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006413">
        <property type="entry name" value="IF-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00654">
        <property type="entry name" value="eIF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55909">
        <property type="entry name" value="Pentein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="modified residue" description="Phosphoserine; by CK1" evidence="6">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphoserine; by CK1" evidence="6">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ28586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="246" mass="26612" checksum="788B213B6AB5326D" modified="2011-01-11" version="1">MAVRAQFENSNEIGCFATLTNSYALVAPGASENFYSVFEAELQGVIPICRASIAGVRIIGRLTAGNRKGLLVPNTTSDQELQHLRNSLPDEVRIQRIEERLSALGNVIVCNDHIALIHPDLERETEEIIADVLGVEVFRQTIADNVLVGSYMSLTNQGGLVHPKTSIQDQDELSSLLQVPLVAGSVNRGSNVVGSGMVVNDWMAVTGLDTTATELSVIESVFRLGEGLGPDNVNTKLKDTMVESFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCK2</accession>
    <name>E3QCK2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">LMBR1 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_03734</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LIMR family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092610.1">
        <property type="nucleotide sequence ID" value="XM_008094419.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCK2"/>
    <dbReference type="STRING" id="645133.E3QCK2"/>
    <dbReference type="GeneID" id="24409099"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03734"/>
    <dbReference type="eggNOG" id="KOG2296">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016542_1_0_1"/>
    <dbReference type="OrthoDB" id="203099at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051584">
        <property type="entry name" value="GPCR-associated_LMBR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006876">
        <property type="entry name" value="LMBR1-like_membr_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21355">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR-ASSOCIATED PROTEIN LMBRD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21355:SF0">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR-ASSOCIATED PROTEIN LMBRD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04791">
        <property type="entry name" value="LMBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="15"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="135"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="164"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="359"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="408"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="450"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="501"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="584"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="659"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="595"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="687"/>
            <end position="701"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ28590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="701" mass="79452" checksum="91CB8BDEE4F547BF" modified="2011-01-11" version="1">MFHVVSASSPVPSEIFALLALLLISVIVLLILRHFLPLRTTPAFYLVPIFFALWLPACMVLLVPIDLASSARTDDEATRGIWLPQRLLLVSWRITYWLTFALTWFILPILGEYSDSGYREPNDCLKYSLRQNAQYHAMVLGTAAVGLAYLFIRYNPSPTTLKTSFMALAYFYGLVFAIYLMGHGLVAVPRRLFRYSSISGRLRRLQIRAPKLYEKMEDSLLNLEDIELQVSELGRRKTGSAVKFSEWIDELVESANMPESQPRTAVGSVDSRALPTVITEKFMADLSRRLMRARHARSRYVNDWNDLLKEASETQAILDSAASKKLEFSSPSPHAGFWDRFTIHTPYTRYLYYYHFEPYACIALGAFLAVASALIIWSEVIKAAFPQLSVIRLTVVHHWVGEKGQVGFAGQLISVLWLLYMCAATFITMTEVKTWRGRALVRRNTAYESAFWYSGQVAKLSVPLSYNFMTFLSRDIYQKTRFYSFLGQLIDFTAMGRWADYLFPIFVLLPVAATLFGLYGKIKRLFGFGGEFIDDDDNGDGRVFGTGSWREGRDLIERELGGNSALRRREEAFARLESTGRSAPVLTIPGGRTGAAASPARSPVRAVHNRQPGQLARNRHYRDDEPEEDQNFFESLGHRMKNTMDTFEAPQWFQEIKKPKWLGGDDDEPSSSSRGGTARGGDGGVESDIRRWFGGEGRVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCK5</accession>
    <name>E3QCK5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Legume-like lectin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_03737</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092613.1">
        <property type="nucleotide sequence ID" value="XM_008094422.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCK5"/>
    <dbReference type="STRING" id="645133.E3QCK5"/>
    <dbReference type="GeneID" id="24409102"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03737"/>
    <dbReference type="eggNOG" id="KOG3839">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041093_1_1_1"/>
    <dbReference type="OrthoDB" id="270293at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005793">
        <property type="term" value="C:endoplasmic reticulum-Golgi intermediate compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005537">
        <property type="term" value="F:D-mannose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07308">
        <property type="entry name" value="lectin_leg-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.200:FF:000095">
        <property type="entry name" value="Lectin family integral membrane protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051136">
        <property type="entry name" value="Intracellular_Lectin-GPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005052">
        <property type="entry name" value="Lectin_leg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12223:SF45">
        <property type="entry name" value="RE50040P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12223">
        <property type="entry name" value="VESICULAR MANNOSE-BINDING LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03388">
        <property type="entry name" value="Lectin_leg-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51328">
        <property type="entry name" value="L_LECTIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0430">Lectin</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178367" evidence="8">
        <location>
            <begin position="23"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="276"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="L-type lectin-like" evidence="9">
        <location>
            <begin position="20"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="249"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="250"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ28593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="310" mass="34640" checksum="C97BB924AF19DA4B" modified="2011-01-11" version="1">MWFKQSLSALWLAAMALGTAKADDEVKSIAPYLDSDMASRWYDFGGDTIIRTDSYIRLTSDRPSQTGWLFSRVPLTATNWEIEVEFKIHGKNQLYGDGFAMWITKNRGQSGTVFGSPDNFEGLGIFFDTYKNNRPGTVFPYVMAMYGDGKTSYDKDNDGKNTELAGCSARGIRHASVPTKAKVTYFQDKLLKLELQYKTEGEWTLCFETNEPPAIPQITYLGFSAETGELSDNHDIISVQAKNLYTTQAGKSNSKTTPGSGKKGSSIKKESGGGSWTWTFFKIFLFFGVLGGGYVGYTAWRAKNDKRHRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QD09</accession>
    <name>E3QD09_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_03925</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092801.1">
        <property type="nucleotide sequence ID" value="XM_008094610.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QD09"/>
    <dbReference type="GeneID" id="24409290"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03925"/>
    <dbReference type="eggNOG" id="ENOG502T211">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3069186_0_0_1"/>
    <dbReference type="OrthoDB" id="3443409at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ28781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="54" mass="6123" checksum="89CD637E3055B1E1" modified="2011-01-11" version="1">MCEYTKNYYIYTSCIDPGAHFFRTSMDGNRSRACCNGPHERYIVVPGHCPLCSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QD65</accession>
    <name>E3QD65_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Methyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_03981</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092857.1">
        <property type="nucleotide sequence ID" value="XM_008094666.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QD65"/>
    <dbReference type="STRING" id="645133.E3QD65"/>
    <dbReference type="GeneID" id="24409346"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03981"/>
    <dbReference type="eggNOG" id="KOG3010">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049344_4_0_1"/>
    <dbReference type="OrthoDB" id="10027013at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051052">
        <property type="entry name" value="Diverse_substrate_MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44942">
        <property type="entry name" value="METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44942:SF4">
        <property type="entry name" value="METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="4">
        <location>
            <begin position="50"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ28837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="292" mass="32556" checksum="F571451F1325CFE5" modified="2011-01-11" version="1">MSPTTLHQGAAKGFADAATYDAYRPSYSPEATQKFLSHLRLADVPHARVLDLAAGTGKMTEVLAARHEGFEIVAVEPHEGMRAELEKKGLPGVEVKDGFAAKLPLGEEWADGAIVAQAFHWFATPEALKEIHRVLKPTAVLGVIWNIEEYNKPQHWKASTPWENALNELVFSLGSDGQSRFRDFVWKDVFDNQLDSNPLRAVKDVIMEGGRKMPLFSVPLGEEKVPFTVWLTPEALWNRLRTLSQIAILEGDAARVFKEKFDAIVTGESVERNEKGEVLLHGVTYLAWTSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDJ8</accession>
    <name>E3QDJ8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">HMG box protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_03847</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092723.1">
        <property type="nucleotide sequence ID" value="XM_008094532.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDJ8"/>
    <dbReference type="STRING" id="645133.E3QDJ8"/>
    <dbReference type="GeneID" id="24409212"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03847"/>
    <dbReference type="eggNOG" id="ENOG502S16X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022445_0_0_1"/>
    <dbReference type="OrthoDB" id="2307332at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01389">
        <property type="entry name" value="HMG-box_ROX1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051356">
        <property type="entry name" value="SOX/SOX-like_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45789">
        <property type="entry name" value="FI18025P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45789:SF2">
        <property type="entry name" value="FI18025P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="5">
        <location>
            <begin position="150"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="150"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="76"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="205"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="236"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="249"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ28703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="455" mass="50903" checksum="94DF3609FD7F87E9" modified="2011-01-11" version="1">MPYDQNSPYSHRANESQMSYHHGYDTSVGSIYAPMSGELNHQPYSTPDTSPPTPSRASDVLTTRSGLNIHKGSSTIKPLAARANRIEKSTPKKKKERAKSSKKVDGVTKPLSELAKEQPHIPVADIGAYVQRSAEARMKEVEESKTPGRIKRPMNAFMLYRKAYQNLAKGLCTQNNHQVVSQVCGSGWPLEPEHVRDQFNEWAKEERANHQKAHPGYKFTPSKPRPKAREEEESEHGDLDDLEWGHSRASSRSRQLRKPTHGRNEAPASIFHNYPSLQTSPMGLGVQTQSMYHYSNPGKPLPAPYSQNGLGGGQYYQQSVHQRQDATGFVEDVLIRKTPSPAMGYAAPSMDNRYDGMGQYGPMSHHDGFEPMIDPGLMGHGGHPYGDPYGDPMLEPRWTNPLGFGDGRHDLLDGLSGYDEGLMHDPQLQILRGQESSWRVEELEGSHFNNWIDPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDR1</accession>
    <name>E3QDR1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_04143</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ28999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093019.1">
        <property type="nucleotide sequence ID" value="XM_008094828.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDR1"/>
    <dbReference type="STRING" id="645133.E3QDR1"/>
    <dbReference type="GeneID" id="24409508"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04143"/>
    <dbReference type="eggNOG" id="ENOG502SI13">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031053_0_0_1"/>
    <dbReference type="OrthoDB" id="5288318at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ28999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="412" mass="45726" checksum="ED428B165BCB47E1" modified="2011-01-11" version="1">MVVFVDLDEDMEPLHVLEARRLAAAAAVATDSLEPSSRGLNRELEKPASAPLVSVASVPAPQPTPTFRSAATEAFGCYPIVMSIAKHIDLNTLDSLARTSRQIRRGLLQYRSILLSSTLHCSNEDVPVDPESTFRFRARAGNWYYMEDGRNYNGKSGSCARDLVTECRRCRTVVCRNCAIKPPAHNALRERHRRLCNPCTKAPIATLVNDALEPDTSLLDDAVRREICRCEIDGVWLCQPCGRSMRGADHDYQRVWKWRAHYGEVLGGLGTGIGEGDRGVTCGRESACAGAKERENETDCDAEDAAVSGKNLWTATDQVHLDTVRYERTPSPQLGPGYERHEIEGIGGCVKTKLIRMVRVGACVPEWDDEKSQHKILAREVKGTRRSWCGWCYRVIPGETDLAKVGIKMSQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QE21</accession>
    <name>E3QE21_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein L7Ae/L30e/S12e/Gadd45 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_04253</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL30 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093129.1">
        <property type="nucleotide sequence ID" value="XM_008094938.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QE21"/>
    <dbReference type="STRING" id="645133.E3QE21"/>
    <dbReference type="GeneID" id="24409618"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04253"/>
    <dbReference type="eggNOG" id="KOG2988">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_130502_0_1_1"/>
    <dbReference type="OrthoDB" id="1928736at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030627">
        <property type="term" value="F:pre-mRNA 5'-splice site binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048025">
        <property type="term" value="P:negative regulation of mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.30:FF:000001">
        <property type="entry name" value="60S ribosomal protein L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00481">
        <property type="entry name" value="Ribosomal_eL30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000231">
        <property type="entry name" value="Ribosomal_eL30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039109">
        <property type="entry name" value="Ribosomal_eL30-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022991">
        <property type="entry name" value="Ribosomal_eL30_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002172">
        <property type="entry name" value="PRK01018.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11449">
        <property type="entry name" value="RIBOSOMAL PROTEIN L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00709">
        <property type="entry name" value="RIBOSOMAL_L30E_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00993">
        <property type="entry name" value="RIBOSOMAL_L30E_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="4">
        <location>
            <begin position="13"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ29109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="110" mass="11809" checksum="D64D4B0AB5032F77" modified="2011-01-11" version="1">MAPVKKSKKDQNSINSKLALVIKSGKVILGYKSTLKSLRTGKAKLILIAGNTPPLRKSELEYYAMLAKTPVHHFSGTNIEMGTACGKLFRCGTMAILDAGDSDILSDQVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEC2</accession>
    <name>E3QEC2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Exosome complex subunit Rrp46</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_04372</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNase PH family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093248.1">
        <property type="nucleotide sequence ID" value="XM_008095057.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEC2"/>
    <dbReference type="STRING" id="645133.E3QEC2"/>
    <dbReference type="GeneID" id="24409737"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04372"/>
    <dbReference type="eggNOG" id="KOG1069">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063514_2_2_1"/>
    <dbReference type="OrthoDB" id="27298at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071051">
        <property type="term" value="P:poly(A)-dependent snoRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11372">
        <property type="entry name" value="RNase_PH_RRP46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050080">
        <property type="entry name" value="RNase_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953:SF1">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0271">Exosome</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="6">
        <location>
            <begin position="10"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ29228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="243" mass="26258" checksum="45AF5B06CFDD9491" modified="2011-01-11" version="1">MAQNLNPQARISHLPRADGSATFSRGGYCVVSSVNGPMEVQRRDENPFESVVDVVVRPAAGVGGTGERQLENILQSALRQLIPVKNFPRCLIQITLQVTETPQNDYANSKVVQAQSSLTLLPALFHSAVLSLLSAAVPLKAIATCTTLAILEDGSKIIADPSPLEADHAKSLHVLSFTSQDDLLLAESEGAFTIAEWDKVVSTGQKVCGQHREAELGSGMHEEGQDWNDMRQFIRTVMEARAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEL4</accession>
    <name>E3QEL4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_04464</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093340.1">
        <property type="nucleotide sequence ID" value="XM_008095149.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEL4"/>
    <dbReference type="GeneID" id="24409829"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04464"/>
    <dbReference type="HOGENOM" id="CLU_2739862_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ29320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="71" mass="7510" checksum="7065427AF68B0822" modified="2011-01-11" version="1">MLGSSRESRSLGAGTSAEADLGENAGLIVTYMNVLRHDPGTRQQVGRDYAAAGRGFLYGEIDVVPDVSIIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEX9</accession>
    <name>E3QEX9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Calcineurin-like phosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04579</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093455.1">
        <property type="nucleotide sequence ID" value="XM_008095264.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEX9"/>
    <dbReference type="GeneID" id="24409944"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04579"/>
    <dbReference type="eggNOG" id="ENOG502RZN8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060372_0_1_1"/>
    <dbReference type="OrthoDB" id="550558at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37844">
        <property type="entry name" value="SER/THR PROTEIN PHOSPHATASE SUPERFAMILY (AFU_ORTHOLOGUE AFUA_1G14840)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37844:SF2">
        <property type="entry name" value="SER_THR PROTEIN PHOSPHATASE SUPERFAMILY (AFU_ORTHOLOGUE AFUA_1G14840)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="266" mass="29891" checksum="27EF420EC1AAC301" modified="2011-01-11" version="1">MAIQIVSDLHLEAPKAYDIFEITPRAPYLGLLGDIGNIATHKDNCLSFLAQQLRQFRAVLFVPGNHEAYHSSWSETLEILRDFEERTKGDASLGEFVLLDRSSFRVPDSKVVILGCSLFSFIPPQSAGSVSMGLNDFFQINDWDVGMHNEAHTRDLAWLNAQVTELGHSDADIIIFSHWSPSRDGRAIDPRHAQSLITSGFATDLSGEVCYNSSNVKIWAFGHTHYNCDFEVEREGHAEPLRLVANQRGYYFAQATGYNRDKVIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEY7</accession>
    <name>E3QEY7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thioesterase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_04352</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093228.1">
        <property type="nucleotide sequence ID" value="XM_008095037.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEY7"/>
    <dbReference type="STRING" id="645133.E3QEY7"/>
    <dbReference type="GeneID" id="24409717"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04352"/>
    <dbReference type="eggNOG" id="KOG4781">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052827_0_1_1"/>
    <dbReference type="OrthoDB" id="506431at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03443">
        <property type="entry name" value="PaaI_thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052061">
        <property type="entry name" value="PTE-AB_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47260:SF7">
        <property type="entry name" value="THIOESTERASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G10800)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47260">
        <property type="entry name" value="UPF0644 PROTEIN PB2B4.06"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Thioesterase" evidence="2">
        <location>
            <begin position="189"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ29208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="292" mass="31638" checksum="3A0CB233A735C5AD" modified="2011-01-11" version="1">MTTPLVLSKRLLRPALTVQTHMMQSSGRCRQVCIRRFHPGVGADSVTQPMRTPSRFRRAIAFSAFGLLFAGLGFTAAASPLVPGLLDVTRHRSDEDSLRAYVPEDDGAKAIDDFINGHPLAAEMRQNPEMTESRPHMRLPDALRRHNLTGGTLLGPGRITVPPICWTEKGGKSLVSISHLGTDVCGHPGIVHGGLLATMLDEGLARCCFAALPHKVGVTAKLEINYRKPVHAGTYVVLRARTIRVEGRKAWVEGQLETLATEGEEPVVLAQASALFISPRFASIMAKLNATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGR7</accession>
    <name>E3QGR7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Alcohol dehydrogenase GroES-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_05199</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ30055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094075.1">
        <property type="nucleotide sequence ID" value="XM_008095884.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGR7"/>
    <dbReference type="STRING" id="645133.E3QGR7"/>
    <dbReference type="GeneID" id="24410564"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05199"/>
    <dbReference type="eggNOG" id="KOG0024">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_11_0_1"/>
    <dbReference type="OrthoDB" id="256333at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08234">
        <property type="entry name" value="threonine_DH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050129">
        <property type="entry name" value="Zn_alcohol_dh"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43401">
        <property type="entry name" value="L-THREONINE 3-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43401:SF2">
        <property type="entry name" value="L-THREONINE 3-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="6">
        <location>
            <begin position="34"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="5">
        <location>
            <begin position="179"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ30055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="355" mass="38663" checksum="799F82E67EF9CD1A" modified="2011-01-11" version="1">MANLSNLPKQMKALRYEKPEDWSIVQVPLPELRENDVLVKVRACGVCGTDLHIHEGEFIAKFPLIPGHETVGVVAAVGPKVKDFKVGDRVAADNSELCNECFYCRRGELLLCEHFEAHGVTMNGGFAEYCAYPAGKVFKINNLNDVDATLLEPASCACHGLDKIRPRLGSSVLMFGAGPTGLMLAQLMRHNGGCNVTIAAPQGLKMDLARSLDAADNYIELSRSDPEVQFSQLKSDNPYGFDVVVEATGSVKILEDAINYVRRGGKLVVYGVYNSSARVSWPPSKIFGDEITILGSFSETYMFPATIDYLDSGKVKTKGIVNKTFKLEQFGEALESIKNKSAIKAAIVFDDATGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGX5</accession>
    <name>E3QGX5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">General transcription and DNA repair factor IIH subunit TFB4</fullName>
            <shortName evidence="14">TFIIH subunit TFB4</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13 14">RNA polymerase II transcription factor B subunit 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">GLRG_05257</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 14">Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.</text>
    </comment>
    <comment type="subunit">
        <text evidence="14">Component of the 7-subunit TFIIH core complex composed of XPB/SSL2, XPD/RAD3, SSL1, TFB1, TFB2, TFB4 and TFB5, which is active in NER. The core complex associates with the 3-subunit CTD-kinase module TFIIK composed of CCL1, KIN28 and TFB3 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 14">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the TFB4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ30113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094133.1">
        <property type="nucleotide sequence ID" value="XM_008095942.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGX5"/>
    <dbReference type="STRING" id="645133.E3QGX5"/>
    <dbReference type="GeneID" id="24410622"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05257"/>
    <dbReference type="eggNOG" id="KOG2487">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040211_0_0_1"/>
    <dbReference type="OrthoDB" id="17307at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000439">
        <property type="term" value="C:transcription factor TFIIH core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.410:FF:000084">
        <property type="entry name" value="Transcription factor TFIIH subunit Tfb4, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004600">
        <property type="entry name" value="TFIIH_Tfb4/GTF2H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12831:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12831">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIH TFIIH , POLYPEPTIDE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03850">
        <property type="entry name" value="Tfb4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 14" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11 14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 14" id="KW-0804">Transcription</keyword>
    <keyword evidence="9 14" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="8 14" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="336"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00033341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU368090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EFQ30113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="365" mass="38752" checksum="4E9BD87892306839" modified="2011-01-11" version="1">MNAVDASDHYEVSSHEATPSLLSIVIDTNPRAWAALNDVLPLSKAIANILVFVNAHLAFSNANQVAIFASHSNRAVWLYPSKPEDAGANGAPYAEDVTMTDADFFAPTPNQSSANKFPQFAQIEAAVMSSMRKLVDATTEADLACTTTQLSGALTLALAHINKTSLSLNETNKAPDVARSTSSALSRLRARIFVLSVSDSEPVQYISTMNAVFAAAHSQIPIDTLALSGDATFLQQASYITDGTFMQAASPRGLLSYLMFAYSADAEARSSLIPPTHHTVDFRAACFCHGRVVDTGFVCSICLSIFCDVPDGSECLTCGTKLSLGSYGAKPAVIPRKKKKKKKTILANGHSREETGSAAGTPRPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>E3QI71</accession>
    <name>E3QI71_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Myb-like DNA-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_05830</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in pre-mRNA splicing and cell cycle control.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CEF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094706.1">
        <property type="nucleotide sequence ID" value="XM_008096515.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QI71"/>
    <dbReference type="STRING" id="645133.E3QI71"/>
    <dbReference type="GeneID" id="24411195"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05830"/>
    <dbReference type="eggNOG" id="KOG0050">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009082_0_0_1"/>
    <dbReference type="OrthoDB" id="1410009at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140602">
        <property type="term" value="C:nucleolar peripheral inclusion body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11659">
        <property type="entry name" value="SANT_CDC5_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000021">
        <property type="entry name" value="CDC5 cell division cycle 5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047242">
        <property type="entry name" value="CDC5L/Cef1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021786">
        <property type="entry name" value="Cdc5p/Cef1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047240">
        <property type="entry name" value="SANT_CDC5L_II"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45885">
        <property type="entry name" value="CELL DIVISION CYCLE 5-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45885:SF1">
        <property type="entry name" value="CELL DIVISION CYCLE 5-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11831">
        <property type="entry name" value="Myb_Cef"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="HTH myb-type" evidence="11">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="10">
        <location>
            <begin position="5"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="10">
        <location>
            <begin position="53"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="11">
        <location>
            <begin position="57"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="114"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="242"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="424"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="129"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="242"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00055157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ30686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="778" mass="86314" checksum="B6ACB57FE8900DE2" modified="2011-01-11" version="1">MGVVKGGVWTNIEDEILKASVSKYGLNQWARVSSLLARKTPKQCKARWNEWLDPSIKKTEWSKEEDEKLLHLAKLMPTQWRTIAPAVGRTANQCLERYQKLLDEAEAREAGQFGLTGIEGGEASAPSADDVRRLRPGEVDPDPESKPARPDTIDLDEDEKEMLSEARARLANTQGKKAKRKARERQQEESRRLAALQKRRELKTAGINIKVVTRKKGQMDYNADIPFEKKAAPGFYDTGEEQVRNEHQRQAFDPRKQQLASKRKGDGDDDGESKRRKKEKDAPSASFQAAVKAGQMQKIREAEQSSKRRALNLPAPQVSEGELEEIVKMGMMGERASMMARESENDATRGLVSEYSTLNNNAPIRTPRAPAQEDHIANEIRNIRALTNTQSSLLGGENTPLHEGSESTGFDGVAPRKQVVATPNPLATPMRANGVGQTPARAGQTPMRTPRDSFSLNADGSQALVSATPQDIKTRELALRSQLKQGLASLPKPKDSEWELELPEDQREAAAGEDMLIEDAGERDRREQEFRAAQEALEARRRTQVMQRQLPRPVKVDVSALLSTAETIQDTAQLLIAREAAALVANDAIKYPLPGSKVSGVPPRLDTIADDELAEARLQILSETRPKPSFAEIQASFEGRGKDSLLLGLGCYGDDEEEEEAAMKEAFDSMQDLIATTAEEGIKLEKTLGVYLGGYQKRQKMLKDKIGEAAEALEKANNALSGFKTLAISEEVAIQRRLGALRDEVGYVSRREREAQELYRKTRDELDALRANSVNGRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QI98</accession>
    <name>E3QI98_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Histidinol-phosphatase</fullName>
            <shortName evidence="8">HolPase</shortName>
            <ecNumber evidence="3 8">3.1.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_05857</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>L-histidinol phosphate + H2O = L-histidinol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14465"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="3.1.3.15"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 8/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the PHP hydrolase family. HisK subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.15" evidence="3 8"/>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094733.1">
        <property type="nucleotide sequence ID" value="XM_008096542.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QI98"/>
    <dbReference type="STRING" id="645133.E3QI98"/>
    <dbReference type="GeneID" id="24411222"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05857"/>
    <dbReference type="eggNOG" id="ENOG502RXUQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054611_0_1_1"/>
    <dbReference type="OrthoDB" id="5957391at2759"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00013"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004401">
        <property type="term" value="F:histidinol-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12110">
        <property type="entry name" value="PHP_HisPPase_Hisj_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000059">
        <property type="entry name" value="Histidinol-phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010140">
        <property type="entry name" value="Histidinol_P_phosphatase_HisJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01856">
        <property type="entry name" value="hisJ_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21039">
        <property type="entry name" value="HISTIDINOL PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21039:SF0">
        <property type="entry name" value="HISTIDINOL-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="PHP domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PHP" evidence="9">
        <location>
            <begin position="5"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049158"/>
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    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ30713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="310" mass="35176" checksum="D2621EE27A0B96EA" modified="2011-01-11" version="1">MAFTMHSHSGQFCPGHAKDQLEAIIQHAISIGYKTMGLTEHMPRLDITDLYPEELAEGDPEASIAVLAPRHEAYLVEAQRLREKYASQIDLLIGFEGEWYRPAYGPFIESLAAHPAVDYFIGSLHHVNAVPIDYSREMYVNAMKTAGGNEESMYERYYDQQHEMLTALRPRVVGHFDLVRLMSEDPGRDVRKWKSVWERIMRNLAVVKEYGGLLECNSSALRKGLDEPYPCRPIAEAWLEMGGRFTFSDDSHGIEQVATNYKRNLDYLESLGVTEVYTFERGPVEGVNGHAKAVLREKGVALGVFRTNFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIS8</accession>
    <name>E3QIS8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="13">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_05910</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094786.1">
        <property type="nucleotide sequence ID" value="XM_008096595.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QIS8"/>
    <dbReference type="GeneID" id="24411275"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05910"/>
    <dbReference type="eggNOG" id="KOG0054">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_27_6_1"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18596">
        <property type="entry name" value="ABC_6TM_VMR1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18604">
        <property type="entry name" value="ABC_6TM_VMR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000838">
        <property type="entry name" value="ABC multidrug transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000013">
        <property type="entry name" value="ABC transporter C family member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF356">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER ABC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="330"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="428"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="453"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="527"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="906"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="944"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1033"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="303"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="621"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="909"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1237"/>
            <end position="1492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="388"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1207"/>
            <end position="1232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="388"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="1207"/>
            <end position="1221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ30766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1508" mass="165969" checksum="EA1C8DA9751D9AD6" modified="2011-01-11" version="1">MDFFYERAFVLAATARSHSQTLLANIQSHGQLPWVDDVTEFTDSGYVQVLILVLSAVWTTSRLFRRRRARPLSSLPSRLYIRAAAIRWPWELAAQLSRAAALAFLALASARGQTPWLNALVVAYAFVLGLSRLVNDLQWRHVALYQVNFVVSAEVLILAASSVLPCIEASNECAIATPVRGGLVSLAVAVVVAITTPREWVPPSLIHDVPEEFAARGPAPEETCSWATYYLTFEWLTPLLWKGMRKDIVLDDLPQLPWYDEPLLLLERIKKARAKGVTTAWTLFYFLRSEVTLMACYISSAYACELIAPYGLYQLLAYLADPKGALIRPWLWLLLMFCGPLSRSVLFQQYVFTSTRLVVRLRSALTQELYHRAMGSMELEEDIFAPKEDSEKAQQKKDGKPGRSTTSAGRLANLMAADVQAIFGSRDIVMVSMGVSTGTIIAFVGLYKMLGWPALVGTAILFLAAPMSVIVAQMMARQTRKARRAQDSRISLVSEYLASIRAVKYFAWEDAIIKTIEETRANEQRDLWRVSLIYVALNQITALMPYISMIAMFTLYVGVCGQPLTAATAFTTTYLVKTIRRNVTQLGFMSRNITSAMIAIGRLDQYFNTTTPLEEYPEGALEIQDATFRRNKTASFQLRNISIGFVEGGVNVVSGASGSGKTTLLLAILGETIKESGTITRPKDVAFASQTAWLQNESIKDNILFNSAFEAVRYNNVVNACCLPVDLREMESGDQTVVGENGASLSGGQKARVALARALYSKAPLLLLDDIFSALDAKTAASLWERCFCSDLLKGRTVVLVAQQPWVAAQADVVVALENGAIKDVQQNIGVARHPVAVAKDIEGEITDVSDNSDTEVETQTDSLNDRGKVADDKGAKDAMTQEMNASGKSARLMFFKYMTYFGGPWYAIFCMFMMLISQLAVMGGSLWLSVWVEAYSKEVAVDIAFYLGIYAAFTVAESVLYAAVFLVFENGAWHAARKLHNDFIRAVMRVSLTWYKKTPVGRIINRFSSDMSSLDLTVSPQLRAFLESAISLVIRLFAISSIMPIFVIPAAVTCAIGIVVGEIYTRTAVTIKRLVASSQSPIFSQFADTLAGLAIIRARSGMPQMFGDALADKMRVWSRAAEANYNCNRWVAMRVDVVTALVGLSAGIIAVSKAGLVGAGLVGFSLQNATGLSQTILQLVRSMNDLEVELQSFVRIKEYAGLEAEEKADDSYPEEGEYTDDPSHTVPKTWPSTGEIEFRDVTIRYDEDGPNILTDVNLKFKAGERVAIVGRTGSGKSTLVLSLLRFTHIVSGQILYDGIDITKIPRRRLREALTIIPQEAVLFNGTLQSNLDPTGKIAAPVLERALESCQGIASFQYHSEVDADAAAAATAALEPDASGLALSTTVNAKGENFSHGQRQVLSLCRALVRGSRLMLLDEATASMDYETDKGIQEVLRREVDDDRTLVTIAHRLRTIADYDTVVVMGAGRVVEAGRPAELYKARGVFYDMVYHSGERRDLEVLFGDAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIZ1</accession>
    <name>E3QIZ1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">SNARE domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_05973</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094849.1">
        <property type="nucleotide sequence ID" value="XM_008096658.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIZ1"/>
    <dbReference type="STRING" id="645133.E3QIZ1"/>
    <dbReference type="GeneID" id="24411338"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05973"/>
    <dbReference type="eggNOG" id="KOG0810">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042423_0_2_1"/>
    <dbReference type="OrthoDB" id="10255013at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048278">
        <property type="term" value="P:vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15849">
        <property type="entry name" value="SNARE_Sso1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.70:FF:000008">
        <property type="entry name" value="Syntaxin family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF380">
        <property type="entry name" value="SYNTAXIN FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05739">
        <property type="entry name" value="SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="304"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="9">
        <location>
            <begin position="230"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="136"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="139"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ30829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="413" mass="45226" checksum="1CADC164520080AA" modified="2011-01-11" version="1">MAQYGYGDRQNPFDQRDGGSGGYGGPPQQAPYGGGNRYNNQGPTMGRDQYGANVEMESLAQNASGFGQSDPNAILNECRSIDQGIDQIESNLNQLRMLQERSLTDADTSANSSTARQLDALSSETMAMYRSLTDRVRTVKSSPDGQSARNSPQVGRVDRRLKGAIQQYQQVESAFRKRTQDQMARQYRIVRPDADEREVREAVEDAGAGAQIFQQAVMQSGRQAQANAVLNAVQDRQAALQKIEQQMVELAQLFQDMDVLVVQQEAAVTQIEQKGEEVVENLDKGNQEIGVAVETARKTRKKKWWCLGICILIIVIIAAIVAVYFAIIKPGQTAAAPAATKRAVAVRGLELPEISLTVPVDTGATSLHTFKTPSRVVRRIVQPGAGWEPNANAQEMSVADRFGRKVDMPAVQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIZ2</accession>
    <name>E3QIZ2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Memo-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05974</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MEMO1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094850.1">
        <property type="nucleotide sequence ID" value="XM_008096659.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIZ2"/>
    <dbReference type="STRING" id="645133.E3QIZ2"/>
    <dbReference type="GeneID" id="24411339"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05974"/>
    <dbReference type="eggNOG" id="KOG3086">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038085_0_0_1"/>
    <dbReference type="OrthoDB" id="417112at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07361">
        <property type="entry name" value="MEMO_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.830.10">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00055">
        <property type="entry name" value="MEMO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002737">
        <property type="entry name" value="MEMO1_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04336">
        <property type="entry name" value="AmmeMemoSam_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11060">
        <property type="entry name" value="PROTEIN MEMO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11060:SF0">
        <property type="entry name" value="PROTEIN MEMO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01875">
        <property type="entry name" value="Memo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="325" mass="36346" checksum="F82BD81C33B4A023" modified="2011-01-11" version="1">MAPRDTRPPGKQGEWYLGDADRLAKQLDEFLADVPDQIDGQGLPIPGARVIIAPHAGYSYSGATAAWAYKALDLSKAKRVFLLGPSHTYYLRGCAVTTYKKYGTPWGELRIDEETTDAIRRRDGVEDMPVRNEDREHSLEMHLPYLFKRLQQTFGSPDNFPTLVPILVGDNNKAEEKEVGKWLAEYLRDPDNAFIVSSDFCHWGSHFDYTVYCPDGDVTKMQKLRPHGSAPDGPPIHETVKLVDDLAIEAIKTGRHSAFYDNLKQTKNTVCGRHPIGVTMAALEELGGEGQEQQHRFRFIQYQRSSLVTGPGDSSVSYVSAYAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJ48</accession>
    <name>E3QJ48_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">MNNG and nitrosoguanidine resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_06030</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094906.1">
        <property type="nucleotide sequence ID" value="XM_008096715.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJ48"/>
    <dbReference type="STRING" id="645133.E3QJ48"/>
    <dbReference type="GeneID" id="24411395"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06030"/>
    <dbReference type="eggNOG" id="ENOG502QUA0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020178_1_0_1"/>
    <dbReference type="OrthoDB" id="2140105at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022703">
        <property type="entry name" value="DUF3533"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053001">
        <property type="entry name" value="MNNG_permease-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34814">
        <property type="entry name" value="NITROSOGUANIDINE RESISTANCE PROTEIN SNG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34814:SF1">
        <property type="entry name" value="NITROSOGUANIDINE RESISTANCE PROTEIN SNG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12051">
        <property type="entry name" value="DUF3533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="271"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="312"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="367"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="394"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="447"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3533" evidence="3">
        <location>
            <begin position="68"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="493"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="510"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ30886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="520" mass="58418" checksum="2DEFD2137F9247E0" modified="2011-01-11" version="1">MAILPQKEAAVSPTPANFDQTKENEQHNEEIGLGDRHQQPHHAVGFWHPLMRKVRAHVIRLWLRTIAILFLFILAVLSLYWAVLYRAEANLRSLIIHVVDFDGQVAPFESVQPIVGPTVLQIVQQSLNKPGPSLGWTVLPPSSFDNDPMAVRMAVYNWESWAAIIIHANATAALQDAVATGDANYNPAGSVQIIIQTARDQTTYQSNIQQYISQFTEEFAQQFGKLWGQIVMSNSSLSRDNLARASSAVNPGIAPLMIDLRPFQPATATPAVSIGLIYLIITAFFSFSFFLPIHSKYIQPQGHPPLRFWQLIVWRWLATTVAYFLISLGYSLISLAFQIPFSAPSASPIEPAPPAGATAYGRGTFPAYWMLNFVGMSALGLACENVAMIIGQPWTALWLIFWVITNVSTAFYAIDLSPGFYHWGYAWPLHHVVEGSRQLLFDLRSRIGLNFGVLFAWTAGNTLLFPLCCYFMRWKTENEKRNAERDKDRYVVETEDGEKELKKPEGTKPPIRRHGFMRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJ71</accession>
    <name>E3QJ71_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Thioredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_06053</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ30909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094929.1">
        <property type="nucleotide sequence ID" value="XM_008096738.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJ71"/>
    <dbReference type="STRING" id="645133.E3QJ71"/>
    <dbReference type="GeneID" id="24411418"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06053"/>
    <dbReference type="eggNOG" id="KOG0191">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021868_0_0_1"/>
    <dbReference type="OrthoDB" id="72053at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052250">
        <property type="entry name" value="PDI_TMX3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46426">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE TMX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46426:SF1">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE TMX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180499" evidence="7">
        <location>
            <begin position="23"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="673"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="8">
        <location>
            <begin position="14"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="8">
        <location>
            <begin position="249"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="166"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="169"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="240"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ30909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="728" mass="82920" checksum="3F4F33C23641D379" modified="2011-01-11" version="1">MRLSPLFLFLGSTLLSGVQVAAKEEQDHKASTYFNSMKVPPILELTPDTFDKEVKAHQFMLIKNYSPYCPHCIDYAPIFQTLYEFYYTSKPKSKDDKSFTDFYDFRFATVNCVAYFDLCAAHKIQSYPSTVLYKDGEVAEVIKGVKEIDQVSPIIEKYLEAAKPGTRPRNIELPKAGDKHSPDKAPGKTVDSKKPADNEVDEKTDAKAPSKEETKAPPKAPPAKEDTKPADKTDAKADAKASTTEKALATPTKPATKKPTATPNKDGISVPLTAEKFQTLVTMTQESWFVKFYAPWCHHCQAMAPNWQQMAKEMKGRLNVGEVNCDVETRLCKDARLRGYPTILFFKGGERVEYEGLRGLGDFLHYAEKAMDISEGVQEVDAESLAALEEKEEVIFIYFYDHATTSEDFMALERLPLSLIGKAKLVKTKDPVLYSRYKITTWPRLLVSREGRPTYYQPLTPKEMRDVHQVLNWMKSVWLPIIPELTASNAREIMDGKIVVLGIINREDSEGFMRARHELKSAANEWMDKQILLFQHERQELRDAKQLRIDEAEDRGDQRALRAAKATRINMDKSDRKQVAFAWVDSVFWQRWIRTTFGIDTKDGDRVIINDEDNRRYWDTTITGNNILLSRTSILETISKVVTSPPKIKPKLTISSFEKIFFDMRVTFVEHPYLTLGCILGLAFGAFSWFRSRSRRGRGGHFRLEESWGNKELMKEGLLGPSGNGKVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJE7</accession>
    <name>E3QJE7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">Chorismate mutase</fullName>
            <ecNumber evidence="4 13">5.4.99.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">GLRG_06129</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>chorismate = prephenate</text>
            <dbReference type="Rhea" id="RHEA:13897"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:29934"/>
            <dbReference type="EC" id="5.4.99.5"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:13898"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Metabolic intermediate biosynthesis; prephenate biosynthesis; prephenate from chorismate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="5.4.99.5" evidence="4 13"/>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ30985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095005.1">
        <property type="nucleotide sequence ID" value="XM_008096814.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJE7"/>
    <dbReference type="STRING" id="645133.E3QJE7"/>
    <dbReference type="GeneID" id="24411494"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06129"/>
    <dbReference type="eggNOG" id="KOG0795">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057757_0_0_1"/>
    <dbReference type="OrthoDB" id="191918at2759"/>
    <dbReference type="UniPathway" id="UPA00120">
        <property type="reaction ID" value="UER00203"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004106">
        <property type="term" value="F:chorismate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072545">
        <property type="term" value="F:L-tyrosine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120284">
        <property type="term" value="F:tryptophan binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046417">
        <property type="term" value="P:chorismate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009094">
        <property type="term" value="P:L-phenylalanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006571">
        <property type="term" value="P:tyrosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.590.10:FF:000002">
        <property type="entry name" value="Chorismate mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.590.10">
        <property type="entry name" value="Chorismate mutase, AroQ class superfamily, eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036263">
        <property type="entry name" value="Chorismate_II_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008238">
        <property type="entry name" value="Chorismate_mutase_AroQ_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037039">
        <property type="entry name" value="CM_AroQ_sf_eucaryotic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002701">
        <property type="entry name" value="CM_II_prokaryot"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01802">
        <property type="entry name" value="CM_pl-yst"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21145">
        <property type="entry name" value="CHORISMATE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21145:SF12">
        <property type="entry name" value="CHORISMATE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01817">
        <property type="entry name" value="CM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017318">
        <property type="entry name" value="Chor_mut_AroQ_eu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48600">
        <property type="entry name" value="Chorismate mutase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51169">
        <property type="entry name" value="CHORISMATE_MUT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8 13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 13" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-0584">Phenylalanine biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0827">Tyrosine biosynthesis</keyword>
    <feature type="domain" description="Chorismate mutase" evidence="14">
        <location>
            <begin position="146"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR017318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EFQ30985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="266" mass="30511" checksum="94C4F98EE0302A8C" modified="2011-01-11" version="1">MDSLIDLSDPSKALDLSRIRYQLIRLEDTITFHLIERAQFPRNQTIYVPGALDIPNSGLSFMDWYLREQEKLQSIIRRYDSPDEYPFFPEAVQKQILKPLHYPRILHPNDVNVNSKIKDFYVDKLLPALCPDFGHEDRGESQENYGSSATCDIACLQALSRRIHFGKFVAESKFRSDPEKYTKLIKAEDREGIADAITNAAVEKKVLERLRLKVLTYGTDPSIGAGPENQAKIDADAVVAMYEDFVIPLTKEVEVEYLMQRLEPVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJE8</accession>
    <name>E3QJE8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mitochondrial division protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_06130</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in mitochondrial fission. Acts as an adapter protein required to form mitochondrial fission complexes. Formation of these complexes is required to promote constriction and fission of the mitochondrial compartment at a late step in mitochondrial division.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the WD repeat MDV1/CAF4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ30986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095006.1">
        <property type="nucleotide sequence ID" value="XM_008096815.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJE8"/>
    <dbReference type="STRING" id="645133.E3QJE8"/>
    <dbReference type="GeneID" id="24411495"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06130"/>
    <dbReference type="eggNOG" id="KOG4155">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012350_1_1_1"/>
    <dbReference type="OrthoDB" id="496at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990234">
        <property type="term" value="C:transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd22881">
        <property type="entry name" value="Mdv1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000404">
        <property type="entry name" value="Mitochondrial division protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000881">
        <property type="entry name" value="Mitochondrial division protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847:SF637">
        <property type="entry name" value="WD REPEAT DOMAIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 11" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="319"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="361"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="438"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="521"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="544"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="214"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00043913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ30986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="662" mass="73517" checksum="20BB8C6D7825A6C5" modified="2011-01-11" version="1">MAASDNDQYGFHDDAGDDQSVLSTRGIEAFGRKVTTTASQLMAPLSDQGNTNHHHHYHGALAEVHKQLRRPTIQRSMFSMTKTTPTDMVRSKLSTTEIQHRALTYLPDELLANIPEGDNSYSLFQGFKASFPDLTEEGRKHRRRITRGRKMLEDAEHVPGTPQELQNLKKDKASMMHELEMLGVRKNMASSEIRDIDNKIANLHGMRRIILDRLANLEQDETLLEHDLMDVEARLEEAQDLVDEAESVAMNTPTKTEEDLAGDQDETGFMSQSVYEKLPTAAGTPAGTPASKAKKRVVRRKSMPILHEHFEAGTAIREIRAHQDTITALDFDAPFGTMVTSAMDDSIKVWDLNAGRCIGSLDGHTASVRALQVDDNFLATGGMDATIRLWDLSKAHYDPHGSQYGRDEDEDGIAFENPDDGPVEPPEGSMRDCHLYTLQSHVDEITALHFRNDTLVSGSADKTLRQWDLEKGRCVQTLDVMWAAAQASASLGSESSWRQTNRAPAQQADFIGALQVFETALACGTADGMVRLWDLRSGQVHRSLVGHTGPVTCLQFDDVHLVTGSMDRSIRIWDLRTGSIYDAYAYDNAVTSMMFDERRIVSAAGEDVVKVYDKVEGRQWDCGAGISEAEEGKTPAIVERVRVKDGYLVEGRQDGIVGVWTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKC3</accession>
    <name>E3QKC3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_06455</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697354">
        <property type="protein sequence ID" value="EFQ31311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095331.1">
        <property type="nucleotide sequence ID" value="XM_008097140.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKC3"/>
    <dbReference type="GeneID" id="24411820"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06455"/>
    <dbReference type="eggNOG" id="ENOG502REZE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_536358_0_0_1"/>
    <dbReference type="OrthoDB" id="4794487at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ31311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="590" mass="69582" checksum="2BE4529E89DC2593" modified="2011-01-11" version="1">MCIELWRRYFCPKAPHHTPTSDLNFGIDVHPQPREDVADHCLVQECDNVFRENEESPQDNVDEGRQIHWIYNLVRCAHLYSHECARSPCVGGRVQYFDHPCSYCSGGIDVHVRDYGEVLRDVSLPLRIPATGRAIDPEVVQRFEHYREKYLLRLLRLFHVMLLRSLPVRPEGETWKSFIETAWPETFCKLDFDHIGHGVVDCECPATKEEWRTNSAYSKRKNEALAILNGLEARSGPRGAYVYYWWTEGFGTDDDWEPTDRANGVYSKYDEETDFLPHQMQFVYFRQEDYDRRYTKLQTLARNCLRQLKERGKDISQEHPTTGYWQRCGIKWMGFDDWDRSLDRRMEFLEWVYQFLALDAGLHENVMMYLAAALLAMLNPWPNPQINYHPSHPNPYALDSELAAYDVLQECIWWVEYLWPLDGDLRVQDSYRESIDASSEVNWIIQRNRDIELLDMKSRNRTAAQKTGLFILPPEVAIAQGDEICPLCQERWGHFPFHEPVQLPCCNKFVGRRCMKQFLASKPIRPAGGDYMRREKWVEEFRCALCREGVGHHFSPHFYGQLLGDPPRDIRDLSFYDDYEGFPRPSEYWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLQ7</accession>
    <name>E3QLQ7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_06770</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697357">
        <property type="protein sequence ID" value="EFQ31795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095815.1">
        <property type="nucleotide sequence ID" value="XM_008097624.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLQ7"/>
    <dbReference type="STRING" id="645133.E3QLQ7"/>
    <dbReference type="GeneID" id="24412135"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06770"/>
    <dbReference type="eggNOG" id="ENOG502S9CJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014758_0_0_1"/>
    <dbReference type="OrthoDB" id="5407653at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="384"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="532" mass="58763" checksum="1D946D8826EBCF53" modified="2011-01-11" version="1">MFGTYPALANLPTGVKVDPKDVPPPTPVTLPQSRPQLHAPLAPAGQTKPLTSVLQSVYRPGDVTSAVFNALGVHLIPDVPPADLIPDSACLPDFEGWDQLSPDEASEKNAETRNLLNNGVQSPGCQTYLDRKRELSHSNEDAFRTVRRIPAPKGQQQARLGNSYEFFRCLEAFTPYWDDTSNPAKPHGETDGDKTVVDTDKSERANPSTPAYQRVIRSSAGSSMPGECRQSLLTAFLKLVAYDFGCNVSAPRTEPRLHITAAPPPSQPSKHQVEPQAPRSSYFASGCIFIFRTPRTREAARQGVVEGPLAAVSARATISFESKNDQDIDLARELVAALVTAQHRAREGKTEKRFGDGAWWTTKPRWGGGPGGPIGREVERDAIQGDKDNVNAGTGQPASKRPRKNMSIYDNYRMVRPPSASWDHKTRYEAIGKVKGAGYDDIYVISSLFHHISILRVRVPERLLEVLEGADEGGVHRSWGQLEARRSPWYDFFVLEQRLDAMKLVWSLMAWLMRKEETTAEKTGEDVKMTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLW9</accession>
    <name>E3QLW9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Subtilase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_07001</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095877.1">
        <property type="nucleotide sequence ID" value="XM_008097686.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLW9"/>
    <dbReference type="STRING" id="645133.E3QLW9"/>
    <dbReference type="GeneID" id="24412366"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07001"/>
    <dbReference type="eggNOG" id="KOG1153">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011263_1_4_1"/>
    <dbReference type="OrthoDB" id="206201at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000007">
        <property type="entry name" value="Subtilisin-like serine protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF11">
        <property type="entry name" value="CEREVISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180555" evidence="7">
        <location>
            <begin position="18"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="8">
        <location>
            <begin position="168"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ31857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="423" mass="43644" checksum="6CDD0DC8CFB8009C" modified="2011-01-11" version="1">MVRPIAILAAVLPAVLAAPFGLNENKAANNTDTFMGVPISNLNALDLIPNKYIVVYNNSFDDDAITSKMSSFAAAIKKRNIGKRSLDGRSLSTSTRNFKMNNWRATVMEADDNMIMNVMSAEEVAYVEQDAKVKISATVSQTNAPPGLVRLSHAAAGETGYVFDQVSGDGITAYVVDTGILTTHSEFQGRATFGANFINNVDTDENGHGSHVAGTIGGQTFGVAKNVKLVAVKVLDGDGAGSNSGVLDGMQFVIDDVKAKNITGKAVMNMSLGGSASAAVNRAIEALNTAGIVPVVAAGNENQDAANTSPASAPNAITVGAIDARNDRKASFSNFGKVVDIFAPGVNILSVGIASNTATNTLSGTSMASPHVAGLAAYLMGLEGLNTVKSLTDRMLQLATASGASVQRNTAGTTNLIANNGQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>E3QM28</accession>
    <name>E3QM28_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="18">ABC-2 type transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">GLRG_07060</name>
    </gene>
    <organism evidence="19">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095936.1">
        <property type="nucleotide sequence ID" value="XM_008097745.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QM28"/>
    <dbReference type="STRING" id="645133.E3QM28"/>
    <dbReference type="GeneID" id="24412425"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07060"/>
    <dbReference type="eggNOG" id="KOG0061">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_57_1_1"/>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03213">
        <property type="entry name" value="ABCG_EPDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000702">
        <property type="entry name" value="ABC transporter (Adp1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050352">
        <property type="entry name" value="ABCG_transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041:SF2">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="12" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 15" id="KW-0732">Signal</keyword>
    <keyword evidence="4 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179858" evidence="15">
        <location>
            <begin position="24"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="316"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="825"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="858"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="902"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="938"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="968"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1057"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="16">
        <location>
            <begin position="80"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="17">
        <location>
            <begin position="369"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="652"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="652"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="681"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EFQ31916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1080" mass="118256" checksum="75952DAD3778FB1A" modified="2011-01-11" version="1">MAPPALRSLLIGALACFPALASAQRNYSTADMLRTQLTLLDGRPSDCPPCFNCLLPAHKCTQFAGCNDFTGKCNCPEGFGGDDCLDPLCGSLSRGDNTDRPRRTGDSCECDDGWTGINCNVCTSNQACDALMETKEGGVCYQNGEVINHNYQICDVTNKKITDLLGKQRPQVTFTCKKEEGNCDFQFWVDERESFYCHLNDCSSTADINESQNSTDYKCNKIECNCISDRMLCGENGSVDISDFLVEEIKGPAEFQCLQKNGGINNCAFREPAMDDLILSLIGDSSIQLSCRSGECLYHTQVPGYERPVKKINTPLIASVIAACSLFVVAVILITWYLSRRKFKYGAIVLDDSDDESLKLMADHKPASLYFENVAYHLNGKRILNNIQGMAHPGEVTAIMGASGAGKTTFLDILARKNKRGQVSGDFYVNGEKVTDTDYKNVIGFVDQEDTMLPTLTVHETILTSALLRLPRNMGRTAKEQRVFEVEKQLGIYHIRDSLIGSEEGKGRGISGGEKRRVGIACELVTSPSILFLDEPTSGLDAYNAFNVIECLVTLAKNYKRTVVFTIHQPRSNIVALFDRLILLARGSAVYSGPFSQCQGYFDHIGYSCPPGFNIADYLVDLTMHAGSTVSEDDGALNADVASLRPSSTTAVKSIPSISGGSINEDSGVESSSSRPKNKRRDSVKIRQERELFTRRKNNADTAASSDAGGEDTGSYKLQNQPGFVPSLNVEDPHDLPPSAYVGTDLDILIRSFAESDIAGSTHDEIQQSIAAAEGANGQNANGYTPEGPNIHISAIGKGYARVGYTRQFVILSQRTWKNLYRNPILMLTHYAIAILLAVLSGYLFYGLTDDIPGFQNRLGLFFFLLALFGFSTLTSLTVFATERLLFVRERANGYYSPITYFAAKILFDIIPLRIIPPILMGAIIYPMTGLVPDAGHFFKFILVLVLFNFAAAAICLFIGIVCKDGGVANLIGSLVMLFSLLFAGLLLNHNAIPKAALWLQTLSIFHYGFESLIVNEVLQLTLVDKKYGLDITVPGAAILSSFGFNNDALWTDVINLGIFGVVFIILAYGAMHFLLVEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QM50</accession>
    <name>E3QM50_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07082</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095958.1">
        <property type="nucleotide sequence ID" value="XM_008097767.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QM50"/>
    <dbReference type="STRING" id="645133.E3QM50"/>
    <dbReference type="GeneID" id="24412447"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07082"/>
    <dbReference type="eggNOG" id="ENOG502QW6Q">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027502_2_0_1"/>
    <dbReference type="OrthoDB" id="6431331at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37471:SF1">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37471">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="533" mass="61156" checksum="AFB538CBF4455D36" modified="2011-01-11" version="1">MLNRTFHEWVFIRTCIILMRYPLIPYVSILTACYLGMNHSQSPARWRTIAQVIFGMMLIELLYILFIWLPYTRRLKEPAKHPPPSSPIERRALFERCMATVPNYGDYLRMWFLGSEQSEIRRENMREFLLWAFFDVEYGSNSGAGSADDYDVEVDEYISYIEKGLGKTFEPGRGRAKCLRLTIDSVEPAFRTVWWYATMALLDHATHILLLLNGFEYYAQPREKAIFPPRLQQIFASRRTLAGNLSYWYRPHRSEELPVVFLHGIGIGLWPYINFLAEIVGTKGKGQTGVIVPEILPVCFRLTEPPLGKEVFLDQFKKILDHHMWDKFALVSHSYGSILSTHAIKSPELQARIQRAVFVDPVSILLHLPDVAYNFTRRRPTTANEWQLWYFASTDPGVAHCLGRYFFWRENAIWANELVGELGHVRDERKEARQVTVCLSGLDLIVDSHAVASYLAGSDRANHPAWLLSEHGQSNVAGLKAGLTPGGDYEQHRSVELGVNILWFPNKDHAQVFDSPRTRAPIVAAIRGESPTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QME5</accession>
    <name>E3QME5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07177</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096053.1">
        <property type="nucleotide sequence ID" value="XM_008097862.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QME5"/>
    <dbReference type="STRING" id="645133.E3QME5"/>
    <dbReference type="GeneID" id="24412542"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07177"/>
    <dbReference type="eggNOG" id="ENOG502SPP7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027441_2_0_1"/>
    <dbReference type="OrthoDB" id="2603at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="261"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="300"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="325"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="357" mass="38560" checksum="C50B57505A439D30" modified="2011-01-11" version="1">MNASANLRKSYIRTSVLIPIPPTGPILEDSTLKRRTLKSEVPEVDDAQRHQIVQALNYLEYQTRCTIERHDSLSYPIKEYSLENSAVEVQGSPSTQASRMLTIYPIKDMNWVVTMLFVVGSLIFVINGVLGLLPFIDPALAFPALANILLPGTILTGAVMFLTGGTLGVFAAFNADRGTLEKTEGKSIEDGANVIYRPALIGSPAWVWIPSAADAAAVLKTLPFQAGLVQLLGGVIFTVPAVAGVPGLLDPNDLPVFSMLVFVPQVIGGSLFFLANFALIIFAQDVWYKPKFGSCEWQGAYWNTLGSAGFAITGVLLLQGNFSGASVMSFAASSAYLIGSIFQWYVLMEFHATPWAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMH4</accession>
    <name>E3QMH4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosomal RNA methyltransferase FtsJ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07206</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096082.1">
        <property type="nucleotide sequence ID" value="XM_008097891.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMH4"/>
    <dbReference type="STRING" id="645133.E3QMH4"/>
    <dbReference type="GeneID" id="24412571"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07206"/>
    <dbReference type="eggNOG" id="ENOG502S5H8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043071_0_0_1"/>
    <dbReference type="OrthoDB" id="417125at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002877">
        <property type="entry name" value="RNA_MeTrfase_FtsJ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01728">
        <property type="entry name" value="FtsJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal RNA methyltransferase FtsJ" evidence="1">
        <location>
            <begin position="81"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="338" mass="38412" checksum="F157322D32F426C7" modified="2011-01-11" version="1">MFERSGDIIVEFLRTNVPEFARLSAGWENPAGDTYFRKQRQAADSADEKLSAIFYNMMKDIGVELHRKLYAFTIKGPPLGQKRILDMCMAPGGFLAIALQKNPGAHALGFSLPVSQGGFQRLLSPSKNVEVKFMDITMLVQDMGATDIPSNHPDSDHFIRQQQLGPQDKFHLVLCDGQVLRQHQEFRAQYRERCEARRLTATQLALGLEHLEPGGTMVVLLHKVEAWDTVLLLWKFSKFSTVRLFKPTKRHVNRSSFYMVASKVQSLSAAATAAIKVWKEVWRVATFDLNGEMKHNWREEEPSAKELIDEFGDQLIRLGKHIWKTQADALEKAAFIRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMK3</accession>
    <name>E3QMK3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07235</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096111.1">
        <property type="nucleotide sequence ID" value="XM_008097920.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMK3"/>
    <dbReference type="STRING" id="645133.E3QMK3"/>
    <dbReference type="GeneID" id="24412600"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07235"/>
    <dbReference type="eggNOG" id="ENOG502S6YK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_148782_1_1_1"/>
    <dbReference type="OrthoDB" id="2100988at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34286">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34286:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="98" mass="11025" checksum="705DF731CBAC5EAA" modified="2011-01-11" version="1">MGGGPKVPYPKHVWSPAGGWYAQPANWKRNTAVIGAVMAGVVAVIWKISAEKEVRYVMPQEGRFFPSRYWSKQLIEYDREQAARKAKDTTQAEAVQNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMT6</accession>
    <name>E3QMT6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Non-classical export protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07318</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697360">
        <property type="protein sequence ID" value="EFQ32174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096194.1">
        <property type="nucleotide sequence ID" value="XM_008098003.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMT6"/>
    <dbReference type="GeneID" id="24412683"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07318"/>
    <dbReference type="eggNOG" id="ENOG502SD8V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_202020_0_0_1"/>
    <dbReference type="OrthoDB" id="2155101at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024242">
        <property type="entry name" value="NCE101"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11654">
        <property type="entry name" value="NCE101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="59" mass="6191" checksum="46E254F784982881" modified="2011-01-11" version="1">MAAPPAYIISKVADPIFALVIGLGAAATRINREEKEKGKTTQQTIAAAKRRLGLVKATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMU4</accession>
    <name>E3QMU4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">T-complex protein 1 subunit gamma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_07326</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697360">
        <property type="protein sequence ID" value="EFQ32182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096202.1">
        <property type="nucleotide sequence ID" value="XM_008098011.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMU4"/>
    <dbReference type="STRING" id="645133.E3QMU4"/>
    <dbReference type="GeneID" id="24412691"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07326"/>
    <dbReference type="eggNOG" id="KOG0364">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008891_7_3_1"/>
    <dbReference type="OrthoDB" id="10248520at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd03337">
        <property type="entry name" value="TCP1_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000037">
        <property type="entry name" value="T-complex protein 1 subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.260.10:FF:000023">
        <property type="entry name" value="T-complex protein 1 subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000005">
        <property type="entry name" value="T-complex protein 1 subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012719">
        <property type="entry name" value="Chap_CCT_gamma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053374">
        <property type="entry name" value="TCP-1_chaperonin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054827">
        <property type="entry name" value="thermosome_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02344">
        <property type="entry name" value="chap_CCT_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041082">
        <property type="entry name" value="thermosome_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041083">
        <property type="entry name" value="thermosome_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ32182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="539" mass="59201" checksum="01C86C6D14900D0A" modified="2011-01-11" version="1">MQAPVVVMNTQSGERQTGRKAQLSNIAAAKTVADIIRSCLGPKAMLKMLLDPMGGIVLTNDGHAILREIEVSHPAAKSMIELSRTQDEEVGDGTTTVIILAGEMLAQSLPQLERNIHPVQIIAAFRRALKDALEIVDDISLPIDVNDDKAMRGLISSSIGTKFVSRWSDLMCDLALRAVRTVTWEAGNGKTEVDIKRYARVEKVPGGEIEDSRVLDGVMLNKDITHPKMRRRIENPRIVLLDCPLEYKKGESQTNIEISKEEDWNRILQIEEEQVKSMCEAILALKPDLVITEKGVSDLAQHYFMKANVTALRRVRKTDNNRIARATGATIVNRVDDLQDSDVGTLCGLFEIEKIGDEYFTFLTKCKNPKACTVLLRGPSKDVLNEIERNLQDAMGVARNVMFNPRLSPGGGATEMAVSVRLSQLAKGVEGVQQWPYKAVADALEVIPRTLVQNAGASPVRVLTDLRAKHAEGKHSWGINGDSGVVADMKEYGVWEPEAIKLQSIKTAIESACLLLRVDDICSARKAAQMGNGLHGGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>E3QN06</accession>
    <name>E3QN06_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">6-phosphofructo-2-kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_07388</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697360">
        <property type="protein sequence ID" value="EFQ32244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096264.1">
        <property type="nucleotide sequence ID" value="XM_008098073.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QN06"/>
    <dbReference type="STRING" id="645133.E3QN06"/>
    <dbReference type="GeneID" id="24412753"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07388"/>
    <dbReference type="eggNOG" id="KOG0234">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006383_3_1_1"/>
    <dbReference type="OrthoDB" id="267323at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003873">
        <property type="term" value="F:6-phosphofructo-2-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006003">
        <property type="term" value="P:fructose 2,6-bisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006000">
        <property type="term" value="P:fructose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003094">
        <property type="entry name" value="6Pfruct_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013079">
        <property type="entry name" value="6Phosfructo_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606:SF32">
        <property type="entry name" value="6-PHOSPHOFRUCTO-2-KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606">
        <property type="entry name" value="6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01591">
        <property type="entry name" value="6PF2K"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000709">
        <property type="entry name" value="6PFK_2-Ptase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00991">
        <property type="entry name" value="6PFRUCTKNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="6-phosphofructo-2-kinase" evidence="4">
        <location>
            <begin position="130"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="6-phosphofructo-2-kinase" evidence="4">
        <location>
            <begin position="232"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="74"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ32244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="652" mass="73325" checksum="AF280D55F05B51B5" modified="2011-01-11" version="1">MSSNKDFRPHASSPPFHANKSTSPSFPNGEPLPMPVSHPHDGLLPPPAMAHVIRSMNDLNGPIALRDRSLIASSDTPPAMRSVVSTAPSSPRIPPVRQNSGGTTPRLRPHPATLNVPGMTVSRASPDGKISDRDVAAKLVIIMVGLPARGKSYITKKVQRYLSWQQYNSRIFNVGNRRRVVAGLTSPIKSAHSPATFRLDPPAQAASILLNGHMSQANKEPAELNLNDSSDAMDQSAKFFEPTNESAAKLREQVALDTLDELLDYLLHQGGSVGILDATNSTIERRQLLVDRIKAREPKLGILFIESICHDQNLLEANMRLKLSGPDYKDKDPHQSLADFKRRVAAYESAYVPIGAYEEANDMQYIQMIDVGRKLIQHRLRGFLSGGISSYLTTFNLAPRQIWLTRHGQSVDNRLGKLGGDSELTPDGERYGSALHAFVTQKRKEWLIEQKDKIAQSSFPPKAGDHTPPYPELNRELEEKNFCVWTSMLKRSVQTATEFENDDDYDVKNWAMLNELNAGLFEGLTYEEIARRFPGEYRKRAEDKLHYTYPGVGGEGYLQVIARLRDMVREIERIEDHVLIIAHRSVCRVLMAYFMDLTRNEIADLDVPLGMLYSIEPKPYGYDFHAYRYHADKGNFFEIPNYRLQRTVDRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNM3</accession>
    <name>E3QNM3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription initiation factor IIB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">General transcription factor TFIIB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">GLRG_07780</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Associates with TFIID-IIA (DA complex) to form TFIID-IIA-IIB (DAB-complex) which is then recognized by polymerase II.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFIIB family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697362">
        <property type="protein sequence ID" value="EFQ32510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096530.1">
        <property type="nucleotide sequence ID" value="XM_008098339.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNM3"/>
    <dbReference type="STRING" id="645133.E3QNM3"/>
    <dbReference type="GeneID" id="24413145"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07780"/>
    <dbReference type="eggNOG" id="KOG1597">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043736_1_0_1"/>
    <dbReference type="OrthoDB" id="25790at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097550">
        <property type="term" value="C:transcription preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001139">
        <property type="term" value="F:RNA polymerase II complex recruiting activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001113">
        <property type="term" value="P:transcription open complex formation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001174">
        <property type="term" value="P:transcriptional start site selection at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd20551">
        <property type="entry name" value="CYCLIN_TFIIB_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000008">
        <property type="entry name" value="Transcription initiation factor IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000141">
        <property type="entry name" value="Transcription initiation factor IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.170:FF:000001">
        <property type="entry name" value="Transcription initiation factor IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.10:FF:000036">
        <property type="entry name" value="Transcription initiation factor IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000812">
        <property type="entry name" value="TFIIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023486">
        <property type="entry name" value="TFIIB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013150">
        <property type="entry name" value="TFIIB_cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013137">
        <property type="entry name" value="Znf_TFIIB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618:SF13">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00382">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08271">
        <property type="entry name" value="Zn_Ribbon_TF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00685">
        <property type="entry name" value="TIFACTORIIB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00782">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51134">
        <property type="entry name" value="ZF_TFIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIB-type" evidence="15">
        <location>
            <begin position="24"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00056616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00066213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EFQ32510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="351" mass="38433" checksum="3DC1CC59BA19C8D5" modified="2011-01-11" version="1">MLGPNGAATDENGNSEGFRDDLNMVVMCPDCKEYPPHLVEEFSSGDMVCGSCGLVVGERIIDTRSEWRTFANDDQGNDDPSRVGDAVNPLLNGSQLETTIAFGDGRDSKQLARLQNKSQNDKASKSLMQAYKEIGAFCDSINLGKNVSDAAKHIFKLTYDHNFMKGKPQEAVIAGCIFIACRQTGVGRTFREIFQVTHVSKKEIGRVFKQLESFLQKIKEENPRGAGSLSNLDGYKASASTSAEDLCTRFCSNLNFRNAQKIENVSRALARKTSSVSELAGRSPLSVAAACIYMASHLMKEVRTSKEIASVAGVSDGTIKTAYRFLYQARDRLIEKEWGADKKAIDGLPVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNQ6</accession>
    <name>E3QNQ6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cellulosome enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_07683</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697362">
        <property type="protein sequence ID" value="EFQ32413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096433.1">
        <property type="nucleotide sequence ID" value="XM_008098242.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNQ6"/>
    <dbReference type="STRING" id="645133.E3QNQ6"/>
    <dbReference type="GeneID" id="24413048"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07683"/>
    <dbReference type="eggNOG" id="KOG2566">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031530_1_0_1"/>
    <dbReference type="OrthoDB" id="2012278at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039514">
        <property type="entry name" value="6GAL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039743">
        <property type="entry name" value="6GAL/EXGAL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033452">
        <property type="entry name" value="GH30_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42767">
        <property type="entry name" value="ENDO-BETA-1,6-GALACTANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42767:SF1">
        <property type="entry name" value="ENDO-BETA-1,6-GALACTANASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14587">
        <property type="entry name" value="Glyco_hydr_30_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17189">
        <property type="entry name" value="Glyco_hydro_30C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180622" evidence="1">
        <location>
            <begin position="21"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="Endo-beta-1,6-galactanase-like" evidence="2">
        <location>
            <begin position="22"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 30 beta sandwich" evidence="3">
        <location>
            <begin position="368"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ32413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="477" mass="50052" checksum="AAD36C44D58A7760" modified="2011-01-11" version="1">MVGLAALAAAMGCLVTLSSGQVTVDAGTTLQPIDGFGFSQAFGRAKEFQNAPQALQKQALDLLFNTTSGAGFSIIRNRIGSGGRGDSILPVSPGSPTGQPAYVWDGDDGGQVWFTKQAVSYGVEQIYADAWSAPGFMKTSGNEATAGYLCGTTGHTCASGDWRQAYANLLAQYIKYYAQTGLNVTHVGFLNEPDYSPSYSQMQISFNAQEAISFIPTLHQTLQSAGLTTKITCCDAVGWGSTVKYTNALVPAGMEQYLGLITSHTYSGDADSALNTSLSSWVTESGITKAFDTTWYNNGGPTEGMTWANKIAVGIVNARLSAYLYWEGFELNQLQSDSHLVDTRDGATATPSANFWAFAMWSRYIRPGAMRLATSGTVSGVLTAAVRNTDGSVVLVLTNNGAAAQSASVSFNGGFVPGAAAAYVTDNTRTFAVTQVAVSGPAVSVSVPAKGVVTVKLGSASTRTNSTVLYTRGPRHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNR6</accession>
    <name>E3QNR6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_07693</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697362">
        <property type="protein sequence ID" value="EFQ32423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096443.1">
        <property type="nucleotide sequence ID" value="XM_008098252.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNR6"/>
    <dbReference type="GeneID" id="24413058"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07693"/>
    <dbReference type="eggNOG" id="ENOG502QPK1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_46_1_1"/>
    <dbReference type="OrthoDB" id="5296287at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046943">
        <property type="term" value="F:carboxylic acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17316">
        <property type="entry name" value="MFS_SV2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000395">
        <property type="entry name" value="Carboxylic acid transporter protein homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000465">
        <property type="entry name" value="Carboxylic acid transporter protein homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23508:SF9">
        <property type="entry name" value="CARBOXYLIC ACID TRANSPORT PROTEIN (AFU_ORTHOLOGUE AFUA_2G09450)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23508">
        <property type="entry name" value="CARBOXYLIC ACID TRANSPORTER PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="316"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="347"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="443"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="70"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="487"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="487"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ32423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="514" mass="55931" checksum="FD3436C8AEF79E89" modified="2011-01-11" version="1">MSTPTAQPADPIAKGVLATAKQSLKDLFIWKQRTVVVTPDGETLTEWQDPDPIKNPISLMAQLSPRDWLFFICGFCAWTADAFDFHALSIQTTKLAKYYDRSKTDITTAITLTLLLRSIGAAAFGLAGDKYGRKWPMVANMIILGLLQIATIYSTTFQQFLAVRSLFGLFMGGVYGNAIAMALEHCPSNARGLMSGILQQGYSFGYVLAACANLGVGGGVETWKTVFWIAAGISIAVGLVRIVFPESQQFLEAKARGKKTASPGAFWRETKKMLAQEWKMCVYCIILMTWFNYYSHTSQDSYTTFMIAQKEMDNSGASRASILMKAGACVGGTIIGYLSQFFGRRRAIIASALMSACLIPAWILPQGERALSASGFFMQFFVQGAWGVIPIHLNELSPPAFRSSFPGITYQLGNMISSPSAQIVNAIAEKTFVRAPSGHSVEAYGPVMGIATAIIAMGIVITTMFGPERRGRSFEHAVAGVQGEVAETKEMDDHDEEKGSIRAATVENAAPHKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QP11</accession>
    <name>E3QP11_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07613</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697363">
        <property type="protein sequence ID" value="EFQ32599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096619.1">
        <property type="nucleotide sequence ID" value="XM_008098428.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QP11"/>
    <dbReference type="STRING" id="645133.E3QP11"/>
    <dbReference type="GeneID" id="24412978"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07613"/>
    <dbReference type="eggNOG" id="ENOG502T39X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032832_0_0_1"/>
    <dbReference type="OrthoDB" id="2520703at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056867">
        <property type="entry name" value="LRR_15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24969">
        <property type="entry name" value="LRR_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Leucine-rich repeat" evidence="1">
        <location>
            <begin position="148"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="490" mass="55841" checksum="BCDAE218508C3520" modified="2011-01-11" version="1">MTAGSRAARALSFLELPVEVQTHILQQLAYLHHQSIRAVLLTCKHLHQLALPLSVYTYENVTSKNMSQHAQKRSRNLDFLRYITITKPELAHNVRRISIIHVSTSLIYRLAPTNKRPLGPTSDEMAVYTDLIDASGLSSHIENWEAVRDEWLRGLVDGLVEQQIGLLLLACPRLETLKLGTPLSPRLLPRLIRAAARHAMISTSGAPPGTNRPLLDSLRQYFGEPESPKTLFHFFNIGKEFLQLPQLRSFTCLSLSNSGPNGHLFNEEASPPGCSNVQDMTLLDTNVTIEGLRSLIWACRGLKSFHWTPGDSSFSDMQIKLPDLAQALLPHRETLQHLYIDYQDRWREMDWYRKRENFFIGTFLKDMTSMKTLHIGMEAFMGFTDLCTIGHEQSSVPEEERLTEINKTSRLVSYIPPSLQFLELHGCTLDIVPHVQHLLNLLQTEETFASMRKIRLRFSADHIDARALGFTFDAKRVDFGYSFRFHSSNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3QP52</accession>
    <name>E3QP52_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ABM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_07654</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697363">
        <property type="protein sequence ID" value="EFQ32640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096660.1">
        <property type="nucleotide sequence ID" value="XM_008098469.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QP52"/>
    <dbReference type="STRING" id="645133.E3QP52"/>
    <dbReference type="GeneID" id="24413019"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07654"/>
    <dbReference type="eggNOG" id="ENOG502TE0W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112102_0_0_1"/>
    <dbReference type="OrthoDB" id="3830579at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ32640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="157" mass="16946" checksum="9B15A4ED815146A7" modified="2011-01-11" version="1">MASWASLESRAAFGKSPQHQQAVEALKPVLAGPIPAKCPRFDLDTSTFVPPPPQVINSPICEVITVRHCSGNAEEMATKLKKAETLPGCFAAHSGIGASNTPDQGTIWLGFIGWRDYESSKDADKSVYMPHGVGDMEVHHINFNFPIKGFSVTNPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QP67</accession>
    <name>E3QP67_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_07799</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697364">
        <property type="protein sequence ID" value="EFQ32655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096675.1">
        <property type="nucleotide sequence ID" value="XM_008098484.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QP67"/>
    <dbReference type="STRING" id="645133.E3QP67"/>
    <dbReference type="GeneID" id="24413164"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07799"/>
    <dbReference type="eggNOG" id="KOG4730">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1348821_0_0_1"/>
    <dbReference type="OrthoDB" id="371463at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ32655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="203" mass="22852" checksum="9D153F2F2CFAF16A" modified="2011-01-11" version="1">MAIGAHRSSLREDSMVAAGVPSIDIVDGWLAALTSLGLLGVILRMKFSIYPDFKVYAQQEEVRERLGLRPLFHYLSPARRARFLRGGWVAADMPTQDHNLAKVPIDEFPCRPHLSKNMREVLTQSAKNIDPDVSPHCRPRSDFVVLLTQFFKRIYLNGISKSVVGEAIVVYQGIDTKRDVVKAATREGLVYFLLLHVHNSPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3QP87</accession>
    <name>E3QP87_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoribosylaminoimidazole-succinocarboxamide synthase</fullName>
            <ecNumber evidence="3">6.3.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">SAICAR synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_07819</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SAICAR synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.6" evidence="3"/>
    <dbReference type="EMBL" id="GG697364">
        <property type="protein sequence ID" value="EFQ32675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096695.1">
        <property type="nucleotide sequence ID" value="XM_008098504.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QP87"/>
    <dbReference type="STRING" id="645133.E3QP87"/>
    <dbReference type="GeneID" id="24413184"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07819"/>
    <dbReference type="eggNOG" id="KOG2835">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045637_0_2_1"/>
    <dbReference type="OrthoDB" id="9991235at2759"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00131"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004639">
        <property type="term" value="F:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046084">
        <property type="term" value="P:adenine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd01414">
        <property type="entry name" value="SAICAR_synt_Sc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000015">
        <property type="entry name" value="Phosphoribosylaminoimidazole-succinocarboxamide synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00137">
        <property type="entry name" value="SAICAR_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028923">
        <property type="entry name" value="SAICAR_synt/ADE2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001636">
        <property type="entry name" value="SAICAR_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018236">
        <property type="entry name" value="SAICAR_synthetase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010568">
        <property type="entry name" value="PRK13961.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00081">
        <property type="entry name" value="purC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43700">
        <property type="entry name" value="PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43700:SF1">
        <property type="entry name" value="PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01259">
        <property type="entry name" value="SAICAR_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01057">
        <property type="entry name" value="SAICAR_SYNTHETASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01058">
        <property type="entry name" value="SAICAR_SYNTHETASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAICAR synthetase/ADE2 N-terminal" evidence="10">
        <location>
            <begin position="17"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ32675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="308" mass="33748" checksum="907E34D1DC110971" modified="2011-01-11" version="1">MAAASVTSVDLTGLKKIGQGKVRDVFEVDDKTLLFVASDRVSAFDVVMKNGIPDKGAILTHASAHWFKVLSDRVPGLKTHFLTLDPPAGLPAADAALIKNRSMQVRRLKVIPLEAIVRGYITGSAWSEYKAKGTVHGIRVPEGMQQSQAFETPLYTPSTKAEQGEHDENIHPDEAARIVGDAALAKRVEELALALYSAARDYARERGIILADTKFEFGVDPATGDVVLVDEVLTPDSSRYWPAEGYAVGRDQESFDKQFIRNWLIEHGLKGKEGVELPEDVCRATADKYKDVFLKLVGKSFDDVVAQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPD3</accession>
    <name>E3QPD3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Clr5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07865</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697364">
        <property type="protein sequence ID" value="EFQ32721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096741.1">
        <property type="nucleotide sequence ID" value="XM_008098550.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPD3"/>
    <dbReference type="STRING" id="645133.E3QPD3"/>
    <dbReference type="GeneID" id="24413230"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07865"/>
    <dbReference type="HOGENOM" id="CLU_2426890_0_0_1"/>
    <dbReference type="OrthoDB" id="5308957at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025676">
        <property type="entry name" value="Clr5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788:SF3">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14420">
        <property type="entry name" value="Clr5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Clr5" evidence="1">
        <location>
            <begin position="20"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="91" mass="10803" checksum="A439F59B12D93BDA" modified="2011-01-11" version="1">MDISYDISVPLIIGKPFATDDIWNCHRSIITRLYRDKNKSLKQVKQIMERDYNLFATERMFKTRIKSWGLDKKFKEAESCTYFGSSRNGTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQ05</accession>
    <name>E3QQ05_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_08087</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697366">
        <property type="protein sequence ID" value="EFQ32943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096963.1">
        <property type="nucleotide sequence ID" value="XM_008098772.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQ05"/>
    <dbReference type="STRING" id="645133.E3QQ05"/>
    <dbReference type="GeneID" id="24413452"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08087"/>
    <dbReference type="eggNOG" id="KOG0737">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004223_0_0_1"/>
    <dbReference type="OrthoDB" id="39734at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051701">
        <property type="entry name" value="Mito_OM_Translocase_MSP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45644:SF56">
        <property type="entry name" value="AAA ATPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12920)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45644">
        <property type="entry name" value="AAA ATPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12920)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="766"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="26"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="669"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="68"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ32943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1041" mass="115349" checksum="3E9E348B62AF0273" modified="2011-01-11" version="1">MHATGLRALASASRVSASSRLALTIARQSQCRQFHPSYRLRKSPSEGGAGAEDGKPSEKPAGEQQDDGGSRSRDDGINKTEVNSSESAFRRSRGGAFASARARLARPRPADELPPVKLPTSFLENGVSLYDPKNRIDTLTNDLWHRRYMGTRWHDLLWKDLELVFNHASWTEAKLQDALRQGNLEAIERRNRILAETSQWLSLSIDEMRSSNHPQGSREPLPTTEFADMLRYSNKFVLSNLLSQHTRGTTDAGPVEDQNQDSVLQSLVDQYIQEGRPKPRRDGLRLFDPRIRGEIVTAVLAELSLRPDAGSVGRELKRPLTVVNIPNYSGRSHTKKLIEHVASCAEADLVHLDAQELAMLVGDYIGQDCAYSRGSMSVLGYRAAEMNGRLAKTEESPKPNDEDLSGEIEAAWVNLRDHGVDGGYNSPMDNELQKIREGPKDYILPSVDRWENLKINAVLEEIVNSPTKMTSQSDRNLIIHVDDFVELNMTLEGALLIGRLRAIVDTMWRAGKKVILVGTSSNENPSDQYTSTLKEIAAEECLIPLPLNFQRIVNASNTKKMYEASDYLQENLRNIQHMLRAIAGVSPDMSKLRIVGVSTSSPPQYLLGDAEGTFKEASQIPRVLTTSILPVSDVYHIARLFFVCEGSASPNQEWRTLFDVVESSSYSTAQMHRLQDRPTSSKPSAGGGNSASADMQKTEPERLRVSGNYNDYEKKLLSGLVNSSEIKTTFADVHADPETKNNLKLLTSLSLVRPEAFTYGVLATDRIPGCLLYGPPGTGKTLLAKAVAKESSANMLEVSGASINDMYVGQSEKNVRALFSLAKKLSPLVIFIDEADALLAARGQRNRAAHRETINQFLREWDGMSDTKAFIMVATNRPFDLDDAVLRRLPRKILVDLPLQPDRASILRILLKGEDLDPSVSVDDIARKTVLYSGSDLKNLCVAAAMTAVQEESEEAARHTGPAPYVFPPKRTLRQDHFDKALKMIAASVSEDMDSLKSIRRFDEKYGDVRVRNSQKKRGMGFGVLPTSADAEEARVRQAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQ60</accession>
    <name>E3QQ60_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Adhesin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_08142</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697366">
        <property type="protein sequence ID" value="EFQ32998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097018.1">
        <property type="nucleotide sequence ID" value="XM_008098827.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQ60"/>
    <dbReference type="STRING" id="645133.E3QQ60"/>
    <dbReference type="GeneID" id="24413507"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08142"/>
    <dbReference type="eggNOG" id="ENOG502S7KB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019703_0_0_1"/>
    <dbReference type="OrthoDB" id="3539644at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="286"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="744"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="218"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ32998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="846" mass="91304" checksum="34C6620D38E9C8C8" modified="2011-01-11" version="1">MPAPYSDDLYSADDSDYDDHVTDDNDLDHHLSPTDGYFQNSTSTSSDGGIYPPQQEHFHSQDDVTDATFPTSAGVPHVPNILVQDPSLRLQQEGSSTTSQKDREAREEARLNSPPVGRTSSSPATPTDDHHYYDGSSTAADSEATPSHTTAATTTAYTYTSSNAAQSSSSSYTPYAPSVDAPLRTPQTHPSRSLYSQPASLFRIPREAPPAYTPSPTSPLASSPTPSRNYQTFSSNMGAREEEARLLGRDPESMGDDSYDSHDPRPSPSWKDRVLKKFSRRTVKTALLVALVFFTLTGFLSMLATAVVSVPSDKPPSTEPPKELDPVTGQPIKVGPSEPTQPSEPNSPVPWNPSRTCLQSEYRFDPKVFGVSFNPDKTLSIIQAVESDAPSRGYRPQVTGDLVVRRLQGSAPGPSVELEVVANHDGLDVGVDWDSELQRLLIKVPQRIDWTSSLRPCLAVRATLWVPENAELSHLYLGTTHLGVELADDLSVTIKNGFEIVAISGDVHTPVEPSSTYRLGSRDIAVKTISGDITGSWPLYDSLKIRSESGDIHANVNPQPVLESAPRPAVLEVTSISGTISIKEPLDQAASSTKPDAVIPPRDYVTTLDAKSGGIRAWVAFTTLALAESISGDVAVELLPVFNISLLQSLGEPELHTSTKSGNVAIKMLEPIWVEIASTEGTPGGEKPRAKPDEPIDIPTNPLPVPNIPKIPRVPSAPFIPGIGQPFRRSPLWAGKWTDAWPVRRSSADASTQTEERDIMANDQPPMRLKSSHSTISGTMEIHYPASWEGSVRAESNSGKINIRGKGVTIDSRTTWPRAVHAHKGQPLSSSASLSSISGDQTLLIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQI7</accession>
    <name>E3QQI7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08269</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697367">
        <property type="protein sequence ID" value="EFQ33125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097145.1">
        <property type="nucleotide sequence ID" value="XM_008098954.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQI7"/>
    <dbReference type="STRING" id="645133.E3QQI7"/>
    <dbReference type="GeneID" id="24413634"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08269"/>
    <dbReference type="eggNOG" id="KOG2793">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030437_1_0_1"/>
    <dbReference type="OrthoDB" id="433955at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF147">
        <property type="entry name" value="S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE OF THE SEVEN BETA-STRAND FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ33125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="406" mass="44013" checksum="066BD4568D070E63" modified="2011-01-11" version="1">MRPVAHPLPPSSSLPPLRTLDRLSEADITSALHSLSMIYCSLPVSVAFQLTPETQKPAHHDTSLADSGYVSETEDDHEEIDGLDHHVAALKVDAFERSFAERWLTGFIARAETLYCFESDEACQHALDQASCVLESFFAVPKDDDDQNGQNQDYARKFAFDLVLPGSDTLRASVPVTVRLNDRLAGTNSADPDDVGLQSWGASILFSEIMCASPACFGLAQPGLGPSPRVIELGAGTGLVSLVLGGMLPHLGATSPTIVATDYHPAVLENLRSNVLLNFPASEVKHMQTAALDWSAPVLEAPLDVPADIIIATDVIYAPEHAVWLRDCAARLLATNGVFWLMVTVRRNGRFNGVSDSVEAAFMETHDPARADGKRLTIVQSEELEKRTGVGRGDESGYKLLEIRWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQM8</accession>
    <name>E3QQM8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glucoamylase</fullName>
            <ecNumber evidence="9">3.2.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">1,4-alpha-D-glucan glucohydrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Glucan 1,4-alpha-glucosidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_08310</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>Hydrolysis of terminal (1-&gt;4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glycosyl hydrolase 15 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.3" evidence="9"/>
    <dbReference type="EMBL" id="GG697368">
        <property type="protein sequence ID" value="EFQ33166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097186.1">
        <property type="nucleotide sequence ID" value="XM_008098995.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQM8"/>
    <dbReference type="STRING" id="645133.E3QQM8"/>
    <dbReference type="GeneID" id="24413675"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08310"/>
    <dbReference type="eggNOG" id="ENOG502QPM2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012173_1_0_1"/>
    <dbReference type="OrthoDB" id="6123450at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004339">
        <property type="term" value="F:glucan 1,4-alpha-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001070">
        <property type="term" value="F:starch binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.10:FF:000018">
        <property type="entry name" value="Glucoamylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013784">
        <property type="entry name" value="Carb-bd-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002044">
        <property type="entry name" value="CBM20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011613">
        <property type="entry name" value="GH15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000165">
        <property type="entry name" value="Glucoamylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046966">
        <property type="entry name" value="Glucoamylase_active_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008291">
        <property type="entry name" value="Glucoamylase_SBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31616:SF12">
        <property type="entry name" value="GLUCOAMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31616">
        <property type="entry name" value="TREHALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00686">
        <property type="entry name" value="CBM_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00723">
        <property type="entry name" value="Glyco_hydro_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001031">
        <property type="entry name" value="Glu-a-glcsd_SBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00736">
        <property type="entry name" value="GLHYDRLASE15"/>
    </dbReference>
    <dbReference type="SMART" id="SM01065">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49452">
        <property type="entry name" value="Starch-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51166">
        <property type="entry name" value="CBM20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00820">
        <property type="entry name" value="GLUCOAMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180714" description="Glucoamylase" evidence="12">
        <location>
            <begin position="20"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="domain" description="CBM20" evidence="13">
        <location>
            <begin position="496"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="199"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR001031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001031-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001031-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ33166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="612" mass="66546" checksum="69958468BC1529A3" modified="2011-01-11" version="1">MALRSSLLWFAGLVANVAAADVDAFISQQRDIALKGALNNIGPNGSQVQGASAGIVVASPSKNDPDYFYTWTRDAALTMKVIVDEFIFGRKELQVYLEDYYRSQAVLQTITNPSGSFLPSGRGLGEAKYTVDGSRFNGAWGRPQRDGPALRAITLITYSRWLAENGEQAKAKNVIWPIIANDLSYTGQYWNSTGFDLWEEVSGSSFFTTQNQYRALAEGAALAQSLGVKCTGCELAPDVLCFLQTFWNSNDGYYTANINTQTERSGKDANVMLGSIAVFDVTASCEDPSIQPCHSQSLSNFKVWVDSFRNASLYPINKGIAPNKGIALGRYSEDVYFDGNPWYLITIGAAEFLYDVVAQWNAQGQIKVDATSRPFFADLYPPVKEGTYQRSSNISGAYASITGAVKAYADSFIEIAQKYTPANGSLAEQFNKITGTPLSARDLTWSYASFVTMAERRAGLYPSSWVPASSEVPAACAATSVTGLYVPAIAAGAPNVTGSCTIAVSFLVNATTYYGEELYVLGNIADLGSWNVENAQPMTASGYTAERPLWNVDVELPGGQNITYLYVRRQNCNQGYIYEERNRTLAVPPCNSTQNLVVDDTWTGRQGTSGSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QR58</accession>
    <name>E3QR58_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cleavage and polyadenylation specificity factor subunit 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08490</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697369">
        <property type="protein sequence ID" value="EFQ33346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097366.1">
        <property type="nucleotide sequence ID" value="XM_008099175.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QR58"/>
    <dbReference type="STRING" id="645133.E3QR58"/>
    <dbReference type="GeneID" id="24413855"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08490"/>
    <dbReference type="eggNOG" id="KOG1689">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068704_0_0_1"/>
    <dbReference type="OrthoDB" id="277288at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005849">
        <property type="term" value="C:mRNA cleavage factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18871">
        <property type="entry name" value="NUDIX_Cfim25_Nudt21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.79.10:FF:000005">
        <property type="entry name" value="Cleavage and polyadenylation specificity factor subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016706">
        <property type="entry name" value="Cleav_polyA_spec_factor_su5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13047">
        <property type="entry name" value="PRE-MRNA CLEAVAGE FACTOR IM, 25KD SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13869">
        <property type="entry name" value="NUDIX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ33346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="269" mass="30470" checksum="D4EA406591633E0D" modified="2011-01-11" version="1">MSTITTTALQSGHAPIIPLAFNSNQPETIRLYPLSNYTFGVKETQPEEDPSVIARLKRLEEHYNQHGMRRTCEGILVCHEHNHPHILMLQIANAFFKLPGDYLRPEDDEVEGFKSRLDERLAPVGRIGEGEEPADWQVGDCLAQWWRPNFETFMYPFVPAHVTRPKECKKLYFIQLPKSKVLSVPKNMKLLAVPLFELYDNTARYGPQLSAIPHLLSRYNFEFVDENGNIVAATPGSSAPEGYVPTTKILASGDDTDMQEAKEDDNGEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRI0</accession>
    <name>E3QRI0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peroxin 20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08747</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697371">
        <property type="protein sequence ID" value="EFQ33468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097488.1">
        <property type="nucleotide sequence ID" value="XM_008099297.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRI0"/>
    <dbReference type="STRING" id="645133.E3QRI0"/>
    <dbReference type="GeneID" id="24414112"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08747"/>
    <dbReference type="eggNOG" id="ENOG502S3XI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042939_0_0_1"/>
    <dbReference type="OrthoDB" id="5407351at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="106"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ33468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="400" mass="42991" checksum="F44B6855C109D0BE" modified="2011-01-11" version="1">MSDSSCGGSTPFKSLVEHGSHDRSLHQDRFVDAPRVQQGFRSAGSVPPAQAQANFGTFLGSNSTAQIDSVKLSTYVTPITRSFQALQTPKMPDTQHVYRLSPDPNRSSVSRVSSAAGGAAMHTPHRQNYAASSPTATPTWAQDFTRFVGGVSNAGSLPSGSLATQYRPLIPPAFAHNMMPPQAGPSISRPVAGSAVSNMASAEADFDLEMGQWVATHGDGRMEQVDAVMEQIARELAQQEEQQSSTAGHLFSIDLTASMDTATISPPSVSLENTTEHTRTNLVAETINQQANDGQSLFDTRNAAVPSNMNHLEQVPDMSQLNLHEASESAAPRPVEHAQSQTEISEAARQILQSVQHENGDKWKNSQFLLLMKDFRDGNKDIVNNEILETSAGGERIAGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRX0</accession>
    <name>E3QRX0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Daunorubicin C-13 ketoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_08538</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697372">
        <property type="protein sequence ID" value="EFQ33609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097629.1">
        <property type="nucleotide sequence ID" value="XM_008099438.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRX0"/>
    <dbReference type="STRING" id="645133.E3QRX0"/>
    <dbReference type="GeneID" id="24413903"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08538"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_44_6_1"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF282">
        <property type="entry name" value="WW DOMAIN-CONTAINING OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ33609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="340" mass="37853" checksum="7DA46C24F80F1CE3" modified="2011-01-11" version="1">MPNSWDQPLANMPPLQGKVAVVTGSNAGVGLSTVKFLALRGATVYFTTRTKDKADATRARLTSEYPEIDQDQLRWLSLDLANLKTVVAAVTELKSKEKKVDILINNAGAVSSTTDTLGPGWEYHMAVNHVGHFVFTNGILPLLKEATRQKEADVRIVTLASSVNYTFLPSNYRFTFDSPSFLKSPLSSYPWQWRYVLRHFLFVDMIRYAVSKVANILFAQELQRLMDEQGLPILSISVHPGGVASEGNLDIGNSVFSLLRSTFFLSTDQGAATSLFAATAREVRENPEKFKGKYLEPFGKVVTPNPVFKDTEQVRGLWDNTTTEVNRYLAEIGLAPLQQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSC5</accession>
    <name>E3QSC5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_08896</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697373">
        <property type="protein sequence ID" value="EFQ33752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097772.1">
        <property type="nucleotide sequence ID" value="XM_008099581.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSC5"/>
    <dbReference type="STRING" id="645133.E3QSC5"/>
    <dbReference type="GeneID" id="24414261"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08896"/>
    <dbReference type="eggNOG" id="ENOG502S073">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024655_2_0_1"/>
    <dbReference type="OrthoDB" id="4216928at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="17"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="47"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ33752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="426" mass="47193" checksum="37AD9563E1A7ECCE" modified="2011-01-11" version="1">MSNSFLERANPPPRRKTCLACTKAKRRCDHGQAACLRCSRRNIDCVYPTPPPTSRSKRQTAPKLIETPAPQEDLESLTETPATCPDNSLAPWQQDADLLQLDMDGLDGIGLYTDFHDFLAPDVLIDGPSSLSSPTSSPEQMLLPSQDLAADGSLEEMISSRLQYALDEMKNVPASIVLENQAPWSHPYLYRAHMPREMQDAQACCALYIAKNPSNSRFVLRTIQARAHELLSSPTPRDRLSILARLQAALLYQIIRLFDGDISLRASAQQALPALDGAMLALTPFVKWERGRPETGPAEDRPACPTKETWQEWIFQESARRTMFFTSFLLAAYNVLVGKMTVDCQGSHFIGLSWTLSAHLWGAPDVVAFAVAWGEKRHFVVTREGFGNVLKDAGADDVDAFGRILIVGAVGIDEARLWFHNRGGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSF6</accession>
    <name>E3QSF6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_08927</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697373">
        <property type="protein sequence ID" value="EFQ33783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097803.1">
        <property type="nucleotide sequence ID" value="XM_008099612.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSF6"/>
    <dbReference type="GeneID" id="24414292"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08927"/>
    <dbReference type="HOGENOM" id="CLU_1875277_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="108"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="93"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ33783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="136" mass="15133" checksum="2F4F6E4C65614CB5" modified="2011-01-11" version="1">MSSDSDDSDSDNSDSDNSDSDDFDAGQTAIVATSQENSKSSATSLCHTKAKELPRVTGNDLQKRKRQAEDDSEQDVGKDGTGQEDTVRKETQEIDDDDGDDLDDQIQLAEMQLALRQAEMRLAILRQRKKRKQSKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSU4</accession>
    <name>E3QSU4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glucose-methanol-choline oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_09076</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="GG697375">
        <property type="protein sequence ID" value="EFQ33932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097952.1">
        <property type="nucleotide sequence ID" value="XM_008099761.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QSU4"/>
    <dbReference type="GeneID" id="24414441"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09076"/>
    <dbReference type="eggNOG" id="ENOG502QSPJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002483_0_0_1"/>
    <dbReference type="OrthoDB" id="9974421at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052542">
        <property type="entry name" value="Cholesterol_Oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47470">
        <property type="entry name" value="CHOLESTEROL OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47470:SF1">
        <property type="entry name" value="FAD-DEPENDENT OXIDOREDUCTASE 2 FAD BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="84"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="18"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="36"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ33932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1293" mass="142210" checksum="E2F501BBBFC2A65B" modified="2011-01-11" version="1">MAEYNGEVNGNGQTKTSGANGANGEANGYRGAPRTYQDSFETPYGGSTTEPYEGYDKSDGMFDPVTGTYPRISRPVELIRPSYDAVVIGSGYGGAVAASRMARGNKKVCLLERGKEKWPGEFPSNILQAMGELHSSNATTDGIMGRLGKYGTQGDPTGLYHLIVGDGQNAFVGNGLGGTSLLNANVFLEADNGVLDLPIWPDKLRGAENFRKYYERAADVLEPERYPKDFPKLHKLETLEKQANLMGWGDKFYRVPQTTRFEDGENSTGVYMRASTLSGQDTTGLNDGSKSTTLVNYLSDAWNWGAEMFCQCEVRYVTEAPKERGGYIVHFAWHGGKRANFKGIFHEDLMWVHAKELVFFGAGSIGTTEILLRSKKFGLNMSEDVGHGMSGNGDILAFGYNTSEYINGMGRPDPPPNRPVGPCITGVIDCRHGLDNPLDGFVIEEGAIPAALAPFYQRMLTLLPGKVFPHNISIKGAIDHVAAAAGSRVFGPYYPKGSTEKTQCYLIMSHDSSQATMQLHNDRPMINYSGVGKSHRAKKLAGYLAKLTNLIGGTYVDSPFYAAFGEKEITVHAIGGARISADGTGASGGVNDKGQLFVDNTDKVHKGLVVCDGTIVPAALGVNPFATITALAERSVEMVAEEFGIEINLEEKNGSLNLFAEPAHNQFEGDDDSLQVAKVKEIIKTARDDKTPGIAFSEMMDGWIHFGSDSKSLDFERATETARSRGEYARFFLSARSWNTHNLVNDKEHEANLTGTFTCPALGGTCMVQGGKFQLFNDDPRSPDTMNLTYNFLVSQKDGKKLHFNGYKVVNSDVVFNPWNLWKATTTLYCTITEVDEHDQSIPSEVRGKGVIHIRPSAFLQECTTMEATGSSLYAKVTSTANFLGYFTAKAASAFLTPFIPQMWPSLPFHSYENPTPWSEECTVVANDRVRTKLYMWEPQGNGGQQSDNAPIVLFIPGAAVDHQIFALPTIKENAVKYFREKGYRVYSMVHRVGKTVVAQQNWTTYDARRDIHAALKEIRKRHTIIDKMDGSGPSHMTYVVAHCAGSVALASGLLDGTIPRQWLSGVTASQVFMNPRFAKVNTMKASLPISMANIYNLVQGKWFDCSSTPNDGYIQQALNQVLRFYPVGHRNEICNSVVCHRSSLVFGRLWSHKGLNEATHSQLENFLGGTSMASLNHLMYQGTHGIATDSQNENLVTPQNIARLKGLDIFFFSGTENDVYAPDNTDTSFTTLSEANGGVCYERQVFPDRGHLDAWMSPTAHKDVFPRVLHHIKKVETKNHHHQELKKVAGQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTS3</accession>
    <name>E3QTS3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Mitochondrial carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_09379</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697378">
        <property type="protein sequence ID" value="EFQ34235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098255.1">
        <property type="nucleotide sequence ID" value="XM_008100064.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTS3"/>
    <dbReference type="STRING" id="645133.E3QTS3"/>
    <dbReference type="GeneID" id="24414744"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09379"/>
    <dbReference type="eggNOG" id="ENOG502QU7F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043560_0_0_1"/>
    <dbReference type="OrthoDB" id="409948at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47567">
        <property type="entry name" value="MITOCHONDRIAL SUBSTRATE/SOLUTE CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47567:SF1">
        <property type="entry name" value="NAD-DEPENDENT EPIMERASE_DEHYDRATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="200"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="33"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ34235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="375" mass="41400" checksum="0BCD377F537FD371" modified="2011-01-11" version="1">MAAQRDLESQRKTSDERTPLLGTSAGDEANQQHARDRGDDDDRSGEHEDVEQVPLIASQDGEGENKRTTGWWLWRAFWVVLAVFFLTIFIKGWIDAKDTNFDLKAALKRALGGGLSGAAAMVLQVLTLMPIRTIMNYQYRFGTGFQEAVSTLYQDGGVRRYYQGIGAALIQGPVSRFGDTAANAGILALLESNSFLNQLPTLIKTIFASLCAAAFRMILTPIDTLKTTLQAQGSKGTAILRKRIKTHGVGSLWWGAFATAAATFVGHYPWFGTYNYLSANIPEPEKGHLFLWLLRLAFIGFCASIISDSVSNSLRVVKTYRQVNDTQVSYSKAAKLVIQRDGFVGFLGRGLKTRILANGLQGILFSILWKLFLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QU77</accession>
    <name>E3QU77_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09559</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697380">
        <property type="protein sequence ID" value="EFQ34415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098435.1">
        <property type="nucleotide sequence ID" value="XM_008100244.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QU77"/>
    <dbReference type="STRING" id="645133.E3QU77"/>
    <dbReference type="GeneID" id="24414924"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09559"/>
    <dbReference type="eggNOG" id="ENOG502SNRP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103066_0_0_1"/>
    <dbReference type="OrthoDB" id="4124983at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053146">
        <property type="entry name" value="QDO-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36440">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_8G07350)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36440:SF1">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_8G07350)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin type-2" evidence="1">
        <location>
            <begin position="45"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="126" mass="14061" checksum="0C440D3A2F17DAC2" modified="2011-01-11" version="1">MPLRGPVPVKLYKKEDSEKISVGPMTIYIFEDGSNTDNRIGCMTLELPPATSGPPMHWHRFHDECFFVTKGTVRFKTPDGDVDAQEGQLMVVPPRAIHTFANPSETEPAEFFMTSTPDCGRGPLHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUA3</accession>
    <name>E3QUA3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_09585</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697380">
        <property type="protein sequence ID" value="EFQ34441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098461.1">
        <property type="nucleotide sequence ID" value="XM_008100270.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUA3"/>
    <dbReference type="GeneID" id="24414950"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09585"/>
    <dbReference type="eggNOG" id="ENOG502T4K3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2263541_0_0_1"/>
    <dbReference type="OrthoDB" id="4804717at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ34441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="112" mass="11773" checksum="512F13CE9F7E7DC3" modified="2011-01-11" version="1">MSAATAGIASRTFAAPLPRAAFSTAPSRAATGAGPAPGKNNSVSDMKNNRPGEGTVEIPVFSLRHITTSPRARFWLMAGFCVLGGVEVYGWYTFGPKVLGWGEGRKGGKNFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUQ2</accession>
    <name>E3QUQ2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_09734</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697381">
        <property type="protein sequence ID" value="EFQ34590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098610.1">
        <property type="nucleotide sequence ID" value="XM_008100419.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUQ2"/>
    <dbReference type="STRING" id="645133.E3QUQ2"/>
    <dbReference type="GeneID" id="24415099"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09734"/>
    <dbReference type="HOGENOM" id="CLU_1626913_0_0_1"/>
    <dbReference type="OrthoDB" id="10252740at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ34590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="163" mass="17861" checksum="C2C7D511E6ECA26C" modified="2011-01-11" version="1">MQFANNVTSPIFAGRWDLRGKKLWVPNRQPLQSWSLLILENACNEATDQAVAPSFKLLSSILHYTTTPPSNLTPNSYQCLLGAANAFSTPNRVSFMVKVVVITMGAVFRAGVFGIWIEDACTSRGAIFGASSLTGKYLIARIDKNRGQICASDDELRSLMNKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUQ8</accession>
    <name>E3QUQ8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_09740</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697381">
        <property type="protein sequence ID" value="EFQ34596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098616.1">
        <property type="nucleotide sequence ID" value="XM_008100425.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUQ8"/>
    <dbReference type="STRING" id="645133.E3QUQ8"/>
    <dbReference type="GeneID" id="24415105"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09740"/>
    <dbReference type="eggNOG" id="ENOG502T47T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_900186_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12087">
        <property type="entry name" value="TM_EGFR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="225"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="202"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ34596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="309" mass="31381" checksum="3656BFAD5B9FEDFD" modified="2011-01-11" version="1">MSALTSTVPNGQLVAVSNTLTLAILVFNRGLLDDILSNPGKIVSDILSSPATTTQNNEQPANTPAAAQTQTAAAAVPAATTPAAEAPVATTQAPVAKQPAATPAASPKQEQPQEIHTSLPPALVLPSTQQPAPSTSAAPLTTAAKSASRDEVLTTSPPVAAETVPPKAENAASSQVPLQPAVNSKTGAASIEGAVTTKTEATSPTQPSQTLTPGGTSNSTNQGPLVATGVVLGIVVFLGLSLLLFWCLRRKKKADRHDHTAVPSTSPVNEHGDVWIPSAAADPTAVSDPDLPMADSLVSQWSVHAERLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUW2</accession>
    <name>E3QUW2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RGS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09794</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697382">
        <property type="protein sequence ID" value="EFQ34650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098670.1">
        <property type="nucleotide sequence ID" value="XM_008100479.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUW2"/>
    <dbReference type="STRING" id="645133.E3QUW2"/>
    <dbReference type="GeneID" id="24415159"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09794"/>
    <dbReference type="eggNOG" id="ENOG502SG2M">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041181_0_0_1"/>
    <dbReference type="OrthoDB" id="3232309at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39466">
        <property type="entry name" value="RGS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39466:SF1">
        <property type="entry name" value="RGS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="302"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="345"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="418"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="451" mass="51246" checksum="0B4A379EFEA1A1EB" modified="2011-01-11" version="1">MEASKERNTRREEANVELQMTKPSRFNFPDWLVWYKKPEYRDFREYATAIRNGRRPMSRDGRDKTQIPARLSLEKVLANETCSPMSLYDFYMYLKYIEFSPENLEFFVWFRNYEASYARTGSLNNYPIAEKDASQSSSSRNSVNDAAAEVAGIKLPSINMSEFDCDPEAANETMTNIVNLIAPETACQPNSRIGPTGRDRIKSWANGCARPVSNVATIPARIAPNSAYRAELNAIVKNFLLPDSEKELNIPPALRDQALLDLQHSSDPVHLKPIAEHVYGLLKNCSHRNFVRLGVSNGTFETLCMATSVGIVLTIAGFLCVFLRAFVPFTGAHSRWNAFAPWPMWFVGMSLILSGLRGSCFFLLLFTRRQPLPWERFDDSASLLSQRTGLMKFISRMMIFDRKIRVKDTHLRKLQHKIVLQAMAGGAMFASLSVLLFVLLPVWRETAKLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVU1</accession>
    <name>E3QVU1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10123</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697386">
        <property type="protein sequence ID" value="EFQ34979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098999.1">
        <property type="nucleotide sequence ID" value="XM_008100808.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVU1"/>
    <dbReference type="STRING" id="645133.E3QVU1"/>
    <dbReference type="GeneID" id="24415488"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10123"/>
    <dbReference type="eggNOG" id="ENOG502SPKB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1094191_0_0_1"/>
    <dbReference type="OrthoDB" id="1896086at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="254" mass="28185" checksum="94DA75E24794F70A" modified="2011-01-11" version="1">MDNMQKIFKSLPKEFPKLSKYGECSKTMLTDKFCTGNYKLDKDVSEQYTPVDAYSTAYNRYSFTLNWKKSGNKKCTNQCRQIFDEGFTTSTSCTYDSHTMAHNGTLSLDCGTASFEIFNPDTASKGPSCKHTATEIPYNVFSGSDGIIYKEFCRKWNPKSGLRMVVDSEGTSKIPNPQLDKRTPPATQNKWLNCNFDLRFQPETGAQAGAQCKVTCEDAFAAFPASKCGQNGGQGNSMARSGDNSVRRRPANIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWN6</accession>
    <name>E3QWN6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribosome biogenesis regulatory protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_10418</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in ribosomal large subunit assembly.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the RRS1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697390">
        <property type="protein sequence ID" value="EFQ35274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099294.1">
        <property type="nucleotide sequence ID" value="XM_008101103.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWN6"/>
    <dbReference type="STRING" id="645133.E3QWN6"/>
    <dbReference type="GeneID" id="24415783"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10418"/>
    <dbReference type="eggNOG" id="KOG1765">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065163_2_0_1"/>
    <dbReference type="OrthoDB" id="28455at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007023">
        <property type="entry name" value="Ribosom_reg"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04939">
        <property type="entry name" value="RRS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="147"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="85"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="170"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ35274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="193" mass="22212" checksum="64F22D71F645605C" modified="2011-01-11" version="1">MALPISRPKLPVAVNKPTPYTFDLGLLMANDPNPVELDKSAIEESLAATARDGAQALINQLLTTCPLQSTTEGVLLSLPPPSTELPREKPVPKPKEPTKWERFAAKRGIKPKTREQRRNLVYDEDTKEWRAKWGYKGMNKKGEDDWLVEVDPKEEMNRKEGTTVQGDKRRERKERIKRNERKMRKNQREAGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWU7</accession>
    <name>E3QWU7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribosomal protein L32</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_10479</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697391">
        <property type="protein sequence ID" value="EFQ35335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099355.1">
        <property type="nucleotide sequence ID" value="XM_008101164.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWU7"/>
    <dbReference type="STRING" id="645133.E3QWU7"/>
    <dbReference type="GeneID" id="24415844"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10479"/>
    <dbReference type="eggNOG" id="ENOG502T5GS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_585273_0_0_1"/>
    <dbReference type="OrthoDB" id="62952at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056632">
        <property type="entry name" value="DUF7730"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF1">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24864">
        <property type="entry name" value="DUF7730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="DUF7730" evidence="2">
        <location>
            <begin position="19"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="357"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ35335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="476" mass="54661" checksum="2FB6273ABF970705" modified="2011-01-11" version="1">MTNLTLTIPLPAHQHPASSKCLLGLPLELRNHIYHHTLVAPPKHSRTHDDDCHFRYNHNATSIEPAACVVLDVAVDPVPLQYTYRHDRLSQCRCAKRATLNFLLACRQVHREAAPVFWSANTFVFDHSDDFTICVGARLRPAFCPLLRHVYVASADCEENPLWTTRNLFSGAIISTSDKIPRWLQFWGVLNQCRGLRTLAVQPEVVQRHSADLAALSRRLPALERLELTWMGKYTDDEAPHVPSGRSLRACGPVQREMVFVRAARSVDLGAADFGGVAWCKELYRDFTTNFCVHLDTIVRNRFLGCGADGPDRYRIELHTGRVEAGLNDARRTWNVKLPTGKTARLDFLAVPQSRETRMRLKRQRRAQDAARRASGKPTVAEERVQREIQARRAENKSREAEEEARERELVLAERRRREEEREANERREREDRRAELQRAVEAAREERRVERKRVVRRGVEEEVGELALRGGSFLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>E3QX83</accession>
    <name>E3QX83_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10615</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697393">
        <property type="protein sequence ID" value="EFQ35471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099491.1">
        <property type="nucleotide sequence ID" value="XM_008101300.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QX83"/>
    <dbReference type="GeneID" id="24415980"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10615"/>
    <dbReference type="HOGENOM" id="CLU_2904070_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="62" mass="7010" checksum="C386CE5A0061D72B" modified="2011-01-11" version="1">MCECNDWQTQPELYDWPSLSWTMSRSRQSTSGASGGMPSDLVVQPPPGSNSEKEENEKKKLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXH1</accession>
    <name>E3QXH1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Increased loss of mitochondrial DNA protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10703</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697395">
        <property type="protein sequence ID" value="EFQ35559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099579.1">
        <property type="nucleotide sequence ID" value="XM_008101388.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXH1"/>
    <dbReference type="GeneID" id="24416068"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10703"/>
    <dbReference type="eggNOG" id="ENOG502RZTE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_113779_0_0_1"/>
    <dbReference type="OrthoDB" id="5299849at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018815">
        <property type="entry name" value="Incr_loss_mito_DNA_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28029">
        <property type="entry name" value="PROTEIN ILM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28029:SF1">
        <property type="entry name" value="PROTEIN ILM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10311">
        <property type="entry name" value="Ilm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="190" mass="21651" checksum="1136B91E429FEB15" modified="2011-01-11" version="1">MAIISARTIVTSLSLFHITLAYFFITNPATIADQGLVYILGESMGMPYARSFENKSPALAFLAAVLGMLGVSDLVTLSMPEEVWLIYHWGTQAPFRLFLSMIFVIYTFLFGPSSPLYGGSTRDGNRLAHPLAQANNPRYTPSTWGGDALKNRVFLTFAFLEMLCWFWAWMTLREEQEQFQKKQRKRRDSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXW4</accession>
    <name>E3QXW4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histone transcription regulator 3 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_10857</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Has a role in a nucleosome assembly pathway that is required for the integrity of heterochromatin and proper chromosome segregation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the HIR3 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697398">
        <property type="protein sequence ID" value="EFQ35702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099722.1">
        <property type="nucleotide sequence ID" value="XM_008101531.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QXW4"/>
    <dbReference type="GeneID" id="24416222"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10857"/>
    <dbReference type="eggNOG" id="ENOG502QQX4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001419_0_0_1"/>
    <dbReference type="OrthoDB" id="77564at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000417">
        <property type="term" value="C:HIR complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033053">
        <property type="entry name" value="Hir3/CABIN1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15502">
        <property type="entry name" value="CALCINEURIN-BINDING PROTEIN CABIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15502:SF7">
        <property type="entry name" value="CALCINEURIN-BINDING PROTEIN CABIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="319"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="781"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1690"/>
            <end position="1741"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1753"/>
            <end position="2010"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="330"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="340"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1766"/>
            <end position="1775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1798"/>
            <end position="1816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1836"/>
            <end position="1851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1879"/>
            <end position="2010"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ35702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="2010" mass="226435" checksum="5B7B9DDFC6BCE161" modified="2011-01-11" version="1">MPAFQAINVETEENIDDEIDTTRELHVDEALKRFQNALKLHAQGPRFFDEAADAYDDLFKSEIFKYPEAVTEYERAERQPEHLITDPALASDLDLQVAEVDTVGSSLPQAFFLAHKNRGQFLLDRTRHAARSAGGDAPAYFEKDEALHNMYNALTDFNAALDRDPSDAELWRRTARVAASLKSTRINRYCLEAAIELDDDPTVLEVEPPSLAEGFAGQQLKEQLQVLADEIALSHPIMGPWVKRDMPDFIKRHIDPIPFLPDPTKELGSARTTVEEVGATRLTVTCPTASWADLGMALVQFILEKGQISQAIVIELPETDDDEDVVMESQPEQDSQPNRSDSKDKDEAVTKEDKPEDTEKAESSKSMSKEAPKPPENTRKSRSSSQPTRKRSQSAAGIPEGQEEESLVEKRSKRIRRRETAAAEEVVDPSAVLASQLAPCQAADQNLFQATKNMLENIGVTDQATLDRISQVLDSLASEERAASIKNQATVDLRNAIVSFNEENAKILLNKQAQASLSLSSFLEHAKGGSQKTLVIPPFKETQGIAAFVKRVNSSWMTAQEVAYEWLKTICPSYLETKWSDVMKTAVVQVISRFDQDILLSINYDLDRARHSADAEKEFGFIKSVVEMLFEIHLDVYERITNPNSVVDYSIRVEAKGRLGRWLDLASALLREATPEGNEKLTGRFLWAAIFSTTLTENASREYILQCWTSLRDFLSESHFDQLYLPNNPVIPEVSEAAADREISKLTTMDFFLGLFQDNVSDPVAVIDNLEPVLNPGSVYVPVPSDETAKDEEGSSSGRSKTKKVPIKECASQSLQDLWRFLLGTSTELRLFLWTRLSDAYASIKYSTKQFSCHLKAIEMLTADLESDGYLKNAPETRPPLLLKMLKSLDELLITALSLALNDSSAFDIVDDDHLKSTSTALIKLSCMLHASAMHDDEIRIGMTRAPPSSPSFQPFLNKLREIQVRVWCLQYTVIKVGVNQNRALFPNPEMELADFLSAIHQVVGLRKCCKASNKIFLKMMRVELLKFKEVENWEDYLGQVLYDLHGLKLGVGAGEVQDHGCPPEKLEKRNAMQLVDKITVLARRMPRKDLLKSDLKTTIEHMQGAIGQTKSTPQMIHNLRNFTEYLKRPIHPLRLYQALTGGVQLDVVAVNTPESALAKHGWFFLLGMIALTRFKQVDLSKRQTPGATDDLRLAATFLRLQLQFTPDKWDAWFRLAECFDYELDEAVLWSADKMNKERGELLKFQRNSIHCYTLALSNSWEVDIDDEDEDPLYELYHNFAMRLYASSREPLAMEPFQHADLERFFIEPTGAGTFQKVLHDQMQDYKVWKYAAGLFKRAMRRKPQDWRNTYMLTKCLWKMYQKPIDELSQKDRETRPSVGYLVSALEHAVEVVSAVPKSRHSDPILEPHYKIVSIIYKLVVRGDLKPQEGADILSRQPFGMELGDDITLDDNEDWEEYVIRNLHHLRDKDKSNWQHRIIMRHARLLFDEDGESPELVQAKAAFNVLRESMFTKTMVMNVWKCDAERPGRHHVYTSQYIRFMVKILVVMNDRVNLEMVLRRLRKKGADFYHFSELWQMCSMAYLRLLRQGFQVPPTLDDPFKSTSLEELEIMADRITEWAGGPLTDIPAFNCLKETIELKKLNGGLMKAGAIDDLINDCYALIYQEIGPTLPGPEPHEVLEARARARAREEANGGLELKPSSSLGNLLNPIAAQDSGANGEGDKTAAPEAAPRRRTGVRRPDIIRKAEQAFARFSEAPKSSVAPSKSRVGSVSSGRNGTHTPAGDVGEGSDADDRPGEDGEDTEMKDDTMMEGDQGEEAPAQATAGSSPRGSIHDSADDESELSDVPDDWDEQPPPSLMFPNLRKSVDSAREGGGNESSDGGDEEEDEGGEEEGEEEGEEEEEEEEGGEVEVEEGEEDEGVEEEEAEAEEGEGDEEEEGDGEEEDEDEEEGEDEEVEEVEEDEEDQEGEEDEEEQEDDEEQEGGEEQQDDEEQEGEEEQEEGDVADEDEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QY99</accession>
    <name>E3QY99_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_10946</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697401">
        <property type="protein sequence ID" value="EFQ35837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099857.1">
        <property type="nucleotide sequence ID" value="XM_008101666.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QY99"/>
    <dbReference type="STRING" id="645133.E3QY99"/>
    <dbReference type="GeneID" id="24416311"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10946"/>
    <dbReference type="eggNOG" id="ENOG502R8I5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018354_4_2_1"/>
    <dbReference type="OrthoDB" id="9983560at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050432">
        <property type="entry name" value="FAD-linked_Oxidoreductases_BP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878:SF91">
        <property type="entry name" value="FAD BINDING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G12070)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878">
        <property type="entry name" value="GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003181071" evidence="3">
        <location>
            <begin position="18"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="4">
        <location>
            <begin position="125"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ35837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="575" mass="60879" checksum="A2C67164FE6DF963" modified="2011-01-11" version="1">MVSFLNLLALAPAAVSAASIGGPLAHLARQSDADCRCYPGDACWPTAADWDAFNQTVGGRLIATVPIGAPCHDSSFGSYNEAECTALQNAWGSPETHIKTSSSVMAAFFANQSCDPFLDRSDRCIIGTYVQYAVNATGADDYVNTIKFAQDNNIRFVIRNTGHDYLGKSTGAGALALWTHHIKDIEVLDYKSASYTGKALKVGAGVQVGEAQSVAHANGLVVVGGNSPTVGIAGGYTQGGGHGPLVSKYGLSADQVLEWEVITTAGQRIVATPTNNTDLYWAMSGGGGGVYAAALSVTLKVYPDTITSSANLTFTNSGISDDVFYGAIKSYLKVLPDIVDAGAVSIWLLGGGAFLMQPTTLPNKTKDELQTLLQPFLNALDEACIEYNYNIEQYDTFLDSYNAMNPEPAVTEYNIGGRLMPRTLVADDASLANLTDALSSIADNGGLISGLTINVSRPDDAVPNAVTPAWRSALFSAVVGTSYSREKFSTLVIGQNEVTDVLLPKLKALTPGGGAYLNEADRNEADYEDVFYGGNYAKLKSIKQKYDPTSTLYALTGVGSDDWEVRSDGRLCKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZK3</accession>
    <name>E3QZK3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FAD binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11436</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697417">
        <property type="protein sequence ID" value="EFQ36291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100311.1">
        <property type="nucleotide sequence ID" value="XM_008102120.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZK3"/>
    <dbReference type="STRING" id="645133.E3QZK3"/>
    <dbReference type="GeneID" id="24416800"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11436"/>
    <dbReference type="eggNOG" id="ENOG502S0G3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023303_1_0_1"/>
    <dbReference type="OrthoDB" id="3433125at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053221">
        <property type="entry name" value="Burnettramic_acid_biosynth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38887">
        <property type="entry name" value="CHROMOSOME 21, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38887:SF1">
        <property type="entry name" value="RAS MODIFICATION PROTEIN ERF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="441"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="453"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="504" mass="55651" checksum="BE486BC2AC888EB5" modified="2011-01-11" version="1">MTSTLLKQGKKLATKAAQEALKEARGERDKSRKNQKTNLIKKNDPVDALIRVAASAVGLVSEIAQYRQEKKGSGDIEVAEDTYSPNQTITSAQLNEDIWRQDEAGRDTEVRETETKSPKEPSDLAKAFLQRHPHHSNVMENVIIQLPVLIPQRRPKKRARGFVRAYSPVLADAGIDRNTFLDFIDTFNQALEPNPYLYAINLAGLAGMATPEPFVLLVGIAVAFATDAVMETHSRSKSAKFLDRINAEFFVPRGLVCLVATWKPDAGEDEQLLTAVDFDGRAVEKPPKMGLAQQMRDVVTQKVSSEEIMKGFQKGICGRMKASSGAFQWPNPAPLIFPSPEETSEAMITKRDGTKKNKIDRGEIWLDDFMDKRAQAKWIHGNPDSTMTVSLPRPQFRSRYADPSHAAASGDIVAFFTGGRWSTKGKVTSEVHSGMPDFQAQGEMRVPAPTGNESKDKPIQKKDKSGKSCSSGFMRVLQKDVLYLIIVNIPSSTDNNMVSGISTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZL0</accession>
    <name>E3QZL0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_11443</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697417">
        <property type="protein sequence ID" value="EFQ36298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100318.1">
        <property type="nucleotide sequence ID" value="XM_008102127.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZL0"/>
    <dbReference type="GeneID" id="24416807"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11443"/>
    <dbReference type="eggNOG" id="ENOG502TDD9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1906593_0_0_1"/>
    <dbReference type="OrthoDB" id="10415871at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179014" evidence="2">
        <location>
            <begin position="23"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ36298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="133" mass="14602" checksum="7589D86DC3A0B454" modified="2011-01-11" version="1">MLARGLCAGVLALASLIQAAPATGVADAELESRYIYTQREASGEKGNAELESRYIYTQREASGEKGNAELESRYIYTQREASGEKGNAELESRYIYTQREASGEKGNAELESRYIYTQREASGDKGDAELDSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZY2</accession>
    <name>E3QZY2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Microbial-type PARG catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_11548</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697423">
        <property type="protein sequence ID" value="EFQ36420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100440.1">
        <property type="nucleotide sequence ID" value="XM_008102249.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZY2"/>
    <dbReference type="STRING" id="645133.E3QZY2"/>
    <dbReference type="GeneID" id="24416912"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11548"/>
    <dbReference type="eggNOG" id="ENOG502RY8X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024412_0_0_1"/>
    <dbReference type="OrthoDB" id="9985428at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="entry name" value="Leucine Aminopeptidase, subunit E, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012664">
        <property type="entry name" value="CHP02452"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019261">
        <property type="entry name" value="PARG_cat_microbial"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02452">
        <property type="entry name" value="TIGR02452 family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35596">
        <property type="entry name" value="DUF2263 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35596:SF1">
        <property type="entry name" value="MICROBIAL-TYPE PARG CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10021">
        <property type="entry name" value="PARG_cat_microb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="Macro domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Microbial-type PARG catalytic" evidence="2">
        <location>
            <begin position="119"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ36420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="360" mass="39090" checksum="CAFE79D1A20DB3EB" modified="2011-01-11" version="1">MSDKSRQTSLFEFAFCRRGGDQTPKSQDTTQRLSQDTSQPSSSSSPAPSSSSSATTPQHSQSRSQSQSQSRHTGGGDRSNPSLASVSAETRAVLPQVLPHLPHLDATKSESLHMDYLPPLKSSACPAHRPRARIRIVNADSLNAAIDLAALRPDGGRVAVLNMASDIHPGGGWLKGAVAQEEAMCYRSSLYLSLHARYYPLKRRGGVYTPDVVVVRGDMAGGHRLLVPGVAYADLPVVSVLSVAAIRRPEVRRRQVVTAAGTREDVYVFARAADRALTMEKMRLCLRMAASRGHSLLVLGALGCGAFRNPPEEVAACWLEVLDEAEFGGGWWREVWFAVYDRKNEGNFEVFDHVLGGVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>E3R059</accession>
    <name>E3R059_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Prostacyclin synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_11642</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697428">
        <property type="protein sequence ID" value="EFQ36497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100517.1">
        <property type="nucleotide sequence ID" value="XM_008102326.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R059"/>
    <dbReference type="STRING" id="645133.E3R059"/>
    <dbReference type="GeneID" id="24417006"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11642"/>
    <dbReference type="eggNOG" id="KOG0684">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018012_4_2_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11040">
        <property type="entry name" value="CYP7_CYP8-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053007">
        <property type="entry name" value="CYP450_monoxygenase_sec-met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47582">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47582:SF1">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0349">Heme</keyword>
    <keyword evidence="4 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="288"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="450"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ36497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="528" mass="58076" checksum="08A2F39D8A97094A" modified="2011-01-11" version="1">MLSYPGWWTYLLPGWFSFIALLVVIVSDLLRRHLNDPRQSQVREPPSLPHRVPFIGHVIGILTKQVGHFQDVGIKTAVSAVSLPVLSGKMYVIFEPSLMQHALRSPSLSFEPLMIQHAQGLLGVNAKTMSAVHSGLLGDLLRATKPAFAGEQLEIHNLTALNYYASVINNIRPGKTLQLVNLYSWLQRIVTVASAEALYGTRNPITAGSTLVDDVWTLEGGVQKLTFSVLPSITSSGPYNARERLVEALAPLFDLATIDSLPFVSRCRAGVIRAHGITSPEDIARCELAMLHVATVNTVPILFWLVVNIFSQPNLLKALRLECSLLMKRESTSCQGEAGVSEINISISSLQDSCPLLKACFQECLRIYGQALHSRRVHSDTVFTDTQGQEYLFKKGVDVMMPSGVSHTTPRAWGPNAEEFHAARFMNWPQNASREQRAAYMPFGGGKHLCPGRNFATAEILGFMAALCLGTDVQGPDRSETTLMVPGSSPAVLGQAISKPIDFAKGEGLGVKIRKREEFEYVKWRFQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3R109</accession>
    <name>E3R109_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_11946</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697544">
        <property type="protein sequence ID" value="EFQ36797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100817.1">
        <property type="nucleotide sequence ID" value="XM_008102626.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R109"/>
    <dbReference type="GeneID" id="24417309"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11946"/>
    <dbReference type="eggNOG" id="ENOG502RN66">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_3_5_1"/>
    <dbReference type="OrthoDB" id="3897607at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF96">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="247"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="27"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ36797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="307" mass="33551" checksum="5ADA09EF53A73098" modified="2011-01-11" version="1">MAMTSAGMEMLAVGAILLVLNTISVGARIYTRTFVTKAFQLNDALLLVALGAYGALYALLVIGVQGGIGGHVLQATIPGLAISLKVIFFLEIIYVVLTSAMKGSIALTFIHLSRSRVLTLIFWVSIAMDVLISAAFIIYLLVQCKPIDYAWRMLDPAAKGECLPLQGQLYMGYALCIVTAMLDAMLLISPWIMMRGRGLNMRLKLYIYGIFGLGILATIANIIRLVALVKLTSSNDQLYDAAPVFTWSAIEVSIGIIIAGLIELGPLAAKYRLKGFESYVYIDETFSRKKRNDESGIEGYEMRPGKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q272</accession>
    <name>E3Q272_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">CrcB-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_00317</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Fluoride channel required for the rapid expulsion of cytoplasmic fluoride.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>fluoride(in) = fluoride(out)</text>
            <dbReference type="Rhea" id="RHEA:76159"/>
            <dbReference type="ChEBI" id="CHEBI:17051"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:76160"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="taxonomic scope" value="Eukaryota"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903425">
        <property type="term" value="F:fluoride transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003691">
        <property type="entry name" value="FluC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28259">
        <property type="entry name" value="FLUORIDE EXPORT PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28259:SF1">
        <property type="entry name" value="FLUORIDE EXPORT PROTEIN 1-RELATED"/>
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    <dbReference type="Pfam" id="PF02537">
        <property type="entry name" value="CRCB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="232"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="278"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="325"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="349"/>
            <end position="369"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="381"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="445"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="86"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="86"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="99"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002598"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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            <dbReference type="ARBA" id="ARBA00022989"/>
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            <dbReference type="ARBA" id="ARBA00023136"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00035120"/>
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    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00035585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ25173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="480" mass="50762" checksum="6D35C82B8D1955E5" modified="2011-01-11" version="1">MHNGDLRGHDFFAYTGEGDDRSNDDAPPVVDFRRRGTFDMPTALKPRDMSIDSQHAGPIAHDVPEGQETVVKKTVADPVSHIYSSGISPSNSLTATAHSPEETTRIGEGRDRGPLDDVELQDARHDKPDGTAVAPSRRASLLSALEIELYTVSYLIFFAVLGTLARLGLQALTAYPGAPVSFGVLWANVGGSLVMGFLAEDHLLFRPQWAPDAVFIDPSAAARAHLAAKKTIPLYIGLATGFCGSFTSFSSFVRDVFLALTNDLPGAVTAPRDGGYSFMAALAVVLTTVSLSLSALVVGGHLAAALEPDGSSAAYPPGRKILDRGAVLLGWGAWAGAVVLAVLPPRDAWRGQAVFSLAFAPVGCLARFYVSRWLNPRAPTFPLGTFAVNIAGVAVLGICWDLAHAGVGGVLGCQLLQGVEDGFCGCLTTVSTWVTELTALRRRHAYVYGVSSVMVGFAVLVVVMGSLRWSEGFGPLKCTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2S9</accession>
    <name>E3Q2S9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Urea carboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_00052</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <cofactor evidence="1">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_008090737.1"/>
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    <dbReference type="eggNOG" id="KOG0238">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="CDD" id="cd06850">
        <property type="entry name" value="biotinyl_domain"/>
        <property type="match status" value="1"/>
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    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
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    </dbReference>
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        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="ATP-grasp"/>
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    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050856">
        <property type="entry name" value="Biotin_carboxylase_complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
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    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
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        <property type="entry name" value="CPAse_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003778">
        <property type="entry name" value="CT_A_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003833">
        <property type="entry name" value="CT_C_D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18866">
        <property type="entry name" value="CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18866:SF128">
        <property type="entry name" value="UREA AMIDOLYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02626">
        <property type="entry name" value="CT_A_B"/>
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    <dbReference type="Pfam" id="PF02682">
        <property type="entry name" value="CT_C_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00796">
        <property type="entry name" value="AHS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00797">
        <property type="entry name" value="AHS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
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    </dbReference>
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        <property type="entry name" value="Cyclophilin-like"/>
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    </dbReference>
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        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
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    <dbReference type="SUPFAM" id="SSF160467">
        <property type="entry name" value="PH0987 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="Rudiment single hybrid motif"/>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0092">Biotin</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="10">
        <location>
            <begin position="15"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="9">
        <location>
            <begin position="132"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="8">
        <location>
            <begin position="1160"/>
            <end position="1238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ24908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1241" mass="135187" checksum="EC41700DBE7DABEB" modified="2011-01-11" version="1">MSNSRGAVEPKPLRNINKVLVANRGEIAVRCVKACRELGVLSVTVYTAADATSLHVLQADEAIALRGNKTYTDISDAILDVCRSTGADAVFPGYGFLSENVAFAEAVATAGLTFIGPSSASIRAMGLKHEARSIAQAVNVPVVPGTSLLSSAHEAIEGAKRLGFPVILKPTGGGGGMGLQICHDEQDVPKAFATVESRAGALLNNTGVFLEKYYPRFRHIEVQVFGNGTQVVAFGERECSLQRRHQKIIEECPSPFVERTPGLREKMLQAAVSYASHLKYKSAGTVEFLVDDETADFFFLEMNTRLQVEHGITEMCYRIDLVHLMLYQADYERGGQLGIPSDELRGFQQALPRGSAIEARIYAEIPLLDFTPSPGLIQNVSWPQGDGVRVDTWVENGQHITPFYDPLIAKIMVHSPGGRADAQRKMVAALAKTTLQGTQTNLQYLSQVLQSDNFSKGNSLTNFLTAFQVEVCAMQVLSPGVLTTVQDYPGRTTVGHGVPPSGPMDDLSSRIANILVGNDPSVEFLEITMTGPELKFHESAIVAVCGAQVSVTIDDEEQPMWSRIVVKQGQTLKIGSVFGDGLRAYLAVKGGFPEIPLFFGSKSTAPELGLGGLQGRKLQANDIIALSPESGAWAAAATPFSLPPGAMPDYSVSEIYCLNGPFGSEDILTPEGMEMITSSQWTVTHNSSRSGVRLEGPRLKWARTTGGGGGSHPSNVFDYGYPNGGVNWTGEYPVIFSRDRPDLGGFACPVTICSAEMWKVGQLKAGHGFRFQIVTFEDAVEITRRNEGYLKSLAALVDGEETEVTPPVRTFGPQKTTSILHMTQSLGDHPRVTYRQGGDAAIVVEYGEQVADLRNTVCVKMLKEKIAARDIVSIRCEPNLSTLTVHFDPLQIHQSGVLQNLIELDGSIEEVVGVKLAVRELRLPLCVDHPTVKEATERYMESIRPTAAYLPDNVEYLRRNNALESRRDVLDSLVRTPWLVVGVGFFVGTPVMFPLDPKYVFTGQKYNPNRTYTPSGAVGLGGSLLAIYPVASPGGYQLMGRALGTWDMMGTRPGFSPSRPWLFEHFDMVRFREVSREEFDQAERDFEVGRYMFDISDGVLSMDEHIAKFDAAARDPAHQEWRKRQAAAAKEMGQLEQRLFGEWMEAKAADASSQSEEDGDAALDDTLTVESPMSANVWKVLVEIGDVLEKKQTVAILETMKMEIKVLTSDAQAGAVVTKIARTPGSVVSPGTPIVVCQKVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2V1</accession>
    <name>E3Q2V1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Chromatin associated protein KTI12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_00074</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the KTI12 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ24930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008088950.1">
        <property type="nucleotide sequence ID" value="XM_008090759.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2V1"/>
    <dbReference type="STRING" id="645133.E3Q2V1"/>
    <dbReference type="GeneID" id="24405439"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00074"/>
    <dbReference type="eggNOG" id="KOG3062">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027147_2_0_1"/>
    <dbReference type="OrthoDB" id="9972657at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013641">
        <property type="entry name" value="KTI12/PSTK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12435">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08433">
        <property type="entry name" value="KTI12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="148"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="306"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="162"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="207"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ24930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="396" mass="42714" checksum="53B0466CCC6F3C5B" modified="2011-01-11" version="1">MPLIVVSGLPTSGKTHRAKQLQAHLASRIAAAAASSSTPAEGGKQPPYRLHYISDSTLSIPRDVYDLDPQKVRAHTRSANASEKDARAAVYGAVKRVLSDRDIVILDGLNYIKGWRYQLHCEAKAVKTPSVVLQIGCGVDRARGINEERLRKRRRRRRSEGEGAPTATAAATAMTTTTAPAITTTTTTTGTAEDPATNDRTTTDAGGGEEEEEPYEPDNWENLVLRYEEPNPMTRWDSPLFTLIWDDDAAQAARVFNDVWDAIAGTGRKAVKPNQATVQRSRDAGGDYLYVLDRETQDVVRRVLEAQGEGGEDGGEVTVPRGAAGAGAGAGAGTDEGLVVRLPGRKVGLPQLQRLRRAFVGLNRGGIGLEGVGSFSVERMRESFVGYLNDSFDQEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3E1</accession>
    <name>E3Q3E1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Clr5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_00687</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089563.1">
        <property type="nucleotide sequence ID" value="XM_008091372.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3E1"/>
    <dbReference type="STRING" id="645133.E3Q3E1"/>
    <dbReference type="GeneID" id="24406052"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00687"/>
    <dbReference type="eggNOG" id="ENOG502RS6D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2961413_0_0_1"/>
    <dbReference type="OrthoDB" id="4736382at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ25543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="59" mass="6930" checksum="6459A4793188A177" modified="2011-01-11" version="1">MVGQISYTEDQIIFVLEQVLADKKRDIVLYEYQKKFGKSLSASQLRYIKNKYGHDPEFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3J9</accession>
    <name>E3Q3J9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00745</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089621.1">
        <property type="nucleotide sequence ID" value="XM_008091430.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3J9"/>
    <dbReference type="GeneID" id="24406110"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00745"/>
    <dbReference type="eggNOG" id="ENOG502RJJE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_687207_0_0_1"/>
    <dbReference type="OrthoDB" id="3492129at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="315"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="419" mass="45657" checksum="457CF906E7ED435B" modified="2011-01-11" version="1">MTTPVDNHPRPSLHPLWSSQYNFGGFPRSDGIAPRSDGIAPAPSSYYSPSDRSPKSLPMPVFPSDDGSMRQHERAMVDRLGHRIRQAQRVDLSPPKSANRPRPLSPLAEHSASHARRYSAAAPISPRRPGPPPSATPVSPPATSNRRQTLASETRSMLLAGLGEEVQRRQSEAGTGYFARSKDAEKRLHLEQLRAWGHVYLGDAKTSDVFVQAVALRRQSDASTNSDLSTGDSSPSHMPPTPTTPPHQTSIRARVRPRALERKPFLIQRTFDIEQLRSTVPDPLPSSASVDHRRRPSLQSLKTAPLPIVSPTRPSAARRMSSSAALNPPPYSRGLKSGDARITPSRGVTTMPIHLQYARTSLPVLAALIVSGHITTGDVIDLPLPHPEAWPSTVAYVYTGQGDVTDAVRENILYLAGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3R5</accession>
    <name>E3Q3R5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_00811</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089687.1">
        <property type="nucleotide sequence ID" value="XM_008091496.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3R5"/>
    <dbReference type="STRING" id="645133.E3Q3R5"/>
    <dbReference type="GeneID" id="24406176"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00811"/>
    <dbReference type="eggNOG" id="ENOG502S5BG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010915_0_0_1"/>
    <dbReference type="OrthoDB" id="3200163at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24173">
        <property type="entry name" value="ANKYRIN REPEAT CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24173:SF74">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="505"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="651"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ25667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="888" mass="100336" checksum="6621E8BADF698810" modified="2011-01-11" version="1">MDFGVASGVAGFVSLLIQIASGINKLRDILKNAEQAPAELEQLLSDLVFLQHLMEGAKGLSRDPALEHCEATCSLLVQGLERLYQKLLMDCEKVKGPKMMKTLLAFRHWKKDVEDLLRNIQAAKINLILLTSHRTSQCLSEMMLVNQLHITSAQVSIPATRTDSAVSPTPLDASSRQSPGSFAPAISSRDIVALRPKARGNCLSRSCSCSCHRTQKTSRRFWALEYTHPTVFRRTCDSPSCNTSKYGGTFRIALSQLGVRWAAAIQFYILAESGKFSMRPCFEMERIVPYTSPGFELLWKCAQDLIGVEEAKRGLIELERTDPSFHTHVNPDGKSYIEELLRYTWWGFEKQFQLLELFMQEFKMSKGTERPGFLSLCAKWIGEGPHIDLLETLFTLGFDATVADTQNWPEVSSPNWRSEGMTPDPFFLEYISMLCKDNQGFAGLTPLHEAIVSGSPDSIRKLAPRFDINGRNFLGQTPLHFAVVNHLHLEVFLEFNPDLDAPDNYGNTPLMYAAAENQEESAMMLLDAGADVYAEESRYNRTFIEYGALRDHWKLVLNCLSRIESLMGKKVAENWAEHATLLFHVQYPNTLNNRNVTFRQFLVKCPDVNFFYDNLRTKSQENTLLHSASSRSDLDALLDNGFKLISHRNSTGRHPLIEAADRAVPRLVEGLLDNGADIALKDHWHRTALHHALARLEKVSYEAIYEAIDTILILVTHGADLLSRDNCRCPCSPEGCLLGVELMHTVHQIRGHVHFPAWALEWVCLVYESRGTDGAKTAIASLLRRTKHKEMGMTHICCRRHPPFPWGPSFVSGGPSCIPDDDIDDILDEESEFIEILEKEMTQTTVQKYELLFDEWVRHIKSSLAVLCKEAVKYDKKVENDENGKKAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3Y7</accession>
    <name>E3Q3Y7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00883</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089759.1">
        <property type="nucleotide sequence ID" value="XM_008091568.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3Y7"/>
    <dbReference type="STRING" id="645133.E3Q3Y7"/>
    <dbReference type="GeneID" id="24406248"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00883"/>
    <dbReference type="eggNOG" id="ENOG502QS8D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012617_2_0_1"/>
    <dbReference type="OrthoDB" id="5232429at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056362">
        <property type="entry name" value="AtuA-like_ferredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010839">
        <property type="entry name" value="AtuA_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47585">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47585:SF2">
        <property type="entry name" value="DUF1446 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G11420)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07287">
        <property type="entry name" value="AtuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23544">
        <property type="entry name" value="AtuA_ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyclic terpene utilisation N-terminal" evidence="1">
        <location>
            <begin position="3"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="AtuA-like ferredoxin-fold" evidence="2">
        <location>
            <begin position="162"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ25739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="232" mass="25783" checksum="C73618753B3F6D7E" modified="2011-01-11" version="1">MFAAEGGYQAEATFYINGLDVDEKVAMMKNQLAHLFKDANFSRLSIEQYGTQVRNPSSQQAGTVQLRVFAQARKKEDIAGRQFQGSDIRRADAKLARLPHVAGFPNDGPKESTIDHRVLLGTGDSIAVPRPENIATYKVLRPSADTADPIDLFSLGPTEFAPLGSIVHARSGDKADNSNVGFFVRNEDEYPWLRTLLTVSRLKQLLGDDWFNNNPDQRLERVEFPGINAVHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q463</accession>
    <name>E3Q463_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">IQ calmodulin-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_00519</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089395.1">
        <property type="nucleotide sequence ID" value="XM_008091204.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q463"/>
    <dbReference type="STRING" id="645133.E3Q463"/>
    <dbReference type="GeneID" id="24405884"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00519"/>
    <dbReference type="eggNOG" id="ENOG502QRIN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020021_0_0_1"/>
    <dbReference type="OrthoDB" id="7344096at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd23767">
        <property type="entry name" value="IQCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044159">
        <property type="entry name" value="IQM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31250">
        <property type="entry name" value="IQ DOMAIN-CONTAINING PROTEIN IQM3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31250:SF27">
        <property type="entry name" value="IQ DOMAIN-CONTAINING PROTEIN IQM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="141"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="257"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="457"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="651"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="24"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="82"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="157"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="176"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="262"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="330"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="652"/>
            <end position="710"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ25375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="710" mass="78609" checksum="64A1E6D8BDA5191F" modified="2011-01-11" version="1">MTKPNRHELDNLPVPAEQPYTGGAAVSSATATAAAAHAPGPQKSPLLHYHVPCAANVITPPASPPVPPSSLQEDDSHSNFSATAVTGTAAATRPSSDDTCSLAQSQTSTAYSSRREYMDSLVPPSHDEFEKIAEVQRAREEEFKKNKSKLRSMQTQHLHDHFHTPRHSQDGHKDAAAAAAAAAAAVGDEAQSQPQSQSQPGAGGRERSDSDAISRAAALIQRNYRGYRVRREMQGLSLDPSTRWVSAIDELQFRELNRPRAKSSASAAGLAAGNSDQHSVLSRDSEGGMSRPATARENWKKAATIARRAGHDDLESDSDSSASSSDPEETPEHRDEKRRRRDEAVARRKKDSKMMGLQYFLEMVDLKHRYGSNLRVYHEEWKKTDTNENFFYWLDHGGGRNVEMEACPRDRLEREQVRYLSREERQYYLVQVDDEGRLCWAKNGARIDTTEAYKDSIHGIVPADDPTPAWSQNKLPPPPDSGNHNDDGNDDEDDDSRSESSVESALEADRAAKYATPELDGATGVRKVSHISAATVFNKLLRKSVKKNTWIFVADTSFRLYVGIKSSGAFQHSSFLQGSRISSAGLIKIKDGRLSSLSPLSGHYRPPASNFRAFVRNLKDAGVDTSHVSISKSYAVLVGLEVYVKTRQKGKRTLERATRKKDKIVSPEAARRREEAERDKSESAAREREVLEREAEEREEIERRPGSCGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4A5</accession>
    <name>E3Q4A5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00561</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089437.1">
        <property type="nucleotide sequence ID" value="XM_008091246.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4A5"/>
    <dbReference type="STRING" id="645133.E3Q4A5"/>
    <dbReference type="GeneID" id="24405926"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00561"/>
    <dbReference type="eggNOG" id="ENOG502RSG2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013866_4_2_1"/>
    <dbReference type="OrthoDB" id="4491390at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053175">
        <property type="entry name" value="DHMBA_Reg_Transcription_Factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38791:SF13">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38791">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="2">
        <location>
            <begin position="10"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ25417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="551" mass="62219" checksum="1E114735CDD61995" modified="2011-01-11" version="1">MVNTGKPSGGCKLCRARRIKCDEGKPFCMRCKKSRRQCPGYRDPFEANIRDETKATIKRFKKSRGEEGSDEEGKDITPICNKKCLKTVAGPKYKTYDYSNPVTFPWHNNDNTTDEDEDIPRSIFDSLDEQASCYFLSEFIIVPQTPTARGYYRFLPRFLSGKKVSKCLYQTYKAVSLAALANRRTVNASAALFHAQGHYVRAVRAVNKAIMDPQEVLDDQTLGAVLMLAFYEILTASRGSIAAYTDHMKGAAIIVKLRGQKGLETPEGEELFAITRNQCLSIHCLPNSPEVAEFTWLLHHECRGRMQHAIATMDIQSSQIRQDVDRLLGPGDREPGTIQNVLDVLKRAQALEARFRKLNNDPSPQWKVDTLEWVPEGSDEELDTARAFTGPVYGFFNLPLAVLHVATWCCHLMLTTTILRCMAWLVSPDDYREGEDYEMLKRSAQLRVEDIIAATPFFCKWNGYGVVVAQFPVGKTKIDDPLKGAAGLMIIWPLVTACSSDFATPRQKRFLRGRLKYLSEVAGIKQASVFYNMQDTSSPFREIERDRNQGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q500</accession>
    <name>E3Q500_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Ribosomal protein L11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_01309</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the universal ribosomal protein uL11 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ26165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090185.1">
        <property type="nucleotide sequence ID" value="XM_008091994.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q500"/>
    <dbReference type="STRING" id="645133.E3Q500"/>
    <dbReference type="GeneID" id="24406674"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01309"/>
    <dbReference type="eggNOG" id="KOG0886">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074237_5_0_1"/>
    <dbReference type="OrthoDB" id="1478556at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00349">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.250:FF:000002">
        <property type="entry name" value="60S ribosomal protein L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1550.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.250">
        <property type="entry name" value="Ribosomal protein L11, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1550.10">
        <property type="entry name" value="Ribosomal protein L11/L12, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00736">
        <property type="entry name" value="Ribosomal_uL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000911">
        <property type="entry name" value="Ribosomal_uL11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020783">
        <property type="entry name" value="Ribosomal_uL11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036769">
        <property type="entry name" value="Ribosomal_uL11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020785">
        <property type="entry name" value="Ribosomal_uL11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020784">
        <property type="entry name" value="Ribosomal_uL11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036796">
        <property type="entry name" value="Ribosomal_uL11_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00298">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03946">
        <property type="entry name" value="Ribosomal_L11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00649">
        <property type="entry name" value="RL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54747">
        <property type="entry name" value="Ribosomal L11/L12e N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46906">
        <property type="entry name" value="Ribosomal protein L11, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00359">
        <property type="entry name" value="RIBOSOMAL_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL11 N-terminal" evidence="7">
        <location>
            <begin position="13"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL11 C-terminal" evidence="6">
        <location>
            <begin position="74"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ26165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="165" mass="17708" checksum="726F527EE49C6013" modified="2011-01-11" version="1">MPPKFDPNEVKVIHLLATGGEVGASSALAPKIGPLGLSPKKVGEDIAKATGDWKGLRVTVKLTIQNRQAAVSVVPTASSLIIRALKEPPRDRKKEKNIKHNKSVPLDEIIEIARTMRHKSFSKSLEGTVKEILGTAYSVGCQVDGKTPKAITEAIEAGEIDIPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q526</accession>
    <name>E3Q526_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00937</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089813.1">
        <property type="nucleotide sequence ID" value="XM_008091622.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q526"/>
    <dbReference type="GeneID" id="24406302"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00937"/>
    <dbReference type="eggNOG" id="ENOG502R9XS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_605512_0_0_1"/>
    <dbReference type="OrthoDB" id="4851861at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="342"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="164"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="200"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="452" mass="49740" checksum="8EDA6AA8ED09393A" modified="2011-01-11" version="1">MSLNMAQPTLEHGRQVVLGSRLRPVKIQDAVYSRLIEMAEDDEDCEFARWLLLQVCEIFRDDIDDQKAIVPIGMGERDYTAGWRDALATIRGLSSLCLKGPQEDGDPSRPEPPDVFSARYGDVEQYYQKGLGIRWEEERERLNWGDEVLARCGFTGATAEAFENDQQNSSTNDSQASSSLINTPSNVSISDSVLEALFPPESSAELSSASNGSSPSKRAPSTPDSRQPPNGHNRNLNKSDIIRGLDTTALLAHFERQSRLSERRIVAELGRTSLLRQAIFQDRFFGRVPSFAGAPGGDDLVNDEYDATDITDGINEPFLGEAQQMRAVRQVKTLFRQWRKAAAEDQGEADEGSDGGTRVTGREDGDDDDEGVSSDSASLSHAPEPWLDSHAGAAPPPSPGSESVYSDDTLWPSAASEPCDETSALVAPPTHHYCLPDDQWAMLHRHRRLHQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q549</accession>
    <name>E3Q549_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">NupC family nucleoside transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_00960</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089836.1">
        <property type="nucleotide sequence ID" value="XM_008091645.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q549"/>
    <dbReference type="STRING" id="645133.E3Q549"/>
    <dbReference type="GeneID" id="24406325"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00960"/>
    <dbReference type="eggNOG" id="KOG3747">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016813_1_1_1"/>
    <dbReference type="OrthoDB" id="6075923at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005337">
        <property type="term" value="F:nucleoside transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008276">
        <property type="entry name" value="C_nuclsd_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011657">
        <property type="entry name" value="CNT_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002668">
        <property type="entry name" value="CNT_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011642">
        <property type="entry name" value="Gate_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10590">
        <property type="entry name" value="SODIUM/NUCLEOSIDE COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10590:SF4">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 28 MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07670">
        <property type="entry name" value="Gate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07662">
        <property type="entry name" value="Nucleos_tra2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01773">
        <property type="entry name" value="Nucleos_tra2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="206"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="290"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="322"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="367"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="453"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="489"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="513"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="552"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="588"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="domain" description="Concentrative nucleoside transporter N-terminal" evidence="9">
        <location>
            <begin position="211"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoside transporter/FeoB GTPase Gate" evidence="11">
        <location>
            <begin position="293"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="Concentrative nucleoside transporter C-terminal" evidence="10">
        <location>
            <begin position="396"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ25816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="612" mass="66483" checksum="4E9DD0A4CF00E551" modified="2011-01-11" version="1">MHSAPTASPGGDRSATEVSSEKHGRPENDVGAGEFEVGRAPLPKSVEMEKPSAKDSEAAATAAAAEADTSDVEVGTNQTDSMRDSKGKRAKWLRFYRKFKLPVHMFVWMLFTAWWVVGLVFQRDRLGWLKPFLVYLAITIRIVTLWLPASAVMVPLRFVWMHTVSRVYDLTPEKLHQPLAALLTIGVFLVGSMIPEEVGENTRASRAISLFGLLLMIGLLTLTSRDWRKIPWHTVIGGMLTQFIIAVFVLKTSVGYDIFAFISEMARTLLGFAKDGLEFLTDTQVTTRTWFIISVIPAIIFFISLVQLLYHCGLLQWFIKKFAVFFFWSLRVSGAEAVVATATPFIGQGESAMLIKPYVPYLTLSEIHQVMTCGFATIAGSVLVGYIGLGLDAQVLVSSCVMSIPASIAVSKLRYPETEESLTKGSITVPDDEEKAANAIHAFANGAWFGLKVAGMIVATLLCIISFVALINGILGWFGKFLGIDNPPLTLQLILGYVFYPVAWCLGVPKQDLLVVGELIGIKIITNEFVAFSSLSSNVEPYISMSPRSKLIATYACCGFGNIGSLGTQIGVLSQIAPGRAGDVSRVALSALFAGVLSTLTSASVAGMLYTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q558</accession>
    <name>E3Q558_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00969</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089845.1">
        <property type="nucleotide sequence ID" value="XM_008091654.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q558"/>
    <dbReference type="STRING" id="645133.E3Q558"/>
    <dbReference type="GeneID" id="24406334"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00969"/>
    <dbReference type="eggNOG" id="ENOG502RSGV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1030632_0_0_1"/>
    <dbReference type="OrthoDB" id="4851546at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="218"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ25825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="269" mass="26940" checksum="4DA3351782A81781" modified="2011-01-11" version="1">MNMGEDNAFDGEERHQEERRQMKDAETANAEAVAAGARLAAGSGPNALPLDTNQLLSVLGLLDDQPLGTPVVVAAPAASGTSLNNNANVPTVTSFVTVTLPAQTIMVTLSTTITVTGTPPVPSTIPVPPPPPPPPVTTSSPPPPPPPPPMSTAPPPPPVVLPPPPPPPQSPVTGITTPLMGSGPLTIPPLISATSHTSSISASATSSPKGGAAGTPTAVVLLGVFGGVAGVSLLAMGAFIYGLMRKRKVKGETESGSVESMQIGRPMPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5B2</accession>
    <name>E3Q5B2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transmembrane amino acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_01023</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089899.1">
        <property type="nucleotide sequence ID" value="XM_008091708.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5B2"/>
    <dbReference type="STRING" id="645133.E3Q5B2"/>
    <dbReference type="GeneID" id="24406388"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01023"/>
    <dbReference type="eggNOG" id="ENOG502QRQD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027816_0_1_1"/>
    <dbReference type="OrthoDB" id="294730at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000039">
        <property type="entry name" value="Neutral amino acid transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF20">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="119"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="165"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="201"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="231"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="296"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="326"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="369"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="409"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="435"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="481"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="8">
        <location>
            <begin position="87"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ25879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="529" mass="57787" checksum="271FC4C1485CC5BA" modified="2011-01-11" version="1">MEKDLRQPGTAPGDKGAAELAFARSDVETGDQTGLSAWFGGRKTKVGPRIAPRQEGLGEHSDGEESPDAILGKQLAEEDGHAIKYRTCSWQKTAGLLFSEYICLAIMSFPWSYSVLGLVPGLILTAVIALIVLYTSLVLWQFCLRHPEVRDVCDIGQMLFWGKKWAWYATAVMFILNNTVSALHVLVGAKYLNTMTESDPVVCRTVVFSIVVTVICWVCSLPRTFDSLSKAGTASAVFTFISVLLATIFAGVQSHPAGYDPRSTYVDASGVTQTGGNPIVTAVPVMSTTFVAGMNAFLNISYTFIGQITLPSFIAEMKDPRDFPKALWAVTIGEIIVFSIVGAVVYAFVGNQYMTAPAFGSLEDVYKKVSFSFMIPTLVFLGVLYASVSARFLFFRLFKGTKHLHEHTIIGWGSWATILLALWLLAFLIAELIPFFSSLLSLMSSLFDSFFGFIFWGLAYFRMRSADNRAGLPKQNKLVDWASMGLNIIIILTGLLFLTAGTYASVEGIIEEFRAGTVGKPFGCASNGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5G8</accession>
    <name>E3Q5G8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glucose receptor Git3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_01079</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089955.1">
        <property type="nucleotide sequence ID" value="XM_008091764.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5G8"/>
    <dbReference type="STRING" id="645133.E3Q5G8"/>
    <dbReference type="GeneID" id="24406444"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01079"/>
    <dbReference type="eggNOG" id="ENOG502RYZC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027149_3_0_1"/>
    <dbReference type="OrthoDB" id="100006at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007189">
        <property type="term" value="P:adenylate cyclase-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023041">
        <property type="entry name" value="Glucose_rcpt_Git3-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR 157-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112:SF37">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR GPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11710">
        <property type="entry name" value="Git3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="28"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="192"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="348"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="377"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose receptor Git3-like N-terminal" evidence="6">
        <location>
            <begin position="120"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF11710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ25935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="548" mass="60313" checksum="22D4B530B2253E86" modified="2011-01-11" version="1">MNETPDHYDSDNSPYSIRPLPPVLRNGLAVVATMGFLSFFTSLGLLVFLTFKLISWHNGPPKLRKEEDQVTKVETPTTANAAFIIPSNWVAATEAAAERAAQENWWRRAINEPPNQFLVLIFNLLLADIQQALAFLLNAKWLTRNSIEVGTKTCWTQGWFVSTGDLASSVFITGIAIHTYVSIVLNKKIPTWIFHTAIAMMWIFVYGTGILTVIITGHGKAEAGLYVRAGAWCWVNSKYQDIRLTLHYLWIFAALILTTMIYFAIFLHLQRIARKSGGVILCCNVAGHESSSSSSNGTSPSDCSVTNWTWKTRSVSDGQRSRIWRPIGLTTVLRRLPDIPDYARQHTFLLYPFVYVICTMPLAAGRLASMAGHNVSLAYFCFAGAMIACNGWMDVVLYSSTRRSIVFSADGPPTQEVGLNTFAFMCNAPPRFGNTTTIISGADPSGNRNCSKWNGKLARKGPKSGSLKGLTVECNESTDSMRGFGMGEGSVMGMAIQCERTTTVSVEEDNTPTPPIRAKFSSCDRKMSNASFLSVDSFQSSGSGSIKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5N0</accession>
    <name>E3Q5N0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ABC transporter transmembrane region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_01665</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090541.1">
        <property type="nucleotide sequence ID" value="XM_008092350.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3Q5N0"/>
    <dbReference type="GeneID" id="24407030"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01665"/>
    <dbReference type="eggNOG" id="KOG0055">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_17_8_1"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18577">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03249">
        <property type="entry name" value="ABC_MTABC3_MDL1_MDL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000913">
        <property type="entry name" value="ABC multidrug transporter SitT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF27">
        <property type="entry name" value="ATP-DEPENDENT TRANSLOCASE ABCB1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="68"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="122"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="301"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="335"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="733"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="782"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="854"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="882"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="966"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="72"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="398"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="740"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="1061"/>
            <end position="1298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="467"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ26521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1303" mass="143123" checksum="5E400EC9613C7A04" modified="2011-01-11" version="1">MNPIKTETASADGVSPVAAGIVDEKNGATQSTAGSNEESTPKAYTRPERQPNVKDYLRVFTYATKWDIFAYFAAGLASIAAGTTLPLMNVVFGQLVDQVNGFGTGNGTTSADDFRKVADRQALYLFALFIARFALNYVNKFGFRMIGIRLSSAIRLHYLQRLFGQTIHVLDSMPAGAAAGTITSTANTLQIGISEKLGVFLEFNGTIWTAIIVAFIYSWSLTLVTASVILFILLVLAVLLPFIIKGHTEMTKAEGKASAVASEAFSSIRIIAACGAEDRIAARYARWVEVARQKGQFTAPLIALQFGLVFFGLFGTFGLAFWYGTHSWVDGRIGGVGEVIIVLMSVMLVVMSLERISTPLLAISKAMVAACEFFTVIDAPHPKTGDLKDPQVSANQNLEFKGVTFAYPGRPHVKVLDDLHLTIEAGKVTAIVGPSGSGKSTIVGLIERWYTLQDQYVIAKTVEKDKTKEAQKKNKKGKEDSDDDEKITPEETGPAVELRGSVTTCGHSLDEIDLKWWRSQIGLVQQEPFLFNDTIFKNVAYGLIGSQWENESEERKRELVKEACQESFADEFIDRLPDGYDTRVGDSGAKLSGDEATSAIDVRGERIVQAALDKVSKNRTTITIAHRLSTIKKADRIVVLKKGKVVEQGTHEGLLENHEGVYYGLVHAQQLSLGDDVDDSDEDNKEEELGTVLNREKSAAKSEVDSTRQKAEVRNRNLFQSFGRLLYEQRHRWILCLSTVVFAACCAAGTPLQAWLFAQVIAVFNPGNTPDKIRSDSNFWSAIWAALAVGIGISYFLMGLAATYLAHFICATYRQQYFDAILFQKTAFFDEEENAQGSLTARVAGDPKQLEELLGLNMAMVFTAIFTIIGAISVAFAFGWKLALVALCVTMPIGIISGYFRFKYEIQFEKMNAAVFAESSKFAAESIGAFRTVSALTLEDTTCARYNELLKNHVTHAFMKARWTSLVFGFSDSVSMACQALIFWYGSRLLISGEYSTQAFFVCFMAVIQGAEAAGQSLSFGPNAAQVTAASNRIINMRESRNQDLLPVVDTIPDTEGGVQIEFRDVHFRYPTRDVSVFKGLNLAIEKGQFAALVGASGCGKTSIISLMERFYDVQKGAILCNGKNISDVNIYEYRKQLSLVAQEPTLFQGTIRDNILLGVDENSVTDEQLHRVCRDASIHDFVASLPEGYNTDIGSRGVSLSGGQKQRVAIARALIRDPHILLLDEATSSLDSESEKLVQAAFERAGKGRTMLVVAHRLATVQNADIIFVLGEGKLLEKGNHVELLKKKGVYWHMCHSQALDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5N5</accession>
    <name>E3Q5N5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sec1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_01670</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the STXBP/unc-18/SEC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090546.1">
        <property type="nucleotide sequence ID" value="XM_008092355.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5N5"/>
    <dbReference type="STRING" id="645133.E3Q5N5"/>
    <dbReference type="GeneID" id="24407035"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01670"/>
    <dbReference type="eggNOG" id="KOG1302">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016678_3_1_1"/>
    <dbReference type="OrthoDB" id="10262287at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.830.10">
        <property type="entry name" value="Syntaxin Binding Protein 1, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043154">
        <property type="entry name" value="Sec-1-like_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043127">
        <property type="entry name" value="Sec-1-like_dom3a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001619">
        <property type="entry name" value="Sec1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027482">
        <property type="entry name" value="Sec1-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036045">
        <property type="entry name" value="Sec1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043155">
        <property type="entry name" value="VPS33_dom3b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11679">
        <property type="entry name" value="VESICLE PROTEIN SORTING-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00995">
        <property type="entry name" value="Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56815">
        <property type="entry name" value="Sec1/munc18-like (SM) proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="596"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ26526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="660" mass="73704" checksum="DF7A977AF09EA43A" modified="2011-01-11" version="1">MAPRAGFNTDQIKDKARKDLLYLLEAVRGKKNLILERSLAGPIGTIVKVTTLQEYGVDKFFFLENKNADTSQRNVIFIARGECARHAQTIAEQIRRLQRESQTGHDFHIFWVPRRTLVSDKLLEEAGVLGDVNISELPLYFFPLEKDVLSLELDESFRDLYLSKDVTPSFLLAKALMGIQQDHGLFPRIIGKGDNAKRVAELLARMRQEILAGEDAAETNRGSLSPSILTESAIIIDREVDFVTPLLTQLTYEGLIDEVFGIQNNQAEVDTTVVGAPSQSSTTSAQARKRKIQLDSSDKLYEQLRDTNFAIVGSLLNKVARRLQNLQKDYEGRNSHKSIAELKDFVSKLPGYQAEQQSLRIHTGLAEEIIKYTRTDQFKGLLEAQQNLAAGADPSSQFDAIEELIARDTPLPEVLRLLCIYSCISGGIKPKEFDHFRRLILEGYGYQHILTLNNLEKLQLFLSRSSPLAEMIPMSGAGGNNTGTKTNYTYLRKLLRLIVDEVQEDDPNDIAYVYSGYAPLSVRLIQCVLQKQYLLKVTRGNGVSGAPGGSAVQGWHGFDEAVKHVRGQTFYELQKGEEKAMKARALLSGGAEKQTVFVVFVGGITFTEIAALRFIAKQEESRRNIIICTTSIINGDRMMDAAIEKESFARDNVKPPSPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q630</accession>
    <name>E3Q630_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">NUDIX domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_01422</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090298.1">
        <property type="nucleotide sequence ID" value="XM_008092107.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q630"/>
    <dbReference type="STRING" id="645133.E3Q630"/>
    <dbReference type="GeneID" id="24406787"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01422"/>
    <dbReference type="eggNOG" id="KOG3069">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040940_1_1_1"/>
    <dbReference type="OrthoDB" id="206213at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010945">
        <property type="term" value="F:coenzyme A diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015938">
        <property type="term" value="P:coenzyme A catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03426">
        <property type="entry name" value="NUDIX_CoAse_Nudt7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045121">
        <property type="entry name" value="CoAse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12992">
        <property type="entry name" value="NUDIX HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12992:SF24">
        <property type="entry name" value="PEROXISOMAL COENZYME A DIPHOSPHATASE NUDT7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="8">
        <location>
            <begin position="170"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="69"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="423"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="17"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="69"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ26278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="452" mass="49350" checksum="16379BAD50F85BBB" modified="2011-01-11" version="1">MSQAAATDPSPAPTSPPSFSEDAAAATTGTTTTATASPALQQQHQDHQLDEATPLTAQDVHEITAHLAAAAKHPSAATSAVSPSPAAGVTAATTPATPSSASSKRGDIDDSTANPNPEGVLILDDDDEEVTSYWDAEAMAPLNPVSAAAISRLRRYVPPAFPLWDRLPVSRRAAVLILLYADRRGDLRVVITMRAASLRSFSGHAAFPGGKADTIQETPYEIARREAWEEIGLPMDDARIPKPFKIEPLCYLPYNLARTELVVRPCVAFLHADEEPDENPSPLVEERMIPRLDAKEVAAVFSAPFQNFLRARDAEPHGNRALPPGHWYDGSWIQWKDHPWRVHNFYVPVDDQRVTTPGNAMEADHPQSNLAEKLEEDKVGRFKVWGLTAHMLVDAARIAYGKEPEFECNSHFGDEEIILQAEREGSLVDKKRKRDEAAATGTTEEKAEPAKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6M3</accession>
    <name>E3Q6M3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine-threonine protein kinase 19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_01615</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the STK19 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090491.1">
        <property type="nucleotide sequence ID" value="XM_008092300.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6M3"/>
    <dbReference type="GeneID" id="24406980"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01615"/>
    <dbReference type="eggNOG" id="ENOG502S7IU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036328_0_0_1"/>
    <dbReference type="OrthoDB" id="3980126at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046579">
        <property type="term" value="P:positive regulation of Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018865">
        <property type="entry name" value="STK19-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15243">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15243:SF0">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10494">
        <property type="entry name" value="Stk19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="32"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00093458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ26471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="415" mass="44538" checksum="670A42B6E7E252B6" modified="2011-01-11" version="1">MSSLRSILSGGRVRKSKPKPKVTVSASPRKNSGTSSSRTGGSSVTAIRKKPVRADAGFDDDDGGDDFFHDRLDDVGLVAALATDMSLRDVVQAIKHTRNRMFGPVPTEAAGMKSTRIAEVLSFRKAVPGIVTVSHLHALLASPTAVEREVAELQRCGAIRKIYVQRRGGLGEALIETPELEEMIAQSAGLDEEAKMAFTKFLRENPLAQTMPRSACGHKQADALVRAGFLTANVHPQHVNTPLMNLHLRPEDRGSLMSIEAVSRAASGSFEAVGGQGAVHAAGGGGGGGGALRRSRADDVSCSGDEFTIAVPGNGSFLKLATAAVEHVTQLLSKSQYREMPVSMLRERWEGGVARDEARLAKRARGEFAGVLPGRTKRWREFYGLEFHWVLEEAVGAGHVEVFETRSVGRGVRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q708</accession>
    <name>E3Q708_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_02466</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090666.1">
        <property type="nucleotide sequence ID" value="XM_008092475.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q708"/>
    <dbReference type="GeneID" id="24407831"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02466"/>
    <dbReference type="eggNOG" id="ENOG502T5DR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1948676_0_0_1"/>
    <dbReference type="OrthoDB" id="10402811at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ26646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="129" mass="14736" checksum="7AD389E14174D34B" modified="2011-01-11" version="1">MGYHFDPLVATYISIVQSNTLPMSIRIRHVFKHRTSTNVAYLITIPITAFIERPRIEDHASNADEQRARLFPGVQDVSFCSSMRLVVNVKMADVWMRCVGASPVKKNTTHLKTLLDAWRKNIEQDTAHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7J2</accession>
    <name>E3Q7J2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Adhesin protein Mad1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_02650</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RBT5 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090850.1">
        <property type="nucleotide sequence ID" value="XM_008092659.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7J2"/>
    <dbReference type="STRING" id="645133.E3Q7J2"/>
    <dbReference type="GeneID" id="24408015"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02650"/>
    <dbReference type="eggNOG" id="ENOG502RZBR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013457_0_0_1"/>
    <dbReference type="OrthoDB" id="5431405at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180185" evidence="10">
        <location>
            <begin position="20"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="11">
        <location>
            <begin position="440"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="395"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="594"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="409"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="594"/>
            <end position="606"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ26830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="657" mass="66946" checksum="BAB7249899D4E6C7" modified="2011-01-11" version="1">MKNSVALLALAAGVSQVTATGWNKFPSFTCPQNTDNQCDDKQKSGFSWGDLSTGSFSNYGGFDFKGWTCESDFSKRDLLAPRTFTKGKVISGSCGQKKETSPSFGCGSAPGGPDKFSISHFDVTVEFDCDLEFHYDMPDGSNCKQRSPCSKSGTTVTNSQCGGAKNVTIVYPSQPSKPKSTCGVGIHTIGFDCSPAETPKPPKTTVSQALPSATTLSTQIQVPTTPAGIPTVSKPVEETKPATTAPVKETVSVPVPIQSETTPVVLPSISVPVKGSTTAAVVPSVTTPAEQTPVISKPVEETTPSQFPTIPVPAPVNSTKPALIESTPAVVTPVVPETKTTVYDTTSTIYTTRVETVTSCAPEITNCPANSHAVVTRTVPLTTTVCPVTETIVHTPGPAPTKPAGQPPKGVSSEKPVGSVPVVKPSGTKPAGPIETLPCPDVVPQCLSSWMWSTGCAANSDANCYCPDAQFVENIFSCIYAYGASDDIISKATLFFQGICAPHIPQNPAIVTAPATITTALTVGVEKPAPTNPADITTVVIDKTVVVPCVTGGTTIPGSSTTATIKTTLVVPQVSFATNSASDVVPVPIKAPTAPAGGAGPSGVPAAPYPTGPAAGASKPAGTGGLKPTPTGVVTAGAGKASFGIGAIVAIAALAAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7K2</accession>
    <name>E3Q7K2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_02660</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090860.1">
        <property type="nucleotide sequence ID" value="XM_008092669.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7K2"/>
    <dbReference type="STRING" id="645133.E3Q7K2"/>
    <dbReference type="GeneID" id="24408025"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02660"/>
    <dbReference type="eggNOG" id="ENOG502RYMZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005679_13_5_1"/>
    <dbReference type="OrthoDB" id="5819582at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050879">
        <property type="entry name" value="Acyltransferase_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028">
        <property type="entry name" value="ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028:SF126">
        <property type="entry name" value="ACYLTRANSFERASE 3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="247"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="349"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="400"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="475"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="domain" description="Acyltransferase 3" evidence="2">
        <location>
            <begin position="88"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ26840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="518" mass="58503" checksum="2E0A79C11A8F8DEB" modified="2011-01-11" version="1">MISLAVRSVRGALVRLSPSSHSYPYAPLSNANGHSEPSLPSGSTPKPQPTTILARLIAILFFLLPSFLQRKLRLNDSKNHRRRLYSTSWLDGLRGTASLIVFICHYSGPNFGWYLARPYGIPQENDTAASSPLQLPFLRVIYSGKPMVHIFFVISGFVLSLKSLQQARKHNYDGLHRTLSSSVFRRGFRLFLPTTASTFIIMIMIRLGWMGQPLPTLWEQLIDWKNALWRITFSWQWDITQFLPYDVHLWTIPIEFSNSLLLFVTLTGVSRMKTCLRLTSVLTIMAYCLRCGHWAAFEFFGGMVLAEIGLIQEARRERVAAALQNKEEESDSAALDGVSSSCSKSVKTVIIKAFLIGNLIFGLFVAGWPDEVNDITPGIAPLFHNTMEPYFTMGGDLVAFPWYALGAIQIVAALQQVTVLQNLFITPLAQYLGDISYALYLVHGPVLDVLEHRWMPYVWTLVGSREEAGMWGRMVAWFIGLIALGVPTIWCSDIFWRTVDVKTVELSRWIEAQCVRDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7W8</accession>
    <name>E3Q7W8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_02151</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ26980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091000.1">
        <property type="nucleotide sequence ID" value="XM_008092809.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7W8"/>
    <dbReference type="GeneID" id="24407516"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02151"/>
    <dbReference type="eggNOG" id="ENOG502T4KC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1970387_0_0_1"/>
    <dbReference type="OrthoDB" id="4849847at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178273" evidence="2">
        <location>
            <begin position="20"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="53"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ26980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="127" mass="13286" checksum="E9ED76F3CEF54F62" modified="2011-01-11" version="1">MSAIRPSSSALLLLGGVATLPGAATVRSRFPQRSPPSDSADAELGYMQQPLGPVSSSSTRTASPTAVAQKTAPRSSSATATAVQIVTMATVHTRPQAWDESDAGYRPKSAREMVVVILGRNRKYSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q843</accession>
    <name>E3Q843_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Kelch repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_02226</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091075.1">
        <property type="nucleotide sequence ID" value="XM_008092884.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q843"/>
    <dbReference type="STRING" id="645133.E3Q843"/>
    <dbReference type="GeneID" id="24407591"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02226"/>
    <dbReference type="eggNOG" id="ENOG502SMKA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012508_3_1_1"/>
    <dbReference type="OrthoDB" id="540004at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019760">
        <property type="term" value="P:glucosinolate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47435">
        <property type="entry name" value="KELCH REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_5G12780)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47435:SF4">
        <property type="entry name" value="KELCH REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_5G12780)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180212" evidence="5">
        <location>
            <begin position="23"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="483"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="449"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="531"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="578"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ27055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="595" mass="63588" checksum="724B38A39326F8A5" modified="2011-01-11" version="1">MVSRGWLVALFAAAHLSPVCSADDADDAGALDVPPVANFLRRVFARSSVIGNWAYFDGGEVSQHIGNGQNTSRPSSPLSSTLSIDLSKSWKPADVEIKQTQKFAPKMNRQAVFTDASSNSFYIWGGHTSYLADPPSPRLWKFSADGSGGGSWSTEIKPGHDLFTRLTRSQGAAYVSTPDSGFYFGGFSSGSADPNPKGPVPGFLEFNYTATDQAWKNHTVAPYSTSGNVVGASAHYVPSFGPNGIVMMFGGASHVIGAGQSNSNVGWLGFDTIYVMEPLSKRWYSQKTSGNAPGARMWHCTAGAVSQNNTYEIFVFGGSNTANKETYDEVYVLSLPGFVWIKADYAPSSPRDCMSCVVAGRRQMVTFGGVDRMRWNDNSTNFFRDPDPFPQGVGVFDLTDLKWKDEYDADASSYDSPEAIKAWYNEGNIASVQYSDAVARLMSSGTSGSAFFSGSGSGPDSGSDPGSDPAPGDSGSGSVNAGAIAGGVVGGVAGIALISLAAFYLMRRRKHKRAPAQESGGAVEDPIYPQEMEHSYSPNPPPTSSVAPSELHGEYRDHSPYSMGEVPKMMQPPEMDAQDPRYGHAAELDASETRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8W7</accession>
    <name>E3Q8W7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11 12">Endo-1,4-beta-xylanase</fullName>
            <ecNumber evidence="4 11 12">3.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">GLRG_01976</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11 12">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-xylosidic linkages in xylans.</text>
            <dbReference type="EC" id="3.2.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11 12">Glycan degradation; xylan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11 12">Belongs to the glycosyl hydrolase 11 (cellulase G) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.8" evidence="4 11 12"/>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091501.1">
        <property type="nucleotide sequence ID" value="XM_008093310.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8W7"/>
    <dbReference type="GeneID" id="24407341"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01976"/>
    <dbReference type="eggNOG" id="ENOG502S2KQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052631_3_2_1"/>
    <dbReference type="OrthoDB" id="2115822at2759"/>
    <dbReference type="UniPathway" id="UPA00114"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031176">
        <property type="term" value="F:endo-1,4-beta-xylanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013319">
        <property type="entry name" value="GH11/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033123">
        <property type="entry name" value="GH11_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001137">
        <property type="entry name" value="Glyco_hydro_11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46828:SF4">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46828">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00457">
        <property type="entry name" value="Glyco_hydro_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00911">
        <property type="entry name" value="GLHYDRLASE11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51761">
        <property type="entry name" value="GH11_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11 12" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9 11 12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 11 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 11 12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0732">Signal</keyword>
    <keyword evidence="5 11 12" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005344615" description="Endo-1,4-beta-xylanase" evidence="13">
        <location>
            <begin position="20"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="GH11" evidence="14">
        <location>
            <begin position="31"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="11">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EFQ27481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="222" mass="23461" checksum="EDC51E1B7387C176" modified="2011-01-11" version="1">MVSFTQLALAASVIVQAFASPIASPDAPDFELSSSTSLARRQDYTQNYKTSGNVNFSPAGNGYSVQFSGAQDFVVGKGWTTGSKTRSVTFSGSTSANAGTVLVSLYGWSTSPLVEYYVQEYSNGQGAAQGTKVGSLTSDGSEYDIWKHTQVNQPSIVGTTTFTQYISVRKSGRPNGGTITFANHVAAWQKLGMNLGTMNYQTISTEGWGNAAGSSKYTVSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8X2</accession>
    <name>E3Q8X2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aldose 1-epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_01981</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldose epimerase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091506.1">
        <property type="nucleotide sequence ID" value="XM_008093315.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8X2"/>
    <dbReference type="STRING" id="645133.E3Q8X2"/>
    <dbReference type="GeneID" id="24407346"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01981"/>
    <dbReference type="eggNOG" id="KOG1371">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031753_3_0_1"/>
    <dbReference type="OrthoDB" id="274691at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004034">
        <property type="term" value="F:aldose 1-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033499">
        <property type="term" value="P:galactose catabolic process via UDP-galactose, Leloir pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09019">
        <property type="entry name" value="galactose_mutarotase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018052">
        <property type="entry name" value="Ald1_epimerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008183">
        <property type="entry name" value="Aldose_1/G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047215">
        <property type="entry name" value="Galactose_mutarotase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10091">
        <property type="entry name" value="ALDOSE-1-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10091:SF0">
        <property type="entry name" value="GALACTOSE MUTAROTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01263">
        <property type="entry name" value="Aldose_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00545">
        <property type="entry name" value="ALDOSE_1_EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ27486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="340" mass="36567" checksum="31D5A6A212FFA87C" modified="2011-01-11" version="1">MADAPFEFLPLGAILQSFKVKGVNIVQGFPTQELYEQHNSPYFGVTVGRVANRLDSAQIKSLNGGKTYKLAANDEGNNLHGGLKPWSSLVWDGPKPVGVREIPGVEGLEGGESVEFSLTSPDGDEGFPGTVKAKVVYTAGTQKVDGKEISVLGIEYEAQLVDGADETAINMTNHSYFNLTGDETFAGTMATLATNSHLPRKNGIPTGGPVPFPGIEGGKPFELGVEGPEVDDCFVVTEKPGSVPIDTRKEALKLHVHARHPKNGINLEVLSTEPAFQFYTGNGINVPAVEGAPARGKRSGFCVEPSRWVNAINVPEWKDQMLLKKGETYGTRIVYKAWSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9E2</accession>
    <name>E3Q9E2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_01816</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091341.1">
        <property type="nucleotide sequence ID" value="XM_008093150.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9E2"/>
    <dbReference type="GeneID" id="24407181"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01816"/>
    <dbReference type="eggNOG" id="ENOG502SRT8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099112_0_0_1"/>
    <dbReference type="OrthoDB" id="3636092at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ27321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="172" mass="18452" checksum="A915C8B687B2A2A8" modified="2011-01-11" version="1">MASLVFQLASALPTPKAHIKVAPDVQSGHPEAYAVFMRAPRLILDDVARKRQAVPGDGQPDPNRAPITPDNIFVLQCPDAGFLGDCISFGAPPGRCVGYSSFNTSQAFLDKYDNQTSSLSTNTGGQCQFYKFTGCGEKGDDRGVALSYKFNLGVADIGYGGDYDNQISSWKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9Q6</accession>
    <name>E3Q9Q6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">GLRG_02738</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>5-dehydroepisterol + NADPH + O2 + H(+) = ergosta-5,7,22,24(28)-tetraen-3beta-ol + NADP(+) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:33467"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:18249"/>
            <dbReference type="ChEBI" id="CHEBI:52972"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.14.19.41"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:33468"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="11">Steroid metabolism; ergosterol biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091614.1">
        <property type="nucleotide sequence ID" value="XM_008093423.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9Q6"/>
    <dbReference type="STRING" id="645133.E3Q9Q6"/>
    <dbReference type="GeneID" id="24408103"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02738"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023517_0_0_1"/>
    <dbReference type="OrthoDB" id="1372046at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000249">
        <property type="term" value="F:C-22 sterol desaturase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016125">
        <property type="term" value="P:sterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11082">
        <property type="entry name" value="CYP61_CYP710"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000021">
        <property type="entry name" value="Cytochrome P450 61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24286:SF228">
        <property type="entry name" value="C-22 STEROL DESATURASE ERG5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24286">
        <property type="entry name" value="CYTOCHROME P450 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="13 14" id="KW-0349">Heme</keyword>
    <keyword evidence="9 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="8 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="binding site" description="axial binding residue" evidence="13">
        <location>
            <position position="478"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00051023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EFQ27594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="533" mass="59678" checksum="F621D787B29E1B71" modified="2011-01-11" version="1">MDSNATAFTSVLANAKLGNVNIPPQVDYIIDKMANAGGWTILFTLLALAVAYDQISYITSKGPIAGPTFKMPFIGPFLESVNPKFSEYKAKWASGPLSCVSVFHKFVVIASTRDMARKVFNSPGYVKPCVVDVAHKLLGPTNWVFLDGKPHVDFRKGLNGLFTRQALASYLPGQEAVYKQYFQEFLQTTKDAGGKPVPFMPCFRDLMTAVSCRTFVGHYISDEAVRKISADYFLITEALELVNFPVILPFTKPWYGKKASDMVIGEFAKCAAKSKVRMAAGGEVTCIMDGWVKSIVDSRRWREAEASGSTEGLVKPVPLLREFSDYEIAQTVFTFLFASQDATSSAATWLFQTMAQRPDVLDRVREENMKVRNGDRHAELNMDQLESLTYTRAVVRELLRYRPPVLMVPYVVKKPFPITPEYTVPKGAMVIPTVYPSLRDPEVYDRPDEFDPERYYTGDAEEKGAKNFLVFGTGPHYCLGQTYAQLNLALMVGKASVMMDWVHHPTPKSEEIKVFATIFPMDDCPLTFTERVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9W3</accession>
    <name>E3Q9W3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_02795</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091671.1">
        <property type="nucleotide sequence ID" value="XM_008093480.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9W3"/>
    <dbReference type="STRING" id="645133.E3Q9W3"/>
    <dbReference type="GeneID" id="24408160"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02795"/>
    <dbReference type="eggNOG" id="KOG1721">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006466_0_0_1"/>
    <dbReference type="OrthoDB" id="427030at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001164">
        <property type="entry name" value="C2H2 finger domain protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF11">
        <property type="entry name" value="ZINC FINGER PROTEIN YPR022C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="99"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="129"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="156"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="625"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="8"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="275"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="325"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ27651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1037" mass="115101" checksum="81171554BA8DF005" modified="2011-01-11" version="1">MASILPAHSTNFKPSISLSSTSPATMASKHDPRASPQRYIKQEHEPGRGRPRQISEDKDVDIMDDDEADGDEGKAGSSNSDGGPARKRRRSRKGLDKKFECPQEGCGKSYSRAEHLYRHQLNHTPKQIYACDFPECSRTFVRLDLCNRHRDRHTAKGSALNRKDSLMSHLSPTADRPPFPLAGSASPETSRPGNGFANLRQAQMQYQPPKDVSGSPFAQATNTPPGYPMGAHPGSMNNYMHHDNGYGGLQAHRPPQQSPNGPGPTVQANGAYMSPTPSQNGYHTQPHSAPQPVTYTNQQNFPAFNLPPSDFPNGAGSGPREGQTYAPTTSAEYSEQGHTQQSGEMMLLDQMSMPGTIPVFGSDSILSKSPYVTIPEDFVAYLFNTQQGEGSPMGHMVAPGYVNNYGEVQNSYSVPYVGTDGVPAGYFPSGPQQVMAVNNLLDQNLPEATISEEKSQEIYDFINQRFHENDQAPALRQRDSILEGDRSDGDHMLSKRMMQAYIGSYWVHFSDQIPILHKPTFSPDRTPNLLLLAMMTIGAACLDKTHGQKVTKAGAQLSNFLAWHLRWEIFMDPNFRPPAKLWVFQTLLLLELYEKMYSTRELHERAHIHHATTITLMRRGRSLIGKSSLDSPPNPRDDKTNGSRHSSTSGVAHTADEWWNHWITNESTRRAAFAAFVIDSIHATMFGHSTVMVTHEMRLPLPCEDALWKATSGAEVGRIESNLLSNGVKPLSFLEGLKRTLSGQGVQTNPFGRMVLMAGLLSVSWHMNQRDLQVNVLGGGVSQALGGRDKWRGTLTRAFDAWKEDFDKSLTRNEGSSDPYRYDSAKKNDANVVFESRTVLHHLAHMAMHVDIVDCQIFARAKRLLGRAIGQQDLNSAQRRMRDLWAPSAKARDATFYALKFLKSVLVPDANHLPQANGYKYDEPYTARDDVLLNRPWVLYFAALVVWCYGFALEGPCPGTPVPGTKQEQVHQMREYLTKYGGANSPDDLKVMKGVNTNTALLLVLKDSFGTTRWELLHEGANLLNNCLQLNTGAATM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>E3QA14</accession>
    <name>E3QA14_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Eukaryotic aspartyl protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_02846</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091722.1">
        <property type="nucleotide sequence ID" value="XM_008093531.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QA14"/>
    <dbReference type="STRING" id="645133.E3QA14"/>
    <dbReference type="GeneID" id="24408211"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02846"/>
    <dbReference type="eggNOG" id="ENOG502T0DX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009988_1_0_1"/>
    <dbReference type="OrthoDB" id="5233646at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180264" evidence="4">
        <location>
            <begin position="18"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="450"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="5">
        <location>
            <begin position="39"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="745"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="802"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="747"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="802"/>
            <end position="814"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ27702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="846" mass="91132" checksum="7FFD4296A35AE0A4" modified="2011-01-11" version="1">MLSATLITSVLVARVAAESQSAVALTPSNGWYGVDGNWSAIELQVGTPGQTVNVLASTSLSEFWVIGAGGCDANDTLCNSARGGVFDVADSKSWSSLGTWQLGFDYLNNGASGDYGLETLSATLLDGDQVLSMDNIITASINATSYYLGFLGLGVTKGSFGNQVAESPLSQAVKQHGRIPSYSYGYTAGAHYMGVSGTPCSLTLGGYDESRFVQHNNEFSLDPNDGLPHALVRAIEVTTGQDKVLPGGWNTSTRILSDMSTSFIAMIDSSTPYLWLPDAICDQFAQAFNLTYNSTLELYTLTDGQYTDFKHASSYSFTFTFTSQDNNDDFGHPLTVPGVVNITITAAAFAQALRYPFQSDAIQYGDPAVPYFPLRRASSLTDTFIIGRSFLQEAYLITKYDTGVFSLHQALFPDEPLESVQLHNVAQPNNSPFPPSSPVNLHRGLSTAQMGGIAAGAIAGCVIMLTCWCLYRRKKKKSRANIRALEDAKDGASSIMPEPPKRPVTMVFTKILGKKKAKRASAHEVMGSSSHPAEVGADANHALYELPVSTNPAELGGDDCKSALSQTDFEAGGRYSMGPFDAGTRTVEIRLQSPVPAYSPPETPAAFPPSEKLLRDTSSITTSRPEEYWVLPSVSPTSVRGSLPSPLSFRSGEWTNHSSDLLSPWMDGQSFHGPAFTDNNAGNPLFYPVSPESEVFTSCTANSSNIPPPIPVSVLPTSPLPTHRRAPPMEFTNVICLGPLPDNITLPAPPARPPRPPPPAPPPVIPDVAVPEIVAANRASTDTLGSNWTEFEEELIAQEITRQESLREQARNQDLESGSPRSLHRLDGTELIHIPQPAERRYSWEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QA74</accession>
    <name>E3QA74_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SigF-like NTF2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_02906</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091782.1">
        <property type="nucleotide sequence ID" value="XM_008093591.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QA74"/>
    <dbReference type="STRING" id="645133.E3QA74"/>
    <dbReference type="GeneID" id="24408271"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02906"/>
    <dbReference type="eggNOG" id="ENOG502S534">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079426_0_0_1"/>
    <dbReference type="OrthoDB" id="2344312at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057514">
        <property type="entry name" value="NTF2_SigF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35393">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35393:SF1">
        <property type="entry name" value="SNOAL-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24840">
        <property type="entry name" value="NTF2_SigF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="SigF-like NTF2-like" evidence="2">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ27762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="223" mass="25946" checksum="C2B2B9FE991AD461" modified="2011-01-11" version="1">MDHPVKEIKTVIRDLVQGSPEKQLNALYSNFAEDAAFTHPFCHVPSFGNTNIPFFFTVNSRWLILMVYRWYRILSPNIDMEIESCVQDQKTNILYVKMRQNFRLWFVPFYKAPVDFVVVLRLETRTVDANGNLLPRGQGDPNTVGNRQRQFIVSQEDHYQVGEWLKFLVPFFGYWAWHVWTLFATALCVVGAFFGYPLTLLFQQFAVNNSTNGTGSSQEVKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAX5</accession>
    <name>E3QAX5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein disulfide-isomerase</fullName>
            <ecNumber evidence="3">5.3.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_03157</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Catalyzes the rearrangement of -S-S- bonds in proteins.</text>
            <dbReference type="EC" id="5.3.4.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the protein disulfide isomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.3.4.1" evidence="3"/>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ28013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092033.1">
        <property type="nucleotide sequence ID" value="XM_008093842.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAX5"/>
    <dbReference type="STRING" id="645133.E3QAX5"/>
    <dbReference type="GeneID" id="24408522"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03157"/>
    <dbReference type="eggNOG" id="KOG0191">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038617_1_1_1"/>
    <dbReference type="OrthoDB" id="10264505at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00238">
        <property type="entry name" value="ERp29c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02998">
        <property type="entry name" value="PDI_a_ERp38"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000032">
        <property type="entry name" value="Protein disulfide-isomerase A6 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1150.12">
        <property type="entry name" value="Endoplasmic reticulum resident protein 29, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011679">
        <property type="entry name" value="ERp29_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036356">
        <property type="entry name" value="ERp29_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051063">
        <property type="entry name" value="PDI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005788">
        <property type="entry name" value="PDI_thioredoxin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01126">
        <property type="entry name" value="pdi_dom"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45672:SF11">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE C17H9.14C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45672">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07749">
        <property type="entry name" value="ERp29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47933">
        <property type="entry name" value="ERP29 C domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180361" description="protein disulfide-isomerase" evidence="10">
        <location>
            <begin position="19"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="11">
        <location>
            <begin position="7"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="11">
        <location>
            <begin position="131"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ28013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="371" mass="40056" checksum="B4D89DC47C41505E" modified="2011-01-11" version="1">MVVLKSFVLGALAATVAAKSAVLDLIPSNFDDVVLKSGKPTLVEFFAPWCGHCKNLAPVYEELATAFESSKDVQIAKVDADAERDLGKRFGIQGFPTLKWFDGKSDKPAEYKGGRDLDSLTAFITEKTSVKPRKKYTPPSAVNMLSDETFKTTVGSDKDVLVAFTAPWCGHCKSLAPVWETVAQDFSLDDGVVIAKIDAEAENSKGTAAAEGVTSYPTIKFFPKGSKEGELYTGGRSEADFIEFVNQKAGTNRTPGGALNAVAGTIAALDKIVAKYTGGTSLSEAAAEAKKEAETLKDKAQYKYAEYYVRVFDKLNKSDGYALKEVARLEGILSKGGLAPAKRDEITSKTNILRKFLQKVEEKVAGEKEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBF6</accession>
    <name>E3QBF6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Zinc knuckle domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_03439</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092315.1">
        <property type="nucleotide sequence ID" value="XM_008094124.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBF6"/>
    <dbReference type="STRING" id="645133.E3QBF6"/>
    <dbReference type="GeneID" id="24408804"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03439"/>
    <dbReference type="eggNOG" id="KOG4400">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_351598_0_0_1"/>
    <dbReference type="OrthoDB" id="7608935at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031499">
        <property type="term" value="C:TRAMP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071031">
        <property type="term" value="P:nuclear mRNA surveillance of mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071039">
        <property type="term" value="P:nuclear polyadenylation-dependent CUT catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071036">
        <property type="term" value="P:nuclear polyadenylation-dependent snoRNA catabolic process"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="P:nuclear polyadenylation-dependent snRNA catabolic process"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="Zinc finger, CCHC-type"/>
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        <property type="entry name" value="TRAMP_AT-DNA-binding"/>
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        <property type="entry name" value="Znf_CCHC"/>
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    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46543">
        <property type="entry name" value="ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 7"/>
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    <dbReference type="PANTHER" id="PTHR46543:SF1">
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
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    <proteinExistence type="predicted"/>
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    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
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    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="9">
        <location>
            <begin position="537"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
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            <begin position="1"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
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            <begin position="342"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="640"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="37"/>
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        </location>
    </feature>
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            <begin position="49"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
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            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
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            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
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            <begin position="145"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
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            <begin position="178"/>
            <end position="197"/>
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    </feature>
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        <location>
            <begin position="201"/>
            <end position="210"/>
        </location>
    </feature>
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            <begin position="211"/>
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            <begin position="379"/>
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    </feature>
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            <begin position="668"/>
            <end position="680"/>
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            <begin position="685"/>
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            <begin position="741"/>
            <end position="761"/>
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            <begin position="768"/>
            <end position="781"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ28295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="781" mass="84359" checksum="C144E60BE2BD76AC" modified="2011-01-11" version="1">MDASGSAEAKSLLPGGEDDTQQASKKRPLEDVEQGDIQISGSPQSNKAESPEPEAKRAKTDVLNQQRAQKDTKGSESAEEGELEEDGEVKSSESESEDMAGSQSDGSRASRARSKASAASREADAGVRRTTRSMSEAANGPAHTGWNQGITSQIRTSLGGSKAKEALAPAKEAAISKEATSQPVPSAAESEQIQLAQPAQKEGKLTRKEQQQQQRAEAAALKKQKAQEPQKNIFVYAPGLTFFQPNKKTILLPKGNNLSKTVWKSKFKSWCQSFVSHNTEQSSLLTADIVVAALQDYIATRAHWSKKKHTTAATAEARTPEMKNEIAVYLATILKDDSLLPGSEESPMVIDDNDDEADNSVQEVSRPAGDIASAVPETQGEHDSTAEDPDQSYKDDTGASMEVEQTEPGPPVMTEEEDLAQQRKYFPGLPESVEICVYCASVGHNSAACSKTACKFCQQPNHFSWNCPTRERCTKCRQLGHGKAQCTEKLVHLDEEGMECAMCSAQDHLEDECEALWRSYKPQNGLIKRVKVFPAFCASCGAEGHYSSDCALRGDRPRNHTWSLKNRSLYVDKNALEGPISNFASQPQNPKFPLQIKGSAAKRNHIFYPDSDGSEEGEFIGQKVKPRAPLGNIQLSTNLQINTGNFGAPPQTQQNGRGQQRGGWSAQPPLPPGPPPPGPSPGSYSRMSRSFNNQSRPPPPNGGGVRGGGLPPKPPAPQSQQHGYHNAGPPSRPNPPKKQRNQSGSSHAGSSQQQQQQQQQQNGGGPGPRRRAKARRGGKQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCI9</accession>
    <name>E3QCI9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_03721</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092597.1">
        <property type="nucleotide sequence ID" value="XM_008094406.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCI9"/>
    <dbReference type="STRING" id="645133.E3QCI9"/>
    <dbReference type="GeneID" id="24409086"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03721"/>
    <dbReference type="eggNOG" id="ENOG502S728">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019419_0_0_1"/>
    <dbReference type="OrthoDB" id="2351940at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        <location>
            <begin position="411"/>
            <end position="450"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
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        <location>
            <begin position="107"/>
            <end position="123"/>
        </location>
    </feature>
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        </location>
    </feature>
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            <begin position="183"/>
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        </location>
    </feature>
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        <location>
            <begin position="421"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ28577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="560" mass="63503" checksum="D6D5F7332D073751" modified="2011-01-11" version="1">MSSQRPNPSQNSQRRDNNDYPPLPPHRRLPPLPPLPADHVIHPPQPPRHPWEPEPYTTQDQTESYLHLRRHMADRNFQAEYDELVGNSLNGFTAFMSAAQDDFGFSRDSTQNRSQASNLLDTPQNDQRDNDDVRRNPLQLPPVFGYRAVRSINGRQRPEGTEDDVEAVRALWNRRAQYSSSPFSPPRMPPNMSPPNLSPLPPSEEYHEGNRRVKRRKLDSERASQSFRGFRYGRYGQVEPGQLKMEIVSCDGGLYENASLHAYENILKDDKTVYCTQSNRCNIILRHQGATAFTLKELVIKAPASNYSSPVREGMVFVSMDQDELLKRTAQYEIQYAPLRSSRSSATRALAPIISIRHHEDGTTVTRTHTRQRRLYSLGHDEEENGPRTAQIPAEFTTHLPPFNITTECSYEETDDEENPRVPVNRRAPNRIGALPFESDSSDDGNPFASDEYGFEDFPFTSRRRDASDMSLAEAVEATQVATQEAVRAVGGELMAPHAKFFIEKDKSKCTIRFDPPVSGRFILLKMWSSSRASGSNIDIQAVLATGFAGPRYFPSVELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCP7</accession>
    <name>E3QCP7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_03779</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092655.1">
        <property type="nucleotide sequence ID" value="XM_008094464.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCP7"/>
    <dbReference type="STRING" id="645133.E3QCP7"/>
    <dbReference type="GeneID" id="24409144"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03779"/>
    <dbReference type="eggNOG" id="ENOG502RJXY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_683355_0_0_1"/>
    <dbReference type="OrthoDB" id="4586300at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="342"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="290"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ28635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="397" mass="45324" checksum="FA8B5245F0B52F02" modified="2011-01-11" version="1">MPDNDSPDNFFVRFKQKVDDHVASAFQRVLGIPTAVSRLNSSWPEPPRPSQIDKNGRRSTTASDDSGATDAVQPHESFSQYPHRSVFDLFSSMSPMQALFEADKLTESLYQVMWISFLIDSPYSPLRLHDLPQPTPKDLPEGVDPTLFGFEDAFEDLLMVSSGQGLPDINERVRFRKECRESFPRGLPPILWLHQLTRQGLWDGWLTRPEVLDGAVSERWRRWLQEQDDPFHEGRSLPAPNQPSPKEPEMAPVFEKAAREVRARPEQDDHRETEEDSYFSVMGKARLNTSRETSTSTPTSESPKLNSTTRDLSPRGLPAGWRVVEKVQEREDAKGNVHVTKTVTTFNDRGEEVGRQTERRSEYAWTATFSTGNGKSRDQQQRDTNGDGNDKSSWFWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCU2</accession>
    <name>E3QCU2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Tryptophan--tRNA ligase, mitochondrial</fullName>
            <ecNumber evidence="3">6.1.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Tryptophanyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_03824</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.2" evidence="3"/>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092700.1">
        <property type="nucleotide sequence ID" value="XM_008094509.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCU2"/>
    <dbReference type="STRING" id="645133.E3QCU2"/>
    <dbReference type="GeneID" id="24409189"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03824"/>
    <dbReference type="eggNOG" id="KOG2713">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029244_1_3_1"/>
    <dbReference type="OrthoDB" id="15808at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004830">
        <property type="term" value="F:tryptophan-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070183">
        <property type="term" value="P:mitochondrial tryptophanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00806">
        <property type="entry name" value="TrpRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000082">
        <property type="entry name" value="MSW1p Mitochondrial tryptophanyl-tRNA synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.240.10:FF:000002">
        <property type="entry name" value="Tryptophan--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.240.10">
        <property type="entry name" value="Tyrosyl-Transfer RNA Synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002306">
        <property type="entry name" value="Trp-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050203">
        <property type="entry name" value="Trp-tRNA_synthetase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00233">
        <property type="entry name" value="trpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43766">
        <property type="entry name" value="TRYPTOPHAN--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43766:SF1">
        <property type="entry name" value="TRYPTOPHAN--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01039">
        <property type="entry name" value="TRNASYNTHTRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11 12" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00069760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ28680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="368" mass="41002" checksum="92B3209BFD150210" modified="2011-01-11" version="1">MWRHARPVARQLRTLDGRRAASTEKQKVIFSGIQPTGTPHLGNYAGAIRQWVQLQSEPADYCRLIYSVVDLHAITVPQQAKQLSQWKRETLAALLATGINPERSTLFYQSSVPSHSELMWILSCTASMGYLSRMTQWKSKLSLSSDATILDESAKASLKLGLFSYPVLQAADILVHRATHVPVGDDQRQHLEFARECVTNFNHHFGPHLVLPKTITSTARRVMSLQQPNQKMSKSANDPRSRILIIDTPEEIHNKIMSARTDSSNYVSYDPTNRPGVSNLVEILSIFDSQGRTPCQLAETLSQTSLKDLKQIVSAAVVQGLDGIRARYFDFLSADEGKYLDAVEAQGAKRARLSAEETMTIVREATGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCX5</accession>
    <name>E3QCX5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphoribosylglycinamide formyltransferase</fullName>
            <ecNumber evidence="2">2.1.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">5'-phosphoribosylglycinamide transformylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">GAR transformylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_03891</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>N(1)-(5-phospho-beta-D-ribosyl)glycinamide + (6R)-10-formyltetrahydrofolate = N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide + (6S)-5,6,7,8-tetrahydrofolate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15053"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:143788"/>
            <dbReference type="ChEBI" id="CHEBI:147286"/>
            <dbReference type="ChEBI" id="CHEBI:195366"/>
            <dbReference type="EC" id="2.1.2.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via de novo pathway; N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide from N(1)-(5-phospho-D-ribosyl)glycinamide (10-formyl THF route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the GART family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.2" evidence="2"/>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092767.1">
        <property type="nucleotide sequence ID" value="XM_008094576.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCX5"/>
    <dbReference type="STRING" id="645133.E3QCX5"/>
    <dbReference type="GeneID" id="24409256"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03891"/>
    <dbReference type="eggNOG" id="KOG3076">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038395_0_1_1"/>
    <dbReference type="OrthoDB" id="5575075at2759"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00126"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004644">
        <property type="term" value="F:phosphoribosylglycinamide formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046084">
        <property type="term" value="P:adenine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd08645">
        <property type="entry name" value="FMT_core_GART"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.170:FF:000009">
        <property type="entry name" value="Phosphoribosylglycinamide formyltransferase (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.170">
        <property type="entry name" value="Formyl transferase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01930">
        <property type="entry name" value="PurN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004607">
        <property type="entry name" value="GART"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001555">
        <property type="entry name" value="GART_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00639">
        <property type="entry name" value="PurN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43369">
        <property type="entry name" value="PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43369:SF2">
        <property type="entry name" value="PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="Formyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00373">
        <property type="entry name" value="GART"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Formyl transferase N-terminal" evidence="10">
        <location>
            <begin position="8"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00041324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00041682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ28747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="236" mass="25871" checksum="F82DD5EC34B97B46" modified="2011-01-11" version="1">MDASEHCRLVVLCSGSGTNLQAIIDAIAAGTIPDSKIERVVVNRKNAFAVQRAEKAGIPTKYFNQVSGGFTQKGEKDETKLKEGRARYDAALAEVVLQDKPDLVILAGWMAIFTSSFLRPLDAAGVPVINLHPALPGAYDGANAIGRAYDDFKAGKLKNNRTGAMIHYVIEAVDRGEPILVEEVEVREDDSLADLEERMHSIEHQIIVKATAKVVQEILAKKQQHRWQQLAESKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCY6</accession>
    <name>E3QCY6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">V-type proton ATPase subunit H</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_03902</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the V-ATPase H subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092778.1">
        <property type="nucleotide sequence ID" value="XM_008094587.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCY6"/>
    <dbReference type="STRING" id="645133.E3QCY6"/>
    <dbReference type="GeneID" id="24409267"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03902"/>
    <dbReference type="eggNOG" id="KOG2759">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025709_4_0_1"/>
    <dbReference type="OrthoDB" id="10263554at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000221">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000326">
        <property type="entry name" value="V-type proton ATPase subunit H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.150:FF:000002">
        <property type="entry name" value="V-type proton ATPase subunit H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.150">
        <property type="entry name" value="V-type ATPase, subunit H, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004908">
        <property type="entry name" value="ATPase_V1-cplx_hsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011987">
        <property type="entry name" value="ATPase_V1-cplx_hsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038497">
        <property type="entry name" value="ATPase_V1-cplx_hsu_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10698">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10698:SF0">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11698">
        <property type="entry name" value="V-ATPase_H_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03224">
        <property type="entry name" value="V-ATPase_H_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF032184">
        <property type="entry name" value="ATPase_V1_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATPase V1 complex subunit H C-terminal" evidence="6">
        <location>
            <begin position="359"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR032184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF11698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ28758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="479" mass="53065" checksum="671720A88FFB9F6B" modified="2011-01-11" version="1">MSLDTPTYLGSLQDNIRQRPIPWDGAVRAGTITEDHLARIRAVDKAKKPEARKEIVEGDLDGYRSLFVGEPGKPSVLESAGKQAKIVQYILVLLADLLPSVPSLSKAIFKSSDPYKHFLPLLAHSNNTEDPIPLLTSTALTKLMSLAGDESQATKNAIPVLLSYLSGLAKSSDAGLQDIAVQEYSSILYGHASRQQFWNQRSETIAPLIEILRTAAGIGSNGSSSASIWSGTAPTRAPGFEGSLGGGVGLQLLYHVLLVIWQMSFEAEQIGDELNDEYDIVLLYTQLLRLSPKEKTTRLVVSTLFNLLSNNQKSLLPTAVLARLPSLLENLSGRHLTDPDLLEDAQQLKDLLEEYTKTKTTFDEYVAEVESGHLRWSPPHRSQVFWAENARKILEYENGAITRKLAEIMKKPWENDKAVLAIACNDVGALVKEVPEKRYQLEKLGLKTRIMELMGEADENVRWESLKALGGWLKYSFEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDC1</accession>
    <name>E3QDC1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glutathione-dependent formaldehyde-activating</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_04037</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092913.1">
        <property type="nucleotide sequence ID" value="XM_008094722.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDC1"/>
    <dbReference type="STRING" id="645133.E3QDC1"/>
    <dbReference type="GeneID" id="24409402"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04037"/>
    <dbReference type="eggNOG" id="ENOG502SV9S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055491_6_1_1"/>
    <dbReference type="OrthoDB" id="406544at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1590.10">
        <property type="entry name" value="glutathione-dependent formaldehyde- activating enzyme (gfa)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337:SF33">
        <property type="entry name" value="CENP-V_GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337">
        <property type="entry name" value="GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="6">
        <location>
            <begin position="15"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="88"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ28893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="232" mass="25011" checksum="C7DB4BFB955A177F" modified="2011-01-11" version="1">MSHHVNGDPSSIFPLEGGCACGNIRYSLNASPLVVHCCYCTCCQRETGTAFALNAVVEGDEVTLLPSNPSASPIQPLASFPNSIRDDWTHKLSGPDGNHEINKSGGSTGEQSRAGISSPVMLPVPAESGAPQHIARCPLCLTPVWSNYDGTGPLMKFIRVGTLDSSALLGGPDAYIFTRSKQPFLEIANDGKPRFDGFYPSKEGVWSPEALVRRDKLIVRVKKWREENGLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDC8</accession>
    <name>E3QDC8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Arabinogalactan endo-beta-1,4-galactanase</fullName>
            <ecNumber evidence="3 7">3.2.1.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_04044</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>The enzyme specifically hydrolyzes (1-&gt;4)-beta-D-galactosidic linkages in type I arabinogalactans.</text>
            <dbReference type="EC" id="3.2.1.89"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glycosyl hydrolase 53 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.89" evidence="3 7"/>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092920.1">
        <property type="nucleotide sequence ID" value="XM_008094729.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDC8"/>
    <dbReference type="STRING" id="645133.E3QDC8"/>
    <dbReference type="GeneID" id="24409409"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04044"/>
    <dbReference type="eggNOG" id="ENOG502QU6R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011259_0_0_1"/>
    <dbReference type="OrthoDB" id="110914at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031218">
        <property type="term" value="F:arabinogalactan endo-1,4-beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015926">
        <property type="term" value="F:glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030247">
        <property type="term" value="F:polysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016998">
        <property type="term" value="P:cell wall macromolecule catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000077">
        <property type="entry name" value="Arabinogalactan endo-beta-1,4-galactanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011683">
        <property type="entry name" value="Glyco_hydro_53"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34983">
        <property type="entry name" value="ARABINOGALACTAN ENDO-BETA-1,4-GALACTANASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34983:SF1">
        <property type="entry name" value="ARABINOGALACTAN ENDO-BETA-1,4-GALACTANASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07745">
        <property type="entry name" value="Glyco_hydro_53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005127918" description="Arabinogalactan endo-beta-1,4-galactanase" evidence="7">
        <location>
            <begin position="19"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00068680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ28900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="350" mass="38088" checksum="8C21D19C3A7CED61" modified="2011-01-11" version="1">MLVSVASVLLLALSAANAALTYKGADWSSASIEEKAGIKYKSSSGASQSLEVILKNAGVNSVRQRVWVNPSNGDYNLNYNLALAKRAKAQGLSVYLTLHFSDTWADPSKQAIPSGWPSDIDNLSWRLYNYTLEVSNAFQQAGVPPAIISIGNEIRAGLLFNTGRTSNWYNVARLLNSAAYGIKDSSLSPKPKIMIHLDNGWDWNTQNTWYTNVLAQNVLKTSDFDMMGVSYYPFYGSGATLSALKTSLTNMANKWGKEIVVAETNWPTSCPSPAYAFPSDLKDIPFSAAGQTTFVKRVADVVAGVRNGKGLYYWEPAWVDNQALGSSCPSNTLFSWPGTALSSLDVFKSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDN1</accession>
    <name>E3QDN1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">aldehyde dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="3">1.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_04113</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ28969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092989.1">
        <property type="nucleotide sequence ID" value="XM_008094798.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDN1"/>
    <dbReference type="STRING" id="645133.E3QDN1"/>
    <dbReference type="GeneID" id="24409478"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04113"/>
    <dbReference type="eggNOG" id="KOG2450">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_0_1_1"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046394">
        <property type="term" value="P:carboxylic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006598">
        <property type="term" value="P:polyamine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000050">
        <property type="entry name" value="Aldehyde dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000026">
        <property type="entry name" value="Aldehyde dehydrogenase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000012">
        <property type="entry name" value="Betaine aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43720">
        <property type="entry name" value="2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43720:SF3">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE ALDH (AFU_ORTHOLOGUE AFUA_8G02310)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="6">
        <location>
            <begin position="28"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ28969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="499" mass="53876" checksum="47D45534DC4968BA" modified="2011-01-11" version="1">MEDITVELTAPNGQKWTQPTGLFINNEFVPSSTGQTIPAIDPATEEEIASVHAASADDVDKAVKAAAAALKNPAWKSLSASDRGVLMARLADLMESNKELLATIDAWDNGKTYTEALTNDLVEAVGVIRYYSGWCDKIFGQTIALPNKFAYTIRQPIGVVGQIIPWNYPLSMATWKLGPALACGNTVVLKAAEQTPLSILVLGRLVKEAGFPPGVVNFINGLGKDAGAALVQHPLVDKVAFTGSTGTATNIMKMASATLKNVTLETGGKSPLLVFNDADLEQAVKWAHLGIMSNQGQICTATSRILVQKDIYETFIVQFIEEIHKTSKVGNQWDLETYQGPQVSKQQYDRVLAYIQAGRDEGATVKTGGERPAHLGKGYYVSPTVFTDVKSDMRIWREEIFGPVVVIQEFGEEAEAIEIANDSVYGLGAAVFTTNLERAHRVASEIESGMVWINSSQDCDPRVPFGGVKQSGIGRELGEAGLEAYSQIKAVHVNMGNKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDW9</accession>
    <name>E3QDW9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_04201</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093077.1">
        <property type="nucleotide sequence ID" value="XM_008094886.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDW9"/>
    <dbReference type="STRING" id="645133.E3QDW9"/>
    <dbReference type="GeneID" id="24409566"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04201"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_3_1"/>
    <dbReference type="OrthoDB" id="47007at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43639">
        <property type="entry name" value="OXIDOREDUCTASE, SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_5G02870)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43639:SF1">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="4">
        <location>
            <begin position="26"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ29057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="278" mass="29165" checksum="F8351406593BBF20" modified="2011-01-11" version="1">MAPAATDNAAAQQSAGYDAARPFVGKVALITGSGRGIGRGIAIELGRRGANVVVNYASSAKAAEEVVAEIEKLGAKAVAYKADISKPAEVVDLFDRAVAHFGRMDFVISNSGKEVWCPEEEVTEELFQNIFDLNTRGQFFVAQQGLKHCSRGGRVILTSSIAAQMGGIPNHALYAGSKAAVEGFTRAFAVDCGAKGVTVNAIAPGGVKTDMFDENAWHYVPNGYKGMPMEIIDQGLANLNPLKRVGVPADVGKVVASLCHPDCEWINGQVIKVTGGGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEG8</accession>
    <name>E3QEG8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ThiJ/PfpI family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04418</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093294.1">
        <property type="nucleotide sequence ID" value="XM_008095103.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEG8"/>
    <dbReference type="GeneID" id="24409783"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04418"/>
    <dbReference type="eggNOG" id="ENOG502SNXF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_44_8_1"/>
    <dbReference type="OrthoDB" id="543156at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052158">
        <property type="entry name" value="INH-QAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130">
        <property type="entry name" value="ARAC-FAMILY TRANSCRIPTIONAL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130:SF7">
        <property type="entry name" value="DJ-1_PFPI DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1/PfpI" evidence="1">
        <location>
            <begin position="78"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="265" mass="28965" checksum="55B7C59DF707A8CF" modified="2011-01-11" version="1">MPNNKTVKVGVFIPSECQLLDMACVDVLATMSREYLSLLPMLPKHIPALAPSMSFFYITAPATASGETTEQHSLGLLQLTAGAKILATHGISHPDVQPGKLDILLVPGPDPGTHWNEDVLGFLKDHAEQRETTDVLSICTGVFLCGAAGVLEGNMVCGPRGLQDVLRKRFPGAEFVGEKYRWFQDGNFWSCGGITNGNDLVAAYARNSKKHFPPAIAEIGCQMTDVGDRPQLYEQGQTMFLMGFLWQIVKAWFGKPSKGTQRKEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEI5</accession>
    <name>E3QEI5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_04435</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04435"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="101"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="140"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="242"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="344"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="53"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="157"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="257"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ29291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="394" mass="42642" checksum="75CD227FC8EB1B87" modified="2011-01-11" version="1">MSYQYPPPLPYSGSGMGVSHSGYVPSYDATAPIPLPMDPRTQEQTLRDRKESFSQASLKLRRSMSTPDVKQRQTSISDANQSGLASEKRRNKLGYHRTSVACGHCRRRKIRCIASPAMGESRCINCIRLKKECSFFPVDQPPLPQTTGPRPKAPSQASSGPNTASASSSPAVAAMQSLDVTQRQQYRPGVVHPVPGMPPPPKQPSAIENLGTEAAISSGVPGGLPSRAFGYPNQSVAWISPEVSPSSTQPKEHNETWKSFTGQSPITPSFSPYTSQAPSSAGWSNADPNAPGDMGYYSFAPGSTMTYPRNTPLPTQYSMAPQQSQQFGRKSSTMSDVYPAQIATHLPDFDPNNASLSAGAAPSSDYASWEQPPYTYARPHEGYQAWTYEENEGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QES2</accession>
    <name>E3QES2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04522</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008095207.1"/>
    </dbReference>
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    <dbReference type="STRING" id="645133.E3QES2"/>
    <dbReference type="GeneID" id="24409887"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04522"/>
    <dbReference type="eggNOG" id="ENOG502T401">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_350542_0_0_1"/>
    <dbReference type="OrthoDB" id="4845923at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="671"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="43"/>
        </location>
    </feature>
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        <location>
            <begin position="73"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="111"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="156"/>
        </location>
    </feature>
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        <location>
            <begin position="226"/>
            <end position="236"/>
        </location>
    </feature>
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        <location>
            <begin position="349"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="403"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="700"/>
            <end position="710"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="867" mass="94229" checksum="AAEC80F972FD5B16" modified="2011-01-11" version="1">MTTTVCYPANGGNQRTSPPGLAPYDETSSSSSSSSLSLPSSPASEHHQRSPTGLFGVQTHGVEETEALAKGATGRKRTRASGRGRFPLLGGGGRGKRRRLRSSSGGGGGESSIIKTTDITTTTSGRAKVRPLKNDMTGRERPKTSRRNPAETEKVPRLPHLCFPEFGLMMKEAGISATIEGSASTSVHEEDIGVEASSNESVLSKDRSPGCLLGLRDNDDTGSQEGPKKPTKDGLGIHRPASVDFEGRRMDEEEEAPHGVSYDIPRPTTGLGWYEDDASSVKSTVDHFDSQSSVRDSDGSAESIALDSQPLAVHQDPLRCSPFIRCCSQASSLPEVGGTPTTESKHNKLSPSMSTVMKNTSSFLRFSTDDDDDDDDDWLGPRPVESGSVSHQHIEYSPAHAEPSSNSIMEDSNTVSPISHKPFSISEEEQEIDDIIDIYATSPDRTPVQYSGDLPPYPPYHHYASDPLRTIARGLSLPPTTSFADLQEYLARNANILRYLVLHCIPSPSINPIEYVTDLVEPILPLPLPPHPSIAQNYPPHPRRREYTGLLQAVRSVQWSADVINDMLAVVDSDPSPPGSRGRRSTALPMFRKLRAADAQRKGHLTSAQLHRLHRHGVSLLDVLQMNDVPKVVARGLSERLMEAAESGVLEIAKEGNLLDEEGALLELLVDPGDTVPTSPRGERRGRRREGSGLRNCVGADEDDGETTDDENEYYEAGTAVESLFEHADDGRNVDDMWYTVSPLSPDANPDEHGWNHDDVSPLTTSCRLQELEALFHEVRVLSSEKTRPADGTTPEPPRKAIRRTRVLRTCGDRGGVLVDEETAKSPEMQRFFHVIGAPPPPADPDSRLAKGGRRSWGVDLGGILSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QF99</accession>
    <name>E3QF99_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein Asterix</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_04681</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093557.1">
        <property type="nucleotide sequence ID" value="XM_008095366.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QF99"/>
    <dbReference type="STRING" id="645133.E3QF99"/>
    <dbReference type="GeneID" id="24410046"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04681"/>
    <dbReference type="eggNOG" id="ENOG502S6JB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129456_0_0_1"/>
    <dbReference type="OrthoDB" id="284718at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045048">
        <property type="term" value="P:protein insertion into ER membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005351">
        <property type="entry name" value="ASTER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28038">
        <property type="entry name" value="ADL329WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28038:SF1">
        <property type="entry name" value="ADL329WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03669">
        <property type="entry name" value="ASTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ29537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="116" mass="12405" checksum="AE215854EBF7606B" modified="2011-01-11" version="1">MASKRDMRRPDLIVPYQEPRAKGDTTDMSSTLSSTLPMAAMLTRNKFIGWASVVFSIQTWLGESEETKKSSATPGYFSVGMSIMALAVTYLPLFLPPPVQRGAATGTGPAAPVPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QG86</accession>
    <name>E3QG86_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CRAL/TRIO N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_04826</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093702.1">
        <property type="nucleotide sequence ID" value="XM_008095511.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QG86"/>
    <dbReference type="STRING" id="645133.E3QG86"/>
    <dbReference type="GeneID" id="24410191"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04826"/>
    <dbReference type="eggNOG" id="KOG1470">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1506908_0_0_1"/>
    <dbReference type="OrthoDB" id="75724at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008526">
        <property type="term" value="F:phosphatidylinositol transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052578">
        <property type="entry name" value="PI_Transfer_CRAL-TRIO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45824">
        <property type="entry name" value="GH16843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45824:SF29">
        <property type="entry name" value="GH16843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03765">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL/TRIO N-terminal" evidence="2">
        <location>
            <begin position="90"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ29682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="179" mass="19715" checksum="F8286C7197FD0863" modified="2011-01-11" version="1" fragment="single">MASVADQTPASTGPQEKAAPATSSGPLKTPIASPAAATSIPAVPPLSPDQQSKYDGLLSHARAWTEVKCAAPAHADKSGPLTDSDRQWLTRECLLRYLRATKWVPKDAEKRLLETLAWRREYGVEGLTPDHISPENETGKQIILGFDKERRPCHYLSPGRQNTDPSPRQVQHLVFMVER</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3QH52</accession>
    <name>E3QH52_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="7">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_05358</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="7">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="7"/>
    <dbReference type="EMBL" id="GG697348">
        <property type="protein sequence ID" value="EFQ30214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094234.1">
        <property type="nucleotide sequence ID" value="XM_008096043.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QH52"/>
    <dbReference type="STRING" id="645133.E3QH52"/>
    <dbReference type="GeneID" id="24410723"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05358"/>
    <dbReference type="eggNOG" id="KOG0342">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_26_6_1"/>
    <dbReference type="OrthoDB" id="193716at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17964">
        <property type="entry name" value="DEADc_MSS116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="94"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="310"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="535"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="547"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ30214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="577" mass="62107" checksum="8188D5C49443F50D" modified="2011-01-11" version="1">MDRRGRGSNQKRGGPRSGRRDAPYNDSPRSAAQSAPAPAAPAPQSTAPPLTEPVPEDTPRFADMVGVNPALIQAITQDLKFDHMMPVQAATLTELLPPKRGDCLVQAKTGTGKTIAFLLPAIQTLITNNRGRGAGISLLVISPTRELAMQIAKEAQALLQRLQQYRVCIAIGGTNKDREEKQILNGCDILIATPGRLIDHLSNEYIKESFRHLDTLVLDEADRLLDMGFMPALKDIVRALPDKAQTNRQGMLFSATIAPHVEQVAGLVLSKGYKFISTIPAGEANTHERVPQHLIKVPTFAAVAPAMVGAIREEAAHVGPETFKAIIFAPTAALADFYGDVLANVPGMPPTAVLHSRISQSKRTKTTNDYRDSKSGIIVATDVIARGMDFPGVTSVFQVGIPADKESYIHRLGRTARAGAEGRGIFIVAEIEGFFPQWTLKEISFETRRADLSSAEQVYEIAEQRIDEAQKAKIYQAWLGYYKNWMKSLKWDKEQLVAEGNIFARDALAAPETPAIQKSTIGKMGLRGTRGLVVIPDAPKGRHGHRGGGGGGGEGRSAGSGGRGGGGGGRGRRGGRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHU2</accession>
    <name>E3QHU2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fungal specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_05574</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697349">
        <property type="protein sequence ID" value="EFQ30430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094450.1">
        <property type="nucleotide sequence ID" value="XM_008096259.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHU2"/>
    <dbReference type="STRING" id="645133.E3QHU2"/>
    <dbReference type="GeneID" id="24410939"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05574"/>
    <dbReference type="eggNOG" id="ENOG502S1X9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015361_2_0_1"/>
    <dbReference type="OrthoDB" id="10031947at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052073">
        <property type="entry name" value="Amide_Lactam_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47171">
        <property type="entry name" value="FARA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47171:SF6">
        <property type="entry name" value="SPECIFIC TRANSCRIPTION FACTOR, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G06130)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ30430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="664" mass="71386" checksum="00BA813F25B284A0" modified="2011-01-11" version="1">MNNPAKGVKFVGSDASGLPLKRKQVQQACDSCRRKKKRCIHAEPSSAEPAQANGHDGPAGSSPARDVHTASGIASPVKHRNSTTAAPDALSMSPSRRDSSAAGQADHAQTPQTRFVGDLNPEGMFAEAADPEAAANPTQKAEVGVWLPSVNTTAAQSTASVVSRPLAMVDRALLPFVRENCLKCVPPEKDFKHLHRVYRDKIHPIFALIPEDVVDDGDSPTAVVMRQVVSLAAAADPDMKSHLRLANQGNKKLSYQDFSQTISGSVRTILETSLITDRTVHIRALCMLSLYVQPSSADEADLPAQLGAKAAHHSQTLGLHLFHSSDDALDTLFCAVWALDRINAAAYGRPCVLHEGDIGPGLDDCFRRQQPCFRLFLSVVQWLDKVIELYRPGVIAQSLESKPYIDLPVLEPMILEAEALQVSTPLLATIEVFYHAVIILSCRLSRPGPPAQYASSIPPASANARRSLAAERISSAIRRDHLSPVPLVPYALSLALSVEYRKMRHSALPMFRARARSAFKSNSELMKRFGDVYWSARVVAGLGERILREMERAANSIAQGAAGAPLPSSVTDIPTNGRAEAPAAVAAVPDAAPAASTAAATTTSTTEFPPLDAIDFSIVDAMPHLDVFGHFDPSFNLPAIDNALEANLDIGLPLNWGEWDHFAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHY2</accession>
    <name>E3QHY2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mitochondrial carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_05614</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697349">
        <property type="protein sequence ID" value="EFQ30470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094490.1">
        <property type="nucleotide sequence ID" value="XM_008096299.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHY2"/>
    <dbReference type="GeneID" id="24410979"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05614"/>
    <dbReference type="eggNOG" id="ENOG502T4CS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2265766_0_0_1"/>
    <dbReference type="OrthoDB" id="4801050at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ30470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="110" mass="12046" checksum="A857043D1637847D" modified="2011-01-11" version="1">MSSSSSSSSSSSLSSGTPLLRPPSARTLWIADNWTSILGGTVFVHFAHYQYLTRIRTPNPNPLKNARFWALAGGGWMLSYLSIITGIAIAQAKANHYRDPDTRSLYTDDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIJ2</accession>
    <name>E3QIJ2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05746</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094622.1">
        <property type="nucleotide sequence ID" value="XM_008096431.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIJ2"/>
    <dbReference type="GeneID" id="24411111"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05746"/>
    <dbReference type="eggNOG" id="ENOG502RP62">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1085911_0_0_1"/>
    <dbReference type="OrthoDB" id="4851276at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="239" mass="25472" checksum="8DEE33FD9E80B1D1" modified="2011-01-11" version="1">MSNPKDNNLPVQPDELQEHNSLQPLTYIDVASEHSTSVTTPAGDGAPPESSAFVKDDALRTQEPETANDCNYGNIPSEMSSSLARGRAWYSDAQSQSSPEATGNQSGFTRSQTADNHRKSKTEFNSIPDEVVPVGLDMARSPGTGSQAHRKSSTEFGKIVAPGKSSPLHALTLSSTLILSPDAGLAKQPHVQDQAAALPPVVPKPHSAPGEKQDNGGRKADSQLWQKPEAQGSSQQLWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIT2</accession>
    <name>E3QIT2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="13">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_05914</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094790.1">
        <property type="nucleotide sequence ID" value="XM_008096599.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QIT2"/>
    <dbReference type="GeneID" id="24411279"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05914"/>
    <dbReference type="eggNOG" id="KOG0055">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_17_2_1"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18577">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03249">
        <property type="entry name" value="ABC_MTABC3_MDL1_MDL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000913">
        <property type="entry name" value="ABC multidrug transporter SitT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF11">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="51"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="284"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="311"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="732"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="776"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="855"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="881"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="962"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="55"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="379"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="736"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1060"/>
            <end position="1300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ30770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1305" mass="142666" checksum="20682A96C22C6D18" modified="2011-01-11" version="1">MAESPLRTDVTSTPDKGTMATAMTTTTTTPVRKPKFTDYLRVFTYATKWDFCVYVIASVASVAAGVTLPLMNIIFGQLVSQFTSYFSDDATVSRAQFDSILNRQALYIMALFVGRWALNAVNKFCFRMIGIRLSSAIRLHYLQSLFAQPIHVIDSMPPGAAATAITGTSAVLQIGISDRLGTFLQFNGTIWAALVIAFIWSWDLTLVTSSLILYILIVLGVVMPIIVKGETATTEADAQGTAIASEALGGIRLVMACGAQSHIISRYEGWVQEAMRRAQRTAPVVAIQFGLIFFGVFGAFGLAFWYGTQRYIAGALDNAGVVVVVLMSVMMILTSLERISTPIIAVSKAMVAACELFTVIDAPLPPAGTLKPEIDSEDIVFEDVTFEYPSRAGVKVLNSLNFRIQPGQNIALVGPSGSGKSTIVGLLERWYSLREQHALPRVADDQASEKPHDETVECVNEELKSLIMPNLSGTISVGGVNIEDLDLKWWRAQVGLVQQEPFLFNNTIFNNVANGLIGTDWENEPETVKRELVRDACQESYAHEFISRLPDGYDTRVGDGGAKLSGGQKQRLAIARSIIKKPRIIILDEATSAIDAKSEKIVQAALDRVTHGRTTITIAHRLSTIKKADNIVVLQRGQAVEQGTHHSLLSDPSSVYSSLVRAQALHLSTPEKSVSEASASGLDSEMEEKVFTDQDHRPTAAFMDTLEHNVPHKSRGLVRSFGKLLYEHKANWTSYVAVILSCMATAAGTPIQAWLFSKVLSVFLLTGDDLKRRSDFWGLMWFALAGGVGLAYVAQCWIGLRLQYFVSAAYKKQYLNDMLHQHLSFFDDDKNSHGALSARISGDAKLLEELLGLNLAMLLSGVFTVIGCVAIALIFGWKLGLVAMFITMPIMLGAGLWKYRHEVQFDQMNMAVFGESSQFATEAIGAIRTVSSLGMESTINARYEKLLSGHILAARRKAQWTAVLYGFADSVSLGCQALVFWYGGRLLASGEYSMEAFFVCFMAIIQGAEAASQILAVAPSAAQAAAAADRILDVRESADVGQAAIRGCEEIVGAEGGVRVELRDVHFKYPTRDVIVFEGLNLAIEQGQYAAFVGPSGCGKTTIISLLERFYELGKGHGSILCNGVNIHDLDVYDYRQNISLVAQEPVMFRGTVRDNILFGIEDPSSISDERIHEVCIEAFIHDFIVSLPEGYDTDVGAKGVSMSGGQKQRIAIARALIREPKLLLLDEATSALDSESEKIVQAAFERARDGRTVVAVAHRLSTIQNADVIFVFSEGRVVEKGSHHELIRKQGVYWEMCQSQALDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIT4</accession>
    <name>E3QIT4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">catechol O-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_05916</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.6" evidence="1"/>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094792.1">
        <property type="nucleotide sequence ID" value="XM_008096601.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIT4"/>
    <dbReference type="STRING" id="645133.E3QIT4"/>
    <dbReference type="GeneID" id="24411281"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05916"/>
    <dbReference type="eggNOG" id="KOG1663">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050461_0_0_1"/>
    <dbReference type="OrthoDB" id="186626at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006584">
        <property type="term" value="P:catecholamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002935">
        <property type="entry name" value="SAM_O-MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43836">
        <property type="entry name" value="CATECHOL O-METHYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43836:SF2">
        <property type="entry name" value="CATECHOL O-METHYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01596">
        <property type="entry name" value="Methyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51682">
        <property type="entry name" value="SAM_OMT_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0128">Catecholamine metabolism</keyword>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="223"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="231"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ30772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="289" mass="31456" checksum="D2C1EC0BB6A60D24" modified="2011-01-11" version="1">MPHFDESKAYAAQEDVFFDDGREIELLHFVYSQPDLDEIRGSPERVLKAIDDFGRTKKYLMNVGEDKGKIVTDLIAEVKPKIMVELGGYVGYSCILFGAAARAAVADAKYYSLERNPEFAAVIGSLVDLAGLSATVKVVVGPSDASIARLHAAGSLPKVDLMFLDHYKPAYTTDLKLCEQIGVVGPGSVLAADNVIKPGNPPYLEYVRSSVAQKRAAAARDAGKTKGLSGWHDDRAAKQYEKREGEERLDLSRIGNPNLEYESRLVNSFEPTGVPDGVEVTKCVGEAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIW4</accession>
    <name>E3QIW4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_05946</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. TCR/Tet family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094822.1">
        <property type="nucleotide sequence ID" value="XM_008096631.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIW4"/>
    <dbReference type="GeneID" id="24411311"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05946"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_14_0_1"/>
    <dbReference type="OrthoDB" id="10021397at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000489">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000196">
        <property type="entry name" value="MFS toxin efflux pump (AflT)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF49">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="344"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="384"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="411"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="437"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="469"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="500"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="541"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="572"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="609"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="649"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="677"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="808"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="347"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="98"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="149"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="30"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="111"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ30802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="841" mass="90745" checksum="62DA414780B8EAD8" modified="2011-01-11" version="1">MADDNHPEKPEGGGNNTTPREEDVPQWPSIDERPSSEFLGEEKWRVSIFNPDSDDSTVALPDLGDKGSLPSYCEDEDDDEEAILPAWLTEAWQEKAQLSKECTSAPAAEADESKETQVDEPVADDKPHRGSRISSAGFRCSQCGHYRRDSMRSSTTFGNGPQLPTEHQHESCLRRPASLSLFPRTRPPSPLSTQRAFPLSVKRVPSKAVSDAQTFYSAQEGEGVNSPEPHSETASVISSIFATPLRHLASNPSLRGSLSTDTATSEEQRVTPIAEQRHPGKAGARISRFTRPFEPDIDEEDDGSGYRRQVMDMEVVRAEKQGSELTQTADGKDEKEEWVEGWRLAFLLLGICLVVFLISVDRTILTTAIPYITSEFQSTADIGWYGSAYLLTACAFQPVFGRVFMLFSIKWSYMLAMFMFLVGSLICGLAPNSVALIVGRAVAGFGSAGILTGSFVVVAMAVPLRLRPIYTAIVGLMFGLGATVSPLLGGVFTDLVTWRWCFYINLPVGGVTVLVFLLFLHPQRRPRHEQTFFDRFMDLDIVGNVLLLGACVMLFLVLEFTAQGEAWSSPRVAGLLASAGATAAVFAAWQWWKQDGALIPPAIVTQRTVAASCVAAFATYGALLIHSYFLPLWFQAVKGESATSSGVDMIPYVATNALFSLFSGFFVSVVGYFVPPAVVGGVIATAGCGVFLLLSQDSPTTQWIGFEILVSAGFGMSIQQGFTAVQAILPPDDISIGTAAVVASQSLGGAIFISVGNTLFQNHLLQASAQNMVPGVDIRAVLEGGATAFRDVVPASALPMMLTVYNEALRVAFTAAIPLAGVSVIAACFMEWKSVKGKKAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJ06</accession>
    <name>E3QJ06_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_05988</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the carotenoid oxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094864.1">
        <property type="nucleotide sequence ID" value="XM_008096673.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJ06"/>
    <dbReference type="STRING" id="645133.E3QJ06"/>
    <dbReference type="GeneID" id="24411353"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05988"/>
    <dbReference type="eggNOG" id="KOG1285">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1731329_0_0_1"/>
    <dbReference type="OrthoDB" id="1069523at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004294">
        <property type="entry name" value="Carotenoid_Oase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03055">
        <property type="entry name" value="RPE65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="90"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="110"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ30844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="151" mass="16888" checksum="ECCF5813CCADEA98" modified="2011-01-11" version="1">MKPCRFEGEVRNLEMVGSLPAELDGTFYRVMPDPQFPPFIEDDPWSCVSNAFPGHTTNAYETPEGLIVFDLPLIDKNAFFWWPDAAGSTPGPHDIDPHTASLDPPARHDPRPRRRVPPHRLPRPRPPPCRASCTSSTRGALRSPPPSSRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJ83</accession>
    <name>E3QJ83_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_06065</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ30921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094941.1">
        <property type="nucleotide sequence ID" value="XM_008096750.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJ83"/>
    <dbReference type="GeneID" id="24411430"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06065"/>
    <dbReference type="HOGENOM" id="CLU_2542442_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="83" mass="9064" checksum="ADE9BB450E23B8AB" modified="2011-01-11" version="1">MAKGTTMLQRQVLATKGSGSSGEATSSVSGQGETIRRPGLTVQKLELDRNGKSPSILGLMWKNGLEEKAVGRFPRHKVDRRVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJC1</accession>
    <name>E3QJC1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Acid phosphatase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_06103</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ30959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094979.1">
        <property type="nucleotide sequence ID" value="XM_008096788.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJC1"/>
    <dbReference type="STRING" id="645133.E3QJC1"/>
    <dbReference type="GeneID" id="24411468"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06103"/>
    <dbReference type="eggNOG" id="ENOG502SGJ9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073635_0_0_1"/>
    <dbReference type="OrthoDB" id="5414285at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ30959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="235" mass="25091" checksum="4B80EAA285883DEA" modified="2011-01-11" version="1">MVSVAGGIIITILVLALIGIVGWIIFTQLRARRLGLPPPSLSSYLPFRKSETSPSYGPPRPAPSGISGWFNDKISSFKNRGSRSAAGAYEQPSGAGAPRRGFGPLDPDEAWDARVGHEAETYGPYGNYEEQELGYRGGNGADGGNSYGMNLAATPGVHHDEPARGRSLSRLGDDDARLGGPKAGSRNPFEDDAEPSNISLRGVSPRPIVDTASQQQQKDNGESPTERRSIFRENV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJG1</accession>
    <name>E3QJG1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">H+ symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_06143</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ30999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095019.1">
        <property type="nucleotide sequence ID" value="XM_008096828.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJG1"/>
    <dbReference type="STRING" id="645133.E3QJG1"/>
    <dbReference type="GeneID" id="24411508"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06143"/>
    <dbReference type="eggNOG" id="KOG0252">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_46_14_1"/>
    <dbReference type="OrthoDB" id="433512at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17364">
        <property type="entry name" value="MFS_PhT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004738">
        <property type="entry name" value="Phos_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00887">
        <property type="entry name" value="2A0109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="117"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="211"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="262"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="363"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="399"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="432"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="456"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="536"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="65"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="633"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="713"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="633"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="721"/>
            <end position="733"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ30999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="733" mass="80730" checksum="53AF5AAC27E20FC8" modified="2011-01-11" version="1">MDSALPSPMALPPATDRIYRRTNGGNKAFHNFANDYSHISDPNLRRRLALSEIDKVPFGLYHVRAILVGGVGFFLDSYDIFAINLVTTLLGVVFWQGPPGQHVHGYGGNNGELPSSVNSALKASTSAGIIIGQIVFGWLADVFGRRRMYGVELTIIILATMSAALVSPSQSISFTGLMIFWRVIMGVGIGGDYPLSSVITSEYAPTRWRGAMIAAVFSMQGMGQLGAAVVALVVAEVFKGSYMDVHTLSDCHDRCQLAADRSWRIIVGMGAVPACIALYYRITIPETPRYTFDVEQDVEKADADIRAYMASKSKGEYDPELQAKMKKEAGPAFNTPTASWPDAWAYFSQWVHLKMLIGTSFSWFFLDLAFYGLGLNSTVVLQTIGYADGDNFYERLHNQAVGLIILACAGAIPGYWTSVFTIDTFGRKPIQIMGFFTLSVIFCVLGFMFHQLPDPIFITIYVIGQFFFNFGPNTTTFIVPGECFPTRYRSSGHGISAAMGKVGAILAQVISIPLLARDDVSGDCHGRHCAARLDRLLELFALFMFLGTLSSLLIPETKGMTLEELAGEPPTSYNRGSNGSISNYPRQTSKWNPFSGGQPAGFHYPRIRNIRASRVGIMTSPVFIAEEQRQRRSQSRFWHKKKERGLDSSASGTEDYTRSFRDSVISSAYGRNTGTADEHMPPHSMNPEVIPTWGAGWGRVDRGAQPMDNVKLHDVGSLLQRDSHKDSSRNSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJJ9</accession>
    <name>E3QJJ9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA-directed RNA polymerase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_06181</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ31037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095057.1">
        <property type="nucleotide sequence ID" value="XM_008096866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJJ9"/>
    <dbReference type="STRING" id="645133.E3QJJ9"/>
    <dbReference type="GeneID" id="24411546"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06181"/>
    <dbReference type="eggNOG" id="KOG2907">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093932_1_1_1"/>
    <dbReference type="OrthoDB" id="10056816at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006363">
        <property type="term" value="P:termination of RNA polymerase I transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10507">
        <property type="entry name" value="Zn-ribbon_RPA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019761">
        <property type="entry name" value="DNA-dir_RNA_pol-M_15_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012164">
        <property type="entry name" value="Rpa12/Rpb9/Rpc10/TFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034004">
        <property type="entry name" value="Zn_ribbon_RPA12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001222">
        <property type="entry name" value="Znf_TFIIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239:SF14">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01096">
        <property type="entry name" value="Zn_ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005586">
        <property type="entry name" value="RNApol_RpoM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00440">
        <property type="entry name" value="ZnF_C2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01030">
        <property type="entry name" value="RNA_POL_M_15KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51133">
        <property type="entry name" value="ZF_TFIIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 10 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIS-type" evidence="12">
        <location>
            <begin position="80"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="10">
        <location>
            <begin position="10"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR005586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR005586-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR005586-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ31037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="122" mass="13323" checksum="E47154AB56CC5B35" modified="2011-01-11" version="1">MSAIGTLVFCHDCGNLLPASMGTEKNTLTCDCCGADNKDTGSKTIVTQTKPSDFPSQLRQKLQSNVQAVDRANVSTEATIKETCPKCEREEVRFTAVQLRSADEGSTIFFTCDCGFKWSQNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJY9</accession>
    <name>E3QJY9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-tRNA hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_06321</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697353">
        <property type="protein sequence ID" value="EFQ31177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095197.1">
        <property type="nucleotide sequence ID" value="XM_008097006.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJY9"/>
    <dbReference type="STRING" id="645133.E3QJY9"/>
    <dbReference type="GeneID" id="24411686"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06321"/>
    <dbReference type="eggNOG" id="ENOG502SF32">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070640_0_0_1"/>
    <dbReference type="OrthoDB" id="1733656at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180535" description="Peptidyl-tRNA hydrolase" evidence="2">
        <location>
            <begin position="18"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ31177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="267" mass="29031" checksum="E11CC42341C4A51B" modified="2011-01-11" version="1">MRVSATTILALPLLATAAESPFEQYKAQFQNFLSSFGASAPSADTPAAAAPNGAAPAATPAKKISVLTIENWKDVLHEPVKAEATTPEEWWVLITGGNKTCFGHCDKIETAFNESATKFAKLPESPHLGLLNCDDQPVLCNGISAGTASIWSIGMLPAGSEIDIYRKRLNVTTTTSDDIIDLWKNKSKEDWILTENIFHPFNSFVGKNNLTLPVGYLFWAFNLIPNWLFMLLVSFGSRTIMNRRMNNTIDRRQNAAAGAAPAGSAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKT1</accession>
    <name>E3QKT1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_06613</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697355">
        <property type="protein sequence ID" value="EFQ31469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095489.1">
        <property type="nucleotide sequence ID" value="XM_008097298.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKT1"/>
    <dbReference type="STRING" id="645133.E3QKT1"/>
    <dbReference type="GeneID" id="24411978"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06613"/>
    <dbReference type="eggNOG" id="ENOG502S7RA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030355_0_0_1"/>
    <dbReference type="OrthoDB" id="5394557at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF3">
        <property type="entry name" value="HALOTOLERANCE PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="59"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="305"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="340"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="413"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="305"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="365"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="422"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ31469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="498" mass="51853" checksum="E8C5388286607EF7" modified="2011-01-11" version="1">MVSPSYYSDGRRYSRLDPTYSYPERQQRRSHSSEARTSSTMTERESETDTPPRKRIAVACGRCRKRKIRCSGDTGNGHPCQNCKAAGAESCMFLRVASTEAPWVQNPEFAYELKAARAYQAQQAMVSPLTASPPHYASEMHDSLSRYPPASAGYSSYGSAGGKYYSSAATMPSWSSHPGYSDDGTGAVDYSAAAMGYSYPYQSHDPGYYYRMSAKAAATSAADLYVNADAAAGYGYGGAGAASLVHRPAATPSVQQNEASNFSLSTVAASLPHAAGGGGDRLLPNPAPRLSNTNVLAYRTDSAAAASSSTKSSGSPVPQTSPMSAASEVTAGYTASSVAGPGSYDSSPVTAYPPPAHTLPSMAPQKHHQHHQHHRATNVAEMMGYPPPSTAGGGADSIFSVSDASLRTHGSASDLSYKYTDGSSGASSSTGRRGSGETASSGGSLSNGQQYTVTTPSVGMYAAVAGHGRHHVSQYMISEDAAAEHHASRRSAGGLSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QL32</accession>
    <name>E3QL32_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Retinol dehydrogenase 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_06859</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697356">
        <property type="protein sequence ID" value="EFQ31570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095590.1">
        <property type="nucleotide sequence ID" value="XM_008097399.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QL32"/>
    <dbReference type="STRING" id="645133.E3QL32"/>
    <dbReference type="GeneID" id="24412224"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06859"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_44_4_1"/>
    <dbReference type="OrthoDB" id="542013at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF252">
        <property type="entry name" value="DEHYDROGENASE_REDUCTASE FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G08550)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ31570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="339" mass="37424" checksum="6D1AF716429A10F4" modified="2011-01-11" version="1">MSNDLASQAVWEANPLSFLYRQAVVTPAEIPDQFDLSDCTLIMTGASSGLGLEASRQFLERSLGHLVMGVRNTAKGEALAEGLRREFPMAQIQVWHLEMESYESVRDFAARCKKELSRIDIAILNAAVVAQSYIRAREGHELMLQVNYLSTVLLALLLLPAMREKRPKDEPARLVLVSSDLSYWHTPEEDMVTGSMFKPADNQRLWESDKNYEQSKFLGQLFVAKLATILDPNEVIVNLSSSGLTGGTNIVKPASESFFTGLIKKTLGRSVEVGARSYLDAAIVKGKESHGSFTSDGVIKPWPSVMYTSEGTGLKDRIWAETRKEPGFAEAFAAVEKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLN1</accession>
    <name>E3QLN1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_06744</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697357">
        <property type="protein sequence ID" value="EFQ31769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095789.1">
        <property type="nucleotide sequence ID" value="XM_008097598.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLN1"/>
    <dbReference type="GeneID" id="24412109"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06744"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_2_1"/>
    <dbReference type="OrthoDB" id="2985014at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF32">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="355"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="44"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="22"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ31769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="417" mass="46174" checksum="DC4706F03EC89EEA" modified="2011-01-11" version="1">MDSRADDKMVCDTPTDRSVVASEDKPEWDTEQEQKAKRKVDLTVLPLLVLGLLMFQLDRMNLASALTAGFAKDIDVSQDTINLGNQLMFMGTVVLEIPCNLLLQWFGPRKWISLQVLLFGLVGTLQVLVKNRAGFLAVRLMLGLTEAGYIPGSIYTLSTWYTKRELAKRIAVFMFGQFGGNALSPLVASGILKLAGKGGLAGWQWLFLNAVEGLVTLVVALMLIFLLPGSPDMPKPLASAGIVRFTADQQEILQKRMEVDESGSRRGARGIEIPWALVWKTVKHYKRWPHYVSTFCVFSTWSPLTTYTPSIIMALGFDRTSANALAAVGASLAMAVVFAFATLSDRTNKRGATVILGHICYLTILVVTRSLHPHVGKWSRWGLWTMINAFAVCYHPAHNTWLQVNCRDPGERSIEIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLX1</accession>
    <name>E3QLX1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07003</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095879.1">
        <property type="nucleotide sequence ID" value="XM_008097688.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLX1"/>
    <dbReference type="STRING" id="645133.E3QLX1"/>
    <dbReference type="GeneID" id="24412368"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07003"/>
    <dbReference type="eggNOG" id="KOG0747">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055718_0_0_1"/>
    <dbReference type="OrthoDB" id="16464at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048269">
        <property type="term" value="C:methionine adenosyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048270">
        <property type="term" value="F:methionine adenosyltransferase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006556">
        <property type="term" value="P:S-adenosylmethionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05254">
        <property type="entry name" value="dTDP_HR_like_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005913">
        <property type="entry name" value="dTDP_dehydrorham_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029903">
        <property type="entry name" value="RmlD-like-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10491">
        <property type="entry name" value="DTDP-4-DEHYDRORHAMNOSE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10491:SF4">
        <property type="entry name" value="METHIONINE ADENOSYLTRANSFERASE 2 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04321">
        <property type="entry name" value="RmlD_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RmlD-like substrate binding" evidence="1">
        <location>
            <begin position="10"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="297" mass="33620" checksum="49AAAA88469E16B1" modified="2011-01-11" version="1">MATNGHSGNRFLIWGGKGWVANHLKEILEGQGKEVYTTTVRMEDREAVIAELDKVKPTHVLNCAGCTGRPNVDWCEDNKEATMRSNVIGTLNLTDACYLKDIHCTVFATGCIYQYDDAHPIGGPGYLETDPANFMGSFYSETKGHVEEVMKYYTNCLILRLRMPVSDDLHPRNFVTKIAKYDRVVDIPNSNTILHDLLPASILMAEHKDTGIYNFTNPGAISHNEVLSLFKEIVRPDFTWKNFSLEEQSKVIKAGRSNCKLDTTKLEKKLKEYNYTVPEIHEAYRACFERMKANGAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMF6</accession>
    <name>E3QMF6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07188</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096064.1">
        <property type="nucleotide sequence ID" value="XM_008097873.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMF6"/>
    <dbReference type="GeneID" id="24412553"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07188"/>
    <dbReference type="HOGENOM" id="CLU_874386_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="318" mass="34606" checksum="554A4DDD1176FB54" modified="2011-01-11" version="1">MSSFTQTVNLEAALRHVCSQRATYSNVDLGERSLQVEMMRGIFGSANLLLAWLDTWNQSLAPGALETIANPNGNRAPKYGYVAADPGVPRTRWVGALGGSTPVQHEPRCRGSKGTTCIASWGFDISTSCPTDYTEATSLGDAHRDFVACWLQDPVPTTRAAKPWTFLCYAGSGLGSHMPTMPSWAPNSHVANLLPDMIAYAMELVYAQEPTMSVPRRAGSPMVRRRETGGFPAEAIYSRGVAVIVADLMDGEARGSVWNREGDPRDAGARLRSRSGLRRTPERNPIRSGVVRQRVSAKPTRQRAQAAAPSLDRDDFTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMQ2</accession>
    <name>E3QMQ2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_07284</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096160.1">
        <property type="nucleotide sequence ID" value="XM_008097969.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMQ2"/>
    <dbReference type="STRING" id="645133.E3QMQ2"/>
    <dbReference type="GeneID" id="24412649"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07284"/>
    <dbReference type="eggNOG" id="ENOG502QTC3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026014_1_0_1"/>
    <dbReference type="OrthoDB" id="2153847at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053216">
        <property type="entry name" value="Appressorial_penetr-assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34587:SF1">
        <property type="entry name" value="CIRCUMSPOROZOITE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34587">
        <property type="entry name" value="VWFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180586" evidence="2">
        <location>
            <begin position="20"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="219"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="263"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ32140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="469" mass="48056" checksum="B37F242D670B1E6A" modified="2011-01-11" version="1">MKFQASTAAFAALLTLAAAEVPQEHSHEKYLRAVNDLLKQNNPQNIQDAVFGLLGNAAAADGAGDVKNLDCLHQATADSAFSTAKAAGDVDGMASALVYAAVERNTGKVGLKSVLCTDKAENPEIAALSQHQDPASEGAAETNKAITLELAKQLASVGADPQLALDSGTFKPGDVNDSTGAGNTCDDANDAEGCIFSQNLLVKDASADEIAAAAAEVSGNAGNGADNAANSTKVARRFRSRGRRATTILPSGRRQVREIENRNQNQNQNQNNNAGAATGTNVQTFTGALGGPAPPVNSSPAATDKPFDVNGSTFVNKGAALQRSCSVQNNACSDAANSGAEDITVADCQAQEDECLAAASLKKLRRSSGGHRMRIASRQALDFGSCQDPSIEFAAGLDGRKEESFAPAGDFEHGSALNINVISSFICGQLQSKCKADAAAVDACKQGQAAAQGQKGQAAADAFNSALGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QN96</accession>
    <name>E3QN96_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">GPI-anchored cell wall organization protein Ecm33</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_07478</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
            <location evidence="1">Cell wall</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697361">
        <property type="protein sequence ID" value="EFQ32334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096354.1">
        <property type="nucleotide sequence ID" value="XM_008098163.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QN96"/>
    <dbReference type="STRING" id="645133.E3QN96"/>
    <dbReference type="GeneID" id="24412843"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07478"/>
    <dbReference type="eggNOG" id="ENOG502QUZC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035846_0_1_1"/>
    <dbReference type="OrthoDB" id="536881at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.20.20">
        <property type="entry name" value="Receptor L-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051648">
        <property type="entry name" value="CWI-Assembly_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036941">
        <property type="entry name" value="Rcpt_L-dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31018:SF3">
        <property type="entry name" value="RECEPTOR PROTEIN-TYROSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31018">
        <property type="entry name" value="SPORULATION-SPECIFIC PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0134">Cell wall</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180599" description="GPI-anchored cell wall organization protein Ecm33" evidence="7">
        <location>
            <begin position="22"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="346"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="359"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ32334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="399" mass="41045" checksum="A9EC716A6D8EBC84" modified="2011-01-11" version="1">MYSKVIPALVALGAGVVSAQSANICSSATVTITDAAMATNIPCGTINGAVKIAEDITGNIDINGPKTIKGDLIVTNVTQLVGLSSSTLASVEGTFQLQGLTVLSNLAFTSLTTVGSINWVTLPALGNLVFGTAGVTKVNDILISDTFLKSLDGLNVASVDSLRINNNNQLVSYSNQLANATKTIEINSNGPDLGITLPNLVWAGEIIIADAAKVQMDSLAVVNGSIKFDKNTFTEFIAPNLTQTTDGDVSFINNVELTNLSLPLLTKTGGGLTIQNNTLLAKIDGLPELKQIGGAVLLRGNFTDVALPALDDVKGAFDTQSTGDIDTSCDVFNKMKGRQIQGDYKCRSNNTKANEDGNSSGGNAGGSKNGNGADGAAGMVSVNTAILGAALLFGFAQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPG3</accession>
    <name>E3QPG3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phospholipid-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07895</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697364">
        <property type="protein sequence ID" value="EFQ32751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096771.1">
        <property type="nucleotide sequence ID" value="XM_008098580.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPG3"/>
    <dbReference type="STRING" id="645133.E3QPG3"/>
    <dbReference type="GeneID" id="24413260"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07895"/>
    <dbReference type="eggNOG" id="ENOG502QTA6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028202_0_0_1"/>
    <dbReference type="OrthoDB" id="5594612at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042144">
        <property type="term" value="P:vacuole fusion, non-autophagic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000075">
        <property type="entry name" value="Related to IVY1-phospholipid-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037470">
        <property type="entry name" value="IVY1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38407">
        <property type="entry name" value="PROTEIN IVY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38407:SF1">
        <property type="entry name" value="PROTEIN IVY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="364"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="418"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="434"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="444"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="500" mass="53622" checksum="0AC8EC5A386EECD2" modified="2011-01-11" version="1">METVTTPGGDRPSTPTPSQLPPVPSSPVYSLASTANPLSSYHLPLPPPPRPLHAVLTKSDLELSQAAYSDLIQTAKSYRLALASLSNAASAFGSALESCARLKEARAESLSSASQTGAALSASFTAGAKGACTADLLLSASGVHHLVANHQQILSETVYRDFEVPLLHELDKWRQRVEDEEEAYLREVKARNLEIRRLEKEGLKLHKQRRRDVGSFRAHLVDLTTKLDGLTSLHGDHARTLLRESQDTSGRILEASCSLVRAEVDIFESLARKGWSGGGLDELLEKGADLFASDEVGEYPGLGAGSGGSAESAKLFSILPPKSILADAASDVTRHGGHHRGDSLLSDPDRYQSLTAAAAAANATASSGLGDDNDADSIFSETNFNRPRGVRPFSPQPIRRHATDVTFDSLGVGLGEGSQRDDRAAEETRHDVLREEDEAETYEQTDRSPWEEEVQHRGKGGHGAESGNTAAVEDADAANGTAERGRLGRRWGVNEEEDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPM6</accession>
    <name>E3QPM6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Beta-glucosidase cel3A</fullName>
            <ecNumber evidence="4">3.2.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Beta-D-glucoside glucohydrolase cel3A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Cellobiase cel3A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Gentiobiase cel3A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">GLRG_07947</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="4"/>
    <dbReference type="EMBL" id="GG697365">
        <property type="protein sequence ID" value="EFQ32803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096823.1">
        <property type="nucleotide sequence ID" value="XM_008098632.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPM6"/>
    <dbReference type="STRING" id="645133.E3QPM6"/>
    <dbReference type="GeneID" id="24413312"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07947"/>
    <dbReference type="eggNOG" id="ENOG502QR4D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004542_2_0_1"/>
    <dbReference type="OrthoDB" id="416222at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.300:FF:000002">
        <property type="entry name" value="Probable beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1700:FF:000003">
        <property type="entry name" value="Probable beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF29">
        <property type="entry name" value="BETA-GLUCOSIDASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178716" description="Beta-glucosidase cel3A" evidence="15">
        <location>
            <begin position="20"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type III-like" evidence="16">
        <location>
            <begin position="799"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="742"/>
            <end position="774"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00070030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00078013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00083231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00083611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EFQ32803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="876" mass="94137" checksum="9E8ED1ED52306AF9" modified="2011-01-11" version="1">MRSQTLAVALLAAADQVAAAVTTERQLHKRDLAYSPPVYPSPWMDPNADGWTDAYAKAKDFVSQLTLLEKVNLTTGVGWQGDLCVGNVGSVPRLGLRGLCMQDGPVGIRFSDYNSVFPSGQTAAATWDRELIYRRAEAIGFEHRAKGVDVVLAPVAGPIGRAPAGGRNWEGFSSDPYLTGVAMAESVKGIQQHAIACAKHFIGNEQEHFRQAPEAIGYNYTIDESISSNIDDKTLHELYLWPFQDAVAAGVGSFMCSYNQVNNSYGCQNSKLMNGILKDELGFQGFIMSDWSAGVATAVAGLDMAMPGDTAFNSGMTFWGTNLTVAVLNGTLPEYRLDDMAMRIMAAFFKVGFELNEVPEINFSSWTTDTVGPLQYYAKENVQVINQHVDVRRGQEHGKLIREIAAKATVLLKNEGALPLKKPKFLAVIGEDAGPNLSGPNGCSDHGCNEGTLGAGWGSGTSNYPYLITPDQALQARAVAEGSRYESILSNYDFAATTALVTQPDATAIVFVNADSGEGYIDVGGNEGDRQNLTLWNGGDELVKNVAAGNNNTIVVIHSVGPVLLADMKNNPNITAIVWAGLPGQESGNSITDVLYGDVNPGGKSPFTWGPTRESYGTDVLYEPNNGEGAPQDDFSEGVFIDYRYFDRATSGSNETSTGAAPVYPFGFGLSYTTFEYSNLVVTPKEAGEYTPTTGVTEKAPTFGNYSTDPAAYVFPSGEFRYIYNFIYPYLNTTDISKSANDPAYGQTADEFLPPKALESGPQPKHPASGAPGGNPQLWDVLYTVTATITNKGDVAGDEVAQLYVSLGGPNDPVKVLRGFDRIGIAPGESATFTADITRRDLSNWDTVSQNWVISKYPKKVWVGGSSRELPLSASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPX5</accession>
    <name>E3QPX5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">coproporphyrinogen oxidase</fullName>
            <ecNumber evidence="4">1.3.3.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_08057</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the aerobic coproporphyrinogen-III oxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.3" evidence="4"/>
    <dbReference type="EMBL" id="GG697366">
        <property type="protein sequence ID" value="EFQ32913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096933.1">
        <property type="nucleotide sequence ID" value="XM_008098742.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPX5"/>
    <dbReference type="STRING" id="645133.E3QPX5"/>
    <dbReference type="GeneID" id="24413422"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08057"/>
    <dbReference type="eggNOG" id="KOG1518">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026169_0_0_1"/>
    <dbReference type="OrthoDB" id="15318at2759"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00322"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004109">
        <property type="term" value="F:coproporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1500.10:FF:000002">
        <property type="entry name" value="oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1500.10">
        <property type="entry name" value="Coproporphyrinogen III oxidase, aerobic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001260">
        <property type="entry name" value="Coprogen_oxidase_aer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036406">
        <property type="entry name" value="Coprogen_oxidase_aer_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003727">
        <property type="entry name" value="PRK05330.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10755">
        <property type="entry name" value="COPROPORPHYRINOGEN III OXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10755:SF0">
        <property type="entry name" value="OXYGEN-DEPENDENT COPROPORPHYRINOGEN-III OXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01218">
        <property type="entry name" value="Coprogen_oxidas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00073">
        <property type="entry name" value="COPRGNOXDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102886">
        <property type="entry name" value="Coproporphyrinogen III oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ32913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="408" mass="46372" checksum="ED9480DCA4AA331B" modified="2011-01-11" version="1">MAFTRHTHRLLAQLSSSRTRIAITNQQQLQLGRRLVSSSSKSQFKSHSSGAFLIGAIGLAAAAPLAYKMAVQEPFQLDPPTLAERDALTKQDAEITADSPMRLRMEKFIKEQQQIIVKELEKVDGGKFRRDEWSRKEGGGGITCVLQDGNVFEKGGVGVSVVYGTLPKPAIAKMRVNHKNLDADVDSLPFFAAGLSMVLHPKNPMAPTVHLNYRYFETSNPDGTPQAWWFGGGSDLTPSYLFDEDAVHFHKTLKETCDAHDKSYYPRFKKWCDEYFYNKHRGECRGIGGIFFDDLDETEKDRENTFAFIQDCLKSFLPGYLPILEKRKDMPFNEAEKDWQQIRRGKYVEFNLVHDRGTAFGLNTPGSRVESILMSLPLTASWKYMHEPEPKSREQRLVDVLKAPKEWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQ22</accession>
    <name>E3QQ22_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">WW domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_08104</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697366">
        <property type="protein sequence ID" value="EFQ32960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096980.1">
        <property type="nucleotide sequence ID" value="XM_008098789.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQ22"/>
    <dbReference type="STRING" id="645133.E3QQ22"/>
    <dbReference type="GeneID" id="24413469"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08104"/>
    <dbReference type="eggNOG" id="ENOG502S9K3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060150_0_0_1"/>
    <dbReference type="OrthoDB" id="2530521at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="17"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="147"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="180"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ32960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="325" mass="34053" checksum="46327C0A04552929" modified="2011-01-11" version="1">MADDFAPPAGPPPPKAPEVPPGWAARWNDQYKEWFYVNLHTKQSQWDKPTEPALPPPPPAADAHPGGPPPGYAPRPGDSTPPVDQKVNPYDQKQNPYEDQSSAPQPYGASSSNAISEDERLARQLQAEEEARARGANSNSPMPPGYNPQQQQQSQSPFPDQLPPRAQDTRGKSGGGGFLGKLLGKSKTGSQGQPQYGGYPPQQQQYGGYPPQQQYGGYPPQQQYGGYPPQQGYGGYPPQQGYGGYPPQQGYGPPGGYGMQGGGGRKPGGGGGMGMAGGLALGAGAGLLGGALLADHINDEQQEAYADGYNDGQDGDDFGGGDGDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQH0</accession>
    <name>E3QQH0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08252</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697367">
        <property type="protein sequence ID" value="EFQ33108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097128.1">
        <property type="nucleotide sequence ID" value="XM_008098937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQH0"/>
    <dbReference type="GeneID" id="24413617"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08252"/>
    <dbReference type="eggNOG" id="ENOG502RJMG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1556448_0_0_1"/>
    <dbReference type="OrthoDB" id="3553044at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ33108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="162" mass="18442" checksum="325AFE6B71930D48" modified="2011-01-11" version="1">MFGRQQRTQFSKRSSSGCSWPESDSDDDIVIRPCASDEKADASVTMTEYVPSSTAVGMEQPTSSRPSLTGRRSSAEDAKLEALWECMLELQQKYHCYNSTRMEIAADSEDAMGMMPTKYCMDMLNDSIESLPEEGWKKLSKFLVTDFDTCQKSQKWKFWKHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQR7</accession>
    <name>E3QQR7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08349</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697368">
        <property type="protein sequence ID" value="EFQ33205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097225.1">
        <property type="nucleotide sequence ID" value="XM_008099034.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQR7"/>
    <dbReference type="GeneID" id="24413714"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08349"/>
    <dbReference type="eggNOG" id="ENOG502RAI6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_190133_0_0_1"/>
    <dbReference type="OrthoDB" id="5221152at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ33205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="68" mass="7397" checksum="8FCC0AE42FE2509A" modified="2011-01-11" version="1">MPSSDVQKDQLQSVLERKGIRFHVKTGGAKYECHLQDRSSYERIKAARANSSASQASSSSASTVSSNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQZ9</accession>
    <name>E3QQZ9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ribonucleoside-diphosphate reductase</fullName>
            <ecNumber evidence="3">1.17.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_08431</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ribonucleoside diphosphate reductase small chain family.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.1" evidence="3"/>
    <dbReference type="EMBL" id="GG697369">
        <property type="protein sequence ID" value="EFQ33287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097307.1">
        <property type="nucleotide sequence ID" value="XM_008099116.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQZ9"/>
    <dbReference type="STRING" id="645133.E3QQZ9"/>
    <dbReference type="GeneID" id="24413796"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08431"/>
    <dbReference type="eggNOG" id="KOG1567">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035339_2_1_1"/>
    <dbReference type="OrthoDB" id="10248373at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009263">
        <property type="term" value="P:deoxyribonucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01049">
        <property type="entry name" value="RNRR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.620.20:FF:000004">
        <property type="entry name" value="Ribonucleoside-diphosphate reductase subunit M2 B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.620.20">
        <property type="entry name" value="Ribonucleotide Reductase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012348">
        <property type="entry name" value="RNR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033909">
        <property type="entry name" value="RNR_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030475">
        <property type="entry name" value="RNR_small_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000358">
        <property type="entry name" value="RNR_small_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23409">
        <property type="entry name" value="RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SMALL CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23409:SF18">
        <property type="entry name" value="RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SUBUNIT M2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00268">
        <property type="entry name" value="Ribonuc_red_sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00368">
        <property type="entry name" value="RIBORED_SMALL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0215">Deoxyribonucleotide synthesis</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="387"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="391"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ33287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="413" mass="46860" checksum="F890C57996162DB3" modified="2011-01-11" version="1">MSVEVTPSKQAAAALDSFKMESPVKKLNFNAADKENQPLASDVAPATENTDLQTKPTQEIAKQEAKPVVVPGIKEQEMDEPLLQENGQRFVLFPIKYHEIWQMYKKAEASFWTAEEIDLSKDLHDWNNKINEDEKYFISHILAFFAASDGIVNENLVERFSGEVQVPEARCFYGFQIMMENIHSETYSLLIDTYIKEPAQRTYLFNAIDTIPCIRKKADWALKWISDEKSSFAQRLVAFAAVEGIFFSGAFASIFWLKKRGLMPGLTFSNELISRDEGLHTDFACLLYSHLKNRPSKQVIQDIIVDAVQIEQEFLTEALPCALLGMNSNLMKQYIEFVADRLLVALGNDKVYKSSNPFDFMENISLGGKTNFFEKRVADYQKAGVMNSTKKAQEETTEGKGENGGDFAFDEDF</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2011-05-03" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QR43</accession>
    <name>CBPYA_COLGM</name>
    <protein>
        <recommendedName>
            <fullName>Carboxypeptidase Y homolog A</fullName>
            <ecNumber>3.4.16.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">CPYA</name>
        <name type="ORF">GLRG_08475</name>
    </gene>
    <organism>
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Vacuolar carboxypeptidase involved in degradation of small peptides. Digests preferentially peptides containing an aliphatic or hydrophobic residue in P1' position, as well as methionine, leucine or phenylalanine in P1 position of ester substrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>Release of a C-terminal amino acid with broad specificity.</text>
            <dbReference type="EC" id="3.4.16.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase S10 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.5"/>
    <dbReference type="EMBL" id="GG697369">
        <property type="protein sequence ID" value="EFQ33331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097351.1">
        <property type="nucleotide sequence ID" value="XM_008099160.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QR43"/>
    <dbReference type="SMR" id="E3QR43"/>
    <dbReference type="STRING" id="645133.E3QR43"/>
    <dbReference type="ESTHER" id="colgm-cbpya">
        <property type="family name" value="Carboxypeptidase_S10"/>
    </dbReference>
    <dbReference type="GlyCosmos" id="E3QR43">
        <property type="glycosylation" value="2 sites, No reported glycans"/>
    </dbReference>
    <dbReference type="EnsemblFungi" id="EFQ33331">
        <property type="protein sequence ID" value="EFQ33331"/>
        <property type="gene ID" value="GLRG_08475"/>
    </dbReference>
    <dbReference type="GeneID" id="24413840"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08475"/>
    <dbReference type="eggNOG" id="KOG1282">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008523_10_4_1"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000328">
        <property type="term" value="C:fungal-type vacuole lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.410:FF:000001">
        <property type="entry name" value="Carboxypeptidase Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008442">
        <property type="entry name" value="Propeptide_carboxypepY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF113">
        <property type="entry name" value="SERINE CARBOXYPEPTIDASE CTSA-4.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05388">
        <property type="entry name" value="Carbpep_Y_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0121">Carboxypeptidase</keyword>
    <keyword id="KW-1015">Disulfide bond</keyword>
    <keyword id="KW-0325">Glycoprotein</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0645">Protease</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0732">Signal</keyword>
    <keyword id="KW-0926">Vacuole</keyword>
    <keyword id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="propeptide" id="PRO_0000407447" evidence="1">
        <location>
            <begin position="18"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_0000407448" description="Carboxypeptidase Y homolog A">
        <location>
            <begin position="131"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="271"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="463"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="521"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="2">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="2">
        <location>
            <position position="510"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="184"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="318"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="342"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="349"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="387"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="4"/>
    <sequence length="545" mass="60571" checksum="BE47D30082A91640" modified="2011-01-11" version="1" precursor="true">MRFSTSALVLGAASTAVALDQQVLGGNESPFDSIKVAGQEWLSTFEEKFGKMTTEAKAVWDEITLLAPDAVESFKKNAIPPKPKPAHRKSDKKWDHVVKGADVQSMWVEKNGEKHRKIAGDLKNFNLRAKKVDPSALGIDKVKQYSGYLDDEENDKHLFYWFFESRNDPKNDPVVLWLNGGPGCSSLTGLFMELGPASVDKKLKIVNNEWSWNNNASVIFLDQPVNVGYSYSGSSVSNTVAAGKDVYALLSLFFHQFPEYSKQDFHIAGESYAGHYIPVFASEILSHEDRNINLKSVLIGNGLTDGLTQYGYYRPMACGEGGYPAVLDAGECQAMDNALPRCQSLINNCYESGSVWSCVPASIYCNNALIGPYQRTGQNVYDIRGKCEDSSNLCYSALGWISEYLNQDEVKEALGAEVDSYDSCNFDINRNFLFAGDWFQPFHRIVPKLLEKIPVLIYAGDADYICNWLGNRAWTEALEWPGQKGFNKAEVKSLAVGKGKEYGKVKSSGNFTFMQLYGAGHMVPMDQPEASSDFLNRWLGGEWVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3QS63</accession>
    <name>E3QS63_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Condensation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_08630</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697372">
        <property type="protein sequence ID" value="EFQ33701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097721.1">
        <property type="nucleotide sequence ID" value="XM_008099530.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QS63"/>
    <dbReference type="GeneID" id="24413995"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08630"/>
    <dbReference type="HOGENOM" id="CLU_029138_1_0_1"/>
    <dbReference type="OrthoDB" id="2548233at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42034">
        <property type="entry name" value="CHROMOSOME 7, WHOLE GENOME SHOTGUN SEQUENCE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42034:SF1">
        <property type="entry name" value="CONDENSATION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ33701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="460" mass="50659" checksum="613DDF76F2979676" modified="2011-01-11" version="1">MAVTAEQSDLQWAKTSSRTYERSLDDMENFFRLAGEGGVGATDGQHWHIAVMAKIKATGIDLRKDILTAWKALRRINPFLSAIVRDGRWIYTVADEKELEPWLKESLHFHDTFSTTRDMFPIRNFTGRAALHVLLQTQELYLLAPHTHLDGIGAYTAMSNLVQALADAASVTNNPELGGDEAHNLVPPLNILADIPVATDADRNTFKSMLGGWMASFAGVKLQHDNSTKQPCGDPKILYAPFSVSESDRIVARCKELGFTVTAAVQAAVSTALRKQVNSTASIQSAVTIHDVRKWVDKTKYPATALVGALAIPVPAVFTLGDDFLETARLARQRYLEPDQTGLLRKLPRFWGHDMVALMTSPPPGAEAPSSLGLSSFGVMDKYIQPSYQSVDGGKAQVEVEDAWLGITLYSPDILLHLWTLQGAMRLQFVYNEAYFEKESIAALLKSTQDELLLGLGLMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSN9</accession>
    <name>E3QSN9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">aldehyde dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="4">1.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_09021</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="4"/>
    <dbReference type="EMBL" id="GG697374">
        <property type="protein sequence ID" value="EFQ33877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097897.1">
        <property type="nucleotide sequence ID" value="XM_008099706.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSN9"/>
    <dbReference type="STRING" id="645133.E3QSN9"/>
    <dbReference type="GeneID" id="24414386"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09021"/>
    <dbReference type="eggNOG" id="KOG2450">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_0_0_1"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046394">
        <property type="term" value="P:carboxylic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006598">
        <property type="term" value="P:polyamine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000050">
        <property type="entry name" value="Aldehyde dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000026">
        <property type="entry name" value="Aldehyde dehydrogenase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000012">
        <property type="entry name" value="Betaine aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43720">
        <property type="entry name" value="2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43720:SF2">
        <property type="entry name" value="2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="7">
        <location>
            <begin position="28"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ33877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="501" mass="53830" checksum="D0AD1E7F7D3E3D80" modified="2011-01-11" version="1">MSAATLDLTAPNGTKISLPTGLFINNEFVKGNSDSKITAINPSNESEIASVEAASADDVDRAVKAARAALNAPGWGDISNTDRGRLMFKLADLVEKHEAALATLETWNGGKPYNVALGEDVAETIATLRYYAGWADKIHGETIPTTPKKFAYTLKQPIGVCASIIPWNYPIMMAAWKLGPALACGNTVIMKPAEQTPLSILYFANLVKEAGFPAGVINIVNGFGREAGHALASHPDVDKVAFTGSTTTGRQIMKAASANIKNITLETGGKSPLLVFKDADLDQAAKWGHVGIMSNQGQICTSTSRILVQEEVYQDYVSRFKKICLENKVGDPFDDDTFQGPQITKAQYEKILSYIQAGKDEGASLVTGGVPYKNVGDGKGFFIEPTVFSDVKKDMRIFQEEVFGPFVAITPFKTEEEAVSLANNTSYGLGAALFSRDIERCHRVAARLESGMVWINSSNDSDIRVPFGGVKQSGIGRELGEAGLAAYSQTKAVHVNLGYVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>E3QT70</accession>
    <name>E3QT70_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">rRNA methyltransferase 2, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_09202</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697376">
        <property type="protein sequence ID" value="EFQ34058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098078.1">
        <property type="nucleotide sequence ID" value="XM_008099887.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QT70"/>
    <dbReference type="STRING" id="645133.E3QT70"/>
    <dbReference type="GeneID" id="24414567"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09202"/>
    <dbReference type="eggNOG" id="KOG4589">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009422_2_0_1"/>
    <dbReference type="OrthoDB" id="20105at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008650">
        <property type="term" value="F:rRNA (uridine-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01547">
        <property type="entry name" value="RNA_methyltr_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050082">
        <property type="entry name" value="RNA_methyltr_RlmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002877">
        <property type="entry name" value="RNA_MeTrfase_FtsJ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015507">
        <property type="entry name" value="rRNA-MeTfrase_E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10920">
        <property type="entry name" value="RIBOSOMAL RNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10920:SF18">
        <property type="entry name" value="RRNA METHYLTRANSFERASE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01728">
        <property type="entry name" value="FtsJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribosomal RNA methyltransferase FtsJ" evidence="8">
        <location>
            <begin position="67"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="140"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="149"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="159"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00041184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ34058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="328" mass="36143" checksum="CAC5838B9EAC6B12" modified="2011-01-11" version="1">MSKAAACRALLGVTQRQTTMNAVSGCLQCRINLAASRQTRASSSNSRWKMRQGRDMFAREAKVQGLKSRAAFKLLEMDAKYKLFRKGQTVVDLVAVERTKPNGQILGIDIIPAQPPKGVSTIQGNFLSPDVQDMVKEYLSRAKSRKSSSPPPPPPPPSSEEDQQDDADAVMDDRPSYIDMERAASETVAEAEAPPNAANGAEAKKGRLVDVVLSDMSAPWDQTSGFGVNSLSNPYSRMMNTSGMAFRDHAGSMDLCGVALQFANDTLRNGGHFVCKFYQGSEDREFEKKLKTLFAKVFREKPESSRSDSKEAYFVALRRKGNVELERD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTF1</accession>
    <name>E3QTF1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09283</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697377">
        <property type="protein sequence ID" value="EFQ34139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098159.1">
        <property type="nucleotide sequence ID" value="XM_008099968.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTF1"/>
    <dbReference type="GeneID" id="24414648"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09283"/>
    <dbReference type="eggNOG" id="ENOG502TCXZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2512501_0_0_1"/>
    <dbReference type="OrthoDB" id="5339708at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180786" evidence="1">
        <location>
            <begin position="23"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="85" mass="8976" checksum="0C17AD4D2FE5AF6D" modified="2011-01-11" version="1">MHLSTSLFATVLAFAAFDQAAAICYWDSCCYTNTNGPGACPPQLWKVSFTSSYCAVSICPLPCTNLADGSACDCCDIATGKCRKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTI7</accession>
    <name>E3QTI7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Microbial-type PARG catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_09319</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697377">
        <property type="protein sequence ID" value="EFQ34175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098195.1">
        <property type="nucleotide sequence ID" value="XM_008100004.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTI7"/>
    <dbReference type="STRING" id="645133.E3QTI7"/>
    <dbReference type="GeneID" id="24414684"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09319"/>
    <dbReference type="eggNOG" id="ENOG502S1YN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024412_1_0_1"/>
    <dbReference type="OrthoDB" id="2440523at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="entry name" value="Leucine Aminopeptidase, subunit E, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012664">
        <property type="entry name" value="CHP02452"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019261">
        <property type="entry name" value="PARG_cat_microbial"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02452">
        <property type="entry name" value="TIGR02452 family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35596">
        <property type="entry name" value="DUF2263 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35596:SF2">
        <property type="entry name" value="MICROBIAL-TYPE PARG CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10021">
        <property type="entry name" value="PARG_cat_microb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Microbial-type PARG catalytic" evidence="2">
        <location>
            <begin position="57"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="280"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ34175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="343" mass="38773" checksum="1317828A6F3E5CE2" modified="2011-01-11" version="1">MPSSKPLKIKPSEVAADTKKKLIPEVNRHFREEWPPYSILYAQPLLQLHLTRPSFISSDLPKFYVVHSDPVDCALGWAQTEGVRIPFICAANEKRPGGDWETGVVGYEERLCRRSNLSATLGTPHPESYQATNYPIPIEGAIYSPDVVRFRQFQDRIESLDMKDWRSLPVISMPPARWPKLTDHGRKYSFSEERELVRNKMRAALRICVFNGYNHVVIGDFGLGNGYRNPPKELAELWRDVFLYDPELRGQFLAVMFAFEDDRQCTAKYILDDIAKKTKGTSSSSSSKSKSKSSSSSSGSSSSSSSHKSDFKIFSEIFAPNEIARVRSQPDPRYAFSAIMDGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTN8</accession>
    <name>E3QTN8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Pyrroline-5-carboxylate reductase</fullName>
            <ecNumber evidence="9">1.5.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_09344</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-proline + NADP(+) = (S)-1-pyrroline-5-carboxylate + NADPH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:14109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17388"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="EC" id="1.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the pyrroline-5-carboxylate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.2" evidence="9"/>
    <dbReference type="EMBL" id="GG697378">
        <property type="protein sequence ID" value="EFQ34200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098220.1">
        <property type="nucleotide sequence ID" value="XM_008100029.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTN8"/>
    <dbReference type="STRING" id="645133.E3QTN8"/>
    <dbReference type="GeneID" id="24414709"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09344"/>
    <dbReference type="eggNOG" id="KOG3124">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042344_0_1_1"/>
    <dbReference type="OrthoDB" id="10263291at2759"/>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00361"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004735">
        <property type="term" value="F:pyrroline-5-carboxylate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3730.10:FF:000001">
        <property type="entry name" value="Pyrroline-5-carboxylate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000105">
        <property type="entry name" value="Pyrroline-5-carboxylate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.10">
        <property type="entry name" value="ProC C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01925">
        <property type="entry name" value="P5C_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053790">
        <property type="entry name" value="P5CR-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029036">
        <property type="entry name" value="P5CR_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000304">
        <property type="entry name" value="Pyrroline-COOH_reductase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00112">
        <property type="entry name" value="proC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645">
        <property type="entry name" value="PYRROLINE-5-CARBOXYLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645:SF0">
        <property type="entry name" value="PYRROLINE-5-CARBOXYLATE REDUCTASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14748">
        <property type="entry name" value="P5CR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000193">
        <property type="entry name" value="Pyrrol-5-carb_rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00521">
        <property type="entry name" value="P5CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 9" id="KW-0521">NADP</keyword>
    <keyword evidence="7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 9" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyrroline-5-carboxylate reductase catalytic N-terminal" evidence="10">
        <location>
            <begin position="9"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Pyrroline-5-carboxylate reductase dimerisation" evidence="11">
        <location>
            <begin position="174"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="13"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>NADPH</name>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="73"/>
            <end position="76"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000193-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ34200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="285" mass="29637" checksum="85A56286A42D20EF" modified="2011-01-11" version="1">MAPTLESSKIAFIGGGNMAAAIIGGLVAKGIDKQHVTVSEPWEVNREKMAALGVKTTTSNAEAFVGADIAILAVKPQVAKGVCNELAKAVSGHDKTPVVVSIAAGITLEALQKWLTLDDGRTPHVVRVMPNTPALVGEGASGLFAGSDVTKEEKELTESLMASVSKATEWVEKEELIDVVTGLSGSGPAYFFAMVEHLISSAVSLGLSPEQAKRLATQTCLGAGKMLVESSEDPSQLRKNVTSPNGTTYAALQSFEASGFKDIVDKAVKAATSRGEELGKTLGNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTZ8</accession>
    <name>E3QTZ8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Fungal specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_09480</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697379">
        <property type="protein sequence ID" value="EFQ34336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098356.1">
        <property type="nucleotide sequence ID" value="XM_008100165.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTZ8"/>
    <dbReference type="STRING" id="645133.E3QTZ8"/>
    <dbReference type="GeneID" id="24414845"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09480"/>
    <dbReference type="eggNOG" id="ENOG502S0D7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008511_0_2_1"/>
    <dbReference type="OrthoDB" id="3364175at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000435">
        <property type="term" value="P:positive regulation of transcription from RNA polymerase II promoter by galactose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051127">
        <property type="entry name" value="Fungal_SecMet_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424:SF3">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="18"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ34336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="744" mass="82794" checksum="F46369A82EBF8FD9" modified="2011-01-11" version="1">MPGSSDATTRKRKRIPIACNSCRVRKSRCDGARPQCSTCVEQGLDCVYAANSGASNALVPKQYLEQVELRLADVEEEISRLKRLIPHSFSDEKQHATVSHRNSCRADDCSESAQAGESLNAENRSITGITPDTTDGVGTIEFTTDESWAYFGPSSNIAFMRIIRRTLDHLLRQTQRTQEGVTSSTPLQNTEQHVLAVSRSQSPIDDSFDPRKLETASEASRLPPEDEVIRLVRQYFGDAGILFPYIHEESFWKAFAYYRSIGMRNARHSWLALLNIIIAVAHSTTSSANIGLGDRQAISDVHYRRAKSLFMTEMMTGSNLESVQAMLLMSQYLQGSQRSVQTWSIHGLAVKAALELGFHSELALQRFEPLERETRIRTWYGCILLDRTLSMTFGRPPIIPQHMIRIPLPQHFISYPKVPSISRWSREEDSTLFWNASITLYGVTAAVIENLYESNVGSTSAVSVTHIVSSVIHIGQKLGDWQASLPLSMRLVEPSEVANPDAKPVQLKLRVVLTLRHHNLQILLHRPILDRCLQALDGGTKSTQEAATLEQAWHLSKTVCLRSAEATIRLVEACKLANDAQPTFSFLGAWWFTLYFTFNASLTIIALKLIEDSYASTPYNHSYAGTVAKLEETLKSAVSCIARIDTKNPTVEKCAKFTATLILTVQSLHMGRDDANVLSSSTTTITDENGVNQNTQILNNGGLDEAFSDLVNYLPQNFNDFSAASAPFAMSELMNDSSTGDLFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QU39</accession>
    <name>E3QU39_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alcohol dehydrogenase GroES-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_09521</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697379">
        <property type="protein sequence ID" value="EFQ34377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098397.1">
        <property type="nucleotide sequence ID" value="XM_008100206.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QU39"/>
    <dbReference type="STRING" id="645133.E3QU39"/>
    <dbReference type="GeneID" id="24414886"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09521"/>
    <dbReference type="eggNOG" id="KOG1198">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1468058_0_0_1"/>
    <dbReference type="OrthoDB" id="10257049at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047122">
        <property type="entry name" value="Trans-enoyl_RdTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348:SF7">
        <property type="entry name" value="ZINC BINDING OXIDOREDUCTASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="3">
        <location>
            <begin position="33"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ34377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="184" mass="19525" checksum="C0AAA72C628F6FE0" modified="2011-01-11" version="1">MSETPPSSAHALYVDKDCNLKAIRNVPVPELVDGEVVVKVLYSGVNSADVKHGPILGVRPTILGYDFCGRVAQSAPTSGFRVGDLVAVFTPTGVGKPSRYGAHQEYLSCPENFMYKVPENLPPTHAASLTTVAPTAADGLYNIGLPNSQYVRQAEESFEDVAYLSSVLSPCGFPKALICLQGPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUX4</accession>
    <name>E3QUX4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09806</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697382">
        <property type="protein sequence ID" value="EFQ34662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098682.1">
        <property type="nucleotide sequence ID" value="XM_008100491.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUX4"/>
    <dbReference type="GeneID" id="24415171"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09806"/>
    <dbReference type="eggNOG" id="ENOG502T4AE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_605514_0_0_1"/>
    <dbReference type="OrthoDB" id="4833950at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="102"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="452" mass="49549" checksum="024A86A8945F817A" modified="2011-01-11" version="1">MNTSPEEPKPARTAAMESTPSSSSHAAVDAQASGKRKRSPVEPTTTRSAPSSSNQAAVDTQASRKRKPLPVEPTTARSAPSSSNQAAVDAQASIERQPIPVEPTTTVSASPSSTQAGVDVQTPAGCKYAVNGHCAIRSLTYYLGVLSSEEVHTEDRMYHANIFCDAVTTGPRFVCTFQVCCGNISLLSFAVERRFPMEVLEFLLTNTRFRQEDGCRIIDFVEHIGSLIVCLMYGYSGRCFNNSLLDDAKRSLRLLLRAGTQNAFARRIWHNNGQYRTWILSVLHAASVYVSPIPSEPGQPYITRVVPILALLHLVECFMEMFPDEDASFWSVVLQELWMHSRITRGTLRRVADMTLRLLDLGASTTFALPDRAKGGSFLACLENGLEAVEDVNPYVDDIEATIGGTKIMEFGGPGQAIDIIRNRMYGKRIESIERLKKKILGDGSLSPPSVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVY3</accession>
    <name>E3QVY3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Voltage-gated hydrogen channel 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Hydrogen voltage-gated channel 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">GLRG_10165</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697387">
        <property type="protein sequence ID" value="EFQ35021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099041.1">
        <property type="nucleotide sequence ID" value="XM_008100850.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVY3"/>
    <dbReference type="STRING" id="645133.E3QVY3"/>
    <dbReference type="GeneID" id="24415530"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10165"/>
    <dbReference type="eggNOG" id="ENOG502QQMU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076372_1_2_1"/>
    <dbReference type="OrthoDB" id="427456at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034702">
        <property type="term" value="C:monoatomic ion channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030171">
        <property type="term" value="F:voltage-gated proton channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="entry name" value="Voltage-gated potassium channels. Chain C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031846">
        <property type="entry name" value="Hvcn1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46480">
        <property type="entry name" value="F20B24.22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46480:SF1">
        <property type="entry name" value="VOLTAGE-GATED HYDROGEN CHANNEL 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="49"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="92"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="14">
        <location>
            <begin position="49"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EFQ35021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="197" mass="22639" checksum="30DBB9F7014DFEE8" modified="2011-01-11" version="1">MASDEEPSRPLLWSFSGFRENRRPTPLSRQLSQSRISLQDMLSSRRKHYVILALVFLDVATLMANIFVELVACDMKRDDEPWVKSTRQGLTLAGLVFSCVFLAELILCVTAFGWRYFHDWFHVLDGLVIVVSFTVDVLSHGIVEEIASLVIVFRLFRFVKLVEEMSMGAVERTEGLEELLVTLKRENGELKRQLAMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWN3</accession>
    <name>E3QWN3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Peroxisomal ATPase PEX1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Peroxin-1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">GLRG_10415</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697390">
        <property type="protein sequence ID" value="EFQ35271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099291.1">
        <property type="nucleotide sequence ID" value="XM_008101100.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWN3"/>
    <dbReference type="STRING" id="645133.E3QWN3"/>
    <dbReference type="GeneID" id="24415780"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10415"/>
    <dbReference type="eggNOG" id="KOG0735">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000688_1_0_1"/>
    <dbReference type="OrthoDB" id="2187at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016558">
        <property type="term" value="P:protein import into peroxisome matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19526">
        <property type="entry name" value="RecA-like_PEX1_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000149">
        <property type="entry name" value="Nuclear valosin-containing protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.330.10:FF:000011">
        <property type="entry name" value="Peroxisome biogenesis protein peroxin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029067">
        <property type="entry name" value="CDC48_domain_2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015342">
        <property type="entry name" value="PEX1-N_C-lobe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF12">
        <property type="entry name" value="PEROXISOMAL ATPASE PEX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09262">
        <property type="entry name" value="PEX-1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="ADC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54585">
        <property type="entry name" value="Cdc48 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="14">
        <location>
            <begin position="545"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="14">
        <location>
            <begin position="876"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="235"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="714"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1078"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="241"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="721"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="747"/>
            <end position="756"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EFQ35271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1215" mass="130663" checksum="800D89A2872D019C" modified="2011-01-11" version="1">MASRRNAQSTPAEISLAHLKNCLVNLPASLVSLLVNLNTPAQNVVVELSYRPSTSVSGSGTSQQRSIFVGWTGMPSKRKVAPIVGREGINGGRGGTSSRDQEFAQVELDATLANTLGLTDGQKITASIHVDPPVAHTINIEPLTPEDWEMIELHATFLELNLLSQVRALPNPAFTSSSGSLVPPHALTLHLSPTSTANVRVVSLDPAPAADVPFVKISPDAEVIVAPKVRAKTSHSLGENRSVASTSKSKRSSASTVRRRSAREERKPALCLRGVAYSACTEWFDEDLTTHDFSVWVDRDILYTKDFRGVNYVSVNILRPAQQTSSTQKPQQDVEQSVSTSKVATKVVANLKAWDDPPDSKTIAISPALCSTLGFTASVGGVVKIEPAPQQWPLDAVQKLIIQPFAASKKSSGGLKFGGESKAGKEEASKQFKQIYGGRKDSSSLLTGPLTDGSVLGTFEGLEAPQGWEGGIIKFDPPAINSDPLRSSTRWVLGLSEKVPVDIRDPVPRPSFLNDDGIAELQPHYESRLVGIDKLLQDLRSHLSHLSSALLTGALGSGKTAVARSLAHELGKDLLFHTTYFPCRKLVNDETRIATIKDTLNQVFMSASWGARLGGKALVVLDDLDKLCPVETELQVGNDNGRSRQISEIVGSIVRQYCQVETGVVLLATAEGKDSLNNVIIGGHVVREIVDLKAPNKEARRKVMESIVGQGAVVPGDLPQASRNGSRPTTADRSAAGEDSAWMDAGSQGSQENRTSVTGGFVLDPDLDFLDIAGLTDGYMPGDISLLVARARNEAIIRSVNSASAESSGAVHFSRVDFDNALKGFTPASLRNVSLQHSTTTFSSIGGLQETRKVLLETLQYPTKYAPIFEQCPLRLRSGLLLYGYPGCGKTLLASAVAGECGLNFISVKGPEILNKYIGASEKSVRDLFERASAAKPCVLFFDEFDSIAPKRGHDSTGVTDRVVNQLLTQMDGAEGLSGVYVLAATSRPDLIDPALLRPGRLDKSLLCDMPMLEDRIDILKSLSSKVKLGEELTESDDAWTDIAQKTEGFSGADLQALVSNSQLEAIHDVLGDANHASTANGKVNGKSSPSQGSVPSFVQFRYGQHSTPASKPISRQAELVENAAILAKLESIRLARKRVKHSQRPDGEAKLENDKEVVVKLEHVMKALDNTRSSISAQERARLRRIYHEFVVGRSGEMKDGQGSMEIGGRSSLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QX20</accession>
    <name>E3QX20_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_10552</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697392">
        <property type="protein sequence ID" value="EFQ35408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099428.1">
        <property type="nucleotide sequence ID" value="XM_008101237.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QX20"/>
    <dbReference type="STRING" id="645133.E3QX20"/>
    <dbReference type="GeneID" id="24415917"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10552"/>
    <dbReference type="eggNOG" id="ENOG502T4AH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116807_0_0_1"/>
    <dbReference type="OrthoDB" id="4851748at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="108"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ35408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="165" mass="17494" checksum="A93502C678BD0CE8" modified="2011-01-11" version="1">MYINLQSGGRAPWSLGHRREGRPLEATWPQAFEASVPVAERDTAVTKRQVSISGGQTTNLTVGITVGVAVLLFLLGAGAFIYCYGISLRKIGRRRRRHSRRNRRYQHKSVSSGSSKSSAEGPPASHASRSAPPSAAPANDPPADPPADPPADPPADPPADPPADK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXM8</accession>
    <name>E3QXM8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Amino acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_10760</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697396">
        <property type="protein sequence ID" value="EFQ35616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008101445.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXM8"/>
    <dbReference type="STRING" id="645133.E3QXM8"/>
    <dbReference type="GeneID" id="24416125"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10760"/>
    <dbReference type="eggNOG" id="KOG1289">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004495_2_1_1"/>
    <dbReference type="OrthoDB" id="2417308at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF20">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="47"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="281"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="334"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="384"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="412"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="454"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="482"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ35616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="518" mass="56270" checksum="39F448EA064D9016" modified="2011-01-11" version="1">MAETKSITDIPSSPRKSLDAAAPEKSFDADEARLAQMGHTQELKRHFSTLSLIGLASTTTISWTGLGLGLITEINAGGPGAVIYGFILVTLLQCFLGASLAEFVSSYPTEGGMYHWIAAVAPKKLTGVLSFFTGWFSVLGWIFTTASTNLIYAQILMAMIAVYHGDLEIQAWQTFIVYQGLNLITAAIVMYGNKIIPGLNKFSLFYLQIGWFVVMVTVAACAPTHRNADFVFRTWINNTGWENQVICFITGLVNPLYSLGGLDGVTHITEEMPNPSRNAPLAIAITLGIAFVTGLTYLVTLMFSIQDFDALSTTNTGLPLAELFRQVTQSAGGAFGLTFILFIALGPCVVSSQLSTGRVFWAFSRDGAMPFSKVWSKVHPKWQIPINSQMAVTAIVAALGCLYLGSSTAFNSLLGTAVTINNISYMFPILTNLLTGRRNMHRGVFNMGPTLGPIVNGITVCWLTFAIVFFSFPYVMPVEPANMNYTCVVVGGLAILVGAWWFKAGSKYSEKMLQAKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXP7</accession>
    <name>E3QXP7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Stress responsive A/B Barrel domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_10794</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <dbReference type="EMBL" id="GG697397">
        <property type="protein sequence ID" value="EFQ35650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099670.1">
        <property type="nucleotide sequence ID" value="XM_008101479.1"/>
    </dbReference>
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    <dbReference type="STRING" id="645133.E3QXP7"/>
    <dbReference type="GeneID" id="24416159"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10794"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Dabb"/>
    </dbReference>
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        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044662">
        <property type="entry name" value="HS1/DABB1-like"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33178:SF10">
        <property type="entry name" value="STRESS-RESPONSE A_B BARREL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Dabb"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Dimeric alpha+beta barrel"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS51502">
        <property type="entry name" value="S_R_A_B_BARREL"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Stress-response A/B barrel" evidence="2">
        <location>
            <begin position="3"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ35650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="112" mass="12506" checksum="C8250386462C1D08" modified="2011-01-11" version="1">MSVIHIVQFQFKELVPIDDVKSICDSMLALRDNCIHPTSNKTYIKSIAGGLDTSPEGLQDGITHVFVVEFESSEDRDYYVHKDPAHRAFVEKAGPSILKARVVDFTPGVFII</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>E3QY81</accession>
    <name>E3QY81_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_10928</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697401">
        <property type="protein sequence ID" value="EFQ35819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099839.1">
        <property type="nucleotide sequence ID" value="XM_008101648.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QY81"/>
    <dbReference type="GeneID" id="24416293"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10928"/>
    <dbReference type="HOGENOM" id="CLU_1948681_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ35819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="129" mass="13749" checksum="B8FA536A980F52AE" modified="2011-01-11" version="1">MGGVDTGLAPVRWNRVGHVPLAGVEGGRRQEGAQWTVIGGLQNGEGKTVGCAANLWLVRSERLQLIGQGDLNLTHYPTRPPLGGSVYFATTLLQSKKPFSRYCGRYGTFAALDSPGFPPLFADSSFGAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYF0</accession>
    <name>E3QYF0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glucose-methanol-choline oxidoreductase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_11079</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697402">
        <property type="protein sequence ID" value="EFQ35888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099908.1">
        <property type="nucleotide sequence ID" value="XM_008101717.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYF0"/>
    <dbReference type="STRING" id="645133.E3QYF0"/>
    <dbReference type="GeneID" id="24416444"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11079"/>
    <dbReference type="HOGENOM" id="CLU_002865_8_3_1"/>
    <dbReference type="OrthoDB" id="4773574at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ35888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="59" mass="6141" checksum="846E0A23A7736BA7" modified="2011-01-11" version="1">MAEDGLGGGVVDADLRVKGTSNLRVCDASIFPIIPRGNILTTVYAVAGKASKFILASYK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2011-07-27" modified="2025-02-05" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYP0</accession>
    <name>AMPP3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName>Probable Xaa-Pro aminopeptidase PEPP</fullName>
            <ecNumber>3.4.11.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName>Aminoacylproline aminopeptidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName>Prolidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="primary">PEPP</name>
        <name type="ORF">GLRG_11122</name>
    </gene>
    <organism>
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide.</text>
            <dbReference type="EC" id="3.4.11.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="1">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M24B family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.9"/>
    <dbReference type="EMBL" id="GG697405">
        <property type="protein sequence ID" value="EFQ35978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099998.1">
        <property type="nucleotide sequence ID" value="XM_008101807.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYP0"/>
    <dbReference type="SMR" id="E3QYP0"/>
    <dbReference type="STRING" id="645133.E3QYP0"/>
    <dbReference type="EnsemblFungi" id="EFQ35978">
        <property type="protein sequence ID" value="EFQ35978"/>
        <property type="gene ID" value="GLRG_11122"/>
    </dbReference>
    <dbReference type="GeneID" id="24416487"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11122"/>
    <dbReference type="eggNOG" id="KOG2737">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017266_1_2_1"/>
    <dbReference type="OrthoDB" id="10261878at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01087">
        <property type="entry name" value="Prolidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007865">
        <property type="entry name" value="Aminopep_P_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052433">
        <property type="entry name" value="X-Pro_dipept-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43226">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43226:SF1">
        <property type="entry name" value="XAA-PRO DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05195">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01011">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0031">Aminopeptidase</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0464">Manganese</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0482">Metalloprotease</keyword>
    <keyword id="KW-0645">Protease</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000411871" description="Probable Xaa-Pro aminopeptidase PEPP">
        <location>
            <begin position="1"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="391"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="431"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="431"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="461" mass="51662" checksum="2DEBD8E93DD6D198" modified="2011-01-11" version="1">MTQDYETVLKGKYPAKEHALRVADYVKSKVPDATGILYVEGRMTKMLEDNDEPEPFRQRRYFYYLTGCPLADCHYIFDLATSKSTLFIPPIDPDSVIWSGLPVSAAEAKELYDVDEVKYTTDVNAELARLGKGPKKTVFAIQNQVLDSITFLEFDEKNFSILKDAIERCRVVKDDYEIALTRKANAVSTVAHHAVVEYVKKAKNERELEALFLQRSVANGAKNQAYHGIFAGGRAAATLHYVANDAPLEGKLNLLLDAGTEWNCYASDITRTFPISGKFSKESRQIYDIVLKMQLETTAALKEGVIWDEIHLLAHKIAIDGLHLIGILKGDKDEILKNRTSVAFFPHGLGHYLGMDTHDVGGNANYADRDPMFRYLRVRGALPAGSIVTVEPGIYFCSFIIEPYLKDPVHSKFIDSAVLEKYWDVGGVRIEDNILITKDGSENLTPTIKDPDELEKIIQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYR2</accession>
    <name>E3QYR2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Peroxidase</fullName>
            <ecNumber evidence="12">1.11.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_11144</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9 12">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="9 12">Binds 2 calcium ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="9">Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 12">Belongs to the peroxidase family. Ligninase subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.-" evidence="12"/>
    <dbReference type="EMBL" id="GG697406">
        <property type="protein sequence ID" value="EFQ36000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100020.1">
        <property type="nucleotide sequence ID" value="XM_008101829.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYR2"/>
    <dbReference type="STRING" id="645133.E3QYR2"/>
    <dbReference type="GeneID" id="24416509"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11144"/>
    <dbReference type="eggNOG" id="ENOG502SM0W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041038_1_0_1"/>
    <dbReference type="OrthoDB" id="2113341at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.520.10:FF:000021">
        <property type="entry name" value="Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001621">
        <property type="entry name" value="Ligninase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF66">
        <property type="entry name" value="CATALASE-PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00462">
        <property type="entry name" value="LIGNINASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0106">Calcium</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="4 9 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 12 14" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006991299" description="Peroxidase" evidence="12">
        <location>
            <begin position="18"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="13">
        <location>
            <begin position="123"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="276"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="10">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="100"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="121"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601621-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601621-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601621-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601621-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ36000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="406" mass="43725" checksum="E8198AA58DA535B0" modified="2011-01-11" version="1">MKTASLIGALVAGVAFAHPGMNIKKLIADAELQTRQFGGGGPSTELIGDLVDLRERDLTQTGSAIRDILIAEAPGADVETFYDESELAPRDSEDCASDECCIWKYIADDMAKQMVGNAGRCNSVARGAIRLGFHDAASWSKSTGGTGADGSIILANECKTRSDNKGLEDICDIMSGWYAKYKKYGISMADLIQTGANVGTVSCPLGPRVRTFIGRKDTTTPAVQNLLPDPKDSSEKLFKIFADKSFTPAGLVALLGAHSTSQQRFVDPARAESPQDSTPGTWDIAFYQQTLNPNAPPAVFKFQSDINVSLDPQTNDLWRLFSAGPRGQVAWGKAYAVEYVRMSLLGVNNINDLTECTKVLPPFRPDFQQPDQELLDKVMGGILSSDLVKQALEKGDKIPPAALSNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYZ2</accession>
    <name>E3QYZ2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11224</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697408">
        <property type="protein sequence ID" value="EFQ36080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100100.1">
        <property type="nucleotide sequence ID" value="XM_008101909.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYZ2"/>
    <dbReference type="GeneID" id="24416589"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11224"/>
    <dbReference type="HOGENOM" id="CLU_587934_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="465" mass="52599" checksum="7FB573C5915BADB1" modified="2011-01-11" version="1">METLPPPPCDPSRRPSSKNDRSNRGNDSRNSRDDPDGRDITATSMAESKALLRRRVQKQQQREQQQQQQQQQQQQQREQEQQQQRQEHRSNQQGQWKKPRKHEDASRQPPETKAPQRHGQRPVVVVLQSISRLLRGVWLLLRWLFAHPKLVVIAFAVIAVLCSVGNQASSSSSSSPRSSASRHREVLSPVIPSFPSFSDGISDTAVVVADVINGDPDYALYITPSVMPARNLLDNVDSAIRAFSQRLVQEQTQYLRLIHRTENSPALGQPLRSAWPWTYSRRQAQARDIALGQGRQLGKLIEAALSSRNTLVKTLRSKQTLQATLHVSRNTCNWAKMLETKPQIVAGFVERLTTFEPAKADGPLTNHDVQVRDLVTTEVSRARVLCSGSNVMATSWKRLEEHVVQRDVEDLMSARGQVQHLLEQVVNGSNNLDPDELNEWEARLVDIAVALLKSMRQVYGRYSEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZH7</accession>
    <name>E3QZH7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11410</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697416">
        <property type="protein sequence ID" value="EFQ36265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100285.1">
        <property type="nucleotide sequence ID" value="XM_008102094.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZH7"/>
    <dbReference type="GeneID" id="24416774"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11410"/>
    <dbReference type="eggNOG" id="ENOG502SYKH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_169797_0_1_1"/>
    <dbReference type="OrthoDB" id="3050608at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="73" mass="7639" checksum="B44CFE4DE61180C1" modified="2011-01-11" version="1">MDQIKNLAGGSNGASNTAGAGQQKQDPVDKVFDFGSKKAGHDFSPSTDEKITDAGRGVYEKVTGKKVNPKISN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZV4</accession>
    <name>E3QZV4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">alpha,alpha-trehalase</fullName>
            <ecNumber evidence="3">3.2.1.28</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_11560</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha,alpha-trehalose + H2O = alpha-D-glucose + beta-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:32675"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15903"/>
            <dbReference type="ChEBI" id="CHEBI:16551"/>
            <dbReference type="ChEBI" id="CHEBI:17925"/>
            <dbReference type="EC" id="3.2.1.28"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 65 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.28" evidence="3"/>
    <dbReference type="EMBL" id="GG697422">
        <property type="protein sequence ID" value="EFQ36392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100412.1">
        <property type="nucleotide sequence ID" value="XM_008102221.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZV4"/>
    <dbReference type="STRING" id="645133.E3QZV4"/>
    <dbReference type="GeneID" id="24416924"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11560"/>
    <dbReference type="eggNOG" id="KOG4125">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006285_4_0_1"/>
    <dbReference type="OrthoDB" id="200349at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004555">
        <property type="term" value="F:alpha,alpha-trehalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005993">
        <property type="term" value="P:trehalose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.40">
        <property type="entry name" value="Glycoside hydrolase, family 65, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037018">
        <property type="entry name" value="GH65_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005195">
        <property type="entry name" value="Glyco_hydro_65_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005196">
        <property type="entry name" value="Glyco_hydro_65_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11051">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11051:SF8">
        <property type="entry name" value="PROTEIN-GLUCOSYLGALACTOSYLHYDROXYLYSINE GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03632">
        <property type="entry name" value="Glyco_hydro_65m"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03636">
        <property type="entry name" value="Glyco_hydro_65N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180980" description="alpha,alpha-trehalase" evidence="4">
        <location>
            <begin position="23"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 65 N-terminal" evidence="6">
        <location>
            <begin position="63"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 65 central catalytic" evidence="5">
        <location>
            <begin position="452"/>
            <end position="638"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ36392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1071" mass="117716" checksum="92EC5C5FF1ADA414" modified="2011-01-11" version="1">MPAMNLQALLLASVYSLGVTRGAPTSSASFDINADWVSWNDDTWTLKSTKPLPGVFTAWLPQSNGYFGLAQGSLGPFYERSRRNDSEGWPSYSNPRTTFATVTGFWGSEPSTLEPGELGESFISGVPHFTDLLVEACGSILNGDVDVSEINEFESTLSLRKNDGTDFLCSTTSKTGILTWSYVWSPATCVGDRKFLVSYESLASMVERRLAAVKLVVSSEQGLDNVHVLDLLDNQSALRTRTVKTGVNEASSQVYSAVSPDGVDHVMAYVLSSTLGDGLLGLEGKDEYSSDFFSALDFVITSDSANSSTTDPKSVFPTQRYRVQSGLQSATVYKYAAIASTEHYGSNTEAVVSSVVSSATIRGYHALREEHSAEVGKFMSADFVADFRDPVTGSLPMNGGGHVVQALQITAISSAYYLYTSLIPWSPTQDKNSSTCIACNSLGVGGLVSQTYGAPAIQGVHPKLARQFSLYRINRAEESRKNTKRHNLKEGSMLYAWTSGRYGQCYNMSAPCIMYQYHLNADIALSMTMGRNTSGDRNWYEKHGAVDVIDGVATGLSDILTRRENTGLWGIDVMADADEYYMWIADGSFTSTAVSTLLQLASEARHERGIPTETDWPDQLEHMSIPTSDDGVVLEFQGMTNDVFPKQADVILSHYPYDYKRNFSLDKYRAAMDFYAVRTDPHGPAMTWSMYAITANSLATSGCSFWTYLVKSFQPYIRGPWYQYSEQQDDEPDVLDPLTGNPINPAFPFLTGHGGLLQIFTAGFLGLRVTHRNLVINPSLPPQLRDFKPPIQYYNGAVVSFRMNRTHTFITRRDASHFDGLVPDQYGEEDMPITVGRGVDDPNARTVFLRINDTVVVQNRLYDAELSVPGNILQCHDATSSHGDLAFAATDGYGGTFWQSGTCDITAALLVDLGTSQMPRLLHAIQLDFAMRPPKYVKVSVSNSSSFELSTVLADQDIRITKPWIPDSPVAKYVGNKTTIQLTGAVWSGAFAKLEITGCWTDDGAGATVAEFGLLAANLHDFLRQYPYRPSDCLIHVQPPREVVPEHMTNLIRLTGFSNVKQLLAIFRCIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3R003</accession>
    <name>E3R003_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_11586</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697424">
        <property type="protein sequence ID" value="EFQ36441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100461.1">
        <property type="nucleotide sequence ID" value="XM_008102270.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R003"/>
    <dbReference type="STRING" id="645133.E3R003"/>
    <dbReference type="GeneID" id="24416950"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11586"/>
    <dbReference type="eggNOG" id="ENOG502SQDU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036317_0_0_1"/>
    <dbReference type="OrthoDB" id="5215637at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="137"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="284"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="88"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ36441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="305" mass="31077" checksum="F91105120C9876C0" modified="2011-01-11" version="1">MTNNHPLDPDTLVSTTAYDFRYNGVQVWQCDGEGYGVPGKFCCESAREKTRCCSTPWALFGPLIPATLGNAAAVQTYDLSATSVSAKPTSAPAADATSSPTRASKSPATPGGADVSSPTGVSGTGNNDDRSGGQGGIGLAASVGLGIGFSVGGALLIFAGVIWWLRRQRLRGGAAELDDKSIAGRHDLGGGGGNLTRPGVESPADVGGGFDNYNGRGPGTFGRRPINSMGTLGTMGTLDTMGTVGSWGTSLYGVTADPEIVTRASSDCDGSPVGVLGHYQMGGVDGKETLVTPPPQQTRFSRQGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0A7</accession>
    <name>E3R0A7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitin-like protease family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_11680</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C48 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697436">
        <property type="protein sequence ID" value="EFQ36545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100565.1">
        <property type="nucleotide sequence ID" value="XM_008102374.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0A7"/>
    <dbReference type="STRING" id="645133.E3R0A7"/>
    <dbReference type="GeneID" id="24417044"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11680"/>
    <dbReference type="eggNOG" id="ENOG502T6FE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024324_2_2_1"/>
    <dbReference type="OrthoDB" id="4807521at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019784">
        <property type="term" value="F:deNEDDylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000338">
        <property type="term" value="P:protein deneddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.395.10">
        <property type="entry name" value="Adenoviral Proteinase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044613">
        <property type="entry name" value="Nep1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003653">
        <property type="entry name" value="Peptidase_C48_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46468">
        <property type="entry name" value="SENTRIN-SPECIFIC PROTEASE 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46468:SF1">
        <property type="entry name" value="SENTRIN-SPECIFIC PROTEASE 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02902">
        <property type="entry name" value="Peptidase_C48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50600">
        <property type="entry name" value="ULP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Ubiquitin-like protease family profile" evidence="6">
        <location>
            <begin position="65"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ36545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="274" mass="30809" checksum="B16F0C58DCADB392" modified="2011-01-11" version="1">MSRYNFRSRPAKEDLPLPPTPKKRVKRSDSINHSALKQHPDVSFLSHPPTPIDVEVSELPEESGIALTNKADETIVLSSDSEPATNKDENWRENTGVWHDLQSFEPGAWLNDAAIFRVVTKLAARDKSFGVVDPLIVENFNSLSGPSWDARDFARDYFNKPKVLLIANPLRAHWVLFLWEQEKKQLYLYDSLRGGKYEAAAITSVVNLVKVAFPNEEIAAPISRECPQQPNGFDCGLHVLRNADILTSTLMPGAPEPPLDPQTMRAHYRQVFLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0D2</accession>
    <name>E3R0D2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">lytic cellulose monooxygenase (C4-dehydrogenating)</fullName>
            <ecNumber evidence="15">1.14.99.56</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">GLRG_11729</name>
    </gene>
    <organism evidence="20">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="15"/>
    <dbReference type="EMBL" id="GG697439">
        <property type="protein sequence ID" value="EFQ36570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100590.1">
        <property type="nucleotide sequence ID" value="XM_008102399.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0D2"/>
    <dbReference type="STRING" id="645133.E3R0D2"/>
    <dbReference type="GeneID" id="24417093"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11729"/>
    <dbReference type="eggNOG" id="ENOG502QRTW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031730_0_1_1"/>
    <dbReference type="OrthoDB" id="3238762at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF9">
        <property type="entry name" value="ENDOGLUCANASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="19" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 17" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179030" description="lytic cellulose monooxygenase (C4-dehydrogenating)" evidence="17">
        <location>
            <begin position="20"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="18">
        <location>
            <begin position="20"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="274"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="274"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="16">
        <location>
            <begin position="289"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EFQ36570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="301" mass="30773" checksum="976E3A332CC0B358" modified="2011-01-11" version="1">MKSIAALALTASMANMVAGHAIFQQLWVNGKDEADSCVRMPASNSPIQDPTSDDMRCNANAAKAASTCAVKAGDVVTVEMHQHNDRDCTKEAIGGAHHGPVMVYMSSVADAAAADGSEPFFKIFESGYFANNNTWGNDLINEGCGKQNVVIPADIAPGDYLLRAETVALHAAGSVDGAQYYMSCYQLKVEGSGSAKPTGVTFPGAYKATDPGLLINIYNKITNYVVPGPAVYKSGSGSGSGSAPVASAPAATSAAAATPTTLATKTATAAATTSAAAAAPTGDADAGCKRRARKARRSAHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3R135</accession>
    <name>E3R135_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_11970</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697585">
        <property type="protein sequence ID" value="EFQ36823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100843.1">
        <property type="nucleotide sequence ID" value="XM_008102652.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R135"/>
    <dbReference type="STRING" id="645133.E3R135"/>
    <dbReference type="GeneID" id="24417333"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11970"/>
    <dbReference type="eggNOG" id="KOG0158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_11_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11058">
        <property type="entry name" value="CYP60B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF210">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ASQL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="458"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ36823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="518" mass="58607" checksum="E531686E880895FD" modified="2011-01-11" version="1">MLILPFIAVKGGYNNALNVVATFLVLLVASIFIILVYRLWFHPLAKIPGPKHLAACDIFCQWRTSIRLDMATYAVDLHRKYGPIVRIGPNRLMVEGHIAWPQIWGIRSSGNSEFGKVPGYTFPNDHNALVGASWENHRRQRRHMSPAFSIAALHEQEHIINQYIDKTVNKLTELAKAGTTVDIVDWINYTTFDTIGDLCFADGFNSLDGDTSYVHNFFRGLKGSSYRRFLWHYPLLKWPMIFILGSKEFAAGQEAGINNLRLGQLKAKARIALGAEPKDGRRDITTYLLRKGKNGERILNDAEIQSLCSILVVAGSETTGTALVGIVYLLCRYPDKMDALTKEICAAFTNKDQITITNAGRLEYLNAVIEEALRMYPPAATITPRVSPGAKVEGHWLPRGTLIHFYAQGTNRNQHNFTDPDSFQPERWLSPNHPRYDPRFAHDRKEVVKPFSFGVRDCPGKNLAYADMRVIMSRLLYHFELELLPGQEDWINGQRGSLVMFKPGVNVRLKVRPEVSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q301</accession>
    <name>E3Q301_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_00124</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ24980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089000.1">
        <property type="nucleotide sequence ID" value="XM_008090809.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q301"/>
    <dbReference type="GeneID" id="24405489"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00124"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_11_5_1"/>
    <dbReference type="OrthoDB" id="4540492at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000078">
        <property type="entry name" value="MFS maltose transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF33">
        <property type="entry name" value="SUGAR PERMEASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G12040)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="123"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="213"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="343"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="368"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="396"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="436"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="474"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="44"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ24980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="523" mass="58434" checksum="9ED891C21F66C9C0" modified="2011-01-11" version="1">MSSSQHSQSLDTIASDPEARAARDYEEQHSYTQTISKFRPAIKWSIFFAITIVGEGYDLALMGNFFSMPQFQNLFGHSPGRSAAKEIPVFWQSMILTSSQLGQVSAMYFAGLSMDRFGYRRTMMFSLGTVIVFLFVTFYATAALATRDHRAGLGMIVGGSYLLACVLAYVSDISPLKLRPVLMTFVSMCWILGQLLSTVAIKSVTTIKDNDILAYRIAVAFQWVWPLPILICVFFAPESPWWLMRQSRPDLARSSLVRLNPDPAYPVDGQVKVLELTDQQEKCDQNDFEITYLECFRGVNLRRTMIVVTTNITQQLCGSSLMFYSAKLYQKAGMSSSKSYDFTLIQCAIGIICIVTSWPLMKYIGRRTIWLWGLGAAVILMAGVGVLGCFHDAHAAITWAIVILLVVFTGVYNLSIGPLTNAINPEISSTRQKAKTLVIGRVASLVAGQFNMWLLPIMLEDAPNGWGLGPRTALVYSGINVIFWVWAYLFLPEICGRPQAAIDELFKRRISARKFSQVEVETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3N2</accession>
    <name>E3Q3N2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_00778</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089654.1">
        <property type="nucleotide sequence ID" value="XM_008091463.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3N2"/>
    <dbReference type="GeneID" id="24406143"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00778"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_27_4_1"/>
    <dbReference type="OrthoDB" id="2428527at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17476">
        <property type="entry name" value="MFS_Amf1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718:SF1">
        <property type="entry name" value="LOW AFFINITY AMMONIUM TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="280"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="311"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="350"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="379"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="415"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="440"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="478"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="520"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="81"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ25634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="564" mass="60113" checksum="E6FEB0C62A95DF03" modified="2011-01-11" version="1">MTSPSLSERQTGRTSVHTLSEDRTATATPDVNPPKDEKPISSNDDASSSVYGDNDGGNLTPQQSNAPSVWLAETMSFPREVMFIIICCMAQFCTQAAFIDSLFLLHVIGSSFDVDEPARLSWLVAGYSLTIGTFILFSGRLGDAFGYKRMLIIGFAWFSLWSLVAGLSVYSNFTLAVVSRVLQGIGPAICLPNALALFGAAYPPGHRKAMVFSFFGAVAPMGGVVGGAFASVLSLAWWPWALWALSVWLAILAVAGWFIIPEPPTKLPAPDGFKAMIVELDIPGAATGVVSLVLFNFAWNMAPVAGWDTAVVLVPLILGLVLFGAFALIEFKYAPMPLLPFDVVNADVGFVLAAVVCGWATFGVWTLYLVQILQEIRSLPPLLTCAWFAPVVVTGGLAAVITGKLLGPLQVRPPVVMTMALVAFTVGVTLTATAPADQVYWAQIFVSMLVMPFGMDMSFPAATLILSNAVKKEHQGIGASLVNTVVNYGIALGVGFAGTVEVHVNNGGRTKEDQFKGFRGALFMGVGLAGLGLGVALTFLTREWRHRSDGSRNEEKAAEAQTET</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q439</accession>
    <name>E3Q439_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00495</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089371.1">
        <property type="nucleotide sequence ID" value="XM_008091180.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q439"/>
    <dbReference type="STRING" id="645133.E3Q439"/>
    <dbReference type="GeneID" id="24405860"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00495"/>
    <dbReference type="eggNOG" id="ENOG502RR65">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_685131_0_0_1"/>
    <dbReference type="OrthoDB" id="4841985at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="11"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="369"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="393"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="402" mass="43740" checksum="26A3CD403E3FC725" modified="2011-01-11" version="1">MASHHDAIDCSFDQGSSDDINPPPDKSTASEEISMATDTHTTHAEPIYPAGDLFVNLLSHENSAIAGFQLSSKVCSVASKTIATLIDTTCGTQDGRKVARLYDCVNLEVDAFRCIFSVLHYTNTNTYRHLPAKDLLQVAKVSAILDCGKALAPWICLWCDSIRQEIAGHDQPKTEELGMLLSSAITFKAEEEVAKLVAFASHHLPMNFLEMWARSQDLKDLHMNKSLNGLHLNVAKLFACTFELIHSIDGVLSSRSQVYTTGRKLCPSCGRRHPSTAKKCHPCHEIILWSELCTKQHRIGDYLRILTDKRLWPLNVLFKDDTSISQIVQRVTSMSLNISHACGGGTKCPLLVHINSLLPKVKHAVDGAVPGVEQGGKGKVQGDCGGDNGGDAAGSSNNNVAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q482</accession>
    <name>E3Q482_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Fungal specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_00538</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089414.1">
        <property type="nucleotide sequence ID" value="XM_008091223.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q482"/>
    <dbReference type="STRING" id="645133.E3Q482"/>
    <dbReference type="GeneID" id="24405903"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00538"/>
    <dbReference type="eggNOG" id="ENOG502QZJZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023798_0_0_1"/>
    <dbReference type="OrthoDB" id="4116913at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF37">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="7">
        <location>
            <begin position="264"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="21"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="623"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="23"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="58"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="630"/>
            <end position="639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ25394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="699" mass="77823" checksum="9A028D4A11B6FB0C" modified="2011-01-11" version="1">MERELYEDVVSRLAQMEKLVEELQTSKPEQEASATVSPRPSATPSSVQQSPLPRRKASSTSPSSGNPDSCPSPPSATSSIKSRPYYIGAADDTSVIAAGASSLLSTQGLAQIELLIGDARFTNALLSLRTKVVDLHRKPFLSLADLNHPLPPDHVIIDYVNEFLATWNVSIRLFQDHELRDALRSHTQGQPPDDPGWLMALNAIIAHVIRNRNCMRNKEEYQKYIHNALGMVPNIILRTPTPMTIGALLLTVKYFNFTSENHISMSLMGLTVQLLMMAGYHRLENYPSHPDLQIDPVNRLHRRRLFWRAYIIDHDLMLRMGKPPLIGDDFLLDLPEEHPADGYGMYYYPDGVTLNFFRQQVRLAQIQGHIAAALYHRIDAPPAELEAEIRRLDAELQEWRESIPPMIRAENAEALLDGDYYRMLGLTVLHFTYFQLIVAIHSAAFRLPSLGDQEGTETIDIGPSLALCVSASRASISLLNYHQIEHVFTPYLLYQVAWSVDILFVNIIQNRTNPRAHRDLELIRNVIGFFEKYDPLHQSVIAYHTIKVIADVAASVLANTPTLPPHMLPAPLGPSPIPEQPQQAAPLTAGIPVDAFSSPMGGAGLVGSGGINSGTTDMLRSMTTLSMSGTPPPPPPPPQQQQQQGFMGIVGGPTQPDETQFFPGFVNMAADWRLPMDFQPELWQYDSVLNNQFPNQSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q498</accession>
    <name>E3Q498_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_00554</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL20 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089430.1">
        <property type="nucleotide sequence ID" value="XM_008091239.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q498"/>
    <dbReference type="STRING" id="645133.E3Q498"/>
    <dbReference type="GeneID" id="24405919"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00554"/>
    <dbReference type="eggNOG" id="KOG0829">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080773_1_1_1"/>
    <dbReference type="OrthoDB" id="1294322at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.10:FF:000001">
        <property type="entry name" value="60S ribosomal protein L18a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L18a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00273">
        <property type="entry name" value="Ribosomal_eL20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028877">
        <property type="entry name" value="Ribosomal_eL20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023573">
        <property type="entry name" value="Ribosomal_eL20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021138">
        <property type="entry name" value="Ribosomal_eL20_eukaryotes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10052">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L18A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01775">
        <property type="entry name" value="Ribosomal_L18A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002190">
        <property type="entry name" value="Ribosomal_L18a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160374">
        <property type="entry name" value="RplX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein eL20" evidence="5">
        <location>
            <begin position="5"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR002190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ25410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="174" mass="20379" checksum="9EB16CB60B24AE92" modified="2011-01-11" version="1">MGRLTEYEVIGRHLPTESNPTPALYRMTIFAPNVTVAKSRYWYFLRGLKKVKKATGEIVSVKEIHEKHPLKVKNFGIWIRYDSRSGTHNMYKEYREMSRTDAVEALYSDMAARHRARFRSIHILKVVELEKGDDVKRPYIKQLITKNLSFPLPHRVTKVNNQKIFSAKRPSTFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4G6</accession>
    <name>E3Q4G6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00622</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089498.1">
        <property type="nucleotide sequence ID" value="XM_008091307.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4G6"/>
    <dbReference type="GeneID" id="24405987"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00622"/>
    <dbReference type="eggNOG" id="ENOG502QV47">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012743_0_0_1"/>
    <dbReference type="OrthoDB" id="5541877at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039966">
        <property type="entry name" value="C553.12c"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40467">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40467:SF1">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="174"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="209"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="243"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="343"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="383"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="415"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="444"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="493"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ25478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="611" mass="69900" checksum="42D0AB5FFE728227" modified="2011-01-11" version="1">MPSFFQFTQGNESRTRLTSDASPLLGRFRAVPQQSDIPGRRRRSSTLGLLTANNRGSVHVGYGALLSASGPENHDGNGTQSDWEDLGTWERTWRKISDVWVEPKQSAVKGVVDVWWSRFGVLVLMPAALAIAWCAVPFPKYSFPGDDDDDRGDTGPGSGLKIPGHGEARVQINFWFFLFVYYGFYNVTALIWITKVFNLYSLNWWPQSLGFPVTMSLIALVSIAIPIPIYLSPETRFLTMHNTAWISWTFIVMAMPVTTAFCILLTSQRHLKLRQSLSETQRIFTSSWWTGEAEGSIPRRDNRRRPNLSSDSFDPDNTLQIAADQSRHIGGVRMRRRWLPASFVRFIWFCLALFVGLLAYVIGEAYAEIYLRTLPHNNLETIVYVYSWIITVHLLDALTGWLLGIREGERVGSYPLSWVFKLYFMLTYQTYVRALYARLRSPEQFIYLQILSSSTLIILTPLTMSRLYHRITVALNFTDQSYASYQKVCTRNVFIRFLAENVSMAAFLGGVLVLHFGPNKDVYPYFAFDTKEKSDDYDFNLTFWASSVTWACELVASVCVRALIRWIFGVDVGMEGKLDLVVWPELLPTSVAVMFHVLQNMFFSIIRLQFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4I5</accession>
    <name>E3Q4I5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BNR/Asp-box repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_01144</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ26000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090020.1">
        <property type="nucleotide sequence ID" value="XM_008091829.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4I5"/>
    <dbReference type="STRING" id="645133.E3Q4I5"/>
    <dbReference type="GeneID" id="24406509"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01144"/>
    <dbReference type="eggNOG" id="ENOG502QW46">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036301_0_0_1"/>
    <dbReference type="OrthoDB" id="2130735at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15482">
        <property type="entry name" value="Sialidase_non-viral"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036278">
        <property type="entry name" value="Sialidase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38792">
        <property type="entry name" value="BNR/ASP-BOX REPEAT DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_7G06430)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38792:SF1">
        <property type="entry name" value="BNR_ASP-BOX REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50939">
        <property type="entry name" value="Sialidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178201" description="BNR/Asp-box repeat protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="379" mass="41513" checksum="F024D5FD29CAA3C2" modified="2011-01-11" version="1">MSHLMALLAFLVQSVSIVAASSAAPSAFGFFVNNTIHEPLGNGSFFYPRYTELQDGTILATASITGHSPAFFPVFESKDGGATWDWISNVTDTQNGWGFPAQPMLTVLSEPLGAYDAGTILATGNSWSDNGTRIDLYASADRARSWEFVSRVAEGGPPNTTNGYTPVWEPYLLEYNKSLICYYSDQRDPKHGQKLSYQVSTDLKAWGPVFDSVAYDEYVARPGMPVVIWVPPIAKWMIVYEYVGGYASDGSKYPVYYRLADSPLEFQTASGIPIVTDTKKIPNASPYVAWSPIGGPNGTIIVSDADNSQVFTNQFGGDMNEWEEHATTAPMAYSRPVQILRQYPDHLVIYGAGTYDSFSSNMLTPLTATAINLTEILIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4P0</accession>
    <name>E3Q4P0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_01199</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ26055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090075.1">
        <property type="nucleotide sequence ID" value="XM_008091884.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4P0"/>
    <dbReference type="GeneID" id="24406564"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01199"/>
    <dbReference type="HOGENOM" id="CLU_1959405_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ26055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="128" mass="14744" checksum="83126E895859D392" modified="2011-01-11" version="1">MSLGSTCQCPCDTCLGGSLGLCDATRPEFVCRCGFRNIVTKQWNEHGRVRRQDQCRCGEILCEKRARDHVKGCRLGGKKYVCLRPRTGDHVESHRLEFTDRKDFLAHFNDECKGRRAGRPREEKTRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4Q4</accession>
    <name>E3Q4Q4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_01213</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ26069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090089.1">
        <property type="nucleotide sequence ID" value="XM_008091898.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4Q4"/>
    <dbReference type="STRING" id="645133.E3Q4Q4"/>
    <dbReference type="GeneID" id="24406578"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01213"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_3_1"/>
    <dbReference type="OrthoDB" id="417891at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000173">
        <property type="entry name" value="3-oxoacyl-[acyl-carrier protein] reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF127">
        <property type="entry name" value="3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ26069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="279" mass="29154" checksum="52AB50664B7F6BE2" modified="2011-01-11" version="1">MVQHSIRNTDNNPQGRLALVTGASGGIGSSVAHALAAEGCDVALHYSSNQGKAEALAEKLRSQYPSQLFLPFQADLASRESTRSLVPGILANGEISRKHKAISILVANAGLGRRIRDPADIGEEDWDEMMEVNSRSQFVVTKGCLPGMRAQGWGRVVLVGSIASRGGGINGCHYAATKGALCSMGLNLATLLAPEGVTVNIVLPAMIGATGMIATPKSTTWDSRDDLEALRTTDPGLAIAASVPVHRLGAPEEVSNVVTMFVKTGYLTGQELVLAGGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4X3</accession>
    <name>E3Q4X3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADH-cytochrome b-5 reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_01282</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ26138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090158.1">
        <property type="nucleotide sequence ID" value="XM_008091967.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4X3"/>
    <dbReference type="STRING" id="645133.E3Q4X3"/>
    <dbReference type="GeneID" id="24406647"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01282"/>
    <dbReference type="eggNOG" id="KOG0534">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003827_7_1_1"/>
    <dbReference type="OrthoDB" id="436496at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00322">
        <property type="entry name" value="FNR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052128">
        <property type="entry name" value="Oxidoreductase_NAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46505">
        <property type="entry name" value="OXIDOREDUCTASE NAD-BINDING DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46505:SF1">
        <property type="entry name" value="OXIDOREDUCTASE NAD-BINDING DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="3">
        <location>
            <begin position="21"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ26138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="304" mass="33773" checksum="54A5CCD7619DB273" modified="2011-01-11" version="1">MRPTSSKYSHIERTAAEPRDPSLHTVVLNRVEEVNESIRLFRLGIFEGSSIKFLPGQWLDIFVPGVLNPGGFTITSPPSIAMLPSSAYLELAVQYSPSNPPAIWLWGNPVDGSDAVHSHNSENEPVQLRVRVGGSFVWPPQSIDLTTLRRVVFVAGGLGINPLMSILSHLAERGGSRYDVQFLYSTKTPAEGLEPGKILFLERLSATYGRKKVRGQLKLFLTHIQGTSGPSETVLLCNEVEVPFKRRRMTLEDIAEALGPEEEHKWAVVYVCGVPTMTDEFLGKITSPHGLGLGREQVLYEKWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4Z5</accession>
    <name>E3Q4Z5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_01304</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ26160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090180.1">
        <property type="nucleotide sequence ID" value="XM_008091989.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4Z5"/>
    <dbReference type="STRING" id="645133.E3Q4Z5"/>
    <dbReference type="GeneID" id="24406669"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01304"/>
    <dbReference type="eggNOG" id="ENOG502S34X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030082_0_0_1"/>
    <dbReference type="OrthoDB" id="422106at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000340">
        <property type="term" value="F:RNA 7-methylguanosine cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019416">
        <property type="entry name" value="NCBP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16291">
        <property type="entry name" value="NUCLEAR CAP-BINDING PROTEIN SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16291:SF0">
        <property type="entry name" value="NUCLEAR CAP-BINDING PROTEIN SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10309">
        <property type="entry name" value="NCBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="50"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="164"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="392"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="19"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="164"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="238"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="262"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="284"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ26160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="419" mass="46727" checksum="7B421B562723C4B9" modified="2011-01-11" version="1">MDWDIDMDDIAEGFAPPNVTISDSTNTRESGTAPSTTTERDPESPTLVPNKVHIRGLETLTTDDIKTYVKDHYGPMNRVEWIDDESANLVFGTESSAQDALKALSAVEIVDVTQLPINETIPAKAMASKPDVNLQVRFAMISDKKAPGAAQRSRFYLFHPEFDPEERMRGDGSRNRYRDRSGDDHYRRNGRGRDRRDRESSVEVFHASMYDDEDTLADRDSRAARQRRRSHSRGSSSRGDRSYTSRNQEKELFPGRGPAGGRGERNRSASPKRDADGDAAMDIEAARILRPSNRERASGIKERLAMDNKAKELFPTKGSSAGQTHMDRVMDGADETTRLMQRNLSVSNEGGSTNDLFDIRGRARKQGVDTGFTIKGAAGASVKELFPDRFGSGNTGKELFTNKLEGRGRRRQKAEDLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5F4</accession>
    <name>E3Q5F4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_01065</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089941.1">
        <property type="nucleotide sequence ID" value="XM_008091750.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5F4"/>
    <dbReference type="STRING" id="645133.E3Q5F4"/>
    <dbReference type="GeneID" id="24406430"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01065"/>
    <dbReference type="eggNOG" id="ENOG502QTB6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1288812_0_0_1"/>
    <dbReference type="OrthoDB" id="2956246at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="218" mass="23135" checksum="5CD4B3D0C23A9DFB" modified="2011-01-11" version="1">MPLPVLSKQPIPGVTLSVASLIALADLHTIANRAALTGTSSWADALVLAPGLHYQHAAECVAGNSGNGTSSEASSSGGDDGNGGRKSTRPAGVYGTQEHPGGRTTDFRVTNPGMLLFLSQLRGREERAQQHERKTRRKRTDSRVEALGTDSDDSGGEEKVIDVDISPSGHRHHRHGEASAHHPRWNERGSHLLYLTTPALTLATPTVMILLADCCAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5I1</accession>
    <name>E3Q5I1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">endo-polygalacturonase</fullName>
            <ecNumber evidence="3">3.2.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Pectinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">GLRG_01092</name>
    </gene>
    <organism evidence="19">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>(1,4-alpha-D-galacturonosyl)n+m + H2O = (1,4-alpha-D-galacturonosyl)n + (1,4-alpha-D-galacturonosyl)m.</text>
            <dbReference type="EC" id="3.2.1.15"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the glycosyl hydrolase 28 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.15" evidence="3"/>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089968.1">
        <property type="nucleotide sequence ID" value="XM_008091777.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5I1"/>
    <dbReference type="STRING" id="645133.E3Q5I1"/>
    <dbReference type="GeneID" id="24406457"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01092"/>
    <dbReference type="eggNOG" id="ENOG502QTAW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040116_0_0_1"/>
    <dbReference type="OrthoDB" id="1546079at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004650">
        <property type="term" value="F:polygalacturonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.20.10:FF:000002">
        <property type="entry name" value="Endopolygalacturonase D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000743">
        <property type="entry name" value="Glyco_hydro_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050434">
        <property type="entry name" value="Glycosyl_hydrlase_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31884">
        <property type="entry name" value="POLYGALACTURONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31884:SF1">
        <property type="entry name" value="POLYGALACTURONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00295">
        <property type="entry name" value="Glyco_hydro_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00502">
        <property type="entry name" value="POLYGALACTURONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10 15" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 15 18" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 17" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178222" description="endo-polygalacturonase" evidence="17">
        <location>
            <begin position="17"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="42"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="101"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="active site" evidence="14">
        <location>
            <position position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00083621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU361169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EFQ25948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="476" mass="49497" checksum="792C82200E08567F" modified="2011-01-11" version="1">MKFLIMTSGLSALGAAAIFPGHLRPNMIPKLANTTIPAQNLTIPAPSSATNPPTRATDPVSEVTSAPAEVSSMPITLPDTNQGNCTCPDLGSSPPNNGTFGQPDPDGGDQQLPGGDIGAGPGPAACVITDYESVEAQKASCTDMFLKGIAVPGGRTLDLTGLQPGTRVTFAGTTTFGYKEWEGPLVSISGDGVSVVGAPGHVIDCDGDRWWDGKGVKMNGKGVEMNKKKKGKGSVKPRFFTVRISNGSVSGLNVLNTPARGFNINGASNLEVRDILFDNRDGQCGGGKNTDAFHVGESTDITIVRARVYNQDDCLSITSGARILFRDGYCRGSHGLSVGSVGGRDVNNVTDVMIRDSVLEKGVNGIRIMGEHKKQGSIAGVTFQNILFKNVKKQGIVVQQDYKTGKKPSGKPTDGVPITGVTITNITGTVAEKGTNVLILCAEGACADWAWSGIDVSGGKTSKKCKNIPDNSGASC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5Q8</accession>
    <name>E3Q5Q8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_01693</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090569.1">
        <property type="nucleotide sequence ID" value="XM_008092378.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5Q8"/>
    <dbReference type="GeneID" id="24407058"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01693"/>
    <dbReference type="HOGENOM" id="CLU_1875274_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="136" mass="14746" checksum="456878EFF4F96B25" modified="2011-01-11" version="1">MRVLLKNRSQKTSRTRNRSSPTPPACSMQGGAESRGQGRKPALQQQQQQQQQQQRASASSGVRRHDSGKRRARDANRIMEGPWAGTGRDPWDGHLAPLALAEGLGRAAANDGCRPSLHLLHMVVGDAGRRASGHVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5Y5</accession>
    <name>E3Q5Y5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Eukaryotic translation initiation factor 2 subunit gamma</fullName>
            <ecNumber evidence="2">3.6.5.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_01377</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.3" evidence="2"/>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090253.1">
        <property type="nucleotide sequence ID" value="XM_008092062.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5Y5"/>
    <dbReference type="STRING" id="645133.E3Q5Y5"/>
    <dbReference type="GeneID" id="24406742"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01377"/>
    <dbReference type="eggNOG" id="KOG0466">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027154_0_1_1"/>
    <dbReference type="OrthoDB" id="1045173at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005850">
        <property type="term" value="C:eukaryotic translation initiation factor 2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043614">
        <property type="term" value="C:multi-eIF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990856">
        <property type="term" value="F:methionyl-initiator methionine tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001731">
        <property type="term" value="P:formation of translation preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045903">
        <property type="term" value="P:positive regulation of translational fidelity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd01888">
        <property type="entry name" value="eIF2_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03688">
        <property type="entry name" value="eIF2_gamma_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15490">
        <property type="entry name" value="eIF2_gamma_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000009">
        <property type="entry name" value="Eukaryotic translation initiation factor 2 subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Eukaryotic translation initiation factor 2 subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Eukaryotic translation initiation factor 2 subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050543">
        <property type="entry name" value="eIF2G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015256">
        <property type="entry name" value="eIF2g_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044127">
        <property type="entry name" value="eIF2g_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044128">
        <property type="entry name" value="eIF2g_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003077">
        <property type="entry name" value="PRK04000.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42854">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42854:SF3">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09173">
        <property type="entry name" value="eIF2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 12" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="11">
        <location>
            <begin position="82"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00074422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ26233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="521" mass="56461" checksum="F0E2F39BFC593930" modified="2011-01-11" version="1">MSADSVSNHEDMDPVSNSGEFAEEEVTSEPLASNTKEVHFSDTAKDAAKETVERPFLPEQTDPEHIDFEKHDALNPEVIARQATINIGTIGHVAHGKSTVVKAISGVQTVRFKNELIRNITIKLGYANAKIYKCDSPECPRPGCYKSYKSEKEVDPPCERDGCSGTYRLIRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLDNLIILQNKVDLMRQDAAGKHKDTITKFVRGTVAANSPIIPVSAQLKINIDAVLDSIVNTIPVPTRNLTKDPLMIVIRSFDVNKPGAEIEDIKGGVAGGSILHGVLKLGDEIEIRPGIVERDDKGNLKCTPIFSKIVSLNSEGNELKYAVPGGLIGVGTKIDPTLCRADRLVGHVLGLKGRLPDIYKEIEVNFFLLHRLLGVKTADGKQAKVAKLTKNEVLMVNIGSTSSGASVFAIKNDAAKLRLNTPACTNIGEKIALSRRIEKHWRLIGWATIVAGVTIEPSVRIEPSSSKTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q654</accession>
    <name>E3Q654_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mitochondrial intermediate peptidase</fullName>
            <ecNumber evidence="4">3.4.24.59</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Octapeptidyl aminopeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">GLRG_01446</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Cleaves proteins, imported into the mitochondrion, to their mature size. While most mitochondrial precursor proteins are processed to the mature form in one step by mitochondrial processing peptidase (MPP), the sequential cleavage by MIP of an octapeptide after initial processing by MPP is a required step for a subgroup of nuclear-encoded precursor proteins destined for the matrix or the inner membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal octapeptide as second stage of processing of some proteins imported into the mitochondrion.</text>
            <dbReference type="EC" id="3.4.24.59"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="15">Binds 1 zinc ion.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the peptidase M3 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.59" evidence="4"/>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090322.1">
        <property type="nucleotide sequence ID" value="XM_008092131.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q654"/>
    <dbReference type="STRING" id="645133.E3Q654"/>
    <dbReference type="GeneID" id="24406811"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01446"/>
    <dbReference type="eggNOG" id="KOG2090">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001805_0_0_1"/>
    <dbReference type="OrthoDB" id="17530at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006518">
        <property type="term" value="P:peptide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006627">
        <property type="term" value="P:protein processing involved in protein targeting to mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06457">
        <property type="entry name" value="M3A_MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.10">
        <property type="entry name" value="Neurolysin, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033851">
        <property type="entry name" value="M3A_MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024077">
        <property type="entry name" value="Neurolysin/TOP_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804:SF79">
        <property type="entry name" value="MITOCHONDRIAL INTERMEDIATE PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804">
        <property type="entry name" value="PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 15" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 15" id="KW-0645">Protease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="9 15" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M3A/M3B catalytic" evidence="16">
        <location>
            <begin position="283"/>
            <end position="777"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00032470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EFQ26302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="789" mass="88661" checksum="A2E5F70030F811E8" modified="2011-01-11" version="1">MFKSPSRSLWVCTRCVRQASRGQPRRWMAAVSGAAPSSITADHSPPGRNTDDAILRELFDSPDRVAKAFKAAGPSVGLFKNRYLTSPNGFYVFARRSLEKAQKIVHRVLHASSVSEYQAIVKDLDRLSDLLCRVLDLSDFVRMTHPDPRFQQAAAGAWSMVYQYMNQLNTMTGLSDQLVKAMGQPDVVAVWSEEERTVAEILKLDFTKSAVDLPQQERDRFVDLSQQISEVGSMFVSEMSPAKREIVLPSSNFYGLYPGIARALTMRGKLRLPTTGPEAQAALRSVKDDGTRKEVYTAMRTASKQTVRLLETMLKLRSELANLAGFSSYAHLSLKDRMMAKSPGAVMQFLQALQKYNSPIVQEEMADLLKLKQTRLDASATQVHPWDKDFLMDGVRSEMRLPVRHPDHLPSFFSIGTVMQGMSRLFTRLYGIQFKPKESQPGETWHEDVRRLDVVTDTGDLIAVLYCDLFFREDKSPNPAHFTVRCSRAIAPYEVQEAAEDLHNATADMPKFERPEQAANDGMESLQQDGVLMQLPTIALVCDFPKHDAGSSAPALLSYYQVETLFHEMGHAIHSILARTKLQNVSGTRCATDFAELPSTLMEHFAADPSVLGLFARHWKTDEPLPYQMVAERIRLAKRFEGIDTENQILLSLLDQSYHAPEVASPSFDSTQVYHNLQRQYSQGGPDPPGTCWQGFFGHLHGYGSTYYSYVFDRVLAERVWRVVFRAGSDGKALDRANGERLKENLLKWGGSRDPWQCLADTLQDDRLARGDDKAMALVGSWGIKDDHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q701</accession>
    <name>E3Q701_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02459</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090659.1">
        <property type="nucleotide sequence ID" value="XM_008092468.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q701"/>
    <dbReference type="GeneID" id="24407824"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02459"/>
    <dbReference type="HOGENOM" id="CLU_2483228_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="87" mass="9993" checksum="1B6E2E74A9E9C922" modified="2011-01-11" version="1">MSRASAKRSTRSMQTSTTSTKKSAASMKIQVNDNHVNVMHLKATTNQINKDIKDLKAGANMRISARNINKQRRFRNLWAIRNHKDHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7L3</accession>
    <name>E3Q7L3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_02671</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090871.1">
        <property type="nucleotide sequence ID" value="XM_008092680.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7L3"/>
    <dbReference type="STRING" id="645133.E3Q7L3"/>
    <dbReference type="GeneID" id="24408036"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02671"/>
    <dbReference type="eggNOG" id="ENOG502SA7U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089381_1_0_1"/>
    <dbReference type="OrthoDB" id="4822at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47251">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G04180)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47251:SF1">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G04180)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0862">Zinc</keyword>
    <keyword evidence="1 2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="4">
        <location>
            <begin position="23"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="121"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="136"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ26851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="169" mass="18364" checksum="B00041F8D31C3958" modified="2011-01-11" version="1">MPPRHQTLPPAQTAAAREALQSFYCSLCSKGYSRMNDYEAHLSSYDHSHKQRLKDMKAMVRDPNAGARARKAEAKADGLVSIKLAPNEQPHQTATMGGFKKGGFKKSGFKSAFAPADALAASAPDTPKSKVGQALEADRLANARERDTAAESDTDDEGYQVYDPRHPTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7N7</accession>
    <name>E3Q7N7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cell wall protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02070</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ26899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090919.1">
        <property type="nucleotide sequence ID" value="XM_008092728.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7N7"/>
    <dbReference type="STRING" id="645133.E3Q7N7"/>
    <dbReference type="GeneID" id="24407435"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02070"/>
    <dbReference type="eggNOG" id="ENOG502T2SE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110347_1_1_1"/>
    <dbReference type="OrthoDB" id="3638982at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180196" description="Cell wall protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="168" mass="17131" checksum="8CA47AD732BC3C62" modified="2011-01-11" version="1">MKTYAVVLSLAALTVAQTTGGGATPVPPPIPAANDTPACAEAKILAGGIALNILVQQQEVNSLNAVIQALQGNPVNQQQFQTAKSNLLSFVSDGIQIRQSNQLIAPTGNAATAGLAVVANAQLGELEKASGLTGNPQTDNAVTQSLMSDFNGGIKKNIENQQNAIQGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7Q9</accession>
    <name>E3Q7Q9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_02092</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ26921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090941.1">
        <property type="nucleotide sequence ID" value="XM_008092750.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7Q9"/>
    <dbReference type="STRING" id="645133.E3Q7Q9"/>
    <dbReference type="GeneID" id="24407457"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02092"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_11_3_1"/>
    <dbReference type="OrthoDB" id="3936150at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015606">
        <property type="term" value="F:spermidine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000297">
        <property type="term" value="F:spermine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140115">
        <property type="term" value="P:export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042908">
        <property type="term" value="P:xenobiotic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF182">
        <property type="entry name" value="POLYAMINE TRANSPORTER, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="322"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="361"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="65"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ26921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="384" mass="41865" checksum="7599F2A7399A90E9" modified="2011-01-11" version="1">MSAFNSNPLPQQQQDAGVTATDVEKQVESDTTSSGDDSQQPQIAWDDPREMRNPRNWSTAMRILHTAIPCFLAFEITFATSITVPASTHIMQEFSVSRTRSILPLTLYTLGLGFGPLFMAPFSEVFGRKPLYAVSCTFLLAFLGGSSAATTFSALLACRFLAGTLGSAGIAVGAGTIADVWELGKGAAASLLFILGPFLGPTLGPLAGAYVLEDRDGDWRWTQYVLLMVGAPIWVGILLMRETSKSWILRKENGEPTVTLSRLGGLAKTAVMRPTEMLFTEIIVSSLALYTAYAYAMIFSYFASSSYVLQRYYGFNLRQVGLSFISVVIGYILAAFVYRFLDARCRMPAVRAGTATPEQRLYVALVGSVLIPVGLFCLYHNTHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7Z7</accession>
    <name>E3Q7Z7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Patatin-like phospholipase domain-containing protein</fullName>
            <ecNumber evidence="7">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_02180</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Lipid hydrolase.</text>
    </comment>
    <comment type="function">
        <text evidence="1">Probable lipid hydrolase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Membrane</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the PLPL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="7"/>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091029.1">
        <property type="nucleotide sequence ID" value="XM_008092838.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7Z7"/>
    <dbReference type="STRING" id="645133.E3Q7Z7"/>
    <dbReference type="GeneID" id="24407545"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02180"/>
    <dbReference type="eggNOG" id="KOG2214">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009031_2_0_1"/>
    <dbReference type="OrthoDB" id="15478at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006641">
        <property type="term" value="P:triglyceride metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07232">
        <property type="entry name" value="Pat_PLPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050301">
        <property type="entry name" value="NTE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021771">
        <property type="entry name" value="Triacylglycerol_lipase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226">
        <property type="entry name" value="NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226:SF66">
        <property type="entry name" value="TRIACYLGLYCEROL LIPASE PTL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11815">
        <property type="entry name" value="DUF3336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6 7" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="5 6 7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="PNPLA" evidence="9">
        <location>
            <begin position="383"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="748"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="6">
        <location>
            <begin position="414"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="62"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="750"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="782"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="416"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ27009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="795" mass="90208" checksum="1B69A5D34DF85835" modified="2011-01-11" version="1">MAEDQSRVSFAPSSGSNTDIYGFPPETFTTEDLPDFDTKFLDDADLAAFVHALQAPDPLQTPDDTTSLRSPGLRSTSSLDVTKRGSVYEYRDDPQAVAAAAAAAAGEVTAPGPALGRSSGNGGAYNGSTTQHNMFITAQNDWAPVNQKILKRGSRRRRNRAKGAAETLLGTRTKDETREGIFYALLKWPMLFFVAAWLSGLAMTYLYTRLYIWVYEHFVTWRGTRERLRRSMRRTNNYRDWVVAAKELDSYLDRQRWKEENDFAYYDSKTVKRVWEQMRKCRQRAEAQENGETDDQGQNKPQGRPAVEELHALLSACVKSNFVGVENPRLYSQTYYGTKNLVQNFVDEVERSIKFVLNTKQLSMEEKRSIFKGMHTNYGRTALCLSGGASFAYYHFGVVKALLEADLLPDVITGTSGGALVAALVATRTNDELKKLLVPALAHRITACRETFWTWIPRWWKTGARFDSVDWAKQCSWWTRGSMTFREAYERTGRILNVSCVPADPHSPTILCNYLTSPDCVIWSAVLASAAVPGILNPVVLMMKQRDGTLVPYSFGHKWKDGSLRTDIPIKALNLHFNVNFTIVSQVNPHINLFFFSSRGSVGHPVTHRKGKGWRGGYVMSAVEHYLKLDMTKWLKFIRHAELLPRPLGQDWSQLFLQTFSGTITIWPKTVPSDFYHILSDPDPPRLARMIHEGQQRGYPILKFVGNRLKIERLIEQGRRATRPWARRGSIETILSEDDLRSLLISGNTDIEDETTDAEGETMLENEENEEAIVDEEEEYKDEGRGRHENGDRTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q835</accession>
    <name>E3Q835_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">2OG-Fe(II) oxygenase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_02218</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091067.1">
        <property type="nucleotide sequence ID" value="XM_008092876.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q835"/>
    <dbReference type="STRING" id="645133.E3Q835"/>
    <dbReference type="GeneID" id="24407583"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02218"/>
    <dbReference type="eggNOG" id="KOG0143">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010119_6_1_1"/>
    <dbReference type="OrthoDB" id="288590at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044283">
        <property type="term" value="P:small molecule biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.330:FF:000030">
        <property type="entry name" value="Thymine dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10209:SF804">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10209">
        <property type="entry name" value="OXIDOREDUCTASE, 2OG-FE II OXYGENASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00682">
        <property type="entry name" value="IPNSYNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="6">
        <location>
            <begin position="187"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ27047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="338" mass="37482" checksum="C4716296706243F1" modified="2011-01-11" version="1">MAATAVDKEGLFIPLINFSDFLNGDDDTRTATAKQILNGFQNAGFIYLQNVPISDELRAATFAKSADFFAQDDEAKLALGWTTPEANRGYSAPGREKVSNLKTNAEIEKVRAGNPDLKESYEIGREGEPDHPNQWPTEKEGTRVAGFKSQMLEFHNRCKELHVEVMRAIAVGMGLDEHFFDTFTDAGDNTLRLLHYPSVDPNIFKVNPGQVRAGEHSDYGSITLLFQDDRGGLQVKSPNGQFVDATPIPGTVVVNAGDLLARWSNDTIKSTIHRVVEPPRKPEDGTKYPPRYSIAYFCNPNFKSHIEAIPGTYATEAEKKYEGINSGTYLVQRLTATY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q905</accession>
    <name>E3Q905_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Frequency clock protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02014</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091539.1">
        <property type="nucleotide sequence ID" value="XM_008093348.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q905"/>
    <dbReference type="STRING" id="645133.E3Q905"/>
    <dbReference type="GeneID" id="24407379"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02014"/>
    <dbReference type="eggNOG" id="ENOG502RXI4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007103_1_0_1"/>
    <dbReference type="OrthoDB" id="2536795at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007623">
        <property type="term" value="P:circadian rhythm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018554">
        <property type="entry name" value="FRQ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09421">
        <property type="entry name" value="FRQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="352"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="382"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="507"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="597"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="655"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="834"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="951"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="233"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="270"/>
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    </feature>
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            <begin position="281"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="354"/>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="382"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="423"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="534"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="597"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="663"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="840"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="878"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="900"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="923"/>
            <end position="936"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="973" mass="104034" checksum="C3C93471063BE9ED" modified="2011-01-11" version="1">MSDAQHPSNGTQPPTSPKGHPLPRRSSPENSITLRHHRLAHEASAKALSKRAAAAAETSSGSSPHRHSSGESHNTGPSDPKKWFEQSNENPAVLYSNAIDVDPPFFQKESDSSHEDNTQPTSYPTHLKRSIGGTLKPSATHSSSADDYRSVIDDLTVEIKRLKDELKRYKQRGPEMMKQDRLFEIKVHGLPKRKKRELEITLRDFASGLESSTPSAEASSGRNKGSHKARLESGSGSASKHASSTSGSHSRPVDSAYASMSTGANSSGTSLARPSASSRAKSSEQKVENYLKDIPEGLYPRHMVMTDKDKKKLIVRRLEQIFTGRISGRSVSRHQPKSSGNIASYAPIMVEPATGNTTTTHGPSNVPTGFFEPSREARILGSEEGKNRAKDNGSTSNGDQLDTGGNSAVAGTSPPDPPFPEQRPTRPLDLDPDRKQNPSANMDYIRHLGLAPPHLTGLATYEDVSPDADGWVYLNLLCNMAQLHMLNVAPDYIRSAVSEKSTKFQLSSDGRKIRWRGGTDGTKFSSDSSGETSHTSRSEESDAANDEHTKKRKRRQGPKSGLYPSSAGPNSSDQSKFDPQMSSADSFHYKPLFVHQSSSAEQTSLDDSNSSGAGEDSNNGASRWGNSGSGSAPRKRRRLDGAIIYYSGAPFCMDLSGDPGDLSPSSYLTSTGQEQQSPSSQNSRPGPQRTQSGSALAYRPLTDDKTASSVAVATEMGSDDSDMDIEAEFPWSDRPQDLVANSLDACGLGGVIPDDHFRVIATTRRPKISATSSSSSGLERNDVANLVDRITSPLGSTSRVGLLKPKSKSHLPVTIEYTSRSIEKLNPAPLPPPGMYFSFDSDSSGTSVEDVSEPEDEPMALVGSFGVQGHPSTIENQYPDDVDMSSGDEEDVEPDDGDEPVVKVDDHSSDGFAIPNLPRAAHRASSSSAVAAAGTARSRSKSFSAELLVGTGSSVATAGGAESGYSSSLEESG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9G2</accession>
    <name>E3Q9G2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fungal specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_01836</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091361.1">
        <property type="nucleotide sequence ID" value="XM_008093170.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9G2"/>
    <dbReference type="STRING" id="645133.E3Q9G2"/>
    <dbReference type="GeneID" id="24407201"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01836"/>
    <dbReference type="eggNOG" id="ENOG502SM8G">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017443_2_0_1"/>
    <dbReference type="OrthoDB" id="3266505at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF9">
        <property type="entry name" value="MISCELLANEOUS ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="3">
        <location>
            <begin position="246"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="82"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="543"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="96"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="615"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="647"/>
            <end position="670"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ27341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="738" mass="81517" checksum="94B2A37A417D31F4" modified="2011-01-11" version="1">MDAAESPNATSESGTLSPAHFAHHSRKRKHSGSTDDRPTREYGLMRDTGRHDTSRFVGSGSGIHFIRSVYVRLARKSALRTSQSNSINDLVPGEDDQLRSDASSRDGDEQNLWRAHELLQDAADPPPFEQLVDWSKSYFEAWHPTLPFLSAPDVLGLFEKVSAAGVASLGHLERSIVKAILSISLADSRQRAPFAQLVPSYLVFRTVEEAMLASQFALCQPASIQATQAALAIQLFLVSMLRLNSASRLGGLIVRMAFHLGLHRCPSRYPFFTKEVARMRRRVFWCIYCIERFLCQALGLPLDIRDDDVDVCYPSQERHGAPSDESEDGRLQLLTYHVKHARIRGLILELRNKSIHSRDDTAERASYVQAELAKWSNEIHDAVEDEVAYEESASPPPISSGHRLFLLVLKYESMISLNRPMMTSDPSSPAYSTGLQNCIFAAKSIFIALKKYQSQNGIPTEPTSPCLLEPMLQPSFTWAVWISAFILIYAAFERQLPLGSALKHVESGKQILRHIASRDTSWPEYCLSVIDELTAAVRELSIPPNPLRQHPSTGTPMSSGHLHHDAGRSAPPSSSSDRPRNSHPRARFSPSVAVSTGRPDKQGLVSHDSTRWPRQIQSDGASTANGKSSRRPAQTSPTPDTPANPRGTASTPGGQSWFQSAARQDSSSFDAQPFSISSAAASFPSPSIDVTETIPGEGQESMVWYDQLFANSFAALDYPFLAAAQFDSSVDPMWSYLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9I4</accession>
    <name>E3Q9I4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_01858</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091383.1">
        <property type="nucleotide sequence ID" value="XM_008093192.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9I4"/>
    <dbReference type="STRING" id="645133.E3Q9I4"/>
    <dbReference type="GeneID" id="24407223"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01858"/>
    <dbReference type="eggNOG" id="ENOG502SJ6K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1224674_0_0_1"/>
    <dbReference type="OrthoDB" id="3903189at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="109"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="9"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="149"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="165"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ27363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="226" mass="25265" checksum="35A9CF4381480B9C" modified="2011-01-11" version="1">MLSMFLGLSYLAVIVTLYGGWCRPFSDYLVLQPQNEQCLTWRDYNILQLSMNLSTDLVLLLIPVTLISRMNMKIGKKLLLIALFSMGIFVMLSAILLKVAVFSNMFDPVWLIWCIREVSTAMLVGNLVLCMPIFKIWWKFFSSRIGSLRKGSTESGNSDMKGVTQDPQSAGFKTTTTMSESGYSRWNSIAGLPQSPTDYGPMFGADLEDHSGARTTNRKLSISQGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAF7</accession>
    <name>E3QAF7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Choline-sulfatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_02989</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091865.1">
        <property type="nucleotide sequence ID" value="XM_008093674.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAF7"/>
    <dbReference type="STRING" id="645133.E3QAF7"/>
    <dbReference type="GeneID" id="24408354"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02989"/>
    <dbReference type="eggNOG" id="KOG3731">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006332_9_1_1"/>
    <dbReference type="OrthoDB" id="96314at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16032">
        <property type="entry name" value="choline-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.720.10:FF:000032">
        <property type="entry name" value="Choline sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017785">
        <property type="entry name" value="Choline-sulfatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025863">
        <property type="entry name" value="Choline_sulf_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03417">
        <property type="entry name" value="chol_sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45953">
        <property type="entry name" value="IDURONATE 2-SULFATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45953:SF1">
        <property type="entry name" value="IDURONATE 2-SULFATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12411">
        <property type="entry name" value="Choline_sulf_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00523">
        <property type="entry name" value="SULFATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00149">
        <property type="entry name" value="SULFATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sulfatase N-terminal" evidence="5">
        <location>
            <begin position="33"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="Choline sulfatase enzyme C-terminal" evidence="6">
        <location>
            <begin position="485"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ27845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="565" mass="63925" checksum="25EFEBC0BD164D0A" modified="2011-01-11" version="1">MAPDLNSLPSSPVAQPAHSKPANGNGATSAKQPNILFIMADQLAAPQLKMYNPESQIKTPNLDALAAESVQFDSAYCPSPLCAPSRMSLITGLLPMKIGAYDNASQISSEVPTYAHYLRLKGYHTALAGKMHFIGDQLHGYETRLTSDIYPGDFGWVVNWDEPDTRLEWYHNSSSILQAGPCVRSNQLDYDEEVMYRSTQFLYDHVREGPEKRPFALTVSLTHPHDPYTIEDKYWDLYEDVDIALPKVRIPKEEQDPHSKRLMKVCDLWDYDFTDEQIKRARRAYYGSVSYVDDCVGRLLSVLKKCGLDDNTIIVFSGDHGDMLGERGLWYKMSYFESSVRVPLFVRHPHEFEPHRVTKNVSTLDILPTLCDLVGTKPAPGLPMDGTSLLPHLQGKTGHDKVYAEYTGEGTISPLVMIREGPWKFTHCPVDGTQLFNLEHDPLELVNLASQKAISGKLLEEEAKAKLEEYTAETKAKWDFDAITEQVLQSQRKRRLVWGALTQGTFTSWDYDPVDDGRMKYIRSQIPLDDLERRARYPPVDKYGREVDRATNGQRVYSQAGSHGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBN4</accession>
    <name>E3QBN4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_03517</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092393.1">
        <property type="nucleotide sequence ID" value="XM_008094202.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBN4"/>
    <dbReference type="STRING" id="645133.E3QBN4"/>
    <dbReference type="GeneID" id="24408882"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03517"/>
    <dbReference type="eggNOG" id="ENOG502SNA7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046577_0_0_1"/>
    <dbReference type="OrthoDB" id="5365129at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178346" evidence="1">
        <location>
            <begin position="23"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ28373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="373" mass="41798" checksum="6FA10C567754643E" modified="2011-01-11" version="1">MAALGFAIDAAGLFASLSLSGAFDKPTPAEAKTNIQIILGSGERTTTAGGPRPHIALWDDGKYISYYGHRIGQYTPDKKKIKAGDQTNIVIEHTQTEPKHSQADPYYVMLSQMDDDAICISAVLVSNGKISGAFYGDTGYKCGQSWFASENRIGSDFEAPRCVWLDANHDNGINARAISFHLNDMQPNDDKLEQYYENLDTLCKSTPRFSFWGNLLPDAIPPMFKPRLKYKNGNGADEDLSKVLDDPEHPWDKGAYMAPKKVNKPKRRDVHVKRRSSNRNTGHLIISDQDTDVREICESETSYGWDIVSTKQKLFCDMEHKQLYPLCDTSVTTKCFDVDQKTLAGAPGLDTRDEEVIKMRFGRSYNTTNVWKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QC47</accession>
    <name>E3QC47_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_03579</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092455.1">
        <property type="nucleotide sequence ID" value="XM_008094264.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QC47"/>
    <dbReference type="GeneID" id="24408944"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03579"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_22_3_1"/>
    <dbReference type="OrthoDB" id="3437016at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015174">
        <property type="term" value="F:basic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046943">
        <property type="term" value="F:carboxylic acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1720.10:FF:000013">
        <property type="entry name" value="Related to multidrug resistance proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF84">
        <property type="entry name" value="VACUOLAR MEMBRANE AMINO ACID UPTAKE TRANSPORTER FNX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="63"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="256"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="285"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="324"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="368"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="403"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="436"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="503"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="64"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ28435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="533" mass="55751" checksum="034E2B4EC300E7AA" modified="2011-01-11" version="1">MTGSADGTSVPTETSPLLPNSDSGVVNDNGTLENGPANGVPAVAQDANDNRDGNPEMAKKMHILLPAVGIGIYLCAVDQLLTVATYAKIGSELHALKNTSWLATAYYITLTSFQPLYGKLSDIFGRKECLLFAYVIFGLGSLGCGLAQSFAQLCVARAVAGIGGGGMNSVVAILLSDIVPLRDRGVWQGYLNIIFAAGTSTGAPLGGLLADTVGWRWSFAGQVPLCALAFLAVYFVLDLPPADHAHWRDKVRRIDFLGAATLVAAVVALLVGLDSGSNNGWSSRATVAGLASAPVLFAVFVLVEMRVASHPFAPGHIIFDRSLFACYLANFFGIAGHIASIFFLPASFQAPVQQYETLQTIPREVRRLALTVLAYGLMVLAVAPTVAALGASSSAGVVGSMALLALGGGAGITTTLVALLSNAAVQDTAVVVACSYLFRSLGSSIGISVCSAVLQQVLRTQLASRLSDGDEARRVEERVRESLDYIRELPPAVAAEVRASYQVATLGAMVPVALLLVLAFVSTFFIREKALGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCA3</accession>
    <name>E3QCA3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Coatomer subunit delta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">GLRG_03635</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 10">Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10 11">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10 11">Cytoplasmic vesicle</location>
            <location evidence="10 11">COPI-coated vesicle membrane</location>
            <topology evidence="10 11">Peripheral membrane protein</topology>
            <orientation evidence="10 11">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10 11">Golgi apparatus membrane</location>
            <topology evidence="10 11">Peripheral membrane protein</topology>
            <orientation evidence="10 11">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092511.1">
        <property type="nucleotide sequence ID" value="XM_008094320.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCA3"/>
    <dbReference type="STRING" id="645133.E3QCA3"/>
    <dbReference type="GeneID" id="24409000"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03635"/>
    <dbReference type="eggNOG" id="KOG2635">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019988_3_0_1"/>
    <dbReference type="OrthoDB" id="10266042at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051645">
        <property type="term" value="P:Golgi localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09254">
        <property type="entry name" value="AP_delta-COPI_MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14830">
        <property type="entry name" value="Delta_COP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000003">
        <property type="entry name" value="Coatomer subunit delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1170">
        <property type="entry name" value="Mu homology domain, subdomain B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036168">
        <property type="entry name" value="AP2_Mu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027059">
        <property type="entry name" value="Coatomer_dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028565">
        <property type="entry name" value="MHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10121">
        <property type="entry name" value="COATOMER SUBUNIT DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10121:SF0">
        <property type="entry name" value="COATOMER SUBUNIT DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00928">
        <property type="entry name" value="Adap_comp_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49447">
        <property type="entry name" value="Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51072">
        <property type="entry name" value="MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="5 10" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="7 10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MHD" evidence="14">
        <location>
            <begin position="277"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="167"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="136"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU366052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EFQ28491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="515" mass="57406" checksum="D6BEC2953FDF8922" modified="2011-01-11" version="1">MVVLAASICTRGGKAVLSRQFREMPRSRIEALLASFPKLADSGTQHTTVEQDNVRFVYQPLDELYMVLITNRQSNILQDIDSLHLFAQVVTSTCKSLDEREILKNAYELLSAFDELVTLGYRENLTISQIKTFLEMESHEERIQEIIARNKELEATEERKRKAKQLEMQRKESARAGRVGGGMPRTPVYPTYTPPTRPTPTDTYDSYEAEKNKTFNKLNAPKGKGMQLGKKSKTTDMFERVRGEMGPEVDDTPLITPSAAHVPEPAAEPRVSSTLDRDAIHVVVNEAISAKLSREGAINSLAIVGDLSLRISDPTLTKVKLNLTANASHGAQFRTHPNVDKNLFNSSKVIQMSNTARGFPTNQSVGVLRWRATAKADDASACPITFTVWINKDADKYNMTVEYELTGGDTLRDVSVIIPYQVSEPVVSSFDASYEVSGDSLEWNIGTVSDENPTGSFEFEAETNDENDFFPMTVRFSKTSPFIDVDVSSVSLLEEDEEVTFSKEVKSNADNFLIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCL7</accession>
    <name>E3QCL7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Histone acetyltransferase type B catalytic subunit</fullName>
            <ecNumber evidence="3 9">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">GLRG_03749</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-lysyl-[protein] + acetyl-CoA = N(6)-acetyl-L-lysyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:45948"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10731"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="2.3.1.48"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the HAT-B complex composed of at least HAT1 and HAT2. The HAT-B complex binds to histone H4 tail.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the HAT1 family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="3 9"/>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092625.1">
        <property type="nucleotide sequence ID" value="XM_008094434.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCL7"/>
    <dbReference type="STRING" id="645133.E3QCL7"/>
    <dbReference type="GeneID" id="24409114"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03749"/>
    <dbReference type="eggNOG" id="KOG2696">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036024_2_1_1"/>
    <dbReference type="OrthoDB" id="10253098at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004402">
        <property type="term" value="F:histone acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031509">
        <property type="term" value="P:subtelomeric heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.360.10">
        <property type="entry name" value="Histone acetyl transferase 1 (HAT1), N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019467">
        <property type="entry name" value="Hat1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037113">
        <property type="entry name" value="Hat1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017380">
        <property type="entry name" value="Hist_AcTrfase_B-typ_cat-su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013523">
        <property type="entry name" value="Hist_AcTrfase_HAT1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12046">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE TYPE B CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21184">
        <property type="entry name" value="HAT1_C_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10394">
        <property type="entry name" value="Hat1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038084">
        <property type="entry name" value="HAT-B_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histone acetyl transferase HAT1 N-terminal" evidence="14">
        <location>
            <begin position="7"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with histone H4 N-terminus" evidence="11">
        <location>
            <begin position="44"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with histone H4 N-terminus" evidence="11">
        <location>
            <begin position="217"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="449"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="449"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="10">
        <location>
            <position position="289"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="254"/>
            <end position="256"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with histone H4 N-terminus" evidence="12">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR038084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR038084-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR038084-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR038084-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF10394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EFQ28605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="483" mass="54892" checksum="569C31C6DF818234" modified="2011-01-11" version="1">MAETDEWSANATESLNISLVAPATGATKTIASFNPKFTYSIFGDDERIFGYKDLRIDLRYRTFDMRPNVKVSYGKKFQSVGETEAADVNATLKEHLPLVAFESAREFNTGAQSQPDGWTPPGAFHSSYEGHDGTYEVWKGSLADPAVRQIVTRVEALIPMFIEGGSYISRDANDEEDPWKVPEDANRWTVFFLYRKQTSPEASGRPSYTFVGYATVYRFFCFRPLTPPSSEWDLPKEEFNLLEELPCRSRLSQFLILPPFQGKGIGARLYKTIFEHYYNNPQTLELTVEDPNEAFDDMRDLADLTFLRSLPEFSNVKINTSIALPNPPSGTVPKDLVDQELLRNLRQKTKIVDRQFKRLIEMQTMSQLPASVKVGFGEEQKAKPTKEEKHHYHLWQLFVKQRLYRQNADVLGQLDQSERSEKLNEALSSVELEYARLLDWHARWEEHAAAASAAAAESGGSKRKSVDDAEDQGASKKVRIEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCT4</accession>
    <name>E3QCT4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">GDP-mannose transporter</fullName>
            <shortName evidence="7">GMT</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_03816</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 7">Homooligomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Golgi apparatus membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Cytoplasmic vesicle membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Endoplasmic reticulum membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the TPT transporter family. SLC35D subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092692.1">
        <property type="nucleotide sequence ID" value="XM_008094501.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCT4"/>
    <dbReference type="STRING" id="645133.E3QCT4"/>
    <dbReference type="GeneID" id="24409181"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03816"/>
    <dbReference type="eggNOG" id="KOG1444">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025360_1_2_1"/>
    <dbReference type="OrthoDB" id="417037at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030659">
        <property type="term" value="C:cytoplasmic vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00803">
        <property type="entry name" value="nst"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="210"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="243"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="280"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="309"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="335"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ28672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="384" mass="41713" checksum="1B57C6F5B33168D0" modified="2011-01-11" version="1">MSDKKNEDYELNSSESFGEKDGFLSRPPPRTRPALASPISKIDNSPGIAILAYCFSSISMTVVNKYVVSGQFWNLNFLYLAVQSIVCILTIVVCKNLGMITNLAPFDTDKAKKWFPIALLLVGMIYTGTKALQFLSVPVYTIFKNLTIIVIAYGEVLWFGGSVSPLSLLSFGLMVLSSVVAAWADVAHALGGSSHTAEASAAVSTLNAGYAWMGMNVCCTAAYVLGMRKVIKKMNFKDWDTMFYNNLLTIPVLIVCTLLTEDWSSANVQKNFPVETRNSLFVGMVYSGLCAIFISYCSAWCIRVTSSTTYSVVGALNKLPIAISGLVFFDAPVTFGSVSAIIIGFVSGIVYAWARIRQTEASKMSLPTTQPMSASAQSNRDANK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCW8</accession>
    <name>E3QCW8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RWD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_03884</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092760.1">
        <property type="nucleotide sequence ID" value="XM_008094569.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCW8"/>
    <dbReference type="STRING" id="645133.E3QCW8"/>
    <dbReference type="GeneID" id="24409249"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03884"/>
    <dbReference type="eggNOG" id="KOG4018">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084528_0_1_1"/>
    <dbReference type="OrthoDB" id="277175at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004860">
        <property type="term" value="F:protein kinase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034198">
        <property type="term" value="P:cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031333">
        <property type="term" value="P:negative regulation of protein-containing complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903833">
        <property type="term" value="P:positive regulation of cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000075">
        <property type="entry name" value="RWD domain-containing protein (Gir2)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040213">
        <property type="entry name" value="GIR2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032378">
        <property type="entry name" value="ZC3H15/TMA46_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12292">
        <property type="entry name" value="RWD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16543">
        <property type="entry name" value="DFRP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00591">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RWD" evidence="3">
        <location>
            <begin position="8"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="108"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="220"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ28740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="229" mass="26396" checksum="8523BBB6B0D3EBCF" modified="2011-01-11" version="1">MGREEQVEEREVLESIFPEEITDISETEFRIQIALDVPGEEDEPPTMFLQVRYPEAYPDEPPTLDLQSVPNAAPYEWFNVSEDRERLLEGIEETIQENLGMAMVFSLVSALKEAAEALIEERKQAREKEHEERAAELEREENKKFHGTPVTPETFLKWRAGFIKEMEEQKQREEEERLAELKKAKIKEPVKLTGKQLWERGLVGKVVDEDEEDGAGLAEGVDRLKVEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>E3QD29</accession>
    <name>E3QD29_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">GLRG_03945</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
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            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
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            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
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        <property type="protein sequence ID" value="EFQ28801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_008094630.1"/>
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        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="P:positive regulation of mitotic cell cycle phase transition"/>
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        <property type="project" value="UniProtKB-ARBA"/>
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    <dbReference type="FunFam" id="1.10.510.10:FF:000664">
        <property type="entry name" value="Serine threonine protein kinase"/>
        <property type="match status" value="1"/>
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    <dbReference type="FunFam" id="3.40.50.2300:FF:000139">
        <property type="entry name" value="Serine threonine protein kinase"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Serine/threonine-protein kinase cek1"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
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        <property type="entry name" value="AGC-kinase_C"/>
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        <property type="entry name" value="Ser_Thr_kinase_AGC"/>
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        <source>
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        <source>
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        <source>
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        </source>
    </evidence>
    <sequence length="1890" mass="207034" checksum="CDE3998813DBC50A" modified="2011-01-11" version="1">MEPPQPNMLAPPAVTALRTQAGVMERSLSEDIREEREELREAAEQTLNVIVDLNLDGTIRWVSPSWADVIGTQPDSVKGTAIADLIVSDNKTVFADTVESMKTDDSRSQRVRFAVAMGPLSRLLPIDIVQDEDLDGAEKPALEAIDLEAQGIMVYDGVSGGESHTMWMIRPYIAPREIKIDLPAVIVDSLGSGAEVLASYLTQLAESGIDDPQNHPPPLPVLCRICERQISPWWFEKHTDLCLQEHRAEMDVQMAQDSLTDHRHSIVKVLDALEARKSRPLPGDQLSGPAAEYKGLPIGPPLSAQSSPGNSVSQSRERSGGFGHSRARSFAIRRPQARIVELLLDLCDTAIEISTPAVKEVSSQNPGEIRTQSPQSESRISQVMQWQSPSTNTLEQEQGLALLCADTEKAAKTKVEAVFRHRKIIEYAERIRIEFAVIVQDCIDEAMRKAARIAAGRLSDSTEEEEEEEEEDEEATPAHEELFFQGSFDNPSALAVALQNVGLNDTTDRIRPTSFVGSARSSSPRECLTPRSNLGGINPAAPARESRRESLLFESDNGDSDGSIRSSSVTSRQPPRTDSPISEFGDLRRAASSRQHHRRSIILPGASSPRRQESPSRLNQPSSPLRIIKPRNFPFPQDGVTSPEASPLLPGSDFSSPAHLPVSHHRRQSSTAMSEFVMKGPPSPRMVAHQPPPQARPSPPSIKDFEIIKPISKGAFGSVYLSKKKSTGEYFAIKVLKKADMVAKNQVGNVKAERAIMMWQGQSEFVAKLYWTFSSKDYLYLVMEYLNGGDCASLIKVLGGLPEEWVKKYLGEVVLGVEHLHSRGIIHRDLKPDNLLIDQKGHLKLTDFGLSRMGLVGRQKRALDSQNLDPTPDLLKQGPFARSSSLASSRSTSLDLHGHAHSPSTTPQMTPDTGSSGGQPSYFALGGPEARRLSSHRSDSGGSETLARMLNNFSLNDQEHNPPTQSSHPVPEDANDSAGQASPDMAVLHHASTQSSVDFLGKSTPPQSSMMPPPMALFNPEDTNRRFVGTPDYLAPETIKGEKQDETSDWWSVGCIMFEFLYGFPPFHADEAEEVFENILARKIQWPDENECEPISDEAKDLINKLLCMEPQSRLGANREDKFPCGGDEIRSHPWFEAINWETLLQDEAQFVPQLEHPEDTEYFDARGAVLQSFAEEMEDQLSPPVSGTGSDYHDRPHDALSRVRSQVNSIKRNLMPLHIPPHVRDLKSRRLSEPVVADDFGSFTFKNLPVLEKANKDVIQKLRAEALASQNKPTVISPGGSVTSPGANLEGSPVLSNPVQRTISNAKNRPQSPSGLSHANSSPSRASQPSSPLLVSFVAGQGSEGRRKVSSNSSSLSQQSGVSHQPTSLDIPRVPPSLQKAATSAAASPVKGRGSGPPPPLALSPQKLVSTPRQASSSRSRSLTVGSQEGSPIASDVLSHHRNRRSQVFDMSPSSSDNEGDKHNALLRVQRRRQSSRRLSQIAFDGGPMFRPLDVLICEDHPVSRMVMEKLLEKLRCRTISVANGSEAVRYAMSEIKFDIIFLEYRLPQINGADVARMIRETKNTNSHTPIVAITAYLKELQAPHYFDSLVEKPISSSKLTEVLKNLCQWKPESPGINYSMSLGHSQPVPSGLRQTSCRADDSPTSSSSLYAGRPGSSLVTSSREDSISSSLFGDSESVSTDDVPVVISRKATGDWNEGGLGITQDESAPPVKSPKSLPPLVTQQSAPGQLEHTRRSVPQHSVEKLKARKEHIEKRLAEGTDSADDEDEELGLGRDKLFRGKPLLPSSKLGIEMMRADSHDSVTIGSESTPEPITQVVTPSKEIDMPSYETLRDASTRTPPDSGVNAEEKSNAPDVDETPRPQPTNREDVADEEPTPRPLERSGLLGYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDQ5</accession>
    <name>E3QDQ5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_04137</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ28993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093013.1">
        <property type="nucleotide sequence ID" value="XM_008094822.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDQ5"/>
    <dbReference type="GeneID" id="24409502"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04137"/>
    <dbReference type="eggNOG" id="ENOG502RES9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2223082_0_0_1"/>
    <dbReference type="OrthoDB" id="284184at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ28993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="106" mass="11803" checksum="7A596A7B6264E98D" modified="2011-01-11" version="1">MTSIPSKTLEISPGITYRYFYSRASRADLPTLLFGADELELEAPVLVVGCGRDEMTAAGLQDEMTRPWARAGYRFEVLDTGHWVMLEDTAGTNRLLEEFVDGLGKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEL5</accession>
    <name>E3QEL5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PAR32 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04465</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093341.1">
        <property type="nucleotide sequence ID" value="XM_008095150.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEL5"/>
    <dbReference type="GeneID" id="24409830"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04465"/>
    <dbReference type="eggNOG" id="ENOG502S3S2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082191_2_0_1"/>
    <dbReference type="OrthoDB" id="3063476at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053203">
        <property type="entry name" value="Cisplatin_resist-associated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022024">
        <property type="entry name" value="DUF3602"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34693">
        <property type="entry name" value="PROTEIN PAR32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34693:SF1">
        <property type="entry name" value="PROTEIN PAR32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12223">
        <property type="entry name" value="DUF3602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="141" mass="14635" checksum="D3E159B26CEC05FA" modified="2011-01-11" version="1">MLASSGRGGAGNMTENSPKITPKDLETPTLKTSVVTTGRGGSGNMAKNSDPYETRLRQDVEAVPRRNSGGATHYGRGGANVFKGSPEEEAAARKAGAEGAGAIDDDEQQPALRKSPSPEDKGNNGLAAKGKQWLNNLTKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QG18</accession>
    <name>E3QG18_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GATA transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_04997</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093873.1">
        <property type="nucleotide sequence ID" value="XM_008095682.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QG18"/>
    <dbReference type="STRING" id="645133.E3QG18"/>
    <dbReference type="GeneID" id="24410362"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04997"/>
    <dbReference type="eggNOG" id="ENOG502QUGJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001743_2_0_1"/>
    <dbReference type="OrthoDB" id="3199820at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000183">
        <property type="term" value="P:rDNA heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030466">
        <property type="term" value="P:silent mating-type cassette heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057725">
        <property type="entry name" value="Ams2-SPT21_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042403">
        <property type="entry name" value="Spt21/Ams2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39147">
        <property type="entry name" value="PROTEIN SPT21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39147:SF1">
        <property type="entry name" value="PROTEIN SPT21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25823">
        <property type="entry name" value="Ams2-SPT21_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ams2/SPT21 N-terminal" evidence="2">
        <location>
            <begin position="4"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="653"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="701"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="859"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1022"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1215"/>
            <end position="1239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="193"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="235"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="279"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="480"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="559"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="673"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="871"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="891"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="911"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="925"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1022"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1106"/>
            <end position="1122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ29853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1257" mass="136622" checksum="05C257BE0C0CBB71" modified="2011-01-11" version="1">MGVLTKTMGLKVTYAFADSGESFLARHPELLTVRTVPIDDKLTVGMVDLKMCVQAVVKCSPELLSDVTRDFAVYAYDYSEPDEPLVGQGFLGWIVNNADGKQIIGRATRNPLSAFSNGVKEILEIKLKLKPVAAMVQPQYESESRPDLRHSYQRSESHMSVEVQPTRPADGALTPSSHAEWNSFMQSNPQMGSQHHPQSVPSPHQPSMHLDFQQQQQQQQQQHFQRSNSFSYGAPPQHQHQQILPQPHQPTQNSDGPNRVAPTPVDTATETQVNPPSRPSSRASNPSSRKSRATGRPRGRPRKQPRAESQGNTSGYEDGTDGDEGPAKKKRATMTQVTSNINAPFGGGPESLRVTASTAGSLRTLRPMGMPVEAPMGSHMQDVPRAPTPVPDRGPMMPQAGKPTNGSKLRRQSNLSQAATPPSQPQFSEPPFALSPSQQDGRSPDSEAVSPMYSEDSPAAIGSSPPVPRNTSFVRSSPPASSPILPPMPMPQPDSGFMSGGMDDLFDGEGVKQQLPKAVVPPVRRSNSNVTKERRSRSGIPIQVFQLAAQPSAEADAATRSNRQQSAPRPPTSTLSLEPSLPPMSRTVSDSRLALPSPSQPAEKEPSPQQEELVVAVKPEVDIDGQSAPKIETQQPDDGLELGLEKLAQAVQGMASESALPEPQMAPDATATFARPSAPPSLSRSTSSGFSLALPSVAASDPIGPIALPAPAPPDITSFSEAPCPPSDALQPPRSPPQPTRSNKNYVKKQAIREKLLQAIASGQTPMYCSNCGAIETPTWRKIWTQEHEGVPEFTEFSDKPGRITAILVLDRDADEKPTKYQIIKKALLPKEDKSDWKEHMLCNPCGIWLSKWKAHRPQEKWEKDSARLGQQRRPRGTGRAPRPPRAKKSGSANPLNPTSEAYNTTDPIGPDDRGVSPMDESRSRGVSQVSNANDASQRSMSQFSASQPPEYQGSRPTSPGNISNPGSTHSRGSGTAKSPITIDNADVEDMGATRRLLFPSPRKDGVSKALSDLAVNIMQTAPDSSRSAQVIQNREVPIKGPGKDAAASKVSGMNKENLAAPEDDLEDLFRSPLIRPSTPPPKERAPNNGPFKTPTRPTPSHRPITRSVTRSVSRSMRSGDLLRSPAAVRRTPTRTPRSAKGLLRRSPRLHNDEFTQMELALEEYLQTQSLDHQYDSDMLEAMNRALAESMDAPGSNFDITNMVLESSCQLEFGDLLGSPSRPTPRPARQQVSDFEDWDTWESNMRARQAAEDSRSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGL8</accession>
    <name>E3QGL8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05150</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ30006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094026.1">
        <property type="nucleotide sequence ID" value="XM_008095835.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGL8"/>
    <dbReference type="STRING" id="645133.E3QGL8"/>
    <dbReference type="GeneID" id="24410515"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05150"/>
    <dbReference type="eggNOG" id="ENOG502RES8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_142375_2_0_1"/>
    <dbReference type="OrthoDB" id="5239281at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="152" mass="15914" checksum="155B1BA820945DAE" modified="2011-01-11" version="1">MPPKKNAASADEAPVLCLNENETVFVKAIFDSMNSRPDVDFDKVAGITGLANAKSAKDKFRVISKKHGWSSTDGSGGGASSPSKGPLSANTTAKVKKTPVKKKGTAQRKKKVKAAEPEDSDADEDISAKLESDSDGQKAAKDELMNGSSDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGN8</accession>
    <name>E3QGN8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribose-phosphate diphosphokinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_05170</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ribose-phosphate pyrophosphokinase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ30026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094046.1">
        <property type="nucleotide sequence ID" value="XM_008095855.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGN8"/>
    <dbReference type="STRING" id="645133.E3QGN8"/>
    <dbReference type="GeneID" id="24410535"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05170"/>
    <dbReference type="eggNOG" id="KOG1448">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033546_0_1_1"/>
    <dbReference type="OrthoDB" id="413572at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097268">
        <property type="term" value="C:cytoophidium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002189">
        <property type="term" value="C:ribose phosphate diphosphokinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004749">
        <property type="term" value="F:ribose phosphate diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006015">
        <property type="term" value="P:5-phosphoribose 1-diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000030">
        <property type="entry name" value="Ribose-phosphate pyrophosphokinase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000056">
        <property type="entry name" value="Ribose-phosphate pyrophosphokinase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029099">
        <property type="entry name" value="Pribosyltran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01251">
        <property type="entry name" value="ribP_PPkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210:SF36">
        <property type="entry name" value="RIBOSE-PHOSPHATE PYROPHOSPHOKINASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14572">
        <property type="entry name" value="Pribosyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13793">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01400">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribose-phosphate pyrophosphokinase N-terminal" evidence="4">
        <location>
            <begin position="6"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="103"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="154"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="111"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ30026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="444" mass="48517" checksum="87E22422306C74E1" modified="2011-01-11" version="1">MVRNIIVLGGNTHPELVNSVCNNLGLNPCERVLSKFSVGESRCEIKDSVRGKDVFIIQTASGSVNDGFMDLCIMISACKTGSAKRVTAVMPLFPYSRQPDVPYRKSGAPLSKSSTEASKNYTFESVPSTPGPGIARSAGLPNGIDGIASKLAKSKLNEERTNGMNGSSEYFKNGEHKTNGNSNGNGRPHQDSVSSQFSYTTHDYENQNHINGFQSKPGYKQWVAQAGTLVADLLTCAGADHVVSIANDCRMDLHDPQYQGFFDVPVDNLYGKPLIKRYIQQNIPHYKDAVVISPDAGGAKRATAIADELDMAFALIHKERRPTKYTEQRNASMMLVGDVKDKVCILVDDLIDTGNTITRAAKLLKKEGATHIYALLTHGILSGDAIPRINASAIDKMVVTNTVPQRDHMRLCPKLEYLDVSPVFAEAIRRVHHGESISVLFQHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QH54</accession>
    <name>E3QH54_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_05360</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697348">
        <property type="protein sequence ID" value="EFQ30216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094236.1">
        <property type="nucleotide sequence ID" value="XM_008096045.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QH54"/>
    <dbReference type="STRING" id="645133.E3QH54"/>
    <dbReference type="GeneID" id="24410725"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05360"/>
    <dbReference type="eggNOG" id="ENOG502QW04">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_47_0_1"/>
    <dbReference type="OrthoDB" id="190201at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050471">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433:SF5">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433">
        <property type="entry name" value="HYDROLASE, ALPHA/BETA FOLD FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180408" description="AB hydrolase-1 domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="66"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ30216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="289" mass="30562" checksum="43E49EB2A7B0FA80" modified="2011-01-11" version="1">MHFNALLAAALTGSVSGLALRQAIPVWETLPATPDLPSPISTARTPINGIEMWFQKYNEEAGGVPIVMDHGGLGYSAYFGSVITRLVNAGHYVIAVDRRGHGRSTYNADDVFTYDQMAADVTALLAGAGVTRYNVVGWSDGGIVTLATLLDPTAAGTINKAFLFGATANPEQTNTSFSQTAIFSEFVSRCAAEYAVLQPTANFTDFGTKVATMEATLPQFTDAQLGTIDGSKVMIADGDREEAVNLDVPGLLNKAIPGSSLTILTGVSHFAPLQDPDQFTKAVTDFFNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QH65</accession>
    <name>E3QH65_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C6 zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_05371</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697348">
        <property type="protein sequence ID" value="EFQ30227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094247.1">
        <property type="nucleotide sequence ID" value="XM_008096056.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QH65"/>
    <dbReference type="GeneID" id="24410736"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05371"/>
    <dbReference type="eggNOG" id="ENOG502S37P">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016172_0_0_1"/>
    <dbReference type="OrthoDB" id="3597252at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF46">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ30227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="531" mass="59706" checksum="1A65289CDCB4F98E" modified="2011-01-11" version="1">MLPAPESRCVENLALSNPFDDNADDENRLVLGRRPIERGTKVDGYIKFHNEKRKPAKESGIAVFMYKGSGQEPSPRSTLAMYLSPQYMGEMGLQDQDDKSLFAFYLKAWCPGRSVLDKTNCWFENIPRMASQDSCVRSAILALAGTYVLDYQPRERIRQITQSHYKNAVILLGMALREARNQLPSESEADCMVAAMGVLNMIDVVSPEQRRPPNRVPRWLEGARLACRILDATEPGHRYWKPVNIQPSEAQAGNMIIAGRAAILALPMAPLDLAATENRQFAWLLQGSEHDVHRVHGGCGMSPTLLHRFSQITHMSAFLGADPEDSEFVIKPGADKLLEELRNLHQWTDGSSSQPGNSRDSLHPRDLLASIKLDKHGLIMDRSSMTEVTAEAWRLAAVIYLRCRLERLPRCHPDVLFPVTELAKCIRMMPTSGTFFTAQSPFFPVFLLGVVAIHEAHVQCALNWFQSVISTSCRSSVPPAFQSLNRIRAWMALNTRDVNRSELPRRISERHPWWETLVSHIAATEGTLCLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHE3</accession>
    <name>E3QHE3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">hydroxyacid-oxoacid transhydrogenase</fullName>
            <ecNumber evidence="4">1.1.99.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_05449</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(S)-3-hydroxybutanoate + 2-oxoglutarate = (R)-2-hydroxyglutarate + acetoacetate</text>
            <dbReference type="Rhea" id="RHEA:23048"/>
            <dbReference type="ChEBI" id="CHEBI:11047"/>
            <dbReference type="ChEBI" id="CHEBI:13705"/>
            <dbReference type="ChEBI" id="CHEBI:15801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="EC" id="1.1.99.24"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>4-hydroxybutanoate + 2-oxoglutarate = (R)-2-hydroxyglutarate + succinate semialdehyde</text>
            <dbReference type="Rhea" id="RHEA:24734"/>
            <dbReference type="ChEBI" id="CHEBI:15801"/>
            <dbReference type="ChEBI" id="CHEBI:16724"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57706"/>
            <dbReference type="EC" id="1.1.99.24"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.1.99.24" evidence="4"/>
    <dbReference type="EMBL" id="GG697348">
        <property type="protein sequence ID" value="EFQ30305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094325.1">
        <property type="nucleotide sequence ID" value="XM_008096134.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHE3"/>
    <dbReference type="STRING" id="645133.E3QHE3"/>
    <dbReference type="GeneID" id="24410814"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05449"/>
    <dbReference type="eggNOG" id="KOG3857">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007207_0_7_1"/>
    <dbReference type="OrthoDB" id="339764at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047988">
        <property type="term" value="F:hydroxyacid-oxoacid transhydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08190">
        <property type="entry name" value="HOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1970:FF:000009">
        <property type="entry name" value="Fe-containing alcohol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1090.10:FF:000003">
        <property type="entry name" value="Probable hydroxyacid-oxoacid transhydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1090.10">
        <property type="entry name" value="Dehydroquinate synthase-like - alpha domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056798">
        <property type="entry name" value="ADH_Fe_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042157">
        <property type="entry name" value="HOT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496:SF83">
        <property type="entry name" value="HYDROXYACID-OXOACID TRANSHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25137">
        <property type="entry name" value="ADH_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56796">
        <property type="entry name" value="Dehydroquinate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA" evidence="10">
        <location>
            <begin position="78"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="Fe-containing alcohol dehydrogenase-like C-terminal" evidence="11">
        <location>
            <begin position="300"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="32"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF25137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ30305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="499" mass="53824" checksum="FE95C73076075470" modified="2011-01-11" version="1">MTPSLRVVPNAASRAVSLLRTIQAHPPSCPCHTNPGHHHHHNPLNFTPRPLRTRNSSRGFATPVDGPQKEYAFEMAASSIRFGPGSTQEVGMDFANMGAKRVAVVTDPVVDGLFAMQQVREALDREGINYKVYNQTRVEPKDSSIREAIDWARPFSPDAFLAVGGGSVIDTAKLMNLYSCYPDAPFLDFVNAPLGNGRPVDKALKRLIAVPTTAGTGSETTGTAIFDLVSKRAKTGVAHRNLKPTLGICDPLNTRTMPAAVKAASGLDVLCHSLESWTAIPYYERVPRPKNPILRPAYQGANPISDVFSFHALRATVKYLPRAVKNPDDYEAQSEMLLAATLAGVGFGNAGVHLCHGMSYPISGQNPGYQHAGYKVSYPIIPHGVSVAVTAPAVFRFTGASNPERHLQAAEVFGVDISRVRKEDAGAVLADALTKFLAELGDQPAGIKALGFGTQHLDDLVEGTIPQARVLMMAPGLETELEKEREQLRGLFEDALVHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHN2</accession>
    <name>E3QHN2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase S33 tripeptidyl aminopeptidase-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_05514</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697349">
        <property type="protein sequence ID" value="EFQ30370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094390.1">
        <property type="nucleotide sequence ID" value="XM_008096199.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHN2"/>
    <dbReference type="STRING" id="645133.E3QHN2"/>
    <dbReference type="GeneID" id="24410879"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05514"/>
    <dbReference type="eggNOG" id="ENOG502S0WE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013364_5_2_1"/>
    <dbReference type="OrthoDB" id="425534at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013595">
        <property type="entry name" value="Pept_S33_TAP-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051601">
        <property type="entry name" value="Serine_prot/Carboxylest_S33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248">
        <property type="entry name" value="2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248:SF25">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08386">
        <property type="entry name" value="Abhydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S33 tripeptidyl aminopeptidase-like C-terminal" evidence="4">
        <location>
            <begin position="546"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="170"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ30370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="674" mass="74237" checksum="406F2498C7EE651B" modified="2011-01-11" version="1">MEKGRGSGAQPPSSPPPRRFSKPWLLVGALALIGLGHIHSPQPQLEAWQRHGGGHSRTHSSKSVADSPFGQFPLPKDPFRFIPCTNASVPPPLDDTHPEQTWVTLFDPDPSNWSWGNKSDSVDLDDDPYAGRGIYLCGYLDVPLDYTNASESRIVRLAVTKYQVSGLARVGEPADDDQNPVPGAKSKRTIVIEPGGPGSSGTSYAWRAAEQVTKRFSDSTFDVLGWDPRGVNITQPSISCFPYDVDRDHWSLATGQYLEVSDVKRQLNVADAMNDATLKACWELHGDLGRFLGTGLVARDMEEIRKALGEDELTGYLVSYGTGIGQTYANLFPDSVGRIILDGTEYVRDHRLLGGFGWTALDNATDAWHDGFLGECINAGPEHCALAKSEDDQPVVLEDLNIRMRSLISSLIDRPVVGYTKASGPSIVTYSGLVGGLYSSMYNAASWPALAKMLYELEQGNSTLATAFLERMSWQYDPTLLATTKKRPSSDELGTLVVCADSYDAPLPPDGLDWWASLWANMTAKSWISGNSRFFNVLPCQHFTKYWPEPAGVYRGDLNHTLKNPVLLIAETYDPATPLRNGRRLLDEMGRNARLIVHHGYGHSSRDTSNCTDSIAKTYILEGELPDEAETACYANEKPYLYGVKDKGVSVLAEGAMDPIDVWRQHLREMAFMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QI55</accession>
    <name>E3QI55_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_05814</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094690.1">
        <property type="nucleotide sequence ID" value="XM_008096499.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QI55"/>
    <dbReference type="STRING" id="645133.E3QI55"/>
    <dbReference type="GeneID" id="24411179"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05814"/>
    <dbReference type="eggNOG" id="KOG1262">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018354_1_2_1"/>
    <dbReference type="OrthoDB" id="2151789at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF54">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179747" evidence="5">
        <location>
            <begin position="24"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="81"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ30670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="520" mass="55050" checksum="F2654DF0EA614B43" modified="2011-01-11" version="1">MVRFSSFFAQLLAVVAAPVAAAAGELADADTAATSAVVSSLRGSEKVACGLLSFRYPGQTFFAGSDGYTYETRTQYWSARAYDTPACVFVPQNAQQASFAVATLTLSLTQFAVRSGGHMPVVGYNSIGSSGVLLSTSNLTVLALSEDKNTVSVGAGLRWRDVYSYLSGSGLAAVGGRIGGVGVSGLLLGGGISFYSNQYGFAADNVVCYQAVLSSGAIIEATATNAYSDLFWALKGGGNSFAIVTRFDLKTVKSPKVWVGISQYAQPDSAKYLDAVYNFGKYGSADGKAAIIPTILTYPSYNITAYAAARFYDSDTNSATAFENFTSPVLTPVNDSYTLQPLANYVSAVDALQPTGLRQEFRVLSLVVDRDAVEYVHNAFLAAASSKLTGIVGLSASITFQPITKEFIQQGIAQGGNPQGVDPAKAPYFWVVENLTWQEAKDDEAAQSFADTVTADMEAGLEARGVAGGYMYLNDAGKGQKIFQSYPAANLAKLKAIRTKYDPLRIYTNLLVGGWKVLDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIF6</accession>
    <name>E3QIF6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">alcohol dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_05710</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.1" evidence="3"/>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094586.1">
        <property type="nucleotide sequence ID" value="XM_008096395.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIF6"/>
    <dbReference type="STRING" id="645133.E3QIF6"/>
    <dbReference type="GeneID" id="24411075"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05710"/>
    <dbReference type="eggNOG" id="KOG0023">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_20_1_1"/>
    <dbReference type="OrthoDB" id="1879366at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08297">
        <property type="entry name" value="CAD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000039">
        <property type="entry name" value="Alcohol dehydrogenase AdhP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940:SF3">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="9">
        <location>
            <begin position="16"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ30566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="358" mass="37767" checksum="71C1C7C03420D9F7" modified="2011-01-11" version="1">MDTHKAAVLTSPQRTDEIPTFSVRDEPRPVPGANEVLVRLSATGLCGSDLGMAMGHFGPVGNILGHEGVGRIAALGSNVAALDQSVQVGQRVGVAWTRDICSTCETCVDLVNEGETRCEKSLHSGKAYDGTFAQYTLVPLRYLARLPSQFDGLPDEEIAPILCGGVTAYKAIKGCNVTPGQWFAVSGAGGGVGSLAVAYAHAMGYRVIAVDAGPEKGEICKAQGAEHYIDVATSGTLGEKIRQATGGYGAKAVVVTATATAAYQEAYELLAPFGTLMCVGILSAEARVTFNPLWLIAKGWKILSSSVGTRADVLEALEFVRRRAVVPKVQVGRLEDIQDLVQAMYAGQLKGKWVLKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIG3</accession>
    <name>E3QIG3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">MATE efflux family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_05717</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094593.1">
        <property type="nucleotide sequence ID" value="XM_008096402.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIG3"/>
    <dbReference type="STRING" id="645133.E3QIG3"/>
    <dbReference type="GeneID" id="24411082"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05717"/>
    <dbReference type="eggNOG" id="KOG1347">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012893_1_2_1"/>
    <dbReference type="OrthoDB" id="2126698at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990961">
        <property type="term" value="P:xenobiotic detoxification by transmembrane export across the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13132">
        <property type="entry name" value="MATE_eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045069">
        <property type="entry name" value="MATE_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048279">
        <property type="entry name" value="MdtK-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11206">
        <property type="entry name" value="MULTIDRUG RESISTANCE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006603">
        <property type="entry name" value="DinF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="123"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="160"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="190"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="297"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="342"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="383"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="411"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="444"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ30573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="481" mass="51661" checksum="5E156D4301EF1232" modified="2011-01-11" version="1">MDSRDHDDRAGETTPLLSDQPYQKPDDAEPAEGGWLAEAWLLCRYSLPLIATYLLQYSFTVITTFVAGHLSADDLAAASIGLTTMNIVGLAIYEGMATALDTLCAQAHGSGRLTAVGLHVQRMLVLMALATVPIGLFWVFSPSILGLFVKQHHLAVKAGLFLRVSLIGMPGYAAFEALKRFLQAQGDFKSAMVVLIVCAPLNAFLSWLFAFHLGMGLEGAALGQALANNLRAVFLLAYIVFWGRWSHSCWGGFSREAFAEWGAPVRLSVAGAAVNIGEWAAFEILTLSTSYLSTEHLAAQTILTTISVVMWHIPFSISVAVSTRIGHLIGAGLVSTARRAAAVCAVVVVVVGVLDAILVFVFRNQLGLVFSEDAVVRRLTTNSMLAVAAFQLIDSIISGCNGVLRGLGQQSVAACIVFVVNYLAAVPVAVWLELGTPNMELNGAWIGLGSGMVVIAIIECIYMKTIRWQDCVEKVKEREGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QII1</accession>
    <name>E3QII1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cell morphogenesis protein PAG1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_05735</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094611.1">
        <property type="nucleotide sequence ID" value="XM_008096420.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QII1"/>
    <dbReference type="GeneID" id="24411100"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05735"/>
    <dbReference type="eggNOG" id="KOG1825">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000325_1_0_1"/>
    <dbReference type="OrthoDB" id="6287725at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030427">
        <property type="term" value="C:site of polarized growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025614">
        <property type="entry name" value="Cell_morpho_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025481">
        <property type="entry name" value="Cell_Morphogen_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039867">
        <property type="entry name" value="Furry/Tao3/Mor2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029473">
        <property type="entry name" value="MOR2-PAG1_mid"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12295">
        <property type="entry name" value="FURRY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12295:SF30">
        <property type="entry name" value="PROTEIN FURRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14225">
        <property type="entry name" value="MOR2-PAG1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14228">
        <property type="entry name" value="MOR2-PAG1_mid"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14222">
        <property type="entry name" value="MOR2-PAG1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cell morphogenesis protein N-terminal" evidence="2">
        <location>
            <begin position="217"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="domain" description="Cell morphogenesis central region" evidence="4">
        <location>
            <begin position="840"/>
            <end position="1316"/>
        </location>
    </feature>
    <feature type="domain" description="Cell morphogenesis central region" evidence="4">
        <location>
            <begin position="1319"/>
            <end position="1552"/>
        </location>
    </feature>
    <feature type="domain" description="Cell morphogenesis central region" evidence="4">
        <location>
            <begin position="1623"/>
            <end position="1788"/>
        </location>
    </feature>
    <feature type="domain" description="Cell morphogenesis protein C-terminal" evidence="3">
        <location>
            <begin position="1839"/>
            <end position="2090"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="578"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2215"/>
            <end position="2293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2366"/>
            <end position="2390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="581"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2255"/>
            <end position="2266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ30591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="2390" mass="268938" checksum="BC6624636810101F" modified="2011-01-11" version="1">MHAVGRMEPDAPPGPRSGTALSGTTLNSGHQVPERTSSATDFTNSSLSQTQRKLERMHSKSRREHTHHHSHSSKHHRDEQKTVGEYALHVLFTSFIAQAEEKLNDCITVPFEPEPQVEQICGPGVDPSFDQIITALGHIARPRPKPLIDSMMLWRKSKSDAANEARSQLQQSKGAAPVLLQRRNTEPVQPLPGAMDNGLASPQTSLAAKQEFVAHAERRSTVSIYILCRVLLEVISQTSLPFLTLEMEEKLEGIIFGQLKIADTDQLMVSPLKLANWNLFSQLLGAMSEINFRGVTDRFLGDLERSLQELVAKSPTSPAGRDAEGKIELVLGGMKHLKVNMSHPEAWEQSCDFMVAVGRLFHRSHGQRVKTAFCQVLETLLLTVAAQATNQDLAHPKWIEVLGSIGPRLAQMFIKPRHWGFAFPLTATLLCVSPPDTFGSQWLQLILPLQPKLKDRFTRPLCLQVIARLLWTYLYRTNDTLPNTTRKLDEVMKLVLPPTKRSLIASDSAVAEPIIQIIRIIGYKHPEYCFKHVIFPLINAELFVSNKDLRVEQLDPDRMVIGIRAFLAIMLDLERGDEGRPPFPSSFPPPPTIERERMPPSPMMVSPHHGSPMAFTGASGEGEQLSRPVRTSALNDVVKEYYHKFCEILGKITIICDNTFGGQAVLDEKFSSPGPKTPIADTFNFARRDDQPPADHKQAFYELLHVAVQALPRCLSADIPFNSLINLLCTGTAHVQYNIAYSSAQSLKAIARQAHAQQVTMGFARFIFNFDDRYSTMSDGGMLGPGHIESTLRLYVELLQIWIEEIRRKTRDASLDQLETSDKRGAKLDLSGIWAEVDQAEAHGLFFLCSQSRRVRYFAITVLRLITDFDRALQNQDRETLRVIDILENDSMQVMNFKDEGLSVAERSRLQRGMQNSNNRGALVELCTSDVSYDTTLWFKLFPNLIRIAYEKCPFTVTIGRDLICNRILQMYKAIVLLSEPSRGLYYGSDPGSARVAGRTPTTQPEILVEQWKFYLIFACTTLADPGSVVPANPQGTQHSRRTSKPASADKIVSARVLFKYLIPLLSVSSASVRDAVVSAMGSINIHIYRTLLEELAGQVSRCNDEARARIHQRTNSSPRRNRKMDLLRTEITHVYKLTCHFLKEEEVYNDEWVLTNLVTFTRDLKLFLMDGEVQMDWEFQKLRRHYCGLTEELFEGINRTKDPSRWMTFESRKSAFSLMEDWCGFSPNQTQIRVREDTMRQSLIDQQSLGERGTVTAAMEIEKRNLRTAALSAMAALCGGPMSITTESGATLQFDIRRMLAWIEAIFNSGSDRMNVIGRRALKNLIIHNQELPYLLEHCIARCYLSDVSKVQESYFAVVTQVLLEHLDYSCQFWKLLGLCLFTLGNDESEIRSKSARLMRSLEERQQPGRTSKIQDYDISISDKTKAVYKLAQFEISKRLAKQHTELAFHIFSEFTLYFKDLQPASQRNVVAVILPWIQSIELKVDPNGGPTSQSYVLLANLLEITIKSSGALHNEVQALWQALATGPYPGNVRLILDFIISLCLERREQNFVEYAKQIVVFLSSTSSTPGMKVVEFLLMQITPKAMVPNEKKDAMPPPPDIGLLPYCADLGEALPVGTKQAGFSLGQLSLILLVDLMVSPVHLTPENVPVLLQVVTVLWDHYTPLVQEQAREMLVHLIHELVISRLDDQTETTARASIEDLIDLIRRHDRSVVWGYEDSNGKADDHDNKVPPSMEFLTAEVVKTFEMTYPGIKDQWGRLSLTWATSCPVRHLACRSFQIFRCILTSLDQFMLGDMLARLSNTIADEDTEIQTFAMEILTTLKTLILKLDADKLLTFPQLFWTTCACLESINEREFLEAVEMLNEFLTKIDFRSLNVRRLLLDGQPSRWDGQFEGLQSLLYKGMRSSVCMEATLSTLDKLVQLPSDGLIGDDSRLFFAVLANFPRFLHEMEQDEPSEQALQSASILGAVCEVQGFRNIAELLGEYVTFKYQGNSREFQSRLFAALKDHFLPKLDFKMIIFLMGLLTNATAWVKLKTMRILSIVIPEIDMRRPDLAGHGSDLISPLLRLLQTEFCMEALEVLDNIMTMSGSAMDKQHLRMSMTRSTSKTIRKEYERTQSLFGIPEATGWAIPIPAKKTDSTRANIHAAFYMCQTAEGILTEATPTPDVEFHNDDFPYSYFQMPDRTETMMSDEGRADGHLSDLVTKLDSLDDFFDDLGTSPPSDDRSSKTITEFSPDSFESGAQLDPSSNTMNPGAFSAASSSSATGGMGGGSRPGLHYRSITSPSAPASYQPHISEFASDDEFLEDVFSDADDERPNTGNGEGSFSLESMIKPLAQSTRSRMRRLTGGRSRDNDRQQELFRAERAAAAHQVPKVPTNFLTKMPSQGEML</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIQ6</accession>
    <name>E3QIQ6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ATP synthase F0</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05888</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094764.1">
        <property type="nucleotide sequence ID" value="XM_008096573.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIQ6"/>
    <dbReference type="STRING" id="645133.E3QIQ6"/>
    <dbReference type="GeneID" id="24411253"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05888"/>
    <dbReference type="eggNOG" id="ENOG502S0ZE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024263_0_1_1"/>
    <dbReference type="OrthoDB" id="3357002at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021460">
        <property type="entry name" value="DUF3112"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35184:SF1">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35184">
        <property type="entry name" value="YALI0C10208P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11309">
        <property type="entry name" value="DUF3112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="260"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="327" mass="36123" checksum="47F53410E83C6B69" modified="2011-01-11" version="1" fragment="single">MAAVVPVEYPQPVYDYGPPYVPQVAALGLVPTISIDVPVCIILIILFVAAAGINLFILVRNLGCSHKFLFSGVLVGFCLTRIIALSLRIASATQPWNVRLNIAGSIFASAGIVLLYAITLIFAHRLLCGLHPNIGWIPAVVYFFYFCYFLLLVSLICAISAFIASFYTLVPKELHDCHLVQLFASTVFAIIALLPIPIVLFAAFYPGLRCPEPFGYGSLTAKIVIVLTAATLLAIGAVYICAANYAVRPVWFPGWWHYKVCYYIFLYALELVVVLLYAFSRFDLRFHIPDGACKAGDFIKGQHAYKRVSGLTFRASLDERITVHVDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIW7</accession>
    <name>E3QIW7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_05949</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094825.1">
        <property type="nucleotide sequence ID" value="XM_008096634.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIW7"/>
    <dbReference type="STRING" id="645133.E3QIW7"/>
    <dbReference type="GeneID" id="24411314"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05949"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_5_7_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ30805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="112" mass="12700" checksum="715863EA17BE7DF8" modified="2011-01-11" version="1">MNVTDAVLGGYKIPAGTVIYVLANAINRLSMYCGDRADELDPDRWDDLLATANPNAFMTFLQGLRGCVGRKFAETEMKILLCCLLSMCKFQRDSDTPDPEVWKMWRLVLRPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJ31</accession>
    <name>E3QJ31_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fructose-bisphosphate aldolase</fullName>
            <shortName evidence="3">FBP aldolase</shortName>
            <ecNumber evidence="3">4.1.2.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_06013</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:14729"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="2 3">Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class II fructose-bisphosphate aldolase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.13" evidence="3"/>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094889.1">
        <property type="nucleotide sequence ID" value="XM_008096698.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJ31"/>
    <dbReference type="STRING" id="645133.E3QJ31"/>
    <dbReference type="GeneID" id="24411378"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06013"/>
    <dbReference type="eggNOG" id="KOG4153">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040088_4_0_1"/>
    <dbReference type="OrthoDB" id="2558351at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00183"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004332">
        <property type="term" value="F:fructose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00947">
        <property type="entry name" value="TBP_aldolase_IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050246">
        <property type="entry name" value="Class_II_FBP_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000771">
        <property type="entry name" value="FBA_II"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30304">
        <property type="entry name" value="D-TAGATOSE-1,6-BISPHOSPHATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30304:SF0">
        <property type="entry name" value="D-TAGATOSE-1,6-BISPHOSPHATE ALDOLASE SUBUNIT GATY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01116">
        <property type="entry name" value="F_bP_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001359">
        <property type="entry name" value="F_bP_aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ30869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="288" mass="31697" checksum="92899BAEB72178B7" modified="2011-01-11" version="1">MTSWSEKKSRNRTLQILQTATEGKYGVLGAVAYNIEHLTAYVRAAEAKKSPMLILLFPSTVKQLPTLPWAVAAAIKSAKVPIALHLDHAQDEEDIREIAATMPFDSIMVDMSHYDHEENLAKTKVLTRVCHDHGIAVEAESGRINGGEDGIADTGDLEALFTTPEEVEDFIGAEIDLLAPSIGNIHGGYGPKGPELDYERLVNINKQVNSRVLMALHGTNGFSADIMKRCIDNGAIKLNVNKLLLEVWNTHLQENVNKPFSQLMEDGMNILQEEVERWIDICGSAGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJE9</accession>
    <name>E3QJE9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">JmjC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_06131</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ30987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095007.1">
        <property type="nucleotide sequence ID" value="XM_008096816.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJE9"/>
    <dbReference type="STRING" id="645133.E3QJE9"/>
    <dbReference type="GeneID" id="24411496"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06131"/>
    <dbReference type="eggNOG" id="KOG2132">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016785_0_0_1"/>
    <dbReference type="OrthoDB" id="47172at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461:SF101">
        <property type="entry name" value="TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="2">
        <location>
            <begin position="360"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="450"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="456"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="475"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ30987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="577" mass="62833" checksum="A7893126803692FA" modified="2011-01-11" version="1">MATGSHSPSEQDAGMSRVTGEAPRPPSNKMPGLDDPAFTEKCIRATASIHTDAHHHLNALAGNLVQRQSPEDENYGLKPLGPEVLKSLEDLALDVLTVHASEDAPPPQDGVRLLRRLDEEIERTYRRFYDFVYADLPYCWRQLYTDLSLLKFSCLVFLREWQKTAGGGGEVDGDKQLLDELIAVLDRALVLAGGAGVARGRKTISELLACLEDDCKLAPGPRPCLPAAFPTSRPFTPPVTRPIRVVDGMSMAAFQSYLDSPPSVDLGPEPLVLTSLLTGWPALSTRPWSSPGYLLSRTHAGRRLVPVEVGRSYVDEGWTQELVPFRELLSRIVAPSSSGSPAPSPAQDEAAADGRAAGTTYLAQHELFSQLPHLRNDILTPDHCFTAPPPHPLGPSADKPELELPLVNAWLGPAGTITPLHTDGYHNLLCQVVGAKYVRLYAPRDSEALCPRGVVDNDDDDDDDNAVAEEEGEGPGEHGVKGDGEGEGTRRKVDMSNTSAFDVGAVEGWDPDPEGRDAIELEEFRGLRHWDCVLEAGDVLYIPIGWWHYVRSLSVSFSVSFWWNGDHYVGPDGPSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJK0</accession>
    <name>E3QJK0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sister chromatid cohesion protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_06182</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the SCC2/Nipped-B family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ31038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095058.1">
        <property type="nucleotide sequence ID" value="XM_008096867.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QJK0"/>
    <dbReference type="GeneID" id="24411547"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06182"/>
    <dbReference type="eggNOG" id="KOG1020">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000901_0_0_1"/>
    <dbReference type="OrthoDB" id="418242at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090694">
        <property type="term" value="C:Scc2-Scc4 cohesin loading complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061775">
        <property type="term" value="F:cohesin loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140588">
        <property type="term" value="P:chromatin looping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034087">
        <property type="term" value="P:establishment of mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071169">
        <property type="term" value="P:establishment of protein localization to chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990414">
        <property type="term" value="P:replication-born double-strand break repair via sister chromatid exchange"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23958">
        <property type="entry name" value="SCC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000494">
        <property type="entry name" value="Sister chromatid cohesion protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024986">
        <property type="entry name" value="Nipped-B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033031">
        <property type="entry name" value="Scc2/Nipped-B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21704:SF18">
        <property type="entry name" value="NIPPED-B-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21704">
        <property type="entry name" value="NIPPED-B-LIKE PROTEIN DELANGIN SCC2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12830">
        <property type="entry name" value="Nipped-B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20168">
        <property type="entry name" value="PDS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Sister chromatid cohesion C-terminal" evidence="4">
        <location>
            <begin position="1469"/>
            <end position="1654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="158"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1794"/>
            <end position="1873"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="346"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="170"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1796"/>
            <end position="1816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1822"/>
            <end position="1852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1858"/>
            <end position="1873"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU364107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ31038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1873" mass="207947" checksum="1039745B594C673D" modified="2011-01-11" version="1">MVNSQGAIQNGPPNGGYMQPPAADQRPMARPFTLPEALPYSPQTSVIPFTSDLIPDPTLGSGSLASSISHMFNSQEYDSLNKEATGPNHNHGLKHLKYAVDHVLHDLKPNQRTYFKFKAVPKPNANMTSSPAGPQSLSAGLSPVAKMVFDRAPTFIKPSTGTPGLAPVNGQVTQQPLQHPSTPKATLPPKQSSTSAGTHQGNNFRFEVAIPSKKFDPKAYVEVPDQPAPLPVTVNPSEVTRVATSTQIIPKQETLVQPPHPVQFAPTQSGSTQTTPTEHVPMQLPKQGTPGRSDAQKTSFAIELPRAPEFNKDEYVEMALSDYPDEPTGLSMRRQDGAYQSRQDDISTNLNQRQRAEAALQDLERLIKSVFDAIRHVLGNEPGYEQVATLNSDNEAILTGSTQQKLQTAIAKAIDLGSYDQAPIEDLQYMQKLSEAGLMHTLNLDFRVEESWGESDVAGWLNQLPEIEMGLKTARTCLRIMCGGREEKQIYSEEVIQKCTDVFKGVVEGIVIPVVEMRGSGSSSTLFKLLQPHKKAIGPILTNCQKLFALLAKLVTSIELSDTALGTLEFAASSLLFVDNAYLEKDSVVGIQKFDGIRLTAMEMLCQIFLAKPEQRRGIFDDILTSLEKLPVGKQSARQFRLSDGGSIQPVSALIMRLVQASSGKVDEKGTRSRLAMMADEDADGDEEMTQPGKQAVAATIKSEEAGASQYNLALEELKSVALPLTEGSIHNANYVVTFMVNRALKSTKSGDTPYRNLLDLFVEDFTECLDSPDWPSAELILRQMTFYMMKLWEGDRTAAPAKNMALELLGVMSAAVSKLRSHVRKITYTMDSSDSNELSRYLSELATAALEQKIRVEHDVSWSGPYRTTLEHLQRRSGDDPHLQGAISFLIADWAQRIFSGYDAMQETYDSLDQEFGRLAFRLRMMIEDRRWLSNEYTFKDVTNKHAKLAYSIILLRSPFCEHFKAMLNVLLTAMASDQATVRSKSLKSINQLLETDPAILDGDSVVVHLIINCSSDSSPQVRDSAIGLMGKCIGLRPRLEDKMAERIIERFIDSGIGVRKRAMKLARDIYLRNQSREIRSNIANGLLHRVQDPDEGVRELARQMIEEVWFAPFYQVDDTAAFKTSLTDHVALMIQTVKSGNVGAVLDKVLQSILGGGQNKAQTGPFGVSMQLVEKMFELIDNLDSDDPTIPPGRDALQVLQIFAKADPKLFTFEEIRLLKPHLSSISGADDLAVFKAVTVIYRQVLPQLSSKYADFLREVREQLQNSVGRLNKNLLDDVVACLWIIADLLDNRDKLAYLGASSLRGVASMRNTQMDATKLMKFARYSTIVGMVGKHCDLDSEIDVFKKIFPKYSGTSVAKLMVDNLSPWADESQVMEARKHALDAIGLICQAHPRNYVSPNVYTKFQQVFEARIPALESTILRSFKEFLITEEKRSEAATAAATTGSEGDKKRELTVMGGTNYDDVASATTQRFLKEITRIALSSQDEHAFLAVEVLGSINRQGLVHPKETGVTLITLETSSMTKISEVAFMEHRALHEKHETVIEREYVRAIQAAYEYQRDIVKDTRGATTNPFQSKLHLLMEVLKVSKSKNRQRLLEKLVFQVDFDPSKLDVSTPLPPHVEYARFMIENLAYFDYVTVGEVLVTVNAMEKLFSTTGSSMAHVIESEIFNVRMDMDKPDDLQGDGQPTQPHLTVPPKRLRQLTSGSIILLCLWEARTYLRRLYGLGSKRETKTKLAAKDLSKAPTKVQGVTGDKFWEEVNSHMNGLTSQEATLAKCKAFVELMNVDKEFKVADEDELDGEDAGTPSDDEDDGPAADGRGRKRKAGVLPGNRKKRARSTSRPRPRGRPRKNVVPTEAEDDADGDFDDMDFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QL60</accession>
    <name>E3QL60_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Isopenicillin N synthase-like Fe(2+) 2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_06887</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697356">
        <property type="protein sequence ID" value="EFQ31598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095618.1">
        <property type="nucleotide sequence ID" value="XM_008097427.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QL60"/>
    <dbReference type="STRING" id="645133.E3QL60"/>
    <dbReference type="GeneID" id="24412252"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06887"/>
    <dbReference type="eggNOG" id="ENOG502QR0G">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047601_0_0_1"/>
    <dbReference type="OrthoDB" id="10248513at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.330:FF:000039">
        <property type="entry name" value="Unplaced genomic scaffold supercont1.13, whole genome shotgun sequence"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isopenicillin N synthase-like Fe(2+) 2OG dioxygenase" evidence="2">
        <location>
            <begin position="225"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ31598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="372" mass="41496" checksum="728B98B8E05906AE" modified="2011-01-11" version="1">MAAAQDVPMDLPIIDLDVFLNEPRDSPAVRDECAKAATALITYGALVLHDSRVAESDNTTFLDLLEDYFALPTEELKKDERPELSYQIGVTLENTEKPKCAVDEPCLQVIERLAPSERPLDIGGHQPDPKCRFFWRMGENPPYETEFPGLNAPNVIPEAPHIRERWPSAMDKWGTSMKQAVTGLAEMAAVGLGLPADTFSNAAKYGPHLLAPTASDLVKYGKQDTILAGFHTDLNFLTIHGRSRYPGLHIWARNTGKKISVKIPEGNYLLVQAGKQLEHFTGGLIKAGFHEVVVNEKTLDVIERRKTQFPDRPLVRISSTFFYHLSSDHDITPIPQLAEQAQKFRAEQFNLGKDEGEEAVYPPMKVGQQVQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLE3</accession>
    <name>E3QLE3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_06656</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697357">
        <property type="protein sequence ID" value="EFQ31681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095701.1">
        <property type="nucleotide sequence ID" value="XM_008097510.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLE3"/>
    <dbReference type="STRING" id="645133.E3QLE3"/>
    <dbReference type="GeneID" id="24412021"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06656"/>
    <dbReference type="HOGENOM" id="CLU_2183752_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ31681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="109" mass="12138" checksum="1B0DF7C0B85D2081" modified="2011-01-11" version="1">MDLARWCSRLTLELLTSIELILVAEKLILKLSNSIELILVAEKLIVKLSNSIELILVAEKLILKLSNSIELILVAEKLILKLSNSIELILVAEKLILKLSNSIELILVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLR2</accession>
    <name>E3QLR2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_06775</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697357">
        <property type="protein sequence ID" value="EFQ31800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095820.1">
        <property type="nucleotide sequence ID" value="XM_008097629.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLR2"/>
    <dbReference type="GeneID" id="24412140"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06775"/>
    <dbReference type="eggNOG" id="ENOG502SSTB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_150197_1_0_1"/>
    <dbReference type="OrthoDB" id="4083871at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42077">
        <property type="entry name" value="YALI0F30239P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42077:SF1">
        <property type="entry name" value="YALI0F30239P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="103" mass="11448" checksum="979849D8CFBE0AC5" modified="2011-01-11" version="1">MAWGKKAHPPPPSTISQVLPLIITVVFLAGVAWVLWQVYISVTKIQESASERMGKKNVVFTKDGVRVGVRHTSTENYVDQTQSWVVKAWNLSGNTVGQIKKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMU1</accession>
    <name>E3QMU1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_07323</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="GG697360">
        <property type="protein sequence ID" value="EFQ32179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096199.1">
        <property type="nucleotide sequence ID" value="XM_008098008.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QMU1"/>
    <dbReference type="GeneID" id="24412688"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07323"/>
    <dbReference type="eggNOG" id="KOG0519">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000263_0_0_1"/>
    <dbReference type="OrthoDB" id="303614at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009927">
        <property type="term" value="F:histidine phosphotransfer kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16922">
        <property type="entry name" value="HATPase_EvgS-ArcB-TorS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.130:FF:000050">
        <property type="entry name" value="Related to histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000010">
        <property type="entry name" value="Sensor histidine kinase RcsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2300:FF:000158">
        <property type="entry name" value="Sensor histidine kinase/response regulator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047:SF74">
        <property type="entry name" value="HISTIDINE KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047">
        <property type="entry name" value="TWO-COMPONENT HISTIDINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAC" evidence="11">
        <location>
            <begin position="1061"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="10">
        <location>
            <begin position="1120"/>
            <end position="1175"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="11">
        <location>
            <begin position="1270"/>
            <end position="1324"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="1335"/>
            <end position="1561"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="9">
        <location>
            <begin position="1868"/>
            <end position="1990"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="318"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="495"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="653"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="781"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="955"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1583"/>
            <end position="1643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1667"/>
            <end position="1692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="71"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="140"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="359"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="391"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="781"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="817"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="854"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="956"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1595"/>
            <end position="1606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1620"/>
            <end position="1633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1634"/>
            <end position="1643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1670"/>
            <end position="1684"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="1920"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ32179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1990" mass="218041" checksum="7F3488572E3B300D" modified="2011-01-11" version="1">MSDASKEQSSSQSQADRSKAQAEPSATKPATSSPDTNLKSSVDASQTYNDVGGLGGKEEKSREDEAAGTTAAPSQPAPSESQIQLNRYRERLARDLERREMVTRGLTATTPEKMRVSPILEESGNSPRSNIAAMSTSLSNLTTTSTESGNTVRGGMAPGNVAGTPSYPFPRMHTPGYGPSSMNRAFGNMSPTAAAFMSQTMSFEGFGSAQDRVLSGSSTPASALTFLPAGATGQLEGDFPSPNLYDLSLMLTAEPGLDAWWNTVVQIMRDVYKAERVTLAVPADSTDIENVPWGQKATYNEHQEDELSLGYMARGSSLIPSSAGDVGSEETPSASEDPARPRLLSRPSLQTRHSFTAYEDNRERKGNNDRLLPSRRPTQLGRSKSYFPPGQASQEDAEASQQNVEAPGPVLNKSALAEHDAEEQNIPSWEAPLANTNTAGRVLPVLQALDYEADPLIHHSGVMRVLERGKVIALTRSYPYLQNLPEEMHIKSKVTANTTSAEAARKKLRKGRIESSSKLSSILGGANSSFGSNRSHSSDKPSSMISRLDDGEPRPPTPKYEEFEQAPPSPWSQSPAPSPAVRADPTENPFFTDAMVDEDSFNPDSAPTDYTGMRPPEAIGVDNSWTVLHIPLTHVLLSKPARPFKLNNSILEQKSHSRSWNEAPEPSADEDDAEASWQRKDRPAPIAILSILSPIIPYPSNLRHSLEYLAPHLATSFSLCRHYTNLETELTGLHRRRPHTAGFGALAADGRPLADPASIGNLSFMPSDDIAAQRSLAGSITSPSDYSGISKSATGSPIGTPGWDQSSLHQLIDKRGSATSPAQTSGDGYFNTKQKSAASRVESSTNSQTTRRGSKGESPVDKRQAPLSATHRPRIQETSQPLGESPEVAEKNTESRASTPGGAKRVLSHELKNYLDEIAVLEPRLKPVEHKGGDHSHHTLLHSYGADFATSFQSLPPSSSVVSRPVPHTAPSRTGSLSQGPVDMPPPSDRLKGLILDSLPAHVFVSLPQTGEIVWVNSRYLTYRGQTVSDLAADPWGSIHPDDRDEYLKAWSHSLRTGEQFSRTVRIRRFDGAYRWFYARAVASRDKRGVMMQFLGSYMDIHDQHIAELKAARQEEIEASEAKHRLLANLIPQIIFTATEDEGITFANEQWLSYTGQSFEDSLGLGFMDFVHPDDLAKCQIPTDRPPTPMPSKFDRKGHQELSEAMPTSVVSSKVQSQLETNLRGIHQALSRNNSSSSSSVYEMPTADITVLARQGVIKVTTDSNGRLSYTTEVRLRSKNGEYRWHLIRCVEIDNIDFGNGASSYFGSATDINDHKLLEAKLKEAMESKSRFLSNMSHEIRTPLIGISGMVSFLQDTVLNEEQRDYTNTIQTSANSLLMIINDILDLSKVDAGMMKLKYEWFHTRSLIEDVNELVSTMAIAKRLELNYIVEEDVPAWVKGDKVRIRQVLLNVIGNAIKFTTEGEVFSRCRVYKDGASSNLDNEIVLEFAIIDTGRGFTKEEADLIFKPFSQIDGSSTRQHGGSGLGLVISRQLVELHGGKMEGSAVPGKGSTFTFTAKFALPTKEDHPDAPLSPETLDTPAETAQELSVHRPAKTLQSPRAASTISPRAEPGFVSPALASSGSSDPSVRSSISQTTERTSVSSVNVGLVHFSEAARASGQDLSQMKLELPSGESSPGTTPTPETAKPGKTEDLKPPMYSILIICPQTHSREATAQHIEMTLPKDVPHQITALDSTEKAQRLLGEGDSVNFTHIVINLPSPEEIIGLMEQIIRSTTIRDTTILILSDSVQRQAVMRLATDTEYERLVSENIVTFIYKPVKPSRFAVIFDPDKVRDLSIDRNRSTAQRMVETQKASYQEIGKRMGNKGYKVLLVEDNPVNQKVLQKYLKKVGVDVEVAADGVECTDMVLARSHNYYSLILCDLHMPRKDGYQACREIRQWERERGFKKLPIIALSANVMSDVHDKCVAAGFSDYVTKPVDFIDLSRAMSKFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNI5</accession>
    <name>E3QNI5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">xylan 1,4-beta-xylosidase</fullName>
            <ecNumber evidence="11">3.2.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_07742</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>Hydrolysis of (1-&gt;4)-beta-D-xylans, to remove successive D-xylose residues from the non-reducing termini.</text>
            <dbReference type="EC" id="3.2.1.37"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Glycan degradation; xylan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.37" evidence="11"/>
    <dbReference type="EMBL" id="GG697362">
        <property type="protein sequence ID" value="EFQ32472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096492.1">
        <property type="nucleotide sequence ID" value="XM_008098301.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNI5"/>
    <dbReference type="STRING" id="645133.E3QNI5"/>
    <dbReference type="GeneID" id="24413107"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07742"/>
    <dbReference type="eggNOG" id="ENOG502SHDC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004542_5_3_1"/>
    <dbReference type="OrthoDB" id="47059at2759"/>
    <dbReference type="UniPathway" id="UPA00114"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046556">
        <property type="term" value="F:alpha-L-arabinofuranosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009044">
        <property type="term" value="F:xylan 1,4-beta-xylosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031222">
        <property type="term" value="P:arabinan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044993">
        <property type="entry name" value="BXL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42721:SF3">
        <property type="entry name" value="BETA-D-XYLOSIDASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42721">
        <property type="entry name" value="SUGAR HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180611" description="xylan 1,4-beta-xylosidase" evidence="12">
        <location>
            <begin position="19"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type III-like" evidence="13">
        <location>
            <begin position="674"/>
            <end position="744"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00026107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ32472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="767" mass="83779" checksum="C9D15A59917CC3A3" modified="2011-01-11" version="1">MKSTWLIVLGAVVSVVTQEEDPESRRQSYPNCVNGTLSVNKVCDRTLSPPERAAALVKALTVEEKLQNLVSKAQGAPRIGLPAYNWWSEALHGVAYAPGTYFPEGDVEFNSSTSYPMPLLMAAAFDDELIEQIGAAIGIEARAWGNAGWAGLDYWTPNVNPFKDPRWGRGSETPGEDVLRVKRYAEYITRGLDGPVPGEQRRVISTCKHYAGNDFEDWNGTSRHDFDAKITAQDLAEYYLMPFQQCARDSKVGSIMCAYNAVNGVPSCANEYLLQNILREHWNWTEHNNYVTSDCEAVLDVSANHKYAPTNAAGTAICFEAGMDTSCEYTGSSDIPGAWSQGLLKEETVDRALLRLYEGLVRAGYFDGHEAIYAKLGWKDVNSAEAQSLALQAAVEGIVLLKNNGTLPLDLKPSHKVAMIGFWADAPDKLQGGYSGRAAHLHTPAYAARQLGLDITLASGPVLQRNNASDNWTAAALEAAEGADYILYFGGLDTSAAGETLDRTDLEWPEAQLMLIKKLSALGKPLVVNLLGDQLDDTPLLQLDEVSSILWANWPGQDGGVAIMKLITGEKSPAGRLPVTQYPSNYTDLIPMTSMDLRPTSQYPGRTYRWYDKPIKRFGFGLHYTTFKAEVGGAFPKTLRIADLVGCGNEHPDTCPAPPLPVSITNTGNRTSDYVALAYLSGEYGPRPYPIKTLSAYKRLRDVAPGETATVDLAWTLGDIARHDEQGNTVLYPGEYTITIDEPTLATAAFTLEGEEAVLDKWPAPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNP8</accession>
    <name>E3QNP8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_07675</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697362">
        <property type="protein sequence ID" value="EFQ32405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096425.1">
        <property type="nucleotide sequence ID" value="XM_008098234.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNP8"/>
    <dbReference type="STRING" id="645133.E3QNP8"/>
    <dbReference type="GeneID" id="24413040"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07675"/>
    <dbReference type="eggNOG" id="ENOG502SHZD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_24_0_1"/>
    <dbReference type="OrthoDB" id="5417887at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF42">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="3"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ32405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="130" mass="14524" checksum="DC09272EFDA16E36" modified="2011-01-11" version="1">MSINLGFGRHYYDTKPQSNLLTIALYTSVGASICCFASTGSKVGFGVTLLRLPSGWYKAFVWFAVVTLTAVMLPSATMTWLECHPMQKDFNSQMEGTCWDKSVTLNYGIFNVAWCAFTNFILALIPWNLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNW8</accession>
    <name>E3QNW8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Beta-1,3-glucan-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_07570</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697363">
        <property type="protein sequence ID" value="EFQ32556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096576.1">
        <property type="nucleotide sequence ID" value="XM_008098385.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNW8"/>
    <dbReference type="SMR" id="E3QNW8"/>
    <dbReference type="STRING" id="645133.E3QNW8"/>
    <dbReference type="GeneID" id="24412935"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07570"/>
    <dbReference type="eggNOG" id="ENOG502QRX5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019533_1_2_1"/>
    <dbReference type="OrthoDB" id="4781at2759"/>
    <dbReference type="PHI-base" id="PHI:6228"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.200:FF:000178">
        <property type="entry name" value="Glycoside hydrolase family 16 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF62">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="3">
        <location>
            <begin position="125"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ32556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="477" mass="53065" checksum="8C8BF2E5005BA52F" modified="2011-01-11" version="1">MDQDQGYYSRSAAAGTPLRPSTPNTESSRNPFGDGIESQAASQRGPVTTNPFGTPAVSRPASSFGSASALGARFDERTNRYFHSRRIRKEDIEKPWLNKADPKEKWVTIIPIIGILVGLVVSGFLIWDGVRSVVKHKYCPVLIEDFSSGALDTNVWTHEVQVGGFGNGEFEMTTADNENVFIKDGNLVILPTLTDSALIEKDNVIDLLKDGTCTSDQPSACIAATNTTAGNSSIVPPTRSGRINTKKGATLKYGRVEVVAKLPKGDWLWPAIWMMPVQDTYGAWPLSGEIDILESRGNNWTYAQGGNNIASSALHWGPDHANDAWWRTNNKRQALHTTYADGFNTFGLEWSQKYIFTYINSRLLQVLYTNFDEPMWQRGDFPQANSNGTRLEDVWSQTGRSNTPFDQKFYLIINVAVGGTNGWFQDGQSGKPWLDSSPNAKKDFWNARDQWLPTWTSPELSVSKVSMWQQCDGDEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QP60</accession>
    <name>E3QP60_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_07662</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697363">
        <property type="protein sequence ID" value="EFQ32648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096668.1">
        <property type="nucleotide sequence ID" value="XM_008098477.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QP60"/>
    <dbReference type="GeneID" id="24413027"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07662"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_4_2_1"/>
    <dbReference type="OrthoDB" id="3639251at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000386">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000065">
        <property type="entry name" value="Putative MFS pantothenate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF39">
        <property type="entry name" value="TRANSPORTER LIZ1_SEO1, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="189"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="292"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="332"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="359"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="453"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="63"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="480"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ32648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="501" mass="55399" checksum="E1E0650E25128529" modified="2011-01-11" version="1">MGSEHEYASSSAKGGTMDDSLSDEHNSTAIAKKKAPWWAYIWDYEPDRSPEERAFIQKLDVFLITMLSFGYFIKNLDQTNISNAFVSGMKEDLHMNGNEINLIDTAWTVGYVVGQIPSQIVLTKVRPSIWVPSCELLWTVLTFCLAAAKTSNHVIAIRFFVGLAESIFYPAAHTILGSWYKPSELGKRACIFHASSAAASMFSGYLQAGVYRGLNGVHGLTGWKWLFIMDGVISLPICIAGFFFLPDLPENTRAFYLNENDRELARKRMASVGRAPRTKLGRSAFKRIFGRWHVYLLSILYIIFINIGPSSSVNPFSLWLKSRGESVEKINIIPTAASAVQLVLTVSFAIISDAIRHRASIMSISTFLGGFAALILAIWNVPDGLKWFAFLLQRASVPYGPLSMSWTNEICGADAEERAIVIGIMNSLGYAFNAWVPILTYPQVDAPTFKKGFIFSTAAFGAQAAITASVAYLYKRDKKKQGIAKRDEEGVTAPASVPDLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QP85</accession>
    <name>E3QP85_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Molybdopterin synthase catalytic subunit</fullName>
            <ecNumber evidence="4">2.8.1.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Common component for nitrate reductase and xanthine dehydrogenase protein H</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Molybdenum cofactor synthesis protein 2 large subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Molybdenum cofactor synthesis protein 2B</fullName>
            <shortName evidence="4">MOCS2B</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">cnxH</name>
        <name evidence="6" type="ORF">GLRG_07817</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>2 [molybdopterin-synthase sulfur-carrier protein]-C-terminal-Gly-aminoethanethioate + cyclic pyranopterin phosphate + H2O = molybdopterin + 2 [molybdopterin-synthase sulfur-carrier protein]-C-terminal Gly-Gly + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:26333"/>
            <dbReference type="Rhea" id="RHEA-COMP:12202"/>
            <dbReference type="Rhea" id="RHEA-COMP:19907"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58698"/>
            <dbReference type="ChEBI" id="CHEBI:59648"/>
            <dbReference type="ChEBI" id="CHEBI:90778"/>
            <dbReference type="ChEBI" id="CHEBI:232372"/>
            <dbReference type="EC" id="2.8.1.12"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the MoaE family. MOCS2B subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.12" evidence="4"/>
    <dbReference type="EMBL" id="GG697364">
        <property type="protein sequence ID" value="EFQ32673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096693.1">
        <property type="nucleotide sequence ID" value="XM_008098502.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QP85"/>
    <dbReference type="STRING" id="645133.E3QP85"/>
    <dbReference type="GeneID" id="24413182"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07817"/>
    <dbReference type="eggNOG" id="KOG3307">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089568_3_1_1"/>
    <dbReference type="OrthoDB" id="5531344at2759"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990140">
        <property type="term" value="C:molybdopterin synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030366">
        <property type="term" value="F:molybdopterin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00756">
        <property type="entry name" value="MoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1170.40:FF:000003">
        <property type="entry name" value="Molybdopterin converting factor subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.40">
        <property type="entry name" value="Molybdopterin biosynthesis MoaE subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03052">
        <property type="entry name" value="MOC2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036563">
        <property type="entry name" value="MoaE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028888">
        <property type="entry name" value="MOCS2B_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003448">
        <property type="entry name" value="Mopterin_biosynth_MoaE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23404">
        <property type="entry name" value="MOLYBDOPTERIN SYNTHASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02391">
        <property type="entry name" value="MoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54690">
        <property type="entry name" value="Molybdopterin synthase subunit MoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="152"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="114"/>
            <end position="115"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="137"/>
            <end position="139"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ32673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="176" mass="19068" checksum="0D570368FF11B662" modified="2011-01-11" version="1">MESQDRGPWEASEGSCYVALTYDVLDAASVMNRVRSPQAGAIVLFSGTTRDSFGDKPVKELQYSAYTPLALRTMLSIAKGVLERHGLKGAAMVHRLGTVPIGEESILIAVSSPHRQAAWRAGEEALEECKAKVEVWKREEFHGEEGVWRANRDGIAGQKVSDAEKEAGGPDAAMIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPW4</accession>
    <name>E3QPW4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08035</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697365">
        <property type="protein sequence ID" value="EFQ32891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096911.1">
        <property type="nucleotide sequence ID" value="XM_008098720.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPW4"/>
    <dbReference type="GeneID" id="24413400"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08035"/>
    <dbReference type="HOGENOM" id="CLU_3068567_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="53" mass="5839" checksum="6EB66F6B374633AD" modified="2011-01-11" version="1">MATGFNHDEQGGRRVEACSTASSPGNGPGEGAVRRRLRRCIPRLLARYQARRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPX6</accession>
    <name>E3QPX6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Autophagy-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_08058</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">Autophagosome membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Vacuole membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the ATG8 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697366">
        <property type="protein sequence ID" value="EFQ32914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096934.1">
        <property type="nucleotide sequence ID" value="XM_008098743.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPX6"/>
    <dbReference type="SMR" id="E3QPX6"/>
    <dbReference type="STRING" id="645133.E3QPX6"/>
    <dbReference type="GeneID" id="24413423"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08058"/>
    <dbReference type="eggNOG" id="KOG1654">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_119276_0_1_1"/>
    <dbReference type="OrthoDB" id="6738456at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000421">
        <property type="term" value="C:autophagosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048646">
        <property type="term" value="P:anatomical structure formation involved in morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16128">
        <property type="entry name" value="Ubl_ATG8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000010">
        <property type="entry name" value="Autophagy-related protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004241">
        <property type="entry name" value="Atg8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10969">
        <property type="entry name" value="MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02991">
        <property type="entry name" value="ATG8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0072">Autophagy</keyword>
    <keyword evidence="8" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="7 9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <feature type="lipid moiety-binding region" description="Phosphatidylserine amidated glycine; alternate" evidence="9">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR604241-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ32914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="121" mass="14041" checksum="C0609DBCE3AE1246" modified="2011-01-11" version="1">MRSKFKDEHPFEKRKAEAERIRQKYSDRIPVICEKVEKSDIATIDKKKYLVPADLTVGQFVYVIRKRIKLSPEKAIFIFVDEVLPPTAALMSSIYEEHKDEDGFLYITYSGENTFGGFETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQ16</accession>
    <name>E3QQ16_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">WD repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_08098</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat LST8 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697366">
        <property type="protein sequence ID" value="EFQ32954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096974.1">
        <property type="nucleotide sequence ID" value="XM_008098783.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQ16"/>
    <dbReference type="STRING" id="645133.E3QQ16"/>
    <dbReference type="GeneID" id="24413463"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08098"/>
    <dbReference type="eggNOG" id="ENOG502RZG9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004531_0_0_1"/>
    <dbReference type="OrthoDB" id="10248252at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031931">
        <property type="term" value="C:TORC1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031932">
        <property type="term" value="C:TORC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032956">
        <property type="term" value="P:regulation of actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031929">
        <property type="term" value="P:TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037588">
        <property type="entry name" value="MLST8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19842">
        <property type="entry name" value="G BETA-LIKE PROTEIN GBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19842:SF2">
        <property type="entry name" value="WD REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_5G04300)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="157"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="178"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="231"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ32954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1084" mass="120730" checksum="06422A6211E6B00A" modified="2011-01-11" version="1">MLALNGSPEKPANPPKTVIDLTSDELPVSIDLTTVDDSPPPSPRQTAVNSEPPRKRQRVSNGSFLSSKSRDLAACLKAQVKPYIDAALAEIPVDKANAYEIGTRVINDIGSTPQFSLEFTHKGGFLSLALERDLADKARDLVAHYYGHLQPVFGGPAGTQASPSLRAPSVSATAHAIPNTSPSKRTPVTSSRTLSIPRKSSTHPASASQTKPRPCAQDLPGPPVSPTNYRTKARAKSFKSWKTRTSQSARATARRRAKIAWMNMPRRPYITTEERNRIFRGTRKLIRTSATAVAHGPLPFHVDFTPDEMEALWRRIREGSGKKARTKRRSDTVRELGRLLRKKPELLTVIPPELELRGALAQRDRVAIRNLLDELLDRQKRPARQPKVLTLELDESDKQGEAQRTSQIPSLLFAREIDGHRGFGRMRRQVNFSNELRKAHEDHLELRAEWVGCAGDIMTIVWTSDTNFICGATAHSDSHNQQYNKAGNLLLCSTTRGQLKAYPDHRIPRPVVEKGENSTEAMRESQSPWLYSSVVSSDYDQINDRAYTSSFDKTVKVWRVDKTGGNMTVLGTWAHLGNVNFVAVSKHECGMVATAADVASHAVRVYNVDSNSISTSPYQTYSGSRAWNEGDEQTTGTQKWAYFPATMQWGLAPEVQHLLLVGYSPRSLTGDDNDIPDGKRNTGEICLWNCLTGDKIKVLTASTQNVFEVVWHPTLPSFLVATSPAGLMVDDHTMTQVRVFRPSQTPEGDTAFGEIQCLDCPARDINELTIKPNSVICSYVTAACTDGKVYVWDTARGDKPIHVLRHKKPIDEFSGDREEADVGVKFTAWGTTPDRFYTGGSDGVVKVWNVRNLRQPLVRDLLEAPGAISCGAFSPCFSRLAIGDATGRVMLLSLDEKDEPPAKYIMPPIPPGVRPRGAHPVRRPMPIIEHEEPPAPNSGAEPHTGVERGRMLLARGQLLRHRDPTIGVIQGPQYLDLGLYRSELHFEGNPSQPLLAKVEWEQQENQKMFRRKSLKVTRYRPLRDMPSVACQVQHAENMAKDIDLQELDEMTKQYLVVDDPIHDQGWEFDLEEEIDYEKSAWAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQ57</accession>
    <name>E3QQ57_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Beta-xylanase</fullName>
            <ecNumber evidence="6">3.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_08139</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-xylosidic linkages in xylans.</text>
            <dbReference type="EC" id="3.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the glycosyl hydrolase 10 (cellulase F) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.8" evidence="6"/>
    <dbReference type="EMBL" id="GG697366">
        <property type="protein sequence ID" value="EFQ32995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097015.1">
        <property type="nucleotide sequence ID" value="XM_008098824.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQ57"/>
    <dbReference type="SMR" id="E3QQ57"/>
    <dbReference type="STRING" id="645133.E3QQ57"/>
    <dbReference type="GeneID" id="24413504"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08139"/>
    <dbReference type="eggNOG" id="ENOG502QSCW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020161_5_0_1"/>
    <dbReference type="OrthoDB" id="3055998at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031176">
        <property type="term" value="F:endo-1,4-beta-xylanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044846">
        <property type="entry name" value="GH10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001000">
        <property type="entry name" value="GH10_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31490:SF76">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31490">
        <property type="entry name" value="GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00331">
        <property type="entry name" value="Glyco_hydro_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00134">
        <property type="entry name" value="GLHYDRLASE10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00633">
        <property type="entry name" value="Glyco_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51760">
        <property type="entry name" value="GH10_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012610020" description="Beta-xylanase" evidence="7">
        <location>
            <begin position="16"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="GH10" evidence="8">
        <location>
            <begin position="36"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ32995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="338" mass="37292" checksum="28AA99CF3D22D25D" modified="2011-01-11" version="1">MKFQLAFLFVPLAAALPTEFQSSNAELAARSALEDRQASISIDQRFKNRGKVYFGTATDRGLLQRERNAAIIRANFGQVTPENSMKWQSLQPNQGQYNWGDADYLVDFATQNGKSVRGHTLIWHAQLPTWVSNIRDANTLRNVIRTHVTTVVTRYRGRIRAWDVVNEIFNEDGTLRTSVFSTVLGEEFVKIAFQAARAADPNCKLYINDYNLDRAGVSKVNLMRYYVDKWISEGVPIDGIGTQTHLSAGAGSAVRGALDQLASARVTEIAITELDIANAPTADYNAVVSACLAVPKCVGITVWGVSDKDSWRTGANPLLFDGNFNPKAAYNSIIQLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQ76</accession>
    <name>E3QQ76_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08158</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697366">
        <property type="protein sequence ID" value="EFQ33014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097034.1">
        <property type="nucleotide sequence ID" value="XM_008098843.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQ76"/>
    <dbReference type="STRING" id="645133.E3QQ76"/>
    <dbReference type="GeneID" id="24413523"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08158"/>
    <dbReference type="eggNOG" id="ENOG502ST0H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054584_0_0_1"/>
    <dbReference type="OrthoDB" id="66964at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="315"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ33014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="346" mass="37510" checksum="A8F251417FDF3AD3" modified="2011-01-11" version="1">MLPPVEPSVLQNNPQFAELHHALTTAILNLDGTTRKPTTKEQTSAQNELADHRFNAAKEHLLISAISNTAPPEPKAVSVRIITRSKSASQPASAPQPQQLPDSLLDLLLLLPPLLTATTEPLPADALAILLSNPPFTEFQALLPQLGELVSATLHASAVALARIANPTTNPSFLHRNVPALQTTYHRLEADVREAKHALARERVRVAGSLTGLLDKYAGALTLLVRALEAKHGVVARSLEFRAAEAGLEAQRAEADAVAAREGVRREVYSPEMAAALKNYSAHLRDARMRLEGTVATLRSELEGYGVAGGGDGGKERMLREMARKKRQLERELEDARRDVARLDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QR56</accession>
    <name>E3QR56_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zinc-finger domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08488</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697369">
        <property type="protein sequence ID" value="EFQ33344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097364.1">
        <property type="nucleotide sequence ID" value="XM_008099173.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QR56"/>
    <dbReference type="STRING" id="645133.E3QR56"/>
    <dbReference type="GeneID" id="24413853"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08488"/>
    <dbReference type="eggNOG" id="KOG3456">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083053_1_1_1"/>
    <dbReference type="OrthoDB" id="307899at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006120">
        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.40:FF:000003">
        <property type="entry name" value="NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.40">
        <property type="entry name" value="q5lls5 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019401">
        <property type="entry name" value="Znf_CHCC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13156:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13156">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 13 KD-A SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10276">
        <property type="entry name" value="zf-CHCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Zinc finger CHCC-type" evidence="1">
        <location>
            <begin position="112"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ33344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="167" mass="18441" checksum="9309FF8B9314D2CA" modified="2011-01-11" version="1">MLSASRRATSALSRQLRVASRPFSVSTTVRTTERPAVVEKNEAATPQVADNTVPATISQAPNRAVIWSRSQKPRAEAMTGPRFEQTDFSLQPQPYAAIELIHQEPVRWTHKRVVACDGGGGPAGHPRIFINTDKPEICTCNYCGLPFANEHHREHLESLPETSYPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRB0</accession>
    <name>E3QRB0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="19">Cytochrome b5-like Heme/Steroid binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">GLRG_08677</name>
    </gene>
    <organism evidence="20">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="14">Binds 2 Zn(2+) ions per subunit that likely form a catalytic dimetal center.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sterol desaturase family. SCS7 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697370">
        <property type="protein sequence ID" value="EFQ33398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097418.1">
        <property type="nucleotide sequence ID" value="XM_008099227.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRB0"/>
    <dbReference type="STRING" id="645133.E3QRB0"/>
    <dbReference type="GeneID" id="24414042"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08677"/>
    <dbReference type="eggNOG" id="KOG0539">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034756_0_1_1"/>
    <dbReference type="OrthoDB" id="2204368at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080132">
        <property type="term" value="F:fatty acid 2-hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014430">
        <property type="entry name" value="Scs7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12863:SF1">
        <property type="entry name" value="FATTY ACID 2-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12863">
        <property type="entry name" value="FATTY ACID HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005149">
        <property type="entry name" value="IPC-B_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="13" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="15" id="KW-0349">Heme</keyword>
    <keyword evidence="15" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8 14" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="256"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="310"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="18">
        <location>
            <begin position="6"/>
            <end position="85"/>
        </location>
    </feature>
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        <location>
            <begin position="95"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="101"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
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        <location>
            <position position="68"/>
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        <ligand>
            <name>heme</name>
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        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="273"/>
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        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
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        <location>
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            <label>1</label>
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            <position position="297"/>
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        <ligand>
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        <ligand>
            <name>Zn(2+)</name>
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            <name>Zn(2+)</name>
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        <location>
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            <name>Zn(2+)</name>
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        <ligand>
            <name>Zn(2+)</name>
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            <position position="380"/>
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        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005747"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
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            <dbReference type="ARBA" id="ARBA00022989"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
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    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
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    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR005149-1"/>
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    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR005149-50"/>
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    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EFQ33398.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="410" mass="46973" checksum="82D0D344AE343477" modified="2011-01-11" version="1">MPSRTLPTFTRAEVEAHNNKKSCYVTIGANVYDVTDFAHDHPGGADLVFEYAGKDVEAILRDPTSHPHSEAAYEVLDDSLVGFVINQKTVNGSVSKTNGTVNGKVNGHANGNGNGNDNDTDNGVTKSENEGVKMNERGELWDGERWVHPRTGMASEEDLSKETDYTNDYKKHKFLDLSRPLFPQIWYGGFSKEFYLDQVHRPRHYKGGESAPLFGNFLEPLSKTPWWVVPLAWLPPVAYSLYLAREGMKSTMEESLYFGLGLFLWTLIEYILHRFLFHLDQWLPDNRVGITAHFLLHGIHHYLPMDKYRLVMPPTLFVVLATPFYKLAHCVFSYSWHVATAVFCGGIFGYVCYDLTHYFLHHQNLPLWYKELKKYHLQHHFLDYELGFGVTSRFWDSVFGTELPPIVKAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRK5</accession>
    <name>E3QRK5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Kinetochore protein NDC80</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">GLRG_08772</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the NDC80 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Chromosome</location>
            <location evidence="11">Centromere</location>
            <location evidence="11">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the NDC80/HEC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697371">
        <property type="protein sequence ID" value="EFQ33493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097513.1">
        <property type="nucleotide sequence ID" value="XM_008099322.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRK5"/>
    <dbReference type="STRING" id="645133.E3QRK5"/>
    <dbReference type="GeneID" id="24414137"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08772"/>
    <dbReference type="eggNOG" id="KOG0995">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012583_0_0_1"/>
    <dbReference type="OrthoDB" id="7459479at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031262">
        <property type="term" value="C:Ndc80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051315">
        <property type="term" value="P:attachment of mitotic spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.30:FF:000001">
        <property type="entry name" value="Probable kinetochore protein ndc80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.30">
        <property type="entry name" value="Ncd80 complex, Ncd80 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005550">
        <property type="entry name" value="Kinetochore_Ndc80"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055260">
        <property type="entry name" value="Ndc80_CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057091">
        <property type="entry name" value="NDC80_loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038273">
        <property type="entry name" value="Ndc80_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10643">
        <property type="entry name" value="KINETOCHORE PROTEIN NDC80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10643:SF2">
        <property type="entry name" value="KINETOCHORE PROTEIN NDC80 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03801">
        <property type="entry name" value="Ndc80_HEC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24487">
        <property type="entry name" value="NDC80_loop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 11" id="KW-0132">Cell division</keyword>
    <keyword evidence="10 11" id="KW-0137">Centromere</keyword>
    <keyword evidence="3 11" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 11" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="5 11" id="KW-0498">Mitosis</keyword>
    <keyword evidence="8 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinetochore protein Ndc80 CH" evidence="14">
        <location>
            <begin position="111"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="Kinetochore protein NDC80 loop region" evidence="15">
        <location>
            <begin position="443"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="20"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="321"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="380"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="583"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="21"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="43"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="63"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="119"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
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            <dbReference type="ARBA" id="ARBA00007050"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF03801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF24487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EFQ33493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="726" mass="83291" checksum="9D8A8430B131EE27" modified="2011-01-11" version="1">MSQDTGLWSVRRPRETLVGINYNTGLPQPQSAMKRSASGAGAQYSNNHGRSMSGSRHSLALSRPSQPMFQRSSSGTNLADLGLSSVKRTSMRDKSFAPTPAPGRSSQDADRRSSVYRARTSNAGPMSHQSFFQQAPQPAGVPRDPRPLRDRSYQARIGQELLDYLAQNNFEMQMKHTLSQNIIKSPTQKDFNYMFQWLYRRIDPSHKFQKNIDQEVPPILKQLRYPYERSITKSQIAAVGGQNWSTFLGLLHWMMQLAQMLDGYACNRYDDACLESGIDVTGDHIIFDFLSSAYRDWLAMDEDADDEDANRALAPHIERMAQAFEQSNSKYTSELEMLEGENSRLLREIEDLEKSTPDPAVLDNHFRIMEEDKVKFEEYNALAMQRSDKYETRIQVLQEELEKLNEELREVEDERRGLQKAVDDLGISMQDIDRMTSERERLQKGIESATQRLEEVKRKVADKELEASRKLDELERMVDRYNTLAYQIGLIPATAVNANGKDYELQVTVNDGPDFSASQLKGSSSASSSDRLLADPVTGYQPAHILNLDLRGQVKSSFLTLRKEISERRTVAIDMMMKDHDLLDGIKEAIEDKRNEVEALEHRVRAAEEEYEKTKEVTTTQKMASDAQIEKMEKELAKMRATLTESVQLMEQREMNTSIEYEQLVLRANSLREELHTEIDRMLNDVIKFKIHVQRNLDDYEGFVTDELEKELGSDEMREDTRNLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QS94</accession>
    <name>E3QS94_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class II Aldolase and Adducin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08865</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697373">
        <property type="protein sequence ID" value="EFQ33721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097741.1">
        <property type="nucleotide sequence ID" value="XM_008099550.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QS94"/>
    <dbReference type="STRING" id="645133.E3QS94"/>
    <dbReference type="GeneID" id="24414230"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08865"/>
    <dbReference type="eggNOG" id="KOG3699">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006033_1_2_1"/>
    <dbReference type="OrthoDB" id="3238794at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.225.10:FF:000009">
        <property type="entry name" value="Class II aldolase/adducin N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="entry name" value="Class II aldolase/adducin N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051017">
        <property type="entry name" value="Aldolase-II_Adducin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004855">
        <property type="entry name" value="PRK06208.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10672">
        <property type="entry name" value="ADDUCIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10672:SF25">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 14 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="AraD/HMP-PK domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Class II aldolase/adducin N-terminal" evidence="1">
        <location>
            <begin position="70"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ33721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="308" mass="33758" checksum="CD32BDD946F2BB68" modified="2011-01-11" version="1">MSPSAIINDTESAAAEAPGASIVPKDAPHTKHGHELANKTPLQAMSHGEVVLAGIPKFPDFASKRQWQLEHMAAAFRHWAREDYIEGMSGHISVRDPEYHDAFWTNPLGRHFGLLKASDMILVNFDGAVIGGNRSKPPNTAGFLIHAAVHKARPDVHAVCHNHGIYGKAWSVYGRRLEMLTQDACKFRGDAHSVYNSYGGVVLGPEEGEAIAKALGPRGKGCILRNHGLLTVGQTVDEAAFLYTSMERSCRVQLLAEAASANGLQKVLITDEEAQFNFDVESDPEICYCEFQVYYDLEDELTNGAFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSG1</accession>
    <name>E3QSG1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UDP-glucose 6-dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_08932</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>UDP-alpha-D-glucose + 2 NAD(+) + H2O = UDP-alpha-D-glucuronate + 2 NADH + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:23596"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58052"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="1.1.1.22"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nucleotide-sugar biosynthesis; UDP-alpha-D-glucuronate biosynthesis; UDP-alpha-D-glucuronate from UDP-alpha-D-glucose: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.22" evidence="3"/>
    <dbReference type="EMBL" id="GG697373">
        <property type="protein sequence ID" value="EFQ33788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097808.1">
        <property type="nucleotide sequence ID" value="XM_008099617.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSG1"/>
    <dbReference type="STRING" id="645133.E3QSG1"/>
    <dbReference type="GeneID" id="24414297"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08932"/>
    <dbReference type="eggNOG" id="KOG2666">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023810_7_0_1"/>
    <dbReference type="OrthoDB" id="5059218at2759"/>
    <dbReference type="UniPathway" id="UPA00038">
        <property type="reaction ID" value="UER00491"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003979">
        <property type="term" value="F:UDP-glucose 6-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006024">
        <property type="term" value="P:glycosaminoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006065">
        <property type="term" value="P:UDP-glucuronate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.100:FF:000001">
        <property type="entry name" value="UDP-glucose 6-dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000193">
        <property type="entry name" value="UDP-glucose 6-dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.100">
        <property type="entry name" value="Cytochrome c1, transmembrane anchor, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017476">
        <property type="entry name" value="UDP-Glc/GDP-Man"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014027">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036220">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014026">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001732">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028357">
        <property type="entry name" value="UDPglc_DH_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028356">
        <property type="entry name" value="UDPglc_DH_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03026">
        <property type="entry name" value="NDP-sugDHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11374:SF3">
        <property type="entry name" value="UDP-GLUCOSE 6-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11374">
        <property type="entry name" value="UDP-GLUCOSE DEHYDROGENASE/UDP-MANNAC DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00984">
        <property type="entry name" value="UDPG_MGDP_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03720">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03721">
        <property type="entry name" value="UDPG_MGDP_dh_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500134">
        <property type="entry name" value="UDPglc_DH_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000124">
        <property type="entry name" value="UDPglc_GDPman_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00984">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52413">
        <property type="entry name" value="UDP-glucose/GDP-mannose dehydrogenase C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDP-glucose/GDP-mannose dehydrogenase C-terminal" evidence="11">
        <location>
            <begin position="446"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="539"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="546"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="390"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="379"/>
            <end position="383"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="387"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="393"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="453"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="460"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ33788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="686" mass="73580" checksum="0408DF7F0E56992A" modified="2011-01-11" version="1">MYNLGGTAPPASTDDAEEASFHPPSTVPTTPEGSITFSPVVRAESNLTEDGDSISDDAFGELLSDRGGHAASTASTRSTPVTNICCVGAGYVGGPTAAVIAFQNPHIRVTVVDRDERRIRRWNSKHPTIYEPGLRDIVRVARDGANACSFQNEPAKLGGSDVPSSSSSSASRRSITAAARKPNLFFSTEVSGCIAEADIVLVAVNTPTKTRGHGAGSATDMAAFEAVTAEVARHARPGAIIVEKSTVPCMTAELVRETLAAHRPGVHFEIVSNPEFLAAGTAVNDLLHPDRVLIGSDTTSSGRRAAEALAGVYAAWVPRARILTTNVWSSELAKLVANSMLAQRISSINSISAICERTGADVDEVAASVGRDPRIGDRFLKAGIGFGGSCFKKDILSLVYLAESLDLDEVGEYWRQVVKMNEYQRDRFTRRVVKCLNNTLTGKKVTMLGYAFKKNTSDTRESPALEIIRTLLDEEPREMAVFDPCCNPLVIRDEIRRLCGGKSPLKEDGGPLTVCGNVYDACRGSNAVLITTEFDEFRNTKAPPLSQRTPRPSTASPRADVDPRPFRSVEVRQADVLALQWFLAARQDGPAGPGGPLDDPLGRYVAEPGCADDCPDCRAELDSKVSGFATGLGTEEYKPKERVDWARVAGDMQVPRWVFDGRGVVDAKSMAKLGVRVESIGGRGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSL7</accession>
    <name>E3QSL7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RNA recognition domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_08999</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697374">
        <property type="protein sequence ID" value="EFQ33855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097875.1">
        <property type="nucleotide sequence ID" value="XM_008099684.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSL7"/>
    <dbReference type="STRING" id="645133.E3QSL7"/>
    <dbReference type="GeneID" id="24414364"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08999"/>
    <dbReference type="eggNOG" id="KOG0118">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016304_6_1_1"/>
    <dbReference type="OrthoDB" id="446113at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006376">
        <property type="term" value="P:mRNA splice site recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12611">
        <property type="entry name" value="RRM1_NGR1_NAM8_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12613">
        <property type="entry name" value="RRM2_NGR1_NAM8_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12346">
        <property type="entry name" value="RRM3_NGR1_NAM8_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000065">
        <property type="entry name" value="mRNA binding post-transcriptional regulator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000222">
        <property type="entry name" value="mRNA binding post-transcriptional regulator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000227">
        <property type="entry name" value="mRNA binding post-transcriptional regulator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050825">
        <property type="entry name" value="RBM42_RBP45_47-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47640:SF10">
        <property type="entry name" value="TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47640">
        <property type="entry name" value="TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="59"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="152"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="294"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="363"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="377"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="404"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ33855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="419" mass="44718" checksum="B6E7414AB1DEC62E" modified="2011-01-11" version="1">MDGINPYNPAQGNGAPPPNANGDGFGTPVSGGMPFPGNNGSGEIPGSVQAPNQQDANKNTLWMGELEPWMDENFIKGVFLTATGEPVNVKVIRDKTSGNAGYCFVEFTSSEAASKALTLNGSPVPNSNRAFKLNWASGGGINDRRDDRGPEYSIFVGDLGPEVNEYVLVSLFQARFPSCKSAKIMTDAMSGQSRGYGFVRFTDEQDQQRALVEMQGVYCGNRPMRISTATPKNRNHGGPYQQQHHGNQMMAPGLPPHQQGFYGVPSPAQYGGAYGAPYNPPGQQMNQFTDPNNTTVFVGGLSGYVTEDELRSFFQGFGEITYVKIPPGKGCGFVQFVHRHAAEMAINQMQGYPIGNSRVRLSWGRSQNNSGVGTPYRPAPPPPHYFAPPGPGAYGPAHFGAPGPHGPPGPQGPPGAPPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTL8</accession>
    <name>E3QTL8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_09437</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697378">
        <property type="protein sequence ID" value="EFQ34293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098313.1">
        <property type="nucleotide sequence ID" value="XM_008100122.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTL8"/>
    <dbReference type="STRING" id="645133.E3QTL8"/>
    <dbReference type="GeneID" id="24414802"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09437"/>
    <dbReference type="eggNOG" id="ENOG502QQSB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031217_0_0_1"/>
    <dbReference type="OrthoDB" id="2099887at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027589">
        <property type="entry name" value="Choice_anch_B"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04312">
        <property type="entry name" value="choice_anch_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38787">
        <property type="entry name" value="REGULATORY P DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38787:SF3">
        <property type="entry name" value="REGULATORY P DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ34293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="483" mass="54530" checksum="C5D266619A2120B8" modified="2011-01-11" version="1">MKTVHLALAMGVLSGVSNTRELEPNADLSAWYDSGAAHQENMDYKIAQWEEAEADGKFDSAQWTGRVKDYIACKDGKVELVKGDPLQTFKCKDIDLYDFQPHAAFGNSTGRGSGSWGWTAPDGREFFAIGQLDGTAFAEITKNGKLVYLGTLPYYSEPSRWREIKTYKNYLVVGSEAPGHGIQFFDLRKLLEIDPKNPVIFSNEKDLTAHWIEALPLGRSHNVVVNEEKGYAVAVGAQPRRNLPCDSGLQFLHLADIANPVYLGCAAGDGYVHDAQCIVYRGPDVKYWGRDICYGYNEDTLTIYDVTDKNSTNIISRTSYEGATYTHQGWVFDPNWQDFLVLDDEIDERNRTGPAADGFPVTYFWDIRSLQKPKQSGIFKGTVRSVDHNQFIHRGLAYQSNYGAGLRILDVSSVRWDPTAKHVKEIAYFDIFPEDDNEPGGGANNYTGTWSHYPYFKSGYVVINTIERGVWVVKRSNPWWWPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTV8</accession>
    <name>E3QTV8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_09414</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697378">
        <property type="protein sequence ID" value="EFQ34270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098290.1">
        <property type="nucleotide sequence ID" value="XM_008100099.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTV8"/>
    <dbReference type="GeneID" id="24414779"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09414"/>
    <dbReference type="eggNOG" id="ENOG502SN7N">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013756_0_0_1"/>
    <dbReference type="OrthoDB" id="3026777at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507:SF1">
        <property type="entry name" value="FI18259P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507">
        <property type="entry name" value="ZGC:174356"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="269"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="413"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="437"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="471"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="506"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ34270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="567" mass="61490" checksum="2B14E7A1791F6E35" modified="2011-01-11" version="1">MTRPSDGLKADEYVLSAYPVHEDDLPGADDPDLFCGSFRSPRRFSARGRVGVLFRLVGGGLRAGFRGLDGLLTPFRATSPRAVILVLALLKFTVSYKLAIQMMPIMRLIEDHICHQHYRLGPEARIPEMKCKVDEVQRDLAWLQGWQSLFGAVVNMTVAFPYGVLSDRIGRKAGMLLAYTGTLGAVIWPLLFLARFPEASIYLILVGILFFLVGGGVVVFFNNLYAMAADVSTAKDRASNFVFLSVGAVTGGLLGPVTAGFMMERHGPWAPIRVMFLVVPVILLLMMLLPETLRGRSAGSPPRERLSLGAAVGEALDNGLHEVRESVGILRDRNVMLCLAPSLVQGPLGASHGQTLPQYISKYFGWTLAQTTFLMSPLELGHLAVLLALPWLSRAITDPRGRFRRTGCGKDALLARVSYFMIASGALIGGLSRDVVVFAAGLVVTTLGSASFPVSRALITGFVDPEHTSRLYALASMADTLGSPLGGPVLAWAFSVGMEKKGGWKGLPWFYVFFLATGTWAALMLVKVPKENDPTHLESDDGIEIVGYKPVAGDEPRDATPVRERSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QU92</accession>
    <name>E3QU92_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Clr5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09574</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697380">
        <property type="protein sequence ID" value="EFQ34430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098450.1">
        <property type="nucleotide sequence ID" value="XM_008100259.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QU92"/>
    <dbReference type="STRING" id="645133.E3QU92"/>
    <dbReference type="GeneID" id="24414939"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09574"/>
    <dbReference type="HOGENOM" id="CLU_1825145_0_0_1"/>
    <dbReference type="OrthoDB" id="539213at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025676">
        <property type="entry name" value="Clr5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788:SF3">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14420">
        <property type="entry name" value="Clr5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Clr5" evidence="1">
        <location>
            <begin position="12"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="141" mass="16633" checksum="DEE70D67E40925A5" modified="2011-01-11" version="1">MPPRAKKSDIKDEEWEKFQPEIRKLYLTEDKSLKDLLTILSVSYGFRPSKAQLQWKLTQWRMTKKMITSEWKYVHHRVRLRDTTIEKARVRHCYETALEKTIGVVAPPSPTDLSLIIRTPSPQNVPELDNMYGIPWLQPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>E3QV99</accession>
    <name>E3QV99_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">acetylornithine transaminase</fullName>
            <ecNumber evidence="5">2.6.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_09931</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 4/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.11" evidence="5"/>
    <dbReference type="EMBL" id="GG697384">
        <property type="protein sequence ID" value="EFQ34787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098807.1">
        <property type="nucleotide sequence ID" value="XM_008100616.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QV99"/>
    <dbReference type="STRING" id="645133.E3QV99"/>
    <dbReference type="GeneID" id="24415296"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09931"/>
    <dbReference type="eggNOG" id="KOG1401">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016922_10_1_1"/>
    <dbReference type="OrthoDB" id="5419315at2759"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00109"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003992">
        <property type="term" value="F:N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:L-arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000004">
        <property type="entry name" value="Acetylornithine aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01107">
        <property type="entry name" value="ArgD_aminotrans_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004636">
        <property type="entry name" value="AcOrn/SuccOrn_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049704">
        <property type="entry name" value="Aminotrans_3_PPA_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050103">
        <property type="entry name" value="Class-III_PLP-dep_AT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00707">
        <property type="entry name" value="argD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002325">
        <property type="entry name" value="PRK01278.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11986:SF79">
        <property type="entry name" value="ACETYLORNITHINE AMINOTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11986">
        <property type="entry name" value="AMINOTRANSFERASE CLASS III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 12" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="9 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ34787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="469" mass="50181" checksum="B97884A76C3F0872" modified="2011-01-11" version="1">MAFRAPLRLQLAKCQPLLAVSSRGNARAVSSATAASSLPEDVKSSITSQASLPNPDPTEDSASAALVREHAPYMVATYARPPPVFVKGQGSVLWDIENRQYLDFTAGIAVNSLGHCDPELTKLLTEQGSTLMHASNLYYNPWTGALSKLLVEKTREAGAMHDVNSVFICNSGSEANEAAIKFARKAAKVGQASGDKYEIVSFNNAFHGRTMGSLSATHNPKYQEPFAPMLPGFKLGAFNDVAAINDVVTDKTCGVIVEPIQGEGGVTPATDEFLIALARRCREVGAVLIYDEIQCGLSRTGAFWAHAHLPKEAHPDIITTAKALGNGFPIGATIVNGNVSDKIKVGDHGTTFGGNPLACRLAHNIVSRLADPGLQKAVAAKADIFRTRFDALRERFPDLIKEVRGRGLILGLQLTQDPAPIVKAARERGLLVITAGTNTLRFVPPLTITEQQIQQGLDILEEAISVTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVC7</accession>
    <name>E3QVC7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Glycerol-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="3 7">1.1.5.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_09959</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a quinone + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + a quinol</text>
            <dbReference type="Rhea" id="RHEA:18977"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.1.5.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.5.3" evidence="3 7"/>
    <dbReference type="EMBL" id="GG697384">
        <property type="protein sequence ID" value="EFQ34815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098835.1">
        <property type="nucleotide sequence ID" value="XM_008100644.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVC7"/>
    <dbReference type="STRING" id="645133.E3QVC7"/>
    <dbReference type="GeneID" id="24415324"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09959"/>
    <dbReference type="eggNOG" id="KOG0042">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015740_4_1_1"/>
    <dbReference type="OrthoDB" id="264015at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004368">
        <property type="term" value="F:glycerol-3-phosphate dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.870">
        <property type="entry name" value="Alpha-glycerophosphate oxidase, cap domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031656">
        <property type="entry name" value="DAO_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038299">
        <property type="entry name" value="DAO_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000447">
        <property type="entry name" value="G3P_DH_FAD-dep"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11985">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11985:SF15">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16901">
        <property type="entry name" value="DAO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01001">
        <property type="entry name" value="FADG3PDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00977">
        <property type="entry name" value="FAD_G3PDH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00978">
        <property type="entry name" value="FAD_G3PDH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4 7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="8">
        <location>
            <begin position="82"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-glycerophosphate oxidase C-terminal" evidence="9">
        <location>
            <begin position="489"/>
            <end position="606"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ34815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="677" mass="72667" checksum="F827C464251EB938" modified="2011-01-11" version="1">MPPRFASLRRPVVIAAAAATGGVVAYSTFLSGRGAHSFDKPLVELKRDNQGKIIPPSFPIAKDRASQLADLRAHSSDTHEYDLLVIGGGATGTGIALDAVTRGLKVALVERDDFSAGTSSKSTKLVHGGVRYLEKAVWNLDYSQLELVMEALHERKTFLNVAPHLSSSLPILLPIQKWWQTPYFWAGTKAYDLLAGSQGLESSYYVSTKKALEAFPKLRRDNMVGALVYYDGQHNDSRMNVSLALTAALYGATVVNHVEVTSLEKNSHGKITGAKVRDVMTPGSDSFTVRAKGVINATGPFADAIERMDNPDRKPIVAPASGAHIMLPGDICPNGIGLLDAATSDGRVIFVLPWQGYTLAGTTDNAAPVEREPVAREDDIKFILKEVNKLMTPDAALTRSDVLAAWSGIRPLVKDPNAKNTESLVRSHLVTVSDSGLLTCAGGKWTTYRQMAEDAVDEAIATFKLQPKPVTLPDISGAGLPAFTTTGKCITTNVPLVGAHGFSKHLPSHLASHFSLDADVANHLAHNYGDRAWSVAAASSERIIPNFPFVVGEIRHGVRAEAAMTATDLISRRTRLAFLDAESALRALPHVIDVMAEELGWNEARKKKEWTQTVHFLQSMGLSADKLNVTREEVLRSGDAKSGYAPKAQTAASASGFKTGLGDIQAGGALARNITDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVJ2</accession>
    <name>E3QVJ2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10024</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697385">
        <property type="protein sequence ID" value="EFQ34880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098900.1">
        <property type="nucleotide sequence ID" value="XM_008100709.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVJ2"/>
    <dbReference type="STRING" id="645133.E3QVJ2"/>
    <dbReference type="GeneID" id="24415389"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10024"/>
    <dbReference type="HOGENOM" id="CLU_2558172_0_0_1"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="82" mass="9459" checksum="FD0E89C21558B955" modified="2011-01-11" version="1">MDEFGIILLTIFMVLLACGLLLHRPVRLTYICVRDHCKYHPRASQFQDARRKLNTVSDCTSACPEKQDLESGLNQHDAEPEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVW1</accession>
    <name>E3QVW1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Calcineurin-like phosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_10143</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697386">
        <property type="protein sequence ID" value="EFQ34999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099019.1">
        <property type="nucleotide sequence ID" value="XM_008100828.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVW1"/>
    <dbReference type="STRING" id="645133.E3QVW1"/>
    <dbReference type="GeneID" id="24415508"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10143"/>
    <dbReference type="eggNOG" id="KOG0371">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023125_0_2_1"/>
    <dbReference type="OrthoDB" id="10267127at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000298">
        <property type="term" value="F:endopolyphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006798">
        <property type="term" value="P:polyphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050126">
        <property type="entry name" value="Ap4A_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42850">
        <property type="entry name" value="METALLOPHOSPHOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42850:SF4">
        <property type="entry name" value="ZINC-DEPENDENT ENDOPOLYPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="3">
        <location>
            <begin position="92"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="171"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="330"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="427"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="293"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="208"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="341"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="435"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ34999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="456" mass="49525" checksum="E8D6128ECA2CC145" modified="2011-01-11" version="1">MTFAALRRSAVCIGALFILTTIFLAATRIASSLDFSASRSSPARDVPAPPRSPADAPMSYGLNARPGFTDLSVHIASLPERHRPSRAHPGRRLVIVGDVHGMHASLERLLDELRFAVAAGDHLVLAGDMINKGPDSPGVLDLAIRLGASAVRGNHEDRVLLAHRSMQNTHVANEDAHGNPVMTKGEEIEGQPKAEEPKDEPKSATAAEVDDNDEEEDDLEPAVFSHGDSQERATARRLSRKHLAWLASLPVILEAGTIEGLGDLVIVHAGLVPGVPLPRQDPWAVMNMRGLVYPREELRRQEAKRALEDARKAYNAASLIAVGPITETMVEREHERRRRPGDREPAIPTDRHDGASSWPKAWDAHQRALPEATPRTVVAYGHDSKRGLHVGQYTFGLDSGCVNGGELSALVIEATAEGVTHVVRSVSCAGDEGKKKKRKGRKHKKGKKSKKQEDQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QW79</accession>
    <name>E3QW79_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_10257</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697388">
        <property type="protein sequence ID" value="EFQ35113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099133.1">
        <property type="nucleotide sequence ID" value="XM_008100942.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QW79"/>
    <dbReference type="STRING" id="645133.E3QW79"/>
    <dbReference type="GeneID" id="24415622"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10257"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_8_4_1"/>
    <dbReference type="OrthoDB" id="440553at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000172">
        <property type="entry name" value="MFS multidrug resistance transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF151">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="55"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="292"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="329"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="391"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="415"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="456"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="480"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="57"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ35113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="528" mass="56317" checksum="8CF611DE045DDF8B" modified="2011-01-11" version="1">MPEKAKANFQDAEILVSESPVPVPGTDGVPGSSDVSLGEPDLMAVYSRFTPTQRIVIIAVASTIGLLSPLSSNLYTPAIPAVARDLNVSTDAINLTITSYLVLQGISPTLWSAIGDSTGRRLLFLIALTIYLASCLGLALSRNYPAVVALRAVQAVGSASTTAIGASLIGDLIHVSRRGKYMGNYSALGGAGTAFGPVIGGVFAQYTGWRGMFVFLASLAAFLLLFTALLLPETKRGIVDDGSIRPPRYLRAPLEWLDAPKSGNGVADAKAGSRFPIDTGAPVRLLVEPECLCIVIFTVICYTVWQVTMVATATLYAERYGLDEMSIGLTYISNGVGSLCCSVLTGKLLDREYKHQLRRERAAQQAAADNADGLPPVKEVQHIELARIKPVIIPTVAYLVSVVALGWIIEFHVHIAASITMSFFVGGLDTIILAAFSTLIVDLFRSQSFSATASMNLSRCLLASGGTAAIGPLIRAVGVGWAFTLCAMVALASCSLALLELWRGRHWRAKRMREAVQREKAASRTEPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWH7</accession>
    <name>E3QWH7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_10359</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697389">
        <property type="protein sequence ID" value="EFQ35215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099235.1">
        <property type="nucleotide sequence ID" value="XM_008101044.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWH7"/>
    <dbReference type="STRING" id="645133.E3QWH7"/>
    <dbReference type="GeneID" id="24415724"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10359"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_0_1"/>
    <dbReference type="OrthoDB" id="4131217at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (AFU_ORTHOLOGUE AFUA_6G11210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180:SF66">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ35215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="303" mass="31830" checksum="FCCD1C5D6750269E" modified="2011-01-11" version="1">MSDKAQQRLQALGKHLDAPPPLKIAGPSAAPRVPGKVIIITGANSLMGIGRASAHQFAENGARAIYICDYANDNLEPHKSELNKLYPKVDVHTRQFDAADETAVKEVVSHAITTYGRLDVFFANAGITGPHNVFTDIGEEDFMQNMRTNVLSVFLAAKHSAPAMAKTSTEKKTPGGSIILTASVAGLRSNAGTTPYSAAKAAVISIAQTCAYQAAGSNVRVNAICPGLIETGMTSLMYDTARARGTQSKIGQVNPLKRGGHADEIARVALFLGSDESSYVNGQAWAVDGGLSAGHPYVLGKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWI3</accession>
    <name>E3QWI3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10365</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697389">
        <property type="protein sequence ID" value="EFQ35221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099241.1">
        <property type="nucleotide sequence ID" value="XM_008101050.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWI3"/>
    <dbReference type="STRING" id="645133.E3QWI3"/>
    <dbReference type="GeneID" id="24415730"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10365"/>
    <dbReference type="eggNOG" id="KOG0057">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_88_0_1"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042626">
        <property type="term" value="F:ATPase-coupled transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221:SF654">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="1">
        <location>
            <begin position="35"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="155" mass="17250" checksum="1CC58C2FC29B43F8" modified="2011-01-11" version="1">MPVQVEHGPDFDFQGGAIDFTNVEFSYEGKKDSTLNGLYLQIAAGTKVSIIGKSGSSKSTMLKLLLGLLEPSSRYRQVNNQKVEDISISSLRSHIRIVAQNARLFNQSVMDNIRWFANQDVTDVEVKNACRRACIHQTIKSLPDGYRTKIGDDGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWR1</accession>
    <name>E3QWR1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Acyl-CoA dehydrogenase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_10443</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697391">
        <property type="protein sequence ID" value="EFQ35299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099319.1">
        <property type="nucleotide sequence ID" value="XM_008101128.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWR1"/>
    <dbReference type="STRING" id="645133.E3QWR1"/>
    <dbReference type="GeneID" id="24415808"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10443"/>
    <dbReference type="eggNOG" id="KOG0140">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_4_1_1"/>
    <dbReference type="OrthoDB" id="10254877at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050741">
        <property type="entry name" value="Acyl-CoA_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083:SF28">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G10880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083">
        <property type="entry name" value="MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0274">FAD</keyword>
    <keyword evidence="3 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="9">
        <location>
            <begin position="38"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="8">
        <location>
            <begin position="164"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="7">
        <location>
            <begin position="271"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ35299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="435" mass="48539" checksum="9192766E0B056AC0" modified="2011-01-11" version="1">MSDTYAKTLGSFAPYYPVPSSFLQVAWFNALESPYYNDSHQRFQAYVRHYVDTYLLPHAQEWEAAGEAPLAARLKFAKSGLAFLDVPREYRPEEVMTVAGIPFDDIDVFHELILMDEMARIPSGVPLALAGASNVGAPPIFVAGTTEQKRRWLPGLFTWETSFCLAITEPTAGSDVSAIRTTAKKTPDGAHYVVNGRKKWITGAPWATHMTTAVRMGEKGQGGISLLVVPLTLSGITIRKIHNSGHNAGGSSWVILEDVKVPVDHLLGRENEGFPIITRNFNKERFILTVDCNRQARVCLSEALQHAHDRETFGKTLASHQIIRHKLTTLAREIEGHWAWLEQIAYHVKVHGWQTKDIASRIALAKIQGGRIVEQAVRESQQIHGGMGYEKGMTMTEQISRDLRLKVIGGGSEEILGDLAWREEHKRANDRLSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QX06</accession>
    <name>E3QX06_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_10538</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. TCR/Tet family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697392">
        <property type="protein sequence ID" value="EFQ35394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099414.1">
        <property type="nucleotide sequence ID" value="XM_008101223.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QX06"/>
    <dbReference type="GeneID" id="24415903"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10538"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_22_1_1"/>
    <dbReference type="OrthoDB" id="10021397at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF193">
        <property type="entry name" value="MULTIDRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G00940)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="255"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="284"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="328"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="368"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="394"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="420"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="456"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="532"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="64"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ35394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="556" mass="59330" checksum="50C19ED2054848ED" modified="2011-01-11" version="1">MANQPVVSPASQDSRDSEDVSQNDELLAPYSDMEDRPPNHSQEVPQCDDGTKAYAITDAKFILVVAALTLTSFLVMLDMSILPTAIPEITTEFHSLRDIGWFGSAYLLASSTMQPLTGKLYLGFGLKHPFLAFLGVFELGSLLCGVAPNSRLFILARAIAGLGASGLLNGALNIIAAITPMHKRPALIGFMMLIGQLGMIGGPLIGGFLTQYAGWRWCFYINLPIGAISAVILSSITIPDGFVRTAAKNTTALSVFLSLDPIGFVLFSALTVTLFMALQWGGSVYAWSNPVITGMLCASGGLFAVFSAWEKFVGENAMFPYSVLRKRVVWASCLTMFLMQGCALIYLYYLPIYFQAVRGSSPLSSGVYNSPGIGSQMLLAAISGVLVGKMGYYLPWVIASGILGLVGSGLISALRPDTSPAVWIGYQIIAGVGRGCGSIMPMVATQSALSPEQTPLGMSLVAFCQSFGGSVFLTFAQVIFSYSLVDGLKTFAPTVDIQTVIDAGAAGLRDVVRPEELAGVIEAYNLSFTREFHLAAAAYTAMIFSGWGMGWYSVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QX26</accession>
    <name>E3QX26_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Defective in cullin neddylation protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_10558</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.</text>
    </comment>
    <dbReference type="EMBL" id="GG697392">
        <property type="protein sequence ID" value="EFQ35414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099434.1">
        <property type="nucleotide sequence ID" value="XM_008101243.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QX26"/>
    <dbReference type="STRING" id="645133.E3QX26"/>
    <dbReference type="GeneID" id="24415923"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10558"/>
    <dbReference type="eggNOG" id="KOG3077">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047042_1_2_1"/>
    <dbReference type="OrthoDB" id="27198at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000151">
        <property type="term" value="C:ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097602">
        <property type="term" value="F:cullin family protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031624">
        <property type="term" value="F:ubiquitin conjugating enzyme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032182">
        <property type="term" value="F:ubiquitin-like protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045116">
        <property type="term" value="P:protein neddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.200">
        <property type="entry name" value="Cullin, PONY binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014764">
        <property type="entry name" value="DCN-prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042460">
        <property type="entry name" value="DCN1-like_PONY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005176">
        <property type="entry name" value="PONY_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12281:SF31">
        <property type="entry name" value="DCN1-LIKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12281">
        <property type="entry name" value="RP42 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03556">
        <property type="entry name" value="Cullin_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51229">
        <property type="entry name" value="DCUN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DCUN1" evidence="2">
        <location>
            <begin position="1"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU410713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ35414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="208" mass="23850" checksum="1CA53F65FD3F69F2" modified="2011-01-11" version="1">MFDKLRDDSKDEKDSLGLDTTMAYLQDLGVNLENAELLVVMELLQAPSVGEITRKGYVDGWKATGAATRQGHVAHIKSLVSSLSTDPAYFRKVYRHTFVASKEPNQKALNLEIAIVYWNVLFSPPGWLWKTKNHDWLQLWLKFLEEKWTRSVNRDMWNQILEFATKTMADETLSFWSEDGAWPSVIDDFVAWCKEKGVGKAETMDLDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXB0</accession>
    <name>E3QXB0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10642</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697394">
        <property type="protein sequence ID" value="EFQ35498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099518.1">
        <property type="nucleotide sequence ID" value="XM_008101327.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXB0"/>
    <dbReference type="GeneID" id="24416007"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10642"/>
    <dbReference type="eggNOG" id="ENOG502SN86">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002639_2_12_1"/>
    <dbReference type="OrthoDB" id="47007at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF8">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="187"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="638" mass="72255" checksum="15785EE19F12ABC6" modified="2011-01-11" version="1">MPLCKACSRLDLGDLLDEDDELQDLVLHDSLAVLKESTTSCDLCRLFFSSITNKLRDEGVGVDESTWSDPNSRVILRGIRYQDEDYLPSGLFWVKVRCDTLSPRAYSYFGLYPEEETQGLEGAIIGRLIKPPEEQISLVNDWVTSCDRVHKGCHSDPGALPTRVVDVGLDGHREPRLVVTGGAAGRYVTLSHCWGLHPVIRTTSETIEDHLKALPLGKLPQTFRDAVLITWSLGIQYIWIDSLCIVQDSTEDWELESVKMGTIYASSYLTIAASASKDSTGGCFRSRSTSTDVKVRFTVRDSGDPRSTSVFVRPRPRDFSHLPMSALHSRAWVTQERLLSARMIHYDTDQLLWECRESRLTEDGVPVGAFGGAGNAEWDERLHFSYPFSQSRSRPNFVWDWYDMVSAYTSRGITKSYDRLPALSGLANAMEECTGQKYVAGLWGFHLAYGLLWRRSEQWLRKPADGYRAPSWSWASLEGRVYMPEIATMAPYGNEMEIMIDIVDVHTTPLGLDPRGMLRSGCLKLKGKLKVADSRVDPATPGHKRFPTYPKELAIDFLNCNDEMVGLAYFDEKYSGKERSLHYLQVARKPMEPSRWHGLLLEPTDEKNQFRRVGFCRTEEIPSRDWFADADEEIITIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXB2</accession>
    <name>E3QXB2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Amino acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_10644</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697394">
        <property type="protein sequence ID" value="EFQ35500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099520.1">
        <property type="nucleotide sequence ID" value="XM_008101329.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXB2"/>
    <dbReference type="STRING" id="645133.E3QXB2"/>
    <dbReference type="GeneID" id="24416009"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10644"/>
    <dbReference type="eggNOG" id="KOG1286">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007946_12_1_1"/>
    <dbReference type="OrthoDB" id="3900342at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000001">
        <property type="entry name" value="Amino acid permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF39">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="128"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="193"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="277"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="378"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="409"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="455"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="488"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="8">
        <location>
            <begin position="49"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ35500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="561" mass="61423" checksum="696B9CF2A31FF36B" modified="2011-01-11" version="1">MASVTEEKTVGLSRADSTNSNKLGQVMSGDGAAVAQKYGETQRGLSPRHVQLMAIGGSIGTGLWVGIGGVLSKAGPLSLLLGYTFWGLLFIWPLNLSVAEMCAYLPIRGTIFELASRFVDPALGFAMGWTYFFAGLMLVCTEYSAVATVISYWNADINPSAWIAVAMISCVAVNLIAVKYYGESEFIMASTKVVLLVGLCLITLITMSGGNPTNDAYGFRNWGDGNHIHAYFTDGSTGRFLGFWKVVIYAAFTIAGPDMIALAAGEIQNPRRTIPRVAKLIFYRLVGFYIVGVLCVGIICSSRDPGLLGAIENGEPGAGASPWVIGIKNLHIKALPDIINAFILLSGWSCGNAYLYSTSRTLYGLARDGQAPKFLLKCTSAGVPIYCVLIVTLISCVTFLVSSNSAVEVFFWFVDLTTTALIMTYTFMLITYMGFYRARVAQNFPPETLPYLAPLTPYFPALALLLGILALIFVGFDNFYPFSVRGFITSYFGLIFGIFTFVVWKVLKKTKFVQPKEADLISGKAEVDAECRHWEEGGIEDVERQRLSQMSVLRRTWEKMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXI3</accession>
    <name>E3QXI3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Metallo-beta-lactamase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_10715</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-beta-lactamase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697396">
        <property type="protein sequence ID" value="EFQ35571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099591.1">
        <property type="nucleotide sequence ID" value="XM_008101400.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXI3"/>
    <dbReference type="STRING" id="645133.E3QXI3"/>
    <dbReference type="GeneID" id="24416080"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10715"/>
    <dbReference type="eggNOG" id="ENOG502S1A6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030571_1_0_1"/>
    <dbReference type="OrthoDB" id="10250730at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07730">
        <property type="entry name" value="metallo-hydrolase-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051013">
        <property type="entry name" value="MBL_superfamily_lactonases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42978:SF5">
        <property type="entry name" value="METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42978">
        <property type="entry name" value="QUORUM-QUENCHING LACTONASE YTNP-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="5">
        <location>
            <begin position="49"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ35571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="383" mass="40759" checksum="CBE87665EAA8F91E" modified="2011-01-11" version="1">MSATDSLNIPASTSTVHVSVIDTTLDGDLPTAPFMGPAIKGFERWHGVGYAFLVTHADAEGNERRVVFDLGLPKDWENDFSPPIIEAAKAMDMTMTAQKYVSEILAENGVDLGSIEALIWSHAHPDHIGRPSLFPPSASLIVGPGVKQAYFPGWPAVPDAPILAREFQGREVRELDFGAADLEIGGLGALDYFGDGSFYLLSAPGHAVGHVNALARTTADSYIYMAGDSFHHSSCCGRTPARGCPRTCACREGGGCAARGGRSTPSTPVAGNAAELKHYSRVLGPAGGDADGIAFNTIPETPDGATLLALDVREARETVEAVKRFDASPDVLVVAAHDGSLYGVMEYFPKGANEWKSKGWRESGRWLFLRDFEKPLEVAGVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXL4</accession>
    <name>E3QXL4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_10746</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697396">
        <property type="protein sequence ID" value="EFQ35602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099622.1">
        <property type="nucleotide sequence ID" value="XM_008101431.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXL4"/>
    <dbReference type="STRING" id="645133.E3QXL4"/>
    <dbReference type="GeneID" id="24416111"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10746"/>
    <dbReference type="eggNOG" id="ENOG502SMK9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_25_4_1"/>
    <dbReference type="OrthoDB" id="3934549at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF129">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="26"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="93"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ35602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="307" mass="34747" checksum="A497E877F2AB9BFA" modified="2011-01-11" version="1">MRFPPATVMLTWPSPNHVNPTERGPALIIVELTSLSVALLCLCLRLYVRFFIIRKSWWDDWLMIAATLLEDSSSWPIIPTVNVDGHCCHLRPVIGFLVVLWTQCIPAWHYWDLFVENRKCLDEWPPLAAQSVSMVVIDVIVYMIPIPTLVRLKLPAAQRLVLIFLFSLGTVVVVAGAMRTYWVHHVGMQTYDVTWEGFELWIWTALEANLDVVCGCVPVLRPLLLLTSGCKSPNLVEISFPPTIGSGEKEKGKHGNLEYDAGEHMLNTPLSTPSNSLSTPLQLSSPGWSPILDEWARQQHQKQFRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QY05</accession>
    <name>E3QY05_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AMP-binding enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_10898</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697399">
        <property type="protein sequence ID" value="EFQ35743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099763.1">
        <property type="nucleotide sequence ID" value="XM_008101572.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QY05"/>
    <dbReference type="STRING" id="645133.E3QY05"/>
    <dbReference type="GeneID" id="24416263"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10898"/>
    <dbReference type="eggNOG" id="KOG1176">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_11_1"/>
    <dbReference type="OrthoDB" id="2962993at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031956">
        <property type="term" value="F:medium-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05941">
        <property type="entry name" value="MCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201">
        <property type="entry name" value="ACYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201:SF28">
        <property type="entry name" value="ENZYME, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G01530)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="1">
        <location>
            <begin position="21"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="1">
        <location>
            <begin position="274"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="2">
        <location>
            <begin position="485"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ35743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="591" mass="63744" checksum="4C58D4F04376D4DB" modified="2011-01-11" version="1">MMASLCRTPLFKVLSEADASSVAIVNQSTGTVFSYRSLIRDVARARHALLESVGDKSLTGQRIGFIVENGYGFVVTFLSILASSAVAVPLAPSHPLSELRYILNDSAATVVISSAAHAKQAQQVVAEGLDNVPVLHQISEFDAQNEDDIDVEWTDAPGGATSGMMLYTSGTTARPKGVLLREACLLAQAQSLHKAWDYRPSDRLLHILPLHHIHGTMNALLAPLLAGSSVEFMIGFNAERVWSRLAAPFLPVNGNGIINGTSNGTGDKAVFQPITFLTAVPTVWARMLSAYPSLSTEIQRAGREAISVRHLRLNISGSAALPAPTRDAWTKLSGGNTLLERYGMTEIGMAISCGLDYSDRVESSVGWPLPSVEVRLAEKNDDTGEETIIGLGEEKDPATGKERQGEIQIRGSTIFSEYWRNPAATEKEFTGDGWFRTGDIAVRRAVPGAGEGKSGSWARGPAYFIQGRRSADIIKSGGEKISALEIERELLGLPNVAECAVVGLPSEAWGQKVAAVVVLSDAGKNSAEPWGLKEMRRDLKVHIPPFKVPQDLEIVDSIKRNAMGKVNKKDLVAAVFGDTERIRRRSISGRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QY52</accession>
    <name>E3QY52_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_10985</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697400">
        <property type="protein sequence ID" value="EFQ35790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099810.1">
        <property type="nucleotide sequence ID" value="XM_008101619.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QY52"/>
    <dbReference type="STRING" id="645133.E3QY52"/>
    <dbReference type="GeneID" id="24416350"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10985"/>
    <dbReference type="eggNOG" id="ENOG502S40C">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077179_0_0_1"/>
    <dbReference type="OrthoDB" id="2131339at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021487">
        <property type="entry name" value="DUF3140"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021331">
        <property type="entry name" value="Hva1_TUDOR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40630:SF1">
        <property type="entry name" value="DNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40630">
        <property type="entry name" value="POSSIBLE DNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11338">
        <property type="entry name" value="DUF3140"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11160">
        <property type="entry name" value="Hva1_TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hypervirulence associated protein TUDOR" evidence="2">
        <location>
            <begin position="253"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ35790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="317" mass="34995" checksum="93A3DDED963390A7" modified="2011-01-11" version="1">MVKGRDEVVSEFNEYVNMTADELESWLKSDDSNSAGWPKDDAEGDGETVGHDSGRKIVEILQANPDKKEDEYTDDQVEHMRKVVAYCKRHLAQESKSNSEKSTEDVKKTKSYASLKNWGHDILKAQGKEGGAEKSNGKSSNEKEEEEEEAVEEENGEENGEEEENAEEEEEVKDAEEVDDGEKEETDDKVEEKAGEKRKHADNDENGTSKKLQTRQGEGQAAEKSEENGDEEEEEAADEGGDGQETTKGPEKGDTVSWNWGNGQPEGKVLDVKGEKTTIETKSGNEVSRDGKPDDPAVVLDAGKSKAIKLAHELNES</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QY70</accession>
    <name>E3QY70_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Putative phospholipase</fullName>
            <ecNumber evidence="4">3.1.1.47</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_11003</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + acetate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17777"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30909"/>
            <dbReference type="ChEBI" id="CHEBI:36707"/>
            <dbReference type="EC" id="3.1.1.47"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the serine esterase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.47" evidence="4"/>
    <dbReference type="EMBL" id="GG697400">
        <property type="protein sequence ID" value="EFQ35808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099828.1">
        <property type="nucleotide sequence ID" value="XM_008101637.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QY70"/>
    <dbReference type="STRING" id="645133.E3QY70"/>
    <dbReference type="GeneID" id="24416368"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11003"/>
    <dbReference type="eggNOG" id="KOG3847">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024458_0_0_1"/>
    <dbReference type="OrthoDB" id="2363873at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003847">
        <property type="term" value="F:1-alkyl-2-acetylglycerophosphocholine esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016715">
        <property type="entry name" value="PAF_acetylhydro_eukaryote"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10272:SF7">
        <property type="entry name" value="PHOSPHOLIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10272">
        <property type="entry name" value="PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03403">
        <property type="entry name" value="PAF-AH_p_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018169">
        <property type="entry name" value="PAF_acetylhydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 4" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="3 4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="524"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="277"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="328"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR018169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR018169-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ35808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="571" mass="62854" checksum="F22D3847768C13E8" modified="2011-01-11" version="1">MPAAKAPPTAAEKVASFFSRLSPVPAFPDYTGPYKVGTVDIEVPVAELESPSPTPYSASEILTVQCRVFYPATPESNGKRINWLPSPQRQHVSAYTQFIGIRPMLAEIVSFLPRHLHYTTIPVHKNAEILDPDTPNRRWPTMIFSHGLGGNRNTYSHLAGSLASHGVVVICPEHRDGSAVASFVRIPGKQDQYFMRDTRRTIPYIRLDHEPRPEIYEAREDQLRIRLWELGLIHVVALNMDLGLAMSNLNKSTPSLTQFKNKLHVHEPGSIIFGGHSFGSASIVQFLKSTYYAESSALAHVAKPLFTPRRDSALCQQITEKNVTMLLDMWCFPLLAPGSSELFDLPLPAYANSPSAPGGSALLAVESDAFFKWTDHLHVTARVLSPQPSVNVITPQLFSRSGVRLAEPNFFYVPTSAHLSQSDFGILFPWLTKKIFNSEEPERALRLNLRAQLQILRTNGVPVARTWIGDLVDGTGSGKMGIAGDEDADNGPDDGLMDDKAIFDRSEGKVRFWKWIDVIGMGEPRETPSAGGSANVNAQVAGVERTDQDMEEELEPLQAVASAAQAGAIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYC6</accession>
    <name>E3QYC6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Homoserine O-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_11055</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. MetX family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697402">
        <property type="protein sequence ID" value="EFQ35864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099884.1">
        <property type="nucleotide sequence ID" value="XM_008101693.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYC6"/>
    <dbReference type="STRING" id="645133.E3QYC6"/>
    <dbReference type="GeneID" id="24416420"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11055"/>
    <dbReference type="eggNOG" id="ENOG502QRIX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028760_5_0_1"/>
    <dbReference type="OrthoDB" id="191364at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004414">
        <property type="term" value="F:homoserine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009092">
        <property type="term" value="P:homoserine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00296">
        <property type="entry name" value="MetX_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008220">
        <property type="entry name" value="HAT_MetX-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01392">
        <property type="entry name" value="homoserO_Ac_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001209">
        <property type="entry name" value="PRK00175.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268">
        <property type="entry name" value="HOMOSERINE O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268:SF11">
        <property type="entry name" value="HOMOSERINE O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000443">
        <property type="entry name" value="Homoser_Ac_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="5">
        <location>
            <begin position="59"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="245"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="254"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="279"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="356"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000443-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ35864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="440" mass="47919" checksum="5AD44C150A668AA4" modified="2011-01-11" version="1">METVLLLDSDPNPFNFYARLIHSQRFASIPSLPLDSGEVLHDCPVAYKTWGKLNERGDNVLVICHALTGSSDVGDWWNPLIGPGKALDPPYFFIFCGNVFGSPYGSASPLTVNPDTGRRYASEFPQTTVRDDVRAHKMVLDALGVKSVAAVVGGSMGGMTTLEWPLCTPPGFVRNIVPIATAADHSAWGISWAETQRQCIFFDPKFDDGYYDPTPEGQPSAGLSAARMIAMLTYRSCTSFDSRFGRKPPLAPSKHPDHPLDLPRTDIAPPGTREGCPETPTSQRTRGPSFSVQRYLHYQGEKFLKRFDANCYLHITAKMDSHDVAYGRTQRCGDDGLAEVLPSMPAGALVIGVETDALFLPEQQQRLAAHLPGASLSVLKSSDGHDGFLLEFEQLNTLIQPHLRSRLSDIYAAACGSADSASLDTKAGVNESLTGELESW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYD9</accession>
    <name>E3QYD9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11068</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697402">
        <property type="protein sequence ID" value="EFQ35877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099897.1">
        <property type="nucleotide sequence ID" value="XM_008101706.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYD9"/>
    <dbReference type="GeneID" id="24416433"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11068"/>
    <dbReference type="HOGENOM" id="CLU_1354514_0_0_1"/>
    <dbReference type="OrthoDB" id="10489694at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="202" mass="22965" checksum="B4219DABEB666624" modified="2011-01-11" version="1">MAPPRTKTDSRTSLSDVETDVTKTTAWAAPKDTSMLSAVDQMLLNNMEILAKQNNVIMSLLLQSQREGGRIPNMSKTPRRNDAKPASDSEEEAEHIDCLKEKYTDILFRAYRDFTKSTKKTPFIKRGSTKNLEQDVADFKEHVLNHDWKGILPDWSVSFLLIWGCVRSLMASKSHEKTTEDEIIDIGSDEDARSMTKKRKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYV2</accession>
    <name>E3QYV2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_11184</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697407">
        <property type="protein sequence ID" value="EFQ36040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100060.1">
        <property type="nucleotide sequence ID" value="XM_008101869.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYV2"/>
    <dbReference type="STRING" id="645133.E3QYV2"/>
    <dbReference type="GeneID" id="24416549"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11184"/>
    <dbReference type="eggNOG" id="KOG1201">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_5_0_1"/>
    <dbReference type="OrthoDB" id="10253736at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24322">
        <property type="entry name" value="PKSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24322:SF736">
        <property type="entry name" value="RETINOL DEHYDROGENASE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="Ketoreductase" evidence="5">
        <location>
            <begin position="96"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ36040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="353" mass="37860" checksum="360CB20ABD091A4A" modified="2011-01-11" version="1">MKRFTVDVLLRLLSVTILHPVVSFLVPCGLVLSGIEPSPIELGTDLRSTRWVGPSSGNMRWALWCVAFAWVLSLNRFLNHRALNPASKAKPDFSREVVVVTGGSTGIGAKLVRKLEVAGATVVVLDKAPLSYNTGPRTSHIQCDISSSDDVHAAAKAIRDRHGHASILVANAGLVRGNGLLAATDEDLRSTFNVNVLGLLWTVRAFIPAMIAKNRGHVLVTASSTAFLTIAGMSDYSASKAAVGSLVEGLHTELKHRHGNPAVAVSAIYPATIGTAMFRNLDAPDTFLTPILDPDEVAQKMFDILATGQSENAYMPALALAKVWFRVLPTWMRVAVQDMLSHMADGIGGRNQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZ51</accession>
    <name>E3QZ51_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_11283</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697410">
        <property type="protein sequence ID" value="EFQ36139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100159.1">
        <property type="nucleotide sequence ID" value="XM_008101968.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZ51"/>
    <dbReference type="GeneID" id="24416648"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11283"/>
    <dbReference type="HOGENOM" id="CLU_2922502_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ36139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="61" mass="6766" checksum="B7EC607951897919" modified="2011-01-11" version="1">MAGGTVGGWSWSSRMYKPTYPGTPSTRYTSSYLDKIRRCLTEDTSSICSRHHCPRGPVGPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZ64</accession>
    <name>E3QZ64_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_11296</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697411">
        <property type="protein sequence ID" value="EFQ36152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100172.1">
        <property type="nucleotide sequence ID" value="XM_008101981.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZ64"/>
    <dbReference type="STRING" id="645133.E3QZ64"/>
    <dbReference type="GeneID" id="24416661"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11296"/>
    <dbReference type="eggNOG" id="KOG1721">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005733_1_0_1"/>
    <dbReference type="OrthoDB" id="1405595at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF18">
        <property type="entry name" value="NICOTINATE CATABOLISM CLUSTER-SPECIFIC TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="55"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="78"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="280"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="280"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="305"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="345"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="356"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ36152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1006" mass="113090" checksum="78BACB247F96E047" modified="2011-01-11" version="1">MAMAAIHDNHRRSESSDGLVGVEKIFACTHPGCQRRFTRAEHMQRHALNHMPGGLSCDLCSAHFKRPDLLKRHMDRHRQKDLEAGGPGYGTLDTRKRSWKAPDGSVVEKRPCPNPSGRGQGGSGRGRTQPQQVPSPEPELNEEHNLSSLDPGGSQCYSGGSISPEAPRNPALDLRPGNLNINHSYAFGRGGVFIPSDTINHFSGFPPPIQSSDLITTAAGQFEIDASQAGSWSETSLFSGQQLDYDQVFQPDTASSFNMPYTTALDYNWLFDMQDFSASAANPTPTNTTQQVDARGSTHPPPTRTQPNLVVTPESMKSAQLWTEPMEASSQQPKRADRPPGRSDAFQTETQASRRQIPDSSRERSSDASVSRTHTCRDMPPATRQKYTDSRQAPVEPERPLSSLRKPLIIPSISADVRQRLLEVVDAARPSLPDQRFTIWEHPLLSIDSLKAYLGLFFTRFNTAYPLIHLETFDCRKIEPLLLLSILLLGATYSNKDCHQLAVCIHDVIRPSIFAHAGFSPRPELWTLQAILLVECFGKSRAGQKQHDMSHLFHGLLINLIRRSDCQSVRPPGPPPILGEDNAEALDRAWRKWAEGEQKKRLALLCFMWDTQHAVLFCQSLCMSAFELRLELPCSQSIWEARDAASWAAAWRSSLSDQRLFYLPTLKSYLTPSAPRPSGLTGFSRVLVLHGLMSISWDMGRRDQTALGVVSHDSFGTGWRRLLSTAYDAWKSDFDAYCTAFSAPPENASQARSQGIHGNDRDDEVRRVEFESFASAYKALYHSAQALLNMDFLDVQIYAGARHILGRPVQQRDYHRSARVVKRWATCSDTQPRYYLSSARLDRRDVDDNGNQSKQSASGAAWHAARMLQETRGIHKNTEAMNLFHVPWCLYLATLTCWAYHHARPSRSHRSSSRRSFDEFDDDAELEEDEMIWDPQGEMEALITSMSERADRSEVTLRRERKRTNGLVWIMADILTTVRWGIVHAGVVVLRGLVPQRLINQYEKVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZS2</accession>
    <name>E3QZS2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11505</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697420">
        <property type="protein sequence ID" value="EFQ36360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100380.1">
        <property type="nucleotide sequence ID" value="XM_008102189.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZS2"/>
    <dbReference type="STRING" id="645133.E3QZS2"/>
    <dbReference type="GeneID" id="24416869"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11505"/>
    <dbReference type="eggNOG" id="ENOG502S02V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066046_1_0_1"/>
    <dbReference type="OrthoDB" id="10006218at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026913">
        <property type="entry name" value="METTL24"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32026">
        <property type="entry name" value="METHYLTRANSFERASE-LIKE PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32026:SF10">
        <property type="entry name" value="METHYLTRANSFERASE-LIKE PROTEIN 24-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13383">
        <property type="entry name" value="Methyltransf_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="180" mass="20570" checksum="219CB74BBDD5F078" modified="2011-01-11" version="1">MPASYDWGVEHIGRLGDGGKWVCGMSQCEDYAKDRECVMYSFGVRDESSFEQEMPSRTDCVVWVYDFSVKDFGSQVDSKHHDQAHFKQIGIAGTTDTTLFYSIADLMEMNGHDYIDILKMDIDEAKYDALDSLHRDFPASTGEELPIGQLMVEIHIYDNKNSMIVLDWWERLEARGLCSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZX9</accession>
    <name>E3QZX9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetylgalactosaminide beta-1,3-galactosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.122</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_11545</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.122" evidence="4"/>
    <dbReference type="EMBL" id="GG697423">
        <property type="protein sequence ID" value="EFQ36417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100437.1">
        <property type="nucleotide sequence ID" value="XM_008102246.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZX9"/>
    <dbReference type="STRING" id="645133.E3QZX9"/>
    <dbReference type="GeneID" id="24416909"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11545"/>
    <dbReference type="eggNOG" id="KOG2246">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033556_0_0_1"/>
    <dbReference type="OrthoDB" id="414175at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016263">
        <property type="term" value="F:glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026050">
        <property type="entry name" value="C1GALT1/C1GALT1_chp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003378">
        <property type="entry name" value="Fringe-like_glycosylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033:SF40">
        <property type="entry name" value="APPLE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033">
        <property type="entry name" value="BETA1,3-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02434">
        <property type="entry name" value="Fringe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="Fringe-like glycosyltransferase" evidence="13">
        <location>
            <begin position="195"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ36417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="446" mass="50305" checksum="A93FFDBEC9A08AF5" modified="2011-01-11" version="1">MILPSPRIKRLLILVFFSFLIGNALLYLLLPYDNPLVLAFRFNFSGLQLWFRGSGVEKDAWLYKPAKYPIEYDTDVGLLIKTGYGTRHRLAAQLEALGLTAEDASSFVVVGDWTPRGGGKMAGVDVHDAIGGVMAMPEMRSHHDAPTFKTYLALKEAVQDGDDAKATEVGKRFGWDLDALKFIWGLEYVYDNLPPKKWYVILDDDTYLVRSSLRLLLAHWNWDTPQYIGNAVGDFKGRFAHGGSAVVISHEAARQLLSRRDVVAEMQEHSLDETWGDKLIAAALQKIGVYLDERYSHYFNGERPSISKIMADRFCSPLVSFHGVADPEEMKRIGAAFRDERSPVFWGQLWEIYGAPSIGDFKRSPIRADRDFVGRTDERARVLPATESGEACLEECEALADKCMAWTWVEQSRECRLSPWMILGEPVQGHFSGINVEEVEKLQALC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3R056</accession>
    <name>E3R056_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">General alpha-glucoside permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_11639</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697427">
        <property type="protein sequence ID" value="EFQ36494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100514.1">
        <property type="nucleotide sequence ID" value="XM_008102323.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R056"/>
    <dbReference type="GeneID" id="24417003"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11639"/>
    <dbReference type="eggNOG" id="KOG0637">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018303_1_1_1"/>
    <dbReference type="OrthoDB" id="28755at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008506">
        <property type="term" value="F:sucrose:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19432:SF35">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 45 MEMBER 3 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19432">
        <property type="entry name" value="SUGAR TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="223"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="283"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="337"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="369"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="396"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="439"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ36494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="467" mass="50120" checksum="2C04BE345ED6E448" modified="2011-01-11" version="1" fragment="single">MASPVEEPCFSPTESPPCEEHGQLLFEPEEPYELNPPERLSTPGLLLLTCPSLGLQVCWFLLQSSGTPYLHSLGMTSSSISLAWALGPIFGAFVQPIIGQLSDELHHPRGRRKPAIIAGALITVIFALIMACASELTTPFTKAQAVNPWQPRALAVACLVVILLALTAYSVGVRAIVVDTCPPSQQPAAAAWSMRWNVLGSTVLSIAGFVFTTQPPGTDPVVAFRTLVCVAAICSAATVGLVCWFVPRDATPPPRHFGSGIWRVCAMCLPGELARRWGRLPPLTGRVCSVQFVAWFGWFPVLYYMSTYAYETALFELLETPSLEASSPEASAKPYPLYASLSFSIGTLSSTLVLTLLSQTSAILRTRNLPRLWLLSQLLATTSLLLTIPFQTSTASLILISFIGVTQAVTMWVPFALVNTELAEVRTGVAGVQGLHNMAISLPQVASALICAVLLAGLDLLGVERDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3R169</accession>
    <name>E3R169_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NUDIX domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_12003</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697713">
        <property type="protein sequence ID" value="EFQ36857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100877.1">
        <property type="nucleotide sequence ID" value="XM_008102686.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R169"/>
    <dbReference type="STRING" id="645133.E3R169"/>
    <dbReference type="GeneID" id="24417366"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_12003"/>
    <dbReference type="eggNOG" id="ENOG502T67V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1184937_0_0_1"/>
    <dbReference type="OrthoDB" id="4823621at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003181147" evidence="1">
        <location>
            <begin position="22"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="198" mass="21982" checksum="40AC42F68FF27D33" modified="2011-01-11" version="1">MYSTTYAILFLVGLCRVLVGAQPLDVLAPREYKDWTNFKDINPWSLPEHYVKGTGDKAGSVYLGHERIRCGVVAFDGSTGIWMIPANNNFETVGYILPRGGYDIEKDKDMGDCVLREALEEGGLVISRSSLKPLGLSKGGSVFWFKGTVTKTVTPTEVRAHPPKLFSLTNAPKELQKPLKSPQKKEDMRMAFSVAERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q1Y0</accession>
    <name>E3Q1Y0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_00225</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089101.1">
        <property type="nucleotide sequence ID" value="XM_008090910.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q1Y0"/>
    <dbReference type="STRING" id="645133.E3Q1Y0"/>
    <dbReference type="GeneID" id="24405590"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00225"/>
    <dbReference type="eggNOG" id="ENOG502SJS3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018354_10_1_1"/>
    <dbReference type="OrthoDB" id="407275at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF39">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179293" evidence="6">
        <location>
            <begin position="22"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ25081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="454" mass="49171" checksum="242BC2F06FFD65F1" modified="2011-01-11" version="1">MDSKHFLRRFFVASLLCLTSAHILDQSNSKASELQTCLTTAGVRNAISTDDTWANDTAGFQKRIKVDPAAISFPENNDQIALSLDCARNASTSASVLGAAHSFQAYAWLPSTLSLDAATNRLTYGGGFHVGPVLKYLWDKHGRHFPHVRGANVGLAGSSIGGGFGSTSRHLGIPMDNLKSVEYMLYNVTIVNAPKGSDIFWAAQGAGASFGVLLSVITNTYKPVFDTAVNFTINAGDLTSTKAVKSLIAIQRYSLSKDCTDELALRWSLSGPPYMANGFFYGDAAGFDTVIAPLLRSLNDIAGSVTVQKTELPFWDMEVAVAGAGMNQPNESALSGRSFYTQSLTTTTDRPLTVEQAKVLYESTSFSFNRTDMRKSGFIDLWGDVSRDISDTDTSFAHGKNLWLIRWDFNSVDVNSYPADGPAYMKSLIKPFEEALVASGAPLRGFVNYADTEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q338</accession>
    <name>E3Q338_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_00161</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089037.1">
        <property type="nucleotide sequence ID" value="XM_008090846.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q338"/>
    <dbReference type="STRING" id="645133.E3Q338"/>
    <dbReference type="GeneID" id="24405526"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00161"/>
    <dbReference type="eggNOG" id="ENOG502SJ6A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024934_0_2_1"/>
    <dbReference type="OrthoDB" id="416217at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053157">
        <property type="entry name" value="Sterol_Uptake_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47784">
        <property type="entry name" value="STEROL UPTAKE CONTROL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47784:SF5">
        <property type="entry name" value="STEROL UPTAKE CONTROL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00755">
        <property type="entry name" value="AFLATOXINBRP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="85"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ25017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="468" mass="50772" checksum="EFC68106B2932E55" modified="2011-01-11" version="1">MDGSGGSSSAPGSTPTATATTPSAGATLSVAVPQGSISASSAASPSTITPAAATAGRGVGTPGAAIAAAGAAVVSRRSHPKSRTGCRTCKNRKIKCDEHKPSCRNCIKHAVPCDFLQSQRHSSSSSIPRSPDSIISSGGADNGHGFGDGLGGGGAGAGGGMSDLSLNLIDLELMHNFTTFAFNTLSTDPVVRQMWKVPVVKLALECDYVMRALLSVSALHLAHNRPEKRDFFISRALTYHQMASRTAMGLMGALDGENCEKLYLFSVLTIFFALACPRKSSDSLIMGESSFPDWIFLLRGTQSLLKLLQPQAYTGALLPMFNHGHERFLHSREESRAESELLVDLQRLVNKTCADPVLLPIYNRAIDELRRTLSVFLWDGGRGMDITDAFLWKYHMAEDFLPLLKVPGATQEAVAIFSHFCILLKRLENEWWLQGWATHLISRAWSLLDQDHRLWIQWPIEELGWVPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q382</accession>
    <name>E3Q382_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Enoyl-CoA hydratase/isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_00205</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089081.1">
        <property type="nucleotide sequence ID" value="XM_008090890.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q382"/>
    <dbReference type="STRING" id="645133.E3Q382"/>
    <dbReference type="GeneID" id="24405570"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00205"/>
    <dbReference type="eggNOG" id="KOG0016">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_6_2_1"/>
    <dbReference type="OrthoDB" id="448450at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005782">
        <property type="term" value="C:peroxisomal matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004165">
        <property type="term" value="F:delta(3)-delta(2)-enoyl-CoA isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000048">
        <property type="entry name" value="3,2-trans-enoyl-CoA isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051053">
        <property type="entry name" value="ECH/Chromodomain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43684">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43684:SF1">
        <property type="entry name" value="ENOYL-COA DELTA ISOMERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ25061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="273" mass="30168" checksum="CCD43FBD16257803" modified="2011-01-11" version="1">MASLEDSVISLEYRGRVALLTIDNDRKLNALAQMQYYDLAQKLREIATHDEVFITVLTAKGRYFSAGADVTIARTAPDGPDAHRHWLQSFVAFNLNITQAFYSHPKVLVVGLNGPVVGLSAALVAFADFVYATPATFLLTPFSSIGLVAEGGASRALVQRLGVGKANEALIMSKRITAEELLHVGFVNKVFDTGRGEDARFRELVLREVDERLGDHLIGESLTGIKALIRRPEMDVMDRQNSLEVFAGLERFLKGVPQEEFRKLASGEKRHKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3A3</accession>
    <name>E3Q3A3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Actin-related protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_00649</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="10">Component of the NuA4 histone acetyltransferase complex, of the INO80 chromatin remodeling complex, and of the SWR1 chromatin remodeling complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the actin family. ARP4 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089525.1">
        <property type="nucleotide sequence ID" value="XM_008091334.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3A3"/>
    <dbReference type="STRING" id="645133.E3Q3A3"/>
    <dbReference type="GeneID" id="24406014"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00649"/>
    <dbReference type="eggNOG" id="KOG0679">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027965_6_2_1"/>
    <dbReference type="OrthoDB" id="5132116at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13395">
        <property type="entry name" value="ASKHA_NBD_Arp4_ACTL6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000137">
        <property type="entry name" value="Actin-related protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004001">
        <property type="entry name" value="Actin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00432">
        <property type="entry name" value="ACTINS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0010">Activator</keyword>
    <keyword evidence="3" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00041020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ25505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="474" mass="52603" checksum="4CBEE595F188C8BE" modified="2011-01-11" version="1">MSQQPLSSSLQPTDIYGGDEVSALVLDPGYCTTRAGFAGEDVPKSVFPSFYGRVGSSDAPTTVFGDECLIPRADLEVRNYMSRDSVVEDWDVASKLWEHMLITRLQPARPTPPSKNGLNDDPKEEVEGTANGDVDMAMEDVETQEKALQENPLLMTEAPWNNAKSREKAIEIIMENWGCPAFWLSRTPVLAAFAAGKASALVIDVGGSSTSVTAIHDGMVLKRSIQKSPVGGLWLSSQIRSLWETSEPKIDPIPTFMVENKTPVDAGAPPQFKQRQFGFSITDSFRAYEDERLITEFKESVVETWRGPGKYSMPQNEDFAKTQPGRVFEFPNGANQMWREQRYKVSEGMWDETAAFPTNSEEFRLNKSQTIPELIRAALNAVDVDLRPNLLGNIVVTGSTSLLNGFNDRLNNELTAMYPGLKIKIHAAGLSSERRFGAWIGGSILASLGTFHQMWISRKEYEENGVSIVEKRCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3B0</accession>
    <name>E3Q3B0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Histone deacetylase interacting</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_00656</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089532.1">
        <property type="nucleotide sequence ID" value="XM_008091341.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3Q3B0"/>
    <dbReference type="GeneID" id="24406021"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00656"/>
    <dbReference type="eggNOG" id="KOG4204">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001360_2_4_1"/>
    <dbReference type="OrthoDB" id="10265969at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033698">
        <property type="term" value="C:Rpd3L complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010628">
        <property type="term" value="P:positive regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1160.11:FF:000001">
        <property type="entry name" value="Paired amphipathic helix protein Sin3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1160.11:FF:000002">
        <property type="entry name" value="Paired amphipathic helix protein SIN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1160.11:FF:000003">
        <property type="entry name" value="Paired amphipathic helix SIN3-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1160.11">
        <property type="entry name" value="Paired amphipathic helix"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013194">
        <property type="entry name" value="HDAC_interact_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003822">
        <property type="entry name" value="PAH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036600">
        <property type="entry name" value="PAH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039774">
        <property type="entry name" value="Sin3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031693">
        <property type="entry name" value="Sin3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12346:SF0">
        <property type="entry name" value="SIN3A, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12346">
        <property type="entry name" value="SIN3B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02671">
        <property type="entry name" value="PAH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08295">
        <property type="entry name" value="Sin3_corepress"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16879">
        <property type="entry name" value="Sin3a_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00761">
        <property type="entry name" value="HDAC_interact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47762">
        <property type="entry name" value="PAH2 domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51477">
        <property type="entry name" value="PAH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Histone deacetylase interacting" evidence="9">
        <location>
            <begin position="718"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="73"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="310"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="503"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1006"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="84"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="160"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="193"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="353"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="369"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="397"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="518"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="569"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1008"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1073"/>
            <end position="1082"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ25512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1480" mass="164638" checksum="F7AF841917803075" modified="2011-01-11" version="1">MMSGKPADEADAYEREAENRRRLVQEADEMERREQEQADRRRREGYPPGPPHHSNAGSIPIHQPVASRAMGAIHSPGGLLANHGSGSSGPPMPLGAPSGPGANFGGPLQPDNSRPPQHGGPNNPNAQHQMFAPIPHTTVPPSNSLGAASGGPPVFGGPLQQRDGQQPMQQGLYGGGGGSSGSGTAGAAGGQGQTQQQAQGGIAHGQQPILNDALTYLDQVKVQFHDQPDVYNRFLDIMKDFKSQAIDTPGVINRVSELFAGHPNLIQGFNTFLPPGYRIECGAGNDPNTIRVTTPMGTTVQSIAGRGTQVDAHAHPGGASQPLFPQRGNNWQQQQQQPPPPQQPQHSIESPEANFSTPVQNGPGSFGPAAQNLAAAFEAQGAAQQRGPPLQGAAHVNNGQQPPRNAHTPTPVTGPANVNGTANQQQQANMERRGPVEFNHAISYVNKIKNRFQDKPEIYKQFLEILQTYQREQKPIQDVYAQVTTLFHTAPDLLEDFKQFLPESAGQGKGTPGRPSDELPPGPGPNQTPQPSMSGQKMPPLGSFAPPSASKENSKKRPRTDKQTPIPVPAVVETAPPVNRAAPGAPPPAGANNKRTKLAHNKAITSDASAVEPTLTPILPEPLGPPTASTTNSDEIAFFEKVKKYLSNKTAFNEFLKVCNLFSQSIIDRNTVFHKGSVFFAANPELMGFWKAFLKYEPHEDVVDNRPAPPSGKVSLSNCRGYGPSYRLLPKRERLKPCSGRDELCNSVLNDDWASHPTWASEDSGFVAHRKNGFEEGLHRIEEERHDYDFNIEANLKCIQLLEPVAQQISVMSPLEREHFQMPQALAGHSTSVFKRVCKKIYGDKGPEVVNDLFTNPLNVVPIVLTRMKQKDEEWRFSQREWEKVWHAQVEHMHLKSLDHMGILVKQNDKRTLSAKHLVDVIKTKAEEQRRQRSLKGKAPRHQLVWDFSDKKVVVELLRLMMLYTVSSGQHSVPEKERISDFFETFIPAFFDIPEEEIDGRLPRLQDVSEEDDAEETVPTELTNGRSRRTGRRGDLLRGVLDPGRNGSKPRAHKEGSAASGSKETTPEVGSANEEEMPDAPEDGAGPDVSNERWMPIVPQPIVTTGDDALLTADGELKADGFFSRPWYNFFCNQTIFVFFNVFQTVYTRLRDVKESKESVIEEINRVNRPRPAKDIGLADNTLNYFGPNDDPSTFWPKTLELVEEYITGDIDEVRYQDVLRHYYLKSGWKLYTIQDLLKTLCRLALTCSSTDAKEKTPDLIQQYLHSREKEETNYQAEIAARKYAEKCVKDGEMFVICWFPQKSEAAVRWLQREDTTFYMDEMKAKDRWQYYISSFIQVEPTEGVPRHKLQKTVLARNLPSSDEKFEDSQIPKPISFDEDLSISICLNSSKMVWKAGTSEYFVYDNVPNDKESRERHLERLKNASNKRDTKLREKFVFNSPWMKGMNQADVQKLNEGWSKWLKEGTVPSSDVGDAMDTGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3J8</accession>
    <name>E3Q3J8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_00744</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089620.1">
        <property type="nucleotide sequence ID" value="XM_008091429.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3J8"/>
    <dbReference type="GeneID" id="24406109"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00744"/>
    <dbReference type="HOGENOM" id="CLU_2277286_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ25600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="102" mass="11234" checksum="D68F650D701224FA" modified="2011-01-11" version="1">MQSSYHEPFVLYATIPPTILTACFGCRASLLISAFDVLPRTPPKYCSKPLYEGVCLLPSLSQQEMRRLCVREVAVLPSGSAGWLVAKRSLNEYLRLGLVGST</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4C1</accession>
    <name>E3Q4C1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AMP-binding enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00577</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089453.1">
        <property type="nucleotide sequence ID" value="XM_008091262.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4C1"/>
    <dbReference type="STRING" id="645133.E3Q4C1"/>
    <dbReference type="GeneID" id="24405942"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00577"/>
    <dbReference type="eggNOG" id="KOG1176">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_11_1"/>
    <dbReference type="OrthoDB" id="2962993at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031956">
        <property type="term" value="F:medium-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05941">
        <property type="entry name" value="MCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201">
        <property type="entry name" value="ACYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201:SF28">
        <property type="entry name" value="ENZYME, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G01530)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="1">
        <location>
            <begin position="15"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="2">
        <location>
            <begin position="485"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ25433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="582" mass="63227" checksum="FC02143DEBC30E64" modified="2011-01-11" version="1">MASTASLPKLPLFEAISRHDPESTAVVHSLSGRRFKYGELLGDVRRARDKLLDSAGKQDLNGERIAFLVENSYDYVVTLLAAFAARSIAVPLSPAFPAPELQYILDQSEASLLVSSAKFATKAKEVLSAKLASNPTQVELQKHHGGSAHEQVELEDADVGAAGMMLYTSGTTNRPKGVLLPQSVLTAQSKSLIEAWNYSPKDHLLHVLPLHHIHGTVNAVLTPLLAGSTIEFMFPFNADAVWKRLAAPFIASNGVNDTNGANGTHALPKEKITFFTVVPTVYSRLLVTHKGLPLDPAEPTREAVSPRHMRLAISGSAALPTPIKESWKTLSKGNVLLERYGMTEVGMALSCGLDFADRVDGSVGWPLPGVEARLVDMDTGAVIPPGQDVDPETGRERPGEIQLRGPTVFKEYWRNPEATAKEFVEGEDGKGRWFKTGDIAVRRPVPNAGLNAAQSSWAKGDMYFIQGRKSADIIKTGGEKVSALEVERELLSLPEVAEAAVVAVPSGKWGSKVGAVVILNMDVVPHWSPMAMRRALRDRLVNYKIPQVLKVVDHIPRNAMGKINKKQLVQAVFEDQFSGDEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4J8</accession>
    <name>E3Q4J8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_01157</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ26013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090033.1">
        <property type="nucleotide sequence ID" value="XM_008091842.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4J8"/>
    <dbReference type="STRING" id="645133.E3Q4J8"/>
    <dbReference type="GeneID" id="24406522"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01157"/>
    <dbReference type="eggNOG" id="ENOG502SN6I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032417_0_0_1"/>
    <dbReference type="OrthoDB" id="1919336at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052360">
        <property type="entry name" value="Transcr_Regulatory_Proteins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206">
        <property type="entry name" value="ASPERCRYPTIN BIOSYNTHESIS CLUSTER-SPECIFIC TRANSCRIPTION REGULATOR ATNN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206:SF4">
        <property type="entry name" value="HYPOTHETICAL CONSERVED PROTEIN (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="55"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ26013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="463" mass="51838" checksum="2C6C5BFF246B7C9E" modified="2011-01-11" version="1">MDTRYQPKPQRSAAKVLPTLVPRPSEHAGGSGRDTLDRLALAKKTRSSKPKVRTGCKTCKIRRVKCDEARPICERCHKARIVCDGYDAPSTLGDTVAMKGKPKARPAGAPAPPAMADSLMTKSVFLLKETLRQYLSDSSAPPPVAQGPREEDVDDIEYMLSSLCLKGGWTPFLKAQKTNFVIWDASIHQVPDLGHRSAKQLQAEWSSFFARIMAFAGQALVKLSQERPISPDVVLLRQQQTYLRHVEKWRNVLDVNLARATAAGENHAKHAIRLMQLHHSMISINLRCCLDPTDMAWDEYDDEFSVLVERCLAFAIETKPAYHARFTLNMGNLSTIGPAIAKCRSHDIRMRALEVARRMPWREGAWDAAAEMFGRLGAVLLEERGRDTNGFISAENRWTWVDGDWDMEQRKLVGQYVRSVPDRDGNPVVTSLELGLDEWPDIYGDVSCFIDHSAGCRALETTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q587</accession>
    <name>E3Q587_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Quinate permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_00998</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089874.1">
        <property type="nucleotide sequence ID" value="XM_008091683.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q587"/>
    <dbReference type="STRING" id="645133.E3Q587"/>
    <dbReference type="GeneID" id="24406363"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00998"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_29_0_1"/>
    <dbReference type="OrthoDB" id="8120565at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF67">
        <property type="entry name" value="QUINATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14670)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="1"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ25854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="192" mass="21188" checksum="A20149A2A9AC7608" modified="2011-01-11" version="1">MAFIDKVGRKPILIGGSIVMLISMIIPGIIVAKFSYDWPGHPAEGWIAVAFIWIYIGAFGASWGPVSWTLISEIFPLSIRAKGASIGASSNWINNFAVAFYVPSMLKNWQWGTYIFFAVFLGGSIVWVWFCLPETKGVTLEEMDRVFGSNTAAEDTILLEQARRDVGLTEDLEDNAIQSEKKSLGESQLESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5R9</accession>
    <name>E3Q5R9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Multicopper oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_01311</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090187.1">
        <property type="nucleotide sequence ID" value="XM_008091996.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5R9"/>
    <dbReference type="STRING" id="645133.E3Q5R9"/>
    <dbReference type="GeneID" id="24406676"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01311"/>
    <dbReference type="eggNOG" id="KOG1263">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006504_7_1_1"/>
    <dbReference type="OrthoDB" id="10255118at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13857">
        <property type="entry name" value="CuRO_1_Diphenol_Ox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04205">
        <property type="entry name" value="CuRO_2_LCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13910">
        <property type="entry name" value="CuRO_3_MCO_like_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF414">
        <property type="entry name" value="ADR239WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0186">Copper</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="11">
        <location>
            <begin position="165"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="9">
        <location>
            <begin position="290"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="10">
        <location>
            <begin position="591"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="86"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="344"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="103"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="353"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ26167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="742" mass="82278" checksum="F19B4CE693246320" modified="2011-01-11" version="1">MSSGLVPRDGTGEEQHPMLGVRSFSDTDVEDRLLSDAAGFSEKDNYKRYAGHKKTFRWIMVLTCISILTLIPFIFAQFFNVQSKAQPSEPSHDEASEQQQESPPAPPPAPEPVPELTTSITPTTTLSLAPTQTPSVKLTPEQEFNLKTGFAISNMTSLREYVFNITRAQHSPDGFEKSMIKVNGQSPGPLIEANTGDTIRVTVHNHMLEESTTIHWHGIDQRNSVWMDGVQGITQCAIPPGESFTYEFNVTDQRGTFWWHAHVSVQVTDGLFGPLIIHDPDEQIPHIDDDKILMVGDLFHEYADTLLSQYLSATPPWAPKKPGREPPPDNVIINGMNTFNCSSVASHNAGDGKSSEEHSGHHMGDHNSARDSKCTGGSLFNTRIKSGSKARLRLINHGTSTPIVVTVDNHTLEIIEIDGVEVAPIATTRVYMNPGQRYSVIVNANQTAGNYLIRADAAIRCFHMSHKTNEAMSGMHGKPFGATAILSYDETDVGVAPIGKAWDLESKSNLQIGKEPWGKRCEDLPFDLPKPMRNRPAYDVGERNHHYFTFRQDRVGDVVRTHVNKTLYTPLKDDASLWKVLQQDITPENLNSPEPKLDFGQDQFVLVSQDNKAAQIVVNSDAMMVHPWHLHGQNFQVIGWGKGLFGATKTTWNFDNPMRRDTITIPGFSHIVIRILADNPGVWAFHCHYLWHAEAGMFVSIAQRMGELSNLLGTLDANGDIGAIKKKFCPTQNAQAAPAVPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6B4</accession>
    <name>E3Q6B4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">60S acidic ribosomal protein P0</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_01506</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. uL10 forms part of the P stalk that participates in recruiting G proteins to the ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090382.1">
        <property type="nucleotide sequence ID" value="XM_008092191.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6B4"/>
    <dbReference type="STRING" id="645133.E3Q6B4"/>
    <dbReference type="GeneID" id="24406871"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01506"/>
    <dbReference type="eggNOG" id="KOG0815">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053173_1_1_1"/>
    <dbReference type="OrthoDB" id="10259902at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd05795">
        <property type="entry name" value="Ribosomal_P0_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1730:FF:000002">
        <property type="entry name" value="60S acidic ribosomal protein P0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.105.20:FF:000001">
        <property type="entry name" value="60S acidic ribosomal protein P0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.105.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050323">
        <property type="entry name" value="Ribosomal_protein_uL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001790">
        <property type="entry name" value="Ribosomal_uL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040637">
        <property type="entry name" value="Ribosomal_uL10-like_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043164">
        <property type="entry name" value="Ribosomal_uL10-like_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_uL10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030670">
        <property type="entry name" value="uL10_eukaryotes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45699">
        <property type="entry name" value="60S ACIDIC RIBOSOMAL PROTEIN P0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45699:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00428">
        <property type="entry name" value="Ribosomal_60s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00466">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17777">
        <property type="entry name" value="RL10P_insert"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039087">
        <property type="entry name" value="L10E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="Ribosomal protein L10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL10-like insertion" evidence="7">
        <location>
            <begin position="109"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="278"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="293"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR039087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ26362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="313" mass="33464" checksum="2973E882860A2646" modified="2011-01-11" version="1">MGGKSANKAGYFDKLKGLLEEYKSIFIVTVDNVSSQQMHEIRQSLRGQGVVLMGKNTMVRRALKTFIPDSPEYERLLPFVKGNVGFVFTNGDLKDIRDKILANKVAAPARAGAVAPSDVWIPAGNTGMEPGKTSFFQALGVPTKIARGTIEIVSDLKLVEANSKVGPSEATLLNMLNISPFTYGMGIAQVYDQGNTFPASVLDIGEEQLLKAFAGAITTIAAVSLAINFPTLPSVIHSFFNGYKNVLAVAIETEISWPEIEELKDRIANPDAYAAAAPAAAAGGAAEAKEEAKEEEEKEEESDEDGGFGGLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6H7</accession>
    <name>E3Q6H7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nuclear architecture-related protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_01569</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the cytosolic Fe/S protein assembly machinery. Required for maturation of extramitochondrial Fe/S proteins. May play a role in the transfer of pre-assembled Fe/S clusters to target apoproteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NARF family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090445.1">
        <property type="nucleotide sequence ID" value="XM_008092254.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6H7"/>
    <dbReference type="STRING" id="645133.E3Q6H7"/>
    <dbReference type="GeneID" id="24406934"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01569"/>
    <dbReference type="eggNOG" id="KOG2439">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018240_0_1_1"/>
    <dbReference type="OrthoDB" id="10253113at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1780:FF:000004">
        <property type="entry name" value="Cytosolic Fe-S cluster assembly factor nar1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.950.10">
        <property type="entry name" value="Fe-only Hydrogenase (Larger Subunit), Chain L, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050340">
        <property type="entry name" value="Cytosolic_Fe-S_CAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009016">
        <property type="entry name" value="Fe_hydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004108">
        <property type="entry name" value="Fe_hydrogenase_lsu_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11615">
        <property type="entry name" value="NITRATE, FORMATE, IRON DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02906">
        <property type="entry name" value="Fe_hyd_lg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53920">
        <property type="entry name" value="Fe-only hydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Iron hydrogenase large subunit C-terminal" evidence="8">
        <location>
            <begin position="124"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ26425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="585" mass="62304" checksum="2DAC77652795BD84" modified="2011-01-11" version="1">MSAILSADDLNDFISPGVACIKPIETLPSAPPPSQDPSLEHEVILDGQPSSAAANAPPAEISLTDCLACSGCVTSAEAVLVSMQSHTEVLHTLDFGPALRIVGPDDDGQFRVDGLEDESRRLFVASVSPQTRASLAAAAGKGTTEKEAGHMLERLLGGPDGLASAGKHNNGFTWVLDTNVAREACLVLGADEVLSAEDAPASSATKPILTSSCPGWVCYAEKTHPYVLPHLSRVKSPQALMGTLLKTTLSKKLGIPPSRIWHLAVMPCFDKKLEASREELTDSVWAGDGMPGRGVRDVDCVITSKEVLMLAESRGFNFFDLARSKPSFERVFFPDARLDKFLFPGRIAHRSSQAAGTSGGNLYFTLQTVVSKHPGSQIQVVRGRNADVVEFIVASPAGDPIFKAARYYGFRNIQNLVRKLKPARPSRMPGGKAFGAARRPAGKSAGLEYAYVEVMACPGGCTNGGGQIKVDDPIIVERRGFEAKPGPLEQKVFLAEIDEAYFSAEDSDGEDGVSQNGGDLRADIVDGISPSYIRDTLAHWAGITGIDLGRMALTTYREVVSDVGKDKVSDTERVVQLAGKIGGGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6M6</accession>
    <name>E3Q6M6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">DNA replication complex GINS protein PSF1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_01618</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.</text>
    </comment>
    <comment type="function">
        <text evidence="1">The GINS complex plays an essential role in the initiation of DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the GINS complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the GINS1/PSF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090494.1">
        <property type="nucleotide sequence ID" value="XM_008092303.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6M6"/>
    <dbReference type="STRING" id="645133.E3Q6M6"/>
    <dbReference type="GeneID" id="24406983"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01618"/>
    <dbReference type="eggNOG" id="KOG3303">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079191_0_0_1"/>
    <dbReference type="OrthoDB" id="10252587at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071162">
        <property type="term" value="C:CMG complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000811">
        <property type="term" value="C:GINS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902983">
        <property type="term" value="P:DNA strand elongation involved in mitotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902975">
        <property type="term" value="P:mitotic DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd11710">
        <property type="entry name" value="GINS_A_psf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21696">
        <property type="entry name" value="GINS_B_Psf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1030:FF:000003">
        <property type="entry name" value="DNA replication complex GINS protein PSF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021151">
        <property type="entry name" value="GINS_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036224">
        <property type="entry name" value="GINS_bundle-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005339">
        <property type="entry name" value="GINS_Psf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056783">
        <property type="entry name" value="PSF1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12914:SF2">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN PSF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12914">
        <property type="entry name" value="PARTNER OF SLD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24997">
        <property type="entry name" value="PSF1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05916">
        <property type="entry name" value="Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158573">
        <property type="entry name" value="GINS helical bundle-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0235">DNA replication</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GINS subunit" evidence="9">
        <location>
            <begin position="46"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="DNA replication complex GINS protein PSF1 C-terminal" evidence="10">
        <location>
            <begin position="168"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="111"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU368085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF24997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ26474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="217" mass="24241" checksum="AD37E5CBE8206DA1" modified="2011-01-11" version="1">MYGDLGNKLVQHAKRTQNLAHLPAYQAEMVRAVTREVRDLDRDVTELLEPFQGSFDPSADQATACTVLVNYLSMRRNKRCLLAYHRTRSDKLEELAWRGIDVLDLSGQQVRGNAGSSTGGLNGNADGPTSSLSPQEEEYARQYGDLLAAYKGQWTDIDLTGSLEPPRDLFIDVRVLKDAGEIQTEYGAINLTKNSQFYVRQGDVERLIAQGYLQKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6P3</accession>
    <name>E3Q6P3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 18">Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial</fullName>
            <ecNumber evidence="5 18">1.3.5.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">GLRG_01635</name>
    </gene>
    <organism evidence="22">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18">Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>a quinone + succinate = fumarate + a quinol</text>
            <dbReference type="Rhea" id="RHEA:40523"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="18">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
        <text evidence="18">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="18">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
        <text evidence="18">Binds 1 [3Fe-4S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="18">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="18">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 18">Carbohydrate metabolism; tricarboxylic acid cycle; fumarate from succinate (eukaryal route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of complex II composed of four subunits: a flavoprotein (FP), an iron-sulfur protein (IP), and a cytochrome b composed of a large and a small subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 18">Mitochondrion inner membrane</location>
            <topology evidence="1 18">Peripheral membrane protein</topology>
            <orientation evidence="1 18">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 18">Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.1" evidence="5 18"/>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090511.1">
        <property type="nucleotide sequence ID" value="XM_008092320.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6P3"/>
    <dbReference type="STRING" id="645133.E3Q6P3"/>
    <dbReference type="GeneID" id="24407000"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01635"/>
    <dbReference type="eggNOG" id="KOG3049">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044838_0_0_1"/>
    <dbReference type="OrthoDB" id="1696654at2759"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER01006"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008177">
        <property type="term" value="F:succinate dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000007">
        <property type="entry name" value="Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1060.10:FF:000001">
        <property type="entry name" value="Succinate dehydrogenase iron-sulfur subunit SdhB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="entry name" value="Alpha-helical ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050573">
        <property type="entry name" value="SDH/FRD_Iron-Sulfur"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004489">
        <property type="entry name" value="Succ_DH/fum_Rdtase_Fe-S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025192">
        <property type="entry name" value="Succ_DH/fum_Rdtase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00384">
        <property type="entry name" value="dhsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004616">
        <property type="entry name" value="PRK05950.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11921:SF29">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE [UBIQUINONE] IRON-SULFUR SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11921">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE IRON-SULFUR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13085">
        <property type="entry name" value="Fer2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13183">
        <property type="entry name" value="Fer4_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46548">
        <property type="entry name" value="alpha-helical ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 18" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="16 18" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="8 18" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="14 18" id="KW-0408">Iron</keyword>
    <keyword evidence="15 18" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="18" id="KW-0472">Membrane</keyword>
    <keyword evidence="11 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="18" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <keyword evidence="9" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="19">
        <location>
            <begin position="46"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="20">
        <location>
            <begin position="181"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00049220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU361237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EFQ26491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="277" mass="31429" checksum="C533E20E53F93350" modified="2011-01-11" version="1">MASLRSSSRVLGSATKVAFRPAVTVPRRGLATASDRVPRTKEPEMKKFTIYRWNPDTPTEKPRMQEYTLDLNKTGPMMLDALIRIKNELDPTLTFRRSCREGICGSCAMNINGQNTLACLCRIPKESSSDIKVYPLPHTYVVKDLVPDLTQFYKQYRSIKPYLQRTTPAPDGKEYRQSVADRKKLSGLYECILCACCSTSCPSYWWNSEEYLGPAILLQSYRWLADSRDEKSAERKAALDNSMSLYRCHTILNCTRACPKGLNPGKAIAEIKKQMAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6W5</accession>
    <name>E3Q6W5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cyclin-like F-box</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_02423</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090623.1">
        <property type="nucleotide sequence ID" value="XM_008092432.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6W5"/>
    <dbReference type="GeneID" id="24407788"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02423"/>
    <dbReference type="eggNOG" id="ENOG502S02W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048311_0_0_1"/>
    <dbReference type="OrthoDB" id="4540290at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180171" description="Cyclin-like F-box" evidence="2">
        <location>
            <begin position="24"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ26603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="344" mass="35256" checksum="D50C608EF1358017" modified="2011-01-11" version="1">MLTVRSPTAALAVVLSLLSVVQGAPQNRKGNGNGRANRQTAQQQAAQVPQGISQATDGSVILDMTANVNGLDLRFKISGPADQFTAASGVPGAAAQAGAQGPLGINVLLHGDGGQSFFDMPNQGVQQNLAGVAILAPDPNLFWGGGQGLQRTDGVAHSQAVNDLIQKTLPQVMAFNQSNVFFTGVSGGSLMLSGFFMPAHIQNFAGNGVLLNCGGLPPQVDVQDAQAVAGTRIHFQSTLQELSSLQKAIPASIKAYEKIATGAGLSADQVNAKQTVNNSPNGGHCAFDEKGFVSGIQLVANNYATIMQGGNGEVQGIGNVLTGVTGNENLQFTGSSRARRGVIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q783</accession>
    <name>E3Q783_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6546 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_02541</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090741.1">
        <property type="nucleotide sequence ID" value="XM_008092550.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q783"/>
    <dbReference type="STRING" id="645133.E3Q783"/>
    <dbReference type="GeneID" id="24407906"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02541"/>
    <dbReference type="eggNOG" id="ENOG502SM97">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023464_2_1_1"/>
    <dbReference type="OrthoDB" id="4802432at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046676">
        <property type="entry name" value="DUF6546"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20183">
        <property type="entry name" value="DUF6546"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6546" evidence="2">
        <location>
            <begin position="263"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ26721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="531" mass="59872" checksum="7A4ADF84DD3E9B5C" modified="2011-01-11" version="1">MGDKTEMASWNGLPVELRGLILEHLAFSAVAERRSRIWKAKSKRHDMGSYAVVCRQWQGFIEKINFSNLEISTAKDLASFDEILQDPARRSYLRRVSLRVELPRYPNKLAKVPETDIEQNENEVAFTQGVWNFFDILSKWAPSASDFELELSAASPSDKNKYFGEMGLDQDGNSRFFDHDLDFCFITAGCDQIGRHGLPEVPVISSCQILRRNHRNFSSRALLTIFSSLPRLREVRFEPWHQVDMEAQLEVDSDHARSLPFWPSHIKRISIFEHFDAFADGGEGEWEDADSGEENEMEANPDPAAPGPAMAEADDLGDVPRTSCPSLGHNLGHLSLQAEEMAVSNVSDASDFFEGLISRNRSPPVWKHLRRLALTSNMMIDGVDAELINNVLRTAANAAKHMPALQILEIYKTDQFGGAVFRYSVDSLSTTASWEGTWDFRVEKDVKAAWAEVSKRNTAHDLDFMPEIHLGDYCGPYAFFDEHLKTKDLVLHPSSLEDMLSKKMDKCKACNGYCAHPKSAEQIWGSFGDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7C8</accession>
    <name>E3Q7C8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Mediator of RNA polymerase II transcription subunit 17</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 8">Mediator complex subunit 17</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MED17</name>
        <name evidence="10" type="ORF">GLRG_02586</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the Mediator complex subunit 17 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090786.1">
        <property type="nucleotide sequence ID" value="XM_008092595.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7C8"/>
    <dbReference type="STRING" id="645133.E3Q7C8"/>
    <dbReference type="GeneID" id="24407951"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02586"/>
    <dbReference type="eggNOG" id="ENOG502QS9H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015164_0_0_1"/>
    <dbReference type="OrthoDB" id="5319830at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070847">
        <property type="term" value="C:core mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019313">
        <property type="entry name" value="Mediator_Med17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13114">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13114:SF7">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10156">
        <property type="entry name" value="Med17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0010">Activator</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="39"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="515"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="515"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ26766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="659" mass="71556" checksum="71B4368C2D478D23" modified="2011-01-11" version="1">MASGSSMPFSSLHPVPTGGRKPKSLGEFIARVQSERGFRNVTEESLKEEVENQKNGDAEVKDEDTAMSDGNADDEEPPDAGAARMEVLRNIDVAQNAALMTLDFISLLLSKESPAQAGVTLSQALRDWTGIGTLGIAKREDSEEQKQRDADRAKDNRDVSLGWALLDIQTTKESADKAASHLSKEVEREAKYWDQVLAVHRAGWSMCRLPAERHTLGVRFGFSEASPEFRNSSLAPLRRGDDGTALLQHGRVGAGSQRLSITVSRSGETTGRLAIGSSVPDSAHLPDRVLEARNTIFAQELWHELHREAHSLASYGVRANNDSITFNPASGPSLTLELETLDGGAPAVGASTEDNVLAEATHLGLHILLSHAHRLNELQRLRPTPPHQRRNQTQSQYHLLRPIVAKILYDRSVEQVTSFAGDLTRVLRRAGVHAASFTLSTPPFPTADLKNTSGGASNRPNASQALTNMLTSPADFQVELTLTPTARLQIRGRTFLLPLTTTQFQLQLLPSIAEPTSAEPASSSLQASYPPSRDPYPDFPSVQRYVASAAAHALTDFAMSFIPATPANLSEPAHGEWSKSVRGTAIRDMDTETREIRFDVLSNDHEGRLTLQIGAAWRAGDKPLVKRWAWPAVGEGAGKSATQPHVGEIVAAVVQSKEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7N9</accession>
    <name>E3Q7N9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_02072</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ26901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090921.1">
        <property type="nucleotide sequence ID" value="XM_008092730.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7N9"/>
    <dbReference type="STRING" id="645133.E3Q7N9"/>
    <dbReference type="GeneID" id="24407437"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02072"/>
    <dbReference type="eggNOG" id="ENOG502RIXM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047025_0_0_1"/>
    <dbReference type="OrthoDB" id="3509362at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF15">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ26901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="331" mass="36615" checksum="723D1FEE5C210AF1" modified="2011-01-11" version="1">MSSGTQNPFLTHLTPMMIRSNALLFSISSMAAGHLAVLRDDESLHILSSRHMLMAVSSLRESIETEDPQLSLATILMLQISDRLFNTHSQIDHLAGAKAVIIHSGGLKGWTSSSAQFLLSLCFFHDVMSSVSRTSRPLLSMTNVAPLEGMQSLAKLTSLVSIVSTISKMQGQSGDAHQRRGLAIRESLERFSIVADGDPAIENTIQAYRHAALVYLCRVWSDGTSLPKPFHAGRCLHYLLQVPVTSSCVSAHAWPLWTAGCESIDPGQRGLVLERLKAMYENRHLPSLTRAQEDMEEVWKAKDAQRLQFGTENIDCCKVILDKRHREADLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7Z3</accession>
    <name>E3Q7Z3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02176</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091025.1">
        <property type="nucleotide sequence ID" value="XM_008092834.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7Z3"/>
    <dbReference type="STRING" id="645133.E3Q7Z3"/>
    <dbReference type="GeneID" id="24407541"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02176"/>
    <dbReference type="eggNOG" id="ENOG502SV8I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015463_1_0_1"/>
    <dbReference type="OrthoDB" id="2129362at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="463" mass="53441" checksum="2139F3CC81F9F30C" modified="2011-01-11" version="1">MNVSVHDEATSSHGDGSSRFSNSFDKTVDSVSMEPISGFFHNWIDTLSSDCVTSFLDEVENHHNHDVDTTNGQLLEKIEQPDTIVNIEEEALMKPAMLHRRRDWTSNLVIHREIAIRKGLMRRQQEEKKRERCSLPAQDTQGWEPKENRHYINIRRESISNDKKLLVDCVLRPVRLEDAIGCAEAYNAAVADHDHQAVDTSPVSAERFEFIIRECMYEKLPFVVATKQKVDLSDAKNWPSLDAYRQYMRWRQSQPEEDKPTEHNICGFAFLRPYERGICGLSGTACLAVKATVFVRPDRRRGGIGSALIRQILTQTSILYYGNGAKYKWEDPNHGDDSFRTSGFRNVHRIIFHTMDKRESNQSLKWMDNFMASLQFEKSGRISQVYRVDTPHGVEWYDQIIWQHWANKIDSVRTLYMSDESECSYDYPGKPHAPDYQQVQLPPVVGEELGYGSDRDSDDVFGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8E2</accession>
    <name>E3Q8E2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">PH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_02325</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091174.1">
        <property type="nucleotide sequence ID" value="XM_008092983.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3Q8E2"/>
    <dbReference type="GeneID" id="24407690"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02325"/>
    <dbReference type="eggNOG" id="ENOG502REBM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002541_1_0_1"/>
    <dbReference type="OrthoDB" id="2123378at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13278">
        <property type="entry name" value="PH_Bud4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000311">
        <property type="entry name" value="GTP binding protein (Bud4)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012966">
        <property type="entry name" value="AHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052007">
        <property type="entry name" value="Bud4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36100">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36100:SF1">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08174">
        <property type="entry name" value="Anillin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="5">
        <location>
            <begin position="1342"/>
            <end position="1463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="124"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="957"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="1197"/>
            <end position="1225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="48"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="179"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="192"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="284"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="308"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="365"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="438"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="475"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="491"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="539"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="569"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="685"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="715"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="726"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="777"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="804"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="826"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="957"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1010"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1022"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1045"/>
            <end position="1054"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ27154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1509" mass="167703" checksum="20311E6283F1915B" modified="2011-01-11" version="1">MASSEEPVHPLRISKGSSNPGSPPTAKANTGIPRPLSELSPSDHRRNSPSWKQPSKKMTLNTDSSPFQSSPLETTTSPRLFWQKRNLDSISTENAGLYGGRHGSPSPTRRTSIERLQKASRVKNSNILALEQKQEYDPTRLPQVERPLAKHQGSSFDGTTTIINGLRSSDSLSRGVGHQRNNSKSSIPIYNPAASPTKPSTPTQAGPSNPPRSPGKDQASPMKSSLSRSHFKSSFDHETGTWSDDTSFDDRELPSGKSLHRHAKSVTFDAAPPQINEYEMATPDISSIGSNSREGSFDSMDDEDDEEGHYHFGEHDIEGDSFDASLEDTDKTPVVGPDDWRQSAERVEEDPFDGSPMPDTLPRLGRTEHKRSDSSTSDHRPLPPLPGMGSPARSDSRSSPGLSATAERMLSAHRSLPSPPPAAASKSEIQSIGNGKMTLEERLKLMMLSDDHKSANEQQRERRLRRGATRDRIQSPASDTETAESSMLSLDADEADEADDTIGDISALENYELPSRISRESIMRRVNGGNSDQGGDYFSSPAPSSSPERPGPEHRLDLPLDPDVPIPSTEDDSILDDISELSDEGSVIIHRDEPSDAETESITHFYARSDIDDNDTDSASHYSDGPARVPEVTQVEDDILTPRAAKSFGMASEVRPLELKSDRAGNVSDQQVDVVAEASAKEPTPEDEMTQVFEPEVETQPEAEAQLEAEKEPSPEAQAAAPVDAPAEREHSLPEMKDESRDNEFSRGLQSFMLAPPPEPSAKELEDLQPPPKMTDLQAQTQRPSTPKQFQLSKPDYDGSGWGDPEDEYEEEPGTPESVIHRPMSSDEEEEESEIFDEPPMESPAIPERQATIKASGSKLKTRPSNTPSDIIAMREARRQVSREVPDIPVIPERHRNRLSRDLQEEPGIDEDFVMKRHSSFAKRSLTLDLDFGLSLDQDFDRVIEAQKVAISHQVHNSSHFASGGPSRQASRPAATTSKLGSVEEKLQNANKKNQRGYLMRQNTKVVTASDKESSDMWKSRSAGNSPVKTDRPQSWTVEPWNGRPRQKSVRRRPQTSGPVPPMPGQESNAQALNPLTEEDLNPELATEESGERGRLFVKVLGVKDLDLPIPRTERTWFSLTLDNGVHCVTTAWLELARNAPVGQEFELVVPNELEFQLTLNVKLEKPPPKKVTVQSPTKAIKPKTSTFSRVFASPKKRKEMEMRQREEEERLAAEQQKAAQARQVKVAPTAWDLLSPLAAEDGSFARSYVCLKEHESRCYGRPYVVDVACFNEWATEEAAFASSVKSKRGNTAVVRRAPYKIGKLELQLLFVPRPKGSTEEDMPKSMNSCIRELKAAEERLAKNWEGHLSQQGGDCPYWRRRYFKLVGHKLTAYHEATRQPRATINLANAKRLIDDRRALTEKETTGKGGRRRRSAFAEEEEGYMFVEEGFRIRFNNGETIDFYADTAEDKAGWLAALTDLVGRGDSDDEVGGPRKQGKWCELVLKREEALRRRAEGRRVHSRTKSTFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8L4</accession>
    <name>E3Q8L4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_02056</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ26885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090905.1">
        <property type="nucleotide sequence ID" value="XM_008092714.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8L4"/>
    <dbReference type="GeneID" id="24407421"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02056"/>
    <dbReference type="HOGENOM" id="CLU_2775785_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ26885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="69" mass="7649" checksum="CA97E684D4A1CA97" modified="2011-01-11" version="1">MDVARKVTRDAPFLSKRVPGRLLALAGGDGQWPHIVCANALQVVVRPGVQLDVRYCPRQIRQYVCFGEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8X4</accession>
    <name>E3Q8X4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Trehalose-6-phosphate synthase</fullName>
            <ecNumber evidence="6">2.4.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">UDP-glucose-glucosephosphate glucosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_01983</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>D-glucose 6-phosphate + UDP-alpha-D-glucose = alpha,alpha-trehalose 6-phosphate + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18889"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58429"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="2.4.1.15"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the glycosyltransferase 20 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.15" evidence="6"/>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091508.1">
        <property type="nucleotide sequence ID" value="XM_008093317.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8X4"/>
    <dbReference type="STRING" id="645133.E3Q8X4"/>
    <dbReference type="GeneID" id="24407348"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01983"/>
    <dbReference type="eggNOG" id="KOG1050">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002351_7_2_1"/>
    <dbReference type="OrthoDB" id="755951at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005946">
        <property type="term" value="C:alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003825">
        <property type="term" value="F:alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004805">
        <property type="term" value="F:trehalose-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034605">
        <property type="term" value="P:cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005992">
        <property type="term" value="P:trehalose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd03788">
        <property type="entry name" value="GT20_TPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000007">
        <property type="entry name" value="Trehalose-6-phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000035">
        <property type="entry name" value="Trehalose-6-phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001830">
        <property type="entry name" value="Glyco_trans_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012766">
        <property type="entry name" value="Trehalose_OtsA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02400">
        <property type="entry name" value="trehalose_OtsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788:SF106">
        <property type="entry name" value="BCDNA.GH08860"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788">
        <property type="entry name" value="TREHALOSE-6-PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00982">
        <property type="entry name" value="Glyco_transf_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 8" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="507"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="513"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ27488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="532" mass="59829" checksum="3FC4F020E3EFB034" modified="2011-01-11" version="1">MPALVDEDTAPGRLLLLSNRLPITIKRSEDGSYSFSMSSGGLVTGLSGLSKTTSFQWYGWPGLEVPENEIAGMKQRLKDEYDAHPVFIDDELADKHYNGFSNSILWPLFHYHPGEITFDESAWAAYREVNRLFAKAVVQDVQDGDLIWVHDYHLMLLPEMLREEIGNTKKNVKIGFFLHTPFPSSEIYRILPVREALLTGVLDCDLIGFHTYDYARHFLSSCSRILGTPTTPNGVDYNGKFVTVGAFPIGIDPEKFVEGLKKPKVQERIEALTRKFNGVKLIVGVDRLDYIKGVPQKLHALEVFLTEHPEWIGKIVLVQVAVPSRQDVEEYQNLRAVVNELVGRINGKFGTIEFMPIHFLHQSVSFDELTALYAVSDVCLVSSTRDGMNLVSYEYIATQRERHGVMILSEFTGAAQSLNGSLIVNPWNTEELANAIHDAVTMSPEQRETNYKKLERYVFKYTSSWWGQSFVAEMTRLSQETVQPKTLRNISGNVVGQVTKALQGAIEGASRTAGKDGAEETKQETKQENQEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q919</accession>
    <name>E3Q919_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">3'-5' exonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_02028</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the exosome component 10/RRP6 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091553.1">
        <property type="nucleotide sequence ID" value="XM_008093362.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q919"/>
    <dbReference type="STRING" id="645133.E3Q919"/>
    <dbReference type="GeneID" id="24407393"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02028"/>
    <dbReference type="eggNOG" id="KOG2206">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010129_0_0_1"/>
    <dbReference type="OrthoDB" id="2250022at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003727">
        <property type="term" value="F:single-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071044">
        <property type="term" value="P:histone mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071040">
        <property type="term" value="P:nuclear polyadenylation-dependent antisense transcript catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071039">
        <property type="term" value="P:nuclear polyadenylation-dependent CUT catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071036">
        <property type="term" value="P:nuclear polyadenylation-dependent snoRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071037">
        <property type="term" value="P:nuclear polyadenylation-dependent snRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071051">
        <property type="term" value="P:poly(A)-dependent snoRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06147">
        <property type="entry name" value="Rrp6p_like_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000059">
        <property type="entry name" value="Exosome complex exonuclease Rrp6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.80">
        <property type="entry name" value="HRDC domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012588">
        <property type="entry name" value="Exosome-assoc_fac_Rrp6_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002121">
        <property type="entry name" value="HRDC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044876">
        <property type="entry name" value="HRDC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045092">
        <property type="entry name" value="Rrp6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049559">
        <property type="entry name" value="Rrp6p-like_exo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12124:SF47">
        <property type="entry name" value="EXOSOME COMPONENT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12124">
        <property type="entry name" value="POLYMYOSITIS/SCLERODERMA AUTOANTIGEN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00570">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08066">
        <property type="entry name" value="PMC2NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00474">
        <property type="entry name" value="35EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00341">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="HRDC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50967">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5" id="KW-0271">Exosome</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="HRDC" evidence="10">
        <location>
            <begin position="446"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="625"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="760"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="655"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="679"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="765"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="800"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="873"/>
            <end position="882"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00043957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ27533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="882" mass="98472" checksum="F8A550FE8D3E8A79" modified="2011-01-11" version="1">MTSPQDFKSLQDKVQAALLATVKSVNRVSAEDLPFQRAVNPNIGEDLDAKTTRILELSTSLLKSAADVCGLNAPELEDADDVDMRWRSIVDIVDSVLEKADTSIDEYTGALKRKDAPATDATPQSKKPKTTGTVIRSANITKPQLHFTRIVDNNTTWKPIITEKPHATVPLEKSLVTSETDDGFIQYKHPYETEILEAKYPDRVYEQAEPIPWQPVETTEATYVDTYEGVLEMLEDLKKANEIAVDLEHHDFRTYVGLTSLMQISTREKDWIVDTLKPWREQLQVLNEVFADPSIIKVFHGAFMDMVWLQRDLGLYVNGLFDTGMACEVLHYPQKSLAFLLKKFVNFDADKKYQLADWRVRPLSEEMLYYARSDTHYLLYIYDKMRNELVMKSDRGNPSTDYIEATLQKSKTLSLSRYGGETFDPKTGKGNKGWYNTLLRHPMPFSGQQFAVYRAIWAWRDEVARREDESTPFVMPNAIIGDIAKHMPPDAKALHALIPNHAFIARRNVTEIWKRYQEAREQGINEPRLLDFFKSELPKAATKPLAEIVSEDAADAALEPTELTQSQLFGGMPLSTAWEKAAAAANGLGEYVTFPWQKFVQNAKAVDAAAQEDVAMQGGVEAEAKAAAAAQPKEPEVDEEFTLKAGTKRKVPTEDVSDASDDSDSGASSIDIVLEKPGSGKKGKKGKHTSTESKAMVASKRADKVARYTEEYEKAKAEVERLTELIAHDGADATQLEEAEGIAADKQEKLERYVSALNNRKAKAERKAAKKAEKAKKEAEKAEKEAEKETKKAARRAAKKAKEDAKKAEEENAAAESGDSDEEETFDYSKATSVLHANRTGNRGKVNVKPTFDPYAKTGDDAPKGARKAVPPRGERTATFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q937</accession>
    <name>E3Q937_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="9">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_01711</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="9"/>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091236.1">
        <property type="nucleotide sequence ID" value="XM_008093045.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q937"/>
    <dbReference type="STRING" id="645133.E3Q937"/>
    <dbReference type="GeneID" id="24407076"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01711"/>
    <dbReference type="eggNOG" id="KOG2204">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003818_0_0_1"/>
    <dbReference type="OrthoDB" id="8118055at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.10:FF:000037">
        <property type="entry name" value="alpha-1,2-Mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF89">
        <property type="entry name" value="ALPHA-1,2-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="313"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="426"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="471"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="558"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="383"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ27216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="568" mass="64506" checksum="4AB238997408D901" modified="2011-01-11" version="1">MANRRQRRVIIIAVFLLGILVFHNFRSSVSPPPRQHADIRLVKSSFDWANHQHKYPVAPSSMHRLPTERPKALPQVQFDFSTKRIHKNDATSESRRQAVRDVFVKSWNSYKEYAWGFDELAPITAKGKNTFGGYAATLVDALDTLWMMDLRDDFEAALPVIGSMDWDNTKETAVNVFETTIRHLGGLLSAYDLSGEPVLLSKAIELGDMLYASFDTPNRMPPFWLDFEAAKAGNLVAGTADPSASPCSLSLEFTRLSQLTGDPKYFDAIERIKRFLEKTQRESQLPGMWPALINFRDQSVTQHNEFTLGALADSLYEYLPKMFALLGGTDPAYERMYRQAMRVVEEHLLFRPMLPDGEDILFSGSAVVEGNVRRNPESQHLACFTGGMFGLGGKLFGIKEHMSIAERLARGCGWAYSSFPTGVMPEIFGMVTCETLDGCEWDEDRWKREGASDLRKGFSNARDPRYILRPEAIESIFLMYRMTGNPEYQEIAWTMFQSVVKATETQHANSAIEDVTVKGETRKLDSMESFWLAETLKYFYLIFSPPSLISLDEYVLNTEAHPLRRQLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9B7</accession>
    <name>E3Q9B7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_01791</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091316.1">
        <property type="nucleotide sequence ID" value="XM_008093125.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9B7"/>
    <dbReference type="GeneID" id="24407156"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01791"/>
    <dbReference type="eggNOG" id="ENOG502QVDR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038276_0_0_1"/>
    <dbReference type="OrthoDB" id="4084551at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028000">
        <property type="entry name" value="Pma1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14610">
        <property type="entry name" value="Psg1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005673307" evidence="3">
        <location>
            <begin position="27"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="242"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ27296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="329" mass="35464" checksum="04711A4A56A808CD" modified="2011-01-11" version="1">MFGTIQRTWLSTLAATSLFLASITSADVQPRQGDIPVNDWITIDSSGRARTITPSVVTSNGALTTISPPPYSLTGSVYTVTATGGGLTTSTGAPPPPKASNARGYGGAFPVCNNRVGNDSPFCFPRRGNTLHVESTYYITWDTTFFADPATPIVIIGFDVDNGVTDSAPAFSVTNLNGGDGWLPWTPRVKDLEGRKSNNMTIFLVYSDPLTGREMNKTGPVFTLQAALGTEAFSTRPDLLPILLPVILISLAIATVMLWLYIRRHRRHAAAAAAAEHRNATYVPGHTRGMYGQKGSADIMLGPTSPPLGEPPGRNVFQDELRRQERERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QA30</accession>
    <name>E3QA30_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cupin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_02862</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the germin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091738.1">
        <property type="nucleotide sequence ID" value="XM_008093547.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QA30"/>
    <dbReference type="STRING" id="645133.E3QA30"/>
    <dbReference type="GeneID" id="24408227"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02862"/>
    <dbReference type="eggNOG" id="ENOG502SINP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061239_3_0_1"/>
    <dbReference type="OrthoDB" id="1921208at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02241">
        <property type="entry name" value="cupin_OxOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006045">
        <property type="entry name" value="Cupin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001929">
        <property type="entry name" value="Germin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019780">
        <property type="entry name" value="Germin_Mn-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31238">
        <property type="entry name" value="GERMIN-LIKE PROTEIN SUBFAMILY 3 MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00190">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00835">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00725">
        <property type="entry name" value="GERMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180268" evidence="6">
        <location>
            <begin position="21"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin type-1" evidence="7">
        <location>
            <begin position="70"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ27718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="253" mass="26613" checksum="792AA60EEDD1C58F" modified="2011-01-11" version="1">MHFTPAAAATILALASSAFAAPYSSTSPPAQTSTAAPAPASTLSLTQQLFLSDTAADRFKLLPDDKQFVFDFNQPQNNPGKGGELIAANRKTFPALVGTGSGMAVGRVGPCGMNTLHVHPRSAELQIVVEGRLITEMTPENGVVEAADGKTRRVITTELGPFQMTPFYQGSIHSQFNPDCDDAVFVASFAAEDFGTGQVADSTFAFSDDLIAATFGQSIAGADIDRVRKAIPASIALGVDECLKKCNIKKRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>E3QA38</accession>
    <name>E3QA38_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Leucine carboxyl methyltransferase 1</fullName>
            <ecNumber evidence="3 8">2.1.1.233</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_02870</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>[phosphatase 2A protein]-C-terminal L-leucine + S-adenosyl-L-methionine = [phosphatase 2A protein]-C-terminal L-leucine methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:48544"/>
            <dbReference type="Rhea" id="RHEA-COMP:12134"/>
            <dbReference type="Rhea" id="RHEA-COMP:12135"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90516"/>
            <dbReference type="ChEBI" id="CHEBI:90517"/>
            <dbReference type="EC" id="2.1.1.233"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the methyltransferase superfamily. LCMT family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.233" evidence="3 8"/>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091746.1">
        <property type="nucleotide sequence ID" value="XM_008093555.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QA38"/>
    <dbReference type="STRING" id="645133.E3QA38"/>
    <dbReference type="GeneID" id="24408235"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02870"/>
    <dbReference type="eggNOG" id="KOG2918">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031312_1_1_1"/>
    <dbReference type="OrthoDB" id="203237at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018423">
        <property type="term" value="F:protein C-terminal leucine carboxyl O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016651">
        <property type="entry name" value="LCMT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007213">
        <property type="entry name" value="Ppm1/Ppm2/Tcmp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13600">
        <property type="entry name" value="LEUCINE CARBOXYL METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13600:SF21">
        <property type="entry name" value="LEUCINE CARBOXYL METHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04072">
        <property type="entry name" value="LCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016305">
        <property type="entry name" value="LCM_mtfrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 8 11" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="196"/>
            <end position="197"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR016305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR016305-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ27726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="359" mass="39878" checksum="5A80396A31D7C9E6" modified="2011-01-11" version="1">MSRDSIPNLLSLRGARGGRGGRGRGRGPGGPSSGPTHDQTIQGTDDDAAGSRLSAVNVGYLADPYAQFFVDNLAGPPPRRLPIINRGTYTRTVALDNLIDSFLDESDGTQSGSKQRQIISLGAGTDTRPFRLFPRANRPELVYHEIDFAVTVRKKARIVQSAPPLRQILGVPSVEEDGSWSSQPSSADKYYCHSRDLRELVQGGSQPLAGLRTDFPTLLISECCLCYLETSTAKDIVAWFEQKIPNLAIIIYEPVRPDDPFGKMMTSNLAARRIRMPTLESYKLPQHQTQRLRDAGFEHANTLTVERIWEKWVSAEEKERVDRLEGLDEVEEWKLLADHYVVAWGWRGVGFALDDSNGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>E3QA40</accession>
    <name>E3QA40_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">AP complex subunit sigma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_02872</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Adaptor protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type subunit APL3 and beta-type subunit APL1), a medium chain (mu-type subunit APM4) and a small adaptin (sigma-type subunit APS2).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <location evidence="2">Coated pit</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the adaptor complexes small subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091748.1">
        <property type="nucleotide sequence ID" value="XM_008093557.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QA40"/>
    <dbReference type="STRING" id="645133.E3QA40"/>
    <dbReference type="GeneID" id="24408237"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02872"/>
    <dbReference type="eggNOG" id="KOG0935">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061221_3_2_1"/>
    <dbReference type="OrthoDB" id="371463at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030122">
        <property type="term" value="C:AP-2 adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035615">
        <property type="term" value="F:clathrin adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072583">
        <property type="term" value="P:clathrin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd14833">
        <property type="entry name" value="AP2_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000011">
        <property type="entry name" value="AP complex subunit sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016635">
        <property type="entry name" value="AP_complex_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027156">
        <property type="entry name" value="APS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11753">
        <property type="entry name" value="ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015588">
        <property type="entry name" value="AP_complex_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0168">Coated pit</keyword>
    <keyword evidence="6" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AP complex mu/sigma subunit" evidence="13">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00062168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR015588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ27728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="143" mass="16858" checksum="E0FBC52B5E7501D8" modified="2011-01-11" version="1">MLSFILIQNRQGKTRLAKWYAPYSDDEKIKLKGEVHRLVAPRDQKYQSNFVEFRNNKIVYRRYAGLFFCACVDTNDNELAFLEAIHFFVEVLDAFFGNVCELDLVFNFYKVYAILDEVFLAGEIEETSKQVVLTRLEHLDKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QA64</accession>
    <name>E3QA64_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">NCS1 nucleoside transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_02896</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091772.1">
        <property type="nucleotide sequence ID" value="XM_008093581.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QA64"/>
    <dbReference type="STRING" id="645133.E3QA64"/>
    <dbReference type="GeneID" id="24408261"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02896"/>
    <dbReference type="eggNOG" id="ENOG502QQ8Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026016_2_0_1"/>
    <dbReference type="OrthoDB" id="2116389at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4160.10">
        <property type="entry name" value="Hydantoin permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026030">
        <property type="entry name" value="Pur-cyt_permease_Fcy2/21/22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31806">
        <property type="entry name" value="PURINE-CYTOSINE PERMEASE FCY2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31806:SF5">
        <property type="entry name" value="PURINE-CYTOSINE PERMEASE FCY21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002744">
        <property type="entry name" value="Pur-cyt_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="99"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="206"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="244"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="274"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="318"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="364"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="394"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="429"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="473"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR002744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ27752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="500" mass="54020" checksum="80FD7DD1797D5AB4" modified="2011-01-11" version="1">MESHPTTSKSHGGIDQSVAIEDGKIYHRESSRNPKWYQRLLDAGVEENGVLPVPLEKRTNTNYSNLFTVFFTSLLCLLPIPTGALATAQFGLSLRDASLVILFFSMLTTVAPAFMGIAGSYTGLRQLVQARYSFGYYLVSIPLLLNAATVTGFALSSSIVGGQTLAAVNPGHIDVKVGIVITCLVSFAASFVGYRALHMWERWQWLPNLVAMVIAVGCSGRHLWEQAEAPPPTAAQILNYGSIMAGYFITFGGTVSDFTVYHDPNNTTKLKMSSYIYLGILTPSIPLLVLGAAIGGALNNVPEWKSGWDTYGIGGVMAAMLVPAGVFGKVVLVVLALSVIGNVATSMYSVALCMQLMLPVFTKVPRIAFVVIALGIMIPMAIRAAEEWATSLQNFLGLIGYWAGFFDAVIIEELVLFRRMDYDSYDHAAWNAASVLPSGLAAIGASVLSFGLTIPGMDQVWFTGPVARTTGDIGFESAFVLTAIFYAPLRWLEIRKRGHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QB49</accession>
    <name>E3QB49_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Calcium influx-promoting protein ehs1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_03231</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ28087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092107.1">
        <property type="nucleotide sequence ID" value="XM_008093916.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QB49"/>
    <dbReference type="STRING" id="645133.E3QB49"/>
    <dbReference type="GeneID" id="24408596"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03231"/>
    <dbReference type="eggNOG" id="ENOG502QTA4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018731_0_0_1"/>
    <dbReference type="OrthoDB" id="5405745at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005262">
        <property type="term" value="F:calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098703">
        <property type="term" value="P:calcium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024338">
        <property type="entry name" value="MID1/Yam8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39142:SF1">
        <property type="entry name" value="AEL197CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39142">
        <property type="entry name" value="MID1P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12929">
        <property type="entry name" value="Mid1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ28087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="640" mass="69866" checksum="A617C41F089F3E60" modified="2011-01-11" version="1">MQLSPLQSRLAASLIASLLLILLYYLLSTPTFALAAELTGATQPLLDDLQHDDSLEPRSHLEPTYEPEFAAFDRSIVGRAPAGVTGLVNNVAINRNVPGNTTQNFVFEAIAIFADSLNEKDEALMLELREVVNDSSSPELASTEDVDLENEDRGLRRRQAQGRTVYISATTCIQPQRAGNNTKEDPQQIAMYVSTSQDNQTPGPGQNASLQTTIPFEEGAAMFRVNTTGDVFIGISAPAKDAEKFTGDWNFEVAVSTDDYFHSYDANPSELLWVDSDSSAALLTTQNLTDTQNETRIREIMEQGPPFVMFVENQDYPTTKGVRHSMCGLENYAQIAAMKGGKFGNLASTVMTTRGPGNLPKQQFFFNGLNASAFYTGILVETGNSSAMKKRQDGAGSTGGGGRVFEATPFETKDGDNCKIITDLQFCNETEYAVPANFNKMNIAQLAQFYDNYARDMYANFQKQLAQVACEAPAVQRYSLARNCADCEIAYKKWLCSVTIPRCEDFTNPTNFSLVRNTNQPFPNGTVLPADVQAMYNASVNQNSRNPLIDQMIAPGPYREILPCAYLCYDIAQSCPASLGFNCPTPDDAVFNSSYAIQVDGLLTCNYPGAVHRPSASSLLSVSWGLLSALIVGTLSAVML</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBH0</accession>
    <name>E3QBH0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_03453</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092329.1">
        <property type="nucleotide sequence ID" value="XM_008094138.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBH0"/>
    <dbReference type="STRING" id="645133.E3QBH0"/>
    <dbReference type="GeneID" id="24408818"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03453"/>
    <dbReference type="eggNOG" id="KOG1165">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019279_1_1_1"/>
    <dbReference type="OrthoDB" id="5800476at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14127">
        <property type="entry name" value="STKc_CK1_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000160">
        <property type="entry name" value="Casein kinase I 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000538">
        <property type="entry name" value="Putative Casein kinase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050235">
        <property type="entry name" value="CK1_Ser-Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11909">
        <property type="entry name" value="CASEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="13"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="318"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="398"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="414"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ28309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="452" mass="50469" checksum="C9F2B5A87C7EB5DF" modified="2011-01-11" version="1">MASSSSNVVGVHYRVGKKIGEGSFGVIFEGTNLLNNQQVAIKFEPRKSDAPQLRDEYRTYKILVGCPGIPNVYYFGQEGLHNILVIDLLGPSLEDLFDHCGRRFTIKTVVMVAKQMLSRVQTIHEKNLIYRDIKPDNFLIGRPGTKAANVIHVVDFGMAKQYRDPKTKQHIPYRERKSLSGTARYMSINTHLGREQSRRDDLEALGHVFMYFLRGGLPWQGLKAATNKQKYEKIGEKKQTTPIKDLCEGFPDEFNKYLTYVRNLGFEDTPDYDYLRELFTQALKNTGEVEDGEYDWMKITKDSGKGWDAMKGHNQGYLHNPNARPGPSQMELHSGHRGGAANPNNPQNLTVGRLNAAQPPPPSPIKQMAKSRGQPNAPGALSAQRGSGVGGLRDMATPTGSTQAQFQNSNRNLPQNVPQQAPMNQQQAQPNGRPAEPQPTGFQKFMKVLCCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBH9</accession>
    <name>E3QBH9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cwf18 pre-mRNA splicing factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_03462</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092338.1">
        <property type="nucleotide sequence ID" value="XM_008094147.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBH9"/>
    <dbReference type="STRING" id="645133.E3QBH9"/>
    <dbReference type="GeneID" id="24408827"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03462"/>
    <dbReference type="eggNOG" id="KOG3407">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091076_0_0_1"/>
    <dbReference type="OrthoDB" id="10261348at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005684">
        <property type="term" value="C:U2-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013169">
        <property type="entry name" value="mRNA_splic_Cwf18-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31551:SF1">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31551">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR CWF18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08315">
        <property type="entry name" value="cwf18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ28318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="208" mass="23114" checksum="B7E69F462E16F2FB" modified="2011-01-11" version="1">MSSSQGTLSAVTDERKARLAKLKNLKRKQPTDEVVPPESERAASPPAEPDVSRLHLSGRNYDPEARGPKLGFEAPPTQNLEQPTLEELAADIEADVRKKAAEESQDDKGIDLFKLQPKKPNWDLKRDLEKKLEILNVRTDNAIAKLVRERITGAQNAATQAKQVDSGSREGDAAGMDGIALVEGVRVREREEEEDERRQKEEDDDLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCI6</accession>
    <name>E3QCI6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">3-oxoacyl-[acyl-carrier-protein] synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_03718</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 11">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092594.1">
        <property type="nucleotide sequence ID" value="XM_008094403.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCI6"/>
    <dbReference type="STRING" id="645133.E3QCI6"/>
    <dbReference type="GeneID" id="24409083"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03718"/>
    <dbReference type="eggNOG" id="KOG1394">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_69_2_1"/>
    <dbReference type="OrthoDB" id="5334845at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000015">
        <property type="entry name" value="3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000024">
        <property type="entry name" value="3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017568">
        <property type="entry name" value="3-oxoacyl-ACP_synth-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03150">
        <property type="entry name" value="fabF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004970">
        <property type="entry name" value="PRK06333.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005589">
        <property type="entry name" value="PRK07314.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712:SF336">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="POLYKETIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000447">
        <property type="entry name" value="KAS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7 9" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="3 9" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="12">
        <location>
            <begin position="2"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="active site" description="For beta-ketoacyl synthase activity" evidence="10">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000447-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ28574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="430" mass="45644" checksum="E7D010E1F7FE38EB" modified="2011-01-11" version="1">MMRRVVVTGLGAISPFGVGVRSTWNRLLAGQSAITSVANLEPQTRWKDLKSTVAGVVPSHGSDPDHWRPDDWLDATEQRRMSRFAQYAVACAEMAMKDAGWQPSCQDDQEATGVCLGSGIGNLEEIYETSLAFNQQGYKKVSPLFVPKILVNLAAGHISIKYGLRGPNHAVTTACTTGAHSIGDAMRFIAFGDADVMVAGGTESCIHPLTFAGFGRARSLSTAYNHEPHASCRPFDRDRNGFVISEGSAVLVLEELEHAKARGARIYAEVRGYGCSGDAHHMTAPREDGHGAFRAMKLALKNAGVRPKEVSYINAHATGTQVGDAAEASAIRLIMTGEEGYADESCVTVSSTKGAVGHLLGAAGAIEAMFTVLSVAEDIVPPTLNLENPNVGGSMNLVPLQAQTKRVDNAISNSFGFGGTNASLVFSKLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCQ7</accession>
    <name>E3QCQ7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_03789</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0357 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092665.1">
        <property type="nucleotide sequence ID" value="XM_008094474.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCQ7"/>
    <dbReference type="GeneID" id="24409154"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03789"/>
    <dbReference type="eggNOG" id="ENOG502S73R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_128832_1_0_1"/>
    <dbReference type="OrthoDB" id="447314at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018559">
        <property type="entry name" value="DUF2015"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28023">
        <property type="entry name" value="UPF0357 PROTEIN YCL012C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28023:SF1">
        <property type="entry name" value="UPF0357 PROTEIN YCL012C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09435">
        <property type="entry name" value="DUF2015"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ28645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="128" mass="14390" checksum="B3EE2637613CE1D4" modified="2011-01-11" version="1">MPYLLYSVSFLLLVTATALYFTRSHWLPYLPDLPFPGRDYIYSRLPSSFAGDMDAGLSSSTFDLAANIESGDGRAGLDDRSKAEILKIMKKRRLKFDDARRAYMQQRFKANGIGPDGRPLDPKAVTFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QD55</accession>
    <name>E3QD55_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_03971</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092847.1">
        <property type="nucleotide sequence ID" value="XM_008094656.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QD55"/>
    <dbReference type="GeneID" id="24409336"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03971"/>
    <dbReference type="eggNOG" id="ENOG502T3ZS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099930_0_0_1"/>
    <dbReference type="OrthoDB" id="2873061at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35587:SF4">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35587">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="87"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ28827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="237" mass="26057" checksum="821C299F0CEB1F5A" modified="2011-01-11" version="1">MAPRNIMTSVPQPSRRRFAAPPSPGGQSDLIPDQDDILAELGLRVDDSASSMGGSTTGISMIDSGISVDGSGSGGGRRRRRRRNRNRNNQGSENNTININNNNSNNHGSNGNGNFNKQATLTIPRQGYSDRDERPVKLKLGLDLDVDLELKAKLKGDICISLVAERKTFSKRESMRVKPNWRGEVDVEEIFHMRIGRFRFRQRWIEREVSESLTAAVGFCIAVSGFVAGLAASRCLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDS2</accession>
    <name>E3QDS2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Telomere length regulation/capping, TEN1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_04154</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093030.1">
        <property type="nucleotide sequence ID" value="XM_008094839.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDS2"/>
    <dbReference type="GeneID" id="24409519"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04154"/>
    <dbReference type="eggNOG" id="ENOG502SESG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102601_1_0_1"/>
    <dbReference type="OrthoDB" id="5275361at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990879">
        <property type="term" value="C:CST complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043047">
        <property type="term" value="F:single-stranded telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016233">
        <property type="term" value="P:telomere capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024222">
        <property type="entry name" value="Ten1_fungal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12658">
        <property type="entry name" value="Ten1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ29010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="126" mass="13621" checksum="5BE7B0AA75BED332" modified="2011-01-11" version="1">MSRGPLPSQLCLLSDLPLRSPGEKVRFMGCVTSYSTHSAVLTLEHNFPKGSHVSALVDVQLLLGTIKSNETQIGEWVNVVGYVTPSPPGTRAKGTGEPRKAAIQALMLWSTGPIDLQRYESTFIIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEH0</accession>
    <name>E3QEH0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_04420</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093296.1">
        <property type="nucleotide sequence ID" value="XM_008095105.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEH0"/>
    <dbReference type="STRING" id="645133.E3QEH0"/>
    <dbReference type="GeneID" id="24409785"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04420"/>
    <dbReference type="eggNOG" id="KOG0605">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_396895_0_0_1"/>
    <dbReference type="OrthoDB" id="3638488at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050236">
        <property type="entry name" value="Ser_Thr_kinase_AGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356:SF400">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE CBK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="233"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="412"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ29276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="694" mass="80689" checksum="5D4CB76E3A65B38E" modified="2011-01-11" version="1">MHQATRGGNISRSNPTPVAPSITATHTLSPDLSPGFDGQALHSLWSPHVRSPAPKPNVLVKNKKHCQQESLGSNRDSSTTQKIIHRFRGMAKPASKLVHPRGLRHPVIQPVMNHPLGPPSPVISQDISPQRLPDKKKLEEQLVWGHISDKQRVLTVEKAAAAKIYLETYYKEVLRDDLTPRELRMARFRHDIHHLDQWEKEEYWKWYLKTETDHLRKQRVDKAYTRGSDLENLETLQILGKGSFGVVKLVWDRSHRHVYAMKVIRKSDMIRSCQEGHLRAERDFLAASENSQWIVSLIASFQDPTNLYLLMDYMPGGDFLGLLIRENILTESRTRFYIAEMILCVEEAHKLGCIHRDVKPDNFLIGADGHLKISDFGLAFDDHWSHDTSYYKWHRQWLLSLMGVRLDGDREDRKAARGGGYPQRPSSPAGSSKHAPPFNIVQSNALYSPPNYQTTLVFPVDGVQVSKMCQHLIRNLLQDKRDRLSSPKYRDQDERRARQQLLGHPETSRNYVFPNDANEIKAHPWFRGVPWEKMRFVQPEWIPNIKSFADAHYFKEDESISDWSESVDSDIGEGREDPADFDFRFLQVGFEHDVQALINDFTARPYDSTRLKRFDRDIENHSELEDIQKEYLKCYARRAGQKERKRPRDKLLRDPWVKDEVLQMRKQTSFLGYSWRCKSPLRRQGVHEHLPTFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEZ0</accession>
    <name>E3QEZ0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AT hook domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04355</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093231.1">
        <property type="nucleotide sequence ID" value="XM_008095040.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEZ0"/>
    <dbReference type="STRING" id="645133.E3QEZ0"/>
    <dbReference type="GeneID" id="24409720"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04355"/>
    <dbReference type="eggNOG" id="ENOG502QPW5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_585269_0_0_1"/>
    <dbReference type="OrthoDB" id="5243398at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017956">
        <property type="entry name" value="AT_hook_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00929">
        <property type="entry name" value="ATHOOK"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="435"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="467" mass="49992" checksum="615C09C3FC847ED8" modified="2011-01-11" version="1">MATTAASLQPLKHVASTSLEHSGTRTSTEIVTPIRSTSQTFASGSTKPKDEAHGFGILQHTGPPAKDDVLGLYRDGRVRNPVPSKLKGKTDARKGNFGVMHIDLSTTNETQERDAAAKRTSEGTQLAAKRAQTDRYVPFKRSKFIYRPEDQVASSPQQPDGAWQKTSPLTVAETKAEQARLLSLLQSLQPVLVVDQLCKALAFFGEVSNTQSPTNEAFPESAKANGPGSLFVGWLAEIFPALSQESIQSAQHPPSKRPRGRPKGSKNTKGKKDNVARKRFVPAGPLADPTGYSLVTSGLVRESVLDDSWVDMDDTTGTEGQILEGQLEQRSTTPSRNNQVMAGPNAADSVLGSASAKAAPVTSTPKRRGRPKGSKNRPKHKTILNNEIESAQDVSSAATGSAMLPNEVADDARSSVVPIPSSAPNDPVETGMVGVKKRKPGPGRPKGSKNRPKETYQSLPEKLLETI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFR3</accession>
    <name>E3QFR3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_04892</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">PP2A consists of a common heterodimeric core enzyme, composed of a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant regulatory subunit (PR65 or subunit A), that associates with a variety of regulatory subunits. Proteins that associate with the core dimer include three families of regulatory subunits B (the R2/B/PR55/B55, R3/B''/PR72/PR130/PR59 and R5/B'/B56 families), the 48 kDa variable regulatory subunit, viral proteins, and cell signaling molecules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the phosphatase 2A regulatory subunit B family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093768.1">
        <property type="nucleotide sequence ID" value="XM_008095577.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFR3"/>
    <dbReference type="STRING" id="645133.E3QFR3"/>
    <dbReference type="GeneID" id="24410257"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04892"/>
    <dbReference type="eggNOG" id="KOG2085">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012437_1_2_1"/>
    <dbReference type="OrthoDB" id="10264446at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005935">
        <property type="term" value="C:cellular bud neck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005816">
        <property type="term" value="C:spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070199">
        <property type="term" value="P:establishment of protein localization to chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008104">
        <property type="term" value="P:intracellular protein localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051754">
        <property type="term" value="P:meiotic sister chromatid cohesion, centromeric"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031578">
        <property type="term" value="P:mitotic spindle orientation checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000786">
        <property type="term" value="P:positive regulation of autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031107">
        <property type="term" value="P:septin ring disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031134">
        <property type="term" value="P:sister chromatid biorientation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000016">
        <property type="entry name" value="Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002554">
        <property type="entry name" value="PP2A_B56"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10257">
        <property type="entry name" value="SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10257:SF3">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT GAMMA ISOFORM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01603">
        <property type="entry name" value="B56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028043">
        <property type="entry name" value="PP2A_B56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="606"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="14"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="30"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="51"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="80"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="633"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="657"/>
            <end position="666"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00064351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR028043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ29748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="666" mass="75226" checksum="DE9B646ABEAC74C5" modified="2011-01-11" version="1">MKRFSQRVHAQLSRGKDPNKPKKNKDSKDGTASPSSVGSGRDANQSPNPTPSSSTTNLNDSRNKPLPPNNTGAHPGDHGSANQPSPLGNQQGAVPDRFNSAGAAQGANGGGSPARHGTLPPTVIISPSAPHVPPPGAAETMPHDLAPPKAGTKSLMFDRLHQTPKDVPEGLRTPKRQHSSRFDISAHRELEKLPGFHEVPPNRRQELFMQKIDQCNVIFDFNDASGDMKSKEIKRLALHELLDYVANNRQVITEPMYPRVVEMFAKNLFRPIPPPMNPQGEAFDPEEDEPVLEVAWPHIQVVYEFFLRFIESQDFNTNIAKAYIDHSFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLNLRSFIRRSINNVFFQFTYETERFNGIAELLEILGSIINGFALPLKEEHKTFLTRVLIPLHKVKSLSMYHPQLAYCIVQFLEKDASLTEEVVLGLLRYWPKVNSTKEVMFLNEVEDIFEVMDPAEFAKVQEPLFHQLAKSVASPHFQVAERALYFWNNEYFCNLVSDNVEIILPIMFAPLYENSKGHWNRTIHGMVYNAMKLFMEINPQLFDDCSHDYTEQQNSAAAREALRERKWASIADQAAQRRSANGVAGSGRAHAGSLSRVDEVDGTEDNQKRLDSLKLQDGDRRDRRHEQQDSVGSAHSQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFX5</accession>
    <name>E3QFX5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04954</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093830.1">
        <property type="nucleotide sequence ID" value="XM_008095639.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFX5"/>
    <dbReference type="STRING" id="645133.E3QFX5"/>
    <dbReference type="GeneID" id="24410319"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04954"/>
    <dbReference type="eggNOG" id="ENOG502SH9U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022730_0_1_1"/>
    <dbReference type="OrthoDB" id="429143at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847:SF260">
        <property type="entry name" value="FAD DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="1">
        <location>
            <begin position="41"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="473" mass="51791" checksum="05D52187C6BD9910" modified="2011-01-11" version="1">MARYPSCPLPAPQATESYWMSQADDRLKDYNSADRLPTDADTVIIGSGVTGVLIAQELLSRAAATDSRRHDGLVMLEARAFCSGASGRNGGHIKPDCYKHFLEFQARYGTDEAVRLCRFEVDNMRATVAFIRGQRLADVCDLVKTRAVDFFMTPEAWAAARESIAAYREAVGEELPDIHLHEQPDLSREGFRFPGALGAVSYPACSLWPYKLVAGLANRAVDAGMQLFTHTPALSVTPAAPAADGSPRWRVDTPRGTICCANVFHATNGYVSHLLPGFSAKIVPLKGNVVALPPPRPYVDRTLGHTASIQWGEDFDYMIQREVDGKHLIFGGRDLAHPRGCTAPIGDWDDSTTTPDIVRSLTEFPETHMMGWTGAGPPCYAWSGIMGLTPDELPYVGAVPDCAGQWVAAGYSGHGMARAFMTVQALIQLFARGDVDLRVPAEYFKIAERLVRKDDEWDQILERNLEANPPPVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGM0</accession>
    <name>E3QGM0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05152</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ30008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008095837.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGM0"/>
    <dbReference type="STRING" id="645133.E3QGM0"/>
    <dbReference type="GeneID" id="24410517"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05152"/>
    <dbReference type="eggNOG" id="ENOG502RPXA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028682_0_0_1"/>
    <dbReference type="OrthoDB" id="3903267at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
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        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="354"/>
            <end position="373"/>
        </location>
    </feature>
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        <location>
            <begin position="392"/>
            <end position="412"/>
        </location>
    </feature>
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            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
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            <begin position="31"/>
            <end position="42"/>
        </location>
    </feature>
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        </location>
    </feature>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="437" mass="48324" checksum="0A734102F5219EC4" modified="2011-01-11" version="1">MCDSSPSSCVDKASRWELSSSTSSPRSDSSTNPNHSLFSSPDSPAETEMSLPSLGPQDSQKSPINGQPQFVVMPSFANHIIGGQQAYTPGQIRAMRDTLLQARHTGEFPKTTSSSEDAQTIVEDYRLLKRLRDVRGDPMQPPPQAYNILKVDIARRIKARDEAQQGESNLEEIDHRVQGWMNSINKEARMLEITQAALQRKGINNPTQDDLDAIAEEFMQIAERTLLDVANPLRMNASRMEGNISRFDSQLSGMTSRINGLSSLDEAMTAQINTLNSVMTSQVNTLSTMLSSQSNTFNGSANMLNTALNTVSADLHQLTSNLPALIATAVQAAVREQLSSFSNQHDVNSQHRVNFEQPPGYTTVKRSQQNQQAGRETFTAFTYPVASKTQVSEQQHYEQTSHLSKPPKESKLNKLLRCIMGKGRSARKEDHERANSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
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    <organism evidence="3">
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        <name type="synonym">Glomerella graminicola</name>
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
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            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
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        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ30035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008095864.1"/>
    </dbReference>
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    <dbReference type="STRING" id="645133.E3QGP7"/>
    <dbReference type="GeneID" id="24410544"/>
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    <dbReference type="eggNOG" id="ENOG502R9U6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_148788_0_0_1"/>
    <dbReference type="OrthoDB" id="4525115at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
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            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="133" mass="14799" checksum="796656F60E9CFDF9" modified="2011-01-11" version="1">MAPATVWDDKARSDLLVAFLTVTKPSKEDWDRALAAVHEKGYTYTASAAIQHIQKLQRKEQTPGDSGEASATPTKKVAKKAATPRKRKTPVKKTKNESEAEDEEEQETPEQADDFLNVEDMAGDRFDHNDAEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGW6</accession>
    <name>E3QGW6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7918 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_05248</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EFQ30104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008095933.1"/>
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    <dbReference type="STRING" id="645133.E3QGW6"/>
    <dbReference type="GeneID" id="24410613"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05248"/>
    <dbReference type="eggNOG" id="ENOG502SAV6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070614_0_0_1"/>
    <dbReference type="OrthoDB" id="3364132at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057678">
        <property type="entry name" value="DUF7918"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36223">
        <property type="entry name" value="BETA-LACTAMASE-TYPE TRANSPEPTIDASE FOLD DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36223:SF1">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR EAF N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="9"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="281"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ30104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="344" mass="39102" checksum="F95956F0633A4000" modified="2011-01-11" version="1">MAIIRDFPGVKVTVQVDGRDATEYDDPDGFETDPNRKNARWRTFHYIESKDDAFFSVCYQVDNSHRWEGPDHALTLALYVDGKRASGMVCEAERFLNFDPLYVWETTVEGSRERSTTSGYDRLNKFKFSKVTTFDDAAIDRVKADTAKAKLLGVIEVFVYPVIITGPSTYTRSPHRHKARRSGNFEIAEKALKGRAVSHGTSFADGGIVSQRPSVTAEYLNNHNPIAAFSFKYRSRDALHKELIIPRSPSPEPIAGLSEAEIRRLAVERLDDINVSFPDSFTPQRNDDLMQNRRNSPTVKSESRRPIIKRECTEILDLTVEPAKREWKKIKIEGNRVAIDLTDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGY3</accession>
    <name>E3QGY3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Defect at low temperature protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">DLT1</name>
        <name evidence="9" type="ORF">GLRG_05265</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">Required for growth under high-pressure and low-temperature conditions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DLT1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ30121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094141.1">
        <property type="nucleotide sequence ID" value="XM_008095950.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGY3"/>
    <dbReference type="STRING" id="645133.E3QGY3"/>
    <dbReference type="GeneID" id="24410630"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05265"/>
    <dbReference type="eggNOG" id="ENOG502RAJJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022833_2_0_1"/>
    <dbReference type="OrthoDB" id="4096362at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038869">
        <property type="entry name" value="DLT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40021">
        <property type="entry name" value="DEFECT AT LOW TEMPERATURE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40021:SF1">
        <property type="entry name" value="DEFECT AT LOW TEMPERATURE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="302"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="400"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="308"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="325"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="402"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ30121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="444" mass="48654" checksum="3A226BAAE6D12F6E" modified="2011-01-11" version="1">MFSPRAIFRFIYGSFYFVLCFLLTLLLLITPGDTIYQAYSNNQPYNIWIIAATLVLTLLIVSFIYATRLYLNKTILASIPKSWVPIEKGDVNKKVHEMITADLKRSAAIAYDARPRIETSLLGSDMGDVLAEKQNSGGSAARKRFQLPTLKKPATTEKETGIALPPRRPVWGEIEHYGWASPNSIDLPDLQYSTVLSELPNLIEAKALTLAPPDPSSHAHPPMLDADAVALLQRPLPMSLRDYLSHLAELGVISLNATTADFLSTYEYARFSTRPISNAQFREVMHLFAAILRGMRPLDPAVLGPMDEPGEVSDSDIDNDAPMATNPTTPRSLSRSATQSTQGSYKRRGPALNARNSSANTWAQYRTAPATPLGTLAGAISRSSSLNSFAQTRQAYGPHQFSSNASLRSRASGSSTSGSVIRLATRTDSTDLPYILSLRETRTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QH79</accession>
    <name>E3QH79_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_05385</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697348">
        <property type="protein sequence ID" value="EFQ30241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094261.1">
        <property type="nucleotide sequence ID" value="XM_008096070.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QH79"/>
    <dbReference type="STRING" id="645133.E3QH79"/>
    <dbReference type="GeneID" id="24410750"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05385"/>
    <dbReference type="eggNOG" id="KOG0800">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076142_0_0_1"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15710">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE PRAJA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15710:SF243">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE PRAJA-2 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="129"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="187"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ30241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="201" mass="22353" checksum="D57FD5F3B9B22D0C" modified="2011-01-11" version="1">MATQYEIEHNIKSGPSTQEGTRRIDMSSFTSFLQNLTTNDAPSTTRHTNPHATPTPVDAAALYHLLQQQFQTLFSTAPNADNARFLSGLVEALERDIASPPTEIPGVSQEHLDSLDRVPKKALGKDEACPICAEKFLDDQYPLVVELPCHSSHRFDLECVSPWLRSKGSCPMCRKDLTKKKEQVVVPDDDEENDDPDGLYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QH96</accession>
    <name>E3QH96_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">SP-RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_05402</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein sumoylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NSE2 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697348">
        <property type="protein sequence ID" value="EFQ30258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094278.1">
        <property type="nucleotide sequence ID" value="XM_008096087.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QH96"/>
    <dbReference type="STRING" id="645133.E3QH96"/>
    <dbReference type="GeneID" id="24410767"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05402"/>
    <dbReference type="eggNOG" id="KOG2979">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028753_0_0_1"/>
    <dbReference type="OrthoDB" id="26899at2759"/>
    <dbReference type="UniPathway" id="UPA00886"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030915">
        <property type="term" value="C:Smc5-Smc6 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061665">
        <property type="term" value="F:SUMO ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16651">
        <property type="entry name" value="SPL-RING_NSE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026846">
        <property type="entry name" value="Nse2(Mms21)"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004181">
        <property type="entry name" value="Znf_MIZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21330">
        <property type="entry name" value="E3 SUMO-PROTEIN LIGASE NSE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21330:SF1">
        <property type="entry name" value="E3 SUMO-PROTEIN LIGASE NSE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11789">
        <property type="entry name" value="zf-Nse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51044">
        <property type="entry name" value="ZF_SP_RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SP-RING-type" evidence="12">
        <location>
            <begin position="289"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="164"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="266"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="372"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="183"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="380"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="394"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ30258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="417" mass="47739" checksum="D080CADA28DAB43D" modified="2011-01-11" version="1">MPILERRRPGQRRPERRVIDNDDEAPGSDLPEYEPLACPLTAEAKRAIAELSNSRDVHRYQNHVKASIRHLGTSVAGINDSVRIRHEHIQRLVEKRAESNDLGSQEKSQREVELETYTATLDDEVPRLTAEAEAALRDLIDRQVELDDEKAAMAETVSYFQAMPEQAPRQRRRTRVEAHGDDSNMDEEGDTVDDLPPPPDHSVIDILRQRRADKTHAYQRQPAYQRYALNNDYAAFKKLWHDAAHGDTEVPLPNAKRWFDNAGNPVMPATHRQPGNIKGEPGAQRADDSDEDIVIAGEVIDYRCPLSMQLFENPVSNNVCSHTYEKQWIVDMLQKAPTKRAQCPVAGCSMELGLDNLYDDQVILRKMKRALEEQRRREEEEADDSSSDDENEDEPRQVKREARGKSQKRKVEEIDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3QH98</accession>
    <name>E3QH98_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05404</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697348">
        <property type="protein sequence ID" value="EFQ30260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094280.1">
        <property type="nucleotide sequence ID" value="XM_008096089.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QH98"/>
    <dbReference type="GeneID" id="24410769"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05404"/>
    <dbReference type="HOGENOM" id="CLU_2263547_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="103" mass="11180" checksum="FA021B8E6A158B5A" modified="2011-01-11" version="1">MTDQLPVIKILQGDCEMKIVGKETKHTASDAKNRLESGETAASEGAFPHDAVAVTVNDMQVSVANVTFSMMGRATNYGDDVMAEEGEEETARASRYDVQPQEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QI14</accession>
    <name>E3QI14_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">1,3-beta-glucan synthase</fullName>
            <ecNumber evidence="3">2.4.1.34</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">1,3-beta-D-glucan-UDP glucosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_05646</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[(1-&gt;3)-beta-D-glucosyl](n) + UDP-alpha-D-glucose = [(1-&gt;3)-beta-D-glucosyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21476"/>
            <dbReference type="Rhea" id="RHEA-COMP:11146"/>
            <dbReference type="Rhea" id="RHEA-COMP:14303"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37671"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.4.1.34"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 48 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.34" evidence="3"/>
    <dbReference type="EMBL" id="GG697349">
        <property type="protein sequence ID" value="EFQ30502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094522.1">
        <property type="nucleotide sequence ID" value="XM_008096331.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QI14"/>
    <dbReference type="GeneID" id="24411011"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05646"/>
    <dbReference type="eggNOG" id="KOG0916">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000844_0_1_1"/>
    <dbReference type="OrthoDB" id="1880850at2759"/>
    <dbReference type="BRENDA" id="2.4.1.34">
        <property type="organism ID" value="1570"/>
    </dbReference>
    <dbReference type="PHI-base" id="PHI:9116"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000148">
        <property type="term" value="C:1,3-beta-D-glucan synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003843">
        <property type="term" value="F:1,3-beta-D-glucan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006075">
        <property type="term" value="P:(1-&gt;3)-beta-D-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051278">
        <property type="term" value="P:fungal-type cell wall polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026899">
        <property type="entry name" value="FKS1-like_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056261">
        <property type="entry name" value="FKS1-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003440">
        <property type="entry name" value="Glyco_trans_48_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12741:SF48">
        <property type="entry name" value="1,3-BETA-GLUCAN SYNTHASE COMPONENT FKS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12741">
        <property type="entry name" value="LYST-INTERACTING PROTEIN LIP5 DOPAMINE RESPONSIVE PROTEIN DRG-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14288">
        <property type="entry name" value="FKS1_dom1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23605">
        <property type="entry name" value="FKS1_dom2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02364">
        <property type="entry name" value="Glucan_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01205">
        <property type="entry name" value="FKS1_dom1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="507"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="547"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="585"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="611"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="672"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="724"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1348"/>
            <end position="1367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1400"/>
            <end position="1421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1517"/>
            <end position="1535"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1607"/>
            <end position="1628"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1652"/>
            <end position="1679"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1691"/>
            <end position="1716"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1722"/>
            <end position="1740"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1788"/>
            <end position="1811"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1848"/>
            <end position="1876"/>
        </location>
    </feature>
    <feature type="domain" description="1,3-beta-glucan synthase component FKS1-like" evidence="13">
        <location>
            <begin position="350"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="150"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="85"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="170"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ30502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1940" mass="221504" checksum="C045CF61160F2111" modified="2011-01-11" version="1">MSGYPAGGAGAGGHQDYDDGYGQHGRGQGNGTQQTDSYYQDDQQYYDQNGYDTHGQPPQGGDGYYDESGYYNADPNSAYHQDGGYYDNNEQYQDEYYNNGNNGNGYYDQDYNQGYAGAPRRQGSEEDSETFSDFTMRSDMARATDMDYYGRGDERYNSYDQGGARGFRPPSSQISYGGNRSSGASTPNYGMDYANMMSAASREPYPAWTSDAQIPLSKEEIEDIFLDLCAKFGFQRDSMRNMYDHFMILLDSRASRMTPNQALLSLHADYIGGDNANYRKWYFAAHLDLDDAVGFANMKGKGLRRKAKNKKKSKGEADNEADALEDLEGDNSLEAAEYRWKTRMNRMSQHDRVRQLALYLLCWGEANQVRFMPECLCFIFKCADDYLNSPACQNMVEPVEEFTFLNNVITPIYQFCRNQGYEISDGVYVRRERDHDKVIGYDDCNQLFWYPEGIEKIVLEDKSKLVDVPPAERYLKFKDINWKKCFFKTYKETRSWFHMLVNFNRIWIIHLTMFWFYTSANAPSVILGSKYEQQANNQPTKAQQFSIVGFGGTIAALIQVLATLAEWAYVPRKWAGAQHLTKRMLFLILILVINVAPFVYVFVLPNPNEKIAEILAIVEFVIALITFLFYSIMPLGGLFGSYLTKNSRKYVASQTFTASYPRLKGNDMAMSYGLWVAVFGAKFGESYVYLTLSFRDPIRYLSIMQIDCMGDKIIGNILCKNQHYVLLALMTFTDLIFFFLDTYLWYVLINALFSIARSFYIGSSIMTPWRNVFSRLPKRIYSKILATGDMEIKYKPKVLISQVWNAIVISMYREHLLAIDHVQKLLYHQVPSEQEGKRTLRAPTFFVSQEDHSFKTEFFPTNSEAERRLSFFAQSLSTPIPEPVPVDNMPTFTVLIPHYSEKILLSLREIIREDEPYSRVTLLEYLKQLHPHEWDCFVKDTKILADETSQFNGDSEKNEKDTVKSKIDDLPFYCIGFKSSAPEYTLRTRIWASLRFQTLYRTISGFMNYSRAIKLLYRVENPEVVQMFGGNSDKLERELERMARRKFKLCVSMQRYAKFKKEEMENAEFLLRAYPDLQIAYLDEEPPLAEGEEPRLYSALIDGHSEIMENGMRKPKFRIQLSGNPILGDGKSDNQNHSIIFYRGEYIQLIDANQDNYLEECLKIRSVLAEFEEMKTDNVSPYTPGVKNKMVNPVAILGAREYIFSENIGILGDVAAGKEQTFGTLFARTLSQIGGKLHYGHPDFLNGIFMTTRGGVSKAQKGLHLNEDIYAGMNALLRGGRIKHCEYYQCGKGRDLGFGSILNFTTKIGTGMGEQMLSREYYYLGTQLPLDRFLSFYYAHPGFHLNNMFIMLSVQMFMICLLSLGALRHETKACNYNRDVPITDPLFPTGCQNTDALMDWVYRCILSIIFVLLLAFVPLVVQELTERGIWRAAKRLGKQFGSLSPFFEVFVCQIYANSVQQDLSFGGARYIGTGRGFATARIPFGVLYSRFAGPSIYFGSRLLMMLLFATVTIWQGALVYFWISLLALVISPFLYNPHQFAWSDFFIDYRDYLRWLSRGNSRSHASSWIAFCRLSRTRITGYKRKALGDPSAKMSSDVPRAAITNMFWGEILTPLLLVATTVIPYLFINAQTGVEGANNSDISEPPKPTNSLIRVGVVALAPIAINAGLLMVMFFMACFMGPLLSMCCKKFGSVLAAIAHGVAVIMLLVFFEVMFLLESFEFARTLLGMIAVVAIQRFVFKLIISLTLTREIKTDAANIAFWTGKWYSMGWHSISQPAREFLCKITELSMFAADFILGHFLLFIMLPVILIPKIDMLHSMMLFWLRPGRQIRPPIYSMKQSKLRRKRVFRYAILYFLMFILFMALMIGPAVVGGMIPMDTFKMLNTADLALIQPTIYNNDNTHESSATGTGRPDYSGAYLTMTGSASASATSNSERVRLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIQ7</accession>
    <name>E3QIQ7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="7">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_05889</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the PPP phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="7"/>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094765.1">
        <property type="nucleotide sequence ID" value="XM_008096574.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIQ7"/>
    <dbReference type="STRING" id="645133.E3QIQ7"/>
    <dbReference type="GeneID" id="24411254"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05889"/>
    <dbReference type="eggNOG" id="KOG0371">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004962_8_1_1"/>
    <dbReference type="OrthoDB" id="1930084at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07415">
        <property type="entry name" value="MPP_PP2A_PP4_PP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000003">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047129">
        <property type="entry name" value="PPA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45619">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="8">
        <location>
            <begin position="133"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ30745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="328" mass="37371" checksum="6EABEB5959FFC946" modified="2011-01-11" version="1">MDTNMEDVGRVPADLPSAQNLEPTTIPTLDGWIESLMSCKQLVEADVQRLCEKAREVLQDESNVQPVKCPVTVCGDIHGQFHDLMELFKIGGPNPDTNYLFMGDYVDRGYYSVETVTLLVALKIRYPQRITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALIDNQIFCLHGGLSPSIDTLDNIRALDRIQEVPHEGPMCDLLWSDPDDRCGWGISPRGAGYTFGQDISEAFNHNNGLTLIARAHQLVMEGYNWSQDRNVVTIFSAPNYCYRCGNQAAIMEIDEHLKYTFLQFDPCPRAGEPMVSRRTPDYFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIU2</accession>
    <name>E3QIU2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nascent polypeptide-associated complex subunit alpha-like UBA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_05924</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094800.1">
        <property type="nucleotide sequence ID" value="XM_008096609.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIU2"/>
    <dbReference type="STRING" id="645133.E3QIU2"/>
    <dbReference type="GeneID" id="24411289"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05924"/>
    <dbReference type="eggNOG" id="ENOG502SUV6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_127753_1_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043066">
        <property type="term" value="P:negative regulation of apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050821">
        <property type="term" value="P:protein stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14361">
        <property type="entry name" value="UBA_HYPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052617">
        <property type="entry name" value="Huntingtin-int_K"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038922">
        <property type="entry name" value="HYPK_UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044034">
        <property type="entry name" value="NAC-like_UBA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31184:SF2">
        <property type="entry name" value="HUNTINGTIN-INTERACTING PROTEIN K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31184">
        <property type="entry name" value="HUNTINGTIN-INTERACTING PROTEIN K FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19026">
        <property type="entry name" value="UBA_HYPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nascent polypeptide-associated complex subunit alpha-like UBA" evidence="2">
        <location>
            <begin position="70"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ30780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="112" mass="11502" checksum="0FA9CD307B8E1A1E" modified="2011-01-11" version="1">MSEKQPPAGDVEEEVQPAKSAEDRKAASALASLDAGGDDSGNTQVDAEAAQKAIQGLGGATAAKKEVKNVKVDAADVALLVDELELPKPKATELLKANDGDAVKAMKAYLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIU4</accession>
    <name>E3QIU4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">amidase</fullName>
            <ecNumber evidence="3">3.5.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_05926</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a monocarboxylic acid amide + H2O = a monocarboxylate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:12020"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:35757"/>
            <dbReference type="ChEBI" id="CHEBI:83628"/>
            <dbReference type="EC" id="3.5.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amidase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.4" evidence="3"/>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094802.1">
        <property type="nucleotide sequence ID" value="XM_008096611.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIU4"/>
    <dbReference type="STRING" id="645133.E3QIU4"/>
    <dbReference type="GeneID" id="24411291"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05926"/>
    <dbReference type="eggNOG" id="KOG1212">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009600_9_3_1"/>
    <dbReference type="OrthoDB" id="6428749at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004040">
        <property type="term" value="F:amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1300.10:FF:000003">
        <property type="entry name" value="Amidase signature enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072:SF10">
        <property type="entry name" value="ACETAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072">
        <property type="entry name" value="AMIDASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001221">
        <property type="entry name" value="Amidase_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="7">
        <location>
            <begin position="64"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="5">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="208"/>
            <end position="211"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ30782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="561" mass="62937" checksum="AD7FB0BA47195459" modified="2011-01-11" version="1">MVYPFDYLQHRRDCQFKQSERADRIRRLTSYHGPFSAQDRQILDRPIEELVQDVHKTVLKPIDILKTYGKVAIKAHERTNCLTEVMIADAEKWVDDGSINMKGPLAGIPVSLKDTIVVGGYDTTVGFSSFVGNKTPDDGPVVRLLKDAGAVPYVKTNMPITLLSFESTNDVWGRCKNPHNTRYSPGGSTGGESALLAMGGRIGIGSDVAGSVRAPAHFSGCYSLRCSTGRWPKLGFCTSMPGQEGVPSVYSPMTRTLDDLRYFTRAVIGMQPWKYDYSVHPMPWRADAEKTWLEKPQFRVGVMRTDGVVDPSPACRRALEMVEAALRREGHEIVEIDPPSPYEGLQIASLALNADGCQTFSTFFRTGEWNDPGAAQMKFLMNLASPLRYLYYLWVKYVRRDEVWAGLVRDWRPQSAFENWKLVARREAYRARWFSWWDSAGVDVLITPPNATPAVPHDGMKDAVSSCGYTFLFNLLDYTAGVLPVTHVDENLDQLPGNFNITKLNGVARGAYKLYDAEDMHGLPVGVQVVGRRLEEEKVLSVMKRIEDALGEDKYELLEID</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIX2</accession>
    <name>E3QIX2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ANTH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_05954</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094830.1">
        <property type="nucleotide sequence ID" value="XM_008096639.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIX2"/>
    <dbReference type="STRING" id="645133.E3QIX2"/>
    <dbReference type="GeneID" id="24411319"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05954"/>
    <dbReference type="eggNOG" id="KOG0251">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014248_1_0_1"/>
    <dbReference type="OrthoDB" id="44015at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005905">
        <property type="term" value="C:clathrin-coated pit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030136">
        <property type="term" value="C:clathrin-coated vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005545">
        <property type="term" value="F:1-phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032050">
        <property type="term" value="F:clathrin heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005546">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048268">
        <property type="term" value="P:clathrin coat assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072583">
        <property type="term" value="P:clathrin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006900">
        <property type="term" value="P:vesicle budding from membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16988">
        <property type="entry name" value="ANTH_N_YAP180"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.150:FF:000004">
        <property type="entry name" value="ENTH domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.90:FF:000025">
        <property type="entry name" value="ENTH domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.150">
        <property type="entry name" value="ANTH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011417">
        <property type="entry name" value="ANTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014712">
        <property type="entry name" value="ANTH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045192">
        <property type="entry name" value="AP180-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013809">
        <property type="entry name" value="ENTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22951">
        <property type="entry name" value="CLATHRIN ASSEMBLY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22951:SF5">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN LAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07651">
        <property type="entry name" value="ANTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00273">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89009">
        <property type="entry name" value="GAT-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50942">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENTH" evidence="4">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="276"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="339"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="505"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="305"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="346"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="361"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="404"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="414"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="450"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="505"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="529"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="568"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="612"/>
            <end position="625"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ30810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="650" mass="71797" checksum="F95AD69205057D3D" modified="2011-01-11" version="1">MSSSFEKSVKGATKIKAAPPKTKYIEHILVATHAGEAGVAEVFRALQFRLRDSTWTVVFKSLITVHLMIREGSPDVTLSFLARHPNTLAISSFTDAQTQGRNIRHYANYLGARAKAYRETKCDWVRTKESRLEKLSVDKGLLRETEILQTQITALLKCDVLEGEIENEITVTVFRLLVLDLLALFQALNQGMINILGTFFEMSKVDAERAMSVYRNFTKQTDFVVQYLGVARQYEHQTRVEVPKLKHAPVNLGRQLEEYLQDPDFEINRRQYIAEQQAKKSGKGGISKPSSSAFDSKPAPAANNPFPSTNGSVQPKSETAKGPAPDLIDFFESIEQNQTTMASNTQQHQEQQQQQQQQQQMPMQTGFASNSPFQPQPTGFQQNGFAPQQTGFVPQQTGFGGNPYQPQSTNPFGQLQQLQQQQQQQQQQQQQAPQPLQPSFTGAGFGGFTPQPSFQPGTLGSIPQDSVASFPTGNTSMLSPQAGQQNTNPFRASMLMAQQTGMSTNIAFSNPMSPNTQRQSTNPFARSSPQAQQPFAPAPNDSPFQSQPQQQQQPLQLPPMAPLQPMMTGTNPFAKSLTASQLQQQRPATSSGALAPQPTGTTNPFRQGAFVNHQTGMGRQNNQQPIGGGLDNLETVPVFPRPMQQSPWQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJ88</accession>
    <name>E3QJ88_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_06070</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ30926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094946.1">
        <property type="nucleotide sequence ID" value="XM_008096755.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJ88"/>
    <dbReference type="STRING" id="645133.E3QJ88"/>
    <dbReference type="GeneID" id="24411435"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06070"/>
    <dbReference type="eggNOG" id="KOG0054">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_28_1_1"/>
    <dbReference type="OrthoDB" id="5241005at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042626">
        <property type="term" value="F:ATPase-coupled transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF399">
        <property type="entry name" value="ABC TRANSPORTER ATNG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="3">
        <location>
            <begin position="34"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ30926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="232" mass="25202" checksum="D12E94C1C5FF1648" modified="2011-01-11" version="1">METEESSQDVQLQSLKQSELVLGKKPRGGPAVIMNTVSLGWKSDSGPILESLDFEVQGGQLVMLVGPVASGKSTLLQGLLGELPHVTGTIELSSHRVSWCGQSPWLINETIRKNIICFSEFDAHLYRQVLTACDLEKDLAQLPEGDQTVIGSKGLALSGGQKQRVALARAIYSRPRIALFDNIFSGLDNKTTDAMFQRVFSAERGILRAWGTSIVLATQSGIAPNHEQEGQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJR6</accession>
    <name>E3QJR6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glucose/galactose transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_06248</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697353">
        <property type="protein sequence ID" value="EFQ31104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095124.1">
        <property type="nucleotide sequence ID" value="XM_008096933.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJR6"/>
    <dbReference type="STRING" id="645133.E3QJR6"/>
    <dbReference type="GeneID" id="24411613"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06248"/>
    <dbReference type="eggNOG" id="ENOG502QPVD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028452_3_1_1"/>
    <dbReference type="OrthoDB" id="546893at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050375">
        <property type="entry name" value="MFS_TsgA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43702">
        <property type="entry name" value="L-FUCOSE-PROTON SYMPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43702:SF3">
        <property type="entry name" value="PROTEIN TSGA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="105"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="249"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="311"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="344"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="369"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ31104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="438" mass="47796" checksum="166901CCD6151422" modified="2011-01-11" version="1">MGVKEFFHKRSLRHKDNVRTNAAELTLKESLFPIFLVTILFFLWGFSYGLLDTLNKHFQETLHITRARSSGLQAAYFGAYLIASLGHAAWILRHWGYKATFVFGLFLYGLGALIAIPCIIAKSFGGFCAAIFIIGNGLGSLETAANPYITVCGPPKYSEIRINISQAFNGIGTVVSPVMGSYVFFAFDDKRALENVQWVYLAIAVFVWSLAIVFWLARIPEITDADMAFQASETHANVDDKPFRKQYRLFHAAFAQFCYTGAQVAIAGFFINYVTERRPNTDSALGSKLLAGAQAAFAVGRFVGHGDIGMAMLYIVLFFESICFPTIVALGMRGLGRHSKRGSGVIIAGVSGGAVVPPLLGVVGDAKGMGTAMVIPLIFFVLALSYAFAVNFMPRYRNIADAFSATEVGIRPVDADWEKGGVESVEDKQTKKAVSTLS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2011-04-05" modified="2025-06-18" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKL1</accession>
    <name>MEP_COLGM</name>
    <protein>
        <recommendedName>
            <fullName>Extracellular metalloproteinase mep</fullName>
            <ecNumber>3.4.24.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName>Elastinolytic metalloproteinase mep</fullName>
        </alternativeName>
        <alternativeName>
            <fullName>Fungalysin mep</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="primary">mep</name>
        <name type="ORF">GLRG_06543</name>
    </gene>
    <organism>
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Secreted metalloproteinase that allows assimilation of proteinaceous substrates.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="induction">
        <text>Expression is controlled by the prtT transcription factor.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase M36 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-"/>
    <dbReference type="EMBL" id="GG697355">
        <property type="protein sequence ID" value="EFQ31399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095419.1">
        <property type="nucleotide sequence ID" value="XM_008097228.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKL1"/>
    <dbReference type="SMR" id="E3QKL1"/>
    <dbReference type="STRING" id="645133.E3QKL1"/>
    <dbReference type="MEROPS" id="M36.001"/>
    <dbReference type="GlyCosmos" id="E3QKL1">
        <property type="glycosylation" value="2 sites, No reported glycans"/>
    </dbReference>
    <dbReference type="EnsemblFungi" id="EFQ31399">
        <property type="protein sequence ID" value="EFQ31399"/>
        <property type="gene ID" value="GLRG_06543"/>
    </dbReference>
    <dbReference type="GeneID" id="24411908"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06543"/>
    <dbReference type="eggNOG" id="ENOG502QTDC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012703_3_0_1"/>
    <dbReference type="OrthoDB" id="3227768at2759"/>
    <dbReference type="PHI-base" id="PHI:12176"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09596">
        <property type="entry name" value="M36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011096">
        <property type="entry name" value="FTP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050371">
        <property type="entry name" value="Fungal_virulence_M36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001842">
        <property type="entry name" value="Peptidase_M36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33478">
        <property type="entry name" value="EXTRACELLULAR METALLOPROTEINASE MEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33478:SF1">
        <property type="entry name" value="EXTRACELLULAR METALLOPROTEINASE MEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07504">
        <property type="entry name" value="FTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02128">
        <property type="entry name" value="Peptidase_M36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00999">
        <property type="entry name" value="FUNGALYSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00142">
        <property type="entry name" value="ZINC_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-0325">Glycoprotein</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0482">Metalloprotease</keyword>
    <keyword id="KW-0645">Protease</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0964">Secreted</keyword>
    <keyword id="KW-0732">Signal</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <keyword id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="propeptide" id="PRO_0000407181" evidence="1">
        <location>
            <begin position="23"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_0000407182" description="Extracellular metalloproteinase mep">
        <location>
            <begin position="249"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="434"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="433"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="437"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="2">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="2">
        <location>
            <position position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="4"/>
    <sequence length="639" mass="69318" checksum="405CE23844D50056" modified="2011-01-11" version="1" precursor="true">MYRSMKSLALLGLLGPTSQVFAHPATGHAHNIGRRGVDIEAFRLPQVGSYTNATEIETTPPIALLKRESYVETATELVKKLAPNSEFRLVGDHYVGTNGIGHVNFKQTVHGLDIDNGDFNVNIGKDGKVFSYGNNFFKGEAPEASPLKKRDFKDPVSALKGAKDVLQLPVEAASASAEPKEGTEVYSIKGTSGTVSDPEARLVYFVKADGSLALSWRVETDITENWLLTYVDAETGTDVHGVVDYVSDLANYRVYPWGVNDPTEGDRVLVTDPWDISASPLTWQSDGTTNYTTTRGNNGIAQSNPSGGTAYLNNYRPTSAARNFDYQYTTSLTTPSSYIDASIAQLYYTANHYHDLLYTLGFTESAGNFQINNNGKGGVGNDFVVLFAQDGSGTNNANFLTPPDGSNGRMRMYLWTMSTPRRDCSFEAGVVIHEYTHGLSTRLTGGPANSNCLNALESGGMGEGWGDFFATAIRLKPTDTRATDYSMGAWVYNNPAGIRSVLYSTSMTTTPNTYSTINGVSSVHRIGETWATTLYEVLWNLIDKHGKNDGPRPEFDSNGVPTDGKYLTLKLVLDGMALQPCSPNFIQARDAILDADKALTGGDNLCELWTAFAKRGLGSNAVYSSSNRRDGFNVPAGVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QL22</accession>
    <name>E3QL22_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">D-serine dehydratase</fullName>
            <ecNumber evidence="11">4.3.1.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">D-serine deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">GLRG_06849</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the conversion of D-serine to pyruvate and ammonia. May play a role in D-serine detoxification.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-serine = pyruvate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13977"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:35247"/>
            <dbReference type="EC" id="4.3.1.18"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:13978"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DSD1 family.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.18" evidence="11"/>
    <dbReference type="EMBL" id="GG697356">
        <property type="protein sequence ID" value="EFQ31560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095580.1">
        <property type="nucleotide sequence ID" value="XM_008097389.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QL22"/>
    <dbReference type="STRING" id="645133.E3QL22"/>
    <dbReference type="GeneID" id="24412214"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06849"/>
    <dbReference type="eggNOG" id="ENOG502QRZ0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031639_0_0_1"/>
    <dbReference type="OrthoDB" id="20198at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008721">
        <property type="term" value="F:D-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036088">
        <property type="term" value="P:D-serine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009636">
        <property type="term" value="P:response to toxic substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.10:FF:000016">
        <property type="entry name" value="D-serine dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="entry name" value="Alanine racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.20">
        <property type="entry name" value="D-serine dehydratase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051466">
        <property type="entry name" value="D-amino_acid_metab_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026956">
        <property type="entry name" value="D-ser_dehydrat-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042208">
        <property type="entry name" value="D-ser_dehydrat-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28004:SF2">
        <property type="entry name" value="D-SERINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28004">
        <property type="entry name" value="ZGC:162816-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14031">
        <property type="entry name" value="D-ser_dehydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01119">
        <property type="entry name" value="D-ser_dehydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="PLP-binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0216">Detoxification</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="D-serine dehydratase-like" evidence="14">
        <location>
            <begin position="280"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00051198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00055764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00066349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00069616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00075219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EFQ31560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="401" mass="43474" checksum="E060F6579E95FB46" modified="2011-01-11" version="1">MDYSLQNHKSLIGSKALDLPSPSLVLSLPVIKKNIEKLHQDVEKAGVTLRPHVKTLKSLEVTRLMLGNGKFKKTVASTLSEIRGLLPLAEDGTLDEVLYGLPPALGAIPFLSDLRKSVKILLMIDHEKQISLLEDFAKKNPETSGGAWDIYIKLDVGTKRAGLPLGGERLQKLIQRADGSSAVSLYGFYCHAGHSYASRTQEEAESFLADEINGVLSAAKLIVGDRKLTLSVGATPTAHVVGSLKTTIPDNVTLELHAGNFPTNDLQQVATGLVGPEDQAVRVVAEVCSVYPERNEALINAGTIALSKETGPFPGFGSVVGKPGWAVVRMSQEHGIVGEVNSPGSKNTEPEKRDVEENFEIGDKVFINIQHACITAASFYVYYVVDDNDVVRDTWVPWKGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QL35</accession>
    <name>E3QL35_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_06862</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697356">
        <property type="protein sequence ID" value="EFQ31573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095593.1">
        <property type="nucleotide sequence ID" value="XM_008097402.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QL35"/>
    <dbReference type="STRING" id="645133.E3QL35"/>
    <dbReference type="GeneID" id="24412227"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06862"/>
    <dbReference type="eggNOG" id="KOG0730">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025506_1_0_1"/>
    <dbReference type="OrthoDB" id="2115716at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990275">
        <property type="term" value="F:preribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19481">
        <property type="entry name" value="RecA-like_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF132">
        <property type="entry name" value="ATP-DEPENDENT ZN PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase AAA-type core" evidence="2">
        <location>
            <begin position="274"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ31573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="509" mass="58443" checksum="4FB445CC9B62216D" modified="2011-01-11" version="1">MPPLPMPPHDIWNPDGFQSPELAIAVERLSRRTNPHTSSNPPRTTTRDSEPGNGDSVTKEYFKHSSAKRVNTDALVFKALKEQYPHLELVVVPEAVGFNDCNLLGFARAGHASCELIEDKGTNLPSSIEWLIYLAPARRLDGEQGGLASTTKFGKYLYKWQGHEFIVYLIDGRDGTVPYPVKNYYILAPETYHIDQLVLAAGKWSSDLHDEVWVFDEGYWQKSRELFESFRNASWDSVILDQDMKKAVIDDHLSFFNSRDTYQNLKVPWKRGLIYYGPPGNGKTISIKATMNMLHQMNIPTLYVRTLVSYMGPEYSIKQVFGKAREYAPCYLVFEDLDTIVSENVRSYFLNEMDGLKSNDGIFIIGSTNHLDRLDPGISKRPSRFDRKYLFPDPNLEQRIAYCRFWQKKLRANEEIVFPDKLCEAIAKITDKFSFAYIQEAFVAALLAIARRSHQQGRRDSVQALTEQLEDDWLGVVDASEDEDLKKLVLWVEIKKQIEILRDGMEEEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLS4</accession>
    <name>E3QLS4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metallopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_06787</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697357">
        <property type="protein sequence ID" value="EFQ31812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095832.1">
        <property type="nucleotide sequence ID" value="XM_008097641.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLS4"/>
    <dbReference type="GeneID" id="24412152"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06787"/>
    <dbReference type="eggNOG" id="KOG4525">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009601_2_1_1"/>
    <dbReference type="OrthoDB" id="74460at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09613">
        <property type="entry name" value="Jacalin_metallopeptidase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.100.10.30">
        <property type="entry name" value="Jacalin-like lectin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001229">
        <property type="entry name" value="Jacalin-like_lectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036404">
        <property type="entry name" value="Jacalin-like_lectin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033862">
        <property type="entry name" value="Jacalin-like_metallopeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053002">
        <property type="entry name" value="Metalloproteinase_M10B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021917">
        <property type="entry name" value="Unchr_Zn-peptidase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21054:SF2">
        <property type="entry name" value="MIP04191P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21054">
        <property type="entry name" value="ZINC METALLOPROTEINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01419">
        <property type="entry name" value="Jacalin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12044">
        <property type="entry name" value="Metallopep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51101">
        <property type="entry name" value="Mannose-binding lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51752">
        <property type="entry name" value="JACALIN_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Jacalin-type lectin" evidence="2">
        <location>
            <begin position="625"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ31812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="763" mass="83990" checksum="E806C5E57F4ABA08" modified="2011-01-11" version="1">MAPSILNFRALRRRSKASFKTDRSNTDVSSDASNATTPTPTSGASTPPSIAQASDPAFDLHLKDSNHPQARPPLQPVPNSHRQSVPGMTGLGSPVVNGKWTLPTSPYAPRIANVTENAWVYQKVLLVHGTIGDPSQHALDGNLSVTRLDDGFPPTSWPVSDSHFKALVYLQPGPNKIRFDFSSPKLPNSSSSNPIHASYLTVHMLPINNAPPLQLAIVVAKDSPETFDAVPARVEREGNGLETAVRKFRMAAYLWQAFTAEQMWRNKLGRRVFRFEEEWVVGTSNLRDRENGTLRSEARIHIIRSDKTVAEIRDLELAQQNEKSSKKGDLFGIAAEAVKQYFKPLGDQKQYVSVLMLDTQWDKEANVIRGHAALGGNAGELQLAIFGSHCLQSYPTSFEEVVPAFTDCTPTDLDFVANDCNQAGSSWEAANIGIGAHLHETGHLFGCPHQETGVMLRDYLTLNRSFVTREAYCSRTNSKGGLVLQADECGWHRLDCLRFRTHPCFRLPNDPPMNADDSVHAFPVEGGNIVVMAATGIAFIELFAEDDDVCRKWIEYPIENGSVQRQLTLNDRELRERLPENKRKGQLRVSIKSHGCGALDIEDFKKLCSKESSFKLTPGPLGKTAYRGKALGTSAMEGTVAQEVVFDSAVKSNLVLSRVIFYHGYAVDGIEFVYDDDSTQLFGKRGGKEDIRRGEYISGFYVRSGFWIDAIQVLTSLGRRSPVYGNAHGGSAHTLIPPRGYTICGVAGSCGAWVDGFSILIVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLU8</accession>
    <name>E3QLU8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Abhydrolase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_06980</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095856.1">
        <property type="nucleotide sequence ID" value="XM_008097665.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLU8"/>
    <dbReference type="STRING" id="645133.E3QLU8"/>
    <dbReference type="GeneID" id="24412345"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06980"/>
    <dbReference type="eggNOG" id="KOG1552">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029375_3_0_1"/>
    <dbReference type="OrthoDB" id="446723at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277">
        <property type="entry name" value="ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277:SF81">
        <property type="entry name" value="PROTEIN ABHD13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="142"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ31836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="402" mass="44770" checksum="B06D60B1E55D27E4" modified="2011-01-11" version="1">MTVPLSPMLRTAVWVVVAPLGLYFTFLALGASPFFQRHFLYAHKINTLWWRDVNEPERWGFAKGQVTPFSLETPDGVSLYAWHVMPLPEYLKQEERFSAQRSGFCHDFTQTESFKALKENPDARVVLYFHGNAGDIAQNHRPGSYHVITDTSSYHVLAIDYRGFGHSTGTPSEHGLIQDAATLIDWVINTAGVPSERIVLLGQSLGTAVTSGVAELYASQGIDFGGIVLVAGFSNLPKMLRGYRIGGIFPVLGPLKVWPGFLEYMESFIYEKWPSVDRLESLVKLSKRRLRLTLISALDDADIPWTESSKLFRSAANATVPGGLDDHSFEAWKEVRTIRKGKDAFVTTWTAEPNMIIRQELFPHGGHNDIMGYAPVILAIMRSFDFGGTAYDTASSDTGRTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLW2</accession>
    <name>E3QLW2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">chitinase</fullName>
            <ecNumber evidence="4">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">GLRG_06994</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="4"/>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095870.1">
        <property type="nucleotide sequence ID" value="XM_008097679.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLW2"/>
    <dbReference type="STRING" id="645133.E3QLW2"/>
    <dbReference type="GeneID" id="24412359"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06994"/>
    <dbReference type="eggNOG" id="KOG2806">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002833_2_4_1"/>
    <dbReference type="OrthoDB" id="73875at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00035">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.10">
        <property type="entry name" value="Endochitinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001002">
        <property type="entry name" value="Chitin-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036861">
        <property type="entry name" value="Endochitinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF333">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00187">
        <property type="entry name" value="Chitin_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00270">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57016">
        <property type="entry name" value="Plant lectins/antimicrobial peptides"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50941">
        <property type="entry name" value="CHIT_BIND_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="6 12" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10 13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 13 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179854" description="chitinase" evidence="14">
        <location>
            <begin position="26"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="15">
        <location>
            <begin position="67"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="16">
        <location>
            <begin position="123"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="85"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="90"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EFQ31850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="482" mass="52971" checksum="0ACF8EB95CB62270" modified="2011-01-11" version="1">MAKYRALFPYFSLVFILSLIAPIHAQDIPICSASVPCEDGCCNKSGLCGLGPDYCSKSTCVNNCDRKAQCDPGGFGEDYVVKTTCPLNVCCSEYGYCGTTETSCGNNRANRPSCPVEENSSFKRVVGYYETWATGRACNRFFPEQIPAGVYSHINIAFISINPSTFELVPAEKGDVDLYKRVANLKAEDPHLKVLIAVGGTDFHNTGPTAATFSDIARSQEAQKKFTDSVLNFMSTYGLDGIDLDWEYPGVEDRGGRVEDFANLPKFVKTLRQGLKDYEISVTIPAIYLNLQHFDLKNIEPHVDFFNVMAYDFHGVWNKPTELGGPYFSSHTNLTEIKDGLDLLWRNNVNHDKVVLGLAFYGRGFQASDSSCLRPGCTFESGSDAQPCSGEDGAALNSEIDDLVAKQGTKSTLDTDAAVKVLTWGGDNWLTYDDEETFRLKADFARSQCLGGVMVWAISQDTENAKYSKALSRVAPRISGSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QM33</accession>
    <name>E3QM33_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tri14-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07065</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095941.1">
        <property type="nucleotide sequence ID" value="XM_008097750.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QM33"/>
    <dbReference type="STRING" id="645133.E3QM33"/>
    <dbReference type="GeneID" id="24412430"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07065"/>
    <dbReference type="eggNOG" id="ENOG502SEA5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052674_0_0_1"/>
    <dbReference type="OrthoDB" id="4434395at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12811">
        <property type="entry name" value="MALA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054550">
        <property type="entry name" value="Mala_s_1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22701">
        <property type="entry name" value="Mala_s_1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101898">
        <property type="entry name" value="NHL repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180698" description="Tri14-like protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="352" mass="37960" checksum="D77A07D0129C7C06" modified="2011-01-11" version="1">MDIHTLLVNILVVVLGTLSPVESTPQLERRCLPFANGSFVIHQHQLYPDCADWDVDNCVLYFGSKANASVVVYDPYMNKIVDVLMLSDITQNPNLQIGGVRVDQHTNLVSIVTNAAAPFNAAGQNVSGDSFITKYDVAKKQVLWSKNITDVSKGEYAGFRDIGYDPLGNTYVVGTFPGTIMKVNQEGSDIIPWYLPAKIDNTKTGFSGLAAVGNILITSNNEDSQIYRFDMTAEKGTPVLVRRSPDATLAMTGVIYLPQKYDGKVLLVAENAKGITVLRSSDGSWQSAEHLGTVPNNSLAAPGGTITAAVQVGDSLYMVEGFSTDPSVSNSTAGNRTEFPMVDITLEVEGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMA9</accession>
    <name>E3QMA9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07141</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096017.1">
        <property type="nucleotide sequence ID" value="XM_008097826.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMA9"/>
    <dbReference type="GeneID" id="24412506"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07141"/>
    <dbReference type="eggNOG" id="ENOG502T6JJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_144284_0_0_1"/>
    <dbReference type="OrthoDB" id="4819332at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="117" mass="12949" checksum="201055ADA0828760" modified="2011-01-11" version="1">MSESPTTSARNQRDPGSPTITGIPSILTVLREPESFSNDDDRRAQQYRHQSPETASKLARETLISMCKTIGVVGAQLNSSTNDSDFQLRQLIHLARNISKRLDNHDSNGYAGPPRVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMP1</accession>
    <name>E3QMP1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">GPR1/FUN34/YaaH-class plasma membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_07273</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096149.1">
        <property type="nucleotide sequence ID" value="XM_008097958.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMP1"/>
    <dbReference type="STRING" id="645133.E3QMP1"/>
    <dbReference type="GeneID" id="24412638"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07273"/>
    <dbReference type="eggNOG" id="ENOG502S179">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051062_4_0_1"/>
    <dbReference type="OrthoDB" id="3648309at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015123">
        <property type="term" value="F:acetate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051633">
        <property type="entry name" value="AceTr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000791">
        <property type="entry name" value="Gpr1/Fun34/SatP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123:SF4">
        <property type="entry name" value="PROTEIN ALCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01184">
        <property type="entry name" value="Gpr1_Fun34_YaaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="156"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="226"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ32129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="314" mass="34044" checksum="1BDBAAED5E9A4E0D" modified="2011-01-11" version="1">MSTMDHKEELKELRSDSYHREHRHPEHQSNQPHRVPNGYDDPDADYIAPHASRDDALNRMKTAGSVNMSPELFEKLYLSPQNKVKGDLRKTFGNPTPIAIVGFLLSLTPLACDLMGWRGAGGSGAAGIGSYFFFGGLLMFVGGLLEWILGNTFPSVVFFTFSAFWFTFGATLNPSFAAFSSYAPAGAASGAAGLTTQGFNASFGFITLAMAMICVVFLVCSLRTNVVFFIIFLTLVAAFCLITAAYWFLAMDYTGNAAYAAKLLKGAGGCAFATCMAGWWLIFAILLASLDFPLELPVGDLSRVIRGKSEKSHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMP7</accession>
    <name>E3QMP7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">T-complex protein 1 subunit alpha</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">CCT-alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_07279</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096155.1">
        <property type="nucleotide sequence ID" value="XM_008097964.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMP7"/>
    <dbReference type="STRING" id="645133.E3QMP7"/>
    <dbReference type="GeneID" id="24412644"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07279"/>
    <dbReference type="eggNOG" id="KOG0360">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008891_5_1_1"/>
    <dbReference type="OrthoDB" id="10248520at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd03335">
        <property type="entry name" value="TCP1_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000009">
        <property type="entry name" value="T-complex protein 1 subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012715">
        <property type="entry name" value="Chap_CCT_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053374">
        <property type="entry name" value="TCP-1_chaperonin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054827">
        <property type="entry name" value="thermosome_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02340">
        <property type="entry name" value="chap_CCT_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041082">
        <property type="entry name" value="thermosome_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041083">
        <property type="entry name" value="thermosome_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ32135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="566" mass="61648" checksum="4315D7C39BDB5750" modified="2011-01-11" version="1">MASMFEQSGSGTLFLGGQKISGADIRDQNVLATQAIANVVKSSFGPSGLDKMMVDDIGDVTVTNDGATILSLLDVEHPAGKILVDLAQQQDKEVGDGTTSVVLIAAELLRRGNELMRNRIHPTTIITGYRLALREAVKYMNENISIKVENLGRESLVNIAKTSMSSKIIGADSDFFANMVVDAMLAVKSTNNRNETKYPVKAVNILKAHGKGSLESLLIKGYALNCTVASQAMPTRIQDAKIAVLDMNLQKERMKLGVQITVDDPQQLEQIRQRESGMILERVEMILKAGANVILTTKGIDDMVLKTFVEKGAMGVRRCKREDLRRIAKATGATMLSTLSDLNGDEKFDPSYLGHAEEVVQERISDDECILVKGTKSHSSASIILRGPNDFTLDEMERSIHDSLNAVKRTLESGSIVPGGGSVETALHIYLEEFAGTVGSREQLAIGEFAQSLLVIPKTLAVNAAKDASELVAQLRSRHALSQRIQEGEANEDEKTVARKKAYKNYGLDLVRGKVIDEIKAGVLEPTISKIRQLKSAVEACISIMRIDTLIKLDPEQRAEDDGHGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMS3</accession>
    <name>E3QMS3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Actin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_07305</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the actin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697360">
        <property type="protein sequence ID" value="EFQ32161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096181.1">
        <property type="nucleotide sequence ID" value="XM_008097990.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMS3"/>
    <dbReference type="STRING" id="645133.E3QMS3"/>
    <dbReference type="GeneID" id="24412670"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07305"/>
    <dbReference type="eggNOG" id="KOG0676">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023246_0_0_1"/>
    <dbReference type="OrthoDB" id="337660at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="294"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="431"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="535"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="32"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="437"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="457"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ32161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="579" mass="63580" checksum="4D9CACA5BA64C997" modified="2011-01-11" version="1">MSSSAAPSIPHRSIANIRTETGPSIGGPASPHTPSRTISSTFGSPSSLRAEDDNIVIELGSRFIKLGFAGESSPKAVLSFGPEKLRRVGDFRTWDPEHKNDWRRRPTGKTWGVEHELWQFDVRTVDLGLVEDKIDRAIREALNKFLLIDSRPRRTSLVLSSSTPLPLLSTALDVLFHRFQAPTVSLMSSAVMSTVGAGTRSAVVVDLGWAETAVTSVYEYREARTSRTVRGGKMLVSETHNLLQDALSATPVHAQRTLRERDQGQHSLSFEECEEVACRLVWCRQLAQSELPGLGKRQQTTPGDVLPTVEEQDESAPPSPVARDESKGNIDILLQSVEPPENLTLSLQQLSEPCENTYFAPKYSRSSFDDDELPVHHLLYQHLVQLPIDTRAICMSRIIFIGGCSRVVGLRRRIFDELSKLVHERGWNPVQGRAPQQYKSNTMLKRTNSGPASDGPTEEKPVAKGTVERNVADDEAFYAADAIGESLRKRERHHAKVQGVLRSLGSLGPWGGASLACQLKVAAMANIDRDTWLQQGANGASRPSEVDVKSQQRQSMGPGGLMRGASGQAAWTLGAWGAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNQ9</accession>
    <name>E3QNQ9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07686</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697362">
        <property type="protein sequence ID" value="EFQ32416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096436.1">
        <property type="nucleotide sequence ID" value="XM_008098245.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNQ9"/>
    <dbReference type="STRING" id="645133.E3QNQ9"/>
    <dbReference type="GeneID" id="24413051"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07686"/>
    <dbReference type="eggNOG" id="ENOG502RR34">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073919_0_0_1"/>
    <dbReference type="OrthoDB" id="512662at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052523">
        <property type="entry name" value="Trichothecene_AcTrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791:SF4">
        <property type="entry name" value="ACETYLTRANSFERASE, GNAT FAMILY FAMILY (AFU_ORTHOLOGUE AFUA_4G09540)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791">
        <property type="entry name" value="GNAT FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="59"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="231" mass="26019" checksum="31B74741FE713E09" modified="2011-01-11" version="1">MLIRVTDLTEADIPGAVKAVQQAFSGDPYNAWVYDQSKFSPERNYASLALRMRWGMRNGIFHVAKEEGSDAVLGVAMWLLPKPAGAPPTWTDWLEGWRLWLGQLNYNLWYGRGGLNVKRYYIWKDAQAKAQRDLWTDPRGYYFLNIMVVLPEAQGKGVGTAMMRAVTRRADAEGVKCYLESSRDVPNTAIYGRWGFVVQRDMVCDDAGDAIRLFSMIREPGAAPGDGRGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNY8</accession>
    <name>E3QNY8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DJ-1/PfpI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_07590</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697363">
        <property type="protein sequence ID" value="EFQ32576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096596.1">
        <property type="nucleotide sequence ID" value="XM_008098405.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNY8"/>
    <dbReference type="STRING" id="645133.E3QNY8"/>
    <dbReference type="GeneID" id="24412955"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07590"/>
    <dbReference type="eggNOG" id="ENOG502SMQ8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_44_8_1"/>
    <dbReference type="OrthoDB" id="543156at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052158">
        <property type="entry name" value="INH-QAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130">
        <property type="entry name" value="ARAC-FAMILY TRANSCRIPTIONAL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130:SF7">
        <property type="entry name" value="DJ-1_PFPI DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ32576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="233" mass="25967" checksum="7D7C35D60E2E580E" modified="2011-01-11" version="1">MSFNLSEPGRAIRAGVILTKGVTEMLDVAPFEFFAWTDKAMCQMLNLPREMWKDTFAVELHWITEDGKPARMRSAAVIQPTDSFESCPPLDIALMGAHDADYKTSEAELAFIRKVWGECSAFLTICGGMIPPLEAGILTGKTATCPRPMIGVMKKKVPVVNWVETRWARDGKLWTSSTLLNGTDMVRAFAESTWGGKNGMVEAMLDTAAFPTRDVDFKDFKGHHYTVEEVDFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPD1</accession>
    <name>E3QPD1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Palmitoyltransferase</fullName>
            <ecNumber evidence="11">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_07863</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="11"/>
    <dbReference type="EMBL" id="GG697364">
        <property type="protein sequence ID" value="EFQ32719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096739.1">
        <property type="nucleotide sequence ID" value="XM_008098548.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPD1"/>
    <dbReference type="STRING" id="645133.E3QPD1"/>
    <dbReference type="GeneID" id="24413228"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07863"/>
    <dbReference type="eggNOG" id="KOG1311">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021757_0_0_1"/>
    <dbReference type="OrthoDB" id="9909019at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883:SF43">
        <property type="entry name" value="PALMITOYLTRANSFERASE APP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883">
        <property type="entry name" value="ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0564">Palmitate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="375"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="405"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="520"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="565"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="13">
        <location>
            <begin position="476"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="658"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="57"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="110"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="163"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="186"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="223"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="302"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="318"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ32719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="688" mass="75645" checksum="B5710E57930EFD02" modified="2011-01-11" version="1">MTSKDQAGGANAPTGNDAFSKPRFTGRSDRPGPPSIISSRMTDIASDDEGEAAAQAPSENNPRSKSAMDSISRPGTAKTGTSGPLEGRRRGPPSRMNYITSLHDKRRSTGAGSTAGSVTSRPPSSTGRSHVPSLTSSAFFRPMSSQKLQAQRGGSRPVTRQQPKLDDVEPEPRQSDAAAAAVASGGPNTRHSVISNPVSNPVARLQRQLTEDSELRPPPSRGTEYTEQGTYDRITANTSPTHGHYAAGSVSESVTPLHQNQRNSRNLSVNVDRGFKERGSQPGSAKSPRSFRSSFLLPIRGDQSQTKSNRSLPGGEKLSSTASTPQLNPTHPTGPANSNSLNKSKSNLGYVFQYFEGNTVFCMGGRFQNTKHRPVNVATGLFIVIPAVLFFIFSAPWLWNNVSPAIPLTFAYLFYICISSFLHASVSDPGILPRNLHAFPPVEPTDDPLRLGPPTNDWTLIKSAESSTAAMEVPVKHCRTCNIWRPPRAHHCRLCDNCIETHDHHCVWLNNCVGRRNYRYFFVFVSSATFLSLYLFGASLGQIIAHQNRSGISFSQSVDDFRVPFAMVIYGLLAFLYPAALMGYHIFLMARGETTREYINSHKFIKKERFRAFTQGSMLKNWVVVLCRPRPPTYYQFKKRYSAGDQRLGAFRDQPKHDAQSMEMQNVRPSAGFQGPVSLRNETNTSTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPZ0</accession>
    <name>E3QPZ0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Serine/arginine repetitive matrix protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08072</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697366">
        <property type="protein sequence ID" value="EFQ32928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096948.1">
        <property type="nucleotide sequence ID" value="XM_008098757.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPZ0"/>
    <dbReference type="STRING" id="645133.E3QPZ0"/>
    <dbReference type="GeneID" id="24413437"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08072"/>
    <dbReference type="eggNOG" id="ENOG502S8Z8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017050_1_0_1"/>
    <dbReference type="OrthoDB" id="5424692at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="352"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="429"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="509"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="643" mass="71689" checksum="481386772FBD599E" modified="2011-01-11" version="1">MDRDRRSRYEDGEVTRYGAGESWRPFPRGGGGDRSPRRVRSPLRDRERDRDRDRDRDRDRDRDRDRDRERLRSRDRDRERDRDPRDRDRPRSRDRDRERARTPPLTSDSYVPGRSPARRRSRSTERYRRDRSRDRDPRPQSDTWRRRDRTRSPPVRRPSPRRSPSRRRSPIGRSPAIRDERSDRARSPPRRDNRDRDRERERDRDLDRRDDRYRSLPPFAHTPVSLAARRRSRSPYGRDRGPRDRTPPPRRSPAPAPRSGYRPRSRSTSRRGGERYLGSSYRRASPPRDSGISSAITSRSASGKSSPHPPPSIRARSRPQSRERGERVEREREQPQQPREREREREPTPLQTGGASAASSSSTTTTTTTTIREAPKPAAAAAAAVAAAAPQEPAPPVAKTPPRGPAALRAPTGPAATRNFSAPAGSPAVQPPRHPQTPSVPPPRADATSPTIPPAGPRGYVAPARGGGYSTRGGRGSWSGPSPRQAPVPTTSPSAIGNGPSAIPTGPRANPSNNTPSNTSTAPKPFNPPTGPSSQHGAGGARPTLAQSMLATLPPIIPGGKIDPSLLPTTMGITREIEPHYKKLKAEEEKARADLDAKQDKLRQSLQMWDKLEMESKAWKTRVDLSEQSLKSLAGEGLGGAAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQ15</accession>
    <name>E3QQ15_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08097</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697366">
        <property type="protein sequence ID" value="EFQ32953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096973.1">
        <property type="nucleotide sequence ID" value="XM_008098782.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQ15"/>
    <dbReference type="STRING" id="645133.E3QQ15"/>
    <dbReference type="GeneID" id="24413462"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08097"/>
    <dbReference type="eggNOG" id="ENOG502SC13">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060131_6_4_1"/>
    <dbReference type="OrthoDB" id="2115692at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052523">
        <property type="entry name" value="Trichothecene_AcTrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791:SF17">
        <property type="entry name" value="ACETYLTRANSFERASE, GNAT FAMILY FAMILY (AFU_ORTHOLOGUE AFUA_8G05690)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791">
        <property type="entry name" value="GNAT FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="204" mass="23197" checksum="6369A94E5017AEBC" modified="2011-01-11" version="1">MAILSALIIEPATLEEVPALTEVWFAAFAHDPEITRLWPDTPRVRAWWDDANRGDMLGKPFQRFVKVVDPGAVDARGRPRVAAWAKWDTSMPARRGRRYPPWCEDMPAEVCDAFFDKEERERARVMGDEEHYYLDTLVTHPDYQRRGAGSMLLKWGCELADEDGVGAYVDASKAGKGLYERFGFVDKSEADAGEVASMVRRRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQD2</accession>
    <name>E3QQD2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">nitric oxide dioxygenase</fullName>
            <ecNumber evidence="4">1.14.12.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">GLRG_08214</name>
    </gene>
    <organism evidence="20">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">In the presence of oxygen and NADH, it has NADH oxidase activity, which leads to the generation of superoxide and H(2)O(2). Under anaerobic conditions, it also exhibits nitric oxide reductase and FAD reductase activities. However, all these reactions are much lower than NOD activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>2 nitric oxide + NADH + 2 O2 = 2 nitrate + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19469"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16480"/>
            <dbReference type="ChEBI" id="CHEBI:17632"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.14.12.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>2 nitric oxide + NADPH + 2 O2 = 2 nitrate + NADP(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19465"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16480"/>
            <dbReference type="ChEBI" id="CHEBI:17632"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.14.12.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.14.12.17" evidence="4"/>
    <dbReference type="EMBL" id="GG697367">
        <property type="protein sequence ID" value="EFQ33070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097090.1">
        <property type="nucleotide sequence ID" value="XM_008098899.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQD2"/>
    <dbReference type="STRING" id="645133.E3QQD2"/>
    <dbReference type="GeneID" id="24413579"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08214"/>
    <dbReference type="eggNOG" id="KOG3378">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003827_12_0_1"/>
    <dbReference type="OrthoDB" id="436496at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008941">
        <property type="term" value="F:nitric oxide dioxygenase NAD(P)H activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071500">
        <property type="term" value="P:cellular response to nitrosative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046210">
        <property type="term" value="P:nitric oxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009636">
        <property type="term" value="P:response to toxic substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08922">
        <property type="entry name" value="FHb-globin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06184">
        <property type="entry name" value="flavohem_like_fad_nad_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.490.10:FF:000003">
        <property type="entry name" value="Flavohemoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000034">
        <property type="entry name" value="Flavohemoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000010">
        <property type="entry name" value="Flavohemoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="entry name" value="Globins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000971">
        <property type="entry name" value="Globin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009805">
        <property type="entry name" value="PRK13289.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43396">
        <property type="entry name" value="FLAVOHEMOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43396:SF3">
        <property type="entry name" value="FLAVOHEMOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00042">
        <property type="entry name" value="Globin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="Globin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01033">
        <property type="entry name" value="GLOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0216">Detoxification</keyword>
    <keyword evidence="9" id="KW-0274">FAD</keyword>
    <keyword evidence="7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="12" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0520">NAD</keyword>
    <keyword evidence="10" id="KW-0521">NADP</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Globin" evidence="17">
        <location>
            <begin position="2"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="18">
        <location>
            <begin position="149"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00056398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS01033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EFQ33070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="424" mass="47189" checksum="1C13A25DC18D8C50" modified="2011-01-11" version="1">MGLTQDQINIVKSTAPVLKVHGETITTLFYKDMIDTHPELKNVFSLRNQASGEQPRALAQSVLAYATYIDDLPKLKAAVERIAHKHASLYIRPEQYDIVGTHLMKAIGEVLGDALTPEIAEAWTAAYAQLAQVFVGRESEMYREAGPWTDWRKFRIIRRVNESDSVTSFYLAPSDGKLPLPKYLPGQYISVRVPVPQLGGITQPRQYSLSDAASRGDCYRISVKREATVVNAPQDDISKGLVPGLVSNLLHDSYQAGDEVEVSHPQGDFFLDTAQADKADVPLVLLSAGVGATPLMSILNTVLGPESKTPSRPVKWVHAARNSGSLVFAKHIRNLTRERENVSAHIFLNEVKPGDQKGQEYDFEQHLDLTRLPQEDLGLADNRTEYYVCGPRDWMLKVRLVLESMGIERGRVKLELFATGDVEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQQ8</accession>
    <name>E3QQQ8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Cutinase</fullName>
            <ecNumber evidence="3 12">3.1.1.74</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_08340</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants. Degrades cutin, a macromolecule that forms the structure of the plant cuticle.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 12">
            <text>cutin + H2O = cutin monomers.</text>
            <dbReference type="EC" id="3.1.1.74"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the cutinase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.74" evidence="3 12"/>
    <dbReference type="EMBL" id="GG697368">
        <property type="protein sequence ID" value="EFQ33196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097216.1">
        <property type="nucleotide sequence ID" value="XM_008099025.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQQ8"/>
    <dbReference type="ESTHER" id="colgm-e3qqq8">
        <property type="family name" value="Cutinase"/>
    </dbReference>
    <dbReference type="GeneID" id="24413705"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08340"/>
    <dbReference type="eggNOG" id="ENOG502S3AW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040058_2_1_1"/>
    <dbReference type="OrthoDB" id="3225429at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050525">
        <property type="term" value="F:cutinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000675">
        <property type="entry name" value="Cutinase/axe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043580">
        <property type="entry name" value="CUTINASE_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043579">
        <property type="entry name" value="CUTINASE_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011150">
        <property type="entry name" value="Cutinase_monf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48250:SF1">
        <property type="entry name" value="CUTINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48250">
        <property type="entry name" value="CUTINASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01083">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00129">
        <property type="entry name" value="CUTINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01110">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00155">
        <property type="entry name" value="CUTINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00931">
        <property type="entry name" value="CUTINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 12" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="6 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005127931" description="Cutinase" evidence="12">
        <location>
            <begin position="21"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="10">
        <location>
            <position position="260"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="100"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="243"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR611150-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR611150-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ33196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="314" mass="32710" checksum="D96A1082BBB9D294" modified="2011-01-11" version="1">MRPSLALLLFAGLLCHQTAALSVPKNRDRDLSRLLSGKLDVLDRVPGLVNKVLSTTILVVRALRETIDDNGETRNDLDTALGFNSTTGLPTGNSTSAVSCPNIAVIYARGTNEPGMSRVLRGNVGFLTGPPFFDALKTYMNGTGTLSIQGVNQYPAEPAGFFAGGSMTGATAAAQVASRTLTMCPNTRLTMSGYSQGSQVARLAIAQLTLDQQARISSVVLFGDPLGGAAVSGVDETRLLVVCHAGDNICEGGNLVLSPHLDYSSDAPTAALFVMQRSNLGLASRDAENEGMSGTVVGKVQGIMLSPKHGIASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRE1</accession>
    <name>E3QRE1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Shugoshin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_08708</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the shugoshin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697370">
        <property type="protein sequence ID" value="EFQ33429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097449.1">
        <property type="nucleotide sequence ID" value="XM_008099258.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRE1"/>
    <dbReference type="STRING" id="645133.E3QRE1"/>
    <dbReference type="GeneID" id="24414073"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08708"/>
    <dbReference type="eggNOG" id="ENOG502SFX7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013723_1_1_1"/>
    <dbReference type="OrthoDB" id="5394106at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000775">
        <property type="term" value="C:chromosome, centromeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045132">
        <property type="term" value="P:meiotic chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011515">
        <property type="entry name" value="Shugoshin_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07557">
        <property type="entry name" value="Shugoshin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Shugoshin C-terminal" evidence="5">
        <location>
            <begin position="472"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="98"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="180"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="530"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="14"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="107"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="132"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="229"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="265"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="314"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="337"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="360"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="382"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="446"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="488"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="530"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="540"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="586"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="599"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="667"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="726"/>
            <end position="735"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ33429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="735" mass="80148" checksum="8DC9A45DD7D89D53" modified="2011-01-11" version="1">MARLNEPPVSADSIDTLRRKLLRQNRDLAKANAIHLARIKNLEADYSRCLSDNIELNGRIIGLEKELENSNARRIADHALDIRSRLETQLMDCMSLIASLGQEPPTKRHASPRGRRISRASLSHRSPPQRRPPREPTKDTEARALQEGRLPPIAENKSYPRATLDREQILALCSEAADITDTTDTTDSPELGPPPLSRFVDTDSVNIGSPHRPLDAAGPETSHSSPMLSPSPAPAPQPAVAPKTTNKSDKAVIVRPDSIPTSEKVQTDTKRPPAEDHSLPPVMPQTTVKVGSKRKYSISDDTIKNSKPVAGLPKPKEPEGRPDAAREQPSGQTLKELANRRREARERMSAPLNPRKPLSAKSTNDDLTSPVKSAKAGADNGKAPEKPKPRAARERAAQKIKEEAEPESPVEVPAASPPPPAPVTEVFPSTETVPTEAALLSPASPEPTSRMSLSSVRDTPPPTDISSRGETSRPSRRARAAVSYAEPNLRDKMRRPTKELYDAVTGQTRYLQRSGSANAEQLFSEGVVVVKRESSEESTWKQISAAMSPSQDAARREKSPNSPANKAKPAEPMLTVVKPLRKKRSSSMMSGSISESEGQRPSQQPPSGASVSGKIIDSQPTPSPERQVDPYEFRTSITASDDSWAESKEDVAPARQSKSSRRLSSVVREDFKVDSTDGAERAKAGGPKKRASMVLPKRSHLEAESLEDSSFESVESGDFPDTRSKSSMRRRSMML</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="95" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRH8</accession>
    <name>E3QRH8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="21">Pentafunctional AROM polypeptide</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="21">3-dehydroquinate synthase</fullName>
                <shortName evidence="21">DHQS</shortName>
                <ecNumber evidence="21">4.2.3.4</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="21">3-phosphoshikimate 1-carboxyvinyltransferase</fullName>
                <ecNumber evidence="21">2.5.1.19</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="21">5-enolpyruvylshikimate-3-phosphate synthase</fullName>
                <shortName evidence="21">EPSP synthase</shortName>
                <shortName evidence="21">EPSPS</shortName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="21">Shikimate kinase</fullName>
                <shortName evidence="21">SK</shortName>
                <ecNumber evidence="21">2.7.1.71</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="21">3-dehydroquinate dehydratase</fullName>
                <shortName evidence="21">3-dehydroquinase</shortName>
                <ecNumber evidence="21">4.2.1.10</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="21">Shikimate dehydrogenase</fullName>
                <ecNumber evidence="21">1.1.1.25</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="27" type="ORF">GLRG_08745</name>
    </gene>
    <organism evidence="28">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="28" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="28">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="20 21 22">The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21 22">
            <text>3-dehydroquinate = 3-dehydroshikimate + H2O</text>
            <dbReference type="Rhea" id="RHEA:21096"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16630"/>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
            <dbReference type="EC" id="4.2.1.10"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21256"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57701"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
            <dbReference type="EC" id="2.5.1.19"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="18">
            <dbReference type="Rhea" id="RHEA:21257"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21 22">
            <text>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate = 3-dehydroquinate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21968"/>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="EC" id="4.2.3.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19 21 22">
            <text>shikimate + ATP = 3-phosphoshikimate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13121"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.71"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21 22">
            <text>shikimate + NADP(+) = 3-dehydroshikimate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17737"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16630"/>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="21 22">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="21 22">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="21 22">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="21 22">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 3/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="21 22">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 4/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 21 22">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 5/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 21 22">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="21 22">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 21 22">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the EPSP synthase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="21 22">In the 2nd section; belongs to the EPSP synthase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="21 22">In the 3rd section; belongs to the shikimate kinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="21 22">In the 4th section; belongs to the type-I 3-dehydroquinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="21 22">In the C-terminal section; belongs to the shikimate dehydrogenase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="22">In the N-terminal section; belongs to the dehydroquinate synthase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="21">In the N-terminal section; belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.4" evidence="21"/>
    <dbReference type="EC" id="2.5.1.19" evidence="21"/>
    <dbReference type="EC" id="2.7.1.71" evidence="21"/>
    <dbReference type="EC" id="4.2.1.10" evidence="21"/>
    <dbReference type="EC" id="1.1.1.25" evidence="21"/>
    <dbReference type="EMBL" id="GG697370">
        <property type="protein sequence ID" value="EFQ33466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097486.1">
        <property type="nucleotide sequence ID" value="XM_008099295.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QRH8"/>
    <dbReference type="GeneID" id="24414110"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08745"/>
    <dbReference type="eggNOG" id="KOG0692">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001201_1_2_1"/>
    <dbReference type="OrthoDB" id="197068at2759"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003855">
        <property type="term" value="F:3-dehydroquinate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003856">
        <property type="term" value="F:3-dehydroquinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003866">
        <property type="term" value="F:3-phosphoshikimate 1-carboxyvinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004764">
        <property type="term" value="F:shikimate 3-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004765">
        <property type="term" value="F:shikimate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00502">
        <property type="entry name" value="DHQase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08195">
        <property type="entry name" value="DHQS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01556">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01065">
        <property type="entry name" value="NAD_bind_Shikimate_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00464">
        <property type="entry name" value="SK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1090.10:FF:000007">
        <property type="entry name" value="Pentafunctional AROM polypeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000135">
        <property type="entry name" value="Pentafunctional AROM polypeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1970:FF:000007">
        <property type="entry name" value="Pentafunctional AROM polypeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001256">
        <property type="entry name" value="Pentafunctional AROM polypeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.65.10.10:FF:000007">
        <property type="entry name" value="Pentafunctional AROM polypeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.65.10.10:FF:000008">
        <property type="entry name" value="Pentafunctional AROM polypeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1090.10">
        <property type="entry name" value="Dehydroquinate synthase-like - alpha domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.10">
        <property type="entry name" value="Enolpyruvate transferase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10860">
        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00210">
        <property type="entry name" value="EPSP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03143">
        <property type="entry name" value="Pentafunct_AroM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00109">
        <property type="entry name" value="Shikimate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018508">
        <property type="entry name" value="3-dehydroquinate_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016037">
        <property type="entry name" value="DHQ_synth_AroB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030960">
        <property type="entry name" value="DHQS/DOIS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056179">
        <property type="entry name" value="DHQS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001381">
        <property type="entry name" value="DHquinase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001986">
        <property type="entry name" value="Enolpyruvate_Tfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036968">
        <property type="entry name" value="Enolpyruvate_Tfrase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006264">
        <property type="entry name" value="EPSP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023193">
        <property type="entry name" value="EPSP_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008289">
        <property type="entry name" value="Pentafunct_AroM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031322">
        <property type="entry name" value="Shikimate/glucono_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013708">
        <property type="entry name" value="Shikimate_DH-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010110">
        <property type="entry name" value="Shikimate_DH_AroM-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000623">
        <property type="entry name" value="Shikimate_kinase/TSH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023000">
        <property type="entry name" value="Shikimate_kinase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01356">
        <property type="entry name" value="aroA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01357">
        <property type="entry name" value="aroB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01093">
        <property type="entry name" value="aroD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01809">
        <property type="entry name" value="Shik-DH-AROM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21090">
        <property type="entry name" value="AROM/DEHYDROQUINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21090:SF5">
        <property type="entry name" value="PENTAFUNCTIONAL AROM POLYPEPTIDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01761">
        <property type="entry name" value="DHQ_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24621">
        <property type="entry name" value="DHQS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01487">
        <property type="entry name" value="DHquinase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00275">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08501">
        <property type="entry name" value="Shikimate_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01202">
        <property type="entry name" value="SKI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000514">
        <property type="entry name" value="Pentafunct_AroM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01100">
        <property type="entry name" value="SHIKIMTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56796">
        <property type="entry name" value="Dehydroquinate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="EPT/RTPC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01028">
        <property type="entry name" value="DEHYDROQUINASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00104">
        <property type="entry name" value="EPSP_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00885">
        <property type="entry name" value="EPSP_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01128">
        <property type="entry name" value="SHIKIMATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 21 22" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="15 21 22" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="12 21" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 21 22" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 21 22" id="KW-0418">Kinase</keyword>
    <keyword evidence="16 21 22" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 21 22" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17 21" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="13 21" id="KW-0521">NADP</keyword>
    <keyword evidence="9 21" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14 21 22" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="28" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 21 22" id="KW-0808">Transferase</keyword>
    <keyword evidence="11 21 22" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="3-dehydroquinate synthase N-terminal" evidence="24">
        <location>
            <begin position="81"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="3-dehydroquinate synthase C-terminal" evidence="26">
        <location>
            <begin position="195"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="Enolpyruvate transferase" evidence="23">
        <location>
            <begin position="403"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="domain" description="Shikimate dehydrogenase substrate binding N-terminal" evidence="25">
        <location>
            <begin position="1287"/>
            <end position="1367"/>
        </location>
    </feature>
    <feature type="region of interest" description="3-dehydroquinate synthase" evidence="21">
        <location>
            <begin position="1"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Shikimate dehydrogenase" evidence="21">
        <location>
            <begin position="1282"/>
            <end position="1579"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for 3-dehydroquinate synthase activity" evidence="21">
        <location>
            <position position="261"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for 3-dehydroquinate synthase activity" evidence="21">
        <location>
            <position position="276"/>
        </location>
    </feature>
    <feature type="active site" description="For EPSP synthase activity" evidence="21">
        <location>
            <position position="820"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for 3-dehydroquinate dehydratase activity" evidence="21">
        <location>
            <position position="1172"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity" evidence="21">
        <location>
            <position position="1200"/>
        </location>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <begin position="53"/>
            <end position="55"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <begin position="87"/>
            <end position="90"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <begin position="118"/>
            <end position="120"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
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        </ligand>
    </feature>
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            <position position="123"/>
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        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate</name>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
        </ligand>
    </feature>
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        <location>
            <begin position="143"/>
            <end position="144"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
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        </ligand>
    </feature>
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        <location>
            <position position="150"/>
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        <ligand>
            <name>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate</name>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="156"/>
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        <ligand>
            <name>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate</name>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="165"/>
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        <ligand>
            <name>NAD(+)</name>
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        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="166"/>
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        <ligand>
            <name>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate</name>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
        </ligand>
    </feature>
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        <location>
            <begin position="183"/>
            <end position="186"/>
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        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
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        <location>
            <position position="194"/>
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        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
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        <location>
            <begin position="198"/>
            <end position="201"/>
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        <ligand>
            <name>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate</name>
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        </ligand>
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    <feature type="binding site" evidence="21">
        <location>
            <position position="198"/>
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        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
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        <location>
            <position position="251"/>
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        <ligand>
            <name>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate</name>
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        <location>
            <begin position="265"/>
            <end position="269"/>
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            <name>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate</name>
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        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate</name>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
        </ligand>
    </feature>
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        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
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        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate</name>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="357"/>
        </location>
        <ligand>
            <name>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate</name>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <begin position="868"/>
            <end position="875"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00004811"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00004842"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00009948"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00044633"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00048567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00054455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="PIRNR" id="PIRNR000514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF00275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF01761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="Pfam" id="PF08501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="Pfam" id="PF24621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="EMBL" id="EFQ33466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1579" mass="170195" checksum="65C12805E133D6BD" modified="2011-01-11" version="1">MGLANGSGSGTGPTRITILGKDDIVVDHGIWLNFVTHDLLENLKTSTYVIITDTNLYDTYVPPFQKVFNATASASTRLLTYAIPPGEISKSRQTKASIEDWMLSQKCTRDTVIIALGGGVIGDMIGYVAATFMRGVRFVQVPTTLLSMVDSSIGGKTAIDTPAGKNLVGAFWQPSRIYIDLAFLETLPTREFINGMAEVVKTAAIWDEDEFTTLESNAATVLAAIKSQGPQRLSSIRDVLKRIVLGSARVKAHVVSSDEREGGLRNLLNFGHSIGHAYEALLTPQLLHGEAVAIGMVKEAELARYLGVLRPGAVARLVKCIASYELPTSIHDKKVVKLTAGKASPVDALLEKMAVDKKNDGAKKKIVLLSAIGRTHEQKASVVEDGAIRVVLSPATQVIPGVPKSLHTTVTPPGSKSISNRALVLAALGQGTCCITNLLHSDDTEYMLSAIAQLGGATYAWEDAGEVLAVQGKGGRLSASKKALYLGNAGTASRFLTTVVALCAPSDVSSTVLTGNARMKVRPIGPLVDALRANGLGIKYLGQEKSLPLQVDAADGFEGGVIELAATISSQYVSSILMAAPYAKNPVTLRLVGGKPISQFYIDMTIAMMRTFGVNVTKSAEEPNTYHVPKAVYQNPPEYVVESDASSATYPLAIAAITGTTCTVPNIGSDSLQGDSRFAVDVLRPMGCTVEQTGTSTTVTGPPIGSLKAIEHVDMEPMTDAFLTASVLAAVASGTTRISGIANQRVKECNRIGVMREQLAKFGVETDEFDDGIIVNGRSVQSLQGPTEGIFCYDDHRVAMSFSVLSVVAPKPVTILERECTGKTWPGWWDTLSQSFKVILDGVDQHPQAGATGPSAKTRKDKSVFIIGMRGAGKTTAGRWMANTLKRPFVDLDEELERRAGMTIPEMIRGTRGWDGFRADELELLREVLEKQSHGYIFSCGGGIVETPEARKLLVAHCRNDGTVLLVHRNTKEVVEYLLQDKSRPAYREDIEDVYYRRKPFFEECSNFEYFSPHPPGTLATRDPPLDFRRFVNTLCGEEVQVKRALAKDPSFFVSLTVPEVASALALIPAVVVGSDAVELRVDLLQDYSEESVAHQVALLRSVANVPIIFTLRTKAQGGRFPDDAYDQGLGLYQKAIRMGVEFIDVEMTLPEQVIQAVVENKGLCRIIASHHDPQGKLSWKDGSWIPFYNKALQWGDVIKLVGIAQHIEDNYALAQFKSAMLSSHKTPIIALNMGTAGKLSRVFNGCLTPVSHPDLPFKAAPGQLSAAEIRKALALLGGISPQSFYLFGKPISASRSPALHNTLFALTGLPHRYLLKETDSAADVREAIRAPDFGGASVTIPLKLDIMKEIDEISESARIIGAVNTIIPVRDNGDVNAKLVGDNTDWSGMVHSLQSAGVASRSATGVQRSAMVIGSGGTTRAAIFALHALGFGPIYALARNSSNLETLKASFPPEYRIEALKSASEASTLPSSPTVMVSTIPADKPVDPSLRETLAVVLRHEPATEEKRVLLEMAYMPRYTPLMQLAEEAGWATIPGLEVLSAQGWYQFQKWTDIIPLYQTARAAVLGEEAGEATGRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>E3QS75</accession>
    <name>E3QS75_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Nucleoporin NUP49/NSP49</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_08958</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697373">
        <property type="protein sequence ID" value="EFQ33814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097834.1">
        <property type="nucleotide sequence ID" value="XM_008099643.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QS75"/>
    <dbReference type="STRING" id="645133.E3QS75"/>
    <dbReference type="GeneID" id="24414323"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08958"/>
    <dbReference type="eggNOG" id="KOG0845">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027081_1_0_1"/>
    <dbReference type="OrthoDB" id="2538017at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008139">
        <property type="term" value="F:nuclear localization sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025574">
        <property type="entry name" value="Nucleoporin_FG_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024882">
        <property type="entry name" value="NUP58/p45/49"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13437">
        <property type="entry name" value="NUCLEOPORIN P58/P45 NUCLEOPORIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13437:SF2">
        <property type="entry name" value="NUCLEOPORIN P58_P45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13634">
        <property type="entry name" value="Nucleoporin_FG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="6" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="16"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="50"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="77"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="97"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="145"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="184"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ33814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="455" mass="47877" checksum="A09A6BFF9B2E2D0A" modified="2011-01-11" version="1">MFGRSASATGGGLSINTGAANSAAGSSSTPAAGGLFGNAAASTQPAASGGLFGGTQTGGGGLFGNKPAAPATGGLFGQSQSATPSQPQQSGGGGLFGSAQPQQQQQQPQQQQSGGLFGSAQPQQQQGGGLFGASQQKPATGGLFGQSSTQPQQQQQQQQPSGGLFGGGNTQPQQNQGAGGGLFGQSQAQNQSKPGGLFGQSQAGNNSSAPGLTMGQSTTQQTVPGVRVDVSNIKGTTRFNDLEQSIQTEMENCDMMIQRFMAHASEIRGFMAAHGGDLEQLTTDVNWLQRKYEGVKTTLDEDIVTMAHLKDLVKSDADIAKMAFAGADQLKLPAHYHQTWLTRGGSGNNTTNGSQDRNVEDVLTLFSNEADRLKELHQFQVQKIKEMEQHMPGVEHGLYERVRALRDQTQLPAFNMVLDLLETIKMMGDKIYEAADAIVDVREKLTKLQRQYPTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTB2</accession>
    <name>E3QTB2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_09244</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697376">
        <property type="protein sequence ID" value="EFQ34100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098120.1">
        <property type="nucleotide sequence ID" value="XM_008099929.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTB2"/>
    <dbReference type="STRING" id="645133.E3QTB2"/>
    <dbReference type="GeneID" id="24414609"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09244"/>
    <dbReference type="eggNOG" id="ENOG502SSB8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046870_5_2_1"/>
    <dbReference type="OrthoDB" id="444631at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF162">
        <property type="entry name" value="SATRATOXIN BIOSYNTHESIS SC1 CLUSTER PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="255"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="289"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="41"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="323"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="323"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="349"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="392"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ34100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="436" mass="49669" checksum="1363BED0420A82AD" modified="2011-01-11" version="1">MSSPAADPDAVLFGAAQNINGRTLVAIGWGNASASFIFLLFRLLIRWRRNRRLLLDDYCIILGWLCLLSLAVIQMEQTGPMYYLIHLQAGRLIPTSLQEVSQQTEQWLRWSHAMNYIYWTGLWAVKASILTVFFHLVSPVPVLRKAWYSVAAFTLLTYIGGWVTGSLICDRFSDSFVAGKIPMSFLPPWTADDRLPQLSSDSAIVTGKCNSPSELDRVRYSAYYAAAVDIATDLMIMALPIAMLPSLKLEIRKKLGLAVAFSLALITILIAVVRMTQVMKGHTLDKVGLSIWSITELGVSIIVGSLPPLRILFTSGFRKYNRGKKAGHRSSAKHRDGNGNNPNSPTIKMLEKYDKNRDDELRRAKEEREEASRRAREEAREWAEASTPSQRIRQDMERAREQARAENEARARERERERERERERERSTERGRQRNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTP2</accession>
    <name>E3QTP2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Monocarboxylate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09348</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697378">
        <property type="protein sequence ID" value="EFQ34204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098224.1">
        <property type="nucleotide sequence ID" value="XM_008100033.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTP2"/>
    <dbReference type="GeneID" id="24414713"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09348"/>
    <dbReference type="eggNOG" id="ENOG502RM0T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_657217_0_0_1"/>
    <dbReference type="OrthoDB" id="2426273at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39596">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39596:SF3">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="418" mass="47201" checksum="3041B193372440DD" modified="2011-01-11" version="1">MVSEETDSRLRLQEMLQRHGIGSRRAMITSNRELSRWEVADVEAVLHQVGLRGHDYNPCGREFNQYRGLGLGSKVFMYSCIGGGFALAIPILIVHSTIRLFKQHTFAVFRQTWNEYGLSNLLALGFDFDRYIKAPLNLVQQSVDQKAALCVNADGNFKVLHDGYSVMSHVWEETMGWNNPEGFGKVDLSLRKKGIHKAHFRKFFDRCGVMWLWMDVLAMPEVLEDMSPQQQSETKALRVGVINNLNSIYRNADKVVVLDSLVLQLKTGSLVDVAVVLCLGRWITRMWTLAEARLGRRVLIKTEDGETDLDEVIALLEGDMLGPSPRYDGLAKTLSAKRGNIPLRTRYDLADLTAAYKFGQTGEAIDNVRSVYPLLDLKWEVGWDERQAVLNLKETLPAESDALSTFCTDRGLPDPFDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUX5</accession>
    <name>E3QUX5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Feruloyl esterase C</fullName>
            <ecNumber evidence="11">3.1.1.73</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Ferulic acid esterase C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_09807</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 11">Involved in degradation of plant cell walls. Hydrolyzes the feruloyl-arabinose ester bond in arabinoxylans, and the feruloyl-galactose ester bond in pectin. Active against paranitrophenyl-acetate, methyl ferulate and wheat arabinoxylan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>feruloyl-polysaccharide + H2O = ferulate + polysaccharide.</text>
            <dbReference type="EC" id="3.1.1.73"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the faeC family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.73" evidence="11"/>
    <dbReference type="EMBL" id="GG697382">
        <property type="protein sequence ID" value="EFQ34663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098683.1">
        <property type="nucleotide sequence ID" value="XM_008100492.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUX5"/>
    <dbReference type="STRING" id="645133.E3QUX5"/>
    <dbReference type="ESTHER" id="colgm-e3qux5">
        <property type="family name" value="FaeC"/>
    </dbReference>
    <dbReference type="GeneID" id="24415172"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09807"/>
    <dbReference type="eggNOG" id="ENOG502QU71">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027551_2_0_1"/>
    <dbReference type="OrthoDB" id="424610at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030600">
        <property type="term" value="F:feruloyl esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043595">
        <property type="entry name" value="FaeB/C/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38050:SF1">
        <property type="entry name" value="FERULOYL ESTERASE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 11" id="KW-0732">Signal</keyword>
    <keyword evidence="4 11" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5027148520" description="Feruloyl esterase C" evidence="11">
        <location>
            <begin position="22"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="13">
        <location>
            <begin position="294"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="265"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00034075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU367094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ34663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="325" mass="33504" checksum="D8B8D4D797DCDC54" modified="2011-01-11" version="1">MASFSAIVLLLLSVSLGSVMAATPGCGKAAPASGTKSIGSRRYILQVPANYNPNKEYMLIFGFHWLNGNMNTVAPGYYGLRALAGESAIFVAPDGLNAGWANNGGADVTFVDQILSEVQNSLCVDTTKRFATGFSYGGAMSNAVACARPNIFRAVSVIAGAQLSGCDGGTTPVAYLGIHGSADNVLPIAQGRALRDRFLGVNKCQSKTAPDPSPGSSQHIKTEYSCSAGYPVWWIGHGGGHVGDANDSQGNWMARETWDFFTKAIYGGGSAPPPANTSPPSSTPTTAPPPSGGQCAAKFGQCGGSGWTGPTCCQSGSTCNAQNQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QV86</accession>
    <name>E3QV86_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome P450 monooxygenase ABA1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Abscisic acid biosynthesis protein 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Cytochrome P450 monooxygenase aba1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_09834</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Hormone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697383">
        <property type="protein sequence ID" value="EFQ34690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098710.1">
        <property type="nucleotide sequence ID" value="XM_008100519.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QV86"/>
    <dbReference type="STRING" id="645133.E3QV86"/>
    <dbReference type="GeneID" id="24415199"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09834"/>
    <dbReference type="eggNOG" id="KOG0158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_0_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11060">
        <property type="entry name" value="CYP57A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000076">
        <property type="entry name" value="Cytochrome P450 monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF236">
        <property type="entry name" value="PISATIN DEMETHYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-0349">Heme</keyword>
    <keyword evidence="6 12" id="KW-0408">Iron</keyword>
    <keyword evidence="5 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0843">Virulence</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="123"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="12">
        <location>
            <position position="461"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00067672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00068222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00079990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ34690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="517" mass="57876" checksum="6D6D055F8525E349" modified="2011-01-11" version="1">MIMGFSSDLYGLRWPFALAVLLLYAGHKIRTYNRLKAFKGPSLCGWTEAWHVWAILSFRSHLKYDGVCRKYGTIARVGPNDLVTSSPELLAHMSGIRSQYTRTEWYYRACRHMPDKDHVFSEMDEKRHKRLRQQTGSGYSGRENPGLEESVDSHVSDLIRLIRSKYTSTEAASRPMDLAQKIQYLTLDVISDISFGKAFGDLRVDDDVFGIAASADTGMIVFTYKIALGLYKILQSPLAARLFGPRETDATGWGRMFANGRAIVKARLALDTQKRSDMIASFIRHGLSEEEILSEATLQMIAGSDTTAASLRAVMLYLITNPRVHAKLRAEIDAFVGSAAAEAAGAARAPGIVSDADARTMPYLQAVIKEGMRVHPPVTNMDPKRVPDGGDTVVVDGRPVFLPGGTNISCAAWPLHLDKGIFGDDAELFRPERWLLETDEKRLMAMHRVHELMFGYGKYQCLGRPIAMMEISKTVFELVRNFDWCLAKPDMPWKESNHAGIFIQTDMWVLASERPSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVZ1</accession>
    <name>E3QVZ1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10173</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697387">
        <property type="protein sequence ID" value="EFQ35029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099049.1">
        <property type="nucleotide sequence ID" value="XM_008100858.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVZ1"/>
    <dbReference type="GeneID" id="24415538"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10173"/>
    <dbReference type="HOGENOM" id="CLU_2359603_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="96" mass="10885" checksum="66E09DE97D5ACCE5" modified="2011-01-11" version="1">MKQAPSTEPLRKKDCPTLHRQYPSPKRPERQPVRLKGLSSSPRGGTITNSQPRTEEVSVEEPRVTPIQRPERRPRVKGGKIRKRYVPTALCAFGIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QW21</accession>
    <name>E3QW21_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">OBG-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_10203</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697387">
        <property type="protein sequence ID" value="EFQ35059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099079.1">
        <property type="nucleotide sequence ID" value="XM_008100888.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QW21"/>
    <dbReference type="STRING" id="645133.E3QW21"/>
    <dbReference type="GeneID" id="24415568"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10203"/>
    <dbReference type="eggNOG" id="KOG1491">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037276_1_0_1"/>
    <dbReference type="OrthoDB" id="545683at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04938">
        <property type="entry name" value="TGS_Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01899">
        <property type="entry name" value="Ygr210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.470:FF:000001">
        <property type="entry name" value="GTP-binding protein homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013646">
        <property type="entry name" value="YGR210-like_G4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23305">
        <property type="entry name" value="OBG GTPASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23305:SF1">
        <property type="entry name" value="OBG-TYPE G DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08438">
        <property type="entry name" value="YGR210-like_G4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="3">
        <location>
            <begin position="5"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ35059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="417" mass="45277" checksum="9A21A65DC22BA557" modified="2011-01-11" version="1">MPRDPLIGLVGKPSAGKSTTLNSLTDASSKVGNFPFTTIDPQRAIGYLQIDCACARYNVSDRCRPNYGACVDGRRSVPIELLDVAGLVPGAHQGKGLGNKFLDDLRHADALIHVVDASGTVDAEGKETRGYDPSVDIAWLRGEIVAWIRGNLMEKWGSIRRRHMAIKATAVDTLQGQFSGYGSTSNVVARALDRLGIKEPLEDWDAETIDRVVNAFTDEKFPTVIALNKIDHPDADKNISKIAKMQDPNTIVLCSAISEIFLRKMAKQGYIKYTEGSEFVDTREDLIEQGDPTGGGLKELDEKNRNRIENLKDMVLYRFGSTGVVQVLSKAAEILGLVPIFPVRNTTSFSSGASDSRFVFRDCVLVKKGTTVGEAARKVMGDAPIAYIEGAGGQRVAEDDLVAVGKNDVLSFKVGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWV0</accession>
    <name>E3QWV0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PPPDE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10482</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697391">
        <property type="protein sequence ID" value="EFQ35338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099358.1">
        <property type="nucleotide sequence ID" value="XM_008101167.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWV0"/>
    <dbReference type="STRING" id="645133.E3QWV0"/>
    <dbReference type="GeneID" id="24415847"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10482"/>
    <dbReference type="eggNOG" id="ENOG502RY7N">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053718_1_0_1"/>
    <dbReference type="OrthoDB" id="3431913at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="327" mass="36540" checksum="F488A91528239E33" modified="2011-01-11" version="1">MSQPGSDEEAKRKRDKVGEFLKKNITKGELAVKHAIGLGATPNVIPVTQPILDGPPRVVEVGWHPVGGLAGKWFAEETGLGKMITEKINKYPDPTQHWAVLVGDFAHQLWMDENFHVIYTNERYKRDEWRTFTVGETRFNDDAIRRAGEYVIQSIRSRHPAYNLISNNCQTYVLELLDAVKVDGQKDFGTTLAVYERLFSSGKVIDLFNGQQRPEQQQQHLLEAPPLQYPPLPPSPASPQGGVAPPQYQYNLPPPPPPPPPPRPCGDPLAHHPGTVSHAQKVMNDNTTQLDTQEEASKPRGFSMGTKEIKEAKRGFLSRFTRKGSSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWY0</accession>
    <name>E3QWY0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Endo-chitosanase</fullName>
            <ecNumber evidence="10">3.2.1.132</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_10512</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Chitosanase catalyzing the endo-type cleavage of chitosan, the deacylated form of chitin. Chitosanase may be crucial in the degradation of the deacetylated portion of chitin in the fungal cell wall.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Endohydrolysis of beta-(1-&gt;4)-linkages between D-glucosamine residues in a partly acetylated chitosan.</text>
            <dbReference type="EC" id="3.2.1.132"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycosyl hydrolase 75 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.132" evidence="10"/>
    <dbReference type="EMBL" id="GG697392">
        <property type="protein sequence ID" value="EFQ35368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099388.1">
        <property type="nucleotide sequence ID" value="XM_008101197.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWY0"/>
    <dbReference type="STRING" id="645133.E3QWY0"/>
    <dbReference type="GeneID" id="24415877"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10512"/>
    <dbReference type="eggNOG" id="ENOG502S39Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046555_1_0_1"/>
    <dbReference type="OrthoDB" id="4756206at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016977">
        <property type="term" value="F:chitosanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009939">
        <property type="entry name" value="Chitosanase_fungal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42061">
        <property type="entry name" value="ENDO-CHITOSANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42061:SF6">
        <property type="entry name" value="ENDO-CHITOSANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07335">
        <property type="entry name" value="Glyco_hydro_75"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ35368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="227" mass="23932" checksum="DBAA4B0654807BA4" modified="2011-01-11" version="1">MHFVYCGDFVDKYKIIYLQGRGGNLANMDVDCDGAQGGGDGRCGSSTDTQSETTFRDVLRGYNTGQQDLNASLHPYVVFGNEGTKSGWPTFDPSQHGVKPLSVMAVICNNQVVYGVWGDTNGDDGPQAMIGEASISLATACYGDVINGNSGHDENDVLYIAFTGDEAVPGAQGAAWNATNYNDFESSITDLGNTLLSRVGSGCNGGLGIEKWLLYTAVLVGSVVLAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXH2</accession>
    <name>E3QXH2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Prenyltransferase and squalene oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_10704</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein prenyltransferase subunit beta family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697395">
        <property type="protein sequence ID" value="EFQ35560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099580.1">
        <property type="nucleotide sequence ID" value="XM_008101389.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXH2"/>
    <dbReference type="STRING" id="645133.E3QXH2"/>
    <dbReference type="GeneID" id="24416069"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10704"/>
    <dbReference type="eggNOG" id="KOG0367">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028946_2_0_1"/>
    <dbReference type="OrthoDB" id="24893at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005953">
        <property type="term" value="C:CAAX-protein geranylgeranyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004662">
        <property type="term" value="F:CAAX-protein geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045089">
        <property type="entry name" value="PGGT1B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001330">
        <property type="entry name" value="Prenyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774:SF4">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE-1 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00432">
        <property type="entry name" value="Prenyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Prenyltransferase alpha-alpha toroid" evidence="8">
        <location>
            <begin position="9"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ35560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="434" mass="47572" checksum="86AB84B94C14B188" modified="2011-01-11" version="1">MTADTAIPLEKARHIKYWQRCHKTFLPHQYTSSDSTRIALSFFILAALDILSPPEPSKEEPHLLTPTDRAAARNFVLGLYHPGGGFCGSPNHALPAELYEDWDFGKGKPRTRNSSSANLASTYFALLILAIVADGPETAENAFAGVDRAATLRWLKRLQRPDGSFGELVLDDGSIEGGNDMRLCFLAATIRWALRGDVKEGDADWVEDIDVDALVRHIRQGQTYDGGLAQSSHQNESHAGYAWCAVSALVLLDRPPQQGAKHHVSETLKQGVPDVSLLIRFLVYRQFEYLEKDDDSDDPDTANFALPESLAGLSLDPNLRFVGFNGRCNKVADTCYCWWVGGTLQMLDCAGLIDAGPSRRFIMSKTQHLIGGFSKYPGGPPDIYHGFLGLAALAIMGDPALKPFDASVCATQETVDKVVAAREGLRDAAKARRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QY51</accession>
    <name>E3QY51_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Lipocalin-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_10984</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the calycin superfamily. Lipocalin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697400">
        <property type="protein sequence ID" value="EFQ35789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099809.1">
        <property type="nucleotide sequence ID" value="XM_008101618.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QY51"/>
    <dbReference type="STRING" id="645133.E3QY51"/>
    <dbReference type="GeneID" id="24416349"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10984"/>
    <dbReference type="eggNOG" id="KOG4824">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_122461_0_0_1"/>
    <dbReference type="OrthoDB" id="565904at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19438">
        <property type="entry name" value="lipocalin_Blc-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022271">
        <property type="entry name" value="Lipocalin_ApoD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047202">
        <property type="entry name" value="Lipocalin_Blc-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000566">
        <property type="entry name" value="Lipocln_cytosolic_FA-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612:SF34">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08212">
        <property type="entry name" value="Lipocalin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036893">
        <property type="entry name" value="Lipocalin_ApoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50814">
        <property type="entry name" value="Lipocalins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013437999" evidence="2">
        <location>
            <begin position="20"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Lipocalin/cytosolic fatty-acid binding" evidence="3">
        <location>
            <begin position="52"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR036893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ35789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="201" mass="21233" checksum="51E4E6A7251E72E2" modified="2011-01-11" version="1">MRPSALLTVLSCAAIATAAATANETAPEPAVPNVVQSTWDGRCFYPAPDAAFDLEAYLGRWYQVAGTLAPFTASCKCIFAQYSLNDNGTVKVNNTCEAGGRAVNILGTAAPADPSYGAKGVLRVQFPGQPGPSCAGPNYIVQDYTPDFALVQSNNFTTLFVLSRQQNPEEAVLDAWIARAGQLGSNLDDVVKTDQTGCKFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QY80</accession>
    <name>E3QY80_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">alpha-amylase</fullName>
            <ecNumber evidence="4">3.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">GLRG_10927</name>
    </gene>
    <organism evidence="20">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endohydrolysis of (1-&gt;4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1-&gt;4)-alpha-linked D-glucose units.</text>
            <dbReference type="EC" id="3.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.1" evidence="4"/>
    <dbReference type="EMBL" id="GG697401">
        <property type="protein sequence ID" value="EFQ35818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099838.1">
        <property type="nucleotide sequence ID" value="XM_008101647.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QY80"/>
    <dbReference type="STRING" id="645133.E3QY80"/>
    <dbReference type="GeneID" id="24416292"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10927"/>
    <dbReference type="eggNOG" id="KOG0471">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006462_7_2_1"/>
    <dbReference type="OrthoDB" id="204980at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004556">
        <property type="term" value="F:alpha-amylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11319">
        <property type="entry name" value="AmyAc_euk_AmyA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000120">
        <property type="entry name" value="Alpha-amylase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013777">
        <property type="entry name" value="A-amylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015340">
        <property type="entry name" value="A_amylase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10357:SF208">
        <property type="entry name" value="ALPHA-AMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10357">
        <property type="entry name" value="ALPHA-AMYLASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09260">
        <property type="entry name" value="A_amylase_dom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001024">
        <property type="entry name" value="Alph-amyl_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8 14" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="16" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="17" id="KW-0732">Signal</keyword>
    <keyword evidence="16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180933" description="alpha-amylase" evidence="17">
        <location>
            <begin position="21"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="505"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="18">
        <location>
            <begin position="33"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="12">
        <location>
            <position position="226"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="12">
        <location>
            <position position="250"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="317"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="364"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="13">
        <location>
            <position position="317"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="50"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="170"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="260"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="458"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001024-1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PIRSR" id="PIRSR001024-2"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PIRSR" id="PIRSR001024-4"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PIRSR" id="PIRSR001024-5"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EFQ35818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="529" mass="58262" checksum="E7BA52DBD820F369" modified="2011-01-11" version="1">MRTSTFAWAALSALSALVSAADLEAWKSRAIYQVMIDRYAHDDGSTDHNCTLYDFCGGTWKGLMNKLDYIQDMGFTAVQISPIVKNIDDNTAVGEAYHGYWSLDNYALSDKFGTKEDLDALVAELHKRDMYLMVDVVVNNMVQKLDSLPPKLDYSKFNPFNDEKYFHPYCNVTEWDNSTNYQDCWLYPYGVALADLATETAPVYTEFSKWIKELVSNYSIDGLRIDAAKHVNDAFLPTFVNASGVFAFGEVLTGYTPDFCRYQTLNLLPGMPNYLEYYPLNSVFFGGDMNSLADLRSQARDGCTDIFALGSFVENHDMPRFAVHNEDMALAKNAMAYILLTDGIPTVYQGQEQHFNGNSTPFNREPLWQSKYDTEAPLYTLTSTLLKTRNQLQKMNSAFATTASEQLFVEDTHLCLRKGPDGAQVVFCITNKSSKGDSYTLSMGGFNPGDQVVEVLSCATSTADGNGNVTLFMDKGEPKAVVPVSVLNGTSICANGTKEAGKDNAAAGLGGSLTLVLASVMAASFALLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYG8</accession>
    <name>E3QYG8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11014</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EFQ35906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008101735.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYG8"/>
    <dbReference type="GeneID" id="24416379"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11014"/>
    <dbReference type="HOGENOM" id="CLU_2558174_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="82" mass="8778" checksum="B5A5597BD34D65B4" modified="2011-01-11" version="1">MSIAADKALQVCKQAQESQGGRSGSQPRAKKVQRTASHRPSGKPAATRAADSQSEGTWQSMRQGMAGKPSRWCIETGTKGQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYS5</accession>
    <name>E3QYS5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_11157</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EFQ36013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100033.1">
        <property type="nucleotide sequence ID" value="XM_008101842.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYS5"/>
    <dbReference type="STRING" id="645133.E3QYS5"/>
    <dbReference type="GeneID" id="24416522"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11157"/>
    <dbReference type="eggNOG" id="KOG1575">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2049528_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ36013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="120" mass="12421" checksum="50E20F3608108DA3" modified="2011-01-11" version="1">MAGSSHLNSALAAGLGSARQRGIGTRVNGSRQDALPTLHNFGIDLIDIAEASITGQLAGGLPRNNVVVHIEYCSTPMKTTSFAHPVVGPVISLRGSLGRAGLGRTDIYPVQGLSHLQACH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYX8</accession>
    <name>E3QYX8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Taurine catabolism dioxygenase TauD/TfdA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_11210</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697407">
        <property type="protein sequence ID" value="EFQ36066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100086.1">
        <property type="nucleotide sequence ID" value="XM_008101895.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYX8"/>
    <dbReference type="STRING" id="645133.E3QYX8"/>
    <dbReference type="GeneID" id="24416575"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11210"/>
    <dbReference type="eggNOG" id="ENOG502QRUR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1081839_0_0_1"/>
    <dbReference type="OrthoDB" id="408743at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050411">
        <property type="entry name" value="AlphaKG_dependent_hydroxylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696">
        <property type="entry name" value="GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696:SF21">
        <property type="entry name" value="TAUD_TFDA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="2">
        <location>
            <begin position="7"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ36066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="222" mass="25241" checksum="3B5DBE2747A23F46" modified="2011-01-11" version="1">MYSRYTRFPSNIHFYCCGNIGGATPIAHSANVFEKVESEIPELVEEIHKRGLGMKMVFRAPGDEAKVNPFNWAGEHSFGQELLPGDDEATTRQKVEQQVRKLTPDFKWKDDGSLELTQHIPDIPCIYGGETPIPRQLLDKLIEVIDKEEINLVMEEGDLLFVDNFQVSHGRQPWEGDRLVLVSMWDTESPIGVFDDTELAMASEWEVTLGFVTRMLRSGSRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYY0</accession>
    <name>E3QYY0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short chain dehydrogenase/reductase family oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11212</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697407">
        <property type="protein sequence ID" value="EFQ36068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100088.1">
        <property type="nucleotide sequence ID" value="XM_008101897.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYY0"/>
    <dbReference type="GeneID" id="24416577"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11212"/>
    <dbReference type="eggNOG" id="KOG1611">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_9_1_1"/>
    <dbReference type="OrthoDB" id="7289984at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051468">
        <property type="entry name" value="Fungal_SecMetab_SDRs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544:SF26">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY OXIDOREDUCTASE (JCVI)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="256" mass="27112" checksum="B07718EF0F7E69ED" modified="2011-01-11" version="1">MASTVYVITGTNKGIGLGLLKALLARPSTTIVASVRNEEAAASLRSAIADVARGNDTELHIMLLDFTKAPTPAAVIEAFKRATLGTIDRVDVLISNAASPFPMTPTHATSAEDLRSAFEINTIAPLMVFQGLWPLMEKSRGPGNVSAKFIGITSSVGSIGSQELFPAGAYGPSKAALNWLIMSLHVQHESLISLAIHPGWVQTYMGNYAAKEWNYEAGPPDTIDSSVNGVLAVMDGATRETTSGKFVTQTGQVLPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZ60</accession>
    <name>E3QZ60_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycoside hydrolase family 16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_11292</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697411">
        <property type="protein sequence ID" value="EFQ36148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100168.1">
        <property type="nucleotide sequence ID" value="XM_008101977.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZ60"/>
    <dbReference type="STRING" id="645133.E3QZ60"/>
    <dbReference type="GeneID" id="24416657"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11292"/>
    <dbReference type="eggNOG" id="ENOG502S39Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077989_1_0_1"/>
    <dbReference type="OrthoDB" id="4524534at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180047" evidence="1">
        <location>
            <begin position="26"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="2">
        <location>
            <begin position="23"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ36148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="222" mass="24224" checksum="6597D97B434E4B91" modified="2011-01-11" version="1">MLCFNQVILLFAGALLVADVIPVGASKTVIPKGSFDSQADFDSHWNYLYPWGSDHNGGARMTKDNVNVDKGTLTLTATKVSGQPPATHGGQQIAINYLSGAIHAKEHFNVSRGGGYDFTAEVKATTTKGTWPAFWLTAVQGWPPEIDMAEWKGSGKISFNTFNTSSIVAAENVEYPDPDKFHKIKCETRDLNGEDVQAKFYLDNRLVTTQVGAGYLGKPMYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZ65</accession>
    <name>E3QZ65_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_11297</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697411">
        <property type="protein sequence ID" value="EFQ36153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100173.1">
        <property type="nucleotide sequence ID" value="XM_008101982.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZ65"/>
    <dbReference type="STRING" id="645133.E3QZ65"/>
    <dbReference type="GeneID" id="24416662"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11297"/>
    <dbReference type="eggNOG" id="KOG2614">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_19_3_1"/>
    <dbReference type="OrthoDB" id="16820at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000115">
        <property type="entry name" value="Salicylate hydroxylase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF242">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="23"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ36153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="477" mass="53612" checksum="4F5D47EF8C67FFBF" modified="2011-01-11" version="1">MQTRDFRGYVIQERIQRDATSKLHVIIVGAGLGGLGAAISTLLAGHEVTVLEAASNIGEVGAGIQVLPNAARILFSWGLEEKLEKFATKPQKCNFIGWKGNFLSDMDYHAYTTAAGGFPFWDFHRSDLHRCLLERAVELGAKLETGAKVDTFTVSPDNATATVFLADGRRMSGDLVVGADGINSKLREEFLCRPDPPQLTGDLAYRLLLNTSDMLKDPELRNFVENPQVNYWVGPDKHAVNYVLKGGKLFNMVLLVPDDMPIDCGNTLQGDIEEMRGHFEGWDPRISKMLQMCDEVLKWRLCIRPGLEPTWSHPSGAFTMLGDAVHATLPYLASGAGMALEDGGVLGLCLARLTDKSQSSKQKALKIYEECRRERTERVVRRGTYNQWTYHLHDGKEQVERDEKFKRFGEMDERWLREDSPVLPESQETGDDPFPWRYHGVGRWLLTYDMWKDIESKCPSTPPAFSLQDCQVPRASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZH2</accession>
    <name>E3QZH2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mitochondrial transcription factor 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_11405</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Mitochondrial transcription factor that confers selective promoter recognition on the core subunit of the yeast mitochondrial RNA polymerase. Interacts with DNA in a non-specific manner.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697416">
        <property type="protein sequence ID" value="EFQ36260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100280.1">
        <property type="nucleotide sequence ID" value="XM_008102089.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZH2"/>
    <dbReference type="GeneID" id="24416769"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11405"/>
    <dbReference type="eggNOG" id="ENOG502QY7G">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014537_1_0_1"/>
    <dbReference type="OrthoDB" id="16079at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034245">
        <property type="term" value="C:mitochondrial DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034246">
        <property type="term" value="F:mitochondrial transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006391">
        <property type="term" value="P:transcription initiation at mitochondrial promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.100">
        <property type="entry name" value="Ribosomal RNA adenine dimethylase-like, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023165">
        <property type="entry name" value="rRNA_Ade_diMease-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="DIMETHYLADENOSINE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727:SF17">
        <property type="entry name" value="DIMETHYLADENOSINE TRANSFERASE 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="611"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="622"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ36260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="633" mass="71451" checksum="073BCFD6991B1632" modified="2011-01-11" version="1">MIALRHAWEKPLLTHRMLTRAAATGAAVRLSKDILQTKTPTAKNLAKLGLWTTQADRVKEIKAAKKAPKGKAKEHVKKPRGDKARVNVVSEELCDDIIKYIGPTLERHRGCDLVDINPGAGVWSTKLHDFLQPRSHILMEPDEDLYRPFLEPLIQRPDTQLLPQSGILWKELNEALGHIKNQTPRPRDPATVPERNDTLLLTANLAFYPKKRYRTFDSVAQLVIYQLISSIRNGNLFQKYGLVRMLIWTGPDEQYTFLAKTVQGRKKSVLDAEFACEWLAEVASRDMMLDIKPEARFVRDRWIDIDSARDTMARMKASGIVIPEGRKHSMTKRLQEEAAAYDGPQAGVQVPYLHRPYFAEIEELKQASRDGPLDSKRRSRLQFLSHQAERLEEYLVKHRDLLEEMKVTARLRQSIDNGDRDGDKAAAEAEFVARDRALNEKVGALGKNLSIDFRAIRDNLHVFRQNSSALLWDRRPYEPLAVRADEFFPNAECTLLDIQPKAMHPLLRQTGPGTSRAGDAFEMLQRSMFSASNDPISRSVERIWPGAAEGVLPNCPSLRDPAQGGLPGTGHGEICARVLNEKQWTELLEAFMAWPFRPSYQQLIGRLADDFEPAGDDDHNGAGSSLSAESVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZU7</accession>
    <name>E3QZU7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GrpB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_11530</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697421">
        <property type="protein sequence ID" value="EFQ36385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100405.1">
        <property type="nucleotide sequence ID" value="XM_008102214.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZU7"/>
    <dbReference type="GeneID" id="24416894"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11530"/>
    <dbReference type="eggNOG" id="ENOG502SEGQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086407_1_0_1"/>
    <dbReference type="OrthoDB" id="630895at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007344">
        <property type="entry name" value="GrpB/CoaE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34822">
        <property type="entry name" value="GRPB DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G01530)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34822:SF1">
        <property type="entry name" value="GRPB FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04229">
        <property type="entry name" value="GrpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ36385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="204" mass="23445" checksum="2F5D5881E571D0C1" modified="2011-01-11" version="1">MPCSVEDILKNYEYDPSIVQRIATRKVNLPLAIEPPNPEWPAQFEKIKSLIDGALGPVALSVNHVGSTSVPRLPAKAVIDIDLVVADPTDKDAYAPALERVGFQFILREPEWHEHRFFAMYEPYHCNLHVFKEGTAELVRHIIMKEWLIANDDDRELYARTKMEAAEMSNSLGEEVMDYNLRKENVIREILQRAFKAKGYLDHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZZ6</accession>
    <name>E3QZZ6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_11579</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697424">
        <property type="protein sequence ID" value="EFQ36434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100454.1">
        <property type="nucleotide sequence ID" value="XM_008102263.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZZ6"/>
    <dbReference type="GeneID" id="24416943"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11579"/>
    <dbReference type="HOGENOM" id="CLU_2922503_0_0_1"/>
    <dbReference type="OrthoDB" id="5238343at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ36434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="61" mass="6501" checksum="207372EE7952513D" modified="2011-01-11" version="1">MKAGGHGCDPLWGFIARSRAGHPGYCCRETPDGTVETEDGETLEEASVFFTGPAAESKEQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0C4</accession>
    <name>E3R0C4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Adenine DNA glycosylase</fullName>
            <ecNumber evidence="4">3.2.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">GLRG_11721</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolyzes free adenine bases from 7,8-dihydro-8-oxoguanine:adenine mismatched double-stranded DNA, leaving an apurinic site.</text>
            <dbReference type="EC" id="3.2.2.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Nth/MutY family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.31" evidence="4"/>
    <dbReference type="EMBL" id="GG697439">
        <property type="protein sequence ID" value="EFQ36562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100582.1">
        <property type="nucleotide sequence ID" value="XM_008102391.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0C4"/>
    <dbReference type="STRING" id="645133.E3R0C4"/>
    <dbReference type="GeneID" id="24417085"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11721"/>
    <dbReference type="eggNOG" id="KOG2457">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012862_0_0_1"/>
    <dbReference type="OrthoDB" id="10248838at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034039">
        <property type="term" value="F:8-oxo-7,8-dihydroguanine DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035485">
        <property type="term" value="F:adenine/guanine mispair binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032357">
        <property type="term" value="F:oxidized purine DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000701">
        <property type="term" value="F:purine-specific mismatch base pair DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006285">
        <property type="term" value="P:base-excision repair, AP site formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03431">
        <property type="entry name" value="NUDIX_DNA_Glycosylase_C-MutY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.340.30:FF:000002">
        <property type="entry name" value="Adenine DNA glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="entry name" value="Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003651">
        <property type="entry name" value="Endonuclease3_FeS-loop_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000445">
        <property type="entry name" value="HhH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044298">
        <property type="entry name" value="MIG/MutY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029119">
        <property type="entry name" value="MutY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42944">
        <property type="entry name" value="ADENINE DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42944:SF1">
        <property type="entry name" value="ADENINE DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00633">
        <property type="entry name" value="HHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14815">
        <property type="entry name" value="NUDIX_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00525">
        <property type="entry name" value="FES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HhH-GPD" evidence="15">
        <location>
            <begin position="178"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="319"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="417"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="66"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="84"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="319"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="338"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="417"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="427"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="460"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EFQ36562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="665" mass="71698" checksum="2C385C21987A568D" modified="2011-01-11" version="1">MIQRGIVRRQSSLAAAKRISAQADDEPDSEPVKAISRTRKAAVKPPLASPRKDASEADFTPPVDDDGVKDISEPPPKRRKVERTRKSDTEKLHASLFGPSGQAATTTTTPDPCPPPSRTHAANYHRPLLLDGRPGRGGRDALLAWPGSTPRRSHPDGAAGLRAALERRAYEVWISEIMLQQTRVAVVIDYWNRWMARWPTIRDLAAAAPEDVLAAWRGLGYYSRATRIHEAAKLVVADPGWAGLMPADTAELEAKVPGVGRYTAGAIAAIVFGRAAPMVDGNVLRVLSRQLGVFGNAKTDKAVIDLLWAAADALAKAVARDDPEDARDRISDEDEEAPPPPPPPPTSDRPGRWGQALMELGSTVCTPKPNCGACPVTSTCRAYAEGLLVAAKPTRAAKVEDIEDLCSICEPFEEEEAAAAAAEDEAALSREDSDAKAPKAVKGGKEAGKGTRSRPVAKQATLSAFFSSSSKTAKKEQEPASPGPRAADARTLEIIAEHARKFPLKVVKKAVREEEALVCAVRRRSDGRFLVHRRPDKGLLAGMWELPSHTLTPTAASNTASSRKRDAQGYVSGLLLGGGEKQQKARAKDGPRARHVGDLGSVPWLFSHIKLTMHVHLFEVEGGEGGCVSSSHARHRWATAEEVDEESMGTGMRKCWALVKERVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0E4</accession>
    <name>E3R0E4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Non-repetitive/WGA-negative nucleoporin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">GLRG_11715</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Nucleoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the non-repetitive/WGA-negative nucleoporin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697440">
        <property type="protein sequence ID" value="EFQ36582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100602.1">
        <property type="nucleotide sequence ID" value="XM_008102411.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3R0E4"/>
    <dbReference type="GeneID" id="24417079"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11715"/>
    <dbReference type="eggNOG" id="KOG1900">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000429_0_1_1"/>
    <dbReference type="OrthoDB" id="338970at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044611">
        <property type="term" value="C:nuclear pore inner ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051292">
        <property type="term" value="P:nuclear pore complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036228">
        <property type="term" value="P:protein localization to nuclear inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006405">
        <property type="term" value="P:RNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000972">
        <property type="term" value="P:transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.440:FF:000001">
        <property type="entry name" value="Nuclear pore complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.450:FF:000002">
        <property type="entry name" value="Putative non-repetitive nucleoporin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1880">
        <property type="entry name" value="Nucleoporin, helical C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.440">
        <property type="entry name" value="Nucleoporin, helical domain, central subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.450">
        <property type="entry name" value="Nucleoporin, helical domain, N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007187">
        <property type="entry name" value="Nucleoporin_Nup133/Nup155_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014908">
        <property type="entry name" value="Nucleoporin_Nup133/Nup155_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004870">
        <property type="entry name" value="Nucleoporin_Nup155"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042533">
        <property type="entry name" value="Nucleoporin_Nup155_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042537">
        <property type="entry name" value="Nucleoporin_Nup155_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042538">
        <property type="entry name" value="Nucleoporin_Nup155_C_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10350">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10350:SF6">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03177">
        <property type="entry name" value="Nucleoporin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08801">
        <property type="entry name" value="Nucleoporin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="9" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Nucleoporin Nup133/Nup155-like N-terminal" evidence="14">
        <location>
            <begin position="136"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoporin Nup133/Nup155-like C-terminal" evidence="13">
        <location>
            <begin position="680"/>
            <end position="1338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="77"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EFQ36582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1405" mass="155245" checksum="33506A5124AE673E" modified="2011-01-11" version="1">MSYPQLTPARPVPGAFFNTPAASRFANENDPARRRLFVDAETGQGSSATASSSALVGPPSSLATATISSMSTGGGMVSTSSSQPPQQNLPPVTRAAQAVNQFLQSDENYPELDSYCRPGASSEYDFNTLDSPWAPFHKTQMYPIPNQVFSHYNTGQLQTLMGLFAEINHAWVVIDNSLFLWDYTHPDPELIGFEDQPHTIHAVALVAPKPGIFVNTITHILVVATSSEMILLGLSAEPTPSGTKTVSLYSTKLNLPLRGTDVRVIAGTADGRIFFGGSNDTDIHELYYQQEEKWFSSRCGKINHTNPGWSSVVTLQSSFWAHKSPEGLQSIVIDDSRKLVYTLSTRSTIRTYHMDGPDKLTKVIEKERNACLRDITHMITQSPLLNDRTTFVSISAIPSREASKLHLMALTNTGCRLFLSATSSASYMIGGISSNTPPQSMQVQFIKFPPSDKPGRSGTNSNGDAVIDLGSRALELSRLGARFAPGYFLDFVVKENDPNIDLLFVSAPETGRIKANSSSSTLKYYEHGNWIDIGSRAEDVGLVTKPFAAAKQPIGFGNELAVQFDEPSTEFAVLTNTGVHIIRRRRLVDTFAAAIRGAVGDEGLEMETRKFISRYGRVETISCALAVACGYGGDARPGATRAIDQATEDRARAVFVDFGGQPTITEADGTPLNTTLVRLSPRHDALCVYLTRLIRTLWKNHVVAAAPNTAGGIAIHSMVPISRLHSIQEQLERLRRFLDANKSFIQGLSGPSDLQRVASKQEEVALQAEHQALHALQKLMESISEGISFVLMLFDERVSDIFTRLDATAQQDLRNLTYESLFSQAPGKDLAKLLVKSIVNRNIESGSNVETVADALRRRCGSFCSPDDVVIFKAQEQLKRASEQPLNSNPSRTLLHESLRLFERVAGALSFSNLHNAVSQYIDLKYYAGAIQLCLTVAREKDRGNSALSWVHDGKPGNDPRANAFAERRKCYELIHEALQHLDAASSREPETIDGRLTLIGTKRLEAYSVVNDSDDEVFHFDLYEWYIEQGWTDRILAIESPHVITYLQSLARTNVEHADLLCRFYTQRERYFEAAQVQNDLAQSDFAIGIKDRITLLSKAKANANVATAGVGRQQQQVLAHEVSELLDIANIQDDLLERLKADSRIAPERKAEIEEALDGQVVSLSDLFNQYADQANYYDLCLLIYHSADYRNPTTIAQTWISLIEQIHEEAVERMEEAGPGIPVLPSPYESVSVKVQNIAHRTSLDSFIFPVPVLLPEICRYAVEHHQDAEIGADPTWPVQLFLSLGVSHDMATRVLESVFDTQDYGFSGNNRNRIIELIVFAVDVWQREVKRRGGVSMKGDGAIGAWVKDLLSRCENSLPPAGHGSNPGGMDLAEIRRRLRTVRREVEGLVDRGPSGSLRFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0H4</accession>
    <name>E3R0H4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11757</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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    </dbReference>
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    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11757"/>
    <dbReference type="HOGENOM" id="CLU_1758667_0_0_1"/>
    <dbReference type="OrthoDB" id="4845518at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="148" mass="16785" checksum="9CCE391A6715451C" modified="2011-01-11" version="1">MRQRWPDLYPPVLQEPIGPMGLLKRYFKGLITYHQGFQVFPGVTDFFQMICTIPCVVTDVVRCFTSDSNPIAIDTKTAGKTEPSSQPDSHATSRTVILRQQFNTPDRISVTISVIAVFEKGALQSRTLSYTQPYFPYAKERPRRHGGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
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    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_11787</name>
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    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EFQ36642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008102471.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0K4"/>
    <dbReference type="GeneID" id="24417151"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11787"/>
    <dbReference type="eggNOG" id="ENOG502T5Q0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_180930_0_0_1"/>
    <dbReference type="OrthoDB" id="3660930at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003181127" evidence="2">
        <location>
            <begin position="22"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ36642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="85" mass="8568" checksum="64B9C7370528C898" modified="2011-01-11" version="1">MKTSVRNLLLLSYAATAYVAAAPGSGDARAAAICGDLGVLSIEDGQLPEGVSRADLRMCAGHPNGRTRVLDPEQGASLAPMGGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0N9</accession>
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    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11823</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EFQ36677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008102506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0N9"/>
    <dbReference type="GeneID" id="24417186"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11823"/>
    <dbReference type="HOGENOM" id="CLU_1170568_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="184"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="237" mass="19578" checksum="EBFDAD15C4E92146" modified="2011-01-11" version="1">MPGAGGFGGGGFGGFGGGGFGGGGEYGGGGGYGGGGGYGSGGESGSGGEYGSGGESGSGGESGSGGESGSGGESGSGGASGSGGESGSGGESGSGGASGSGGASGSGGESGSGGASGSGGASGSGGESGSGGASGSGGASGSGGASGSGSESGSGSESGSSTQGGSTAPSDSTTPEGPTASGQPTVPGKPTTPGAPTTPGAPTTPDGPADSTDSSDPDGPTPSAAPPKPSKPKPSGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q1X1</accession>
    <name>E3Q1X1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">2-dehydropantoate 2-reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_00216</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
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        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ketopantoate reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089092.1">
        <property type="nucleotide sequence ID" value="XM_008090901.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q1X1"/>
    <dbReference type="STRING" id="645133.E3Q1X1"/>
    <dbReference type="GeneID" id="24405581"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00216"/>
    <dbReference type="eggNOG" id="ENOG502QPT5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031468_9_0_1"/>
    <dbReference type="OrthoDB" id="73846at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008677">
        <property type="term" value="F:2-dehydropantoate 2-reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050838">
        <property type="entry name" value="Ketopantoate_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013752">
        <property type="entry name" value="KPA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013332">
        <property type="entry name" value="KPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43765:SF2">
        <property type="entry name" value="2-DEHYDROPANTOATE 2-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43765">
        <property type="entry name" value="2-DEHYDROPANTOATE 2-REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02558">
        <property type="entry name" value="ApbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08546">
        <property type="entry name" value="ApbA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketopantoate reductase N-terminal" evidence="4">
        <location>
            <begin position="60"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="Ketopantoate reductase C-terminal" evidence="5">
        <location>
            <begin position="268"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ25072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="449" mass="50501" checksum="C0F763487A0FEDA0" modified="2011-01-11" version="1">MPPAWLQSVLNATVKKEAPRLYVWNLSNLEGQAQPFSSPASSRPDELTPYRHEDNLYRRVYILGVGNLGTLFASSLASLPEPPPITLVVHRKDLLLSWREQPGIEMTRQGSIYKHLDFDVELWSEEPPSTGLKREVTEGQQIHNLIVATKASQALPAVDRIRRYLNENSTIVFAQNGMCKLWPPHGKTYSKSRYLGESHPNFLACVTTHGVTSLGRFKSFHASEANLKIGPILLNEFPENDSYLSDVLCRAPTLHGEKVTQDELWILQLEKLVVNSIINPLTAILRCKNGDLFNEKEGVLAELINALLLEASKVLQALIKDRSTDAIIRPASREATSTTKVELDHEDIRRRRDLLNRFSQPQLREMLYSVGNKVKDNTSSMLQDVRAGKQTEIEEFNGWLVETATCLNDNLDVTHHRILIDLVHDGNVLPKESLVNYFPSCKGSKSAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q284</accession>
    <name>E3Q284_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00329</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008091014.1"/>
    </dbReference>
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    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00329"/>
    <dbReference type="eggNOG" id="ENOG502RPBW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1875273_0_0_1"/>
    <dbReference type="OrthoDB" id="10430044at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="136" mass="15244" checksum="060B1AC1AE7E742E" modified="2011-01-11" version="1">MDQSTKPEVEPKDDSVTDPIQAAKRTCDVLSAGIKSMKIPKAIDKAKNLADYIQILEFSDMINDMRIRVNVSRSSIQDVRNSTLDEQSIKLLGEVDQGFDTLLTRIEGLRECVDQWMETMKGGWTPLKKDKTSPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2B8</accession>
    <name>E3Q2B8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_00363</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089239.1">
        <property type="nucleotide sequence ID" value="XM_008091048.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2B8"/>
    <dbReference type="STRING" id="645133.E3Q2B8"/>
    <dbReference type="GeneID" id="24405728"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00363"/>
    <dbReference type="eggNOG" id="ENOG502SI5H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045564_0_0_1"/>
    <dbReference type="OrthoDB" id="5325862at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ25219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="288" mass="31031" checksum="A8209E91D460759D" modified="2011-01-11" version="1">MSFIIDEKPQTHLEVDPYDHDVMSGDSDSEVPPAYDDAFSKAPSTVQLQIHAVGYDYGQALTGNTLENIAVDRVETGELAYTSVRLSRSSNSCALVRGHDTSRSLISTIYRWGPGRPPRMRVFAGPAGVSVDDAIHNDHLPCELVNVKSRNVFSRTQRFATSFGTFEWRYADRAERKQPENNADSLLVCERTDGGGTGSSGGKAGKRGVQVAQLVRNEAMRTPGTTRWMGGNGGRLALDLSGWADAAAADGKGATAAQGVEAFLVASCICMLKREADRFKDNAIASVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2D3</accession>
    <name>E3Q2D3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glutamine amidotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00378</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089254.1">
        <property type="nucleotide sequence ID" value="XM_008091063.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2D3"/>
    <dbReference type="STRING" id="645133.E3Q2D3"/>
    <dbReference type="GeneID" id="24405743"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00378"/>
    <dbReference type="eggNOG" id="KOG3179">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054974_0_0_1"/>
    <dbReference type="OrthoDB" id="92161at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044992">
        <property type="entry name" value="ChyE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42695">
        <property type="entry name" value="GLUTAMINE AMIDOTRANSFERASE YLR126C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42695:SF5">
        <property type="entry name" value="GLUTAMINE AMIDOTRANSFERASE YLR126C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase" evidence="1">
        <location>
            <begin position="59"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="247" mass="27997" checksum="F5AD52C3D4E961AA" modified="2011-01-11" version="1">MGSLPQSNPLRVAIVKAYEIDEPKHRGMLQSFRDNILQQVPDAVINAYRPMNQDGHLPNPANYDLVIITGGLSNLCQATFEPWVNTTLEWIRQVVSQQHITKTKLLGICWGHQAIATALSGSIGSFEHPRVGVQHLTLNDNGKEMFGRDTLKLTKFHRRFVQQVPDGFKPMAPDNEILFSDSGLVLSLQGHPEIYGELSRQLFETNVPYYRATLPTEEDLQRYYSEMSSSEEDAKLIFRKIADWAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2I6</accession>
    <name>E3Q2I6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Mitochondrial import receptor subunit tom-22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_00431</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tom22 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089307.1">
        <property type="nucleotide sequence ID" value="XM_008091116.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2I6"/>
    <dbReference type="STRING" id="645133.E3Q2I6"/>
    <dbReference type="GeneID" id="24405796"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00431"/>
    <dbReference type="eggNOG" id="KOG4111">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094333_1_0_1"/>
    <dbReference type="OrthoDB" id="10016939at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22884">
        <property type="entry name" value="TOM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005683">
        <property type="entry name" value="Tom22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12504">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12504:SF0">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM22 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04281">
        <property type="entry name" value="Tom22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="129"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ25287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="156" mass="17203" checksum="529E19828DFBCD6A" modified="2011-01-11" version="1">MVQLTEVEDEHFQSGQNGPIEDDADYTDTDSEISADSDYDPRDESFAERLYALKDIVPPTTRGWISNKVDLGVSAVQNTWYYGSRTVWVVCATALMIGVPLATCWAEDQQIEGMEREYRMREMGGDALLTAGESKDGSTADQVGLALDRAEAKPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2V9</accession>
    <name>E3Q2V9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Enhancer of mRNA-decapping protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_00082</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">P-body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EDC3 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ24938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008088958.1">
        <property type="nucleotide sequence ID" value="XM_008090767.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2V9"/>
    <dbReference type="STRING" id="645133.E3Q2V9"/>
    <dbReference type="GeneID" id="24405447"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00082"/>
    <dbReference type="eggNOG" id="KOG2585">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024328_0_0_1"/>
    <dbReference type="OrthoDB" id="10030313at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031087">
        <property type="term" value="P:deadenylation-independent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033962">
        <property type="term" value="P:P-body assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10260:FF:000007">
        <property type="entry name" value="YjeF N-terminal domain-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10260">
        <property type="entry name" value="YjeF N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025762">
        <property type="entry name" value="DFDF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019050">
        <property type="entry name" value="FDF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004443">
        <property type="entry name" value="YjeF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036652">
        <property type="entry name" value="YjeF_N_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13612">
        <property type="entry name" value="ENHANCER OF MRNA-DECAPPING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13612:SF0">
        <property type="entry name" value="ENHANCER OF MRNA-DECAPPING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09532">
        <property type="entry name" value="FDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03853">
        <property type="entry name" value="YjeF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01199">
        <property type="entry name" value="FDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64153">
        <property type="entry name" value="YjeF N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51512">
        <property type="entry name" value="DFDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51385">
        <property type="entry name" value="YJEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DFDF" evidence="7">
        <location>
            <begin position="267"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="YjeF N-terminal" evidence="6">
        <location>
            <begin position="429"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="164"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="309"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="357"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="195"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="238"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="361"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="379"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ24938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="718" mass="78487" checksum="93C67ADB3E9B7762" modified="2011-01-11" version="1">MEFIGLQMMVTLRQPPGTMLKGTVSAIQAGNSLTLSNVFTLGTNHWMPRVVIDAANILELSEFKEEAASNTFTAPGLGPVPAPVITQPAQPAFTDPAILSMGNRPGSDMRSGSEKQTLPEVIPQTTAAETKDPRPGQPGVLSAVHLMGGSRDDVVSLSETLQELDVEEHTPTARQYAAESSGVPQDAHEVQGQPQKKKNRRREKQRAPRNSTADETIPEITPMRGNAATRGKGWRQTPMLQSSPSFQPFNSLKRGIKGKKDLPENGWASEDVTEEMAEFDFENNLAKFDKRTIFDQMRKEDLIDEADRLVSHNRRPKPGTAGGKNFHYSENVLEMPSVSSNAHQDFWNSEADDAANGVDRLSGRDVRSAQSSRRADSKSGATRRSQSRKASAQLNSQPLNRVNSNHITQAGFYLVPSNRRLETVSALQMLNLENIAANEIGLTEDMMAENAGRGIAEVTLRALEDPAIQVRFGTGGANAQNNSLAASATIVILAGNNKSGIRAISAARHLRNKGLNILVCVVGIERERDLLEDMRQQIRIFRNFGGRVHNKLELFEQLRKTASTPATSVSLIIDALLGLAISFEELRTGDQATVYELIEWANRNEAFVLAVDVPTGIDPSTGKVSIIDGGRLYVKPRYVVAMGAPKKGLLEAMAPVSDSDPTGAETAAAEEEDWKLFIADMGLGATVWKKAGTKIRRGIDFDDKWVLQMRYQPPHSQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3C3</accession>
    <name>E3Q3C3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 9">Uracil-DNA glycosylase</fullName>
            <shortName evidence="7">UDG</shortName>
            <ecNumber evidence="7 9">3.2.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">UNG1</name>
        <name evidence="12" type="ORF">GLRG_00669</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 9">Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 9">
            <text>Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.</text>
            <dbReference type="EC" id="3.2.2.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 9">Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.27" evidence="7 9"/>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089545.1">
        <property type="nucleotide sequence ID" value="XM_008091354.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3C3"/>
    <dbReference type="STRING" id="645133.E3Q3C3"/>
    <dbReference type="GeneID" id="24406034"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00669"/>
    <dbReference type="eggNOG" id="KOG2994">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032162_2_0_1"/>
    <dbReference type="OrthoDB" id="10031947at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004844">
        <property type="term" value="F:uracil DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097510">
        <property type="term" value="P:base-excision repair, AP site formation via deaminated base removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10027">
        <property type="entry name" value="UDG-F1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.470.10:FF:000007">
        <property type="entry name" value="Uracil-DNA glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="entry name" value="Uracil-DNA glycosylase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00148">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002043">
        <property type="entry name" value="UDG_fam1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018085">
        <property type="entry name" value="Ura-DNA_Glyclase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003588">
        <property type="entry name" value="PRK05254.1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003589">
        <property type="entry name" value="PRK05254.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003592">
        <property type="entry name" value="PRK05254.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00628">
        <property type="entry name" value="ung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11264">
        <property type="entry name" value="URACIL-DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11264:SF0">
        <property type="entry name" value="URACIL-DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00987">
        <property type="entry name" value="UreE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="Uracil-DNA glycosylase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00130">
        <property type="entry name" value="U_DNA_GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7 9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 7 9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uracil-DNA glycosylase-like" evidence="11">
        <location>
            <begin position="143"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="330"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="330"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7 8">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ25525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="363" mass="40091" checksum="ACA3740422B19169" modified="2011-01-11" version="1">MSTLKRKAGTLSATDNKKPKQDGSIMSFFGAPKPVAKASGAGAPEASPADKFDKAKWIAGLTAEQKELLQLEIDTLHESWLALLKDEVTSKEFLDLKRFLNRESDAGKKWFPPKEDVYSWYVSDPSAAHGFGTTSPNQERRSRHCPFNTVKVVILGQDPYHNHNQAHGLAFSVRPPTPAPPSLKNMYIALKKDYPTFSPPPNKGGLLTPWADRGVLLLNTCLTVRAHEANSHANRGWERFTQKVIDLVASKRTRGVVFMAWGTPAGKRVVKVDTKKHLVLKSVHPSPLSASRGFFDCGHFKKANEWLVTRYGAGAEIDWDLSAAKKVEIDKDGEVEKVETEEKEPKTSPKGPAEGDSPKDDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3P8</accession>
    <name>E3Q3P8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NAD dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00794</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089670.1">
        <property type="nucleotide sequence ID" value="XM_008091479.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3P8"/>
    <dbReference type="STRING" id="645133.E3Q3P8"/>
    <dbReference type="GeneID" id="24406159"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00794"/>
    <dbReference type="eggNOG" id="ENOG502QSRH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030125_1_0_1"/>
    <dbReference type="OrthoDB" id="1731983at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="FAR_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055222">
        <property type="entry name" value="PRISE-like_Rossmann-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32487">
        <property type="entry name" value="3-OXO-DELTA(4,5)-STEROID 5-BETA-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32487:SF0">
        <property type="entry name" value="3-OXO-DELTA(4,5)-STEROID 5-BETA-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22917">
        <property type="entry name" value="PRISE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioester reductase (TE)" evidence="1">
        <location>
            <begin position="6"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="PRISE-like Rossmann-fold" evidence="2">
        <location>
            <begin position="61"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ25650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="292" mass="33455" checksum="7D87CD73DFB1B46C" modified="2011-01-11" version="1">MSSAIVTGATGILGREIVDRLAQNPEQWKTIYAISRSQRDQYPPNIKHGFIAKDLQGVEAEYVFFAAYLQKDSEKENWDANGDMLRNFLAALEKTGAADKIKRILLITGAKQYGVHRCVPSNPMEDSEPWHREDPPLPPIFYNLQQDILRAFCERHPNVSWTVKYPNDVIGFAKDNYMRLATTLGIYAAITRELGRDLEFPGSETFYTKFDCFTSARLHAEFCEGLERDAFDKATWSYLGFVLGRNFDLVISMSKAREMGWTGWADTWQSLQDFFGQLETEKILPRAYGYAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3V0</accession>
    <name>E3Q3V0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_00846</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089722.1">
        <property type="nucleotide sequence ID" value="XM_008091531.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3V0"/>
    <dbReference type="STRING" id="645133.E3Q3V0"/>
    <dbReference type="GeneID" id="24406211"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00846"/>
    <dbReference type="eggNOG" id="ENOG502QS8H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_49_0_1"/>
    <dbReference type="OrthoDB" id="294702at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ25702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="212" mass="23773" checksum="1DE0396B2F1A87BB" modified="2011-01-11" version="1">MFIAHASAEQGVSGGGPYALACAASMPDEKLKCVSIVCGIGPPDIGMTGAGWFHWVGFTYGWRYAPRLAGWFFHRQGRFHLSDEKRLALQLEEAEKNKATFPKQELGIWADSEIVGRMVKTSRQYYAQGIDGVSHDGHLVGTEFGFDIEDIRSDLPVQLWYGKDDTFVPLNHGKQIAKRLGNSAHLRVEDDTHASIFFKWRKEILADLVRCM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4R6</accession>
    <name>E3Q4R6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">WD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_01225</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat TAF5 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ26081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090101.1">
        <property type="nucleotide sequence ID" value="XM_008091910.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4R6"/>
    <dbReference type="STRING" id="645133.E3Q4R6"/>
    <dbReference type="GeneID" id="24406590"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01225"/>
    <dbReference type="eggNOG" id="KOG0263">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005884_0_2_1"/>
    <dbReference type="OrthoDB" id="10266330at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08044">
        <property type="entry name" value="TAF5_NTD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.500">
        <property type="entry name" value="TFIID subunit TAF5, NTD2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007582">
        <property type="entry name" value="TFIID_NTD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037264">
        <property type="entry name" value="TFIID_NTD2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879:SF1">
        <property type="entry name" value="CANNONBALL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08513">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04494">
        <property type="entry name" value="TFIID_NTD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00667">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160897">
        <property type="entry name" value="Taf5 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3 8" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="TFIID subunit TAF5 NTD2" evidence="10">
        <location>
            <begin position="124"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="410"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="502"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="529"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="571"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="615"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="665"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="354"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="724"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="8"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="66"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="727"/>
            <end position="739"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ26081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="790" mass="87012" checksum="9525AA7E1452A278" modified="2011-01-11" version="1">MSGNPGQPGASSTTPGAGASGSFSQQQQQQQQQQQPATTTSTTPGAGGAAPAPAPVTQTPIPPPTTATAPAPATAPMSNQNLNQIVTDYLLKRGYTRTETIFRQESSHLGPDGRPIHNKVDDLGPRKYLKAFNLLREWVENNLDIYKFELNKLLWPVFVYSWLELVTQNYSEEAKSLLNKLKPYFENVHSDDLKTFSTITLALHAKENPTTKLYRENKYRIPLNQHITGNLFHFLERERDNGGSVILYILSTFCHLDSTARGPIEPFSFEAIYRRSQNLEIDEVDLQEGIPGVFTGISNRDLLDKTVPLKLGPLPMEEDLRDDVRAELQDEDALNPPPEGRSTLVDEFDRKIKREESADGPNRSELPLPPSRARDVVMEMQKVRENRDRFKIEGRTGGVGVAVSACMFTFHNTLGSVSCMDFSKDHEMVAIGTTDSYIRVWHLEGKPLKSKRPDEKDFKFNNRKLIGHSAQVFSVSFSDSIAKLDRAPFGEEGKGESPIETSSKLLLSCSADGTVRIWSLDIWACVCVYKGHDGPVMRAEWGPHGHYFLTGGWDKTARIWMQDHASAQRILVGHDSSISAVAWHPNGTYVFSASDETDKSIRMWSVITGQCVRVFTGHTDYISAIECAPNGRILATADNSGNIFFWDIQKGARIKRSRGHGKGGIWSLSFSVESNVLVSGGQDGTVRVWDVDLPAEGHKVVQQQQGTAPTQEGGDTIVAATGQTDRASASGQGATGSSSNAPSGSKKKGKEVMITPDQISAFPTKKTPVMKVQFTRMNLIVAGGCYDPDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4R8</accession>
    <name>E3Q4R8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosomal protein bL31m N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_01227</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ26083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090103.1">
        <property type="nucleotide sequence ID" value="XM_008091912.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4R8"/>
    <dbReference type="STRING" id="645133.E3Q4R8"/>
    <dbReference type="GeneID" id="24406592"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01227"/>
    <dbReference type="eggNOG" id="ENOG502RZ6E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109501_0_1_1"/>
    <dbReference type="OrthoDB" id="5587740at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034600">
        <property type="entry name" value="Ribosomal_bL31m"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048874">
        <property type="entry name" value="Ribosomal_bL31m_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28174">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN L36, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28174:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL31M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21492">
        <property type="entry name" value="bL31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal protein bL31m N-terminal" evidence="2">
        <location>
            <begin position="60"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ26083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="196" mass="21187" checksum="7C816DC95779A96A" modified="2011-01-11" version="1">MGKLPTHLPRPTSLLCHRPRTSISITSSCSSSPLPYNASTPVQRTTLIQTRAATFVPRARRPYTFTQLIQLSDGSAYTVRTTSPAALVRSAKDTRNHALWLPSEKTLQNVELDEAGKLAAFRERFGRGFDIAAGPAAQEETAAAAADAAEENKAPVTPAQAKDDVFDMGDLISGYAALEPKKVFSDSKKGSRKKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4S4</accession>
    <name>E3Q4S4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Proteasome assembly chaperone 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_01233</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ26089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090109.1">
        <property type="nucleotide sequence ID" value="XM_008091918.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4S4"/>
    <dbReference type="GeneID" id="24406598"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01233"/>
    <dbReference type="eggNOG" id="ENOG502SAIH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108992_1_0_1"/>
    <dbReference type="OrthoDB" id="5407417at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043248">
        <property type="term" value="P:proteasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032157">
        <property type="entry name" value="PAC4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16093">
        <property type="entry name" value="PAC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ26089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="143" mass="15126" checksum="AAC87CC03626716E" modified="2011-01-11" version="1">MSSEGAVTQLSLPLPRSLDTRIHIHLTTKAKAVTLFLTSVTQDEQSGPAALGSFVYALPNRLEPAQPISTAIYSVESTLEFTTRMAKLLAKRTGMPVYVGCSINLGGSAMGLSVEEEMEAFRAIVDVVTGNLRSGQAAINGVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4W0</accession>
    <name>E3Q4W0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Carboxymuconolactone decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_01269</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ26125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090145.1">
        <property type="nucleotide sequence ID" value="XM_008091954.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4W0"/>
    <dbReference type="STRING" id="645133.E3Q4W0"/>
    <dbReference type="GeneID" id="24406634"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01269"/>
    <dbReference type="eggNOG" id="ENOG502RCP9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065389_3_0_1"/>
    <dbReference type="OrthoDB" id="5537330at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="entry name" value="AhpD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052999">
        <property type="entry name" value="PTS1_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28180">
        <property type="entry name" value="CONSERVED MITOCHONDRIAL PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28180:SF2">
        <property type="entry name" value="PEROXISOMAL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="AhpD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ26125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="261" mass="28728" checksum="145FAF1EFCB87B33" modified="2011-01-11" version="1">MPSVLPPIITPALLASIRSQPSLPRHVWYFVAATTLTILNRPDEIPQIYQHVMRHGVGSEDVKPGSDEQLAISRKLREALIKASAVGGLPKTINSLMELKKVTPEHLLDEPHGSDNCMTSSPTARYVDIHDTAPYKVLQRGQDFWNKIYGKISRRIMGQMDRCGTEDLGLTVRLIYGYILSNTKVLSPVETSYVLIAGLIPQDVNPQLKGHLRGALNGGASVEEVRAVRAIVIEICKAAGMRQLGDDMPAGWGWRSEVCCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q665</accession>
    <name>E3Q665_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_01457</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090333.1">
        <property type="nucleotide sequence ID" value="XM_008092142.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q665"/>
    <dbReference type="GeneID" id="24406822"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01457"/>
    <dbReference type="eggNOG" id="ENOG502RW66">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1722212_0_0_1"/>
    <dbReference type="OrthoDB" id="2873061at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="158" mass="17190" checksum="AC8BCDB178B0A3F0" modified="2011-01-11" version="1">MAKRDSLTVWLPKEMYGSVEPFADDRYIWSPMPFDESLPVEQTSFIDMGSTAGGATNPEPTSYEPLAPPPPAMFAGPADLATSDTDSERDFSLRKISQNLSRGRRRRPRGTQPAPQKRSGAGDGSRNSRGFAVHLGLNLDLEVTLKARILGGLEISAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q681</accession>
    <name>E3Q681_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">rRNA-processing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_01473</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Nucleus</location>
            <location evidence="2 8">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the CGR1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090349.1">
        <property type="nucleotide sequence ID" value="XM_008092158.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q681"/>
    <dbReference type="STRING" id="645133.E3Q681"/>
    <dbReference type="GeneID" id="24406838"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01473"/>
    <dbReference type="eggNOG" id="ENOG502S7VB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_125051_0_0_1"/>
    <dbReference type="OrthoDB" id="3942380at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005579">
        <property type="entry name" value="Cgr1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03879">
        <property type="entry name" value="Cgr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5 8" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="79"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="79"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ26329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="117" mass="13835" checksum="E5EA53727B497C3A" modified="2011-01-11" version="1">MSAAEPQTTTAVGNKSLGMRKNGKQWHETKRAFRPTSGLTSYEKRAKDRVAMAAMKAKEKEMKDEKEAERKQRIQTIKDRRAAKEEKERYEKMAEKMHKKRVERLKRKEKRNKLINS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6A8</accession>
    <name>E3Q6A8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cytoskeleton-associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_01500</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090376.1">
        <property type="nucleotide sequence ID" value="XM_008092185.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6A8"/>
    <dbReference type="STRING" id="645133.E3Q6A8"/>
    <dbReference type="GeneID" id="24406865"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01500"/>
    <dbReference type="eggNOG" id="ENOG502SE0J">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051207_0_0_1"/>
    <dbReference type="OrthoDB" id="5385189at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ26356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="337" mass="38681" checksum="79E82DF942D2C541" modified="2011-01-11" version="1">MTLMSFLRDERVILVGIGAATFGMITMMTQMLTYIRDDNEVKITPPKTQYITQETEDALGLETLDKLLCHPNFSIRDVAIKILCDRAVNDSDTVRYLLYGITRPDYDTRMTNLRALATLTGQTNDFAEGLSKLHTWRAYTALVRSLELSLADVEQTKLNDKYWDEYYLRDMAERFCLMFVLELITKYGADMLVKAKFVEKWLAKQYWGDDDAERQENFTYYMEHKNNRIVDIVTRIAHTTQGAKAILACNLISNKASPSVNPDPSLSGFSVVLHSTLCNVDGEDEGLQAVEQMPRTREHSAEEQRLRRQHREAMVFNDGTRPIGREDIIERSHDSPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6X5</accession>
    <name>E3Q6X5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dienelactone hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02433</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090633.1">
        <property type="nucleotide sequence ID" value="XM_008092442.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6X5"/>
    <dbReference type="STRING" id="645133.E3Q6X5"/>
    <dbReference type="GeneID" id="24407798"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02433"/>
    <dbReference type="eggNOG" id="KOG3043">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054590_0_0_1"/>
    <dbReference type="OrthoDB" id="2147163at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47668:SF1">
        <property type="entry name" value="DIENELACTONE HYDROLASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47668">
        <property type="entry name" value="DIENELACTONE HYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G01940)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="1">
        <location>
            <begin position="39"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="254" mass="28060" checksum="1AD596D3D4B8B37B" modified="2011-01-11" version="1">MSTMPAQHGHSVGCCNIPPVVSKGYEAKGTYEEIGGKKTYVTGPSDAKKAIVVIYDIFGYFPQTLQGADILATSGSEKYRVFMPDWFAGEPCPIEWFPPNTEEKQKNLGGFFQKFPPPKIAGLVPDYVKAVQSKFSSLESFGIIGYCWGGKVVSLVTSGEGNPFKVGAEIHPAMVEADDAKGIKIPLIMLASKDEPEEDVKKFESNLSVAKHVEIFKDQIHGWMAARSDLEDPRVKEEYTRGYKTVLEFFANNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q721</accession>
    <name>E3Q721_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02479</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090679.1">
        <property type="nucleotide sequence ID" value="XM_008092488.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q721"/>
    <dbReference type="GeneID" id="24407844"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02479"/>
    <dbReference type="eggNOG" id="ENOG502R9XK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2263551_0_0_1"/>
    <dbReference type="OrthoDB" id="4850174at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="102" mass="11168" checksum="7BF9EEE888341C24" modified="2011-01-11" version="1">MSSIESTQHLKAILRDQIDNKMSGAYYETAFIVPHLQTSVMPRRPRQPAPTSRPTVGAMASEATLVDKDGIPVMSKEKNDASGSMNGTSPKKSLLKRILKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q768</accession>
    <name>E3Q768_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Basic region leucine zipper</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_02526</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090726.1">
        <property type="nucleotide sequence ID" value="XM_008092535.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q768"/>
    <dbReference type="STRING" id="645133.E3Q768"/>
    <dbReference type="GeneID" id="24407891"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02526"/>
    <dbReference type="eggNOG" id="KOG1414">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_940103_0_0_1"/>
    <dbReference type="OrthoDB" id="295274at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14687">
        <property type="entry name" value="bZIP_ATF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051027">
        <property type="entry name" value="bZIP_transcription_factors"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19304">
        <property type="entry name" value="CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07716">
        <property type="entry name" value="bZIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="6">
        <location>
            <begin position="157"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="80"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ26706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="254" mass="27903" checksum="42E8724C8DD78D70" modified="2011-01-11" version="1">MSSVQWEAERQSQQSFEATGPTLHCTTASSVQPGYWPSFQQQQQYLQSPQSVFLSPPLQWPASTDNPLTTAPVPQPPPSKGRDRSKPEPEPGHRATATKKKVTTPARRPVDPRLVSMSQNHPKHAWVGVGGASESPPASSMSYEDKDSDASLAPAVRDRKMPYRVKNRAAAKRCREKTKQYEIDLANKEKQVTKEHMYLDACVVALKNEVLSLKNQILQHSSCDCDMIQGYIARTASTVSVAGNGVPTVSHPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7U4</accession>
    <name>E3Q7U4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_02127</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ26956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090976.1">
        <property type="nucleotide sequence ID" value="XM_008092785.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7U4"/>
    <dbReference type="STRING" id="645133.E3Q7U4"/>
    <dbReference type="GeneID" id="24407492"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02127"/>
    <dbReference type="eggNOG" id="ENOG502SH6N">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078277_0_0_1"/>
    <dbReference type="OrthoDB" id="5283654at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF9">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="34"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ26956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="297" mass="32393" checksum="A434B2C100A22834" modified="2011-01-11" version="1">MTLNRIAVYGHRGAVAKVLHRASSDISNLPTHITKVEIDVNDEPCLIEALQDIDIVVSLVGHEGVQRQHGFVRAIPKTNVKLFSPSDLAGRYDEQGLKIGVNKEKHELETAAPAAGIPTTVVLIGNFAEFALNTMGMVVDLAGNKITYSGNSADEKLNICTRKYVAAAYVSIFSTTPISQLKNRAIALCELVPTGKDIAAMMETKHGIAPQTSSHGLEKVNGEVEKGLESGSLFTLAWYCRKIWGAGQQVQMIGSDLWEVDGYKKATLEDLILGGELGAYREMPAQVVEYFRHCFQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q865</accession>
    <name>E3Q865_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">T-complex protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_02248</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091097.1">
        <property type="nucleotide sequence ID" value="XM_008092906.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q865"/>
    <dbReference type="STRING" id="645133.E3Q865"/>
    <dbReference type="GeneID" id="24407613"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02248"/>
    <dbReference type="eggNOG" id="KOG0362">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008891_4_2_1"/>
    <dbReference type="OrthoDB" id="1748577at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd03341">
        <property type="entry name" value="TCP1_theta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000008">
        <property type="entry name" value="T-complex protein 1 subunit theta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012721">
        <property type="entry name" value="Chap_CCT_theta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02346">
        <property type="entry name" value="chap_CCT_theta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ27077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="547" mass="59415" checksum="15AAF5E9B5F34A16" modified="2011-01-11" version="1">MSLNIPNAPNANLFKQGYNNYDSEDGAVLRNIDACRAISSTVQTSLGPYGRNKIVINHLQKMILTSDAATILRELDVVHPAAKLLVMASQQQESEMGDATNLVIVLAGELLKKAEDLLRMGLKTADIVTGYERAQKFALETLDELSVDKVEDIRSQEELSKAIRTVVASKQNGSEDFLSDLVAEAVLAVLPKNPAGFNVDNIRVVKIMGGALEQSRVVKGMVFPKEPDGSVKKAQRAKVGVFSCPIDNSQTETKGTVLLHNAKEMMDFTKGEESHLEAAIKELYDVGIRVVIAGSTVGELALHYLNRFGILVIKILSKFELRRICRVVGATPLARLGAPMPDEMGSIDVVETLEIGGDRVTVFRQENEATRTATLVLRGATQNHLDDVERAVDDGVNVVKAITRDPRLVPGAGATEIQLVERLNALGEKTPGLSQYAIRKYGEAFEVIPRTLAESAGLDATEVLSRLYMAHHKKDDWATGVDIENDDGSGTLDAREEGILDLLVSKSWAIKLATEAARTVLSVDQIIVARRAGGPKPPGPNPNWDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8E7</accession>
    <name>E3Q8E7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Plasma membrane ATPase</fullName>
            <ecNumber evidence="10">7.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_02330</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O + H(+)(in) = ADP + phosphate + 2 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:20852"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.1" evidence="10"/>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091179.1">
        <property type="nucleotide sequence ID" value="XM_008092988.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8E7"/>
    <dbReference type="STRING" id="645133.E3Q8E7"/>
    <dbReference type="GeneID" id="24407695"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02330"/>
    <dbReference type="eggNOG" id="KOG0205">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002360_6_0_1"/>
    <dbReference type="OrthoDB" id="116380at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008553">
        <property type="term" value="F:P-type proton-exporting transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120029">
        <property type="term" value="P:proton export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000005">
        <property type="entry name" value="Plasma membrane ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000008">
        <property type="entry name" value="Plasma membrane ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006534">
        <property type="entry name" value="P-type_ATPase_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01647">
        <property type="entry name" value="ATPase-IIIA_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="172"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="364"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="396"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="758"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="785"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="821"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="859"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="887"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="932"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="12">
        <location>
            <begin position="95"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ27159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1011" mass="111084" checksum="83166A796FBDC901" modified="2011-01-11" version="1">MAGLIGKGGNKHYPQPISTEDEDQDLETGNFIQERARNNRVEGAAGENGTNEEYRSLVRYIETYRDPNAEVEEADAPTVKKVPKWMFWKKAAAEGAGSSAFVTPADWLKTDMKQGLDPAEVERRRKYTGWNELTTEKENMFLKFVGFFRGPILYVMECAAILAFALQDWLDAGLIVAILLLNAAVGWYQEKQAADVVASLKGDIAMKARVIRSGREEEIRARELVPGDIIIIEEGHVVPADCQLICDYENPAGYAAYKAELEAQDVMSPRREKFEEGDEENANPQLGHAIVAVDQSAMTGESLAVDKFMTDTCYYTTGCKRGKAFCIVTHGAQASFVGKTASLVQGAQDQGHFKAIMNSIGTTLLALVIIFILAAWIGGFYRSISVSEEGTSVNLLHYALILLIIGVPIGLPCVTTTTLAVGAAYLAEEKAIVQKLTAIESLAGVDILCSDKTGTLTANQLSVREPFVMEGVDINWMMAVAALASSHNIKALDPIDKITVLTLKRYPKAKELISDGWKTEKFTPFDPVSKRITTIATHRGVRYTCAKGAPKAVLALTDCTEEQSALFKEKAAEFARRGFRSLAVAVKEEDGPWEMLGMLSLFDPPRSDTGQTILEAQALGLQVKMLTGDAHAIAVETCRMLQLGTKVYNSDKLLHSDMAGTSIHDLCERADGFAEVFPEHKYQVVEMLQQRGHLTAMTGDGVNDAPSLKKSDCGIAVEGATEAAQAAADIVFLAPGLSTIVSAIKLSRQIFQRMKAYIQYRIALCLHLEIYLVTSMIIINETIRADLIVFLALFADLATIAVAYDNAHFEKRPVEWQLPKIWIISIVLGGLLAIGTWILRGTMYIVEGGVIHEYGSIQEILFLEISLTQNWLIFVTRGFETFPSFQLIGAIAAVDVLAILFCVFGWFSGGRGEPANPPSINRFLSDDGRTDFVTVCVVFVYSVAVTIVMALVYYVLSNLRSLNDMGRKKRSVTDTLIENVLTQLSKVALEHEKDDKGERFYIANRAVVEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9R7</accession>
    <name>E3Q9R7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Mediator of RNA polymerase II transcription subunit 21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_02749</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 10">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the Mediator complex subunit 21 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091625.1">
        <property type="nucleotide sequence ID" value="XM_008093434.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9R7"/>
    <dbReference type="STRING" id="645133.E3Q9R7"/>
    <dbReference type="GeneID" id="24408114"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02749"/>
    <dbReference type="eggNOG" id="KOG1510">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094271_1_1_1"/>
    <dbReference type="OrthoDB" id="526653at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.10">
        <property type="entry name" value="Mediator complex, subunit Med21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037212">
        <property type="entry name" value="Med7/Med21-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021384">
        <property type="entry name" value="Mediator_Med21"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13381:SF0">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13381">
        <property type="entry name" value="RNA POLYMERASE II HOLOENZYME COMPONENT SRB7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11221">
        <property type="entry name" value="Med21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140718">
        <property type="entry name" value="Mediator hinge subcomplex-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0010">Activator</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 10" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="93"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ27605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="138" mass="15948" checksum="42D333E6A0949503" modified="2011-01-11" version="1">MGDRLTQLQDAVDQLAQQFVASFHFVHRRHDLELLGPNDKIREVKQDPEQKEVDPLPPDEFKDGLAELARDLIIKEQQIEVLISTLPGLDSSEADQERYIQELEDELKVAEAQRQDAIKEKDQILTKLDEVIRGIRRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9T1</accession>
    <name>E3Q9T1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Actin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_02763</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the actin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091639.1">
        <property type="nucleotide sequence ID" value="XM_008093448.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9T1"/>
    <dbReference type="STRING" id="645133.E3Q9T1"/>
    <dbReference type="GeneID" id="24408128"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02763"/>
    <dbReference type="eggNOG" id="KOG0676">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015497_0_0_1"/>
    <dbReference type="OrthoDB" id="74201at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="51"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="443"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="728"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="73"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="86"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="492"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="529"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="728"/>
            <end position="737"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ27619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="833" mass="89621" checksum="6BDC967CFAF3052A" modified="2011-01-11" version="1">MKPCKLMKVDCACNHCKSRRKDNANMDARTMWQPLGMASFGMGSATPAASCDSNSYATRLRPRSCPPSAPVTPKKKTPRKSKKAPPQKGGAATPGTQGTPVCIDSKKTPSGAQKAARVGNMSTQTGKFREDQVLIICPGSQTTMAQLGCGELTPPIHRIPTRMFKDAETDEWRPFHTFKRKKPSAKGALAIDGPRVDEDEYEWVEDTDSTEGAVYPLQGGRIVNMEAFLAFLDHVHSMLTTTYHNTPIMLMASPQWCRPDIETLARYIFEKTRTPALCMIHSGIATQYGLKWPALTVVDIGYEKVDVTCIHEGRVVNHGELGAPNPERFISGGEMFTRKLLEKLKDKGFTYDMAEQLKKSHICEVLPYAPNSPDLMELPTDQTAGIAAGAPIPDAVAAHEPAARSGLPSSIEEELEEKVADEGVLDVAAIVTTGNAREFLAKKEKEKQKGGRKVKAGQEVETAKQVRLPNSKRTHNIFHLEEVVMEEVQLPKPEEAKPEDKEEPKKEESGSAVEPKDVEMTDGPKPADDAAPAPTDSEVKPAETPAPAAPTDSAVSPAAPETNGTTAQAAAAAAAAAASTTTTNGAPQSPQLQAKRVRRDIEVGPERFTFADRGEIDRIVTTIYRTVQGIEDMYMRPACWDNLVFVGNGSRLRGLKDNILQTLVARHLISPSTATMFTSELPSNVATPTGTGAQTPTGSFTGVPLQLPVNVAAGGSSGVNPLLQAATTASAQNQGTPGPSGGADAVGNHSGHHFHSQTPTSIKLATLPTYLSEWNKNGFEEAMFLGAQVAARIAFCQHNLDMAGLEAQRQASLSRVDYNELGPKGIRTHSMLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QA80</accession>
    <name>E3QA80_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_02912</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091788.1">
        <property type="nucleotide sequence ID" value="XM_008093597.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QA80"/>
    <dbReference type="GeneID" id="24408277"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02912"/>
    <dbReference type="eggNOG" id="ENOG502S06P">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071891_0_0_1"/>
    <dbReference type="OrthoDB" id="5220781at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="230"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ27768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="330" mass="36531" checksum="E2BBB661405E2291" modified="2011-01-11" version="1">MPPLRPWGPIFEEITLPQNRMSSTVFSMLPTSLQSRLPPLRSIRKSASMQTLSSSRQSHTRSLSGLDGMHPNITQARIISESTEEHMSLVATEHHQSRTYEMRSAADKHEQDRRQAEQYRLQQQEAASQCSNVDWRFAQQGLALIAVAQDELRQPSRRPAVDFERKAFLDGVEYILKALPSDLNEHELHRLRTSTPSNFIPSTPPDSRAYSPSRGANHGRSILHRGVQTAVVNIFLIIHLALPYLILLLRLAARTEREYRISENLVGAGMGLANAIGSKGMRITGALCNVGDGRLGQALTEAIAWTVEGFTGGLSDGVGEGLSLVAPKRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAC3</accession>
    <name>E3QAC3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Chromo domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_02955</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091831.1">
        <property type="nucleotide sequence ID" value="XM_008093640.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAC3"/>
    <dbReference type="STRING" id="645133.E3QAC3"/>
    <dbReference type="GeneID" id="24408320"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02955"/>
    <dbReference type="eggNOG" id="KOG1911">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_855323_0_0_1"/>
    <dbReference type="OrthoDB" id="433924at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023779">
        <property type="entry name" value="Chromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051219">
        <property type="entry name" value="Heterochromatin_chromo-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22812">
        <property type="entry name" value="CHROMOBOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00598">
        <property type="entry name" value="CHROMO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="5">
        <location>
            <begin position="286"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="155"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="233"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="93"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="183"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ27811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="349" mass="38284" checksum="1F9D272CBA658A97" modified="2011-01-11" version="1">MSAPRVFKGREEEMTMEQLAASSAAAKIQSTSGGSEFEDLPLIKSDITSSPAVNARPVASETKKRKAGRPLKASRAVKNLTLAENPEVAVGTSQSAVPSAENSSSSPYATPDSPSLNRRKVLKVGEYFENVPNQRATPVTRMQSSARELSQGANVYNSDDDMRDDAIPEPVSVPTRRGRPRKNQTPIPVNTTGKGKSKTKLPRLVSRRLLPRRYAKTNRRGIIDSVRTTRASARIGSEKAAPAKTPQVQAVPTKRASLSYGRGVGRLKKTPRKGNSGTPQFTREEYVVEKIVGSRIDPITKEQMYMVKWKNYAAKDNTWEPVNNLGKCSSLIKTFTDSQKSKGKRKGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBF7</accession>
    <name>E3QBF7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_03440</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092316.1">
        <property type="nucleotide sequence ID" value="XM_008094125.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBF7"/>
    <dbReference type="STRING" id="645133.E3QBF7"/>
    <dbReference type="GeneID" id="24408805"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03440"/>
    <dbReference type="eggNOG" id="ENOG502SKB7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009555_0_0_1"/>
    <dbReference type="OrthoDB" id="5327538at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="383"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="473"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="397"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="475"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="500"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ28296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="668" mass="74884" checksum="72731F6974B6C58F" modified="2011-01-11" version="1">MAALPTPFYCLWQKEHSSLGSKVLDLLPKRDLASLRLANSACCNIATKPLFKRIRVTFSANTFTKQSRIQALARVGHHVEHLHFHFAHSEATFLPPLVHPITGREICFLYTPHTSMASVLARPKYANTELGEILTQQYPPLFHAATNVPSFINAMRYLVNIRHLTIRCPGQDPQERYRRDIVDYAIMSLRIAVERAPLERLEKLSLSGMHPSAFNYLRHVPGFGAVPSAGRRWKQIRKLNISVEAWDFYGPSPGLDHLKIIDDYIRQFSGTLEKLHFTWLGPKGPCPIALAADPLFAPPRQCKKLFNEVTSPMSPLPPAPSRKPMHFPRLRYMQVRNATMTASQLSDLVDAHQKTVKEYDFDNVVLINGGDWDEALAPLMEPASGSSSDIWSQHSRTNSEADSLHSVEASHDDDLPSPSAAAAAATRELLDFDLGSELYVDDEYDPYDPYEGLDEDLASDLAAAKEASTSFSTILKKKRVHRRRKHRKDDGGGGKEGSSSRHHGSRSHSRHRKHRHHREQPPVPEEDDVFFRPSTPVPNITAPIQDMSPHPVLLQPAVYDPSANRYTSPEDGISSVQRNIEQEEAHRMLAEDAAMRVSALRKAKAAVLMKLTKEFTRKGTPAPAAGRDNCGLQMRLREGLFGRSFVSVLPDDRTMSSQSAIVPLMVMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCF4</accession>
    <name>E3QCF4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_03686</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092562.1">
        <property type="nucleotide sequence ID" value="XM_008094371.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCF4"/>
    <dbReference type="STRING" id="645133.E3QCF4"/>
    <dbReference type="GeneID" id="24409051"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03686"/>
    <dbReference type="eggNOG" id="ENOG502QWIX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010595_11_3_1"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF10">
        <property type="entry name" value="ABC TRANSMEMBRANE TYPE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ28542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="202" mass="22386" checksum="2B627EFEE5E954D0" modified="2011-01-11" version="1">MSEPGANPATASSMPSPNTVTVEDVPSSIEVDEAFLTDDASAIEDRLSSYTASLTSSIIDYPKEYGRRYHAYRSGSYQFPNDKREMDRLDLSHSLVVKTIGSLFLAPVDTEKTHRILDVGTGTGIWAIEVGDMFPNAEVVGIDLSAIQPEFVPPNVRFEIDDAESAWVGPSYDFIFLRYLALSIADWPKLVNNIYTNLNNNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCM2</accession>
    <name>E3QCM2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_03754</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092630.1">
        <property type="nucleotide sequence ID" value="XM_008094439.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCM2"/>
    <dbReference type="STRING" id="645133.E3QCM2"/>
    <dbReference type="GeneID" id="24409119"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03754"/>
    <dbReference type="eggNOG" id="KOG2495">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021377_1_2_1"/>
    <dbReference type="OrthoDB" id="3244603at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003954">
        <property type="term" value="F:NADH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045024">
        <property type="entry name" value="NDH-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054585">
        <property type="entry name" value="NDH2-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706">
        <property type="entry name" value="NADH DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706:SF17">
        <property type="entry name" value="NADH DEHYDROGENASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22366">
        <property type="entry name" value="NDH2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="7">
        <location>
            <begin position="56"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="External alternative NADH-ubiquinone oxidoreductase-like C-terminal" evidence="8">
        <location>
            <begin position="453"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="13"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF22366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ28610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="516" mass="58496" checksum="29E743C1802FC5AF" modified="2011-01-11" version="1">MASSKVARQYWRSLARPEHRSPAGTALRTGATTNTSVVNYRNSTSSNSPTERKRERVVVLGSGWAGYAFARELDPKKFERILISPRSYFVFTPLLASTSVGTLEFRSILEPVRWLNLDSFYEAWADDVDFSKKLVRVEKVTSQDATSRTLPERQLHRSKGEVIDVPYDKLVISVGAYSQTFGIEGVKEYANFLRDIGDARSIRLRVLQCFEKADWPTTTDEQRRKMLHFAVVGGGPTGIEFAAELHDLIHDDLSKLYPHLMEFVSITIYDIAPKVLPMFEQQLASYAEDLFRRQGIKVKTQHHLQRIRSDEDDTYNTLKLKIKEYGDEEVGAGLVVWSTGLMQNPLIQKILKKELRNPASAVEGKRSEIVKVLKAERSGGIITDSHLRVRLDDPDNEKAVLPDVYSLGDCSVLETGTLPATAQVASQQAVYLAKMLNRAADDRGSKPFKFRNLGTMAYLGSWRAIHQSSADELKGRAAWILWRCAYLTKSMSIRNKILVPFYWFITWVFGRGISRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCR7</accession>
    <name>E3QCR7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Mitochondrial import inner membrane translocase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_03799</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Mitochondrion inner membrane</location>
            <topology evidence="1 8">Peripheral membrane protein</topology>
            <orientation evidence="1 8">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the small Tim family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092675.1">
        <property type="nucleotide sequence ID" value="XM_008094484.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCR7"/>
    <dbReference type="STRING" id="645133.E3QCR7"/>
    <dbReference type="GeneID" id="24409164"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03799"/>
    <dbReference type="eggNOG" id="KOG3489">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141397_1_0_1"/>
    <dbReference type="OrthoDB" id="344165at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.810">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit tim13 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004217">
        <property type="entry name" value="Tim10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035427">
        <property type="entry name" value="Tim10-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02953">
        <property type="entry name" value="zf-Tim10_DDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144122">
        <property type="entry name" value="Tim10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4 8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0811">Translocation</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Tim10-like" evidence="9">
        <location>
            <begin position="26"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ28655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="94" mass="10775" checksum="164FDA90B8EB4DB9" modified="2011-01-11" version="1">MDSSRSALENSDLEKLNDKDKLELRQFLANEQQRSQIQSQTHALTEICWKKCVTGSIRNSKLDKGEEGCLANCVDRFLDVNFLTMKHLNNMRSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDL4</accession>
    <name>E3QDL4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_04096</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ28952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092972.1">
        <property type="nucleotide sequence ID" value="XM_008094781.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDL4"/>
    <dbReference type="STRING" id="645133.E3QDL4"/>
    <dbReference type="GeneID" id="24409461"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04096"/>
    <dbReference type="eggNOG" id="KOG1269">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010595_0_0_1"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF10">
        <property type="entry name" value="ABC TRANSMEMBRANE TYPE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="18"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="79"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ28952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="392" mass="43092" checksum="68BC9B2E09E0A0C4" modified="2011-01-11" version="1">MASEQPVDQATAPPPAAAPATAPEAAPEATPEAAPEAAPEAAPTEPQQTTAPAENDAGILPAEHWVQAAHDAASEGDADSALGDDAASSTASIGSTIMQYRKIHGRTFHAEVGDAQYWGSNDEKQNEAWDINHHLLTLSMGDRLYLAPLDKSKAILDVGTGTGIWAIDFADENPDCEVIGTDISPIQPSWVPPNLKFEIDDCTREWTFEPESFDYVHIRFLVGSIADWPALFKEAYRALKPGGYLESFEVSPVILSDDGTVPETSALGQWGKFFEEGGRKMGRSFRVLDEGMQRIAMEEAGFENINEWNNKAPIGNWPKDPVKKEIGEWAQLALLSDIEGYVLFMANVMSTWTREEILVYAAQLRRETRSGKFHGYYRQRVVWGQKPLKTDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDV3</accession>
    <name>E3QDV3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rhamnogalacturonase A/B/Epimerase-like pectate lyase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_04185</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093061.1">
        <property type="nucleotide sequence ID" value="XM_008094870.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDV3"/>
    <dbReference type="STRING" id="645133.E3QDV3"/>
    <dbReference type="GeneID" id="24409550"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04185"/>
    <dbReference type="eggNOG" id="ENOG502SH8Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002540_1_0_1"/>
    <dbReference type="OrthoDB" id="1046782at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004650">
        <property type="term" value="F:polygalacturonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23668">
        <property type="entry name" value="GH55_beta13glucanase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.20.10:FF:000049">
        <property type="entry name" value="Putative exo-beta-1,3-glucanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039279">
        <property type="entry name" value="QRT3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024535">
        <property type="entry name" value="RHGA/B-epi-like_pectate_lyase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33928:SF2">
        <property type="entry name" value="PECTATE LYASE SUPERFAMILY PROTEIN DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33928">
        <property type="entry name" value="POLYGALACTURONASE QRT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12708">
        <property type="entry name" value="Pect-lyase_RHGA_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180356" description="Rhamnogalacturonase A/B/Epimerase-like pectate lyase domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="domain" description="Rhamnogalacturonase A/B/Epimerase-like pectate lyase" evidence="2">
        <location>
            <begin position="59"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ29041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="770" mass="81994" checksum="2CACA896E909CB17" modified="2011-01-11" version="1">MKLLPLLAVLGIGAVAQPLESRQTCSGPVESNPSTWWRAAIGHNGTAPTSTDSTYQYYRTAVQYGADNTGVQDSSDAFNFAIEAWSRTGNTVTTRPAYIYIPPGRYRIKKPIQMLVTTYLVGDALNPPVLIADPALGNQPVINGYDSHQGDGSATKNFYMAVRNVVVDTTEIDTGVQAVGIDWSVSQGCSLSNVKVRMPNYSSHIGITMSAGGSGILISDSQFEGGAIGIKVNGQQYQFKNLSFNGCNVGISVDHVFVAVVQGATFANCNFGIDMGGNTAGVVSLVDSSVSACNAGVNTRVTGYGENSLVIDNFQVTGSTAVKSAADGSTLRSGSVPAGQTWVVGYVNSNNLQGGTTYPIERPAALLSGNRYFTAPLPQYEKYALDQFVSLKGDPQFPVYGDNSHDDGPNINAILQKYKGCKIIFVPQGIYLTRETIYVPPGTRLIGETLSIINGLGSQWWNPDDPQPILKVGNPGETGIAQITDITVEVADVQQGATLVQINMAGSNPGDVGIWSSVFRVGGTKHSLVNTNCGGADPGACKAAFALMHVTSTASAYLENVWGWVADHSLDGGAAQNIAVGRGALIESTKPTWLVGTSFEHCVMYQYNLHNAQNVYISLQQTESPYWQGQGTPQRAPGPWSVLPAYGDPDFSNCAAQGQGNNDRCFRSWGHHMTGSSKVVIHGSALWVFFNKMNDNQWQNAQCENTGGNCMTNQAFANGAKSTYWFGLSSKSTTTLLYDQTGGVVWEVFASDNTGSWGGVLAAYLRDSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEA4</accession>
    <name>E3QEA4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04336</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093212.1">
        <property type="nucleotide sequence ID" value="XM_008095021.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEA4"/>
    <dbReference type="GeneID" id="24409701"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04336"/>
    <dbReference type="HOGENOM" id="CLU_2819410_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="67" mass="7866" checksum="DCA4902351D045DD" modified="2011-01-11" version="1" fragment="single">HTPHTQSPASWPNIPAFFRPRIPHSSKKKLLATHPPPPQSIFPQPSRFGPTRIDYRRPNFWKRETEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEJ4</accession>
    <name>E3QEJ4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04444</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093320.1">
        <property type="nucleotide sequence ID" value="XM_008095129.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEJ4"/>
    <dbReference type="STRING" id="645133.E3QEJ4"/>
    <dbReference type="GeneID" id="24409809"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04444"/>
    <dbReference type="eggNOG" id="ENOG502SS66">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040692_1_0_1"/>
    <dbReference type="OrthoDB" id="5366256at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="432" mass="46568" checksum="A0A401F634CAF324" modified="2011-01-11" version="1">MVSGFPEQGCEDSYSLPPRSRAGSRVSATAAQFANIQLVDSPRTLPLESSPSVRSEALHSSGYISPNPPGSATFLPSPNPQGYSPFPLLPPDILNAEWNEHEVHQTSGSAPLVRVDPAQDYSSNQSSPPLLAEASMSAIAMQFDPSFTMGSRSSFTWPGLDNSESSGALLGHNLSSLGHVPDTSLTPPSGSRSVTSSPPRGTLTLEQRELKKQRDMARRDSKTSQRVRRAGSNPYVHSPPLSLPDISSTMGVPIYTTAPAPISLLSEPTTTMGSSSYLPSYSPPLSDHGYQSGYPPMASAYGMGGGMDYSQQFQQPTHYGSRPQMPVGQDPGMMYGVPPSMSGGPGTPDQGHVRVVQSRPKPQCWEHGCNGRQFSTFSNLLRHQREKSGQATKATCPNCGAEFTRTTARNGHLLHDKCKQQQQQQQQQRRNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEM6</accession>
    <name>E3QEM6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_04476</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093352.1">
        <property type="nucleotide sequence ID" value="XM_008095161.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEM6"/>
    <dbReference type="GeneID" id="24409841"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04476"/>
    <dbReference type="HOGENOM" id="CLU_2359597_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ29332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="96" mass="11113" checksum="192F289F2751DF99" modified="2011-01-11" version="1">MIYTPPRIHLKVSPDSLRFEALIANCNVIYGHWLIRMMPRRLTWPETPTASGQVEMRDEVSAERVLRSPKLDLVEPTRYACKMPMSRAKDGFVDPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEP2</accession>
    <name>E3QEP2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">OPA3 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_04492</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the OPA3 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093368.1">
        <property type="nucleotide sequence ID" value="XM_008095177.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEP2"/>
    <dbReference type="STRING" id="645133.E3QEP2"/>
    <dbReference type="GeneID" id="24409857"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04492"/>
    <dbReference type="eggNOG" id="KOG3335">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074707_2_0_1"/>
    <dbReference type="OrthoDB" id="2129069at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019216">
        <property type="term" value="P:regulation of lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010754">
        <property type="entry name" value="OPA3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12499:SF0">
        <property type="entry name" value="OPTIC ATROPHY 3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12499">
        <property type="entry name" value="OPTIC ATROPHY 3 PROTEIN OPA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07047">
        <property type="entry name" value="OPA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="64"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="233"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="64"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="105"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="250"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ29348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="263" mass="29271" checksum="51A70C22AB2F96FF" modified="2011-01-11" version="1">MVPLPLFKLAALFVRHVSKYGANRIKAQAHEHPKFRAFAARYGQSIHQLNMRLNVALLRNPDAEQRAREKTEAPTVKTKEQVEKEEAAKARQANSDAAKRKPLVPTASSESSSPSSSSSSSISESGSTASSSSTTGSSTKEKPKSVWRRKFRPLPENKAVDLFADVIGDAFILGVASAIIVYEYWKASQKPDQNAERIRVLDEKLEELTRRERELAQREDERSQRYLAMEAALRDLRDPKTKKPLLSDLQLPTQSQSPASTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEU4</accession>
    <name>E3QEU4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Dipeptidase</fullName>
            <ecNumber evidence="2">3.4.13.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_04544</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>an L-aminoacyl-L-amino acid + H2O = 2 an L-alpha-amino acid</text>
            <dbReference type="Rhea" id="RHEA:48940"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:59869"/>
            <dbReference type="ChEBI" id="CHEBI:77460"/>
            <dbReference type="EC" id="3.4.13.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.13.19" evidence="2"/>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093420.1">
        <property type="nucleotide sequence ID" value="XM_008095229.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEU4"/>
    <dbReference type="STRING" id="645133.E3QEU4"/>
    <dbReference type="GeneID" id="24409909"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04544"/>
    <dbReference type="eggNOG" id="KOG4127">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031404_4_0_1"/>
    <dbReference type="OrthoDB" id="445695at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070573">
        <property type="term" value="F:metallodipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01301">
        <property type="entry name" value="rDP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008257">
        <property type="entry name" value="Pept_M19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10443:SF12">
        <property type="entry name" value="DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10443">
        <property type="entry name" value="MICROSOMAL DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01244">
        <property type="entry name" value="Peptidase_M19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51365">
        <property type="entry name" value="RENAL_DIPEPTIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU341113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ29400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="418" mass="46653" checksum="0FEB4A709B5C0DEC" modified="2011-01-11" version="1">MAQAVHPYQKLDIDERVKRVLLKTPLIDGHNDLPQQPRACFHGKIHNNPKFDLAGGFERGMTDIPRLREGAVGGQFWSVCVPCLRSAENFSTPEYSDMARDAIEQMDLTLRLIESYPETFELVNGPDDVKGIYESGRIACSIGIEGLHMAGNSIGIIRAFYRLGVRYCTLTHVCNNAFADSSTSKIGPVHGGLSKLGRSAVVEMNRLGMIVDISHVSEDCAKQVLELSRAPIMFSHSNVKGVFDCPRNVPDHILDMVPANGGIVMVTFVPEHVATRRRDARMDMVLDHLFYVAARVGWDHVGLGSDFDGIASVIPGLEDVKCYPSLLKAILDRGATEEQLAKVAGENILRVWRGVEKVRDEMKAEGVLPVEDVWEDRTWWRYDGYYQMPDPDPEDKLGLDWYGVPPPDEGLYLEDKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFR2</accession>
    <name>E3QFR2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CID domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_04891</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093767.1">
        <property type="nucleotide sequence ID" value="XM_008095576.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFR2"/>
    <dbReference type="STRING" id="645133.E3QFR2"/>
    <dbReference type="GeneID" id="24410256"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04891"/>
    <dbReference type="eggNOG" id="KOG4368">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021915_1_0_1"/>
    <dbReference type="OrthoDB" id="21470at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006569">
        <property type="entry name" value="CID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12323:SF0">
        <property type="entry name" value="CALCIUM HOMEOSTASIS ENDOPLASMIC RETICULUM PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12323">
        <property type="entry name" value="SR-RELATED CTD ASSOCIATED FACTOR 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04818">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51391">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CID" evidence="2">
        <location>
            <begin position="25"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="342"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="398"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="455"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="482"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="515"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="538"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="548"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="565"/>
            <end position="579"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ29747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="579" mass="64762" checksum="95C3876848CA22E8" modified="2011-01-11" version="1">MANPELAIAKASFSAILFRKEPVSLIRSEIDTFHALLHDAINQCSPANVQKCKRWILKNLVPSPPRVAALGKYLSALSNSLPDEAKTKPSTRRRRLHILYILNDVLYHAVVRHQVARIATDLEASLTTLLHGAAKFRNCPKQTRKVEDLLALWEKHNYFSAATIDGLREAVKEAPNGEKVSKAMTQDQAGSNLGSKLPKDAPYMIPSIHGDPNTPWFDLPAANWLPHLTPNSTKPMNPDMIKPLQLAPGPADKVLANAVKNLLVDVERLYSKHVPPQAADSQQHMDVSEMGERIVLDEITGEIVDGETYYGWSRRFCEQMKQRRKKATKGDDGRGRGRSYSRSRSYSYSPGRSSGSDSVPAFKRRKLSPDLQSPSRSRSRRRSVQHDRYDSRYTPSRSRSRSSSRRRYKSRSRSRDRRPRRDESRTSKSPPPNHNRHNPEFRPGYYDRGSSHNQQPPPPTYHNSPAFPPYPPPLPLASGLSPFPPPPPQGYQGQWPPPPPPPPPPPPLPPHMGNSLLPHSWSSPPGSGVPPSHTSGWAPPPPPPPPQQQQHQSQQFGRGNGGYRGRGERGGYDRGRNGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QG21</accession>
    <name>E3QG21_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="13">DAK2 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_05000</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-glyceraldehyde + ATP = D-glyceraldehyde 3-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13941"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.28"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>dihydroxyacetone + ATP = dihydroxyacetone phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15773"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16016"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.29"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Polyol metabolism; glycerol fermentation; glycerone phosphate from glycerol (oxidative route): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the dihydroxyacetone kinase (DAK) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093876.1">
        <property type="nucleotide sequence ID" value="XM_008095685.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QG21"/>
    <dbReference type="STRING" id="645133.E3QG21"/>
    <dbReference type="GeneID" id="24410365"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05000"/>
    <dbReference type="eggNOG" id="KOG2426">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017054_1_0_1"/>
    <dbReference type="OrthoDB" id="1724672at2759"/>
    <dbReference type="UniPathway" id="UPA00617">
        <property type="reaction ID" value="UER00669"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004371">
        <property type="term" value="F:glycerone kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050354">
        <property type="term" value="F:triokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019588">
        <property type="term" value="P:anaerobic glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.340:FF:000001">
        <property type="entry name" value="Dihydroxyacetone kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1180.20">
        <property type="entry name" value="Dihydroxyacetone kinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004006">
        <property type="entry name" value="DhaK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004007">
        <property type="entry name" value="DhaL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036117">
        <property type="entry name" value="DhaL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050861">
        <property type="entry name" value="Dihydroxyacetone_Kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28629:SF14">
        <property type="entry name" value="DIHYDROXYACETONE KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28629">
        <property type="entry name" value="TRIOKINASE/FMN CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02733">
        <property type="entry name" value="Dak1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02734">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01120">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82549">
        <property type="entry name" value="DAK1/DegV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101473">
        <property type="entry name" value="DhaL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51481">
        <property type="entry name" value="DHAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51480">
        <property type="entry name" value="DHAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DhaK" evidence="12">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="DhaL" evidence="11">
        <location>
            <begin position="141"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ29856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="347" mass="36135" checksum="14E99E96D4D2E8D4" modified="2011-01-11" version="1">MLAQLLDQGDKDRAFLNVNSNEVVLLVNNLGGVSALELGGITAEVALQLEGSYGIHPVRILSGTYMTSLNGLGFSISLLNIVNTDIGGPSMIQLLDYPTEATGWSSPVLKETWEAKNEATREEEADTSQATKPSDLKYDAAAATKSITAALQRVIAAEPDITKYDTVVGDGDCGIGLKRGAEAILKHISEKPLTGDAVVDLASAVPVVESTMDGTSGALYAIFLNALTGALRGLAPGAADPKVWAAALKQSSEAMARYTPARPGDRTLVDALHPFVDVLGQTADVKKAAEAARAGAEKTKGMKASLGRTVYVGGSGFEQVPDPGAWGLSCFFAGLAGIEGEDGWEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGS0</accession>
    <name>E3QGS0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal protein/NADH dehydrogenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_05202</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ30058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094078.1">
        <property type="nucleotide sequence ID" value="XM_008095887.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGS0"/>
    <dbReference type="STRING" id="645133.E3QGS0"/>
    <dbReference type="GeneID" id="24410567"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05202"/>
    <dbReference type="eggNOG" id="ENOG502SDFJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094283_0_0_1"/>
    <dbReference type="OrthoDB" id="1696305at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007741">
        <property type="entry name" value="Ribosomal_mL43/mS25/NADH_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040049">
        <property type="entry name" value="Ribosomal_mS25/mL61"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13274">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN S25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13274:SF2">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05047">
        <property type="entry name" value="L51_S25_CI-B8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00916">
        <property type="entry name" value="L51_S25_CI-B8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein/NADH dehydrogenase" evidence="6">
        <location>
            <begin position="37"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="171"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ30058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="194" mass="21816" checksum="AA8EC2E09A1A1590" modified="2011-01-11" version="1">MVRVGQRWHALRAIRFGPGAATLPPNVTRIHMEFAKRAENGHVGPKKFWREMLPRLKYYNPAVPMIVNRKANTEGAAVMSVYFSATDAPVDPATLPQPPSSAIDNSKAQPPLEGVERVVKIDMKGKHSQEILDRFLAETKAEAILPGPEDEREMKAAEELRIKGEKDRQRNLKIREEENKEKAMLARARAEVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QH39</accession>
    <name>E3QH39_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_05345</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697348">
        <property type="protein sequence ID" value="EFQ30201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094221.1">
        <property type="nucleotide sequence ID" value="XM_008096030.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QH39"/>
    <dbReference type="STRING" id="645133.E3QH39"/>
    <dbReference type="GeneID" id="24410710"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05345"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_9_0_1"/>
    <dbReference type="OrthoDB" id="1933717at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43963">
        <property type="entry name" value="CARBONYL REDUCTASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43963:SF6">
        <property type="entry name" value="CHAIN DEHYDROGENASE FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G15350)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ30201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="247" mass="26425" checksum="3BC12AB3EB6D70B3" modified="2011-01-11" version="1">MSKESADPTIALVTGANQGIGYEVAKRLSSEYPNFHVFMAGRRQDAVEKAAAELQSAGLNVEPLVMDITSDDSIASAVEKVQAKFGHLDVLINNAGILSGKPEDSIRQRLTTVYNTNVFGSIAATEAFMPLLHNSSKTRRVVFVSSRLGSLAVRTDSEIGYPPIELLEYGSSKAALNHAAMTFAARFRNDNSWKVNVCCPGHCATNMSGYTGIDEASIGSIQAVRLATLDSNGVTASFSDRHGPAPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>E3QH97</accession>
    <name>E3QH97_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_05403</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697348">
        <property type="protein sequence ID" value="EFQ30259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094279.1">
        <property type="nucleotide sequence ID" value="XM_008096088.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QH97"/>
    <dbReference type="GeneID" id="24410768"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05403"/>
    <dbReference type="HOGENOM" id="CLU_1142527_0_0_1"/>
    <dbReference type="OrthoDB" id="4800268at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ30259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="243" mass="27556" checksum="CDB72A2D422C33EB" modified="2011-01-11" version="1">MPSFTRMLRQNGRIIGHVKDNVAFLNNNPKPEIPERDTRAGNIGPVDDICENDFPDTESPTAELLRLSQSPSTVEVLQTLLDELGKKLRERKAAINALGEARETLDGVVWTIAPYDYAMFMAGQEVPPEEEEWHGICPRARRQAHEWLYQRGRVTSRIDRFGQEVEELQRNITAVFAAMRQADDIQNICRRASMGPAELPLWKIPLVEKAHEIRQRQSDHENILKGRGGSIRFASMESGSGWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHJ2</accession>
    <name>E3QHJ2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05307</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697348">
        <property type="protein sequence ID" value="EFQ30163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094183.1">
        <property type="nucleotide sequence ID" value="XM_008095992.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHJ2"/>
    <dbReference type="STRING" id="645133.E3QHJ2"/>
    <dbReference type="GeneID" id="24410672"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05307"/>
    <dbReference type="eggNOG" id="ENOG502SPCU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031640_1_0_1"/>
    <dbReference type="OrthoDB" id="1046782at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="428"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="469" mass="53009" checksum="24558AE6914A70F8" modified="2011-01-11" version="1">MFNAERQRLLDSCRWSPGEGQLGYFEVWADDCAAGSVADSFRTGFLDDDEVEQWLHQQRRFSRRAMFGEAESTMRIRLLMCERVGWLPLGFAMSRSSFLAMQTAFRLSTEMLPALDANNGEKYSNLRFGAHNKNRPEFIALTAKLPQMSQLGNLGLAMSHHLETDTTVAFLHGWNMFCDRDYVTKEPIIPHAKSLHETMQSATTTLWAHPLFLPIVLMREHLSRAETFKRQLGANMTDIEKVLGVTNAARLMRSGVDAFAKRMVQDEEKRLQITARLLTTAKNVVNILGVLEWDLQYAKFLGRVSGELGAIHGQMSPAADAELRSIVDYLRCEALSLVSFVGAMKSKLDLQLTVLYNYIAQAENNLDRRNAANAGLDSTAMKTLAVVTMVFLPPPPGPQTIFSMSMFGWQGASSTAGDTKRTVVPELWIYWAVSIPLTLVIVIGWRVWWHFQKSYYENKYSSVKTERNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3QI38</accession>
    <name>E3QI38_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PI-PLC Y-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05670</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697349">
        <property type="protein sequence ID" value="EFQ30526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094546.1">
        <property type="nucleotide sequence ID" value="XM_008096355.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QI38"/>
    <dbReference type="GeneID" id="24411035"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05670"/>
    <dbReference type="HOGENOM" id="CLU_2413132_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004435">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate phospholipase C activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001711">
        <property type="entry name" value="PLipase_C_Pinositol-sp_Y"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50008">
        <property type="entry name" value="PIPLC_Y_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PI-PLC Y-box" evidence="1">
        <location>
            <begin position="2"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="92" mass="9783" checksum="478C0430F79B5DCD" modified="2011-01-11" version="1">MEVTSLANTALKLSATSGGYQLSATSTVANKASRIVPRGMRVMDKRYGPSPLGYPGCAVLKVSQWEGFRADLTAKSTEKALHLQASEIPRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QI61</accession>
    <name>E3QI61_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05820</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094696.1">
        <property type="nucleotide sequence ID" value="XM_008096505.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QI61"/>
    <dbReference type="STRING" id="645133.E3QI61"/>
    <dbReference type="GeneID" id="24411185"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05820"/>
    <dbReference type="eggNOG" id="ENOG502S8V6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098389_0_0_1"/>
    <dbReference type="OrthoDB" id="5689at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050276">
        <property type="entry name" value="MshD_Acetyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43617:SF9">
        <property type="entry name" value="GNAT FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43617">
        <property type="entry name" value="L-AMINO ACID N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="187" mass="20983" checksum="A569257F317222B9" modified="2011-01-11" version="1">MANIIPLNFRVAKPEDAPKIQQLVQAAFRAEDSRADWTADMELGRSFQYSVEEVLKTINNPDAAIIMASDENGVLLGSIGIIKCNDNLARFAMLSVDPEQQCGGIGRRVLAYAEDFARNWNLRTFGLNALSSREKLIAWYERCGYKKSGETSPFPVDQLPQLNLPKDLCFVELEKDTLAEELVVRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QI91</accession>
    <name>E3QI91_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05850</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094726.1">
        <property type="nucleotide sequence ID" value="XM_008096535.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QI91"/>
    <dbReference type="STRING" id="645133.E3QI91"/>
    <dbReference type="GeneID" id="24411215"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05850"/>
    <dbReference type="eggNOG" id="ENOG502QTVK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033074_2_0_1"/>
    <dbReference type="OrthoDB" id="5317787at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="473" mass="53751" checksum="6B6CE9EF0457E14A" modified="2011-01-11" version="1">MSDSYRKNSSKSSTCSRGSRRSNESCDSFETYESQSTTPTSYYASTEASVKEARAVSHKFQPVYEEDVSPSTSNCLRSSVDTFDSSLASDDEDELELMRDIEMDDFDPYQEIPPLPAYCRDIIETDVRPSNPQDFAKLFPSMNRLSISHDEFTPDGNMNLRVDTVVPGRRPHNIQLFHLRMHDLAKREFSLRRYCRDSGREVCNSKRKYVEEAIEQRPTLQRSVSSAIKTLSMRRPLPRTNSGGSFLAGKGKDVTSQRPQSSASSSRNSTDDTASYFRRSASFEPKPKARRIPSNTMKLEFSNYARVDVSRRGGTNNKRYEFEWWGHKYQWKRVLDKNLGAVSFHLVKDGNNNARDAVAHIVPETRSPNQVVEDESAGGWVPPCHMWISDRSVLDAVTDVADVIVATGLVALVDDCIKHRWQTKKIHHIPVPLTSRTVNVEYVGPRAFLQQLFLRRASDHTSGPLRQRSIATY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QII2</accession>
    <name>E3QII2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Spliceosomal protein DIB1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_05736</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the DIM1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094612.1">
        <property type="nucleotide sequence ID" value="XM_008096421.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QII2"/>
    <dbReference type="STRING" id="645133.E3QII2"/>
    <dbReference type="GeneID" id="24411101"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05736"/>
    <dbReference type="eggNOG" id="KOG3414">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_117348_0_0_1"/>
    <dbReference type="OrthoDB" id="147752at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02954">
        <property type="entry name" value="DIM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000004">
        <property type="entry name" value="Spliceosomal protein DIB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004123">
        <property type="entry name" value="Dim1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12052:SF5">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12052">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEN 4A, 4B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02966">
        <property type="entry name" value="DIM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017199">
        <property type="entry name" value="mRNA_splic_U5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01410">
        <property type="entry name" value="DIM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4 6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="39"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR017199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR017199-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ30592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="143" mass="16809" checksum="07539638ABE9177D" modified="2011-01-11" version="1">MGSIVIPHLNSGWHVDQAILSEEERLVVIRFGRDADPQCMQQDEVLYRISERVKNFAVIYVCDIDLVPDFNQMYELYDPCTIMFFFRNKHMMVDFGTGNNNKLNWVLEDKQELIDIIETVYRGAKKGRGLVVSPKDYSTRHRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIW6</accession>
    <name>E3QIW6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Elongation of fatty acids protein</fullName>
            <ecNumber evidence="12">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_05948</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a very-long-chain acyl-CoA + malonyl-CoA + H(+) = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:32727"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:90725"/>
            <dbReference type="ChEBI" id="CHEBI:90736"/>
            <dbReference type="EC" id="2.3.1.199"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>an acyl-CoA + malonyl-CoA + H(+) = a 3-oxoacyl-CoA + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:50252"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:50253"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the ELO family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="12"/>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094824.1">
        <property type="nucleotide sequence ID" value="XM_008096633.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIW6"/>
    <dbReference type="STRING" id="645133.E3QIW6"/>
    <dbReference type="GeneID" id="24411313"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05948"/>
    <dbReference type="eggNOG" id="KOG3071">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048483_6_1_1"/>
    <dbReference type="OrthoDB" id="434092at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009922">
        <property type="term" value="F:fatty acid elongase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034625">
        <property type="term" value="P:fatty acid elongation, monounsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034626">
        <property type="term" value="P:fatty acid elongation, polyunsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019367">
        <property type="term" value="P:fatty acid elongation, saturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002076">
        <property type="entry name" value="ELO_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157:SF134">
        <property type="entry name" value="ELONGATION OF FATTY ACIDS PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157">
        <property type="entry name" value="FATTY ACID ACYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01151">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6 12" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="3 12" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8 12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="94"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="229"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="267"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ30804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="327" mass="37035" checksum="0A45CA611936A74A" modified="2011-01-11" version="1">MLNDNFTTGNTTFPLTMERQVSASLFSPWKTFDKVFTSVMGYPAKEFEFVPGHTPFSTLGGAVGMAVLYLVVIFGGREVMRNRKPVELNTLFKIHNLFLSLLSGALLVLFIEQLVPSLWRGGLYENICGVSGWTQPLVLLYYINYLTKYYELIDTVFLMVKKKPLTFLHCYHHPATALLCFSQMIGGTPLSWVPITLNLTVHVVMYWYYFQTARGVKVWWKQWITRLQIAQFVLDLGFVYFGFYDVFADTYFKDILPHVGRCGGEFFAAVTGGAILTSYLVLFIMFYISTYKKGGQRGAQKTKSAVLSEKRSFAAGPANGARAEMKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJF1</accession>
    <name>E3QJF1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">GRAM domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_06133</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YSP2 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ30989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095009.1">
        <property type="nucleotide sequence ID" value="XM_008096818.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJF1"/>
    <dbReference type="STRING" id="645133.E3QJF1"/>
    <dbReference type="GeneID" id="24411498"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06133"/>
    <dbReference type="eggNOG" id="KOG1032">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006864_0_0_1"/>
    <dbReference type="OrthoDB" id="2162691at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032541">
        <property type="term" value="C:cortical endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140268">
        <property type="term" value="C:endoplasmic reticulum-plasma membrane contact site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120015">
        <property type="term" value="F:sterol transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032366">
        <property type="term" value="P:intracellular sterol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13220">
        <property type="entry name" value="PH-GRAM_GRAMDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051482">
        <property type="entry name" value="Cholesterol_transport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004182">
        <property type="entry name" value="GRAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031968">
        <property type="entry name" value="VASt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23319">
        <property type="entry name" value="GRAM DOMAIN CONTAINING 1B, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23319:SF4">
        <property type="entry name" value="GRAM DOMAIN CONTAINING 1B, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02893">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16016">
        <property type="entry name" value="VASt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00568">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51778">
        <property type="entry name" value="VAST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1142"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="domain" description="VASt" evidence="8">
        <location>
            <begin position="902"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="160"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="456"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="523"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="781"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1072"/>
            <end position="1115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="71"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="84"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="98"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="130"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="179"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="254"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="270"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="292"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="323"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="343"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="365"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="375"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="423"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="478"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="547"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="788"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="798"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1085"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1105"/>
            <end position="1115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ30989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1262" mass="134735" checksum="E2CFE91F63366517" modified="2011-01-11" version="1">MDAASESGGGLSKLLPKAIVAKRRRRKQEAREDDAAAATAAMLLGVKGEDVTAPADTPAPLRGDSVSYMSARRDSGSYVHDTDSFSNKDSSTGFPDYDYDHYREHGHDAVDETSTEATTSMVTLAESEVEQSSPRPNAISTHPSQIGYLTTSSPIVQATHLPEPQPQILDGQLPEIASARSTANNSAKRTQSVESTDSSLRSQRSFTSLVPPKKNITRSPSPVGRLKGVFSKSKKTPSAATSPERSVGSDDTTDDGRDTRRTRDRGRAFASASTSDLISSSTVLTKKPSLDRPSTPQPNTTDDAGAPRVKSTSHSPERRRSRASTTTSRIDTSFVPQTPPNPDTNTPVIVNTPPTPTDHSAPFTQSPPGPPPKPTIEAPTASGNTNGGSSTGNMIAHRRGRSGSGSIGPSKLSKITLAPLTPTPENSTPGNPGTPSGAGFFSSVFSAAQNAATSLSSTIQNTGIGPPPSKNKNITKPPDIKIDREPEVEPPPPSTTGSTMDKEPAVKTIGSGELSLSQLGITDTGSASGTPITAKFPESAEARVRSDSAPTDAAYAAATRDLGVDDGRQVTRPQSLYEPGSGGDRTPPQGSIHEDRISGVQRSGSIRSAIGRHRKRGSSAVSGGTATTIGAAIAAANASVAHPQANASVPKLTGFAVASKKRNRDFHALFKSVPDDDYLIEDYSCALQREILAHGRLYVSEGHLCFSSNILGWSTTLVMSFDEIVSVEKRSTALVFKNGLMISTLHAKHIFASFTSRDSTYDLIVNIWKLGHPTLRSSLNGVQLEGTGGDKTEKVDGDDAVVAEIDDGSLSGTDEDSESGDDDDVYDEDDDADDLQDVTQLSEVNAEPDGGKTVSRKVSGAGANSAVADVVKDAVGVPSGGDDFPGPAAHAPTDCGDADTHYERIVGDDVIPAPLGKVYNLLFGPASVTWMTKWLTVEAKCTELQMEDKKGLTLENRSRYFTYIKPLNGAIGPKQTKCLVTETLDNLDFEKAINFSITTQTPDVPSGNIFSVKTKYCLTWAENNSTRVQSNCTIEWTGKSWLKGPIEKGANDGQIQYCKDLFASLKSAVSSKARSGGTGAGPGQKGKKKGKKSKAAGSSTDAEDEQVRLKNTPKKDWGPLEPVRGILEPILDIAKPLMAGNMMYGLLVGLLIATWFGFGLPGRQPSGDMRMYGYPDRLAAYDEMWRREESELWEWLEERVGLERLHGGQLPTRKRAIEPSTVEERVREDRMGEREIEEAIRVTEEKLKVLKDVMDKKKPLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJG0</accession>
    <name>E3QJG0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Homoserine O-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_06142</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. MetX family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ30998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095018.1">
        <property type="nucleotide sequence ID" value="XM_008096827.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJG0"/>
    <dbReference type="STRING" id="645133.E3QJG0"/>
    <dbReference type="GeneID" id="24411507"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06142"/>
    <dbReference type="eggNOG" id="ENOG502QRIX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028760_5_0_1"/>
    <dbReference type="OrthoDB" id="191364at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004414">
        <property type="term" value="F:homoserine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071266">
        <property type="term" value="P:'de novo' L-methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009092">
        <property type="term" value="P:homoserine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00296">
        <property type="entry name" value="MetX_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008220">
        <property type="entry name" value="HAT_MetX-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01392">
        <property type="entry name" value="homoserO_Ac_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268">
        <property type="entry name" value="HOMOSERINE O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268:SF11">
        <property type="entry name" value="HOMOSERINE O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000443">
        <property type="entry name" value="Homoser_Ac_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="5">
        <location>
            <begin position="62"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="244"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="253"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="271"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="289"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="398"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000443-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ30998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="485" mass="53267" checksum="70282AF8B3C7B42D" modified="2011-01-11" version="1">MALSRSMVKRTQTQPENPFATLIPEQQFAIIPEFSLESGVTLRNVPVAYTTRGKLSPNGDNAMVICHALTGSADVSDWWGPLLGGPGRAFDTSRFFIVCMNALGSPYGTASPVTAKDGDPSKGNYGPEFPLTTIRDDVNLHKLLLDDLGVKQVAAVIGGSLGGMFVLEWAYLGKEYIRCIVPIATSSRHSAWGISWGEAQRQSIYADPKYDDGYYPFDDPPSTGLGAARMSALLTYRSRNSFESRFGRNIPDPSRRQTIRERSRPSTPSEAHFHIHNDGHNVKRAGLPRQNSQGGTGETSVNSTLAQAATEALDPQFHGPQTESLAGGDNIPTSTYFSAQSYLRYQGQKFVKRFDSNCYIAMTRKLDTHDVSRGRASTIAEALALIEQPTLVLGIESDGLFTFAEQEEIAEHVKNAKLERIDSPEGHDAFLLQFEQVNRYVLGFLKQTLPDIMEKKGEEVEETGVGQLTKSSTFGEAEVEDITAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJV6</accession>
    <name>E3QJV6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="17">R3H domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">GLRG_06288</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Regulates global gene expression after oxidative stress. Interacts and stabilizes mRNAs and may regulate their transition between different cytoplasmic components after oxidative stress.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Interacts with csx1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697353">
        <property type="protein sequence ID" value="EFQ31144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095164.1">
        <property type="nucleotide sequence ID" value="XM_008096973.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJV6"/>
    <dbReference type="STRING" id="645133.E3QJV6"/>
    <dbReference type="GeneID" id="24411653"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06288"/>
    <dbReference type="eggNOG" id="KOG0108">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022096_2_0_1"/>
    <dbReference type="OrthoDB" id="434258at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12253">
        <property type="entry name" value="RRM_PIN4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.50:FF:000002">
        <property type="entry name" value="Immunoglobulin mu DNA-binding protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000183">
        <property type="entry name" value="R3H domain containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.50">
        <property type="entry name" value="R3H-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034186">
        <property type="entry name" value="PIN4-like_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001374">
        <property type="entry name" value="R3H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036867">
        <property type="entry name" value="R3H_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003:SF17">
        <property type="entry name" value="RNA-BINDING PROTEIN PIN4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01424">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82708">
        <property type="entry name" value="R3H domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51061">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="15">
        <location>
            <begin position="163"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="R3H" evidence="16">
        <location>
            <begin position="299"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="246"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="464"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="521"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="12"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="272"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="480"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="493"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="549"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00055199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00062407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EFQ31144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="580" mass="62879" checksum="1C2FF0FC1438DD99" modified="2011-01-11" version="1">MSQQQHDMYLDYSAPPNRSPSSSRAYAGGFQSGMSLPRQAQRPYDNGLGSSALFPSDRLGYNPRAMDQMSANGMPGGYMLDNSQTWNYNAGGVATVSGAMNGANRQRSVNRRAALPTNWTDQGLGMHGSYGSSINGGMSNGLRYDGQGDMRPSSQTEEQLIPTAIVIKNIPFAVRKETLAAVMLEMHLPQPYAFNYHFDNGVFRGLAFANFQSPEDTKIVIDAMNGMEVHGRKLRVEYKKMLPEAERERIEREKRERRGQLEEQHRAPMLHQQPSLQTLNSVSSNPPRGPLDGDIDLNDPETLEFYTELTLFKRDTSREILIFPSTIAPEQRRRIHILAHHMGLEHSSVGEAESRQIHVVKRQLPSPTAQIHSPAVGLDYHKKGLSRAATFDFAADREARSASTNYSHAIGRQGPTLELPGSPDGNGLANLRAAKSFADLRSFSPSPSASSSGYLTAMNGIGNIPQSGNSNPRFGDYNGGVNQSGQLATPNLTPTSGTVGTPGTDSSLLSSLGGLNLGSYESAAHSQARSTPGAIGSQRPGANSGNRNAPERQPRGPEWETSAGFNGRNRSNGHMQRGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJZ6</accession>
    <name>E3QJZ6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Guanylate kinase</fullName>
            <ecNumber evidence="2">2.7.4.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">GMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_06328</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the guanylate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.8" evidence="2"/>
    <dbReference type="EMBL" id="GG697353">
        <property type="protein sequence ID" value="EFQ31184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095204.1">
        <property type="nucleotide sequence ID" value="XM_008097013.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJZ6"/>
    <dbReference type="STRING" id="645133.E3QJZ6"/>
    <dbReference type="GeneID" id="24411693"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06328"/>
    <dbReference type="eggNOG" id="KOG0707">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001715_0_4_1"/>
    <dbReference type="OrthoDB" id="6334211at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004385">
        <property type="term" value="F:GMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00071">
        <property type="entry name" value="GMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000776">
        <property type="entry name" value="Guanylate kinase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00328">
        <property type="entry name" value="Guanylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008145">
        <property type="entry name" value="GK/Ca_channel_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008144">
        <property type="entry name" value="Guanylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017665">
        <property type="entry name" value="Guanylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020590">
        <property type="entry name" value="Guanylate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03263">
        <property type="entry name" value="guanyl_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23117:SF13">
        <property type="entry name" value="GUANYLATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23117">
        <property type="entry name" value="GUANYLATE KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00625">
        <property type="entry name" value="Guanylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00072">
        <property type="entry name" value="GuKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00856">
        <property type="entry name" value="GUANYLATE_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50052">
        <property type="entry name" value="GUANYLATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Guanylate kinase-like" evidence="9">
        <location>
            <begin position="9"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ31184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="194" mass="21610" checksum="4EF05C616862274E" modified="2011-01-11" version="1">MAPVLPSDRRPIVISGPSGVGKGTLYKLLFERHPDTFALSVSHTTRGARPGEQDGVDYHFVTREAFDDLVARDGFVEHAVFGSNAYGTSKATIEEQSAKGKLVVLDIEMEGVKQIKQSNFPARYIFIAPPSEEELEKRLRGRGTEKEESIQKRLAQAKLELEFSKTPGVHDIIIVNDDLEKAYKALEDFVYKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QK65</accession>
    <name>E3QK65_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_06397</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697354">
        <property type="protein sequence ID" value="EFQ31253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095273.1">
        <property type="nucleotide sequence ID" value="XM_008097082.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QK65"/>
    <dbReference type="GeneID" id="24411762"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06397"/>
    <dbReference type="eggNOG" id="ENOG502RAGH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061206_0_0_1"/>
    <dbReference type="OrthoDB" id="3473305at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910:SF1">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="43"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="361" mass="40315" checksum="561912BEAEF2C26F" modified="2011-01-11" version="1">MATELQLQAISLLEKIAQSQRVLEKRLDAIERLIGRQGPAPYFPQFRRLPPELRHRIWSLAIPTRVLRLSRRASKKHATLLVSPPAIAGACREARAVATRNGGIVYLKHDTANPESPIRTTQYWFDSCHDVLELDRRFDVAGDEPRGSRDLVRDAQHILAPRAEAEWFARLFRQTAHLRRLSLMFDAVSVSPCVWDTGVVRRLFGDAGTVVTMDLENAGEIAWVKGVLREHWRNPVFCAFDLEAWARERGFGVGTGPRDEGWMRRLPGTWMSEVARGWVMAKAEELAAEIGGEAGGRVEGGTRGQLETEASEARTRASAATAAAATLDMKDDFVRAALLAMPRVELVRVFSHDEVHAGCRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QL27</accession>
    <name>E3QL27_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_06854</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697356">
        <property type="protein sequence ID" value="EFQ31565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095585.1">
        <property type="nucleotide sequence ID" value="XM_008097394.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QL27"/>
    <dbReference type="GeneID" id="24412219"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06854"/>
    <dbReference type="eggNOG" id="ENOG502T4HM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_783052_0_0_1"/>
    <dbReference type="OrthoDB" id="4712560at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="140"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="336"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="354" mass="40454" checksum="913740FB04B69F94" modified="2011-01-11" version="1">MECPNDELELAKRRLGFQIQILRDEMERQFKRILTQTVEAHENDRKNNFERYLTRASLECPPGIFERLKSWIRGEFPSYISAFHYSQGGSYSINFTNTPPPGAWEPIVVDMNKIFDQIAPTATDAQKDMAALKGVHPSENTPTTPSRRPLPTNRRTSPRIKTPCPKKTDKLPTARVEKSKPSNRSLPQTPRKQKRPVGEGSQPVGGGVIKTAVATKTISENPSWAFSYDLGEGFQYYILRCPTPGCQFSFSLNPLKNNMAVSHFEECKVPYLDETDIVRRYARQLQKQRMDKDPSGEVSKMWIDNYNQQVARERKRRRRKEPKSAFESPKIHVVDGSSTESPETSPGDTEIMQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMX1</accession>
    <name>E3QMX1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">VTC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_07353</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697360">
        <property type="protein sequence ID" value="EFQ32209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096229.1">
        <property type="nucleotide sequence ID" value="XM_008098038.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMX1"/>
    <dbReference type="STRING" id="645133.E3QMX1"/>
    <dbReference type="GeneID" id="24412718"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07353"/>
    <dbReference type="eggNOG" id="KOG1161">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG4580">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009308_2_0_1"/>
    <dbReference type="OrthoDB" id="6493944at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033254">
        <property type="term" value="C:vacuolar transporter chaperone complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006799">
        <property type="term" value="P:polyphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd14480">
        <property type="entry name" value="SPX_VTC2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.100.30:FF:000002">
        <property type="entry name" value="Vacuolar transporter chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.100.30">
        <property type="entry name" value="VTC, catalytic tunnel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003807">
        <property type="entry name" value="DUF202"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051572">
        <property type="entry name" value="VTC_Complex_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018966">
        <property type="entry name" value="VTC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042267">
        <property type="entry name" value="VTC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140:SF2">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE 3 COMPLEX SUBUNIT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02656">
        <property type="entry name" value="DUF202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09359">
        <property type="entry name" value="VTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="680"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="722"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="domain" description="SPX" evidence="8">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="565"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="580"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ32209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="772" mass="88589" checksum="C38C90273E78C221" modified="2011-01-11" version="1">MRFGKTLRQAVYAPWKDKYIDYAKLKSLLREDKYDEDDVAWTENDESRFCDEIFNGQLEKVAKFQEETFETLKRRIDAAFEKLKELAPPPSEEEDGAENAQVKKPDAATAAKLKDIETELDKITTEISELKKYSNINYTGFLKIVKKHDRKRGDRYKVRPMMQLSLSQRPFNSEQSYSPLLNKLSIMYYAIRQQLDDGATDQQPLDLESQGETRRGERYTAHKFWVHPDNLLEVKTYIMRQLPALVYSEQSAKELDGSNDPTITSLYFDSPKFDLYSKKVERKSEASSLRVRWYGQLSSKPELYFEQKIVGENGSSEERKFAIKDKYIKPFIDGTYKMEKTVQKMERQGQQAEDIENFKSTVESLQGFVQENKLEPVLRANYVRTAFQKPADDRVRISIDTEVAFIREDTLDKSRPCRDPADWHRFDIDGRNLTYPFKDINQSEVSRFPYAILEIKLKEDSSRKRPEWISDLMGSHLVHPAPRFSKFVHGVASLFEDYVNNLPFWLTDLEADIRKDPQEAFEAEEQRKAQRAEDEQAVGSFLGTKISSYKVSKSSPAGKSYLADRMAAEPSSRPKPSERQSQQNGNGSSDQQPRSYGTLSSVLPGFSLSKYSKAKRAQKNQQQLPEGVVEPTEWIKNSGELKIEPKVWLANERTFLKWQHICILLGALAVSLYTAAGENFLAEVMGIVYIVIAVFAGVWGYGMMRLRRKMIIARSGKDFDNLIGPLIISIALMVALVLNFVFAYRAAVEKMESNDVLGGGNVTGEPFRQELI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNB1</accession>
    <name>E3QNB1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cytochrome b-c1 complex subunit 8</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Complex III subunit 8</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_07493</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The complex plays an important role in the uptake of multiple carbon sources present in different host niches.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with cytochrome c oxidase (complex IV, CIV).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Mitochondrion inner membrane</location>
            <topology evidence="1 11">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the UQCRQ/QCR8 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697361">
        <property type="protein sequence ID" value="EFQ32349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096369.1">
        <property type="nucleotide sequence ID" value="XM_008098178.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNB1"/>
    <dbReference type="STRING" id="645133.E3QNB1"/>
    <dbReference type="GeneID" id="24412858"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07493"/>
    <dbReference type="eggNOG" id="KOG4116">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_156007_0_1_1"/>
    <dbReference type="OrthoDB" id="6683853at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045275">
        <property type="term" value="C:respiratory chain complex III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.210:FF:000001">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.210">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004205">
        <property type="entry name" value="Cyt_bc1_su8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036642">
        <property type="entry name" value="Cyt_bc1_su8_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12119:SF2">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12119">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX UBIQUINONE-BINDING PROTEIN QP-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02939">
        <property type="entry name" value="UcrQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81508">
        <property type="entry name" value="Ubiquinone-binding protein QP-C of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ32349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="105" mass="12059" checksum="DE8BF9CAE45F016D" modified="2011-01-11" version="1">MRPTQALMSGPSVPHGKYQHYLGWWGHIGGEKQRGIITYGIAPNRQNPFAGAAHDAVFNTWRRFSAQVLYFLPPLVAGWYIMDWATHRNHYLNSKQGRAEFSDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNC3</accession>
    <name>E3QNC3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_07505</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697361">
        <property type="protein sequence ID" value="EFQ32361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096381.1">
        <property type="nucleotide sequence ID" value="XM_008098190.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNC3"/>
    <dbReference type="STRING" id="645133.E3QNC3"/>
    <dbReference type="GeneID" id="24412870"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07505"/>
    <dbReference type="eggNOG" id="ENOG502T53B">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_12_3_1"/>
    <dbReference type="OrthoDB" id="4682787at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF108">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="108"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="144"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="194"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="49"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="363"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="377"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ32361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="388" mass="43055" checksum="4D269AD566776206" modified="2011-01-11" version="1">MADGSGLVGALPPPPGIVPDFYHPTDLSRTRLFAAIVVMAVAITIPFIFRIYSKTRITVEYYKEDWTCTVAYVMLMCYLGTVLVMAYYGEGYHAWEVTKKDYSKINLFLYIGSIIYCPAAYFTKVTLLLFEARVFSVYQRVAKTIHVFIVALAILYMPILFTKAFLCTPVAAAWNLDIKPAKCLNQRKVFLSDMSLGLLTDICILVLPLLLTRPLHVSLRTKIKIVMLLGAGGAATGVSALRLYKEVECLGTTDATEGYFLLNLTTWFTVQRHSTPNVPRTCRHDNARKAWYSKMWSRKTATTLMDLDSQGESNSNESAIAPDPEAVLQSDMGSNCGHITGVSGGGGPYESLLEPPSGIKVPEEALTRNYTGVNGNRVRETERERTVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNC7</accession>
    <name>E3QNC7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PrpF protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_07509</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PrpF family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697361">
        <property type="protein sequence ID" value="EFQ32365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096385.1">
        <property type="nucleotide sequence ID" value="XM_008098194.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNC7"/>
    <dbReference type="STRING" id="645133.E3QNC7"/>
    <dbReference type="GeneID" id="24412874"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07509"/>
    <dbReference type="eggNOG" id="ENOG502SIH5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026443_0_1_1"/>
    <dbReference type="OrthoDB" id="10267539at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.10">
        <property type="entry name" value="Diaminopimelate Epimerase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007400">
        <property type="entry name" value="PrpF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43709">
        <property type="entry name" value="ACONITATE ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43709:SF2">
        <property type="entry name" value="DUF453 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G00360)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04303">
        <property type="entry name" value="PrpF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54506">
        <property type="entry name" value="Diaminopimelate epimerase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="337"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ32365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="411" mass="43053" checksum="F65832DD21701FCF" modified="2011-01-11" version="1">MAITPSTSKRRVRHSLPAVMMRAGTSKGLFIHQSHLPPSQDEWATPLLAAMGSRNNDARQIDGVGGGSSVTSKVAVVAPSERPGVDVEYTFVQVAVGSENVDLTGNCGNMCSGVGPFAVQERLVTPAPGAQSVDVRIFNTNTSKLIVETVHVDEDGNVEEDGDCTIPGVKGSGSEIKVAFVDPVGSMTGKLFPSGQRSEKIVVEGVLASGDFVVDVTLIDSANPFVFVDAESLPASVREQPADSPLALEVAEAIRRQGAVRMGLASSVEAAGLVRGTPKLAYLSRPSNGETGKEAADIQVLAYSMGKPHPSFQLTGGVTLASAVTSEGTVAHRIAGGSESALSAEGLPTPRRTPPPADEHNQGRTVRIKHGSGVMDVEVKTRESEDGVAVDRCIVTRTARRLFEGNVLYYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNE6</accession>
    <name>E3QNE6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07528</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697361">
        <property type="protein sequence ID" value="EFQ32384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096404.1">
        <property type="nucleotide sequence ID" value="XM_008098213.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNE6"/>
    <dbReference type="GeneID" id="24412893"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07528"/>
    <dbReference type="eggNOG" id="ENOG502R962">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1594399_0_0_1"/>
    <dbReference type="OrthoDB" id="4831063at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180744" evidence="1">
        <location>
            <begin position="30"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="167" mass="19012" checksum="D1994B7DCE04ECB5" modified="2011-01-11" version="1">MRIPGLHPLTASLITSVLTLFSLTKMTASVPTHILHLVDDTVKPEHQSLTSAVQVPGIHPPQKRDERNCISVYLCTEKDWTGDCYWACYRRGLEVQLETEWASKIKSVRPDHDTKCKFFFGTECRTRHQSQDMVYPGGNFDAKKMGKLSTLGFNNKQHMMIKVVFVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPC1</accession>
    <name>E3QPC1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07853</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697364">
        <property type="protein sequence ID" value="EFQ32709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096729.1">
        <property type="nucleotide sequence ID" value="XM_008098538.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPC1"/>
    <dbReference type="STRING" id="645133.E3QPC1"/>
    <dbReference type="GeneID" id="24413218"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07853"/>
    <dbReference type="eggNOG" id="ENOG502QQM5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1229838_0_0_1"/>
    <dbReference type="OrthoDB" id="1179585at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="225" mass="24107" checksum="7B672502D36E6043" modified="2011-01-11" version="1">MYGGLVSNGVTVPSQAEPFLARVNIRMWIIGNGAWNGAGTRPAVGREATLQRPRSRRERRRPLNELQYGTAHTKLRLGLLSTGDHIGTHEGTPYVDVKFAPADGDLHLSHSSGGDSPTPTAPDPTLSPGAAAAIACPDRPTVCRVQTHRCGIYAVSFYIDALLPDQAVPPRRTWSSRQLGVLGPARAVSPSPTGNRSGTPRTGAAFELRLVQFLVSVVLFRQGEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPJ6</accession>
    <name>E3QPJ6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_08045</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697365">
        <property type="protein sequence ID" value="EFQ32901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096921.1">
        <property type="nucleotide sequence ID" value="XM_008098730.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPJ6"/>
    <dbReference type="STRING" id="645133.E3QPJ6"/>
    <dbReference type="GeneID" id="24413410"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08045"/>
    <dbReference type="eggNOG" id="ENOG502SQ5K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099507_1_0_1"/>
    <dbReference type="OrthoDB" id="5232980at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ32901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="188" mass="21347" checksum="33EC86B377A072A9" modified="2011-01-11" version="1">MRTICPKYISVKEAGLICNQFLSSLELDRQVLWSGMEREKAQKWADTHQRQTLTTALGPLRALEKSKGRKARSKFMKGASAIFSWFISQGDRVVILLPPPPNQFHPSGLTSLQDFEIPIIQGLLRDGSVKRIDVIHPDATSEEARNSSHQLWPCDETKSWIDRFGVGRKSRAWRAVKSGIGMLKYDHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPK8</accession>
    <name>E3QPK8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07929</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697365">
        <property type="protein sequence ID" value="EFQ32785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096805.1">
        <property type="nucleotide sequence ID" value="XM_008098614.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPK8"/>
    <dbReference type="STRING" id="645133.E3QPK8"/>
    <dbReference type="GeneID" id="24413294"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07929"/>
    <dbReference type="eggNOG" id="ENOG502QTKU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028866_0_0_1"/>
    <dbReference type="OrthoDB" id="64915at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006740">
        <property type="term" value="P:NADPH regeneration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000911">
        <property type="entry name" value="Chromosome 8, whole genome shotgun sequence"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840:SF7">
        <property type="entry name" value="BINDING ROSSMANN FOLD OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G10190)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="1">
        <location>
            <begin position="10"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="375" mass="41882" checksum="9487CE846A72997A" modified="2011-01-11" version="1">MASQQKTRVLRVGIIGCGEITQVNHISNLNFLYERFQTTYLCDISHQSLAHCARKVQGGTPKTTTDAAELCSSPDVDVVVIANTDAYHVDHGILALKSDKYVLIEKPVSVCFRDIDLLIEAERNSKGKVMVGTMRRFATVFTDAVEEVGGMDKIQYARVRDIIGPNSTFVGQSGTFPIKFSDYSDVDTQERLKREEDISEQAIGREFGVPVTSESQRMLRLLGGLGTHDLSAMREIIGMPKSVAGAVLTFPGIFSVLFNYDDFPVTYESGINNVPQFDAHIEVYSPNKIVRVNFDTPYVKGLPVTMTIRELVGEDGFQERTVRKTYQDPYTNEFLEFYDCVVNGKTPKTSTTDARNDIELFKMILRADAGRYSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPT4</accession>
    <name>E3QPT4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Carbonyl reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_08005</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697365">
        <property type="protein sequence ID" value="EFQ32861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096881.1">
        <property type="nucleotide sequence ID" value="XM_008098690.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPT4"/>
    <dbReference type="STRING" id="645133.E3QPT4"/>
    <dbReference type="GeneID" id="24413370"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08005"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_9_0_1"/>
    <dbReference type="OrthoDB" id="1933717at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43963">
        <property type="entry name" value="CARBONYL REDUCTASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43963:SF6">
        <property type="entry name" value="CHAIN DEHYDROGENASE FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G15350)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ32861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="288" mass="30987" checksum="31F21B64101A6260" modified="2011-01-11" version="1">MAYSRIGVVTGANKGIGYAIVRQLALQYPKSPLNNGPLLIYLTARDKSRGEQAVSNIQGDADLKQTKALSAHGGATAIKFHQLDISDCGSISKLASFLKKEHPDGIDFVINNAGIAMQGFDSNVVKNTLACNYYGTLEATRAWIPILKPDGRIVNVASISGSLSKYSPEIRQRFYNTQSVSDVTKLMEEFTAAVEKGTHEKDGWLSAAYAVSKAGEIAMTRAIARELQEKGSKLMVNSCHPGYVVTDMTKGGGTKTPDQGAQTPVHLAIADIGGTTGEYWSDEKIAKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPU9</accession>
    <name>E3QPU9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_08020</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. Epoxide hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697365">
        <property type="protein sequence ID" value="EFQ32876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096896.1">
        <property type="nucleotide sequence ID" value="XM_008098705.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPU9"/>
    <dbReference type="STRING" id="645133.E3QPU9"/>
    <dbReference type="GeneID" id="24413385"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08020"/>
    <dbReference type="eggNOG" id="KOG4178">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_7_4_1"/>
    <dbReference type="OrthoDB" id="408373at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43329">
        <property type="entry name" value="EPOXIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="49"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ32876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="387" mass="42651" checksum="961FB63CC7C92734" modified="2011-01-11" version="1">MDPAQLPSWDLPEGVISRYVDTSPVGLKFHILESFPDAVSPSRLPPLALLLHGFPNLSHDWRFVMPKLAEAGYYAVALDMRGFGRTHNADLSPISENSFRLMTALRDVVTLVHALGYETVHALVGHDIGAFVASLCAVVRGDMIKSLVLMSHPFKVSPQLPFGTAVSPLLVSAASKGAGPNKADPGIRSSLLKLDPPRKHYKYYNASPEAAEEWTNPTGEPMRRFLRGHFHLKSAAYSLNRPRPLASWTAEQLAVMPHYYVMRAELSMRGNVELDMSDEPAEIRDRLGETRWLTDADLQVYTDKFSRNTFGPPLLWYKVLVDTSLSADLLCFAGTKIGVPTKYVSGTSDWGTYQVPGSLDAMENGEGVNKEKPEESVKEILALASSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQF7</accession>
    <name>E3QQF7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08239</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697367">
        <property type="protein sequence ID" value="EFQ33095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097115.1">
        <property type="nucleotide sequence ID" value="XM_008098924.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQF7"/>
    <dbReference type="STRING" id="645133.E3QQF7"/>
    <dbReference type="GeneID" id="24413604"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08239"/>
    <dbReference type="eggNOG" id="ENOG502SSBS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023254_1_0_1"/>
    <dbReference type="OrthoDB" id="4158087at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540">
        <property type="entry name" value="TRANSCRIPTION FACTOR (ACR-2), PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540:SF5">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ33095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="503" mass="56784" checksum="FFC1B39AF786E7A4" modified="2011-01-11" version="1">MGTQKHPGMAPSRPAETLASNVIIVANKGFAFVITDTSGKPNSEDRKLIRSHVMRGKNRRASLGNTKPPSVRVTGKASDPSRERSQVYHVPNDIYMVQFAQEVDAASRAMLFEFYGAIKETMYPVEWCLRFDDSKTPWFYWLFSDAAFMHSILFTVCLLHDSIRGETSKRTSFHVWKALNLLNRNISDESLALADSTIATVVSMCMVSEVFGHRDSAAAHVRGMRRIVQLRGGIERFRHNLQLHVKICRVDIGWSLCTGEKPLYYRDNISWESAFASMLGNPPTGFEHDRHLSDVRLFVDSTDRRIGNVFQDLHDFSRLANFLVKTGRKIDPNGFQNLMISIQYRLLHLNPIEQSSVSEMFRLGMISFITTLFLKVQGAKIELTFLAGQFRSACQNLDVSELSTTTVRLMFAWALVVGAISVFDGSDDLWLLPKLASLRDSLGPTWPEAKASLEQVMWMDMVHSPTGVKVFQKLVLHVAQIPLEGPLLNRRSSTTVVNFKTYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQI0</accession>
    <name>E3QQI0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_08262</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697367">
        <property type="protein sequence ID" value="EFQ33118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097138.1">
        <property type="nucleotide sequence ID" value="XM_008098947.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQI0"/>
    <dbReference type="STRING" id="645133.E3QQI0"/>
    <dbReference type="GeneID" id="24413627"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08262"/>
    <dbReference type="eggNOG" id="ENOG502S1W1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006713_0_0_1"/>
    <dbReference type="OrthoDB" id="2423701at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027974">
        <property type="entry name" value="DUF4470"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14737">
        <property type="entry name" value="DUF4470"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="10"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="44"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4470" evidence="2">
        <location>
            <begin position="163"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ33118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="890" mass="100484" checksum="ACC2A20713081E33" modified="2011-01-11" version="1">MPSPNELQESTAARERGNGFYRRGLFAEAEKAYREAASLAPKDPAPWSNISAIKFEQGDYSTALDNIEKALSLSAEEPDSSPKKQKLYTRMAKCHLFSLSFDDAEKSVTSLHDDSSAHAMRATLEDMHKISSMSSKGELRQQVLDRLPLYKGQLQDRPEYYAVGHDTAYPLWDEPLWHAVGPRGDVSFLLCGSGDARHLFATMVFLGLSGLSQGENRLFNKAHFTILDINATALARTLVILDMVIRYAIMRCAKMPRIEDALTVMSYIYSSAVVPAFVAEKLEEHVKSVIDELEGEGDVLEIFFIPRDTRNKIIKKLKQWIQPLADDYALKNLRPATALKDSTKEFRELGVLFAGDVFIGRREPALRPLLDAFRSNVQGAKQILEGYIDSHWKTNPTLLDMDYEARRDDVLDTSAPPRKFTPSIELDPAQLMQSIYNPARPKPEDGDVLESLDGFFETLATATMTLLQHVQIEAIAGEMADTLERIRYDGFGHRSQKPLKVGAIDATKFPRQYDRIHMSNIPDYVGGPLAALLYGGPLLREDRPSNLRFNNLLNPPMFETHDQFLTEYILMYDAKQVADHFGLVKEKETGGVISNPIAKMIGNQFMTEDYFIWSRSGSKKTPLSRLMTRPALEKWLHSHLLKICIPYPRPLWSDSPVHAPLNLTAFFRIVVRLHEVGYPAHWLADVLASICEGSITTTARSPRKLVLHPNDLKTSYQQRKISLSPWKAEFTTLLSLWRRLLPFGIVTPPSTLVNPGEILECSISFPKFVEKLTRAPHFNVMFINMAMVGSRKLDLLGLLRDDEEGDGFDYAKRLREEGVHMITAFNYVTDTRTATCWLRYYCDCNAGISIPEIVRRLGDLELFGSRMRLCCLFPGIILGERPMPAALNGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQY4</accession>
    <name>E3QQY4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_08416</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697369">
        <property type="protein sequence ID" value="EFQ33272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097292.1">
        <property type="nucleotide sequence ID" value="XM_008099101.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQY4"/>
    <dbReference type="GeneID" id="24413781"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08416"/>
    <dbReference type="eggNOG" id="ENOG502SPMP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039960_0_0_1"/>
    <dbReference type="OrthoDB" id="21678at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01823">
        <property type="entry name" value="SEST_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037460">
        <property type="entry name" value="SEST-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37981">
        <property type="entry name" value="LIPASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37981:SF1">
        <property type="entry name" value="SGNH HYDROLASE-TYPE ESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ33272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="409" mass="45797" checksum="93677DAD222A40FF" modified="2011-01-11" version="1">MRLLAVLTPGSSQYVYTDGQRRPQRSVGFVAFGDSYSAGIGTGVDGVEDDCRLGSHAHPVLIFTDLAESQGASATTFQFLSCTGSTTGNVLSGGERSQIDSFNTSINADFAILSIGGNDLGFFRVMNACIFRFYSFYSGTCETALQYVADQIESPEFEHRLAMVIMEILDKIQWEKRPWFVVTVTGYARFFSVETDECDNCTLGVWWQGPKLKRDLRQRMNDMVVAVNDKLKRSIDAVNSRYSTPKVLFVDYDARFEGHRFCEPNVTEPAYDRTETWFFLVGGKDNNPNVTDPTPAPNSTSIKVDAGRARTLSPLSPLVDPDTCLDSAERSGDWGLLALCYMARAKRDDPSLRFAHEDVMIQDSMWYVPTYYGKTFHPRSLGHEAVKDEVYRTWSSLDIAAWLMPASSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQZ8</accession>
    <name>E3QQZ8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_08430</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697369">
        <property type="protein sequence ID" value="EFQ33286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097306.1">
        <property type="nucleotide sequence ID" value="XM_008099115.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQZ8"/>
    <dbReference type="STRING" id="645133.E3QQZ8"/>
    <dbReference type="GeneID" id="24413795"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08430"/>
    <dbReference type="eggNOG" id="ENOG502S178">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067862_1_0_1"/>
    <dbReference type="OrthoDB" id="2103474at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025187">
        <property type="entry name" value="DUF4112"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35519">
        <property type="entry name" value="MEMBRANE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35519:SF2">
        <property type="entry name" value="PH DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13430">
        <property type="entry name" value="DUF4112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ33286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="273" mass="30294" checksum="EC517F61000ADD42" modified="2011-01-11" version="1">MAGLIAKWISKKILAEKVENNFGREDPYFETVPATRLDGTPTGKVKKRRKALPPGISKQDGEVLTKVKRRAYRLDQSLFTCCGVKFGWGSVIGLIPAIGDVLDAFMAMMVFRTCSKVEGGLPNSVKSKMMFNIMIDFVIGLVPFVGDVADAAFRANTKNAIVLEEYLREKGKKNLRRSGAPIPAVDPSDAEEWDRLQGDRTPPEYVSREPSRNGRMSSSRQHSYNGRAPAAPANAAVRDERGRGWFGFSRSRADDIESARDPTDRPAPRKSMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3QR03</accession>
    <name>E3QR03_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cytoplasmic tRNA 2-thiolation protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">NCS2</name>
        <name evidence="3" type="synonym">CTU2</name>
        <name evidence="5" type="ORF">GLRG_08435</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CTU2/NCS2 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697369">
        <property type="protein sequence ID" value="EFQ33291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097311.1">
        <property type="nucleotide sequence ID" value="XM_008099120.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QR03"/>
    <dbReference type="STRING" id="645133.E3QR03"/>
    <dbReference type="GeneID" id="24413800"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08435"/>
    <dbReference type="eggNOG" id="KOG2594">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024534_3_0_1"/>
    <dbReference type="OrthoDB" id="25129at2759"/>
    <dbReference type="UniPathway" id="UPA00988"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016783">
        <property type="term" value="F:sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032447">
        <property type="term" value="P:protein urmylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002143">
        <property type="term" value="P:tRNA wobble position uridine thiolation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03054">
        <property type="entry name" value="CTU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019407">
        <property type="entry name" value="CTU2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20882">
        <property type="entry name" value="CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20882:SF14">
        <property type="entry name" value="CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10288">
        <property type="entry name" value="CTU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ33291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="390" mass="42906" checksum="0FB9A07E6F501CAC" modified="2011-01-11" version="1">MQDAHRPDSEEGPSMREAHRPRRPCYEQHIAQRVIKRLAQPYKDIKERIATTPAIKAKYLLGLSFGSSSASLVQLLDANLQGLKEKNLRVAYEVHVVHIDTDVSGAASTSSAEGSAASQLLEKYKERFPNISMQTVPLSDALALDTIDWSVLPALRTDLVPALQVKELIEALPSVTSRVDIMRLLVRHLLLSLALKSGCHALMLGCTTTALAELTLAETAKGRGFAVPWQVGNGPVPVTTFSRQGAEGKAAGAKEKTTIPVYYLLRDVFRREIVTYVGLVKPPMKDLIRDAGQGSSTIVSHKELSIEDVMARYFEEVEESYPSVVANVVRTSAKLTRENDGDACAVCGMDLDEQGEVRWKGEIGEHLDDNDRRKQTAGRMCYGCERSIYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QR30</accession>
    <name>E3QR30_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Domain found in IF2B/IF5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_08462</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eIF-2-beta/eIF-5 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697369">
        <property type="protein sequence ID" value="EFQ33318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097338.1">
        <property type="nucleotide sequence ID" value="XM_008099147.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QR30"/>
    <dbReference type="STRING" id="645133.E3QR30"/>
    <dbReference type="GeneID" id="24413827"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08462"/>
    <dbReference type="eggNOG" id="KOG2767">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026663_1_0_1"/>
    <dbReference type="OrthoDB" id="10250831at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043614">
        <property type="term" value="C:multi-eIF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071074">
        <property type="term" value="F:eukaryotic initiation factor eIF2 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005092">
        <property type="term" value="F:GDP-dissociation inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042256">
        <property type="term" value="P:cytosolic ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045947">
        <property type="term" value="P:negative regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd11561">
        <property type="entry name" value="W2_eIF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.180:FF:000031">
        <property type="entry name" value="Eukaryotic translation initiation factor 5"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Eukaryotic translation initiation factor 5"/>
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        <property type="entry name" value="Eukaryotic translation initiation factor 5"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045196">
        <property type="entry name" value="IF2/IF5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002735">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_dom"/>
    </dbReference>
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        <property type="entry name" value="Transl_init_fac_IF2/IF5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016190">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003307">
        <property type="entry name" value="W2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23001">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23001:SF7">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01873">
        <property type="entry name" value="eIF-5_eIF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02020">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00653">
        <property type="entry name" value="eIF2B_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00515">
        <property type="entry name" value="eIF5C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100966">
        <property type="entry name" value="Translation initiation factor 2 beta, aIF2beta, N-terminal domain"/>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF75689">
        <property type="entry name" value="Zinc-binding domain of translation initiation factor 2 beta"/>
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        <property type="entry name" value="W2"/>
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    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="255"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="146"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="173"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="188"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ33318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="422" mass="46951" checksum="98F68DA053EDA8FB" modified="2011-01-11" version="1">MASLINVRRDVKDAFYRYKMEKIVTKIEGKGNGIKTVVVNLSSVAQSLARPGAYVIKYFGFELGAQTNVDPADDRWIINGSHNAAKLQDHLDGFINKFVLCKKCKNPETDVNIKDGRILLDCKACGQRSEVDLRLKLSGYILKNQPKKGKKDKAERKAARRAKANGANKENGQGSGSGGEGSENGSNDADDQDVGSDDEFEKMKKEAPEVDNFETQEHEWAVDMSEGAVKARQAQLPVEFKQKLNIGDDDDEDGEATGNTVYDEFGTWIQDEASSKGGIDNVDSIDIFVKAKELGIEAKHRAVLVLVQTIFDENIVAQIPKRAGMMKQFITSDRHEKALLGGTERLIGQLSKDHPEIYSQIVKILQLYYNHDLLSEEVAVKWGSKASKKYTDLSISKKVRKAAEPFIKWLEEASEEESSDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRU0</accession>
    <name>E3QRU0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_08507</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EFQ33578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097598.1">
        <property type="nucleotide sequence ID" value="XM_008099407.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRU0"/>
    <dbReference type="GeneID" id="24413872"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08507"/>
    <dbReference type="HOGENOM" id="CLU_1927445_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ33578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="131" mass="14294" checksum="72F416744372DBD0" modified="2011-01-11" version="1">MCGGCSTINPQRRAPVDRVLSVAWTLKSLYAPFRCLWWPSRKGNGMWIRAPWYVIQESSAKKREPGGVAGDPDKAVDLGEVLYAVGGGGSGGGGHFFFSCYRTVYLVLVARTGEVFVIIVLAWDLCFTVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRU4</accession>
    <name>E3QRU4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GDSL-like Lipase/Acylhydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_08511</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697372">
        <property type="protein sequence ID" value="EFQ33582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097602.1">
        <property type="nucleotide sequence ID" value="XM_008099411.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRU4"/>
    <dbReference type="STRING" id="645133.E3QRU4"/>
    <dbReference type="GeneID" id="24413876"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08511"/>
    <dbReference type="eggNOG" id="ENOG502SIJX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044083_2_2_1"/>
    <dbReference type="OrthoDB" id="2119228at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004622">
        <property type="term" value="F:phosphatidylcholine lysophospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01833">
        <property type="entry name" value="XynB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051532">
        <property type="entry name" value="Ester_Hydrolysis_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383:SF5">
        <property type="entry name" value="SGNH HYDROLASE-TYPE ESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383">
        <property type="entry name" value="THIOESTERASE 1/PROTEASE 1/LYSOPHOSPHOLIPASE L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178763" evidence="1">
        <location>
            <begin position="20"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="2">
        <location>
            <begin position="44"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ33582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="296" mass="31908" checksum="9B5E401E0B7E705B" modified="2011-01-11" version="1">MRFSVACAALFAPLTVAAGDVLEYKSTPPGQVIKDGVKLRILPVGDSITYGFASSDGNGYRLELAQDLLANDVVFAGTIHSGNMTDGYSAGWSGKTIQYIADNVGPSLAQRPNIILLHAGTNDMNRNRDISVEGNDPVGAADRLGSLVDQMIAACPDATVLVAQIINTCLEDQRPATTEFQKLIPSVVDERKNAGYHVLAVDFASLGDAILRADCVHPTDGGYRIMGDYWYDFIAQIPNDWINNPFGNDPNRTKFQVASADKIVSSGASVATSQFKEKWLMSLAFQVVVTLMIMNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRW0</accession>
    <name>E3QRW0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08527</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697372">
        <property type="protein sequence ID" value="EFQ33598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097618.1">
        <property type="nucleotide sequence ID" value="XM_008099427.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRW0"/>
    <dbReference type="STRING" id="645133.E3QRW0"/>
    <dbReference type="GeneID" id="24413892"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08527"/>
    <dbReference type="eggNOG" id="ENOG502S2DX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007440_0_0_1"/>
    <dbReference type="OrthoDB" id="4115400at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="394"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="582"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="787"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1089"/>
            <end position="1154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1188"/>
            <end position="1210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="167"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="277"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="582"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="612"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="868"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="895"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="971"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="989"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1034"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1118"/>
            <end position="1132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1135"/>
            <end position="1148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ33598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1210" mass="131228" checksum="0FE1FD2D60E183AF" modified="2011-01-11" version="1">MDQRSRSSRPNRRKTLPTSSIQSDTSAGAESTSTIMTRSPPVAASRTPQTAPQNRRSVKVIPVNSPFSLRSSPSTTAPGPGKTALRKKSRAGFEGAADEDDEAYRKGPHTLRKRAKIDYSAADFEDELPEIAIPAPRAATRKRRADSEVADDEYSTPAAQKRRATSRDFSAASVAAATRRRTPARRSIVEPQSFHSQPSDEDIVKDTIEVVGDSSDLVSSDDASDHDEKDNDHSGRTSIPEKHEQPSSPIRRRALDVHQLMSPVDQQTVKRDDRHSSQAQDVSAVAAPSGMRSSPIMAHPRPIRFNHVTIINGPGSRPEAEQVPTHRTEFSQDFSFQPKREASSPVRPTESLPQRTALPEAVELATRQTVVFGSQESSALAVSGNHEATVAAATTNNDHVTVARPVEEVPQPAPKRDTHGEVVNGHVEAAKYDLPPHQQTESSQPPAAAMHGTEKHDIDAADSFSAQPEKSSQSKHDMNGNASEESDADTQHDVTVHPPKAASPRPTSIPKTTKKRYAWSHLTPYIDGEYVTHSIYPVAVEASAPASNADAAEAGGDAENADDAAYQADPNADYKQVDVDADEDGNADADADGEGDDVDRDAEHDEDLAPDSQGQPLSQGSAYNSAAPTPALTPRQGSPVLPAAITGTSTPAPLMPKQRFRKQYKFKKIRDPTEFAAYLKDTKELSDEELWYLLEKANECLVAYQEEYKKCTRIVDDQENAQRRAAQDTAFEKKTADLNAFAKVDSYIEKDFEVQGSRATIKEKDAGILDQRWQDRIMANAYGFEYDPHPNKIGNQDPGAQREGGGEGGRQLRSQPQASAKAAEGDGVIVSGKRARNPPKLFDGVLQDDHRAATPGSNKPGPRRRGRAAAADKAASQEQEPDEPEPQATSPARPGPKKRGPRGRRSAVVVSEPGTPVPEEDAVAPPPEPEQAQPLKRKRGRQPKSAAVVIEEPEPEEPEKPAPKRGRAAKRQSNGHVTSTAETTDESRPTSSSSNATISDDGSTYGLRQNKRHRNWKEETVADEEEPEPEPQPKKSRIIRINRKQSAPELAPRKTASEKILTELHDFSTSSTAPDSPRLTVSFKLIGKDHWTLKPAPSPRQTSTDVSEYNLATPRPAPVSAPASAKSSAPPSQAGEEKDYSTMTKSEKMSASMKKRWLNGSMQGAVNKRKATLAAKKQAAALAEAQAAQAAQQKAMSFQQIGPFPMGPSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSB5</accession>
    <name>E3QSB5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Beta-glucosidase cel3A</fullName>
            <ecNumber evidence="5">3.2.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Beta-D-glucoside glucohydrolase cel3A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Cellobiase cel3A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">Gentiobiase cel3A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">GLRG_08886</name>
    </gene>
    <organism evidence="21">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 22">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="5"/>
    <dbReference type="EMBL" id="GG697373">
        <property type="protein sequence ID" value="EFQ33742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097762.1">
        <property type="nucleotide sequence ID" value="XM_008099571.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSB5"/>
    <dbReference type="STRING" id="645133.E3QSB5"/>
    <dbReference type="GeneID" id="24414251"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08886"/>
    <dbReference type="eggNOG" id="ENOG502QR4D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004542_2_3_1"/>
    <dbReference type="OrthoDB" id="416222at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000757">
        <property type="entry name" value="Beta-glucosidase G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.300:FF:000002">
        <property type="entry name" value="Probable beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1700:FF:000003">
        <property type="entry name" value="Probable beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF28">
        <property type="entry name" value="BETA-GLUCOSIDASE L-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="8 20" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0964">Secreted</keyword>
    <keyword evidence="7 18" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="18">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179936" description="Beta-glucosidase cel3A" evidence="18">
        <location>
            <begin position="19"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type III-like" evidence="19">
        <location>
            <begin position="652"/>
            <end position="722"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00070030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00078013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00083231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00083611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EFQ33742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="734" mass="77248" checksum="012100A4B4EB3500" modified="2011-01-11" version="1">MHLSKIAFFAAATTLAAAQDSASPRRSPEWDAAYAKANAALSRVSLDEKIGIVSGIGWNNGPCVGNTSPASSISYPSLCLQDGPLGVRYARSVTAFVPGIQAAATWDLDLIRERGVLKATEAKGVGVHVMLGPACGALGKIPSAGRNWEGFGPDPYLMGIATKETIEGMQSAGVQATAKHYIANEQELNRETISSNVGDRALHELYLWPFAEAVKANVASAMCSYNKVNGTWACENDVVMNKLLKQELGFPGYIMTDWFATTGTVSGANSGLDMMMPGSNFNNEPWSVWWGPQLKTAVQNGQVSQATLDDKVRRILAAWYLVGQDRGSYPPVNLAADVQGNHKQNVRATARDGIVLLKNDNAILPLKKPGKIAVIGSSSVNNPAGINACVDRGCNTGTLGMGWGSGTVDYPYLVAPLDAMRQRAAQDGTQVSASSNDNAQQGAAAASGADAAFVFITANSGEGYITVDGNPGDRNNLDPWHNGNELVRAVAAANQNVVVVVHSTGPIILETILAQPGVKAVVWAGLGSQETGNALVDVLWGATNPNGKLPYTIGKTAADYGTSVSRGGQDDFAEGIFIDYRHFDQAGIEPRYEFGFGLSYTNYTYSGISVTSTATPGPAVGEVVPGGRADLFDVVATVTATVKNTGAVAGAEVAQLYITLPSGAAVSPPKQLRGFEKLRLAAGESATATFNLRRKDLSYWDVPSQNWILPKGSFRVRVGASSRNLALEGGLVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSL6</accession>
    <name>E3QSL6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08998</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697374">
        <property type="protein sequence ID" value="EFQ33854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097874.1">
        <property type="nucleotide sequence ID" value="XM_008099683.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSL6"/>
    <dbReference type="STRING" id="645133.E3QSL6"/>
    <dbReference type="GeneID" id="24414363"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08998"/>
    <dbReference type="eggNOG" id="ENOG502SMP1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110344_0_0_1"/>
    <dbReference type="OrthoDB" id="3365267at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ33854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="182" mass="19792" checksum="B268AFD793CDA838" modified="2011-01-11" version="1">MSRDSLAAFRKSPPSEDLAAIAEKHLEHDLLDSDRDLLKTAANKVRTHAVIGSAIGLGFGIFLASRLRRARAEMFAAFRAAEKPTHVKFADGRTEPIPDLTEELAPTRAGDIATYSLLGLGSLFLGGELGFLSGTSAASRTINRDPVSRARIETAFRKFRAEALRKEAERLDGGGRILDKIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSS0</accession>
    <name>E3QSS0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_09052</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697374">
        <property type="protein sequence ID" value="EFQ33908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097928.1">
        <property type="nucleotide sequence ID" value="XM_008099737.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSS0"/>
    <dbReference type="STRING" id="645133.E3QSS0"/>
    <dbReference type="GeneID" id="24414417"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09052"/>
    <dbReference type="eggNOG" id="ENOG502SKM2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_953189_0_0_1"/>
    <dbReference type="OrthoDB" id="4161332at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF83">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="9">
        <location>
            <begin position="176"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="125"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ33908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="292" mass="32882" checksum="502C2EC08F391332" modified="2011-01-11" version="1">MPQPERAVGHPKRRYTSKACEECRRRRAKCDGQRPSYVQLLRNRINLLEAVLQSRSIDVEASVAQLSTTGAAPQLPSVINLSASSSDAGLSPSAFDDLCATFEGALSLDKAVNYDQDGEMRYFGPSSGRLEFQSESTPENEEHRSSPTTTKPVETNRFILPLEAEVYPEDLQTELIDLFFEYQSPWCQVVDEKLFRESMKTQGRYYSPLLLNCILALGSRYSDRVDIRSDPTDQNTAGKPFMQKAEVLLHYDMKRPTITTLQSMLMAVMQQGVGCLERGPRGAPEWDQDQIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSX3</accession>
    <name>E3QSX3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_09105</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697375">
        <property type="protein sequence ID" value="EFQ33961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097981.1">
        <property type="nucleotide sequence ID" value="XM_008099790.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSX3"/>
    <dbReference type="STRING" id="645133.E3QSX3"/>
    <dbReference type="GeneID" id="24414470"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09105"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_44_5_1"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF274">
        <property type="entry name" value="CHAIN DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G00440)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ33961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="259" mass="27992" checksum="C333149075093545" modified="2011-01-11" version="1">MARIFITGSSDGLGAVAARTLLKKGHQVVIHARNAQRAEEAKLAVPDAETVLVGDLSKVDEVKRLAADANKLGTFDVIIHNAGFYRGPYQKTDLGLPTLYAVNVFAPYLLTALINRPKTLIYISSGLHKSGDSSFTDPTWRERGEQGWNDDQAYCDSKLHITTFANAIARLWPDVKSNSVDPGWVPTKMGGQSATGKAEDGVASYVLLAEGTGAGDVTGKYFKPPGQEDDSVPFTSDEKRQDELLKLLEQETGVMLPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSY6</accession>
    <name>E3QSY6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_09118</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697375">
        <property type="protein sequence ID" value="EFQ33974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097994.1">
        <property type="nucleotide sequence ID" value="XM_008099803.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSY6"/>
    <dbReference type="STRING" id="645133.E3QSY6"/>
    <dbReference type="GeneID" id="24414483"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09118"/>
    <dbReference type="eggNOG" id="ENOG502RYMZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005679_13_5_1"/>
    <dbReference type="OrthoDB" id="5819582at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050879">
        <property type="entry name" value="Acyltransferase_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028">
        <property type="entry name" value="ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028:SF134">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08520)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="246"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="367"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="405"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="441"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="Acyltransferase 3" evidence="2">
        <location>
            <begin position="45"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ33974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="489" mass="55294" checksum="F76A4C7959CD2146" modified="2011-01-11" version="1" fragment="single">NEGIPVAQHLPTWLRYGKRALWILMPTFLHPSSTKVTPKPLHPSAWLDGLRGISALFVVCHHWSLVVMPANMRRGFMTDDYPMFLQLPIIRLTVTGFSAVSVFFVISGYALSYKPAKLAAQTKNVDFLTAVASSVFRRYVRLFLPIMATSFVIACLAYFRLFEVAPVPNQAVVWGRPPVLDTFFDQMKNWCSQFGSLADPISKDIGRGGRFTYDPVLWTIPFEYDGSMLVFLTQIAFYRLRPRIRILFNILIVVYSIHSGYWQYFLFLSGLCIATLHFHAQVKHGAHEPASLTLPLTSTTWTFETFGSSFSPLVAPGRKDIRNKAIQIASFLGALWLLSYPDSTAAIAPGYRTIFTLTPTSYGAEDYRFWVSIAAVWLVFTVDKSPVIQPLFTNRYAQYLGRISYSIYLVHFSMIWLYGIHVIRFFAVVTGSAFEANSASVSWAVSAILATIFFLPVTLSLADFVQRYVDVQSVEFSAWLETKVVSRTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTP6</accession>
    <name>E3QTP6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">FPD1 benzoylformate decarboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_09352</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697378">
        <property type="protein sequence ID" value="EFQ34208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098228.1">
        <property type="nucleotide sequence ID" value="XM_008100037.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTP6"/>
    <dbReference type="GeneID" id="24414717"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09352"/>
    <dbReference type="eggNOG" id="ENOG502S43V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054062_0_0_1"/>
    <dbReference type="OrthoDB" id="19714at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034715">
        <property type="term" value="C:pICln-Sm protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039924">
        <property type="entry name" value="ICln/Lot5/Saf5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21399">
        <property type="entry name" value="CHLORIDE CONDUCTANCE REGULATORY PROTEIN ICLN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21399:SF0">
        <property type="entry name" value="METHYLOSOME SUBUNIT PICLN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03517">
        <property type="entry name" value="Voldacs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="269"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="282"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="305"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ34208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="319" mass="33765" checksum="DD8F3804DD4B352A" modified="2011-01-11" version="1">MSSLTAQPKQSPLQDLFDIITMLPTTIRSPPSLGDFTPIEDHQSQTPETFFGGKPVLHFHLEGAKAWIPASQKGNLAVFPADVATTASAPEGATLNEVSEELVEQKVSVFVNSENFTIFSEAQGAGVEVPYPSISIHAVKQVGTMAEGAPLQAIWMQLQLADGGDGDEDFDTIDLTLVPTVTSGAQVDVQKFYDAISACSDLHPDPVDDDDEEEDGRIVFEGELEPVEGYTGVMYGAHDGGLPPAFPGSGGWITAENVHEHFDADGNWIGQNGDGEAEEGGGGELGEGAGRVRGHDEVNGGGVNGHDDPDNKRPRVDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTZ0</accession>
    <name>E3QTZ0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">1-alkyl-2-acetylglycerophosphocholine esterase</fullName>
            <ecNumber evidence="1">3.1.1.47</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_09472</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.1.47" evidence="1"/>
    <dbReference type="EMBL" id="GG697379">
        <property type="protein sequence ID" value="EFQ34328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098348.1">
        <property type="nucleotide sequence ID" value="XM_008100157.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTZ0"/>
    <dbReference type="STRING" id="645133.E3QTZ0"/>
    <dbReference type="ESTHER" id="colgm-e3qtz0">
        <property type="family name" value="PAF-Acetylhydrolase"/>
    </dbReference>
    <dbReference type="GeneID" id="24414837"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09472"/>
    <dbReference type="eggNOG" id="KOG3847">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026278_0_0_1"/>
    <dbReference type="OrthoDB" id="2363873at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003847">
        <property type="term" value="F:1-alkyl-2-acetylglycerophosphocholine esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10272:SF14">
        <property type="entry name" value="PAF ACETYLHYDROLASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10272">
        <property type="entry name" value="PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03403">
        <property type="entry name" value="PAF-AH_p_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012542335" description="1-alkyl-2-acetylglycerophosphocholine esterase" evidence="5">
        <location>
            <begin position="16"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ34328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="383" mass="41288" checksum="8D83CE21EFD62735" modified="2011-01-11" version="1">MIFSIFLGLASVAAAVVIPGPPGPHPVALRVRAFEDAARWDPHAPKDQPERRRVMVSVNIPIKKEIRCSAETLPYMPPITTSVYGKMAAEMYGLPDTLLSGLELEFCHVKAPCASKADKYPLVVFSPARALTRLAYGVLARSLASYGYIVVTVDHTYEATVVEFPDGSVRYAENATNSDEDYVESLLDSRQKDVSFVIDQLLDTSAVDSLMTGTQASIDPDKIFVAGHSLGGATAATSLYADDRILGGLNFDGLIIGPVATEGTHKPLVLVGTPTSTDYVPGWNETWPNLRGPSLMLAVAGTTHLSFFDIAKLLTVLALPAEFDELIEQALGPIQSGTLEKIKNELLLRTLDFVLENKKDALCGIESIGPEVKQLQGKNLSCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUE1</accession>
    <name>E3QUE1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09623</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697380">
        <property type="protein sequence ID" value="EFQ34479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098499.1">
        <property type="nucleotide sequence ID" value="XM_008100308.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUE1"/>
    <dbReference type="GeneID" id="24414988"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09623"/>
    <dbReference type="HOGENOM" id="CLU_2960631_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="59" mass="6407" checksum="D69C5E5AD3A36CF3" modified="2011-01-11" version="1">MSTGATPEGSRSDIAGKLTQHQYLSGSATIGNRIRTSGNAQQGNEEEEEEEEARQQVRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QV23</accession>
    <name>E3QV23_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mitochondrial fission process protein 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Mitochondrial 18 kDa protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_09857</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MTFP1 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EFQ34713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008100542.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QV23"/>
    <dbReference type="GeneID" id="24415222"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09857"/>
    <dbReference type="eggNOG" id="ENOG502RZGV">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_053720_0_0_1"/>
    <dbReference type="OrthoDB" id="424969at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
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    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="P:mitochondrial fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="Mitochondrial_18_kDa_protein"/>
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    <dbReference type="PANTHER" id="PTHR11001">
        <property type="entry name" value="MITOCHONDRIAL FISSION PROCESS PROTEIN 1"/>
        <property type="match status" value="1"/>
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    <dbReference type="PANTHER" id="PTHR11001:SF2">
        <property type="entry name" value="MITOCHONDRIAL FISSION PROCESS PROTEIN 1"/>
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        <property type="entry name" value="MTP18"/>
        <property type="match status" value="1"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00009224"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ34713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="288" mass="32042" checksum="A066B8B0A9E94E54" modified="2011-01-11" version="1">MWGRSQNKTPEQPKESPKEDGAKTFDPEKLPPREKLPKALQKIVDKSDSDDNFFDELVDGYAPESTESNLRYAAYATRIRTILMSAHRYVAYTSDIGESFRPVAHPALVRSAYGISWLYILGDVSYEGYKAYWANQRILNPHLQLTARQAKLTGLPGAVSDATTPSEVVPAGKVTPLNDYRTVMVQRAIFQSIASMGLPAFTIHSVVKYSGRALKNAKNPKIRTWAPIGLGLAVVPFLPSLFDEPVENAVEWVFHRGFELYGGKEFVGDAPATGREDLLAKKPKEKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QV56</accession>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
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    </protein>
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        <name evidence="3" type="ORF">GLRG_09890</name>
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    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
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        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
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                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EFQ34746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008100575.1"/>
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    <dbReference type="GeneID" id="24415255"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09890"/>
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    <dbReference type="OrthoDB" id="1896086at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180998" evidence="2">
        <location>
            <begin position="37"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ34746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="487" mass="54612" checksum="5CE66A8713E11914" modified="2011-01-11" version="1">METISFSATSSKGKGVMVGFCLLVEVFLRGVTGARSQPDSKKVFPFEHNWDPANPPLWSIRSEDHELFTVGRSSPVQIRDTDAKTAGFTSLKHTWDPHNPPLWTVRPEDRQKVPGQHYSQMAEASKSSEETDPCANKDKPATLYKTYENNECPPKHKFLPLEKGMGFADTCEGWNTEDFRKHDCITFCQTSTRFEWAQEVPFPHSECHFPISCGLSEGDSVKSGWNMGGNVKVQFIKALKIGVTGGYSSDWSESEGRKFDVNLTEGQCGYFTFVPVKRIVCGGITEPDYPPRWYDFGLCKAGPKNTHLCVDKLWTIKSQRIKDPNHEIPDGTIIFVYTDCFSRRPLPMNKQDPVYHAPGVALHHDVLDGIRQSWVWNTCYMWNMGAEGKLSLYIHGSGFKDSMVGPEGKKLIERVNHCARSVDGVISGAEFNWYYSVYPGEDPKITGAMWVFMADVPSNIRPGCLGDAMIELGGITKDKCIGDKFEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVH2</accession>
    <name>E3QVH2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glucan 1, 4-alpha-glucosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10004</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EFQ34860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098880.1">
        <property type="nucleotide sequence ID" value="XM_008100689.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVH2"/>
    <dbReference type="STRING" id="645133.E3QVH2"/>
    <dbReference type="GeneID" id="24415369"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10004"/>
    <dbReference type="eggNOG" id="ENOG502SBSC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022438_0_0_1"/>
    <dbReference type="OrthoDB" id="3941134at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="479"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="536"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="575"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="221"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <begin position="286"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
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            <begin position="543"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="595"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="608"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="641"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="695"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="725"/>
            <end position="736"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="782" mass="83933" checksum="C527DE41B4E8F0AE" modified="2011-01-11" version="1">MDDPWGSPWATTDTTTAPSTSPSKNRLEPPPPAFLSTPNSLTIPSSQSAWLDDDPYGGWASHDPGQATNTSPWIWGNEAAPIEGLTPSYEPRRKSSIPRWPRSQSPSPALGSRITPNIVSPGQPSPDPWAHHVSTYTRDDPEPVAQLPQIPDVLPPVLESAQVGLGLTDSTNPFEQDFVTHEPIATQFADPMPNSTHEHLKFSDTPLSDFFPPTTKHGDEAAPSSASALSEDGGDNDEATSIEDNAAPKTSQRKASGKVLELVEMYDGIAKRRATTPERIIPRRSSSREPKTAASDISDHGSEADKQPEADKEVQPRGSIYVDSRSLPDDRDESIGHIDEVPKSIRPDHDPFDIDLGKLNLLLPGTSEEVSVPSQDVSDRIVHDSFTSIPERKMWYRLSRNESLRKHNAGDDDNYVRINWTNSTLRQETLKTVRRWIEEDSFGGRAFRSGSAGNTGSKNFGWDATTAASPVDLDRVFGRKQKRQPAVPRPTSTGGLPPLSTFPMVPASTGNTPISAQANGNWEGLAAFGWSSGAGDTKQVTEANASRPSAPSIPIPLAFTGFDNKPKSHASLPAFIKPIAPTPPTLKATSPAAEEAGEAEDEWGDMVSPTTAEATDSASLPKTSWDSFSTNPLPEVASMPPSDSFTTSNPDSDVLRTGFYDDGNFRDKSGRGIVGSGMSPTPAPTQAQAGVPDVPQSQDGFSDISRSASTVKRLASKNLSDPQTASSSGEAGFSAEGTVKTGLTTGLHTGSTTQPLNAHSTEGFDIVHRFVRNLPDLSYMLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3QW44</accession>
    <name>E3QW44_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin 3 binding protein But2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10226</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697387">
        <property type="protein sequence ID" value="EFQ35082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099102.1">
        <property type="nucleotide sequence ID" value="XM_008100911.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QW44"/>
    <dbReference type="GeneID" id="24415591"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10226"/>
    <dbReference type="eggNOG" id="ENOG502SEQW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102611_0_0_1"/>
    <dbReference type="OrthoDB" id="5308323at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179987" description="Ubiquitin 3 binding protein But2 C-terminal domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="175" mass="17620" checksum="20426C98AFCC76A0" modified="2011-01-11" version="1">MQLTNILIAALAAAASAAARTTPSARRFAAPNPNCRIVPASDINFGVADLASGTVVTKVLTFPVGSASAGSCQLIGAFAEGFPIDQGGGDLARLDVRALGGPAPGSLVGSFGPLKVAGDAVVEDTVQFINSFQCAESLSFEFAVANDAGVDEDINVAFTASHLGGFFVLVGDQCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>E3QW60</accession>
    <name>E3QW60_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Male sterility protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_10238</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697388">
        <property type="protein sequence ID" value="EFQ35094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099114.1">
        <property type="nucleotide sequence ID" value="XM_008100923.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QW60"/>
    <dbReference type="STRING" id="645133.E3QW60"/>
    <dbReference type="GeneID" id="24415603"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10238"/>
    <dbReference type="eggNOG" id="KOG1176">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1178">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002220_2_1_1"/>
    <dbReference type="OrthoDB" id="429813at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051414">
        <property type="entry name" value="Adenylate-forming_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="FAR_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43439:SF2">
        <property type="entry name" value="ENZYME, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43439">
        <property type="entry name" value="PHENYLACETATE-COENZYME A LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23562">
        <property type="entry name" value="AMP-binding_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="607"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ35094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1094" mass="120448" checksum="9C90E3D89E696B37" modified="2011-01-11" version="1">MAPIATSDLKSDLPSTMVDPSVFPSPNADKELTRLWNLHGEPHSTNFSNPSLSSIAALVRHNAATQPLQAAFISPVDNSFEVFNWSTLQNLCCEASGYYSEKLRNEIEHANQTGQQPTVALLGTGTSIDYLVTQIALNSLHIRVLLLSNKNSPATRDHLLQVCNAVAIVVDKANGASLGEGEACRLSIVDLASLADLRESSQKAPKDKIAFETTDEWNLQSMIIHSSGSTGMPKPIIHTNRSLCQIARMYRLLPEYFIENWYLCFPLFHIAGLSIVLSGIPTGLPTSLPPANWPPAPSSILSAWKALEEIGYPADCLHCAPSVIEDLYEYISLTTKDFTPLTRLKVLQPGGAPLSPAMLKKLQALGVNVKTTYGTTEIGPPLRTIPHTKDNPDVYRFRNLYPESPLVQMEPLGDGLFECVVYKGFPLAAELWLDKSAPNPYRTGDLFLQDPPGTGYFVLQGRRDDILVHSNGEKTHATALAMSLEENKTSIISKTAVFGTGKPCPSLVVEIRWDRWDKVRETSDMHLDEAVWEVVQECNEKVAAYSRIPREIILILGRDETLPVTPKGNVRRNIAWESYGDRVEDLYNRFLGDTSTTDGLDNVIPSDADISPAETIQRAVAGVLGLSQEDIAEDQDWYGLGLDSLRAVELRSKLVKVYGSFPLMFIFEYPTVKGLLGFLQNYKREGSGGEASVQDQHHAWAESTIQHMNREIDQWATLAPQSIGNSPDNGEVVYLTGASGALGNALLEVLVQLPAVKKVYCAVRGADSQARVRDSMKSRGYSEHIYQSEKIFAVDYDMKDTSLGLDGQTFELLASEVTLVMHNAWKLDFNQPIQQFENDCLRGTMNLMSFCLRGAKKKFVFMSSVAAAMGNQSGTIVPELPLGPDPANALSTGYAQSKFIVEQVTQHYASVLKMPVHILRVGQLCGHSRLGVWNHTEMWPILMMTGLDVLSAMPVLQTKVDWLPVDICAEAIQKAVFSSADESPYAVTNLVNPAPISWDELLSLLREASGLEFARVEMSEWVSLLETQTSPAGPQDHKTPALKLLSFFQEMAKGSGNGEGVVFEASKVGGGRRIDVHMVGKWLEKWQQAGLRGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWB9</accession>
    <name>E3QWB9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_10301</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697389">
        <property type="protein sequence ID" value="EFQ35157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099177.1">
        <property type="nucleotide sequence ID" value="XM_008100986.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWB9"/>
    <dbReference type="STRING" id="645133.E3QWB9"/>
    <dbReference type="GeneID" id="24415666"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10301"/>
    <dbReference type="eggNOG" id="KOG0159">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_11_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11058">
        <property type="entry name" value="CYP60B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF210">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ASQL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="464"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ35157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="519" mass="58074" checksum="A5F24A24006E63BA" modified="2011-01-11" version="1">MAVLGLLSEPLASLPMSVWTAALIVLAVVLKATYNLFFHPLRSYPGPLLWRASRLPYVIRFSRGQIPYDLKRLHAKYGPVVRIAPDELTYNCAQAWVDIYGRNKQANGETTLFNKDPILYSAVFAEHKALIDSDGDEHRPQKRTLAYAFSHQALVERGHIITGCIDRMIEGLNAYIGTPSVSVDGSSAVVDIGAWTENALFDLGGQLTVGRDLNAIMSQGTVHPSLALFKRLFDWVQCYYLQFRRSPKFLVNAIESMPGFTGYDCVLPVKDVHDMTLKRMAEEKHVGGDNSGDFASYLMSRAKSEGLEDDKVWINCVHLILGTPEAMPSSIISTIYHLLTTPYAYAAAVKEIRGAFKSSDEITAQDVQNLPYLLACFRETLRRRPTIPGTLTRQVPPAGAHICGKFVQGGTVVGVNQFATSRSASNFYDADSYRPERWLDPRPAEFENDDRNAFNPFGYGPRKCIARNLAHLTTQTFLAKLLWEFDMELDESCRNWDDQGLYVLAKRGPLLVKLRKAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWF9</accession>
    <name>E3QWF9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10341</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697389">
        <property type="protein sequence ID" value="EFQ35197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099217.1">
        <property type="nucleotide sequence ID" value="XM_008101026.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWF9"/>
    <dbReference type="GeneID" id="24415706"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10341"/>
    <dbReference type="HOGENOM" id="CLU_2596481_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="80" mass="8688" checksum="5B374C27E3E79B3F" modified="2011-01-11" version="1" fragment="single">LLPENLHSPSHHIPSSHPPLVKKGSAIPPPSCLANHCGLMCVHTYCNSRYPSVLRTHTDMSDDSIAQLRPRGTQQPASPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWL2</accession>
    <name>E3QWL2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">pH-response regulator protein palC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_10394</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the palC family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697390">
        <property type="protein sequence ID" value="EFQ35250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099270.1">
        <property type="nucleotide sequence ID" value="XM_008101079.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWL2"/>
    <dbReference type="STRING" id="645133.E3QWL2"/>
    <dbReference type="GeneID" id="24415759"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10394"/>
    <dbReference type="eggNOG" id="ENOG502QWTM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023703_0_0_1"/>
    <dbReference type="OrthoDB" id="10266451at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071467">
        <property type="term" value="P:cellular response to pH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09245">
        <property type="entry name" value="BRO1_UmRIM23-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.280:FF:000005">
        <property type="entry name" value="pH-response regulator protein palC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.280">
        <property type="entry name" value="alix/aip1 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004328">
        <property type="entry name" value="BRO1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038499">
        <property type="entry name" value="BRO1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037505">
        <property type="entry name" value="pH-resp_palC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40463">
        <property type="entry name" value="PH-RESPONSE REGULATOR PROTEIN PALC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40463:SF1">
        <property type="entry name" value="PH-RESPONSE REGULATOR PROTEIN PALC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03097">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01041">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51180">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRO1" evidence="4">
        <location>
            <begin position="1"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="433"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ35250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="477" mass="52308" checksum="744FAE06E11036F9" modified="2011-01-11" version="1">MPFPFILPTTSAFSFSSSFSSDTHPSLPLSSSTYRGVVRDALKKHKRLPPASQSSHVSTVVGALNGYIPYILAIDAGLNPATQSGDYINLNTKAPPSIEWRPTLSDNAVPGREQSRVKIQHVEHEIFFTLSTLANSYTLIARAALHPLYVATQAALDNQQRTAAIQTATKYLLDAASIYDYIASRAERAQVEPPCSDVSPSTLRAMSSLALAEATMLAVLKDDPYPAIIAQDRNKNDREWMYKAPEIPKVRAHLFARLCLAAAEHASQASSLCQAAGRGSSKVNEGILRYLEDLRRTCRAKACRFFGIDAEIGGQVGTAIAWLQAGLQELGVESKYSNKSSGFGRFKKEWSEKREERKVEKGTTWGADGGKGEETRVIEFLEGKWHKLNDTMNVQTIPPIGPLLAQMPSGRAMHTLKPYQPPILDRSILEAMRAPPERSDDYGDSLSSEDEAKGHSGPPGGYPESRPEYRSGSTSYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWX7</accession>
    <name>E3QWX7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">L-fucose mutarotase</fullName>
            <ecNumber evidence="3">5.1.3.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_10509</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>alpha-L-fucose = beta-L-fucose</text>
            <dbReference type="Rhea" id="RHEA:25580"/>
            <dbReference type="ChEBI" id="CHEBI:42548"/>
            <dbReference type="ChEBI" id="CHEBI:42589"/>
            <dbReference type="EC" id="5.1.3.29"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="5.1.3.29" evidence="3"/>
    <dbReference type="EMBL" id="GG697392">
        <property type="protein sequence ID" value="EFQ35365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099385.1">
        <property type="nucleotide sequence ID" value="XM_008101194.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWX7"/>
    <dbReference type="GeneID" id="24415874"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10509"/>
    <dbReference type="eggNOG" id="ENOG502RZR7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120075_1_0_1"/>
    <dbReference type="OrthoDB" id="10011710at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042806">
        <property type="term" value="F:fucose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036373">
        <property type="term" value="F:L-fucose mutarotase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006004">
        <property type="term" value="P:fucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1650.10">
        <property type="entry name" value="RbsD-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023750">
        <property type="entry name" value="RbsD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050443">
        <property type="entry name" value="RbsD/FucU_mutarotase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007721">
        <property type="entry name" value="RbsD_FucU"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF011949">
        <property type="entry name" value="PRK15420.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31690">
        <property type="entry name" value="FUCOSE MUTAROTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31690:SF4">
        <property type="entry name" value="FUCOSE MUTAROTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05025">
        <property type="entry name" value="RbsD_FucU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102546">
        <property type="entry name" value="RbsD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00036324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ35365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="145" mass="15833" checksum="EFF1CA4E8095DDAD" modified="2011-01-11" version="1">MPLKGISPVISPDLLKVLAEMGHGDEIVLADAHFPSHSICPPHIPVLRADGITVSRLLAGISPLLELDNYGVVPVLMMEVVKGDTFDASVEGDFRSSLKYDGEIEKLERFAFYERAKKAFAIVATGETRKYGNIILKKGVTPIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXK5</accession>
    <name>E3QXK5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10737</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697396">
        <property type="protein sequence ID" value="EFQ35593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099613.1">
        <property type="nucleotide sequence ID" value="XM_008101422.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXK5"/>
    <dbReference type="GeneID" id="24416102"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10737"/>
    <dbReference type="HOGENOM" id="CLU_2399540_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="93" mass="10148" checksum="51AC0D45AC19D48F" modified="2011-01-11" version="1">MDDECKYALGTLSFEKRASTSSKFGRSPENLPPGGHGDQQSLGAEPYQSGGVPVSAVPKYRQRDGKSELAEFEDAGLTCTSDYPVREEERCDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QY69</accession>
    <name>E3QY69_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Endoribonuclease L-PSP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_11002</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697400">
        <property type="protein sequence ID" value="EFQ35807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099827.1">
        <property type="nucleotide sequence ID" value="XM_008101636.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QY69"/>
    <dbReference type="STRING" id="645133.E3QY69"/>
    <dbReference type="GeneID" id="24416367"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11002"/>
    <dbReference type="eggNOG" id="KOG1399">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1575">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_304414_0_0_1"/>
    <dbReference type="OrthoDB" id="686384at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19101">
        <property type="entry name" value="AKR_unchar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06154">
        <property type="entry name" value="YjgF_YER057c_UK114_like_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="entry name" value="RutC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43147:SF2">
        <property type="entry name" value="NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43147">
        <property type="entry name" value="PROTEIN TAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="YjgF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="5">
        <location>
            <begin position="487"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ35807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="976" mass="104548" checksum="9249E8E32639A32B" modified="2011-01-11" version="1">MACQTNSEAEDRPFGPLPRTSSPSSIIGADQRGRPEAQGLPRVEDGKVLDAVVVGGSCNGIANAIRLDAAGAEIAVFDMEARAGGNWSTKRYEGVMLHHPAFMVQLPLFPVPEGEGYPNYLTGQDLTRYYSSAVERLRLPFFGGVEVVGNAWDEGAGLWTVTVKDVATGAAARLRARNVVVSTGLTVTDQNPRVTALAGRETFAGPVQHTAAYRNPEAYRGRRVVVVGSGNSAHDVAATLARDGGVASVTLLQRSPTVLLDFDAVGPAFARRYGGQTPVDTADFLEGALPLGVVRDVTRAGFRALIAASEERNRALEGVGYMLDREPCLMTRVFEEKGRAFYADQPGTFKLVLDGRIKVARGEARGFVERGLVVVDRQTGRERVVEADGVVLATGFEVMDMPRRYKNKGFVDADTADRLVNVNENGVDAEGEQPGLTTFSGLLFRKRKKNAHSCIVIGFAQKKTMASTLPPRVERTTIAGSIEIPRMLHGLWQLAGGHDRDVDVAAAAEAMGPLIDVGLDGFDMADHYGPAELVVGRHNLTSSRRPITAFTKWCPPESGDRSFATAEAAVDLALRRMAQERVALMQYHIWDYSDDTYLCNLAHLGALQRQGKISHVGVTNVDAAHLELLLDSGYAIATNQVSCSVVDRRLVRGRMAGVCARRGVGVLAYGTLLGGFLSEKWIGAPEPTSAEGLNWSLRKYLRFIRAAGGWAAFQGVLKAVAAVAEKHGVPVAAVATRWVLDIPVVKAVIVGARLSGESGKYTAGNLAAFGLSLDDEDRTAIAKAQEALADIPGDCGDEYRRAPFLTAAGDLSDHVKGGDGERRRREVEEAVTGGGRVEYRTGSKWEPVAGYSRAVRVGSVIRVSGTTANPPTELGSQLAAVGGESARSQTVAVLDTIERAVRRLGGSMSDVVRTRVMIRREEDVEEVSEAHGWVFQCHGVRPANTLTTAGLIGDEMLVEIEAEAVVGSSESVLVVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZ39</accession>
    <name>E3QZ39_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein DOM34 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_11271</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the Dom34-Hbs1 complex, a complex that recognizes stalled ribosomes and triggers the No-Go Decay (NGD) pathway (PubMed:20890290). In the Dom34-Hbs1 complex, dom34 recognizes ribosomes stalled at the 3' end of an mRNA and engages stalled ribosomes by destabilizing mRNA in the mRNA channel. Following ribosome-binding, the Dom34-Hbs1 complex promotes the disassembly of stalled ribosomes, followed by degradation of damaged mRNAs as part of the NGD pathway.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the eukaryotic release factor 1 family. Pelota subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697409">
        <property type="protein sequence ID" value="EFQ36127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100147.1">
        <property type="nucleotide sequence ID" value="XM_008101956.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZ39"/>
    <dbReference type="STRING" id="645133.E3QZ39"/>
    <dbReference type="GeneID" id="24416636"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11271"/>
    <dbReference type="eggNOG" id="KOG2869">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023334_3_1_1"/>
    <dbReference type="OrthoDB" id="10249111at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990533">
        <property type="term" value="C:Dom34-Hbs1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070651">
        <property type="term" value="P:nonfunctional rRNA decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070966">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, no-go decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070481">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, non-stop decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032790">
        <property type="term" value="P:ribosome disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071025">
        <property type="term" value="P:RNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.60:FF:000004">
        <property type="entry name" value="Protein DOM34 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.870:FF:000001">
        <property type="entry name" value="Protein pelota homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.30:FF:000008">
        <property type="entry name" value="Protein pelota homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.60">
        <property type="entry name" value="eRF1 domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.870">
        <property type="entry name" value="Pelota, domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042226">
        <property type="entry name" value="eFR1_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005141">
        <property type="entry name" value="eRF1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005142">
        <property type="entry name" value="eRF1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005140">
        <property type="entry name" value="eRF1_Pelota-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038069">
        <property type="entry name" value="Pelota/DOM34_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058547">
        <property type="entry name" value="Pelota_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004405">
        <property type="entry name" value="TF_pelota"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00111">
        <property type="entry name" value="pelota"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10853">
        <property type="entry name" value="PELOTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10853:SF0">
        <property type="entry name" value="PROTEIN PELOTA HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03464">
        <property type="entry name" value="eRF1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03465">
        <property type="entry name" value="eRF1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26356">
        <property type="entry name" value="Pelota_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01194">
        <property type="entry name" value="eRF1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159065">
        <property type="entry name" value="Dom34/Pelota N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53137">
        <property type="entry name" value="Translational machinery components"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0132">Cell division</keyword>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0469">Meiosis</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0498">Mitosis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="eRF1/Pelota-like N-terminal" evidence="12">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="378"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="378"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="388"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ36127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="399" mass="43622" checksum="44AD416999222930" modified="2011-01-11" version="1">MKLVPTKASTDIGEDAVTLLPEDSEDMWHAYNLISPGDLVMAHAVRKVVQETKTGSTISERVHTILAIQVKSTFFDPIVGQLQVSGTVKSENAYVSMGQYHTLDLEVSRPFTISKPEGWDTVAKETLSESLSDDKDGAMAAVVMQEGIANICLISQFRTVIKQRVESIIPKKRSTASETSQGMRRFYDKTLTALLRTVNFDKPRPLLLASPGFVATDFKKYIADEGRDKADKKLSGIAKEAIVIHTNSGHVHSLNEVLKSPEMGNKLKDFKFTKETKLMDQFFERLRLEDGRAWYGASAVAKAVNEGAIGPGGGVLIMNNSLFRSSDIPTRKKYVGLVDKVKADGGEVRILSSDHESGQRLDMLGSVAAILSYPIHDLDDDEEDDGEATAGDAGGETII</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZH3</accession>
    <name>E3QZH3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Capsular associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_11406</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697416">
        <property type="protein sequence ID" value="EFQ36261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100281.1">
        <property type="nucleotide sequence ID" value="XM_008102090.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZH3"/>
    <dbReference type="GeneID" id="24416770"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11406"/>
    <dbReference type="eggNOG" id="KOG2458">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005027_4_2_1"/>
    <dbReference type="OrthoDB" id="541052at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006598">
        <property type="entry name" value="CAP10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051091">
        <property type="entry name" value="O-Glucosyltr/Glycosyltrsf_90"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203:SF22">
        <property type="entry name" value="CAPSULE ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203">
        <property type="entry name" value="KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05686">
        <property type="entry name" value="Glyco_transf_90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00672">
        <property type="entry name" value="CAP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl transferase CAP10" evidence="2">
        <location>
            <begin position="377"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ36261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="686" mass="76867" checksum="1FC1A91276E324F0" modified="2011-01-11" version="1">MVKLLTPAFPPRRPSSFLRCAAVVIFVIALFYHFDPRYPREPPTRLQSEKPGQTTQKENPVPPPPTQADGSEKPIPQPESTPILPSVQTHNAAAAAAAAAAAATSAAVGKPVPGGSKPADGSSKKPHPIDTLIKEAGETFDGLLNKESKTLKDAAKAYRERRGRHPPPGFDAWFQFAQDRRAVIVEDFFDQIYHDLRPFWGVEPSRIRKEAAEWEMVIQVRKGRASRESDWFWTVHWTDMIKTIEHLLPDMDIPLNAMDEPRMVVAFEDMEQYLKNAALAQAQGMPDPTQVVSKFQTLPKNKKELDRNVKVQKKHWDKVTKQFWLIARRGCPPDSPARLAKAQTTFDHPPNISTKYAAAHMRDGFVSNFTLSTQLCHQPDLQGLNGIFIEPLSTSATPVLFPLFGGSKLAVNNEILLPAAMYWTTEERFSGGGDHGESWEEKRDEASFQRHRFVAMNNGTKVTAAEKGTAAAAAAAAPPTVNFALPDNRLYDIAARAAGALGDWVRSWADVGFTDLMCEPHNEDGGGECNYTSPHFSLVESVSMADMYYSKYLPDIDGNSFSGRYLAFLSSTSLPIKATLWREWHDSRLVAWKHFVPMDSRFGDYYGIMDYFLGYGAERPGHDAEAERIASDGKAWAERALRREDMQIYTLRLLLEYARVTDERREKMGWVDDLLAEQKKPAEKTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3R054</accession>
    <name>E3R054_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Tat pathway signal sequence</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_11637</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Mycotoxin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ustYa family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697427">
        <property type="protein sequence ID" value="EFQ36492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100512.1">
        <property type="nucleotide sequence ID" value="XM_008102321.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R054"/>
    <dbReference type="STRING" id="645133.E3R054"/>
    <dbReference type="GeneID" id="24417001"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11637"/>
    <dbReference type="eggNOG" id="ENOG502SNCH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042941_4_0_1"/>
    <dbReference type="OrthoDB" id="3687641at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043386">
        <property type="term" value="P:mycotoxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365:SF11">
        <property type="entry name" value="TAT PATHWAY SIGNAL SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365">
        <property type="entry name" value="YALI0B05434P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ36492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="263" mass="30319" checksum="2662A3285F9BF3D7" modified="2011-01-11" version="1">MPKSSVMPSREDNTARSSSDYDEKFGLLDGVTSSHLAGASPRIRWALIFLALSNIATLCALFYAVLTPQPVPTTVVYPSQPDWFPPQIPVKKIFRSEPVFGQEPNNESIAAWNSLLPKGRGWVHMRNKTALPDMPGLNQSLPEHIALPSVYHQLHCLYSTMRSYYDVLDRINNPHQSRELPTDPGWNKEHLNHCWDYLRQNIMCAADVTLEWHRWNEKVETGWGYEHQCKDWDALTDWVLERRTSNNWGLLRGEGERIPLEDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0E2</accession>
    <name>E3R0E2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Erg28 like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_11713</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ERG28 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697440">
        <property type="protein sequence ID" value="EFQ36580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100600.1">
        <property type="nucleotide sequence ID" value="XM_008102409.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0E2"/>
    <dbReference type="STRING" id="645133.E3R0E2"/>
    <dbReference type="GeneID" id="24417077"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11713"/>
    <dbReference type="eggNOG" id="KOG3455">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114589_0_0_1"/>
    <dbReference type="OrthoDB" id="6485510at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016126">
        <property type="term" value="P:sterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005352">
        <property type="entry name" value="Erg28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15451:SF19">
        <property type="entry name" value="ERGOSTEROL BIOSYNTHETIC PROTEIN 28 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15451">
        <property type="entry name" value="ERGOSTEROL BIOSYNTHETIC PROTEIN 28-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03694">
        <property type="entry name" value="Erg28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="8" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="11" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="119"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ36580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="172" mass="19400" checksum="6340D685FE25BEEA" modified="2011-01-11" version="1">MPSYADYLPSAKGGILPYYMLLLSLISIGNSVQNLMTLHYSRRLYDGKYVRNTKLPARSATFNPEDSVDKYVPAPAGATDIIDQATPLAARCFGTWTFLTSIVRLYAAYHLRHAHMYDLAIWTYVVALGHFASELFIFKSMSFGLPQIFPFTLATTALIWMPLVRPFYVDSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0I0</accession>
    <name>E3R0I0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_11763</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697446">
        <property type="protein sequence ID" value="EFQ36618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100638.1">
        <property type="nucleotide sequence ID" value="XM_008102447.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0I0"/>
    <dbReference type="STRING" id="645133.E3R0I0"/>
    <dbReference type="GeneID" id="24417127"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11763"/>
    <dbReference type="eggNOG" id="ENOG502REFN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059577_0_0_1"/>
    <dbReference type="OrthoDB" id="341259at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF194">
        <property type="entry name" value="INVERSIN-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ36618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="319" mass="35341" checksum="08C01C9DE5EE5468" modified="2011-01-11" version="1">MPRQLPDNRVGVLMTAALSGDLALLSRLAGYVPHALRPLDTAQALSAAFYVPGSCPIHDNDDWEDRRPFATLLHVAAMRGDQDMTRWLLGRRVSIEASALLGCLCPSPYMNAICVTGVWSGWGIEPTPLHLSLVYGNKSTAKLLIRKGAVWDRPHTSCGGLTGLHMMAAGRMTEMIEWTIDQCHGPWAGVVARNGPVHDWPDEFGYWSLHYACLSERPKEEDESWAAQMVSGLIRLGALVHTTDGSRIAKRVSEERKRIQEGPRPRWTIDNQAAFDWAQRIQDWEEDGVVLESELALFAADCMQWGLAEAVAAVSKEDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0W9</accession>
    <name>E3R0W9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA recognition domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_11907</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697510">
        <property type="protein sequence ID" value="EFQ36757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100777.1">
        <property type="nucleotide sequence ID" value="XM_008102586.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0W9"/>
    <dbReference type="STRING" id="645133.E3R0W9"/>
    <dbReference type="GeneID" id="24417270"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11907"/>
    <dbReference type="eggNOG" id="KOG4660">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019467_0_0_1"/>
    <dbReference type="OrthoDB" id="417481at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007201">
        <property type="entry name" value="Mei2-like_Rrm_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23189">
        <property type="entry name" value="RNA RECOGNITION MOTIF-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04059">
        <property type="entry name" value="RRM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Mei2-like C-terminal RNA recognition motif" evidence="3">
        <location>
            <begin position="497"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="40"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="88"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ36757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="687" mass="76275" checksum="D6952E0B9338061E" modified="2011-01-11" version="1">MAHSRETDMFNPSSPRSSIGGAESFKGTPDTRLTAFSPEGGSTRSSRLLKSTSQDSLETTPSRYSTSAFGSVTSSAEKDPFIAVKPNSGHQKLSPTASTFQPFSCTPEKNRNHPTPDRNQQSLLPGQKYEAELSRSLSVCSPGRNLGIADLNACFAKLQRLGLSVQEPTQIQCKGGKLYVQFSDIRDAVLVRDNIHRVGAGYEADYLSDGDFYEHVHRESNNLDLWVSVVVVASPPGLLDVSRTEAVIKRMLDSQGQLSAFYVQHSYDPSVFRAFSQFHDPSRAASAVVSFDNKLVEVSAHSLSDIYVLHPEQNLTIDQGAHMTLSLVESSDISHMAQDRVATPDSLSHGMSGDLNNTLQALALSKPAPQMHMVPHSASMSGPNPPYSPFGIQVPPFAMWPILCQPQFQPHGPYLLNEGQRLPSAPAMSSPTAYQFSGPVFSHSSHTVSATGSMSPISRNESRRQGAARVNRSPYYNVASHHNHVDVNRIREGIDVRTTIMLRNIPNKVDQAMLKRIVDESSWGKYDFMYLRIDFANDCNVGYAFINFVDFVNTRGNQRWNCFKSDKVAEISYATIQGKDCLVQKFRNSSVMLEAAHYRPKLFYTSNGPVPGLAGEEEPFPQPDNQSKMKRSCENAEHVGLFTPNAGQHFRDEQRRRRSQYDRGTRLAALEEHDLDASMQLYIYHSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3R117</accession>
    <name>E3R117_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyl hydrolase family 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_11951</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glycosyl hydrolase 12 (cellulase H) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697558">
        <property type="protein sequence ID" value="EFQ36805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100825.1">
        <property type="nucleotide sequence ID" value="XM_008102634.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R117"/>
    <dbReference type="SMR" id="E3R117"/>
    <dbReference type="STRING" id="645133.E3R117"/>
    <dbReference type="GeneID" id="24417314"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11951"/>
    <dbReference type="eggNOG" id="ENOG502SH4Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051064_0_1_1"/>
    <dbReference type="OrthoDB" id="89349at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013319">
        <property type="entry name" value="GH11/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002594">
        <property type="entry name" value="GH12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34002">
        <property type="entry name" value="BLR1656 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34002:SF10">
        <property type="entry name" value="PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01670">
        <property type="entry name" value="Glyco_hydro_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179046" evidence="3">
        <location>
            <begin position="19"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ36805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="238" mass="26459" checksum="2618C94E1C27D280" modified="2011-01-11" version="1">MKIYNYLVVGIFGPLALAQSLCDQYGYYAQAGYYFNNNRWGQGSGQGSQCLTVSWANSDGVGWKTDWTWSGSPNNVKSYPYSGITMSNKLLVSQIGYLGTSASWQYSNTNIRANVAYDLFTAADPRHDPSSGDYELMIWLGRFGDIQPIGSSQGRVTVGSRSWDLWYGVNNGMRIYSFVASSPISQFNEDVKPFFTYLQNSKGFPASSQYLITFQFGTEPFTGGPTTFTVSNWNAKVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3R168</accession>
    <name>E3R168_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_12002</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697689">
        <property type="protein sequence ID" value="EFQ36856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100876.1">
        <property type="nucleotide sequence ID" value="XM_008102685.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R168"/>
    <dbReference type="GeneID" id="24417365"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_12002"/>
    <dbReference type="HOGENOM" id="CLU_151422_1_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045634">
        <property type="entry name" value="DUF6413"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19951">
        <property type="entry name" value="DUF6413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003181021" evidence="1">
        <location>
            <begin position="21"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="92" mass="9495" checksum="A1A9F55515FFA983" modified="2011-01-11" version="1">MHASTVLFVSLSLLAGQVLATGRCCNGGTDDFQNFCKSSNLNSFCCTTRDPNSGRGCDGDTEFPTGRDTKIDGVPFAPSCTSGGQTGFVACA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q381</accession>
    <name>E3Q381_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">A49-like RNA polymerase I associated factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_00204</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089080.1">
        <property type="nucleotide sequence ID" value="XM_008090889.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q381"/>
    <dbReference type="SMR" id="E3Q381"/>
    <dbReference type="STRING" id="645133.E3Q381"/>
    <dbReference type="GeneID" id="24405569"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00204"/>
    <dbReference type="eggNOG" id="KOG4183">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034953_1_0_1"/>
    <dbReference type="OrthoDB" id="532500at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009668">
        <property type="entry name" value="RNA_pol-assoc_fac_A49-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14440">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06870">
        <property type="entry name" value="RNA_pol_I_A49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ25060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="440" mass="49116" checksum="E623DD7F37F3C190" modified="2011-01-11" version="1">MSDANGRKRKRDLDRPSKSKNKLATELSIVSVSSVLRPQLCPPVIASAPGVRLPRSVPFSPYVKQDISSSKRRQKVPAVSQDLVLHSTSHQTMDYTAREDGISDSQQALKHYVGIYDPNTGALQVVEAKKMVVRGVARAKHASEEAMRAPADNQSYYDQKKDLGQTFGTKKAKKAIESVALNAIDPNKSRDSAPKKLDAASKAIMQEIGGVTANMTSREQLQAAVDKAKPVPRPNLEAEAIQDVYDPDEFIGREVLAAVPIKDWVEPTKSGEEVLCYSRHVAARVKKVADSGSVSKMRLLRYFYFLFTFYTMATPGKQRGTKRIPPRDKLKERLSPAPQVVIEHIRRKFSDGGEMRKFHMDMLITHCCALACIIDNFEVDTSLLRQDMRLDQKEMNNYFYEIGAKVKQVATKEPGKAAHVAKLALPLNFPKLRSVAPKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3D5</accession>
    <name>E3Q3D5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">TEA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_00681</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TEC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089557.1">
        <property type="nucleotide sequence ID" value="XM_008091366.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3D5"/>
    <dbReference type="STRING" id="645133.E3Q3D5"/>
    <dbReference type="GeneID" id="24406046"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00681"/>
    <dbReference type="eggNOG" id="KOG0110">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009126_0_0_1"/>
    <dbReference type="OrthoDB" id="10006572at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.20.40">
        <property type="entry name" value="TEA/ATTS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000818">
        <property type="entry name" value="TEA/ATTS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038096">
        <property type="entry name" value="TEA/ATTS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050937">
        <property type="entry name" value="TEC1_TEAD_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11834:SF0">
        <property type="entry name" value="PROTEIN SCALLOPED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11834">
        <property type="entry name" value="TRANSCRIPTIONAL ENHANCER FACTOR TEF RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01285">
        <property type="entry name" value="TEA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00426">
        <property type="entry name" value="TEA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51088">
        <property type="entry name" value="TEA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TEA" evidence="8">
        <location>
            <begin position="126"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="TEA" evidence="6">
        <location>
            <begin position="126"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="566"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="854"/>
            <end position="891"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ25537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="927" mass="104024" checksum="1420F64614C02365" modified="2011-01-11" version="1">MEHPRPMLPSQRYSPSPVYSYDSRRCTPTGRQPLKESNGNAQPAGSHLGSLASSCRNSPLGLFSPSFTGIPTPPIVPSQAGVDYRTSGSIRRPDALQMARRARPDINPIYYAPEFRPYRDKQDQKDPNEKQIWPRVLEDAFLDSLLIIPHMGRKKYSMQGKQFGRNMLISEYLWIAYCDSLQPGQKAEERKRKQVSSHIQVVKKMFEKHRCYHFFFVKDPDKSEARLKDNMEVASFKDNPVLIALAEGRLPDVRPNYKYFAQILAMDSLVVMRPKTAWIFVASNNVRMDEDGEIYDHHGKPLDKSYYPHLEKNMHKEDGASRGLNGSILLHEYNKELSQKESAAVTELAQEWETKFPALHESLEFAIRDNKWLDILEMTVTLEIHPRSNFPAGSELNGFVELSISLPALQNHRWKCVTKLARPEELRRAETDRLIVEQTSEVGIQYTHRPGCQENKFECDCRSRPRQDVRVPFPAAEWASILSTCAGYLEPAENKAKIEDDEDRSKAAEDAAIEAERTTAELIQQVGMFQELWSIPPDSSDRRAWTRRGIILWKFRTIHAFDDKWNPIFEKPVPPKGRKPADEEDEEQGTSSRRGGRSKRVFNPPGTTWRFLTALDPVSSAHQQNVCINPAAAPGRDMLMAPTPPYSHQLAAVMNDNLTSAWDPVSMSGQLPSLASTGTLGLMDNFSHGLATPPPTASIHSSYASSYDGSHELASGSHHHHHQLDFLAAACTSSMDSQSTLVTDMGPASADPFLSATGGIQVSNGVGVGVYDEGEVEGISDWDTATSSFHSLNHWNGWNETSDTKTHQWQNENQRSAAANANLWTETKDHHQTWNQQPWAQAVSAVAAVAGTDGRSGWSPVDQQRGLPSLDQITPLKPMSGMKRARSNSLDMENRENYPATAIQKLVHHRAPAAVMDESGHGHRSWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3M3</accession>
    <name>E3Q3M3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SAC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00769</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089645.1">
        <property type="nucleotide sequence ID" value="XM_008091454.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3M3"/>
    <dbReference type="STRING" id="645133.E3Q3M3"/>
    <dbReference type="GeneID" id="24406134"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00769"/>
    <dbReference type="eggNOG" id="KOG1889">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003016_7_4_1"/>
    <dbReference type="OrthoDB" id="405996at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032541">
        <property type="term" value="C:cortical endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005797">
        <property type="term" value="C:Golgi medial cisterna"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072517">
        <property type="term" value="C:host cell viral assembly compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017059">
        <property type="term" value="C:serine palmitoyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052629">
        <property type="term" value="F:phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004438">
        <property type="term" value="F:phosphatidylinositol-3-phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043812">
        <property type="term" value="F:phosphatidylinositol-4-phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061909">
        <property type="term" value="P:autophagosome-lysosome fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002013">
        <property type="entry name" value="SAC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45662">
        <property type="entry name" value="PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45662:SF2">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-3-PHOSPHATASE SAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02383">
        <property type="entry name" value="Syja_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50275">
        <property type="entry name" value="SAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="593"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="626"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="domain" description="SAC" evidence="2">
        <location>
            <begin position="118"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ25625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="704" mass="79111" checksum="811875694388C858" modified="2011-01-11" version="1">MAPTLPYRDINVKVAPDSYVFTSPSSPDAPALVIDRPTGDLRLGDAGQSKRVSRVSSIAGILGIVQLRLDKYVIVITKANPVGRLKGHMVYKVVATEILPMRERQIRDPDEDTFIGLLDTFMKNGPMYFSYSIDLTNSFQRQASADTSLPLWQRADDRFFFNRFIHSDLVDFRTKGARGHPGPQPAVDPFILPVIFGMLEIRPTTFKGTPVTVALISRRSRHRGGTRYFTRGVDDEGHAANYNETEQIIIFNDSGSAMGGFAGSSDMQSGKYGGAPAAGSETQIMSYVQTRGSVPTYWAEINSLRYTPKLQVRGIDSALPAAKAHFEEQIRIYGDNYLINLVNQKGREQRVKASYEQMVEKLVSSPNERTEGDRITDEKFTVIQPEKRAVEFDRLHYVYFDYHHETKGMKMHRAYALVEKLRDALDAQGYFRAVDMPAAAANDGRLEPRAFQTSVMRTNCMDCLDRTNVVQSMFARHMLDRIFEDMGLMARGSSFRDEDPAFEHMFRNLWADNADVVSCSYSGTGAMKTDVTRTGNRTKLGALQDARIGVTRYFKNNFFDGPRQDSYDLFLGVYSPGTANIGGALVFADRRPILIQSVPYLLAFSVFLVLVGLFSKTDAVVTIRVFILFWLAVAAWCASFIFGHGMLYVNWPKLNPRPWANDGYAEHMSKARKDSVLGSFVAHHERGLSTARYLNAEEGKKRIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3P0</accession>
    <name>E3Q3P0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Fungal specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_00786</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089662.1">
        <property type="nucleotide sequence ID" value="XM_008091471.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3P0"/>
    <dbReference type="STRING" id="645133.E3Q3P0"/>
    <dbReference type="GeneID" id="24406151"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00786"/>
    <dbReference type="eggNOG" id="ENOG502QTSE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015811_1_0_1"/>
    <dbReference type="OrthoDB" id="2154091at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF81">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="8">
        <location>
            <begin position="264"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="565"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="579"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ25642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="667" mass="74987" checksum="51CE60CC77896DAA" modified="2011-01-11" version="1">MPAEKAPRGQIRCSRTFPCTSCSSALAKCEFRESDFKRPPVSRENVATLESRIASLESLVGRLKTADSDERNRILDDLEDQDYVPSFSSLPLEDEIALSEAMTKASFQEMTDGSLIYHGPTSIYQNEASSPAYPPTSSPTVSKPSFVHENREVLVNDTMRLCIGLFFHWQYPVVMFIDRESFIQEYEANPVNGNYCSPPLIYSMAAIGALMSRDPDVKAKSPGFADTAQSILMTIEFGVSRPTSVQAFLCLSYYETGVGNMSKAWVYTGIAYRMCQDLGLQRDLAHWSPDAKSNLSSPFPFNNEFRRRVYWGCFLSDKMFSLFLGRPTFLLDPPIWDNWLQAHGLGFLQTGQPGGPRLTPWFNQMLELGRIVHDMLSKTFAPKKMKDPSARRWNELSLSKLNARLVAWHEALPSEMRWKKWTTNKDVLQPHVACLHTFYHSTRICLNLPFITSVRQIPSVPDGEAEDLTNPIIKSFIICQSSAQRIVDVLQRFRAQHTLENTPLNFIGATILATNAVLATTRRQSSPPSLLKDTLLPFLDSALEELSSSWKLAGEARQKVRNALNLAQVRHPQSPVRTRQPDRATDGKDRACDQPPVVNPVEAQASADPPLEKSSGPEETVLDPMGLLDSEAAYWGGYRNDMVDVWDANFVNHLADADWLNQPHMPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3W3</accession>
    <name>E3Q3W3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_00859</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089735.1">
        <property type="nucleotide sequence ID" value="XM_008091544.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3W3"/>
    <dbReference type="GeneID" id="24406224"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00859"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_1_1"/>
    <dbReference type="OrthoDB" id="3639251at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000057">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF49">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G04250)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="157"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="220"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="294"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="330"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="354"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="380"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="408"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="451"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="55"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ25715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="494" mass="54081" checksum="A071441AF24E4CEB" modified="2011-01-11" version="1">MDSTLDTKGSRAPDRSDIESAAVKEYFSPASPPQSDAPSDDEEEKALLWKQDKRIIPLSAGIYFLCFLDRSNIGNAKILNSSTRHDMQTETHMSNRDFTIALMVFLIAYAVFEVPSNILLKKLRPSRWLSFLMFSWGTVTIGLGGATNGAAVTGVRFLLGVFEAGLFPGLVYYLTFFYKHNERSVRVAMILASATLAGAFGGAIAYGIGHMNQVHGMSGWRWLFILEGIPSCLSAILVWAYLPDYPETAGWLSEREKDVARQRLYYEGSKSSDKSMSWEEAKVTLTDWRLYGHYAVYFAMSTPFSSLSLFIPSITAGLGFHDLQAQLMTVPPYAAAYVVQILVAWSADRLNARGAHSAALALIGGIGFLISAVLPPDAYHARYGCLIVGASGAFACIPPLLGWLSSNVFSTGATGLAIALNVSFGGGLGQIPGVWTYKAEEKTKGYPTGHWVNAALLFVVVVGCAWLRIYYGVKNRQILRRAAEDGTHPRLYKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q407</accession>
    <name>E3Q407_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_00903</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089779.1">
        <property type="nucleotide sequence ID" value="XM_008091588.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q407"/>
    <dbReference type="GeneID" id="24406268"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00903"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_13_1"/>
    <dbReference type="OrthoDB" id="6133115at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000217">
        <property type="entry name" value="MFS lactose permease, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF13">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="298"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="331"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="359"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="401"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="442"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="472"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="48"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ25759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="534" mass="58586" checksum="FFE971AC1CA1B500" modified="2011-01-11" version="1">MSEKIDAVDTVHKEIETRVVTGSEAFNEAMIKEPPKAWSKPQLFIYAFSLVGFFCSTMNGYDGSLINNLLQNPSFKERYGAKNDGIWAGIISSMYQIGGVIALPFVGPALDTWGRRIGMLIGAGIIVIGTCVQATANGTSQFMGGRFLLGFGVSIAASAGPMYVVEINHPAYRGVVGAMYNTLWFSGAIIASGVARAALDIEGDASWRLITWMQALFSGLICLFCMWMPESPRWLFVNNKKEQAAAILAKYHGNGNTDSPWVKLQLHEYEELLNMDGADKRWWDYRALFRDRASIYRLSANVCISIFGQWAGNAVLSVLDTAGYTHPIQQANITLINSCQQFAFAIFGALLVDRVGRRPLLLFSFAACTFVWLGMTVASGILSKSQIGETDGGSPIFDNPAASQACLAMIFIFGSVFSVGITPLQALYPVEVLSFEMRAKGMAFSNLAVNAAGLLNQFAWPVSMEKLAWKTYIIFTIWDAVQTAVVFFFIPETKGRTLEELDHIFADPNPVKASIRKKAVAVDRYGDVVNVQDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4E1</accession>
    <name>E3Q4E1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF7732 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_00597</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089473.1">
        <property type="nucleotide sequence ID" value="XM_008091282.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4E1"/>
    <dbReference type="STRING" id="645133.E3Q4E1"/>
    <dbReference type="GeneID" id="24405962"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00597"/>
    <dbReference type="eggNOG" id="ENOG502S4KZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060392_1_0_1"/>
    <dbReference type="OrthoDB" id="5425547at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056634">
        <property type="entry name" value="DUF7732"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42091">
        <property type="entry name" value="CONSERVED GLYCINE-RICH PROTEIN (AFU_ORTHOLOGUE AFUA_7G02440)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42091:SF1">
        <property type="entry name" value="CONSERVED GLYCINE-RICH PROTEIN (AFU_ORTHOLOGUE AFUA_7G02440)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24866">
        <property type="entry name" value="DUF7732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179398" description="DUF7732 domain-containing protein" evidence="3">
        <location>
            <begin position="19"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="171"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7732" evidence="4">
        <location>
            <begin position="153"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF24866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ25453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="312" mass="30502" checksum="73778066116C73AE" modified="2011-01-11" version="1">MRLDLAVVALTLCVPTWAVAVDTGLHGSDVAFLAPKAERDNSQSDEKLWKRKGGGGGGGRGGGTSGGSRSGGSKSGGSSGGSSGGSSGGSSTGGSSSGSGSGSSSRNGGSGSGGSRGGTGGGSSSSRGRAGDNAGGSTRSGSGPPPAYGGGRYYGGGAAVPYRAGAARGSILPFVLVGGALAFWPGLWLAGAYMYPYSHPYRYYNETARENQTKAVLCGCAEDLPCGCEENNATDYMNSLLGNGSYDGLNKSVVNIGEVNGTETILINGTLPSGTTASGGTDEVGSAAFRTAVETLGFWPVAAVVLATVFAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4F2</accession>
    <name>E3Q4F2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">U3 small nucleolar RNA-associated protein 11</fullName>
            <shortName evidence="6">U3 snoRNA-associated protein 11</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_00608</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Involved in nucleolar processing of pre-18S ribosomal RNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the ribosomal small subunit (SSU) processome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 6">Nucleus</location>
            <location evidence="2 6">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the UTP11 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089484.1">
        <property type="nucleotide sequence ID" value="XM_008091293.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4F2"/>
    <dbReference type="STRING" id="645133.E3Q4F2"/>
    <dbReference type="GeneID" id="24405973"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00608"/>
    <dbReference type="eggNOG" id="KOG3237">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061887_0_1_1"/>
    <dbReference type="OrthoDB" id="29058at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007144">
        <property type="entry name" value="SSU_processome_Utp11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12838">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12838:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03998">
        <property type="entry name" value="Utp11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015952">
        <property type="entry name" value="U3snoRNP11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="173"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="247"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="144"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="176"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="258"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR015952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ25464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="270" mass="30700" checksum="B23EC55E0327732C" modified="2011-01-11" version="1">MSSMRNAVQRRSHRERAQPLERQRFGLLEKHKDYSLRAKDYNKKKAQIKSLRQKAAERNEDEFYFGMLSRNSMGSRVKDGRKWSGTVAGDRGNKAMDMETVRLLKTQDVGYVRTMRNVISKEVKRLEEQIVLVGGIEAASHNDDDADHSDDEIDTRPAAPRKIVFLDGAEAKADAAQEEAMDLDGEEDDEDEFEGFDDDDNKDADDDVQAQKEKALQRLRLQLQNAKKKLKVLAKAEEGLEIQRAKMAKTATSGGTTKKGKKIMVRARKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4Q6</accession>
    <name>E3Q4Q6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_01215</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ26071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090091.1">
        <property type="nucleotide sequence ID" value="XM_008091900.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4Q6"/>
    <dbReference type="STRING" id="645133.E3Q4Q6"/>
    <dbReference type="GeneID" id="24406580"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01215"/>
    <dbReference type="eggNOG" id="KOG0586">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019271_1_0_1"/>
    <dbReference type="OrthoDB" id="410920at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000640">
        <property type="entry name" value="Serine/threonine-protein kinase PRR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF30">
        <property type="entry name" value="MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="360"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="60"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="264"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="312"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="60"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="129"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="339"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ26071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="699" mass="76399" checksum="ADF40F97156BB3A7" modified="2011-01-11" version="1">MSNRPPQSMSLHTQQPQNKVDGISDPVASDTNIHHNAAAPFTDISFSYVSNPQIQFQANTIAPSPPLSESSFQHLDPPSTQTLVSTQSAPTSSLRIQTTHFHTHLPTGPDNRPNATLSTPRRPSAAVLQHQTSSSSLKPVSRTPSFKAAIANSLGPASATSSCMTSPILSAMSDVTPLPSPLLSGDSPGPWKRLGLRSPSRHQMPDPTPDSVLVSATGESIAAALANASKRKVYAGLVSEGADGAGANGPVTGKAEHARNRSISEYTPDSNYVPKRHVTVSGSHTKPANGPDANNEPHMRRELNLAESRGLTPAIAQPPTPPPSESSRDPTDTAASRPTKSENTEYFEAYDRRDRKKRRWRAVKTLGQGTFSRVMLATSQLDDDDNLAQAGGPASISQMSQPFRKTLVAVKVCEHGPRGGASEERIEMSLKRELEIMQSISHPSLVHLKAWNIEPSRAILVLSHCPGGDLFDVATGHRQLLKPALLRRMFAELVGAVRYLHERRIVHRDIKLENVLVNLTAPELADPATDWTTYPHSVITLTDLGLSRRIADDEKLETRCGSEDYAAPEVIMGLPYDGRATDAWSLGVLLYALLEARLPFDPYPNTMDGHRMRSRTSHRIARAEWRWIEFAGKDGDHEGDEAKFKELGLLGAMEITEGLLQRARSRWTLEKVAEHEWVKEAIQVEGGLRFREEVEGAEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4Y6</accession>
    <name>E3Q4Y6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Structural maintenance of chromosomes protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_01295</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SMC family. SMC1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ26151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090171.1">
        <property type="nucleotide sequence ID" value="XM_008091980.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4Y6"/>
    <dbReference type="STRING" id="645133.E3Q4Y6"/>
    <dbReference type="GeneID" id="24406660"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01295"/>
    <dbReference type="eggNOG" id="KOG0018">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001042_0_1_1"/>
    <dbReference type="OrthoDB" id="5575062at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008278">
        <property type="term" value="C:cohesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007062">
        <property type="term" value="P:sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03275">
        <property type="entry name" value="ABC_SMC1_euk"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1060.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024704">
        <property type="entry name" value="SMC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028468">
        <property type="entry name" value="Smc1_ABC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010935">
        <property type="entry name" value="SMC_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036277">
        <property type="entry name" value="SMC_hinge_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18937:SF12">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18937">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06470">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005719">
        <property type="entry name" value="SMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00968">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75553">
        <property type="entry name" value="Smc hinge domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0498">Mitosis</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC hinge" evidence="13">
        <location>
            <begin position="541"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="77"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="677"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="751"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="192"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="436"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="1052"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="81"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="685"/>
            <end position="697"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR005719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ26151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1253" mass="143599" checksum="138F0A851E3EC59C" modified="2011-01-11" version="1">MGKLIRLELFNFKSYKGHHILLFGDSYFTSIIGPNGSGKSNSMDAISFVLGIKSSHLRSAHLKDLVYRGRVLKTSRIQDDGSAQSNGQSNGDGDDLSQKASRSDPKTAWVMAVYEDDAGDEQKWKRSITNQGSSEYRINDRVVTAQQYNEALESENILIKARNFLVFQGDVEAIAAQSPQDLTRLIEQISGSLEYKGEYERLQTEAEQAAENQSFQLHRRRGINSEIKQYQEQKKEADNFQKKTEERDEAIVKHALWKLYHFQRGMDESTEKIQDHQQNLQEFQRNVESFRKKLEAAQKEQQAAAKQVHGVEKAINAKKREFDELEHKLIPIDAKIEEKTRNIEQCRSRMEPVRKERDKQAELIKEDEGRLKTTEKAQKHFESQLKERMKKLGKELSEDDRKEYNALRSQVVQRCAGNQARLDNLIRQQKTDEVTVNTLKGKVDTLSAALEKYEGELETLGERKASTEGNIKALSQEIDTKKKQYHQIQSERVRTSQRRTELEEKLETVAKQLREADDGRRQNDREARMKEMVNNLKRLYPGVKGRVGDLCKPKQKKYDEAVSIALGRDYESVIVDTEKTGHECVQYLKDQRFPPMTFIPLDNIKVNAVNGAIKGISGARLTIDTIDFDAAYERAMAYACGSSVVCDNEQVAKLISYERRIPVKTVTLDGLVIHKTGMMTGGRGPEPKGGKRRFESSDLDSLKKMAAKYKEEIEKLPKSGRRSTAEESLQTEIHGLEPRLANAKAELAHLEKNYDSKKRERDNEERQLNELQPKYEEKTAELEATKRTVREFSDAIAKVEDEVFSGFCRRLGFSDIRAYETEHRDMQREADEERAKFEVQKSRFQSQLTLARDMHSNLEKRLRKLQEALKAAERDLQTFQQEKSDIEDATHEVSDELDALSETLEEYRGKLEEKNQKVSQAKAEVHKRSKEIDARQKEINALETVVQKNSAGKFALLRRCKLEQIQIPLLEGSLDNLPNEDNMLRQDADAMDVDEEVDDEDMMTAALENYGIEVDYDSLDEEMKNSDDASVEEKLLDKIASLTSELEKLNPNMRAIERLESVESRLKNTEKEFEESRAALKAARDAFNHVKAQRYELFNKAFTHIQEQISHVYKDLTRSEAYPLGGQAYLDIEEDTDTPYLSGIKYHAMPPLKRFRDMEHLSGGEKTMAALALLFAIHSYQPSPFFVLDEVDAALDNANVDKIKKYIREHAGPGMQFIVISLKTGLFQDSESLVGVYRDQEVNSSRTLTLDVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q505</accession>
    <name>E3Q505_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sucrose transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_00915</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089791.1">
        <property type="nucleotide sequence ID" value="XM_008091600.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q505"/>
    <dbReference type="STRING" id="645133.E3Q505"/>
    <dbReference type="GeneID" id="24406280"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00915"/>
    <dbReference type="eggNOG" id="KOG0637">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_555487_0_0_1"/>
    <dbReference type="OrthoDB" id="28755at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008506">
        <property type="term" value="F:sucrose:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19432:SF35">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 45 MEMBER 3 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19432">
        <property type="entry name" value="SUGAR TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="342"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="366"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ25771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="467" mass="49429" checksum="A8FDD7919FE9D7C1" modified="2011-01-11" version="1">MKSFEPLDLAVEVPLVEMDKTTSSSTLDDGSERSTVSACPGAADEHPRVSIWRIVCYAVPSLPIQSFFTMFTVYLIPYLIGELGFTAFQVALVLLAGPLSGLTASPVFGVLSDRSGRRFVFYKFGSATMTVCQLALGWSREIVGGNMVAARWLSTVTIYLGCVGVRACIISHRALTIANIPPQQQPVYTLASGLMLASGAIITLVAGLIDPDFRLISTICATGIFLSILPLWAVQSDAYHSPVIVHRESSNVIASVLSVPRAMWHASKCLPPTIRHSATHGPASEAAPPDVISRAGVRVFLIAQLGALMLQTSIVRSWDTSVASAGRLRQFMKEDVMVLRRVWALSFATLGISTAGAIVFRASFMAASVCAASIMTLSPLSGWVPFAIIAYEASVVQREQGSAALQAIPGTISSIHEIAITSGQGVSVAVNAIISFGLDHFQAGGENSTAFLFPPAVAAALVGVLIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q551</accession>
    <name>E3Q551_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_00962</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089838.1">
        <property type="nucleotide sequence ID" value="XM_008091647.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q551"/>
    <dbReference type="GeneID" id="24406327"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00962"/>
    <dbReference type="HOGENOM" id="CLU_2026547_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ25818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="122" mass="13516" checksum="502ED0891A351112" modified="2011-01-11" version="1">MLRSGHTAHPEPGISLPAKTFISDLNKQVLISPTMPPFPVLVPIENDMDLVELILALDRPWPSPPMEGATSDGLGRFEYLVRSTPSLLAQRLMPWNVERLAAVAPPRPRARPPVKTIRQPVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5F0</accession>
    <name>E3Q5F0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">GMC oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_01061</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089937.1">
        <property type="nucleotide sequence ID" value="XM_008091746.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5F0"/>
    <dbReference type="STRING" id="645133.E3Q5F0"/>
    <dbReference type="GeneID" id="24406426"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01061"/>
    <dbReference type="eggNOG" id="KOG1238">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002865_6_0_1"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF115">
        <property type="entry name" value="DEHYDROGENASE XPTC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180082" evidence="5">
        <location>
            <begin position="18"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="108"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="7">
        <location>
            <begin position="289"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="542"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="585"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>FAD</name>
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        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EFQ25917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="608" mass="64997" checksum="CC3DF80C5CE903CE" modified="2011-01-11" version="1">MLVKACLALASAAIVSGAPSLTRSYGDDVYDYIVVGGGTAGVAVAARISEGLPAAKILLIEAGPAVWDEPKINIPGMKGSTLGTKYDWNFTTVPQPDAKGRTFAVNRGKVLGGSSALNLMTYNRAAVAEYDSWEALGNPGWNWETMIAAMKKSENFTGINTDTYGSEGVGDSGPVKAVINRIIPKQQETWIPTMNSLGIKTNLESLGGNPLGVMYQPSSIDPTHYNRSYSANAYVPIAGPNLVILPDTTVAKVNLEKDTAKSTLQRACGVTLQDGTVIQARKEVILSAGSIQSPGLLELSGIGQASVLEASGIEQVIDLPGVGENLQDHLRIQSSYQLKPNYTSFDILRSNTTVAAEQLALWNAGQVSLYDYTGSGYTFSTWAQAIGNDSHLVNLAKQAAGEDSSVVDHKKLEFLSDPSIPQLEVIFSDGYTGVKGYPAATSPLFGKGFFSLIAVLMHPMSRGSIHINPSDTAGKPIIDPNYFSHEHDLEAAIQAIKYCRKIAQTEPMKQLWENEYEPGLDAVQTDEQWKQFALNTTLSIYHPVGTCSMLPKEDGGVVDADLKVYGTSNLRVVDASVIPLLISAHMQTAVYGIAEIAAERIIASAATC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q625</accession>
    <name>E3Q625_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_01417</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008092102.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q625"/>
    <dbReference type="GeneID" id="24406782"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01417"/>
    <dbReference type="HOGENOM" id="CLU_1758662_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ26273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="148" mass="16152" checksum="09F2D8A120007253" modified="2011-01-11" version="1">MSASDLVAQPAPDPPIYRPVQSIKGTGASRFVLLSQTIPNHLINDNRHAGIHGSPVAPSRVAVFAPSPNHGCLPVLVTSESQSPDFWAKRRLMEEQSSTKQSAHLRTPHIDSAGDAWLSPFRLPTPLPRRILPRVPCRPVARSPVRIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6J8</accession>
    <name>E3Q6J8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA recognition domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_01590</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090466.1">
        <property type="nucleotide sequence ID" value="XM_008092275.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6J8"/>
    <dbReference type="STRING" id="645133.E3Q6J8"/>
    <dbReference type="GeneID" id="24406955"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01590"/>
    <dbReference type="eggNOG" id="KOG4210">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026791_2_0_1"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051945">
        <property type="entry name" value="RRM_MRD1_RNA_proc_ribogen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN 14B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039:SF5">
        <property type="entry name" value="RNA-BINDING PROTEIN 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="227"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="333"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="301"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="415"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="59"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="109"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="136"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="167"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="186"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="316"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="420"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ26446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="474" mass="49206" checksum="BE377CC25E9B50E8" modified="2011-01-11" version="1">MGKTKSTTKGSKAADPITKVKNAGVTKATESPKAKSKAVAKEAAAKEKSSKKTKKVVEPESDSSDSSEEEEDSDSSESEAEASSDSSDSEEEKPVKKAAPKAAKKAESSDSDDSSDSEEEAPKAKTNGAAKKAETSDSDDSEEDSDDSDSSEDEKTEKKAAATSDSSDSDSDSGSDSDSDEEEDSSDSKEASETEAKTEEPSKKRKALDDPVIPGKKARTDVSDKSSTLFVGSLAWAVDDNSLYEAFQEFADLTGARVVTDKATGRSRGFGYVDFATPEAAAAALEGSQGRELAGRAMNIDFSGQKPAGDGNHQARASDRAQRHGDTVSPESDTLFVGNLPFDVDQDTVNAFFSTAAEVTSVRLPTDPETGNLKGFGYVSFNSIDDAKTAFAQLNGQYVGEGRSGRAVRLDFAGQKPQREGGGFGGGRGGGRGGGRGGFGGRGRGGGGGRGGRGGFSSTNRGGFGDFKGQKVKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6L6</accession>
    <name>E3Q6L6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">SH3 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_01608</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090484.1">
        <property type="nucleotide sequence ID" value="XM_008092293.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6L6"/>
    <dbReference type="STRING" id="645133.E3Q6L6"/>
    <dbReference type="GeneID" id="24406973"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01608"/>
    <dbReference type="eggNOG" id="KOG3655">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013085_2_0_1"/>
    <dbReference type="OrthoDB" id="5971719at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030864">
        <property type="term" value="C:cortical actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030427">
        <property type="term" value="C:site of polarized growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11281">
        <property type="entry name" value="ADF_drebrin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11962">
        <property type="entry name" value="SH3_Abp1_fungi_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11961">
        <property type="entry name" value="SH3_Abp1_fungi_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000242">
        <property type="entry name" value="Actin binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000273">
        <property type="entry name" value="Actin binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.20.10:FF:000045">
        <property type="entry name" value="Actin binding protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035719">
        <property type="entry name" value="Abp1_fungi_SH3_C1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035718">
        <property type="entry name" value="Abp1_fungi_SH3_C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002108">
        <property type="entry name" value="ADF-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10829">
        <property type="entry name" value="CORTACTIN AND DREBRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10829:SF25">
        <property type="entry name" value="DREBRIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14604">
        <property type="entry name" value="SH3_9"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00102">
        <property type="entry name" value="ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51263">
        <property type="entry name" value="ADF_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="ADF-H" evidence="5">
        <location>
            <begin position="5"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="628"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="715"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="195"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="277"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="371"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="687"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="243"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="334"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="414"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="514"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="563"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="585"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="705"/>
            <end position="723"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ26464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="773" mass="81735" checksum="D228DBAC8C5CBFA4" modified="2011-01-11" version="1">MASLNLSINGPSIKSSYQGVINSALPKSSSPTYAQWALFSVQAPLANAFQDSGSKESVLKVQSTGDGELSDLIEDFNEGRIQFAFVKVKDPNSGLPKNALIAWCGGGVPERTKGYFTTHTAAVSKILHGYHVQITARSESDLEPESVMRKIADASGAKYSAGSSTTSAAPPPVASKPVFTPTTSSVGNVNPIVAARNRKTANPDDDGWGEDAPPVTRSQLEKVESAYKPTKVNMAELTKQRQEPSSSNGGNSQGRPDVVRGAYQPVGKVDIAAIRAAAKNQNDDRPTPVKGSYEPVGKVDIAAIRARAQKPSEPVEQEPADDERPKSLAERSAAFSQSQSERLTSLPKPKVASKFGAAAAFTGTKAPTPGGLGFGAPSVPAPPPVGAASRTFADQGGKTPAQLWAEKKGKQGGSVSNTVSPPVTSPIGVQKSGEWKSGYAGKSWGPVKTAEYGRGSLSQENTGEDPQERSVGAPASPSGGVGALRDRFKDAPPISGGAPSIPREQHREEEDEPSPPPPPSGSRPPPAGGFALPGLPSRPAAAQEEEEEEEPQSPIRVAQPVARGHEVDMEPPMEREPPRPIPTQEIERELPREEELSDERVDVGRGAAAAVAEHEFGQEQVAAGQASSGGKRALIQYDYEKAEDNELELREGEYVTNIEMVDDDWWMGTNSRGESGLFPSNYVELVDDEPEPAPAARSAPPPAPAQAEPAPAAAGGGRTATAQFDYEAAEDNELSFPENATITDLEFPDEDWWFGSYGGKQGLFPANYVQLDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6Y7</accession>
    <name>E3Q6Y7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02445</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090645.1">
        <property type="nucleotide sequence ID" value="XM_008092454.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6Y7"/>
    <dbReference type="STRING" id="645133.E3Q6Y7"/>
    <dbReference type="GeneID" id="24407810"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02445"/>
    <dbReference type="eggNOG" id="ENOG502RPDK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045008_0_0_1"/>
    <dbReference type="OrthoDB" id="3469466at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910:SF6">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="23"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="429" mass="48408" checksum="7D1503015ABAD6A1" modified="2011-01-11" version="1">MTPRRPHLELFNPTYPNAGHRSFSLFAQLPTELRVLIWQYSLQRHRMIHIVLEKRVETGASNETNIAERYSLLNGLGRPVSGNHYKVVTPNRHVLLPDNIMMVNKEAQAVVLAFYPVHIPCYLKSCVDMEGKSPMLRLNLDWDYLRISADNALSLFFDFLHDLRAYDPGGHGLRHLVVEDNHFRIAEMPSLSPASLDARALAAFKATLAALKTIWFKNTPPGGRGLDVLTWIRANIFNYGFPVFPAFTFFEPPRPDSRDVSRDLRNVGGSVPDWREMPLGWRMLLRRLGISPEDVEGAPGVDVRVMVASDREGDIRTREDAARALHEEDFGWLQLQWWFRGWDSPRPGGGGDRPAGCFATASGLRPSLPELDGPKVLAAAPRPALGFWLFPVDAFGEIPEEEDPPLWIRSKGIFDLSSHWPDLALVDVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6Y9</accession>
    <name>E3Q6Y9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HNH nuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_02447</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090647.1">
        <property type="nucleotide sequence ID" value="XM_008092456.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6Y9"/>
    <dbReference type="GeneID" id="24407812"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02447"/>
    <dbReference type="eggNOG" id="ENOG502RR5J">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052196_0_0_1"/>
    <dbReference type="OrthoDB" id="5416097at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13391">
        <property type="entry name" value="HNH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNH nuclease" evidence="2">
        <location>
            <begin position="184"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="284"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ26627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="484" mass="55156" checksum="4AF5251740FB7AB9" modified="2011-01-11" version="1">MNTNLPLPVSSDKVDRLCESLRNKLENADPYTRVTNRDIEMYERNFAERVPRNMDGRVDYLDDGQATLGCRREVMKEIHQIIQRDKDLQKMVCNDLFKKTLASARCWAVLLTMEWTNLVEFRDSLCAGDAKQKQRSLHGFLMACCNVGGLIWWMSETPTSTKEQIWLRSGAQREAAPRRDGFRCVLTHSAIIEECHMCPFWSLSRRTEIQRTVIAPLMDILGLEFSNRILGILEQTTPAGERTAPGDFDLLDSPANMITLSNQLHKLWDDGVFGLEPIRRLQQYKTVEKPDSQEKPGSGPSAVKRGAEASEHQPPHKKAAGKQTKSVDQEKLMYGIELRFHWLRKTTLGGLDDSPPTVDADPRELWKEWDADNVRDNAHATPLDNGHTVTIWSDDRRKIPNWDLVSIQWLAFRLHRLSGAANVDLYAPQKDQDDDEALAARVLQAKRDATEMVAERLGLNADELWADPRGPYYVPPENQGLDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q734</accession>
    <name>E3Q734_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_02492</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090692.1">
        <property type="nucleotide sequence ID" value="XM_008092501.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q734"/>
    <dbReference type="STRING" id="645133.E3Q734"/>
    <dbReference type="GeneID" id="24407857"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02492"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_13_3_1"/>
    <dbReference type="OrthoDB" id="498125at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (AFU_ORTHOLOGUE AFUA_6G11210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180:SF16">
        <property type="entry name" value="BACILYSIN BIOSYNTHESIS OXIDOREDUCTASE BACC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ26672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="347" mass="37029" checksum="E85F9C92237E9E37" modified="2011-01-11" version="1">MTIAQGYHNLVPVTKLSPPVDTTEPYDRSTLSGKTVLITGGALGLGAAFAREWASHGANVIVGDVNGSVGETLVAALRTDNPKGSHHFVTCDVTSWDSQVAFFKEGARLSPNGAIDVVVANAGVNDPGANYRFESPSALQTDPDAPGKPSNTIIDVNVTGLSYTAHLALFWLPRNGTSRDRCLIFVGSIAGVGHLPGQSPYTMSKHAVTGLFRSMRATAHLCHGIRLNMICPYFVSGSNMFQAPTEAAFLSGGAGAARLDDVVDATTRLVADEAIVGRALLVGPPIADGEGAEKVAVWDVYAEDYMDCEAFVWRWIRMVNTIEHVKGWAGLVGDVFSTLTKPLMWWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7D1</accession>
    <name>E3Q7D1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF8035 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_02589</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090789.1">
        <property type="nucleotide sequence ID" value="XM_008092598.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7D1"/>
    <dbReference type="STRING" id="645133.E3Q7D1"/>
    <dbReference type="GeneID" id="24407954"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02589"/>
    <dbReference type="eggNOG" id="ENOG502SANM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021705_2_0_1"/>
    <dbReference type="OrthoDB" id="5410752at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058348">
        <property type="entry name" value="DUF8035"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48148">
        <property type="entry name" value="KERATINOCYTE PROLINE-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48148:SF2">
        <property type="entry name" value="PA14 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26118">
        <property type="entry name" value="DUF8035"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF8035" evidence="2">
        <location>
            <begin position="413"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="357"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
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            <begin position="163"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
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            <begin position="202"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ26769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="518" mass="61774" checksum="41922D0D46266853" modified="2011-01-11" version="1">MAYRTNDFEERFYDDRRQRVDVRVKEREREREREGDRLRFLREERAPESGALVLSRREVESRELSRPRHRSPSPVYRERIVRKARSLTPPPRVHHDQELERSRVRISEREREIRSPSRGPPQEIRARYVERQRSPSPPPPARERSRVGVRIVEREREKERVPSPSPSPPPPPPQPQVIRGPTIEREVITHYRDIDHGVTRVPSPPPPPRPAPRPKVRTEDRELDIDITTSRRGTDIDIHRSHSRHRSPSRERRSPAFQDREIVLSTDRLRIDDHYHSGSRRRAHSAAARTPIDEESEYITSKIDSRGKMGEAWNGATKDWAIIDVPPGTERVRMDGVGGGSAEVTWQRYNGVRRAKFIPERDGAPSSVPAPEPSPRDSRDRLSLQLYDRETEIEIEKTKDRVPARRQPSKRNEMWTEITKDLVTRDAIIELGYDFEETEYFFYIMQYLKYDDVLELVQVSDEIRRFRKERVREYEREWVHDDWDRRSHHHHRHAPSKYDDERVYEREVVYDSQRPRRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7K9</accession>
    <name>E3Q7K9_COLGM</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02667</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000008782">
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    </dbReference>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="157" mass="17867" checksum="1F08FA4CB3C13E72" modified="2011-01-11" version="1">MIARWTHFFLPQRHFAQHGRIMVSITFTFSFGTCSLFIWHHFGCSLQDIRALGITTMIPGVRQKIDYHSHVTPLHDIFFLLFGLDFVSAFGLLGRHHTPLSWLGWWILGCNVGMVIPRSMCCHFTEPAGCGGKIVCLLGRAREASRLPANRIMQDIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q803</accession>
    <name>E3Q803_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_02186</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008092844.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q803"/>
    <dbReference type="GeneID" id="24407551"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02186"/>
    <dbReference type="eggNOG" id="ENOG502RQNQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1525026_0_0_1"/>
    <dbReference type="OrthoDB" id="5209965at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ27015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="176" mass="19446" checksum="BD2A67E72A3B719C" modified="2011-01-11" version="1">MKTTAAVPQITDTAARANQASRLSDCVPKQADLGIVDTHGDYENPRCNAIHADHHPGPYNVTCIMEQQAPAENIGDSDQLLPHRSSADPVQDRIDKMYHHAEDLKRSQHIMEHLAAGFIPMKGATHVPRDNVSKATMASTRSMENMLSQVSSTGLNREKLVSLDMAMTEDRKYTRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q832</accession>
    <name>E3Q832_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GH16 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_02215</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091064.1">
        <property type="nucleotide sequence ID" value="XM_008092873.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q832"/>
    <dbReference type="STRING" id="645133.E3Q832"/>
    <dbReference type="GeneID" id="24407580"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02215"/>
    <dbReference type="eggNOG" id="ENOG502S0II">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039765_0_1_1"/>
    <dbReference type="OrthoDB" id="4388755at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00413">
        <property type="entry name" value="Glyco_hydrolase_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38121">
        <property type="entry name" value="GH16 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38121:SF4">
        <property type="entry name" value="GH16 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180205" description="GH16 domain-containing protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="3">
        <location>
            <begin position="66"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ27044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="395" mass="43706" checksum="B49F1FE3608B80FC" modified="2011-01-11" version="1">MSFKRSPLLSLALALAPLVVADDRPYVADSVCNCYLTNSSERYFTNHVFFDFRNLGQYAGVPDALADWGASANAPVTSDYFNSDAWTSVWSIQSWNNTEVKGKNGNDATVDMVNSANNIYIERNSDRDASSDTFMSMRTVRTQGFQSSAEIESISMGYHFASVRMLARTIGAPGACTALFTYREADAYANVQEADIEVLTKDPENRIQYTNQPSFTAQGDTIDKSTQNGTMPRGTSWRDWAVHRIDWDEKDSTWLVDGSKVSKIAFQVPRDPSRIMLNSWSDGGSWSGIMNVNESAVMQIQWIDMVFNTTEESSSSSKRDVGLHRHGHGPVGRLERRDGDGKCQVVCSIDSSDTIGQPVMLHNGTAPGQLLGQSSAMAFWLPVALMSATFFHLWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q880</accession>
    <name>E3Q880_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7729 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_02263</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091112.1">
        <property type="nucleotide sequence ID" value="XM_008092921.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q880"/>
    <dbReference type="GeneID" id="24407628"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02263"/>
    <dbReference type="eggNOG" id="ENOG502S3AD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042319_0_0_1"/>
    <dbReference type="OrthoDB" id="2564812at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056146">
        <property type="entry name" value="DUF7729"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39460:SF1">
        <property type="entry name" value="C6 TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39460">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24855">
        <property type="entry name" value="DUF7729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180295" description="DUF7729 domain-containing protein" evidence="1">
        <location>
            <begin position="35"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7729" evidence="2">
        <location>
            <begin position="122"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ27092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="362" mass="38954" checksum="5F0EEE37AEF71CE8" modified="2011-01-11" version="1">MMAPASFTMPSLSIRPPRSLWLFLSLAIASTALASTPSSDALPALITAPAAMPPMDSLVVDDRTPIMVKGRWTMVPHEYAELKKRDESITPSPTTAGTATLQPTTLTVSVTVPAATVDLSSPLPSPFDTSLTFNFTSNDGASCPRFINSLLTNQNFKKCYPLSILLQGSESFFQAEKQLLSIVRVLDAACSADVEYCTGFLNGVAGNLTLDSNCGSDYQSGNPIVMQAYLGLKSYEMLYKATCLTDPDTSMYCFANAVTNLTTPANVYFYYLPLNMTLPASANPTCGSCLQRTMDIFQTYTMNRKLPIASTYEDAAAQVNTMCGPEYVNDTLLAAVSMAVLSAPSWTLTATMLALATAYNFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8F6</accession>
    <name>E3Q8F6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_02339</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091188.1">
        <property type="nucleotide sequence ID" value="XM_008092997.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3Q8F6"/>
    <dbReference type="GeneID" id="24407704"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02339"/>
    <dbReference type="eggNOG" id="KOG0732">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000536_1_0_1"/>
    <dbReference type="OrthoDB" id="5421at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006337">
        <property type="term" value="P:nucleosome disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045815">
        <property type="term" value="P:transcription initiation-coupled chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05491">
        <property type="entry name" value="Bromo_TBP7_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001218">
        <property type="entry name" value="AAA family ATPase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000061">
        <property type="entry name" value="ATPase family, AAA domain-containing 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045199">
        <property type="entry name" value="ATAD2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23069">
        <property type="entry name" value="AAA DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23069:SF0">
        <property type="entry name" value="TAT-BINDING HOMOLOG 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="9">
        <location>
            <begin position="623"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="454"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="509"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1299"/>
            <end position="1319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1333"/>
            <end position="1509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="62"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="112"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="147"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="201"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="267"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="299"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="316"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="346"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="374"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="392"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="405"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1301"/>
            <end position="1314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1343"/>
            <end position="1357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1392"/>
            <end position="1403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1431"/>
            <end position="1472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1493"/>
            <end position="1502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ27168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1614" mass="177437" checksum="29D503124D087030" modified="2011-01-11" version="1">MPTKRKRDIEDFDPNKSDSDDENFEPGADAPPTRTKKRSRGPRNQRSSGGRRRNNRYRGSDIEDDDEDDVSDSQDEGSFVSEEEEEVEDAPVNAAGRRARKAATKHNSYKESDDDESDIAEESDDVLSENMQKPKKKDSLMIKLKVPKSASKSAPAATITRRSTRARTEELGEELVELTNSGRRSRPASRSRSPEALARTRSSRSIKGLKKGPETIEEATQESSGPREDDVDIDELAANVQVAASEVKDTEMEDVKESTEQVKDDGVAADDDDDEDEGPITRRTRAKRGSHSAAGTAEPDVDADAEGEAEDDGPKRRLTRRNGLRKSKSVQEPSSDFEPGEESAEEEAHMSESPKKDSGDGDDGDFDSPAPRGRAAKPKGRSTRSSRRGAESAEEVELDQDELAEELHELRQDSRSRRTRRPSPAIIYQETVSKRRRAAAKPMNYFMPPLSAVNIEEDDAEDPAPTPARRRGGRGGATQAWDRALNTTFGPFGGGGGAGSLLTGPWGAGAAGGVDSDSSDDEMGQRSGAAGNVGMTPTSAAAPAGLLPGLAQPLGGDAGVGATPNVGKIKNQKALADADPLGVDLTVDFNHVGGLQGHIDQLKEMVQLPLLYPELFQKFHVTPPRGVLFHGPPGTGKTLLARALANSVGIGGRKITFYMRKGADALSKWVGEAEKQLRLLFEEARRTQPSIIFFDEIDGLAPVRSSKQEQIHASIVSTLLALMDGMDGRGQVIVIGATNRPDNIDPALRRPGRFDREFYFPLPDVAGRKSILEIHTKDWGLSEPFKQQLAENTKGYGGADLRALCTEAALNAIQRTYPQVYSSKDKLIVNPDNISIHATDFMLSIKKMVPSSERSAGTGAAPLPKGIGPLLRDQFGSIKKALNEVLPRKKKLTALEEAMFEQFEDEDQGFGREALHQEFERSRIFRPRLLIHGFSGMGQSYLSSALLHYFEGVQVQNFGLPNLLGDGRPMEQVIVSLFTEVKRHKPSVIYIPGIDSWYAAMRDTLPFITFKAMLKSIPPTDPILVLATAEYEAGEDLAPELVRELFAFSRKNRLQIERPKHSNRREYFSAIVEHVRKSPADFPDPANRKMRVLDQLPVAPPPPPRVPTKEEVKAMQKRDHQLLNILKVQLQPIMDQINRKYKKFRQPVITPGQLEYLFLEKDPNYVRPDVMGAEHRPFEIVKDKHGDDVLRETATGKTFYNLETTTIEERLSNGFYCRPKDFLKDIKSLAKDSKNIGDKERTLKANELVSNVEVDVATIEGNTSTVDWEALHQRQLQRAKAAAEKERKRKALQSVVDRVQTDITGGNDSDSQGPVTLGERIPGSAHALARFQVMSPGPGGASEAQQQSNGVSNPSRQSDVHMSGTDDDTTQDSSMQPPSQWPPQANPSTGITQVSQRSVVTTVPPGMSPSAIVNDASTTKTSDPSERSTDKWSTQATNGFHPDQFSQGDNSQLQDTQIPTGMGQVSQATSSDDAWPHSQAHGMARGVIRPPGSQTSSPSKSRSSGDSKHAMPLVNILNESTNDDIRNSGSSSSQQQPVIHEGQVEQFLDELTERTSGCTIEQLEQINRELMDEIWNTRHEWNRMKVLSDLTNVFNETISDIESIQGLFQQSQES</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q997</accession>
    <name>E3Q997_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_01771</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091296.1">
        <property type="nucleotide sequence ID" value="XM_008093105.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q997"/>
    <dbReference type="STRING" id="645133.E3Q997"/>
    <dbReference type="GeneID" id="24407136"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01771"/>
    <dbReference type="eggNOG" id="ENOG502S5DR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045556_0_0_1"/>
    <dbReference type="OrthoDB" id="5430750at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="266"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="322" mass="36924" checksum="55E50D09029D82A2" modified="2011-01-11" version="1">MLCRANGMATPTTRPDDIQREIVSSAEVFCREVQAIIDQTEELHKLVSSVSASTDPINAYNCRPHLPSSLVNAFEGILGLFVLKAKELSWMNRFAAKSGSSYSRNAERRLSRLKEACESTSRRVREHLVRAREDIIMLGTTKRDSERIIIAPIGPEFLAACLISSLQNNVPVPGTERRKLDLVAHYRNHTSRLWFNTSRKPTRGAFVAIHALEEELEALRVVVASQQHLLRSYQRLLSPLSFRSRSTDRLYYKDRKASFDLENKCIRRQQRRLAERDKALAILQRKARTLRDETKQRIEILDEGHGKAIRVFTIVTLFFLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9Y8</accession>
    <name>E3Q9Y8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Fatty acid hydroxylase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_02820</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091696.1">
        <property type="nucleotide sequence ID" value="XM_008093505.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9Y8"/>
    <dbReference type="STRING" id="645133.E3Q9Y8"/>
    <dbReference type="GeneID" id="24408185"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02820"/>
    <dbReference type="eggNOG" id="KOG0873">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047036_5_0_1"/>
    <dbReference type="OrthoDB" id="1658724at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050307">
        <property type="entry name" value="Sterol_Desaturase_Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11863">
        <property type="entry name" value="STEROL DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="5">
        <location>
            <begin position="148"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ27676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="307" mass="36349" checksum="BA6EA35FE220C9FD" modified="2011-01-11" version="1">MAAFINSTVINTAFNHTQPYFSVFEEVSKYNVQLNYFERLWAAWYLWMQNDILATGIMSFVMHETVYFGRSLPFIICDLIPWFHKYKIQPQKMPTLKEQWDCAMVVLISHFTVELPQIWLFHPLATWCGMEYGVPFPPLWKMAMQISIFFVMEDTWHYWFHRALHYGPLYKAIHKLHHYYSAPFGLAAEYASPIEVMLLGIGIVGSPIFWVTLTGDLHLLTMYAWIVLRLFQAIDAHSGYDFPWSLRHILPFWAGADHHDLHHEKFIGNYSSSFRWWDYCLDTEAGVEAHRKRREKKLKAIKAQKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QA58</accession>
    <name>E3QA58_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GH18 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_02890</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091766.1">
        <property type="nucleotide sequence ID" value="XM_008093575.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QA58"/>
    <dbReference type="STRING" id="645133.E3QA58"/>
    <dbReference type="GeneID" id="24408255"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02890"/>
    <dbReference type="eggNOG" id="KOG2806">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2026551_0_0_1"/>
    <dbReference type="OrthoDB" id="73875at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053214">
        <property type="entry name" value="LysM12-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47700:SF2">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47700">
        <property type="entry name" value="V CHITINASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G13720)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="GH18" evidence="4">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ27746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="122" mass="13519" checksum="361B336F7CE95991" modified="2011-01-11" version="1">MSYDLHGTWDAASKFVGPYVATHTNITEIDLGLDLLWRAGVKPKNVVLGQGFYGRSFTLEDSKCNKPNGVCRFSGGAKEGPCSKASGILNLQEIIDIIKDKKLEPVHDEKSGTKWIHWDNDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QA61</accession>
    <name>E3QA61_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">LysM domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_02893</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the secreted LysM effector family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091769.1">
        <property type="nucleotide sequence ID" value="XM_008093578.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QA61"/>
    <dbReference type="STRING" id="645133.E3QA61"/>
    <dbReference type="GeneID" id="24408258"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02893"/>
    <dbReference type="eggNOG" id="ENOG502SNDA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010591_5_1_1"/>
    <dbReference type="OrthoDB" id="1193027at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052210">
        <property type="entry name" value="LysM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997">
        <property type="entry name" value="AM15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997:SF2">
        <property type="entry name" value="LYSM DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="400"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="105"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="257"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="365"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="105"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="365"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ27749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="540" mass="57285" checksum="4EE899692E65B86F" modified="2011-01-11" version="1">MVTPDCAANPADPFCTNPRNVSAENRRISSLYDNDLLCSECFLKLLYARVTSAFLPGVDYSDYLVGEFQDIQEVCQTTVGELATRVLPNYPHTTDGDVTPIRTEVTSTETDAPAPTTTSEPVPTKAPVPDTEEGCEAVGWQWVDVLVMEESTIAQTELEFCNEIAEIYGVATGDLMYTTNTPGCAVLDGWSCVSPSCQLLRVSESSTCASIAESASNATHIVNAVQIATWNPHILGACDHLVKDQYVCIDRPGGSWTGPPASEIPDDSDGPVRGGPGSTPTLPIIDNPDTPPEPAQEGISSVCKRYVFADKGASCWKVSNDGGITQKRLFELNPVLGTNGENCDTMLWLNYYYCVGTESLGSPTTTVARTTSPTISPTASPTSAPKPSPTQEGIVGNCNKWVQAVAGDYCSKLANDAGIDTALFYQWNTVLGSGGENCGTMIWPDYYYCIGVSSGSATTSSPPTTTSAGPAKPTATHAGIPANCSTFAEAPAQGASCWQLATDNGIEPSRLYQLNPSLGTNGENCSTMIWPGYFYCVSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAA0</accession>
    <name>E3QAA0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed RNA polymerases I, II, and III subunit RPABC1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_02932</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091808.1">
        <property type="nucleotide sequence ID" value="XM_008093617.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAA0"/>
    <dbReference type="STRING" id="645133.E3QAA0"/>
    <dbReference type="GeneID" id="24408297"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02932"/>
    <dbReference type="eggNOG" id="KOG3218">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058320_0_0_1"/>
    <dbReference type="OrthoDB" id="248779at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003968">
        <property type="term" value="F:RNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006363">
        <property type="term" value="P:termination of RNA polymerase I transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006386">
        <property type="term" value="P:termination of RNA polymerase III transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006362">
        <property type="term" value="P:transcription elongation by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006361">
        <property type="term" value="P:transcription initiation at RNA polymerase I promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006384">
        <property type="term" value="P:transcription initiation at RNA polymerase III promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1340.10:FF:000002">
        <property type="entry name" value="DNA-directed RNA polymerases I, II, and III subunit RPABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.940.20:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerases I, II, and III subunit RPABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1340.10">
        <property type="entry name" value="RNA polymerase, Rpb5, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.940.20">
        <property type="entry name" value="RPB5-like RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00025">
        <property type="entry name" value="RNApol_Rpo5_RPB5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014381">
        <property type="entry name" value="Arch_Rpo5/euc_Rpb5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005571">
        <property type="entry name" value="RNA_pol_Rpb5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036710">
        <property type="entry name" value="RNA_pol_Rpb5_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000783">
        <property type="entry name" value="RNA_pol_subH/Rpb5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020608">
        <property type="entry name" value="RNA_pol_subH/Rpb5_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035913">
        <property type="entry name" value="RPB5-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007129">
        <property type="entry name" value="PRK09570.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10535">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10535:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01191">
        <property type="entry name" value="RNA_pol_Rpb5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03871">
        <property type="entry name" value="RNA_pol_Rpb5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000747">
        <property type="entry name" value="RPB5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53036">
        <property type="entry name" value="Eukaryotic RPB5 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55287">
        <property type="entry name" value="RPB5-like RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01110">
        <property type="entry name" value="RNA_POL_H_23KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RNA polymerase Rpb5 N-terminal" evidence="7">
        <location>
            <begin position="9"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase subunit H/Rpb5 C-terminal" evidence="6">
        <location>
            <begin position="157"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ27788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="230" mass="26376" checksum="616281CDC3334FCD" modified="2011-01-11" version="1">MSDQKDVNKEVTRLWRAWRTAHEMAADRGYELAEDELTISLDRFKMEYTSADGSVNRNKLQFSANPSAEMIRKFTPPATPQNPNPAPECGTLWVEFLADTTFGIKEIKKFIHHLISNKYSSGIMITHVALSPAARKMLITIESFAKVECFLEEDLLVNITKHELVPKHILLSREEKIALLKRYRLKETQLPRILQKDPVAKYLGLKRGQVVKIIRTSETAGRYASYRLCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBX7</accession>
    <name>E3QBX7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">SPX domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_03356</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092232.1">
        <property type="nucleotide sequence ID" value="XM_008094041.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBX7"/>
    <dbReference type="STRING" id="645133.E3QBX7"/>
    <dbReference type="GeneID" id="24408721"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03356"/>
    <dbReference type="eggNOG" id="KOG1162">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048481_0_0_1"/>
    <dbReference type="OrthoDB" id="5588846at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006799">
        <property type="term" value="P:polyphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14474">
        <property type="entry name" value="SPX_YDR089W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051572">
        <property type="entry name" value="VTC_Complex_Subunit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140:SF1">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE COMPLEX SUBUNIT 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="364"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="400"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="434"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="SPX" evidence="8">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="199"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ28212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="458" mass="51640" checksum="9262742976BAD2AD" modified="2011-01-11" version="1">MKYGQQLEQESVPEWSLHNVDYNSLKHEIKVHTTRDQATAIAIPGHQDSALKRFEDNLYNELCQQHDRVDLFVSSKADEISRRLQYISDQLQKLIVKCAEDGDHVTLKRHRRFAKYERDLLRCGEETLALARFINAQITAFRKITKKYKKWTGSPTLGARFREGVLADPKSFTRRDLNNLQTRYEELLNALRTSIPQLSEPSSPFSDELVPTRPGSGADEFFSPLPPARRQPRPVAQQYEQQQQHYWNEYDDGSEAGGQDDEYAIYINPDDDVSFPGLDSMRAILAAPFRHARRWFSRRQDPAGQRLLGNAPFLESYGGISALGTDTDDEYASSDGMPTTGYATHYATLPSVGEQHVRRYREQVLFWGTIGCFGFSFLLLLVAGILISTGRHKLRAEVDAGVTVGVVASLFSACLALGMSLYRRDDLGVWQRVAVYSSFFAACALNGMLLILVVGNAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBZ9</accession>
    <name>E3QBZ9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_03378</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092254.1">
        <property type="nucleotide sequence ID" value="XM_008094063.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBZ9"/>
    <dbReference type="STRING" id="645133.E3QBZ9"/>
    <dbReference type="GeneID" id="24408743"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03378"/>
    <dbReference type="eggNOG" id="ENOG502RNYD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104699_0_0_1"/>
    <dbReference type="OrthoDB" id="5431013at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ28234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="166" mass="18118" checksum="8902628489A0B467" modified="2011-01-11" version="1">MASSPDMAGIANLGSQLATKLVAYEIGTSRSDYSIHRLVEDIFATTTALGELREFLAADASAALPVYKRAGREAIEDLATRCGKVYTTIIRIIYRASLAAKVVEGVDFEALSPQDLKPSRLIAIQANIKWGSVSDAFDDCRDQLRWLKPSLLLHLQVANIAHLQTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QC46</accession>
    <name>E3QC46_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">xylan 1,4-beta-xylosidase</fullName>
            <ecNumber evidence="13">3.2.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">GLRG_03578</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>Hydrolysis of (1-&gt;4)-beta-D-xylans, to remove successive D-xylose residues from the non-reducing termini.</text>
            <dbReference type="EC" id="3.2.1.37"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycan degradation; xylan degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.37" evidence="13"/>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092454.1">
        <property type="nucleotide sequence ID" value="XM_008094263.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QC46"/>
    <dbReference type="STRING" id="645133.E3QC46"/>
    <dbReference type="GeneID" id="24408943"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03578"/>
    <dbReference type="eggNOG" id="ENOG502QQ55">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004542_5_3_1"/>
    <dbReference type="OrthoDB" id="47059at2759"/>
    <dbReference type="UniPathway" id="UPA00114"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046556">
        <property type="term" value="F:alpha-L-arabinofuranosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009044">
        <property type="term" value="F:xylan 1,4-beta-xylosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031222">
        <property type="term" value="P:arabinan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1700:FF:000007">
        <property type="entry name" value="Exo-1,4-beta-xylosidase xlnD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044993">
        <property type="entry name" value="BXL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42721:SF3">
        <property type="entry name" value="BETA-D-XYLOSIDASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42721">
        <property type="entry name" value="SUGAR HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0858">Xylan degradation</keyword>
    <feature type="domain" description="Fibronectin type III-like" evidence="14">
        <location>
            <begin position="613"/>
            <end position="684"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00026107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EFQ28434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="728" mass="78980" checksum="C440D34588696DC6" modified="2011-01-11" version="1">MSVEEKVRNLVDASAGVKSLGLPPHGWWNEGLHGVGFSPGVLFAQDSEPFGYATSFPLPILTAASFDDDLFNAIGQVIGREGRAFSNYGYAGFNFWTPNMNAFRDPRWGRGQETPGEDVLVVSNYVQSYVTGLQGSDPTDKVIIAACKHFAAYDIETARRANNYNPTQQDLQDYYLPAFRRCVRDSHVGTVMCSYNSVDGIPACSSEYLLKEVLRDTWGFTNDYQFVVSDCGAVTDVWLLHNFTNTEQDAASVSMAAGTDLECGSSYLHLNGSLADKQVTQERVDEALTRLYKALFTVGYFDGSSHSSLGWSDVSTIDAQQIACEAARAGMTLLKNDGVLPLADGKYKSVALIGPFANATTQMQGNYFGRAPFVRSPLWAFTQQSSLQVNYAAGTDINSTSDSGFADALAAAKNSDIVIFCGGIDTTIEAETLDRVSITWPGNQLDLISQLSMLGKPLVVAQFGGGQVDDTALVDNANVNALFWAGLPGQAGGLAMYDLVVGKASFAGRLPTTQYPASYADLVSIFNINLRPNGTFPGRTYKWYIGEPVFPFGFGLHYTKFNFTWKDTLEPTYDISNIISWARSQNNGHVTDTTPFTSVNVTVKNVGNVRSDYVGLLFLSSKNAGPVPRPNKSLASYSRAHDIETGASDQLTLKLTLGSFARSDSQGNLTIFPGDYKLELDNDKSLVFDFTLTGDPAVIDSLPAPKPSYEFAVPVHIQPPSDRPLGPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCB4</accession>
    <name>E3QCB4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Ras family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_03646</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092522.1">
        <property type="nucleotide sequence ID" value="XM_008094331.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCB4"/>
    <dbReference type="STRING" id="645133.E3QCB4"/>
    <dbReference type="GeneID" id="24409011"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03646"/>
    <dbReference type="eggNOG" id="KOG0393">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041217_21_3_1"/>
    <dbReference type="OrthoDB" id="8830751at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051286">
        <property type="term" value="C:cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030427">
        <property type="term" value="C:site of polarized growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030010">
        <property type="term" value="P:establishment of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01874">
        <property type="entry name" value="Cdc42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000236">
        <property type="entry name" value="Cell division control protein 42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037874">
        <property type="entry name" value="Cdc42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0636">Prenylation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ28502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="219" mass="24677" checksum="EAF7F8ABEBC86DDB" modified="2011-01-11" version="1">MVVATIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGDEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVTSPASFENVREKWFPEVHHHCPGVPCLIVGTQVDLREDPSVREKLSKQKMSPVRKEDGERMAKDLGAVKYVECSALTQYKLKDVFDEVWISELHLVPDFPLRWKPNIDMRPQAIVAALEPPAPKKKSHKCLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCP5</accession>
    <name>E3QCP5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_03777</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092653.1">
        <property type="nucleotide sequence ID" value="XM_008094462.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCP5"/>
    <dbReference type="GeneID" id="24409142"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03777"/>
    <dbReference type="HOGENOM" id="CLU_2621894_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ28633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="78" mass="9241" checksum="2BFA1C8BE50C564E" modified="2011-01-11" version="1">MVPKPLKRGANTWPHLAEPPKEEGEEEREEEEEEEEEEEEEEEEEEEEEEEEEREGAWNSKTQLFHGLLSTLMLSISN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCQ4</accession>
    <name>E3QCQ4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transporter particle component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_03786</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAPP small subunits family. BET3 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092662.1">
        <property type="nucleotide sequence ID" value="XM_008094471.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCQ4"/>
    <dbReference type="STRING" id="645133.E3QCQ4"/>
    <dbReference type="GeneID" id="24409151"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03786"/>
    <dbReference type="eggNOG" id="KOG3316">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076409_0_1_1"/>
    <dbReference type="OrthoDB" id="941624at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005801">
        <property type="term" value="C:cis-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030008">
        <property type="term" value="C:TRAPP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14944">
        <property type="entry name" value="TRAPPC6A_Trs33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.20">
        <property type="entry name" value="Trafficking protein particle complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024096">
        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007194">
        <property type="entry name" value="TRAPP_component"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037992">
        <property type="entry name" value="TRAPPC6/Trs33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12817:SF0">
        <property type="entry name" value="GEO08327P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12817">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04051">
        <property type="entry name" value="TRAPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111126">
        <property type="entry name" value="Ligand-binding domain in the NO signalling and Golgi transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="46"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ28642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="244" mass="26094" checksum="1F29BB8373FE0539" modified="2011-01-11" version="1">MSFESVMPPYNATDPSASFLNSSCLDFLLIELVPLAFRVTRELDDDLPSGDAANRTGADAPSSAGGRASADALSSVSHTHGGGAAGGPAPSSAEGAAGGSMARKMDEDEERDAVFYRLETLGYRVGQGLVERFSRDRPRFNDTLDVIKFVCKDLWSLVFRKQVDNLKTNHRGVYVLTDNSFKPFSRMSTEAGGQAVVRAQPFLWFPCGIVRGALAALGINATVQAETNELPAAIFQIKTLPSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDM1</accession>
    <name>E3QDM1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Endo-1,4-beta-xylanase C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_04103</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 10 (cellulase F) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ28959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092979.1">
        <property type="nucleotide sequence ID" value="XM_008094788.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDM1"/>
    <dbReference type="STRING" id="645133.E3QDM1"/>
    <dbReference type="GeneID" id="24409468"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04103"/>
    <dbReference type="HOGENOM" id="CLU_2978983_0_0_1"/>
    <dbReference type="OrthoDB" id="3055998at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031176">
        <property type="term" value="F:endo-1,4-beta-xylanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001000">
        <property type="entry name" value="GH10_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00331">
        <property type="entry name" value="Glyco_hydro_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51760">
        <property type="entry name" value="GH10_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0858">Xylan degradation</keyword>
    <feature type="domain" description="GH10" evidence="5">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ28959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="58" mass="6708" checksum="60E5F9591EFF6059" modified="2011-01-11" version="1">MMWQEVVNEIFNDNGTLRNNTFFNVMGESYVGVAFRAARVADPTAKLYIDDYNLDNKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDW2</accession>
    <name>E3QDW2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04194</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093070.1">
        <property type="nucleotide sequence ID" value="XM_008094879.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDW2"/>
    <dbReference type="STRING" id="645133.E3QDW2"/>
    <dbReference type="GeneID" id="24409559"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04194"/>
    <dbReference type="eggNOG" id="ENOG502SFZ8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_157438_2_0_1"/>
    <dbReference type="OrthoDB" id="5239630at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019034">
        <property type="entry name" value="UPF0390"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09495">
        <property type="entry name" value="DUF2462"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="93" mass="9742" checksum="DCF6BAC3A50CFAF0" modified="2011-01-11" version="1">MAQGGIKSSSRPAPTGKPKQKSTKNASRVAKPQKAKAHGSADKLQKKLAAGLVSRTEKLLGERAGHLELIGKGKKAKGAKDEKTHKGGSRKYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEG7</accession>
    <name>E3QEG7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04417</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093293.1">
        <property type="nucleotide sequence ID" value="XM_008095102.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEG7"/>
    <dbReference type="GeneID" id="24409782"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04417"/>
    <dbReference type="HOGENOM" id="CLU_2003750_0_0_1"/>
    <dbReference type="OrthoDB" id="10411468at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="124" mass="13832" checksum="4546DD3B5AA58A4B" modified="2011-01-11" version="1">MHGMAWYRHSRDFWGFMGPQTGVLGATRRNLTSERAVQVHSLIRKTEKEGTGRTYPRHHDEVRPPVAEVRQVGDERRLPSAGDRTSPAGIAESGLQRQDGDGDTTDPRSPLIWTSPIISNLVCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFA2</accession>
    <name>E3QFA2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Eukaryotic aspartyl protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_04684</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093560.1">
        <property type="nucleotide sequence ID" value="XM_008095369.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFA2"/>
    <dbReference type="STRING" id="645133.E3QFA2"/>
    <dbReference type="MEROPS" id="A01.082"/>
    <dbReference type="GeneID" id="24410049"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04684"/>
    <dbReference type="eggNOG" id="KOG1339">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013253_9_4_1"/>
    <dbReference type="OrthoDB" id="771136at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05474">
        <property type="entry name" value="SAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033876">
        <property type="entry name" value="SAP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF65">
        <property type="entry name" value="ASPARTIC-TYPE ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178420" evidence="7">
        <location>
            <begin position="18"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="8">
        <location>
            <begin position="68"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ29540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="458" mass="48793" checksum="4D3797FDAFEAAA52" modified="2011-01-11" version="1">MATRWLPLTALAVGVSAVSVRREQTDSTPGVISLPVYQDIRIHPLEKLRRREVEDTDAPVYNVTSTTYLIELSIGTPGQDTKVAIDTGSSELWVNPTCANAGTTAMVQSCRANGQYDPRDSSTSVVYVDQGNITYGKGTVELQYVSDNITIPGSDISLSDTIFGYGIYSADLSRGILGLSFGEATNTTDYPTVLDTMKAQNVIESLTVGIALGTKEEKTGSGLISFGGVDTKKFSGNLHSAPVLGPQNGEDLRRYWVQLDSVGLSKSGRSTKTYANTQFPVFFDTGATLSYFPPALVDQLGSDLGGRLESSINMYLVPCNTKGTINFKFGDYTMKVPLSEFIWQVGDNSCVLGADKASDNAYILGDSFLRSAYVVFDQETPALHFAPYVNCGSNLQKIPLGSNAAAKFTGECQASSNDGSGSGSGGSDNENVAGRATPVGIWMVAGALLAVQVFMSFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFB7</accession>
    <name>E3QFB7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Urea transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_04699</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093575.1">
        <property type="nucleotide sequence ID" value="XM_008095384.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFB7"/>
    <dbReference type="STRING" id="645133.E3QFB7"/>
    <dbReference type="GeneID" id="24410064"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04699"/>
    <dbReference type="eggNOG" id="ENOG502QU2F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023225_0_0_1"/>
    <dbReference type="OrthoDB" id="6132759at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015606">
        <property type="term" value="F:spermidine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="entry name" value="Sodium/glucose cotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050277">
        <property type="entry name" value="Sodium:Solute_Symporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48086:SF10">
        <property type="entry name" value="AGR155CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48086">
        <property type="entry name" value="SODIUM/PROLINE SYMPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="182"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="272"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="298"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="331"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="372"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ29555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="454" mass="49021" checksum="2C4DAD4C910017E3" modified="2011-01-11" version="1">MVYSLSSSLPLLVFAFLGPIIRRKTPEGFVLTAWTRQRYGTVAMLYLSFMTLVTLFLYMVAELSAIGQVVNALTSLDGLPVMIVQCVVTTIYTSLGGFRISFVTDNLQGAMVVCLIVIVGIAMGVKTDIDTSLIESSGLLKPTLLGWQLLYILPVCILTNDFFLSGFWLRTFASKTDRDLRVGVSIAVAVILCILTLVGVTGLVAAWSGALPLDQVAENGSVAFFLLLERMPAWVVGLVLVMVCTLSTAAFDSLQSAMVSSASNDLFRNRLNIWWIRAAVVLVIAPTIVIALKAPSVLQIYLISDLVSASVIPVLVLGLSDRFYWWRGFEVVAGGLGGILTVFLFGLVYYDGDASRAGNLLILSEGLYADDWSAFGAFVAAPVGSFLWGFAALGCRLAFQYVAARRSGRRFDALDDPAVAPDAASADGAPRFVERDEYEATSDVEVVKPAGKFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFC7</accession>
    <name>E3QFC7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transmembrane protein 14C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_04709</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM14 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093585.1">
        <property type="nucleotide sequence ID" value="XM_008095394.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFC7"/>
    <dbReference type="GeneID" id="24410074"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04709"/>
    <dbReference type="eggNOG" id="KOG4267">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096652_3_1_1"/>
    <dbReference type="OrthoDB" id="5620at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1740">
        <property type="entry name" value="Transmembrane protein 14-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005349">
        <property type="entry name" value="TMEM14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044890">
        <property type="entry name" value="TMEM14_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12668:SF53">
        <property type="entry name" value="TMEM14 PROTEIN HOMOLOG YJR085C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12668">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 14, 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03647">
        <property type="entry name" value="Tmemb_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ29565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="108" mass="11342" checksum="FBCDBBE86E95471E" modified="2011-01-11" version="1">MAEHPAFTLAGLLAGGGTFGFYRTRSKPSLIAGLTLGASFACAGYLLKKNKDYGAELALGSSVLLLGAGAQRMIATQAKSRPAIGLSVAGALSTFYYQKKFREFRFGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFU9</accession>
    <name>E3QFU9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD superfamily phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_04928</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093804.1">
        <property type="nucleotide sequence ID" value="XM_008095613.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFU9"/>
    <dbReference type="STRING" id="645133.E3QFU9"/>
    <dbReference type="GeneID" id="24410293"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04928"/>
    <dbReference type="eggNOG" id="KOG2961">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056221_3_2_1"/>
    <dbReference type="OrthoDB" id="198652at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031314">
        <property type="term" value="C:extrinsic component of mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008962">
        <property type="term" value="F:phosphatidylglycerophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032049">
        <property type="term" value="P:cardiolipin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000165">
        <property type="entry name" value="HAD superfamily phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027706">
        <property type="entry name" value="PGP_Pase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010021">
        <property type="entry name" value="PGPP1/Gep4"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01668">
        <property type="entry name" value="YqeG_hyp_ppase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09419">
        <property type="entry name" value="PGP_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ29784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="199" mass="22335" checksum="89FFB880B9B9FFD3" modified="2011-01-11" version="1">MNLNLSGTVNIFKLFSRPALCLPQHTVATFNDLPIPLHKAFEGQDRKCDIRAVVLDKDDCFAIPHTNEVHKPYKERFEKLKATYPGRRLVIVSNTAGATSYDTSLKLAKELEEETGITVLPHKTKKPGCGSEIMEYFRNHPETGVSHPSQVAVVGDRLTTDMMLANMMGGWGFWIRDGVVPPEKKSIVSGLIFNWKAFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QG17</accession>
    <name>E3QG17_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">RWD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_04996</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IMPACT family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093872.1">
        <property type="nucleotide sequence ID" value="XM_008095681.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QG17"/>
    <dbReference type="STRING" id="645133.E3QG17"/>
    <dbReference type="GeneID" id="24410361"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04996"/>
    <dbReference type="eggNOG" id="KOG3299">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045276_0_1_1"/>
    <dbReference type="OrthoDB" id="69641at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140469">
        <property type="term" value="P:GCN2-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006446">
        <property type="term" value="P:regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23822">
        <property type="entry name" value="RWD_ScYIH1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.30">
        <property type="entry name" value="Impact, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023582">
        <property type="entry name" value="Impact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001498">
        <property type="entry name" value="Impact_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036956">
        <property type="entry name" value="Impact_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020569">
        <property type="entry name" value="UPF0029_Impact_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301">
        <property type="entry name" value="IMPACT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301:SF25">
        <property type="entry name" value="PROTEIN IMPACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01205">
        <property type="entry name" value="Impact_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00910">
        <property type="entry name" value="UPF0029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0678">Repressor</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <keyword evidence="5" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="RWD" evidence="8">
        <location>
            <begin position="7"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="106"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="119"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ29852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="276" mass="29694" checksum="56974C66DECB5390" modified="2011-01-11" version="1">MSDDLRDEIEALNSIYGDDTLRPSPPNYILALPGGPGATSLTLRFPDSYPDVPPEVLGTHSAGENAPRGAGARDLAVFRDAVANVYQPGAVCLFDAVEEFSRLLEEHAGAEPSPPPPPPEKDEGKEEHGTRPAPLAEEPPWVVSDPFVELKSVFLARAAPVASPAQAAGYVQHLLATDKKVRAATHNMTAWRVRGPNGTSFQDCDDDGETAAGSRLLHLMQLMDLWDVMVVVSRWYGGQKLGPRRFALINSAARDAFVKAGWVEEAGQGKKKGHGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QG56</accession>
    <name>E3QG56_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05035</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093911.1">
        <property type="nucleotide sequence ID" value="XM_008095720.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QG56"/>
    <dbReference type="STRING" id="645133.E3QG56"/>
    <dbReference type="GeneID" id="24410400"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05035"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_44_4_1"/>
    <dbReference type="OrthoDB" id="542013at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="322" mass="35663" checksum="FCE4381903141F80" modified="2011-01-11" version="1">MNPVDFFRSQFKKLPYPTEDCAGRTVIVTGSNVGLGLEAARHFVRLNAAKVILAVRSTEKGEAAKANIELTTGRHGVLEVWPLDQLSFDSVKDFAARADQLPRLDYLLLNASIATNERIEAEGWESSLTVNVLSTFLLGFKLLPVMRRTGKTHNVTPKIVITASEASQLAKFRERNAENIYKALNANKSLLDRYNTTKLMQVILGRQMAIAADASDKGRVQVTTLNPGLCSTELFRHLPFPLTIILNVILKLVARSPEVGSRCLMASAFAGEEAHGRYMSDCAVVEFPKIMQGEEGEQMQKRLWEETVEILDDVDSGVSKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHF8</accession>
    <name>E3QHF8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_05464</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697348">
        <property type="protein sequence ID" value="EFQ30320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094340.1">
        <property type="nucleotide sequence ID" value="XM_008096149.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHF8"/>
    <dbReference type="GeneID" id="24410829"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05464"/>
    <dbReference type="eggNOG" id="ENOG502T6XB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_836814_0_0_1"/>
    <dbReference type="OrthoDB" id="4851858at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180525" evidence="2">
        <location>
            <begin position="19"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="133"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="177"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="221"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="260"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="296"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ30320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="391" mass="39725" checksum="766DF8BA72AF8F5C" modified="2011-01-11" version="1">MKSSILLSIAAIAAQVIALPTHDERSVALHARNMNLAANVDVRPSLRRNKAEAQADEEDDLKEEDVKEDAAAELDAPKDKAGEAAANTPAEAAAGDAAANNGTANAGDDEGKNKDDKNKDDKNKDDKNKDNEAAAGAANNGTANAGDDEGKNKDDKNKDDKNKDDKNKDDKNKDNEAAAGAANNGTANAGDDEGKNKDDKNKDDKNKDDKNKDDKNKDNEAAAGAANNGTANAGDDEGKNKDDKNKDDENKDDKNKDNEAAAGAAKNGTANAGDDKGKQNKDDNKDAKKNKDNGEDNGAAAGAANNGTANAVDGKGKKDNDAKAKENGDAGGAADAGKAAAGDNQILADILSGLTGGAGAGAGAAGGQKQSNPLALLSGLLGRDQESGDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHW2</accession>
    <name>E3QHW2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heterokaryon incompatibility protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_05594</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697349">
        <property type="protein sequence ID" value="EFQ30450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094470.1">
        <property type="nucleotide sequence ID" value="XM_008096279.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHW2"/>
    <dbReference type="STRING" id="645133.E3QHW2"/>
    <dbReference type="GeneID" id="24410959"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05594"/>
    <dbReference type="eggNOG" id="ENOG502R98Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004184_7_2_1"/>
    <dbReference type="OrthoDB" id="2157530at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF73">
        <property type="entry name" value="HET DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G01020)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26639">
        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="42"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ30450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="641" mass="70461" checksum="65FEE093B560DD0D" modified="2011-01-11" version="1">MHSIYQHLPQGYIRLLTLQPGDVSAELSCTLQSTPLESAPEYEAVSYAWGSEGFTDSLAVSSSPGPTTSQAVVSITPNVTCLLKSLRRATEPRVLWIDAICINQADISERGVQVQQMRSIYTRALRTVIWLGPATEDGSSDSALEFLKKMAIDKKNCDRGRWINGERVASDTSSETGSGRAALNGVYFDEHEDEDDGVENDADSFDNQSAQGASTTTGDDAELVVGSSRASLKAGAGGAELSNAFISAFAYLRDVVREWVDEIKWKASMNYRYYITLGYWNPLECRRRIQRWDRGMVAWEKNRSVSHIAFGIPVLYENSMYGFFEERYHSDWAAVDQLLGRPWWSRTLVDGKLSDLLWNTWDRDAQDPRDKVFALLGLVRKSEGLLKPDYGKSTRRVFCEAARDIIRTEESLDILLAAGGPRAQCDGGRLPSWVPDWRRKANDARPVLFVNRARLLTLYISGSMDQIVVNGHGYSACGDEKAVAWFGGDLATLHVHAVLIDEVGPVGTPQGPGPVEAGAVIDDAFSVASAAFAEKAASLSSLSWWWEGKQKNKLTDVVERALCAGSPGEKTKSEVIENVAPLRRFFMTKQKQLACLGPSSVQPGDKVFVIAGCNFPMVLREGVPGPNGEPGMFELVGEAYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIH6</accession>
    <name>E3QIH6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MATE efflux family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_05730</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094606.1">
        <property type="nucleotide sequence ID" value="XM_008096415.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIH6"/>
    <dbReference type="STRING" id="645133.E3QIH6"/>
    <dbReference type="GeneID" id="24411095"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05730"/>
    <dbReference type="eggNOG" id="KOG1347">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012893_1_2_1"/>
    <dbReference type="OrthoDB" id="2126698at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990961">
        <property type="term" value="P:xenobiotic detoxification by transmembrane export across the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13132">
        <property type="entry name" value="MATE_eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045069">
        <property type="entry name" value="MATE_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11206">
        <property type="entry name" value="MULTIDRUG RESISTANCE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="293"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="358"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="383"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="430"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="468"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="509"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="542"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="578"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="608"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="37"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="42"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ30586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="647" mass="71038" checksum="A49A496723F4C463" modified="2011-01-11" version="1">MGDDRSIPIKASSSHDFVTQLSSSFRVGTPRAQEILARDLAECSDEEPPDENDDDAIGSVSQSESEEGPLFYRRPSGVAFGTSRPVMNPQTHAVEEQPVLTRVEKKQSRDAERSLLRDNHILPPKNPRTDHEPFYRRAYRRLFSTKVPLEPHDEEAPQVVVCRPTESTPLLSGTAPASGADGHEHLNEQWDAAVAMDQLRTTWQRETKTIVQYASPLIVTFMLQYSINVVAIFAVGRIGKMELGAVSLASMTATITAYAPFQGLATSLDTLCAQAYGSGHRHLVGLQFQRMTYFMLMCFVPIAVLWFFAEAVLSLIIPEPESARLAGQYLRVMILGGPAFICFEGGKRFVQAQGLFQATTWVLLIAAPINIFLNWLFVWRLGWGFVGAPAAAVCTQNLLPLLLFLYVRFVNGYQCWGGFSKRAFTNLGPMLRLALPGMVMIEAEYMAFEVLTLLSSHFGPSYLAAQSVVFTLCAITYQIPFPVSIAASTRIANLIGAGLVDAAKTTGKVAFVAALIVGIFNVILFSSFRFHLPRLFTSDEEVIAIVADVLPLCAMMQVFDGLSAGAHGLLRGIGRPSIGGYATISVYYFIALPLSFGTAFGLGWKLKGLWLGVTIGLALVSLIEYSFVYFSDWHKAAKEADARNQAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIT5</accession>
    <name>E3QIT5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mitochondrial thiamine pyrophosphate carrier 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">GLRG_05917</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094793.1">
        <property type="nucleotide sequence ID" value="XM_008096602.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIT5"/>
    <dbReference type="STRING" id="645133.E3QIT5"/>
    <dbReference type="GeneID" id="24411282"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05917"/>
    <dbReference type="eggNOG" id="KOG0752">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_10_0_1"/>
    <dbReference type="OrthoDB" id="270584at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015228">
        <property type="term" value="F:coenzyme A transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24089">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="346"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="45"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="144"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="286"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EFQ30773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="377" mass="41308" checksum="A49F021B08BE65FB" modified="2011-01-11" version="1">MSEIAPNKQRDAVRLKPDMPPRAPPVRPTDDDETVATRKQTRTFDYIWRSGVAGGLAGCAAKTVVAPLDRVKILFQASNPQFAKYTGSWFGVVTAMKDIRSHEGLTGLFRGHSATLIRIFPYAGIKFLAYEQIRSLVIRRKDQETPWRRLISGSMAGVTSVFFTYPLEVIRVRLAFETKHGGSSLVNICRRIYNERFVRASAAAKAASTPATEATAASAVAAIAPRSGLINFYRGFTPTLLGMLPYAGMSFLTHDTAGDLLRHPSVAKWTTIAQPKDSPAGKAVPLRSWAELLAGGVAGLVSQTASYPLEVIRRRMQVGGAVGDGHRLRISETAAMIFRERGLPGFFVGLTIGYVKVVPMAAVAFYTYERAKMWLRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIV9</accession>
    <name>E3QIV9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Thioredoxin reductase</fullName>
            <ecNumber evidence="8">1.8.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_05941</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>[thioredoxin]-dithiol + NADP(+) = [thioredoxin]-disulfide + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20345"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="9">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.9" evidence="8"/>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094817.1">
        <property type="nucleotide sequence ID" value="XM_008096626.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIV9"/>
    <dbReference type="STRING" id="645133.E3QIV9"/>
    <dbReference type="GeneID" id="24411306"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05941"/>
    <dbReference type="eggNOG" id="KOG0404">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031864_5_1_1"/>
    <dbReference type="OrthoDB" id="371245at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004791">
        <property type="term" value="F:thioredoxin-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019430">
        <property type="term" value="P:removal of superoxide radicals"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000064">
        <property type="entry name" value="Thioredoxin reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050097">
        <property type="entry name" value="Ferredoxin-NADP_redctase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008255">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_2_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005982">
        <property type="entry name" value="Thioredox_Rdtase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01292">
        <property type="entry name" value="TRX_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48105">
        <property type="entry name" value="THIOREDOXIN REDUCTASE 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00469">
        <property type="entry name" value="PNDRDTASEII"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00573">
        <property type="entry name" value="PYRIDINE_REDOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 8" id="KW-0274">FAD</keyword>
    <keyword evidence="2 8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 9" id="KW-0521">NADP</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7 8" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="10">
        <location>
            <begin position="4"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ30797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="330" mass="35158" checksum="E9EEDA81332E5614" modified="2011-01-11" version="1">MHSKVVIIGSGPAAHTAAVYLARAELKPVLYEGFMANGIAAGGQLTTTTDVENFPGFPKGIMGGELMENMKAQSARFGTEIITDTVSKLDLSSRPFKYSTEFSPDETHTADAIILATGASAKRLNLPGEEKYWQNGVSACAVCDGAVPIFRNKHLVVIGGGDSAAEEALYLTKYGSHVTVLVRRDVLRASQIMAKRLLSNDKVTVRWNSVGKEIKGGADGLMSHLVVQDTVTGKEETLEANGLFYAIGHEPATTLVKGQLETDSEGYVVTKPGTPLTNIEGVFAAGDVQDKRYRQAITSAGTGCMAAMDAEKYLAELEDGDAKDPNNNPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIW5</accession>
    <name>E3QIW5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_05947</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094823.1">
        <property type="nucleotide sequence ID" value="XM_008096632.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIW5"/>
    <dbReference type="STRING" id="645133.E3QIW5"/>
    <dbReference type="GeneID" id="24411312"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05947"/>
    <dbReference type="eggNOG" id="ENOG502SKQE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028906_4_1_1"/>
    <dbReference type="OrthoDB" id="5412996at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF37">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ30803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="470" mass="53688" checksum="99180832DC2A4EE3" modified="2011-01-11" version="1">MVRVPWPSTVQFPGEKTLYEAATSEYLRLNTCVPVPQVLHYVRESDIGPMLIIRRVEHGCDMTDLLAIPGRDPGLPPALNLSLPESKLRSLWGKMSWILMELERPKFPRIGSLLEVNGSFQVAGRPLTQNLNSLTQLAHVPPTIFPVKDKTFTTAGEWYLELSNMNLAQLLFQHNNLVASEDDCRNKYVARHLFRRLAKQSRLSTFGFLQDNLSTPGSKKMTRLRIATPDGSAAFRPWCDDFRPTNVLIGGSGPDGEVKVAAAIDWEFTYAAPTQFVLDPPWWLLFETPEMWKPSGIDEWSKAYELQLDIWLKVVEEQEKGAVFLDGVTLSAHMRESWETGRFWLNYAARKSWAFDAVFWNFLDERFFGARDSRVPDEELWKTRIDLLGREEQQAMGPFVKRKVEESRERILAEWEPAEARRQLSELLVEPITQGRRSRRRLASGIVVVSSSCIITYISIDGLKELGMAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIX0</accession>
    <name>E3QIX0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_05952</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094828.1">
        <property type="nucleotide sequence ID" value="XM_008096637.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIX0"/>
    <dbReference type="STRING" id="645133.E3QIX0"/>
    <dbReference type="GeneID" id="24411317"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05952"/>
    <dbReference type="eggNOG" id="ENOG502STPC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_167691_0_0_1"/>
    <dbReference type="OrthoDB" id="2565331at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40636">
        <property type="entry name" value="CSBD-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40636:SF1">
        <property type="entry name" value="CSBD-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ30808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="91" mass="8717" checksum="B7C9022DFD7BEE86" modified="2011-01-11" version="1">MPIGNNDQNTGVTGGAKFVTSALGNTVGGLTKTVGNVTSAATTGLGDTITSATGSAGRPIGDGITNLGQGLGGALNQVGKGAEDAGQWKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIZ6</accession>
    <name>E3QIZ6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05978</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094854.1">
        <property type="nucleotide sequence ID" value="XM_008096663.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIZ6"/>
    <dbReference type="STRING" id="645133.E3QIZ6"/>
    <dbReference type="GeneID" id="24411343"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05978"/>
    <dbReference type="eggNOG" id="ENOG502STM3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012879_0_0_1"/>
    <dbReference type="OrthoDB" id="5342924at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="692" mass="77083" checksum="B7724203289C5363" modified="2011-01-11" version="1">MGHHVDADTINNVLQLVAKLHELLIVASLSSIALAMFRRCLVTNGVRLGFLTGGYRVGDLGYMGTTAFWRQGFDTSSPWGILLPGFVVFATILSTTVGPASAVLLVPTLGWYKIDNSIAFGNITLPLRYSWNKENIWFAGRHDAPSECKTVKGIYNDYCAAGGFPQISSWLLDFAATDLTNNLAFHSTSADLRRHIVFTHVNDSDGISSTTLLTTPRHFLTGSIGLFEKYIHSSEVGALSREPRYRLNTTRTNPENSEEESILYQPFVQSTCRIHDKHKLVEDQQPVFYPVDSLNCFHDDDCEYFQKNRKEFDEGWLTNPNLDVDVSISTNFLVNKKNSSILFLNGQIPDDSSGESKDIVFLCSLIGSWAPSNFSVDAKASDILRSSLSQSSTMRGLYESDSMVEVHTVRFSSAWFQALNPRWNTTNTTSVTALQQIVQTFSSTERQNGITLPVSAPFSRDNKTGAEMFLSKVFGVYLTEGLARSTYKHQNTRVVLNSSSDELAYINLNEQHGYRGGVHKVTPLNSTFRLERWRGKDTPLNGPFEDFQAAFHKDLPIYIVAERHGYGSGQQRRTLHWAQATMGIYLGTVAIYALGVGAMSVLEFFEYEPGGVGVRVLSIIPWSDLQDLMILALKTPVPNDEDLADAGAGVTSSRVWEKTVRARADDERNAQLVLGETNVTRRLDLNGQEGYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJE0</accession>
    <name>E3QJE0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Vacuolar protein sorting-associated protein 17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_06122</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the membrane-associated retromer complex which is essential in endosome-to-Golgi retrograde transport.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the retromer complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 6">Belongs to the VPS17 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ30978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094998.1">
        <property type="nucleotide sequence ID" value="XM_008096807.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJE0"/>
    <dbReference type="STRING" id="645133.E3QJE0"/>
    <dbReference type="GeneID" id="24411487"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06122"/>
    <dbReference type="eggNOG" id="KOG2273">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028982_0_0_1"/>
    <dbReference type="OrthoDB" id="9976382at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030905">
        <property type="term" value="C:retromer, tubulation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06891">
        <property type="entry name" value="PX_Vps17p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000046">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1520.10:FF:000034">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014461">
        <property type="entry name" value="Retromer_complex_Vps17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053055">
        <property type="entry name" value="VPS17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037907">
        <property type="entry name" value="Vps17_PX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015404">
        <property type="entry name" value="Vps5_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47433">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47433:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09325">
        <property type="entry name" value="Vps5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF011791">
        <property type="entry name" value="Vps17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PX" evidence="8">
        <location>
            <begin position="135"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="518"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="16"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="74"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="86"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="122"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="561"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00060860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00073022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR011791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ30978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="605" mass="66296" checksum="3E39EF1698331AAF" modified="2011-01-11" version="1">MDYSASINDEAGASPWGNSPGSSPRPNQSNFASLGADLSGDRPGSPFGYTPSPGDATPQGHEGFGGEQYRRPDTASTQSATEVETQESRTEVGSEARSVESPGPELPQKSQEQGGPPNAGGQSSRDQQPRKPQQPQFRLQAKITGLERTGKKDPILRFDVHTNLPRFRTTQYRDVRRFHSEFVKLAEHLISANPECLVPTVPPAVTSAGAGTDEDEARVKALLQRWFNYVCSNEVLMRDDEMVLFVESDFGYSPMVKMKQPATGVRRKILKQFAPPPDDTPELQEARPIVKLFYLGTMDAGHKVDKLVKSRRGLGLAESDFGVKLGSMHIQEPHQGLANAYRKLGKIVQTVGDYHAAQATAEATTIGDPFQYHSQDAFIVKETLTNRQILIREFLQAQENTRSKLNAADRLKASSNVRREKVDEAITALDDARQNETYLYQKTTRVTQNLVQERRKWFARTAADLRLSIREYVIREIEAERRALAVLESVRPDIRAIDASGGLSRLGRESHPPVRRAAVAASQGPKGDAWSGVPRRTDTMNRSVSGSLIAGLPEEGDGHDGQGTGQNQGLGIAGGRASLSGVAEEDDEDRVDARNAASRLATSTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJY4</accession>
    <name>E3QJY4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_06316</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the major facilitator superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697353">
        <property type="protein sequence ID" value="EFQ31172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095192.1">
        <property type="nucleotide sequence ID" value="XM_008097001.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJY4"/>
    <dbReference type="STRING" id="645133.E3QJY4"/>
    <dbReference type="GeneID" id="24411681"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06316"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_11_2_1"/>
    <dbReference type="OrthoDB" id="5141738at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000082">
        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF74">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="129"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="217"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="247"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="322"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="361"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="400"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="428"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="461"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="493"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="90"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="543"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="14"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="543"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ31172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="568" mass="62772" checksum="E22F199EBB93E8DD" modified="2011-01-11" version="1">MPTPRESVLVDGQSLPNLQHSISSLPGTARRIGEDEARSIYEARAEEQGLDKKPAASPNSSGDEDEKTIISWDEGDPENPYNWSHIRKLLILCLTMMQVINSTMGSALPSNAIPFITAEWDVTNEQQKVLPISVFLIGYVFGPVVWAPLSEHLGRRTLTIITFIMFTIWTMACALAPNWPAFLFFRFFAGVFASSPIAIVAGILADIYGDTQSRGRAMTAFMVTTAFGPLFAPIVSGFCSPTIGWRWSFWIALIYAGVTLVPIILLPETYGPILLCRRARRIRKLDPSANVIAPREMERTDLKQLATVVLTRPMRMLVSEPLVTCTCAYLALVYTIFYMSFQAFPIIFQKLYGLSPGVSGLAYLPIGGGSIIAVPVFIGWEQRHLRAQRDGSRWAKQEELRRLPLACVGGPLFFISLFWLGWSSREGISFVVPMLAGIPFGAGFMLIFIALLNYLTDAYEIFAASANAAASGSRSLLAVVLPLATTRMFNELGIAGACSLLGGMSAVMCVIPFIFIWKGEQIRAGSRFCIALRERKAEMERKVEEQKQREARRASRQGILAGQKAEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QK45</accession>
    <name>E3QK45_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_06377</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697354">
        <property type="protein sequence ID" value="EFQ31233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095253.1">
        <property type="nucleotide sequence ID" value="XM_008097062.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QK45"/>
    <dbReference type="GeneID" id="24411742"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06377"/>
    <dbReference type="eggNOG" id="KOG2504">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_1_2_1"/>
    <dbReference type="OrthoDB" id="6499973at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF305">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="51"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="251"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="289"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="317"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="341"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="378"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="416"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="22"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ31233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="446" mass="47798" checksum="415DA08FCC0B5B34" modified="2011-01-11" version="1">MDPEKGAANPVHPDAPPASIQDGHETDHSSDDAPHGPVTKAEEQTCDGRDAWITVAASSLTMFVYLGVIYSWGIMQVRLVETAGSSLTTLTFVGSLATSFMICFSIVSDKIVCRVGYRLSALVGGVFMGLGEVLASFATRHVVALFFLHGLVFGLGGGLCVFSVSTAPMSLFKRRKALAMGFVFGGGSLGSAVMSVATNFLVRDLGVAWTFRILGFILWGVSIPASYFLPQRNSSGKKASRQLQWYRFKQPRFLLLVGGTILACFPLFIPPYFIPIFSRSMGYPKEVGIIILAAWNLASTLGRIMAGWVADTLLGPVESLAICMLFMSLSSLVVWPLSSSIGIFAVYLFFNGVGCGAFFSLTPIAVGATFGAENTLSIIPVIWTTWFCGFFFGTPIASGLYSLSGGADGLENFRPAAYYAGAMAMAGFACVLAMRFTRTHEVTARM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKE0</accession>
    <name>E3QKE0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_06472</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697354">
        <property type="protein sequence ID" value="EFQ31328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095348.1">
        <property type="nucleotide sequence ID" value="XM_008097157.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKE0"/>
    <dbReference type="GeneID" id="24411837"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06472"/>
    <dbReference type="HOGENOM" id="CLU_2236402_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="105" mass="12295" checksum="5EC7EBDC442F1CB0" modified="2011-01-11" version="1">MISSCHAARLIALHRVTLHHTASPYRGWHDWIDQEQTREKNGVLSHKKLSSEGYREAAFGLYKVWSLIFYLSWGWLVGLISRSRRGIRDIWESFSLDILFHSHSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKV3</accession>
    <name>E3QKV3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Serine carboxypeptidase S28</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_06635</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S28 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697355">
        <property type="protein sequence ID" value="EFQ31491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095511.1">
        <property type="nucleotide sequence ID" value="XM_008097320.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKV3"/>
    <dbReference type="ESTHER" id="colgm-e3qkv3">
        <property type="family name" value="Prolylcarboxypeptidase"/>
    </dbReference>
    <dbReference type="MEROPS" id="S28.004"/>
    <dbReference type="GeneID" id="24412000"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06635"/>
    <dbReference type="eggNOG" id="KOG2182">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023630_1_0_1"/>
    <dbReference type="OrthoDB" id="1735038at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070008">
        <property type="term" value="F:serine-type exopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008758">
        <property type="entry name" value="Peptidase_S28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010">
        <property type="entry name" value="PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010:SF23">
        <property type="entry name" value="SERINE PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05577">
        <property type="entry name" value="Peptidase_S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179831" evidence="6">
        <location>
            <begin position="18"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ31491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="541" mass="60086" checksum="EDD35A0038AD4085" modified="2011-01-11" version="1">MKVPLALLTCLTAAAQARFAFRPTQPPFKADDVDGLLSKRALGSFEQLIDHNDPELGTFQQRFWWNSTFWKGPGSPIVLFTPGEEDAEEYTGYLTDRALTGAIAKEIGGAVIMVEHRNWGTSLPYALQDTKNLQQHTVANAVQDLVYFARNVELPFDTNSSSNAPQAPWVYTGGSYSGYLAAAIAKLAPGTFWAYHASSAPVEAINYYWSYFLPIQEGMPKNCSRDFERIIEHVDTVLNNGTKDEIYALKKKFLMQDLPHDDDFASALSSPLGLWQSIQQYDGYSEFYQMCDTVEGVAGNATSGNSTAPGPDGVGLPKALDNLAAWWRANMIKNVCASYRYKDWQDPMSVACWDTYNASSPGYTDWSAANVFGRTWYWMLCNEPLFYWQTGAPEDRPTIVSRLTTPEYFQRQCGLFFPKQGEYTFAADLGKTADDVNKVTGGWDFTNTTRLVWTNGGFDPWRSASVSSELRPGGPLQSRPGAPVNLIPGSRHCNDLLTENAEVNADVRAAVTAEVAQLKTWVAEFYNGKVTQKRRIAATSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLB8</accession>
    <name>E3QLB8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fungal specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_06945</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697356">
        <property type="protein sequence ID" value="EFQ31656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095676.1">
        <property type="nucleotide sequence ID" value="XM_008097485.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLB8"/>
    <dbReference type="STRING" id="645133.E3QLB8"/>
    <dbReference type="GeneID" id="24412310"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06945"/>
    <dbReference type="eggNOG" id="ENOG502QQXX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006632_1_1_1"/>
    <dbReference type="OrthoDB" id="2264294at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001080">
        <property type="term" value="P:nitrogen catabolite activation of transcription from RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF4">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN DAL81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="69"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="103"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="133"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ31656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="665" mass="72893" checksum="40B1ABB61B81F186" modified="2011-01-11" version="1">MDTTPAPCGIPVSAGIDPATIQALSSSAHIPSFESHPSAASGQSSAATAAAAAAAAVAASTTGAAQSRPCDICRQRKTRCVREEGLDKCVMCSFHRQPCTYLRGPLPRKRRKATDPPEQRPSTNGSVSAPAAPAGPPPAPVPLDPQEEITHPSPELLEALSPSLAGSEHAATFNQPSLLDGTLGLHLKTHSEYVGNTNHREPSLLDLHRPHDPAVRSVRRLDESTVFLIHRDRETSSEPQRIADLDAIEKVVHPLGSTLVNLYFRIVHPSFPVLHKKVFLEKYARSYHEFSPPLLAAVYLLALDWSLYDRTLATSSWQPDQAALEALALRTMSDDMKRPKISTLQAGLLIQQRFRNNTWTFIAQLIALAQGLGIHVDCSDWAIPDWEKGLRRRLAWALFMQDKWGALVHGRPSHIRLDEDWDVRPCCVEDFPENAADEEHDPEGSAEVVVGRELFLRQIELSLILSDVLSTFYTAKATRRGGTLDQIGTVGVAELAKPIVMMLREWYAKLPEALQLQETRLKKLSANGSLHLAYISIDLALHRSLVRNISSSAPPELRAAIRAGARARLASASSIIANLQMEHIQSFWGFAAPAQLAGIGSFAGLLWATSDDDAEAMYYADRVEEYLWSLRVRAQAAPFVREALRMLESDVSGLDAVRAAAEVKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLK5</accession>
    <name>E3QLK5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_06718</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697357">
        <property type="protein sequence ID" value="EFQ31743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095763.1">
        <property type="nucleotide sequence ID" value="XM_008097572.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLK5"/>
    <dbReference type="STRING" id="645133.E3QLK5"/>
    <dbReference type="GeneID" id="24412083"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06718"/>
    <dbReference type="eggNOG" id="ENOG502R610">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_12_3_1"/>
    <dbReference type="OrthoDB" id="4682787at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF108">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="246"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="61"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ31743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="395" mass="43848" checksum="4EDBF803E9264F50" modified="2011-01-11" version="1">MTNSTGPIGAAPPPPGVTPDFDNPRDVGHTSHIVFTSFIQAIVVLFFALRIYVKWELSDWMDLHRHHEFDRSYECVSSTEGAEWMAINGWMYIGSLLYSPAAFFTKISILLLTVRVFSVDAAAARILHLLPFFFLICYIPAEIAKACVCIPVQSFWDQSMTDFKCIDQTKLFLYDSSLSAFSDLIILIVPMVLASRLRVSTLKKIKIVGLLGTGGVAVAVTIYRLYLVNKYDNTKDPTMDFVPLDWTVAGELGIGIVCACFPSVNHVLEERAARTALESKEPQGLSRWWRETSKRCSDALSSWGQAHGYRMPAFRRTEEEQKCDSVGGVSALPESENGEPKKLDYDVELAAVSASHLDPHPGELVDSGVGGYGQNCLTPLPIIRRSSPFKINCRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QM09</accession>
    <name>E3QM09_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07041</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095917.1">
        <property type="nucleotide sequence ID" value="XM_008097726.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QM09"/>
    <dbReference type="STRING" id="645133.E3QM09"/>
    <dbReference type="GeneID" id="24412406"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07041"/>
    <dbReference type="eggNOG" id="ENOG502RS8C">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_717851_0_0_1"/>
    <dbReference type="OrthoDB" id="5242705at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394">
        <property type="entry name" value="DUF3176 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394:SF5">
        <property type="entry name" value="DUF3176 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="256"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="354" mass="40273" checksum="B1D182818E692B64" modified="2011-01-11" version="1">MELDVECPFTNCTWPIMPTLAVCGECNSVDVRTICTDKSQTCLYSLPSGTSVDISHNAPATERFRMASSRPGIHHHFNSTLQTYISVFDVLWVTKTRKETKTMGQECALWFCMMSYNITVTEGRSNQTVTKIWNTTQFEASNSAHDDEYVFVDIPVDMNATSTSRYSTSRVALEALRRFIDPLVEGTYEKQYTIINFSSDWAEGMYNARFNLPSWINRFSTSLTNEVRLHGQVRNKERHQYSGQAYKIAQMIIVEWKWLLFPTGLIIISIYYLFHTIIRGARDGISVWKSDSLPMLFCRIDASILARVGDGMDVPNGLDNAVGEVKVCLLREEDGDWVFKPIESEESSSESDAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QM11</accession>
    <name>E3QM11_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_07043</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095919.1">
        <property type="nucleotide sequence ID" value="XM_008097728.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QM11"/>
    <dbReference type="STRING" id="645133.E3QM11"/>
    <dbReference type="GeneID" id="24412408"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07043"/>
    <dbReference type="eggNOG" id="ENOG502SBR1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_776137_0_0_1"/>
    <dbReference type="OrthoDB" id="3180714at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053185">
        <property type="entry name" value="SET_domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332:SF4">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="219"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="159"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ31899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="400" mass="43885" checksum="6881C1F2C7B94CD5" modified="2011-01-11" version="1">MSQSSVLATSMDQGGSFPKDELDPVFISPEMLVTHLQDTRCCSGSYDDLYVGIGSPMPKARINPMSLDAMLDIDPEPVNSILELTEPLEQVKNGLREFAILIGMKLPPIAIRDITWKTVHVAQNITVGCEPEEVEAYGIDYDVNDNDDDDDDDNHTILSSDVGSSNSCSHSDGSGAAFLIGLLGSIDNPVFLEAADLPLLTTFEGSDGTTERSVIFANEFFEIRRSPTAGWGAFAVKTLSRGDQILVEKALYHATHENVTSSVQDLPEKERAIANDMFAYYSRDGETLQEAIWSTNSFVSRLPTKSSAGAVNGIRPGSQDVAGLFPVAGRFNHSCFPKVSFRFRPEHDALVFTVRDWIIEAGDELTISYGKDPSVLYYKYGFGCECGYCRGFDPATSEWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMC4</accession>
    <name>E3QMC4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Methionyl-tRNA synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_07156</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096032.1">
        <property type="nucleotide sequence ID" value="XM_008097841.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMC4"/>
    <dbReference type="STRING" id="645133.E3QMC4"/>
    <dbReference type="GeneID" id="24412521"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07156"/>
    <dbReference type="eggNOG" id="KOG2241">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009710_6_6_1"/>
    <dbReference type="OrthoDB" id="19141at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017102">
        <property type="term" value="C:methionyl glutamyl tRNA synthetase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004812">
        <property type="term" value="F:aminoacyl-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd10304">
        <property type="entry name" value="GST_C_Arc1p_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02799">
        <property type="entry name" value="tRNA_bind_EMAP-II_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000199">
        <property type="entry name" value="tRNA-aminoacylation cofactor ARC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053836">
        <property type="entry name" value="Arc1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051270">
        <property type="entry name" value="Tyrosine-tRNA_ligase_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11586:SF33">
        <property type="entry name" value="AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11586">
        <property type="entry name" value="TRNA-AMINOACYLATION COFACTOR ARC1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21972">
        <property type="entry name" value="Arc1p_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 3" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="GST C-terminal" evidence="5">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="TRNA-binding" evidence="6">
        <location>
            <begin position="212"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="139"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="182"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="188"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ32012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="405" mass="42996" checksum="1C9740056E2DC16B" modified="2011-01-11" version="1">MASSNTTYTPNEETEIQQWLTTAARLQQAGAGADASPILDTLNSHLSTRTTLLGTKPSKADTALYDAVRPLVAAWSPEQRTGEKGYPNIVRHLDFVQNYPAFAADVKPEDKVAVDLDNVLYVKPPVDAKAEKERLKKEKAAAAAGGDKAALPDRTKDAGKDKSAGEKVKEAVVDAKDKVKAAVAGGDAKPKKEKKEKAPKPQKAPAPAAPLSPALIDLRVGHILKAIKHPEADSLYVSTIAVGDEPNDDTTEYEGQVCRTVCSGLNGLVPLESMQGRKVVVVCNLKPVKMRGIKSCAMVLAASPKLKEGETDDHKGPVELVTPPADAKAGERVCFQGWEGEPEGVLNPKKKIWETFQPGFTTTDDLAVAFDAGVVEALGKQGVAKLVTKSGGLCTVPSLKDAVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QML4</accession>
    <name>E3QML4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07246</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096122.1">
        <property type="nucleotide sequence ID" value="XM_008097931.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QML4"/>
    <dbReference type="GeneID" id="24412611"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07246"/>
    <dbReference type="eggNOG" id="ENOG502T56H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1098423_0_0_1"/>
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    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="277" mass="31346" checksum="62E45E2C78244195" modified="2011-01-11" version="1">MARTTFDISSSHTLSFVERLIQPHLPNPKVIAAKLRQMPKDRSETRRGPRVTGQPYIDTSILRGGRASPERERADENKHGVPRDVAGKTPGGGTRHHCPQRGQHTSDLLCLKKGCMIKCTGCGICISRYNGAKCRACAARETARLREEKEAREAQRKTDAKHAKKGKSPQVKFFLASYPSGIRKRTGRVGMRTLGRSFRRSRSQDYGRFSRSQLSGEESVDYDEMDEDESEWEGVQEDVDRQEDNETTAKEAHHLQLLEEEATLQRKIRESLLNLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QN78</accession>
    <name>E3QN78_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNA repair protein/CtIP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_07460</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697361">
        <property type="protein sequence ID" value="EFQ32316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008098145.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QN78"/>
    <dbReference type="STRING" id="645133.E3QN78"/>
    <dbReference type="GeneID" id="24412825"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07460"/>
    <dbReference type="eggNOG" id="ENOG502S92Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="5801062at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010792">
        <property type="term" value="P:DNA double-strand break processing involved in repair via single-strand annealing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013882">
        <property type="entry name" value="Ctp1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033316">
        <property type="entry name" value="RBBP8-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15107:SF0">
        <property type="entry name" value="DNA ENDONUCLEASE ACTIVATOR CTP1 C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15107">
        <property type="entry name" value="RETINOBLASTOMA BINDING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08573">
        <property type="entry name" value="SAE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA endonuclease activator Ctp1 C-terminal" evidence="6">
        <location>
            <begin position="583"/>
            <end position="693"/>
        </location>
    </feature>
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            <begin position="75"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
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            <begin position="171"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="238"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="447"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="494"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="678"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="117"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="76"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="172"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="278"/>
            <end position="290"/>
        </location>
    </feature>
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        <location>
            <begin position="325"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="390"/>
            <end position="402"/>
        </location>
    </feature>
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        <location>
            <begin position="457"/>
            <end position="470"/>
        </location>
    </feature>
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        <location>
            <begin position="502"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF08573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ32316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="728" mass="81901" checksum="5FECBC91C5E76DD2" modified="2011-01-11" version="1">MESWSPESRAAVQIAFNALRETISKEAQNEVEHRLKEDSRTRALLTDELEILRSRSAEVDRLEEENRKLRTKLLQFHQQTRSTESSSDSPRPNYVSRDQGTNTDPMSIATFEKGSELEQVLRESQKLRRKYNALDQNFKILKLEFNKRRNENKKWEEYATSLEAKIKPFKQSRRELDENTHSTEALPEPTRPQAVLTSGYASDPGDGPASTRWTAESTRHIPLEPVPATTTSTAITAIIPPGKGTTRDPTPGESTEGEATDGSKDEDIITLPPLRQPPKTDSDIRIKPEPSSDGPVVVSERFVGKRKHLDDCSTEQQGRRRIKVESSNITGGPSTSQLQQESMDLDEVGQKLSTPRKNRILPTTVVESERMDTGRAKTTAPLFVRPDNMGTPTARSLDSSAVLTPVNPNARPVRPYELKTVEKPIKKGLSQGIESLAEDGLAYKKSGRGVPAEAQLRTPQPTGRLSTLLNMPSPEQAPAIVRSAPRLRGTQWALADDGPQFPERRELPFSKERRERSKETTAIQNELGETVEHGTPRALARNRSGAHTPSPAVRGSLRAKPMANMRLEDFKVNPKFNDGSDYAYSEVVRSKDDRACLPGCTDMNCCGKQFRAMALAQRNNVERTSASDTKLFEDYLGDRVSITLGMSKAEKDELWVEAKTWQLANELGKHRHRYARRPSPPGFWNADFPTTQEVEDEKSEAEKRERQLIQERYREAMRGGGRWIFRDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNL7</accession>
    <name>E3QNL7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FAM192A/Fyv6 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_07774</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697362">
        <property type="protein sequence ID" value="EFQ32504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096524.1">
        <property type="nucleotide sequence ID" value="XM_008098333.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNL7"/>
    <dbReference type="STRING" id="645133.E3QNL7"/>
    <dbReference type="GeneID" id="24413139"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07774"/>
    <dbReference type="eggNOG" id="ENOG502S6KG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067596_1_0_1"/>
    <dbReference type="OrthoDB" id="75807at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039845">
        <property type="entry name" value="FAM192A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019331">
        <property type="entry name" value="FAM192A/Fyv6_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13495">
        <property type="entry name" value="NEFA-INTERACTING NUCLEAR PROTEIN NIP30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13495:SF0">
        <property type="entry name" value="PSME3-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10187">
        <property type="entry name" value="FAM192A_Fyv6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAM192A/Fyv6 N-terminal" evidence="4">
        <location>
            <begin position="38"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="116"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="116"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="168"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="178"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="207"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ32504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="266" mass="28047" checksum="B426A6A343CED466" modified="2011-01-11" version="1">MTRFVSAGAIDVKTGEAVVAEETKNGDGTTAAAAATTAIEAKKKAEWEIVQRELEAERKRREEARVKSVEGGEKSLYDVLQANKAAKQAAFEEANKIKNQFRALDDDEIEFLDEVREAKRAEEERVRRETEEGLAAFRRAQGQGQKRPGDGGDDDDDASEGGGGADGGAAAAAGVSGARDDGAGKAEEEWAVGPRKRRKREKGGFGVRRDAAAERKTSVGEKATAATAIGGGEKKEDAAEGSPRAPPPANGKKLGLVAYGSDSDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNP0</accession>
    <name>E3QNP0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fungal specific transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_07667</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697362">
        <property type="protein sequence ID" value="EFQ32397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096417.1">
        <property type="nucleotide sequence ID" value="XM_008098226.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNP0"/>
    <dbReference type="STRING" id="645133.E3QNP0"/>
    <dbReference type="GeneID" id="24413032"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07667"/>
    <dbReference type="eggNOG" id="ENOG502TA49">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_741874_0_0_1"/>
    <dbReference type="OrthoDB" id="3469466at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540:SF10">
        <property type="entry name" value="SIGMA-70 REGION 2 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540">
        <property type="entry name" value="TRANSCRIPTION FACTOR (ACR-2), PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ32397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="373" mass="41247" checksum="DA0DA173B8BDAB85" modified="2011-01-11" version="1">MSDRQTFLALVAGGSYRLRFLTNSIEDNRACFKAQNQIARTVRQQLSAGITTVSDIVVFSLITISLDQNPYLLSLAPEDRYAGDFDTPVKSLGGLLWLGLMSYEPSLQTMWMHLLRARNPSLSNKAPGLADGLQSSDLLRASALLQRPDLEMQEAYCLQEEEAAAARPDASEVDAFHVDAHFKAILLDIKACCRLIDAFFGPVHPLSPEATGFVQFRNLILYRLLSLPPGVAEICRLAALVFNYTVLYPFPDPRILWKLCRQLEGILSDPQQTTNEDAGLLLWAAVIGGIAAARTVAYDSFASSVNKFAALLGLEDWPQTVAHLESFIWHERVCGVGGRTLWARARALALSNKSYGYLYLTSRPKATIEECFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QP92</accession>
    <name>E3QP92_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Biogenesis of lysosome-related organelles complex 1 subunit CNL1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">CNO-like protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_07824</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1), a complex that is involved in endosomal cargo sorting.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the BLOC1S4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697364">
        <property type="protein sequence ID" value="EFQ32680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096700.1">
        <property type="nucleotide sequence ID" value="XM_008098509.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QP92"/>
    <dbReference type="STRING" id="645133.E3QP92"/>
    <dbReference type="GeneID" id="24413189"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07824"/>
    <dbReference type="eggNOG" id="ENOG502S5Q7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096905_0_1_1"/>
    <dbReference type="OrthoDB" id="5424991at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031083">
        <property type="term" value="C:BLOC-1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007032">
        <property type="term" value="P:endosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034455">
        <property type="entry name" value="CNL1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39145">
        <property type="entry name" value="BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT CNL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39145:SF1">
        <property type="entry name" value="BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT CNL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="140"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="156"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ32680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="181" mass="20272" checksum="715AEFB50BD6C6BE" modified="2011-01-11" version="1">MSTTQVNAVPDTQLGLSYEEIQLLRQGQAALAQGAGGGGGGIQLGLLLLDSTSLAALGRYFDRVMGQIEQQIVYLSEQSQMFTMAQFDRAGNLVEGADAEIARYHDLLRQLDELELDFDRIRHIKDIVRGYRSRVEDMERELAASASSSSSSSRHREGHRSSHRHSHSHRHGHESSRRHRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPV6</accession>
    <name>E3QPV6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_08027</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-dependent oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697365">
        <property type="protein sequence ID" value="EFQ32883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096903.1">
        <property type="nucleotide sequence ID" value="XM_008098712.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPV6"/>
    <dbReference type="STRING" id="645133.E3QPV6"/>
    <dbReference type="GeneID" id="24413392"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08027"/>
    <dbReference type="eggNOG" id="KOG2495">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019845_6_2_1"/>
    <dbReference type="OrthoDB" id="202203at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004174">
        <property type="term" value="F:electron-transferring-flavoprotein dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735">
        <property type="entry name" value="APOPTOSIS-INDUCING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735:SF3">
        <property type="entry name" value="FERROPTOSIS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00469">
        <property type="entry name" value="PNDRDTASEII"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="5">
        <location>
            <begin position="12"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ32883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="389" mass="41509" checksum="EC768F45587EFE73" modified="2011-01-11" version="1">MAQPSDSPVKKHVAILGGSYGGISTAHYLLRHALPRLPRPEEYQVILACPRALLSDDMFPQHKLFVGISSMFESYAQGTFLFLHGTATALDHVNRTVTIDMAGEKGVKILDYHAVVIATGASTPSPLLGLNSASEDLRQSWAVFRKALPAAKSIVIPGGGPAGVETAGELGEYLNGQSRRLQTSLGVPKATITLVTSASEILPALRPAIARKAESYLAQVGVTVRKGVWVCSVRPAAAGAGEVAATAAVILDSGETLDADLYILALVSTNSSTLRVDPAGPQVYAVGDASSYARPAVHNILAAVPVLCTNLRRDLLLASENPEEAEGQDRLFTEDPRENHLVPVGRSKGVGAAMGYQLPSFLVCMIKGRDYWLWTTENLWSGKQWAKEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQ19</accession>
    <name>E3QQ19_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nucleoside phosphorylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_08101</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697366">
        <property type="protein sequence ID" value="EFQ32957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096977.1">
        <property type="nucleotide sequence ID" value="XM_008098786.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQ19"/>
    <dbReference type="STRING" id="645133.E3QQ19"/>
    <dbReference type="GeneID" id="24413466"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08101"/>
    <dbReference type="eggNOG" id="KOG4177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_34_22_1"/>
    <dbReference type="OrthoDB" id="20872at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="entry name" value="Nucleoside phosphorylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053137">
        <property type="entry name" value="NLR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082:SF11">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082">
        <property type="entry name" value="ATP/GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="Purine and uridine phosphorylases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleoside phosphorylase" evidence="2">
        <location>
            <begin position="82"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ32957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="359" mass="39637" checksum="971899081361E142" modified="2011-01-11" version="1">MSNDVPSMVTSGRKRGHSRYSDDSPRPDIAKRAKTLLDCNGDDRERRHVDYTVGWICALHSELAASRAILDRQHRDLFKIANDPNEYILGNIVGHNVAMACLPLGQYGTNNAAIVASNMRSSFPSIRVGLMVGIGGGVPGDGFDIRLGDVVVSTTVIQYDLGKILPGERVQRTAIPKVAPHHLLNAVAKLRALHESIPSGVPSILEEMFHHHPRMAQEYAYPSHCEDRLFNSTYDHGKLADCKHCDPLEVQPRLQRQNNLPRIHYAKELGVICFEMEAAGLVDQFPFMPVRGICDYADSHKNKQWQRYAAATAAAYTKELLSTMAPSMVEAILAADVREPTTCKKATRSQSAFVGAAEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQA2</accession>
    <name>E3QQA2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08184</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697367">
        <property type="protein sequence ID" value="EFQ33040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097060.1">
        <property type="nucleotide sequence ID" value="XM_008098869.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQA2"/>
    <dbReference type="GeneID" id="24413549"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08184"/>
    <dbReference type="eggNOG" id="ENOG502T45X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1053782_0_0_1"/>
    <dbReference type="OrthoDB" id="3513892at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910:SF6">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="30"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ33040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="258" mass="29544" checksum="83664D95214E843B" modified="2011-01-11" version="1">MASPSKSDHDRLHEELTSLDLADPTPSPTFHLFSSLPPELRIKIWRLAAPKPAVVERAMNNYTMAYGLRRRVPALLQVCRESRAELLYQADDRRGSRDGQFQLLHLSREHKEEGKGVYINCSDDTLLICRAPQYAVMPDAANFANIRHLAMEWGLRPCWVQNHCHEGVRFVRQFPQLRTLTLLVSFKTYNQLPLGDPGSKHREQTQKRRALREIKGWVLEALAQDRERRATDGNAGAWPSPEVRVVPKTKFWTASATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QR09</accession>
    <name>E3QR09_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">MIF4G domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_08441</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic initiation factor 4G family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697369">
        <property type="protein sequence ID" value="EFQ33297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008099126.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QR09"/>
    <dbReference type="GeneID" id="24413806"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08441"/>
    <dbReference type="eggNOG" id="KOG0401">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1003">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003998_0_0_1"/>
    <dbReference type="OrthoDB" id="514777at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010494">
        <property type="term" value="C:cytoplasmic stress granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016281">
        <property type="term" value="C:eukaryotic translation initiation factor 4F complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="Eukaryotic translation initiation factor subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Eukaryotic translation initiation factor subunit eIF-4F, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.970.30">
        <property type="entry name" value="eIF4G, eIF4E-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022745">
        <property type="entry name" value="eIF4G1_eIF4E-bd"/>
    </dbReference>
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        <property type="entry name" value="eIF4G_eIF4E-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003890">
        <property type="entry name" value="MIF4G-like_typ-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23253">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23253:SF9">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12152">
        <property type="entry name" value="eIF_4G1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02854">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00543">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101489">
        <property type="entry name" value="Eukaryotic initiation factor 4f subunit eIF4g, eIF4e-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="MIF4G" evidence="9">
        <location>
            <begin position="1149"/>
            <end position="1394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
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            <end position="561"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
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        </location>
    </feature>
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            <begin position="1045"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1121"/>
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    </feature>
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            <end position="1450"/>
        </location>
    </feature>
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        <location>
            <begin position="1469"/>
            <end position="1565"/>
        </location>
    </feature>
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        <location>
            <begin position="9"/>
            <end position="31"/>
        </location>
    </feature>
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            <begin position="33"/>
            <end position="45"/>
        </location>
    </feature>
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            <end position="83"/>
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            <end position="116"/>
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            <begin position="610"/>
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            <end position="652"/>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="808"/>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
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        <location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="8">
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            <begin position="1544"/>
            <end position="1553"/>
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    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
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    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ33297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1565" mass="166534" checksum="2FA465DA00BE30C6" modified="2011-01-11" version="1">MTSTASPQSNPAPNTSAATSAPSYASAAGANKKQASTPLIATGSNPPVVVGGSSAQNAKPSAPSPVNGRQSITPAVPAAPAVAHGSSNNNTMNGNAPDHARKSSVTLSANGPNSFAPNGGPVGGSKPGIQFGYNSPAVAHSTPQTTAAPIPIPGSNNQRVPSPAHSPSPIPQPSASGGRPPSGMAPSNAMTFGSLGSDGDRHMRQASTPQTQAALPAQPGSHIRRESGVSQHSDAAGPNQGPNRQGFQPQGGRGRGFNPHQPPYNANMGFPPNQQYRNGQGRGGMPPAFHPGRPMQPYPNSPQPARSPALAQSQPGTPNMPPAQMHPMPMATPPQYHYPPPNMAQPQVHPPPFQDVFIPSTLAPPFVPSSKSKKKKNQYQHLEKFPHKSRYTDSSYGMPFDNKPRRFSEHAGQIWVASDRPSLSYHTDLGNPNRVERGHVSSNELSTSSLPSDPQIDISPQSDYYERLLTNAKQQYGYPPQPTQYDQFGRPMYYNQMGYMPSPPGGPPAFQPGFVPPPYHQPAPAAMSRTSSHSERPSSSTGQPSQPVVVSGTPQPQNAQVKAPIVASSSGNFVRPKKSAAIVIKNAAGEAVDFKSIKTPSSPAPSIQQSKTPPIVTSTPTPPPKSATPSHTRADSQATPKTRQEIQDELRAKIQQAKGGEDKAKEEADAKAKAVEEEKKAAEAKAEAEAKAKAEAEEKAKEEARKAEEEAEAKRKADEEEKAKAKAAEEEKAAAEAKAKEEAEKKAAETPAEPAATEEDEMERMIREMEEEDARREKEAAEYNAKKAIEKEAQKKAEEANKATNAAEADRKLREAEREMERLEEEKERKRAEAAGSSVAELLAKTKAGVDEPAKVGDVADKLSNLSIGDSKASTPTEASAPRATPTEKRGAKPSPLNLAPLNTKPVEAPQPSAALQSLKSARFLSVMNQDLYPSGISSPNPALNAAVAKKGKTFKYDAQFLLQFQKVFTEQPSTEFHQQVKSLIGDNDGSRSASTPRAGSGRGGSQRGTTAPANAIGSFRAPSNNVRGTTSAERFAMANAAMGSGGGPVGNMGTFRSFPGPQMVRTPSSSNVGPNSPRTRSARGGGGSRRNDYNPKEAQAAKTMPLTAGMELKPITVSATGWKPTSIGKSTTSGPTPGADHMDPGMVQRKVKAALNKMTPEKFDKIADQILAIAGQSKDESDGRTLRQVIQLTFEKATDEAHWASMYAKFCKRMLDTMSPEIRDENIKDKNGVVVSGGALFRKYLLNRCQEEFERGWKVNLPTKPEDADEGKPQSSEAAMLSDEYYIAAAAKRRGLGLVQFIGELYKLGMLTERIMHECVRKLVDYEGVPDEAEIESLSKLLRTIGSNLDASDKGKALMNVYFDRIQQMMDMPELASRLKFMLLDVIDLRKKGWASKEANKGPKTLDEIRAEAEAAALQKAQENQRGGSQRGPGGRPNMGRGDSRNFSSGYMQAQSNQVGMDDLRRLKGSTGRTASGNISLGPTSMFSSRSNSGRRLGPGGSLGRPGEDSGASSRTGTPPTTQHTNAFSALANLDSENPASPPSTAASPALSKVVPDSTAAESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QR34</accession>
    <name>E3QR34_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Mitochondrial import inner membrane translocase subunit tim23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_08466</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="EFQ33322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_008099151.1"/>
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    <dbReference type="STRING" id="645133.E3QR34"/>
    <dbReference type="GeneID" id="24413831"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08466"/>
    <dbReference type="eggNOG" id="KOG3324">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063935_1_1_1"/>
    <dbReference type="OrthoDB" id="159299at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005744">
        <property type="term" value="C:TIM23 mitochondrial import inner membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030943">
        <property type="term" value="F:mitochondrion targeting sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045238">
        <property type="entry name" value="Tim23-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15371:SF0">
        <property type="entry name" value="SD19278P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15371">
        <property type="entry name" value="TIM23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="29"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ33322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="241" mass="25221" checksum="025F620068B0FBFC" modified="2011-01-11" version="1">MSSLWDAFSGRKSSQKDAGVPHTPAAQEPTTTFNSPPATTTTQFDPSAGSGVESFLQSSSFADPSQLHPLSGLNKDTLEYLSLDDATLADAPGQSVLPSRGFTDDLCYGTGVTYLAALSIGGAWGLQEGLRRSVNQPPKLRLNSVLNAVTRRGPFLGNSAGVVAITYNLFNAGIGYFRGKHDAANTILAGALSGMVFKSTRGLRPMLISGGIVASVAGTWAVIRSTFFAAPEPVHSERATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>E3QR48</accession>
    <name>E3QR48_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_08480</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697369">
        <property type="protein sequence ID" value="EFQ33336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097356.1">
        <property type="nucleotide sequence ID" value="XM_008099165.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QR48"/>
    <dbReference type="GeneID" id="24413845"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08480"/>
    <dbReference type="HOGENOM" id="CLU_2026555_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ33336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="122" mass="13005" checksum="1C5C159B102FDCE4" modified="2011-01-11" version="1">MEGNERLNLLPNPIPVVNDSIASGTLITVFGSYSPVVLVETTILNPRGGGALSSVRWLAQAAFQNGIFDNVAREAPGVDTRVIVNSGASQIPAGMGRGDAVGAVLRVHTLGWRNMYYWLPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRA4</accession>
    <name>E3QRA4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="22">Multicopper oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">GLRG_08671</name>
    </gene>
    <organism evidence="23">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="16">Cell membrane</location>
            <topology evidence="16">Single-pass type I membrane protein</topology>
            <orientation evidence="16">Extracellular side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697370">
        <property type="protein sequence ID" value="EFQ33392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097412.1">
        <property type="nucleotide sequence ID" value="XM_008099221.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRA4"/>
    <dbReference type="STRING" id="645133.E3QRA4"/>
    <dbReference type="GeneID" id="24414036"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08671"/>
    <dbReference type="eggNOG" id="KOG1263">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006504_7_3_1"/>
    <dbReference type="OrthoDB" id="2121828at2759"/>
    <dbReference type="PHI-base" id="PHI:2920"/>
    <dbReference type="PHI-base" id="PHI:9074"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033573">
        <property type="term" value="C:high-affinity iron permease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004322">
        <property type="term" value="F:ferroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010106">
        <property type="term" value="P:cellular response to iron ion starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033215">
        <property type="term" value="P:reductive iron assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13851">
        <property type="entry name" value="CuRO_1_Fet3p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13877">
        <property type="entry name" value="CuRO_2_Fet3p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13899">
        <property type="entry name" value="CuRO_3_Fet3p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.420:FF:000022">
        <property type="entry name" value="FET5p Multicopper oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.420:FF:000024">
        <property type="entry name" value="FET5p Multicopper oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.420:FF:000025">
        <property type="entry name" value="FET5p Multicopper oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044130">
        <property type="entry name" value="CuRO_2_Fet3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF361">
        <property type="entry name" value="IRON TRANSPORT MULTICOPPER OXIDASE FET3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-0186">Copper</keyword>
    <keyword evidence="15" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0410">Iron transport</keyword>
    <keyword evidence="14 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="7 18" id="KW-0732">Signal</keyword>
    <keyword evidence="5 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="18">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180727" evidence="18">
        <location>
            <begin position="21"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="553"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="21">
        <location>
            <begin position="29"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="19">
        <location>
            <begin position="154"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="20">
        <location>
            <begin position="362"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00037814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="EFQ33392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="619" mass="66370" checksum="5ABC11CFF5FE6FBD" modified="2011-01-11" version="1">MTGTTVFLTLVSALAGTACAATVSHDFNIGWVTANPDGAFDRPTIGINGQWPIPRIDVNVGDTVLINVHNGLGNQSTSLHFHGLFMNGSTHMDGPAQVSQCAIPPGSSFTYNFTINQPGTYWYHSHTKSQYPDGLRAPLIVHDPKSPFIGKYDEEVVVSLSDWYHNQMADLIPGFMSKGNPTGAEPVPQAALMNDTQNLTVAVQPGKTYLFRLVNMAAFAGQYVWIEGHNISIVEVDGVYTEPAEASMIYVSAAQRYSFLVKTRNDTTSNFAIVGSMDTSLFDTIPAGLNYNVTGWLVYDTSKPLSPPATVDTFAPFDDMTLTPHDRQPLLPEPSRTVELDVIMDNLGDGANYAFFNNITYKAPKVPTLYTALSAGSAATNPEVYGTYTHSFVLERGDVVQVVVNNLDSGRHPFHLHGHEFQALYRAPEGGGTFASANVTEAGFPAMPMRRDTLVVWPNGNIVLRFRANNPGVWLFHCHIEWHVTSGLLATFVEAPLDLQKTLSIPQNHLDVCAAANVPTAGNAAGNTKDFLDLSGQNTPPARLPDGFTARGIVALVFSCITGILGVLVVGWYGLAKTENGPSRVGYAGSASVAQTGDGQKEETVMVGAASGGAGAGRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRI4</accession>
    <name>E3QRI4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">GLRG_08751</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="GG697371">
        <property type="protein sequence ID" value="EFQ33472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097492.1">
        <property type="nucleotide sequence ID" value="XM_008099301.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRI4"/>
    <dbReference type="STRING" id="645133.E3QRI4"/>
    <dbReference type="GeneID" id="24414116"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08751"/>
    <dbReference type="eggNOG" id="KOG0583">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002664_0_2_1"/>
    <dbReference type="OrthoDB" id="1928777at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12121">
        <property type="entry name" value="MARK_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14077">
        <property type="entry name" value="STKc_Kin1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000333">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.80">
        <property type="entry name" value="Kinase associated domain 1, KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028375">
        <property type="entry name" value="KA1/Ssp2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001772">
        <property type="entry name" value="KA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF82">
        <property type="entry name" value="KP78A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02149">
        <property type="entry name" value="KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103243">
        <property type="entry name" value="KA1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50032">
        <property type="entry name" value="KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="15">
        <location>
            <begin position="200"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="KA1" evidence="16">
        <location>
            <begin position="1028"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="229"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="596"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="937"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="180"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="235"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="698"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="803"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="837"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="966"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="992"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EFQ33472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1077" mass="118825" checksum="71E56AA917306987" modified="2011-01-11" version="1">MTTAIPASSDSSPAHAPPHPPQSHPHSQPTAVARSLSTQIRPPVSASGPPPKRTSSTNHHHHHHSRSQQLQQRSHSRQSSFTTTAAAAAPPRLVQDLLPQHDYETAKVVSYSKRTVPRDQPPSSSRADASRPQRHSSTTSNQNSHHRISDMPANTAVANNAGPAPVSSHGAPDPRSPGATSSSKHTSRSRTTIPTPSGKWILGKTIGAGSMGKVKLARKEDTGEQVACKIIPRGSTEDGHQTKADKERADQSKEIRTAREAAIVTLLSHPNICGMRDVVRTNYHWYMLCEYVNGGQMLDYIISHGKLKEKQARKFSRQIASALDYCHRNSIVHRDLKIENILISKNGDIKIIDFGLSNLFAPRGHLKTFCGSLYFAAPELLQARAYTGPEVDVWSFGIVLYVLVCGKVPFDDQSMPALHAKIKKGLVDYPSWLSSECKHLLSRMLVTDPKQRATMQEVMNHPWMVKGYSGPPDNGLPPREPLTLPLDADVVNAMTGFNFGSPDAIRAQLTRTIESEEYQRAVKLYQREKELPQPARDVEKKRGFGFDFYKRRNSGNSRDTLTAPSSEALQLGNDPLNAFSPLVSIYYLVREKQDRDHLEKNPGVPNAPKEKPAVPEITPPQEAHTNSSAYEMPGERATGGRSRPRARTHGEDEAPDAVKNSQLSPTTPLSPEVPPEPLPKKESTAAGILRRFSTRRRRDPERLDRDRSHPPVVQVHSPSEASAPLPRKSFSIRRGRREREEPDPLPLRSGSSQPQHGELLSPPLSAGGQSPRRKGLGRSTSVNSADMRRRGSTRALNEPPPTSGSDQSTSMDRPQPAQRESQQTRAASMRAKSLGHARRESIQQRRLRREEAREANVPEETDQEHEQGDQSGVSTDRLDSSDLAKPVFLKGLFSVSTTSTKNVTEIRADIKRVLKGLGVDYTEIKGGFLCKHTPSIDLKKVQDPPGSPGQAPPGHRRRFSFGAIRSGDREREDLRETERGPITPRGTGRNGVDQSCSNSDVSVDSVSREAGGSSRRVPGETSTHVQSDLGGSMVLEFEIFIVKVPLLSLHGIQFKRLVGNTWQYKNMADQVLRELRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRI5</accession>
    <name>E3QRI5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cell differentiation family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_08752</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CNOT9 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697371">
        <property type="protein sequence ID" value="EFQ33473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097493.1">
        <property type="nucleotide sequence ID" value="XM_008099302.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRI5"/>
    <dbReference type="STRING" id="645133.E3QRI5"/>
    <dbReference type="GeneID" id="24414117"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08752"/>
    <dbReference type="eggNOG" id="KOG3036">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039962_0_0_1"/>
    <dbReference type="OrthoDB" id="1183224at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030014">
        <property type="term" value="C:CCR4-NOT complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000014">
        <property type="entry name" value="Cell differentiation protein RCD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007216">
        <property type="entry name" value="CNOT9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12262">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04078">
        <property type="entry name" value="Rcd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="21"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="23"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ33473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="365" mass="40528" checksum="02F67C538BE12BFD" modified="2011-01-11" version="1">MMPAQHVYGHHQFNPQADSAWMHQQSNQHHHAQQAAAAAASAVQQQQQQQQQQQHYNRLAGGHSAVPSLGNTHAPDGGHDNISEDNRRTMAYIADLLNESTREAALLELSKKREQVPELALILWHSFGVMTSLLQEIISVYTLLNPSQLTAAASNRVCNALALLQCVASHNDTRTLFLNAHIPLFLYPFLNTTSKSRPFEYLRLTSLGVIGALVKNDSSEVINFLLTTEIIPLCLRIMETGSELSKTVAIFIVQKILLDDNGLNYICATYERFYAVGTVLSNMVAQLVEQQTARLLKHVVRCFLRLSDNARAREALRQCLPEPLRDATFSSVLRDDAATKRCLAQLLINLSDNVVEPPQGGHPGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRR5</accession>
    <name>E3QRR5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UbiD family decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_08832</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ornithine cyclodeaminase/mu-crystallin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697371">
        <property type="protein sequence ID" value="EFQ33553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097573.1">
        <property type="nucleotide sequence ID" value="XM_008099382.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRR5"/>
    <dbReference type="STRING" id="645133.E3QRR5"/>
    <dbReference type="GeneID" id="24414197"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08832"/>
    <dbReference type="eggNOG" id="KOG3007">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042088_0_1_1"/>
    <dbReference type="OrthoDB" id="41492at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000577">
        <property type="entry name" value="Proline utilization protein PrnX, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1780.10">
        <property type="entry name" value="ornithine cyclodeaminase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003462">
        <property type="entry name" value="ODC_Mu_crystall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023401">
        <property type="entry name" value="ODC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13812">
        <property type="entry name" value="KETIMINE REDUCTASE MU-CRYSTALLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13812:SF19">
        <property type="entry name" value="KETIMINE REDUCTASE MU-CRYSTALLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="370"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="370"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="397"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ33553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="464" mass="50768" checksum="BA2F6CDB5B3FC1B1" modified="2011-01-11" version="1">MVLTVLTDDQIKAILANLTADEFEGFRRTISTALHEYSTNTHNVEDGTYHQPERISTDNLKTGATTLYMPSVGPQVVTLSSSKAAQDPSKPSIQPTGAVTLLSPEGQPVGFLHAKTLTAFRTALSSTCLLARRGQVKTVTVFGVGLQAYWHVRLALLVRGSTIRHVHVINRRFSDQARDFLRQFYKVPQHIKEREGWAEATFGILTPGYGEFKRLQKEQIRDADVVYCCTPSTEDLFEAEVLTSHEGRRKGRLVAAIGSYTPQMRELPEGLLLQATKHEKAHWHFHKHAPEGGVVVVDTLDGALKEAGEIIAAGLQPTQLVELGELIMLRRMHEEEADAADADADADAVSIAPSELDKLDFSGTPSIKSAFSGSDGTSASDPRSSVSRDSATGSHNSRGPSMPRRSSSQRSSDKHKKEDALFKWLRDGTVIYKSVGLGLMDLAVGMHMVQLAREKGIGTQVEGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSJ9</accession>
    <name>E3QSJ9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Methyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_08981</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697374">
        <property type="protein sequence ID" value="EFQ33837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097857.1">
        <property type="nucleotide sequence ID" value="XM_008099666.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSJ9"/>
    <dbReference type="SMR" id="E3QSJ9"/>
    <dbReference type="STRING" id="645133.E3QSJ9"/>
    <dbReference type="GeneID" id="24414346"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08981"/>
    <dbReference type="eggNOG" id="KOG1541">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055194_0_2_1"/>
    <dbReference type="OrthoDB" id="2877at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043527">
        <property type="term" value="C:tRNA methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016435">
        <property type="term" value="F:rRNA (guanine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000056">
        <property type="term" value="P:ribosomal small subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070476">
        <property type="term" value="P:rRNA (guanine-N7)-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000017">
        <property type="entry name" value="probable 18S rRNA (Guanine-N(7))-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039769">
        <property type="entry name" value="Bud23-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022238">
        <property type="entry name" value="Bud23_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12734:SF0">
        <property type="entry name" value="18S RRNA (GUANINE-N(7))-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12734">
        <property type="entry name" value="METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12589">
        <property type="entry name" value="WBS_methylT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="9">
        <location>
            <begin position="52"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23 C-terminal" evidence="10">
        <location>
            <begin position="210"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ33837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="283" mass="30683" checksum="10923709876F4B22" modified="2011-01-11" version="1">MSRPEDTLAADIHYNDSEARKYTTSSRIQNIQASMTRRALELLDLKHPSLILDVGCGSGLSGEILSAEGPEDGGPHTWIGMDVSPSMLDIALQRDVEGDLLLADIGQGVPFRAGSFDAAISISAIQWLCNAESSDTSPEGRLTRFFNGLYASLRRGGRAVCQFYPKNDTQRNMITQAAVKAGFGAGLLEDDPETKNVKLYLVLTVGGTAEGGRGGDITNVVEGMDNVDVEDARRKANAQQSGKGEIKKGSKAWIVKKKEQMERKGKVVKSTSKYTGRKRRIAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSS5</accession>
    <name>E3QSS5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mucoidy inhibitor-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_09057</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697375">
        <property type="protein sequence ID" value="EFQ33913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097933.1">
        <property type="nucleotide sequence ID" value="XM_008099742.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSS5"/>
    <dbReference type="STRING" id="645133.E3QSS5"/>
    <dbReference type="GeneID" id="24414422"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09057"/>
    <dbReference type="eggNOG" id="ENOG502QWQ0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010457_1_0_1"/>
    <dbReference type="OrthoDB" id="10068793at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011935">
        <property type="entry name" value="CHP02231"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037291">
        <property type="entry name" value="DUF4139"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025554">
        <property type="entry name" value="DUF4140"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02231">
        <property type="entry name" value="mucoidy inhibitor MuiA family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31005">
        <property type="entry name" value="DUF4139 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31005:SF8">
        <property type="entry name" value="DUF4139 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13598">
        <property type="entry name" value="DUF4139"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13600">
        <property type="entry name" value="DUF4140"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4140" evidence="3">
        <location>
            <begin position="19"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4139" evidence="2">
        <location>
            <begin position="304"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="532"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ33913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="762" mass="84231" checksum="8752C97790F07BA8" modified="2011-01-11" version="1">MDVIHHKEYHVCDLSTKSVTLFPTRAQIFREVKNLPLKPGTNEVTIIGLTPTVDESTIKVDGTGSAVITDIAVDLLPNRDIFEDIYPDSDDDVPDAESEAEEESADGTSESPELGSLRSRIRQLRSEERSAKEVVDSAASRLKMLDAYGISLDRKESIDIAESIETYRAERERIFRDHMAGVARGQANTELLSASLKEESRLFKQQKKGAAEAAKERGKALKDKARRKHKNAKRREERQREKQRVRKERESFWPKLCYSVRVTLEAAVLTPVSSRRTSISSDTVQASAATSGKETEVADLKCDLTLSYVTSSASWTPSYDLQLFTTNNTGTLCYDARITNETSETWSNCKVVLSTSQAMFSGLENSIPTLKPWSIKLAPKDVGAGENGILDSLDERQQRRDWWNVQKRTTHASKPRHHLFGVENSGSSASPEALRSYQEGLMVLEQQNKGRLLLQRAPQHGLQNQMQLQQQQQQQMQIHPTQLAQMAAARRASATTKGFEEHEGDSLDLSAWLSQDENVDFQESTVEETGFTTTYDLPGTKTLPPRPTPSKQRVARVGFSNVQFSHTVVAKYKPVAYLKAKIRNNSRLTLLRGETGLTLDGTFLGRARLPRCSDGDMFMLGLGVDPAIKVNYPKVDVRRATTGLFSKEDSSVYTRSIVVANTRAAAGKPVSLLVLDQVPVSEDERLKVDVLVPKGLVVNGSSVPAGLPAREGKDDVNWGTATASLKKAGQIDWQVTLNAGKAVRLGLEYVVALPSGNSAVEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTX5</accession>
    <name>E3QTX5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7136 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_09457</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697379">
        <property type="protein sequence ID" value="EFQ34313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098333.1">
        <property type="nucleotide sequence ID" value="XM_008100142.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTX5"/>
    <dbReference type="GeneID" id="24414822"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09457"/>
    <dbReference type="eggNOG" id="ENOG502SY9I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086713_0_0_1"/>
    <dbReference type="OrthoDB" id="4796490at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055560">
        <property type="entry name" value="DUF7136"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23584">
        <property type="entry name" value="DUF7136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180809" description="DUF7136 domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7136" evidence="2">
        <location>
            <begin position="28"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ34313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="260" mass="27536" checksum="490CA9685629E595" modified="2011-01-11" version="1">MLSERIYLLGASLLATCLQLVSAQLPADAIELDLVFPRKDGKYGETSNGYPVLLNVQNPNVAYKYGYNFVWDIYSRNKNSYLRTAAHGVMGASIGNASTFGNGPFLEVGKTGHLAAGDYTFAWVFGMGAQCEFTEQPDYSEYNLNPRIANGSFDFVVESSGKEPTFTKTCPTAIGSMSYASTTTYNSEATSVCGVTASVTHDSQPCSATVSDDQATSVYSALGYAAATGSSKGAAPYSCRQPAFHVVVITGIVAAVAIFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUM5</accession>
    <name>E3QUM5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">glutathione transferase</fullName>
            <ecNumber evidence="2">2.5.1.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_09707</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>RX + glutathione = an S-substituted glutathione + a halide anion + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16042"/>
            <dbReference type="ChEBI" id="CHEBI:17792"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="EC" id="2.5.1.18"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.18" evidence="2"/>
    <dbReference type="EMBL" id="GG697381">
        <property type="protein sequence ID" value="EFQ34563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098583.1">
        <property type="nucleotide sequence ID" value="XM_008100392.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUM5"/>
    <dbReference type="STRING" id="645133.E3QUM5"/>
    <dbReference type="GeneID" id="24415072"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09707"/>
    <dbReference type="eggNOG" id="KOG0867">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011226_14_2_1"/>
    <dbReference type="OrthoDB" id="422574at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051:SF20">
        <property type="entry name" value="GLUTATHIONE TRANSFERASE 1 (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01151">
        <property type="entry name" value="Main.2:_Nu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="5">
        <location>
            <begin position="6"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="6">
        <location>
            <begin position="93"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ34563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="221" mass="25548" checksum="B0959E1B4E0F847C" modified="2011-01-11" version="1">MQPIRLWMAGPKESAGPNPWKVLFVLEELGLPYELKVIHISKVKSPPLTDLSTNGRVPVIEDPNRDLVLWESGAVITYLVQEYDKDKKLTHAEGNEIHHQNQWVYFQTSGQGPYFGQAAWFKIHHPERIQSAIDRYLNEIHRVLGVLNKALEGKEWLVGEKMTFADMAFVPYNSLLHLAFGCDPDESLKDYPNVDAWHRRMLSRDSWKKVMELKNTLEINT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUQ0</accession>
    <name>E3QUQ0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">lytic cellulose monooxygenase (C4-dehydrogenating)</fullName>
            <ecNumber evidence="15">1.14.99.56</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">GLRG_09732</name>
    </gene>
    <organism evidence="20">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="15"/>
    <dbReference type="EMBL" id="GG697381">
        <property type="protein sequence ID" value="EFQ34588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098608.1">
        <property type="nucleotide sequence ID" value="XM_008100417.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUQ0"/>
    <dbReference type="STRING" id="645133.E3QUQ0"/>
    <dbReference type="GeneID" id="24415097"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09732"/>
    <dbReference type="eggNOG" id="ENOG502QRTW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031730_0_1_1"/>
    <dbReference type="OrthoDB" id="3238762at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF9">
        <property type="entry name" value="ENDOGLUCANASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 17" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180840" description="lytic cellulose monooxygenase (C4-dehydrogenating)" evidence="17">
        <location>
            <begin position="20"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="18">
        <location>
            <begin position="317"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="294"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="16">
        <location>
            <begin position="296"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EFQ34588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="354" mass="35351" checksum="900DD59914124A16" modified="2011-01-11" version="1">MKSIIFAVLTALAAQEAAAHATFQQLWVDGVDLISAPSLFFSLDTVVLTSRHGSQCARLPLSNSPVTNVASNDVRCNAGGTTAAKGKCAVKAGGTVTVEMHQQNGDRSCQTEAIGGAHYGPVIVYLSKVNDAASADGSSPWFKIFQDGWGAKSGAGSGDDDYWGSKDLNTCCGKMNVPISKDLANGDYLLRAEVIALHAASPSGGAQLYMTCYQITITGGTGTASPATVSFPGAYKASDPGIGINIHAKLSSYVVPGGSVASIGSTKTSGSACTGCESTCDAAKGPVGTALPVSPVGGGGGSGGGGTSPGTGSPPSCSVQKYGQCGGDGYTGCTTCVSGSTCQGVSAPYYYQCA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2011-05-31" modified="2025-04-09" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVL2</accession>
    <name>LCL2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName>Long chronological lifespan protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">LCL2</name>
        <name type="ORF">GLRG_10044</name>
    </gene>
    <organism>
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Probable component of the endoplasmic reticulum-associated degradation (ERAD) pathway.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the LCL2 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697385">
        <property type="protein sequence ID" value="EFQ34900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098920.1">
        <property type="nucleotide sequence ID" value="XM_008100729.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVL2"/>
    <dbReference type="SMR" id="E3QVL2"/>
    <dbReference type="STRING" id="645133.E3QVL2"/>
    <dbReference type="EnsemblFungi" id="EFQ34900">
        <property type="protein sequence ID" value="EFQ34900"/>
        <property type="gene ID" value="GLRG_10044"/>
    </dbReference>
    <dbReference type="GeneID" id="24415409"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10044"/>
    <dbReference type="eggNOG" id="ENOG502S416">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_142363_0_0_1"/>
    <dbReference type="OrthoDB" id="2234316at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23996">
        <property type="entry name" value="LCL2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034543">
        <property type="entry name" value="LCL2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38425">
        <property type="entry name" value="LONG CHRONOLOGICAL LIFESPAN PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38425:SF1">
        <property type="entry name" value="LONG CHRONOLOGICAL LIFESPAN PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_0000408604" description="Long chronological lifespan protein 2">
        <location>
            <begin position="21"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="120" mass="13375" checksum="585FB321BFB7E480" modified="2011-01-11" version="1" precursor="true">MRFFASLPLVILALISSAQAQFGFFDQMFGGQQQQQQQPQNVPSDPSQYQQRYDGSYCENYLCPDTLACVHFPHHCPCPWPANQDKFELTEGSSRICVSKGGFAAGEAARKVELARKGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVL6</accession>
    <name>E3QVL6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA 3'-5' helicase</fullName>
            <ecNumber evidence="7">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_10048</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="7"/>
    <dbReference type="EMBL" id="GG697385">
        <property type="protein sequence ID" value="EFQ34904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098924.1">
        <property type="nucleotide sequence ID" value="XM_008100733.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVL6"/>
    <dbReference type="STRING" id="645133.E3QVL6"/>
    <dbReference type="GeneID" id="24415413"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10048"/>
    <dbReference type="eggNOG" id="KOG0351">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001103_9_2_1"/>
    <dbReference type="OrthoDB" id="10261556at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004589">
        <property type="entry name" value="DNA_helicase_ATP-dep_RecQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00614">
        <property type="entry name" value="recQ_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710:SF120">
        <property type="entry name" value="BIFUNCTIONAL 3'-5' EXONUCLEASE_ATP-DEPENDENT HELICASE WRN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710">
        <property type="entry name" value="DNA HELICASE RECQ FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="74"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="282"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="39"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00034808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ34904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="710" mass="79159" checksum="93FC9D4B9D600F11" modified="2011-01-11" version="1">MDDDFGFDSADEADLLAVVDGVVPAMKRASDAPSNLDEPVSKRQKASDHSELSERVLKERFGLNFFRLEQRAVINRLLEGESAVVVFPTGGGKSLCYQVPAVAIKELDRETGLRSPEDSGVSVVISPLIALMKDQVDALRRRGISAAVLDSTQSREEFVETHNKLANGKLDLLYCAPERLNNEGFLASLQSIRGGIRLLAIDEAHCISEWGHSFRPDYLKIARFAKEAHVERVVCLTATATATVAEDIRATFNIPPEGLFVTSMYRPNLRLIVEPISSDEDQVEICSRFLKKNPGPAIIYVTTHAGTESLAGNLVKKKFNARPYHAGLNKDTRSEIQDKFLRSDNMIIVGTIAFGMGIDKENVRTIIHFDLPSSIEAYSQQIGRAGRDGKPSTCLLYLSNKDFFLRNIMVHGERPSRLALRALFDEICSTENCQMRAGDTFSVAMASQSRRVDIRETQLSIIYAYLELKFGLLRASTPQYSEYKYQVLQPRSVAADSSPAAEYIQRHSGKAQLWTHIDVDVPANSGSVTRADVTRKLDSWAESGVIKLDKKGVQKVFRLRKPLPSRRNGIDSIVDEIDREITKKEKQDLRRVQDLVDLLTGAACLTRGLAAYFADTTHALTTECGHCTWCETHKQVKLPDFVPQTLDEQNMRKVLNVAAKEDARFMACVAFGIKTPRISSMGLHNNKAVFETMSNCNFNDLVDTFEKMVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVX5</accession>
    <name>E3QVX5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Fungal specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_10157</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697387">
        <property type="protein sequence ID" value="EFQ35013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099033.1">
        <property type="nucleotide sequence ID" value="XM_008100842.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVX5"/>
    <dbReference type="STRING" id="645133.E3QVX5"/>
    <dbReference type="GeneID" id="24415522"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10157"/>
    <dbReference type="eggNOG" id="ENOG502QVV0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008471_0_0_1"/>
    <dbReference type="OrthoDB" id="5297881at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF4">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="7">
        <location>
            <begin position="212"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="37"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="583"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="762"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="811"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="58"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="776"/>
            <end position="785"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ35013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="830" mass="89916" checksum="3188B9D6B97E159A" modified="2011-01-11" version="1">MQSTTPILRGLSDAVPKKRGPKTDVLEALLKRVDGLEAKLKEKNAGEKTPTTPTTAGLKDEDASRSEDSPEDDPNPNPKRLALDTKIDADESAVYSPAPASEPSPPSVQPDALLDTYFTRFHSKPYHILDESSVRQRLQLNQLPNYLVHGIYAVAARYTPHPSGYQSAVHLSEEFASRSRAEIDTDEPSVDALQALLLLVIAFTAAGKGKKAYMLMTNAVGMAMALETHRELDNNARVTPVEREMRRRLFWTCYLLDRFLACGSKRPSLIGDKAILLRLPCWSPNPSVPPMDGEFFQPGSNLQFLQGSGKKSQGSTGMLIDISRILGITNRYLAAGGVKGDSHFPWHSLSNLSKIRQDLDIWASGTEDVFSSLDTLFGQPDSTILVLSKLIYHLIHCLIYRPFLPIDLAELAGTGQHQSWQIEATNMCFLHANAISELVELGKQTGTIEWPAFVGYCICTAGTVHIHGAHYNKNGGGDSTVFGMSADFLSREMQQLSELRYAWASVQHQRETLQGIYNAHAELVKSLGNNAMRHSPAFHLEDFFDRYSNIGGPGGQTFNFDAANLSLSDIVVDFTTDTYTGHDLYAPRANSMHEQERPSLKRKNTAPSGRKRPDGKVLSPLSITRMASPHGLPTPSHTRHSFSHHTPTMAAHPSPGLLATPVSLPPHPEAMEHHSIPVAHGRYDEVAANNAAVAAAAAAGFSLGHQPHHQSNMPAHPSSSFPPQFSFATPGQSGSNEGGGTYDPMFGSLPTNAFSSPAAWHGDDGGNKAAGIAAPSPGTKSNNGSTGTGPGEEKDPFLSLLEHLADNEHQITRGPGSELDFFFSGTGATQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>E3QW43</accession>
    <name>E3QW43_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">L-amino acid oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_10225</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697387">
        <property type="protein sequence ID" value="EFQ35081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099101.1">
        <property type="nucleotide sequence ID" value="XM_008100910.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QW43"/>
    <dbReference type="STRING" id="645133.E3QW43"/>
    <dbReference type="GeneID" id="24415590"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10225"/>
    <dbReference type="HOGENOM" id="CLU_2003756_0_0_1"/>
    <dbReference type="OrthoDB" id="7777654at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.660.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ35081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="124" mass="13830" checksum="25C963BF3496606D" modified="2011-01-11" version="1">MYDVVSNTTAITSMNLLKLGLPHQALLGIRELSYDRASKIAIKFKSRWWKSIYREQGGVDGISNTYLPIRNVVCPSWDAGKDAEGYVRPAVLMVSYIWAMGTLIPHSTKVPSNRDEPSCPSRAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QX46</accession>
    <name>E3QX46_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_10578</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697393">
        <property type="protein sequence ID" value="EFQ35434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099454.1">
        <property type="nucleotide sequence ID" value="XM_008101263.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QX46"/>
    <dbReference type="STRING" id="645133.E3QX46"/>
    <dbReference type="GeneID" id="24415943"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10578"/>
    <dbReference type="eggNOG" id="KOG0028">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061288_18_1_1"/>
    <dbReference type="OrthoDB" id="343296at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050145">
        <property type="entry name" value="Centrin_CML-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23050">
        <property type="entry name" value="CALCIUM BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="109"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="145"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ35434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="181" mass="20204" checksum="5376FDE07EE9C02A" modified="2011-01-11" version="1">MSSPSALFDLNQGRRDLASLPADWQQNIREAWEVVDQQGLGSLNAREWPFALRAIGFDLARTETYALLLAHGVPPHDHDPSRGPCSPSRLRMPQEHFSAIAAWLLVRRDPQEEAEDAWKMFDPRGTGRITLDSLRAVCAEVNSTLSEADMRRMIDMADISGKGWVTKDEFIEVAKGGFGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXL1</accession>
    <name>E3QXL1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_10743</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697396">
        <property type="protein sequence ID" value="EFQ35599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099619.1">
        <property type="nucleotide sequence ID" value="XM_008101428.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXL1"/>
    <dbReference type="GeneID" id="24416108"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10743"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_25_2_1"/>
    <dbReference type="OrthoDB" id="4139357at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010573">
        <property type="entry name" value="MFS_Str1/Tri12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF195">
        <property type="entry name" value="PEP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06609">
        <property type="entry name" value="TRI12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="243"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="313"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="346"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="381"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="406"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="536"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="45"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ35599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="610" mass="66092" checksum="D8BC868A6A58DB4A" modified="2011-01-11" version="1">MVRDREMKIRMAQEAQAVIEFEEDPHRAALEDNPSEVRVSIKTWIAIFSMALSFGPPVGLAFLAVASVVVQITNELDGQDQLAWVIGSWSLSTACSFSLAGPLSDVFGRRMLVLGGQFVVGLGCIAAATTHDISTLIAAETLIGLGTGFVFVSYAGVPEMLPNKWRTLGLGILEAGIAVPWGILSVLLGNALFKYASWRWIFGIATIIEFISLTGTGFSYYPTPRPRGDFDKTRTQQLKDIDWVGLLLFTSGLATALIGLTWGGTSTHPWNSAGTIAPIVVGFAVLALGFFYDFKVAAHPIFPLKLFIMFRRFSVLLIVMFVSGMNFYAMSALLPQGFLYMFTTDGIRIGVLSLPNTLMIGFTGVLAPLIAHKVGYIKWQLVIGMALQAIFIAASAATVYPNMKLAYAFVPAIGVPMFVWVTILSYSIASLHVPHSNLGVAVGLIGTFRSAGGAVGNAIFNTIFQEKFRKFAADMVANAAISNGLNPADLDLIIPAAIEFDTGNPRALLNVPGITPEIQEALKTAVRAGAGHAFKIVFYGTIPFSIVALLCTFLVEDPTAYMTNHIQSGMDDQAISKRVRRFTQPEEGHVIEFETRKFQVGPAGKIWQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXN8</accession>
    <name>E3QXN8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10785</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697397">
        <property type="protein sequence ID" value="EFQ35641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099661.1">
        <property type="nucleotide sequence ID" value="XM_008101470.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXN8"/>
    <dbReference type="GeneID" id="24416150"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10785"/>
    <dbReference type="eggNOG" id="ENOG502T2FU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1337418_0_0_1"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="160"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="205" mass="23327" checksum="84B2835BD18CF6FC" modified="2011-01-11" version="1">MEREEFPPQRPASSNVFSTTTPVSTSSNGRRRGSTAQYEDTDEDCLEARLERILKIVEDNGFDSIDSMTSTYYRSELSEDSFLRPMQATSRTRRLRSLLSDLHASHKSWTGREKSAYAEEIVRSAESICSDELETLYGSRAPHTSPVRRRASSTLREPSLQDQQSASLQSRRREIARRIREVLSSLDISEFLQKDQAALQNSTRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXR3</accession>
    <name>E3QXR3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Arid/bright DNA binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_10810</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697397">
        <property type="protein sequence ID" value="EFQ35666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099686.1">
        <property type="nucleotide sequence ID" value="XM_008101495.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXR3"/>
    <dbReference type="STRING" id="645133.E3QXR3"/>
    <dbReference type="GeneID" id="24416175"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10810"/>
    <dbReference type="eggNOG" id="KOG2744">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008900_0_0_1"/>
    <dbReference type="OrthoDB" id="1938591at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016514">
        <property type="term" value="C:SWI/SNF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16871">
        <property type="entry name" value="ARID_Swi1p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.60">
        <property type="entry name" value="ARID DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051232">
        <property type="entry name" value="ARID/SWI1_ChromRemod"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001606">
        <property type="entry name" value="ARID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036431">
        <property type="entry name" value="ARID_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13964:SF27">
        <property type="entry name" value="HAT-TRICK, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13964">
        <property type="entry name" value="RBP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01388">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01014">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00501">
        <property type="entry name" value="BRIGHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46774">
        <property type="entry name" value="ARID-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51011">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="ARID" evidence="6">
        <location>
            <begin position="366"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="342"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="462"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="707"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="43"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="128"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="187"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="205"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="229"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="241"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="342"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="468"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="497"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="523"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="546"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ35666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1100" mass="120629" checksum="DC1C91CA6FB1EE66" modified="2011-01-11" version="1">MSTWMNESAVPNHNGNAFPHMNDPNAAGAMMDPSAFMGNPAHFNPAQFANPQQAQQAQQQQQQQQMAAMQNGQMRNASPSSFQNPAYQTNPVIPSKRPRPREDSLAGSPRQNPGMLPTSRSETPQTFPGYQPAGMPQQPQGQPSPYPHLQPNGSANATPSPIMANQLRPGSVPQRVATASPHPFSPGAQQFAPQASPNPSEHGTPQPNHYMQQQQNMQNMPQGYNPNFNPSPSPARPSPNPNAMAASGMMPQQMPQQMGQMPQHMGQMPNQMLPPNMQPRNPMEQQQMAAYQARLAKQLQQGTMQGMQNMQNMQMQNMQMAAQMQAQNMPQGRGMMPKQPMPMPNGQMPPGAMRPQPQQPQRPMPGSNPESFMKSLNNFMAAKGQQLDPNPAIGNRPVNLLTLFQSVQSKGGYKPTTAGNQWPNVSNSIGFHPGQIPQAPQMLKEIYERNLLRFEEAWAAQQNRQRMMQHPNQPGMPGQPGQPMPPGAQSQSTPTKQMSPQAQMPPQQQMMPQGPPNMPPQVQTPVKQGSFSGPSPSVNGFQTPQAPGPHTPGPGPQGHARNSLSRSVEPTPGHPQGFPSASPASVKGGGMHPMTAPPGMEQNPMAASIKPRMLRLAHESDEYTPSARPLETYGGINVRAFDLKGLELQGLKPDVPPPYELGYVDLHALTRSLESGIHGEVRLALDTLAAVTATQHQALHIHLKYCEELIEALLECAEEQLDLLVENTEEASADIQLTPYEDIARACWVDKMGVKELPKFGSLEYELDRAVERFSCVITILRNLSFPEAVNDNHLVLGDELVIKFLCAVIRYLGTRSMLFRTNANTLEFMKDAVILLSNIAGAVEIPGREQALCLLHFLLAFAPAPGPTCVDDKLYFPPYQPGVHTYTFHAVDALARFLARDQPNRTHYKMLFLMDASSSPPYDLLTRSFALATTVVPIQSPESAVAHIEAPERFFRLVEDRKPWLMQGLLAADILASLAPGYETGVARSWLSSGNGFARALYHFVQVLEAQFEQPWQTRSGQGDPAGRDTGLVYIATSGISTLRRLAEKARDPNDPKSSVPADSLPSEESLFKMMLMRSPEWTKDGVIKNLVAYASADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QY19</accession>
    <name>E3QY19_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10912</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697399">
        <property type="protein sequence ID" value="EFQ35757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099777.1">
        <property type="nucleotide sequence ID" value="XM_008101586.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QY19"/>
    <dbReference type="STRING" id="645133.E3QY19"/>
    <dbReference type="GeneID" id="24416277"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10912"/>
    <dbReference type="eggNOG" id="ENOG502SI27">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019838_0_0_1"/>
    <dbReference type="OrthoDB" id="3522351at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021840">
        <property type="entry name" value="DUF3433"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37544:SF3">
        <property type="entry name" value="SPRAY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37544">
        <property type="entry name" value="SPRAY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11915">
        <property type="entry name" value="DUF3433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="470"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="580" mass="63781" checksum="7B8976444F30D1B3" modified="2011-01-11" version="1">MSGKSKGSPSRPYSWLATNSLQWPSLLGFVVLDFAFAITTVALTIASSQKNGFVTVSTLNITVTDREATTFNISSDLGLLWTSLPSLIFSLFGAYWTWIAGAIAERQPYVELRKDGGSEARMSVIVDYRFINSLWRWWKAFRKSHFTVGSTGLLSVFLTYLVAPLAAHLFVAQTMAVSVPTPIIYAKDYNADNINAALDWRPVLDTVSATLLYGGNNIPWTDTERAFRPFAVNSSSCVKSDMAANTTSYSAYLSCELVNDYTIASSGDIVTVSGNDRGCDFQQSFPVVNTQEIYLKTTVDFDSSAEAHYSRLVFTAARYSESASDNIDNIDNISVISCATGYRQASGTCRVTQSKGSSAVVSFAEVGQPDISRPKLWMVFEQGTLGPVLTFNLQAKWTTSDMSNLVLYYAQRAQGSNSLAPEALLEASPKVFTAIYMNAVVIHGFDSPQNVEMAAGTVFIPTTRLFVVCWVAYIIIAFLAVALCTVIFLFFRLRDAPSILTEEPRGLLSMAAILGGSQLLVIASDTRQETGFDGEIRKRGKARSDVKDRKWRAAMNPETGHWVVRTVRNDEGELTEHLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QY58</accession>
    <name>E3QY58_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">EXS family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_10991</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SYG1 (TC 2.A.94) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697400">
        <property type="protein sequence ID" value="EFQ35796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099816.1">
        <property type="nucleotide sequence ID" value="XM_008101625.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QY58"/>
    <dbReference type="STRING" id="645133.E3QY58"/>
    <dbReference type="GeneID" id="24416356"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10991"/>
    <dbReference type="eggNOG" id="KOG1162">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006116_1_0_1"/>
    <dbReference type="OrthoDB" id="9970435at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000822">
        <property type="term" value="F:inositol hexakisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016036">
        <property type="term" value="P:cellular response to phosphate starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14475">
        <property type="entry name" value="SPX_SYG1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004342">
        <property type="entry name" value="EXS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10783:SF103">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 53 MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10783">
        <property type="entry name" value="XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03124">
        <property type="entry name" value="EXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51380">
        <property type="entry name" value="EXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="496"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="542"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="583"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="614"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="759"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="806"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="domain" description="SPX" evidence="10">
        <location>
            <begin position="1"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="EXS" evidence="9">
        <location>
            <begin position="693"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="67"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="907"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="963"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="284"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="162"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="912"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="964"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="985"/>
            <end position="1015"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ35796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1037" mass="117929" checksum="F892435D9415E878" modified="2011-01-11" version="1">MKFAKELEQDLVPEWRIKYLNYKAGKKHVKAVSRAINRANGSPLNNASGPENQNGTASYLFHAHSPFRSHRHTRSKASNAPDERTSLRGTPAPVGSAHQKPAHPIPTPASHNDRQGWNDGPSDLRYGSFVHTPPQHETGSPLDRRQTFELPGPAMHAPSPHSGPSPQAASTQAVSTARQALHRSATVDESVPGPVGTPATEHERTPSSLRLPHPATIGPGPNASPRGGLRRLFSGASHLGRVGTNSEYGLQPSALDMVRQKEKEFFEFLDSELEKVEEFYKMKEDQAGERLALLKEQLHEMRNRRIQEINAQKRQAEMEFLSRGDGDRDAAQRGPLGWIDPVKTKIFRPGPNSRALSKMAHTPVMRPAEGGDATRDYIRRPHEHDVPYRTAKRKLKLAMQEFYRGLELLKSYALLNRTAFRKLNKKYDKAVKARPQYRYMNEKVNKSWFVNSEVVDGHIKAVEDLYARYFERGNHKIAAGKLRSLSRRPGDESGSAFRCGILLGTGLVFAIQGTVFGGQLLFDDDAEVRARTGYLMQIYGGYFLMLLLFSMFCVNCAIWTRNKINYPFIFEFDTRTNLDWRQLAEFPSLFTFIFGVFIWLNFSEYGTNEVYEYYPVVLIALSAAIIFMPAPILMARSRKWFAYAHWRLLLAGLYPVEFRDFFLGDMYCSLSYAMCNIELFFCLYANAWDNPTQCNSNHSRLLGFLGALPPIWRFLQCLRRYRDTRNIFPHLVNGGKYTMSILAAMSLSMYRIDNTHGNLAMFVTFATINAVYTSIWDLFMDFSLLQPHSRLWLLRDITGLKKRWPYYFIMVTDPILRFSWIFYAIFTHDTQHSSIVSFLVALAEVARRGMWTLLRVENEHCANVAQYKASRDVPLPYPVEPRVSQRFPGVAEEGSGKDDDVAETTGEARLDSGAAGASGTTTARPTTDQRMAEEGTVRRRRRSGILPLQRSFSKIIAEGAQAGFRKEEEAGRRRRGEARGGWRHGERRRRRRRRRRRRRPRGALGRVGRRRRRGGFHGDPRGAEAGARARGRESASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYM8</accession>
    <name>E3QYM8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">lytic cellulose monooxygenase (C4-dehydrogenating)</fullName>
            <ecNumber evidence="15">1.14.99.56</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">GLRG_11110</name>
    </gene>
    <organism evidence="20">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="15"/>
    <dbReference type="EMBL" id="GG697405">
        <property type="protein sequence ID" value="EFQ35966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099986.1">
        <property type="nucleotide sequence ID" value="XM_008101795.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYM8"/>
    <dbReference type="STRING" id="645133.E3QYM8"/>
    <dbReference type="GeneID" id="24416475"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11110"/>
    <dbReference type="eggNOG" id="ENOG502QVRD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031730_1_1_1"/>
    <dbReference type="OrthoDB" id="4849160at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF6">
        <property type="entry name" value="ENDOGLUCANASE IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="19" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 17" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180950" description="lytic cellulose monooxygenase (C4-dehydrogenating)" evidence="17">
        <location>
            <begin position="18"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="18">
        <location>
            <begin position="18"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="248"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="252"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="290"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="314"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="341"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="363"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="386"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="408"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EFQ35966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="450" mass="45871" checksum="0F19D220E34C1695" modified="2011-01-11" version="1">MKSTVTSLLGSAALVAAHGIVNNAVIGGKNFTFYQPYQDPYMKPAPERISRAIQSNGPVEDVTSIDIQCGAATAGSGTIPAKLVAKAAAGEEVTLDWTIWPDSHIGPTITYMAKCADNDCTTWQPGNDAAWFKIQEQGREGTSNNWGATPLMKAGNSGVKYTIPECIAPGQYLVRHEIIALHAASSYPGAQFYPSCHQIEVTGSGSTNPSDLVAFPGAYKGTDAGITYDAYKAQPYTVPGPKVFSCAGSGSGSAPASSAAPASSAPAATTAPATPSQTAVADDNDEDCPATTTAAAPVATSTQPGGDEEDDCPAETPSATSSTAASSPTAKEVDAEDDCPAETTAPVATPTAAAGDDEDDCPAESPSAATPTSTQSANDDEDDCPAETPSATPTPTQSANDDEDDCPAESTAPVATPTAAAGDDEEDCPAETPSATPRAKRMTIHERRLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZS3</accession>
    <name>E3QZS3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Alternative oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_11506</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697420">
        <property type="protein sequence ID" value="EFQ36361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100381.1">
        <property type="nucleotide sequence ID" value="XM_008102190.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZS3"/>
    <dbReference type="GeneID" id="24416870"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11506"/>
    <dbReference type="eggNOG" id="ENOG502TB52">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105917_0_0_1"/>
    <dbReference type="OrthoDB" id="20368at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006004">
        <property type="term" value="P:fucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11296">
        <property type="entry name" value="O-FucT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019378">
        <property type="entry name" value="GDP-Fuc_O-FucTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10250">
        <property type="entry name" value="O-FucT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0294">Fucose metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ36361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="257" mass="29100" checksum="6744CD1D02F46B52" modified="2011-01-11" version="1">MFGWPVGYDPPFMVRHFSGLVRPRDEIKLLAAAALQRMQDQYNAHVDFRTSEDPRVRDNAFIGVHLRVEKDATDYHYLSYEDQLAYLKRRLRGRNGNATHPPDMTLPDTEKSVLYVACGDTDSIARLAKDVAPITVVTKNDLLPEDTFAGASLRNMTWDQQALVDMLILEHSGYFIGVRESTFSWHLALQRAAAVNWVTGGYPGNCWLNSSDIDSANIRSGCKFMLQDNEEWRDDLSAVVSNGHQWGGPHMEISVWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0D9</accession>
    <name>E3R0D9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Infection structure specific protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11710</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697440">
        <property type="protein sequence ID" value="EFQ36577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100597.1">
        <property type="nucleotide sequence ID" value="XM_008102406.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0D9"/>
    <dbReference type="STRING" id="645133.E3R0D9"/>
    <dbReference type="GeneID" id="24417074"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11710"/>
    <dbReference type="eggNOG" id="ENOG502R9VB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091752_1_0_1"/>
    <dbReference type="OrthoDB" id="4845881at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180992" description="Infection structure specific protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="208" mass="20258" checksum="E6E417B2DE925DE2" modified="2011-01-11" version="1">MQSKILLVAAGAATGALAIGDLSGSFPQNLRRGAAALEARDEASCIAAVSEHATVTADFPPIPDALATGAGANIPQVTDPCQFPSVTGSIGEVLTSYSSALQSWEDAHITEIRALWGACSDVPEISALIAQFGASICSTALGHITSQASGVATATATATATATATTAGAGETSAVPSTAVPAAAAPRETGMLVAAAAAAAGFFGAAML</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0E5</accession>
    <name>E3R0E5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11716</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697440">
        <property type="protein sequence ID" value="EFQ36583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100603.1">
        <property type="nucleotide sequence ID" value="XM_008102412.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0E5"/>
    <dbReference type="GeneID" id="24417080"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11716"/>
    <dbReference type="eggNOG" id="ENOG502S4V1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065416_0_0_1"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="1">
        <location>
            <begin position="63"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="303" mass="33675" checksum="64817F3ACCAA08E7" modified="2011-01-11" version="1">MTTKNTHPDGPKVPIFRAMDKTIGSHWEETMIDTSRTILGPLNARLVSQMGLGAETHEPIAFLDSACGAGPATQELYKAVPRQVFQKSEIVCGDESPMMVDLVKKRIKNEQWAGAQGRVIDATDSGLESDSFTHVVISLGLHVIPRPDTVIKDVVRILRPGGVFGCVTPHADHTSWVVDMRTAFASLPFEAPFPEKNWSQVHKVGRWYDEAWVRTYLLENGFCAVEVRVERGTMPIRNAKHWLDIFGPATAYLLNIEWSEELRAAHGLEEVKALIGQHLEDKYGGKGWEMGYACIVASGVVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0S3</accession>
    <name>E3R0S3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Kelch domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_11861</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697480">
        <property type="protein sequence ID" value="EFQ36711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100731.1">
        <property type="nucleotide sequence ID" value="XM_008102540.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0S3"/>
    <dbReference type="STRING" id="645133.E3R0S3"/>
    <dbReference type="GeneID" id="24417224"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11861"/>
    <dbReference type="eggNOG" id="KOG4441">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004253_10_0_1"/>
    <dbReference type="OrthoDB" id="45365at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46344:SF27">
        <property type="entry name" value="KELCH REPEAT SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46344">
        <property type="entry name" value="OS02G0202900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01344">
        <property type="entry name" value="Kelch_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179039" evidence="3">
        <location>
            <begin position="22"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ36711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="338" mass="35854" checksum="323720E6697AC66C" modified="2011-01-11" version="1">MNTKFLTPLLPLLFLSRHVLSLPSNSDSWHLLPPIPLGPQQEESVAAIGGDIYIVGGINLVPPNATTIPSVSYMQVYSTTTNTWRRVADIPMAVNHANMASLNGKLYVLGAIAGSGVNYPIANSFAYTPATDTWDALPPMPAGTERGAAGVGVWGDNIVIAGGLNYTDFLNGAQTTVPWTSMFNTRTLQWDTAFPDLPDGGRDHCGGVVLGDTFYVVGGRVSGERNVRGTVWAMDLGNATRTWVEMEGKMPTPRGSHSTALVDGKIYTFGGEGNPVGNGIFNNVEVYDVKADSWEVLAPMPEPRHGTAAAVVDGRVYIPGGAYKGGAGAVDSNQMFIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3R129</accession>
    <name>E3R129_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_11963</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697573">
        <property type="protein sequence ID" value="EFQ36817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100837.1">
        <property type="nucleotide sequence ID" value="XM_008102646.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R129"/>
    <dbReference type="STRING" id="645133.E3R129"/>
    <dbReference type="GeneID" id="24417326"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11963"/>
    <dbReference type="HOGENOM" id="CLU_1077731_0_0_1"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ36817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="258" mass="29056" checksum="7183E2CD04691BBF" modified="2011-01-11" version="1">MLFTQALGADLFLFNNPRIRRILEFGTATGILAIDAADRKGDEATIVSVDPCQAHPESYPSNIVFCQAQADVLRGFSPNHFDVVRISDRPGLQFDTNRLYAEAYSLLRPRGQVEVIHLEIAPGFTGRSPPDDSKLAYWCYRFQLALEELGAPQLLVGDTANQLRAAGFIQVTTEKIRLPTCWPPDDTETYELGRWLNLFLRRFVESMTPLVFGQLLGWERERFASLVDEVSIEMSTLTVGAYMDLYFWKGIKGPTGPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3R155</accession>
    <name>E3R155_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_11990</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697621">
        <property type="protein sequence ID" value="EFQ36843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100863.1">
        <property type="nucleotide sequence ID" value="XM_008102672.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R155"/>
    <dbReference type="STRING" id="645133.E3R155"/>
    <dbReference type="GeneID" id="24417353"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11990"/>
    <dbReference type="eggNOG" id="KOG0504">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000134_45_5_1"/>
    <dbReference type="OrthoDB" id="4851774at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="64"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="97"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ36843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="137" mass="14386" checksum="300BADF36E6BC701" modified="2011-01-11" version="1">MSVELHGPPARVGQASENSDYNANDADPQAFQTVLHIAAIAGHNAMVDMLLVNGRLDVDVRNSEGNTALHVAVSNQQLVTVLRLLSHGADPNAENAAGWTPLHTAVQMGSVDAVGALVAHGGNVRKKAPMRNVDLIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q206</accession>
    <name>E3Q206_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nucleotide sugar dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_00251</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089127.1">
        <property type="nucleotide sequence ID" value="XM_008090936.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q206"/>
    <dbReference type="STRING" id="645133.E3Q206"/>
    <dbReference type="GeneID" id="24405616"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00251"/>
    <dbReference type="eggNOG" id="ENOG502QQVE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023810_0_1_1"/>
    <dbReference type="OrthoDB" id="5059218at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017476">
        <property type="entry name" value="UDP-Glc/GDP-Man"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036220">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014026">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001732">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028359">
        <property type="entry name" value="UDP_ManNAc/GlcNAc_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03026">
        <property type="entry name" value="NDP-sugDHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43491">
        <property type="entry name" value="UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43491:SF2">
        <property type="entry name" value="UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00984">
        <property type="entry name" value="UDPG_MGDP_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03721">
        <property type="entry name" value="UDPG_MGDP_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500136">
        <property type="entry name" value="UDP_ManNAc_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000124">
        <property type="entry name" value="UDPglc_GDPman_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52413">
        <property type="entry name" value="UDP-glucose/GDP-mannose dehydrogenase C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDP-glucose/GDP-mannose dehydrogenase N-terminal" evidence="4">
        <location>
            <begin position="81"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="UDP-glucose/GDP-mannose dehydrogenase dimerisation" evidence="3">
        <location>
            <begin position="258"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR000124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ25107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="469" mass="50871" checksum="25040349AF85834F" modified="2011-01-11" version="1">MKITIDKPFTHSRSLSVPVPETPPLEALGLGLPGFDSFKSTMELPLTPVTPPPEYIEHSFLHNDKTIDVSPTVDPNDQPLVAVIGVGYVGTHLVESFSAHYNVLGFDVSERRINEIRKELPSERIRFTTCKTDLREATHFLISVPTLLKVDKSIDTSYLQSAIATVAQHARPGSTVVVESSVAVGMTRSLLGPVALSRGFYAGMSPERVDPGRTEPPCHAIPKIVSGLDDSIPGSLASIMRLYGQVFDRLVPVSRTEVAEMMKLYENCQRMMCIAFANEMADACIPHGIDPYEVAAAASSKPFGYMPYTPSLGVGGHCIPVNPYYLLSNSDFPLLGAAAEKMAARPAAIARRAIASLAKDAKTGAAPALVRPRVLVVGVGFKAGQSVLSNSPGVDLVHEFVRSGEVDVMFADPLVKQNAVPAAPRLADEKWNRETLETFDMIIVSFRQHGMDFGVLEDLRGVKVEMWCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q215</accession>
    <name>E3Q215_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">lytic cellulose monooxygenase (C4-dehydrogenating)</fullName>
            <ecNumber evidence="11">1.14.99.56</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">GLRG_00260</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="11"/>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089136.1">
        <property type="nucleotide sequence ID" value="XM_008090945.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q215"/>
    <dbReference type="GeneID" id="24405625"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00260"/>
    <dbReference type="eggNOG" id="ENOG502SING">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031730_4_0_1"/>
    <dbReference type="OrthoDB" id="3496539at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF2">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 13" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179304" description="lytic cellulose monooxygenase (C4-dehydrogenating)" evidence="13">
        <location>
            <begin position="20"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="14">
        <location>
            <begin position="20"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="228"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="262"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00045077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EFQ25116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="319" mass="33189" checksum="6B5D2AEED3BA23AD" modified="2011-01-11" version="1">MKATFVLSAVLGLASSASAHYTFDKLLVNGQQQGGDNTYIRKHQNSYMPTKFKNTPSGSITPNDADFACNKGATPAAKVMTVKAGDKVALKQAFGGTGMQHPGPSQFYMAPVSNAATAATSGLEWYKVHQSLLCKSGSAEDLRHGLWCSYGEDNVNFLIPDSIPNGQYLVRGEHIGLHGAHVGEAEFYYACAQVEVTGNTATSMPGTGVKIPGVYKQDDAPINFSIWGNSNSYKQGPGPDVIPGGTIRGSPDGSSGDKIARVAGGSTGSSAATQPSASQPAASQPAVSKPAPSTPAASQPTPSKAASSKPACRRRRRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q282</accession>
    <name>E3Q282_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00327</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089203.1">
        <property type="nucleotide sequence ID" value="XM_008091012.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q282"/>
    <dbReference type="GeneID" id="24405692"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00327"/>
    <dbReference type="eggNOG" id="ENOG502T6H9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_980097_0_0_1"/>
    <dbReference type="OrthoDB" id="4843340at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="282" mass="32769" checksum="2712DD6AAC4B58DE" modified="2011-01-11" version="1">MAGKHRLPTGLSDIPFSPVHKKRRIVKQSNPWDDVDDAQGAQGSQPKTFTKDDADALYHQVEDFEKDYRKESCRVYTDTPPREVELRITRVTLYRRSRSIRHLLHRTFFPDASLILRPSAEAYHTLTAHRAALTRHQALWHHRRARRRTLRASRALALRTATFVAAEAAHDADAEHDPNDPRDPSRHRVAFAQRRRWYRTVKRDMRRRGQWVSRAAPGPGVEWEPFDVHGDPGARVSFFEPVAGDWILPAHVRDARDLDVFLNQLGLRFTPVEIPLRDRPWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2Q7</accession>
    <name>E3Q2Q7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_00030</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ24886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008088906.1">
        <property type="nucleotide sequence ID" value="XM_008090715.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2Q7"/>
    <dbReference type="STRING" id="645133.E3Q2Q7"/>
    <dbReference type="GeneID" id="24405395"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00030"/>
    <dbReference type="eggNOG" id="KOG2504">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_1_2_1"/>
    <dbReference type="OrthoDB" id="2213137at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF287">
        <property type="entry name" value="MFS MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="103"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="135"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="164"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="194"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="351"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="391"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="17"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ24886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="417" mass="44720" checksum="DE4F9AA5775159CF" modified="2011-01-11" version="1">MSSQTELQYLTPRTAQVPISAPPLRGPHSAAESGTGTISGVRDSHDEGQEFPSLPPVDGGRQAWLFLAACFAIEMLVWGFPFAFGVFQNHYSTNPPFAGQPNIAVIGTCAMGIMYLSGPVVIGLLRLFPRESRHAPILGLVVMCVALAASSFSRTVTHLIVTQGVFYGIGGAVAYCPCILYIDEWFVRRKGFAYGIMWSGTGLAGVVLPLLMEYLLGHVGFRTTLRLWSGLLFALTAPLAFFIKPRLPVSQATHARPFSNLRFMLCRPFALYQVASIVEALGFFLPGIYLPSAGATAGTFLAWGFSSNLGVLYVFCVVYGLFAGAYTSAWPGIMKAVVEHERERERGVDPSMVFGMLAAGRGVGNVISGPLSEALIKGAPWKGEAGFGYGSGYGTLIVFTGVTALMGGASFAWKRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q316</accession>
    <name>E3Q316_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ig-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00139</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ24995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089015.1">
        <property type="nucleotide sequence ID" value="XM_008090824.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q316"/>
    <dbReference type="GeneID" id="24405504"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00139"/>
    <dbReference type="eggNOG" id="ENOG502T4B5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1111310_0_0_1"/>
    <dbReference type="OrthoDB" id="4837799at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180158" description="Ig-like domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ24995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="250" mass="26603" checksum="9C7944D7E85A33AC" modified="2011-01-11" version="1">MRGSVSALIIFAIIPVGLGAVVAAVAFKGKNVEPHAASSSSVTTAIIKMTDTPTTTPGVLERNSLWTINTAKPQSIVINISTDRPTTTAAVDGSLTIKCDHEWHQDSTPMCTYGPGFARRDSVKVHIPNDPITSLGNPPGPILMGDRQDLETLDKKQYVASVAMAASASASIDCKYKYCDGQTQYCMYWAGVTGWNPSLGPVPGMTRTALSGCQVPATEFTTYRSVHTTMAPTKNRVCSTKTSSFRALAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3G1</accession>
    <name>E3Q3G1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">L-arabinitol 4-dehydrogenase</fullName>
            <ecNumber evidence="10">1.1.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">GLRG_00707</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-arabinitol + NAD(+) = L-xylulose + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16381"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17399"/>
            <dbReference type="ChEBI" id="CHEBI:18403"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="9">Carbohydrate degradation; L-arabinose degradation via L-arabinitol; D-xylulose 5-phosphate from L-arabinose (fungal route): step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.12" evidence="10"/>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089583.1">
        <property type="nucleotide sequence ID" value="XM_008091392.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3G1"/>
    <dbReference type="STRING" id="645133.E3Q3G1"/>
    <dbReference type="GeneID" id="24406072"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00707"/>
    <dbReference type="eggNOG" id="KOG0024">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_11_5_1"/>
    <dbReference type="OrthoDB" id="2148442at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050019">
        <property type="term" value="F:L-arabinitol 4-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003939">
        <property type="term" value="F:L-iditol 2-dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019568">
        <property type="term" value="P:arabinose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006062">
        <property type="term" value="P:sorbitol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05285">
        <property type="entry name" value="sorbitol_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000068">
        <property type="entry name" value="Sorbitol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045306">
        <property type="entry name" value="SDH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161:SF12">
        <property type="entry name" value="L-ARABINITOL 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161">
        <property type="entry name" value="SORBITOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0054">Arabinose catabolism</keyword>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="14">
        <location>
            <begin position="45"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="13">
        <location>
            <begin position="195"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00039783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EFQ25563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="368" mass="39191" checksum="1E45BE7F5D3E9588" modified="2011-01-11" version="1">MSATVGSVKPSKANIGVFTNPAHDLWINEAEPKLEAVQAGEGLKHGEVTVAIRSTGICGSDVHFWKHGCIGPMIVDGDHILGHESAGEILAVHPSVTHLKVGDRVAVEPNVICNACEPCLTGRYNGCEQVQFLSTPPVPGLLRRYVNHPAVWCHKIGNMSYENGAMLEPLSVALAGMQRAGVRLGDPVLVCGAGPIGLITLLCAKAAGACPLVITDIDDGRLAFAKELVPTAITHKVGRGTAEEEAKRIVESFGGIEPAVAMECTGVESSIASAVWASKFGGKVFIIGVGRNEINFPFMRASVREVDIQLQYRYCNTWPRAIRLVESGVVDLSKLVTHKFTLEDALGAFEAARDPKSGAIKVMIQSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3I8</accession>
    <name>E3Q3I8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein phosphatase 4 core regulatory subunit R2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00734</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PPP4R2 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089610.1">
        <property type="nucleotide sequence ID" value="XM_008091419.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3I8"/>
    <dbReference type="STRING" id="645133.E3Q3I8"/>
    <dbReference type="GeneID" id="24406099"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00734"/>
    <dbReference type="eggNOG" id="ENOG502SBSZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024587_1_0_1"/>
    <dbReference type="OrthoDB" id="341898at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030289">
        <property type="term" value="C:protein phosphatase 4 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015267">
        <property type="entry name" value="PPP4R2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16487">
        <property type="entry name" value="PPP4R2-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16487:SF0">
        <property type="entry name" value="PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="43"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="242"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="327"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="411"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="336"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="385"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="430"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="510"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="524"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ25590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="535" mass="55480" checksum="17F4D68517F6F3E7" modified="2011-01-11" version="1">MEIEVDEDLLRTVATGGQMDYGLWPALSQGIISRLDKIAHNEFPIPNLPTPPQPINASGQQPRLLSPLPSSSIEPASSLPSSQDADKENSKSNVPLSSTIPVESEAANTAAAAPGSLPAQIVSMLEEINSVLSTFPKYPPHTIQRLAELVLEPRRHYRHLASYLHAVDRVVHVTSGANTYPLPPAIPDMSTMTLLSNGGANDQENPAAAVAWSNSTNSVASTVGTDEALGGALLTPIPWLTRRVSPGSSSPGSSNGGGPAEIRTESTETIDGPNGVGSIETVSVSVNGIPSMGASNSNRAITQGELLRQEQEQGVVPVNQLVRQAEEAQHAAALRSGDDGRAASPERQDQEQQGREQNTGAAEEENEVPHARGPEEIGVGDLGPQSETTSFTSGGPSLEMQGIDVEAAVGRKAEQTHATPSLEDAEKENTAAAATGEEGSAEAAVDDAASDMSVTSHPKRDADEELDGLASKKVKEHEGDVAGGAPEAATADSSGKGGVEEEEEGKAVKNEIVTTGAETAAAEPETKTEDTAADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4I4</accession>
    <name>E3Q4I4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Calpain catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_01143</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090019.1">
        <property type="nucleotide sequence ID" value="XM_008091828.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4I4"/>
    <dbReference type="STRING" id="645133.E3Q4I4"/>
    <dbReference type="GeneID" id="24406508"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01143"/>
    <dbReference type="eggNOG" id="ENOG502T5YR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039414_0_0_1"/>
    <dbReference type="OrthoDB" id="424753at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004198">
        <property type="term" value="F:calcium-dependent cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022684">
        <property type="entry name" value="Calpain_cysteine_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001300">
        <property type="entry name" value="Peptidase_C2_calpain_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183">
        <property type="entry name" value="CALPAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183:SF379">
        <property type="entry name" value="CALPAIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00648">
        <property type="entry name" value="Peptidase_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50203">
        <property type="entry name" value="CALPAIN_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Calpain catalytic" evidence="8">
        <location>
            <begin position="260"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="47"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="438"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR622684-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ25999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="513" mass="58429" checksum="4EC23293103A021A" modified="2011-01-11" version="1">MGDIRTTERDSNVIALVEAILGHKIESQPGSSTQSTMEDYEDLVDMNNDHDFSKEPRPDSPPRNPCVGAVNPYALAEALIGRKIDRQSMTAAKILQNVLQTDYDELFDMRHHSVLFAGMKLNEKERRAEMYDEKDMKILNERDLMTPDFSGVRRLEDLEKVGLKDLKDAKVKLARMQNGKLRLVLHAHELGKTVSNRDVTMSINELVTPFRMERGHWQPPNASWRDMYDYFFQTVNKRLITDITEFRIGERRETRHQFDDPTQGCTSNSWFIAALFSVFWSDPGAINRATRVHHNEKKRFLSVKFHDKGGKQNNKTQTVEVNYEIPINNSDNEPLYCRSSDGADIWPSLYEKAFAKWITGSNSEQPDITQTHCGDPVKAMAQINGRTPHYYHCDNHSAQTLLGLVRSNSVNNKTINPMTAYTYATGREYHGANIVANHAYSVLGYCVLGDKQYIVLRNPWGVTEPQGLTSYTGLLGRLEREVWNPATLLDHGGLFALEAESFKRCFSCIGVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4L7</accession>
    <name>E3Q4L7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_01176</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ26032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090052.1">
        <property type="nucleotide sequence ID" value="XM_008091861.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4L7"/>
    <dbReference type="STRING" id="645133.E3Q4L7"/>
    <dbReference type="GeneID" id="24406541"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01176"/>
    <dbReference type="HOGENOM" id="CLU_2542437_0_0_1"/>
    <dbReference type="OrthoDB" id="5343383at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ26032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="83" mass="9799" checksum="E53A245FE80F7DD2" modified="2011-01-11" version="1">MVPLPRPDTEVAEYYPEIWGAIRMGEEEEYELADPGIEDARNIYREHGWPDLARFRRQECYDALVDFRTKVMEEDEEDGYGPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q561</accession>
    <name>E3Q561_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_00972</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089848.1">
        <property type="nucleotide sequence ID" value="XM_008091657.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q561"/>
    <dbReference type="GeneID" id="24406337"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00972"/>
    <dbReference type="eggNOG" id="ENOG502QQA7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021993_0_0_1"/>
    <dbReference type="OrthoDB" id="413079at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000286">
        <property type="entry name" value="MFS efflux transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000308">
        <property type="entry name" value="MFS efflux transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051788">
        <property type="entry name" value="MFS_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514:SF3">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
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            <begin position="106"/>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
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            <begin position="164"/>
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="199"/>
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="228"/>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="280"/>
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="314"/>
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="8">
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        </location>
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        <location>
            <begin position="371"/>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="406"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="72"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
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        <source>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EFQ25828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="461" mass="49908" checksum="D5E3D19C0705AC11" modified="2011-01-11" version="1">MSQTATETRSDTQQHKPFGPDVFELGHLTSSHGRSLEDISLKLDGSEAHQSRTDDLDSAPPPYAHGTIERWNSPKGNVGRIVFAFFSFIISGMNDAAVGLETYYDLSYTIVSLIFLTPFAGYSVAAFTNARIHQKFGQRGVAIMAPLCHIVTYVVLSLHPPYPVLVVANMISGFGNGLTDACFCAWIGAMDKTNTIQGFLHASYSVGALIAPLIATSMVVTAKLPWYNYYYFMVGASVLELVGLTITFWPKTGAMYRAEHAHENEGQGGAGTRIALKSKVTWLCSVFFFSYMGVEVGLGGWIVTFMLRVRKASAYASGISATGFWAGQALGRACLGFVTERYGERLCISIYLVICIALQLLFWLVPQFIVSAIAVAFLGFFLGPMFPGAVTMTAKLLPKHIHVSAIGFAMAIGGTGGTVFPFIIGAIATSKGVTVLQPIVLSLIAVVAIVWLCFPRIQKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5Z7</accession>
    <name>E3Q5Z7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Eukaryotic translation initiation factor 3 subunit M</fullName>
            <shortName evidence="5">eIF3m</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_01389</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CSN7/EIF3M family. CSN7 subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the eIF-3 subunit M family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008092074.1"/>
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    <dbReference type="STRING" id="645133.E3Q5Z7"/>
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    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01389"/>
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    <dbReference type="HOGENOM" id="CLU_035254_0_0_1"/>
    <dbReference type="OrthoDB" id="10267031at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071541">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex, eIF3m"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045237">
        <property type="entry name" value="COPS7/eIF3m"/>
    </dbReference>
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        <property type="entry name" value="eIF3m"/>
    </dbReference>
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        <property type="entry name" value="eIF3m_C_helix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15350">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 7/DENDRITIC CELL PROTEIN GA17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15350:SF2">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18005">
        <property type="entry name" value="eIF3m_C_helix"/>
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    </dbReference>
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        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="7">
        <location>
            <begin position="187"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="394"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="394"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="428"/>
            <end position="454"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00008482"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ26245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="454" mass="52047" checksum="9F52BB94121FB937" modified="2011-01-11" version="1">MAAGAKQQAQPQLLFVDGSFQELAREMADYLHIAEEVKPLIENEAKKEEVLSKLVRSSAALSSVPEKEFTAASNLMIHLVLQSEDPKKHLPTLCQAFSKPIASSPVNGVGLSLNALSTIFNLITPENPIRFNVFMAILRFLKSHAMFEAIQPYLKHLPNWFEEWATSEEYQRQMYEEIAEVAKEAGKEEESYEYILKALRTFDADDKEEIGSEDAQRLSLRAVRDALLSNTHYLFTDIRSIPSVQNLSETHPVYSQLLDIFAEQDLEDYNDFNDEHEGFVEKERLDHEKLHRKMRLLTFASLAAQTTSRRIEYSAIAKALQVPSEEVEMWAIDVIRAGLVEGKLSQQDQVFLVHKVTYRVFGTRQWQELATRLDSWKGTFSNLYDVIRKEQANAKAQKERDAHEAERKAQNPGNEGGGSGGRQQRNQGRRDNQQREPREPREPREPKERTENDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6S4</accession>
    <name>E3Q6S4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02382</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090582.1">
        <property type="nucleotide sequence ID" value="XM_008092391.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6S4"/>
    <dbReference type="GeneID" id="24407747"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02382"/>
    <dbReference type="eggNOG" id="ENOG502R14R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1299632_0_0_1"/>
    <dbReference type="OrthoDB" id="4849300at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="41"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="220" mass="24495" checksum="8DD9CBC0CEA503C8" modified="2011-01-11" version="1">MFDSYMSVPTHIYNDEKGLGDIDELAEDIRHSRESLRRLVSRQASRATRASRASIESRGPLSSNEDLDLHVDLPRGILADESAASSRPPGHPSGKATRKKKRSSTTPRSERKAERDAEVQPAKRRRGFRAVLRRIFGLDDNPEAVTDSLYGKPEIHIPQKRNHRDRGKKRGHRDNGLRTSTKKKAAPERSTDHAEAESSSSKEPAPPPLALISPKNDTAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7D0</accession>
    <name>E3Q7D0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Fucose-specific lectin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_02588</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090788.1">
        <property type="nucleotide sequence ID" value="XM_008092597.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7D0"/>
    <dbReference type="GeneID" id="24407953"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02588"/>
    <dbReference type="eggNOG" id="ENOG502RVY9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028617_1_0_1"/>
    <dbReference type="OrthoDB" id="4696326at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.70">
        <property type="entry name" value="Fucose-specific lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89372">
        <property type="entry name" value="Fucose-specific lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179475" description="Fucose-specific lectin" evidence="3">
        <location>
            <begin position="24"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="382"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="467"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="488"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ26768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="502" mass="54386" checksum="EA04CE44CC3D41E1" modified="2011-01-11" version="1">MPGFSKYFLGAALLLASPATCLTAWYTALSPHVAMQDLETGNILYSACNSNSTPIFPTDGLNAFRIQRKPRNGTSLAAAGWYDVEGKTTVASLFFQAEDGSLINGYYLCDFASGHYVVKGEYTISATAAVTSIHNETGLSVELLGAEDGYRVYFHDEQKKVNAMAYTTKTDWHLEGLVSQDPVGGMGLASAHYSQQNITVIYAKDAENFETARYFKDDTWRLATLPRPLVGGQVSGKTNSSSITLDSSIKPNFTLPAFASDLTGLDVIVDRANVRNILYLGTDAKLHQVTNIGDQWKLMPDQESLQWPVADSPYGPFAATSNYETSEAWIWYPSNGNLVQLYQNATGSWTQATTVPSVNTTSTASQIPEAAKPVVLSTGAKAGIGIGISFAVVALAGVGLLLLKRRRRKQAAAAAEAARLKEAEATANGWGTYSPMEKHGSEVFEADAAPAPQELMDTVERFELVGEGHWREMDATGQNGARRSIGGWREEQKARGMQDEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7G2</accession>
    <name>E3Q7G2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Iron permease FTR1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_02620</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090820.1">
        <property type="nucleotide sequence ID" value="XM_008092629.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7G2"/>
    <dbReference type="STRING" id="645133.E3Q7G2"/>
    <dbReference type="GeneID" id="24407985"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02620"/>
    <dbReference type="eggNOG" id="ENOG502QQWE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046738_0_1_1"/>
    <dbReference type="OrthoDB" id="4364at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033573">
        <property type="term" value="C:high-affinity iron permease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015093">
        <property type="term" value="F:ferrous iron transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004923">
        <property type="entry name" value="FTR1/Fip1/EfeU"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31632">
        <property type="entry name" value="IRON TRANSPORTER FTH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31632:SF2">
        <property type="entry name" value="PLASMA MEMBRANE IRON PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03239">
        <property type="entry name" value="FTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0410">Iron transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="146"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="176"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="295"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="326"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ26800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="348" mass="37966" checksum="C7404E72FFE91307" modified="2011-01-11" version="1">MEDLFSLPIFFITFRESLETAIIVSVLLAFIRRTLATKDDPALQQKMEKQVWIGTAAGLLTCVLIAMAIISGIHSLGADRFAAAESVWEGIFSLSASLVITAMGAVLLRVTKLQDKWRLKLSKALNAGGSHAGPFRDRLKYLGEKYALFLLPFITVLREGFEGVLFIAGVGVSETAASIAASAVLGLALGAVVGYFIYRGSKKAPIQVFLIVSTCFLYLIAAGLFSKGVWHFEQNEWNKIVGGDAAELGSGPGSYDIRRSVWHVNCCNPDLNGGGFWGIFNAVLGWQNSATVGSVVSYNLYWVAVATGFFAMICKEKGYWPYSKRDKQQQQVSREGSDQEPLLSRPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q861</accession>
    <name>E3Q861_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal L37ae family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_02244</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL43 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091093.1">
        <property type="nucleotide sequence ID" value="XM_008092902.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q861"/>
    <dbReference type="STRING" id="645133.E3Q861"/>
    <dbReference type="GeneID" id="24407609"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02244"/>
    <dbReference type="eggNOG" id="KOG0402">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141199_1_0_1"/>
    <dbReference type="OrthoDB" id="10258345at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.30:FF:000002">
        <property type="entry name" value="60S ribosomal protein L37a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00327">
        <property type="entry name" value="Ribosomal_eL43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011331">
        <property type="entry name" value="Ribosomal_eL37/eL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002674">
        <property type="entry name" value="Ribosomal_eL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050522">
        <property type="entry name" value="Ribosomal_protein_eL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00280">
        <property type="entry name" value="eL43_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003058">
        <property type="entry name" value="PRK03976.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48129">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L37A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48129:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01780">
        <property type="entry name" value="Ribosomal_L37ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ27073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="92" mass="10056" checksum="73E395312C0C380F" modified="2011-01-11" version="1">MAKRTKKVGVTGKYGTRYGASLRKQVKKMEVSQHATYTCTFCGKPTVKRHSTGIWNCKGCKKTVAGGAYTVSTPAAAAMRSTLRRLREIAEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8K1</accession>
    <name>E3Q8K1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lactose permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_02043</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ26872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090892.1">
        <property type="nucleotide sequence ID" value="XM_008092701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8K1"/>
    <dbReference type="GeneID" id="24407408"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02043"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1073979_0_0_1"/>
    <dbReference type="OrthoDB" id="6133115at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF64">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ26872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="271" mass="30117" checksum="1A2A383F6FDB5249" modified="2011-01-11" version="1">MGFLKPSTTEKSKPDAQAVGSDLLAVLPEIPTPWYRTKHLLLLNLILLIPVLSSAAVGFDGLLICHHAGGDESSALVDYEIRQIKENIRLKTEAAKESSYPVSYYVNLVLNIVGITATKDQGLINGLLQLFNWIAAVFAGVMMTILTSVFSRTKDERASYAVAAFIFIYYFFHDIAWTPLLMAYPVEIFPFCNPIGLATLGWKYYIVFCILLTLLLFLIWLPFPETKGRTLQQIAEIFDGKNHRLGACGIGEGKADDAKVQEVEDYADTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8N8</accession>
    <name>E3Q8N8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">YCII-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_01897</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091422.1">
        <property type="nucleotide sequence ID" value="XM_008093231.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8N8"/>
    <dbReference type="GeneID" id="24407262"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01897"/>
    <dbReference type="eggNOG" id="ENOG502S8X0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110355_2_0_1"/>
    <dbReference type="OrthoDB" id="5519740at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1060">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051807">
        <property type="entry name" value="Sec-metab_biosynth-assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005545">
        <property type="entry name" value="YCII"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33606">
        <property type="entry name" value="PROTEIN YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33606:SF3">
        <property type="entry name" value="PROTEIN YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03795">
        <property type="entry name" value="YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YCII-related" evidence="1">
        <location>
            <begin position="43"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="144" mass="15976" checksum="0054ABF2D1C3CDA2" modified="2011-01-11" version="1">MSIPTRVLRNRFIPAARNLPRTASQTSPFSLRYRTMATSAKEFLCILPDKPDALARRLEVRATHLAGAQTNAGNGKIALGGAMFEEHPTEGKTPSFKGSVIIYTAKDAEEAWELIRDDIYAKSDVWDLEKAQVIPFKSAVRESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q990</accession>
    <name>E3Q990_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_01764</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091289.1">
        <property type="nucleotide sequence ID" value="XM_008093098.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q990"/>
    <dbReference type="STRING" id="645133.E3Q990"/>
    <dbReference type="GeneID" id="24407129"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01764"/>
    <dbReference type="eggNOG" id="ENOG502RU0H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055467_0_0_1"/>
    <dbReference type="OrthoDB" id="444631at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF129">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="312"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="94"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ27269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="467" mass="51518" checksum="F3E35DC47D0C4A6B" modified="2011-01-11" version="1">MASSDGFPSIPDDPSSLPLTGTSAFVGQPPATQDDYYIVKGLFRVTGTADVNPMMGYFLAAKPPPGYVHETRQISILVGLIFVILLVAVPTVLRIGLRLGKSSSMKFGWDDYTISIGALLALVFPITQIYTVAIGATAKHVWEVTYEQYSTGIVAAMVCRTAFYVAVGMIKLSMTIFIQRLAERLSIWWRISCYIFIASLVGYIGLAIFAIVFSCNPPAAQWDLALLGRIEPVPTCMDLEAQTQVLISIHVAQGLVLLFTPIVILWKVRVPTAKKARLFTIWIIGGLGVLGGLIQQTRPTVTNDLTWDYVEVLVWACLDLSLGTMAASLPVLDGLLEKYWMKAKSTVVNIFRGGQRRGKPGARVWPYSPTASDEEKRKKPTIRHSVSIIGAHTMRTESGASIVSNSQLQDSKSEVVEMGILRVQEVEVRISVVPEDVEKGQEMALDPRAPSPFWHNRPEWHDQTLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9X4</accession>
    <name>E3Q9X4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ras family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_02806</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091682.1">
        <property type="nucleotide sequence ID" value="XM_008093491.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9X4"/>
    <dbReference type="STRING" id="645133.E3Q9X4"/>
    <dbReference type="GeneID" id="24408171"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02806"/>
    <dbReference type="eggNOG" id="KOG0092">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041217_8_0_1"/>
    <dbReference type="OrthoDB" id="25896at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00154">
        <property type="entry name" value="Rab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001447">
        <property type="entry name" value="Ras-related protein Rab-1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24073">
        <property type="entry name" value="DRAB5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="150"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="296"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="195"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="296"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ27662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="321" mass="34963" checksum="306FB449EEBD6F04" modified="2011-01-11" version="1">MSSLEAKIVVLGSQNVGKTSLVMRYCKGSFNPAQTTSTVGASFMTKRVVDTDTDTMVRLQIWDTAGQERFRSISRLYYRGANACILCYSITDAQSFTEMGIWLTELRRNLPGDVVLHVVGTKADMVARDPSRREVPFERCIAYVAENLAPGQASTPPPTATPNGMPSLLSSSDPRQSSSQVYQSTSTFGGGGGEPRSPSSKRSSGFWGQEVGWDACHEISAESGEGVEEVFRVVTRKLVEQNRKMQQALLMAMATPGTPGYEAGMDGGYFDGMNPRGSFRVGRDRRSWLFSPNFSPAVTVEQGGTEQETDEAAGKARKRCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QA68</accession>
    <name>E3QA68_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02900</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091776.1">
        <property type="nucleotide sequence ID" value="XM_008093585.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QA68"/>
    <dbReference type="GeneID" id="24408265"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02900"/>
    <dbReference type="eggNOG" id="ENOG502RJ3U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1468055_0_0_1"/>
    <dbReference type="OrthoDB" id="5213862at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="152"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="184" mass="20749" checksum="EE472DEAA8B91D59" modified="2011-01-11" version="1">MGLSPPLFVVLIVLATIVPPLIAGALLTRFVCRNFRDAAGVVEPKPRRCWFGLRRVRSISSNATDSLATRAQSYADSWQDLESLRTHRDTPTPSLRYCTCEEVPPVRAPVPAAIRFQPQPPETWHPSRASRLTWSFSPTRRDQGHLRRSRSRLGSSKDSGVVLEGSSEEEWRARGERASRRMEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAA2</accession>
    <name>E3QAA2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Serine/threonine protein phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02934</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091810.1">
        <property type="nucleotide sequence ID" value="XM_008093619.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAA2"/>
    <dbReference type="GeneID" id="24408299"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02934"/>
    <dbReference type="eggNOG" id="ENOG502SN7S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094654_0_0_1"/>
    <dbReference type="OrthoDB" id="5409477at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="262" mass="29367" checksum="DF8E52AFB2610082" modified="2011-01-11" version="1">MYARDYRPRTPRTPRTRKTTVRMDPDCAICHAPASVACDCEAKGLDVAIKQAEQRMMQSIYNDIRSWVRAHAQDYILEYFRLLTERRKVAHAANIDRINATAYHYYHAAPHPSELAQAQADLKRGIDEDWQSSVQRYPEVLEYFFSLVDLTVPPDEDPIVKDPPLSALSGSRKQTGRRLAGGIPQPPARPPAITAAIGHERDPFARRTPPPMEPPGRLDRRTPGLGGRDRRSMPPMGHPGPPPGPYGRPPPQAPPGYYPWGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAJ5</accession>
    <name>E3QAJ5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_03027</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ27883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091903.1">
        <property type="nucleotide sequence ID" value="XM_008093712.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAJ5"/>
    <dbReference type="GeneID" id="24408392"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03027"/>
    <dbReference type="eggNOG" id="ENOG502R0QJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_200654_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="71" mass="7928" checksum="C113527C6FF55764" modified="2011-01-11" version="1">MPARQDAYSVSIPVSPPPPSDISTYMRSMHQHTKRQMEAANRSSTRRSGGRTSYPRMNGHNNESSSPDYSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QB54</accession>
    <name>E3QB54_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Transcription elongation factor SPT4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_03236</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the SPT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ28092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092112.1">
        <property type="nucleotide sequence ID" value="XM_008093921.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QB54"/>
    <dbReference type="STRING" id="645133.E3QB54"/>
    <dbReference type="GeneID" id="24408601"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03236"/>
    <dbReference type="eggNOG" id="KOG3490">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_138052_2_0_1"/>
    <dbReference type="OrthoDB" id="248751at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032044">
        <property type="term" value="C:DSIF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031934">
        <property type="term" value="C:mating-type region heterochromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033553">
        <property type="term" value="C:rDNA heterochromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000182">
        <property type="term" value="F:rDNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000993">
        <property type="term" value="F:RNA polymerase II complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003727">
        <property type="term" value="F:single-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006370">
        <property type="term" value="P:7-methylguanosine mRNA capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031507">
        <property type="term" value="P:heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008298">
        <property type="term" value="P:intracellular mRNA localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010507">
        <property type="term" value="P:negative regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001208">
        <property type="term" value="P:negative regulation of transcription elongation by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001209">
        <property type="term" value="P:positive regulation of transcription elongation by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032968">
        <property type="term" value="P:positive regulation of transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000232">
        <property type="term" value="P:regulation of rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090262">
        <property type="term" value="P:regulation of transcription-coupled nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140673">
        <property type="term" value="P:transcription elongation-coupled chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07973">
        <property type="entry name" value="Spt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029040">
        <property type="entry name" value="RPABC4/Spt4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009287">
        <property type="entry name" value="Spt4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022800">
        <property type="entry name" value="Spt4/RpoE2_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038510">
        <property type="entry name" value="Spt4_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12882">
        <property type="entry name" value="SUPPRESSOR OF TY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12882:SF1">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR SPT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06093">
        <property type="entry name" value="Spt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF025023">
        <property type="entry name" value="Spt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01389">
        <property type="entry name" value="Spt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63393">
        <property type="entry name" value="RNA polymerase subunits"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0137">Centromere</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="Spt4/RpoE2 zinc finger" evidence="9">
        <location>
            <begin position="15"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR025023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ28092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="123" mass="14116" checksum="D54EF707261E31D1" modified="2011-01-11" version="1">MSADNFVAPGQQRYLRACMVCSIVMTYARFRDEGCPNCEEFLHMAGSQDQIESCTSQVFEGLITLANPKRSWVAKWQRLDGYVRGVYAIKVSGQLPDEIRNTLEEEYRIHYIPRDGTETEVDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBW5</accession>
    <name>E3QBW5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_03344</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092220.1">
        <property type="nucleotide sequence ID" value="XM_008094029.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBW5"/>
    <dbReference type="GeneID" id="24408709"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03344"/>
    <dbReference type="eggNOG" id="ENOG502SX98">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1124439_0_0_1"/>
    <dbReference type="OrthoDB" id="5367448at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ28200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="243" mass="26951" checksum="316AC00EC9660C26" modified="2011-01-11" version="1">MSTNGHAILQTIQNKVASRTIQVTVVPRPTKFAERRAVLHSLQQFAKVEVFKKLDNHPSSFISVLSDKAKVKELVKISPLQYQLATPQTNGSVKTFLTSSASAGPFTNPAKHYDDEVAAHTEDRKDFTVHIFPAPTYIHSAAIKASPLHGPWPKSRRETVMSATLKESIPKNVAADGLSDWETGGQVKASGRGQLWEDILLGTKSNDVRKRAIIDRIQRREKSEKAPAIMEGLFHLRQEANKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBX1</accession>
    <name>E3QBX1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">methionyl-tRNA formyltransferase</fullName>
            <ecNumber evidence="1">2.1.2.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_03350</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.1.2.9" evidence="1"/>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092226.1">
        <property type="nucleotide sequence ID" value="XM_008094035.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBX1"/>
    <dbReference type="STRING" id="645133.E3QBX1"/>
    <dbReference type="GeneID" id="24408715"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03350"/>
    <dbReference type="eggNOG" id="KOG3082">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033347_0_2_1"/>
    <dbReference type="OrthoDB" id="10268103at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004479">
        <property type="term" value="F:methionyl-tRNA formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd08646">
        <property type="entry name" value="FMT_core_Met-tRNA-FMT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041711">
        <property type="entry name" value="Met-tRNA-FMT_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11138">
        <property type="entry name" value="METHIONYL-TRNA FORMYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11138:SF5">
        <property type="entry name" value="METHIONYL-TRNA FORMYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="Formyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Formyl transferase N-terminal" evidence="2">
        <location>
            <begin position="40"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ28206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="440" mass="48930" checksum="CAC7C7E9BA3FDFB6" modified="2011-01-11" version="1">MTWLALRPATFARVSVGLACRPGLRPYSAGAGPGISDPLRILFCGSDDFSCAALDALNAEKERNPGLIESLDVVVRPGKLSGRGMKKIREVPLKKLAEKLELPIHERDTFTGWQPRNDVNLIVAVSFGLFVPPRLLNLAKYGGLNVHPSLLPDFRGPAPLQHTLLQRRTHTGITLQTLHHKAFDHGTVLSQTPLPGIPVPEDCTTQRLHDIVTPLAAEMLVDGLRKGLHVPPLKTVGWQPNEDERKQLSHAPKVTNHDRQMNWPKWAADDVVLRQRVLGPVWCSAYHHGSRKIMRLKFGDAEVVERPDRIDQYYRRRSLRKRGELSAEDVPEEDQDVEMISWVWQPEGKAQDRESWMACRTPFFEHEDGESILIPTAGGSCLKLSTITVEGSRSKPAVTAVSGFGKVVRDEDDDGNRPDGLGDVWGPSIVGDLVFSIFDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBX8</accession>
    <name>E3QBX8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_03357</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092233.1">
        <property type="nucleotide sequence ID" value="XM_008094042.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBX8"/>
    <dbReference type="STRING" id="645133.E3QBX8"/>
    <dbReference type="GeneID" id="24408722"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03357"/>
    <dbReference type="eggNOG" id="KOG4177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004758_1_0_1"/>
    <dbReference type="OrthoDB" id="4833279at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056125">
        <property type="entry name" value="DUF7708"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF15">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24809">
        <property type="entry name" value="DUF7708"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="DUF7708" evidence="2">
        <location>
            <begin position="66"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="3">
        <location>
            <begin position="282"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ28213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1121" mass="125726" checksum="7AA422A6260C385B" modified="2011-01-11" version="1">MPKDDHASSGENSFIKARDDFIALLSESEKANFAKCSSVDELLQAIESLQHLGTRRSLVTRCLKKIKTFGDTLTPYFGIMEIFCGSNPEFANLALGGLLLVLKLASHFVTFFEKLSDVLSKIAARLPRYQELYDALSKDPGICSPSLTESLQKVYCHLFEFYGAVARIFSKKCGRIKRTPAILADLAWHPFDARFEQIIEKITFHQRIVKEELGYAKMGSLASTVRAVDQQRRMETAARLDLIEDAFNKQLQLKLNDAAMRWLDPPDIKTSLEHALDQKAEGTTEWLLEDSKFLSWRNYDRPEHHTGVETGTASQFLWISGKPGSGKTILSASTAEELGKCYTTNADYPPEVCYYIFNQTAGNSNSLAHVFRSIAAQIFHHFHKLERIRNIFVLASTGVQFQKAASENEVIETITQCLPHLPNLHFVIDGLDECKDVSKLVAWLLKWCETTPLKVMVASRPDVASLRRLAPKESRIEITASVLEQDIRCYLASQVDQLFREDLFPAHADQDHVVQCLLDHAEGMFLWVRLMVTFLSVPSMTKAQRLDSAVRPPSEGLDRLEDMYCRISQRLLSQDTHSKNLAQNTLTWAAHSSLQSPELREAICPEGWDMDDGSATTRFDHAVVLSCCGLIEKGPHGTYQYIHLTALDFVQRSSLIPPPPEAKAIMAGRCISYLAFSLPQKPLSGDIYKSADRTEVRRKWPLLQVSAAKWAALAIDALMMDDTTARNSEVVEEMITLGLRYLKMGLGLMVWIESLYTLGVATSLLGYQSSRQRYSLVGKFSGSSQSTIFLQGLEGLMEDVKVMHREWGPSLEESPAEIWRDVTAFTTSKFLVKTKAVHVETLASNLRIPGTQDPELSVKPTFSTSMTSPDGSLLANLGIFPSKYFRMGWNEHGDIPCYTYDGTISRPAGQAFSRVARCPQTLQEVQDTCVGWIARYEVFSIAGEASERMICTLHDLDAADIEICLRQGLWFSPVGGWKCRFPLTIDPGLHGFTLLNKVFLARKDGQRHRPTSLRIDFNETRRTIWGPCHTFSAGYSYEIFWSPDSKYLGFSDVTTAGDICLAVFDTSEGFASGRAPSLVKYASIKPCSNIMLACCQFHPTMPLLLFLEGPDIMLWRFQDAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QC69</accession>
    <name>E3QC69_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_03601</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092477.1">
        <property type="nucleotide sequence ID" value="XM_008094286.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QC69"/>
    <dbReference type="STRING" id="645133.E3QC69"/>
    <dbReference type="GeneID" id="24408966"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03601"/>
    <dbReference type="eggNOG" id="ENOG502SVPD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022039_0_0_1"/>
    <dbReference type="OrthoDB" id="5423493at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="170"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="335"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="413"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="529"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="556"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="596"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="623"/>
            <end position="632"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ28457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="632" mass="69293" checksum="67DE8D493473810A" modified="2011-01-11" version="1">MPRPKRARRAPPAPVAVAAPEEKLSPAPASGSDIYSHSDREHSVIRKELEKEDGGRSSRLAGRASARLSRSASLRQKQALEESVHARDEAMSRLEDELDMTSSKAKTESDQRQKSDSSLELELSRKTRATPVQHRRDTTGLDLDDEMFEGLDTTIGDDDDDAAAPRSDISTFSVTSAFSVSHFRRRGRAPSISISRDDAPIRPSSRGVGSTPGISSTFNIGLFKRRQREPSILGTAQKERAQRPIELSSGPDSDDEEADDGFDPDAESTPLQKRRKTQSLAAEPESDSQQVLAPDSQPAQNDMAPHSSTTWRKRKSTESHAESDRPGKASRTEPEPEPEPVPDLGDGDSDSELSDLPSPVLTPTRPSMFPQPTTPNRDEIMAPPESSDSEGSEGIWPDIHTLAKQRRRRASPVTPTRDGNVSDASSPPSLTHSPNFPATRNKSRQKKQGMSPKVTTADLTGLLPRRRHKKARDPYGVNDTEEEEVDASDHAEHDDELSYVDSRTRSRRAKAAPRDPGTANRPASRSVKAAASAERPRAATRSSTRTYSRRLSDKENEAEEETAEAEAEADAGAEGDNFAPVPDDVPESQDSSDPARSADELKKAARKFKEVDRWELEFEEVTEGSSPNRDAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCN9</accession>
    <name>E3QCN9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glutathione-dependent formaldehyde-activating enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_03771</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092647.1">
        <property type="nucleotide sequence ID" value="XM_008094456.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCN9"/>
    <dbReference type="STRING" id="645133.E3QCN9"/>
    <dbReference type="GeneID" id="24409136"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03771"/>
    <dbReference type="eggNOG" id="ENOG502SPQT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098340_0_0_1"/>
    <dbReference type="OrthoDB" id="3907216at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ28627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="241" mass="26712" checksum="EB75CE0BAB9A9889" modified="2011-01-11" version="1">MSGRSLHRALSGGCHCGRNSYIIDVPHSTTERAQVLFHTDSMHRVPLATPLAAMLRVPLSWYRSSTHALFPDEKYSTIRRVFEGSPNHSSKRHFCGFCGTPLSYWTEQPQTEAGYIHLTLASLRGEDLRDLEDLGLIPGFEEAEQQPAVPTTTTVIGRETRGVPWFESLIEGTRLGSMSRSQVVDHGNDGKIRVEWEIVEWTDSDDANNVAPTAEDVGMTTSLPGKRKMGDRDDAAGDAMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCT1</accession>
    <name>E3QCT1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_03813</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092689.1">
        <property type="nucleotide sequence ID" value="XM_008094498.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCT1"/>
    <dbReference type="GeneID" id="24409178"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03813"/>
    <dbReference type="HOGENOM" id="CLU_2621895_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ28669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="78" mass="8664" checksum="A7859576877B682B" modified="2011-01-11" version="1">MNSQNWTQYRGRCGAAGIAAFLGAPAAEPDLILQQPDCVEMGRRPTTPGTDWAIWQGDQIKLLPEMDSKDEDKGYPFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCX8</accession>
    <name>E3QCX8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Proteasome A-type and B-type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_03894</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092770.1">
        <property type="nucleotide sequence ID" value="XM_008094579.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCX8"/>
    <dbReference type="STRING" id="645133.E3QCX8"/>
    <dbReference type="GeneID" id="24409259"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03894"/>
    <dbReference type="eggNOG" id="KOG0179">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035750_1_0_1"/>
    <dbReference type="OrthoDB" id="268479at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010499">
        <property type="term" value="P:proteasomal ubiquitin-independent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd03757">
        <property type="entry name" value="proteasome_beta_type_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000027">
        <property type="entry name" value="Proteasome subunit beta type-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF2">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA TYPE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ28750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="263" mass="28982" checksum="C582DC1BF2339399" modified="2011-01-11" version="1">MAMFSQNPLMNGPNYSFSEAPKKANGEFRQHRFNPYTDNGGSTLAIAGADFAIMAGDTRSTSGYSINSRYTPKVFKIGGTTSTQEDATILLSVVGFAADGEALKDRLDTICKIYRYRHGKPMSVTACAKRLSTILYQKRFFPYYVYAILGGLDEEGVGAVFSYDPVGSYEREQSRAGGAAASLITPFLDNQVNFKNQYVPGSGVGHELQERPRVPLERKEAEILVKDAFDGAVERHIEVGDHLQMMVITKNGIEEVLLPLKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QD59</accession>
    <name>E3QD59_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_03975</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092851.1">
        <property type="nucleotide sequence ID" value="XM_008094660.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QD59"/>
    <dbReference type="STRING" id="645133.E3QD59"/>
    <dbReference type="GeneID" id="24409340"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03975"/>
    <dbReference type="eggNOG" id="ENOG502SH1E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052682_0_0_1"/>
    <dbReference type="OrthoDB" id="5419666at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="185"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ28831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="299" mass="32761" checksum="29F9DD464CEEF573" modified="2011-01-11" version="1">MSSISRAFTTRRVKNSIDLSDAARGKERTNILQRSKTTKAQYAIRHKISAPMELVHTTNMLSYNAPDIRPRTGTDASSNSSRKSTEEDSESARSAASSPPTSPDVAPHELLKEPNHLSCYFVSPGAPNNASKTPEVPTIPKRAPTHTKQASFDAVARQRSLSQMSKASDKTVSSKASMTFSARASSGSSAASTMSHHSITPAIKTPLPPMPTPAFQHQSPRQEKVTESHPFGRELAQVTEIAEEFGIKDDVMYEEERLLKAEGLYKFAADDYLSEVQSLFPNFFTDSQAPQRSMATAWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDZ2</accession>
    <name>E3QDZ2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Leukotriene A(4) hydrolase</fullName>
            <shortName evidence="14">LTA-4 hydrolase</shortName>
            <ecNumber evidence="14">3.3.2.10</ecNumber>
            <ecNumber evidence="14">3.4.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">GLRG_04224</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>an epoxide + H2O = an ethanediol</text>
            <dbReference type="Rhea" id="RHEA:19037"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:32955"/>
            <dbReference type="ChEBI" id="CHEBI:140594"/>
            <dbReference type="EC" id="3.3.2.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13 14">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="13 14">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 14">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the peptidase M1 family.</text>
    </comment>
    <dbReference type="EC" id="3.3.2.10" evidence="14"/>
    <dbReference type="EC" id="3.4.11.-" evidence="14"/>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093100.1">
        <property type="nucleotide sequence ID" value="XM_008094909.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDZ2"/>
    <dbReference type="SMR" id="E3QDZ2"/>
    <dbReference type="STRING" id="645133.E3QDZ2"/>
    <dbReference type="MEROPS" id="M01.034"/>
    <dbReference type="GeneID" id="24409589"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04224"/>
    <dbReference type="eggNOG" id="KOG1047">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014505_1_1_1"/>
    <dbReference type="OrthoDB" id="79562at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000328">
        <property type="term" value="C:fungal-type vacuole lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005771">
        <property type="term" value="C:multivesicular body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061957">
        <property type="term" value="C:NVT complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004301">
        <property type="term" value="F:epoxide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120113">
        <property type="term" value="P:cytoplasm to vacuole targeting by the NVT pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09599">
        <property type="entry name" value="M1_LTA4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.390.10:FF:000009">
        <property type="entry name" value="Leukotriene A(4) hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.320:FF:000001">
        <property type="entry name" value="Leukotriene A(4) hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1730:FF:000004">
        <property type="entry name" value="Leukotriene A(4) hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2010.30:FF:000001">
        <property type="entry name" value="Leukotriene A(4) hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2010.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.320">
        <property type="entry name" value="Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012777">
        <property type="entry name" value="LTA4H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049980">
        <property type="entry name" value="LTA4H_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038502">
        <property type="entry name" value="M1_LTA-4_hydro/amino_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034015">
        <property type="entry name" value="M1_LTA4H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015211">
        <property type="entry name" value="Peptidase_M1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02411">
        <property type="entry name" value="leuko_A4_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45726">
        <property type="entry name" value="LEUKOTRIENE A-4 HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45726:SF3">
        <property type="entry name" value="LEUKOTRIENE A-4 HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09127">
        <property type="entry name" value="Leuk-A4-hydro_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01263">
        <property type="entry name" value="Leuk-A4-hydro_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="4 14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 14 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 14" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 14" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 13 14" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M1 leukotriene A4 hydrolase/aminopeptidase C-terminal" evidence="15">
        <location>
            <begin position="504"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="334"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="421"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="174"/>
            <end position="176"/>
        </location>
        <ligand>
            <name>a peptide</name>
            <dbReference type="ChEBI" id="CHEBI:60466"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="304"/>
            <end position="309"/>
        </location>
        <ligand>
            <name>a peptide</name>
            <dbReference type="ChEBI" id="CHEBI:60466"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="333"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="337"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="356"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="601"/>
            <end position="603"/>
        </location>
        <ligand>
            <name>a peptide</name>
            <dbReference type="ChEBI" id="CHEBI:60466"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR612777-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR612777-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR612777-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EFQ29080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="646" mass="72432" checksum="9B03C439C504599A" modified="2011-01-11" version="1">MWRSLLAKGSIPLRTSFTRITSPQSRAAAFGSTTANMANTSGNRDPNTLSNYGAWLTKHTTANFTIDFKDKSLKGSVTLELESLTDKQSKEIILDSSFLSISSVKVNAATSTWELKDRVEPYGAPLHVFVPQGAAKGDIVKVDVDLATADKCTALQWLTPAQTGNKKHPYMFSQCQAIHARSLFPCQDTPDVKSTYTFVLASPLPVVASGVLVEGESEKKGDDTVYRFEQKVPIPSYLFALASGDIATAPIGPRSIVATGPDELEGSQWELQGDMEKFMEVAEKLVFPYRWGQYNVLVLPPSFPYGGMENPIYTFATPTIISGDKQNVDVIAHELSHSWSGNLVTSCSWEHFWLNEGWTTYLERRIGMAVHGDAERDFSSIIGWKALEDAVALFGKDSEFTKLIINHKGIDPDDAFSTVPYEKGFHFLYYLERLVGRDAFDKFIPHYFTKWSRKSLDSFEFKETFLDFFNGLGDDEIKNKVASIDWDKWFYQPGLPPKPEFDTTLADVCYELAERWKDDSFKPSPEDVASFSGNQKLVLLETIEKFPSPLSADRARLLGTTYDLVSSRNAELKTAYYKIALAAEDKSAYPGAAELLGHVGRMKFVRPMFRSLNKVDRELALKTFEKNRDFYHPICRGMVEKDLGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3QE67</accession>
    <name>E3QE67_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">dihydroorotase</fullName>
            <ecNumber evidence="4">3.5.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_04299</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 3/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.3" evidence="4"/>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093175.1">
        <property type="nucleotide sequence ID" value="XM_008094984.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QE67"/>
    <dbReference type="STRING" id="645133.E3QE67"/>
    <dbReference type="GeneID" id="24409664"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04299"/>
    <dbReference type="eggNOG" id="KOG2902">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041558_0_0_1"/>
    <dbReference type="OrthoDB" id="1670005at2759"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00117"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004151">
        <property type="term" value="F:dihydroorotase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000041">
        <property type="entry name" value="Dihydroorotase, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00219">
        <property type="entry name" value="PyrC_classII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004721">
        <property type="entry name" value="DHOdimr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002195">
        <property type="entry name" value="Dihydroorotase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00856">
        <property type="entry name" value="pyrC_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43137">
        <property type="entry name" value="DIHYDROOROTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43137:SF1">
        <property type="entry name" value="DIHYDROOROTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001237">
        <property type="entry name" value="DHOdimr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00482">
        <property type="entry name" value="DIHYDROOROTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00483">
        <property type="entry name" value="DIHYDROOROTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="9">
        <location>
            <begin position="9"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ29155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="358" mass="38710" checksum="A3A474B7C9DDD83F" modified="2011-01-11" version="1">MPLPDTVELPAGFDAHVHLRDGDMCKIVAPTVRQGGVNQALIMPNLAPTPVTTVKMALDYSARIKQAMGKDEVDLLMTLYLHPDVTPETIKEAKKAGVAAVKSYPAGVTTNSSAGVVDYDAFHEVFKAMEEVDLILCLHGECPSHAGSDITTLNAESKFLPTLKALHAKYPKLRIILEHCTTAEAVEAVKSCGPNVSGTITCHHLFITIDDVVGDALNFCKPVAKLPADRKALLNAVVHSNGKFFLGTDSAPHPITSKTGPSKAAAGVFTQPYAVQYLLAALDEAVARGELRDEDITQERLEGFVSGYGRKFYGTEDVRKERVRLTRGGAVVNQMFEGTGIQVVPFRAGKETWSLEWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEP1</accession>
    <name>E3QEP1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_04491</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093367.1">
        <property type="nucleotide sequence ID" value="XM_008095176.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEP1"/>
    <dbReference type="STRING" id="645133.E3QEP1"/>
    <dbReference type="GeneID" id="24409856"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04491"/>
    <dbReference type="eggNOG" id="KOG0575">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_46_0_1"/>
    <dbReference type="OrthoDB" id="408964at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005816">
        <property type="term" value="C:spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13118">
        <property type="entry name" value="POLO_box_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14099">
        <property type="entry name" value="STKc_PLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1120.30:FF:000004">
        <property type="entry name" value="Serine/threonine-protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.30">
        <property type="entry name" value="POLO box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033701">
        <property type="entry name" value="POLO_box_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036947">
        <property type="entry name" value="POLO_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345:SF0">
        <property type="entry name" value="CELL CYCLE SERINE_THREONINE-PROTEIN KINASE CDC5_MSD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE PLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82615">
        <property type="entry name" value="Polo-box domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="71"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="34"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="435"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="435"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="449"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="471"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="509"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="536"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ29347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="999" mass="112067" checksum="81B500511FFDA2AD" modified="2011-01-11" version="1">MAHRLVAKTGVDLEALSPRDANALRMPKAIEMKTSKPVVQLKAAKDKEPPPQPPASVEEPPASDRPNGAVYQVGKMLGKGGFAVCYTGYHLPDRKKYALKIVRSQMPSKMQQKFQTELQIHSKMNHKNIVQFFRAFSFHDCMYLVLELCTNGSLMDMVKKRKGLTEPEVRFYSVQVAGAIKYMHGKGIIHRDLKMGNIFLDHRMNAKVGDFGLAALLVTGRDMQTIRRTTLCGTPNYIAPEILQKGKKGHDHAVDIWSLGIIMFAMLTSKPPFQSTSTEEIYRRARERDYEWPNPETSQKYISEEAKDCVATMLEDADMRPEPDVIVQHPFFTCGYMPVEADMTTRLLTLPPDRSEFYADRMSSQLQAVSKKNMEDMCRECGVGPLAPVQVIHTQTWKEMAAEEKSGLTPMIPLGEDVVYRPFDDWLREKRHARALAASSSTRSDATSESHLSGSQTAPTGLFRQPPQSFAAQQRAQNRPPAVASTVRSRPQPEVAPQPAEVARPRSVRQFSAPESRNQLSEPPLRKSTAVRRTPLPTTQSTGSLPSHAMAPQSSNQPTVTMTGLLENLKISSDQTEKASLFSPTECPETVAGSKPDVVLERLRRLQAELERALNARTMAIISSKDTTPPHPNVVVKWVDYTNKFGLGYILNDGGVGCILRDIPTTEGSKTLTLPSACMLVRDAERHIERRHDESYPERHQPLPPKQDIHFYENNGETGLARVSVSSSQFRVPVYEDGTPGKLNPGKDVYEHRKRERVILWKKFANYMIAYGRDEPLPAEETVTRPMEFSGNNSQPSDLVIFYQRFGDVGCWVFGDGHLQFNFPDHTKIVLNAAGTWCHFWHLPIEAAQNLATTGSIGAAALDERAMLSYPLQTLLNFQTKPSAARSTRTTTTSRRRPEIPADLQGIPTANDFRRKIEFIKNAVKEWVTNGGLGNSAMDRDHRLRWGGYRETVMGNSFIKGVWVTVGARWGDSRLSAYIDPANPMEMGEEIDESKRRRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEX7</accession>
    <name>E3QEX7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">UbiA prenyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_04577</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093453.1">
        <property type="nucleotide sequence ID" value="XM_008095262.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEX7"/>
    <dbReference type="GeneID" id="24409942"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04577"/>
    <dbReference type="eggNOG" id="ENOG502SNAR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063928_2_0_1"/>
    <dbReference type="OrthoDB" id="434972at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13965">
        <property type="entry name" value="PT_UbiA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050475">
        <property type="entry name" value="Prenyltransferase_related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42723">
        <property type="entry name" value="CHLOROPHYLL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42723:SF1">
        <property type="entry name" value="CHLOROPHYLL SYNTHASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ29433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="229" mass="24766" checksum="B3518F8CE642E8D0" modified="2011-01-11" version="1">MLVPILALGILTAIIGNPLTTTAASALTIFSNLPRLLLWLWLNILVLSIANQRDPSGILEDSMNKPWRPIASGRISAAEAKHLLLGVIPFTVVLGIKLDVGYETLACICASSYYNDLGGADEHFLIRQFINGLAYPVYGVAALKLAAGAVDILPAAYTWLSLLGLVVGTTIQIQDLKDYEGDKARERHTFPVVLGDGFTRTPQTLGSLLHVSHFVVCGLLLNLKLVFYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>E3QF55</accession>
    <name>E3QF55_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Aspartate-semialdehyde dehydrogenase</fullName>
            <ecNumber evidence="4">1.2.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">GLRG_04637</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the NADPH-dependent formation of L-aspartate 4-semialdehyde (L-ASA) by the reductive dephosphorylation of 4-phospho-L-aspartate. Mediates the second step in the biosynthesis of amino acids that derive from aspartate (the aspartate family of amino acids), including methioinine and threonine, the latter of which is a precursor to isoleucine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-aspartate 4-semialdehyde + phosphate + NADP(+) = 4-phospho-L-aspartate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24284"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.2.1.11"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="11">
            <dbReference type="Rhea" id="RHEA:24286"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 2/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homotetramer; dimer of dimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the aspartate-semialdehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.11" evidence="4"/>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093513.1">
        <property type="nucleotide sequence ID" value="XM_008095322.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QF55"/>
    <dbReference type="STRING" id="645133.E3QF55"/>
    <dbReference type="GeneID" id="24410002"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04637"/>
    <dbReference type="eggNOG" id="KOG4777">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049966_1_0_1"/>
    <dbReference type="OrthoDB" id="1894490at2759"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00016"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00463"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00464"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004073">
        <property type="term" value="F:aspartate-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071266">
        <property type="term" value="P:'de novo' L-methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009090">
        <property type="term" value="P:homoserine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd18130">
        <property type="entry name" value="ASADH_C_arch_fung_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02315">
        <property type="entry name" value="ScASADH_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000200">
        <property type="entry name" value="Aspartate-semialdehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000016">
        <property type="entry name" value="Probable aspartate-semialdehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051823">
        <property type="entry name" value="ASADH-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000319">
        <property type="entry name" value="Asp-semialdehyde_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005676">
        <property type="entry name" value="Asp_semi-ald_DH_pep-lack"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012280">
        <property type="entry name" value="Semialdhyde_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00978">
        <property type="entry name" value="asd_EA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006416">
        <property type="entry name" value="PRK08664.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46718">
        <property type="entry name" value="ASPARTATE-SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46718:SF1">
        <property type="entry name" value="ASPARTATE-SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02774">
        <property type="entry name" value="Semialdhyde_dhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000148">
        <property type="entry name" value="ASA_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01103">
        <property type="entry name" value="ASD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="Semialdehyde dehydrogenase NAD-binding" evidence="15">
        <location>
            <begin position="8"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="14">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="14">
        <location>
            <position position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00050041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000148-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EFQ29493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="361" mass="38806" checksum="F2B3B65F5BBC6D57" modified="2011-01-11" version="1">MGEFPVKKCGVLGCTGSVGQRFILLLSQHPYLKLVAVGASSRSAGKKYRDAVRWKQASPMGDVADLVVRECKASEFADCDVVFSGLDSDVAGEIEMEFLKANLAVFSNAKNYRRDPLVPLVVPTVNLPHLDLIPHQRKHHSLEKGFLVCNSNCAVIGLVIPFAALQAAFGPVDQVSVVTMQAVSGAGYPGVSSMDMIDNVVPFISGEEDKLETEAQKILGRITPDLTAFENQTDLKVSASCNRVPVLDGHTACVSLRFARRPAPSAEAVKKALREYVSDAQRLGCPSAPESPIIVFDEPDRPQPRLDRDLGRGYSVSVGRVREDESGIFDIKFVALSHNTVIGAAGSSILNAEAAVLKGFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QF68</accession>
    <name>E3QF68_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_04650</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093526.1">
        <property type="nucleotide sequence ID" value="XM_008095335.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QF68"/>
    <dbReference type="GeneID" id="24410015"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04650"/>
    <dbReference type="eggNOG" id="ENOG502QWE7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001023_0_0_1"/>
    <dbReference type="OrthoDB" id="2149224at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032065">
        <property type="term" value="P:maintenance of protein location in cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13365">
        <property type="entry name" value="PH_PLC_plant-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053005">
        <property type="entry name" value="Nuclear_Pos-Cytoskel_Interact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024774">
        <property type="entry name" value="PH_dom-Mcp5-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28190">
        <property type="entry name" value="NUCLEAR MIGRATION PROTEIN NUM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28190:SF1">
        <property type="entry name" value="NUCLEAR MIGRATION PROTEIN NUM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12814">
        <property type="entry name" value="Mcp5_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="1632"/>
            <end position="1743"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="381"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="449"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="648"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="688"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="821"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1319"/>
            <end position="1405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1448"/>
            <end position="1557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1774"/>
            <end position="1828"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="75"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="206"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="290"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="509"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="571"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="602"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="648"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="697"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1330"/>
            <end position="1352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1385"/>
            <end position="1398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1448"/>
            <end position="1461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1491"/>
            <end position="1501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1537"/>
            <end position="1546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1788"/>
            <end position="1801"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ29506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1945" mass="211479" checksum="5577EF46E29DB034" modified="2011-01-11" version="1">MVTSLAADKPHLPPADADANDPFISPPGHAHHRYSAFDNESFALGPASSPDQAKRVLQAHIADTERRLDEAGKLGTALVQQRKELAERLKEVEEQETEGELAPELRAKLADIEKEFQDVARETARAFLPKQRVPSNEAAGGSPYVPDGKMARRSISPSKFEKLEVQATGSPSKLTVPNRKVRNQPGNRIHDIEFAAEISTSLIAQVRNLQSLLSEKDEELRDIKVDKSRLEIENENFQQRVKALDESENKYKDENWNLETQVHDLIAAQKDAADREKKLSQSLNVLQVAKNSVQKELDEAKVSLAKLAEEHERAVKHLELDLTTAKRNAASAETERNTLRRKVDDLMSQNTELAKAVSIQRGRMSDRDFVRGVSDEDLEAATDGFTPEHSPPQSPIKGTPRHAMLESETLKSSLLHAQRTIQSQKTVIHREKTEKLELKRLLQDTRDELEKLRTDAPPVPARRNRKVESREFKKPTRGLLGGHRSSRNEVYHDDPDWEEATEIGSPRTSPNARSSSIIRRPNSRPGSGYRPQYTDLSDDFETANETSDAAFETANERGTETEDFQTGIEDFSGDDDDDTETETESPSKGRDLRSQALAMTGGRNSYDSTASTSADEDEEYIEYRTPTSQHSHQRMRVRLSRGIINRQSRQLSEEPSFQGSPASAATNSAAGTPHAGGQSLFAELADLDNSDADSGGDTPNRSRSATGDSTASVPTFSRDMVDSSNMTDPVKKTAASGPMMVDSGMMTEPMAELPFFSTPSAVHEEGVVSVGSISAAQQVSRHLSVDDADANGSRSRPLSTISYSDAGAQYDVDMDEKLAQFPMPPSSLDSYTPPPPPPELSLSSIDAQDIEPVVEPETPPPAPPQLTITSLLSEAVEPKAEPEIVRPVPVLAFTPLVSEDVEPKAEPEVPLPTLTISTYLSEAVEPVAEPEVPPPVLSLSALHAHNLEPVAEPEILPPTLTLSALHSHDLEPVAEPETPPPALILSALHAHDLEPVAEPEVPPPALSLSALHSQNLEPVAEPEVVLPVPDLTLSALVSENIEPKEDPEQSRALAIIPAPVPVPAPAPSLPTLTLSSITSETVEPREEPEIPVVAPTLSLSAIATEHVEPKAEPEIISPVPVLSFSDLHSHNLEPRAEPEVLPPTLSLSSIVAEGVEPKAEPEITPKIPTLTFSLIAAENIEPNAEPEVVAPVPVLSLTPISSEDIEPKAERAPSLTLSSIAFSDIEPLAEPEVLPPAPPALSLSSISSENIEPKAEPETPAPLPAVLAYSEIRSEHIEPLAALLPPLGFSSVLSQHVEPVATPEPSALKPSFAFSTIESIETQPISPRSPKRDAFILPRDNMDSSYGDKDAPRTPSRNALMSSVFGRSKNKADDSTIIAEDETRQSPSETRLSETPESQRPFKDISTNANNHAARKPVIPMSDSGAQTALTSEAIEEMLLSKTKATSDKSLSSFGTPSTPGTVRIHRPSHDSLSSFATENKMDTGFRRPGSASSNLASTGSLPPLPSNHKEAIEAARTGSSHGSAVMGPPLWPASAMRNQRPQTPNGARPQSPLSISTSVNAAPSVRVSRAGAPYGGAEIHSPTKLSTMSRHSSVSSFVSEIDHRFNPHAEAAAASGFGPNTDPRMIQAITQTMIGEYLWKYTRKTGRGEMSDFRHRRYFWVHPYTRTLYWSDRDPATAGRSELRGKSVPIEAVRVVTDDNPMPPGLHRKSLIVISPGRTIKFTCTTGQRHETWFNALSYLLLRTTDEGQSDVEEMAGNLTQADVDEFNPQLDRRASSTARQRPPPSLSSYNSRTTRNQSPAVDMSMNPPTLTPTKHEAQAQRPPVGTLGRISGYFGTFSSLRSRSGAMSPSIYEASEVHDSAEDLREIIEKQDREADRLENVRACCDGKFGLDRPPHPKADMLTMNQASMMLAPSTTTLSGVGRPALILTRTPTPTLDPLRLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFN1</accession>
    <name>E3QFN1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_04813</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093689.1">
        <property type="nucleotide sequence ID" value="XM_008095498.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFN1"/>
    <dbReference type="GeneID" id="24410178"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04813"/>
    <dbReference type="HOGENOM" id="CLU_3068565_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ29669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="53" mass="6083" checksum="CFEE4E3ADF3AF745" modified="2011-01-11" version="1">MFYRKKKSASELPEVFGYDRDALVSLVKRRYQLLVDIGHLHPEAVRAPSKPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFP9</accession>
    <name>E3QFP9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04878</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093754.1">
        <property type="nucleotide sequence ID" value="XM_008095563.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFP9"/>
    <dbReference type="GeneID" id="24410243"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04878"/>
    <dbReference type="HOGENOM" id="CLU_2775787_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="69" mass="7556" checksum="D6CBA38388B4CA6E" modified="2011-01-11" version="1">MHLIADNQPKRSIEEALDYGPGRPWFYTCMDPSGQASRNRPHRRGARGTPCMSGASAAASERAPLGFRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFY5</accession>
    <name>E3QFY5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Signal peptidase subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_04964</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Essential component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Essential for the SPC catalytic activity, possibly by stabilizing and positioning the active center of the complex close to the lumenal surface. Essential for viability.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the SPCS3 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093840.1">
        <property type="nucleotide sequence ID" value="XM_008095649.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFY5"/>
    <dbReference type="STRING" id="645133.E3QFY5"/>
    <dbReference type="GeneID" id="24410329"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04964"/>
    <dbReference type="eggNOG" id="KOG3372">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068714_0_0_1"/>
    <dbReference type="OrthoDB" id="10261524at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005787">
        <property type="term" value="C:signal peptidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045047">
        <property type="term" value="P:protein targeting to ER"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007653">
        <property type="entry name" value="SPC3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12804">
        <property type="entry name" value="MICROSOMAL SIGNAL PEPTIDASE 23 KD SUBUNIT SPC22/23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12804:SF0">
        <property type="entry name" value="SIGNAL PEPTIDASE COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04573">
        <property type="entry name" value="SPC22"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016089">
        <property type="entry name" value="SPC22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00045670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR016089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ29820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="229" mass="25451" checksum="27D32645D4A0E810" modified="2011-01-11" version="1">MYNTMTRAQNTFGFFTSVAFFVAAIIALSDLVAPRAPSVGSLKTTNVQVVKGRPHYYSSKKEEYAIIKFSLDADLSDLFTWNTKQVFVYVTAEWPDSSKAAAGTNATNQAVIWDQIITSPSADHLANIGPAAMRKLKKSAEGKSIDPNRGKLRIKNQRPKYQITHPSSKIAETDKVVLKLHYNVQPWVGILTWNQNRDIGGWKALKGGVSKAFKLPALKVKENKDKKKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGI7</accession>
    <name>E3QGI7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_05119</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ29975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093995.1">
        <property type="nucleotide sequence ID" value="XM_008095804.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGI7"/>
    <dbReference type="GeneID" id="24410484"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05119"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_43_5_1"/>
    <dbReference type="OrthoDB" id="5290825at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015798">
        <property type="term" value="P:myo-inositol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015791">
        <property type="term" value="P:polyol transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000100">
        <property type="entry name" value="MFS sugar transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050814">
        <property type="entry name" value="Myo-inositol_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020:SF40">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="114"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="250"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="277"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="371"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="404"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="436"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="464"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="503"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="532"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="118"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="615"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="615"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="631"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ29975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="642" mass="70833" checksum="DB3FF79CD1578195" modified="2011-01-11" version="1">MADDKHIAAVPSGDYTASNIEKAHHGAAIDLNANVDAKIKNPLLGISRADLLRDVDAFAQEKGLQEYIPVLRKGALVAQDPTGYEEIDGAEALDQTEIQVLRDEVLHKWRIPKILYLTIITCSIGAAVQGWDQTGSNGANLSFPTVFGIGGTSHRDTLLVGLVNSAPYIGSAFIGCWLSDPLNNLLGRRGAIFFAANFCLWPVLGSAFAQSWPQLLACRLLLGIGMGAKASTVPIFAAENSPAPIRGALVMSWQMWTAFGIMAGTAANLAVARTGDIAWRLQLGSAFIPAVPLVLLIYVCPESPRWYIKKNRYPEAMKSLLRLRNHPVQAARDIYYIHTQLQVEAEIIGRSNYAKRFVELFTIPRVRRATLASFTVMIAQQMCGINIIAFYSSTIFKEAGTSDFNALLASFGFGMVNFLFAWPAIWTIDTFGRRSLLLFTFPQMAWTLLAAGLCTLIPGAGGAHLGLVALFVYLFAAFYSPGEGPVPFTYSAEVFPLSHREVGMSWAVATCLFWAAVLSITFPIMLADLGVIGSFCFYAGLNVVALVMIFFWMPETKQRTLEELDYVFAVPTRIFMKYQLTKALPYWFKRWVLFQRDATLEPLYKFDLTQEDHHGSETYEKTKIEQRDNKSGSASGVDVTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGT2</accession>
    <name>E3QGT2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Pre-rRNA processing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_05214</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ30070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094090.1">
        <property type="nucleotide sequence ID" value="XM_008095899.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGT2"/>
    <dbReference type="STRING" id="645133.E3QGT2"/>
    <dbReference type="GeneID" id="24410579"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05214"/>
    <dbReference type="eggNOG" id="ENOG502QZVV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006918_0_0_1"/>
    <dbReference type="OrthoDB" id="5596576at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059065">
        <property type="entry name" value="Ig_Tag1-like_4th"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059066">
        <property type="entry name" value="Ig_Tag1-like_5th"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046368">
        <property type="entry name" value="Tag1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055011">
        <property type="entry name" value="Tag1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35895">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35895:SF3">
        <property type="entry name" value="PRE-RRNA PROCESSING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26174">
        <property type="entry name" value="LEA-2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26150">
        <property type="entry name" value="LEA-2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26153">
        <property type="entry name" value="LEA-2L_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22786">
        <property type="entry name" value="Tag1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117070">
        <property type="entry name" value="LEA14-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="69"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="Tag1 C-terminal" evidence="3">
        <location>
            <begin position="459"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="domain" description="Tag1-like fourth Ig-like" evidence="4">
        <location>
            <begin position="584"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="domain" description="Tag1-like fifth Ig-like" evidence="5">
        <location>
            <begin position="721"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF26150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF26153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ30070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="845" mass="91400" checksum="EF2AD07A2C4491D7" modified="2011-01-11" version="1">MAEGEERSPLLAPKIKGRVEDDSSLSESAPLLSSSSATPRYDGEQDDPETSRAPSLASNRSDTKSSVRWGSIISILVLILLVIGIMVGCFFVPSAVQLYAKQAAVVEPTNLALESITAEGVQARVQANFRLDASRVHDATSRRIGKFTTWIARQLGTEKTTVGVYLPEYDGALLGTAVVPPLTINIVDGQTTKIDFIAELSPGDPEAYRSIANEWLDGKIDQLKVLGKADIPLKSGIFPLGTHSVSEVLVFEANQIPTLPQYNISRLNFRDVPDRDGKRTAVGADVTVTAYNEFPVSVDVPELGFEILVPNCNSFDPYILLADATTKPLAIKPRSDVTVNVSGIIRKLPKSLTRVCPNSKSSPLDKFLGQYMRGEAATVYVRGRKMPDSDTPDWVGDILSEITVPVPFPGQGFDNLIKSFSLTDVNFKLPDPTADPDDPDGAPKVSGTVEVLASLPKEMNFDINVTSLRATADVMYQHKKLGELNLDKWQPANSTRLEGTEKHEPLLKIMSRVIDAPLNITDGDVLTDVMQRLLFGGKEVLLDVKASVAIRVNTGLGVLVLKDVPAEGKIPVKPLPGDTVGNVHPQVGDVKIISTSSSSMTIEALVNVTNPTPYTAVVPYVNIHIVRDGFVLGSATAENMRVVRGMNRNLVVTATWNPAAGGEASRKVASDMISEYLSGRNVTIEVKTHRGTIPTVPMIGESLSKLNISIAAPKLHLPGEDKNEGHFIRDATFHLLSSTATFTLVSPLRYNTIYVDWINATAFYNHTEPVGRIVYDLPFEAPPGTSVTPRLPVSWSIGSVGYDAVKNALGGSLKLDANANVTVRIGNWRDTVWYEGQGLGASIRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHF0</accession>
    <name>E3QHF0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">adenosine deaminase</fullName>
            <ecNumber evidence="4">3.5.4.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_05456</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>adenosine + H2O + H(+) = inosine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:24408"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:17596"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. ADGF subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.4" evidence="4"/>
    <dbReference type="EMBL" id="GG697348">
        <property type="protein sequence ID" value="EFQ30312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094332.1">
        <property type="nucleotide sequence ID" value="XM_008096141.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHF0"/>
    <dbReference type="STRING" id="645133.E3QHF0"/>
    <dbReference type="GeneID" id="24410821"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05456"/>
    <dbReference type="eggNOG" id="KOG1097">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022829_1_0_1"/>
    <dbReference type="OrthoDB" id="7202371at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004000">
        <property type="term" value="F:adenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006154">
        <property type="term" value="P:adenosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046103">
        <property type="term" value="P:inosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000017">
        <property type="entry name" value="Adenosine deaminase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001365">
        <property type="entry name" value="A_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006330">
        <property type="entry name" value="Ado/ade_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11409">
        <property type="entry name" value="ADENOSINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11409:SF37">
        <property type="entry name" value="ADENOSINE DEAMINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00962">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Adenosine deaminase" evidence="10">
        <location>
            <begin position="259"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ30312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="592" mass="68282" checksum="7A5A5F61B1ADA1C1" modified="2011-01-11" version="1">MELAQEMINAHDKVIEGTSDGLKRRPRQVTVLDQARTRTAAAKKIEDPDEYFRQRLEITNREKTLAFDFRLTALASSREIEANAIIQAVKAQDQRLVYDAAEPRQGWGGQNHPRFPADHFLSNVHLINRTRLFAIATKMPKGAHLHIHFNACLQPHVLLGIAKNMDRMFITSDKPLPASGDGRTDEEARNSLHLCEIQFSILPPEKERPGDIFSPDYVKRQTMKYSHFLQEFPKKHNADPEEWLTSKLVFHEDEAHNVHQTVQGAWEKFNVKTRMMKGLFNYETAYRKYTQGILEDFVRDNIQYAEIRPNFMETNQLWTDDGTKQIDNKGIMKIIIDEFDQFQQRTNNSFDGLKVIYCTPRSFSNESVAFALDECFRFKKDWPKWIAGFDLVGEESKGRPLRDFVPEFLAFRKKCDESGVDIPFLFHCGETTEIGDDTDGNLVDALLLNSKRIGHGFSLARHPYIMEHMKKRGICLELCPISNEELGLTPRVSGHAMYNLLANNVHCTLNSDNGTIFRSSLSHDFYQAMVGKTDMTLHGWRQLIEWSLEHSCMSKEELAIVRAAWEKRWEEFLDWVIATYGNSEALEDDSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHG3</accession>
    <name>E3QHG3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">CBS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_05469</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697348">
        <property type="protein sequence ID" value="EFQ30325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094345.1">
        <property type="nucleotide sequence ID" value="XM_008096154.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHG3"/>
    <dbReference type="STRING" id="645133.E3QHG3"/>
    <dbReference type="GeneID" id="24410834"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05469"/>
    <dbReference type="eggNOG" id="KOG2118">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011310_3_0_1"/>
    <dbReference type="OrthoDB" id="5353557at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010961">
        <property type="term" value="P:intracellular magnesium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030026">
        <property type="term" value="P:intracellular manganese ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.580.10:FF:000006">
        <property type="entry name" value="DUF21 and CBS domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045095">
        <property type="entry name" value="ACDP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12064">
        <property type="entry name" value="METAL TRANSPORTER CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12064:SF97">
        <property type="entry name" value="METAL TRANSPORTER CNNM-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0129">CBS domain</keyword>
    <keyword evidence="5 7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 7 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="61"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="11">
        <location>
            <begin position="57"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="322"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="406"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="494"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="581"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="682"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="500"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="537"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="600"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="740"/>
            <end position="753"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ30325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="753" mass="80476" checksum="04FDC98AF5BB0FEE" modified="2011-01-11" version="1">MATRGVVPIRRAHNASGFGLFRTAVLGLTKALTLGVSTVAAAPIHAVNHPDREPEAEGSSFWVLMGASIALVLLGGAFAGLTIALMGQDSIYLQVLAGDPDESQSRNAKRVYDLLKKGKHWVLVTLLLSNVIVNESLPVVLDRCLGGGVEAVVGSTVLIVIFGEVVPQSVCVRYGLQIGGYMSKPVLLLMWLMAPIAWPTAKLLDWALGEDHGTVYKKSGLKTLVTLHKSLGEVGERLNSDEVTIISAVLDLKEKPVENVMTPMDDVFIMAEDTVLDEKTMDIILSEGYSRIPIHATGKPTDFVGMLLVKILITYDPEDCLQVKDFPLATLPETRPETSCLDIVNFFQEGKSHMVLVSEYPGADYGAIGVVTLEDVIEELIGEEIIDESDVYIDVHKAIRRMTPAPKARTPKKTVLPSPRVIPQNGNLTEFGEEPRERHGSVGALSDVSENNLSSSAPRTTFLMRRSSTGPDGRMTSSAVPVKATFDEAKQHLKHLGPSNRASNPKNTKSTTVKIKPVQAGVPLSQIHTPASVAGDVNDHGLDEDTDEHTPLMRPKLTGKGAVHAIRKSYGGAGMSEAQARLSSAAHDAEDDKAAGEINVPSTVPENNGSKTAASGSPEAGRTDLTIIVSPGQASSGTSVISPVEDDFATPKRRPLVRSGSISENVFETSSGVRKIIIQAASSDSDETTSKGSSGHRSGSFGKVNVRTSGRNAEGEENDGDGMSNTDPSINNNSSSQQASKKKNRRKKRKNKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHH2</accession>
    <name>E3QHH2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">1,3-beta-glucanosyltransferase</fullName>
            <ecNumber evidence="9">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_05478</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cell membrane</location>
            <topology evidence="1 9">Lipid-anchor</topology>
            <topology evidence="1 9">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glycosyl hydrolase 72 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="9"/>
    <dbReference type="EMBL" id="GG697348">
        <property type="protein sequence ID" value="EFQ30334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094354.1">
        <property type="nucleotide sequence ID" value="XM_008096163.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHH2"/>
    <dbReference type="STRING" id="645133.E3QHH2"/>
    <dbReference type="GeneID" id="24410843"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05478"/>
    <dbReference type="eggNOG" id="ENOG502QPST">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021855_2_1_1"/>
    <dbReference type="OrthoDB" id="421038at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042124">
        <property type="term" value="F:1,3-beta-glucanosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071970">
        <property type="term" value="P:fungal-type cell wall (1-&gt;3)-beta-D-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004886">
        <property type="entry name" value="Glucanosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012946">
        <property type="entry name" value="X8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31468">
        <property type="entry name" value="1,3-BETA-GLUCANOSYLTRANSFERASE GAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31468:SF2">
        <property type="entry name" value="1,3-BETA-GLUCANOSYLTRANSFERASE GAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03198">
        <property type="entry name" value="Glyco_hydro_72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07983">
        <property type="entry name" value="X8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00768">
        <property type="entry name" value="X8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 9" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="8 9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005127988" description="1,3-beta-glucanosyltransferase" evidence="9">
        <location>
            <begin position="21"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="491"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="X8" evidence="11">
        <location>
            <begin position="366"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ30334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="513" mass="55489" checksum="471F1FD9AECA5B59" modified="2011-01-11" version="1">MGKLWVAALSALVLAHNASALEPIIMKGTKFFYTNGTQFFMKGIAYQQDTAAAGGESVTGEYKDPLAEEAACRHDIPILVEAGTNTIRTYAIDPKNDHSACMEMLSDAGIYVVSDLGEPKLSINRETPQWNTELYDRYTSVIDALAQYDNTIGFFAGNEVSNDKSNTEASVFVKAAVRDAKKHIKEKGYRWMGVGYAANDDKDIRANSARYFNCGDQDAAIDFWGYNIYSWCGENTLNYSVPVFFAEYGCNQPSGGDDRIFQETTALYEREMTDAFSGGIVYMYHQEANDFGLVEIKDGQAEAMKNYYELASRVLNANPTAIQMDSYEPSNTPAECSNTASNWEVQGDTLPPTPDKYLCECMVKSLSCIPKSNLEAEAIGDIFGYVCGASSDSCEGINTDPSTGVYGAFSMCSDEQKFAYVMNDYYKAQRSTRAACDYEGQGEIVSPSADDTCKKALASVADTTSASSTARPSSSSTGNAAAGPHQPVFNLGGFAIGAYLIASGCVGAAIIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHN1</accession>
    <name>E3QHN1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05513</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EFQ30369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094389.1">
        <property type="nucleotide sequence ID" value="XM_008096198.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHN1"/>
    <dbReference type="GeneID" id="24410878"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05513"/>
    <dbReference type="HOGENOM" id="CLU_2527328_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="84" mass="9645" checksum="DA69ACD8F0594380" modified="2011-01-11" version="1">MLDDYPCNLPVTALYAYDRYPWPSSGKAESRFANSQRSDRAGSYDEKPIARANFNKRILLYASQNFKLILRTSLHGAFDYNSIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHN8</accession>
    <name>E3QHN8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyl hydrolase family 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_05520</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glycosyl hydrolase 12 (cellulase H) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697349">
        <property type="protein sequence ID" value="EFQ30376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094396.1">
        <property type="nucleotide sequence ID" value="XM_008096205.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHN8"/>
    <dbReference type="STRING" id="645133.E3QHN8"/>
    <dbReference type="GeneID" id="24410885"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05520"/>
    <dbReference type="eggNOG" id="ENOG502SH4Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051064_0_1_1"/>
    <dbReference type="OrthoDB" id="89349at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013319">
        <property type="entry name" value="GH11/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002594">
        <property type="entry name" value="GH12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34002">
        <property type="entry name" value="BLR1656 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34002:SF10">
        <property type="entry name" value="PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01670">
        <property type="entry name" value="Glyco_hydro_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="21"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ30376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="267" mass="29939" checksum="9A3284EBB5776A93" modified="2011-01-11" version="1">MGSCCSTSDDSSPHELEPARPAQPPLNMPPPPNHIVSLEKKWAYHAVDGYELNNNTWGLESATSGSQRTHYDGPSPPGASGAVGISWSSDWEWRGGEHNVKSYVYGARQFERRLLSEIQAMPTEAEWHYSTWDVRANVAYDIFTDPDKDHANSSGEFEVMIWLAKLGGVWPISESKAPIAHVEICGHQWELHFGYNHGGAMKVYSFLPVNGPIQHFNADVKQFFNFLSHQFEFPQHNQYMLVYQLGTEAFTGGPAEFVVPKFIANVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QI76</accession>
    <name>E3QI76_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_05835</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094711.1">
        <property type="nucleotide sequence ID" value="XM_008096520.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QI76"/>
    <dbReference type="STRING" id="645133.E3QI76"/>
    <dbReference type="GeneID" id="24411200"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05835"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_13_4_1"/>
    <dbReference type="OrthoDB" id="268400at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF164">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="282"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="312"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="393"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="427"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="472"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="499"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="537"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="569"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="145"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ30691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="606" mass="66086" checksum="B6B986F8B3D712E5" modified="2011-01-11" version="1">MESAAAAPQLPEPIHPGDPPRYPRQSTVSSLAASNWPLEDEKTVHHGFGFQTTELKRANSHDSSSTAFEKDLEHVDSFESSFDDDQAKEKAKEGVLYHDGQLILQPAPTQDPRDPLNLPLSRKVIACACLCCFGALAAAAELILGAMLPVFALEYSGLDPKLLKPLTSSGGLPGGSDPLKILANLPGAPPIFQIYLLASLPVLIIGVANLILVPMAISVGRRPVVLATGLLAVIGCIWSGSSQSLTSHLLARCVQAIGAGTVESLVPFIIQDMVHVHQRNSWISGIFAIQGLIIIVLGIAAPYVIINLSWRYMYFITAISAAFFLVGVYFFLPETKWHRTRDEMNGIPRDETGQKHSPRTFQYNIALFHGKMEWRKGWNAFVDTLRTFFYPQIFFITMLNSVMIACAFAAGYTVAPALLTAPWSWDFMLLGLCLLPVLIAAVAVAFVTGSAADWMANRLAKKRGVRVPENQLINLVFPTLAGIIGSILFGLAGSDQNNYSYVTFLTGLGLMAFGFLGANSIGAVYVLECYPHLAGPALVNIASFRCLLAFALSFKISDWVVEMGYFNAMMIYTGLISGFAVFIPVVYYYGPAWRKKWPADSFGDQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QI85</accession>
    <name>E3QI85_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Translation initiation factor eIF2B subunit alpha</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">eIF2B GDP-GTP exchange factor subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_05844</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">Component of the translation initiation factor 2B (eIF2B) complex which is a heterodecamer of two sets of five different subunits: alpha, beta, gamma, delta and epsilon. Subunits alpha, beta and delta comprise a regulatory subcomplex and subunits epsilon and gamma comprise a catalytic subcomplex. Within the complex, the hexameric regulatory complex resides at the center, with the two heterodimeric catalytic subcomplexes bound on opposite sides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the eIF-2B alpha/beta/delta subunits family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094720.1">
        <property type="nucleotide sequence ID" value="XM_008096529.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QI85"/>
    <dbReference type="STRING" id="645133.E3QI85"/>
    <dbReference type="GeneID" id="24411209"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05844"/>
    <dbReference type="eggNOG" id="KOG1466">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016218_0_1_1"/>
    <dbReference type="OrthoDB" id="10249309at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005851">
        <property type="term" value="C:eukaryotic translation initiation factor 2B complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002183">
        <property type="term" value="P:cytoplasmic translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904262">
        <property type="term" value="P:negative regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903833">
        <property type="term" value="P:positive regulation of cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1900036">
        <property type="term" value="P:positive regulation of cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045948">
        <property type="term" value="P:positive regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="entry name" value="Translation initiation factor eif-2b, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1070">
        <property type="entry name" value="Translation initiation factor eIF-2B, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051501">
        <property type="entry name" value="eIF2B_alpha/beta/delta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042528">
        <property type="entry name" value="elF-2B_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45860">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45860:SF1">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 10" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ30700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="329" mass="36052" checksum="09FF9E61157332BA" modified="2011-01-11" version="1">MPIRNKTTGDFDIVSTYHSLLQDPDLTKPVAAIEALISLLNASGTTTVYETLDLVKRASNTLHASVNNPVPLQAGTDLFLQYLVSSLKQQEGQSAATNPHQSFDAVRTHLLRNGRLFASRAIAARDRIADAGWRFVRDGKVVLTHGASRAVSTLLFRAADQFGDGGVRFKVVYVRDEHRPAESDRVVRELREKGIPVAEIAEPAVAHVLGLLRQVHMVIVGAEAVTQNGGIISRMGTYQIAKLAKQAGLPFYVAAESHKFVRKVPLDQRDLGFKQHVLDFRTDGASVQPEDAVDYTPPDFISNLVTENGVKLPSYVFEQLLDIYGSLNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIC8</accession>
    <name>E3QIC8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome P450 CYP2 subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_05682</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094558.1">
        <property type="nucleotide sequence ID" value="XM_008096367.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIC8"/>
    <dbReference type="STRING" id="645133.E3QIC8"/>
    <dbReference type="GeneID" id="24411047"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05682"/>
    <dbReference type="eggNOG" id="KOG0156">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_2_0_1"/>
    <dbReference type="OrthoDB" id="1103324at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ALNH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ30538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="351" mass="40584" checksum="4CFA2E1610E66A23" modified="2011-01-11" version="1">MVTLRMGSKTWVVLNSDHVVSEIIAKRGKNTNERPHMPVASDLVSNGKRTVIRQEKEWREGRRVTHQLLSGSNLKVYAGMQELESVDMLRRYLREPSLWFAHSYRYATSVLYRIVMGYPLNKTKAQLDDYQMVTIQFVTSINRSYVDFFPSLSRLPHFLQPWRRFWAKMGSFHRRVFQEWFSGDDEEAMYLATSVMAARGDNTRMTINVFIMAMATRPETRSRAREEVDRVCTDGESLKLPRISDLSAMPYVAAMIKEVLRWRPTVPIIPPHQLTGDLEFDGHFIPAGTCFLINSIGLSSEFDNPHEFRPERWIDNSGADMIPNFWGFGGGRRTSFNGPIDDKRLNHQALN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIJ6</accession>
    <name>E3QIJ6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyl hydrolase family 18 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_05750</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094626.1">
        <property type="nucleotide sequence ID" value="XM_008096435.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIJ6"/>
    <dbReference type="STRING" id="645133.E3QIJ6"/>
    <dbReference type="GeneID" id="24411115"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05750"/>
    <dbReference type="eggNOG" id="KOG2806">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015088_0_0_1"/>
    <dbReference type="OrthoDB" id="4851062at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ30606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="900" mass="100869" checksum="A14293E85C947F91" modified="2011-01-11" version="1">MDCYPAILGWSGGGRVCGGIDPGRLRVFCCAPPSGEPLFLPVPLKDLFPSPPTGDDVKTKFDLNIDNTWGDGEADNNSEDEPNEAAFQFHVLASPGEIQTSLDKRDGSHWEVFNCTEAVSEGEHTVQMVCTDSSERSNYGDIYKGHGVEGTILEMPQNRDCGLGKHAVAKSLEPAGNQFLPQHLVERKLLHDATIYDLKFDYNFTRVPWGFGPTQLRVDFSNQEGYWNKIVAAPSSKKSKRTLDEVGGNHRRWLEEECRDDYHRGSVSREELYRRWFGDDALQWLKELLHIDVTVEKRHDYEEVSAIILKEDWTCGPFRAKIDAVATAAIEMSTSFGITIITELGANLNLSKSYVHFNNEGSIEAILTIDALMKLEWNSGVFTIVPLPIPGVGPRFGLNARFKARVSIEDRIEAKAELANWEIRQTYPQQDDYKPKEIESANRQFPTDGIASPSFEVSVTAQGYAEAHIIPTLAFGIKFDKQWDLEDAEIELYGDLYGRVRAMSDLVGGDCLFGYKVEAGVKLMADAHLNKRIIPEGDKEWECVTAETKRHIEGRGESRNSSHSLIGKPSLRKRLVPYEPLVKLPDAEKLCPVEGNQGAQDCADTQNVFEFYDDSTSDAHPVEFRKRSIFDDDGGSLFAKGPFNETDDYNDYSDDQEYGTSASEMHLVERGPLAKRAPGKKLAICNGAHQFHIKKWDTSGTFDIYDNADWADCSNYDFVIQATRQRVPYTTRAGNPALEEYPVEHVLEAQMVVLFFETTAFSDLCFDMEETGSGWFDTNAVDPIVPRAPRRSPWQYIADAWPYSRGTETRSRIPYPAHKEDDFVFVIGPVSNIKSKAFQNFPALSGTDDMGRAVASEATVGDAIRTMKTALMLWKYLTTGAIRDTLVAQATRVGDRMEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJF2</accession>
    <name>E3QJF2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycosyl transferase family 25 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_06134</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 25 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ30990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095010.1">
        <property type="nucleotide sequence ID" value="XM_008096819.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJF2"/>
    <dbReference type="STRING" id="645133.E3QJF2"/>
    <dbReference type="GeneID" id="24411499"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06134"/>
    <dbReference type="eggNOG" id="ENOG502SHN6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032992_1_1_1"/>
    <dbReference type="OrthoDB" id="47375at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06532">
        <property type="entry name" value="Glyco_transf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050757">
        <property type="entry name" value="Collagen_mod_GT25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002654">
        <property type="entry name" value="Glyco_trans_25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10730:SF53">
        <property type="entry name" value="GLYCOSYLTRANSFERASE 25 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10730">
        <property type="entry name" value="PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01755">
        <property type="entry name" value="Glyco_transf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyl transferase family 25" evidence="4">
        <location>
            <begin position="9"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ30990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="309" mass="34752" checksum="A91F176EC5DF6295" modified="2011-01-11" version="1">MLLQAALSDMDIELFDGVPGDTVSEKAIPKTSEYNRQDDGVIGCWRSHMNAIGEIVRRNLSSVLILEDDVDWDIRIRSQLHDFALSTQALTQPLRSTLLSGGDPTLGTALEIPFENLPATAAPKFSPYGDNWDLLWIGHCGMHFPFLDQEGVPKARVIHHNDVTVAPKKNLRGLNLPFTLKENYPEHTRAVHHVREGVCTLGYAVSQQGARKLLQEVALKDVDDPVDLLLRYFCEGVKGRKPHKCLTSQPAFFHHHRAAGPMSSHSDIRNYKGFRETGMTYMVRWSVRLNADALLEGRTDFIDQYPDDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJS0</accession>
    <name>E3QJS0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_06252</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697353">
        <property type="protein sequence ID" value="EFQ31108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095128.1">
        <property type="nucleotide sequence ID" value="XM_008096937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJS0"/>
    <dbReference type="GeneID" id="24411617"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06252"/>
    <dbReference type="eggNOG" id="ENOG502RPBI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2589604_0_0_1"/>
    <dbReference type="OrthoDB" id="4850618at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="80" mass="9054" checksum="95E3D9DA314E6D38" modified="2011-01-11" version="1">MSGSSYKRPKSSYPQSAYSGSTNTTGRPRDTPTYQAPYTTYLSTADPMERFWVTGQGSHRTRHAADELAKFNQQWSSARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJW5</accession>
    <name>E3QJW5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein S15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_06297</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS15 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697353">
        <property type="protein sequence ID" value="EFQ31153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095173.1">
        <property type="nucleotide sequence ID" value="XM_008096982.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJW5"/>
    <dbReference type="STRING" id="645133.E3QJW5"/>
    <dbReference type="GeneID" id="24411662"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06297"/>
    <dbReference type="eggNOG" id="KOG2815">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078264_0_0_1"/>
    <dbReference type="OrthoDB" id="441444at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00353">
        <property type="entry name" value="Ribosomal_S15p_S13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000589">
        <property type="entry name" value="Ribosomal_uS15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005290">
        <property type="entry name" value="Ribosomal_uS15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="uS15_NS1_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23321">
        <property type="entry name" value="RIBOSOMAL PROTEIN S15, BACTERIAL AND ORGANELLAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23321:SF26">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US15M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00312">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01387">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="S15/NS1 RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="40"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="220"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ31153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="320" mass="36343" checksum="56AC70D8EAAB9FFE" modified="2011-01-11" version="1">MPPRLQSLQRLGTASLCLRPAVRPATPSFLPVIQTANISQREKKRKAKQDPYRHQQALQRKAANVKRQSEIQAERDAKWGDPVHGIPTPFVESFDSAGQASTTKIVKDDNGNVISEPRPLPTSPNLLNHLVTKEELQHVIQKAYVLTKPVKSDIQDYVDPAAEDLAEKKHQENHAKAVEALNRILSMDNANSKILFHTNIKRCIDEFGRHKTDEFLRQKPKSALVNPNAPPPPPRAGPDTGSSEVQIAILTAKIRKLAQELSQNRGYKDKHNKRNLRVLCHRRQRLLKYMEKNERGSERWTHMLEKLGLSPATYKEQISF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKL4</accession>
    <name>E3QKL4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4185 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_06546</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697355">
        <property type="protein sequence ID" value="EFQ31402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095422.1">
        <property type="nucleotide sequence ID" value="XM_008097231.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKL4"/>
    <dbReference type="GeneID" id="24411911"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06546"/>
    <dbReference type="eggNOG" id="ENOG502SRUP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061840_0_0_1"/>
    <dbReference type="OrthoDB" id="2583188at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025442">
        <property type="entry name" value="DUF4185"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13810">
        <property type="entry name" value="DUF4185"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4185" evidence="1">
        <location>
            <begin position="190"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="348" mass="38542" checksum="012CE9B8579EDEE9" modified="2011-01-11" version="1">MDSTKAVGTNPIVEPKVEYLGLQKADNSCSHRDLGFTGAIADKWYAVWGDVLWCDGGVTEPENDTPGFHGMVRDAVSAMTDDPLLVHDLSLGDNQRQRQFIPFNPSWGERFDTGFGGTSLVETNAAAGTGAVFYLVNQNAAGLIGAGIAKVDVINGTPVVTKRYGERGYWWPAAGNPRYGDIAAFRDPLSDWIYAWGGPPTTVLSSDWLQNNYVYLVRVRACEAFDLSKYEYWWGRQRGWRMDRLTIFTPETAAVWGTGQGQVVWNEFYHRYIFVHLGIGGGSVFLRTAHSPEGPWTPDLKIFEAQPIDGGLVYAGVAHPYLDESGKTLVISFTNNNRIQVIRATFSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>E3QL66</accession>
    <name>E3QL66_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">ADP/ATP translocase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">ADP,ATP carrier protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">GLRG_06893</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell. Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane.</text>
    </comment>
    <comment type="function">
        <text evidence="16">Catalyzes the exchange of ADP and ATP across the membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ADP(in) + ATP(out) = ADP(out) + ATP(in)</text>
            <dbReference type="Rhea" id="RHEA:34999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:35000"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 16">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="16">Membrane</location>
            <topology evidence="16">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="GG697356">
        <property type="protein sequence ID" value="EFQ31604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095624.1">
        <property type="nucleotide sequence ID" value="XM_008097433.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QL66"/>
    <dbReference type="STRING" id="645133.E3QL66"/>
    <dbReference type="GeneID" id="24412258"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06893"/>
    <dbReference type="eggNOG" id="KOG0749">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_12_0_1"/>
    <dbReference type="OrthoDB" id="270584at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005471">
        <property type="term" value="F:ATP:ADP antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140021">
        <property type="term" value="P:mitochondrial ADP transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990544">
        <property type="term" value="P:mitochondrial ATP transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000001">
        <property type="entry name" value="ADP,ATP carrier protein, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002113">
        <property type="entry name" value="ADT_euk_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45635">
        <property type="entry name" value="ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45635:SF14">
        <property type="entry name" value="ADP_ATP TRANSLOCASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00927">
        <property type="entry name" value="ADPTRNSLCASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0050">Antiport</keyword>
    <keyword evidence="11 14 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 14 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 15" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="116"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="13"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="118"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="218"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU368008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EFQ31604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="315" mass="34090" checksum="E85D21EC5C0DD99F" modified="2011-01-11" version="1">MSPPTEQKVLGMPPFVADFLMGGVSAAVSKTAAAPIERIKLLIQNQDEMLKQGRLDRKYEGIVDCFKRTAADEGVMSLWRGNTANVIRYFPTQALNFAFRDKFKKMFGFKKERDGYAWWMAGNLASGGAAGATSLLFVYSLDYARTRLANDAKSAKKGGERQFNGLVDVYRKTLASDGIAGLYRGFMPSVAGIVVYRGLYFGLYDSIKPVVLTGSLQGNFLASFALGWCVTTAAGIASYPLDTIRRRMMMTSGEAVKYKSSFDAGKQIIAKEGVKSLFKGAGANILRGVAGAGVLSIYDQLQVLLFGKAFKGGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLK9</accession>
    <name>E3QLK9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fic/DOC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_06722</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697357">
        <property type="protein sequence ID" value="EFQ31747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008097576.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLK9"/>
    <dbReference type="GeneID" id="24412087"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06722"/>
    <dbReference type="eggNOG" id="KOG3824">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066666_0_0_1"/>
    <dbReference type="OrthoDB" id="439046at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3290.10">
        <property type="entry name" value="Fido-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003812">
        <property type="entry name" value="Fido"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036597">
        <property type="entry name" value="Fido-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040198">
        <property type="entry name" value="Fido_containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13504:SF38">
        <property type="entry name" value="FIDO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13504">
        <property type="entry name" value="FIDO DOMAIN-CONTAINING PROTEIN DDB_G0283145"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02661">
        <property type="entry name" value="Fic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140931">
        <property type="entry name" value="Fic-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fido" evidence="3">
        <location>
            <begin position="125"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
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            <position position="218"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="222"/>
            <end position="229"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
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        <source>
            <dbReference type="PIRSR" id="PIRSR640198-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-2"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51459"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EFQ31747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="290" mass="32697" checksum="A6D1A87B7B4022DD" modified="2011-01-11" version="1">MGYKSLQQDYKGMLAEIDELRELMKPRIPELAKTLVAEYAHQSVSIEDNPLKIGDTIAVFDLLTSKLFAHVDIASIAAEDLAQLALPQLRSDGGDESVVNELKNHIVASQWIAESAAARLGTAGMDEAEMRQLAAMTIKGTESEAIYAMAWGGSVPLGGYRKLPIAVRSNPLEVFPYPAEVPACVNRFFNWRNSQHHSKEIHPLILACQMTAYFVHIHPFPDGNGRVSRMLMHDYMVRQGYLPVVMQNLERQDYLRMIKDACNGDPRELVITVLSTQLDELHTFYWRQRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
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    <name>E3QM54_COLGM</name>
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        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="2" type="ORF">GLRG_07086</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
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        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
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            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
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    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EFQ31942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008097771.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QM54"/>
    <dbReference type="STRING" id="645133.E3QM54"/>
    <dbReference type="GeneID" id="24412451"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07086"/>
    <dbReference type="eggNOG" id="ENOG502SKVR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="5309037at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42354">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42354:SF1">
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    </dbReference>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="186"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="360" mass="39661" checksum="1F8121312599C18A" modified="2011-01-11" version="1">MEPTTVIGAVSALVELFADGAEHYAEWKRKRALNNNYFRNPDSGVRRHVITCALSTSLDASANQIKETYDIGFTLLGAEFSLGDATCRDMLCNQLFNLGSRISHLRRASAHSGSTGFLNLPDIIQASESARLASVRALAELYFRVAGGRPDIPKCLPVPRPRPRQDRSISRYQASPAEENNGGGDNNNNEGGDETTTAMTMTTDQAPFQSEPPSPPPTPPAPKPISNDDVSLFTPSEAGASSTGTVHLRPKVSVFSMFCPEAMTFQVDLSKRIPETPKRCKCGYRWMPLLPNNKDFIVLKEGFRMSSRFLAKSHSDRNEFACCLCVPSGKTNKYESADALRAHINISHIKWQILHDRDIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMN8</accession>
    <name>E3QMN8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Calmodulin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_07270</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
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        <lineage>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EFQ32126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096146.1">
        <property type="nucleotide sequence ID" value="XM_008097955.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMN8"/>
    <dbReference type="STRING" id="645133.E3QMN8"/>
    <dbReference type="GeneID" id="24412635"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07270"/>
    <dbReference type="eggNOG" id="KOG0027">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061288_13_1_1"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071341">
        <property type="term" value="C:medial cortical node"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110085">
        <property type="term" value="C:mitotic actomyosin contractile ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016460">
        <property type="term" value="C:myosin II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903475">
        <property type="term" value="P:mitotic actomyosin contractile ring assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000003">
        <property type="entry name" value="Calmodulin A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="CALM/Myosin/TropC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF0">
        <property type="entry name" value="CALMODULIN LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="9"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="80"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00020786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ32126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="147" mass="16489" checksum="BD7A739C980F7C6B" modified="2011-01-11" version="1">MASNQYDAQASTNYKEAFSLFDKRGNGRVPVDSLGDLLRACGQNPTLTEIRDLEKNIGSDFDFETFQRILNRPGGFRDPGEPEEYCRGFQVFDKDMTGFIGVGQLKYILTNLGEKMTDEEVDELLKAVDTSSGQVNYTELVRTILAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNI6</accession>
    <name>E3QNI6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07743</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697362">
        <property type="protein sequence ID" value="EFQ32473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096493.1">
        <property type="nucleotide sequence ID" value="XM_008098302.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNI6"/>
    <dbReference type="STRING" id="645133.E3QNI6"/>
    <dbReference type="GeneID" id="24413108"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07743"/>
    <dbReference type="eggNOG" id="KOG0740">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004471_6_3_1"/>
    <dbReference type="OrthoDB" id="10042665at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19481">
        <property type="entry name" value="RecA-like_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054289">
        <property type="entry name" value="DUF7025"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411:SF3">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411">
        <property type="entry name" value="FAMILY ATPASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22942">
        <property type="entry name" value="DUF7025"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="1">
        <location>
            <begin position="492"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="715" mass="81148" checksum="E3DECC443A318904" modified="2011-01-11" version="1">MGITDVFDKEVLSEKAWKMRCRLLPHKEDVGRPIQDIEGSLSDEDLKKQPAKNPTFGVDATVKTLYEGKNSCGGVYDWVDFPPKQMSKKAAESQDRPAIKVYKIKDMDKPIIGGRFSLAYHQISIQNPTLVAALEPILKKEDFHIDPNDTATFEAPFRPLFFCYDDILDLYRTTDDSSLKGYLQLLVRTLDDVLGETREKKRKLQSSCLIHFKMAWTYFPRGSVVYSSACNTEMLCKVEGTAYERAEGTVVLNVNCKILTFNGETFVWSDHKLQIPKFAGNRPIRDLDHYPLQFHEDKEGMMRRTLARGTRVLDLQGLTYCTYTGVAVGEKSRYNVEGRILVDVVGFNKYERARGKREQDDANTRRNRVVSHEEIFFSNEGADATKDADPIKTETGGGRHLAAKKQQRNKEEMLAREDDLVFMSPLIEGFALKNKVWLAFYVEDIAPITWNDTAYDHLVYDEQQKDLVLSFVENHGRGGRSAMEDVIVGKGQGLIILLSGPPGTGKTLTAEAVADRTHRPLFYLQAEDLGINPSTLGEKVKRVFEMATEWDAVVLLDEADVFMAERNPNDIARNELVSIFLRELEYFRGIIFLTTNLYNTIDTAFRSRVSLHLLFKALSPDSRGLIWRKFLGRLPPAGGDEKADGLVPLSDEDIKELGQWQLNGREIKTAVKMVSKWCDHKGYEMSLARLENGIRVTSPHASKQKHAEDDDDLYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNW4</accession>
    <name>E3QNW4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07566</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697363">
        <property type="protein sequence ID" value="EFQ32552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096572.1">
        <property type="nucleotide sequence ID" value="XM_008098381.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNW4"/>
    <dbReference type="GeneID" id="24412931"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07566"/>
    <dbReference type="eggNOG" id="ENOG502R70B">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_174169_0_0_1"/>
    <dbReference type="OrthoDB" id="4850383at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="21"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="109" mass="12059" checksum="32384ACAC50493D4" modified="2011-01-11" version="1">MKLSLEQKNPLAKKVENTDSAKAAIQNNTNQTATTGESFSTGKSAAAAIAQHKKPRRVIRPRPQHATPLDTVDDDDYDDCWLPAYEDPQPTDRLVDDDWVSVKKPASAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNZ0</accession>
    <name>E3QNZ0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DASH complex subunit SPC19</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Outer kinetochore protein SPC19</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">GLRG_07592</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
            <location evidence="3">Centromere</location>
            <location evidence="3">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DASH complex SPC19 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697363">
        <property type="protein sequence ID" value="EFQ32578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096598.1">
        <property type="nucleotide sequence ID" value="XM_008098407.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNZ0"/>
    <dbReference type="STRING" id="645133.E3QNZ0"/>
    <dbReference type="GeneID" id="24412957"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07592"/>
    <dbReference type="eggNOG" id="ENOG502SDEQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112993_0_0_1"/>
    <dbReference type="OrthoDB" id="3361333at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042729">
        <property type="term" value="C:DASH complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005876">
        <property type="term" value="C:spindle microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008608">
        <property type="term" value="P:attachment of spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013251">
        <property type="entry name" value="DASH_Spc19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28262">
        <property type="entry name" value="DASH COMPLEX SUBUNIT SPC19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28262:SF1">
        <property type="entry name" value="DASH COMPLEX SUBUNIT SPC19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08287">
        <property type="entry name" value="DASH_Spc19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0137">Centromere</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="110"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="76"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="145"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EFQ32578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="180" mass="19679" checksum="7D6AAB1F3421CB9B" modified="2011-01-11" version="1">MAQNAATYADCVASLRSSLNFLESSVATLDAGVSDLPRLSSVLRPTRHFELIPQPTLAAAEASLRDEIGPQIALLLDRAEAQIARRERRIETLQARCELLQGRLAQPEGDEYGGYGGAGKKGKSKGLGRGAGTKRPLGGESALRARAVRQRREGLEYSVERLELEVLTKERELRKRLDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPN0</accession>
    <name>E3QPN0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_07951</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697365">
        <property type="protein sequence ID" value="EFQ32807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096827.1">
        <property type="nucleotide sequence ID" value="XM_008098636.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPN0"/>
    <dbReference type="STRING" id="645133.E3QPN0"/>
    <dbReference type="GeneID" id="24413316"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07951"/>
    <dbReference type="eggNOG" id="KOG1577">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_0_1_1"/>
    <dbReference type="OrthoDB" id="416253at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd19071">
        <property type="entry name" value="AKR_AKR1-5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000002">
        <property type="entry name" value="2,5-diketo-D-gluconic acid reductase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="2,5-DIKETO-D-GLUCONIC ACID REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827:SF13">
        <property type="entry name" value="ALDO_KETO REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="5">
        <location>
            <begin position="30"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="4">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ32807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="288" mass="32051" checksum="8F0C1A96E3929B24" modified="2011-01-11" version="1">MAPSKYTLATRLTLANGKTIPQIQLGLYMMSGREVTKAVPWALAAGYRGFDCAQMYRNEREAGKAIRDFLASGENSQGLTREDIFYTTKLASNSTSYDAVRKSIKQSVDVSGLGYVDLFLLHSPYGGKEARLTSWRAVEDAIDAGEVKMGGVSNYGVAHIEELMVSKPRVAPVINQIEVHPFNTQTHIRETCAKHDIAIEAYAPLARGMRMKHPKILELSKKYGCTPAQLFVRWSLDHNMITLPKSVRRDRLIENADVSGFDISKEDLAAMDALDEHLVTDWDPTETP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPW9</accession>
    <name>E3QPW9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Succinate-semialdehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_08040</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; 4-aminobutanoate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697365">
        <property type="protein sequence ID" value="EFQ32896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096916.1">
        <property type="nucleotide sequence ID" value="XM_008098725.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPW9"/>
    <dbReference type="STRING" id="645133.E3QPW9"/>
    <dbReference type="GeneID" id="24413405"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08040"/>
    <dbReference type="eggNOG" id="KOG2451">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_5_3_1"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004777">
        <property type="term" value="F:succinate-semialdehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009450">
        <property type="term" value="P:gamma-aminobutyric acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07103">
        <property type="entry name" value="ALDH_F5_SSADH_GabD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000023">
        <property type="entry name" value="Succinate-semialdehyde dehydrogenase (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000004">
        <property type="entry name" value="Succinate-semialdehyde dehydrogenase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050740">
        <property type="entry name" value="Aldehyde_DH_Superfamily"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353:SF7">
        <property type="entry name" value="SUCCINATE SEMIALDEHYDE DEHYDROGENASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353">
        <property type="entry name" value="SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="4">
        <location>
            <begin position="25"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ32896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="500" mass="54486" checksum="569A4EFDA88358E2" modified="2011-01-11" version="1">MSADLPFKLANDDLLKTDAYVHGSWVTSSSKKRFDIEDPGTGKVFASSPDFDRSDVDAVVKSAHEAFQTYRLENPRSRAKKLLEWDRLIRENREDIALVLTHESGKPLAEAQGELDYALGFTWWFAGEAERIRGDVSTPSAPNRRVLIIKQPIGVAVALVPWNFPIAMILRKAGAALAAGCTMIAKPSPETPLTCLILANLASKAGFGPGVFNVITTSLENTPEVAEALCKHPLTKKVSFTGSTNIGSLIAKHCAEGLKKLTLELGGNCPFIIFDDCNQDQALEQLLALKWRHAGQACITANRVYVQDGIYEHFLEKLVERTKKIKMGHGSESGTTMGPLTTPRAIPKAQAHVKDAVEAGAKVVHGGRAGAEAGLAAGYFHEPTILRDMKQSMLISREETFAPVLGVYRFSTEDEAVQWANDTSMGLASYFFTKNIDRTWRLMEKLEAGMIGMNTGNSSAAESPFGGMKLSGYGKESGKDVAIEEYLVSKTVTMTLEGHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQN4</accession>
    <name>E3QQN4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase inhibitor I9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_08316</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protease inhibitor I9 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697368">
        <property type="protein sequence ID" value="EFQ33172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097192.1">
        <property type="nucleotide sequence ID" value="XM_008099001.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQN4"/>
    <dbReference type="STRING" id="645133.E3QQN4"/>
    <dbReference type="GeneID" id="24413681"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08316"/>
    <dbReference type="eggNOG" id="ENOG502SBW1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_156026_3_1_1"/>
    <dbReference type="OrthoDB" id="5518345at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004866">
        <property type="term" value="F:endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042144">
        <property type="term" value="P:vacuole fusion, non-autophagic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.80:FF:000005">
        <property type="entry name" value="Proteinase inhibitor I2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="entry name" value="Peptidase S8 propeptide/proteinase inhibitor I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052471">
        <property type="entry name" value="PBI_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28288">
        <property type="entry name" value="PROTEASE B INHIBITOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28288:SF2">
        <property type="entry name" value="PROTEASE B INHIBITOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inhibitor I9" evidence="2">
        <location>
            <begin position="3"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ33172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="71" mass="7968" checksum="767DF0BA256B4687" modified="2011-01-11" version="1">MPTYIVTCKEDASAEQVQAAKKHATDQGGKIGHEYSLIKGFSVEFPEDQISTLESHEHVKHVEKDQEVKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QR77</accession>
    <name>E3QR77_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08644</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697370">
        <property type="protein sequence ID" value="EFQ33365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097385.1">
        <property type="nucleotide sequence ID" value="XM_008099194.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QR77"/>
    <dbReference type="STRING" id="645133.E3QR77"/>
    <dbReference type="GeneID" id="24414009"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08644"/>
    <dbReference type="eggNOG" id="ENOG502S29P">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053544_0_0_1"/>
    <dbReference type="OrthoDB" id="5329385at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018790">
        <property type="entry name" value="DUF2358"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031342">
        <property type="entry name" value="Mug163-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31094">
        <property type="entry name" value="RIKEN CDNA 2310061I04 GENE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31094:SF2">
        <property type="entry name" value="RIKEN CDNA 2310061I04 GENE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17119">
        <property type="entry name" value="MMU163"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ33365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="303" mass="31563" checksum="672CBE60CDF7EDE5" modified="2011-01-11" version="1">MAAVRLTTSPGVRSAAASPLTSQLWSSATANAATARTSVPAAAAAAAVVASTPLSPLFVPTRDGTKHRDASNRYFNPSNTVLSGNGGSPGKKPGDENKANLGKTLRILQDHLPSVLQSPLPQEILAPNISLHLFPTTHPHLPTVSGRVAYTAALWTSPIAWNRLPLVGNVRLSIMSERVTKHPIHFAPLRPGAIPEQLVVRWCATSKKNGSTTAAAAAAAAATTTTTTTTTGGGDKAFTGLFVFQFDAEGRILSHTIETVQEGGEWEKGVGAKVVGLTDWLLGGMRRQGDSPSPAFEGLGKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRA1</accession>
    <name>E3QRA1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Fungal specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_08668</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697370">
        <property type="protein sequence ID" value="EFQ33389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097409.1">
        <property type="nucleotide sequence ID" value="XM_008099218.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRA1"/>
    <dbReference type="STRING" id="645133.E3QRA1"/>
    <dbReference type="GeneID" id="24414033"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08668"/>
    <dbReference type="eggNOG" id="ENOG502QQCV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013838_0_0_1"/>
    <dbReference type="OrthoDB" id="10263753at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF87">
        <property type="entry name" value="COL-21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="54"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="82"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="387"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="614"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="18"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="92"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="619"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="657"/>
            <end position="678"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ33389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="759" mass="84515" checksum="4D5849D5F7C9E145" modified="2011-01-11" version="1">MADDRRDSSEKPSSARESLNSNSNPSPTPTQNQPHKQTQDARPPPKKRRRVVISCTECHRRKQKCDRDLPCANCKSRNKQDACKYETGAPTAKEHRKAEAEGAKPTSTQSLSNAAANWGYSHAGASTLGLMRKIESANGDGALSHLGGSAHIEDQFATKERYKSLIRQLPAKGYIEKLIDVYFREFNHQYYALEEDLFKEQFAEWNNIPFNVLSNSGPQGLSPDLRVFPALLFQVLATALLTLPEGSHEFYEHLKYAGNMTFEDLAADYSESGVGILSLLGKRQITLTTVQADFLRAAFLKYMAKVTESWHAIGNAIRDAQEIGMHRDSLDPSPNGDDTGDILENMWLIQRRRKLYMVLMTWDIHCALVLGRPGSIDWRICPPSLPVDTPPPKDRRKTPVAPRDDERDPPTPLTRVIWAFRLVAPMREILELEQDGPCPKDYSKVYRVHQMCLDLDEATPAYFRLENPDTKWDNDPSCYWLQSVRFYLPQMNLFNLMALHRPYIFNRQKSRTEALKASIEMLHRQMLTFQGLDAGSWRNFTLFFGSFDAVVLMASIYILFPKENLEMAGSAMQHFHWTTERFEAMQERNPLAKAAKGVLQAIFAKFKKAVGNPAPPPSLSSVASQTPASTSDSGSSLSARGSVSTATAATADTPASKGSTAATPTSLPTVPDTSSSYPLPSAHSEWTMPNSWDFTSIAPLFPMGDLIYHDLNGIPEDGSLPAWGAATPPLPAAGTTTFEGDFGNDSVWNLLNQYDPTSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRC5</accession>
    <name>E3QRC5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08692</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697370">
        <property type="protein sequence ID" value="EFQ33413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097433.1">
        <property type="nucleotide sequence ID" value="XM_008099242.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRC5"/>
    <dbReference type="STRING" id="645133.E3QRC5"/>
    <dbReference type="GeneID" id="24414057"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08692"/>
    <dbReference type="eggNOG" id="ENOG502S84A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093522_0_0_1"/>
    <dbReference type="OrthoDB" id="4590138at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39474:SF1">
        <property type="entry name" value="FUNGAL SPECIFIC TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39474">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="78"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ33413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="182" mass="18869" checksum="75082EE2AF7DD937" modified="2011-01-11" version="1">MATEEASWSTNGLAATAGSAAGGRQGGQNREVEDGSHREHHQTQSTSLAPENTTSPAPAADISNTDSSQQQPQVQGAAEPAQQKQPLALPPLPEPPSEGNSAGGNGIVTLDMSGGEGASTKLDHLGPLVVNQDGTMSRISNWGEMTEIERRNTLRILGKRNQIRLAGLRGEGNGTEDGADRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSJ8</accession>
    <name>E3QSJ8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_08980</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697374">
        <property type="protein sequence ID" value="EFQ33836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097856.1">
        <property type="nucleotide sequence ID" value="XM_008099665.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSJ8"/>
    <dbReference type="STRING" id="645133.E3QSJ8"/>
    <dbReference type="GeneID" id="24414345"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08980"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_0_1"/>
    <dbReference type="OrthoDB" id="47007at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24321">
        <property type="entry name" value="DEHYDROGENASES, SHORT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24321:SF8">
        <property type="entry name" value="ESTRADIOL 17-BETA-DEHYDROGENASE 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ33836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="271" mass="28899" checksum="C57D242512750B60" modified="2011-01-11" version="1">MSAPSAIYPSLNGKTVLITGGAEGIGAATVERFALQGCQVIFLDIAGTLAQKTIQHVMSIASETGASLNTIKTPVFYFCDVSNLGQLQATANEILETYGTVHVLINNAALTGHKARLRTEEVTSEAWDMNINTSLRHVFFLTQAVLPGMKQAGGGSIVNLGSITWRIPDPAVPVYGTCKAAVMGLTRAQSKEVGPLNIRINSVMPGAIATQRQRDEVLTPEYRAEVMRSQSLQRDLMPEDVAKLIVFLASDEASGITGSSYVVDGGWCSDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSM3</accession>
    <name>E3QSM3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chitinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09005</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697374">
        <property type="protein sequence ID" value="EFQ33861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097881.1">
        <property type="nucleotide sequence ID" value="XM_008099690.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSM3"/>
    <dbReference type="STRING" id="645133.E3QSM3"/>
    <dbReference type="GeneID" id="24414370"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09005"/>
    <dbReference type="eggNOG" id="KOG2806">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_519717_0_0_1"/>
    <dbReference type="OrthoDB" id="73875at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF333">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH18" evidence="1">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ33861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="524" mass="57829" checksum="B0C0D3609DEA58F7" modified="2011-01-11" version="1">MLLEEIPFGYYTDIIFSFATMDPKTIEIQAGDSKTAQFMQRINAIKLIQSDIKIRIAVGGWAFNDPGPTQTTFGDMAASTSATKSFIDSLIKMMNKNSGVCMPGCNDDEVKVGSLRVGCNFSHQAACCTSEESTSAYGSCKWVGEAPTCNQDCPSDYPNKIFSSKMAAGGEQPCISGTKHYCCREPKPAAFSKCDWHNKASPRRFEQDFICEDSCPSGQIKLATEVGGMGASNGCFGGARAYCCEPPPKPVVPRGDDDPFGGTQNKEFQLLLEKYMEYPPCPATILRPKLGDMFTNVKRSLEFEASQARDLQGRATNCEMDRYVRMVGFGVALLTKESDLIGPLQPVYDEIFAGAYDEAITAEKLRAHYQRNPELDPNAVMQYVFLNPKAAGPGLRRAAQASETFCWLPTTRKRDGKALSETSRHPSDVGKRWVWWLPNDENGTPDISTILGGILNGDLSLHYARWQNLSQQNVPMLELGYWIGRTPGAAGGNDMYRDPYMADGGPQDRWVVFHMHIDEAPCLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSM9</accession>
    <name>E3QSM9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="8">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_09011</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="8"/>
    <dbReference type="EMBL" id="GG697374">
        <property type="protein sequence ID" value="EFQ33867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097887.1">
        <property type="nucleotide sequence ID" value="XM_008099696.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSM9"/>
    <dbReference type="STRING" id="645133.E3QSM9"/>
    <dbReference type="ESTHER" id="colgm-e3qsm9">
        <property type="family name" value="Fungal_carboxylesterase_lipase"/>
    </dbReference>
    <dbReference type="GeneID" id="24414376"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09011"/>
    <dbReference type="eggNOG" id="KOG4389">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006586_10_6_1"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000213">
        <property type="entry name" value="Carboxylic ester hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005127990" description="Carboxylic ester hydrolase" evidence="8">
        <location>
            <begin position="18"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="9">
        <location>
            <begin position="28"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ33867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="582" mass="63319" checksum="16209B3DA642ABF1" modified="2011-01-11" version="1">MIFLTLVLVSLFTLACGVPWKRDGGTPQVTIKSPQANLKGTTKGILGLHDGEVESFMGIPYAKPPLGDLRFKPPVRLTEALGDFDATNDQPEACPQFAIPPDFGSPLIPPDLLDTVLSLPIIQNLAVGQEDCLTINVQRPAGTKEGDKLPVMYWIFGGGFELGSTSMYNGVGLVAEGVQIGKPFIFVAVNYRVGGFGFMPGKDLMEEGSSNAGLLDQRMGLEWVQDNIASFGGDPDKVTLWGESAGAISIFSQLTLFNGNITRNGKQLFRGAIMNSGSAVPTDPMDCPKATKVYEQVLSAAGCSGAQDRLKCLRALSYDDMRKAANSVPALLSYTSVALSYLPRPDGTNIPSSAEVFATSGKLPKVPFILGDQEDEGTLFALFQPNITTTDDVETYLSTLYFNNASPEQVQNLVATYSPLPFDGSPFGTSIFNEVRPQFKRLAAILGDAVFTLTRRAVFNIFQQVQPQVNTWSYLASYDYGTPVLGTFHGSDLLQVFFGIKPNYARAATRAYYFNFAYNLDPNDCSGGSGKCTPNADLINWPKWRDGNMLLHMGADSADLIADDFRQESFNFLINNIEKLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSR3</accession>
    <name>E3QSR3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Nicotinamide-nucleotide adenylyltransferase</fullName>
            <ecNumber evidence="8">2.7.7.1</ecNumber>
            <ecNumber evidence="8">2.7.7.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_09045</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>beta-nicotinamide D-ribonucleotide + ATP + H(+) = diphosphate + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:21360"/>
            <dbReference type="ChEBI" id="CHEBI:14649"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="EC" id="2.7.7.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>nicotinate beta-D-ribonucleotide + ATP + H(+) = deamido-NAD(+) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22860"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57502"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="EC" id="2.7.7.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from nicotinamide D-ribonucleotide: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the eukaryotic NMN adenylyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.1" evidence="8"/>
    <dbReference type="EC" id="2.7.7.18" evidence="8"/>
    <dbReference type="EMBL" id="GG697374">
        <property type="protein sequence ID" value="EFQ33901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097921.1">
        <property type="nucleotide sequence ID" value="XM_008099730.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSR3"/>
    <dbReference type="STRING" id="645133.E3QSR3"/>
    <dbReference type="GeneID" id="24414410"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09045"/>
    <dbReference type="eggNOG" id="KOG3199">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033366_0_1_1"/>
    <dbReference type="OrthoDB" id="422187at2759"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000309">
        <property type="term" value="F:nicotinamide-nucleotide adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004515">
        <property type="term" value="F:nicotinate-nucleotide adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD+ biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051182">
        <property type="entry name" value="Euk_NMN_adenylyltrnsfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005248">
        <property type="entry name" value="NadD/NMNAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00482">
        <property type="entry name" value="nicotinate (nicotinamide) nucleotide adenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12039">
        <property type="entry name" value="NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12039:SF0">
        <property type="entry name" value="NICOTINAMIDE-NUCLEOTIDE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0520">NAD</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 8 10" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="1 8" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cytidyltransferase-like" evidence="9">
        <location>
            <begin position="38"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ33901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="264" mass="29794" checksum="D9906D1BF5A7ED0A" modified="2011-01-11" version="1">MVASPETIEAMTPPGYTFPDHRLRLQQSEPDREPLVLVAPGSYSPITFLHLRMAVMAADYVRYNTNFELIGSYMSPVSDAYKKRGLAPACHRRRMCEIAAEQTSRFLMVDPWEAEQTAYVPTAVVLDHFEYEINVKRGGCNGKRVKIAVLAGADLINTMSQPGVWSPSDLRHILGDFGAFVLERAGVNIDEALGNLKEYEDQIYYIPQVVPNDVSSTKIRLLLRRNMSIDYLIPAEVIKYIDEHGLYHEDDAATNEKGKEKEVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSV6</accession>
    <name>E3QSV6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">2OG-Fe(II) oxygenase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_09088</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697375">
        <property type="protein sequence ID" value="EFQ33944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097964.1">
        <property type="nucleotide sequence ID" value="XM_008099773.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSV6"/>
    <dbReference type="STRING" id="645133.E3QSV6"/>
    <dbReference type="GeneID" id="24414453"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09088"/>
    <dbReference type="eggNOG" id="KOG0143">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010119_4_0_1"/>
    <dbReference type="OrthoDB" id="288590at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044283">
        <property type="term" value="P:small molecule biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="3">
        <location>
            <begin position="184"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ33944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="373" mass="41674" checksum="37713C0679A12F7C" modified="2011-01-11" version="1">MGVSTEVPQTVEWAGKRVPIYPMETVDFGRVLSQEPAELEIMLRCCQEQGFFYLDLNGLDGSRFLDDQQKTLELMHRYFESPIEAKNEFGLITAHLGYEPVGSRTGGLPNTRDGYEMFKVSRDEIQRKDPKFPQILQNDTDKGILKNAISGSNIVTKAVLSGLSSAMGLVGAARYENAHRNDRPSTSTLAMMHYVPADPVKDKEIGHQKHTDISSLTLLFAEEWGLQIRPPGTKEFGFVAPKKGCAIINVGDSLRFASGHTMMSCIHRVVPFNPEEHRYSIAYFLRAENETMFTDSEGRYVTAGQWHDEKFFLFKATPDIQALAPPSMLYGGMTADEEWTPYAQPVAKAHESEVPVDGPKQAPVVKETLVEAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTF9</accession>
    <name>E3QTF9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_09291</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697377">
        <property type="protein sequence ID" value="EFQ34147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098167.1">
        <property type="nucleotide sequence ID" value="XM_008099976.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTF9"/>
    <dbReference type="GeneID" id="24414656"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09291"/>
    <dbReference type="eggNOG" id="ENOG502SHH0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082769_0_0_1"/>
    <dbReference type="OrthoDB" id="5190067at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ34147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="256" mass="29182" checksum="AB2CD58F1B6971EC" modified="2011-01-11" version="1">MKAPLEQQQEIENGILIQVLHRSGSSIAMCRLCPRPGCSVIPPRIVQPAPSYDGASAFAAYQVFKDTPEDLEAAVRPLRPPFGIVIYDMMHTARPTLSARLTRTVFDRTCRYHRHRNYRPDRVEVVTPPLLQSSTDVEHVDACICHHDEEIQSRTLILNEAEPVSWFLPRRDLNGSYARRILAINRLEGYSSDDEVEVALGKEPLSNKEDALEHAALKNSEASRSGSFLGIDWQPRKELWSLYNGRNYDPDMEMRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTR8</accession>
    <name>E3QTR8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_09374</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697378">
        <property type="protein sequence ID" value="EFQ34230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098250.1">
        <property type="nucleotide sequence ID" value="XM_008100059.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTR8"/>
    <dbReference type="STRING" id="645133.E3QTR8"/>
    <dbReference type="GeneID" id="24414739"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09374"/>
    <dbReference type="eggNOG" id="ENOG502T4KZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1686445_0_0_1"/>
    <dbReference type="OrthoDB" id="4851677at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="137"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ34230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="171" mass="17728" checksum="E2B2E25FFBFCF564" modified="2011-01-11" version="1">MSSPGSSSASLTDLIRDALVEVYNSSPAGWHEFECASLDALAKMSNEIAKAAAAMEEDVNMPDADADGDGDGDVESRDDDVESRDDDDDDDDDDDDDGDDEDSGGGSGSGSTPGPSGSGGSGQRGKGGGRGGRVFHCPFAGCGKSYTVAWTRTRHIKEKHPDQPVPPFNDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QU64</accession>
    <name>E3QU64_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="5">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_09546</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the tannase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="GG697379">
        <property type="protein sequence ID" value="EFQ34402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098422.1">
        <property type="nucleotide sequence ID" value="XM_008100231.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QU64"/>
    <dbReference type="GeneID" id="24414911"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09546"/>
    <dbReference type="eggNOG" id="ENOG502QPXZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014819_1_1_1"/>
    <dbReference type="OrthoDB" id="3039123at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011118">
        <property type="entry name" value="Tannase/feruloyl_esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938:SF2">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938">
        <property type="entry name" value="FERULOYL ESTERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07519">
        <property type="entry name" value="Tannase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005127992" description="Carboxylic ester hydrolase" evidence="5">
        <location>
            <begin position="22"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ34402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="520" mass="56268" checksum="777AB7E043370F99" modified="2011-01-11" version="1">MPFAPSLLGLVLWVATHGVQGLSLSTRCSVEGINSFLAEDDMAEVLVAYSISSNGSFGEAGNVAYPQNATHLPSLCAATINITSSSTSSYTFGVFLPDEWNKRFLAVGNGGFSGDINWYAMGTGAKYGFATISTSTGHNSTSQDMSWALNNPETKADWAGRSLHGSTILAKAIVAGYYGNAARKSYYSGCSTKGRQGVKSAQDHPEDFDGILAGAPAGMSTSQQLWQLKVGAINLPVDGPGYLPNALFEVIGQEVLRQYDGSDGVDDGVIMDPKHCNFRPEKLLCTSSPVNRSACLTAPQVSTLKQLYLPLIQLDADVNNLTYIYPNFGLGSEVQMLSSFGPNNEPSLYGTDYAKNYLFDDLDWDWKVNFNYSTFVEATKRNPGNVNANNFNLSTFHGRGGKLVQYHGYADGLIPTDVSRVLYDETWMAMAEQGIDLDDFYRLFLVPGMQHCSGSMYDAPWYFGASEHSSNLEANGQHVFPVPGLDDPQHDALLALVSWVEGGKGVNELVATKYANDTVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUC6</accession>
    <name>E3QUC6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_09608</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family. Isoflavone reductase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697380">
        <property type="protein sequence ID" value="EFQ34464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098484.1">
        <property type="nucleotide sequence ID" value="XM_008100293.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUC6"/>
    <dbReference type="GeneID" id="24414973"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09608"/>
    <dbReference type="eggNOG" id="ENOG502SPAG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044876_3_0_1"/>
    <dbReference type="OrthoDB" id="9984533at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF9">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="4">
        <location>
            <begin position="11"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ34464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="306" mass="33310" checksum="47B1A2BD7955E837" modified="2011-01-11" version="1">MHPIKKVAILGGTGALGEALVPALLKAGFEVTCVSRPGSKAAVFPGVVVKTADYTDVAALTEAFSNHDAVVEAFNPAGATHQARILKAILAAGVRHITTPDFSGNTFHPNAKDIFIFNPKLAAQQELERVVAESDGKLTWTAIVTGPWYDWTIEKGIFWINKANRTITRYGSGDQKCSMSRHALNGEALVAVLSDHENYRNRPAYFASHTVSTNQLISTVHKLGFTGWEVLDVPFDGFESRARAIWQKDTEMGVEDRLNSKAYAALSTVALLDEDNRYGSDFGDKVEPGWGESEVALMDNLKKSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUP0</accession>
    <name>E3QUP0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">O-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_09722</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697381">
        <property type="protein sequence ID" value="EFQ34578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098598.1">
        <property type="nucleotide sequence ID" value="XM_008100407.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUP0"/>
    <dbReference type="GeneID" id="24415087"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09722"/>
    <dbReference type="eggNOG" id="KOG3178">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005533_5_2_1"/>
    <dbReference type="OrthoDB" id="1535081at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712:SF16">
        <property type="entry name" value="O-METHYLTRANSFERASE ELCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="4">
        <location>
            <begin position="183"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ34578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="415" mass="46393" checksum="E8EA5959985E8CDF" modified="2011-01-11" version="1">MTGDHGNSVLEEAATATEEVNAAFRSFAAEPGPSGGDLDKAQRRRIIEAATKLINAVKDPADEWFDTTAQVAELGAKRLFAEWKVYDRIPLEGSISYGELAAKVDAEEALIRRIGGVLTSVNFLEQVGDDSVAHTKRSRVYANEHPIGLIFGMAWDNGLVPYVRLPAYFEKYGRKEPQTINQIPATYAYGVPEYSFYEMLQHDPPRLQRFLRAMGPIEEKMPIAGIYDFGWVVEYAEAHPSSDRPLFVDVGAGRGQSIKAIHGENPGLPLDKCVLQDRPEVVEAVEKLDDEDMRLVQKQVMDFHKEQPVKGALTYWIRRCLHNYGDEVSVNMLRIIAEAMTSDSRLLIQEDVAANPPHWTTTMLDFMMLTFGGKHRTLECWTDVLGRAGLKINSVSMGKGPWRHLAVIECVKASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QV88</accession>
    <name>E3QV88_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_09920</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697384">
        <property type="protein sequence ID" value="EFQ34776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098796.1">
        <property type="nucleotide sequence ID" value="XM_008100605.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QV88"/>
    <dbReference type="STRING" id="645133.E3QV88"/>
    <dbReference type="GeneID" id="24415285"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09920"/>
    <dbReference type="eggNOG" id="ENOG502SJ3M">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018354_0_1_1"/>
    <dbReference type="OrthoDB" id="9996127at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF9">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ34776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="376" mass="41325" checksum="88A00884F9EEB0A4" modified="2011-01-11" version="1">MDSGIEIYINQLSGVEVSEDGKTAKIGGGTGSKLVTDTLWEAGKQTVTGTCECVSTLGPALGGGHGWLQGHHGLVSDQFVSMNILLADGTLPTIDETSDLWWAVKGAGHNFGIVTSVDVKIYDIEHRDWAVETLIFSGDKNGTQAADVVNWSYWLNNPDAGPENVTYHFVLDHSRGCYDSRPAYTQPFRDIGPISSTTESGTYLDLAAWTFIALDSIPCQKSGLNNPRFPIYVESYNIEAQRKAYDLFASSIRGDLPFTNSLFMFEGYSVQGVKAIESDSTAFAYRGDNLLFAPLITYTPGGAELDEQAAALGNQLRDIIHEGSGRTDQHVYLNYAFGNESPKEWYGSEEWRQDRLKSLKTKYDPNGRFSFYGPIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QV97</accession>
    <name>E3QV97_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Cutinase</fullName>
            <ecNumber evidence="3 12">3.1.1.74</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_09929</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants. Degrades cutin, a macromolecule that forms the structure of the plant cuticle.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 12">
            <text>cutin + H2O = cutin monomers.</text>
            <dbReference type="EC" id="3.1.1.74"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the cutinase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.74" evidence="3 12"/>
    <dbReference type="EMBL" id="GG697384">
        <property type="protein sequence ID" value="EFQ34785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098805.1">
        <property type="nucleotide sequence ID" value="XM_008100614.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QV97"/>
    <dbReference type="ESTHER" id="colgm-e3qv97">
        <property type="family name" value="Cutinase"/>
    </dbReference>
    <dbReference type="GeneID" id="24415294"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09929"/>
    <dbReference type="eggNOG" id="ENOG502S3AW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040058_2_2_1"/>
    <dbReference type="OrthoDB" id="2975078at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050525">
        <property type="term" value="F:cutinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000675">
        <property type="entry name" value="Cutinase/axe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043580">
        <property type="entry name" value="CUTINASE_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043579">
        <property type="entry name" value="CUTINASE_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011150">
        <property type="entry name" value="Cutinase_monf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48250:SF1">
        <property type="entry name" value="CUTINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48250">
        <property type="entry name" value="CUTINASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01083">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00129">
        <property type="entry name" value="CUTINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01110">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00155">
        <property type="entry name" value="CUTINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00931">
        <property type="entry name" value="CUTINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 12" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="6 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005127953" description="Cutinase" evidence="12">
        <location>
            <begin position="19"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="10">
        <location>
            <position position="192"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="42"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="175"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR611150-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR611150-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ34785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="217" mass="21981" checksum="E5D5F964B7188021" modified="2011-01-11" version="1">MHRSTPALLLAVLGMASASPFAIVPRQADFSGNQQDGLSGPCQPTMVIFARGTTERGNVGTLAGPPFFQALSAQVGGALAVQGVEYPASVQGFLAGGDAKGSQTMATLTEQAITKCPNSSIIMSGYSQGGQLVHNAAAMMSQSMVASVAGAVIFGDPLNGQPVQGVPTQRTMVICHNGDNICEGGSQIRRAHLTYGDNAAEAAQFAASMTPPSAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVJ0</accession>
    <name>E3QVJ0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transmembrane amino acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_10022</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697385">
        <property type="protein sequence ID" value="EFQ34878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098898.1">
        <property type="nucleotide sequence ID" value="XM_008100707.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVJ0"/>
    <dbReference type="STRING" id="645133.E3QVJ0"/>
    <dbReference type="GeneID" id="24415387"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10022"/>
    <dbReference type="eggNOG" id="ENOG502QURM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016053_1_0_1"/>
    <dbReference type="OrthoDB" id="40134at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48017">
        <property type="entry name" value="OS05G0424000 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="323"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="353"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="391"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="441"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="467"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="537"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="8">
        <location>
            <begin position="112"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="59"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ34878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="577" mass="62562" checksum="46BDFFDD1FD0AF9D" modified="2011-01-11" version="1">MEEAAVNLHDPNVTFEEYLYWASVTRAEESLANERFLQAQGPLTLKRVIKDRFRKGDEHEVFQSEGGNAGAGNGEKAGGDSDKALQPAREGDGGAVTPEEWKRASRAMRTAGWGAIFYLITTDILGPFSTPWAFAQMGYGPGIALFTVFGVMSFYSGWLLYKSFLGLDSDRYPLKGYGDLYFRVFGAAARHAVNFAQALQLLLFVGVLILANGQSISQISKGPNGGAGICFVACLVIFVAAGFVLGQVRTLQRFSWAANVAVWFNLLIIFICMGVVAHSPPNFAATQASFGDAFGPGPVVTYAGTPPPGKASGGSGFLGSMNGLNQAVYSYGGCLIFAAFMAEMRHPMDFWKALLCGEVFIYLCYLIFGLYVYSYQGQYAFNPVMQGLSPYWWQTATNILGLVTGLIAAGLYGNIGMKVLYVELLQDVFGAPPLTETAGKALWAVAIPVYWALAFLVGAAVPQFSLVSGFIGALFILSFTYTLPALLGLGFWIRKDAMVPEEETFDPATGRYVYIDGGFRRYWRGFMKRPVFNTWNAVYMLGGLVTTALGMYSSIEGLIEAFNGKSQATSFGCSSPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVJ3</accession>
    <name>E3QVJ3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">P-type Na(+) transporter</fullName>
            <ecNumber evidence="19">7.2.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">GLRG_10025</name>
    </gene>
    <organism evidence="26">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="26" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="26">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>K(+)(in) + ATP + H2O = K(+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:75815"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>Na(+)(in) + ATP + H2O = Na(+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.3"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="21">
            <dbReference type="Rhea" id="RHEA:14634"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="18">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IID subfamily.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.3" evidence="19"/>
    <dbReference type="EMBL" id="GG697385">
        <property type="protein sequence ID" value="EFQ34881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098901.1">
        <property type="nucleotide sequence ID" value="XM_008100710.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVJ3"/>
    <dbReference type="STRING" id="645133.E3QVJ3"/>
    <dbReference type="GeneID" id="24415390"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10025"/>
    <dbReference type="eggNOG" id="KOG0202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002360_3_0_1"/>
    <dbReference type="OrthoDB" id="3352408at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008554">
        <property type="term" value="F:P-type sodium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02086">
        <property type="entry name" value="P-type_ATPase_Na_ENA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000001">
        <property type="entry name" value="Phospholipid-transporting ATPase IC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000015">
        <property type="entry name" value="Sodium ion P-type ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000020">
        <property type="entry name" value="Sodium ion P-type ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000039">
        <property type="entry name" value="Sodium P-type ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000047">
        <property type="entry name" value="Sodium P-type ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006414">
        <property type="entry name" value="P-type_ATPase_IID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01523">
        <property type="entry name" value="ATPase-IID_K-Na"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="15" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="16 23" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0915">Sodium</keyword>
    <keyword evidence="17" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="12" id="KW-1278">Translocase</keyword>
    <keyword evidence="6 23" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 23" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="302"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="329"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="800"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="837"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="878"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="925"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="976"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="1008"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="24">
        <location>
            <begin position="26"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="1070"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="22">
        <location>
            <begin position="1078"/>
            <end position="1088"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00035017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00035029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00049499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="EFQ34881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1097" mass="120601" checksum="AF8A18210955EC7A" modified="2011-01-11" version="1">MGKKDPEAEAMANHVSGQSNKPISRPAHALTAEQVIRELRANPDDGLTPQDAKTRLDEFGRNEFGEEAGVQPLKIFIGQIANAMTLVLILAMGASFGIGSWIEGGVVAGVILLNITVGFHQEFKAAKTMDSLRSLSSPTAQAVREGRNITVPTIEIVPGDMVELKTGDTIPADVRIIEAVNFETNEALLTGESLPIRKEAAQTYDDETGPGDRLNVAYSSSTVTKGRARGIVFATGMYTEIGQIAAALRGKNSRRRDVKRKEDGSASFGRYLQAWTLTLSDAVGRFLGVNVGTPLQRKLSKLAILLFGIAVVCAIIVLGANEFNTTQEVIIYAVATGLSMIPASLVVVLTITMAAGTKRMVQRHVIVRQLKSLEALGGVTNICSDKTGTLTQGKMVVRKAWIPGKGTFSISSTNEPFNPTVGDLGHSVDQPKDIDFRTKGGDGEPLSNADAEDRVKSCTVLTDYFNVASLANLANVHKTTEGEWHARGDPTEIAIQVFASRFNWNRLRLAGEANRWKQIAEFPFDSDVKKMSVIFEDRETKVEGGNKTWLFTKGAVERVISSCPTIQMGDQVVELNSDIEKDILSNMEALARLGLRVLAFASKPDIGVVDAHENLDRANYERDLTFRGLIGLYDPPRPESAPSVKKFHEAGVSVHMLTGDHPETARAIALEVGILPTRMNEISADVAKAMVMAAHDFDKLTDDDIDKLPHLPLVVARCAPQTKVRMIEALHRRQRFVAMTGDGVNDSPSLKRADVGIAMGESGSDVAKEASDIILTDDNFASILNAVEEGRRMFDNIQKFVLHVLACNVAQACTLLIGLIFKDDSGLSVFPLAPVEVMWIIMITSGLPDMALGFEVAAPDIMDRPPQNMKVGVFTWELMLDMLVYGLWTAALCLASFVLVMFGWGDGQFGSNCNNTYSQECDTVFRARATCFASLTWFALFLAWEMVNMRRSFFRMQPKSTKYFTQWFIDTWRNKLLFFSILIGFVTIFPLVYIPVLNTSVFKHAPITWEWGIVFVCAVLFFMGVEAWKWAKRVYFRRVTHKQHGGVKDLESRVFGHYYTIGGVALDSSPTLGSRTNTNEKEMREKGGNRYSSGGSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QW10</accession>
    <name>E3QW10_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminodeoxychorismate lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10192</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697387">
        <property type="protein sequence ID" value="EFQ35048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099068.1">
        <property type="nucleotide sequence ID" value="XM_008100877.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QW10"/>
    <dbReference type="STRING" id="645133.E3QW10"/>
    <dbReference type="GeneID" id="24415557"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10192"/>
    <dbReference type="eggNOG" id="ENOG502QQMK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020844_6_0_1"/>
    <dbReference type="OrthoDB" id="5288718at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="entry name" value="D-amino Acid Aminotransferase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="D-aminoacid aminotransferase-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="279" mass="31160" checksum="A4D8633F9063E04E" modified="2011-01-11" version="1">MPNEDFQLFTSLRYDPELLTVPKRHLDNAGWNARMTSSFYMLDLHRDRMLRAATYWNWTPAIETLRGAAGLQRLTEAIESFLAQHGKESALRVKVILTSEGSLSCEASSVPAVPLGNLFPQRLPSPGSSRQAGDPSQDSPMEVVIDKTETPQSEYTHYKTTKRAMYDTARDRESIALTDRKEVLLVNSKSGNIMEGSLTTPFFWRNGRWVTPPVSTEYIPENGSGGQDGTTRRWALERCLAVEEEVTAGSVVDGEPCWLSNGVRGFTFGKVQLNPTKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QW40</accession>
    <name>E3QW40_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PRELI-like family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10222</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697387">
        <property type="protein sequence ID" value="EFQ35078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099098.1">
        <property type="nucleotide sequence ID" value="XM_008100907.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QW40"/>
    <dbReference type="STRING" id="645133.E3QW40"/>
    <dbReference type="GeneID" id="24415587"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10222"/>
    <dbReference type="eggNOG" id="KOG3336">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067902_1_1_1"/>
    <dbReference type="OrthoDB" id="407630at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006797">
        <property type="entry name" value="PRELI/MSF1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037365">
        <property type="entry name" value="Slowmo/Ups"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11158">
        <property type="entry name" value="MSF1/PX19 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04707">
        <property type="entry name" value="PRELI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50904">
        <property type="entry name" value="PRELI_MSF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRELI/MSF1" evidence="1">
        <location>
            <begin position="1"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="196" mass="21884" checksum="D1072FEA5188737C" modified="2011-01-11" version="1">MKVFSNSVTFNYSWEEVSAANWRKYCPWNDKTTHVIAVDTIGRSVDPATGILRTERLITCKQSAPKWFASLVGGASAGADPDVSHVFETSYVNPTTKTVTMVSQNLTFSNIISVQESVVYKPISATQTQFVQDAQITALCGGWQRIKNGIEDQCVSRFRDNAIKGKEGFETVLAMSRRVFAEEREREMRVRQGMAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWC9</accession>
    <name>E3QWC9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10311</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697389">
        <property type="protein sequence ID" value="EFQ35167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099187.1">
        <property type="nucleotide sequence ID" value="XM_008100996.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWC9"/>
    <dbReference type="STRING" id="645133.E3QWC9"/>
    <dbReference type="GeneID" id="24415676"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10311"/>
    <dbReference type="eggNOG" id="ENOG502T65W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_727638_0_0_1"/>
    <dbReference type="OrthoDB" id="3692147at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="125"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="380" mass="43564" checksum="AE29D0652DE332BB" modified="2011-01-11" version="1">MDKASYITRKLGLRRRGLFTLFGRRTAAEGPTGNDAGDMALDPSALPLEQLTITCGTIEPANAEPMDLDPSPLDLEQLTITSGTIEPANAEPMDWDPSPLPSEPLTAVRCGPSPWESNFDRNRRQSRLIGLPDELLLQVMKVTEVADLYMLRQVSFSFWRIYRGRDFSEFNSDKLRPDTETNETIARRAKLQAFCGPCSQRRLLPENRSGRLGLRYRCRNMDCSHCKDCHSKPTFSVQQRQQPPEVRRCIGSYSFFRLCPHLMVPAYSIFKKAEEVSANHRERPSVIKYEEFVLGSCSQCKDLALQDMAGYERQYFYPPTLTLYKYLNSNKAQFYTRSNWCLPFCKIPEGDSLTAAFLLQKQEEFRNRYGNWAILAGWVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QX29</accession>
    <name>E3QX29_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Utp8 beta-propeller domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10561</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697392">
        <property type="protein sequence ID" value="EFQ35417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099437.1">
        <property type="nucleotide sequence ID" value="XM_008101246.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QX29"/>
    <dbReference type="STRING" id="645133.E3QX29"/>
    <dbReference type="GeneID" id="24415926"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10561"/>
    <dbReference type="eggNOG" id="ENOG502S1FV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013566_0_0_1"/>
    <dbReference type="OrthoDB" id="5330858at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018843">
        <property type="entry name" value="Utp8_b-prop"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10395">
        <property type="entry name" value="Utp8_b_propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Utp8 beta-propeller" evidence="1">
        <location>
            <begin position="41"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="889" mass="96884" checksum="5F8361CCA08097DC" modified="2011-01-11" version="1">MAPTFRIHRPDVLASLPRPLDHTKGQYHIGEVYAQKPGSKKRKRLEVVVGVDGEAANIYHVPSSGLRTSYPIPPQESFTCAPYSIRYQGAGASGRNNYTYLSTQDSTGAKITLCRDAIDVTGKTSSTSTSQRVRHKHPITYLFTSSAVDTTVVSDAPQSERGDVLGLCKDGQVLCLDGEALEQKWSAASYSLCKDLLPSTISEYEVEFSLHAAASEVLNGLFQGRQDAFGSFGRQIDPKTFNPDVLAIVVRADSEDTISRFLIILGVLPTVTSQPLVQLHVTPLPSQDDVAAELATYQLHIQSGKLLQLSGAVLRTYDLTSAVPKLQGRLPLPELTSFLQLSEHSALCLSQNSASMVNPTFHSVQASTAIQLPESTEQQKPTLITFLSKLDMAVAVVGSTLVSIQIERPKSHSKEGLLIDSIGRGLPRSDRVPASLPKTGDSTFENYLPGTLSDEYVKESLADVEKADGYLLAQDWKAFEGLLAQRFGVAIDQDAEVTGVQTPDWKWLERSDKYPAVDRRWVLYAISRVFSMDTQAEEGGLLRCMLPASNVMIYLIAAGHLTNANMSAAFRSELVEAASKESIIDKLVQRLVDMDPAMELLLNYVSATKLGEKELLLVIRIIMRSLDQQSRLLLPAPTETKEEEYVAMEIDHLEKELEMAEYHLGDDTNLRARALTTAFEKLSNYSSVATVRALRETFNPTEVLSLIHLLRIQLIGSAWTSRYVDSTNFDKDEAARAPPDGAISLIAELLSRCIDSVGPSGWLTNGTSVGDRADAADFITALKLEVSAALEGLNEAVYLDGIVGEAVQYGRAVKAGVKTAPSGRAQALAKPVSLDVESSPHLPLGLVSKQSVSNLKIVSGGEVLERSSREKGHLLSQKVKAYSLERISI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYD7</accession>
    <name>E3QYD7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC-type Fe3+ transport system</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_11066</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697402">
        <property type="protein sequence ID" value="EFQ35875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099895.1">
        <property type="nucleotide sequence ID" value="XM_008101704.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYD7"/>
    <dbReference type="STRING" id="645133.E3QYD7"/>
    <dbReference type="GeneID" id="24416431"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11066"/>
    <dbReference type="eggNOG" id="ENOG502SDBY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026974_5_0_1"/>
    <dbReference type="OrthoDB" id="124329at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30006:SF2">
        <property type="entry name" value="ABC TRANSPORTER SUBSTRATE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30006">
        <property type="entry name" value="THIAMINE-BINDING PERIPLASMIC PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180979" evidence="2">
        <location>
            <begin position="20"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ35875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="355" mass="39599" checksum="1880A00F3EA44650" modified="2011-01-11" version="1">MFRTLLALGLLGTRALVGAATEIETRTIDEIYQAALAEGGVVTLFQGGDETTQANGLKTNFEKRFPGMTLNVTVDVSKYHDGKIDDQIAANNVYVDSTILQTLHDFPRWASEDALLDYAPLGYDKILPEFKNNETAAYYGLFIISWGGQWHSGELPNITAPVEWEDWVNPDLKDKLVLTYPNDDDAVLFAFNLILKQYGPAWFDKLLALNPRWVRGTQTPSTIFRKNDTQWAATFTSSGNLNPVSPIKSSFPVKGQFVSWPQTGGILKNAPHPEGAKLLHSYILSAEYQNIRGGWSVRGDVPPPPNYPSILEMPGTDPTAFGKWMSDRVVVERLRFWFEDRIGTTQGLSPLIDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYL6</accession>
    <name>E3QYL6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_11098</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697405">
        <property type="protein sequence ID" value="EFQ35954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099974.1">
        <property type="nucleotide sequence ID" value="XM_008101783.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYL6"/>
    <dbReference type="GeneID" id="24416463"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11098"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_6_1"/>
    <dbReference type="OrthoDB" id="2250022at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000057">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF62">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="242"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="320"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="352"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="383"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="459"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ35954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="507" mass="55598" checksum="FD679E69C396A3C2" modified="2011-01-11" version="1">MNTINRRSVEPTDAGICTRDSSKTEPLRDKNAEAILEHTEQASDEEKTAQHLPRVTAPIEALGLENWQDLEKKLVKRLDMTLMPMLWVLYLFNYLDRASISQARLSSFEADLGLTDTQFATAVAVLVPGYIAAQIPSNMILPYVRPSLYLPCCAIVWSGVSASMAGVRNYNGLVACRVILGLCEAPLLPGAIYLMSCWYTRKEIALRTAILYTGLVLAMASSGLIATGVYEGLEGSQGMAGWQWLFIVLAIAGSCCALVATVLLPDYPHSKTGSARWSLTEDMRLLAVARIQADRVSLPQANSTSIWYGLKLTCMDYKTWIFVAINISISAAYGFLNFFPSIVRGFGFESRTTTLLLTAPPYVFAAVASLCNARSSDHFKERGYHMIGPVIAAILGYIVCTATGNVPARYAASFLYIGVGTLGRTPEKRATAIPVINVLGQIGNVIAPYFFPDRDEPRYLMAFLLMMGFAAIGVAFCLLLKFCLIRSNKKLWAKAQEDGTAYNPYTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYP6</accession>
    <name>E3QYP6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_11128</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697405">
        <property type="protein sequence ID" value="EFQ35984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100004.1">
        <property type="nucleotide sequence ID" value="XM_008101813.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYP6"/>
    <dbReference type="GeneID" id="24416493"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11128"/>
    <dbReference type="eggNOG" id="ENOG502SJPU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013756_1_0_1"/>
    <dbReference type="OrthoDB" id="10029326at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507:SF8">
        <property type="entry name" value="MFS GENERAL SUBSTRATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507">
        <property type="entry name" value="ZGC:174356"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="102"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="218"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="301"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="337"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="380"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="410"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="450"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="486"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ35984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="510" mass="55325" checksum="A96009C4C714A0C8" modified="2011-01-11" version="1">MPSATQLIDESISCAATGASAAAYRQRKAGIRALLALVLLVNLAASLYQLPLSRVIERRLCREHYLIADPSVIDRDGNVEERLCKVDGVQQGLAWIQGTMETSWIVGDFVMTIPLGFLAERYGRRTILCLNLAPRIVMLAWAVIVGYFEQIMPTKAIVASPFLSVLGGDCVFNSITYAIASGITDDHVQRATYFGWMSSVSYVVNLLGPALASASMSLLLWLPFWIGISLLLLAIPAISFIGDSPENHSRASVSRNTDDQARPLLSSPVLKAQDAEASLLRSIVQRFGALRSIIASHPRNMSLLLISFILTSLASSDTKLLVQYISKRYGWTFASTGYLLSAKAVVNFTLLTVIVPAILRSGQKRSLHIPPEVVSHRMNMCYAKICLVISILGALAIALATQIWMLVPSLFLYALGSALPVFTLSLLKSPYVAPKRNERSLDMVDPESHVFSIVMMVKTSGSLLGAPLMMVLWVRGISLGGAALGIPYFVSASCYIVALAVLSSISGRQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYR7</accession>
    <name>E3QYR7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CRAL/TRIO domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_11149</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697406">
        <property type="protein sequence ID" value="EFQ36005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100025.1">
        <property type="nucleotide sequence ID" value="XM_008101834.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYR7"/>
    <dbReference type="STRING" id="645133.E3QYR7"/>
    <dbReference type="GeneID" id="24416514"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11149"/>
    <dbReference type="eggNOG" id="KOG1471">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014001_4_2_1"/>
    <dbReference type="OrthoDB" id="30289at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.20">
        <property type="entry name" value="N-terminal domain of phosphatidylinositol transfer protein sec14p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051026">
        <property type="entry name" value="PI/PC_transfer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45657">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN YKL091C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45657:SF3">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G09260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03765">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="2">
        <location>
            <begin position="110"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="365"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="373"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="415"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ36005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="437" mass="48700" checksum="3C62B100CE5E8C02" modified="2011-01-11" version="1">MTTDTAAASDPAARVESHASTASNVGYPHGHLGHLTEHEEAQLAAFRKLIEDKGLYKPGPPASHDDPTLLRYLRARRWVPEDALTQFKDTEEWRAANDIDVLYRTIDLDAFEQSRRLYPQWLGRRDRRGIPVFLFEVKTLDAKTIANYEKAGRDSSFSKAKFDGKTPAGMLRLFALYESLTRFNQPFSTQLQDREHSDTPITLSTNIVDISGVSLKQFWNLKSHMQAASQLATAHYPETLDRIFIIGAPVFFSTVWGWVKRWFDPITVSKIFILSPHEVHPTLEQFIEPRNIPKQYGGELEFAFGDQPTVDPAWEGVVRWEPGHDRFRARPAVWRETPDGERMECVGLGSVGGVEQHELICSVPKTWPPSQPPAAAEPTPAATPVTKEGSVADGTQTEPVEVSPAPELQKLSLSDTKEIAEKHTEGSTASPPTGVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZ72</accession>
    <name>E3QZ72_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_11304</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697411">
        <property type="protein sequence ID" value="EFQ36160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100180.1">
        <property type="nucleotide sequence ID" value="XM_008101989.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZ72"/>
    <dbReference type="STRING" id="645133.E3QZ72"/>
    <dbReference type="GeneID" id="24416669"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11304"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_1_1"/>
    <dbReference type="OrthoDB" id="5325318at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF115">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ36160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="254" mass="26669" checksum="06FAAF9AB9795CB2" modified="2011-01-11" version="1">MSKFSLTGRVAVVTGSGRGCGLAFAQGLAEAGADVAIFDLIDPDPVALEQLSAATGIRAKAYVVDVTSVSSLEKGFASVATDFGSKLDIFVACAGVNKNVEFLDTEEADFDRLYGVNCKGLYFSAKLAAKAMISNGTKCGSIIFVASIASHIAIRSQRSTAYCGTKGAVRAMVAPIAAELDKHGIRVNSISPGYVRTEMTAPFPDLLESWKDEIMNGRVAEPDDIKGACVFLASDASRYCQASDIVVDGGVTKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZI9</accession>
    <name>E3QZI9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_11422</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697416">
        <property type="protein sequence ID" value="EFQ36277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100297.1">
        <property type="nucleotide sequence ID" value="XM_008102106.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZI9"/>
    <dbReference type="STRING" id="645133.E3QZI9"/>
    <dbReference type="GeneID" id="24416786"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11422"/>
    <dbReference type="eggNOG" id="KOG2614">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_12_2_1"/>
    <dbReference type="OrthoDB" id="2431938at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="7"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ36277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="449" mass="50370" checksum="6B7D0754B04154BB" modified="2011-01-11" version="1">MTNESFRVIIIGGGPSGITAAYALYHAGIDFVLLERRNEVAEDQGASLVLSPSSLRVFHQFGILDQLLEIGGKIKINKAFTVDGQRFMHADAYGLLKDHHGIEPLAFHRAHLVQALYDNLPEAAKLRYITGKKLASITSTETGVTVTCVDGSSYTGSIVIGADGVHSMVRQEMRRLAIKSNPSYETTWDSVKPYKTNYVCAWASFPRPSEPGLNHETHSTDRSIMYITGKERGWIFLYKKLTSSTTDRITLSSDEVDDFAKEFMDWPIAENLKVKDVWEERYSAGGAGLEEGVCGNWSWNGRVVLVGDAAHKFTPNAGLGFNNGIQDVVALSNKLHRFVSAPSRSPLDFATLESRLKEYQSERRETLMSDLDHSALVTRMHAWSSTWTWIMARYVMSWSFMQRMFITYVLSPKIQRIGVIDFLPTSEPFEGTFKWQHPLSKNAPNDPTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3R041</accession>
    <name>E3R041_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ulp1 protease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_11624</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C48 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697426">
        <property type="protein sequence ID" value="EFQ36479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100499.1">
        <property type="nucleotide sequence ID" value="XM_008102308.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R041"/>
    <dbReference type="STRING" id="645133.E3R041"/>
    <dbReference type="GeneID" id="24416988"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11624"/>
    <dbReference type="eggNOG" id="KOG0778">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_333165_0_0_1"/>
    <dbReference type="OrthoDB" id="4851359at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019783">
        <property type="term" value="F:ubiquitin-like protein peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.395.10">
        <property type="entry name" value="Adenoviral Proteinase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003653">
        <property type="entry name" value="Peptidase_C48_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02902">
        <property type="entry name" value="Peptidase_C48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50600">
        <property type="entry name" value="ULP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like protease family profile" evidence="5">
        <location>
            <begin position="517"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="191"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="443"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="256"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="274"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="443"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ36479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="900" mass="99118" checksum="31F7AA79D9CC48FE" modified="2011-01-11" version="1">MAHSGIDIPLDDDSGMLQSAPLLETLDELNKIDIIQIEEHIDQLWDKLHANFAETRDSSITGGASFIVWALKKVERPLLCRILDREHKAVLQSITPDLLGRLTSLADRWDASPGLLLDLFSHKIVSSRACIDLLNSLHKASPELLLTDLVDQFNSVPRHNTRRWGPRATKNAISMLKEAVGHFKPALVERKHRPAEDPTPSPEGDSSSNAGGEANDSPDSSNEHESDSGTGGKPTRDKRRRPLPAEAPSTRTRRPAAGDDTTRGEGVQRRPTVQPVTGNSTQVEQTQAPTTPRADLPAASPERPRKERQTLAASPVSSEFPFQFDGNHDLGESDLDAPPSMHYSDDDEHDGFQMPESDPWTGPSRLQAPQRLRKACPGAQEPPAPKRRRLTDIGPMDCHVTSDSDSLGGGSIITNISIDLTPPLPSSPVVGDGAAFVPVKARPASLSPPRLSPVVRDGPPSPSPTRPAGPSSSCVIVSDQCGREVNPISDTSEEMNPTSIIPYVPRPPSVLKHRPALADISENLYRLSPGQMLNDTIIDTLLHRLSLMNGQVLAISSLVLRSQNIPDRVFDAIARANYDRILMPICRNIHWVLFVFSRQDNKVRLFDSFPGLLPVDQVADAVVLPFLRRLGVSDGIQVDLDASQCARQQNAVDCGLFLILSAYYVLGASEYVPADVTSETLDAYRQHFLQCLLTSTAAALPPDEIKGIAVLGKVEKDRLASLARYTLELRARRPSLQRLLNSADIFCNSTAVIRQLHQDELRKWETCFIASALANAHATHARLFRKAFEMQSERRKKMEAMRRRYELRMAIDTILDNVDPDDPRGPSIGRSEAAHQSEAKGMMNLWCAANMAADFFLEDASSNPAEQAGHNDYNPFTMCVVHIIITRYARQKLGRIENRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3R062</accession>
    <name>E3R062_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_11645</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697430">
        <property type="protein sequence ID" value="EFQ36500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100520.1">
        <property type="nucleotide sequence ID" value="XM_008102329.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R062"/>
    <dbReference type="STRING" id="645133.E3R062"/>
    <dbReference type="GeneID" id="24417009"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11645"/>
    <dbReference type="eggNOG" id="ENOG502T4Y5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1372106_0_0_1"/>
    <dbReference type="OrthoDB" id="4851795at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003181049" evidence="2">
        <location>
            <begin position="21"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ36500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="199" mass="19539" checksum="5742238BEC965564" modified="2011-01-11" version="1">MRYTTITLLAIGLLTGNALTAPAPQAGGAVGAFGGGGQDGGNNQGNQNAQGNQGNQGNQGNQNNQGNQGNQNQGNQGNQGNQGNQGNQNNQGNQGNQNQGDQNNNNGNNGNNGNNNGNNGNNNNGNNENNGNNNGNNGNNGNNNNGNNGNNGGQGGDANAAAEFEGLACTDGTGAGSCQADGQCDVNGNVAVVEGQCGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0F1</accession>
    <name>E3R0F1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alcohol dehydrogenase GroES-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_11734</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697441">
        <property type="protein sequence ID" value="EFQ36589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100609.1">
        <property type="nucleotide sequence ID" value="XM_008102418.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0F1"/>
    <dbReference type="STRING" id="645133.E3R0F1"/>
    <dbReference type="GeneID" id="24417098"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11734"/>
    <dbReference type="eggNOG" id="KOG1198">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_16_0_1"/>
    <dbReference type="OrthoDB" id="3233595at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08249">
        <property type="entry name" value="enoyl_reductase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047122">
        <property type="entry name" value="Trans-enoyl_RdTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348:SF5">
        <property type="entry name" value="OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G01420)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="3">
        <location>
            <begin position="9"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ36589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="348" mass="37582" checksum="1E2FD2472B3B637F" modified="2011-01-11" version="1">MKEAIVNADISVTVKDSPIPTPGPGELLIKVVVSGTNPKDWKVPRWLNVAANSGDDVAGVVETVGSEVYEFAKGDRVAGFHVMRSEHGSFAEYAIVPAFSAFHIPKNVSFEEAATVPLAAYTAATALFHSLEVPSPWDRTRAKKTPLIIYGVSTAIGAFGVKLAKKAGVYPLIAVGSKNSAFVTPLLEKEKGDVFLDYTQFESQDKLAEKLREVIKETGQPCFRVFDTVSENGSFEMLSKAIAGPPEEGTGFKPKITTVLPSKDYTTVDKSVEIVLTSVGRVHEEEGEGQLFGLIWARAFADGLRTGWMKAHPFEVVEGLQGVERALKGLENGSVRAKKMVIRVAEGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0L1</accession>
    <name>E3R0L1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_11795</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697455">
        <property type="protein sequence ID" value="EFQ36649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100669.1">
        <property type="nucleotide sequence ID" value="XM_008102478.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0L1"/>
    <dbReference type="GeneID" id="24417158"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11795"/>
    <dbReference type="HOGENOM" id="CLU_2722080_0_0_1"/>
    <dbReference type="OrthoDB" id="1046782at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ36649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="72" mass="8179" checksum="62AE797D3F1C8E95" modified="2011-01-11" version="1">MNRLCRFACSHGYCPPDVCTTAVVDKDEDDGIIEVGWSSENPNYFNYTGARLANADKCLIYQNPKLRDEVQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0M8</accession>
    <name>E3R0M8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_11812</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697460">
        <property type="protein sequence ID" value="EFQ36666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100686.1">
        <property type="nucleotide sequence ID" value="XM_008102495.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0M8"/>
    <dbReference type="GeneID" id="24417175"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11812"/>
    <dbReference type="HOGENOM" id="CLU_2440712_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ36666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="90" mass="10443" checksum="7D534088587F621A" modified="2011-01-11" version="1">MWTSDAPILVVVLNKIPSYKKKAVNNSTRRRLVIYNMKKLGKEKLLPEGAIDNKTMPRFISLCAACVYWNVHVLSHIHGYRHVHHFDNCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3R102</accession>
    <name>E3R102_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Trypsin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_11936</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697539">
        <property type="protein sequence ID" value="EFQ36790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100810.1">
        <property type="nucleotide sequence ID" value="XM_008102619.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R102"/>
    <dbReference type="STRING" id="645133.E3R102"/>
    <dbReference type="MEROPS" id="S01.412"/>
    <dbReference type="GeneID" id="24417299"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11936"/>
    <dbReference type="eggNOG" id="ENOG502S8GA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030648_2_0_1"/>
    <dbReference type="OrthoDB" id="3762657at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21112">
        <property type="entry name" value="alphaLP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.50">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004236">
        <property type="entry name" value="Pept_S1_alpha_lytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001316">
        <property type="entry name" value="Pept_S1A_streptogrisin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035070">
        <property type="entry name" value="Streptogrisin_prodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02983">
        <property type="entry name" value="Pro_Al_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001134">
        <property type="entry name" value="Streptogrisin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00861">
        <property type="entry name" value="ALYTICPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <keyword evidence="2 9" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003181072" evidence="9">
        <location>
            <begin position="20"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1A alpha-lytic prodomain" evidence="11">
        <location>
            <begin position="109"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="10">
        <location>
            <begin position="211"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="223"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="252"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="333"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="208"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="291"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="327"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001134-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001134-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ36790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="379" mass="38101" checksum="81ED4863E404028B" modified="2011-01-11" version="1">MELSRYLALLAVILPVAYGAPTQAATSLHPKILAAMKRDLGLDAEAATARVAFEHGATNIIEQLRTSTGDSFAGAWISADGTTLNVGVTDEALAAEVTAAGATPAIMSNSLSKLEQAKLAIDNLDINQSEARDTSSADSGIASYYVDVASNKLILEALAGSVAHAESLATQVGLAASDFEVRTVEEMPTTFATIRGGDAYYINRSARCSIGFSVTTGFVSAGHCGTVGSSATTSSGAALGSFAGSVFPGSADMSFIRSSSGNTLSGTINGYSRGTLPVSGSTVAGVGSSICRSGSTTGVYCGTVGALGATVNYAEGRVTGLTRTSACAEPGDSGGSFYSGAQAQGVTSGGSGNCRSGGTTYFQPVNEILSTYGLTLVRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3R140</accession>
    <name>E3R140_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Expansin-like EG45 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_11975</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697590">
        <property type="protein sequence ID" value="EFQ36828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100848.1">
        <property type="nucleotide sequence ID" value="XM_008102657.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R140"/>
    <dbReference type="SMR" id="E3R140"/>
    <dbReference type="STRING" id="645133.E3R140"/>
    <dbReference type="GeneID" id="24417338"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11975"/>
    <dbReference type="eggNOG" id="ENOG502QVAP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026963_3_1_1"/>
    <dbReference type="OrthoDB" id="406505at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22271">
        <property type="entry name" value="DPBB_EXP_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.760">
        <property type="entry name" value="Expansin, cellulose-binding-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036749">
        <property type="entry name" value="Expansin_CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051477">
        <property type="entry name" value="Expansin_CellWall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836:SF21">
        <property type="entry name" value="EXPANSIN-LIKE PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49590">
        <property type="entry name" value="PHL pollen allergen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003181143" description="Expansin-like EG45 domain-containing protein" evidence="3">
        <location>
            <begin position="24"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="28"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="65"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ36828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="319" mass="33342" checksum="A6B390344B62A781" modified="2011-01-11" version="1">MIPGHISHYAVAILAALSAAVDAKACKARHHHHHQGKPADNSTASVALPPQTTPPPSATTLATFVQASMQPSQANAAESPALTSSSNPLNAGAASTTMSSSAVAALQTSSSETFIGLGTRYGGSCTEKDCWENGACSFVGYDLPAGIDGSTCVSDDIWNNGANCGGCISVTYQGKTLTIMVTNRTGGNATHLDMTPDTWAKLTNGNPGGGVNGIEWEWITCPFADSTPLQVHMHGGASQYWFAAMIENATLRTKKLEVSSDQGATWKTATLHDPNMWEITGTLPSATCWVRVTSVNGVEVVVKDVVLQSGKITKATENY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>E3R165</accession>
    <name>E3R165_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_11999</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697672">
        <property type="protein sequence ID" value="EFQ36853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100873.1">
        <property type="nucleotide sequence ID" value="XM_008102682.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R165"/>
    <dbReference type="STRING" id="645133.E3R165"/>
    <dbReference type="GeneID" id="24417362"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11999"/>
    <dbReference type="eggNOG" id="KOG0156">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022195_0_3_1"/>
    <dbReference type="OrthoDB" id="1844152at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE AUSG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="443"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ36853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="513" mass="57860" checksum="1BFF829A7C2B24E3" modified="2011-01-11" version="1">MLQISHNPLHPLAQYLPQWVSRSLSSILLVAAFSLIILTLLSLISTQRHLKDIPLINPPNSLFQTTAEIAKQYSTNPVTIIERGRNIYPDQPYRMITNQGTVVVMPPQHAEEIANKSELNLMARARTECHAGTPGFSGLTTGPDGDRLAIDVVKKPLTKSLEWHEVQLLPRMLDIIAQTSSRVFLGEELCRNEDWLRITKTYTSKAFVLAGKLGNIPRPFRPLLHWFIPGMKELRDLCAKAEAIIQPIYNARQKAKARALADGKAIPTYDDCIEWAEAEAHASYQPAMLQMNIAVAAFHNTAELLSRVVLNIAHHPHIIRELREEAIDVLKADGWRKTALSKMKKLDSVIKETLRLKPSGTLTMRREATSPTTLSTGLTLKTGDALIVDPFNSFRDPTLYENPEQFIPWRFLHWQNEPGKQHLAHLVSTSPAHLGFGHGIHACPGRFFAADEIKIVVCHMLIQYDWKPPPMSSWKPVHAGIFMVTPPDTVLLFRRRPHPEIDVKRLPPTLVRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q1Z3</accession>
    <name>E3Q1Z3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00238</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089114.1">
        <property type="nucleotide sequence ID" value="XM_008090923.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q1Z3"/>
    <dbReference type="STRING" id="645133.E3Q1Z3"/>
    <dbReference type="GeneID" id="24405603"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00238"/>
    <dbReference type="HOGENOM" id="CLU_1378021_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="59"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="198" mass="22029" checksum="BFEE2C6E56F5F8E7" modified="2011-01-11" version="1">MTLAPPPPYPPPTSNSVHIHPLQQQSIPEPQYAPVPIPAAYNQAPNHTGSQQHPPTPVQQGYPPTPQLYQPQPYQPRPLAQQQTQQQQQQQPNLLPTPISPPCSVNVVEQACSSYFPATMAPQKHAVYNPQDWAGRPYGQEPYTPAATPSASYSPQTAQAYSSHPQWRFHDHDTVVTPMILSRQVIEQARNGGRDDIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q241</accession>
    <name>E3Q241_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NCS1 nucleoside transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_00286</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089162.1">
        <property type="nucleotide sequence ID" value="XM_008090971.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q241"/>
    <dbReference type="GeneID" id="24405651"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00286"/>
    <dbReference type="eggNOG" id="KOG2466">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021555_3_0_1"/>
    <dbReference type="OrthoDB" id="2018619at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015205">
        <property type="term" value="F:nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4160.10">
        <property type="entry name" value="Hydantoin permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045225">
        <property type="entry name" value="Uracil/uridine/allantoin_perm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30618:SF4">
        <property type="entry name" value="ALLANTOIN PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30618">
        <property type="entry name" value="NCS1 FAMILY PURINE/PYRIMIDINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="249"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="341"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="364"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ25142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="431" mass="47959" checksum="B528028144ADE754" modified="2011-01-11" version="1">MAQKTVRRIREAATLDFDESRHEEASAWSKSTSSRCRRPDAPGAGSTFSVPGRFGLLYHTRSSLNVATWQTPDTFLTQGLSVGQAMAVIVVSRALCCLFAIFVAWCGLTWHIGFTVQNRYTWGFRASYIPSLQRILLNFIWTALQCWNGGKLVTVCITAIWPSFAKIPNTLGAGTTTTTYEMVGFIVFWVVSVPFLFIRPEKFKKPFFVSSVACGVGMVALLIWSLAVAGGVERVVQLAVERLIIGTVSVYWITEVLVCLGGLVTTAACQKIYGHIYWNPPDLLMVMMDHGQGSPASRAAVFFLALAFAFTSMFENVCSNAVAGGIDLAGLFPRYIDIRRGALITFFAAWIIQPWQLINQAATFVAVLNSFAVFLAPIMGVMVCDYFVLRRQRIKLSHLFHPEGSDYWYWHGVNWRVIPCWIAGWRPPSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q346</accession>
    <name>E3Q346_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Homeobox domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_00169</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TALE/TGIF homeobox family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089045.1">
        <property type="nucleotide sequence ID" value="XM_008090854.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q346"/>
    <dbReference type="STRING" id="645133.E3Q346"/>
    <dbReference type="GeneID" id="24405534"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00169"/>
    <dbReference type="eggNOG" id="KOG0773">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055480_0_0_1"/>
    <dbReference type="OrthoDB" id="10056939at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000059">
        <property type="entry name" value="TGFB-induced factor homeobox 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008422">
        <property type="entry name" value="KN_HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050224">
        <property type="entry name" value="TALE_homeobox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11850">
        <property type="entry name" value="HOMEOBOX PROTEIN TRANSCRIPTION FACTORS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05920">
        <property type="entry name" value="Homeobox_KN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 8 11" id="KW-0371">Homeobox</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Homeobox" evidence="10">
        <location>
            <begin position="274"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="8">
        <location>
            <begin position="276"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="45"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="342"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="55"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="128"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="363"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="391"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ25025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="403" mass="45376" checksum="8DB4BB256602C731" modified="2011-01-11" version="1">MAAPSPHSAFKQYPWDGGRSTSDYSRPRTETERIALPSIRQAIPELHLRLQPQESSTTRTTSSNTSPTVGYAGVMTPPEYVHSPSSNKRRRLSVDEEQDGERVSRVPRLYESPARLPQRQISPPLASRSVTESWTGSARTSPYMSASGMPSIRSPAMELNERPEMRTTLPSLPPMNFDREPVPMQRVRGHSQDDFQPIRPSMGMSGAPPMMEAAPAYRPSGYAYGYHHPSRVQSLSLGSIHPFDRTPFSSAGYGHYPEFMRIGELSAMGMHGDSKQRKRRGNLPKETTDKLRAWFVAHLHHPYPTEDEKQELMRQTGLQMNQISNWFINARRRQLPTMISNARAESDAMSSRSGESKILPSTERSEYDDGKRSSVPLSEGEAFDEDLDSLKHRRSAHIKRGSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q396</accession>
    <name>E3Q396_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Alanine--tRNA ligase</fullName>
            <ecNumber evidence="15">6.1.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Alanyl-tRNA synthetase</fullName>
            <shortName evidence="15">AlaRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ALA1</name>
        <name evidence="18" type="ORF">GLRG_00642</name>
    </gene>
    <organism evidence="19">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14 15">Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 15">
            <text>tRNA(Ala) + L-alanine + ATP = L-alanyl-tRNA(Ala) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:12540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:9923"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78497"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="15">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="15">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="15">Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.7" evidence="15"/>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089518.1">
        <property type="nucleotide sequence ID" value="XM_008091327.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q396"/>
    <dbReference type="STRING" id="645133.E3Q396"/>
    <dbReference type="GeneID" id="24406007"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00642"/>
    <dbReference type="eggNOG" id="KOG0188">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004485_5_0_1"/>
    <dbReference type="OrthoDB" id="2423964at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004813">
        <property type="term" value="F:alanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070143">
        <property type="term" value="P:mitochondrial alanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00673">
        <property type="entry name" value="AlaRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.130:FF:000004">
        <property type="entry name" value="Alanine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.310.40:FF:000003">
        <property type="entry name" value="Alanine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000011">
        <property type="entry name" value="Alanine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.980.10:FF:000004">
        <property type="entry name" value="Alanine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.980.10">
        <property type="entry name" value="Threonyl-trna Synthetase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00036_B">
        <property type="entry name" value="Ala_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002318">
        <property type="entry name" value="Ala-tRNA-lgiase_IIc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018162">
        <property type="entry name" value="Ala-tRNA-ligase_IIc_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018165">
        <property type="entry name" value="Ala-tRNA-synth_IIc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018164">
        <property type="entry name" value="Ala-tRNA-synth_IIc_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050058">
        <property type="entry name" value="Ala-tRNA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059090">
        <property type="entry name" value="ALA1_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023033">
        <property type="entry name" value="Ala_tRNA_ligase_euk/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00344">
        <property type="entry name" value="alaS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11777:SF9">
        <property type="entry name" value="ALANINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11777">
        <property type="entry name" value="ALANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26023">
        <property type="entry name" value="ALA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01411">
        <property type="entry name" value="tRNA-synt_2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00980">
        <property type="entry name" value="TRNASYNTHALA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101353">
        <property type="entry name" value="Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="ThrRS/AlaRS common domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50860">
        <property type="entry name" value="AA_TRNA_LIGASE_II_ALA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 15 18" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 15" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 15" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 15" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 15" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="7 15" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alanyl-transfer RNA synthetases family profile" evidence="17">
        <location>
            <begin position="6"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="917"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="599"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="603"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="718"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="722"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00055137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EFQ25498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="955" mass="106992" checksum="0E3CE4754C0465A4" modified="2011-01-11" version="1">MAEPKWPGVVVRKTFLEFFEKRGHTIVPSSSVVPHNDPTLLFTNAGMNQFKPIFLGTISKADPMYPLKRATDTQKCIRAGGKHNDLDDVGKDSYHHTFFEMLGNWSFGDYFKKEAIEWSWELLTKVYGLDPDRLYVTYFEGNPDMGLEPDLEAKGLWQSVGVPEDHILPGNMKDNFWEMGDQGPCGPCSEVHYDKIGGRNASDLVNQDDPMVVEIWNNVFIQYDRQPDRSLKSLPAKHVDTGMGFERLVSALQNTVSNYATDIFTPLFKRIEEVTGARPYTDKYGADDVDGIDTAYRVIADHIRLLTFSMSDGAVPNNDGRGYVVRRVLRRGVRYARKYFNAEIGSFFSKILPALVDQMGEQFPEIVKKQDDIREILDEEEEAFARTLDRGEAQFEKYANAAIKKGEKKLSGAEVWRLYDTFGFPVDLTKLMAEERKLEIDDDEVKAAQDKAREASKVVKNSVQTFAKLNVHQIAELEQQLNVARTDDDAKFVKGDSKAKVQLIYDGKGFVKSTKDIAENTPLGLLLDKTNFYAESGGQVADTGRIVIDDVAEFKVLDVQNHGGYIVHNGYLEYGVLSSGNEVICEYDELRRSPIRNNHTATHILNHSLREVLGDDVNQKGSLVDNEKLRFDFSHKTGVTIPELKKIEDFSNSYIRQNGKIYAKEVDLDLAKGIEGVRAVFGETYPNPVRVVSVGVDVDTLLANPKNPEWRKISVEFCGGTHVDQTGLIKDLVIVEESGIAKGIRRIIAYTGDAAHQVQREADEFSKRLDALEVLPFGPEKEQEIKTTQHALNQLTISTLTKEDIKKRFDKIIKAVTDEQKKRQKAEAKTALDTVVAHFDKNKDSKWFVGQLPISANAKAIGEVVKHFQSKDKERSVYLFGGSKNEGSVAHGVYVGTHLSSQGVTAEQWAAQVSEIVGGKSGGKEPTRQGQGTKAENLDEAVATAEKWLKEKLNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3L5</accession>
    <name>E3Q3L5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Succinate-semialdehyde dehydrogenase</fullName>
            <ecNumber evidence="8">1.2.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_00761</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5 8">
            <text>succinate semialdehyde + NAD(+) + H2O = succinate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13217"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57706"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 8">
            <text>succinate semialdehyde + NADP(+) + H2O = succinate + NADPH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13213"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57706"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Amino-acid degradation; 4-aminobutanoate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.16" evidence="8"/>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089637.1">
        <property type="nucleotide sequence ID" value="XM_008091446.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3L5"/>
    <dbReference type="STRING" id="645133.E3Q3L5"/>
    <dbReference type="GeneID" id="24406126"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00761"/>
    <dbReference type="eggNOG" id="KOG2451">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_0_1_1"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="UniPathway" id="UPA00733"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004777">
        <property type="term" value="F:succinate-semialdehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036243">
        <property type="term" value="F:succinate-semialdehyde dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009450">
        <property type="term" value="P:gamma-aminobutyric acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07103">
        <property type="entry name" value="ALDH_F5_SSADH_GabD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000004">
        <property type="entry name" value="Succinate-semialdehyde dehydrogenase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000005">
        <property type="entry name" value="Succinate-semialdehyde dehydrogenase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050740">
        <property type="entry name" value="Aldehyde_DH_Superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010102">
        <property type="entry name" value="Succ_semiAld_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01780">
        <property type="entry name" value="SSADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353">
        <property type="entry name" value="SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353:SF5">
        <property type="entry name" value="SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="9">
        <location>
            <begin position="60"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00050387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00052698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ25617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="533" mass="56560" checksum="B7475D1471B0B79A" modified="2011-01-11" version="1">MPILLQKAVAPASRFVPRTLFRSVRTPVIPFALRAASTMVPKLKDPSLLKQDVCYVNGEWVKAKSGKTFDVNDPATGEKIASCPEFAKADTDAAIAAAATAFETFRTKTGRERSKLLRRWHDLMMENADDLTTLITWENGKPVADAKGEVTYAANFFEWFSEEAPRIYGDTIPSSVPGNRVWTVKEPVGVCGLITPWNFPAAMIARKIGPALAAGCTVVCKAPGETPFTSLAIAELGHRAGVPKGVVNVVTALGNTPEVGAALTASPTVKKISFTGSTGVGKLLMGQCAGTLKKLSMELGGNAPFIVFDDADVDAAVAGAVASKFRSSGQTCVCANRIYVQSGVYDEFADKFAAKVREFAVGNGFADGTTHGPLIHDRAVDKAEAHVRDAERKGASVVVGGARMDALGRNFYEPTVITGMTADMAMATEETFGPVAGLFRFDTEAEVVALANATNVGLAGYFFSRDIHRVHRVAEHLEVGMVGVNTGLISDPAAPFGGVKESGFGREGSLYGISEYQVTKMITYGGMGQPLQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3N8</accession>
    <name>E3Q3N8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00784</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089660.1">
        <property type="nucleotide sequence ID" value="XM_008091469.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3N8"/>
    <dbReference type="GeneID" id="24406149"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00784"/>
    <dbReference type="HOGENOM" id="CLU_2867536_0_0_1"/>
    <dbReference type="OrthoDB" id="10500315at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178180" evidence="1">
        <location>
            <begin position="21"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="64" mass="6361" checksum="2CDC63CD74513214" modified="2011-01-11" version="1">MPSIARLILLTATLAAMVQAAPVASSSEPGVTILSAEEVEPHTGPVVPVSAPDGILSVVSEIAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3Q6</accession>
    <name>E3Q3Q6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00802</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089678.1">
        <property type="nucleotide sequence ID" value="XM_008091487.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3Q6"/>
    <dbReference type="GeneID" id="24406167"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00802"/>
    <dbReference type="eggNOG" id="ENOG502RAW2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1511637_0_0_1"/>
    <dbReference type="OrthoDB" id="61113at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="2">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ25658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="184" mass="20207" checksum="B8E0BDCDB16DA30D" modified="2011-01-11" version="1">MALDVLILIVPIPLLFSKETISQTRKGLLGLFFIGILINAIAAWRIVANKATEDEGADPMWIFPPIILLGETENRLSLALASIPVFWPVVAKTWQALGIVVTHEIQIERTQRPPDAGEMDRTALEHASVVANRAATEDEPNKAALGHPARLSDVCGYERKLISPFAESERKGQYQSSTQVVSLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3T1</accession>
    <name>E3Q3T1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00827</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089703.1">
        <property type="nucleotide sequence ID" value="XM_008091512.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3T1"/>
    <dbReference type="STRING" id="645133.E3Q3T1"/>
    <dbReference type="GeneID" id="24406192"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00827"/>
    <dbReference type="eggNOG" id="KOG0667">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016810_0_0_1"/>
    <dbReference type="OrthoDB" id="1046782at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359:SF37">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SBK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="298"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="409"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="635"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="699"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="647"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="699"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="747"/>
            <end position="756"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ25683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="768" mass="86794" checksum="B058758DE91DFB5F" modified="2011-01-11" version="1">MSRIRLIQPDGTEVDIEDTGNNHARNRPDLEAATSWRNNGGSPSTIPQDVPRGIPSDGQTEINDHGDTAQLKAETTKSESKVPRSSKDDISHVGGAPGLDDREPGMPFDVSESESELDYDDLWDSIDEQLIEPPPENGRKYLPLDQLRKIMVKPRVRQELKKLKGMDQDTIHRYANAVCDTTDYGTMQRTTRHKMFATLVHIEHIEALSSFIDEKIHDVHLPFILQKKPRWHLTYTTTDRTTNEKITAKFQGSYSWSKAKMNSFVDHQWLFMAPFFDMKANKPPFYPLEARVVLPFRKEEKCDPAYGGFSTVSRTHIHEAHHNSKHANRAAFERELHAMKKFNRQGHPHLMKLLATYQYQQHWYFIFPWANGNLREFWQQHHTPQPDHQLVVWIADQITGIASGLKLIQHPPKDPTLTQDARDSGRHGDLRPENVLWFRDHDKDKSIIGSGVLKIADFGLTSYHHHSSRYDNAKDVNFAQTYKAPEVDVAEEVSQPYDIWTLGCLLLEFVTWYLKGWQGVDEFSGDRAKNDAKEDEIPLDTFYNIIMVDGVKQAVLKPTVKELLTYISDHLLRIDPKKRQKCLDVANTMKQMAGDFKQNQEYAVSGCKPPNKSGTTEITRTEKTVPDYGHAETEFGTQTTLVGSRDPSPKRSEIPQDHDSVLPNSTKGHNGHVVYQNASIEYSIETPNTTTTKVIPIETQTVSNSGGETKQSDTIENGGGGDSKRRGGHSAGKRSTLWRNESTLVETGGGGGGGGEMHVMSPGRAYTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4L5</accession>
    <name>E3Q4L5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heterokaryon incompatibility protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_01174</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ26030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090050.1">
        <property type="nucleotide sequence ID" value="XM_008091859.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4L5"/>
    <dbReference type="GeneID" id="24406539"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01174"/>
    <dbReference type="eggNOG" id="ENOG502SKX3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003953_5_0_1"/>
    <dbReference type="OrthoDB" id="5135333at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF1">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="307"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="651"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="664"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="709"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="729"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="776"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="789"/>
            <end position="803"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ26030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1050" mass="119720" checksum="041AC16AF23717D2" modified="2011-01-11" version="1">MSVAEISHRTRPLSITSVMSDVAETPDRPAVRPRPLSDSGSSEQRRREIKDLCPVCQSLKLGVQSFKVQPGPPRASGVPSSGRMLHSSTTARRLGSLQGMEARSATCALCALIVRSVHKAGTQSPPANQAPDEGAGAQLQRATCFVSWEIDGREAASTGSPGRSPKNLVRGVTRRMHIRWNHPRLSDAYLVYVAPDTFLRTTSDADRVWVKDSLFLGRAISENIENQALIQSWLDLCRKNHKGPCCQIDDGRAERFIEMISHSYFGVIDVQNMQLTQLPCQSLPGPRGRRQPPYREAALDQVKPEPYVALSYVWGADPGAYTTRTENVMLHRTHGGLEEVLQKLPRAIQDAIDLARRLGFRYIWVDRLCIVQNSARSWKLNAYNMDLIYGNAALTICAADGDAGRGLCAMRPATRNTQQVKGLVGPRLELMVTRPPEMYIRASEWNERAWTFQERLLSRRCLIFTNGRVYFQCRSTGMSEDIFGDQRGAGWSLDLVDAPLQMFRQLDNRSIWVYMKCVELYTERKLTHDKDIQAAFSGMANLMEERMRAPFIHGLPSSHFDLALLWEPIKSGRRRVAEETPGNASIPDFPSWSWTGWVGEVQYKEDLVSGILDNVSDWLDTRTWIEWWVRDGHGDLRPLWDSRKSREDRSKEKKWRGYTQRRAARCEQRGRHHNEDEDGSVAPYDPDDAVIITRPDPYASPSESVQRSVEGRDNNYVERHDDSDDDENDRLISYRENSRDTKARGHDMRRPSRMSGGGPFQASKEPRDPYYHSRRPPPPPPPRPSRAPGRHEGHTSPRREYLRTRSPTRRRSGYYEENYYEEAVDGRRHHHHHMTQNRPVSVTPPPPVVVEYPRHNAEFFDMFFDGGRDNDDDFSITLRDYPYRVVKAPFDARPETAEHPLLPILQFRTWHAWLYIHDSGGAEQQQQQQQPQRGGAAAAAASTALGAGQVRHHIADEGGDWCGSIVLDAAWADGKPARQEFIAVSEAKSFTAAECREWTYYVPKERDQSEWDLFYVLLIERKDERWERVGVGKVFKEAFRGLKLKEIMLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4P8</accession>
    <name>E3Q4P8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Haloacid dehalogenase-like hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_01207</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ26063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090083.1">
        <property type="nucleotide sequence ID" value="XM_008091892.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4P8"/>
    <dbReference type="STRING" id="645133.E3Q4P8"/>
    <dbReference type="GeneID" id="24406572"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01207"/>
    <dbReference type="eggNOG" id="ENOG502REF4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_14_1_1"/>
    <dbReference type="OrthoDB" id="2107174at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008967">
        <property type="term" value="F:phosphoglycolate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050155">
        <property type="entry name" value="HAD-like_hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43434">
        <property type="entry name" value="PHOSPHOGLYCOLATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43434:SF1">
        <property type="entry name" value="PHOSPHOGLYCOLATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ26063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="281" mass="31226" checksum="54CCFD2292C0C9DF" modified="2011-01-11" version="1">MPQVSRFSNAKNGTQSFPAVSHMTDRLSNMFPKQQIKCILFDCDNTLVLSENAAFEACAQLANQILEKFGFEKRYGGTELMHQFVGQNFRSMMTGLCSRHGFTIPADEFDEWVAKELDTTIANLRAKAEPCENVIEVLEKLQKDGKYHMAIVSSSAMPRVVASIEKTKMDQFFGKPDEGIFSAASSINPPVSKPNPAIYLHACEKLGFKPSECIAIEDSRSGATAAKNAGIPLLGYVGPYYEEGQEKLDSMVKLFSEELGAFDVMHNWKDFESILAKYESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4Z6</accession>
    <name>E3Q4Z6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_01305</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ26161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090181.1">
        <property type="nucleotide sequence ID" value="XM_008091990.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4Z6"/>
    <dbReference type="STRING" id="645133.E3Q4Z6"/>
    <dbReference type="GeneID" id="24406670"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01305"/>
    <dbReference type="eggNOG" id="ENOG502SWQJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031200_0_0_1"/>
    <dbReference type="OrthoDB" id="5430717at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="312"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="363"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="473"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="142"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="327"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="363"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="483"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ26161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="494" mass="55256" checksum="11BB340206593CEC" modified="2011-01-11" version="1">MAELFLKPLQAQRRGPDMTSVQPDEYSLAHLDVLPFRSRQRRAVPRIASLDALSASKISGNACPSIRSDISQSSSHQMSPSPVEPNEIIWYRDQTQTEAPMSLDQMVDALHYIMMTKPVLDPVPREYNSYILHLLEGYWSVQEQLKKTKQALAEELETKQRSLEEFTKMSDEWQEKEADFRSEIKRMELVLAKIAPEGVGAVVMARSQSIVDRSAKSSKIFKAKIDKARSSPDRDVYGAFNLDSMETPRIPKVLENPHQTHRTLLSMQPKLDDNADVELSQELVKAQRKRQRVIKHTRQDMPVNPVDIVRTLDTSSSDEDTTLKPLQRTSESSTRPRTNQMSRQSSCIRRSEASYVSKFAISTPQEHDSLSQLPDNALGRTPSLSPAERGEAVTNIMAGGGSDRARPHVVTTVSNNQTEPFDRGPSGIHRHKRVFSFDPGDDDIPRQTCEAGAGAGSANGQRSYMHMAKSANIDQDHVLGRTVPSSSNSPDTQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q523</accession>
    <name>E3Q523_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ammonium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_00934</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089810.1">
        <property type="nucleotide sequence ID" value="XM_008091619.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q523"/>
    <dbReference type="STRING" id="645133.E3Q523"/>
    <dbReference type="GeneID" id="24406299"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00934"/>
    <dbReference type="eggNOG" id="KOG0682">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_33_0_1"/>
    <dbReference type="OrthoDB" id="534912at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3430.10:FF:000003">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="entry name" value="Ammonium transporter AmtB like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001905">
        <property type="entry name" value="Ammonium_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018047">
        <property type="entry name" value="Ammonium_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00836">
        <property type="entry name" value="amt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029">
        <property type="entry name" value="AMMONIUM TRANSPORTER MEP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029:SF10">
        <property type="entry name" value="AMMONIUM TRANSPORTER MEP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111352">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01219">
        <property type="entry name" value="AMMONIUM_TRANSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="183"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="231"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="292"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="315"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="344"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="398"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium transporter AmtB-like" evidence="10">
        <location>
            <begin position="38"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="461"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ25790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="482" mass="51340" checksum="55006F898D04DE64" modified="2011-01-11" version="1">MSAGLYALPYNGTEGRADAGYSSGVQDLNVFYESGDLAWIMVCAALVLLMIPGVGFFYSGLARRKSALSLILMSMICVGVVGFQWFFWGYTLTFSHTGSVFLGDMSNFGLRDVVAQPSVGSSKIPDILFCLYQGMFAAITPALALGAIADRGRILPAMVFAFIWATIVYDPIAYWTWNSKGWLFILGSLDFAGGTPVHISSGAAALAYSLMLGKRTGYNKVHGLPYRPHNVTHVVLGTVFLWVGWFGFNGGSALASNLRAVMACFNTNLAAGVGGVTWMLLDYRLEKKWSTIGFCSGAIAGLVAITPGAGFVTPWASVIFGIVGGSVCNFGTKLKFVLGIDDGLDIFAVHGIGGIAGNILTGIFAASYITALDGAYTGENAIAGGWIEHHYVQLGYQLAGSVAGFTWSFVLTCLILFLMNFIPGLSLRVNVDDEDLGLDDCQLGEFAYDYVEVTRHVSDISPNSHDGVPGSCADSSLPEKTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5C5</accession>
    <name>E3Q5C5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_01036</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089912.1">
        <property type="nucleotide sequence ID" value="XM_008091721.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5C5"/>
    <dbReference type="GeneID" id="24406401"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01036"/>
    <dbReference type="eggNOG" id="ENOG502R2ID">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_692623_0_0_1"/>
    <dbReference type="OrthoDB" id="4845392at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ25892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="398" mass="44388" checksum="E7C24B05930E1AAD" modified="2011-01-11" version="1">MASHVLAEGSMAIETGGTDKVVNNAAPDIISTVRNSNLLARDDVPPHDCEDILRRVITPEIDCSYSWENCGFDNHLEYRIRINAIGKTSPKWCEMMFHLVQRAINYHIRQEECDRTYRSNENGNGMVVVLTLPKPIAKFGEWRLRVEQAIKDNFCAGGPKLTYWVNERCYRTSICRHRWWKRSLGELSGNLPEVMSPAREIEPAFFSYAAPITATTVSVEPTTTNIVPRDEPPAIIVNQAAMAADSGVHSKIEEDVRPVGKCPDYTDVQHGCGSVDRSLISSVGVHCSYNRGQGNNINQLDYKVTINPTGQNTACWCDRLLAAVRARCPQGQADWAYPLLKCNTEHILTELGKGIHVNFHSNAWVAGKDNRECIKAAIESTTCGIATHFDRGGCFENH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5D5</accession>
    <name>E3Q5D5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Dcp1-like decapping family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_01046</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DCP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089922.1">
        <property type="nucleotide sequence ID" value="XM_008091731.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5D5"/>
    <dbReference type="SMR" id="E3Q5D5"/>
    <dbReference type="STRING" id="645133.E3Q5D5"/>
    <dbReference type="GeneID" id="24406411"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01046"/>
    <dbReference type="eggNOG" id="KOG2868">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058649_2_0_1"/>
    <dbReference type="OrthoDB" id="255837at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008047">
        <property type="term" value="F:enzyme activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000290">
        <property type="term" value="P:deadenylation-dependent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031087">
        <property type="term" value="P:deadenylation-independent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13182">
        <property type="entry name" value="EVH1-like_Dcp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010334">
        <property type="entry name" value="Dcp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16290:SF0">
        <property type="entry name" value="DECAPPING PROTEIN 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16290">
        <property type="entry name" value="TRANSCRIPTION FACTOR SMIF DECAPPING ENZYME DCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06058">
        <property type="entry name" value="DCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ25902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="240" mass="25902" checksum="88C63A52F8D35D64" modified="2011-01-11" version="1">MSRPTPRKRVHARHSSASGHGPRPVQSDYESDAAHYIDSHPVPAPNPALLNRTNTDLNLSVLRRYLPSINSTLSIAANAVVYTFNPSLPGWDKTGIEGTYFLCMQDPASAAVPAVPRACIFVLNRRGLENVILDLADVADFEVVDEIYIFRLRGAGGDEDEGSHNKVMGIWIHADKDDTRVMNAALIAETLKHVRAAGGDQNDPDGAAPTPQEELGPAMQAIGRRLSLSDLFGAQDGTKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6Z7</accession>
    <name>E3Q6Z7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">fumarate hydratase</fullName>
            <ecNumber evidence="2">4.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_02455</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the reversible stereospecific interconversion of fumarate to L-malate. In mitochondrion, catalyzes the hydration of fumarate to L-malate in the tricarboxylic acid (TCA) cycle to facilitate a transition step in the production of energy in the form of NADH. In cytoplasm and nucleus, involved in DNA repair in response to DNA damage: following DNA double-strand breaks (DSBs), translocates from the cytosol to the nucleus and promotes DNA repair by catalyzing the dehydration of L-malate to fumarate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.2" evidence="2"/>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090655.1">
        <property type="nucleotide sequence ID" value="XM_008092464.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6Z7"/>
    <dbReference type="STRING" id="645133.E3Q6Z7"/>
    <dbReference type="GeneID" id="24407820"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02455"/>
    <dbReference type="eggNOG" id="KOG1317">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021594_4_1_1"/>
    <dbReference type="OrthoDB" id="1738025at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004333">
        <property type="term" value="F:fumarate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006106">
        <property type="term" value="P:fumarate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd01362">
        <property type="entry name" value="Fumarase_classII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.40.30:FF:000002">
        <property type="entry name" value="Fumarate hydratase class II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.275.10:FF:000001">
        <property type="entry name" value="Fumarate hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.200.10:FF:000001">
        <property type="entry name" value="Fumarate hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.40.30">
        <property type="entry name" value="Fumarase/aspartase (C-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.200.10">
        <property type="entry name" value="Fumarase/aspartase (Central domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="entry name" value="Fumarase/aspartase (N-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00743">
        <property type="entry name" value="FumaraseC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005677">
        <property type="entry name" value="Fum_hydII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018951">
        <property type="entry name" value="Fumarase_C_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00979">
        <property type="entry name" value="fumC_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11444">
        <property type="entry name" value="ASPARTATEAMMONIA/ARGININOSUCCINATE/ADENYLOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11444:SF1">
        <property type="entry name" value="FUMARATE HYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10415">
        <property type="entry name" value="FumaraseC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="L-aspartase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumarate lyase N-terminal" evidence="5">
        <location>
            <begin position="83"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="Fumarase C C-terminal" evidence="6">
        <location>
            <begin position="482"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00056821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ26635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="541" mass="58198" checksum="7024FA90E6CBC99A" modified="2011-01-11" version="1">MLRSAPARRAASGLANSRLTVVPRTCATSLSTCSTRSATSSPAAIYPAMSRSSNFASPFSLQRSIHTTAPRMVETRTESDAFGEVQVPADKYWGAQTERSLENFKINQPQDRMPPPIVKAFGILKGAAAAVNMRYGLDEKIGKAIQQAAAEVAEGKLLDHFPLVVWQTGSGTQSNMNANEVISNRAIEILGGVKGSKKPVHPNDHVNRSASSNDTFPTVMHIAAVLEIENELIPSLKSLRDALQKKVDEFDAKQIIKIGRTHLQDATPLTLGQEFSGYVAQLDAGIKRVESSLPDLRLLAQGGTAVGTGINTFQGFAEAIAEEVTKMTGTEFKTAPNKFEALAAHDAIVQAHGSLNTVAASLSKIAQDIRYLGSGPRCGLGELILPENEPGSSIMPGKVNPTQCEALTMVCAQVMGNHVATTIGGMNGQFELNVYKPLVIRNLLHSVRILSDGMRSFEKNLVVGLQANEEKIASIMKESLMLVTCLNPKIGYDMASKVAKNAHKKGLTLKQSALELNALSEEDFDKLVRPELMIGPSPYKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q740</accession>
    <name>E3Q740_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_02498</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090698.1">
        <property type="nucleotide sequence ID" value="XM_008092507.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q740"/>
    <dbReference type="STRING" id="645133.E3Q740"/>
    <dbReference type="GeneID" id="24407863"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02498"/>
    <dbReference type="eggNOG" id="ENOG502RXHJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009769_1_0_1"/>
    <dbReference type="OrthoDB" id="283575at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17178">
        <property type="entry name" value="SECRETORY GRANULE PROTEOGLYCAN CORE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17178:SF0">
        <property type="entry name" value="SERGLYCIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="541"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="3 4">
        <location>
            <begin position="606"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="465"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="768"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="779"/>
            <end position="791"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ26678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="815" mass="86542" checksum="908B86A10EF19E6D" modified="2011-01-11" version="1">MENDPDSPTSVSEQQQPFQPPSSRIPRPQPPAALQNKFGGAGVAISRPTQIPQWPLGPISSPASNPDAEPYRPPLGRGPPPPRPPRPSRVPSILDSSRIQDHTPVFQYFPQPGRESVYSQDGQSAPPTPTSRHTQSSISSVGSIPDFPLPAIVPPIAAPPPVVPPRRSFGLGPPPSSRRGDSSFYSNASFVSPIPEESPRSRSHTSFASSAAMPESWGSQSPGYSEADPDDYYDDAYSSEDEDSQMSRGSGSPYGDVGDESKLVRSASVGKMSKPSIVMHRAPSGGDPLPQDVQGLPQRPSPSPMKLPVSPFDSGTAYYEGSSSSGTVPTMAGGGTPGSLTPNVMLGAVGAASATDLAETRKFTPSPRPYDRLSAVRRPPKLDMDSVREMESRGSMTSLPDLIKRATRLAALIDRGRRPASRFELDDGTWPDEKAFGREGEQPISTISSVEKHQSGLSDMLAAFPPPAATTPNPPNLPNRGSWFRRTSTTGSWPLAPGSQGSTPQPVTRAMAARGSPLTRLESNDEESSARRRRRCCGLPLWAFIVIVVIVLGIVAAAIVVPLEFLVFRRNRASNPPAEPALSQCQNQLKCENGGTNVISQGICSCICINGFTGQTCTVAGATGCTTTSLQGNGTPTSLSNVTLGQAIPRLLQQAQTNFSIPLDGTDILAKLNTENLSCIAQNSLVTFDGRSSRVGTDDGGIVNNAAVPVQIITLLPGQALTLTLGRRQLDHAGYDPDDVPITAADILYIAAADIFFNTAARDDDDDIFGAPSGSTNRSHHDYDESNDHNNHPGAARPLDPIVFSTTTQAYIYGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7H6</accession>
    <name>E3Q7H6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NUDIX domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02634</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090834.1">
        <property type="nucleotide sequence ID" value="XM_008092643.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7H6"/>
    <dbReference type="GeneID" id="24407999"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02634"/>
    <dbReference type="eggNOG" id="ENOG502S8JU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067850_0_0_1"/>
    <dbReference type="OrthoDB" id="276276at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43736">
        <property type="entry name" value="ADP-RIBOSE PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43736:SF1">
        <property type="entry name" value="DIHYDRONEOPTERIN TRIPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="37"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="243" mass="25477" checksum="19AE96D85008B034" modified="2011-01-11" version="1">MPPAPPSPPLSYTTAPAVLPYTLRFHPYRPSSSPNHTHRLCVGAAVLAPAPAATPRILLLRRSAREKSLPHRWELPGGGADAPDRDALAAAARELWEETGLRAARFVALVGCYQWEGAGPGIPATAVPGDQAWGLAGGGVGVGVVEASSAAAAAEGADATAAGAAGRDAWRKYTYLVEVEAPAGEEGAAAAEVVVDPEEHDAFVWATEEEVRAGRCGRVVFEWTSDAQRLDVLRAFEVASRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q867</accession>
    <name>E3Q867_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">von Willebrand factor type A domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_02250</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091099.1">
        <property type="nucleotide sequence ID" value="XM_008092908.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q867"/>
    <dbReference type="STRING" id="645133.E3Q867"/>
    <dbReference type="GeneID" id="24407615"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02250"/>
    <dbReference type="eggNOG" id="ENOG502QTWJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006368_0_0_1"/>
    <dbReference type="OrthoDB" id="299997at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.410:FF:000014">
        <property type="entry name" value="von Willebrand and RING finger domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051266">
        <property type="entry name" value="CLCR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10579">
        <property type="entry name" value="CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10579:SF43">
        <property type="entry name" value="ZINC FINGER (C3HC4-TYPE RING FINGER) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15411">
        <property type="entry name" value="PH_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="4">
        <location>
            <begin position="19"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="311"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="5">
        <location>
            <begin position="502"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="89"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="437"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="875"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="99"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="130"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="917"/>
            <end position="929"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ27079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1039" mass="113900" checksum="126FACDC906F93E2" modified="2011-01-11" version="1">MASGAGRNRRERTFVGSECAVCEEPLEHTLQGERILQFSCSHVSHEACFYEFIREFEAQYCPSCDAPLHLDTSRGGNVLDIEKISSLVKSSHSSDNRSNHTPTPTATQWDTPTPRPTSIESNQRNMASTHTRESAPRSSGRDRDSSQPATSERYGPSRHVRSDSEATGVASSGGYPETTQSGPPPRRHDYDVQAMETTPGSPRGITRNPIPAPTVTVRSEFPTINRSRQQQTLTCLITVEVPDNKWRPDPEDLGSAPPGLPVVNARIDDAFARPPSPARSAPRFYPYESREVLEEMTENLRNRVDNWHGLDFTRFGKLRLYGTLRVGKDKQSWQELECFLFAEMLICVKEKKVPLAGQWDENGMPKKAVRCTLKGSILIKKHLNEVSETGNIDENVLTLNLSVAELPQFHLRFENRNQLKLWHQALLDLNAVETSPVRSPEYDRGEFSETDEEDWQRVSRQQRVSSVASSWGGPKSVTTAPTEYTNFQRSPTMPTSIHVPIDVVVVVPISSSMQGVKINLVRDALKFMVNTLGERDRMGLVTFGSGGGGVPIVGMTTKAWPGWSNVLSSIKPVGQKSHRADVVEGANVAMDLLMQRKYNNPIATIMLISDASTSDADSVDFVVSRAEAAKITIHSFGLGMTHKPDTMIELSTRTKASYTYVKDWMMLRECLAGCLGAMQTLSHQNVKLKLKLPEGSPAKFHKISGALQITKRATGRDAEASLGDLRFGDKRDVLVQLVIVPDNTSQEQLPQDPWDNIVSGLEALGGTGDGDDQRITSVEEVPLIQADLTWGDILRDGTLSHLPRPSLLAITMLPALAKQKNSWANSPPIPPHPHIVQRRMELLTSDMLTRALTLVSRGQHDRAHTLLNETRSILKGLGKGGLPPIPPPTAPPNRSLPSTPHPGNDASPSITPDRKQTPSPTQSANSSAVNGYPAASIGRSRSNDGLGLGAGIDANTVAALDAELESSLEWISHPAVFGRDSRKAVLQAIGVISSQRAFTFRTPIESLWAGRVAGVKKLTSKSREWRDEGGGEGGIMEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8G0</accession>
    <name>E3Q8G0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_02343</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091192.1">
        <property type="nucleotide sequence ID" value="XM_008093001.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8G0"/>
    <dbReference type="GeneID" id="24407708"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02343"/>
    <dbReference type="HOGENOM" id="CLU_2812185_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ27172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="67" mass="7475" checksum="A1E53035EDBD0ACA" modified="2011-01-11" version="1">MDKEPNKLCWGRLLGKVIRSGKLWHYVPPEEGSPLKHPFAVLVSSSAYLTRSMACSKTVVTTVVFLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8J4</accession>
    <name>E3Q8J4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sin3 binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02377</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091226.1">
        <property type="nucleotide sequence ID" value="XM_008093035.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8J4"/>
    <dbReference type="STRING" id="645133.E3Q8J4"/>
    <dbReference type="GeneID" id="24407742"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02377"/>
    <dbReference type="eggNOG" id="ENOG502QW7S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037235_0_0_1"/>
    <dbReference type="OrthoDB" id="5391991at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000432">
        <property type="term" value="P:positive regulation of transcription from RNA polymerase II promoter by glucose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018818">
        <property type="entry name" value="Stb3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28164">
        <property type="entry name" value="PROTEIN STB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28164:SF1">
        <property type="entry name" value="PROTEIN STB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10330">
        <property type="entry name" value="Stb3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="347" mass="36507" checksum="F4B874C53C4C77DE" modified="2011-01-11" version="1">MATMAAAVRDIHQASDMGRDNLTVVAARSVPATTVTRSQALPTPPNSISPSLPPHGLKAQLQKASLELIDSDLDLHDDPSGLAREASRSPSYDATGSISTTLLAKHHLPEILLNHGPLAIRHIMGYLTTSVPGFAGIPPTKARRLVVGALEGRGAEGGGLDGDVEFEKVGWGRWDARRRGQPPRGSSPPTDYRSGIPINKSGGRGMDRSRLNLASSSAGDSVVFSHDDRDAMMMENEADKMSLDGSASASCSEAPDDDDIDMNDDPEDATDDEDWAAVGAAALRAESYNTAGATAQSAGRSFLGMRTVSTGMARSHQPLTFDFSAHGAPSDAQERDAVEALLRLGSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8K7</accession>
    <name>E3Q8K7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02049</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ26878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090898.1">
        <property type="nucleotide sequence ID" value="XM_008092707.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8K7"/>
    <dbReference type="GeneID" id="24407414"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02049"/>
    <dbReference type="eggNOG" id="ENOG502T4BE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1194806_0_0_1"/>
    <dbReference type="OrthoDB" id="4837986at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="232" mass="25481" checksum="17706FA93DE28B22" modified="2011-01-11" version="1">MSQPAGPSLRSKGKAIAKPDTQPPKDQSTPGRSAYGVPTINVLSTAISRGKPPTDLQTRSDFCFDRLLSFLPHDEHKLLRVYRALDVPSARLRKWASKGRKRLGQKVLARLEQQKDAAPGEYQFAVDHPYVWGLGNGDAWARAGQAYDLKLKGEPLRLPDKEAVMQEDIPGGAVNGASSPRPNKTSKYSRKRNRNALDDTNKVPGAHGRHTEFQKKKAAGIGPSPLRKSSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9T3</accession>
    <name>E3Q9T3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02765</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091641.1">
        <property type="nucleotide sequence ID" value="XM_008093450.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9T3"/>
    <dbReference type="GeneID" id="24408130"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02765"/>
    <dbReference type="eggNOG" id="ENOG502SX2P">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_163539_0_0_1"/>
    <dbReference type="OrthoDB" id="5232608at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="94" mass="9919" checksum="614390EBF32644E4" modified="2011-01-11" version="1">METSTAQSLIISLAVVVAVFLAGFFAYQQGMLDPVIEQIGIMLFKAKAEAEKKKMQAQGMKAGQDFVDGQLKGNKQAADVADGIGSVGGLKKQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QA00</accession>
    <name>E3QA00_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">WD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_02832</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091708.1">
        <property type="nucleotide sequence ID" value="XM_008093517.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QA00"/>
    <dbReference type="STRING" id="645133.E3QA00"/>
    <dbReference type="GeneID" id="24408197"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02832"/>
    <dbReference type="eggNOG" id="KOG1036">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038526_0_0_1"/>
    <dbReference type="OrthoDB" id="10262475at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10971">
        <property type="entry name" value="MRNA EXPORT FACTOR AND BUB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="258"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ27688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="351" mass="37944" checksum="B00A547F256A7BD4" modified="2011-01-11" version="1">MAPASQFELAQPPSDAISSLAYAPDSPTRLLVSCWDKKIYLYDTHSGGQDASGTLVQTIEFRAPVLDVTFGATDNEAYTACLDHCVYRVDLESGEKQVVSQHTAPARCVVYSPEHSLLISASWDQTLQIHNAKSPSDDNITVQLPGKPHALAASPSKVVVAMTARLVNIYDLGNIPSLFSQSGPHDIKPWQQRESSLKFLTRAVSCMPNDAGYATSSIEGRVAVEWFEDSAESQARKYAFKCHRQAAPDGEGDIVYPVNAMAFHPVYGTFASGGGDGTVALWDAEAKRRMKQYQKFPDSVAALAFSKDGKYLAVGVCPGFETGMEDYSAEGKASVFIRELGDTEAKGKGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QA18</accession>
    <name>E3QA18_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Probable electron transfer flavoprotein subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_02850</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 7">The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </cofactor>
        <text evidence="7">Binds 1 AMP per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="7">Binds 1 FAD per dimer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the ETF beta-subunit/FixA family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091726.1">
        <property type="nucleotide sequence ID" value="XM_008093535.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QA18"/>
    <dbReference type="STRING" id="645133.E3QA18"/>
    <dbReference type="GeneID" id="24408215"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02850"/>
    <dbReference type="eggNOG" id="KOG3180">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060196_0_1_1"/>
    <dbReference type="OrthoDB" id="276685at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009063">
        <property type="term" value="P:amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01714">
        <property type="entry name" value="ETF_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000011">
        <property type="entry name" value="Electron transfer flavoprotein subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000049">
        <property type="entry name" value="ET-Flavoprotein_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012255">
        <property type="entry name" value="ETF_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033948">
        <property type="entry name" value="ETF_beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21294">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN BETA-SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21294:SF8">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000090">
        <property type="entry name" value="Beta-ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01065">
        <property type="entry name" value="ETF_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Electron transfer flavoprotein alpha/beta-subunit N-terminal" evidence="8">
        <location>
            <begin position="26"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00070315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ27706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="258" mass="27786" checksum="FE2BF091DA69D392" modified="2011-01-11" version="1">MSALRILVPVKRVIDYAVKPRVNKAQTGVETAGVKHSMNPFDELSVEESVRIREKKRAPGGVEDITVISAGPPKAVDVLRTAMAMGADRAIHVETKEGDDLEPLSVAKLLRKAAEEHKSNLIILGKQSIDDDANQTGQMLAGLLGWSQATSASVVKFGEGDTVSVTREVDGGVETVKGKLPMVITTDLRLNEPRYASLPNIMKAKKKPLEKKKLADYGIGVEKRLKVLKVTEPPVRQGGGKVEDVNGLVAKLKELGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAC4</accession>
    <name>E3QAC4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Mannose-P-dolichol utilization defect 1 protein homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_02956</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the MPDU1 (TC 2.A.43.3) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091832.1">
        <property type="nucleotide sequence ID" value="XM_008093641.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAC4"/>
    <dbReference type="STRING" id="645133.E3QAC4"/>
    <dbReference type="GeneID" id="24408321"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02956"/>
    <dbReference type="eggNOG" id="KOG3211">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053568_0_1_1"/>
    <dbReference type="OrthoDB" id="271506at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.290:FF:000006">
        <property type="entry name" value="mannose-P-dolichol utilization defect 1 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016817">
        <property type="entry name" value="MannP-dilichol_defect-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12226">
        <property type="entry name" value="MANNOSE-P-DOLICHOL UTILIZATION DEFECT 1 LEC35 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12226:SF2">
        <property type="entry name" value="MANNOSE-P-DOLICHOL UTILIZATION DEFECT 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF023381">
        <property type="entry name" value="MannP-dilichol_defect-1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="222"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="250"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="257"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR023381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ27812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="287" mass="30349" checksum="C55D6B49262CFC8D" modified="2011-01-11" version="1">MDAVRSALQPITHNLPAPIRDLGVSIIGEQCYKSLLLDINVEDVDCIKLGLSKGVGLGIVGVSGIVKLPQIRKLTASQSGEGISVLSYLLETASYIVSLAYNYRNQFPFSTYGETALIMGQNVIITVLVLNYTRRAGLAAVFVTVLAAAVAALFTGNLVDMQTLGYLQAGAGVLSVASKVPQILAIWQEGGTGQLSAFAVFNYLAGSLSRIFTTLQEVDDNLILYNFIAGFLLNAVLAAQMAYYWNAPSKKAKGKQKVPVAAAPPSSGSSTATSTTPKKGPSTRRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAR1</accession>
    <name>E3QAR1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">LPXTG-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_03093</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ27949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091969.1">
        <property type="nucleotide sequence ID" value="XM_008093778.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAR1"/>
    <dbReference type="GeneID" id="24408458"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03093"/>
    <dbReference type="eggNOG" id="ENOG502SSVT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031222_3_1_1"/>
    <dbReference type="OrthoDB" id="5426678at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180269" description="LPXTG-domain-containing protein" evidence="3">
        <location>
            <begin position="22"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="367"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="402"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="529"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="372"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ27949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="548" mass="58878" checksum="8C27336CD1FF8EE1" modified="2011-01-11" version="1">MTVVSSWRLLAVFSLIAAVSSLEVTPGSDCAALCLDGHNGTAVDTSGTSSSDIVCENDQYHSTGTGIKFKNCISCLQNSQATKGPESDAAWFMYNVRYAVDVCLFNFPDAISDINSPCIINSACLPLKNALTSGLVAPEAGTAYDYCTADNDKFSSSSWWSCVRCLQSSDDQSYLSNFLIALKAGCQRKPTDGSLIGLTGQLFSEVAVNITDTATNTTMPGDGGASATSMTLGTIVGIAVGGGLVFVGAICLFIIYCRKQRKQKAQDGGYLDQRPPGSNGSSVTATSKSHYIPIADHKKSSSIRSYNYELQEKQNVIHSNADYYDRLAQEVQAGREMAHYNFDPHSGHHGPGSALPTHPAYIPRAMSRQSHRTNTPTPPNLRRTNTPDSYALQTYLNAVENPAVSAIRPPPQAASRTPSPARSQRSYTDNPALPQLANIPPPPPGGPPSRKQSRSIPSLSLPSVPRIRVPKQYSPPQIVVEGATPVDDRGETGAMHISEPLTHHGERFQDRPLAGRPIISYVAPVRDIDPQDYESDIPIRSGKSTLYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QB80</accession>
    <name>E3QB80_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alpha-L-rhamnosidase six-hairpin glycosidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_03262</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ28118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092138.1">
        <property type="nucleotide sequence ID" value="XM_008093947.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QB80"/>
    <dbReference type="STRING" id="645133.E3QB80"/>
    <dbReference type="GeneID" id="24408627"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03262"/>
    <dbReference type="eggNOG" id="ENOG502QWE4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007933_3_0_1"/>
    <dbReference type="OrthoDB" id="10036721at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.420.10">
        <property type="entry name" value="Maltose phosphorylase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035396">
        <property type="entry name" value="Bac_rhamnosid6H"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34987:SF6">
        <property type="entry name" value="ALPHA-L-RHAMNOSIDASE SIX-HAIRPIN GLYCOSIDASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34987">
        <property type="entry name" value="C, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G02880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17389">
        <property type="entry name" value="Bac_rhamnosid6H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180277" description="Alpha-L-rhamnosidase six-hairpin glycosidase domain-containing protein" evidence="2">
        <location>
            <begin position="25"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-L-rhamnosidase six-hairpin glycosidase" evidence="3">
        <location>
            <begin position="312"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ28118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="815" mass="89300" checksum="E646FAAD4B88EF25" modified="2011-01-11" version="1">MKPTTPVAEWASLALLFAPPTALAALRPPFIDPGALPTTSIFKGPWESYIKAPADKTRIVPARIWDAKGNVTTSGLGEVEVGAKAADAFGHGVTVGPGGVLTLEFEENIAGRVCFDVSSAGNEPEIYLAYSESLLYAGPQPDTTTEKLERDLPLHFEFDDTTGTVCVGKEFLRGAFKYLTLSMPEYPVIADDRVVEQPSPDGQVVFAGDRSDSEEGHRGPSGRDPYKKPWVTLRNLWVNCTAFPSQPNGRAYSGYFHSSNPMLNRIWYAGAYTLQLSTIDPREGSALIDYNRDWDHNESPKGSWYSNFTIANGTAVTTDGAKRDRVVWPGDMSIAIPGIAVSTYDMLAVRNALDVLFDHQYPDGSLPYAGPPLGFRREFSDTYHLHTLLGAYNYVKYSGDVDWLARRWPAYLKALDVSIGKVDRTGLLHVTSGADWLRPGMTGHNLEASALLSAALDKSIRLAEWLRDDRPAARPHGVWSVARARLNAGIQQLFCKDTGLYSDNIGRRGCRGPEHTDPQDGNSWALISGAAPQYRRAVVSENLRSRWTRHGAPAVEFPNVISPFVSSFELLGHAAADNHDAAVELMLLEWSYLLDGPGFTNSTLAEGFMVDGGVQYPAYRSAARNSHCHGWSSGPTSVLTSEVLGIRLLAPAGAEWTVRPHLSKWLGFARGGFATTKGPFEVKLTRVVASTSSAAPANQKRRRRGQVIEVTTPALTHGSFEWGPSSHKVEVEGGQPAAWVVWDDDASVEQLDVSLGRVEAPSEEEWYRQSFIYRDDTRLVYDDTWAPPPMAERPAGEVDWDALEANYAGPLAEMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBA4</accession>
    <name>E3QBA4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Mitochondrial aspartate-glutamate transporter AGC1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Aspartate-glutamate carrier 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">GLRG_03286</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Calcium-dependent mitochondrial aspartate and glutamate carrier. Transport of glutamate in mitochondria is required for mitochondrial transamination reactions and ornithine synthesis. Plays also a role in malate-aspartate NADH shuttle, which is critical for growth on acetate and fatty acids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homodimer (via N-terminus).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ28142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092162.1">
        <property type="nucleotide sequence ID" value="XM_008093971.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBA4"/>
    <dbReference type="STRING" id="645133.E3QBA4"/>
    <dbReference type="GeneID" id="24408651"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03286"/>
    <dbReference type="eggNOG" id="KOG0751">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014931_2_0_1"/>
    <dbReference type="OrthoDB" id="2161at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015183">
        <property type="term" value="F:L-aspartate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005313">
        <property type="term" value="F:L-glutamate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043490">
        <property type="term" value="P:malate-aspartate shuttle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000004">
        <property type="entry name" value="Calcium-binding mitochondrial carrier protein Aralar1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000552">
        <property type="entry name" value="Probable mitochondrial carrier protein ARALAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051028">
        <property type="entry name" value="Mito_Solute_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45678:SF9">
        <property type="entry name" value="CALCIUM-BINDING MITOCHONDRIAL CARRIER PROTEIN ARALAR1"/>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR45678">
        <property type="entry name" value="MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER 1-RELATED"/>
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    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="10 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="EF-hand" evidence="16">
        <location>
            <begin position="104"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="16">
        <location>
            <begin position="176"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="15">
        <location>
            <begin position="349"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="15">
        <location>
            <begin position="447"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="15">
        <location>
            <begin position="545"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00059916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00073787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00082232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EFQ28142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="708" mass="78690" checksum="3A0A2271CDFFD147" modified="2011-01-11" version="1">MSKAAVVKEAVKEAVKESLLGAEEPVQLSAQTKARFIANAAKDEATGELFMGPEEFTKAVAPENEDFHKIKREQYGILFGVADRKGVGKITLSEWAAFENLLMKPDAEYEIAFRLFDVDRTGNVKYEDFRKLYELNKGPDSIPFDWECEWAKLYIGSKKKRHHMDYPQFSQMLRGLQGERIRQAFQLFDKDGDGFIDPEDFERIILETSKHKLSDHLLENLSTLCNISLGSKVSYANVRAFQNMIKEIDLVELIVRRACAKSPDGKITRTEFLNQAAKITRFSLFTPMEADILFHFASLDEPSGRLGLGDFAKVLDPSWRNAIYDADDAASRALAKSATASKAVLTSILESAYNFGLGSMAGAFGAFMVYPIDLVKTRLQNQRSARPGERLYKNSIDCFQKVWRNEGPRGLYSGVVPQLIGVAPEKAIKLTVNDIVRAYFTNKEGKIWYGHEILAGGAAGGCQVVFTNPLEIVKIRLQVQGEVAKTVEGAPRRSAMWIVRNLGLVGLYKGASACLLRDVPFSAIYFPTYSHLKRDFFGESPTKKLGVLQLLTAGAIAGMPAAYLTTPCDVIKTRLQVEARKGEATYTGLRHAAKTIWKEEGFRAFFKGGPARIFRSSPQFGFTLAAYEVLQNVIPYPGKPESSKVHTGVGDAVSTLKKNLDTSPFARSRNALKIILDIDEDFGKVKVPNQESWKKLPAFMQTNGNGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBG7</accession>
    <name>E3QBG7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sedlin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_03450</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092326.1">
        <property type="nucleotide sequence ID" value="XM_008094135.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBG7"/>
    <dbReference type="STRING" id="645133.E3QBG7"/>
    <dbReference type="GeneID" id="24408815"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03450"/>
    <dbReference type="eggNOG" id="KOG3444">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083394_0_0_1"/>
    <dbReference type="OrthoDB" id="18320at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006722">
        <property type="entry name" value="Sedlin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12403">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04628">
        <property type="entry name" value="Sedlin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ28306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="202" mass="21229" checksum="57CCDD2ECFBD7EEC" modified="2011-01-11" version="1">MAATIPSIACIGIIGRNNNPLNIQIFPSHNPATNTFAPIRTPLQFSLLLSSTLDVFELRHGNGTSGNGGGAAVGSSGTGLSGEVGLLHAVDERLAAYGWETNTGVKIVVVVDMRGRRVAGAGSAAAEAAAKGRGAVGLREQELRVVFRAVQNAYVRLLQNPFYEPDEHAPVSGRGGRVIKSKKFEGEVRRIGETWTPGVTSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QD72</accession>
    <name>E3QD72_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Beta-lactamase superfamily domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_03988</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092864.1">
        <property type="nucleotide sequence ID" value="XM_008094673.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QD72"/>
    <dbReference type="STRING" id="645133.E3QD72"/>
    <dbReference type="GeneID" id="24409353"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03988"/>
    <dbReference type="eggNOG" id="ENOG502S7AM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047435_2_0_1"/>
    <dbReference type="OrthoDB" id="332863at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36142:SF5">
        <property type="entry name" value="METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36142">
        <property type="entry name" value="METALLO-HYDROLASE/OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13483">
        <property type="entry name" value="Lactamase_B_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="354"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="423"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ28844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="451" mass="49048" checksum="7E90426A8E6FC04A" modified="2011-01-11" version="1">MALTVKQLNADASFLLTFEPIVPESTPGITARPFRVLLDPWITGPSTMFHSILATATHKECPCVCSLQHLPEPDLVIISQHKSDHCNEATLRQLPASGTRTLILAEPAAAKIIRSWKYFDADKVHTVPRWEDPRATGKKQSVVRVKVPPFSPGGEPGEVTVAFIPQRRDFKGLHAAIGITYRPPPTWPRFPHLSTPPETPVSQQLSLIRSQVAMASHKKSRNAPVYLSPPTPPETPSSRSLRSVRSGTLATPIPDARDRAVSVIFSPHGISYRCLEKYADTHLKAEAALPLTALLHCFDTVSNPWWLGGNISTGMPAGQETAAALGATAWVSTHDGDKDVKGLVTKMLKTKRYTQKQVAAPSSSGQKRGDRHGRWEKTGDGEKEGKGTEVLVLGVGEEVAMTGEGVWNVESAARALPMSWKLPEIGKTPKGRERGRGLAPVDTAAKYGPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDN3</accession>
    <name>E3QDN3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ABC-2 type transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_04115</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ28971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092991.1">
        <property type="nucleotide sequence ID" value="XM_008094800.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QDN3"/>
    <dbReference type="GeneID" id="24409480"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04115"/>
    <dbReference type="eggNOG" id="KOG0065">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_35_0_1"/>
    <dbReference type="OrthoDB" id="245989at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03233">
        <property type="entry name" value="ABCG_PDR_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000054">
        <property type="entry name" value="ABC multidrug transporter atrF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029481">
        <property type="entry name" value="ABC_trans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034001">
        <property type="entry name" value="ABCG_PDR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034003">
        <property type="entry name" value="ABCG_PDR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010929">
        <property type="entry name" value="PDR_CDR_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14510">
        <property type="entry name" value="ABC_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06422">
        <property type="entry name" value="PDR_CDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="492"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="527"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="569"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="605"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="638"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="747"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1167"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1200"/>
            <end position="1221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1242"/>
            <end position="1267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1287"/>
            <end position="1307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1319"/>
            <end position="1338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1438"/>
            <end position="1458"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="125"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="825"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="790"/>
            <end position="815"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ28971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1473" mass="165011" checksum="BBD95B46A13D2D51" modified="2011-01-11" version="1">MLAPGFPGPGPAAAEPHITRFDSDTTLVISSDADEVAEGEIQDLAKRLTSASHGGVHSLFPEPSDATIDPRDPEFDARKWAAAFHRLQTKALHGNAPNTVGLAFKNLHIYGLGTTRDYQKTVGNFFLEAAARLVQSRKKQQIDILHNVEGVIQSGEMLAVLGPPGSGCTTLLKTIAGETHGFYVADGATLNYQGISPDEMNTTFKGEAIYTAEFDHHFPFLTVGETLYFAARARCPQNMALPDGISKHKYAEHLRDVVMALLGISHTKDTRVGDDFVRGVSGGERKRVSIAEAVLSYAPLQCWDNSTRGLDSANAIEFCHTLRMQSDVFGFSSAVSIYQAPQEAYDLFDKVIVLYEGRQIFFGKTTDARPYFESLGFRCPEQKTTADFLTSMTSSSERVVHPDWKGQTPPRSPDEFARAWQASEHRRRLLVEIDEFEHEFPFGGNTSKQFSATRRVHQSKRQRPSSPYTLSFSQQIILNLWRSSRLLISEPWMTITMLTTNCFESLIISSIFYNLPPNSSSIYKRLLLIFYAILINAMGSILEVLTLYGKRKIIEKHARYALYHPSAEAVAAMVVDLPYKLVNSLFINVPIYFMTNLRRDSTGPFFFFLLLSFSTTISMSMIFRFLGSVTKTMAQALAPSAIILLGLILFSGFSIPQAYLSDWMGWIRWVNPVFYVQESLALNEFVGRNFSCSDFVPSGLNYDTSSARSNERVCGIGGAVPGSNSINGEDHLRVVYGFVNGHRWRNFGIVVAITVIFMTMYLVAVELVSSERSKGEVLLFNRRTLKNVKRGPNDDENLGGNQPYPVIEKSEDSDSSGLAKQTSVFHWKDVCYDVQVKGETRRILDRVDGWVKPGTLTALMGVSGAGKTSLLDVLASRVTMGVVGGEMLVDGHLRDSSFQRKTGYVTQQDLHLHTATVREALNFSAFLRQPRQYSREEKLAYVDTVIDLLGMQEYADAVIGELGEGLNVEQRKLLTIGVELVARPQLLLFLDEPTSGLDSQTSWSICDLMERLTKSGQAILCTIHQPSASLFQRFDRLLLLAKGGQTVYFGDIGKNSHVLLDYLGRHGAPGYQPGSNPAEYMLEVIGAAPKAHTDIDWPNVWRKSEEYQSVQSELRRLSEHKSHNDARQTTETHDTLAHEEFAADFRVQIHEVTKRVFQQYWRSPSYIFSKSIVTCGSALFIGLTLLGGDNTKRSLKNQMFGVYTFLFIFSQVVQQIMPVFVSQRTMYEARERPAKSYSWKAFMAANVIVEIFWNSIMAVFSFLLWFYPMRLDRNAEWTDAVQSRAVTFFLICWVFFLFSSTFAHLMIAGLGSAEVAGGIMNLAFILMFALCGVLAGPHELPGFWIFMYRVNPFTYLMDAFLSTGVANAPVKCSPTELLIFDAPSGRTCGEYMAEYIQNNGGYLVNNNASKCQFCDMADTNTFLSDMNMSFDNRWRDFGLIWAFCVFNIVAAAALYWVTRVPKNDFKKRSPSNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDT1</accession>
    <name>E3QDT1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DUF1680 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_04163</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093039.1">
        <property type="nucleotide sequence ID" value="XM_008094848.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDT1"/>
    <dbReference type="STRING" id="645133.E3QDT1"/>
    <dbReference type="GeneID" id="24409528"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04163"/>
    <dbReference type="eggNOG" id="ENOG502QYM6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013148_3_0_1"/>
    <dbReference type="OrthoDB" id="654211at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049174">
        <property type="entry name" value="Beta-AFase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049049">
        <property type="entry name" value="Beta-AFase-like_GH127_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012878">
        <property type="entry name" value="Beta-AFase-like_GH127_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049046">
        <property type="entry name" value="Beta-AFase-like_GH127_middle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43465">
        <property type="entry name" value="DUF1680 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G08910)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43465:SF2">
        <property type="entry name" value="DUF1680 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G08910)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07944">
        <property type="entry name" value="Beta-AFase-like_GH127_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20737">
        <property type="entry name" value="Glyco_hydro127C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20736">
        <property type="entry name" value="Glyco_hydro127M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Non-reducing end beta-L-arabinofuranosidase-like GH127 catalytic" evidence="1">
        <location>
            <begin position="20"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="Non-reducing end beta-L-arabinofuranosidase-like GH127 middle" evidence="2">
        <location>
            <begin position="454"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="domain" description="Non-reducing end beta-L-arabinofuranosidase-like GH127 C-terminal" evidence="3">
        <location>
            <begin position="556"/>
            <end position="660"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ29019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="667" mass="75187" checksum="BB91EB2DEA36D6A1" modified="2011-01-11" version="1">MSNPQIVFRQTTFTAPSLLLSRRRIISRTTVHAQLDQLRANGQYDCFKLVWHPIYDDKSRWPAPLHLFWDSDVAKWIEGACYFLADEYDVEVDAAVRELVEMIRGAQHDDGYLNVHFSVVEPGKRWTNIRDMHEMYNAGHLIEAALAHSQYYRNDRLMEPIEKYIAHIRRRFGPGDGQLRAYPGHPEIELALLRFYSVTGLRDAYDLARFFLEERGSPAGQDGKHFYDWEAEQRDEPRWKRPNSWPMDRSYWYCQAHAPILQQPAVEGHAVRAMYLLIAAADLLNLSQTSAPSAELRPLAAAADWLAALRRLWSNMVDKKMYLTGGVGAVAQWEGFGIDYFLPQGPDEGGGYAETCASVGVMMLAERLLHADPTLDGRYADVMELCLYNNVMTAMSLDGKAFTYENQLASCAAAPSEREDWFWCACCPPNVTRLFGSLGGYLWDYGGGEGTASVNVHLYTSAEVRFPAGEAEVTLSQESNWPWEGRVSFRLGGAQGLETKIRLRIPAWANGGFTLTPAPPPGTSALERGYLHLSPAYTAANAAFTLDVDGFAPRYVAPHPYTNQRTLSLARGPVVYCVEDADHPWERNHFKDMALKRGGEVEEEWRVDPGSGEGYFALKTVGWERSPEALERGEGGIRRELVFVPFYFRANRGGKGQMRVGLRDDGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEF7</accession>
    <name>E3QEF7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TBC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_04407</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093283.1">
        <property type="nucleotide sequence ID" value="XM_008095092.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEF7"/>
    <dbReference type="STRING" id="645133.E3QEF7"/>
    <dbReference type="GeneID" id="24409772"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04407"/>
    <dbReference type="eggNOG" id="KOG2058">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029367_3_0_1"/>
    <dbReference type="OrthoDB" id="10263206at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044732">
        <property type="term" value="C:mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031030">
        <property type="term" value="P:negative regulation of septation initiation signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.80:FF:000026">
        <property type="entry name" value="Mitotic check point protein (Bub2)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957:SF263">
        <property type="entry name" value="MITOTIC CHECK POINT PROTEIN BUB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="2">
        <location>
            <begin position="141"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="228"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ29263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="443" mass="48883" checksum="5400B5A9D395314C" modified="2011-01-11" version="1">MTTELLPPPSPRTHRLRKLQSAHNLGSKAALQLQPQHQPSLIAQQRLTQRNISPTRRDPSASSTMVRHTRGRSNSDAPAPVAHHMTAMASSKRSMMGINPKYATMSLQQLIKEGPPNGDTVEALGMARRKVLSEGIKSDSDGMSTLRIYVWLILLDTPILPTDDYLGLIHRGASPAYSKIRNDTFRTLTTDPLFRRRVSEASLIRLLNAVAWRLHDSREEQRRERPSTGRSSISQDSSTSTATAHSQNPASSPSARNRARALTLTTEGSETSHAGEPGTYVQGMNVLAAPFLYAARSESEAFIAFYTLLTRECPGYIRGAMDGVHKGLALVDKVLATVDSKLSGYLHSKGLTAEIYAFPSVLTLCACTPPLPEVLRLWDFLFAYGPHLNILCIVAQLMGMRDHPNKLLRSFPSLQADKVIERTLWIVERIPDDTYAAIVAHAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEP9</accession>
    <name>E3QEP9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_04499</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the proteasome complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the peptidase T1B family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093375.1">
        <property type="nucleotide sequence ID" value="XM_008095184.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEP9"/>
    <dbReference type="STRING" id="645133.E3QEP9"/>
    <dbReference type="MEROPS" id="T01.P02"/>
    <dbReference type="GeneID" id="24409864"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04499"/>
    <dbReference type="eggNOG" id="KOG0180">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035750_10_0_1"/>
    <dbReference type="OrthoDB" id="204949at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061133">
        <property type="term" value="F:endopeptidase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010499">
        <property type="term" value="P:proteasomal ubiquitin-independent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd03759">
        <property type="entry name" value="proteasome_beta_type_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000003">
        <property type="entry name" value="Proteasome subunit beta type-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033811">
        <property type="entry name" value="Proteasome_beta_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF10">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA TYPE-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 5 6" id="KW-0647">Proteasome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00026071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ29355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="205" mass="22475" checksum="5BBB19C46FA6A074" modified="2011-01-11" version="1">MSSPFSINGGACVAMVGKDCVAIACDLRLGLQALTVSNNFPKIFQYGDVFLGLTGLATDVTTVGDLFRYKVNMYRLREERNIAPTTFANLVSSSLYERRFGPYFVSPVVAGLDPKTGKPFICGFDSIGCIDFAKDFIVSGTASEQLFGMCESLWEPDLGPEELFETISQSLLNAVDRDALSGWGAHVYIIEKDKVTKRLLKGRQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QF25</accession>
    <name>E3QF25_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04607</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093483.1">
        <property type="nucleotide sequence ID" value="XM_008095292.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QF25"/>
    <dbReference type="GeneID" id="24409972"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04607"/>
    <dbReference type="eggNOG" id="ENOG502T4BZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1686449_0_0_1"/>
    <dbReference type="OrthoDB" id="4846786at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="165" mass="18384" checksum="695E3DEB0AF81D84" modified="2011-01-11" version="1">MCCRRRRAARQAWLEQRAAGGGKCGRSRGWGTGPGPDGPSSRPPFTGGRRAFRRWQDAPREDAHQESLHYQQATTPRNDPTTKDIEKATPAVEPKASRVPFTFGPLGWRRNSMGTDADRALKRESTMSLPPRYKFGVPEVPQRSDDGAVAKRESLPPDYTASTKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>E3QF47</accession>
    <name>E3QF47_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Palmitoyltransferase</fullName>
            <ecNumber evidence="11">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_04629</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DHHC palmitoyltransferase family. PFA5 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="11"/>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093505.1">
        <property type="nucleotide sequence ID" value="XM_008095314.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QF47"/>
    <dbReference type="STRING" id="645133.E3QF47"/>
    <dbReference type="GeneID" id="24409994"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04629"/>
    <dbReference type="eggNOG" id="KOG1315">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034009_0_0_1"/>
    <dbReference type="OrthoDB" id="331948at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883:SF23">
        <property type="entry name" value="PALMITOYLTRANSFERASE ZDHHC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883">
        <property type="entry name" value="ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0564">Palmitate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="193"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="228"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="13">
        <location>
            <begin position="143"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="86"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="280"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="380"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="289"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="391"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ29485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="403" mass="45687" checksum="8E9F2068692C8CD2" modified="2011-01-11" version="1">MSQATSTKCASRWVTRIIPITITGTSGYATYVIVAYLGVDYLYRTRGEVGAAVSTITIYLFFYLLTIATYLRTFIKIKMDPGLVPLGPQAQHPSRESNKKRRRRKEGDLESQPYFTGPDQDPDSPGLETFYSKDVFVCESDGRPKWCSECRNWKPDRAHHSSEVGRCVRKMDHYCPWVGGMVSETSFKFFAQFTFYCTLYCAIALAQAAYCLALQARDGTVDGRTISGVAIAAFFGLFTFLMTATSWRFIFLNITNIDALRKSWVHQLAIRVPNGTRPGNHDGTITYPLPNSSREVQTSSNATADSETPRDRLATRTFAIVRTEPDENPWDLGYTRNWISVMGHSWLDWLLPIHGSPCTNHESMESDYEMGSLIQTLRERHGLTDPNQPSREMEMQEMRPGDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFC6</accession>
    <name>E3QFC6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Outer spore wall protein RRT8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_04708</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093584.1">
        <property type="nucleotide sequence ID" value="XM_008095393.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFC6"/>
    <dbReference type="STRING" id="645133.E3QFC6"/>
    <dbReference type="GeneID" id="24410073"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04708"/>
    <dbReference type="eggNOG" id="ENOG502QVX4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062645_0_0_1"/>
    <dbReference type="OrthoDB" id="10012223at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005619">
        <property type="term" value="C:ascospore wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005628">
        <property type="term" value="C:prospore membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059112">
        <property type="entry name" value="CysZ/EI24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052786">
        <property type="entry name" value="Spore_wall_assembly"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34292">
        <property type="entry name" value="OUTER SPORE WALL PROTEIN LDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34292:SF2">
        <property type="entry name" value="OUTER SPORE WALL PROTEIN LDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07264">
        <property type="entry name" value="EI24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ29564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="305" mass="33618" checksum="2F5EEF64403D33E6" modified="2011-01-11" version="1">MSDERTVSEGQSSRPGARNRVVDSVHAKAQEVLAEDYDKARILVTDAAKSKAYLYPIKGIVYFATHQTLWKPLLSRIGSYLLLSAGVVTGMFVFTYVPQLAILVFVNGPLAVFTTVLLILSESSAIINFVSRSYLLQEAILDTFDGTLLLRGEDGIVREGRQVGSGSDPMQKLGKVLKNPFEKYSPKALIRYLIYLPLNFIPVVGTVIFIALQARSRGQAVHGRYFQLKNWSSSRRKDWLQKHSGPYTAFGLVATALEMVPFASVIFTFTNAVGAALWAADIEDKDTSMTDGTAPTLRETAKKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFM7</accession>
    <name>E3QFM7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Non-reducing end beta-L-arabinofuranosidase-like GH127 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_04809</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093685.1">
        <property type="nucleotide sequence ID" value="XM_008095494.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFM7"/>
    <dbReference type="GeneID" id="24410174"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04809"/>
    <dbReference type="eggNOG" id="ENOG502QRCI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008033_2_0_1"/>
    <dbReference type="OrthoDB" id="5358475at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012878">
        <property type="entry name" value="Beta-AFase-like_GH127_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31151">
        <property type="entry name" value="PROLINE-TRNA LIGASE (DUF1680)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31151:SF0">
        <property type="entry name" value="PROLINE-TRNA LIGASE (DUF1680)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07944">
        <property type="entry name" value="Beta-AFase-like_GH127_cat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179693" description="Non-reducing end beta-L-arabinofuranosidase-like GH127 catalytic domain-containing protein" evidence="1">
        <location>
            <begin position="29"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="Non-reducing end beta-L-arabinofuranosidase-like GH127 catalytic" evidence="2">
        <location>
            <begin position="47"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="Non-reducing end beta-L-arabinofuranosidase-like GH127 catalytic" evidence="2">
        <location>
            <begin position="256"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ29665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="436" mass="47960" checksum="9362FFEA2E5FE57C" modified="2011-01-11" version="1">MWSKTGILPGLAALALTVGLSSTGNAQAVPPVGQDQGVSAWGFDMSQVTLSTGRFFDNQARTLVYLKWIDVDRLLYVFRKNHGLYTNNAQPNAGWDAPDFPFRSHVQGHFLNAWAFCYAQLQDSECKRRATYFAAELKKCQHNNTNSRNVPYYAIHKTMAGLLDVWRLIGDTNARDVLLAMAAWVDLRTGKLTYQQMQDMMGTVFGGMNEVLADLCRQTGDQRWVTVAQRFDHAAIFNPLASNQDSLSGLHANTQDIARNAWNITVSAHSYAIGGNSQAEHFRLPNAIAGFLTSDTCEACNTYNMLKLTGELWLTNPDTTTYFDFYERALLNHLLGQQDPSNSHGHVTYFTPLNPGGRRGVGPAWGGGPVILNGNYCNEILSTTPALDLATVKRSGATGLAFTATAGGKTVNLGQFYDAQGFNYNVYWSVNGKLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFN3</accession>
    <name>E3QFN3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Probable methionine--tRNA ligase, mitochondrial</fullName>
            <ecNumber evidence="2">6.1.1.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_04862</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>tRNA(Met) + L-methionine + ATP = L-methionyl-tRNA(Met) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13481"/>
            <dbReference type="Rhea" id="RHEA-COMP:9667"/>
            <dbReference type="Rhea" id="RHEA-COMP:9698"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78530"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.10"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.10" evidence="2"/>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093738.1">
        <property type="nucleotide sequence ID" value="XM_008095547.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFN3"/>
    <dbReference type="STRING" id="645133.E3QFN3"/>
    <dbReference type="GeneID" id="24410227"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04862"/>
    <dbReference type="eggNOG" id="KOG0436">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009710_9_0_1"/>
    <dbReference type="OrthoDB" id="24670at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004825">
        <property type="term" value="F:methionine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006431">
        <property type="term" value="P:methionyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07957">
        <property type="entry name" value="Anticodon_Ia_Met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00814">
        <property type="entry name" value="MetRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.220.10:FF:000001">
        <property type="entry name" value="methionine--tRNA ligase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041872">
        <property type="entry name" value="Anticodon_Met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014758">
        <property type="entry name" value="Met-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023457">
        <property type="entry name" value="Met-tRNA_synth_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033911">
        <property type="entry name" value="MetRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00398">
        <property type="entry name" value="metG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43326:SF1">
        <property type="entry name" value="METHIONINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43326">
        <property type="entry name" value="METHIONYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19303">
        <property type="entry name" value="Anticodon_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01041">
        <property type="entry name" value="TRNASYNTHMET"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 13" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methionyl/Leucyl tRNA synthetase" evidence="11">
        <location>
            <begin position="11"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl-tRNA synthetase anticodon-binding" evidence="12">
        <location>
            <begin position="406"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00068817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF09334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF19303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ29718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="545" mass="61714" checksum="5D36643FDD8A9310" modified="2011-01-11" version="1">MSSDSKGDKPYYVTTPIFYVNASPHIGHMYSMILADVLKRWQVLKGRPAILCTGTDEHGSKVQQAAARQGVEPKDFCDTTAEKFRDLARAIGMDNDHFIRTTDPDHKEAVQHFWHLLKGKGYIYEAKHQGWYCISDECFYAADEIERKVVPRTGRTAMVSIESGNEVEWIEEKTYHFRMTALKDRLLEFYTANPDWIVPRARMNEVIAWVSNNLEDLSISRPVQRLDWGVRVPDDPSQTVYVWVDALINYLTKAGFPGWQPGREHEGGWPADVHVIGKDIVRFHGVYWPALLMALDLPLPKQLLTHAHWTLGRKKMSKSLGNVVNPFFAIDRWGLDTMRYFMMRDGGIEKDADYENSFILERYQKDLQSTLGNSMNRVAKSKVWKLRNSVAWVGQNGIFRGHAVNGSDALKASVNEMAATMSEHMDQLNPNAAIRSVLSVLAEVNKYLTDTGPWNLYRSTKATDQAELHEIIYHASEAVRCAGILLQPVMPAKMGTMLDILGVQVDKRGFEHAVFGADLTYGTPMIDPGRPGDWNSLFPPPAAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QG13</accession>
    <name>E3QG13_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">t-SNARE affecting a late Golgi compartment protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">GLRG_04992</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093868.1">
        <property type="nucleotide sequence ID" value="XM_008095677.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QG13"/>
    <dbReference type="STRING" id="645133.E3QG13"/>
    <dbReference type="GeneID" id="24410357"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04992"/>
    <dbReference type="eggNOG" id="KOG3202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061883_0_0_1"/>
    <dbReference type="OrthoDB" id="546861at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048193">
        <property type="term" value="P:Golgi vesicle transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21444">
        <property type="entry name" value="SNARE_NTD_Tlg1p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15851">
        <property type="entry name" value="SNARE_Syntaxin6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.90:FF:000012">
        <property type="entry name" value="SNARE domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000006">
        <property type="entry name" value="Syntaxin 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015260">
        <property type="entry name" value="Syntaxin-6/10/61_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048036">
        <property type="entry name" value="Tlg1p-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12791">
        <property type="entry name" value="GOLGI SNARE BET1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09177">
        <property type="entry name" value="STX6_10_61_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="14">
        <location>
            <begin position="167"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="116"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="51"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="118"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00073343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EFQ29848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="259" mass="28732" checksum="D00E16D01EBE89AA" modified="2011-01-11" version="1">MMSSANEEDPFLQVQQDVLAQLNSTRPLFTSYLRIRSLSTSPTSPELASARSDLESALESLAEDLADLVESVKAVESDPSAFGLSAQEIIRRKRLVQDVGGEVEDMREELFKKLGDVSSSSRGKSGAARGANSDLPDPSSFSITDGDDDHDRGGEDYAAEFEQQQQLEMMREQDTHLDGVFQTVGNLRRQADDMGRELEEQREMLEVVDSVADRVGGRLQTGVQKLQYVMRRNEDRLSSCCIAVLIFVLIVLLVLLLML</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>E3QG97</accession>
    <name>E3QG97_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Fungal specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_04837</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093713.1">
        <property type="nucleotide sequence ID" value="XM_008095522.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QG97"/>
    <dbReference type="STRING" id="645133.E3QG97"/>
    <dbReference type="GeneID" id="24410202"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04837"/>
    <dbReference type="eggNOG" id="ENOG502QYWX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004083_5_2_1"/>
    <dbReference type="OrthoDB" id="2269373at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF85">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="15"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="77"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="112"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ29693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="722" mass="81535" checksum="D37A2944B645B569" modified="2011-01-11" version="1">MSTNPNHNKSQRVLACVLCQHRKIKCDRNTPCSNCIKANVTCTPSTPAPARKRRRPNQDLQERLARCEALLKQYATASATPPTAHSPTIFNTPSSTGPSPSIPQLPLPSGSASVSEDTSPSTTSWKPAGKVVVEDGSVRFMDSYLWATVHDQLSAMRQIIEAEEEEQSVLGSDAVTPDDNVDLLLNDVATIDLEDVTPSPVQIFRLWQVFLERVNPITKLIHVPSLQPLVVEAAANHSNVANNCQALLFAIYLVASLTMTESEARQMLDISREEALKKFTAGVKAALTKVNFLKNHDLMTLQALLLYLISLQGRYSRHAAWVLSGILIRIAQKMGLHRDGELLNLTPYETEMRRRLWWQIIMLDTKYALVSGFSDTLLPWNWDTQTPQNVNDADLFPGSTEPVQPREGPTEMVFCLLLYEVGRFIVENRIPDFEAVVLGAMENDTQDSQLALQASLAKYRTLVDNLDAKLIALEKQYCDPLAGNIHIVATKIRSMIIDKLRTMMIPMRELPEWGTEVFNVQDNMFRISLVHHEHNVELYSFMENTGFVWFFKLHFQIDVFIVMAGQLFQRPTGKLAERAWRVVDRIYQYHEELWDMSKKENTQLGVYMLKAWRARERALIQIGLPYETPVAIPRLQEIVPQSSSEASSCGPSPAQTVKADIPQRQDQPMDQYLGNFLDTTNFYDLDMWADLGVPNGNMNQQSTANMFEQFGNFGVPPANRGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGF1</accession>
    <name>E3QGF1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_05083</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ29939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093959.1">
        <property type="nucleotide sequence ID" value="XM_008095768.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGF1"/>
    <dbReference type="STRING" id="645133.E3QGF1"/>
    <dbReference type="GeneID" id="24410448"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05083"/>
    <dbReference type="eggNOG" id="ENOG502T1TD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015630_1_0_1"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053083">
        <property type="entry name" value="TF_kinase-domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44305">
        <property type="entry name" value="SI:DKEY-192D15.2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44305:SF24">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE C03B1.5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="137"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="530"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="533"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="556"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ29939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="616" mass="68821" checksum="F68D9A6ACACECBBC" modified="2011-01-11" version="1">MGQWWDAARIDATVTRKFVCQYLLPEEIERLDRPLAFGDGLTDETYWDWIDNKAKRIFLILVDLKIPDQIFGIIDDSWDDHDLPISSEHVERLRLTAVKDDKIERKFFARQFNYLLKPFQRGDHISFNEYELVPLEVVERRPAGNNTVDKVILPNCPGLIFYRRRIPLGNGVGQLPRSEFVEIINSIKGIQNDHLVSYHASYTQLGAAYVLFTPATDSNLKSFFGNTPSNFKNLPKRERRHAVMNWILCLADTLAYLHSRRLCHGNIKPSTILFTSQLHIFYSDFTRLNAEVLAVYTDKNSFDRESYDYAAPEQWFRPTGGPASPLGRGAAAFSVSTSPETQTNFSIPRNDNPSSPNAMLNMPNPYLNPQAADIFSLGCVILDLMSFLVKKTTKSFSAHRAAKHKTPGRGGAVLDSSFHKNLGQVESWMSALAKEASKKVSASDGGYVFRGIVPLMHIVARMLSANPIDRPSAAEVQTQVYQILTKHCDITEPHCVHQYGGWDFGISNLRIQAVSPNAQFMPQPIRHNSMLQSSRRGSDSLSGSISPRGLSHSRTNSSGGMSNNSGISSAASERDQERDAGTGFTAVRNIRLPAVRSPAPWDSTVQGGRGDQAPVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGJ6</accession>
    <name>E3QGJ6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05128</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ29984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094004.1">
        <property type="nucleotide sequence ID" value="XM_008095813.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGJ6"/>
    <dbReference type="GeneID" id="24410493"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05128"/>
    <dbReference type="eggNOG" id="ENOG502T4AX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_182417_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="71" mass="7994" checksum="AFA1C99FEB0637D8" modified="2011-01-11" version="1">MGQFDWFRSIGATPEAVAVLNDQPILFTILLVALLAIILECVLLWYIHFATLKPEQQKKKEPRKGAKGGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QH04</accession>
    <name>E3QH04_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_05286</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ30142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094162.1">
        <property type="nucleotide sequence ID" value="XM_008095971.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QH04"/>
    <dbReference type="STRING" id="645133.E3QH04"/>
    <dbReference type="GeneID" id="24410651"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05286"/>
    <dbReference type="eggNOG" id="ENOG502RPSV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092485_0_0_1"/>
    <dbReference type="OrthoDB" id="4849325at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="79"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="62"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ30142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="194" mass="21971" checksum="465D62EDD0D115CB" modified="2011-01-11" version="1">MDLQQGADCDISDYMHTEYHSLPGQQDEPASSSSHYSDAQEYEEPTPVAGSSRATKQKHKSSPSTKKASAKGSPPKQPVQCDWEGCGRWFPRLTELRKHAKKNHLPPSIPCKARNAPTFLGMPPCEMMFYENKDMYRHVRNAHPLFAADSTNGIPPEGGPCPVCREWIARDDNLKRHIDEQHKDMQRRGRQRCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHE9</accession>
    <name>E3QHE9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_05455</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EFQ30311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008096140.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="24410820"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05455"/>
    <dbReference type="HOGENOM" id="CLU_1810724_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ30311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="143" mass="16331" checksum="9335F4CD95BB0C00" modified="2011-01-11" version="1" fragment="single">VIPVQRLNYPPQLNWRWLRIVCEPTSARSPLPGTSAQCCRLGVAAVISPQSKWNIPSSAHQAHLLLSREYSASGMVQHQPTPYTQTVRTWLRSAHDMWFLIYELSVQIEIHIQKTRLPTFRGIKRPDLPGAMPHPFEEGLQTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIZ0</accession>
    <name>E3QIZ0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05972</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094848.1">
        <property type="nucleotide sequence ID" value="XM_008096657.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIZ0"/>
    <dbReference type="STRING" id="645133.E3QIZ0"/>
    <dbReference type="GeneID" id="24411337"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05972"/>
    <dbReference type="eggNOG" id="ENOG502SFYT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048596_0_0_1"/>
    <dbReference type="OrthoDB" id="1681166at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="108"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="135"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="291"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="353" mass="36589" checksum="8CD9A750636780DB" modified="2011-01-11" version="1">MTPNSSSFRPSLHPIAESPTAASISPREKDATDRDARHLVSNNALSRRPRPDRPPPPPAPSRRLPSKRHAAPLELFRLMMPDVPTSPRPEADQPATASLSSSLQHQKAPLGSSPGAAAPSATAPDPAPDADPDADTAAAAEPGTEPAPKLDPAGFFTLVSNATTNSTHHPTVKYIFLDDDPDTLTAALAAHHAANQAAPTPSASTSKPAAPGGKNPPPSAVDRAVLLDVVPGADGQWTVASAASLSADFAVTDASIARQEGEKEGGLVLKIEGVESEGAAGGDKDRDRAESLPSSSSAVARSGGEEYGPLLEDFERKMSVLRRVVKAGEGRAEKAREKKPASDDTGPKQETEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJ05</accession>
    <name>E3QJ05_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_05987</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
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        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094863.1">
        <property type="nucleotide sequence ID" value="XM_008096672.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJ05"/>
    <dbReference type="GeneID" id="24411352"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05987"/>
    <dbReference type="eggNOG" id="ENOG502S67X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041445_0_1_1"/>
    <dbReference type="OrthoDB" id="3205825at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35179:SF1">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35179">
        <property type="entry name" value="PROTEIN CBG02620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="62"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="374"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="440"/>
            <end position="459"/>
        </location>
    </feature>
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        <location>
            <begin position="378"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ30843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="459" mass="52338" checksum="97C591D991DE2343" modified="2011-01-11" version="1">MSNLLSPHFKLEEVSENDIVIASLAWGFTLGFGWLTVWTAIKQTTAMYKRQGRRMHRNAYIWMIWLEIIVCAIFSVICWLYLRGIIPPSFEFYFSILTTWALQQVQFLLQIIINRCAILLDNPKHSLRLKVGVAVLITAVNISVYNIWIPARLQTSDRYIKINDWWDRCEKIIYLIVDGALNIYFVRIVQKNLVTHGLTKYKRLTRFNMFIIGFSLSMDVLIIAMMSLKNTFVYMQFHPLAYMVKLKIEMSMAELIGKVASKRDLSVLSAQNFEASRGSYQPSEYSLPSPSYPRGQQFGNIDVTLNSIDRNPVELTMPCTRAPKLRGANVAAVSSGPSDRRASVTASTMTEDGQPRMAIYRTREVVVEVEAVRDEGHQATTSQTSQAGLDDAHKTNKHEDDSYVKNLGTVQKSLALPEYHAPWATQEFCPKIWDGTNYDEDPNLPTSAAKVDAQWQNRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJ16</accession>
    <name>E3QJ16_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05998</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094874.1">
        <property type="nucleotide sequence ID" value="XM_008096683.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJ16"/>
    <dbReference type="GeneID" id="24411363"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05998"/>
    <dbReference type="HOGENOM" id="CLU_2426889_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="91" mass="9925" checksum="1A7705DAD14F83C0" modified="2011-01-11" version="1">MQKGTNAFIFHSSVVSRLTGRDDLHYVKYPQYSPDFGRLRLLPIIDNAGHRLIAIIGDIGGGAAWGIMALLTSVYSKAWAAVAMAFAFVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJF3</accession>
    <name>E3QJF3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_06135</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ30991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095011.1">
        <property type="nucleotide sequence ID" value="XM_008096820.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJF3"/>
    <dbReference type="STRING" id="645133.E3QJF3"/>
    <dbReference type="GeneID" id="24411500"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06135"/>
    <dbReference type="eggNOG" id="ENOG502T3G9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1234921_0_0_1"/>
    <dbReference type="OrthoDB" id="4793776at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ30991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="231" mass="26077" checksum="10CF4399B9F5113D" modified="2011-01-11" version="1">MAVISRLSQLTEDQKRMCDDLLTVLIQRNHPIDPPTLEEVREEFWTRVFKSNWTTSNLNIAPVKLPKRTNDESALLIGTLNQNVPKNGSVPGYRRSDQPVLLKVSMKIDPQLDVPVASFFWVDQQGHRGSELSNASIDIEGDLTLDEAKVEVGLHYDTNEKERVGGWNWSKVTYWGRARLINIAQGIITAAGEDVEELKPVRLVQEHWMHTEDSPQNSLSQVDGLEGVVNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QK74</accession>
    <name>E3QK74_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alcohol acetyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_06406</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697354">
        <property type="protein sequence ID" value="EFQ31262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095282.1">
        <property type="nucleotide sequence ID" value="XM_008097091.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QK74"/>
    <dbReference type="STRING" id="645133.E3QK74"/>
    <dbReference type="GeneID" id="24411771"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06406"/>
    <dbReference type="eggNOG" id="ENOG502RC91">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024469_0_1_1"/>
    <dbReference type="OrthoDB" id="2150604at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052058">
        <property type="entry name" value="Alcohol_O-acetyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010828">
        <property type="entry name" value="Atf2/Sli1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28037">
        <property type="entry name" value="ALCOHOL O-ACETYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28037:SF1">
        <property type="entry name" value="ALCOHOL O-ACETYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07247">
        <property type="entry name" value="AATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ31262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="477" mass="52227" checksum="48E9566279740592" modified="2011-01-11" version="1">MKSQAAPSREKYSTARHSLGLYRCVSVTCRYAVPPGTGLEELKMELRRAIAQVIMEQPFMRVGIVDEDKQAPYYVHVSRIDLTAQIQWYGPSHPDAADAALCKHLSFQHDQLWPHVGQRPPWKIAIIPIETIQASPVQIEVVYSFHHAIGDGTSGSIFHKRLLDALSNPVTVAGLDANQLNLPEPPVLPRPQDQLVDGRISWSYFLWELWDAFGPSWLKTKPEIVPWTARAIDFSMPYQTSVRILRVPAATAAGLLAASRAHSMTLTPLLHALVAASLSRHLPASEASSFNPSSAISLRRFVPASTGLDVDNQFSILVTSTDHLISESLTTNMRKPSDQTLEQAIWDAAASVRKELRDRLVTLPHDDITAMLKYVSDFHEFFTVKDGSERGNSWEVSNLGAISGGAIEGGWKLTRAVFSQSAMTAGPGFAVNVAGIAGGEVTVTLTWNESSIDAALMESLATDLQAWTQHLAAGIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKC7</accession>
    <name>E3QKC7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10">M-phase inducer phosphatase</fullName>
            <ecNumber evidence="2 10">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_06459</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 15">
            <text>O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10684"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="EC" id="3.1.3.48"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the MPI phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2 10"/>
    <dbReference type="EMBL" id="GG697354">
        <property type="protein sequence ID" value="EFQ31315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095335.1">
        <property type="nucleotide sequence ID" value="XM_008097144.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKC7"/>
    <dbReference type="STRING" id="645133.E3QKC7"/>
    <dbReference type="GeneID" id="24411824"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06459"/>
    <dbReference type="eggNOG" id="KOG3772">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017900_0_0_1"/>
    <dbReference type="OrthoDB" id="26523at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000086">
        <property type="term" value="P:G2/M transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010971">
        <property type="term" value="P:positive regulation of G2/M transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110032">
        <property type="term" value="P:positive regulation of G2/MI transition of meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01530">
        <property type="entry name" value="Cdc25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.250.10:FF:000021">
        <property type="entry name" value="M-phase inducer phosphatase cdc-25.2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000751">
        <property type="entry name" value="MPI_Phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10828">
        <property type="entry name" value="M-PHASE INDUCER PHOSPHATASE DUAL SPECIFICITY PHOSPHATASE CDC25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10828:SF17">
        <property type="entry name" value="PROTEIN-TYROSINE-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00716">
        <property type="entry name" value="MPIPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 10" id="KW-0498">Mitosis</keyword>
    <keyword evidence="6 10" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="12">
        <location>
            <begin position="370"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="139"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="232"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="302"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="139"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="196"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="264"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="304"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00051722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00067190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU368028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ31315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="563" mass="62766" checksum="F51C69C836AC75AD" modified="2011-01-11" version="1">MESSSPLAAMHRPMSVPCWGNKDLFRPRPHAFVGGAGPVSLREQLHRPGDYFNVKDVHGSSPAASLAADLSQNFRLDSESSPKFPTPRRALFTSNMTGDMESNDYVTTPPMPESSPAHHEMMDVSPLPHKLPFMTHISITSPTPGSTPTGDEDDEMMLDSPAPIPRQASLEPPKPLAAERRKPGMRRPSLTRMKGYSTSGVPGRSNTDNQLPTFRLGENRLAHMNSAMSLGECFDATSPPQERRPQTANSPTPAVPGAVRPRHQFSSLSGNRSSPFGSAHGRRPSNPFMRPRKQYRRSLSMFEHPGDVVKSKSEGDDSSPTTPESHASMDADDVQEPLLPHFLLDDPTDTIPRITRETMIDLLDGKYSEKFDQKMIIDCRFEYEYDGGHIDGAVNYNSKDLLASQLFKHPMQGRTILIFHCEYSAHRAPMMARHVRSEDRTVNAEHYPRLTYPDVYILEGGYSGFFAEHRCRCYPQNYVEMSDEAHQRTCERELGRLKNPRKGFGRAQTFAFGESCGVDQSPTAPSRPGGLRPSVSFRQDPIAMIGNSPILGERCHARRMASY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKE4</accession>
    <name>E3QKE4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TPR domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_06476</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697354">
        <property type="protein sequence ID" value="EFQ31332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095352.1">
        <property type="nucleotide sequence ID" value="XM_008097161.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKE4"/>
    <dbReference type="STRING" id="645133.E3QKE4"/>
    <dbReference type="GeneID" id="24411841"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06476"/>
    <dbReference type="HOGENOM" id="CLU_1626912_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ31332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="163" mass="17611" checksum="8DB33575E6DA3150" modified="2011-01-11" version="1">MFCYDKDIALTAFDRSEEAEVAQAKFEVAREAVPISHPSHLPTLGPGLPPIGSPMLPEELEYRKVVFEAAFEILREAPFHPALGVRLLEQGHAEQAEIGYRKDLGASRKAGNDDETTMVKRGRDIALASADVPIAASCFRAATAVRCTPNGTGCPNMGGMRET</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKI2</accession>
    <name>E3QKI2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_06514</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697355">
        <property type="protein sequence ID" value="EFQ31370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095390.1">
        <property type="nucleotide sequence ID" value="XM_008097199.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKI2"/>
    <dbReference type="STRING" id="645133.E3QKI2"/>
    <dbReference type="GeneID" id="24411879"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06514"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_9_0_1"/>
    <dbReference type="OrthoDB" id="1933717at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05324">
        <property type="entry name" value="carb_red_PTCR-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045313">
        <property type="entry name" value="CBR1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43963">
        <property type="entry name" value="CARBONYL REDUCTASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43963:SF6">
        <property type="entry name" value="CHAIN DEHYDROGENASE FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G15350)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ31370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="242" mass="25884" checksum="BEB7CE28B7B9525A" modified="2011-01-11" version="1">MIIALVTGGNSGIGEAVVRQLAKTPDFRVIIGSRNAESGLKLADSLSQEGGHSVSSVQLDLVSDESIFNAVKHIEDIYGRLDVLVNNAGILIDRRPDAFTTTRDLFRKTFETNVFGTAVLSEAALPLLLRAEYPRIIFVSSTMGSLEVSLDETTPFYHTDYKAYDASKAAVNMLAVNYARLLKDTGGASNAVCPGLVKTKLAGYHDYGTSVEIGAERIVSLATTSPGGPTGTFSNRQGPIPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3QL78</accession>
    <name>E3QL78_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Eukaryotic aspartyl protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_06905</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase A1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697356">
        <property type="protein sequence ID" value="EFQ31616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095636.1">
        <property type="nucleotide sequence ID" value="XM_008097445.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QL78"/>
    <dbReference type="STRING" id="645133.E3QL78"/>
    <dbReference type="GeneID" id="24412270"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06905"/>
    <dbReference type="eggNOG" id="KOG1339">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013253_0_1_1"/>
    <dbReference type="OrthoDB" id="2747330at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF2">
        <property type="entry name" value="ASPERGILLOPEPSIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180572" evidence="4">
        <location>
            <begin position="18"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="5">
        <location>
            <begin position="103"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ31616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="446" mass="48015" checksum="22B4CAF460002801" modified="2011-01-11" version="1">MLLSLVVPLLWSVMAHAIPTGPPASGPQPGTLPSSTFTIPVRANPDYVPDGAALAAAYEKWNMPVPEALAKHTLTRRSGYYCKFPSTPLLSSIVAARATGNFWLTDVFVGNPENPQKIPVIIDTGSSDFWLMTTDTKFGDKAAKGLPILYDPSKSTSSQEVSGATWSVSYGDGVTNSGKVYLDTVRFGLLTDNNRFNIINATIQSVVNVGQRWAVEPQISGVLGIAKNRPSSVQPSRPSMLDLLKPELHFEWIGIDLRHESNKGFFSFGYAMGTASINEKPMDSEEGWSFQISKTRMSTMDGGVWFRFSSPFTAIIDTATSFLMLPPSLVVKYYSEIPDSALDPDLGLYIFPCSLASGIPDFQFISAGGYVGTVPKEHINLGPVPGNTDKCYGGIQKSSDANRVIFGSVALKSMYVQLNYGAQGSYVGFGDKGSLDVCSATSACDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLL0</accession>
    <name>E3QLL0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_06723</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697357">
        <property type="protein sequence ID" value="EFQ31748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095768.1">
        <property type="nucleotide sequence ID" value="XM_008097577.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLL0"/>
    <dbReference type="STRING" id="645133.E3QLL0"/>
    <dbReference type="GeneID" id="24412088"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06723"/>
    <dbReference type="eggNOG" id="KOG2084">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028281_6_1_1"/>
    <dbReference type="OrthoDB" id="1028014at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053185">
        <property type="entry name" value="SET_domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332:SF6">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180583" description="SET domain-containing protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="3">
        <location>
            <begin position="142"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ31748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="432" mass="47015" checksum="2013AB629DD35D1B" modified="2011-01-11" version="1">MVLSSSAAALLPLAAALASYAVASETQAPLRWAQTCPWTPLDESLLECSIWDLTTAETKGEEKDLDQERRRTNGTTDPEPEPVGWTGPHGCAGNYCLYANRGFADGRGIVIISTPENVQKVRDLEQNLQSQPLEEDPSSGAPPFEIKEVEGKGLGMIANKTLARGDNVMLKTPVLLAHRAFIERTPAADRHALLDAVAGFLPPATRAGFLSQMGHFGGHQVSDIMATNSFQMDVGGGAQDDGHHYGNYPEVSRYNHDCRPNVAFRIGADLRHRTTVVRPVKPGEELTIAYLDPLATRSVRQHRAKRAWGFECGCSQCGLAKKQAAASDARLLEIEELDRLLSDVSAMVTSATVERFLKLHAEERLEAKLAGAYTTAALNFNLLGKNKMAAKYARLAVEAGTIENGSESEDVEAMKALAADPKKHFTWRGRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLR8</accession>
    <name>E3QLR8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lecithin:cholesterol acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_06781</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697357">
        <property type="protein sequence ID" value="EFQ31806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095826.1">
        <property type="nucleotide sequence ID" value="XM_008097635.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLR8"/>
    <dbReference type="STRING" id="645133.E3QLR8"/>
    <dbReference type="GeneID" id="24412146"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06781"/>
    <dbReference type="eggNOG" id="KOG2369">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016065_1_0_1"/>
    <dbReference type="OrthoDB" id="190846at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032541">
        <property type="term" value="C:cortical endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005637">
        <property type="term" value="C:nuclear inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097038">
        <property type="term" value="C:perinuclear endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046027">
        <property type="term" value="F:phospholipid:diacylglycerol acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006672">
        <property type="term" value="P:ceramide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140042">
        <property type="term" value="P:lipid droplet formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055091">
        <property type="term" value="P:phospholipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003386">
        <property type="entry name" value="LACT/PDAT_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11440">
        <property type="entry name" value="LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02450">
        <property type="entry name" value="LCAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ31806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="659" mass="74000" checksum="C1746068AA660356" modified="2011-01-11" version="1">MSSSTLRRRALPVDPQVDSEPSTPRDESPEKSENTTHVVHHVKPKTRKRRNGAIFLLGSLFGIIAAGFFAKSNDLIDFPELGELSMDSLFDVLPAGLVKDMRDLVVSNTSYMSFEGDLAPSWPELTWLLVKQGEREFVDSYDAFSVGLQARAEGLHAHHPMIMVPGVISTGLESWGTANVSRQYFRKRLWGSWSMMRALVLDKENWKRHIMLDQETGLDPPHIKLRAAQGFDATDFFITGYWIWNKIFENLASIGYDPTNSFTAAYDWRLAYPNLEIRDQYFSRLKSYIETAHEFSGKKAVLISHSMGGQVLFYFFHWVASETGGRGGDDWVERHVEAWINVSGCMLGAVKDLTAVLSGEMRDTAQLNAFAVYGLEKFLSKDERAQLFRAMPGISSMLPIGGDAVWGNSTWAPDDLPGQDSSYGSLLNFRSGMNWTTPDRNLTVESAMDYLFNTTEEWYSRKVKEAYSHGVAHTEAEVEANEKNPQKWINPLETRLPLAPSLKIYCFYGVGKPTERGYYYRSPEMPALTNLNITIDTALTQGEVDHGVVMGEGDGTVNLLSTGYMCNRGWNYKRYNPAGAKVTVVEMEHEPERFNPRGGPKTADHVDILGRQHLNELILRIAAGKGNTISDYVVSNILEYADKVKVYDDGEGPALEEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMG2</accession>
    <name>E3QMG2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07194</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096070.1">
        <property type="nucleotide sequence ID" value="XM_008097879.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMG2"/>
    <dbReference type="GeneID" id="24412559"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07194"/>
    <dbReference type="HOGENOM" id="CLU_1938007_0_0_1"/>
    <dbReference type="OrthoDB" id="4850566at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="130" mass="13121" checksum="8DB04223F93B566C" modified="2011-01-11" version="1">MAECGFITTAFPSGAVPTQPPILAPAESGTDTSPPPSPASPTMTSFPPAVATTTTQGPDLESITPVTVFETPSFSALPPLVLPNDISSTPPVLEQNENQLSGAARGLDTAFGGWLGRGVVFAVVVGLISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QN09</accession>
    <name>E3QN09_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">4-hydroxybenzoate polyprenyltransferase, mitochondrial</fullName>
            <shortName evidence="11">4-HB polyprenyltransferase</shortName>
            <ecNumber evidence="11">2.5.1.39</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Para-hydroxybenzoate--polyprenyltransferase</fullName>
            <shortName evidence="11">PHB:PPT</shortName>
            <shortName evidence="11">PHB:polyprenyltransferase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_07391</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 11">Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 11">
            <text>an all-trans-polyprenyl diphosphate + 4-hydroxybenzoate = a 4-hydroxy-3-(all-trans-polyprenyl)benzoate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:44504"/>
            <dbReference type="Rhea" id="RHEA-COMP:9514"/>
            <dbReference type="Rhea" id="RHEA-COMP:9564"/>
            <dbReference type="ChEBI" id="CHEBI:17879"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58914"/>
            <dbReference type="ChEBI" id="CHEBI:78396"/>
            <dbReference type="EC" id="2.5.1.39"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="11">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite biosynthesis; terpenoid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Mitochondrion inner membrane</location>
            <topology evidence="2 11">Multi-pass membrane protein</topology>
            <orientation evidence="2 11">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the UbiA prenyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.39" evidence="11"/>
    <dbReference type="EMBL" id="GG697360">
        <property type="protein sequence ID" value="EFQ32247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096267.1">
        <property type="nucleotide sequence ID" value="XM_008098076.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QN09"/>
    <dbReference type="STRING" id="645133.E3QN09"/>
    <dbReference type="GeneID" id="24412756"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07391"/>
    <dbReference type="eggNOG" id="KOG1381">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034879_2_0_1"/>
    <dbReference type="OrthoDB" id="18170at2759"/>
    <dbReference type="UniPathway" id="UPA00213"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008412">
        <property type="term" value="F:4-hydroxybenzoate polyprenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13959">
        <property type="entry name" value="PT_UbiA_COQ2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1780:FF:000001">
        <property type="entry name" value="4-hydroxybenzoate octaprenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.357.140:FF:000003">
        <property type="entry name" value="4-hydroxybenzoate polyprenyltransferase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1780">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01635">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006370">
        <property type="entry name" value="HB_polyprenyltransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039653">
        <property type="entry name" value="Prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030470">
        <property type="entry name" value="UbiA_prenylTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01474">
        <property type="entry name" value="ubiA_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11048:SF28">
        <property type="entry name" value="4-HYDROXYBENZOATE POLYPRENYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11048">
        <property type="entry name" value="PRENYLTRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00943">
        <property type="entry name" value="UBIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="11" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="297"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="326"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00052313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00058997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ32247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="365" mass="39153" checksum="603D7CCAE3D1936D" modified="2011-01-11" version="1">MALTLRNSSYQQAALHTSTERLTTAATQEVPEPPASPEAVYSPPKTGIISYLPASWVPYAELTRMDKPAGTYYLFFPCLWSTLMAAPMVAPMASPVSVIGTSLLFFSGAFIMRSAGCSINDLWDRKLDPHVTRTKFRPIARGALTPFQGLAFTGAQLLAGLGILLQFPTSCLFYGIPSLLLVASYPLAKRITYYPQAVLGLTFSWGAMMGFPALGIDLLSNSAALTAAACLYSSNVAWTVLYDMIYAHMDIKDDAKAGIKSIALKHDAETKQVLTGLAAVQLSLLSAAGFAAGAGPAFFIGSVGGAAVTLGVMIKRVKLKSVKDCWWWFVNGCWITGGVVSLGLAADYTVRYIQDGEEDVKTQEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QND2</accession>
    <name>E3QND2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">H/ACA ribonucleoprotein complex subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Nucleolar protein family A member 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_07514</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Common component of the spliceosome and rRNA processing machinery. In association with the spliceosomal U4/U6.U5 tri-snRNP particle, required for splicing of pre-mRNA. In association with box C/D snoRNPs, required for processing of pre-ribosomal RNA (rRNA) and site-specific 2'-O-methylation of substrate RNAs. Essential for the accumulation and stability of U4 snRNA, U6 snRNA, and box C/D snoRNAs.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
            <location evidence="1 10">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the eukaryotic ribosomal protein eL8 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697361">
        <property type="protein sequence ID" value="EFQ32370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096390.1">
        <property type="nucleotide sequence ID" value="XM_008098199.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QND2"/>
    <dbReference type="STRING" id="645133.E3QND2"/>
    <dbReference type="GeneID" id="24412879"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07514"/>
    <dbReference type="eggNOG" id="KOG3387">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084513_4_1_1"/>
    <dbReference type="OrthoDB" id="1924699at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031428">
        <property type="term" value="C:box C/D methylation guide snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031429">
        <property type="term" value="C:box H/ACA snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034511">
        <property type="term" value="F:U3 snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030621">
        <property type="term" value="F:U4 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000494">
        <property type="term" value="P:box C/D sno(s)RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000452">
        <property type="term" value="P:snoRNA guided rRNA 2'-O-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031120">
        <property type="term" value="P:snRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.30:FF:000002">
        <property type="entry name" value="NHP2-like protein 1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050257">
        <property type="entry name" value="eL8/uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002415">
        <property type="entry name" value="H/ACA_rnp_Nhp2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004037">
        <property type="entry name" value="Ribosomal_eL8-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018492">
        <property type="entry name" value="Ribosomal_eL8/Nhp2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23105">
        <property type="entry name" value="RIBOSOMAL PROTEIN L7AE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00881">
        <property type="entry name" value="L7ARS6FAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00883">
        <property type="entry name" value="NUCLEARHMG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01082">
        <property type="entry name" value="RIBOSOMAL_L7AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="12" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="11">
        <location>
            <begin position="18"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ32370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="125" mass="13504" checksum="8DE3C5ACD158CCE9" modified="2011-01-11" version="1">MADQSAAWPLADDALQQEILDLVQQCQHYRQLKKGANEATKTLNRGVSELIILAADTNPLSIVLHLPLLAEDKNVPYVYVKSKTALGRACGVSRAVIAASITSNEGSELAGPIRALRDKVERLAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNN6</accession>
    <name>E3QNN6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_07793</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697362">
        <property type="protein sequence ID" value="EFQ32523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096543.1">
        <property type="nucleotide sequence ID" value="XM_008098352.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNN6"/>
    <dbReference type="STRING" id="645133.E3QNN6"/>
    <dbReference type="GeneID" id="24413158"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07793"/>
    <dbReference type="eggNOG" id="ENOG502ST92">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029473_1_1_1"/>
    <dbReference type="OrthoDB" id="4812369at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ32523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="515" mass="57591" checksum="2E75E5F4E6FAD659" modified="2011-01-11" version="1">MREVEIFPQTFEIINHDSLFSINVTSEGLSSLKDDLTKGQRASVQKIDYQVILPEVVPKRFKKIQSKSEVSNNNEVFTKATRDFFNILTTWPSGDGAGIKLTISAASPSDVTIQDMMESGELESDRQFPVYETRWRTHALSIDRKLLAGGKLPDVACVSEFSFEAIHGRPFSPDAVSVVTSALVSVRKMLWEFLPPQVRVTYDRRLAWQSDLKAFRNALGVALTDTPFPKLVEFEIVTDSGDPSNELFQPPDMTGDGEDALSVGVRRLLQLETLEKLHLGSRWILTSAAFDAPLNCPRLKDLHIDLCVTTVDGKWLYTGDFDNLPVNEEYYGSEEDTEPEFDSEDSDASDFYPAVRTREAEGDIPELAFRVTPDNPVFVPLISTIAKAVPGMPELRRMRVMLGGSVRGTIAPLDIRYLAPGELETDESIENFSKENLERPRWCLMGYRDFDKSWRVPQELEKAFAGESGEGRFLLWTNPYGGAEEATSGPATQGDEGLDVLREGGKRVSNPHCVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNT4</accession>
    <name>E3QNT4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7730 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07711</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697362">
        <property type="protein sequence ID" value="EFQ32441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096461.1">
        <property type="nucleotide sequence ID" value="XM_008098270.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNT4"/>
    <dbReference type="GeneID" id="24413076"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07711"/>
    <dbReference type="eggNOG" id="ENOG502SR19">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062455_0_0_1"/>
    <dbReference type="OrthoDB" id="5420711at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056632">
        <property type="entry name" value="DUF7730"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24864">
        <property type="entry name" value="DUF7730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7730" evidence="1">
        <location>
            <begin position="3"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="266" mass="30216" checksum="86ADDCC3C4F9577D" modified="2011-01-11" version="1">MDKDKSPLMRIPAEIRMMIYEHLLDDGGEGRLAVRNKAMHQLPTGSILKTYRRSRYRIVERSFHRQCFETTYHLASKTRMHPAVMAVNRQMHRETSHMLYGLHGFDFGSDVEAVVPFLQDLTPQSRAMIREITVRKEGPLYNCESDRQDWANMCKYLRGLDKMVPKVRIVVEGGEPAAAWEGPQQLGVSDLRLLALIKHDSMEWIAELQRVEGIQQLEIIPHMRRLRPPGTTSTILFAAFSASIGTALVEFLRTDCGLPAAVASSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNU4</accession>
    <name>E3QNU4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_07546</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697363">
        <property type="protein sequence ID" value="EFQ32532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096552.1">
        <property type="nucleotide sequence ID" value="XM_008098361.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNU4"/>
    <dbReference type="STRING" id="645133.E3QNU4"/>
    <dbReference type="GeneID" id="24412911"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07546"/>
    <dbReference type="eggNOG" id="ENOG502SHPK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_787571_0_0_1"/>
    <dbReference type="OrthoDB" id="10261408at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053187">
        <property type="entry name" value="Notoamide_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47256:SF1">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47256">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="38"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="14"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ32532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="352" mass="39577" checksum="07BD841F48B74628" modified="2011-01-11" version="1">MPKRLAPLLPAEIGSDRFPLDTRREDPSKRKRVGTDVACNPCRRRKTRCDGKRPICAACRKRSTECTFVEKKESPRLGQSSGGSHEVLELLKSAPEQQAFEILRLLRTNGDPDSVLNIIKRGQHGIKRLPNNDTACAIRSMQSPLEFELMARNPATLRQALLTTLERDELLGARKLRRSNVPLHANDGFRVDVPPEGILDESRQSDPLLCDESFEDLRINCWTDTLMFHDYAARAIRFYPTTDNPFLSVFDPCLFISGLVGQCRAQSSLLLVNALMYWAYQMHTAINKRAVQFSENIISRGGEAVAPEWDNATNGHKHVLFGIAPSQARKGIEWVQTQTQLADSYTASGIFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QP14</accession>
    <name>E3QP14_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PCI domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_07616</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit p55 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697363">
        <property type="protein sequence ID" value="EFQ32602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096622.1">
        <property type="nucleotide sequence ID" value="XM_008098431.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QP14"/>
    <dbReference type="STRING" id="645133.E3QP14"/>
    <dbReference type="GeneID" id="24412981"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07616"/>
    <dbReference type="eggNOG" id="KOG1498">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033860_2_0_1"/>
    <dbReference type="OrthoDB" id="268763at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008180">
        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008541">
        <property type="term" value="C:proteasome regulatory particle, lid subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034515">
        <property type="term" value="C:proteasome storage granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000338">
        <property type="term" value="P:protein deneddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000070">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054559">
        <property type="entry name" value="PSMD12-CSN4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040134">
        <property type="entry name" value="PSMD12/CSN4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040896">
        <property type="entry name" value="RPN5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10855:SF1">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10855">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22241">
        <property type="entry name" value="PSMD12-CSN4_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18098">
        <property type="entry name" value="RPN5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="4">
        <location>
            <begin position="264"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="207"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="211"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ32602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="492" mass="56509" checksum="16F620C52BAF5E24" modified="2011-01-11" version="1">MSDGALKPEKDFSKETDKQIPEAEKLAESDISAAIEKLSVLEKQTRQSSDLASTSRILIAIVNIAKNAGDWSLMNEQVLILSKKHGQLKQAITKMVQAVMSFLDSTPNLETKLSVIETLRTVTEGKIFVEVERARITKTLSDIKKEQGDLKAATDILCELQVETFGSMDRREKTEFILAQVALCIEVGDWTQASILSRKISTRYLSRKPKKTPEQLEKEKKEREKKKARGEEVPEEKEDDTTDLKLRYYEQQIILAKHDDKYLDVCKHYRQVLDTEAVEEDPKKLHPVLQRIIYFVILAPHDNEQHDLLHRIQKDSRISQVSQEADLLKLFTVHELMRWPEVSKTFGPHLCETDVFDAQPGQSDDEKAHQRWLDLRKRVIEHNVRVVAKYYTRIQTQRLTQLLDLTEDETEKYISELVTSKTIYAKIDRPARIVSFAKPRDADDILNEWSSNMKSLLGHLERIDHLITKEEMMASIQPGASKSGKGKATKAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QP30</accession>
    <name>E3QP30_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Carboxypeptidase</fullName>
            <ecNumber evidence="6">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_07632</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase S10 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="6"/>
    <dbReference type="EMBL" id="GG697363">
        <property type="protein sequence ID" value="EFQ32618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096638.1">
        <property type="nucleotide sequence ID" value="XM_008098447.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QP30"/>
    <dbReference type="STRING" id="645133.E3QP30"/>
    <dbReference type="GeneID" id="24412997"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07632"/>
    <dbReference type="eggNOG" id="KOG1282">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008523_10_4_1"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033124">
        <property type="entry name" value="Ser_caboxypep_his_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF432">
        <property type="entry name" value="Y, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00560">
        <property type="entry name" value="CARBOXYPEPT_SER_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 7" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005127927" description="Carboxypeptidase" evidence="6">
        <location>
            <begin position="24"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ32618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="514" mass="56473" checksum="96017F2AC94BEE09" modified="2011-01-11" version="1">MVRLTSLAVSGLALFTGIASAVATQRDVESPEFTTFSVPEHPHHAIRIKEQSDEICDAGSRQWTGWLDTGGKHLFFWYFESLNDPEKDPLSLWMTGGPGGSGLVGLMLELGPCLINDNGTGTVHNPYAWNSNSSMIFVDQPAGTGLSYFDKGVTPPATSYTAAEDMNIFLRIFYKAFPHLATRPFHIVGESYGGHYIPTLAAEIVRYNTGSPAPDFKVPLASVMIGNGYVSPADTTWGFYDTLCTTKPGVPEPVFNASSCAKIAAALPRCMYLQEACYKYPDPIVCHAAGDFCFQNIDILYYQDVKPGGRNPYDITRPCETENICYGAGEGIETYMNSDRIRAALEIPAGVGRNFSLISWETNRAFDLAGDMSISTETEVKYMMESGVDVLIYNGDLDLACNTAGNVRWTNRLSWAGQVEFNAKEFEPWFAVKGGERVRGGKWKQVTKPTRGGKETRFTFVTIDGSGHMVPLDQPEVGLEMVRNWLYGDFGKATEGGVEVKLAGNEEHFVSLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QP32</accession>
    <name>E3QP32_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SCP-like extracellular protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_07634</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697363">
        <property type="protein sequence ID" value="EFQ32620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096640.1">
        <property type="nucleotide sequence ID" value="XM_008098449.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QP32"/>
    <dbReference type="STRING" id="645133.E3QP32"/>
    <dbReference type="GeneID" id="24412999"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07634"/>
    <dbReference type="eggNOG" id="KOG3017">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035730_5_0_1"/>
    <dbReference type="OrthoDB" id="337038at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018244">
        <property type="entry name" value="Allrgn_V5/Tpx1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00837">
        <property type="entry name" value="V5TPXLIKE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01009">
        <property type="entry name" value="CRISP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCP" evidence="2">
        <location>
            <begin position="134"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ32620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="302" mass="31614" checksum="F16325848F17432E" modified="2011-01-11" version="1">MRSSIVLAATGAVMAMGAALDRRVMETILDISYVTVTVTEGMEPTPTPTSSTPAVFYEAPVSVPKVEKSPEPAPAPVFQTIISNTPEPTPTPTPTPTPTPEPVVAPVAPSPPPAKPVVVETAPAAPSPAPVGDDLESTCINTHNLHRANHSAPALSWDSQLASYALVTAKTCVFEHDMSEGGGGYGQNLAMWGATGSESLGEAKAAQRAITEQWYNGEINLYPGYGLSSLDMSNFLSWGHFSQLVWVDSTTVGCAVNYCAAGTLSSIGSWYTVCNYKSQGNVIGKFAQNVLPPRNAASVYAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QP37</accession>
    <name>E3QP37_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Spermatogenesis-associated protein 20-like TRX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_07639</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697363">
        <property type="protein sequence ID" value="EFQ32625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096645.1">
        <property type="nucleotide sequence ID" value="XM_008098454.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QP37"/>
    <dbReference type="STRING" id="645133.E3QP37"/>
    <dbReference type="GeneID" id="24413004"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07639"/>
    <dbReference type="eggNOG" id="KOG2244">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014051_1_1_1"/>
    <dbReference type="OrthoDB" id="1923667at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02955">
        <property type="entry name" value="SSP411"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024705">
        <property type="entry name" value="Ssp411"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004879">
        <property type="entry name" value="Ssp411-like_TRX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42899">
        <property type="entry name" value="SPERMATOGENESIS-ASSOCIATED PROTEIN 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42899:SF1">
        <property type="entry name" value="SPERMATOGENESIS-ASSOCIATED PROTEIN 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03190">
        <property type="entry name" value="Thioredox_DsbH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006402">
        <property type="entry name" value="UCP006402_thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Spermatogenesis-associated protein 20-like TRX" evidence="2">
        <location>
            <begin position="37"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ32625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="811" mass="89024" checksum="135AE31B5CF7A130" modified="2011-01-11" version="1">MVASELSQAARAEKADPQSSQLIAQQAAPEPAPPLVNRVGQSKSPYVRGHAESRVAWQLLDEEAIERARKENKLIFLHIGFKACHYSRLTSTECFTHRECAAILNESFIPVIIDREERPELDTIYMNYVQAVSGSGGWPLNLFLTPELEPVFGGTYYPAPGPNNGGSDDEDRLDFLAILRKLQKVWREQEGRCRQEAKEVVVKLHDFAAEGTLGTATVQPGVAGSQTIAIGRSETGLEHPGTGRTAAAVSSELDLDLLEEAYSHIAGTFDPVYGGFGLAPKFPTPPKLSFLLRLPRYLAPVQDVVGESECAHATEMALFTLRKIRDSSLRDHVGGCGFARYSVTADWSVPRFEKLIAHNALLLGLYLDAWLIATGGEKGTEFYDVVVELVDYLSSPPISLPEGGFVSSEAADSYYRRGDRHMREGAYNLWTRREFDTVIGDDHEAALAASYWNVLEHGNVEPDQDPNDEFMNENILRVVKDVSEIGRQAGITVDEVKRVISSAKQKLKVHREKERVRPEVDAKIVAGRNGLVISALTRAGLALATVDAAKSQAAIASAGRAAEFIRANLWDEKERILYRIWNEGRGEAKGLAEDYAYLIEGLIGLYEATADERWIEFADELQKVQIDTFYDSPSVGTSVLESPASRSSCGAFYITAENAPHTILRLKDGMDTALPSTNAVSVSNLFRLGTMLSDEAYTALARESINAFEAEILQYPWLFPGLLSGVVTARLGGATWVVVRGSGGGEDELTQQLLRKLSLEASGGLRNVLLLKAEDDLLAKRSPALRELVQRPGTYRLENGVYRPITAADAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QP50</accession>
    <name>E3QP50_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_07652</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697363">
        <property type="protein sequence ID" value="EFQ32638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096658.1">
        <property type="nucleotide sequence ID" value="XM_008098467.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QP50"/>
    <dbReference type="STRING" id="645133.E3QP50"/>
    <dbReference type="GeneID" id="24413017"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07652"/>
    <dbReference type="eggNOG" id="ENOG502SNPN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_12_3_1"/>
    <dbReference type="OrthoDB" id="4682787at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF108">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="49"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ32638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="475" mass="53316" checksum="47725FCCA342476D" modified="2011-01-11" version="1">MSNAASPVGAFPPPPGVIPNFENPRDAGWLLNVIAMSVMVGATTIFFAIRAYVKSFQSGSLLLEDWTCAIAYLLIVLYIAVVFVMAHHGEGYHVWEITKEAYQNVMRWLYASSVIYIPAAYFTKVTLLLFEGRVFKVHERTSRGIRIFIIALFISYIPVQTLKTVVCWPISAFWDPRIPKSKCLNQRKIFIADMSLAILTDVVIIVIPMPLLWDLRLPLWKKVKILTLLGAGGIATAVTIYRMYLVVQFIYSKDVTADFVVLDILTALELVVGLICACLPSLNLLYERLRKRETKPTGNRPRSVREVKNKKENSQSTFALWSLMTGKQTRSARTEAPMTEGANSLQLKTNLDTEPGTLSSQEMGAIAQEEDLETDTVQCVGNDVFSPTAKSIDGRREEWPMAEAGSSSERVRIQRWKHHELEARNSWEAVWERAVPLGGLPPIPEDSGAPRLELTIHPQTDWESLDPANANHIMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QP79</accession>
    <name>E3QP79_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_07811</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697364">
        <property type="protein sequence ID" value="EFQ32667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096687.1">
        <property type="nucleotide sequence ID" value="XM_008098496.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QP79"/>
    <dbReference type="STRING" id="645133.E3QP79"/>
    <dbReference type="GeneID" id="24413176"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07811"/>
    <dbReference type="eggNOG" id="ENOG502RJJ8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_478961_0_0_1"/>
    <dbReference type="OrthoDB" id="5427664at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053018">
        <property type="entry name" value="Elsinochrome_Biosynth-Asso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37577">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37577:SF1">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="23"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="194"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="300"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="337"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="505"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="358"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="426"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="431"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="441"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ32667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="569" mass="65049" checksum="542B8276035A84A9" modified="2011-01-11" version="1">MGAACSSNADCNEFNEDPTDPDIMGIGVLLAFVVPVLLSTIAICLAYIARTTFHACLYMEIDNMILGRLERQRSVLASIRSTKYLQLILGLSDQLLVTSFGILIALYVQTCSMSLLCFRVGEALAYLASGVHMDCLLALGSHFEEHRRQAKVRIWLMAFLLVFILTTSFLTYLTDSNSVRRTVSCAIRHYKTDWPYLFVAWLALCWWVASSFRNSMSQLRNARSQFPRVYSLVNCALSAVYRDEASRRSLEAWNEYERQEMRAMYSRRCRQLRKRSPKPPWRVTARIVAQAIFGDFWRSLIFALCVNFSFTVTGIYFLLEVLVYARVDYSHLLEPKFGQILPLVMLIVLLLNIMEASGSPTETDGQSEARNDSPPRRRTERGQLTFLLPERNSRQGTDEWVVPPRRRVTVSEDRRQAGIEATMTGGLSRRQTGDTVREQSTHAYRQTTSIPEESEASGVELPNRVNTLVMEAGHLGEAESDGSFDTRFGLAAIVYQDTPRWIIKLAFFAALAATGVFFYFLCVYFNEMVIAMCALNQLYQLGHTCRGFWKFWRFRKERKEIQRRQPGST</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQF4</accession>
    <name>E3QQF4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08236</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697367">
        <property type="protein sequence ID" value="EFQ33092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097112.1">
        <property type="nucleotide sequence ID" value="XM_008098921.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQF4"/>
    <dbReference type="GeneID" id="24413601"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08236"/>
    <dbReference type="eggNOG" id="ENOG502RYWT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040838_0_0_1"/>
    <dbReference type="OrthoDB" id="5306317at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ33092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="256" mass="28475" checksum="E642A1CE173AC829" modified="2011-01-11" version="1">MATPIPPAYFELSWSILSTIGAANVLFGLLVIGITSFSQITMVPIVSSAAGSVANGLCFYAFYDHKYSLKNKATASAFGDVFWMIQEVGLSFYSYALLRKILKDRMWKVFNTLFWAAVLAIVAIRSMIALSRVRYILKGNTEIQDTVNSLHVSYFVLIASLECLSAFFLLKTFIQVKSTSDRAALKAGFFKYLMRSTEVRLATLAVLGTMRAVTYSFQMTAQSATNVASQLDRFAYALECLFPSVMLYAVSWFDPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQX6</accession>
    <name>E3QQX6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Negative regulator of the PHO system</fullName>
            <ecNumber evidence="2">2.7.11.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Serine/threonine-protein kinase PHO85</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">GLRG_08408</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">When phosphate concentrations are high it phosphorylates the PHO4 transcription factor thus establishing repression.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="12">Interacts with a number of cyclins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="2"/>
    <dbReference type="EMBL" id="GG697369">
        <property type="protein sequence ID" value="EFQ33264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097284.1">
        <property type="nucleotide sequence ID" value="XM_008099093.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQX6"/>
    <dbReference type="STRING" id="645133.E3QQX6"/>
    <dbReference type="GeneID" id="24413773"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08408"/>
    <dbReference type="eggNOG" id="KOG0594">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_181_1_1"/>
    <dbReference type="OrthoDB" id="1732493at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005935">
        <property type="term" value="C:cellular bud neck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990860">
        <property type="term" value="C:Pho85-Pho80 CDK-cyclin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000082">
        <property type="term" value="P:G1/S transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050849">
        <property type="term" value="P:negative regulation of calcium-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045719">
        <property type="term" value="P:negative regulation of glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016242">
        <property type="term" value="P:negative regulation of macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045936">
        <property type="term" value="P:negative regulation of phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016239">
        <property type="term" value="P:positive regulation of macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071073">
        <property type="term" value="P:positive regulation of phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031648">
        <property type="term" value="P:protein destabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901987">
        <property type="term" value="P:regulation of cell cycle phase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051302">
        <property type="term" value="P:regulation of cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032878">
        <property type="term" value="P:regulation of establishment or maintenance of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046822">
        <property type="term" value="P:regulation of nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032880">
        <property type="term" value="P:regulation of protein localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd07836">
        <property type="entry name" value="STKc_Pho85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000062">
        <property type="entry name" value="PHO system negative regulator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000410">
        <property type="entry name" value="Probable PHO85-cyclin-dependent protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF46">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 14 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 15" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="16">
        <location>
            <begin position="10"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00041795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00053974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00066118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00073154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EFQ33264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="321" mass="36890" checksum="A147EA143B2B1236" modified="2011-01-11" version="1">MDGKRHPSSFQQLEKLGEGTYATVFKGRNRQTGELVALKEIHLDSEEGTPSTAIREISLMKELKHENIVALHDVIHTENKLMLVFEYMDGDLKKYMDTHGDRGALKPHQIKSFMYQLLRGIDFCHQNRVLHRDLKPQNLLINGKGQLKLGDFGLARAFGIPVNTFSNEVVTLWYRAPDVLLGSRTYNTSIDIWSAGCIMAEMYTGRPLFPGTTNEDQIIRIFRIMGTPTERTWTGVTQFPEYKPTFQMYATQDLRQILPQIDPTGIDLLQRMLQLRPELRISAHEALKHPWFNDIVMQQHQQQALQAQARAYPGQGSYETY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQY5</accession>
    <name>E3QQY5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycine-rich cell wall structural protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08417</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697369">
        <property type="protein sequence ID" value="EFQ33273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097293.1">
        <property type="nucleotide sequence ID" value="XM_008099102.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQY5"/>
    <dbReference type="STRING" id="645133.E3QQY5"/>
    <dbReference type="GeneID" id="24413782"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08417"/>
    <dbReference type="eggNOG" id="ENOG502SCA5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056606_1_0_1"/>
    <dbReference type="OrthoDB" id="5388207at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ33273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="345" mass="35418" checksum="F9C2B0E2F41BBB37" modified="2011-01-11" version="1">METITTIANAANKAIWGTNEANQEPVSGVKGNTNQGEPYDAGNIEDPLIKEKKANIADANNASGTTGPAVTSEPSATTGVTTTSTPNTSTASTEPTGTSTTDDSSTHKSNPPTENTLPDRSRATEVITPNKSSTTGDSSKHQDIGKPELSKTSPSEVPPADSASGKTDTREPADPATDPAPKGQDVSNKSSGPIAGGDKLDGPGPKPLEIVAKERGGDAGNAKDSAKGGLVKGDSTSGIEDKNENDPREPSHGEGTGEKYVKSSGLAVDGGDFDATKPGAGREADRKCLLDEKDPAHAAAKADGKSSSDKTSDKTSEVRTHSPKSGTETEKESLKDKIKAKLHRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QR69</accession>
    <name>E3QR69_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FYVE zinc finger</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_08501</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697369">
        <property type="protein sequence ID" value="EFQ33357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097377.1">
        <property type="nucleotide sequence ID" value="XM_008099186.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QR69"/>
    <dbReference type="STRING" id="645133.E3QR69"/>
    <dbReference type="GeneID" id="24413866"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08501"/>
    <dbReference type="eggNOG" id="KOG1729">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082207_1_0_1"/>
    <dbReference type="OrthoDB" id="10018316at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15760">
        <property type="entry name" value="FYVE_scVPS27p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23164">
        <property type="entry name" value="EARLY ENDOSOME ANTIGEN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23164:SF30">
        <property type="entry name" value="EARLY ENDOSOME ANTIGEN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="6">
        <location>
            <begin position="169"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="17"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="229"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="79"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="229"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ33357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="284" mass="31772" checksum="5F5D520E1C91131E" modified="2011-01-11" version="1">MATDLIMPTLIEQRGPFFSQDRPHFSHVRSHSFQTVPQPQPFRNRTSPLSTPHDGSPTSPKSCLNESVRPVYVPAVLRPNKHHSKKPRATKVEDSDGGDLCLRRTNSSFISLPGFSVLGQKLSRRSTGDSGKIVDLELDADLFPQVTGEPTRKHWKPDTESVICDDPTCKRRFTPLNRRHHCRRCGNIFCHTHSNEVIPLDEDCNYNPRGTLARACFHCFTEFKVWKSRNGSRSGSDQSSDSSDTPSSPIVASPIVPMMPGMLPPTKGPEVAASVPRDWNWSTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRD4</accession>
    <name>E3QRD4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CUE domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_08701</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697370">
        <property type="protein sequence ID" value="EFQ33422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097442.1">
        <property type="nucleotide sequence ID" value="XM_008099251.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRD4"/>
    <dbReference type="STRING" id="645133.E3QRD4"/>
    <dbReference type="GeneID" id="24414066"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08701"/>
    <dbReference type="eggNOG" id="KOG0504">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040954_0_0_1"/>
    <dbReference type="OrthoDB" id="9942608at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031624">
        <property type="term" value="F:ubiquitin conjugating enzyme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14372">
        <property type="entry name" value="CUE_Cue5p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000064">
        <property type="entry name" value="Similar to CUE domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003892">
        <property type="entry name" value="CUE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041807">
        <property type="entry name" value="Cue5/Don1_CUE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16461">
        <property type="entry name" value="TOLL-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16461:SF5">
        <property type="entry name" value="TOLL-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02845">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00546">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51140">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CUE" evidence="2">
        <location>
            <begin position="87"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="398"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ33422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="449" mass="48650" checksum="937F4924ABC3C94D" modified="2011-01-11" version="1">MSAPNETSKTSAPESPTTVRPLDLSDDEDVQETGVLGAEAPNQNTTTNTTNTTNTTNTTNTTTSSTMASSTTAAEAPPPKPPRPSTETQKTEDILKEAFPSIDISVIKAVLRASGGKIDPAFNALLEMTDPDAAQNETADEQPPPQPPRPQGGGPQLSQLEADELYARQLAEHFDNFGSYEARTSNRSPGGRVQRQQTGLEPRPNAESRESNFFEDELPVIQEKLRKGFIETQGKVNSWITTMKKRFDEEFGEEDETGQRPGQAQGQYGARRPGESSRRSGDYERYDADPQVLSDDFAGMKFAADGTPLRDNSRPLSNPDLYKPPPPSKSPKPHDGRKVAFREGTEEIDVYGSSPRRSAEDLSGSKAKSSKWQPLSTVDPNPISDNDPFSLGDSEDEREAKEKAASSKDAKDVTSEDSERLKKAAAEAMADSLVESKGGEPADAAAKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRQ5</accession>
    <name>E3QRQ5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sir2 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_08822</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sirtuin family. Class I subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697371">
        <property type="protein sequence ID" value="EFQ33543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097563.1">
        <property type="nucleotide sequence ID" value="XM_008099372.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRQ5"/>
    <dbReference type="STRING" id="645133.E3QRQ5"/>
    <dbReference type="GeneID" id="24414187"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08822"/>
    <dbReference type="eggNOG" id="KOG2684">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023643_5_3_1"/>
    <dbReference type="OrthoDB" id="420264at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099115">
        <property type="term" value="C:chromosome, subtelomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031934">
        <property type="term" value="C:mating-type region heterochromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005721">
        <property type="term" value="C:pericentric heterochromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033553">
        <property type="term" value="C:rDNA heterochromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032041">
        <property type="term" value="F:histone H3K14 deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141222">
        <property type="term" value="F:histone H3K4 deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046969">
        <property type="term" value="F:histone H3K9 deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046970">
        <property type="term" value="F:histone H4K16 deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031508">
        <property type="term" value="P:pericentric heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030466">
        <property type="term" value="P:silent mating-type cassette heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902794">
        <property type="term" value="P:siRNA-independent facultative heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031509">
        <property type="term" value="P:subtelomeric heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF9">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="9">
        <location>
            <begin position="162"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="326"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="487"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="334"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="352"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="491"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="289"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="324"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ33543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="532" mass="59016" checksum="E5EF006F3C2F7194" modified="2011-01-11" version="1">MKTQRATTKTVTVKKRGKNNPKAVAAYKIDNLQAPESPTLEEIKHAVGLQELEERVKDAKESAWETDSLLEDAIAELGDAKLSLDDPDSCTPDEAMGLRHQLRALGPAEFCRRTVDAGRYTAKKLLSAFGLKPPAFLEGAEDEAYFSLLSLAISRELSKRAKLTRYNTVDDAVELLQRSKNIIVLTGAGISTSLGIPDFRSKGGLYSQLEHLGLNDPQEVFDISVFKQDPTIFYTVAKDILPSTNRFTPTHAFISMLEKQGKLLTNYTQNIDNLEAKAGISADKLIQCHGSFATATCVQCGFKCVGDDIFPDIKAGRIPRCPRCVQNLRPNGSTKRKRSAGTERKRRRFSSDDDSVSDGEYDMPSIGVMKPDITFFGEALPDEFSRRLTEYDRDKADLVIVIGTSLKVTPVSEIVSWLPANIPQIYISRQALNHINFDIDLLGDCDVVVSELCRRAGWPLKHEMVPEDQVVSVKPDGGCVSRHVFEAVNPQPQAQETQESGQQKQKQKQRGIKIEPGTVKPKNEPRKPRKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRX6</accession>
    <name>E3QRX6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">WD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_08543</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697372">
        <property type="protein sequence ID" value="EFQ33614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097634.1">
        <property type="nucleotide sequence ID" value="XM_008099443.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QRX6"/>
    <dbReference type="GeneID" id="24413908"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08543"/>
    <dbReference type="eggNOG" id="KOG0269">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002874_0_0_1"/>
    <dbReference type="OrthoDB" id="60955at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061700">
        <property type="term" value="C:GATOR2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016239">
        <property type="term" value="P:positive regulation of macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037590">
        <property type="entry name" value="WDR24"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46200">
        <property type="entry name" value="GATOR COMPLEX PROTEIN WDR24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46200:SF1">
        <property type="entry name" value="GATOR COMPLEX PROTEIN WDR24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 6" id="KW-0853">WD repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="254"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="439"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="719"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="765"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="896"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1212"/>
            <end position="1301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="736"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="770"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="798"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="814"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="851"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="896"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="1212"/>
            <end position="1236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ33614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1301" mass="140957" checksum="A9B63662FB54C9DD" modified="2011-01-11" version="1">MYNRENKIMRKLLGKVTADSSTDTHHSIAITSAPHFQASYRPSVPQNATFSAGVPILCLDSSPDRCAAVIAGRHVLKTIVFDGLSVNEAIDLRSAITAQSASSKTASSSLTADQLSIRDVKWHGDSTIFTACANGKIFSYDLARISIGGAALEFVQTREDSRQVNSLDINPHRQTTLLSGSQDGMVRYFDIRAPVQSRSGGLTYSPRGAYKCNADGVRQVKWSPKDGFYFACGTESGVILKWDVRKVAQPLLKIPAHDKACASISWHPDGNHLISGGWDSKCAVWDMSKNADKRQKPRWLIHTPAPVSAVAWRPGLWSASAQGKRAAQVAVSYDDGSHKRFGINSVHIWDLARPTMPYKEIDQFGFSPSGLLWQNQDLLWTAGNDGLFNQCDVAFAPKVLDRQPVSSMAFSARGDAVMFLDERPQDRPRPSIIHHQASVVPPRTSYSSSPTAPMLSISRSDSEEDVVGSFLGPRRRAGRKRRHSLRSVPVLSTTPPSGSGVSDDLVLGLEQAMKVTGTYKTQQSMAVGHIPAAARVDIYEYLSSCYLETMDRELPYVANGPPLSKRVCDIMEQYARAAEHVNQFRLAQTWRILAYSMNLLLSRRAQFHLETRLGQFQKRPSVAKAKDIPKIRVPRALDVVVEINGEETPRKPSAHISNSVDGKSLGPRSLLSEEIESTSNVTTPIARAINGENTNMGDFPSEAQLPPVMESDSFALPPAAHSTFNGSPRRRLDSVPLSTTSHESDGTQISITEGYDFYDTDTLSQAIDVPEPKNKEQKPLDYGPRTPNSRRTLRQDSDGSLAQMFSMSESSRQTSGLASSSEAGTSASTRSIVRYPTQLKEQRGVTDQVEYESRIRGKELEDSPEHGALTALHGPGASLPKDSPEEIFMISQTTMTSDTATDDPSTQSQSESLPAAYGDHAPLHIGVSSSTPPKITPALQHDSTPTILDSDYFPWPEDPSYPHPVAKEPDADYSPPLNPYTLINRALDFETRTSALNASAMVLLLKPLVPESVIDPVRATSILRQHHSRLAGMKLFIQAALLRKLCVRGWPEGIPEWGENYTSIFGPAQQGVKGGFMCLNCRKPRELDPSLGEKALWKCERCRTTMAPCAVCGHRETTAAALSVADGIGGAQPADPIMSTWWYCPGCAHGGHATCLQDWHAPSDDGTYKLSDGCCPLDGCGHACLPGKWREEKSVTRSDELGRMAMEKVRVGGNGGVAGGGGGGGGGGAGAGGGKSGAPSPVMPPNVRGDSIEVPQSRAVESVRETLASGAPTSGILSSSPGSRSGERERRKSVKFVPTER</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2011-04-05" modified="2025-06-18" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRY8</accession>
    <name>GFA_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Putative glutathione-dependent formaldehyde-activating enzyme</fullName>
            <ecNumber evidence="1">4.4.1.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">S-(hydroxymethyl)glutathione synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ORF">GLRG_08555</name>
    </gene>
    <organism>
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-(hydroxymethyl)glutathione = glutathione + formaldehyde</text>
            <dbReference type="Rhea" id="RHEA:22488"/>
            <dbReference type="ChEBI" id="CHEBI:16842"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58758"/>
            <dbReference type="EC" id="4.4.1.22"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1 2">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">One-carbon metabolism; formaldehyde degradation; formate from formaldehyde (glutathione route): step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Gfa family.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.22" evidence="1"/>
    <dbReference type="EMBL" id="GG697372">
        <property type="protein sequence ID" value="EFQ33626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097646.1">
        <property type="nucleotide sequence ID" value="XM_008099455.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRY8"/>
    <dbReference type="SMR" id="E3QRY8"/>
    <dbReference type="STRING" id="645133.E3QRY8"/>
    <dbReference type="EnsemblFungi" id="EFQ33626">
        <property type="protein sequence ID" value="EFQ33626"/>
        <property type="gene ID" value="GLRG_08555"/>
    </dbReference>
    <dbReference type="GeneID" id="24413920"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08555"/>
    <dbReference type="eggNOG" id="ENOG502SKH9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090716_0_0_1"/>
    <dbReference type="OrthoDB" id="3446116at2759"/>
    <dbReference type="UniPathway" id="UPA00562">
        <property type="reaction ID" value="UER00621"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051907">
        <property type="term" value="F:S-(hydroxymethyl)glutathione synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046294">
        <property type="term" value="P:formaldehyde catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1590.10">
        <property type="entry name" value="glutathione-dependent formaldehyde- activating enzyme (gfa)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00723">
        <property type="entry name" value="Formald_GSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014185">
        <property type="entry name" value="Formald_GSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02820">
        <property type="entry name" value="formald_GSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003829">
        <property type="entry name" value="PRK05417.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337:SF40">
        <property type="entry name" value="CENP-V_GFA DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337">
        <property type="entry name" value="GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033318">
        <property type="entry name" value="Formald_GSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_0000406158" description="Putative glutathione-dependent formaldehyde-activating enzyme">
        <location>
            <begin position="1"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="CENP-V/GFA" evidence="2">
        <location>
            <begin position="20"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1 2">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1 2">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1 2">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1 2">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1 2">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1 2">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1 2">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>structural</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="191" mass="20901" checksum="F0BC9194866BA9B4" modified="2011-01-11" version="1">MAPTLHPLIDNGITKGDPNFSGGTLRCHCRSKPVEVLLGGNVAHNHACGCSKCWKPAGSLFSVVGVIPREQVKVTANEEKLHIIDDSAVILRNACKECGVHMYGRIEKPHPFKGLDFVHVELSDQKGWQEPQFAAFVSSIIEQGFNPKGTDGVRRKFKSVGLETYDTLSPTLVDLISTWTAQQNGRLPAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QS81</accession>
    <name>E3QS81_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">LPXTG-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_08964</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697373">
        <property type="protein sequence ID" value="EFQ33820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097840.1">
        <property type="nucleotide sequence ID" value="XM_008099649.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QS81"/>
    <dbReference type="STRING" id="645133.E3QS81"/>
    <dbReference type="GeneID" id="24414329"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08964"/>
    <dbReference type="eggNOG" id="ENOG502T66Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060770_0_0_1"/>
    <dbReference type="OrthoDB" id="4148662at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178776" description="LPXTG-domain-containing protein" evidence="3">
        <location>
            <begin position="21"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="262"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="220"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ33820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="351" mass="36974" checksum="599BDB56C4EB3D21" modified="2011-01-11" version="1">MIGFFLFAWLFFGLLSPVLANYDQCYYDAGLVGPQELLPCLPANETDNGFSWCCMAGQFCVNQACYDGKSGVTYQYGCNDPTYKDKTCPIKGGLDRAKSPWIGLVQCNNANEGELKFWASNHPDTCGGNCPTEPDQPQVTQSVWPFEIQPLPPINDCKDLGKRVLAMYAPSALGSTGGVPATYTPPPGKPSPTRPPLRSSYATTTSIPVTESALQIASSGSSISTSSATPSSTSSATSSTASVATNAPAAPGPSSPALGNGAIAGIAVSSTAVALSALFAIFILLRRRLARKRGSEIVADEVEDDWQAGPAELPDDFHAISPESNEHPKINELSDNADSYILLFTTSIDAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSI4</accession>
    <name>E3QSI4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Beta-xylanase</fullName>
            <ecNumber evidence="11">3.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">GLRG_08966</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-xylosidic linkages in xylans.</text>
            <dbReference type="EC" id="3.2.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Glycan degradation; xylan degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the glycosyl hydrolase 10 (cellulase F) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.8" evidence="11"/>
    <dbReference type="EMBL" id="GG697374">
        <property type="protein sequence ID" value="EFQ33822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097842.1">
        <property type="nucleotide sequence ID" value="XM_008099651.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSI4"/>
    <dbReference type="STRING" id="645133.E3QSI4"/>
    <dbReference type="GeneID" id="24414331"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08966"/>
    <dbReference type="eggNOG" id="ENOG502QR4K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020161_12_1_1"/>
    <dbReference type="OrthoDB" id="3055998at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031176">
        <property type="term" value="F:endo-1,4-beta-xylanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044846">
        <property type="entry name" value="GH10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001000">
        <property type="entry name" value="GH10_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31490:SF35">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31490">
        <property type="entry name" value="GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00331">
        <property type="entry name" value="Glyco_hydro_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00134">
        <property type="entry name" value="GLHYDRLASE10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00633">
        <property type="entry name" value="Glyco_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00562">
        <property type="entry name" value="CBM1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51760">
        <property type="entry name" value="GH10_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="8 11 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="7 13" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179937" description="Beta-xylanase" evidence="13">
        <location>
            <begin position="19"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="GH10" evidence="15">
        <location>
            <begin position="23"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="14">
        <location>
            <begin position="382"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="346"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="356"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EFQ33822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="418" mass="44219" checksum="DA902609C911CC20" modified="2011-01-11" version="1">MHAKALIAVFLGPGLVSAQLNTLAVRAGLKYFGTAVGEGQVNDATYRAVVNNKNEFGSLVPENGQKWQGTEPSRGSFSFSNADIVPNIAKANGQILRCHTLTWHSQLPNWVSSGQWTAATLTSVIETHISNVMKHYLGQCYAWDVVNEAADDDGSWRTSVFYNVLGTSFLPISFRAAKAADPNTKLQSLTSTRYYNDYNLEYNGAKTNRVYEAVTIVQNAGAPIDGVGFQGHLIVGSTPSRSALATVLRRFTALNLEVAYTELDIRHSSIPASSSAQATQGNDYVNVVGSCLDVDGCVGVTIWGFTDKYSWIPGTFPGTGDALLWDSNYNKKPAYTSVSSLLAAAATSGTPPPPATTTAPGPGITTTAPAPGPTTSAPGGGPQSPKYGQCGGQGWSGPFACVSGTTCTFVNTWYSQCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSN2</accession>
    <name>E3QSN2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Sugar porter family MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_09014</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697374">
        <property type="protein sequence ID" value="EFQ33870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097890.1">
        <property type="nucleotide sequence ID" value="XM_008099699.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSN2"/>
    <dbReference type="GeneID" id="24414379"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09014"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_11_5_1"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000023">
        <property type="term" value="P:maltose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000149">
        <property type="entry name" value="MFS transporter, SP family, general alpha glucoside:H+ symporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF5">
        <property type="entry name" value="ALPHA-GLUCOSIDES PERMEASE MPH2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0462">Maltose metabolism</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="143"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="167"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="240"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="324"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="362"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="386"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="414"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="460"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="489"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="11">
        <location>
            <begin position="66"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="547"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00026248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ33870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="567" mass="62698" checksum="AE625AEF2E8E9A3B" modified="2011-01-11" version="1">MVLFGSSTPKAAPAMAVTTDPVVTRNLSGGDSSAAEVASEAAKATEAELGMGLMQSIRLYPKAIFWSLFFSTAVVMEGFDKTLIGNLFAYDVFQRKFGERQPNGSYELTAAWQAGLSNGALVGEITGLFLNGLIADRFGYRKTMVGGLIAVTAFIFIIFFSETLVQLLVGEILIGIPWGIFQTLTVTYASEVCPTHLRAYLTTYVNLCWVMGQLIASGVLRAMIQRTDEWGFKIPFALQWMWPVPLIIGILVAPESPWWLVRKERLEEAKASLLRLTSRNAQPDFNADETVSMMVHTNALEKAAQSGMKYTDCFRGIDLRRTEIVCCVWAIQTLCGSTFMGYSTYFYQQAGMDKANSFSMSLGQYAIGAIGTVFSWFLMQHFGRRTLYLTGQAIMCVVLATIGLVSFAGRENVAAQWAIGSLLLVYTFFYDCTVGPVCYSLVSELSSTRLRTKTVVLARNLYNITGITTNILTPLMLNPSAWNWGAKSGLFWAVSCAICFVWTWFRLPEPRGRTYGELEVLFEQGIPARKFSKTEVAGLTHRTHQNDRLSEKGSEVGVSEIEKTASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTR3</accession>
    <name>E3QTR3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Nucleoside diphosphate kinase</fullName>
            <ecNumber evidence="3 11">2.7.4.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_09369</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:44640"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the NDK family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.6" evidence="3 11"/>
    <dbReference type="EMBL" id="GG697378">
        <property type="protein sequence ID" value="EFQ34225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098245.1">
        <property type="nucleotide sequence ID" value="XM_008100054.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTR3"/>
    <dbReference type="STRING" id="645133.E3QTR3"/>
    <dbReference type="GeneID" id="24414734"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09369"/>
    <dbReference type="eggNOG" id="KOG0888">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060216_6_3_1"/>
    <dbReference type="OrthoDB" id="2162449at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006241">
        <property type="term" value="P:CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006183">
        <property type="term" value="P:GTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006228">
        <property type="term" value="P:UTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="NDPk_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.141:FF:000002">
        <property type="entry name" value="Nucleoside diphosphate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.141">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00451">
        <property type="entry name" value="NDP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034907">
        <property type="entry name" value="NDK-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001564">
        <property type="entry name" value="Nucleoside_diP_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023005">
        <property type="entry name" value="Nucleoside_diP_kinase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001908">
        <property type="entry name" value="PRK00668.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11349">
        <property type="entry name" value="NUCLEOSIDE DIPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00334">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01243">
        <property type="entry name" value="NUCDPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00562">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="Nucleoside diphosphate kinase, NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00469">
        <property type="entry name" value="NDPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51374">
        <property type="entry name" value="NDPK_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 11 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleoside diphosphate kinase-like" evidence="12">
        <location>
            <begin position="3"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="active site" description="Pros-phosphohistidine intermediate" evidence="9">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ34225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="153" mass="16790" checksum="24B1F49736250A2F" modified="2011-01-11" version="1">MASEQTFIAIKPDGVQRGLIGPIISRFESRGFKLVAIKLMTPGKAHLEAHYADLKDKPFFGGLIEYMNSGPICAMVWEGRDAVKTGRTILGATNPLASAPGTIRGDYAIDVGRNVCHGSDSVENAKKEIALWFKDGDVVQYKSAQFDWIYEKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QU00</accession>
    <name>E3QU00_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09482</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697379">
        <property type="protein sequence ID" value="EFQ34338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098358.1">
        <property type="nucleotide sequence ID" value="XM_008100167.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QU00"/>
    <dbReference type="STRING" id="645133.E3QU00"/>
    <dbReference type="GeneID" id="24414847"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09482"/>
    <dbReference type="eggNOG" id="ENOG502QS59">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025989_0_0_1"/>
    <dbReference type="OrthoDB" id="1708389at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021709">
        <property type="entry name" value="DUF3292"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38694">
        <property type="entry name" value="CONSERVED EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38694:SF1">
        <property type="entry name" value="PEROXIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11696">
        <property type="entry name" value="DUF3292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="641" mass="70915" checksum="18E5F6902DAD2499" modified="2011-01-11" version="1">MSCDQSQTQSHTLASSHIVHTNTEKLSEDRSVYDLGWNEKLDHDAEPWIRGTHNEDIWVLVRRLNKSLYEVRSAGEIPYGGLDLTVAEGLENTPNKLRSEMERLYMGLVLGLFSFAKTIARLRSWREPRRTGAFCIAYFIAWLLDYLNLLFVVAVIALILSPRARTILFPPAPLAMVDIRDGSIAKPMGGTLGSTDAATGAPQNLKGESVENEASNFITSVSAIATNLLTGKDPHGAPNEFDGSSEQGFKPQFDVTTMAVVKDKAEGMDRPSQDKTKAPMEEKVWEQMTPLLHMIILISDFWERLSNILVPTPPFDQRHHQRRLAAYILPLAAASIFLSRDTVIRCTSLAFGVAIFGDPLLTWCYHYSNTHRWTESIHINNTLFKGVPTNNQLALTLLRVGEANRAPIPPPEHMRHAPPDKPIDIDDDVISASMGDKPLGASQGQLENVAERDAEMADHAGGKDTEVQQVVGHGSKREKMFGLLKGGAKEVAKATSTVDKIRAKAGSKNAKTRVGALPSSKDEEQTIGPVEFSARYEGAKGFVYVNAAAGFVMFNKNSITEDNPNTVWTINIDSITQLRKHSGYGMKAKLASGWAVDGQIYDSLRIVDREGNHFVVTALPYRDALFNRLCAIGKHTKWEVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUA5</accession>
    <name>E3QUA5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_09587</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697380">
        <property type="protein sequence ID" value="EFQ34443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098463.1">
        <property type="nucleotide sequence ID" value="XM_008100272.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUA5"/>
    <dbReference type="STRING" id="645133.E3QUA5"/>
    <dbReference type="GeneID" id="24414952"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09587"/>
    <dbReference type="eggNOG" id="ENOG502SIUZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_482351_0_0_1"/>
    <dbReference type="OrthoDB" id="4524805at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180959" evidence="3">
        <location>
            <begin position="39"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ34443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="546" mass="58899" checksum="96117B0A780C32C7" modified="2011-01-11" version="1">MKPSQAFINLRPRLRLRFLSVTFFLALFIFCSPTTARAAPSVHETRNNNPLNINRDLTPSSPEDGPPAASAGALRDPSYLPYQIGAIVGSYGVSLVLVAALLLILSKRRREALAAGDEEVDFEEPKPHPPKLTLEVPNSPRSIPRSPVRNFSYPGADEYQTPEYPTPQTPYINPTPTSTLHAPGVDFAVDQTVVAKDRKMAQTQLEEMYKYVMEQEEAKAAGIKLEGSPVLPNSQSQLPTPTNAGFSKSTLRKEKHKPGNLTLGEEKGEKKQSRASSIFAALRSPKKQKEVRGISISSPIMTPMTGTFPRQESQELSAIPPRQYAPPPPPPAVPGSTSAYGGAQQHHGQMSPVSPEHSPESTQSIDERIGGQIPSGHARNHSAALSEMEHHSAVSERSTAPLIGLPQSPKPGARFSHTLPASPKPGSSFQIPPAPSAAGGFRSKAPSAVRTGGNLPLRAYEPAMSSPSLVPQTTKQTVFTRAGPLSPSGARTPATGMAVPYSPYQPFTPCVPMTPTLVTKADRKRMKKLEPKTPTLEMVRSENDIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QW69</accession>
    <name>E3QW69_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl hydrolase family 71</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_10247</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697388">
        <property type="protein sequence ID" value="EFQ35103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099123.1">
        <property type="nucleotide sequence ID" value="XM_008100932.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QW69"/>
    <dbReference type="STRING" id="645133.E3QW69"/>
    <dbReference type="GeneID" id="24415612"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10247"/>
    <dbReference type="eggNOG" id="ENOG502RZ85">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019141_1_0_1"/>
    <dbReference type="OrthoDB" id="1046782at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051118">
        <property type="term" value="F:glucan endo-1,3-alpha-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11577">
        <property type="entry name" value="GH71"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005197">
        <property type="entry name" value="Glyco_hydro_71"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051130">
        <property type="entry name" value="Mito_struct-func_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173">
        <property type="entry name" value="ABC1 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173:SF33">
        <property type="entry name" value="ASCUS WALL ENDO-1,3-ALPHA-GLUCANASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03659">
        <property type="entry name" value="Glyco_hydro_71"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178937" evidence="2">
        <location>
            <begin position="20"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="439"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="456"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ35103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="490" mass="53591" checksum="5CCBF1AF1AEA5213" modified="2011-01-11" version="1">MKFITICAGLLAAVTQVQASVVAHFMLINTMNYTLGDFEDDFRLAKEAHIDAFALNMGLTDPHTADALVDAFTAAKTVGFQLFFSFDYNGGYVGGKPWPKETILAMGEEYFRRDEYHKYAEKPVVSTFEGTENAEDWIEIKEKTSAFFIPDWSSIAPDKALELAGGVADGLFSWDAWPVGNQDMTSKGDAAYEWALKGKPYMMPVSPWFYTNLPGYHKNWVWRGDDLWFDRWTQVMEIMPTFVQIISWNDYGESHHIGPLRSNAMEAFEVGKAPFNYALDHPHDGWRHTLPFLIDSYKAAVQPAIRNESLTTWYRSSPALACKDGGTTASTAAHSQNILTAAEVVRDKIFYSALLTSAAEVTISVGGRSQKGIWTSTPEGGKGMYHGSAPFLGTGDVVVSMTKYGIEMAKIEGKPISNECPGGMTNWNAWVGARDALHVEDPNPATPTQTGDGPKSTASGDDGSSASSLSRGSLVYIIAVLACLTVAGVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWK9</accession>
    <name>E3QWK9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Arp2/3 complex 34 kDa subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_10391</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the Arp2/3 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasm</location>
            <location evidence="1 6">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ARPC2 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697390">
        <property type="protein sequence ID" value="EFQ35247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099267.1">
        <property type="nucleotide sequence ID" value="XM_008101076.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWK9"/>
    <dbReference type="STRING" id="645133.E3QWK9"/>
    <dbReference type="GeneID" id="24415756"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10391"/>
    <dbReference type="eggNOG" id="KOG2826">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059439_1_0_1"/>
    <dbReference type="OrthoDB" id="148331at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044396">
        <property type="term" value="P:actin cortical patch organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030041">
        <property type="term" value="P:actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072697">
        <property type="term" value="P:protein localization to cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006898">
        <property type="term" value="P:receptor-mediated endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1460.20:FF:000003">
        <property type="entry name" value="Arp2/3 complex 34 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1460.20:FF:000005">
        <property type="entry name" value="Arp2/3 complex 34 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1460.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007188">
        <property type="entry name" value="ARPC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034666">
        <property type="entry name" value="ARPC2/4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12058:SF0">
        <property type="entry name" value="ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12058">
        <property type="entry name" value="ARP2/3 COMPLEX 34 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04045">
        <property type="entry name" value="P34-Arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69645">
        <property type="entry name" value="Arp2/3 complex subunits"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="298"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="298"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ35247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="319" mass="36855" checksum="405C023A39D501F8" modified="2011-01-11" version="1">MLLLDYQNVLIQSVLTERFSGAPAAHIDQTISDFDGVIYHISTPETKTKIQLSIQIRCYKDLVKYGAEQVLQREYGQYVVPPEPGYDFSVMIDLENLPEDKDEREALIMKMALLKRNAMAAPFEAAYEEHYKLKEEASKYTSEEAPQGVREGGEVMAIHYREEEAIYVKASHDRVTVIFSTIFREETDRVFGKIFIQEFVDARRRAIQNAPQVLFRNDPPLELQGVPGVRDTGTGEIGYVTFVLFPRHLTPQRMPDVISHIQTFRDYFHYHIKASKAYIHSRMRKRTADFLQVLRRARPDSEEKERKTASGRTFKVQGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWQ3</accession>
    <name>E3QWQ3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RhoGAP domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_10435</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697390">
        <property type="protein sequence ID" value="EFQ35291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099311.1">
        <property type="nucleotide sequence ID" value="XM_008101120.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QWQ3"/>
    <dbReference type="GeneID" id="24415800"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10435"/>
    <dbReference type="eggNOG" id="KOG4269">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002671_0_0_1"/>
    <dbReference type="OrthoDB" id="185175at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13277">
        <property type="entry name" value="PH_Bem3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000452">
        <property type="entry name" value="Rho GTPase activator (Bem3)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050729">
        <property type="entry name" value="Rho-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176:SF129">
        <property type="entry name" value="RHO GTPASE ACTIVATING PROTEIN AT 16F, ISOFORM E-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176">
        <property type="entry name" value="RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="660"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="4">
        <location>
            <begin position="955"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="116"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="709"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="783"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="918"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1148"/>
            <end position="1270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="21"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="184"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="205"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="253"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="286"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="309"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="336"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="359"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="420"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="441"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="713"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="786"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1177"/>
            <end position="1192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1245"/>
            <end position="1256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ35291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1302" mass="142072" checksum="5FFD67ED92A0D75A" modified="2011-01-11" version="1">MSTSGGSAAAVRAKPSKGAPRNSSMDSAISAISTKSQSQKGATGSQSDPTDIAALIKTAGSPEAVIQYLLKEKQSQSQQNAQLWRLVDKQRAMILGLNKDLERALKDKEKYRKKLKEVMSTSEHTGPGESKTASKVLKMPMGKGIPAIDVSAPKERPVTAPDSPTLDSDSQKHSPVDMAMAPYPITPPADQPNGPPSAVGALLDPSHEMPKAHEHAYDRFNHDAEERAADMARRELEAEDLADIPINLGLPPSRSPPSQPPSMPPPKPPLASEAVTKSDEGLSQFPVPPPRKPPPAPLQLQDQTQPGRDDEDSESDFDDLLEVNEVLTERRGRRRTREEDDHDREILALKEAERRSLSKKSQTGTSTHANLDAPTELPPSPVKQMQGKNVPASLGEALSVSNLEAPLLSPGLPSSPRPPGLMSTDSPAASISSFPAASLSPRPPRQPIPLPPGHSLQTSAEATEPKVPQPLVLVKQGWDSASDKSRGSPTERGRIFKGFVTEEYPDLLLPPNVLPTIIVKVASSRMKPSRASLMSLTQLEEDPVFTLAVFSRSEPGELWRVEKDSASLAKLDQRLKQCLAFTAKTPERSLFNGHAPAKLDARRIALDHYLEELLDTPLDTASALELCRYLSTHTLPPNPDDAGSMESMVEAKANSGPGGRPFRTGYLTKRGKNFGGWKARFFVLDGPHLKYYETPGGAHLGTIKLPSAQIGKQSQSNENQSPQPSANSDDTDNQYRHAFLILEPKKKDSSSHVKHVLCAENDKERDQWVDALLRWIDYKDPEEDESHAAKQHAQDRPGTGTAERAEKKKQQRYKKTASQHQPSDSDLIGVRYDATSQGDLPHHGGPGRPRQAGHMPESHHPSETMAMSNQPPMISAPRDPQVIADTAQWGNKAGGGLAVPASEEKKIKKRSFFGFGAKARSSSDGQDSLFGGSELGSSTPPQGGYQGPIRQAFGAPLAEAVRFNPPVDVNVPLPAVVYRCIQYLDAKNAILEEGIFRLSGSNIVIKQLRERFNTEGDVNLVTDETYYDIHAVASLLKLYLRELPTTILTRDLHLEFMAVTEMSGQKEKVVALSELVQRLPQANATLLKYLIAFLIKIINNADMNKMTVRNVGIVFSPTLNIPAPVFAMLLQNYFGIFGLEPEEYELPSSFAEADSGRERSGSLPSMNNGLPNRPLYDTSQHGRPSTSAGSSHSPHRQRLLDSRPGQQRTSATPPPLLQDLQSARSSPTPPPNYPTSRPMAYEPQYMSQSYQSNGYHGSSRGYDGGPAAYDQPKRRESAIFMGNVVGLNPQSSKSRLREETQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWX3</accession>
    <name>E3QWX3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">UVI-1 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10505</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697392">
        <property type="protein sequence ID" value="EFQ35361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099381.1">
        <property type="nucleotide sequence ID" value="XM_008101190.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWX3"/>
    <dbReference type="STRING" id="645133.E3QWX3"/>
    <dbReference type="GeneID" id="24415870"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10505"/>
    <dbReference type="eggNOG" id="ENOG502T4TJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070105_0_0_1"/>
    <dbReference type="OrthoDB" id="4851554at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003181033" description="UVI-1 protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="232" mass="23699" checksum="59D4712615F24C99" modified="2011-01-11" version="1">MQSKIFNAAVAALSLPAVQCAVAPRQISITPGLIVLPGITIDPNTLGPQLSVFQTLDLVREDVGKTINLVNQITNTTAGTLLGTVSVATTVVGQVTNNVGTILDKVTQLTNLITPTLPAPTTPAPPNLPDIGGTAETLVRTVQELTRAVTAQLDALRNQAVGLAAATLLPLVATLQVTLQTALNLVGVASGLALSLAASAVSNVQTVVDRVLNAKAKLTGVLVIGIQPDISF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWZ3</accession>
    <name>E3QWZ3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zinc-binding dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10525</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697392">
        <property type="protein sequence ID" value="EFQ35381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099401.1">
        <property type="nucleotide sequence ID" value="XM_008101210.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWZ3"/>
    <dbReference type="STRING" id="645133.E3QWZ3"/>
    <dbReference type="GeneID" id="24415890"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10525"/>
    <dbReference type="eggNOG" id="KOG1198">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_4_1"/>
    <dbReference type="OrthoDB" id="9930022at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08276">
        <property type="entry name" value="MDR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052711">
        <property type="entry name" value="Zinc_ADH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45033">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45033:SF2">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C1773.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="19"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="353" mass="37378" checksum="8B6E162B697D5389" modified="2011-01-11" version="1">MASSMPSTIKQWNVVGQEGFQSLRFSEQTLPEFGDSQVLVRLQGATLNFRDIVIPHGKYPWDVKSNVVPGSDGAGTVLAVGKDVTRFKPGDKVITVLSPVYLGGPVTDGITKYGLGGSIDGTFRTVGAFSEQGLVSMPEALTFVEAASLTCAGVTAWNALFGLAGKRVSPGQWVLTQGTGGVSTFAIQFAKAAGARVISTTSSAEKAKILVELGVDHIINYRETADWGLEAKRLTGGSGVDLVVEIAGATTLGQSLASVKLDGTIVTTGYAGGEAKGQNMPTFLDSWLSLVTVRGVWAGSRLQMEEMCKAVDAQPDKLRPVIDSKVFKLEQIKDAYEYLESGKHQGKVGIEIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QX01</accession>
    <name>E3QX01_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">2-nitropropane dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_10533</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697392">
        <property type="protein sequence ID" value="EFQ35389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099409.1">
        <property type="nucleotide sequence ID" value="XM_008101218.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QX01"/>
    <dbReference type="STRING" id="645133.E3QX01"/>
    <dbReference type="GeneID" id="24415898"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10533"/>
    <dbReference type="eggNOG" id="ENOG502QTWN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038732_2_0_1"/>
    <dbReference type="OrthoDB" id="10265891at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018580">
        <property type="term" value="F:nitronate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04730">
        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332:SF31">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G09850)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ35389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="356" mass="37186" checksum="A61AA8EFBCC23225" modified="2011-01-11" version="1">MSLSTDLTRLLGMKHPIISAGMYIAGGPELVAAVSNAGGLGVIGGLYFTPDELRSTIQEVKNRLKDPSLPFGLNLLLPQVGGSARKTNWDYTKGKLDELIDIVVGSGAKLFVSAVGVAPKDVVDKLHANGIFYMNLVGHPKHVVKACAAGADIICAQGSEAGGHTGEIPTSILLPACADLVKKYVSPLTGQPVQLVAAGGICDGRGLAASFMYGASAVWMGTRFVTATESSALKESKQAVIEAGFDSTIRSTIWTGRPLRAAATDYIRKWEHERRDELQGLLSKGIVPIDHEADAFREAGGLPEDIAKQSAMRPMGMASGLINNGGQSAAEIVDEMVAEAVKCLSGAGCLVLKSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QX91</accession>
    <name>E3QX91_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Methyltransferase OMS1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_10623</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697393">
        <property type="protein sequence ID" value="EFQ35479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099499.1">
        <property type="nucleotide sequence ID" value="XM_008101308.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QX91"/>
    <dbReference type="STRING" id="645133.E3QX91"/>
    <dbReference type="GeneID" id="24415988"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10623"/>
    <dbReference type="eggNOG" id="KOG4300">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037990_3_0_1"/>
    <dbReference type="OrthoDB" id="416496at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050508">
        <property type="entry name" value="Methyltransf_Superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42912">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42912:SF83">
        <property type="entry name" value="METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ35479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="308" mass="33828" checksum="4A8900C3180B2E23" modified="2011-01-11" version="1">MSLLASSLYSSPCCQCPEPTLDAIPTGRPSVFTKESARKFDQSLDGSEWLMGVTALRQKMATEASGHVLEVAIGTGRNMPFYDWSNILQSQSTFPPSMGAEATVANSEGKRLDSSSAPILSYTGVDISSEMLGVAIEKLVETIPQLVGVTPRVMKQALPPHSDWGVFSYLSDRLRIFRSDIHDFVPPPPGQMSTLAKYDFVCSTFSLCSVRDPEQMVRDLANMVKPGTGRIILVEHGRGWSGFVNGLLDRSAASHFKKYGCWWNRDIAKIVESASKSLPGLEVVKVERPYFTQLGTTLWVELRVSPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXC8</accession>
    <name>E3QXC8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10660</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697394">
        <property type="protein sequence ID" value="EFQ35516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099536.1">
        <property type="nucleotide sequence ID" value="XM_008101345.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXC8"/>
    <dbReference type="STRING" id="645133.E3QXC8"/>
    <dbReference type="GeneID" id="24416025"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10660"/>
    <dbReference type="eggNOG" id="ENOG502RZFD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021587_0_1_1"/>
    <dbReference type="OrthoDB" id="5404323at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="365"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="431"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="436"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="558" mass="61755" checksum="718FE6ABCF6D2C73" modified="2011-01-11" version="1">MFLHSGASLHGHEYSNKPANNGPQPARRRSLLRSSLGASPLPRTSFSVDDAETTTQRINRRLSYQGPASPSRPSFRRNRPVSDLSPRKDLVVRFEEEPTVVREETNVLDGVSEDECSLVSGVSDTSTVVGSKRSRRAARQTTNYLLAYPPPKLRTKQRRFVQIRPRLLLQLQQLSNDKRPMPAIDVLPSSMIAGTVILPRLARRFPKMFRVKGQLGMNGLILTRSEDYDTPADDSDSDEKDLDTRDLVAVISPVERREGERRDSSDQTEIVLADGSVWTATQTSNGSYDFVHVDEAGRTTTARWARRNARPLSTATCAAVSKPAPASEYKFTFSILDPELRRHPVMATLTPANLEILDNYTTVSQSSARYPPTRPLSTDLCGDDEPSSPPSPALSMTKRETHPVDEATRTLITASSVWVSLRHGQGWASVPPPAASANQRPMHSRSVSSNSLCRTRASTFPVTSTEMGYITSPPLAQQQVMAQLAPVMPKRTYSSGAAFMQRRQSKLGSESVTADQAMETCDMGGLEKVMEPVPMKRSLTRRIRDWGHRLTVRKTATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXP1</accession>
    <name>E3QXP1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tat pathway signal sequence</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_10788</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ustYa family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697397">
        <property type="protein sequence ID" value="EFQ35644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099664.1">
        <property type="nucleotide sequence ID" value="XM_008101473.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXP1"/>
    <dbReference type="GeneID" id="24416153"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10788"/>
    <dbReference type="eggNOG" id="ENOG502SRWG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042941_2_2_1"/>
    <dbReference type="OrthoDB" id="3687641at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043386">
        <property type="term" value="P:mycotoxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365:SF7">
        <property type="entry name" value="TAT PATHWAY SIGNAL SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365">
        <property type="entry name" value="YALI0B05434P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="58"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ35644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="297" mass="33842" checksum="3D99E474C91B6158" modified="2011-01-11" version="1">MESQQRSDLDRSFSHGENLEKASMNLSSSGPDSDSSSFLGEKEIREIRSNHITRRRRWWWISFILIHAILLSVYIGSLLSLQAQVNKLRKYGPQLVNSPANDGVEWELQTFINNDNEHGPFSGPPREEVNRNWHRIINDENIILEPEYMKALGRDQFGVAVPDGSGFLGTLNVYHELHCIKRLYQYTYPDVYPQGDTPAEQASNRQHKDHCLDFLRQSAMCHADVGVITFQWSPKSLVPVANATHHQCANWDKLAQWTKGRTVDMMKPGWLIHPSKGEVAIHPTPPSLPLFAYSANS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXV5</accession>
    <name>E3QXV5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">D-isomer specific 2-hydroxyacid dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_10848</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697398">
        <property type="protein sequence ID" value="EFQ35693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099713.1">
        <property type="nucleotide sequence ID" value="XM_008101522.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXV5"/>
    <dbReference type="STRING" id="645133.E3QXV5"/>
    <dbReference type="GeneID" id="24416213"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10848"/>
    <dbReference type="eggNOG" id="KOG0069">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019796_1_2_1"/>
    <dbReference type="OrthoDB" id="9991913at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030267">
        <property type="term" value="F:glyoxylate reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016618">
        <property type="term" value="F:hydroxypyruvate reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12168">
        <property type="entry name" value="Mand_dh_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000282">
        <property type="entry name" value="Glyoxylate reductase protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050223">
        <property type="entry name" value="D-isomer_2-hydroxyacid_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10996">
        <property type="entry name" value="2-HYDROXYACID DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10996:SF269">
        <property type="entry name" value="HYPOTHETICAL D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase catalytic" evidence="5">
        <location>
            <begin position="59"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="6">
        <location>
            <begin position="120"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ35693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="338" mass="36419" checksum="43FACD741997CE43" modified="2011-01-11" version="1">MSRPKVLQLGEIEHAHEAWSGLSSVADIVKPKATSRAEFLDECRSGAFDGVKAIYRTFASVRTTGRIDAELLAALPESVGFICHNGAGYDQIDVPACTPRGILVSNTPTAVDDATADINIWLMLGALRNLNASVLSLRAGRWRGQPPPPLGRDPQGKVLGILGMGGIGRNFARKAAAFGMRVRYFNRTRLDPALEAECSASYVDFETLLRESDVISLNLPLNSHTRHTISHAQFAQMKPGVVIVNTARGAVIDEAALVDALASGRVASAGLDVFENEPEVHPGLLDNPNVLLVPHMGTWTVETSVKMEEWAIGNARRAVEEGRLNSVVVEQRDLAKTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QY23</accession>
    <name>E3QY23_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Probable transporter MCH1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_10916</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697399">
        <property type="protein sequence ID" value="EFQ35761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099781.1">
        <property type="nucleotide sequence ID" value="XM_008101590.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QY23"/>
    <dbReference type="STRING" id="645133.E3QY23"/>
    <dbReference type="GeneID" id="24416281"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10916"/>
    <dbReference type="eggNOG" id="ENOG502S0C9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012596_2_0_1"/>
    <dbReference type="OrthoDB" id="199930at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17354">
        <property type="entry name" value="MFS_Mch1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21576:SF45">
        <property type="entry name" value="TRANSPORTER MCH1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21576">
        <property type="entry name" value="UNCHARACTERIZED NODULIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="175"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="210"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="248"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="447"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="476"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="511"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="561"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00039330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ35761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="592" mass="63629" checksum="BAC51B59D1DE139D" modified="2011-01-11" version="1">MARASSPPTLSSDRTGVATPHDDDDASSTISRFSSRSSLDSERPLRRTRQSRRAANTLRAISFVAALVSALCAGSITVFSMYGHIFQERLHYTQFQVNGLAISSSIALYLPVSLLGYICDRVGTPPLSLLAAILFSGGYAVAAGTYRKLEAENLGGLRDYAGKRIAGGADWTYPLMIFAFVCVGVGTCSMYLAAVATCAKNFGKGKHRGLALAVPIAAFGLSGMWLSQLGSHVFYERLPDGSVGDLDVFRFFIFLSILLLVVGVIGTFTLKVVDEEDIIEEAAEELERSGLLERSTSFLSARDLERSRTYGSISRVADQEGSGLLGPAEDDAKLMKKMVLNAETRSFLTDKTMWCFAFGFLLMIGPGEAFINNLGTVIGTLYPPTMRYAGHPTSPATHVSIVGIASTVARLATGTLTDLLAPSPQTQHLQVSSTPPFLRGRPAVSRVAFLLFFALLLSLGLVALASGFIQEHGERFWIVSGLIGTGYGAVFSLTPIIITVIWGVENFATNWGIVAMFPALGSTFWGLVYSAVYQSGAENSPQREGAGDAFCYGKQCYAPTFWAMAITVWVACGMILFAWKGKGGWAQRGIVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QY93</accession>
    <name>E3QY93_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GTPase binding protein Rid1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_10940</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697401">
        <property type="protein sequence ID" value="EFQ35831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099851.1">
        <property type="nucleotide sequence ID" value="XM_008101660.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QY93"/>
    <dbReference type="STRING" id="645133.E3QY93"/>
    <dbReference type="GeneID" id="24416305"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10940"/>
    <dbReference type="eggNOG" id="ENOG502RXE8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008022_0_0_1"/>
    <dbReference type="OrthoDB" id="2155261at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030036">
        <property type="term" value="P:actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010473">
        <property type="entry name" value="GTPase-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06371">
        <property type="entry name" value="Drf_GBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01140">
        <property type="entry name" value="Drf_GBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Formin GTPase-binding" evidence="2">
        <location>
            <begin position="300"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="351"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="767"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="416"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="784"/>
            <end position="793"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ35831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="827" mass="91737" checksum="18C2894667133CF6" modified="2011-01-11" version="1">MGSAAAGDNNGGGRPRSSVLKSFIHRRNQSEGSALFTSPPSVQVTTTPAQHIHTTYARLEGRMPPPPIRTEGLGALGELNNNFQKDPVPRSPRKDDDRDRSRSPTKSTFGNMSFKSFAKDARKSRDVPPEKPKKTKSSTNLTGFLSRPRSAMSLNKNPKEEEEEEEERRSAKDKENRTPPSSTSSADMTGPAPPIYAQFCSQDLGSNGLRGKTSFDVGSGRYGSDASSEVKKQRPKSYHPSTAVSEAKSTSDLRSGMTTDGRVPSASERIKSKVQRPKLFTAFSAMGHSTKSKGSDASSDKAIDPNEIDAHLEAMLDRRNIPENQRYKMRNLADTIKMEFIRQDWAEMAAKEQAGTAESNESAPAVTGGSDREETQSKRSRGRSFTLSRKKDPASPTKKPKGDGSTIGRHFRSKSSDSVVSDRPVSASSTASNGILSKIKFGQGPGDYVSYLRKVQKPELVEVGKLHKLRLLLRNETVSWTEDFIRQGGMEEIVGLLNRILEIEWREEHDDALLHENLLCLKALCTTALALQYLHSIHDDLFPKLLHMLFDPEKKGPSEFTTRNIITSVLFTYIETASPAERVARAQKVLSFLRNPQPKEEEKPVGFVLEMRKERPYTVWNKEVVSVTKEVFWIFLHHLNVIALPSEMSTKGGAPLSAITNGAQEPYGFMSRHFPSERPPVPAAPYVGGVEWDATNYLASHLDLMNAIIACTPTTAQRNNLRNDLRISGWEKVLGGSLRLCKEKFYGCVHEALRCWVAAATEDGWDARDVRYGPPPESRNTSPAKKTNAAQKAKAPEVAPKIEMPKLDFGLDNHRVTPVRERDAWLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZ59</accession>
    <name>E3QZ59_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11291</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697411">
        <property type="protein sequence ID" value="EFQ36147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100167.1">
        <property type="nucleotide sequence ID" value="XM_008101976.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZ59"/>
    <dbReference type="STRING" id="645133.E3QZ59"/>
    <dbReference type="GeneID" id="24416656"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11291"/>
    <dbReference type="eggNOG" id="ENOG502SN0Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002639_3_1_1"/>
    <dbReference type="OrthoDB" id="4814906at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF16">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="57"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="549" mass="61260" checksum="C9FF99F38153F141" modified="2011-01-11" version="1">MNQMVKFIRSCVDTCDSEHALCKQPTLRMPARVLDVGRMDDNQVQLVDTASMMVSPYVALSYCWGESNHLLTTEKNFQDMTTGIYVAEFPQTIRDAVEVTRRLNLKYLWVDAICIIQDSALDWEVESAKMASVYHNAYLTIAAGTSACASEGFLDQQHLSASHETPFRMKWRTDRGETSILAVRAVPARHTHSINLAGDRQNSLPLNTRGWSLQEELLSRRTITYTQNELWWTCQTQRDCECHAFDEITRDGPKALMSPTLMTTHSAAFEQWQAVVSEFSTRKLSYELDKLPALSGLASVVQKKTGSSYVAGLWKDNFVRDLNWYSPARTLDKLEDAKAKATGAYCAPTFSWASANGLIGFFKGSFAVSQTGVVPTTEWVARCTLIAANTVVGGSNPLGRVESGYATLRGHLSEALLGVSTACPSGMESHTLRYHGEWVRFHPDMQLEEVQLTAAGSKGAPAVSMRRSPAGSRAQTLRSESPVLLFYLGDWGFPDQEIIRIQRTYLVLGRSPLDTSQYERLGLAHHEPRFELNKTAQGCEGWVETITLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZ78</accession>
    <name>E3QZ78_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_11330</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697412">
        <property type="protein sequence ID" value="EFQ36166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100186.1">
        <property type="nucleotide sequence ID" value="XM_008101995.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZ78"/>
    <dbReference type="STRING" id="645133.E3QZ78"/>
    <dbReference type="GeneID" id="24416694"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11330"/>
    <dbReference type="eggNOG" id="KOG1721">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075838_0_0_1"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379:SF127">
        <property type="entry name" value="BLOODY FINGERS-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379">
        <property type="entry name" value="KRAB AND ZINC FINGER DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12874">
        <property type="entry name" value="zf-met"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="32"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="93"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="196"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ36166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="275" mass="31402" checksum="7A8E6C51A6765812" modified="2011-01-11" version="1">MAFACGTCWRTWSTRTARDQHVAAKSHQVPNYECESCDRYFNSQRSVEQHMDALGHWADSASDEPQHYCDFDACSEVFDNEEDLRQHEVEEHFYCDPCDRGFQDLNSINMHRNGKQHRGKNASCRFCNASCVTAAGVFQRLEQGAYPKAPLDRMKVYEAVQRSDPNSVLTKRLLEWSTSTSFEATSESWNADTETFDCFLCGSGFARLDSLNQHLQSPKHQQKLYHCPKQSCRKEFGTLAAVCNHLESGSCNLMSFEAVQETAKRIFDPGRMIAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZR4</accession>
    <name>E3QZR4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chromo domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_11497</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <dbReference type="EMBL" id="GG697420">
        <property type="protein sequence ID" value="EFQ36352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100372.1">
        <property type="nucleotide sequence ID" value="XM_008102181.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZR4"/>
    <dbReference type="GeneID" id="24416861"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11497"/>
    <dbReference type="eggNOG" id="ENOG502T5EA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099916_0_0_1"/>
    <dbReference type="OrthoDB" id="433924at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="2">
        <location>
            <begin position="86"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ36352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="153" mass="18263" checksum="46D297EF21515D7D" modified="2011-01-11" version="1">MVISGHARLNDGETVLKLTLGNDKVDNDERAFLAWVPEHTLQAKDPEAVYQYWESLPGGRDYQLGYVHQWAANRRLGRHEQHNVKWEIFRVSKFRVRKRETELLVHWQGYREEESSWVLERDIDQQSPEAVTSFWKEHIKSAKVAPRKRTRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0C3</accession>
    <name>E3R0C3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">O-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_11706</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697438">
        <property type="protein sequence ID" value="EFQ36561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100581.1">
        <property type="nucleotide sequence ID" value="XM_008102390.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0C3"/>
    <dbReference type="STRING" id="645133.E3R0C3"/>
    <dbReference type="GeneID" id="24417070"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11706"/>
    <dbReference type="eggNOG" id="KOG3178">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005533_0_1_1"/>
    <dbReference type="OrthoDB" id="2410195at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="COMT-like"/>
    </dbReference>
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        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012967">
        <property type="entry name" value="COMT_dimerisation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712:SF2">
        <property type="entry name" value="O-METHYLTRANSFERASE CICE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08100">
        <property type="entry name" value="Dimerisation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase dimerisation" evidence="6">
        <location>
            <begin position="89"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="5">
        <location>
            <begin position="258"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="30"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="52"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ36561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="465" mass="50646" checksum="201F2209D7C8792B" modified="2011-01-11" version="1">MANTAEQHIAHLRSLLDTLTTSTNDLIVELSSSSSSSSPKSKIGNGATTNHGDIRVPKDPKTEDARKRVIAATASLEAAVLTPQWRLGHLAHSYFVSRALHMVVEWEIPKLLAANGPMGLDALATETGVVDTRKLGLVMRTLCAHHIFAETALNVFANDEASTALATDERLASSVRYASFLFPTADVLPNLLKDPALCASYASQDSAFARSIGKSLGQFEYLNAHPEWRDSFNLWLASLGEYLHGLTDVGGYPWESTLRNGAVVVDVGGGLGSSIQALRTNFPDRRGREDFVGIVQDQPGMIEHATAHWQRTDPQALATGAVKLTAHDFFHENPVKGADVYWFRSVIVDWQDDDLTKIFMHIRDAMAPGKSRLLIGEYIMHPTCGDALLPNAPSPLLKNYGEFQAMGLISGFILTVSPNGVQRTIHDVSKVVEAAGLKIVKVWICRGLGHVIECRLKEDVYSATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0L0</accession>
    <name>E3R0L0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11794</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697455">
        <property type="protein sequence ID" value="EFQ36648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100668.1">
        <property type="nucleotide sequence ID" value="XM_008102477.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0L0"/>
    <dbReference type="STRING" id="645133.E3R0L0"/>
    <dbReference type="GeneID" id="24417157"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11794"/>
    <dbReference type="eggNOG" id="KOG2806">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_703998_0_0_1"/>
    <dbReference type="OrthoDB" id="73875at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="392" mass="42143" checksum="49E59801BD379477" modified="2011-01-11" version="1">MSLLKLVLDVGASLIWDGCIPVPGGGRPGGAFSWWLGPCGGTELVPEEIKETFGILSSVTDGVSRFKKPKAPKGSGKKGDDANLTNRAKPKQGTGSGANVLGKTQLGSVGIRKKCNVPKSQSTQRLGIAKNTMRRQSCVADQTQREEVIVTSLTYSARTTQVKATCSAACSQACYYYSSVIRNNQAWATLTCPQAAATTAHRQDGQATATWSTQHRGSGWTEEINRQQEGCDCDEYPPAYLLDANSPAILNSGVDRTGQLVRYVPDTEKHKAGQMWKGACFGGTLQDLSDTNFDAAVSRDPASAKHVSRPKSQLLRTYMDSGVNTHPEFTIASYDHFGSPPANDGLNDNQCWPSGIAAADSGFALLTYDPYYDTNPMPYRYDQAYVQGANGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0P1</accession>
    <name>E3R0P1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11825</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697462">
        <property type="protein sequence ID" value="EFQ36679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100699.1">
        <property type="nucleotide sequence ID" value="XM_008102508.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0P1"/>
    <dbReference type="GeneID" id="24417188"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11825"/>
    <dbReference type="HOGENOM" id="CLU_2305888_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="100" mass="10722" checksum="061C1EC39BDDDD73" modified="2011-01-11" version="1">MPGNSETEDIRRDDGALLQQQQQQHSAIPDADAPVQPLESPVSLAMGAKRPESHSLSRTPDGDNILPLSGTESRSATPSSTGIVDFPDPFYKGHVEVEDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2H0</accession>
    <name>E3Q2H0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_00415</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089291.1">
        <property type="nucleotide sequence ID" value="XM_008091100.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2H0"/>
    <dbReference type="STRING" id="645133.E3Q2H0"/>
    <dbReference type="GeneID" id="24405780"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00415"/>
    <dbReference type="eggNOG" id="ENOG502R1FB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_219188_0_0_1"/>
    <dbReference type="OrthoDB" id="4774177at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ25271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="41" mass="4908" checksum="A5EDFBFAF2B3E87F" modified="2011-01-11" version="1">MPFFYSKPIGGRNFGTSVHADRHGVRRGPWRFRIGRFHCFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2W5</accession>
    <name>E3Q2W5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Calponin-homology (CH) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00088</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ24944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008088964.1">
        <property type="nucleotide sequence ID" value="XM_008090773.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2W5"/>
    <dbReference type="STRING" id="645133.E3Q2W5"/>
    <dbReference type="GeneID" id="24405453"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00088"/>
    <dbReference type="eggNOG" id="KOG2046">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024074_0_0_1"/>
    <dbReference type="OrthoDB" id="21595at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015629">
        <property type="term" value="C:actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21210">
        <property type="entry name" value="CH_SCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050606">
        <property type="entry name" value="Calponin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003096">
        <property type="entry name" value="SM22_calponin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47385">
        <property type="entry name" value="CALPONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47385:SF14">
        <property type="entry name" value="TRANSGELIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00307">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00888">
        <property type="entry name" value="SM22CALPONIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00033">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="2">
        <location>
            <begin position="21"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="374"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="459"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="512"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="525"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="561"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="592"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="607"/>
            <end position="621"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ24944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="643" mass="71467" checksum="E615F94D9D4CD387" modified="2011-01-11" version="1">MASVTSLDKDLRKLRLDKYTPAAAKEVSAWIEGVLGERLPSGDLLEGLKDGVALCKLINLAVPPPGVKFKKSAMPFVQMENISHFLRACKQPPLNLQDHDVFLTVDLFEQKDPAQVLQCLGAFSRAAHAANPSKFASPIGSKSRGVMSPQATGRGTPSPTRSRGFSNASGFGSPRPNLTSAKTGDSGSGRWSPTKPTSPVSSWSRKEHEGATSPAWNIAQYGYMGGASQGNLGISFGSRRQITSAGPSVPSLADKEKRRKEKEAEEERQRQQMAELRRQKEEELEREAHLREEQEIQRLVEEKQRQADEERRQWEEEERMWKLTEEKRRKEEAEAEARLAEERSRARSKSDARLRGQFLSQYQSEQAIKPQKTGADRIAELEKELEEARERERRYELERQGRTGRTLAATNDPKARLRSRSRPSDGAPSRQDSWSKSEREVLQTAWSQHQDAHDNEHPALPPRSPRPLPDPMTVAKPPQKAVAHTTGGRPLPDPAAYKAANQPPPSRTDRFLANNAAPAPLAAKQTYSRELSATAEQDAEDHRRAQSQNKTKAGGWASKSLLEREMEMERERQREWEEAQKETARAVPTGNGVDGIGGGIGGRWDVSQWSGYTGGDNQNKGAQGIGAGRRQIVGPRPLPNVPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3D4</accession>
    <name>E3Q3D4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7492 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_00680</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089556.1">
        <property type="nucleotide sequence ID" value="XM_008091365.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3D4"/>
    <dbReference type="GeneID" id="24406045"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00680"/>
    <dbReference type="eggNOG" id="ENOG502SABV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019095_1_1_1"/>
    <dbReference type="OrthoDB" id="64281at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055915">
        <property type="entry name" value="DUF7492"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24320">
        <property type="entry name" value="DUF7492"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180045" description="DUF7492 domain-containing protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7492" evidence="3">
        <location>
            <begin position="22"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="326"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ25536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="429" mass="45815" checksum="C9429F87E522F7A5" modified="2011-01-11" version="1">MVRRNLLAVAIATILGAPHVAESHTWVEQLNRVAANGTLVGPAGFSAGWTGRMSSAFNDATFTNRIPGDGFAMCKQPVGQQVEGFPALTAAPGDFVSLRYQENGHVTLPNTPENKPLNRGTVFIYGTTEPKADDTLFDVHRQWTADGKGGDGRGRLLATRNFDDGQCYQINDKSISQERQSKFPHEAAQPMGRDVWCQSAVQLPEDLAQNSDYTLYWVWSWPTLTPSAHAASKNGQFADFPAGFTKDKRAATSKDVTVAELYTSCSSIKVKGEKLVSGVKSASKSTSKSGKANGKLAGFNLLQKPDYNNNAVKDQLANQFQVRVDGQGAPISSNPSNGTQSSAPTATAAPAAPTGATGVTSKVRVVTVTVTAQPVTLYSMVTVTAYAQSTPAPAKKHAGNEGAAQADVTPFLKGRHIRHRDSWKFGQSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3E2</accession>
    <name>E3Q3E2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_00688</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_008091373.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="24406053"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00688"/>
    <dbReference type="HOGENOM" id="CLU_723631_0_0_1"/>
    <dbReference type="OrthoDB" id="4736382at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
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    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ25544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="382" mass="42070" checksum="9BA64A6645D1BC5B" modified="2011-01-11" version="1">MIRPSWGGPTELRLESQLQREKFPQYQSHVSAPDPTGTYWFDQYAPTAYKTPYGYQPVLHFYNKLLYPSTTQKRQLEDPGEMLPSSAARQMPPIDGFNDISSSPDTAPDFMEGPKAKRARLELKNNNFAQVPTAKPAQMSMDNLKHQGMEQGTTNFCDIAPSEEPAAPVDSDKADDTYADGNKNKHFPCSQFIKGVGHKTQPKDSPTMPSSFQIPQIWDNNACTNSTSAQGPTSVPTSLSTATQSTMVSTDTSSMFSDAAWSQIFNKMEFGPQNNHQASNSFHFPQLLEAHDPVMNQAVQDSLEAFVGDAIVETDTSGYVWDGENLGQSGSEVMAVPEQSGFNNGLDFLDGLDHFDDDIDWSFDPLLGDDLLPGAYLTHGVD</sequence>
</entry>
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        <recommendedName>
            <fullName evidence="4">DUF1479 domain-containing protein</fullName>
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    </protein>
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        <name evidence="2" type="ORF">GLRG_00696</name>
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    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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    <dbReference type="OrthoDB" id="8249012at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21521">
        <property type="entry name" value="AMUN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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            <end position="250"/>
        </location>
    </feature>
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        <location>
            <begin position="207"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="250" mass="27870" checksum="28F2BED3D3B7A102" modified="2011-01-11" version="1">MSCEEFRQLLANYDLLIDSISTSKGAKAGQKTLQELDQFRFVDAPALFSQDGPKRAMNHDDVKCLVDWKLRHGKFRPTLMKLVSSNDSSAVEDTVKKAIDNYRDMADLSAALNILTKMKGIGPATASLILAVHYPQKVLFFSDEAYYWLCNKGQKASLKYSMKDYEHLDSQASKLLKRLGVGAMEVEKVAYVLLKQEGSIPKPTPDSPSTSVKTTSKPKQSAPVKKRKSVEDSLEDKVPLRRSKRGKVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3Q8</accession>
    <name>E3Q3Q8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein kinase domain-containing protein</fullName>
        </recommendedName>
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    <gene>
        <name evidence="11" type="ORF">GLRG_00804</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
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    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
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            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="GeneID" id="24406169"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00804"/>
    <dbReference type="eggNOG" id="KOG0032">
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    <dbReference type="OrthoDB" id="1738954at2759"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="Aur-like"/>
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        <property type="entry name" value="Prot_kinase_dom"/>
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    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
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    </dbReference>
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        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
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    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="122"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="13"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="468"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="22"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
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    </feature>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
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            <end position="545"/>
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    <feature type="binding site" evidence="7">
        <location>
            <position position="153"/>
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        <ligand>
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            <end position="203"/>
        </location>
        <ligand>
            <name>ATP</name>
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            <begin position="251"/>
            <end position="252"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="298"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="cross-link" description="Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)" evidence="8">
        <location>
            <position position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ25660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="603" mass="67529" checksum="5C562D5F105C8CDD" modified="2011-01-11" version="1">MSTIQQLKNFIRHGKQARAANGETSPKQQNSPPQKAQVGITEPAIGAANPVQPAPEAYSLAGDDQQNRVAQAGHAAAHAVEPNQNKTSKAGKNIDSAHIAKLIAEENESKSKFPRYPGLERWELLEKMGDGAFSNVYRARDTTGEYPAQCAIKVVRKYEMNSMQRANILKEVQIMRQLDHPNIIKLIDFSESRQYYYIILELAPGGELFHQIVRLTYFSEDLSRHVIVQVANALEYLHEERGVVHRDIKPENILFSPIPIVPSKTPKPKQPGDEDKVDEGEFVPGVGAGGIGQIKIADFGLSKIVWDNQTMTPCGTVGYTAPEIVKDERYSKSVDMWALGCVLYTLLCGFPPFYDESIEVLTEKVAKGQYTFLSPWWDDISKSAQDLISHLLTVDPEKRYTITEFLAHPWIKGSGPTPREEKKSQPEMLRAFDATKLVDGDRRYDFRSPGAVNLREVFDVGYAVHRQEEEAKRRKQVGTKGGVPARFLNNLNEESEDEDQEMADSKEAEYVHKPSQATQALEKSMRNAQIRDQQEQQRGRERERQAPINEKGYGQHSAAITAAARQQVRDRNRQKGAFELSLDGATLLGRRNKQPLAAQAGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3X3</accession>
    <name>E3Q3X3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_00869</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089745.1">
        <property type="nucleotide sequence ID" value="XM_008091554.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3X3"/>
    <dbReference type="STRING" id="645133.E3Q3X3"/>
    <dbReference type="GeneID" id="24406234"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00869"/>
    <dbReference type="eggNOG" id="ENOG502RX7Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019313_1_0_1"/>
    <dbReference type="OrthoDB" id="5213892at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF20">
        <property type="entry name" value="PRO1A C6 ZINK-FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="36"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="95"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="175"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="189"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="199"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ25725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="701" mass="77315" checksum="CA3C82D968FC1CA3" modified="2011-01-11" version="1">MFSRNKDLSHMSSLSGLRSRFKHTMSSSAKIRSSEGCWTCRLRRKKCDEARPVCDGCAQLEITCYYSDVKPDWMDGGERQKEMADSLKKQVKIQANNRRERKYLQSLDVDPNHTPASDDPDHVIPPVPPLSLDGGSSKANDSNSPSTVNDTPGDTSSPAFHMGSVKSSLHDLAPAASPNQMRQLSPEWPSHSNHSSPPAAAPAPAPAPATLPASHPAVPISADHSNAPPFSDDSNLTFIMIYLDYVFPFLFPFYKPALLEGGRSWLLNVLNHNKALYHTALGLASHFFGVVLTGAQVEHAPCRMKSVASLQHQLDLALRELRADMASINEGGVDNQLRRGCRVLESIVQLLIFDVTIASNDHWQMHLDAATVVFQQILPQPDHWDATMDHMAIPLFSGVRFPPGSHTAWSSDQAALRFFTASLLYFDIISATALERPPTLQAYHYHLLSPRKDDCLELEPRLRLEEYFGCQSWVLQIIGEIAALDAWKKDARRAGSLSMTHLVSRAACLELALREGISCIDNQCPQLMGSDDLVAACSNACTGRPPPHPTHADTMRLPPDPLTLYQYSQTQDAVDAAHAHTKIWAYAALTYLSTVVSGWQPSCPETVTSVQATLDLLNTLRSPVCLRTVVWPFCVIGCLADPRQENMFRDMAARMGPLEVFGSLTGALGVMENVWARRDTIDESWDLAACFKILGHPVLLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3X6</accession>
    <name>E3Q3X6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ENTH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00872</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089748.1">
        <property type="nucleotide sequence ID" value="XM_008091557.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3X6"/>
    <dbReference type="STRING" id="645133.E3Q3X6"/>
    <dbReference type="GeneID" id="24406237"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00872"/>
    <dbReference type="eggNOG" id="KOG2056">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040577_0_1_1"/>
    <dbReference type="OrthoDB" id="4033880at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030125">
        <property type="term" value="C:clathrin vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030276">
        <property type="term" value="F:clathrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006895">
        <property type="term" value="P:Golgi to endosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16992">
        <property type="entry name" value="ENTH_Ent3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.90:FF:000006">
        <property type="entry name" value="Clathrin interactor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013809">
        <property type="entry name" value="ENTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12276:SF45">
        <property type="entry name" value="CLATHRIN INTERACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12276">
        <property type="entry name" value="EPSIN/ENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01417">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00273">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50942">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENTH" evidence="2">
        <location>
            <begin position="27"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="455"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="322"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="455"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="479"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ25728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="513" mass="53285" checksum="DD7FE29D23B2F2FF" modified="2011-01-11" version="1">MDWNNLKDTVASMTLYDVKAGVRKVQNAVMNYTEMEAKVREATNNEPWGASSSLMQEIASGTFNYATLNEIMPMIYRRFTEKSAEEWRQIYKALQLLEFLIKHGSERVIDDARGHITLLKMLRQFHYIDQNGKDQGINVRNRAKELSELLSDVERIRTERKKARATKNKYIGVEGGGGGGFSSGSSSRYGGFGSESGGYGGYSGGVYGDGGGFGGQEANDYGRTQAHNDKFEEYDEFDDERPAASSSASRSKRPERAAAAPKAEPPKKKEPEVDLFSFDDPAPSSMPAPVVAPTPSTGAGIVSLSAPSASNDDDEFDDFQSAAPAPAPAAATPLSPPVMTANSATTFAAPQPVSAPQQANIGNMVSMSSMSPAPSANYSAFSTTAVASPATQAKPTAYQPSGPNYFSSVPAAAPQAARGSLAATPGAAVPKAASAAAKPSAAGGDAFGALWSQASSGVKKTSTPTTGPALGQLAKEKSSAGIWGAPAPAASAPKPAGGSSSTGGNHGLDDLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4A3</accession>
    <name>E3Q4A3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_00559</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089435.1">
        <property type="nucleotide sequence ID" value="XM_008091244.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4A3"/>
    <dbReference type="STRING" id="645133.E3Q4A3"/>
    <dbReference type="GeneID" id="24405924"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00559"/>
    <dbReference type="eggNOG" id="ENOG502T4C0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087981_0_0_1"/>
    <dbReference type="OrthoDB" id="4837814at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ25415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="276" mass="31189" checksum="89354BD5FA4DA8B1" modified="2011-01-11" version="1">MCLRLYRHYTECGCLLAARASLRECRHGPTSPLCGPQHTIGIVTREGEECLYHACLTKQQQNAPEQSRKPCFRRPSGPGVTDKEVAEAKVEHLRSLDMRERLDRFKAKGLEGSYRGDREFRPRGGALVFSRQFDGTEYTGRHPYEHTDFEEEDVAQQKTRCHLRNVFLATVQREGLFDPSDRFLSSAWDDDSNSSACSSEVHPDALDTTSYSEGAKPMASWEEMNGGRDIVAGEDNAMDVDETDLCNVYREDSYSPVERTLKLKDLTGLRPNRASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4T0</accession>
    <name>E3Q4T0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein SSH4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Protein ssh4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">GLRG_01239</name>
    </gene>
    <organism evidence="20">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Components of the endosome-vacuole trafficking pathway that regulates nutrient transport. May be involved in processes which determine whether plasma membrane proteins are degraded or routed to the plasma membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endosome membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SSH4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ26095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090115.1">
        <property type="nucleotide sequence ID" value="XM_008091924.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4T0"/>
    <dbReference type="STRING" id="645133.E3Q4T0"/>
    <dbReference type="GeneID" id="24406604"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01239"/>
    <dbReference type="eggNOG" id="KOG1477">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016552_1_1_1"/>
    <dbReference type="OrthoDB" id="258495at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12910">
        <property type="entry name" value="SPRY_SSH4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.920:FF:000065">
        <property type="entry name" value="Ear1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001870">
        <property type="entry name" value="B30.2/SPRY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003877">
        <property type="entry name" value="SPRY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035780">
        <property type="entry name" value="SPRY_Ssh4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050618">
        <property type="entry name" value="Ubq-SigPath_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12864">
        <property type="entry name" value="RAN BINDING PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00622">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00449">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50188">
        <property type="entry name" value="B302_SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0967">Endosome</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="13 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="8 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <keyword evidence="7" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="B30.2/SPRY" evidence="18">
        <location>
            <begin position="80"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="313"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="326"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00025244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EFQ26095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="479" mass="52262" checksum="0545D00BA1709016" modified="2011-01-11" version="1">MAPTTPSSALNGVVIGLLSSFGSAVLIALVFLVIYFFRYTASGRIFLDRIGRPGEYDDEQAFAKEETEALESMDDMQRTEYLRAKAFIQANPPESLQTDISLSQYLAIQEKGVSAWEFEPELEIANCFVEGRTEIEFFDSECTVMSNLPVPKQNEVYYWEAKIYDKPENTLISIGMATKPYPLFRLPGFHKHSAAYLSAGQRRCNQPFAATPYGPQYVQGDVIGVGYRPRTGTIFFTRNGKKLEDVIHGVKSQNFFPAVGANGPCIVHVNFGQAGFVFIEANVKKWGLAPMTGSLAPPPPYGSEQGDILLEAGRKDGYTGGGHQRAPSQTQSYNQASLGPRHGRTRSGNFRVLPPRSPGPVRSPTDISLTHFVPDDEGGEPSSSSNRGHEGQSVVGLGLQDALNPPPEYTSPDNSEAGSRRNSTDSENTPLIRVLNRNRGASTTGGSGPSHPPIPSYTDAVEVAERTMIFELKLLGRTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q599</accession>
    <name>E3Q599_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Superoxide dismutase</fullName>
            <ecNumber evidence="13">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">GLRG_01010</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="function">
        <text evidence="2">Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>2 superoxide + 2 H(+) = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the iron/manganese superoxide dismutase family.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="13"/>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089886.1">
        <property type="nucleotide sequence ID" value="XM_008091695.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q599"/>
    <dbReference type="STRING" id="645133.E3Q599"/>
    <dbReference type="GeneID" id="24406375"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01010"/>
    <dbReference type="eggNOG" id="KOG0876">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031625_2_0_1"/>
    <dbReference type="OrthoDB" id="239262at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.990:FF:000001">
        <property type="entry name" value="Superoxide dismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.55.40.20:FF:000004">
        <property type="entry name" value="Superoxide dismutase [Fe]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.990">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.40.20">
        <property type="entry name" value="Iron/manganese superoxide dismutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050265">
        <property type="entry name" value="Fe/Mn_Superoxide_Dismutase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001189">
        <property type="entry name" value="Mn/Fe_SOD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019833">
        <property type="entry name" value="Mn/Fe_SOD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019832">
        <property type="entry name" value="Mn/Fe_SOD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019831">
        <property type="entry name" value="Mn/Fe_SOD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036324">
        <property type="entry name" value="Mn/Fe_SOD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036314">
        <property type="entry name" value="SOD_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11404:SF29">
        <property type="entry name" value="SUPEROXIDE DISMUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11404">
        <property type="entry name" value="SUPEROXIDE DISMUTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02777">
        <property type="entry name" value="Sod_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00081">
        <property type="entry name" value="Sod_Fe_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000349">
        <property type="entry name" value="SODismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01703">
        <property type="entry name" value="MNSODISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54719">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46609">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00088">
        <property type="entry name" value="SOD_MN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0464">Manganese</keyword>
    <keyword evidence="6 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Manganese/iron superoxide dismutase N-terminal" evidence="14">
        <location>
            <begin position="5"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Manganese/iron superoxide dismutase C-terminal" evidence="15">
        <location>
            <begin position="96"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000349-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EFQ25866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="208" mass="23026" checksum="C0B22E4AE66E225E" modified="2011-01-11" version="1">MASPQYILPKLPYAYDALEPHISAQIMELHHSKHHQAYVTNLNKAIETYNANPLQNRIAVLAALNFNGGGHINHSLFWENLSPASSGDASPDAAPKLVAEITRVWGGLDQFKQAFNTTLLGITGSGWGWLVKDDITGLSIITTKDQDPVTKGVPIFGIDMWEHAYYLQYLNGKAAYVENIWNVLNWKTAESRFSGSRDDAFTALKAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5Z1</accession>
    <name>E3Q5Z1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Large ribosomal subunit protein mL59 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_01383</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090259.1">
        <property type="nucleotide sequence ID" value="XM_008092068.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5Z1"/>
    <dbReference type="STRING" id="645133.E3Q5Z1"/>
    <dbReference type="GeneID" id="24406748"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01383"/>
    <dbReference type="eggNOG" id="ENOG502RZ2K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076154_1_0_1"/>
    <dbReference type="OrthoDB" id="18529at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037507">
        <property type="entry name" value="Ribosomal_mL59"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040922">
        <property type="entry name" value="Ribosomal_mL59_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28041">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN L25, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28041:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18126">
        <property type="entry name" value="Mitoc_mL59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Large ribosomal subunit protein mL59" evidence="1">
        <location>
            <begin position="16"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="160" mass="18401" checksum="04A82435E11BEB87" modified="2011-01-11" version="1">MAAAEQYIQLAKALPQQLQRFFARWPPASILPAGVTVPKTGFQEITPNPFSPQKHPATGKWHDPVYSLRRQAEIVKLARQHGVEELLPPTVKGTEYRIARRVEHGLRVKGTGVGQKVKGKIHERMVQPRMEKRREAMLAMPKLIKEWKKVGKRNWTRFPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6Q5</accession>
    <name>E3Q6Q5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GDSL-like Lipase/Acylhydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_01647</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090523.1">
        <property type="nucleotide sequence ID" value="XM_008092332.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6Q5"/>
    <dbReference type="STRING" id="645133.E3Q6Q5"/>
    <dbReference type="GeneID" id="24407012"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01647"/>
    <dbReference type="eggNOG" id="ENOG502S78G">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065222_1_0_1"/>
    <dbReference type="OrthoDB" id="408760at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004622">
        <property type="term" value="F:phosphatidylcholine lysophospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00229">
        <property type="entry name" value="SGNH_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051532">
        <property type="entry name" value="Ester_Hydrolysis_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383:SF19">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383">
        <property type="entry name" value="THIOESTERASE 1/PROTEASE 1/LYSOPHOSPHOLIPASE L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="246" mass="27842" checksum="8C2244508B667634" modified="2011-01-11" version="1">MSEGKTLRVFCFGDSLTAGYSAYGAVYHPYSIALTKKLSRDLSDTRVIATDNGMPGDLVSQGAFAKRFESETSQAAYDWVVVLGGTNDLAYSVPPERIFESLRQVYDSAIAKGSKVLALTVPECANQDDELDSRRRRLNNTILTHQSPNYHAFDLNPRIPYHSLTERERQRYWDDGLHLTVAGYDWMGTHVAEALGDLVELERNPNSRRARRARRHVEEEICFDEEDGDPRSLSGGYVFVRMRDLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q774</accession>
    <name>E3Q774_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_02532</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090732.1">
        <property type="nucleotide sequence ID" value="XM_008092541.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q774"/>
    <dbReference type="GeneID" id="24407897"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02532"/>
    <dbReference type="HOGENOM" id="CLU_2015084_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ26712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="123" mass="13738" checksum="9B138C8766597631" modified="2011-01-11" version="1">MHPDPGEKDPPRDSCRPYSNNSGLSEWFYESSSHGSNRSQTLETSRRRKFCICQMRLCSRVPAPDIVTQGLPARIWRDQGHPQLCLKAKTKGAHCTQSTHHATGTQFSHSIAVAHNQNGLKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q891</accession>
    <name>E3Q891_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_02274</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091123.1">
        <property type="nucleotide sequence ID" value="XM_008092932.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q891"/>
    <dbReference type="GeneID" id="24407639"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02274"/>
    <dbReference type="eggNOG" id="ENOG502RZM0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009027_1_0_1"/>
    <dbReference type="OrthoDB" id="5381672at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="121"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="558"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="687"/>
            <end position="737"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ27103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="756" mass="81694" checksum="B4B7C0111FBF62A3" modified="2011-01-11" version="1">MSQQPLRYARRPVYILAAYLFLLVVPWLCLCVVNRRTTSDPLGIVMQDDLDSYRRWLSAASFLGIVAAVAALPCVTALLAYGAVIFSQRRSKQQSLTVRQLLAISDLKWTAFVSSGESSSYLLLATGLLLLAAVQPPLQSLLMPASSRLVYPCDSSRHLSKWDRSCDGVENRAQKIGKDAEPVLLRETGAPPIVGAVRSKMVNITSADIQENLWRDGDTQRSFMTGEAQAYNESFWVSAVPAGATTGPLRQHSIRLSSSAKCEVAGRDAFPVSCDGYATSLEGFGVVVRTCMPGSHANTDSGIPPRRRQDVEETLFIDAQISGEAAKSKDFLPEPAENVTIKCVARTTRAFFEIGNLHTGSRPSDIVDEWPSDMAHFHDYDWLGNLITNTSQDDWNRDRFAGWTSPQGPLRSTVEALFGNGSYPEAVFDFLRQTFPDQQLPDNQAPDGAVRDATRKACALEAPFSSWQLPYNSDNDEFDSWFASAYQACSLKELPKTLFRIAQGLRYEKVAKSTLGVGMYLSNAAVLQDAAANDAARTIYNLTGIGFVAPRYTLGATVAISLLISAQAVALILLVFYIYSLPTWTDTLDAFAMMRLGAHLRESVELPSLGRVNRGEVAVLGETDGLLGVVPGTAGDSEEDVELAALAPSSATRRDGASAHHYAMLSPLSPTSTLSSREALVPPTHARQDATMPGMDAGELSDFLQGAPPATPSVSSTHSSPPPPPYMPARSPNRGQRARGPLRLALGASGPITGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8A6</accession>
    <name>E3Q8A6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Zinc carboxypeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">GLRG_02289</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Extracellular metalloprotease that contributes to pathogenicity.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the peptidase M14 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091138.1">
        <property type="nucleotide sequence ID" value="XM_008092947.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8A6"/>
    <dbReference type="STRING" id="645133.E3Q8A6"/>
    <dbReference type="GeneID" id="24407654"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02289"/>
    <dbReference type="eggNOG" id="KOG2650">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019326_1_1_1"/>
    <dbReference type="OrthoDB" id="3626597at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03860">
        <property type="entry name" value="M14_CP_A-B_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000165">
        <property type="entry name" value="Glucan 1,4-alpha-glucosidase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057247">
        <property type="entry name" value="CARBOXYPEPT_ZN_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705">
        <property type="entry name" value="PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705:SF143">
        <property type="entry name" value="SLL0236 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00765">
        <property type="entry name" value="CRBOXYPTASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00133">
        <property type="entry name" value="CARBOXYPEPT_ZN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52035">
        <property type="entry name" value="PEPTIDASE_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="17" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="8 15" id="KW-0732">Signal</keyword>
    <keyword evidence="11" id="KW-0843">Virulence</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="13" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180297" evidence="15">
        <location>
            <begin position="20"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M14" evidence="16">
        <location>
            <begin position="116"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="14">
        <location>
            <position position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS52035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EFQ27118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="431" mass="48066" checksum="EDC5FAD1C0E50769" modified="2011-01-11" version="1">MKLTAALLLLCPLVAGAAATPRDGKVSYDGYQVYRVSTANSPKDLSRLRLFPSAAQNGFIEVAIPPKEIDSFKSLDLEKQLLNEDLGKLIRAESSAQKPASLTKRGELPPLSWFDSYHAYDDHVQYWKNLQTAFPNNSEWLDIGSSYEGRNIFGLRLWGGNDTGTKPVVLWHSTVHAREWITTMTVEYLTYQLINGYKSGDKNVTAFFDAYDFYIVPFHNPDGFVYTQTTDRLWRKNRQKRSNVTCIGTDGNRNWDFQWDYPLEDGSVSADPCSETFHGLTPGDTPENIALSALSRKLAAKPGGVRLFIDWHSYSQLILLPWGFSCQSEVLPKNLQAQRDVGAGYAAAINATSGEQYQVGPSCEILYYSTGSARDFHHGALNATYSWSVELRPKSGGDGDGDSGFILAPEFIWPTVKEHWEGIKYVLSAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8L7</accession>
    <name>E3Q8L7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_02059</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ26888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090908.1">
        <property type="nucleotide sequence ID" value="XM_008092717.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8L7"/>
    <dbReference type="GeneID" id="24407424"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02059"/>
    <dbReference type="HOGENOM" id="CLU_2236397_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ26888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="105" mass="12366" checksum="EBC607B2D7832258" modified="2011-01-11" version="1">MPSGRLICGNHDHGAVIGIRKQLDTLSEEDVTQFEPDFDKATVQIHSLPVLVKWQILLQQAAAHLNLIRSTRIFKDFKPPIHHYRHPRLMLARSRRRSRTQRRWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8U2</accession>
    <name>E3Q8U2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Probable aspartate--tRNA ligase, cytoplasmic</fullName>
            <ecNumber evidence="3">6.1.1.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Aspartyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">GLRG_01951</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>tRNA(Asp) + L-aspartate + ATP = L-aspartyl-tRNA(Asp) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19649"/>
            <dbReference type="Rhea" id="RHEA-COMP:9660"/>
            <dbReference type="Rhea" id="RHEA-COMP:9678"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.12" evidence="3"/>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091476.1">
        <property type="nucleotide sequence ID" value="XM_008093285.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8U2"/>
    <dbReference type="STRING" id="645133.E3Q8U2"/>
    <dbReference type="GeneID" id="24407316"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01951"/>
    <dbReference type="eggNOG" id="KOG0556">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004553_0_2_1"/>
    <dbReference type="OrthoDB" id="372395at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017101">
        <property type="term" value="C:aminoacyl-tRNA synthetase multienzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004815">
        <property type="term" value="F:aspartate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006422">
        <property type="term" value="P:aspartyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04320">
        <property type="entry name" value="AspRS_cyto_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000038">
        <property type="entry name" value="Aspartate--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02075">
        <property type="entry name" value="Asp_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004523">
        <property type="entry name" value="Asp-tRNA_synthase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024320">
        <property type="entry name" value="LPG_synthase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00458">
        <property type="entry name" value="aspS_nondisc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003483">
        <property type="entry name" value="PRK05159.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43450:SF2">
        <property type="entry name" value="ASPARTATE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43450">
        <property type="entry name" value="ASPARTYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09924">
        <property type="entry name" value="LPG_synthase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="14">
        <location>
            <begin position="260"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="48"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="69"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00070516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EFQ27456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="889" mass="101367" checksum="FE107EDE43D9FC2D" modified="2011-01-11" version="1">MTQQEAVSRSPSTLSRLAQKFTSPLKSPPSSPTVSTRTRTTVFEKKSPISSSTSQSSKSSTGRSPVRSGEIRRQERGEKLQRRQEEERQLQERRRSEYEEGRRAEDEETRARYGEGDEGEYPTELTTIGEAVKLDIGTKVTFRARIHTQRNISKHLDFLLFRDQTDTVQGVLAHATPNMVKWVQHLHPESIVQVSGTLKKPVQDVKSAHYHDVEVDIYSIHLLNPAKAPPFSNYMPPDSMNFRLNNRILDLRHPSNQALFRVRAMITRQFRETLDNSGFIEIQTPKLQPAATESGAEVFKLNYFGRRAFLAQSPQLAKQMTISADFGKVYEIGPVFRAENSNTHRHLTEYTGLDIEMKIQKHYHEIIKVLDQTLKNIFAAVHSMPELKIIRERFPSDDLVWLDETPIISFRDGLQMLRDDGRDVEDEDLSTPDEIRLGELVKEKYGTDYYILDKFPANARPFYTHKADDPFWTNSFDIFVRGQEICTGGQRINDPKELRKNMAEKGISEDDMAEYLEAFDLGAPPHGGAGLGLDRVVFLLLNLGDVRYGTLFYRDPKSLPSRSFTLPHPSADTTKAWAGKELPPLEELIANYGDATNTSWLDERFEIWRHGSGAAVGYVKQGKFAMITGDPLCDRGQYEEVVPAFVEFVTKDLKLTPVWMLVSNKVQELLGRRIGWRTLSCTVEQRADADQHTTPDGRAARRVKREGIKIHEVKPNEDFMKRTDQAIEAWKEKRKSKKQVHLTEIRPWIDQAHRRYFAAEKDGKVLCMVVLAQLAPRYGWQVKWALDFPDAPNGTIEVLVEYALSCISGPVTFGAGVSDRLVPGEHLHGVRAKFLSKMYAGIVKSLGLGKKAEFRDKFGVLGEQVYICYPRRGVTLFDLKEIVRFFMDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q935</accession>
    <name>E3Q935_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_01709</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091234.1">
        <property type="nucleotide sequence ID" value="XM_008093043.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q935"/>
    <dbReference type="GeneID" id="24407074"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01709"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_13_1"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000090">
        <property type="entry name" value="MFS sugar transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF37">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="50"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="79"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="176"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="303"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="327"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="362"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="400"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="431"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="12"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ27214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="505" mass="55362" checksum="0A82779E38FB46F3" modified="2011-01-11" version="1">MALPPKWYQFLVSVFASLGSFNYGYDLGVIASAIASASFKTKFGDDPNEIGAVVSVFTGGGFIGAGLAGPTGDRLGRKLTILIGATIFVLGGALQAGAQSLAFLYAGRALAGVGVGFLTMIIPMYQAELCHPSIRGRVTALQQFMLGVGALCAAWISYGTYVGFAEDDNNQWRVSLGIQCIPGGILALLILLFPESPRWLIDHGRLDEGLQTLAKLHAHGDINDAWVRAEFDQIQESIALEHEGSAKSYKELFTDKSCFRRLFLACALQGSIQMTGVSAIQYYSVAIYEKIGIAGDETLRYQAISSVIALVAQFLCMMLIDKTGRRWPLILGNLGNCVTFIIATILLAKFPPGSEHASGSAAWGFIAMTWLYNFSFSATCGPLSWIIPAEIFDMKTRSKGVSIATMTSYAFNTLIGQTTSVALDDKSGIGWRWYILFIVCNFTNAIFFWAFLPETARRPLEEMRYLFTEASLFIPTLDMKTVETHDLERRVEAVEQKREHETEHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q953</accession>
    <name>E3Q953_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_01727</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091252.1">
        <property type="nucleotide sequence ID" value="XM_008093061.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q953"/>
    <dbReference type="STRING" id="645133.E3Q953"/>
    <dbReference type="GeneID" id="24407092"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01727"/>
    <dbReference type="eggNOG" id="KOG1039">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018150_0_0_1"/>
    <dbReference type="OrthoDB" id="411372at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045072">
        <property type="entry name" value="MKRN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11224:SF10">
        <property type="entry name" value="IP09428P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11224">
        <property type="entry name" value="MAKORIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="57"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="85"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="57"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="85"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="18"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="185"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="371"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="440"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="574"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="190"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="457"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ27232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="597" mass="62857" checksum="D1BEB8B59A088A6A" modified="2011-01-11" version="1">MPSTNGSEYRHMRSGSLNIQQQNGHPSPIMSPMPSTASTASASASAARFDGPRSPPNTSHVPCKFFRQGACQAGNACPFSHDLGAAAENICKYFAKGNCKFGPKCANIHVLPDGRRINYGKNGVTIGTSPIALGGRINPTSAANYHPTSALTSGLYREGVPPYTSAYPYGDERQNHLGGPPNLENGLPTIDTTYSHPGSNYGSPRDEDASRFGLGLSPINANGLSVLDAPLPASFDSQGMSNAARFPAAPWPSSVPSKFGIESPTPSLSNAKDSRTSETLKMLHTSAFGGSEYLAAANVTASSSPPSQPEEYFGKRTMHSSRYAKPKMMSSSMPKTTAVDHDWEADFGFLEEDCVPHNLQDLLTPTEKARRGSLRTVDGEPGSENATKFGSPIGGASPSRWGPLFQRQKEDELGTHKHGPSAFGHVGSPLRNSLLSNEMGHGGAMARPIGSRAGSEPMSTLTQQLQRTRLGDDGSASPHLHPLAAAGRASSIGGAGPIGKERDRIMERHVSSGSISSSVTGRYTTPIDEEDPAFVFNMEDEEDQSPARLRKNGSAGFGIGGGWSYANALSNKGAASASGLAKDQREPSVSVETVGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAZ1</accession>
    <name>E3QAZ1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Required for hyphal anastomosis</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_03173</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ28029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092049.1">
        <property type="nucleotide sequence ID" value="XM_008093858.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAZ1"/>
    <dbReference type="STRING" id="645133.E3QAZ1"/>
    <dbReference type="GeneID" id="24408538"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03173"/>
    <dbReference type="eggNOG" id="KOG3680">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003184_0_0_1"/>
    <dbReference type="OrthoDB" id="18234at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007010">
        <property type="term" value="P:cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040185">
        <property type="entry name" value="Far11/STRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021819">
        <property type="entry name" value="Far11/STRP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012486">
        <property type="entry name" value="Far11/STRP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13239:SF4">
        <property type="entry name" value="AT25231P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13239">
        <property type="entry name" value="PROTEIN REQUIRED FOR HYPHAL ANASTOMOSIS HAM-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11882">
        <property type="entry name" value="DUF3402"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07923">
        <property type="entry name" value="N1221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01293">
        <property type="entry name" value="DUF3402"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01292">
        <property type="entry name" value="N1221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Far11/STRP N-terminal" evidence="2">
        <location>
            <begin position="103"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="Far11/STRP C-terminal" evidence="3">
        <location>
            <begin position="505"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="438"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="572"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="648"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="777"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="657"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="784"/>
            <end position="793"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ28029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1022" mass="114411" checksum="B50397C5CA1D4CA5" modified="2011-01-11" version="1">MNSLWPSRPVNEGAPAEKEPPPTGDVADAVVADVGPDASNPPPPPAARPSLQRNSSAPSPVPAPAPDPPAPMPPAPSEQPQPTDSLSLLQLRRIVAEFSRGEPVAYDFVYNDMGSHDEEIDEWFVYQFWQWVRLNAAQRAFEWQWQHEYDVQTTWEETEHQTRVKFTQDALYGLQVKDPAQRSASIGKVLYLVLGRWGDTSTPATVGDRRSAASATQLEAIRSSITFLTSLNGIATVWKALQDCFDVFWSDDPRLVQPGGAQEAQDELINLMTIMYVIIQEALSFPKELETTRSELLSLKPGLVDFMSLAASKLRWDDGNLMPSSQIFLLFWKTILLVFGGTQEIDEVKKATSESPNAKSKDVITASPLDYHVFRQELTSKYPAYVPPRTLIPLEPENTTLLPPLPNHPTRTSAAMGFVPGPPNPQSSGASILHQPVHIATPAPSPPPSPGVGGKGGKKQNYQTNQNFPFMYPPLDATSNSAGGKGGAGLQELLVGRRWEGSDIPASILEAGELFSRRVRTTRATRQLWRERESFLKFERGWEADDSDDDVDDLDLEGLSLEEKQEIAALKAETRAEERREAQLSMREPEIDRGPAAERVNEEVKRRLLAVESFYKESLPHLQSLVIVLLRPILLNVTAVLSQPAAAQQHPSMAGRGANGMNGGPGPNRQQQSQDPSAQSGPPEPPEMTPEEVDAARSREITTKAITAILLLLLKWLRISHVLKFEYMTQLLLDSNYLPLVLKLFAHQDVQQVVDSKTDRLENSFFHFCNLRSKFKDKPPVQAEPEEESEDEAAPPPIKRRRSPPRATTAATRDSDNSAKLDGQAAVRPEVDELGYPVNDLPAEPITDFSRRNFFSLINYLRIMQKICKHKAHRNLLLVQYKSANILRKSLKIPQPELRLYTLKLFKNQVPYCGRKWRQSNMRVITAVYLHCRPELRDEWLAGSDVDAEVDSALPLEQALRSLTHWYNMHRYPEKIAVELRAALREEQDFFTRELEKLDMNWADVGAEDGANSEWAEAAGWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBK1</accession>
    <name>E3QBK1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Rhomboid family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_03484</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092360.1">
        <property type="nucleotide sequence ID" value="XM_008094169.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBK1"/>
    <dbReference type="GeneID" id="24408849"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03484"/>
    <dbReference type="eggNOG" id="KOG2980">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1855118_0_0_1"/>
    <dbReference type="OrthoDB" id="418595at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S54 rhomboid" evidence="6">
        <location>
            <begin position="18"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ28340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="138" mass="14747" checksum="3D41C4F92C820FC7" modified="2011-01-11" version="1">MSTYKTYGESFYQLGISPIRFILLAMGSGLAASYAHIFNARHRRGAKNMVERTAVGASGVLTGLGTALACMFPTLEVRLSGANQMLPLRVVVLGMFAVDAYCLGTDRETGVGHAGHIGGALFGLTYFLWRKATGARNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBL2</accession>
    <name>E3QBL2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ribosomal L18p/L5e family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_03495</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL18 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092371.1">
        <property type="nucleotide sequence ID" value="XM_008094180.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBL2"/>
    <dbReference type="STRING" id="645133.E3QBL2"/>
    <dbReference type="GeneID" id="24408860"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03495"/>
    <dbReference type="eggNOG" id="KOG0875">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056222_1_0_1"/>
    <dbReference type="OrthoDB" id="1618453at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008097">
        <property type="term" value="F:5S rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00432">
        <property type="entry name" value="Ribosomal_L18_L5e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.100:FF:000002">
        <property type="entry name" value="60S ribosomal protein L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01337_A">
        <property type="entry name" value="Ribosomal_uL18_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005485">
        <property type="entry name" value="Rbsml_uL18_euk_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057268">
        <property type="entry name" value="Ribosomal_L18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025607">
        <property type="entry name" value="Ribosomal_uL18_C_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23410:SF12">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23410">
        <property type="entry name" value="RIBOSOMAL PROTEIN L5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14204">
        <property type="entry name" value="Ribosomal_L18_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17144">
        <property type="entry name" value="Ribosomal_L5e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00058">
        <property type="entry name" value="RIBOSOMALL5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53137">
        <property type="entry name" value="Translational machinery components"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL18 C-terminal eukaryotes" evidence="7">
        <location>
            <begin position="229"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="243"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ28351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="290" mass="33348" checksum="7A39BB826419275F" modified="2011-01-11" version="1">MSRARFQTKYKRRRQGKTDYYARKRLITQAKNKYGAPKYRLVVRFTNRDIIMQIVTSEITGDKVFCAAYSHELPAYGITHGLTNWAAAYATGLLIARRTLSKLGLDKTFTGVEEADGEYTLTEAAETDDGERRPFKANLDVGLHRTSTGARVFGAMKGASDGGILVPHSEKRFPGYDMESKELDAETLKNYIFGQHVAEYMETLADDDEERYKSQFQQYIDDDVEADGLEELYSEAHAAIREDPWKKPERANTKTKEEWKAESKKYKTQRLTKEQKEQRVKERIAELRAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBR9</accession>
    <name>E3QBR9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">WD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_03552</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092428.1">
        <property type="nucleotide sequence ID" value="XM_008094237.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBR9"/>
    <dbReference type="STRING" id="645133.E3QBR9"/>
    <dbReference type="GeneID" id="24408917"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03552"/>
    <dbReference type="eggNOG" id="KOG0265">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_57_2_1"/>
    <dbReference type="OrthoDB" id="1068471at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024977">
        <property type="entry name" value="Apc4-like_WD40_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052234">
        <property type="entry name" value="U5_snRNP_Component"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44006">
        <property type="entry name" value="U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 40 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44006:SF1">
        <property type="entry name" value="U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 40 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12894">
        <property type="entry name" value="ANAPC4_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="60"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="103"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="145"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="194"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="229"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="279"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 4-like WD40" evidence="6">
        <location>
            <begin position="289"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="321"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ28408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="356" mass="38537" checksum="DC5B705614821991" modified="2011-01-11" version="1">MSAEKRPASDEPGAGQMIVKRQNVGSSTGALARLNASGNSTALVQTTPRTSNLQAPVMELSGHSGEVFAAKFDPTGNFIASGSMDRSILLWRTYGDCENYGILTGHRGAVLDLQWSRDSKIIYSAAADTHLASWDIENGTRIRRYIGHDEIVNTMDISKRGEGMLVSGSDDGTIGLWDPRSKHAVDHIETEFPITAIAMSEAGNEVYSGGIDNDIKVWDLRKKSVVYSMLGHQDTVTSLRVSPDSQSLLSFAMDSTVRTWDIRPFAPTDRHIRTFDGASVGLEKNLIRASWNSDGKKVAVGSGDGTATIWSSETGKLMYKLPGHKGTVNCVEFAPGTEPIVLSASSDRNMLLGELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QC96</accession>
    <name>E3QC96_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphatase PP2A regulatory subunit A/Splicing factor 3B subunit 1-like HEAT repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_03628</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the phosphatase 2A regulatory subunit A family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092504.1">
        <property type="nucleotide sequence ID" value="XM_008094313.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QC96"/>
    <dbReference type="STRING" id="645133.E3QC96"/>
    <dbReference type="GeneID" id="24408993"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03628"/>
    <dbReference type="eggNOG" id="KOG0211">
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    </dbReference>
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        <property type="term" value="C:nucleus"/>
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        <property type="term" value="C:protein phosphatase type 2A complex"/>
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        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
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        <property type="term" value="P:establishment or maintenance of cytoskeleton polarity"/>
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        <property type="term" value="P:meiotic centromeric cohesion protection in anaphase I"/>
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        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
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        <property type="term" value="P:negative regulation of septation initiation signaling"/>
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        <property type="project" value="EnsemblFungi"/>
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        <property type="term" value="P:regulation of translation"/>
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        <property type="entry name" value="Serine/threonine-protein phosphatase 2A regulatory subunit A alpha isoform"/>
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    </dbReference>
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        <property type="entry name" value="Leucine-rich Repeat Variant"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="HEAT_type_2"/>
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        <property type="entry name" value="PP2A/SF3B1-like_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051023">
        <property type="entry name" value="PP2A_Regulatory_Subunit_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10648:SF4">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2 (FORMERLY 2A), REGULATORY SUBUNIT A, BETA ISOFORM-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10648">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF22646">
        <property type="entry name" value="PPP2R1A-like_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="9"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="13"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="90"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="206"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="247"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatase PP2A regulatory subunit A/Splicing factor 3B subunit 1-like HEAT repeat" evidence="4">
        <location>
            <begin position="280"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="286"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="325"/>
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        </location>
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            <begin position="364"/>
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        </location>
    </feature>
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            <begin position="403"/>
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        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="520"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038332"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF22646"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EFQ28484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="622" mass="69513" checksum="D39C8C9E05DD97BA" modified="2011-01-11" version="1">MADAPNTQDELYPIAVLIDELKHDDVLLRLNAIHRLSTIALALGAERTREELIPFLDESVEDEDEVLVALSGELGNFIEYVGGPQWGHVLLSPLENLAAIEEPVVRDKAVESLNKICEELSSQQVEEYFIPLTIRLSKADWFTSKVSGCGLFTTPYKKVSPPVQEELRKQFGQLVHDETPMVRRQAATNLAKFVKEMPAAIVVEEMIPLFQHLAQDDQDSVRLLTVEILISIAEVVPKEQQSSHGVLLTSLRNLIEDKSWRVRYMIADRFEKISKAVDEEVVSRDLVPSFVKLLKDNEAEVRTAIAGQIPGFCALVDRTVLLNDIMSSVEDLVSDTSQHVRAALGTQISGLAPILGKQETIDHLLPMFLQMLKDEFPEVRLHIISKLELVNQVIGIDLLSQSLLPAIVQLAEDKQWRVRLAIIEYIPLLASQLGVKFFDEKLSNLCMSWLGDTVFSIREAATHNLKKLTEVFGVEWASEAIIPKVMAMGNHPNYLYRMTTAFAITTLASVVSLDVIADKILPMLDKLVDDEIPNIRFNVAKTYGVLIDVLRRLPEEGTIYSLEKEGNSFTASPRGMELIQTRVIPKLEKLQKDDDVDVRYFATTSANSVSGPSTGEPMNTSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCJ2</accession>
    <name>E3QCJ2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">25S rRNA (uridine-N(3))-methyltransferase BMT5-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_03724</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EFQ28580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008094409.1"/>
    </dbReference>
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    <dbReference type="STRING" id="645133.E3QCJ2"/>
    <dbReference type="GeneID" id="24409089"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03724"/>
    <dbReference type="eggNOG" id="KOG4174">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070042">
        <property type="term" value="F:rRNA (uridine-N3-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019446">
        <property type="entry name" value="BMT5-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538:SF26">
        <property type="entry name" value="FERREDOXIN-FOLD ANTICODON-BINDING DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538">
        <property type="entry name" value="PHENYLALANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10354">
        <property type="entry name" value="BMT5-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="25S rRNA (uridine-N(3))-methyltransferase BMT5-like" evidence="2">
        <location>
            <begin position="74"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="25S rRNA (uridine-N(3))-methyltransferase BMT5-like" evidence="2">
        <location>
            <begin position="156"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
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        <location>
            <begin position="126"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="330"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ28580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="369" mass="40816" checksum="C99363CC782D75D0" modified="2011-01-11" version="1">MAKKRKLGSVSHKNHFVDSGKRKNGPGVPAQNSKKKNSQSVHAADSDAKKKKQQQQYHQNQEPVIPFAPEDSILLIGEGDLSFAASLAAHHGCRNVTATVLEKNERELLEKYPHAAENIALINGASPSKLADSRPTEDGGNDAEDEGEGADDTAADEKEELDEDDDEKYKPPVANNNKILYNVDARTMKPFTRKSAPNHRGFHMAAPSKQGIFKRILFNFPHVGGKSTDRNRQVRYNQELLVAFFKSAIPSLAPGGTIVVTLFEGDPYTLWNIKDLGRHAGLQSLQSFKFHPKAYPGYKHARTLGVVREKKTGEASGAAWKGEERPARSYVFMRKDEAPEEVPGKKKRKRGGDESSSEEESEVDEGFDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCP4</accession>
    <name>E3QCP4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CRIB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_03776</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092652.1">
        <property type="nucleotide sequence ID" value="XM_008094461.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCP4"/>
    <dbReference type="STRING" id="645133.E3QCP4"/>
    <dbReference type="GeneID" id="24409141"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03776"/>
    <dbReference type="eggNOG" id="ENOG502SQJB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_328775_0_0_1"/>
    <dbReference type="OrthoDB" id="5237293at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000095">
        <property type="entry name" value="CRIB_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50108">
        <property type="entry name" value="CRIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRIB" evidence="2">
        <location>
            <begin position="231"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="728"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="770"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="832"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="105"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="134"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="376"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="482"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="733"/>
            <end position="755"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ28632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="883" mass="96662" checksum="3808DE784D51669B" modified="2011-01-11" version="1">MWSTAPLPYYSAYKPSRRHEKAATGDKDSAPPSSINIRQQQAPLSLLSTQQHHHHHHHHHQHYHPDHVTDLFEPALDGPPSPERIRSLSKQMRRASAADKHKSHATTSSGSTSSLLSHNSDRSWEHTLETITLSRRSSGRSTSSNMQLRDRPESVQLFGKSIFNRRARLKRESTSNQSSSEASLYSGELALDGPFSTTKDHFIPSIFGRRRTLRQDDLDATDSAMGRKLQISGPYNFQHVTHTKRDHLPDLQRGSRAELVTEFSAIRAGQRPTTGQPRGFEVEDLHFANFSSEALHTQRATAPTSEPRAEPSSRPLILTRRLAKRTRSQEQLRPSPPRPAPPRPPRSPIREEPMSPTLPASPPPPPRSSSRIATRYTASQDSIATTDSNPERPQTSGGSQHPGAPFDLGAEAVEPPVAAQGIPSSGEGLEAPADPPFSHAITTPDDAAWPLTASTSFSCEGALPDVPEEEEQYVPPGDSCGSLPSTRSSLRGSQSVPVLRKLAQTQDESERPLSGASDTLGSFDMSAAQIALQEVLETEEVAEASRPANWEDDIDYCYEHEAEANCDYAWDRPSLDLVRESFVESSFHDNTFLVAPLSTGLKPAPSDYADNLPALSPASQTSLNGHEAITPTIATLPVKSNFSHPRKETNYRGNGHLHVRTASQASSFKESHGFHLSPSLLIPGDFHQQMRADSDTDAFPVNIPRQNSGHFSFDEEPALTIEMPGLFSRDRASTSTTGSTSSGRSSSTGARHASTNSTWTALTRYTGSTTFEGWNPKTEGSEHSRSFSTDGLSELALGSPRGQKSTMTPLPEFEEALAMSRSTGDIRVASGRLDASQSQEYLPLSKTREFPKKHQRQRAQTLSAPPPSGQYALFPPTYCGNRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCU7</accession>
    <name>E3QCU7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable acetate kinase</fullName>
            <ecNumber evidence="5">2.7.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Acetokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_03863</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>acetate + ATP = acetyl phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:11352"/>
            <dbReference type="ChEBI" id="CHEBI:22191"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the acetokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.1" evidence="5"/>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092739.1">
        <property type="nucleotide sequence ID" value="XM_008094548.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCU7"/>
    <dbReference type="STRING" id="645133.E3QCU7"/>
    <dbReference type="GeneID" id="24409228"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03863"/>
    <dbReference type="eggNOG" id="ENOG502QSJJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020352_1_0_1"/>
    <dbReference type="OrthoDB" id="67445at2759"/>
    <dbReference type="UniPathway" id="UPA00340">
        <property type="reaction ID" value="UER00458"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008776">
        <property type="term" value="F:acetate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006083">
        <property type="term" value="P:acetate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006085">
        <property type="term" value="P:acetyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00020">
        <property type="entry name" value="Acetate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004372">
        <property type="entry name" value="Ac/propionate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000890">
        <property type="entry name" value="Aliphatic_acid_kin_short-chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023865">
        <property type="entry name" value="Aliphatic_acid_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00016">
        <property type="entry name" value="ackA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21060">
        <property type="entry name" value="ACETATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21060:SF15">
        <property type="entry name" value="ACETATE KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00871">
        <property type="entry name" value="Acetate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000722">
        <property type="entry name" value="Acetate_prop_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00471">
        <property type="entry name" value="ACETATEKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01075">
        <property type="entry name" value="ACETATE_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01076">
        <property type="entry name" value="ACETATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="5">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="215"/>
            <end position="219"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="398"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="5">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="5">
        <location>
            <position position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ28719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="415" mass="45126" checksum="D68C17EB347DEF05" modified="2011-01-11" version="1">MKVILAINSGSSSVKISVYSAEPNRSPLQIAEAAVSGLTAPPAQVTYTRGGVEVKRKEDLEDDLSTQADAFKVLLKLLIEDSELPQIKKKSDIALTCHRIVHGGDYPSSQIITRDTYHHLEELSDLAPLHNGPALDIVNSCVKQLPDAVNVACFDTQFHTTIPAHVHTYPINQDVAKKNHLKKYGFHGVSYSFITRAVSEFLGKEPKDLNIIALHLGSGASACAIRNGQSWDTSMGLTPVAGLPGATRSGSVDPSLVFHYASDVGKLSPNSTSQLHLTEAEEILNKRSGWKSLTGTTDFGVIANSDEPAHKLAFDIFVDRICAFVGSYFVTLNGNVDALVFAGGIGEKSDKLRKRVAEQCACLGFTIDDALNSKKIIDTVQEVGKDAKRRTLVCQTDEQYEMARLCTENESLWQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDD7</accession>
    <name>E3QDD7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Helix-loop-helix DNA-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_04053</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="nucleotide sequence ID" value="XM_008094738.1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
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        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040112">
        <property type="entry name" value="WetA"/>
    </dbReference>
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        <property type="entry name" value="PROTEIN ESC1/WETA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ZF-C3H1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="3">
        <location>
            <begin position="322"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="93"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="146"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="251"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="418"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="391"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="33"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="299"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="325"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="418"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ28909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="487" mass="53706" checksum="12E29A552E0EE5FC" modified="2011-01-11" version="1">MDTQRPSSQKLPAGLAGVLNPDENRDSAYFSCTDASSKHNSTASGMGTNVLSPTGSSYQSSLADKTPSPVTANMVPQPLVSPAQSNMSVASMVSPTVNGTDPRRVERPTSLDSGMAHDLMGPGSRRESVDSRINQNFHDMRLGGNSPYASHNQSTTSIQNTLNQQRNPRNGLDNLSVHRISNGYQPSNDRNPENPKIIRTAPAITGPATSNIARAAEPTKGQAWAFPEEDIQRIGPNDAYLDSRRSSIAESIASSQFTTESRLPPGQRRLDEPADFNNRLSSTSSEFPPVHHHSLQHKQIGDLRDDDAASRNGSQPYSRTPELRKSHKLAERKRRTEMKELFDQLRDLMPQERGSKASKWEILTKAISEHQRMAEVMRIVQSQNTTLAQENDGLRQDNHNLRVDIQRMQNELHSLRLQQSPTGQAPAQSQAAPPPPPSAAYQTDPYASRRELPPIRGLNGNMPNGPDSMTGVQYEAPRVNGYRAERY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDR2</accession>
    <name>E3QDR2_COLGM</name>
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        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04144</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093020.1">
        <property type="nucleotide sequence ID" value="XM_008094829.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDR2"/>
    <dbReference type="STRING" id="645133.E3QDR2"/>
    <dbReference type="GeneID" id="24409509"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04144"/>
    <dbReference type="eggNOG" id="ENOG502S0A4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089054_0_0_1"/>
    <dbReference type="OrthoDB" id="6021263at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024388">
        <property type="entry name" value="Ribosomal_mL58"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28266">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN L20, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28266:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12824">
        <property type="entry name" value="MRP-L20"/>
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    </dbReference>
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        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
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        <location>
            <begin position="96"/>
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        </location>
    </feature>
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            <end position="39"/>
        </location>
    </feature>
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        <location>
            <begin position="96"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="214" mass="23917" checksum="8E8EFF49A139C59D" modified="2011-01-11" version="1">MEARTLTRPATTLATLLRQQTAVSAPPRRGHKTFSRTKRSLNIPPHSDFLPAAPAAGDTIIYNPPSAAPSVYHTPFKFLPPSDPRRRANLSSLFANSSAATSQTTPSSSAARPLPPALNVPSRGPKPRYHLSREDVAEIRRLRAEDPGFWSVTALARKFDCSETFITICTPAPREHKERLERKLEGVKSRWGAIRTKAREDRTRRKEMLFRGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEF8</accession>
    <name>E3QEF8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sulfate permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_04408</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093284.1">
        <property type="nucleotide sequence ID" value="XM_008095093.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEF8"/>
    <dbReference type="STRING" id="645133.E3QEF8"/>
    <dbReference type="GeneID" id="24409773"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04408"/>
    <dbReference type="eggNOG" id="KOG0236">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003182_8_1_1"/>
    <dbReference type="OrthoDB" id="288203at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008271">
        <property type="term" value="F:secondary active sulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07042">
        <property type="entry name" value="STAS_SulP_like_sulfate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.750.24:FF:000024">
        <property type="entry name" value="Sulfate permease 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018045">
        <property type="entry name" value="S04_transporter_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00815">
        <property type="entry name" value="sulP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="SULFATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SpoIIaa-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01130">
        <property type="entry name" value="SLC26A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="203"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="250"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="280"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="335"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="406"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="461"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="487"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="7">
        <location>
            <begin position="570"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="738"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="805"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="811"/>
            <end position="820"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ29264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="829" mass="90671" checksum="28B9484966BD4592" modified="2011-01-11" version="1">MPSTSTKIGHGLAKVLGIKLEKPQNEEMLRGESVFSVQSSDTFVEEEPTTAEWFLELLPDGQQALDYLRSLFPFLNWIGHYNMQWFLGDLVAGVTVGAVVVPQGMAYALLAKLDPQFGLYSSFMGVVIYWFFATSKDITIGPVAVMSTVVGNLITDVQKDFPQYEGHQIASALAIIAGAIILFIGLIRMGWVVNLISLTSLSAFMTGSAISIAVGQLATLMGIKGVNTRDATYLVFINTLKNLPKTKMDAAMGLTALAMLYLLRSIFTTLAKRHPQKSKLFFFLSTLRTVFVILLYTMISWLVNMNRRSHPLFKILGNVPRGFQNVGTPKIDTNLISAFLPFLPASVIVLVIEHVAISKSFGRVNNYTINPSQEFVAIGVTNVIAPFLGGYPSTGSFSRTAIKSKAGVRTPFAGVITGLLVLLAIYALTAVFFYIPSASLAAVIIHAVGDLITPPNTVYQFWRVSPLEVVIFFIGVFVTVFSSIENGIYTTVCISAVLLLWRILRGQGRFLGKVKIHSVVGDHVIGEDHRQVIGEYGTFSASDNAARNVFLPIDHGDGSNPEVTLDSPYPGIFIYRFSEGFNYPNASHSLEYLTDYIFARTRRTNMEAYGRLGDRPWNDPGPSRKAKIAQAQMHEEENRPTLKAIILDFSSVNNVDLTSIQQLIDVRNQLDRYAAPDKVNWHIACINNRWTKRALVAAGFGYPVDRSDGLQHQWKSIFSVAEIGGSDSAAAAAEKEANEKQISSHGKSSRAVDEEVGKDSGAYDQIDPVSLGSQKDAGRKRRGVVVHGLNRPLFHVDLTSALQSAIANSEGRGHADDEAGPKSPGSSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEV4</accession>
    <name>E3QEV4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Shikimate/quinate 5-dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04554</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ornithine cyclodeaminase/mu-crystallin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093430.1">
        <property type="nucleotide sequence ID" value="XM_008095239.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEV4"/>
    <dbReference type="STRING" id="645133.E3QEV4"/>
    <dbReference type="GeneID" id="24409919"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04554"/>
    <dbReference type="eggNOG" id="KOG3007">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042088_0_1_1"/>
    <dbReference type="OrthoDB" id="41492at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1780.10">
        <property type="entry name" value="ornithine cyclodeaminase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003462">
        <property type="entry name" value="ODC_Mu_crystall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023401">
        <property type="entry name" value="ODC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13812">
        <property type="entry name" value="KETIMINE REDUCTASE MU-CRYSTALLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13812:SF19">
        <property type="entry name" value="KETIMINE REDUCTASE MU-CRYSTALLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02423">
        <property type="entry name" value="OCD_Mu_crystall"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="376" mass="40143" checksum="8B5AA1EC3C5DEA46" modified="2011-01-11" version="1">MAFTVLSDGNVKQLFQGFGPEDVALMSDVLTDAFLSYSVGQEAQYQPHRAAVVRPNGQTGLFMPATMEGGMSVKIVGLPPPSSGSTDLRCVLTVCDGTGKAVGVINAEELTAFRTSLGSILLYRYRKRTGNIVVFGAGKQALWHLRLALVLRGGDVARITIVNRSEQRASKLVERLRAMGEASGVGGTDKVAFTVIEATPDSAPGNAPLRSAVEESDVIFCTTPSTQSLFPAEWLTSGHASAKSRYIAAIGSYKLNMKEIDPAFLRAVIDTPLGAFSSVHGGRDGVIFVDSREACFLEAGELVEAEIPAEKITEVGELADKLRKADEAEAKLLRDWLENGLIVYKSVGIGIMDLSLGKAILELAGKHKIGTILPDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFK3</accession>
    <name>E3QFK3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF3108 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04785</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093661.1">
        <property type="nucleotide sequence ID" value="XM_008095470.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFK3"/>
    <dbReference type="GeneID" id="24410150"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04785"/>
    <dbReference type="eggNOG" id="ENOG502T4T2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1065635_0_0_1"/>
    <dbReference type="OrthoDB" id="4842490at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180375" description="DUF3108 domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="239" mass="26491" checksum="39729CE7BDF75047" modified="2011-01-11" version="1">MHFVLPFLWLGATLAVAQDPLAVPADFDVEQGEVQVVEGEWFNITLEQFGDTSLDSTLEKRGEMRGTMKVGRTYMDYGCDASIRKTLEGGIRALCDGNGCDGGSTWSRKVKHTEGSIPADATITVRVEGIYKDSYALDRLREGVLESVRPDTTKGYNRSWYWRQPGGWEVSGTCKMSRFANYVGLQRFDGPSQAWIKVYVDIKKPMSTVELAGWVFSNVVGPAVGNKIGHWIGKVKASH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QG07</accession>
    <name>E3QG07_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF4048 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_04986</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093862.1">
        <property type="nucleotide sequence ID" value="XM_008095671.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QG07"/>
    <dbReference type="STRING" id="645133.E3QG07"/>
    <dbReference type="GeneID" id="24410351"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04986"/>
    <dbReference type="eggNOG" id="ENOG502S19N">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016967_2_1_1"/>
    <dbReference type="OrthoDB" id="4097086at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025122">
        <property type="entry name" value="DUF4048"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13257">
        <property type="entry name" value="DUF4048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4048" evidence="3">
        <location>
            <begin position="296"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="323"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="141"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="19"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="80"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="106"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="123"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ29842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="534" mass="59158" checksum="6EE0B14D6B629E9E" modified="2011-01-11" version="1">MQSTHEIRRRASVVERPPADSSATTTTTAFTPQPAIAPRPCHFKSSEAQIETLVGEMEIPEAMTPPPPPTPSTQDRFSRASRSTSNASRNTNRLSLTLPIAPPTSDPSRPSSVATPSYPPTPVDTSALASPSDPNDFIIAIAAQERRVLEIREELARAEAELTRLKQRWTAQGTQRKREIRHEPMRPPIPQFEPSLLDDDEAASKRSVELDRRKTLLRDLQGQTGPREYRRRVLRGGHTRTLSLLSPTKPEGFAVHEDTASLKSPVLRSPPMLASAALSKRASWQPRSYNTAASPAVKQVAQDFKLSLWSFMEDIRQATVGDEPIHGVPVRPGSTDLHGRRERPYLGEQDTIKPNSSSRPRVPLNSAFDLASIDTPSKPSKPLQERPNLKPATKSTTTKAKHFSWTPLTFDSFDDNDWSNWESPQVSSAKSARWSGSTMGGSEEIVSMSDNNENATSLKKKSSITLDTSVRSDSLFDSAVLSPSRLEELLPTVVHKLSPGNLKRTANNLMDEWEKSLKENDEEEQLIDFNETTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGC7</accession>
    <name>E3QGC7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05059</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ29915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093935.1">
        <property type="nucleotide sequence ID" value="XM_008095744.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGC7"/>
    <dbReference type="STRING" id="645133.E3QGC7"/>
    <dbReference type="GeneID" id="24410424"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05059"/>
    <dbReference type="eggNOG" id="ENOG502RJK3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015560_0_0_1"/>
    <dbReference type="OrthoDB" id="5235778at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="450"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="659" mass="72892" checksum="4FFB397E8F5D8420" modified="2011-01-11" version="1">MGSVIVAATYSVALERVDASTNGAKLPALDDDDTANDDDLSPPPDNLSPVSVSNDRALEDEIVVGNRNGVAKSSPLRVVSDPEDENLADVEDEEPVVSHYPKRKRASVFDDLSEDKMESGVATTDKEGTPRSTKPARRHGLGGVKGVILGYWRDSPVPEPRGKHAVIGFIDVRDRLRTRIQQNTRFGEPVSSADYPLPPGPGGSWVTFERVVFADHLVGMDHHQVKEYVKLRTDAVEDTEEARNAAELAAAKDAIRRVEENPPPDNVVAPAIAYGAEIPDHATMPPRPDSKRRRTGNGIGTISGGPVQTPPARDMVPFHQFDPLHGTRPTRIIVGFWKGSSEEDPANRHAVYGILGQNDMFRVKVARETRDKRFVDGNFPVGAGALWIHWEEVELEPHLKSLSRAEVKEYCRVRQWQIDRGETPETRPNNEAQAVYDAQQRVAQGFNKPGLMNNMPPSAIVPQLDDDRADSPDTKVDVNPELRQSRRTETRGIRHALPDLEVRQSSRTPVQAQNKIDASARREIARIEAAQMRTERFAADREAAAAAVAAANGANIAPPPLMPQTLPKMPMQNGNGDGRRLSSLFHERDEMQRLNKVWASQEEQRSKVGGEETKFYGGIKYERKTNGPFVGKLVSQGTIISIDGEDYVEYRVLTKPSFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGD4</accession>
    <name>E3QGD4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">GLRG_05066</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Involved in pre-mRNA splicing.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the cyclophilin-type PPIase family. CWC27 subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ29922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093942.1">
        <property type="nucleotide sequence ID" value="XM_008095751.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGD4"/>
    <dbReference type="STRING" id="645133.E3QGD4"/>
    <dbReference type="GeneID" id="24410431"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05066"/>
    <dbReference type="eggNOG" id="KOG0885">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012062_14_5_1"/>
    <dbReference type="OrthoDB" id="442970at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01925">
        <property type="entry name" value="cyclophilin_CeCYP16-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000034">
        <property type="entry name" value="Peptidyl-prolyl isomerase CWC27 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF6">
        <property type="entry name" value="SPLICEOSOME-ASSOCIATED PROTEIN CWC27 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 17" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="10" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0697">Rotamase</keyword>
    <keyword evidence="8" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="16">
        <location>
            <begin position="18"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="258"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="502"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="277"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="308"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="328"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="502"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="533"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00055615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EFQ29922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="544" mass="60130" checksum="6D7C070B5A5F5DE7" modified="2011-01-11" version="1">MSAIYNLEPQPTASVILHTTLGDISVELFAKQTPLTCRNFLQLALDGYYDNTIFHRLVPGFILQGGDPTGTGNGGESIYDGGAFGGELDPWPMDERRGHNAGPTGIGFKDEFHSRLKWNRRGQLGMANESKPDTNGSQFFFTLDKADELNNKNTLFGRVAGDTIYNLAKMGEAEVTPGTDRPTYPVKITSIEILVNPFEDMVKRTRVATQAPKTVPVEKKKKRKGGKQLLSFGDDEGDAEEVPVLKKTKYDTRIVMDVDDEEPAEKKPAKAKSKSKAKVEKVGTPETQSRPDSEPAEEQKTALPKGISSDESKRDIPIRLQESPPPEPEVRNTKSALERTNEEIAALKASMKRSYQPEPVKETRKSALESMIPETSIRGRRRRPGGNGNPRDDQQALDFLKAFKSKLEQAPEGKSNGASSLDGDVAAREEKAGDEEAELCDLHFIADCQSCKAWDQAAKEDSDDEGWMSRALSFKADKLGKDLSYRKKAEEELVVIDPREKARTLQEEKKASREARSGNSGREWDKARNSKMARASALAGRGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGG6</accession>
    <name>E3QGG6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Replication factor C subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_05098</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the activator 1 small subunits family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ29954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093974.1">
        <property type="nucleotide sequence ID" value="XM_008095783.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGG6"/>
    <dbReference type="STRING" id="645133.E3QGG6"/>
    <dbReference type="GeneID" id="24410463"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05098"/>
    <dbReference type="eggNOG" id="KOG2035">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042324_5_0_1"/>
    <dbReference type="OrthoDB" id="761538at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031390">
        <property type="term" value="C:Ctf18 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005663">
        <property type="term" value="C:DNA replication factor C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031391">
        <property type="term" value="C:Elg1 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031389">
        <property type="term" value="C:Rad17 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003689">
        <property type="term" value="F:DNA clamp loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000030">
        <property type="entry name" value="replication factor C subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.272.10:FF:000002">
        <property type="entry name" value="Replication factor C subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000136">
        <property type="entry name" value="Replication factor C subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050238">
        <property type="entry name" value="DNA_Rep/Repair_Clamp_Loader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669">
        <property type="entry name" value="REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669:SF1">
        <property type="entry name" value="REPLICATION FACTOR C SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13177">
        <property type="entry name" value="DNA_pol3_delta2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21960">
        <property type="entry name" value="RCF1-5-like_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22534">
        <property type="entry name" value="RFC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="34"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00070185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ29954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="352" mass="40076" checksum="2F0ED29BB4F6317C" modified="2011-01-11" version="1">MALIVDKHRPKSLEALTYHQELSERLRSLAQSGDFPHLLVYGPSGAGKKTRIVATLKELYGPGVEKIKIDARVFQTSSNRKLEFNIVASNYHLEITPSDVGNYDRVVVQDLLKEVAQTQQVDQSAKQKFKVVVINEADHLTRDAQAALRRTMEKYSPNLRLILLANSTANIIAPIRSRTLLVRVAAPTHEQICDVLAVSAKKENWPMVKGLHMRIAQDSDRNLRRALLMYEAVHAQNEKVTDTTPIPPPDWEALISQIAREIIDEHTPSRILQVRAKLYDLLTHCIPPTTILKTLTFKLIPLIDDALKAEVIKWSAFYEHRIKMGTKVIFHLEAFVAKFMRIMEMYLMSMDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGJ1</accession>
    <name>E3QGJ1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ARS binding protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05123</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ29979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093999.1">
        <property type="nucleotide sequence ID" value="XM_008095808.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGJ1"/>
    <dbReference type="STRING" id="645133.E3QGJ1"/>
    <dbReference type="GeneID" id="24410488"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05123"/>
    <dbReference type="eggNOG" id="ENOG502QV85">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014337_0_0_1"/>
    <dbReference type="OrthoDB" id="2104370at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018562">
        <property type="entry name" value="ARS-binding_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42048">
        <property type="entry name" value="ARS-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42048:SF1">
        <property type="entry name" value="ARS-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09441">
        <property type="entry name" value="Abp2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="700" mass="76946" checksum="1B760BE3C7858AC4" modified="2011-01-11" version="1">MEPHHHHHHHQQQQQRQQQQQQQHKTAAAAAAAVTTSVPSTTSTPANSIGRPALPDRDVTAETIEDAYVNFILHCNPAVPPETDAAALREAFRVPPRSGGKSFSTFTLFQLIRQLETKEIKTWAELALKLGVEPPDQDKGQSSQKIQQYAVRLKRWMHSMHVDAFFEYLMDHPHQYWIGIPNDPNPVCEAGRDGVLAEDDMALRALLPQIRPRRGRKRPDEDESSRSPSQRPRLDSPLVENEYAPNLAETSGPWSAHPDGRASFGKPDSSRLSANSALASAWPPVHDSPLTAFTQGPMSALTPSTRSGGFWGDAEPGSAITPSRPKASTRRHGAKVVSSAWRSSGPGGTGKTRGRPPTNKTNVDGLFVAFSAEKSPLKGPSPETKSDPGPIKFPGSIPNNVSPTIPPDIVHAPPMTRPGKPSISLQVPQRAGGAVRLATPPPPVVVINADPAQHIPNPTVPITRAPSATLKTDSGNAPPGTTPCMNLHEQSVPRMQLIAQDSDGPNSTNDLSAGMFENMEDRTNIDEVVGYLANETLNGDWFDAQDNPIDKCSIAEAYAIVHTMLERMWQTAPNQDVFLLNLSALVGGRTLLPGSRLQCKREEELEDRTTYSCNWQFRLGSIRGNYTMCHTTTYDRWRRPEEMVEKPSVKRTAEAESEWEKKYRDLLVLSEKRGKEIQSLRAGITMQLNKTFDASKDLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGV5</accession>
    <name>E3QGV5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein-serine/threonine kinase</fullName>
            <ecNumber evidence="8">2.7.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_05237</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + ATP = O-phospho-L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23052"/>
            <dbReference type="Rhea" id="RHEA-COMP:13689"/>
            <dbReference type="Rhea" id="RHEA-COMP:13690"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the PDK/BCKDK protein kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="8"/>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ30093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094113.1">
        <property type="nucleotide sequence ID" value="XM_008095922.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGV5"/>
    <dbReference type="STRING" id="645133.E3QGV5"/>
    <dbReference type="GeneID" id="24410602"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05237"/>
    <dbReference type="eggNOG" id="KOG0787">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023861_5_1_1"/>
    <dbReference type="OrthoDB" id="241648at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004740">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010906">
        <property type="term" value="P:regulation of glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16929">
        <property type="entry name" value="HATPase_PDK-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000065">
        <property type="entry name" value="[Pyruvate dehydrogenase (Acetyl-transferring)] kinase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.20">
        <property type="entry name" value="Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036784">
        <property type="entry name" value="AK/P_DHK_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018955">
        <property type="entry name" value="BCDHK/PDK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039028">
        <property type="entry name" value="BCKD/PDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947:SF3">
        <property type="entry name" value="[PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10436">
        <property type="entry name" value="BCDHK_Adom3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69012">
        <property type="entry name" value="alpha-ketoacid dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="10">
        <location>
            <begin position="303"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="110"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="135"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ30093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="437" mass="49881" checksum="67E79E7AB2B273B6" modified="2011-01-11" version="1">MSWKKTDRLMDTIRHYASFPATGVSLRQMVQFGEKPSVGTLFRASQFLAEELPIRLAHRVQELDELPDGLNDMPSVKRVQDWYAQSFEELTQLPRPDLDKTTRERLMKPAKSYGKGSMLSEATRNPSIEDGQYASLPQSNGNGWSKQKNVAARRYFAMVDDTGDWPAELRLYNERFAKALHGIKRRHDGVVTTMAQGILEYKRKRQRMQIDHNIQSFLDRFYMSRIGIRMLIGQHIALTDQSHHRDPSYVGIICTKTNVQDLAQEAIENARFVCEDHYGLFEAPKIQLVCNPNINFMYVPGHLSHMLFETLKNSLRAVVETHGQDKQEFPVTKVIVAEGKEDITIKISDEGGGIPRSSIPLVWTYMYTTVDRTPNLDPDFDKSDFKAPMAGFGYGLPISRLYARYFGGDLKLISMEGYGTDVYLHLNRLSSSSEPLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHN3</accession>
    <name>E3QHN3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_05515</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697349">
        <property type="protein sequence ID" value="EFQ30371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094391.1">
        <property type="nucleotide sequence ID" value="XM_008096200.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHN3"/>
    <dbReference type="GeneID" id="24410880"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05515"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_12_1"/>
    <dbReference type="OrthoDB" id="5296287at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF43">
        <property type="entry name" value="QUINATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G16230)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="122"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="184"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="278"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="320"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="347"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="379"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="414"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="447"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="13"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="496"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="506"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ30371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="525" mass="57377" checksum="C1499743C0C0C1E8" modified="2011-01-11" version="1">MVQLNINPYYLLTILVISCGSIPKGYDEGGFSAATGLPSFKNDFGLVASAWKGDESGLADRKANISSFGVLGAAFGSLIALAVNDRLGRLRSWQLLVAVWITGTLMQVFSSGILGLMLFARIWGGIGAGGLTVVAPLYLSEIAPAKSRGMVVSIYMVVLLSILTIGFFVNYAANATLAATRMQYRLVIAIPLIPTGLAFIASFFLDDTPRWLASQNRGEEALAALAKLRHADPSDRALAAEYDEIHEQIRNRNQILAESSTWSIAKDIATIPTYRTRFLLGAVMQTVAQWSGGNGITYYIPDIFQYAGVVGDNTSLITSGAYGVVKLVFTMIFTWGLVDVFGRRRCFIAGLFLQCITHVYMAIYMSVWVGGGNKSASDAAIASVFVYAVGWSIGLCTVQYLYGTEIYPTRIRSVCYATNMTLHWFFQFAVVRVTPNMFVSLDVWGAYVFWACICAAGLVILGLWAPETKGIPMERMEELFSGPWWMGWRAGVDLESSETTPFGKDGSTRNDSKEGHLAQDRKTDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHV7</accession>
    <name>E3QHV7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Peroxidase</fullName>
            <ecNumber evidence="10">1.11.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_05589</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 a phenolic donor + H2O2 = 2 a phenolic radical donor + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:56136"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:139520"/>
            <dbReference type="ChEBI" id="CHEBI:139521"/>
            <dbReference type="EC" id="1.11.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the peroxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.-" evidence="10"/>
    <dbReference type="EMBL" id="GG697349">
        <property type="protein sequence ID" value="EFQ30445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094465.1">
        <property type="nucleotide sequence ID" value="XM_008096274.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHV7"/>
    <dbReference type="STRING" id="645133.E3QHV7"/>
    <dbReference type="GeneID" id="24410954"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05589"/>
    <dbReference type="eggNOG" id="ENOG502QT8W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041038_0_1_1"/>
    <dbReference type="OrthoDB" id="2113341at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140825">
        <property type="term" value="F:lactoperoxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000823">
        <property type="entry name" value="Peroxidase_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31517">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31517:SF48">
        <property type="entry name" value="PEROXIDASE 16-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00461">
        <property type="entry name" value="PLPEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 10 12" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006991296" description="Peroxidase" evidence="10">
        <location>
            <begin position="26"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="11">
        <location>
            <begin position="14"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ30445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="263" mass="27947" checksum="125CF1C75F0270C1" modified="2011-01-11" version="1">MQFSRRCTSFLAASLSVTTICNAHARSCPPVWTEIAADLKGSFAGCPSEARQAIRAAFHDCFPGSCDGSLILANECFDREENMQMQPICDILGEKAAAYNVSTADMIQAAAAFGVAACGGPKIYFLVGRKDSSVPSTEGVLPTQDSDAATQITAFKKKGFSATDLVALVGAHSAGRSLQELSFDSTPEELDSTVFYPETLEETTPTSLGSDVALGNDKATKHIWKRFGASQTQWNSAFKLAMGKMSIMGNNLGKLTDCSKLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>E3QI73</accession>
    <name>E3QI73_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05832</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094708.1">
        <property type="nucleotide sequence ID" value="XM_008096517.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QI73"/>
    <dbReference type="GeneID" id="24411197"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05832"/>
    <dbReference type="eggNOG" id="ENOG502T5RP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_195446_0_0_1"/>
    <dbReference type="OrthoDB" id="4849347at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178487" evidence="1">
        <location>
            <begin position="20"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="67" mass="7346" checksum="95C9AD8B2040BE03" modified="2011-01-11" version="1">MKTTWFGLLLLQAMSLALAAAIERPNEEAEKEAARILKKPFEPLHPATGKMTVAPFHETDNTVAGKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIA5</accession>
    <name>E3QIA5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="13 14">Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase</fullName>
            <ecNumber evidence="3 14">2.7.4.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">GLRG_05864</name>
    </gene>
    <organism evidence="20">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>1D-myo-inositol hexakisphosphate + ATP = 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:37459"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58130"/>
            <dbReference type="ChEBI" id="CHEBI:74946"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:37460"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + ATP + H(+) = 1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:10276"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58628"/>
            <dbReference type="ChEBI" id="CHEBI:77983"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:10277"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Cytoplasm</location>
            <location evidence="1 14">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the histidine acid phosphatase family. VIP1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.24" evidence="3 14"/>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094740.1">
        <property type="nucleotide sequence ID" value="XM_008096549.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QIA5"/>
    <dbReference type="GeneID" id="24411229"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05864"/>
    <dbReference type="eggNOG" id="KOG1057">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000914_2_0_1"/>
    <dbReference type="OrthoDB" id="18042at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033857">
        <property type="term" value="F:5-diphosphoinositol pentakisphosphate 1-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052841">
        <property type="term" value="F:inositol bisdiphosphate tetrakisphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052723">
        <property type="term" value="F:inositol hexakisphosphate 1-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052724">
        <property type="term" value="F:inositol hexakisphosphate 3-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000830">
        <property type="term" value="F:inositol hexakisphosphate 4-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000831">
        <property type="term" value="F:inositol hexakisphosphate 6-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052843">
        <property type="term" value="F:inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052845">
        <property type="term" value="F:inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006020">
        <property type="term" value="P:inositol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032958">
        <property type="term" value="P:inositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030643">
        <property type="term" value="P:intracellular phosphate ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000036">
        <property type="entry name" value="Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11950:FF:000002">
        <property type="entry name" value="Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013651">
        <property type="entry name" value="ATP-grasp_RimK-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037446">
        <property type="entry name" value="His_Pase_VIP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040557">
        <property type="entry name" value="VIP1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12750">
        <property type="entry name" value="DIPHOSPHOINOSITOL PENTAKISPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12750:SF9">
        <property type="entry name" value="INOSITOL HEXAKISPHOSPHATE AND DIPHOSPHOINOSITOL-PENTAKISPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18086">
        <property type="entry name" value="PPIP5K2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08443">
        <property type="entry name" value="RimK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="VIP1 N-terminal" evidence="18">
        <location>
            <begin position="246"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp fold RimK-type" evidence="17">
        <location>
            <begin position="466"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="44"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="103"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="589"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="848"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1052"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1152"/>
            <end position="1205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1452"/>
            <end position="1488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1500"/>
            <end position="1529"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="967"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="105"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="120"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="209"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="625"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="657"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="16">
        <location>
            <begin position="707"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1062"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="1152"/>
            <end position="1199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="1452"/>
            <end position="1461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="1475"/>
            <end position="1485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00071668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU365032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF08443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF18086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EFQ30720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1529" mass="168861" checksum="942AF2512F936CE8" modified="2011-01-11" version="1">MPPPSSLPLKSSRTSLCRRRRESNNSLDAWSDSALQFADADDLDTPRLVSGSSQHHPDSTAPYRPLPDSALTTRTSFSSESEQKRTSVSSIFSVYSLASARGVLPSSSAPATQSSAASTNGSDSGPSRSVSGIMSSGKPVTNASQPGAEVSNVTVTTSSNGQHGNSAPGAHHLTPRDTNTHAHHDVVKRPRPERPQPTRSRSRNKRRLSASTGASSHSPSSDRGLFHSNTSNKEKEEVKPAPWGVIGVCALDVKARSKPSRNILNRLIANREFDVVVFGDKVILDEEVENWPMCDYLISFYSDGFPLDKAIAYVKARKPFCVNDVPMQKILWDRRLCLNILDRIGVPTPGRIEVNRDGGPKILTPDTAKHIKEVTGITLDPEELGYNRLPRKVELLDDGDILSVDGTLLKKPFVEKPVSGEDHNIIIYFPKSTGGGARRLFRKIGNKSSEYDPDLNIPRAILEPENSYIYEKFMRVDNAEDVKAYTVGPNYCHAETRKSPVVDGVVRRNTHGKELRYVTALDPEEKEIASKISTSFGQRVCGFDFLRAGGKSYVIDVNGWSFVKDNDDYYDHCANILKDVFVKERLRRGGVTSPAPSPSPSDIVDPLASRGKDKESQPIPVPPAQNKSVTSISAISEKLPQEPKHAPTSVATQKSDSALNSSVTSSCTSPTLPPPPPLVDPVVASVPSTTGSATPSAAPSLKGEGTGPPPEETPVPPPPPKHSWKLKGIVSVIRHADRTPKQKYKFTFHTAPFIELLKGHQEEVLLIGEAALASVLQAVDVALRAGVEDHNKLKSLRNVLVKKGGWAGTKVQIKPMFRKKKTEEIAVSSGDELSQVLKEGVETDFAEKPEDAVAKTENSSPVRMPPKRHDSLSGVTMSRITAAEESLVLDKLQLIVKWGGEPTHSARYQAQELGENMRNDFNLLNRDVLDEVHVFSSSERRVTTSAQIWASAFLDRKDLPEDFITIRKDLLDDSNAAKDEMDKVKKKLKGLLRKGNERPPQFAWPEKMPEPSEVQTRVVQLMNFHRRVMHYNYTKLHNGSAVASLNSAIANPGTEKPANGDSSVSAGSTSSSLSQANAVSNIQPRWCCGEDAELFRERWEKLFAEFCDGDKVDPSKISELYDTMKFDALHNRQFLEWVFTPPKAMLEEEYGIKEKESKEGSKDGKATDKASDEGKSSLDSREERRDGSGSSDKAEKSEANKSSTSVRRIFRRRSFLNGLRNAEAAPPEQYFHLYKGNTQTKAKTDARFEPLRELYQLAKVLFDFICPQEYGISDGEKLEIGLLTSLPLLKEIVQDLEEMQASNDAKSFFYFTKESHIYTLLNCIFEGGIETKIKRSTIPELDYLSQICFELYESETKAPADTPDGGEEQTFAYSIRITISPGCHVFDPLDVQLDSKHCISCAPRRSLTPHGDWMQVIRTLRAKFNQVKLPKTFLAINLSDLFSFEDHERRDSDSEGLEMKALHPKPKSTAQAAVKQKEDETKAEPELLIEAGQALASVSSVAMEPEELVSPKTRSSAEIMPQAAESSER</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIF0</accession>
    <name>E3QIF0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sulfate permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_05704</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094580.1">
        <property type="nucleotide sequence ID" value="XM_008096389.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIF0"/>
    <dbReference type="STRING" id="645133.E3QIF0"/>
    <dbReference type="GeneID" id="24411069"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05704"/>
    <dbReference type="eggNOG" id="KOG0236">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003182_8_1_1"/>
    <dbReference type="OrthoDB" id="288203at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008271">
        <property type="term" value="F:secondary active sulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07042">
        <property type="entry name" value="STAS_SulP_like_sulfate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018045">
        <property type="entry name" value="S04_transporter_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00815">
        <property type="entry name" value="sulP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="SULFATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SpoIIaa-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01130">
        <property type="entry name" value="SLC26A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="249"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="287"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="414"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="464"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="7">
        <location>
            <begin position="588"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="539"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="621"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="546"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="626"/>
            <end position="635"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ30560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="818" mass="88248" checksum="AEBF1D2945E5A159" modified="2011-01-11" version="1">MAAGKAGAVLAKILGIDLEASTRHQTRELREHVANTISPHEPYYEEDPTVKEWLLEHVPTKEGSARYVKSLFPFTTWIFRYNTRWLVSDAIAGVTLGLLAIPQAVAYALLARLSPEYGLYTSFTGAALYWIFGTSKDMAVGATAVVSLLVGKVSARVLEEHPGEFQPEEISKTLAFLAGAVLLAFGLLRLDWVIEFIPHVAISAFVTAAAITITLSQIPSLLGIDGVNSKAAAYRVLIETARGLPRIKLDAAVGLTALALLAAVKWYCERMARTQPRRRRAWEMLGSLRMTFTIVLYTLVSFLVNRGLESRDLRFRITGALPRGLTHAGPPSLDPKLISALLPDLPTTVIIIVIEHIAIGKSFGRTNNYAVQPSQELISVGCTNLFGPFLGAYASTGSFGGTAILSKAGVRTPLAGLFNAAVLLLALYALTSVLYYIPMASLAALIVHAVANLITSPDHVFRSWLASPPDVFIYFAGVFASVFTTLENGIYVTVALSAALLLLRLARSKGRFLGRVRVHRHPEHADAAAATAAAAPDDVVSDKHSVNSSQTLSHSRTASSMARLPARDVFLPLDRKDGTNPAGSFKGDNSFVYRFTEGFNYLNQAQYMDRLLEHVTRATRQTTPPHYDHPGDRPWNEAPPPPSAEADDAECPATSKPLLRAIVLDCSAVNTMDSGAVEGLVDLRTQLDRWAAPEPVEWHFAGLHSRWDRRALAVSGFGCPTAGRLGGFQPVFSLADLEGRPAALCKGRAGAITACGARDSEELSCSSLEEGGFGPEESAGTYLGAVSGINRPFFHLDLPSAVENAVKSAIRKGRYLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJC6</accession>
    <name>E3QJC6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_06108</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ30964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094984.1">
        <property type="nucleotide sequence ID" value="XM_008096793.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJC6"/>
    <dbReference type="GeneID" id="24411473"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06108"/>
    <dbReference type="eggNOG" id="ENOG502SVII">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069188_1_0_1"/>
    <dbReference type="OrthoDB" id="5207784at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="228" mass="24929" checksum="EA69FCFC7F9378C1" modified="2011-01-11" version="1">MDEPRGSTETSLPPYDAVSQPYQEVCPPTTLIIAGQSIHALTADSPPLYHLSLGISNLSDITTEVELSRVEPNKDGSGRQRHIYDLRYMRSGPGGYVKLPSDSPHYFIERASRRVPGLQDLGLKKSRLLGKACTTVLPVDIRGKTSKYSIPNFVKDSAPVFSINKDRWADAQGAPIASMHDTTEHSLIVTAALPRAQFDMLVALWCCKVWESGVANAEKVHEGIDGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJG6</accession>
    <name>E3QJG6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_06148</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ31004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095024.1">
        <property type="nucleotide sequence ID" value="XM_008096833.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJG6"/>
    <dbReference type="STRING" id="645133.E3QJG6"/>
    <dbReference type="GeneID" id="24411513"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06148"/>
    <dbReference type="eggNOG" id="ENOG502SWT1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008331_0_0_1"/>
    <dbReference type="OrthoDB" id="3251668at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="467"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="8"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="223"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="393"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="504"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="601"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1041"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="242"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="296"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="395"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="519"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="529"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="552"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="602"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="641"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="686"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="697"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="749"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="822"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="852"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="889"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="923"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="955"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="971"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1041"/>
            <end position="1060"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ31004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1089" mass="117523" checksum="77AE5FE0532B9EA0" modified="2011-01-11" version="1">MAEALLGLAPSYGDAHSGKPPIAHPDDLPRLLRRDLETKKTPTRCEHISITLEVPSTVEFAIQASDGDAQEIVDPALDGVQAHAVGGQPVKIVRAYDTIINQPHDNPAFQRAVAKHIAGILSVADESTWVVREVSRGQYGWSFTYICKDSVAMWNRQNGKTVAKPIIGDFSQKDLEPDVSGRPAFDCRGVLTIAFSKNSRTISVKYEHTPFHKTVGEMIEHFRPLPPAAPPVHLIPAGDRPKKAKTPRKRKSEANADGTPSVPKRKKRKSEANEDGTPGQPRKKRKENPDAGAGGAQEEAVGDGQTTTTAPTKADAAVQIGVHEHAVLNVPPAEAARRREVAIRLLSGSGVDPESLSAEQFSIFANQSPDLQKESLAMLVKYGAERLRIVHPSDAAASSSTTASPAPQQATTAESEADDSEVTSETPAPAKKKRRPRKSSQVAGDAEEAELIPAPAGTPLKQVSRGSCIACRRAKAKCDRAKPTCSPCGEQDVECQYPLVRKQVAKTKEDSPKTPVGNGDDDDAEAEPEPEHEPIPEHEPIPEHEPIPEPAVETEEQEPDDIETIDYTSNMPVANMITPAVEPPSQDYFNFGNNELAFTQDSSSEMSMSHGASSYPEPSATVTYTEQQTATTSYEQTSSSLTETATYTQPSADTSGYVQPTNTENAGYLHTTTDTSNLNYAQPAAESKRSTRDPTTRRSLPTEQPQQSTAENPAHPSNYTQNWHDSSPSKVTNMPSPTTIAQQHLSWKQAQAPAPAAATQQSASLGNHGQTQQTASYAAMQQQQQKYQPSPPQQVAQVAQAPKPVTPAQVSPLQAPGQAARTKSRAGHRASTHTPVNEQRPPSPQQIVQPSTQGTTDTIGTRLTTYQPCTAQTTSANTTTYPSYDYDRSNNTTSQRTTLAYTPSNIPQTRQLYSTQPQTRNKQAYGSNGASASAASSYTQPSSTAPQQSSTLQSFNTRTPPTGSQARSSTRPNNQRQHQQHQQQPQQQAPYSSYSSQTHQQPHQPDQHNWYGFGSGITGSFSSANVSGGYAARGSATTNYGAGSNVSNPNQAYQQQQHHSSVLIPGHNYAEGDNDMYELLKSSLHGPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKB6</accession>
    <name>E3QKB6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ATP-dependent (S)-NAD(P)H-hydrate dehydratase</fullName>
            <ecNumber evidence="9">4.2.1.93</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP-dependent NAD(P)HX dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_06448</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(6S)-NADHX + ATP = ADP + phosphate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19017"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:64074"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.2.1.93"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>(6S)-NADPHX + ATP = ADP + phosphate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:32231"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.2.1.93"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the NnrD/CARKD family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.93" evidence="9"/>
    <dbReference type="EMBL" id="GG697354">
        <property type="protein sequence ID" value="EFQ31304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095324.1">
        <property type="nucleotide sequence ID" value="XM_008097133.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKB6"/>
    <dbReference type="STRING" id="645133.E3QKB6"/>
    <dbReference type="GeneID" id="24411813"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06448"/>
    <dbReference type="eggNOG" id="KOG3974">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030651_0_0_1"/>
    <dbReference type="OrthoDB" id="8110916at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047453">
        <property type="term" value="F:ATP-dependent NAD(P)H-hydrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110051">
        <property type="term" value="P:metabolite repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046496">
        <property type="term" value="P:nicotinamide nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01171">
        <property type="entry name" value="YXKO-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1190.20:FF:000043">
        <property type="entry name" value="ATP-dependent (S)-NAD(P)H-hydrate dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01965">
        <property type="entry name" value="NADHX_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017953">
        <property type="entry name" value="Carbohydrate_kinase_pred_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000631">
        <property type="entry name" value="CARKD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00196">
        <property type="entry name" value="yjeF_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12592:SF0">
        <property type="entry name" value="ATP-DEPENDENT (S)-NAD(P)H-HYDRATE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12592">
        <property type="entry name" value="ATP-DEPENDENT (S)-NAD(P)H-HYDRATE DEHYDRATASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01256">
        <property type="entry name" value="Carb_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01050">
        <property type="entry name" value="YJEF_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51383">
        <property type="entry name" value="YJEF_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 9" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 9" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="YjeF C-terminal" evidence="10">
        <location>
            <begin position="8"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="178"/>
            <end position="184"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="231"/>
            <end position="235"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="250"/>
            <end position="259"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ31304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="349" mass="36687" checksum="E973949AA3D7912F" modified="2011-01-11" version="1">MSAATKDVLSRVQRMIPPMLEKFHKGQLGRVGVLGGSVDYTGAPYFSAMASARLGCDMSHVICTPGAASVIKTYSPNLMVHPLMRQTPSDAAPDGSRNAHTDAGAVAGPIIDMLARLHVLVIGPGLGRDPLMQDTVARVIRAARERSLPLVLDADALLVVQKDPALVRGYRLAVLTPNVVEFSRLCKALGVDEAEAKDSAAAGSGGGEEAKETAKVEALAKALEGVTVVQKGGKDFISNGKDTLVVDLEGGLKRSGGQGDTLTGSIATFLGWRNAYLEGLWDTGDDKMAEDELVRLAAFGGSAITRECSRRAFLRKGRSLQASDLTDEVHGSFMALFGEVDGKAGATKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKE7</accession>
    <name>E3QKE7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_06479</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697354">
        <property type="protein sequence ID" value="EFQ31335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095355.1">
        <property type="nucleotide sequence ID" value="XM_008097164.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKE7"/>
    <dbReference type="GeneID" id="24411844"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06479"/>
    <dbReference type="eggNOG" id="ENOG502SJ1X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_2_0_1"/>
    <dbReference type="OrthoDB" id="3529975at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF64">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="19"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="212"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="250"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="36"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ31335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="370" mass="40366" checksum="A7C586F42FC21F98" modified="2011-01-11" version="1">MVAWTYNTPTDTPTSGPHIAALCVIFISIALLLVCLRLYVRTTLVKAVGYDDCMIVISWLGACGYAVCTVIQTKWGLGITSLKNMPDQNVFHFGKLQFIGGPFYVVSLWGFKMSLLCSYLRFFPEGRYKMGTIIVAVTCTMAHIAFLLVFVFLCTPVEKQYDPSIPVDVGHCVNGVAFYLAFSSLTIVFDVLIMFLPFPVIITSQIQRRKKAVLLGLFILGVFVTVIQAIRIQTIQNLSNYLDSAPAIQWSIIETCVGIVIACVPPLAPMVKYFAAKSRSASGGSSGVSRPPKTTTPSRYVLQTWGTKRSGMQPLGAGVDRVASVAGSSATKADDSTENILDQGGITKTTDLLLTTHDTEETWPDTNNSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKJ7</accession>
    <name>E3QKJ7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Mediator of RNA polymerase II transcription subunit 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_06529</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 10">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the Mediator complex subunit 7 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697355">
        <property type="protein sequence ID" value="EFQ31385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095405.1">
        <property type="nucleotide sequence ID" value="XM_008097214.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKJ7"/>
    <dbReference type="STRING" id="645133.E3QKJ7"/>
    <dbReference type="GeneID" id="24411894"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06529"/>
    <dbReference type="eggNOG" id="KOG0570">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065214_0_0_1"/>
    <dbReference type="OrthoDB" id="10253553at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070847">
        <property type="term" value="C:core mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037212">
        <property type="entry name" value="Med7/Med21-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009244">
        <property type="entry name" value="Mediatior_Med7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044888">
        <property type="entry name" value="Mediatior_Med7_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21428">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21428:SF11">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05983">
        <property type="entry name" value="Med7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140718">
        <property type="entry name" value="Mediator hinge subcomplex-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0010">Activator</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 10" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ31385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="253" mass="28183" checksum="DE0F0B61485629F7" modified="2011-01-11" version="1">MADNPEEPSHNALSSTFPNPPPFWRQFTPENLSRIEELRKAQADKDGIAVKDLTVRLPDIPEDLMHLQPPAEPATGTWRVLGGNYTLDDKLPSLEEGEIQRLAPAHSDEKDGKPIDRAFELKKMAKSLLLNFLELVSVMATVPDDGAAKIQDLRILLINFHHLLNEYRPHQARESAIALMQSNLDRTRAETAAIRAQVDKAKRVLEGLGSIETPKAPENITSAVDGELTAKDVEAFSRAREQEVWADADVLFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKP1</accession>
    <name>E3QKP1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mannose-1-phosphate guanyltransferase</fullName>
            <ecNumber evidence="3">2.7.7.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">GDP-mannose pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">GTP-mannose-1-phosphate guanylyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_06573</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in cell wall synthesis where it is required for glycosylation. Involved in cell cycle progression through cell-size checkpoint.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>alpha-D-mannose 1-phosphate + GTP + H(+) = GDP-alpha-D-mannose + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15229"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
            <dbReference type="EC" id="2.7.7.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; GDP-alpha-D-mannose from alpha-D-mannose 1-phosphate (GTP route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.13" evidence="3"/>
    <dbReference type="EMBL" id="GG697355">
        <property type="protein sequence ID" value="EFQ31429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095449.1">
        <property type="nucleotide sequence ID" value="XM_008097258.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKP1"/>
    <dbReference type="STRING" id="645133.E3QKP1"/>
    <dbReference type="GeneID" id="24411938"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06573"/>
    <dbReference type="eggNOG" id="KOG1460">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029499_3_0_1"/>
    <dbReference type="OrthoDB" id="285674at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004475">
        <property type="term" value="F:mannose-1-phosphate guanylyltransferase (GTP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06428">
        <property type="entry name" value="M1P_guanylylT_A_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056729">
        <property type="entry name" value="GMPPB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050486">
        <property type="entry name" value="Mannose-1P_guanyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22572">
        <property type="entry name" value="SUGAR-1-PHOSPHATE GUANYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25087">
        <property type="entry name" value="GMPPB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleotidyl transferase" evidence="10">
        <location>
            <begin position="18"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="Mannose-1-phosphate guanyltransferase C-terminal" evidence="11">
        <location>
            <begin position="313"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF25087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ31429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="443" mass="48928" checksum="3A499A11880CFADB" modified="2011-01-11" version="1">MSLQVPYRGKASGESSTKAVILVGGPSRGTRFRPLSLDVPKPLFEVAGHPIIWHCLAAIDRVPGKEITEVLIIGYYEESVFRDFIKDAASEFPNLTIKYLREYEALGTAGGLYHFRDPILKGHPERLFVLNADVCCSFPLPEMLQLFHDKNAEAVILGTRVSNEAATNFGCIVSDAHTRRVLHYVEKPESQISNLINCGVYLFSTDAIFPSIKTAIKRRTDRPSRLASYPSSENLENSFIIADDDEERKNQVIRLEQDILSDFADTKSFFVYETKDFWRQIKTAGSAVPANALYLQKAWQTGSKELAEPSANIIPPVFIHPTAHVDPTAKLGPNVSIGPRVHVGPGARIKEAVVLEDSEIKHDSCVLYSIIGWGSRVGAWARVEGTPTPVGSHTTSIIKNGVKVQSITILGKDCGVGDEVRVQNCVCLPFKELKRDVANEVIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKQ1</accession>
    <name>E3QKQ1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_06583</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697355">
        <property type="protein sequence ID" value="EFQ31439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095459.1">
        <property type="nucleotide sequence ID" value="XM_008097268.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKQ1"/>
    <dbReference type="STRING" id="645133.E3QKQ1"/>
    <dbReference type="GeneID" id="24411948"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06583"/>
    <dbReference type="eggNOG" id="ENOG502S1UN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017096_2_1_1"/>
    <dbReference type="OrthoDB" id="14339at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37332:SF1">
        <property type="entry name" value="ELMO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37332">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="448" mass="48737" checksum="B4FC9E083BB8D8BE" modified="2011-01-11" version="1">MQRPGATPVSANTPFFSSSFFSSSSKSRPGTSSGEQQQQQQPQQLQPQSQIPQPQLSPFFPPPSGPNVLLKDRKNSFARKTSFSSPSKSKRRASSSGGGGNVVVTDRNVPPALPDFALAAAAKITRETDNIQSPASTDSFTRMLGRTQTGSMSLAPSDRLQPPPSATHPNMWQSSESVVLHMQMLEMANKRISTLDYLRKAHEGRVYWFNTILFDKPDLARMPSYESRKLARRATNYLLLGLSLPTIVDLYANTPIEFLRSLNNLLQEFESFQQLHSEGGSSTSSLSRARLPSMFRRQAGKSRRSASGANDIGYPADSDPASGGSYGGIGGSSSASASVMSFASSDNDLLPGEVYTHLLTPSLPFEPDFYETFATLCEVLIDVYTKILALVPTPRETSTPIAELFAKADAKVRKIIVQGVVKEFEDNSRTHIKTEMGNIGKVVLGGLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLM9</accession>
    <name>E3QLM9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_06742</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697357">
        <property type="protein sequence ID" value="EFQ31767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095787.1">
        <property type="nucleotide sequence ID" value="XM_008097596.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLM9"/>
    <dbReference type="GeneID" id="24412107"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06742"/>
    <dbReference type="eggNOG" id="ENOG502RSGG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_894314_0_0_1"/>
    <dbReference type="OrthoDB" id="4830646at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="295"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ31767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="335" mass="37490" checksum="5EC99D47024A5957" modified="2011-01-11" version="1">MEAPTQPSSPPPPKPSEAPPAFGLGRRIREFQFDMTRILPGPRLVPNLLVSDIIGFLLYAMMAPGLSSFFEEKLYDAVPLAWTVCEGLRCFLDAFREERWHQVDHAQESADRWCSYSYRTPPPRLRSYREILNRQQALRNCCGAQLRGLGTRDVVGNMLLQATLAFCWAWALLRDHVTLVWLLAAIENGCAGYRGKIETSTPPAVRRGERTMPVARGGGSDDDGGPPYWCLGRVQWQISRGHDLISKFVELDMCHVGGGAGAGAVWDETEWLSEKDGEIPADAVVDEDRLLVNRVAFSACLSWLMVSISCDFATFYLLVLLRRLRGRLEGCIWGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLT8</accession>
    <name>E3QLT8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_06970</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095846.1">
        <property type="nucleotide sequence ID" value="XM_008097655.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLT8"/>
    <dbReference type="STRING" id="645133.E3QLT8"/>
    <dbReference type="GeneID" id="24412335"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06970"/>
    <dbReference type="eggNOG" id="ENOG502RQMT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_949987_0_0_1"/>
    <dbReference type="OrthoDB" id="4814718at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="187"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="125"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="163"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ31826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="293" mass="30187" checksum="505EFD77D11B93A8" modified="2011-01-11" version="1">MATTSFSPTVPPPREADDTCGFDPFPVTSLGFPVDGALPLRCSDPLMTCSTSGSYKGCFSTIPTTCYETSTLSRPCEPDELCCGTGSNTACWTWFSLEDTRTFSLFICSTVFGVGILLPDSTMATPSSGTDPSSTTDLPGTNTDTTATASSAGTYTTATGASAATKADTAATGPTSRTPEGGGGGGISVGAIVGSVIGALALMGMLLGIVLFIWMRSRKEKKKRDAAEPEPVSPAIGPDDIIVAPYRSGARVSAPPLYDGRPSMGPGEAKSPPPRPARSPEKKKINLTEGGWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QM03</accession>
    <name>E3QM03_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cornichon protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_07035</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cornichon family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095911.1">
        <property type="nucleotide sequence ID" value="XM_008097720.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QM03"/>
    <dbReference type="STRING" id="645133.E3QM03"/>
    <dbReference type="GeneID" id="24412400"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07035"/>
    <dbReference type="eggNOG" id="KOG2729">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112942_0_0_1"/>
    <dbReference type="OrthoDB" id="434393at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003377">
        <property type="entry name" value="Cornichon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033466">
        <property type="entry name" value="Cornichon_conserved"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12290">
        <property type="entry name" value="CORNICHON-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03311">
        <property type="entry name" value="Cornichon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01398">
        <property type="entry name" value="Cornichon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01340">
        <property type="entry name" value="CORNICHON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ31891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="138" mass="16143" checksum="DBD7B61306D03CF7" modified="2011-01-11" version="1">MSGEAWLYLFAVLVNAVNLFLQVFFTIMYSDLECDYINPIDLCNRLNTYIIPEAAVHGFLTFMFLINGYWVPLILNLPLVAYNIKKIVDNTHLLDATEIFRKLNVHKKESFVKLGFHLIMFFFYLYSMIVALIRDESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMB9</accession>
    <name>E3QMB9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">SNF2 family domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_07151</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096027.1">
        <property type="nucleotide sequence ID" value="XM_008097836.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMB9"/>
    <dbReference type="STRING" id="645133.E3QMB9"/>
    <dbReference type="GeneID" id="24412516"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07151"/>
    <dbReference type="eggNOG" id="KOG1001">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_266963_0_0_1"/>
    <dbReference type="OrthoDB" id="448448at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18008">
        <property type="entry name" value="DEXDc_SHPRH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF17">
        <property type="entry name" value="HELICASE-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="403"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="912"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="1043"/>
            <end position="1193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="209"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="825"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="972"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1220"/>
            <end position="1262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="223"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="252"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="833"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="977"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1224"/>
            <end position="1262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ32007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1262" mass="143661" checksum="E5E067ABDAE3E617" modified="2011-01-11" version="1">MSSTADDHNKSARRRKGPFLDDTESDSDIDMPSHYKTPRRANRDQIQELDFFHESIEDSTNDIRNENHVLRNTGHVACPSHSAELSDLFVTKPEGQDDIALPEKDKIRIKSEPDIDEEPELMIIDHAAASSEAQAKWSVPRPPSVIDLVTAVKQEPLFNDEPMLLDLGSQSSLKSLKGRKKELESKALKGALTSSELNEMMHIMAQLSQPAKAPTTLTLPDPSPHEQAPRQKNDKRQRRKRQAPAADAAEYWARREKKEQERNAKNQGRRGGAHNAKNKTNQAKGSDSDDSDPEEKNNRQIEELLERYDAIQHRADQGDLPAAPAITATRTDDQLKQMQEAAPEYFDKVLIVKQKQELKQSTKAWGARAVHAKGGKWEVRGLITPLLNHQLIMGAWMMGRELKTTPNLPRGGILADAMGLGKTLETLSCIVGNQASESLKDAGKGATLVICPSGQMISQWMSEVKKHCNKGFSRRIVHFKAGDKMDVDSLSSFNIVFATYHQLRASTPSAKDRENMQKKLTDPDEYKNWLEEQTGVLHRIQWYRVVLDEAHCIKNHLTHAAFACCELNAKHRWAVSGTPLINASSGKFSLLILRRTLTDSFEELFSYLKFIRCSQIGDFNGYLDKYDSGPKARKRRDRLAHQVIATDMFRTQGDYFLGQPIMNLPNTHPTHQYLSLSAEEVVVFRMVERWFRNELNHDLEEGTAVVRIRFYLVMLLRLRQAATHPFLLESVMRDHFSLEDLRATKEKLEALKGGATVYSQIGPWTQRQKVRDERIPKVFEEAEKVEQERLEDARKESLEALKVRLGEYDEQDEAQTSNLQNTTITGNGAIVTDDSDEVESQDEIEEDEDGMVPQKLASSSVNPEVELDTTDPIAEDEPQLDPFGRSEFGLHFDMTKQIEYLERLKELEAVACVVCKKKPPKKPVKGRCGCYFCNRCVMAHLADKVYYALLTTRKSRTCPKCRRIIGPLKPLQTFNGDETDEERENDSDMSQESVNEKDYTRGFDYNKFQHTESCERNKKPSRFLQISDRRPNVPLTPSAKMTALKETVLRWQAEAPEDKIIIFSQFAVVMKIIGRVLESEGICFAYLSGKQNTEQRNKAVSEFQNGEEVKVLIVSLRAGGQCLNLERGNRVILMELWWNHAVEQQAFARVFRIGQSKETHFLRFVVKTPIENRMLEMQVGKILAIDNALQDETVRAPKIGLEEIASLLGRVTWREGGVMHIEPDDYDDDYEDSPRNEEEESDLDDLVVPDDVVEYEDDEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMJ6</accession>
    <name>E3QMJ6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_07228</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="8">Belongs to the xlnR/xlr1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096104.1">
        <property type="nucleotide sequence ID" value="XM_008097913.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMJ6"/>
    <dbReference type="STRING" id="645133.E3QMJ6"/>
    <dbReference type="GeneID" id="24412593"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07228"/>
    <dbReference type="eggNOG" id="ENOG502QUI0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006123_1_0_1"/>
    <dbReference type="OrthoDB" id="5365785at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.240.10:FF:000004">
        <property type="entry name" value="Xylanolytic transcriptional activator XlnR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051439">
        <property type="entry name" value="XlnR/Xlr1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47663">
        <property type="entry name" value="XYLANOLYTIC TRANSCRIPTIONAL ACTIVATOR XLNR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47663:SF1">
        <property type="entry name" value="XYLANOLYTIC TRANSCRIPTIONAL ACTIVATOR XLNR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0010">Activator</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="10">
        <location>
            <begin position="97"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="57"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="135"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="558"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="647"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="753"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="78"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="212"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="649"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="663"/>
            <end position="672"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ32084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="976" mass="105589" checksum="12DD6CA465B6EBC0" modified="2011-01-11" version="1">MLSNPLHRFSPYHGVQSSALFSNAHVPNGHSHANGLDPLAPNSHYALQQLQQHVGAHGSNPHLARGTPQSKHRQHPYGPAARSSSASGPIRRRISRACDQCNQLRTKCDGQHPCAHCVEFGLGCEYIRERKKRGKASRKDLAAQAAAQAASGGPGQGHKSPSDDNGPPSEQGESASVKNGQSSANESQQNHGGKVIDELSDDAMQQHSQRTGSLDSLGDLAGGHPPHLSTHHGMDRDHMESPTAMDLNGYGGVHGGYDRQSLGAHMMSGPSHAAYAPSQSGMSAYPEIPYAMQTQSPTAYANSAPFRIAASPISAYPLGAEATSPEWISMSPPPPAQYPSSSHIPASGYGHAAKKLRYPVLQPLLPHLGNLIPLSLACDLIDLYFASSSSAQMHPMSPYVLGFVFRKRSFLHPTKPRHCQPALLASMLWVAAQTSDAPFLTSVPSARGKICQRLLELTVSLLRPLIHTPSGDTSPVTSPVIDGVALGGLGVALPGSISMDALSGESGPFGAAGSLDDVITYIHLATVVSASEYKGASLRWWNAAWSLARELKLGRELPPTPTLSMSQPNGHEADGDVDGESELGVSTHPGAITEEEREERRRIWWLAYVVDRHLALCYNRPLFLLDLECAGLLQPMDDTAWQNGEFRPTTHNVTTDPSLRDSTTTTTTTTTTGGQQGRVRGPHFECTGHSIFGYFLPLMTILGEIVDLHHARNHPRFGVGFRSAREWDDQASEITRHLEAYEKSLRRFEQQHLTRPSMNLDDKGDVANPEGVAEHGGGGGGAIADIGTPSVHSVHTNASNRMTESDIQTKIVMAYGTHVMHVLHILLAGKWDPINLIDDNDLWISSQGFITATGHAVSAAEAINNILEFDPGLEFMPFFFGIYLLQGSFLLLLIADKLQLEASPSVVKACETIVRAHEACVVTLNTEYQRNFSKVMRSALAQVRGRVPEDLNEQHQRRRELLALYRWTGDGTGLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QN92</accession>
    <name>E3QN92_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07474</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697361">
        <property type="protein sequence ID" value="EFQ32330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096350.1">
        <property type="nucleotide sequence ID" value="XM_008098159.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QN92"/>
    <dbReference type="STRING" id="645133.E3QN92"/>
    <dbReference type="GeneID" id="24412839"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07474"/>
    <dbReference type="eggNOG" id="ENOG502QPV0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026648_0_0_1"/>
    <dbReference type="OrthoDB" id="2011986at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018810">
        <property type="entry name" value="UPF0662"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28086:SF1">
        <property type="entry name" value="CU(2+) SUPPRESSING AND BLEOMYCIN SENSITIVE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28086">
        <property type="entry name" value="UPF0662 PROTEIN YPL260W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10303">
        <property type="entry name" value="DUF2408"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="124"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="440" mass="50849" checksum="CB434592A10DDABA" modified="2011-01-11" version="1">MDTPTCPPPRDDREKEILDKLVAIRDSLQLLKQDRTTYIRSQDVLPLYDDTIEQVRQLNEFRSSDRREENRVDRVLESCFQLLSLFFMTIGRNNEAPAAYALTSTIKRLLDHLTEVNLYSAKDLESLSHTLSKLAHNVKSTENEYSPYLITLLSNRLELCEQSLANLKKRLERLEDPLPKTYEKLISILRSISLANTRAKFSSSEVQKLRSQLLEIDQQNKEGKFMTTDGRVPAGSEEVAALLEKCLQWSDVVLERKGVIPESFRPIYDVLFRIRNELEKLSITKAWSLREADLYDFQRQLDKIDESRVNGNWLDEDGKPAELYVQRTLLYLIRRSYAYIYSLMISSEPVSEALLPIYNQLQTLKRCLIEVKNSGGVQSVRELYPYSMKLHSIDNMRQDGKFMVNNDIPEGQGSVSELLAECFDLNYELRVAVEEQAGAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNN8</accession>
    <name>E3QNN8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">LysM domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_07795</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the secreted LysM effector family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697362">
        <property type="protein sequence ID" value="EFQ32525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096545.1">
        <property type="nucleotide sequence ID" value="XM_008098354.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNN8"/>
    <dbReference type="STRING" id="645133.E3QNN8"/>
    <dbReference type="GeneID" id="24413160"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07795"/>
    <dbReference type="eggNOG" id="KOG2806">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010591_5_0_1"/>
    <dbReference type="OrthoDB" id="5985073at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052210">
        <property type="entry name" value="LysM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997">
        <property type="entry name" value="AM15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997:SF1">
        <property type="entry name" value="PEPTIDOGLYCAN-BINDING LYSIN DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180618" evidence="5">
        <location>
            <begin position="28"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="286"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="374"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="570"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="665"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="759"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="626"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="630"/>
            <end position="648"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ32525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="813" mass="85935" checksum="5A2DFCCBC2A13B09" modified="2011-01-11" version="1">MAIATIRLRGILNSLSAVALLTLPVLADPLLKTSYLPDGISSACASALTADTACPQAIRTLQAGDYQSESRLQSLCTDDCASSLATYHSAVLSNCASDTWEGLEDEIQPVAFISEIIRYHYNFTCLSDGLRFCNNVAAAFAAAADTDAAGDPSKLPAGGDFGDHDTSDLCDSCLIKNLAFKAGSPFYDGPELQSQSIYESKTASCGITNAPLTTTANSIIPSVTEAPPTTTTCAGKTYVIQPNDDCFSISVSQSIGTEWLLQDNNLFAFCHEFPTEGNLCLVNTCDVYTVLESDTCKTITKQFGINDAQLRAWNPSINAGCYNLDKMIGAQLCVSKPGTPYVEPEPTTLAPSIPTTAAPLPTNVAVDTNDHCGKFYEVRLGDYCNLLTVKFSISLNDFRFLNPAINENCTNLYAEESYCVQAVGDINTYPGRPGATSYVLSATSGMEDSVTTMPDATWTAPTPTKTPAPLASGTLRDCASYFLGDDWQLDVTDTDYISRCQLIAEIWGVALEDLGIWNPSLGDVSAAGCTFNSGVRYCGRSHVDGNYEQPGGLTEPLFPSREGEDEDCTGWVSVGDGGTPTCQDILAKYGLTIAQFYDMNPSVGEDCSGMWAGYFYCIQTPEHQGSGGDATTAVPSGSTTASATATAGPTPPAPTLDGQPSNCNKWHVVAAGDNCGVIESEYSLTHSQFLEWNPAVSEDCLTGFWGTYAYCVGISGGGGAITTAPPATTTSAAPAEPTNGPVAVPEPNQANNAIASCNKYGQAQSGDWCSAFADRYGLAYSDFYAWNTVLGAGGENCGGSFWATYWYCIGVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNP1</accession>
    <name>E3QNP1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_07668</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697362">
        <property type="protein sequence ID" value="EFQ32398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096418.1">
        <property type="nucleotide sequence ID" value="XM_008098227.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNP1"/>
    <dbReference type="GeneID" id="24413033"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07668"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012970_2_1_1"/>
    <dbReference type="OrthoDB" id="4088837at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015343">
        <property type="term" value="F:siderophore-iron transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000197">
        <property type="entry name" value="Siderophore iron transporter 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF92">
        <property type="entry name" value="GLUTATHIONE EXCHANGER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="263"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="296"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="339"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="377"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="404"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="435"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="547"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ32398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="586" mass="63291" checksum="1D91B755FE85DDE5" modified="2011-01-11" version="1">MPTLGTKLGAASAPNTETSPLLEPEPSCNVGAPNRNDRATTSQDPFSGVAQLDAAAGKLSNTERVWLFVGIFLVGCAYGLDSQVRSAFQAYATSSLNLHSTHSTINLLRSVVAVASQPTAAKVADIYGRFETISASILFYVIGTALEASATSVELFCVGAILYQIGWTCIVLLLEVLVADFSSMRSRVFFSYMPAIPFVFNTWISGNVTAAVLRVMSWRWGIGMWAIILPVCSIPLLTSLYSFGRRSRKLEVHSESKRAAVDLFHQLDAIGLAILIAAFSFTLAPLTLAGGTASHWRSLGIIAPLAFGLSCIPTFIFWESRYAEAPLIPFRLLKDRGVWSALAVRSLLNFAWSTQGNYLFTVLVVAFDFSIETATRILSFFSFFGVFSGVLVGIVIYRTRRLKGIIIAGACIFTASFGILILYPGGATSDSQSGMIAAQIIMGVAGGLFAYPTQASIQASADREHVAVVTSLYLSIYNVGSALGNCLSGALWTQLLFPTLQHNLSFQPNSTLAQVVYNSPFSTIEHYPVGGEIRDAIIDSYKVVQRLLCIAGLCICIPMIGFAFALRDPKLSEERVQPEACIDSDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QP58</accession>
    <name>E3QP58_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mitochondrial genome maintenance protein Mgr2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_07660</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MGR2 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697363">
        <property type="protein sequence ID" value="EFQ32646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096666.1">
        <property type="nucleotide sequence ID" value="XM_008098475.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QP58"/>
    <dbReference type="STRING" id="645133.E3QP58"/>
    <dbReference type="GeneID" id="24413025"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07660"/>
    <dbReference type="eggNOG" id="KOG4096">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_142435_3_0_1"/>
    <dbReference type="OrthoDB" id="5409308at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005744">
        <property type="term" value="C:TIM23 mitochondrial import inner membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045039">
        <property type="term" value="P:protein insertion into mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018450">
        <property type="entry name" value="Romo1/Mgr2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28525">
        <property type="entry name" value="REACTIVE OXYGEN SPECIES MODULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28525:SF1">
        <property type="entry name" value="REACTIVE OXYGEN SPECIES MODULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10247">
        <property type="entry name" value="Romo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01378">
        <property type="entry name" value="Romo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ32646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="111" mass="11714" checksum="34E36A574251B5A2" modified="2011-01-11" version="1">MPPVPAQHGGAMGQSVADKLKMGAMMGGTVGAVMGFVFGSVNIMRYGAGPNGIMRTLGQYMLGSGATFGFFMSIGSVIRSDASPIANEAYRRAQRRPIIMYGPGSEYSKRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPC0</accession>
    <name>E3QPC0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Apopolysialoglycoprotein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07852</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697364">
        <property type="protein sequence ID" value="EFQ32708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008098537.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPC0"/>
    <dbReference type="STRING" id="645133.E3QPC0"/>
    <dbReference type="GeneID" id="24413217"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07852"/>
    <dbReference type="eggNOG" id="ENOG502SC93">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011402_0_0_1"/>
    <dbReference type="OrthoDB" id="275715at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="483"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="681"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="241"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="322"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="501"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="575"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="610"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="681"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="731"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="773"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="810"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="843"/>
            <end position="853"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="853" mass="88613" checksum="77B503A45A790E01" modified="2011-01-11" version="1">MAPGTRRANRSGYAEHDDFEGLPVRQWRHEWVNVEPPAPVETTQKNGIWDVELPWGMPKDVGLLPQHSQDLLRAARSGALYKRPAPVEEEETDADALTEKPEKKEDDASTKGFQIKVWKQINRNSEGSSVSHLAKRRKGTVTISSKTVSSHMPGATVTKATVRRVDAAGNPYTQEITLQEGQAVEGEIISTTVVPVAAVDPMQVAPQRVRRPPPPKKKNKPGPGRGRKKKVLPLPAPAPGAPGAVGPVDVAPVAPKVEGAEGAETPVKQDGEDSNNPDSEMADNDDDEGDDDGDEGDDDGDDEQRDGDNTDSQDQEMTDVSPAVPTPTADATTELADPESPVPKRAAPPANPISLPPLPAMHLVNSSPKGSPLKNVVVPSPTEPSLEFSLISEALAPKIEPQAESRSEPQQEDAQADVKADVPMTDGSETVTGAPTEPLNTAVPDKLPSIDTATEDAQGVSSLPPADKVGDIVSPMAETRSTFSLATTAETEASGVRLESGDQTVASNQASQDAMVLDVPEASDASNAADVPEIPEVITTSEAAPADEPPAPAVDDVTEKKAASSPAPPASAEEPPAPAPEPEPIAPIVEDMPLAPGEPAEAIKSPAKVSPKSPAASLLEPPAPIEPSVVEPADVPPEIPVEIPVETSAEMAIDAPATLPDVPVEAPVEALVDSAVETAVETAAEAPTDAPAQAPIEIPTAEPEMNQPSLVAAPVMPEDDGPDLLAGLETELDRQAEMGKSPRPEPPAAPHPEPAELPEIANPVPLPEVPAIEPEKPNDEPMLEPKEEPTGQATDAPIATTPEPGPVSAPAPTEAADPASTAEAPASTVPDDEAEKKNEQTTADAPAPAAADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQJ0</accession>
    <name>E3QQJ0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fic/DOC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_08272</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697367">
        <property type="protein sequence ID" value="EFQ33128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097148.1">
        <property type="nucleotide sequence ID" value="XM_008098957.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQJ0"/>
    <dbReference type="GeneID" id="24413637"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08272"/>
    <dbReference type="eggNOG" id="KOG3824">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053737_0_0_1"/>
    <dbReference type="OrthoDB" id="439046at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3290.10">
        <property type="entry name" value="Fido-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003812">
        <property type="entry name" value="Fido"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036597">
        <property type="entry name" value="Fido-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040198">
        <property type="entry name" value="Fido_containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13504:SF38">
        <property type="entry name" value="FIDO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13504">
        <property type="entry name" value="FIDO DOMAIN-CONTAINING PROTEIN DDB_G0283145"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02661">
        <property type="entry name" value="Fic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140931">
        <property type="entry name" value="Fic-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51459">
        <property type="entry name" value="FIDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fido" evidence="3">
        <location>
            <begin position="148"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="242"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="246"/>
            <end position="253"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ33128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="321" mass="36628" checksum="9919FF052F77D2E8" modified="2011-01-11" version="1">MSMTIRADDVYLQYSKDQDPKKLFEKASSWFSTLQNTSLNSTQTDLVLKETHDAIIRAIFGSNMIERAGLGWDITVHLCRKILAGEDVKDIPERSIEYQSELLEMYSKQSNLKGMPAQYILRGRREIIQHARAFQYIIHTFVVEQQDLTEEVIKETHRILTKGVPIVQEGFPDIPAEDYSGIYRKVHVGAGSTMFTVPQFIPAKMRELCDNLKAELEEAKERNCIDPFSIASKYSMEFVQIHPFQDGNGRTCRMILNAILCRYAGIVIPIGEQGEEREEYINIKKRASETMDGHGEYATFVLARAVTRLRGLKKKLAGKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQZ3</accession>
    <name>E3QQZ3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein arginine methyltransferase NDUFAF7</fullName>
            <ecNumber evidence="7">2.1.1.320</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_08425</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)'-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:48108"/>
            <dbReference type="Rhea" id="RHEA-COMP:10532"/>
            <dbReference type="Rhea" id="RHEA-COMP:11992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29965"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:88221"/>
            <dbReference type="EC" id="2.1.1.320"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the NDUFAF7 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.320" evidence="7"/>
    <dbReference type="EMBL" id="GG697369">
        <property type="protein sequence ID" value="EFQ33281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097301.1">
        <property type="nucleotide sequence ID" value="XM_008099110.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQZ3"/>
    <dbReference type="STRING" id="645133.E3QQZ3"/>
    <dbReference type="GeneID" id="24413790"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08425"/>
    <dbReference type="eggNOG" id="KOG2901">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024840_0_0_1"/>
    <dbReference type="OrthoDB" id="5595109at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035243">
        <property type="term" value="F:protein-arginine omega-N symmetric methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12710:FF:000004">
        <property type="entry name" value="Protein arginine methyltransferase NDUFAF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003788">
        <property type="entry name" value="NDUFAF7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038375">
        <property type="entry name" value="NDUFAF7_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049">
        <property type="entry name" value="PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049:SF7">
        <property type="entry name" value="PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02636">
        <property type="entry name" value="Methyltransf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ33281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="512" mass="55937" checksum="9BCE4A86D8FFEA83" modified="2011-01-11" version="1">MQRLFTRGALAAGLQGVAVTRAAVLPAVQQPLAVQASRGFSWTVSRHEGKKEDKEERKWSTPLAKQLAEAISMTGPVPLASYMRMCLTGDIDGYYTGLAEENRDQFGLKGDFVTSPEISQIFGELIGVWFVAEWLSQGKPKQGVELIEVGPGRGTLMDDMLRTIQNFKGLAQSIDAIYMVEASPQLREAQKNLLCGPDAPMTESKVGYHSVCKYTNLPIVWTETIKSIPQSPNKMPFIVAHEFFDALPIHVFQAVNVPHPSLPKNPTPGPPIPPKVEWREMLVSPTPPDATHATMKIPKSEQGDPIPDFQMTLSPGTTRHSRFLPESSSRYRRLKASVPDAVVEICPDASLYASDFASRIGGSKQHPKSRPTGAALILDYGTSDTVPINSLRGIRRHRRVSPFSEPGLVDLSADVDFTAIAEAATRASQGVEVHGPIEQGAFLELMGIRQRAQVLINQVRGKEEFVKAEDIAKACGRLIDRGPGGMGKVYKVMAILPENDGRRRPVGFGGDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRW5</accession>
    <name>E3QRW5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Splicing factor Cactin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_08532</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CACTIN family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697372">
        <property type="protein sequence ID" value="EFQ33603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097623.1">
        <property type="nucleotide sequence ID" value="XM_008099432.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRW5"/>
    <dbReference type="STRING" id="645133.E3QRW5"/>
    <dbReference type="GeneID" id="24413897"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08532"/>
    <dbReference type="eggNOG" id="KOG2370">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011759_3_0_1"/>
    <dbReference type="OrthoDB" id="265955at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000380">
        <property type="term" value="P:alternative mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019134">
        <property type="entry name" value="Cactin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018816">
        <property type="entry name" value="Cactin_central"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21737">
        <property type="entry name" value="POLYGLUTAMINE BINDING PROTEIN 1/MARVEL MEMBRANE-ASSOCIATING DOMAIN CONTAINING 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21737:SF4">
        <property type="entry name" value="SPLICING FACTOR CACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10312">
        <property type="entry name" value="Cactin_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09732">
        <property type="entry name" value="CactinC_cactus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01050">
        <property type="entry name" value="CactinC_cactus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Splicing factor cactin central" evidence="5">
        <location>
            <begin position="59"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Splicing factor Cactin C-terminal" evidence="4">
        <location>
            <begin position="368"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="266"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="277"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00034534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ33603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="505" mass="57972" checksum="C09C30965AE074C2" modified="2011-01-11" version="1">MDPGRRAMLSGRRSPNRRDRERDRDIASPRRDPNNRITKPSNPPPASSRPRQKDNSSYMTQDEQSRQFVADEDKFVLKQAKKKADIRVREGRAKPIDLLAFNLRFIDSDRDVFDDDDADLHVDVASPEEVLQGLDEPQLRELDSDITSYHTLEQNQRNREYWKALQTICADRRQKLKPQGPDARVVSTVSEDVDRILRPKTYEQLEALEAQIKAKLRSNDDIDVDYWEQLLGSLLVWKAKAKLRKICDAISESKATMLKLQDPEKVKALGQQQQQQPRQAGSISGPTATGNLSSDQQSRADTKTVSVPSATQGGAPPPGTARFAQVGNEDFSQATKALYDREVARGIGEDEEVFTAEEAVPSGSKPQWADKYRPRKPKYFNRVQMGYEWNKYNQTHYDHDNPPPKVVQGYKFNIFYPELIDKTKAPTFKIIREHGRKRGESFAAAGEEDTCLIRFIAGPPYEDIAFRIVDREWDYSAKRDRGFKSSFDKGILQLHFQFKKIYYRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QS51</accession>
    <name>E3QS51_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">O-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_08618</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697372">
        <property type="protein sequence ID" value="EFQ33689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097709.1">
        <property type="nucleotide sequence ID" value="XM_008099518.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QS51"/>
    <dbReference type="GeneID" id="24413983"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08618"/>
    <dbReference type="eggNOG" id="KOG3178">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005533_1_4_1"/>
    <dbReference type="OrthoDB" id="1606438at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712:SF16">
        <property type="entry name" value="O-METHYLTRANSFERASE ELCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="4">
        <location>
            <begin position="261"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ33689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="442" mass="49032" checksum="DD5C192306919651" modified="2011-01-11" version="1">MPSAAQKDELFELVSSIHTSAADITKFCDTRRLPRPSTSAPAPDLDLSHENAPYFDAKASILDAAEQLIRLIRGPREQLLALSFEHCATASLQLILKYKLANHIPLKGTTTYAAISRAVGKSEIQTALVARILEHATSYGLFNVRPGGLVAHNPTSALLVSDPDLEAWMDLSATIAYPAGASIPKALEQYGYSMEADEAAYGVSIGRKISQFQRFREADGTQLHEMFARAMRGIAAGGAYDLRHAVNGGYPWHKLDQSGHLIVDVGGGPGHVSIALAEMYRKLRFEVQDLPETVAIGEKSCPEALKSRIIYRPHDFMTPQPPHDVADNEGIAYFCRFILHDWSDKYARNILQGIASALRPEDRIIVNEVVVPEPGTESCERERRMHDRDMLMLINLNGRERTRAAFEELYSSVTPKLKVHKIHRPDQGELSLIEVIRFDSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSD2</accession>
    <name>E3QSD2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GMC oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_08903</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697373">
        <property type="protein sequence ID" value="EFQ33759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097779.1">
        <property type="nucleotide sequence ID" value="XM_008099588.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSD2"/>
    <dbReference type="STRING" id="645133.E3QSD2"/>
    <dbReference type="GeneID" id="24414268"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08903"/>
    <dbReference type="eggNOG" id="KOG1238">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002865_4_1_1"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF213">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178780" evidence="3">
        <location>
            <begin position="17"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="4">
        <location>
            <begin position="383"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="166"/>
            <end position="169"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="329"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ33759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="679" mass="72908" checksum="242D84F90E7F13C9" modified="2011-01-11" version="1">MKLLNSVAILATSASAFTSWRAPVVPQQPSAELPPNGYTYSSSGPKANSTYEYIVVGSGPGGAPLAARLALAGHSVLLIDAGEDHGADPVVQVPAVHPFSSDHVPIAWSFFVDHYANDTQARRDTKMTYLTPEGDYYVGLDPPAGSVKKGILYPRTGALGGCSQHNALVTIKPTRKDWSYIASITGDDSWAPDVMDRYFEKLEAARYLPSSVVGHGLNGWLQTRVTPVTLIAEDLKVASLVVAAATSMGKSLVGKLLGTVTGLLEILTLDINNPSPERDNAELIYQIPLSMDENYSRSSPRGFVLDVARATNKDGSKKYKLDIALNTLVTKVNFDTTGSKPKATGVDYLVGKSLYRADPRATNDDNGIPGTVFASREVIVSGGAFNTPQILKLSGVGPAEELKSFGIPVVKDLPGVGGNMQDRYEVGIVGKAPTEFALLKKCKFLNGTDPCYNDWKNNIGGPLKGSYTTNGIAFGYIKHSSVAEDEPDLFLGGVPAYFNGYFPSYSLHATQDLSIWTWLTLKARSRNNAGTVNLTSANPRDTPKITFHSLGEGIGGDKDLQAVYEGMKYGIQAFKNLIPLDGSFERIWPPAEMTSEEDLKQFARDEAWGHHASCTAPIGADDDPMAVLDSKFRVRGVDGLRVVDASIFPKIPGMYIVAAIYQASEKAADVIIEAAKTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSL2</accession>
    <name>E3QSL2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="14">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_08994</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697374">
        <property type="protein sequence ID" value="EFQ33850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097870.1">
        <property type="nucleotide sequence ID" value="XM_008099679.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QSL2"/>
    <dbReference type="GeneID" id="24414359"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08994"/>
    <dbReference type="eggNOG" id="KOG0055">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_17_2_1"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18577">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000057">
        <property type="entry name" value="ABC multidrug transporter SitT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000913">
        <property type="entry name" value="ABC multidrug transporter SitT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF11">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="57"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="214"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="292"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="767"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="814"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="883"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="913"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1000"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1032"/>
            <end position="1055"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="61"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="398"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="771"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="1118"/>
            <end position="1356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="19"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ33850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1360" mass="146326" checksum="634A3173A999C14C" modified="2011-01-11" version="1">MAALEKQEPEQAAPPVTEKPAKQEEAKEEEPKGMPFTKEFFTFFRLLFAANPTCLDYFLIIFGTIMAIAAGVPFPLLGVLFGQLVDKMNAATCAADGTSDIDAFVYESAINQKVIQMAYVGAIAFVAIYSYILSWSIISQRLAQRMRTQYVSALLRQPPSYFDKRAAAGEVSSRLHGDITAIQSGTSEKVGILICTISFFVTVFVIAFTKQPKLAGMLVSMLPAYMLSSFLGGGFIAKNTGYMTEAIEKASSIASEALSHISVVQAFGAGPRLEAKFADHMIIARKAGMKKAGVAAVQAGLLYFIAYAGNALAFWQGSIKIADSMAGRGDATVGEIYAVVYLLVDACVMLGSIAPFLPSFRGASAAYQRLQEDIEAPSEIDGTSEEGKVLPLDDPKGIVLRDVTFEYPSRPGQPVLRNVNVEFPAGKYTAVIGLSGSGKSTIAALLARLQDPNQGEILLDGHDIRELNVRSLRSFISFVQQEPSLLDRSILENIALGLINSPKPEHQRLRPFLSGGQLAELASKGKDALSSANNYGPEIQEIVDLVRHAAEQADAATFINRLDDGYGTSAGPSGSLVSGGQRQRIALARALIRDPKILVLDEATSALDSASEKRIQRAVEQAATENRTIVSIAHRLSTIRNADSIVVMEAGQVVEQGTYTELMAREDGAFARMARLQTVGTADRAPDAGSASGDSLDCSTLKGDHVVDEKSNGPEEHVATKSLKNVKFSDKESDAEEKKESDIAGLDDVKPYSTVIKGLVRLVRPSLAWLVVAIIAATIVGGTFTGAGLIFGYTVGALNPCASTAERILSMGRFFSGLMFGLASIELFANFFAWSGFGVVAEKLLYSIRVLSFRSLLDQDVQWHQSEGRTADGLLSIITKDSAAIGGFSGSTVGTVFAICVNILAGVILSHIIAWKIAVVCLVTLPILLGSGFMQLRMLARYEERHSAAFSTATSVATEAVQSIKTVAALSLESQVMDNYAQLLAPPQKQMVRASASTNIWLAISNTTGIFVNALAYWWGTQLIMKGEYTQTQFLIILMAMLISAQLWGTMFALAPEFSRARTALSRIMSVINLGKNDDLSKTGTEQKQIVGDSKTEQDIESTAEVKTKRPNAGGVKVTFNNVSFAYPSRPDINILDNVSFTLQPGQFCGLVGPSGAGKSTIMNLVQRLYFPSQGQILIDDHDIANLPSSFRDTVAVVPQDPTLFDGSVRFNVGLGSSPDTEATQAEIEEACKLANIHDVIMALPEGYNTECGPSASRLSGGQRQRLAIARALVRKPRLLLLDESTSALDAASEAALQEGLERASRGTTVLAITHRLHTVHKANVILLVEGGQIADSGTHKELMERRESYRVNAMQQMLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSY5</accession>
    <name>E3QSY5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Triose-phosphate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_09117</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homooligomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TPT transporter family. SLC35D subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697375">
        <property type="protein sequence ID" value="EFQ33973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097993.1">
        <property type="nucleotide sequence ID" value="XM_008099802.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSY5"/>
    <dbReference type="GeneID" id="24414482"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09117"/>
    <dbReference type="eggNOG" id="KOG1441">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1454276_0_0_1"/>
    <dbReference type="OrthoDB" id="6418713at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="9">
        <location>
            <begin position="59"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ33973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="186" mass="20712" checksum="4E10D0E458983B77" modified="2011-01-11" version="1">MLKAAAPVAVLLTSWIMGVATPSMKTFYNILLIMAGIVFEAVRLVMVQVPLEGDENAQQMDPLVSLYYYAPVFAVMNLFVVWASEFKTFQMQDLDRAGFPMLLLNAAFAFMLNVSSVFLIGKTSGLVMALTSILKNMFPILASTIIWHTSITFMQSFGYSIALFGLLIYSIGWDQLRALKISRTLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QT36</accession>
    <name>E3QT36_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09168</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EFQ34024.1"/>
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    </dbReference>
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    </dbReference>
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    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09168"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_150823_0_0_1"/>
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    <dbReference type="Proteomes" id="UP000008782">
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    </dbReference>
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        <location>
            <begin position="25"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="115" mass="12337" checksum="02E1F397E13CA1AE" modified="2011-01-11" version="1">MLRSANQLRLATKFPAPVAKASAVAAHLTTQSSPSMTGNTQNPTRDQTQATSAEDSAATVQKERKEKKTMAELDEELRLKLEGMSGEGGAAGVEYENGRAEGLKRGVKSNMFRVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3QT67</accession>
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        <submittedName>
            <fullName evidence="1">Exoglucanase 3</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">GLRG_09199</name>
    </gene>
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        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
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            <taxon>Hypocreomycetidae</taxon>
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            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
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    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697376">
        <property type="protein sequence ID" value="EFQ34055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008099884.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QT67"/>
    <dbReference type="STRING" id="645133.E3QT67"/>
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    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09199"/>
    <dbReference type="HOGENOM" id="CLU_2305884_0_0_1"/>
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    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.40">
        <property type="entry name" value="1, 4-beta cellobiohydrolase"/>
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    </dbReference>
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        <property type="entry name" value="Beta_cellobiohydrolase_sf"/>
    </dbReference>
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        <property type="entry name" value="Glycosyl hydrolases family 6, cellulases"/>
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    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="100" mass="10614" checksum="789656D186DC7AB2" modified="2011-01-11" version="1">MSPIASSLFSPPSLPFISVALQPDLFSLLLDPDAPEVSLELADAVVWVKPGGEFDGTNDSSTVRYGSFCGKLDAYKTSSEAGCWNQACLEMLPKNAEPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
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    <name>E3QTF6_COLGM</name>
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        <recommendedName>
            <fullName evidence="10">Endoplasmic reticulum-based factor for assembly of V-ATPase</fullName>
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            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
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    </organism>
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        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
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                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="EFQ34144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008099973.1"/>
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    <dbReference type="AlphaFoldDB" id="E3QTF6"/>
    <dbReference type="STRING" id="645133.E3QTF6"/>
    <dbReference type="GeneID" id="24414653"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09288"/>
    <dbReference type="eggNOG" id="ENOG502RXKD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048316_0_0_1"/>
    <dbReference type="OrthoDB" id="19981at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070072">
        <property type="term" value="P:vacuolar proton-transporting V-type ATPase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021013">
        <property type="entry name" value="ATPase_Vma12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31394">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 199"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31394:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 199"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11712">
        <property type="entry name" value="Vma12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="212"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="21"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="50"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ34144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="296" mass="32564" checksum="F9E135D3A956F454" modified="2011-01-11" version="1">MVQLTVTPSIADGLQRLAEVRSIRDETDTSKTGTAAQEPTSDGSATSVATPNTEEPTLNPPAVGEPITHSQVLHLWRDLKSEGIDGFSLEGLLRGANVYIPPPPPQPEPSAEYKALMAHLRREEEERTYQRMMKQSSRTDNFSQQVPGTASRAHAFAEVNRPMREADNGDDEVTLGDVQKQVMVIFNFLVSIVGVAATIWIASRWWSVTARIFLTLAGSILVLVAEVVVYSGYVWRMTEAKANREEPEEIKEVMQTWVLGEAGSGGGKSGEDATVLLDTKTPDTDERIRRRLKGMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTP9</accession>
    <name>E3QTP9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1996 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_09355</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697378">
        <property type="protein sequence ID" value="EFQ34211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098231.1">
        <property type="nucleotide sequence ID" value="XM_008100040.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTP9"/>
    <dbReference type="STRING" id="645133.E3QTP9"/>
    <dbReference type="GeneID" id="24414720"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09355"/>
    <dbReference type="eggNOG" id="ENOG502QW32">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014722_1_1_1"/>
    <dbReference type="OrthoDB" id="74764at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018535">
        <property type="entry name" value="DUF1996"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662:SF7">
        <property type="entry name" value="DUF1996 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09362">
        <property type="entry name" value="DUF1996"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1996" evidence="2">
        <location>
            <begin position="37"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="350"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="365"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ34211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="485" mass="52399" checksum="DF0642CF432547B7" modified="2011-01-11" version="1">MKYSTSSVIAAAGFFAVGVDAFWRMECRARVGLARVDPLMNFGTPATHVHAIHGSNGFSPTANYGDLVAGDCTSCAVTQDRSAYWHPALYFQDASTNEFELVDQVGGMLAYYLLNDQDIKAFPAGFRMIAGDTDRRNYTAGDPSQPDPPKSAWSTLGQTKQSDLEQRAIGFNCLNYARAPEGTLYRHALPDKAFLDANCADGVRFEMMFPSCWNGKDVDSPDHKSHMAYPDLVMTGTCPDGFETSVPNLLYEVIWDTAAYKSRNGRFVIANGDLQGFGYHADFMSGWDEDFLQSAVNTCTNLSGRIEDCPLFNIQSDDKAAQCQMKVPSVLSLENVTGPVTSLPGNVIITGDPSTEGGPAPVIPSPSSSSSAPAAPPALSYKPGKTASANPVPGEVLKAMPTSASTPVPIIQEVTPTPTSSPQPSMSFASIQTITNGNVVSVIYWEEDVVYVTMYDDITSTTTVTPTPTPVLRAKRHLHQHRHHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>E3QU51</accession>
    <name>E3QU51_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Fungal specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_09533</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697379">
        <property type="protein sequence ID" value="EFQ34389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098409.1">
        <property type="nucleotide sequence ID" value="XM_008100218.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QU51"/>
    <dbReference type="STRING" id="645133.E3QU51"/>
    <dbReference type="GeneID" id="24414898"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09533"/>
    <dbReference type="eggNOG" id="ENOG502SMKE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004083_8_0_1"/>
    <dbReference type="OrthoDB" id="424974at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF57">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="83"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="142"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="671"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="159"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="673"/>
            <end position="688"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ34389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="756" mass="82603" checksum="7F5F4B19DDC97D65" modified="2011-01-11" version="1">MSDASSPQVVDADVVSATLAPPPVTRRSSTPQAVGASPSGPSLPPTAARGQASLSGVRSKIWGGAESDAGTGNGGAGRRTERSCQLCHRRKVRCDKKQPCASCARGGFQCYYPPVGQPVRRVRKTTIADVASRISDLEKTLATGTAQRPSATFRPPQITPASTSNFISSHPVARSPEPSTTLPSGPPVKVVGDEILVRKGTSSQYFDEFLISRVIEAEHDIQSVLTTPVSEPASKAAPSPFNPMGILSAPDLKLDLVELLPPKSGSIELWRNYVDNVDHCNKVLHRPTAEVLIYTAIDDAYSAPLDSMAVIFAVFFMSAVILEPSTVQRLTGEDKMTCLHRFKTGLEQAFAKADFLEHPSVNLLQALAVYMAGLRLHNPGRGLWTLNGLAIRAAQSIGLHRDGTRLGLGPFESEIRRRLWWHLLGRDGRGGEDYGIQNPSSFSMYAGVNHPLNLEDGDLYPEMKELPPPRRGWTLVTSALIHIQCSRAWHHLAALAASWDERPTPESVRAQTLRELHEYAEGFLQQCNPVMPQQRQTILVARLIIRKLDLVTRQQWLHLEHPEARESFATEENLVEALEIIELWMSIASDELLQSYRWSLAAFPQYHMLLYLLWHMCVKPEGPSVERAWRAINMSLGIIRSVGAGISQAAKTTILDALRVKALAIRQGLAQQSGGGSEGEQEGGGGSGSVEVDGSAVRDRSLTPGATEETVEAGKPDEVTDGIDWTTAMQDLPDWSTLMNEFQVDGLDFPNFFNFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUH0</accession>
    <name>E3QUH0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_09652</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697381">
        <property type="protein sequence ID" value="EFQ34508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098528.1">
        <property type="nucleotide sequence ID" value="XM_008100337.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUH0"/>
    <dbReference type="STRING" id="645133.E3QUH0"/>
    <dbReference type="GeneID" id="24415017"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09652"/>
    <dbReference type="eggNOG" id="ENOG502REH0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038297_1_0_1"/>
    <dbReference type="OrthoDB" id="9978720at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12809">
        <property type="entry name" value="Esterase_713_like-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050228">
        <property type="entry name" value="Carboxylesterase_BioH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43194:SF4">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43194">
        <property type="entry name" value="HYDROLASE ALPHA/BETA FOLD FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179966" description="AB hydrolase-1 domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="86"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ34508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="389" mass="42820" checksum="124568BF1B1134B7" modified="2011-01-11" version="1">MHFLKLTATAALLGQAAASLPVLDFVSNLIHLNTGDSVDSEVPYVRSYFYVGGGYVDDGSGGHIFRDQMYVEKLLPVLGVTQSTPIVLIHGQAQTGSNFLNKPDGGRGWASRFVEQGYEVYIVDQTFRGRSAWMPGYGASEPSTYSAEIIQQRFTAVQKYNIWPQAVNHTQWPGTGMMGDEVFDAFYSSNLQFVNNGTYQQKTVQDAGALLLDKIGKPVVLVGHSQGGLMPIIIADARPELTKALVLLEPTGPPFQEAIFSNKSSRAYGLTDIPVAYYPEVIDPATDLVQQVYPAKGKNFVQCVLQAEEPSPRQLINLVDKPIVLVTSEASYHAPYDHCTVEFLQQAGCSKTEHLELAKIGIHGNGHMFFMEKNSDQIQKALRDWIQAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUW1</accession>
    <name>E3QUW1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Metalloprotease MEP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_09793</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Secreted metalloproteinase that allows assimilation of proteinaceous substrates.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M43B family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697382">
        <property type="protein sequence ID" value="EFQ34649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098669.1">
        <property type="nucleotide sequence ID" value="XM_008100478.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUW1"/>
    <dbReference type="STRING" id="645133.E3QUW1"/>
    <dbReference type="GeneID" id="24415158"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09793"/>
    <dbReference type="eggNOG" id="ENOG502RSGD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048726_0_0_1"/>
    <dbReference type="OrthoDB" id="536211at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008754">
        <property type="entry name" value="Peptidase_M43"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47466">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47466:SF1">
        <property type="entry name" value="METALLOPROTEASE MEP1 (AFU_ORTHOLOGUE AFUA_1G07730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05572">
        <property type="entry name" value="Peptidase_M43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3 12" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180994" evidence="10">
        <location>
            <begin position="27"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M43 pregnancy-associated plasma-A" evidence="11">
        <location>
            <begin position="161"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ34649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="219" mass="23466" checksum="46DFB997DBE391A7" modified="2011-01-11" version="1">MFDTMKFSSLLANAAAVLEMASLAMAQEKCGSEEPGAEAYQAAVSLRAVQRAEGLSAYVLAKRAKGLLIMTYLHVVEDEAHRGPASRRRPRPSAKGAYDDLNIYFETGFMKPNSVTGLCSFPVEDPWNTGINGTSWYAYDGCHVSAGTMPGGPGYPWDAGDNLGKTATHEVGHWLGLFHVFEGFDCDGEGDLIDDTPPTKVATSFRVYAFAGGANVSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QV24</accession>
    <name>E3QV24_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP synthase subunit K</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_09858</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697383">
        <property type="protein sequence ID" value="EFQ34714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098734.1">
        <property type="nucleotide sequence ID" value="XM_008100543.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QV24"/>
    <dbReference type="STRING" id="645133.E3QV24"/>
    <dbReference type="GeneID" id="24415223"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09858"/>
    <dbReference type="eggNOG" id="ENOG502SCBN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_172736_1_0_1"/>
    <dbReference type="OrthoDB" id="2094445at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015986">
        <property type="term" value="P:proton motive force-driven ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021278">
        <property type="entry name" value="ATP19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28074">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT K, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28074:SF1">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT K, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11022">
        <property type="entry name" value="ATP19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ34714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="72" mass="7594" checksum="4FD5A4EE424CEC81" modified="2011-01-11" version="1">MVQMYTIAGRQIGSHYLAMGVLATLFGGAVYGTSGSKPKATATPPINASSSDEADFIKKFLDSADKDEKAKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QV61</accession>
    <name>E3QV61_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.256</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Asparagine-linked glycosylation protein 10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">GLRG_09895</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. In the lumen of the endoplasmic reticulum, adds the third and last glucose residue from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide intermediate Glc(2)Man(9)GlcNAc(2)-PP-Dol to produce Glc(3)Man(9)GlcNAc(2)-PP-Dol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>an alpha-D-Glc-(1-&gt;3)-alpha-D-Glc-(1-&gt;3)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl beta-D-glucosyl phosphate = a alpha-D-Glc-(1-&gt;2)-alpha-D-Glc-(1-&gt;3)-alpha-D-Glc-(1-&gt;3)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:29543"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19502"/>
            <dbReference type="Rhea" id="RHEA-COMP:19512"/>
            <dbReference type="Rhea" id="RHEA-COMP:19522"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57525"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:132522"/>
            <dbReference type="ChEBI" id="CHEBI:132523"/>
            <dbReference type="EC" id="2.4.1.256"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:29544"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ALG10 glucosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.256" evidence="4"/>
    <dbReference type="EMBL" id="GG697383">
        <property type="protein sequence ID" value="EFQ34751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098771.1">
        <property type="nucleotide sequence ID" value="XM_008100580.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QV61"/>
    <dbReference type="STRING" id="645133.E3QV61"/>
    <dbReference type="GeneID" id="24415260"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09895"/>
    <dbReference type="eggNOG" id="KOG2642">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017053_0_0_1"/>
    <dbReference type="OrthoDB" id="4769at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106073">
        <property type="term" value="F:dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016900">
        <property type="entry name" value="Alg10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12989">
        <property type="entry name" value="ALPHA-1,2-GLUCOSYLTRANSFERASE ALG10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12989:SF10">
        <property type="entry name" value="DOL-P-GLC:GLC(2)MAN(9)GLCNAC(2)-PP-DOL ALPHA-1,2-GLUCOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04922">
        <property type="entry name" value="DIE2_ALG10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="320"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="358"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="460"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="691"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="395"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="567"/>
            <end position="594"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EFQ34751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="734" mass="83053" checksum="EC8F360CCD3C2A98" modified="2011-01-11" version="1">MKAVEAFVDGLNILSVVVLYTLLWLITPKMPNPDPSGPKTNKVYDVLMRVSYIIIFIFGWIWCSNVMAHVDKPYLDEVFHIPQAQKFCQGRWDEWDDKITTPPGLYILSKYYLQVMMRPECSVLDLRGVNIIAVLGVGILATHCRHLLETRRPDGQSPAPPAVLSFYSIHLGWNVALFPVLFFFSGLYYTDVVSTLSVLVAYYHHLCRVREERSSLLSDWSTIVLGCFTLIMRQTNVFWVVVYMGGLEAVAAVKALCPPPVPKANMTTLGEYIRFYTWRYSIGDVHDPPLNAAWPDDLFFSALSIGIAALANPLRILRKVYPHITIMALFAGFVYWNGGVVLGDKSNHVATLHLAQMLYIWPLFAFFSFPLFLPSAIRVLRFVRGFASALFRKAAPKPVGSGPSVPDRKHLLTNSSRSGSSKKQKTHPQESTNLAGFPFTDSLVSSPILNALQFLVQSKFYNLVLTPLLALITLAVIRFNTIIHPFTLADNRHYMFYVFRYTIRRPGLFRYYLVVPYTVARWLCWDALSGCGQGGFLSGHTEDCSGRYTTFRPGPFENNPFSSTLRARAEKPPLTEPAEETEATAPSDEKGGKGRYDPLAIVTLADPTSQSTEPPATSTAILLLLATTLSLMTAPLVEPRYFILPWVFWRILVPAWRLHEHAVTHPGLTKLEHLPGLGTLVRFGKNFDVRLILETLWFMLINAVTMYIFLAKPYMWRSEDGRVLENGRMQRFMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVQ6</accession>
    <name>E3QVQ6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_10088</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697386">
        <property type="protein sequence ID" value="EFQ34944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098964.1">
        <property type="nucleotide sequence ID" value="XM_008100773.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVQ6"/>
    <dbReference type="STRING" id="645133.E3QVQ6"/>
    <dbReference type="GeneID" id="24415453"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10088"/>
    <dbReference type="eggNOG" id="KOG0158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_11_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009403">
        <property type="term" value="P:toxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11058">
        <property type="entry name" value="CYP60B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000047">
        <property type="entry name" value="Cytochrome P450 monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF230">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="442"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ34944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="498" mass="56108" checksum="318E57AB4E8C91E0" modified="2011-01-11" version="1">MEIQFGESRLPGFVLLPLATVSLGVAGLLLWMLYNVTLHPLSKYPGPKLWAATRIPYALMVFRGDEPKTILALHKRYNADVVRVSPNELSFQHPGAWKDIMGHRSGGSEENEKDPDRLNPDNINIITAGRHDHARYRRALSHGFSAKSMQEQQPLIKDYVNLLIERLRGLAGKGPIDMVAWYNFTTFDVIGDLSFGESFGCLANSEYHPWIRSVFQNVKLVTLQNLARSFRALEPLFTMVLSKSLVEKGTAHYAFVRAKVDQRIALGTPRPDFAESMLRKGSEVSPMTKDEIYKTTGILIIAGSETTATALSGATYNLATHPKVFARLCEEVRSSFASEDEIDLLSTAKLSYLHAVIEETLRVYPPIPASLTRRTPRGGANILGQWVPGDTSVGIVQWALYHNEKYFSRPFEFHPERWLGDPAFASDSLDAFKPFHIGPRNCLGMNLAYAEMRMILARIVWTFDLRLDEGSRGWLEDQSCYTVWTKPPLMVHLTPRQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVT6</accession>
    <name>E3QVT6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Leucine Rich Repeat family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_10118</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697386">
        <property type="protein sequence ID" value="EFQ34974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098994.1">
        <property type="nucleotide sequence ID" value="XM_008100803.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVT6"/>
    <dbReference type="STRING" id="645133.E3QVT6"/>
    <dbReference type="GeneID" id="24415483"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10118"/>
    <dbReference type="eggNOG" id="ENOG502SAJ4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027499_1_0_1"/>
    <dbReference type="OrthoDB" id="1517790at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF1">
        <property type="entry name" value="RAS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52075">
        <property type="entry name" value="Outer arm dynein light chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="76"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="363"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="8"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="79"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="371"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ34974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="533" mass="59459" checksum="753DE070780D260F" modified="2011-01-11" version="1">MADEPTLPSLSPSISWDAQTERFSNNPRKRRYNFKSHSVAPPSWSNSSDPAVFSSDDDPGLDNYVEGRRKKKKYVGSWFHQQPASSDSATGEPRPALRGKRTLKRDLDSGVWMGSDSTDGEESIMMPDLPTQSRLPQLNLAPPRRRNVVSAQELEARERIQQCLDSGNEYIDLSMMELKTLSDATIRPLSEFSCIPIVAEGVPFEQKDPALQLYLYRNPLIKLPGAIFDLEHLTVLSLRGCRLRELPPAIGKMRRLRTLNLAQNLLRYLPAELLDLMAAPSALEELLLQGNHFFQATERPRLGGLENLEGNGSEGLELVGAWKPGTDGVAARFFARSPVHYLDSLGLSHSDFRLDPEAVIVRTERQDGKRSTSSGSPTSSAPYHSKSAGRCVASVKGSRVPSLVELALRSAYKSSDLDELPHYIPDSLSHLQTLLERAADQREAGGLTCAMCKKPFVAPTTQWLEWWQVCLVESRQNEEGYAVKARPWTDLDEENDGAVPFLRRGCSWKCGPAHVREGQWTIRATPKSLQEQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWY8</accession>
    <name>E3QWY8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_10520</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697392">
        <property type="protein sequence ID" value="EFQ35376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099396.1">
        <property type="nucleotide sequence ID" value="XM_008101205.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWY8"/>
    <dbReference type="GeneID" id="24415885"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10520"/>
    <dbReference type="HOGENOM" id="CLU_2757633_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ35376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="70" mass="7578" checksum="A56BE2B42D48D924" modified="2011-01-11" version="1">MPRPSLARTINKGDGISSQSYYSSPYYAQGDGFVSLSMGTLGTRDINATYCISACLQMSARIRPPVAVRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>E3QX93</accession>
    <name>E3QX93_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">Vacuolar protein sorting-associated protein 27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">GLRG_10625</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 12">Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 12">Component of the ESCRT-0 complex composed of HSE1 and VPS27.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 12">Endosome membrane</location>
            <topology evidence="2 12">Peripheral membrane protein</topology>
            <orientation evidence="2 12">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the VPS27 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697394">
        <property type="protein sequence ID" value="EFQ35481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099501.1">
        <property type="nucleotide sequence ID" value="XM_008101310.1"/>
    </dbReference>
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    <dbReference type="STRING" id="645133.E3QX93"/>
    <dbReference type="GeneID" id="24415990"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10625"/>
    <dbReference type="eggNOG" id="KOG1818">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011862_1_0_1"/>
    <dbReference type="OrthoDB" id="957735at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033565">
        <property type="term" value="C:ESCRT-0 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15735">
        <property type="entry name" value="FYVE_spVPS27p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21385">
        <property type="entry name" value="GAT_Vps27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16979">
        <property type="entry name" value="VHS_Vps27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.1940:FF:000001">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.90:FF:000031">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000161">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017073">
        <property type="entry name" value="HGS/VPS27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002014">
        <property type="entry name" value="VHS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049425">
        <property type="entry name" value="Vps27_GAT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47794">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47794:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02809">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00790">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21356">
        <property type="entry name" value="Vps27_GAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036956">
        <property type="entry name" value="Hrs_Vps27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00726">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00288">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50179">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0967">Endosome</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="VHS" evidence="16">
        <location>
            <begin position="26"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="FYVE-type" evidence="15">
        <location>
            <begin position="168"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="230"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="292"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
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            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="462"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="346"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="482"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="557"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="603"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="621"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="678"/>
            <end position="698"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR036956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EFQ35481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="710" mass="77768" checksum="728C3E25D95C1693" modified="2011-01-11" version="1">MMGWWSSSANTALDEQIEKATSSSLEDIALNLEISDVIRSKTVQPKEAMRSLKRRIGNKNPNTQLSALNLTDTCVKNGGTHFLAEIASREFMDNLTSLLQAVGPAAVNHEVKQKILELIQSWAAATEGRHDLGYIGEVYKTLQREGHQFPPRVSVASSMIDSSAPPEWVDSDVCMRCRTPFTFTNRKHHCRNCGNCFDQQCSAKTCPLPHLGIMQPVRVDDGCYAKLTDKSSKAGAPSPLPQDRSPTYPYKTRSTSAMQPRNARVDDAFDEDLKKALAMSLEEVKGYSQGYVAPTANGPSGPKVNGNSKPAASHGADEDDDDLKAAIAASLADMEEQKQRHATALKEQTSSAGPNPTQQFSLPRNDYELTPVEAENINLFATLVDRLQTQPPGTILREPQIQELYDSIGTLRPKLARTYGETMSKHDTLLDLHAKLSTVVRYYDRMLEERLSKAYSQHTVGGYNLPTPRGPSGAYPSLHASAPSSTGPAENFYTGSQQVNYGRVPPQEYHQHPQHTPQPQYATYDKRASMAGPPTGSYPPQEPQQTDSWRSGAGSAPNGQYTPQQPYAPSEPPQPGHQSHPVQPAGTPSADPSASYYFNPQQPSAPPSAPPAVDPNPSPYPNLQQSMQYRQSMSQQATPVQAAAQPAQQQGPPQQQSYWQPSVPQQSAPPQQQWQGQYNDNNNGYTQESFPSAPQNAPKQPAVEESLIDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>E3QX96</accession>
    <name>E3QX96_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Elongation factor 1 alpha-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">GLRG_10628</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the Dom34-Hbs1 complex, also named Pelota-HBS1L complex, composed of dom34 and hbs1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697394">
        <property type="protein sequence ID" value="EFQ35484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099504.1">
        <property type="nucleotide sequence ID" value="XM_008101313.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QX96"/>
    <dbReference type="STRING" id="645133.E3QX96"/>
    <dbReference type="GeneID" id="24415993"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10628"/>
    <dbReference type="eggNOG" id="KOG0458">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007265_3_2_1"/>
    <dbReference type="OrthoDB" id="342024at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990533">
        <property type="term" value="C:Dom34-Hbs1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002184">
        <property type="term" value="P:cytoplasmic translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01883">
        <property type="entry name" value="EF1_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16267">
        <property type="entry name" value="HBS1-like_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000020">
        <property type="entry name" value="Translation elongation factor EF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000070">
        <property type="entry name" value="Translation elongation factor EF-1 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000204">
        <property type="entry name" value="Translation elongation factor Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015033">
        <property type="entry name" value="HBS1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050100">
        <property type="entry name" value="TRAFAC_GTPase_members"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004160">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23115">
        <property type="entry name" value="TRANSLATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03143">
        <property type="entry name" value="GTP_EFTU_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08938">
        <property type="entry name" value="HBS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 15" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="Tr-type G" evidence="14">
        <location>
            <begin position="399"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="164"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="188"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="235"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00063537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00074866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EFQ35484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="808" mass="87495" checksum="C2D97A62896DB377" modified="2011-01-11" version="1">MSRHQAVRNLDYEEALDEYEGEEDFEENEADQLSPEDREAMNVGTATVQSALGPDGDKVTVQQIQDALWYYYYDIDKTVSYLQKKLIAPPPAPKQEPKKAKDDGFGLGGINGEIANYDDTASTSEYPIRRVASLSPASSFHGISWTNVPSNRKAVFVPPRPLPGGVLGGGEGPKISKLQALAAARKKKTEDAKKPDDKVDRAEKRMSTLALDETSKQTQRSGSIILAKRQKLAEGSTSGSRASTPVSQPQQDKAAPNPVGMDVDQSRASSAGYGEDAEDDCLVVSSKRPSAFAQTLFGPAHNAAAASQIYTLPYMDSSTFVPSAFSQPSPDDIVLAAQAKAGTKFDAAAAKSATKKVVSKPTGSQTPTGEMKQLQLDDSAAPKNKKLDVLKEFEKSENKRSASFVVVGHVDAGKSTLMGRLLLELKYIEQHLIDRYRRQGEKIGKSSFALAWVMDQREEERERGVTIDIATNQFETDKTRFTILDAPGHRDFVPNMIAGASQADFAILVIDANTGAFERGLKGQTREHALLLRSLGVQRVIVAVNKLDMVGWSKDRFDEIAEQVTGFMKGNGFQLKNVTFVPISGLSGANLVQRPDDEGLSWYKGPTLIEALEDSDPMTRALEKLFRMSISEIYRTQQSQLTVAGRIESGTVQNGESLIVQPSGEAASIRSIEVDGEVQDWAVAGQNVNIGLYGIDPIHVRVGDIISTKAAPIETSDTLTMKVLAFDHLMPMPVDVHRGRLHAAGRVGAIPAVLDKLTGATVKKNPKIVQPGKVARVVVKLESKVPLEAGQRVVLRSGGETIAAGLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXE2</accession>
    <name>E3QXE2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10674</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697395">
        <property type="protein sequence ID" value="EFQ35530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099550.1">
        <property type="nucleotide sequence ID" value="XM_008101359.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXE2"/>
    <dbReference type="STRING" id="645133.E3QXE2"/>
    <dbReference type="GeneID" id="24416039"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10674"/>
    <dbReference type="eggNOG" id="ENOG502S8NQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046006_6_1_1"/>
    <dbReference type="OrthoDB" id="10249419at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07262">
        <property type="entry name" value="VOC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35006">
        <property type="entry name" value="GLYOXALASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G14830)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35006:SF2">
        <property type="entry name" value="GLYOXALASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G14830)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="2"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="129" mass="14253" checksum="41B716BAC3EE2D40" modified="2011-01-11" version="1">MSIDHVGLFVPASIYKETVDWYLTVLAPVGFQKFVEPNEYACGLGVHRPDFWIASHNADKANIPLHLGFKAENRKAVDEFHKAAMAAGAKDNGAPGLRPQYHPNYYGAFVIDPSGNNIEVVCHMPEVTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXS6</accession>
    <name>E3QXS6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nonselective cation channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_10771</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697397">
        <property type="protein sequence ID" value="EFQ35627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099647.1">
        <property type="nucleotide sequence ID" value="XM_008101456.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXS6"/>
    <dbReference type="STRING" id="645133.E3QXS6"/>
    <dbReference type="GeneID" id="24416136"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10771"/>
    <dbReference type="eggNOG" id="ENOG502QT9R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009570_2_0_1"/>
    <dbReference type="OrthoDB" id="2373987at2759"/>
    <dbReference type="PHI-base" id="PHI:9110"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056337">
        <property type="entry name" value="LHD_YVC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052971">
        <property type="entry name" value="TRP_calcium_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056336">
        <property type="entry name" value="YVC1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35859">
        <property type="entry name" value="NONSELECTIVE CATION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35859:SF1">
        <property type="entry name" value="NONSELECTIVE CATION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23190">
        <property type="entry name" value="LHD_TRPY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23317">
        <property type="entry name" value="YVC1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="283"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="308"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="342"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="375"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="415"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="481"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="domain" description="YVC1 N-terminal linker helical" evidence="3">
        <location>
            <begin position="67"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="Calcium channel YVC1-like C-terminal transmembrane" evidence="4">
        <location>
            <begin position="289"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ35627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="707" mass="79667" checksum="C9F05B88B7EC68FB" modified="2011-01-11" version="1">MEEAECPRTPDLIDWSRPLSPWADENPATRTGDANGGMDPDLEADRHVSASATGTVSTEVPPSVYFTIHRIRRLVLASIDDPYTLDQLREPRMNLLVVRPLVDRLYDPDDPAVVYCLFANRIQFLRQHTSTARQTVNVARATLCELVASRVLRRYHEDHPGQIGLLILAHILVEGFDPFQGAPEEVESECRQLQWPIQRRDGHERKLTTLELAIISESKLFLSSSACQRLVDAVWNGVVTYTPLSFVDILPDHYEYASVSLYEPHQAPLLDVGRLLVPWIRQMIELFQFITLVILYILTMVNRSSPTLSGWECVFAIYTAGWTLNEFAAIIEHGWVVHSQTLWSFLDITFSLIFSCYIFARIYDTMGYQGVVADGYGVHILCVAAPVLLTRLAFTLLPDNIVFIAMHAMMKDFTRLTFISIWCFMGFFLALHWLVGSNDDTSAVAGGKAALTWYETCKWLIWTWFGLDGTGIDRSDEFHPILGPALMIAFAFLGNILFLTILVAILSNTFSKLISDAPAEIQFRRAVLTFAGVKSDSIFSYPPPFNLLALAALLPLKSMLSPRSFHDVNTSLIRALNAPALMIISALERRRVAHPRRARSQSLLNWSFSGFNPHGDIQAVFKVEPPPAVERELEELDNLSDVGFAESELGDREPWDVGRSMPRRRPVRRRRPARMGSPISIVFPLPSVQRAGTNEFEPLSGSPVRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXY5</accession>
    <name>E3QXY5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10878</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697398">
        <property type="protein sequence ID" value="EFQ35723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099743.1">
        <property type="nucleotide sequence ID" value="XM_008101552.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXY5"/>
    <dbReference type="STRING" id="645133.E3QXY5"/>
    <dbReference type="GeneID" id="24416243"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10878"/>
    <dbReference type="HOGENOM" id="CLU_2644615_0_0_1"/>
    <dbReference type="OrthoDB" id="5279542at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="77" mass="8532" checksum="7160CA33D35CDD9D" modified="2011-01-11" version="1" fragment="single">MPRKPQDDIPDGLEGYVPHENHGDRKANLYSRPWHIAKIAIRGCDIAFSTIVIGITLNKLVTIGYSGPYLLLFSGIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QY63</accession>
    <name>E3QY63_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="16 18">Delta(24(24(1)))-sterol reductase</fullName>
            <ecNumber evidence="16 18">1.3.1.71</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">C-24(28) sterol reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="18">Sterol Delta(24(28))-reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">GLRG_10996</name>
    </gene>
    <organism evidence="20">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>ergosterol + NADP(+) = ergosta-5,7,22,24(28)-tetraen-3beta-ol + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16933"/>
            <dbReference type="ChEBI" id="CHEBI:18249"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.3.1.71"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="17">
            <dbReference type="Rhea" id="RHEA:18503"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="15 18">Steroid metabolism; ergosterol biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 18">Belongs to the ERG4/ERG24 family.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.71" evidence="16 18"/>
    <dbReference type="EMBL" id="GG697400">
        <property type="protein sequence ID" value="EFQ35801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008101630.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QY63"/>
    <dbReference type="STRING" id="645133.E3QY63"/>
    <dbReference type="GeneID" id="24416361"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10996"/>
    <dbReference type="eggNOG" id="KOG1435">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015631_3_1_1"/>
    <dbReference type="OrthoDB" id="5326588at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="F:Delta24(24-1) sterol reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="C-24(28) sterol reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001171">
        <property type="entry name" value="ERG24_DHCR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018083">
        <property type="entry name" value="Sterol_reductase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21257">
        <property type="entry name" value="DELTA(14)-STEROL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21257:SF31">
        <property type="entry name" value="DELTA(24(24(1)))-STEROL REDUCTASE ERG4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01222">
        <property type="entry name" value="ERG4_ERG24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01017">
        <property type="entry name" value="STEROL_REDUCT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01018">
        <property type="entry name" value="STEROL_REDUCT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3 18" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11 18" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="9 18" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 18" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="14 18" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="10 18" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="13 18" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="4 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 18" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="140"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="296"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="332"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00029435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00038892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00048918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU369120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EFQ35801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="475" mass="55050" checksum="01D72D8AF67B6CD1" modified="2011-01-11" version="1">MSAKRGNTVVSATSVRSKTDVIDTPALSLSTKYKDGASDEFEFGGSLGTLALMIGFPLVMWYMWIGATYYDGQIPLPEPNQSWPEFGHHLARLVYEGAYPTAKAWGVYWVFFVGEALMYCYMPGVSSYGRPLRHEGGRRLPYYCSAYASFYATLAIAALLHVTRVFPLYTLIDEFGSFMTVAILSGFINSFIVYFQALARGRTHRLTGFPIYDFFMGAELNPRVGILDFKMFYEVRIPWFILFLITCSVAARQYERYGYVSGEVMFLAAAHFLYANACAKAEQMIITSWDMYFEKLGFLLTFWNMAGVPFTYCHCALYLANHDPSEYHRSPYALAALTAAYLFFYWMWDSANGQKNAFRHQERGQLIKRNTFPQVPWQAIEDPKVIETDTGDRIMVDGWFAIVRKPNYVPDMFFSFSWGLITGFKSPFPWFYFVFFMVMIIHRTDRDISRCRRKYGEAWKRYEREVPYLFIPYII</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYA2</accession>
    <name>E3QYA2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_10949</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697401">
        <property type="protein sequence ID" value="EFQ35840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099860.1">
        <property type="nucleotide sequence ID" value="XM_008101669.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYA2"/>
    <dbReference type="STRING" id="645133.E3QYA2"/>
    <dbReference type="GeneID" id="24416314"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10949"/>
    <dbReference type="eggNOG" id="KOG1201">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_8_2_1"/>
    <dbReference type="OrthoDB" id="1933717at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901:SF1">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ35840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="288" mass="29975" checksum="B9373F96289D2178" modified="2011-01-11" version="1">MQPPLPSVTPTWRNDTYDAISPSRPELSAAGKTIIVVGAGSGIGRETALAFATAGASRVILLGRTEAAVAQTAASLPTSVQGDVHAVDITNEEALTKVAAAAGQWDVLVLTAGYVSSPSPVAASSSDEWWQSFETNTKGTYLVTKAFLPTANPSHAAVVALTTGTTALPAVALPGLSAYMASKLAQTKIIEFLAAENPNLFAVTLHPGMVETDIFKKSGAKAEALPMDKVQLPAHFTVWLTSPEAAFLSGRTVWANWDVEELKQSAGAIQSGQLLTSGINGWPYTSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYB6</accession>
    <name>E3QYB6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Zn-finger in ubiquitin-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_10963</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697401">
        <property type="protein sequence ID" value="EFQ35854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099874.1">
        <property type="nucleotide sequence ID" value="XM_008101683.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYB6"/>
    <dbReference type="STRING" id="645133.E3QYB6"/>
    <dbReference type="GeneID" id="24416328"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10963"/>
    <dbReference type="eggNOG" id="KOG0804">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009969_0_0_1"/>
    <dbReference type="OrthoDB" id="273556at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
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        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
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        <property type="entry name" value="BRCA1-ASSOCIATED PROTEIN"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF02148">
        <property type="entry name" value="zf-UBP"/>
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    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
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    </dbReference>
    <dbReference type="SMART" id="SM00290">
        <property type="entry name" value="ZnF_UBP"/>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50271">
        <property type="entry name" value="ZF_UBP"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="379"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="UBP-type" evidence="8">
        <location>
            <begin position="415"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="61"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="338"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="695"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="579"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="63"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="87"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="112"/>
            <end position="121"/>
        </location>
    </feature>
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        <location>
            <begin position="338"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
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            <begin position="353"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="702"/>
            <end position="712"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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            <dbReference type="PROSITE" id="PS50271"/>
        </source>
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        <source>
            <dbReference type="EMBL" id="EFQ35854.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="723" mass="80266" checksum="EAF228D0F55B3E12" modified="2011-01-11" version="1">MRSFFYHLKFELYPTSSPATGDATKTKGKAQAAAVFDKDLWLPPKGADIFAELPVHSKKKSRQANLSYRPQPSPLQSFESPYPADTYRSSTLRAPTESPSPNLIDCGPSRALVKEDSGSNIERLSERQWRARTQSFPPPPSSAALRPEAAVRDWRFGRVSIESIDVDLESDAHTNQMATEAASSAADLGVGPTFGGTGKSTKAKYVPLETKNTEVGWGVVHFYREEEDTPGLGLPPSEDEGVEAEECTTLCIPAVPSYLSPGDFLGYVGEKWRDDISHYRMVMTARMNRYLVLLKFRNSKRAREWQKEFNGKVFNSMEAQVCHVVFVKSITFETPTRENRTFPDLNHDPFTPSSSSVAASSSLKPFPPPTPSLVELPTCPVCLERMDDTTGLMTIPCQHVFHCTCLQNWKGSGCPVCRHTNPETAYDPSNPYTQPFGSSVSNLCSVCDSTDDLWICLICGNVGCGRYKGGHAKDHWKETAHSFALELETQHVWDYAGDTWVHRLIRDKGDGKVVELPGSNGHHHSPEGGYEDTVPRAKLDNIGLEYTHLLTSQLESQRVYFEEMLSKVADKASKAAATAESASTQAAAALEENATLKAELTRLRTQVIPQLERDAERDRNKATKAQELARNMGKALQEEKQVTQGLMKRVEHNNAEVEALRKKDEEYKAQIAELEEMNRDLSMFISGQEKLKELESEGKVGAGEVAEGSVSVPERKGKRRAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYC8</accession>
    <name>E3QYC8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_11057</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EFQ35866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008101695.1"/>
    </dbReference>
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    <dbReference type="eggNOG" id="ENOG502SY9C">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="4839435at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37048">
        <property type="entry name" value="QUESTIONABLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37048:SF2">
        <property type="entry name" value="QUESTIONABLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ35866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="291" mass="32866" checksum="B21391F0939B7CC5" modified="2011-01-11" version="1">MDNEMMTTSAAMAARRINNSLSGKIMWLPSRNSIPSNLLEPVLENGAYNHPVVIMSNNPSPEGLVEVFLITSFGTRSIDEAFDHKWKHWLHYTPIEPAVHPEVEPLRLIEGSQRLEKQSYVNSRQAHMVQLAALRPHRGSGPGADSIIEQASLKSLKLTSHFIDLFNPRTPKRLRDYKMWEMDHKWRKGEDQAQPLPSGSVVTNPYFPAFSWLAAETPSSQATISQATSTPIYNAPTYNAPTYNAPTYNTHTYDTQAYSGYHQTVSNWRATQHQHRDISSLASWRPSTSAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYH0</accession>
    <name>E3QYH0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_11016</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697403">
        <property type="protein sequence ID" value="EFQ35908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099928.1">
        <property type="nucleotide sequence ID" value="XM_008101737.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYH0"/>
    <dbReference type="GeneID" id="24416381"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11016"/>
    <dbReference type="HOGENOM" id="CLU_517783_0_0_1"/>
    <dbReference type="OrthoDB" id="10498197at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="180"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ35908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="526" mass="58845" checksum="53BCD13DB49883C8" modified="2011-01-11" version="1">MPSSSRREDRERENKTYRLLQAKVRAEAEADAKRHAAAGAQQRGPAPDEAKQRRVRFSDTPETFWYTESTPEGQGSEDGGNRDYEETAISQEPYEDHHHHHQHQQQQQHPAGGHRGEKPEKYSFRDAILVASGATLNWTTSHHQDCRVAGSLESAHPGHGSNNKNNKRGRLGFLLRLLRFFIRHYCVVLAVLLGIISWVVLAWFCDVVQTRIRSVADLLSSPLALPQAALSGLMGAAWGILSPSAHDAGPWNPSSSTAAADFSPIVPDLSTVLGVVYRTESGVNALSEMTTNVQRDTQLNSAMNFLFTMYEATDLHWIAHLREEELGLSHLTLQLQDFAERAGRKRRVPLPWVLCRVPLVSGLETCRASADRFDVQMQTVLDFLSEAKEYRNSVYNNHMTAPAMHKVSRLVCRLGDSFGRVSLGLRETVPDADVAGSPLMDAHVLDTYLQDQQDGLRMSCHVIVDIGSEMADKRKQMDDDIKMLTRMTRSIGHIRLSVADNTLQVNRACKAVIKDLGMLTERLNSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZ32</accession>
    <name>E3QZ32_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11264</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697409">
        <property type="protein sequence ID" value="EFQ36120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100140.1">
        <property type="nucleotide sequence ID" value="XM_008101949.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZ32"/>
    <dbReference type="STRING" id="645133.E3QZ32"/>
    <dbReference type="GeneID" id="24416629"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11264"/>
    <dbReference type="eggNOG" id="ENOG502T4C8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_580027_0_0_1"/>
    <dbReference type="OrthoDB" id="4590776at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="392"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="145"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="471" mass="51243" checksum="44DF90EC37FFCE0A" modified="2011-01-11" version="1">MAPQQNTFAVIPAAPGRVGGAPSKPPMTSKQAQKLYKQANKEPRRSKAEQRRWEKERQEDIRKELEKERAAAKARAARERKKAKEEEARKSRRRAGQPLFDCRPSQDTIARFVRGNGTSRKRDSSGEPVPKDEDTPASSLENKPKLSLAPSAARAASSVSCPPPTPPERPKPLAISMAPPPGASQKSRTVNKPPQSLPNPPNQPPSWDIPPPPMQHSKDGPAVLPSSLLKVVDSSNHVPDKTLAVPVSMDPPLRPPLKSKSKPFMMPRVSLPVQQPSGREVFKPNPTSKSTPISPLSGPLLQHKLSLPDPASQGEPPQMPTPQVPSQKPPPQSTVPTPLLKSLSKDSTSQKLSVQTPPLSRPQPQAPPPSTQAIVQDCFDDFFPTASQLAMELEQDSDSDTQPGEVLDQQSNDPLAAKVGHGELVDLMMSSQEVLDIESTTKNTTQSFSSQSPFLEMDLAAIDWDDDLDDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZ44</accession>
    <name>E3QZ44_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11276</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697410">
        <property type="protein sequence ID" value="EFQ36132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100152.1">
        <property type="nucleotide sequence ID" value="XM_008101961.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZ44"/>
    <dbReference type="STRING" id="645133.E3QZ44"/>
    <dbReference type="GeneID" id="24416641"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11276"/>
    <dbReference type="eggNOG" id="ENOG502SCE0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033666_13_3_1"/>
    <dbReference type="OrthoDB" id="5151590at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038717">
        <property type="entry name" value="Tc1-like_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13358">
        <property type="entry name" value="DDE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tc1-like transposase DDE" evidence="1">
        <location>
            <begin position="22"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="81" mass="9531" checksum="2C07C4D5FCCB9C4A" modified="2011-01-11" version="1" fragment="single">RSELIFLTRDKNSRQGGYTTNRYIQTLDEGFLPVYDDFRHFVQDNAPIHTSAQTLSWLRSHGVSWLDWPPYSPDLNPIKHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZN1</accession>
    <name>E3QZN1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NAD dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_11464</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697418">
        <property type="protein sequence ID" value="EFQ36319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100339.1">
        <property type="nucleotide sequence ID" value="XM_008102148.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZN1"/>
    <dbReference type="STRING" id="645133.E3QZN1"/>
    <dbReference type="GeneID" id="24416828"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11464"/>
    <dbReference type="eggNOG" id="KOG2774">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_19_0_1"/>
    <dbReference type="OrthoDB" id="16464at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050005">
        <property type="entry name" value="DenD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF043036">
        <property type="entry name" value="ErythonDh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43103:SF3">
        <property type="entry name" value="ADP-L-GLYCERO-D-MANNO-HEPTOSE-6-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43103">
        <property type="entry name" value="NUCLEOSIDE-DIPHOSPHATE-SUGAR EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="3">
        <location>
            <begin position="5"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ36319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="319" mass="33916" checksum="169A8DC005DE8B0E" modified="2011-01-11" version="1">MSNEILVTGAAGFVGQALVSALIKANPATTLTITDVVEPPIPIDVTEASSRINSLKADLTDSQAVSSLLSKQFGAVYLLHGLMSGGTEANLDLGLKVNLDSVRNVLDYLRENYPGTTVVFTSSCAVYGPRQPVIESETVPKPKTSYGTEKLIVELLLEDYSRRGLIDGRIVRLPTVTVRPGAPSAAASSFASGIVRESLKGIKNILPVSRDLEVWVCSPATVVKNLIKIKDVPKEKFGDSRVVNLPGITVTVQEILDAVEKVGGKEALAQVEEKSDPKISAIVSTWAARFDVSRAYGLGLEPDGSILDAVEAFAKTLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZQ8</accession>
    <name>E3QZQ8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_11491</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="GG697419">
        <property type="protein sequence ID" value="EFQ36346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100366.1">
        <property type="nucleotide sequence ID" value="XM_008102175.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZQ8"/>
    <dbReference type="GeneID" id="24416855"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11491"/>
    <dbReference type="eggNOG" id="ENOG502SPC3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093250_0_0_1"/>
    <dbReference type="OrthoDB" id="5426355at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="9" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="12">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="200"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ36346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="218" mass="22900" checksum="B02013D4BD51B44A" modified="2011-01-11" version="1">MSGLSTTIMPFAQLPACAQQCGPLFDANGACVPPAVPAADAKVYDACFCSQPALQPFKTAATGVCDPAGCDAAGFSSIQGWYTSFCNSVAGGAAVQTSSSPGSTSTASKGSSNGNGGDWLSNHWRWVVMLVILVVAIAGIWVGACIWRRRYLRRKDRMYELGKHAHQGPSGIIAGSGVNVNQAGIVNAPGQFMPGPHPAIYDEKPPKEKKKWVVNERT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3R077</accession>
    <name>E3R077_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_11661</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697432">
        <property type="protein sequence ID" value="EFQ36515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100535.1">
        <property type="nucleotide sequence ID" value="XM_008102344.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R077"/>
    <dbReference type="STRING" id="645133.E3R077"/>
    <dbReference type="GeneID" id="24417025"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11661"/>
    <dbReference type="HOGENOM" id="CLU_2454607_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ36515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="89" mass="9570" checksum="CFB6DFC757920738" modified="2011-01-11" version="1">MMCGELEDDGHGTQIYTTFAHPFGIISTAIGNCKYLLACIEEDLRMYSYSSQPHTRIVPAVGAIFDGKLLTKGTSISVTHCATSNSPAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3R091</accession>
    <name>E3R091_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_11688</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697435">
        <property type="protein sequence ID" value="EFQ36529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100549.1">
        <property type="nucleotide sequence ID" value="XM_008102358.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R091"/>
    <dbReference type="GeneID" id="24417052"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11688"/>
    <dbReference type="HOGENOM" id="CLU_449766_0_0_1"/>
    <dbReference type="OrthoDB" id="10660335at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="150"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ36529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="571" mass="64042" checksum="B05B8DE16E0CF03A" modified="2011-01-11" version="1">MDPVGQDRNSTPETADSPHILDQYEIDQDGKDQDEARQKTLCFTVRFRRPWSGAPSPHASTQCFSQQGISITFQDTYMLEDISPLSIKLRDSHHLDFGHALFDPTENPDHEIFVIESAIDLFRPPDSSPHVLWSWRQCPALIWSSSRSRCLVVVGLLALLLLLVIVGAVLASHLRISSYLSRPLERSPQSNQRVHVQHAALTLVDDITQILHLYVETPLPFFVGVQDLVDRHYLIDGNTPRPPTRATPSPDSNITARVFLGHVFYSINQLCDTVQDWMALSRPAPPGKEDLALLCLGLRRAVADLSPLWSEASTTLALSWLSSFELVSFYFQEAVKAVLLPLDINVDPATTPTTCFYNYTSNTFIRQIYTHLFSSSPIVMSIYEAAEQLVELSDALLAVITSGSLLVDILSKGDVITRSRHIRTDAPRGWFAASPPRSRTDQALSLIAPAYDEVAPLLRTAVSATWAVSATRERLQGLVEAFEGLGNRTRALCSAPVPVACGDDNSEWWRGLPWVSETAGDDGRLIRTFWYLPRAKEWPSLLSWGCAKLRQTQMEWKWAVLETERYWHGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0A9</accession>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11682</name>
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    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EFQ36547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100567.1">
        <property type="nucleotide sequence ID" value="XM_008102376.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0A9"/>
    <dbReference type="GeneID" id="24417046"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11682"/>
    <dbReference type="HOGENOM" id="CLU_2061331_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180101" evidence="1">
        <location>
            <begin position="20"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="119" mass="12726" checksum="8FEFA88CBD42E130" modified="2011-01-11" version="1">MWAVIGIYAVAIFVHVVKISEVTDAFEQLIQATCCLGQENLSDKFAAQVNGGRNRVDGSPTNSAFSAEYIALGMASSTINHLSWPPPLSLACSVPAGLHDVLGKVNVPERQPGHRPGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0H0</accession>
    <name>E3R0H0_COLGM</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
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    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_11753</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697445">
        <property type="protein sequence ID" value="EFQ36608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100628.1">
        <property type="nucleotide sequence ID" value="XM_008102437.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0H0"/>
    <dbReference type="GeneID" id="24417117"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11753"/>
    <dbReference type="HOGENOM" id="CLU_043553_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
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        <location>
            <begin position="65"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="221"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ36608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="373" mass="42155" checksum="870064285FD24F62" modified="2011-01-11" version="1" fragment="single">ILDDTARCTFESAESLATASGFSLYFQHNVLNNESVEKYRKAISISQTEDLGQLYADMRNVKRLYGGGGKVHEPRGRRHGSPPTRDRRSSPASATTASCGSTLPFETVPRDEQESPPPYDCLSEGQSPGVSSDAAAAGILAKSPRAGLAPPDYCDTERWHDVLGPFQRGCCGSEDTDMHLIASAKRKRPLTAFRQEKVWRSLLGDKSHVGNLELQSRDIELQRQDIELQRQQIEVQHQEIKLQRQQIELQRQQIELQRQEIGQLQNNVEELRRQVKSLEERDEALEEDCSNLKERGDQTDIDIDDLSTDILNLGDKCEEAVEKIADVREEFEGLKGAMEGKCGSFMDRVTEDMEERVVAHMNEMKERLRQALQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0R7</accession>
    <name>E3R0R7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_11854</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697478">
        <property type="protein sequence ID" value="EFQ36705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100725.1">
        <property type="nucleotide sequence ID" value="XM_008102534.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0R7"/>
    <dbReference type="STRING" id="645133.E3R0R7"/>
    <dbReference type="GeneID" id="24417217"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11854"/>
    <dbReference type="eggNOG" id="ENOG502R1DC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022195_1_0_1"/>
    <dbReference type="OrthoDB" id="4796384at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="299"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ36705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="521" mass="59372" checksum="3FAC7B2EFE229A00" modified="2011-01-11" version="1">MDTSTISLHLHLPPQLVKLLSSTPALSVAILLAFVLSFVLNRAIEDRSIPKITSSKSWLAARQDFNAHGVKIIEKGFHEVKSGVFRVTALDGSDLVLISPEHWLAICKKKDEEVAPARKEFFLCDLHGAPFEEPFLYRYLGTRMPGFDRYLDVISKALDEGLYSILDQGVDYSADKCKRVIMQPQILHVYSHVIWRVIMGKGFRPEVVDIFEQYSATLIPVMKRLKAQRPIMARITAAFSNEVRHVNAQLEQATAFFTPIFEQYVQAFEQGSPNSEVDNEWFTELVNMAPAEKRRDYKFLTNILIGFAFTFVFSPGPSTTQVVYEFAFRPDYVDQVLEEAHKVLGEQSEHWIFTRDSLRRLSLLDSFCKETHKHHPTAASNLMKKIHKTQTLPNGVVLPAGTIFEVVMTAAHLSNPNLENPAEWNGRRYHDLRQKMSSTTIGSNKYDWGSATRDDVNFGYASHMCPGRWAGCSIAKMFLIKLLASYQIRPEDGVTERYEDLHSGQYILPNPTKHILIRPRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3R104</accession>
    <name>E3R104_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_11939</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697541">
        <property type="protein sequence ID" value="EFQ36792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100812.1">
        <property type="nucleotide sequence ID" value="XM_008102621.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R104"/>
    <dbReference type="STRING" id="645133.E3R104"/>
    <dbReference type="GeneID" id="24417302"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11939"/>
    <dbReference type="eggNOG" id="KOG3105">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1147117_0_0_1"/>
    <dbReference type="OrthoDB" id="4839903at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004875">
        <property type="entry name" value="DDE_SF_endonuclease_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03184">
        <property type="entry name" value="DDE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005673465" evidence="2">
        <location>
            <begin position="21"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="DDE-1" evidence="3">
        <location>
            <begin position="3"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ36792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="242" mass="27422" checksum="BE32AAECA75326AD" modified="2011-01-11" version="1">MWKCWRHNIYLLFLPPHSSAVLQPLDVAVFSLLKQAFCKEVVYLDGWLTDPTIAGRRAFLECYFKARKISTTSQNIRSGWRAAGSWPVAMRRPLSNPLIAKAQQTTSQTSQPSSQRWDEAVSIVPWSTPHRSADLRHQLHQLTQLGQDGLDTHTIRHLCKKVQMGYGEQASRLALLERQVSALQAKLEDQRSRKSKKVPLSPNSTFATIGHIQRTRNTDTGDTDSPDESSEAENCIWMSDKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q1Y8</accession>
    <name>E3Q1Y8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Enoyl-CoA hydratase/isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00233</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089109.1">
        <property type="nucleotide sequence ID" value="XM_008090918.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q1Y8"/>
    <dbReference type="STRING" id="645133.E3Q1Y8"/>
    <dbReference type="GeneID" id="24405598"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00233"/>
    <dbReference type="eggNOG" id="KOG1680">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_7_6_1"/>
    <dbReference type="OrthoDB" id="2018133at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016836">
        <property type="term" value="F:hydro-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000009">
        <property type="entry name" value="Carnitinyl-CoA dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.12.10:FF:000001">
        <property type="entry name" value="Probable enoyl-CoA hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="entry name" value="Lyase 2-enoyl-coa Hydratase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF54">
        <property type="entry name" value="ENOYL-COA HYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ25089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="262" mass="27768" checksum="A8690A114989808C" modified="2011-01-11" version="1">MDNLQTLKLSVDAETAVALVQFNRPAKRNAFSQVMIGELVATLAYLDAHDTVRAVVVTGGPDGPFCAGMDLNELVQISTVEAHQRAFLKDLTDAFAGFSKPIIAAVVGFALGGGCEIALACDIIYAAQDASFGLPEIKIGTIPGAGGTQRLARALGKHKAMEFVLTGDPASGAEFERLGVVNKVFPGPEVVPAALKLAERIALMSGPVIKTAKQAVLTVENSHLDAGMTMEKALYYSTFGLGDFQEGMTAFLQKRRPDFKHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2C7</accession>
    <name>E3Q2C7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_00372</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089248.1">
        <property type="nucleotide sequence ID" value="XM_008091057.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2C7"/>
    <dbReference type="STRING" id="645133.E3Q2C7"/>
    <dbReference type="GeneID" id="24405737"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00372"/>
    <dbReference type="eggNOG" id="ENOG502R98D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_388831_0_0_1"/>
    <dbReference type="OrthoDB" id="5226580at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057194">
        <property type="entry name" value="DUF7872"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF32">
        <property type="entry name" value="MISCELLANEOUS ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25278">
        <property type="entry name" value="DUF7872"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="13"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ25228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="710" mass="79559" checksum="CDCB4D93175DFDEB" modified="2011-01-11" version="1">MQSRKRHAPYGTACSECSRTKSRCIATSPGSPCERCQRLGKDCVPSNHKRTQKSTENDEPSQPSQLEAKIDGLVSLITKNTHETPAGSVFSSSHISLPVTLSPQADGDLLSYINEVSSSINDEDVLSHFKKAHHPHLPFLSLPSDSPPSSLRQERPFLWLCLVAVSESHTLPQAAFNDKVRRIVAQRMVLNLERNLELLQGLLVCIAWGNFQVHQRPFLTLFTQLANTIVFDLGLNQPPQIIPEAMLRLTIHRPWVSGTRTVEEQRAVVACYYLSSIVSSYMRRTDRLLWTRYMSTCLDDLTISGTPGDAALVYVVKISRILDRAFYSPPNSQMPVLETPADFVAAALQTELEKLATEAPYPVESPVIACHHTYASFAISEFTLTLPSPDPQHLYTTYEALKSYFNAFLSFQPSEYSGFTLAELYQTMHAALSLRKLSSQLTTQMYDKQRVEKLADWYQQVIRNLGDASMHPGAKRDGKSAVFRKLASMLEPFTWESGEGLGRQGDNELNIDGITSELTVTGIPSYIDGMMQPPAANQQYVKWSGIADRLSVKPDDYKGVISQHAQNSINAPINNTKYGVNSVLQGGEYLMRSKSFTQDDVEKWMYKTGSINAMGLILQAQNVYITLTFNLSSYSIGKYYTGAFFCQRQPKCAPRILYLNTISRPSFRKPTIFPRRTFPSGTPSASTRTATSSYITPGRRYHQVAPFWIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2H2</accession>
    <name>E3Q2H2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha-L-rhamnosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00417</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089293.1">
        <property type="nucleotide sequence ID" value="XM_008091102.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2H2"/>
    <dbReference type="STRING" id="645133.E3Q2H2"/>
    <dbReference type="GeneID" id="24405782"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00417"/>
    <dbReference type="eggNOG" id="ENOG502SM44">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007933_3_1_1"/>
    <dbReference type="OrthoDB" id="10036721at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.420.10">
        <property type="entry name" value="Maltose phosphorylase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035398">
        <property type="entry name" value="Bac_rhamnosid_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032790">
        <property type="entry name" value="GDE_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34987:SF5">
        <property type="entry name" value="ALPHA-RHAMNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34987">
        <property type="entry name" value="C, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G02880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17390">
        <property type="entry name" value="Bac_rhamnosid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06202">
        <property type="entry name" value="GDE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycogen debranching enzyme C-terminal" evidence="1">
        <location>
            <begin position="9"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-L-rhamnosidase C-terminal" evidence="2">
        <location>
            <begin position="274"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ25273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="401" mass="44369" checksum="9B7B83EF97AA6ED3" modified="2011-01-11" version="1">MNYTLPLFDYPLWWVVCSHDYVWYTGDLEYLSTYYINLVAVLDRWYPSVTDPATGLVTKGLNGTAGYGDYAFVPRQGPVTYYNALYVLALRRAAEMAVEAENDGDAERWRRRADEVAKALGERNFDKEAGAFWDGTNEGQFMDAHAQDGNSIAILADVVDKEKARGMLDYYSRVAARPYGNAFYDSDAVNEGFSQKVYAFVSYFELAARFMVGAGDSAIEEMKRLYGWMSRQDPGVTFWEGIGPEGKPYEDGYTSMAHGWATGLVPLMSGWVLGVKPTEPGFRTWSVAPETAGLRWARGVVPTPRGGGIRVEWEQGGDGDVRIQVRAAEGSRGVVGVPVGARGKVVELDGEVVYAGRDGARARYKEGRVLVDVEGKGTDCKVVVSVRRRPDNPWAFIRQAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2Q8</accession>
    <name>E3Q2Q8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">PQ loop repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_00031</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Vacuole</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the laat-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ24887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008088907.1">
        <property type="nucleotide sequence ID" value="XM_008090716.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2Q8"/>
    <dbReference type="STRING" id="645133.E3Q2Q8"/>
    <dbReference type="GeneID" id="24405396"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00031"/>
    <dbReference type="eggNOG" id="KOG2913">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019699_1_1_1"/>
    <dbReference type="OrthoDB" id="8048523at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098588">
        <property type="term" value="C:bounding membrane of organelle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015174">
        <property type="term" value="F:basic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015101">
        <property type="term" value="F:organic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034488">
        <property type="term" value="P:basic amino acid transmembrane export from vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034490">
        <property type="term" value="P:basic amino acid transmembrane import into vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.290:FF:000011">
        <property type="entry name" value="PQ loop repeat protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051415">
        <property type="entry name" value="LAAT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201:SF35">
        <property type="entry name" value="VACUOLAR AMINO ACID TRANSPORTER YPQ1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="14"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="287"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="107"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="324"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="324"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ24887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="353" mass="39336" checksum="A0364C85DFE8181A" modified="2011-01-11" version="1">MAPPTAPLNLDVEAISGICGSISIACWVVVFSPQILENFRRGSADGLSLQFIIVWLAGDVFNILGAVLQGVLPTMIILAIYYTIADMVLLGQCFYYRGFTWRDEVVPPTPKPRNRTGEPNERTGLLPSALIDRERRGSDWSSLSPAAPMRPESVPAPPPRPTTTIQALLWNTTAVLMVCAAGVVGWFLSREYSRPDEPGHETHDNDALTFNTLGQVFGWLCAVFYLGSRLPQLLLNYRRKSTEGVSMLFFLFACLGNLTYVLSIFAFEPRCKHDECAPGEAGAIYGRYILVNLSWLAGSLGTLLLDMGIFVQYFMYRTDEFATEDEEDDDQSIDEDQWDQRPLLARGDSIHHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3B4</accession>
    <name>E3Q3B4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_00660</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089536.1">
        <property type="nucleotide sequence ID" value="XM_008091345.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3B4"/>
    <dbReference type="STRING" id="645133.E3Q3B4"/>
    <dbReference type="GeneID" id="24406025"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00660"/>
    <dbReference type="eggNOG" id="ENOG502QVF9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009617_1_0_1"/>
    <dbReference type="OrthoDB" id="2283631at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF79">
        <property type="entry name" value="C6 FINGER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="53"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="180"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="686"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="733"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="796"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="12"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="798"/>
            <end position="821"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ25516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="892" mass="99453" checksum="0F1C3869EED4E2EB" modified="2011-01-11" version="1">MSNDPSVRRILPQSSQMGSFSFAPQQFPQRETQKNYVFVDEHNRHKRLKVMRACEGCRRRKIKCDAATTNTWPCSACIRLKLHCVRPNGQYDGTDSYEPGRDEFAATPSQLQDSFRHQASMQQQSMMPGGQKSNPSMFAAQGAYSDPSIFPSVHYSEQPSHQHNLHYTTVSPSVSMMEQPYTGQNVFPTPPLQHSAHPDSPPDTYSQDGSYQQSDLADLLGSLKVNEAGTAPYLRNKASFLHDEEPAVEDAEDFKTPLPPITSGPGLKIRIPPELMPDEETVMHYFDLFFSHVHPYVPVLSKTVFYHQWNTNRESISPLIVEALFAMGGRLADDPAQGQQWLALATKHADSFMDVPRLSTLQALLLILKAREAAPKRGYYYRSWMTIVQCVQMGKDLGLDEHYSDHQLGRPCGSSPTECQMKSRIWQAIFVCETMIGSPQGRTDLAVELDSIDFSVPRPIPGGDDSEYHITRNFTYFARVVRNVSRMNTAYGHLKKKKTKDWGVDPEFVQLNPALNAWLNDLPADLSVTFPPDGSPPWLSSPYIGNMHSYYYLTLILLHRPQLNFLDPNGQDGQWKQHMMICYSAAKALCRLQEAVLNSFGLPGLQCMLRGFSFTVYCGLCCIVLHLVAVVSPDPDLNTDAREFFTRHMRVLERVMTAWPMADLQKQVDAVREAFSADTRKPFVLKPSFPYGSPQSSNHSSPPRGYRPGMGRTTSLGQQLDTQNLQHSQVSYTSHPITPPISAGPMDTKGDSPAIQSLVMMANQGSQAPGLQQSMSLSDAPAWNPARIFEQWNTSFGTPQVQPQPSTLPPQSSSLSVSPSSGAPEAPSLQDIQAVNATLPVVSQQMAQQYSAAPVQTFVSPAMWQESVASVYEGGLKRAWDYDGSGPMMKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q478</accession>
    <name>E3Q478_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_00534</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089410.1">
        <property type="nucleotide sequence ID" value="XM_008091219.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q478"/>
    <dbReference type="GeneID" id="24405899"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00534"/>
    <dbReference type="eggNOG" id="ENOG502SK74">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_3_1_1"/>
    <dbReference type="OrthoDB" id="9976870at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF15">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="38"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="312"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="334"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ25390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="376" mass="40569" checksum="9443AF02716EC91F" modified="2011-01-11" version="1">MSTIDPNQRFLTTLEGTGLSLFVVSIVGGIMSLIVVSLRTHQRLKSGNFKQDDALMLFGLVVYIVDVVFACLGAKSGLGTRNANLNPTMMVESVKYLMIWMLLYITALCAVKASICYTTLRIATTMPRLRIAVYALLGLTVASFLTAFIGVLLLCRPVEANWNQRLIAEGRGKCSSVTSMLALSYTSTAATIVTDLACAVLPAIILWQTQMKLSTKIVVSTILSFGSFASICTMIRTPYIDNYNRPLDDFAYHIGNIPLWSNVETAVGIVAGSLPALRQLVTRHVASQSATKGTSGSSGLAPSSAALVTIGGSGGTNKSKARKGMKSNFEVDDAEHGDWTRLDEDTASDKESTVPIRGIRKETSYAVEMSPFDEHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4H4</accession>
    <name>E3Q4H4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Succinate dehydrogenase [ubiquinone] cytochrome b small subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_00630</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Mitochondrion inner membrane</location>
            <topology evidence="1 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the CybS family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089506.1">
        <property type="nucleotide sequence ID" value="XM_008091315.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4H4"/>
    <dbReference type="STRING" id="645133.E3Q4H4"/>
    <dbReference type="GeneID" id="24405995"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00630"/>
    <dbReference type="eggNOG" id="KOG4097">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096618_0_1_1"/>
    <dbReference type="OrthoDB" id="18577at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098796">
        <property type="term" value="C:membrane protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048039">
        <property type="term" value="F:ubiquinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006121">
        <property type="term" value="P:mitochondrial electron transport, succinate to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03496">
        <property type="entry name" value="SQR_TypeC_CybS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1300.10:FF:000007">
        <property type="entry name" value="Succinate dehydrogenase [ubiquinone] cytochrome b small subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1300.10">
        <property type="entry name" value="Fumarate reductase/succinate dehydrogenase, transmembrane subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007992">
        <property type="entry name" value="CybS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034804">
        <property type="entry name" value="SQR/QFR_C/D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13337">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13337:SF2">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE [UBIQUINONE] CYTOCHROME B SMALL SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05328">
        <property type="entry name" value="CybS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81343">
        <property type="entry name" value="Fumarate reductase respiratory complex transmembrane subunits"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 12" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="binding site" description="axial binding residue" evidence="11">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <note>ligand shared with SDHC</note>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>a ubiquinone</name>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <note>ligand shared with IP/SDHB</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR607992-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR607992-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU364031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ25486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="175" mass="18794" checksum="B5C73D927D53F5FB" modified="2011-01-11" version="1">MASIVRPSLLRQTATAARMTQAAPIRSAFVKNSTRATAFHTTTKRQLLPVGPQVIDGGVNKPAPVPPPSPAHGSYHWTFDRLLAAGLVPITIAPFAAGSLNPTTDALLCAMILIHSHTGFQNIIIDYVPTKHYPKSRKATMWGLNLATALVGLGLYEFETSDVGVTEAVARLWRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4P4</accession>
    <name>E3Q4P4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_01203</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ26059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090079.1">
        <property type="nucleotide sequence ID" value="XM_008091888.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4P4"/>
    <dbReference type="STRING" id="645133.E3Q4P4"/>
    <dbReference type="GeneID" id="24406568"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01203"/>
    <dbReference type="eggNOG" id="ENOG502SIHU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054788_0_0_1"/>
    <dbReference type="OrthoDB" id="4161589at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021833">
        <property type="entry name" value="DUF3425"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012">
        <property type="entry name" value="B-ZIP TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012:SF2">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11905">
        <property type="entry name" value="DUF3425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="34"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="126"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="198"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="80"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="135"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="145"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ26059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="508" mass="56089" checksum="62EE2E1DA8263658" modified="2011-01-11" version="1">MSTALRSIRPRGQVPEDASAPESGAAKSSKGRVACGQCRKLRQKCDTQRPSCSRCLLTKHECVYEADLGETRMQGIRKVNRQLKGEVDTLKSLIERLKSASDEARASIMAQLTANESPEAILQRLSTDQGAAQERTVETSRESASETGQSRQTTTTASITAFVKPEEDDELPLPPGIVPWQIDKMHYLLNGVDSIDINDKSSDAQSSTHPADAQAPGSEGGEEDRERESTELIYALLLADQAARRRSQSSSSAGPLPPGAVGAFGNLPLSCAVRANYYPPAVQARQLLNLRAEEYRLPSFINPDGSPLSSLFYTYRDAALEMLSNGVPSFQVLGPSDRIDIELFFRDREPHDAYDVHSWACELMKNIEGYDVFVQLASIALSATYMRWNILPTASNYALMPEMIRPTHRQRFIPHRMTIDLVPHPAIRNALISRFRDWLSPGTTDTGGTSVGWPYSLEAAVDVCPITGRRMLSRAFVEHATNGSNWSLDKSIRAIFPEIEAMGFTIRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5K7</accession>
    <name>E3Q5K7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_01118</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089994.1">
        <property type="nucleotide sequence ID" value="XM_008091803.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5K7"/>
    <dbReference type="STRING" id="645133.E3Q5K7"/>
    <dbReference type="GeneID" id="24406483"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01118"/>
    <dbReference type="eggNOG" id="KOG2614">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_3_2_1"/>
    <dbReference type="OrthoDB" id="47494at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47178:SF1">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47178">
        <property type="entry name" value="MONOOXYGENASE, FAD-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="12"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="319"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ25974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="419" mass="46728" checksum="BA10C17888E2DE12" modified="2011-01-11" version="1">MADQDQVPGPLPVIIIGAGVSGLLLAQYLRKTTVPFRIYERDADLTTRGVGWGLTLHWSLPALRSLLPEDLVARLPEAYVDRAAVTRGEASAFPFFDLSTGELKGASPRAPESLRIRVTRERLRRLIATDVDIQWEKSLARYEEKQDSVDVFFEDGSSVTGRILVACDGGPSRVRRQLFPDQHARYQIPVRVLGLKVFLSPDQMAPMRELDPFFLQGTSSRNDTFLYFSMLGAPGNNDESTGQYSCQMCISWPNRPGFLGKQEPTDYPQTNAGKIELIKSFAEGWSEPFRGIALGIPHDTDVKQLDLYDYPPPKGLRSKGRVVLMGDAFHAMAMYRGEGANHAILDVLDFAENVTPKLDAGFTDVRTAIDAYEDEVVARARPGVLASRRACMDAHDWPKISPTSPLLSKREMKLHFDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5U5</accession>
    <name>E3Q5U5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Histone-like transcription factor and archaeal histone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_01337</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NFYB/HAP3 subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090213.1">
        <property type="nucleotide sequence ID" value="XM_008092022.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5U5"/>
    <dbReference type="STRING" id="645133.E3Q5U5"/>
    <dbReference type="GeneID" id="24406702"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01337"/>
    <dbReference type="eggNOG" id="KOG0869">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066247_10_2_1"/>
    <dbReference type="OrthoDB" id="386949at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016602">
        <property type="term" value="C:CCAAT-binding factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22907">
        <property type="entry name" value="HFD_NFYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000110">
        <property type="entry name" value="Nuclear factor Y, subunit B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003958">
        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027113">
        <property type="entry name" value="Transc_fact_NFYB/HAP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003956">
        <property type="entry name" value="Transcrpt_fac_NFYB/HAP3_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11064">
        <property type="entry name" value="CCAAT-BINDING TRANSCRIPTION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11064:SF9">
        <property type="entry name" value="NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00615">
        <property type="entry name" value="CCAATSUBUNTA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00685">
        <property type="entry name" value="NFYB_HAP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0010">Activator</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription factor CBF/NF-Y/archaeal histone" evidence="9">
        <location>
            <begin position="46"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="133"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ26193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="203" mass="22081" checksum="DD863E79901E4998" modified="2011-01-11" version="1">MSDSPQSPPKDVDQGVQSPEEEQMNEPQDPQSGGLTYEFEVKEQDRWLPIANVARIMKNALPENAKIAKEAKECMQECVSEFISFITSEASEKCHQEKRKTVNGEDILFAMTSLGFENYAEALKIYLSKYREQQSQSNRGEGAHRPSSSGYGANPPTGAGSFQAEPQNNVLGGQQADGSADAQGYMYGAQTSHNGTGGGDGYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6F8</accession>
    <name>E3Q6F8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_01550</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090426.1">
        <property type="nucleotide sequence ID" value="XM_008092235.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6F8"/>
    <dbReference type="STRING" id="645133.E3Q6F8"/>
    <dbReference type="GeneID" id="24406915"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01550"/>
    <dbReference type="eggNOG" id="ENOG502SHR2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027370_0_0_1"/>
    <dbReference type="OrthoDB" id="5343576at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="485"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="516"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="583" mass="64099" checksum="AB468B8F56B86871" modified="2011-01-11" version="1">MGWQRKVSPSPQTSNTASSRHLMPHLTCSEREDTNSGMNYIHLTQTLVESFNALADEVQILTDRKTILEHKLRFAHEQYQYIADKYAPAAPEISEVLAKLQLPPELANPSLEDANPVPLPRRNKLDTRNQIALIIRDGRRVAQQLTSIGETSKTSDSSRETSSREARTVTSMSTVLEQDFTIEGKKGSLECPFSSPKAEGDGVGDAHNAEGGSQDPTPHHSADPICAAMFEESTSQPAPGAADSPAKCPIRYLDQHSPEEIAHYVETHKHELPRSHEVCVRRYQKNEVQIKKLDAKYGNLVNMIQGLSALHQPMLPESQREQEEIDRASNERVHNWAKDVTVSETEDAEQSLPAPMDADEVRQSHFDRPLKEVRVGESPSRPWGISVPIYESHGLGGEERPLSPPPAPVFMPSGSEGEETPAPKTGKCPFDHTKMAAMATALEEVQPPSPTRAPNLMSNGMSDNVSPQKAGGECPFDHAQLAAMGFASPTPNTGEQTFVHADPDPVELPSTPVKPQPSQSAPAPIQPQQQQQQLPPTFINPPLDANKQFNSNGVPQMVFTGPVFIGYPIEQAIQFMQHFQGRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q741</accession>
    <name>E3Q741_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF7728 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_02499</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090699.1">
        <property type="nucleotide sequence ID" value="XM_008092508.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q741"/>
    <dbReference type="GeneID" id="24407864"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02499"/>
    <dbReference type="eggNOG" id="ENOG502SC3G">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038083_1_0_1"/>
    <dbReference type="OrthoDB" id="5409353at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056145">
        <property type="entry name" value="DUF7728"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40622">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40622:SF1">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24854">
        <property type="entry name" value="DUF7728"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178251" description="DUF7728 domain-containing protein" evidence="3">
        <location>
            <begin position="19"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="289"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7728" evidence="4">
        <location>
            <begin position="51"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="336"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF24854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ26679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="379" mass="42351" checksum="D36E32918F5E8E12" modified="2011-01-11" version="1">MLLKSLAAASLAIKATQAFIVVPEISQADSEIVNTLPFGLEDPSIEMGLASHRVKVDCPGCPLAMRHYDGRYHTMSNINNHLELTFSIDTDTSGVDHLLVNDFELYPKPASWYKALRAPQIPDFTEAATKHPRKASPNTPQLGYSLGVRPVAKDTEQQLELVEIDLQIIEVGNSFVSDIPNVNVKLIKSPTGNLMIANIEQTETSVPSRQEEEQEEVEDHVEAPAEDCTTFYCKWRAAILNKMHRMKHCGGRKNHGAMHGQHRHGHHNGQVRHHHHTWAQLAKNVASHILFPVLIGIVAGVSVSIIGMMVGTFVVCLWRVFVRRQPPFARRHCRRRARKSVHREAAAVEEKSGLMADSEDLPPYKDNEEDACKTETAQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7F7</accession>
    <name>E3Q7F7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_02615</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090815.1">
        <property type="nucleotide sequence ID" value="XM_008092624.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7F7"/>
    <dbReference type="GeneID" id="24407980"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02615"/>
    <dbReference type="eggNOG" id="KOG2504">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_1_1_1"/>
    <dbReference type="OrthoDB" id="5212574at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF130">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="144"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="252"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="315"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="344"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="381"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="410"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ26795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="446" mass="48147" checksum="F21D80930F4B7361" modified="2011-01-11" version="1">MDGTDKETRSDSSRDDGVGGEPVRTGSRVGRVLSRIASTPTSDPGPPPDGGYDAWMAVLSAHFIFMDTWGFVNSFGVFQTYYVRQLGRPPSDISWIGSFQVFLLFFVGAFSGRFTDAGYFRHLFLCGSFLVLLGIFATSWCTQYWQIFLAHGVCVGLGFGLVFCPSLATLSTYFDRRRALAIGIAAVGSASGGLVFPSTVRQLLPRVGFPWAMRTLGFIQLATLSVGLVFLKPRIPPRRASKLVDLSAFKELEYTFYTAGGFFSFMGVYFAFYYLASYSRDELGFSYTDSLNLLLVLNGIGFVGRLGPNFLADKVGTITVFTPMALLSGLLMYCWIAVGSATGLYVWTVFFGVAGNAIQSLFPAGISALTTDPSKQGSRIGMVFTVVSFAVLTGNPIAGAIVSATGGRYLGAQAFAGSCLMLGAFFLALARVVKTKKIGHGWFVKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7S0</accession>
    <name>E3Q7S0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_02103</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EFQ26932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_008092761.1"/>
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        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
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        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="NPHP3-like_N"/>
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        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="6"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="16"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="11"/>
    </dbReference>
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        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="NACHT-NTPase and P-loop NTPases N-terminal" evidence="5">
        <location>
            <begin position="8"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="6">
        <location>
            <begin position="259"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="768"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="836"/>
            <end position="868"/>
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    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="869"/>
            <end position="901"/>
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            <begin position="935"/>
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            <begin position="1015"/>
            <end position="1047"/>
        </location>
    </feature>
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        <location>
            <begin position="1048"/>
            <end position="1074"/>
        </location>
    </feature>
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        <location>
            <begin position="1083"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1156"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
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            <end position="1221"/>
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        <location>
            <begin position="1224"/>
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        <location>
            <begin position="172"/>
            <end position="201"/>
        </location>
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            <dbReference type="ARBA" id="ARBA00022737"/>
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    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ26932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7S3</accession>
    <name>E3Q7S3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Riboflavin kinase</fullName>
            <ecNumber evidence="4">2.7.1.26</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Flavin mononucleotide kinase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">GLRG_02106</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>riboflavin + ATP = FMN + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14357"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57986"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; FMN biosynthesis; FMN from riboflavin (ATP route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the flavokinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.26" evidence="4"/>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ26935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090955.1">
        <property type="nucleotide sequence ID" value="XM_008092764.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7S3"/>
    <dbReference type="STRING" id="645133.E3Q7S3"/>
    <dbReference type="GeneID" id="24407471"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02106"/>
    <dbReference type="eggNOG" id="KOG3110">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022880_1_0_1"/>
    <dbReference type="OrthoDB" id="276388at2759"/>
    <dbReference type="UniPathway" id="UPA00276">
        <property type="reaction ID" value="UER00406"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008531">
        <property type="term" value="F:riboflavin kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009398">
        <property type="term" value="P:FMN biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.30">
        <property type="entry name" value="Riboflavin kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023468">
        <property type="entry name" value="Riboflavin_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015865">
        <property type="entry name" value="Riboflavin_kinase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023465">
        <property type="entry name" value="Riboflavin_kinase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22749:SF6">
        <property type="entry name" value="RIBOFLAVIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22749">
        <property type="entry name" value="RIBOFLAVIN KINASE/FMN ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01687">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00904">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82114">
        <property type="entry name" value="Riboflavin kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0288">FMN</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Riboflavin kinase" evidence="15">
        <location>
            <begin position="537"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="14"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="175"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="188"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EFQ26935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="743" mass="78613" checksum="2B75F9980E9C7D29" modified="2011-01-11" version="1">MYAPDAATFRRKPLPGPPPGPPPPPPDFDPFPQRHQPLRGARSTPNLRQSATPSIYDPPPAYEEFPGVNSRGRLAVDPPIGPGPRSGRAPSPSPSPRQEYRPYRPQAPPSSGRGEQSASFPLPSPAPSAFGGYPAEPAKSARPEILPYRPPQPSSNFGPGGRPSPAPSDYEGYFPGPPVTAPPEKSPYQLQPSSTFNSGKQSLAPPSPGPYFPAPTTTATTDSQATAEKSFWQTALEETKYFAGGLVSHPFEYTKHHSILRHSGALVWYRGPSTSVTVTVFSDAPLPPTRTVWLQQKGFSGNMGMNLKSLVGATTSWLDVTPSTRAAPADLADADERGCQRDIRKFLRKAPKNLAAHAPRETHVVRIPAAADDGYFRLVLCSGGGGDGTKRKVLCPSPVFRVASTSTDASVVRGASLASMPLEIGIKAGSVVAATVVNKYIGPAAAVVQARAKTLSKAKVVTKHAAHAANIAHVAQVKGGIDKSGIRTHVAAFEDRYAAARGAGYDAWQSGDAAGAGFQEAPPEVVGSDDGPSEPFPIKFDGRVARGTGRGGAELGVPTANLTDVPGDVRVRMRGVYFGWARVVLPEAMATTVSADWHESLVTVGPAPYATPRVAAKNVATVHLIHEFGGAQFLGARLKVLVMGQLRASAPPADGSDAALAAYGADVLLAVASLSRENWGPEETRERLRATRSEMSLADRYVEARDRVQKQVDRVPLHLAGVRTEGAALRDRAFGNGGLWIPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8D2</accession>
    <name>E3Q8D2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Mitochondrial distribution and morphology protein 34</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">MDM34</name>
        <name evidence="13" type="ORF">GLRG_02315</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Mitochondrion outer membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <text evidence="10">The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.</text>
    </comment>
    <comment type="domain">
        <text evidence="10">Lacks alpha-helical transmembrane segments, suggesting that it resides in the membrane via beta-sheet conformations similar to those predicted for other outer membrane proteins and porin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the MDM34 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091164.1">
        <property type="nucleotide sequence ID" value="XM_008092973.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8D2"/>
    <dbReference type="STRING" id="645133.E3Q8D2"/>
    <dbReference type="GeneID" id="24407680"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02315"/>
    <dbReference type="eggNOG" id="ENOG502QT3W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036502_1_0_1"/>
    <dbReference type="OrthoDB" id="17927at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032865">
        <property type="term" value="C:ERMES complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990456">
        <property type="term" value="P:mitochondrion-endoplasmic reticulum membrane tethering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015914">
        <property type="term" value="P:phospholipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21673">
        <property type="entry name" value="SMP_Mdm34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03105">
        <property type="entry name" value="Mdm34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027536">
        <property type="entry name" value="MDM34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058825">
        <property type="entry name" value="MDM34_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28185">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY PROTEIN 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28185:SF1">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY PROTEIN 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26545">
        <property type="entry name" value="Mdm34_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="7" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 10" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 10" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SMP-LTD" evidence="12">
        <location>
            <begin position="1"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="295"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="364"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="534"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="364"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ27144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="556" mass="60862" checksum="A824D7D22BF7EEFF" modified="2011-01-11" version="1">MAFNFNWSPLTADAEFYQRAREMLTTALNKSPKPPIIVDDILVTEFNLGSVPPELEILEIGDIAEDRFRGIFKMCYSGDAFLTLKTRVQANPLNTYLSSKPGFTSPQPLAAASGLTIPLSITLSEIKLSAFIILVFSRQKGLTLVFRNDPLESLKVSSTFDSIQFVRDYLQRTIEAQLRNLMMDELPAIIHRLSLRLWCPDSLPKEDETPKEDAEETEVYPLASPPLDPVDANGNLLDANEVSSLSLEGGPEVQSLFSQKNLLRLAALNDSHRTFSLFTPGIRDVVFRAWTGPAVSEPTSTPPTATPSLSKTNSFHGTSTTYTFSDTGSASHGHLPSRPSMVSLNSATTGLSLGAGIRSKSYAGRKKKTRVVNLRRSKSEVGETPEDSETQSEMASETASVAGPSTEPLMASSIAEDPEEEEALANLAESTPSKVRFGPMEKTRFPSRPPLQPNFYTAPKDVPSVPIKLDSTRKAEAAAQPQSQTAKEAGAFPSEKANAEKQPNGDSSETSTVYEQAWIMKMAGEIARRVYDEKSRHPDLWDEREDIPPPAYEASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8D9</accession>
    <name>E3Q8D9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02322</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091171.1">
        <property type="nucleotide sequence ID" value="XM_008092980.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8D9"/>
    <dbReference type="GeneID" id="24407687"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02322"/>
    <dbReference type="HOGENOM" id="CLU_1758663_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="148" mass="15855" checksum="4AD5AEE6B7836BAD" modified="2011-01-11" version="1">MQAVAATRTINGRPTSRPPNARSVRSPDSELLWIALSRPKPFPHEARQPDPIHRHWEPTRRPGKGYSGNDRSLLGVNVSEDDVWFAGKDGFLLIYGARGCAGAEALRSGRTQPEGAGSHYPVIAWGGPQPAGLCQASGAHPYRGIGGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8J8</accession>
    <name>E3Q8J8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_02040</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ26869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090889.1">
        <property type="nucleotide sequence ID" value="XM_008092698.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8J8"/>
    <dbReference type="STRING" id="645133.E3Q8J8"/>
    <dbReference type="GeneID" id="24407405"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02040"/>
    <dbReference type="eggNOG" id="ENOG502S30A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042179_2_1_1"/>
    <dbReference type="OrthoDB" id="2152029at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF31">
        <property type="entry name" value="STERYL ACETYL HYDROLASE MUG81-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="3">
        <location>
            <begin position="123"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ26869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="386" mass="43289" checksum="ADAA1B5595B5D203" modified="2011-01-11" version="1">MKAPRPQLSLWEKRDLVFRLLFRAPLQLIWNFAYGMPFAAARGVSVWFFAICAYYRFALGCMRAREIQFLLPPSLRTYEKWIAKKRKRHPEHAGKLKKHIEMLPANDGSIMWIGDRQKATKFVLFFHGGGYVVPLLPGHLEWCWESYVNGGPGEHAEVAVAVLQYTLVPEARYPTQLQQAIASLNQLILSGIEPRDLIIGGDSAGGNLACSVIRHICHPCHLEIPALRLESRLAGVFLVSPWLTSKTKASSFKENNYVDMIKATAVCNGTAELLHPRFPVRNKSDESDLAMAMPMDGDMAWVDDISTATASLYITAGQQEAFRDDIRSFSEHLSCGNNDLDLLLELSEHEAHDFILLEGQTRRVGDATVRMRNWAAAQLGTGRSPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q913</accession>
    <name>E3Q913_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Leucine rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_02022</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091547.1">
        <property type="nucleotide sequence ID" value="XM_008093356.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q913"/>
    <dbReference type="STRING" id="645133.E3Q913"/>
    <dbReference type="GeneID" id="24407387"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02022"/>
    <dbReference type="eggNOG" id="KOG4308">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027887_0_0_1"/>
    <dbReference type="OrthoDB" id="333024at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045203">
        <property type="entry name" value="RanGAP1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46761">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46761:SF2">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ27527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="704" mass="76667" checksum="977AE855C336ED27" modified="2011-01-11" version="1">MASAATLVLTSTPSILGGFEPLSNGAAKAPSIDTNQTDSDDATRVNVDEAIRLAALFRQASNLLDAQMPDFNHSKAYTPDEILALPIDTIRLPDELHGLPRRKSRRSHLAGVIASLLYPATYDDAVSPVIRYEATRVRLRAWVALQRKYDIFAATKRNGHSFRGLTGGTAPGVHAPVWASRILAQGPWDPAKAPVSLTGAKAIPMPVAVAVAADLAPFFDHLEQRGTHALDEGSAGAALEDGKGKPYYGVKGAEFRKGVVYEDGRMDLCKMAVGPDHIGNLMDSLRPNPFVRHFLLGNNVIGPVGAREIGRFVRELPGRMNTWYLAGNCIDAPSFKTLVDAMVESEAVTNIWLKRNPLGPAAAADVYRLITETKNLRTLDLDQTELGDAGTAELFRRLAAFSVANPGRKQLPLCNIYLNGNGISTKAAVAIAEFLGSPACGITSLYLSCNPLGDEGTKALVSGIRKAHQLSRLSLQSTGLTAAGASDVFRAITTHPGVRFLDVGQAYATVDLGQAWNYINNDAVPLICELVSTNQTLQYLNLGCCPISPPELRKIDTAVLESSLLFYFAVPILPNAKVRVPSFNPSADHTMPDLHSLSAPTKDEKVLEKAVNRHLERNVKATYGDDMTYAKFLEQEKRWIVNDKTDVRKIDSVYRNRDASLARRKLQALAKDWDENDDTLARIMNAKGPFCTVRKHTEILTEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q961</accession>
    <name>E3Q961_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_01735</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091260.1">
        <property type="nucleotide sequence ID" value="XM_008093069.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q961"/>
    <dbReference type="GeneID" id="24407100"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01735"/>
    <dbReference type="eggNOG" id="ENOG502R6FV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1643590_0_0_1"/>
    <dbReference type="OrthoDB" id="4848194at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178306" evidence="2">
        <location>
            <begin position="17"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ27240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="161" mass="16594" checksum="81D3DF38D17E2FE3" modified="2011-01-11" version="1">MKVSTVALALSGGASALPAFSNLVARQPTDLTNRKVEFKGAEAPSLIDDMTFSRAKTVAVRDEVVANTGKRSLVAEPREAAAPASDTGLRTEAIGDNKENPTTGLTDSDAAEIVTSIDFSDKQAPGSLNAKGQRNPLPGLTAEMTDAIINQGQAALKEAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9S4</accession>
    <name>E3Q9S4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">KRR1 small subunit processome component</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">KRR-R motif-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_02756</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. Essential for vegetative growth.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3. Interacts with snoRNA U3. Interacts with MPP10, KRI1 and with ribosomal proteins RPS1A, RPS4A, RPS4B, RPS8A, RPS8B, RPS11A, RPS11B, RPS13, RPS24, RPS25, RPL4A, RPL7B, RPL8, RPL23, RPL25 and RPL28.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
            <location evidence="1 11">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the KRR1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091632.1">
        <property type="nucleotide sequence ID" value="XM_008093441.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9S4"/>
    <dbReference type="STRING" id="645133.E3Q9S4"/>
    <dbReference type="GeneID" id="24408121"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02756"/>
    <dbReference type="eggNOG" id="KOG2874">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040185_0_2_1"/>
    <dbReference type="OrthoDB" id="441223at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd22393">
        <property type="entry name" value="KH-I_KRR1_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22394">
        <property type="entry name" value="KH-I_KRR1_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.10:FF:000011">
        <property type="entry name" value="KRR1 small subunit processome component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.10:FF:000014">
        <property type="entry name" value="KRR1 small subunit processome component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041174">
        <property type="entry name" value="KRR1-like_KH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048550">
        <property type="entry name" value="KRR1-like_KH1_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048548">
        <property type="entry name" value="KRR1-like_KH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048549">
        <property type="entry name" value="KRR1-like_KH2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024166">
        <property type="entry name" value="rRNA_assembly_KRR1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12581">
        <property type="entry name" value="HIV-1 REV BINDING PROTEIN 2, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12581:SF0">
        <property type="entry name" value="KRR1 SMALL SUBUNIT PROCESSOME COMPONENT HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17903">
        <property type="entry name" value="KH_KRR1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21800">
        <property type="entry name" value="KH_KRR1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006515">
        <property type="entry name" value="KRR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 11" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="6 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 11" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="K Homology" evidence="13">
        <location>
            <begin position="123"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="275"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="275"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR006515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ27612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="324" mass="37171" checksum="86180ECB2B6F5ECF" modified="2011-01-11" version="1">MPSTYKKEKPWDTDDIDKWKIDAFTPADNAGGTFAEESSFAIVFPKYREVYLKEAWPLVTKALEKTGIACSLDLIEGSMTVKTTRKTFDPAAILNARDLIKLLARSVPAPQALKILEDGVACDIIKIRNLVRNKERYVKRRQRILGPNGSTLKALELLTQTYILVQGSTVSVMGPFKGLKEVRRVVEDCMANIHPIYHIKELMIKRELAKDPELANESWDRFLPNFKKKTLSQRRVPLKVTDKSKKVYTPFPPAPEKSKVDKQIETGEYFLGKEAKAKAAQAERMEQQKQKKEERLREREKEFVPPEELGHKRKKRKKSDGDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9X0</accession>
    <name>E3Q9X0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Plasma membrane channel protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_02802</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091678.1">
        <property type="nucleotide sequence ID" value="XM_008093487.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9X0"/>
    <dbReference type="GeneID" id="24408167"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02802"/>
    <dbReference type="eggNOG" id="KOG2513">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010867_0_0_1"/>
    <dbReference type="OrthoDB" id="296386at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032541">
        <property type="term" value="C:cortical endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007632">
        <property type="entry name" value="Anoctamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049456">
        <property type="entry name" value="Anoctamin_N_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049452">
        <property type="entry name" value="Anoctamin_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12308">
        <property type="entry name" value="ANOCTAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12308:SF73">
        <property type="entry name" value="ANOCTAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04547">
        <property type="entry name" value="Anoctamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20877">
        <property type="entry name" value="Anoctamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="186"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="219"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="290"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="328"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="376"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="518"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="565"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="609"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="domain" description="Anoctamin alpha-beta plait" evidence="7">
        <location>
            <begin position="21"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Anoctamin transmembrane" evidence="6">
        <location>
            <begin position="178"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ27658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="732" mass="82941" checksum="733C7F1C74607C72" modified="2011-01-11" version="1">MASFSDLYSNEKTKGLDSNFGVDFVINYKIPQEDRAVAEAGFVQLVEALTHVGLTTEVRRGDKQSVLVFIKIADKFLDDQVYRSRLQDWLQGVRTTSSDKDLSQALRDEPVSDAERLRLVYLLIVKPKNEGGAGITPQSGRWKHVDSIFPLHNHAFNKQWIKRVSTKGQTDETDLDEIRDKFGESVAFYFAFMHTYFKFLAVPAAAGFAAWVLLGQFSWFYALVSCLWSVVFFEFWKKKEVDLAVQWGVRGVSNIQHPRPQFEFERQAEDPVTGESVKIYSPIKRLQTQLLQIPFAAACILVLGTLIVTCNSLEIFINEVYNGPFQSYLAFLPTVILVVMTPTFSTVLTKFATRLTEMENYETIDAHHAALVQKEFVLNFLTSYMALFFTTFVYLPFGDRLTPYLDFWRSTAQKITPKDVNFQTQEFVVNPDRISKQMFYFTVTAQVVNFATEVIVPYVKRQVFEEVREVQSKMSKEGDAAHIKDHPEESAFLERVRKEAELETYDVTGDYREMVIQFGYLSLFSVAWPLAACCFLVNNWVEMRSDAVKIAISSRRPIPWRADSIGPWLNALGFLSWLGSITSASIVFLCSSSGKGSGPHSAPGSIQAWGLLLSILLAEHFYFAAQFVVRLVMTKLESPGLQKEKKERFVMKKRLLEENLGQGVSDQAATPGIEKTEMITLKTLEEEARRLSTQGHGGAEEAFWLRQRGMGEVIQIGRNLISQSVAGNSTKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAL5</accession>
    <name>E3QAL5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Variant SH3 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_03047</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ27903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091923.1">
        <property type="nucleotide sequence ID" value="XM_008093732.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAL5"/>
    <dbReference type="STRING" id="645133.E3QAL5"/>
    <dbReference type="GeneID" id="24408412"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03047"/>
    <dbReference type="eggNOG" id="KOG4575">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002511_0_1_1"/>
    <dbReference type="OrthoDB" id="6129702at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110085">
        <property type="term" value="C:mitotic actomyosin contractile ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140278">
        <property type="term" value="P:mitotic division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11889">
        <property type="entry name" value="SH3_Cyk3p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000168">
        <property type="entry name" value="SH3 domain protein (Cyk3)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.620.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052557">
        <property type="entry name" value="CAP/Cytokinesis_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035553">
        <property type="entry name" value="Cyk3_SH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056409">
        <property type="entry name" value="Ig_CYK3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46333">
        <property type="entry name" value="CYTOKINESIS PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46333:SF2">
        <property type="entry name" value="CYTOKINESIS PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24584">
        <property type="entry name" value="Ig_CYK3_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07653">
        <property type="entry name" value="SH3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00460">
        <property type="entry name" value="TGc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="11"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="114"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="179"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="395"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="187"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="201"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="274"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="290"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="335"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="454"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="508"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="546"/>
            <end position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ27903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1279" mass="141287" checksum="CAD621EDA40031D1" modified="2011-01-11" version="1">MVPAPPSLPTRFPCWCRAVYSWGGESKRDLGFIEGDLIECLNAGDGSWWTGRLWRDRRTIGVFPSNFVEVLPSDFRPTTRSASPLPADTPSPSTPQKSRTFRKPFEAYSKAPHYTAAKQPEVYRTNPNTRPRGHSGESIHSAMVEQSRRDRSPAPEAYVSRENSFNSAVSNRMRAYTSPAPTGYVSRGNSFNDGEQQYTSRGRTPVPRARTPVPDYGHGSRVNSFNTERGPSPIPPSQGYSSRGVSPAPSISYKPYRPPTRERVDSPPPPAPPPHRHVAASRHKQSISYDSRHDVSRQESNASHDNRFHPGRQGSGNSFDKRLDFMRQDSTASYENRHSTSDRQGSHLSYQAHRPPPIQTSRLHSPCPPSPSASHMTPSPLREAMDGVIEQLDALGMPRDPTPEPPLDPWSPESFNMVNDRARRRNTYQRPQTSMGIAQPDEGYETWSGGSSRDQSHQNGHREDKEQLPQLSNYVERMESRLKKMHQHSASMADLEDEAPKPPPKGQLYERPKSSMSGPEERKLNKRKSAYDIGRNVLNRTFTTKTNSTSASSGNQSSTTQSSDRSLMSGSSAGAISATSAGSLARKTQKRAQSALGMRDVDVERPETPFTGITYHSSHASDAARPKSTVGFHDDAGLGGLVTPKPAKRSIFKKLLDTAKTGVASGRSSIAMGADSPRSSPFARSMPNVAAGANASISNLSAMGSSGLTREAARDMGPANGVDWVQVRRDVNRSNSLSKNERDERKDRCQMLDYPALNPIDELFEGMEGDEGADGMPVEDPIDYQSLNLTQVDKNSRFVSSLPATITAQSVATTYVCRPYRSDVQRLRAIFTWVSEKILWEEDFEGVVDTRRVVQSKRASAEEYAVLVMEMCSAVGIQCEVIHGYLKTPGEIPEHNIMPRANHWWNAVLVDNEWRMMDCCMASPSYPRRHLYSSASSNVADFWWFLARPTELCWTHIPEHHTQQHICPPQAHEVLLNLPCACPPFFKNMLEMVDYNTAATRIEDLEMVHIKFNTPPDVEVAAEVEVRAYTRDADGDVFESGEVVRKRALAQAEWFNGTKRYTVKALLPGDEGQGVLKIYAGKRGLMHSIKDIPHPVAFALPIIHTGENPPYEFVTRHPTPHAQRHDIYVVQPQCQRLALNNTFVFAIRQHPSSVGGGGSAMTPSSNPGGASPIPFARPGSAMSMTASIASGSNLSSVAGGGKKPAKLAIQTPGGKILRLMRKEERRGVSVGSRAVEDDLGDGGTWETIIKCSEKGVWRGLVLADRTARWCVFAEWVCVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAU0</accession>
    <name>E3QAU0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_03122</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ27978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091998.1">
        <property type="nucleotide sequence ID" value="XM_008093807.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAU0"/>
    <dbReference type="GeneID" id="24408487"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03122"/>
    <dbReference type="HOGENOM" id="CLU_2183750_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="109" mass="11576" checksum="B3324993E566754E" modified="2011-01-11" version="1">MQRVAARLRFAANASVNPGSALAEAPSAAVSAVTSAAPSLVQRNAHVQTILLDRLWQTGYGLKKLPSSNPQPAKRNVQWSVPAIQFRADGKPQADMGMIRAGSRDGQVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAU2</accession>
    <name>E3QAU2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Homeobox domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_03124</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 3 4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Caudal homeobox family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ27980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092000.1">
        <property type="nucleotide sequence ID" value="XM_008093809.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAU2"/>
    <dbReference type="STRING" id="645133.E3QAU2"/>
    <dbReference type="GeneID" id="24408489"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03124"/>
    <dbReference type="eggNOG" id="ENOG502SA0C">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017274_1_0_1"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009948">
        <property type="term" value="P:anterior/posterior axis specification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047152">
        <property type="entry name" value="Caudal_homeobox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24332">
        <property type="entry name" value="HOMEOBOX PROTEIN CDX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24332:SF9">
        <property type="entry name" value="HOMEOTIC PROTEIN CAUDAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 4 7" id="KW-0371">Homeobox</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="6">
        <location>
            <begin position="198"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="3">
        <location>
            <begin position="200"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="17"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="72"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="349"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="444"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="77"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="122"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="160"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="171"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="349"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="383"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="457"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="470"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="502"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="527"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="539"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="644"/>
            <end position="655"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ27980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="666" mass="73172" checksum="420195C570591B1C" modified="2011-01-11" version="1">MLASRQFDTIEQSHWSFSKFETPLNKAPTTPPRMSDDQYETTLPTPPEWQGQQYAYLSSPENNTFSQAYCAGDESSEFTQPRTAASARTQAHIQGKQEHNAAFRLMKQPTPEDEPEDRLREQQQQQQQQQQQRQASQPLEKAAKMMATPEQEAETVAARMDNDEANTSKESDDDALEDEDMLDGGDGTPQTAAERTAARRKMKRFRLTHQQTRFLMSEFAKQPHPDAAHRERLSREIPGLSPRQVQVWFQNRRAKIKRLTADDRDRMIKMRAVPDDFDNIQALHSPYGAVHGLSTPLSSPMNFGTQSYADHMIRPLMVDVRRPEGEDEQMSNSGMSPGFPGIGFASAGNMNTPEVLSPMTPSSTGDNRYGYGSHLTPMGPGPRTSNSFARQGAVETSMSMHRGQPSRPLQPLQLRETMSLSRQDIQSPLRSSMSWKGDAIDYNTYNHGPGASPPLSGRQQSLYQPEQVNGPSSSGLPYESSSYSGTSSPPGMNYSSFSQGPLSRLRSRASSATLGLDLRSPYRPIGSGQSAGHSSAPRSTSTQFATTTAYTSSFPSAPLTAPLDFSLPRTPGNRSGGVHDYSMPQMSAPIAPPHDFSQAFHASMNSSNARTPMRDTFGGGGPMPTHHENQQTHSSDYQLRRQRSYSGGAPAGSGPAPVPQVYGSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAY0</accession>
    <name>E3QAY0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_03162</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ28018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092038.1">
        <property type="nucleotide sequence ID" value="XM_008093847.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAY0"/>
    <dbReference type="STRING" id="645133.E3QAY0"/>
    <dbReference type="GeneID" id="24408527"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03162"/>
    <dbReference type="eggNOG" id="ENOG502SH2S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051875_1_0_1"/>
    <dbReference type="OrthoDB" id="5425061at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018555">
        <property type="entry name" value="C630.06c-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09428">
        <property type="entry name" value="DUF2011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="169"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ28018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="267" mass="29555" checksum="71510421105820E8" modified="2011-01-11" version="1">MLTWVPTHDRVRREDLDDSSEDEASGHDEQQDAELLAKLHARMAGMLDLSGIDQAPAMAAAEEDAVMAEDPGRDTQHDDGPEEFEFRLFTTTDPATKIALVDEDERALLGDGAMLRGRPLSYYIAGEPTPEARAEMAFAAVSGDEVLARARQRWWGMEMPWRVTRVPGASGTAAAAAAGEEETAAARRRRPGKKKRVALRLRERERKKKAEEQEKAKMSKEEALKEKKKRLNRLKKLRKRAKAKEGKKGDGEGEDDESGSGSDGGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3QB69</accession>
    <name>E3QB69_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">5'-AMP-activated protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_03251</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the 5'-AMP-activated protein kinase beta subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ28107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092127.1">
        <property type="nucleotide sequence ID" value="XM_008093936.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QB69"/>
    <dbReference type="STRING" id="645133.E3QB69"/>
    <dbReference type="GeneID" id="24408616"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03251"/>
    <dbReference type="eggNOG" id="KOG1616">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026512_1_0_1"/>
    <dbReference type="OrthoDB" id="531008at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031588">
        <property type="term" value="C:nucleotide-activated protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02859">
        <property type="entry name" value="E_set_AMPKbeta_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000562">
        <property type="entry name" value="Snf1 kinase complex beta-subunit Gal83"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.250.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032640">
        <property type="entry name" value="AMPK1_CBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006828">
        <property type="entry name" value="ASC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037256">
        <property type="entry name" value="ASC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050827">
        <property type="entry name" value="CRP1_MDG1_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10343">
        <property type="entry name" value="5'-AMP-ACTIVATED PROTEIN KINASE , BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10343:SF84">
        <property type="entry name" value="5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16561">
        <property type="entry name" value="AMPK1_CBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04739">
        <property type="entry name" value="AMPKBI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01010">
        <property type="entry name" value="AMPKBI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160219">
        <property type="entry name" value="AMPKBI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Association with the SNF1 complex (ASC)" evidence="5">
        <location>
            <begin position="349"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="326"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="21"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="53"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="81"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="96"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="340"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ28107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="479" mass="51892" checksum="3531556D88811A12" modified="2011-01-11" version="1">MGNNPSSSKSTTPVSSQDSPKHHHHHHHHPKRESKHIIPPRSAERVAAPPEPSLTQAQGSTITKGPKPLQSIPISNFTTGSPSSNSSNSAPQPKPPEAKHIVRDAPSKPVNVPAAAAATTESSSLRSHYSAHMIEPALVGNSSVNDMSYLTRPPRMPLPIEEEIHTPGSPIIAPSDTNDGSVPEVEILEDGMTRKSSALSTNTAEDEDNEELIVDKTRPTVPTRLEWRKGGGKIYVTGTIFQWNRKHRLHPVEGQPGVFAATIHILPGTHHIRFLVDGIMQTSPDLPTTVDFGNNLVNFIEVSADDLPAKAPVEPGKDGVATAATVDKGALKTSGSQTDDQPKPPRGREVPSPSQYFQQIPKYLVDFDQPEDSPAYQYAVTAIEKLPTPPSLPGFLGKPILNAAVLMKDDNSVLNMPNHTVLNHLATSSIKNNILAVSATTRYKNKASHPLLVTQFFTHTKYSTSRQSYISPPQQKSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBE2</accession>
    <name>E3QBE2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 17">Delta-aminolevulinic acid dehydratase</fullName>
            <ecNumber evidence="5 17">4.2.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">GLRG_03425</name>
    </gene>
    <organism evidence="21">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 17">
            <text>2 5-aminolevulinate = porphobilinogen + 2 H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58126"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="4.2.1.24"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 17">Homooctamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 18">Belongs to the ALAD family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.24" evidence="5 17"/>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092301.1">
        <property type="nucleotide sequence ID" value="XM_008094110.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBE2"/>
    <dbReference type="STRING" id="645133.E3QBE2"/>
    <dbReference type="GeneID" id="24408790"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03425"/>
    <dbReference type="eggNOG" id="KOG2794">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035731_0_1_1"/>
    <dbReference type="OrthoDB" id="1530at2759"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00318"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004655">
        <property type="term" value="F:porphobilinogen synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04824">
        <property type="entry name" value="eu_ALAD_PBGS_cysteine_rich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000048">
        <property type="entry name" value="Delta-aminolevulinic acid dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001731">
        <property type="entry name" value="ALAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030656">
        <property type="entry name" value="ALAD_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006762">
        <property type="entry name" value="PRK09283.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11458">
        <property type="entry name" value="DELTA-AMINOLEVULINIC ACID DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11458:SF0">
        <property type="entry name" value="DELTA-AMINOLEVULINIC ACID DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00490">
        <property type="entry name" value="ALAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001415">
        <property type="entry name" value="Porphbilin_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00144">
        <property type="entry name" value="DALDHYDRTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01004">
        <property type="entry name" value="ALAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00169">
        <property type="entry name" value="D_ALA_DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="10 17" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 17" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 16" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="14">
        <location>
            <position position="253"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="14">
        <location>
            <position position="306"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>5-aminolevulinate</name>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>5-aminolevulinate</name>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="333"/>
        </location>
        <ligand>
            <name>5-aminolevulinate</name>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="372"/>
        </location>
        <ligand>
            <name>5-aminolevulinate</name>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001415-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR001415-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR001415-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU000515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU004161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EFQ28281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="383" mass="41561" checksum="A4D723397A3F4AA5" modified="2011-01-11" version="1">MSFSSLVQDLTLRDSGVPRRSRGDQSVSTMDDGRSQISRAMSYASTAATSVSISGDISSQLHGGYFHPLARSWQAERQLTKSMLIYPLFVSDQDDEEALIPSLPGQYRRGINKTMAYVETLVRKGLRSVMLFGVPVRPGVKDALGTAADDPEGPVIRSIRAIRQRFPQLFICADVCLCEYTSHGHCGILRDDGSLNNQLSVDRISDVAIAYALAGAHCVAPSDMNDGRIRAIKLKLIEEGIAHKTVLMSYSAKFSGCLYGPFRDAAGSAPSFGDRKCYQLPPGGRGLARRAIVRDIGEGADIIMVKPASQYLDIISDAKELGKDMPVAAYQVSGEFAMIHAAAKSGVFDLKQMAFESTEGILRAGATIVISYFTPDFLDWLST</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBR3</accession>
    <name>E3QBR3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">beta-glucosidase</fullName>
            <ecNumber evidence="10">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_03546</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="10"/>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092422.1">
        <property type="nucleotide sequence ID" value="XM_008094231.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBR3"/>
    <dbReference type="STRING" id="645133.E3QBR3"/>
    <dbReference type="GeneID" id="24408911"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03546"/>
    <dbReference type="eggNOG" id="ENOG502QR4D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004542_4_0_1"/>
    <dbReference type="OrthoDB" id="47059at2759"/>
    <dbReference type="UniPathway" id="UPA00696"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.300:FF:000006">
        <property type="entry name" value="Beta-glucosidase H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000495">
        <property type="entry name" value="Periplasmic beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037524">
        <property type="entry name" value="PA14/GLEYA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011658">
        <property type="entry name" value="PA14_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF27">
        <property type="entry name" value="BETA-GLUCOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07691">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00758">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51820">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 10 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PA14" evidence="11">
        <location>
            <begin position="395"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ28402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="833" mass="90981" checksum="784B5735E4D91041" modified="2011-01-11" version="1">MADFDVEEVLKKLTVSEKVDLLAGIDFWHTKALPNHNIPSIRLSDGPNGVRGTKFFNGIKAACFPCGTALGATFNTELLEEAGRKMGEEAKLKGAHCILGPTINMQRSPLGGRGFESIGEDPVLAGLGSAAIVRGIESTGIQATPKHFVCNDQEHRRNAVHSIVTERALREIYALPFQLTFRDSTPGALMTAYNGVNGTFCSENSDLLDKLVRKEWGWDGMIMSDWYGTYSTTEAANAGLDLEMPGPPRFRGEPLKFNVSTDKVRQHVLDERARAMLKFIKKAVATGIPEGAPEKTGDTPETAELLRRIGGESIVLLKNDDNVLPLKKDKKTVVIGPNAKIATYHGGGSAALAAYYAVTPFDGISKKLQSPPEYTEGAYSHKLLPLLGNVCKSADGKHGMTMRAYNEPPTDRHREFVDELVLTKTELLLVDYYNPKLKSNLWYADFEGSFVAEEDCAYELGLIVCGTANLFVNGKLVIDNSTSQRQGDAFFGAATVEEKGRVELKKGETYTFKVEFASAPSSKLQGGNVIFGGGALRIGGCKVIDNKAEIAKAAALAKDADQVIICSGLNADWETEGNDRADMDLPGYLNKLISAVAQANPNTVVVNQSGTPVRMPWAKDVKALVQAWYGGNETGNAIADVLFGDVNPSAKLSLSFPERVQDNPAYLNYRTEASRTLYGEDVYIGYRYYEYIDRPVLFPFGHGLSYTSFSFSGLKVTEKDGKIAVNVNVKNTGKLQGAEVVQVYIAPKQKAKVNRPLKELKGFAKVFLAPEESKSVTVDIETKYAASYFDEERHQWCAEEGEYEVIVSDSSVLTDKAAKGSFQVGETFWWSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBY5</accession>
    <name>E3QBY5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycosyltransferase family 25</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_03364</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 25 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092240.1">
        <property type="nucleotide sequence ID" value="XM_008094049.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBY5"/>
    <dbReference type="STRING" id="645133.E3QBY5"/>
    <dbReference type="GeneID" id="24408729"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03364"/>
    <dbReference type="eggNOG" id="KOG4179">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032992_0_0_1"/>
    <dbReference type="OrthoDB" id="47375at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06532">
        <property type="entry name" value="Glyco_transf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050757">
        <property type="entry name" value="Collagen_mod_GT25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002654">
        <property type="entry name" value="Glyco_trans_25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10730:SF53">
        <property type="entry name" value="GLYCOSYLTRANSFERASE 25 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10730">
        <property type="entry name" value="PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01755">
        <property type="entry name" value="Glyco_transf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 25" evidence="6">
        <location>
            <begin position="107"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ28220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="410" mass="45365" checksum="6CBBDC1E0505F6C0" modified="2011-01-11" version="1">MQSGSSFSASRESRDLPRSSSASQSSIEAGYDTQSRSFLNQNVFKNARHYVPTRLLSNRRLAIAFGCAIFLVILIVATTTGQQKRAIVFELNAATNRTLGFGSIEMINLPIRQDKADAATVQAFLSGIDINIMEGVNGSRLGEVGMPPSSIPDTEPGLSGGEKGCWRSHANAWRSMLRANRGTVLIMEDDVTWDINIKEVMRLASSNLAVLLNGTRMFDIGQSQSKVRNALFDPWYSDRWDLITFGQCGDGDGWKSERIKYDDPYTNGKQSEYFGVGLKGGRRMVRRAGGMTCTGAYAVSARGAAKLLLRSNFDLNLPVDVIMNDMIGNGQLHAYSIWPPPVVQWRYRDKLGMWGSMGSDIRVEHKDQDRSGWQEAHKKHDVWQLKGDTTGLKSPAIKSAWGTLIGLDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QC35</accession>
    <name>E3QC35_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_03414</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092290.1">
        <property type="nucleotide sequence ID" value="XM_008094099.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QC35"/>
    <dbReference type="GeneID" id="24408779"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03414"/>
    <dbReference type="eggNOG" id="ENOG502SCZR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_162820_0_0_1"/>
    <dbReference type="OrthoDB" id="5355526at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ28270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="72" mass="8237" checksum="A10DB948D400CC4C" modified="2011-01-11" version="1">MCYQIVELYSACRCLYYQHAIDRCAGYGRPGHSIQKRTILVGYACNAHSQGHGQYASQYTYSDSGYQSSHYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QC82</accession>
    <name>E3QC82_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_03614</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092490.1">
        <property type="nucleotide sequence ID" value="XM_008094299.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QC82"/>
    <dbReference type="STRING" id="645133.E3QC82"/>
    <dbReference type="GeneID" id="24408979"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03614"/>
    <dbReference type="eggNOG" id="ENOG502SXJS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112122_1_0_1"/>
    <dbReference type="OrthoDB" id="4851721at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180298" evidence="1">
        <location>
            <begin position="18"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ28470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="151" mass="13991" checksum="83833E9287A7B098" modified="2011-01-11" version="1">MRFTAATVFALVSLAAAQETTTTPAIPGASELSSIFNSVTSGLASEASGIASSAAGAASSAAADASSAVNAITSSAGAQQSSLSAALSSATDASASASLSRAIESASSEAASRIESATGTTTAPDAAGGAQQTAAVALGALFGGAALVANM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCA9</accession>
    <name>E3QCA9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Chloride channel protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_03641</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the chloride channel (TC 2.A.49) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092517.1">
        <property type="nucleotide sequence ID" value="XM_008094326.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCA9"/>
    <dbReference type="STRING" id="645133.E3QCA9"/>
    <dbReference type="GeneID" id="24409006"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03641"/>
    <dbReference type="eggNOG" id="KOG0475">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003181_2_2_1"/>
    <dbReference type="OrthoDB" id="44789at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005247">
        <property type="term" value="F:voltage-gated chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04591">
        <property type="entry name" value="CBS_pair_voltage-gated_CLC_euk_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03684">
        <property type="entry name" value="ClC_3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3080.10:FF:000011">
        <property type="entry name" value="Chloride channel protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.580.10:FF:000119">
        <property type="entry name" value="Chloride channel protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3080.10">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="ClC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45711">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45711:SF6">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00762">
        <property type="entry name" value="CLCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7 9" id="KW-0868">Chloride</keyword>
    <keyword evidence="5 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="262"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="307"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="336"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="364"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="438"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="474"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="535"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="608"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="637"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="11">
        <location>
            <begin position="693"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="840"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="79"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="855"/>
            <end position="877"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ28497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="887" mass="97176" checksum="D52BC7B69074202A" modified="2011-01-11" version="1">MDGRVHNDSSASSSSRPLNNGNNSDPTDRDELDFWSDDEDVADVLIEDPIHDDLEEPLSFKRKQKQAVSSASGRFLSAFTGSRPGTASPHSSPRARTPTQDPNRSPRRADVHGTANQSTKDGAPLDWYAEGPGRRVRYEDLTAIDWIFEYTKERQRLRVLHSSAHGLLGLLKQLLDASEIWVILILTGMAVGTVAAGIDITTDWLGDLKTGYCASGPEGGAFYLNKNFCCWGYHEISKCSGWTPWAQALGISSAVGKWFIEYFFFLIFSVCLASAAAVLVKEYAIYAKHSGIPEIKTVLGGFVIRRFLGSWTLITKSLGLCLAVGSGMWLGKEGPLVHVACCCANLFIKLFSNINDNEARKREVLSAAAASGISVAFGSPIGGVLFSLEQLSYYFPDKTMWQSFVCAMTAAVVLQAFDPFRTGQLVMYQVKFSTSWHGFELIPFILLGILGGIYGGLFIKANMAVARWKKNTPWLPGPITQVAAIALLTALINYPNHYMKFQTSELVSNLFVECSKYVDDEIGLCKTGAASTPTIVLLIFGAILGFFLATVTFGLQLPAGIILPSMAIGALTGRAVGIIMEIWVTNHPAFFAFAACEPDVPCVTPGTYAIIGAAATLAGVTRMTVSIVVIMFELTGALTYVLPIMIAVMISKWVGDAFSRKGIYEAWIHFNKYPFLDNSEEMVIPDIPASQIMTRIEDLVVLTATGHTIGSLQNILNTHPYRGFPVISDPREALLLGYISRAELSYNLQMCSQPPRSLPPETEAFFSHQPLADPRTTLDLRPWMDQTPITMASRSNLHLAVNYFQKLGLRYVLFSDRGALQGLLTKKDVWYVLNGADETRQSSGLSRDMGVETGLTREDAGGEQRGLLRGDGHEERISPANDQEPIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCL4</accession>
    <name>E3QCL4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_03746</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092622.1">
        <property type="nucleotide sequence ID" value="XM_008094431.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCL4"/>
    <dbReference type="GeneID" id="24409111"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03746"/>
    <dbReference type="HOGENOM" id="CLU_2391853_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ28602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="94" mass="10323" checksum="6182FA2E038D69E6" modified="2011-01-11" version="1" fragment="single">CLAWLVRLRGATEHKWRVLAETEASSFGVGLEASHAFERAASMDLTALGRKLDSRVYTVRQLGRVVTTGSGCKRCPTTCMRSARPLFNIPRGSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCQ1</accession>
    <name>E3QCQ1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">GPI ethanolamine phosphate transferase 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_03783</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI second mannose.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Endoplasmic reticulum membrane</location>
            <topology evidence="1 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the PIGG/PIGN/PIGO family. PIGG subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092659.1">
        <property type="nucleotide sequence ID" value="XM_008094468.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCQ1"/>
    <dbReference type="STRING" id="645133.E3QCQ1"/>
    <dbReference type="GeneID" id="24409148"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03783"/>
    <dbReference type="eggNOG" id="KOG2125">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004770_0_0_1"/>
    <dbReference type="OrthoDB" id="272139at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="PHI-base" id="PHI:12181"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051267">
        <property type="term" value="F:CP2 mannose-ethanolamine phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16024">
        <property type="entry name" value="GPI_EPT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002591">
        <property type="entry name" value="Phosphodiest/P_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037674">
        <property type="entry name" value="PIG-G_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039527">
        <property type="entry name" value="PIGG/GPI7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045687">
        <property type="entry name" value="PIGG/GPI7_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23072:SF0">
        <property type="entry name" value="GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23072">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL GLYCAN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01663">
        <property type="entry name" value="Phosphodiest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19316">
        <property type="entry name" value="PIGO_PIGG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 12" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="456"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="542"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="575"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="733"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="783"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="817"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="domain" description="GPI ethanolamine phosphate transferase 2 C-terminal" evidence="13">
        <location>
            <begin position="426"/>
            <end position="845"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU367106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF19316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ28639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="846" mass="92476" checksum="4246D0B322D5EC8D" modified="2011-01-11" version="1">MSFRYGPGFLATLLTVANILIPLAIVTFATGFFPYKPVLPGLAKYETLDYGPPPAAPFDRLIFMVVDALRRLIRNGAALPFTAYARSPTVTMPRIKAITTGSIPSFLDVILNLDEADTSSTLAAQDTWLAQMKAKGAGELAMYGDDTWLKLFPGTFDRSDGTSSFFVADFTEVDNNVTRHIDTELQNDDWSTLVLHYLGLDHIGHKSGPRSSHMVPKQHEMDDIVKRIYSAMDTQSHMSSALLVLCGDHGMNDAGNHGASSPGETSPALVFISPKIKALQRNLSAPAAFKEDFSYYTMVEQSDLVPTLGALLGFPAPKNNLGAFISDFLPFWPDRNDQVQLLIRNARQILKVVTATFGPEMFDTATTSAREACAGPQDDAQELACEWHRVNDALKNMDGQAELDPIWLEAMSKWLSKAQDLMSGMASNYDMDRLHIGEAVAILATGSLVFGARLSLIPLLAIAVAYGVMMFASSYVEEEHHFWYWTTSAWLGILAIKKMQTTRAPIKTLLSLLLALTATRLIRGWNQTGQKRAGEPDIVKTFIAANPHFLWTVVSLTYLFLFVQILRQLRGLPRALAVATSATLALSAFTFKVAFTNEDAPELVTGVPATLNALIQGLSLVTRARTVFAGVAATAAYSTYLTLSNPRVEARHTSPLLHHLITLLLATQSRVTNIPLLLLFTFQLPFLASLDLGLPALSTTSLLLQYASFFAFGGTNAISSVDLSSAYNGVAGFSVIAVGVLTFIGNWAGPIYWASATNLLLLQYRSRRAGDAADGRNVFLQHVGHMTLFTACSVAFIMVACEALRTHLFVWTVFSPKYLYCMAWSIGQHLLINVVIVGLLYRLGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCT3</accession>
    <name>E3QCT3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MBOAT family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_03815</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092691.1">
        <property type="nucleotide sequence ID" value="XM_008094500.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCT3"/>
    <dbReference type="STRING" id="645133.E3QCT3"/>
    <dbReference type="GeneID" id="24409180"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03815"/>
    <dbReference type="eggNOG" id="KOG2704">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011340_5_0_1"/>
    <dbReference type="OrthoDB" id="286734at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003841">
        <property type="term" value="F:1-acylglycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047184">
        <property type="term" value="F:1-acylglycerophosphocholine O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046474">
        <property type="term" value="P:glycerophospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030258">
        <property type="term" value="P:lipid modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049941">
        <property type="entry name" value="LPLAT_7/PORCN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004299">
        <property type="entry name" value="MBOAT_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13906:SF4">
        <property type="entry name" value="LYSOPHOSPHOLIPID ACYLTRANSFERASE 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13906">
        <property type="entry name" value="PORCUPINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03062">
        <property type="entry name" value="MBOAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="380"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="419"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="455"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ28671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="538" mass="60672" checksum="91A7B6D38F30EDAC" modified="2011-01-11" version="1">MLPFINKPFELLASRLGASSDELKLIFSFLISYPLAGLLKRVPDARPDQKNLFIICTSTFYLVGLFDLWDGVRTLAIASIGVYSIAKYLRTSSFMPWIGFGFLMGHMSINHISRQTANNPSSVDITGAQMVLLMKLSAFCWNVADGQLPEDQLSDYQRERRLVDLPDILDYAGYVLFFPSLFAGPAFDYIDYRKWIDTTMFDLPAQVDPSKAPPVRKKRKIPRSGTPATLKAASGLGWIGLFMLLSNYYPTTYLTSPSYMDHGFLHRVWILHMSGFTARLKYYGVWCLTEGACILAGLGYNGVDPVTGKVSWNRLQNINPWGVETAQNTRAYLGNWNMNTNNWLRNYIYLRVTPRGKKPGFRASLATFGTSALWHGFYPGYYLSFILASFIQTVAKNYRRYFRPFFIDPSSGAPTSSKIYYDILSWFVTQLGMSFVVAPFNILEFSGSVQVWARVYFYVIVGTVLSMAFFASPAKQMLRKQLEQRQGKAGAKLTRTLSQDSLSGREPVLGVAADPQREINEAMEEIKAGVEARQKKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCU8</accession>
    <name>E3QCU8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_03864</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092740.1">
        <property type="nucleotide sequence ID" value="XM_008094549.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCU8"/>
    <dbReference type="STRING" id="645133.E3QCU8"/>
    <dbReference type="GeneID" id="24409229"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03864"/>
    <dbReference type="eggNOG" id="KOG1721">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056436_0_0_1"/>
    <dbReference type="OrthoDB" id="6365676at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001075">
        <property type="entry name" value="Zinc finger, C2H2-type/integrase, DNA-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF111">
        <property type="entry name" value="KRUEPPEL-LIKE FACTOR 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="132"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="165"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="189"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="196"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="244"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ28720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="297" mass="32081" checksum="B457797814E23D3B" modified="2011-01-11" version="1">MHARDATGRQVSLLNDEPTVQPMPQRISYHTANQVISQPFHPAPRSNSSSPHTPELLRSDSYDSNASSDPLSPMTPTTYDPSRVGAFPGQSIHDEYEMPPKRPAYANTSRANSYEEDSSATSPLPERPGKRYPCRYRDSHGCEKTFTTSGHASRHSKIHTAEKAVQCTFHGCQKKFTRADNMKQHLETHYKDKSRSTASAKAAARSSLGGLASSGRRSSSSSAKAAASSRPRDQPMWEGESPYGYPPGQAPLPSPAATGAWDMRGLNLPLLSRPSAARTPSSGLDALAMAVACQEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QD39</accession>
    <name>E3QD39_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Mediator of RNA polymerase II transcription subunit 16</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Mediator complex subunit 16</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MED16</name>
        <name evidence="13" type="ORF">GLRG_03955</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the Mediator complex subunit 16 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092831.1">
        <property type="nucleotide sequence ID" value="XM_008094640.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QD39"/>
    <dbReference type="STRING" id="645133.E3QD39"/>
    <dbReference type="GeneID" id="24409320"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03955"/>
    <dbReference type="eggNOG" id="ENOG502QQU3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007624_1_0_1"/>
    <dbReference type="OrthoDB" id="4139168at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048338">
        <property type="entry name" value="Mediator_Med16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048339">
        <property type="entry name" value="Mediator_Med16_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021665">
        <property type="entry name" value="Mediator_Med16_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13224:SF6">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13224">
        <property type="entry name" value="THYROID HORMONE RECEPTOR-ASSOCIATED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20719">
        <property type="entry name" value="Med16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11635">
        <property type="entry name" value="Med16_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0010">Activator</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Mediator complex subunit Med16 N-terminal" evidence="11">
        <location>
            <begin position="151"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="Mediator complex subunit 16 C-terminal" evidence="12">
        <location>
            <begin position="859"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="389"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF11635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF20719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ28811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="968" mass="107274" checksum="A99A16D5C5FA2F71" modified="2011-01-11" version="1">MPLILESGMNGPMQVDQLDVDDLFGDGVGLSLHTARPPTKHLRQRIDELRTRGCCQGVAWSKSGAIASISPDGKTLEARFLRSHPDDGNWGLSEPTKVDLISINASSPIVHLAWASTANPELAVIDATGRVAILTYSITLNRPFATRKWDHDPSDDLHAIVGSYWLPLAPQAKQYYVSHGPAVKDGNQYRYESSFVHAYGPWHPNTSKSALLCVTTNGHLKMFWAQNNNKIEETTLELESVNSSDDLITHAALHSDKSNLWIALATTSKQLRLVRVGINWGLPQSQSDNKPPPGSQALNPTLQEKHVAITSWLPSGSSTTPIDSAANQLTHLEILPSTLDHTGQGWAPLIILAVRTYLPTPNTPYQETQSIIDKWEVLNDQAQSLHPAFEQLGSRRNSTGAGPAPTSRLKKHDPVIVNKVIIGVHTLQFGRVICLAFSDGSVEYRDRFTLQEIYNEINLDRVMTLNQVGFTFQDESPCLQMAFSPTNCSVVKIQDDGKAKWSKLHYPLGDIGNSSQDAPYAATLAALTVAASTATFNNINYDDILAVARPYADKKRFTFDWINEIVRMLKVPVDYSEDTHHDSLVRNSSLQMCLSILNHLGYKGMFQPRSFGSKFAMLALNARNVVILITIASNTPVNIREKLSPLDEHEVVEALAGCAKWSLDLLSWLTDSLFALLDDPQFLALLTPQRFSEMSTYLQSRSDVSLHLLLCSSTRGFLSAVCRRILHLEILSNRAIEFYERRAAMQNATDPSAQAKGPHVVLYKAYQKMQRVTSGSLIKVQEFDRLLTVLNNDIRSAYQSSLASLAAKNPPGPGGQKAIDAQIKNAQIHCELNMLLASSPPPAFHHVLLKFFNSDLKAYRAQADPSKLFFADFDLLEIDDDRRTLATRKAKGRYIDVFKRIELAAPPARGTKEGDEAKMAQWRRCVRCSAIMEDVFGSRPGFTFVLAQQRKCSCGGHWGLLPKGALII</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>E3QD78</accession>
    <name>E3QD78_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_03994</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092870.1">
        <property type="nucleotide sequence ID" value="XM_008094679.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QD78"/>
    <dbReference type="GeneID" id="24409359"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03994"/>
    <dbReference type="HOGENOM" id="CLU_2126884_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ28850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="114" mass="12773" checksum="B57F2414FCB19AB0" modified="2011-01-11" version="1" fragment="single">MTPQSFVVGRRAVDTPYNKREEDLMYGIRSCVRVWTWLSTIRGNESCFLKLSAALVACRQHPCACRSVLQPSAAAGVLQPIRDCSLFVLAIGREKLPLSARKRESSLFLLSFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QD85</accession>
    <name>E3QD85_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04001</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092877.1">
        <property type="nucleotide sequence ID" value="XM_008094686.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QD85"/>
    <dbReference type="STRING" id="645133.E3QD85"/>
    <dbReference type="GeneID" id="24409366"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04001"/>
    <dbReference type="HOGENOM" id="CLU_2037888_0_0_1"/>
    <dbReference type="OrthoDB" id="5415512at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ28857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="121" mass="13673" checksum="A1C50AC1D321BF42" modified="2011-01-11" version="1">MTLIMTLDSTQRFLRKIKKPPRTIEAFIKAARILTFPVSVSPSPATYILQTDKSRPRFPRRFPGRSADQGPDIEHNFPNDIPLPSTGCAMEIPDDMSDSNVHNLLIPGYDDYVPWRKTGST</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDH5</accession>
    <name>E3QDH5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peptide hydrolase</fullName>
            <ecNumber evidence="7">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_04091</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M28 family. M28B subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="7"/>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092967.1">
        <property type="nucleotide sequence ID" value="XM_008094776.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDH5"/>
    <dbReference type="STRING" id="645133.E3QDH5"/>
    <dbReference type="GeneID" id="24409456"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04091"/>
    <dbReference type="eggNOG" id="KOG2195">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024336_1_1_1"/>
    <dbReference type="OrthoDB" id="10013407at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04816">
        <property type="entry name" value="PA_SaNapH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF26">
        <property type="entry name" value="PEPTIDASE M28 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="6 7" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005127987" description="Peptide hydrolase" evidence="7">
        <location>
            <begin position="20"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="8">
        <location>
            <begin position="127"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="9">
        <location>
            <begin position="247"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ28947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="498" mass="53276" checksum="8DF6F68004DFD17D" modified="2011-01-11" version="1">MKLCKSAAALLSLASGIVATNTTCRPKIDSEKLQADLTTENLMANLKALNEIAFVNGGNRAFGLSGYAASVDYVWNRVSNISGTKAWKQDFPATFGQVISIDFNIEGESIYVFGLTYSPSTSEEGITAEVILGPEGAAGCDAANYKGLNVQDKIVLVQRYRCPTGGTLAGRVRPAAAAGAAAVIVYHDVTTNATAGSLSAPDPEGFVPAGFINLADGLRIKERIDTGETIVAHFQQTQIVEERITQNVLVETEEGDPHNVIMLGAHLDSVQAGPGINDDGSGTSLLIELFLALTKYRTKNQVRFAWWGAEENGLLGSKYYCSNLPTYDVDNLLVYLNFDMVAKGFFGVADTDGSTHGTAGPAGSDVVEHIYEAYFESQGLEVTPAVLTNGSDYASFWKILHKPFGFLHTGTAVAQDPCYHQACDTIDNPDPNTITVNARAAAHMLTALSLNGTELIPKTPANATMLMHLQSRGLENDIIHIEELEALGERHLGCGHDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDQ3</accession>
    <name>E3QDQ3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">C2 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_04135</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ28991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093011.1">
        <property type="nucleotide sequence ID" value="XM_008094820.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDQ3"/>
    <dbReference type="STRING" id="645133.E3QDQ3"/>
    <dbReference type="GeneID" id="24409500"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04135"/>
    <dbReference type="eggNOG" id="ENOG502RDJ2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008050_0_0_1"/>
    <dbReference type="OrthoDB" id="270970at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08681">
        <property type="entry name" value="C2_fungal_Inn1p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037791">
        <property type="entry name" value="C2_fungal_Inn1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052981">
        <property type="entry name" value="Ingression_C2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47052">
        <property type="entry name" value="CONSERVED SERINE PROLINE-RICH PROTEIN (AFU_ORTHOLOGUE AFUA_2G01790)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47052:SF3">
        <property type="entry name" value="INGRESSION PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="2">
        <location>
            <begin position="14"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="406"/>
            <end position="1123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="268"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="432"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="503"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="566"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="606"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="658"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="668"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="734"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="775"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="948"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="988"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1018"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1055"/>
            <end position="1066"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ28991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1163" mass="129069" checksum="7633F0344F6097D3" modified="2011-01-11" version="1">METAKLSKVHPLNGMHTAGIFADPSIDGPLIGTLVAIVDRAKNLPNRKTIGKQDPYCAARLGKEAKRTTTDIRGGQTPRWDQELRFPVHDSPDYYQLKVSVFNDDKKTDLIGETWIDLRDIIVPGGGQNDIWRNLTFKGKYAGEVRMEITYYDQRPKPEKPIAKPKPVEAEPTDYHHGTIPRKQIKRRPLPSDPFTGEAPAAPSPDQALTPPRTGGPRGPKEMSTPTPTAQEASLSGSRPMPKGPKQLQPAQVPTKSPLQAIEYNTNAAPLAQPTQQDLPAQPLQAALPPHSTEVTPQHTPRHERYESPTAQYDDRDYSPRYSSQEIVNQAHYRQGSEPPRELLYLEDQRQEPPADDDRPPPPPAHRSRGNSQDMVVRAAYDTPPKSANAMRQDVLRNEAHRMSFSSTAYPGRPTYRGFDSAPAVTNALPAPEDHHHHELTSSRHHSYDAHAEYRSMQPTVEDVPELPNTSANPHQRRISRAPPYEETGYGQEHNQLPPPPQQSQQLQLQQQQQLQQQQQLQYQQQQQQQQQQQQQQFQQQQQQQFQQQQQQQFQQQQQQQQQQQAMQLSQRRNSYTPQYDEMGYDQGYDQVPSPAPLNIGGRGSAGSSRQRGASPQPGYGRGDEMSQAGRYSTSPHPEYQPRGDELVFAGRGGTSPGHYSTSPQPEHQQDYQPRGDELVLAGRGDVSPGHYSTSPQPYVRGDEMARRQQVSPIATRDFAPSPMEGSPYHSHFRSQTQFTSQRSELGGTEVTAHSMPAVPASLVPGTDPTISQEVSDRIYDERRQQRRYTDQSMAIQHRGRQHSEPVGYDGSYTNQTYVPPGYNSRASAYGAPPPDMNRGRGPSPNPMRGRGASPNPMMARGSSPNPMTARDVSPNPMRRGASPQPPPQHMRSRGISPNPHTQHTIKRKSVSPAPPPSEHRRLSGIPFGPDSYDMLNPAVSTTNSDISRPDPDEKIITHDGREIDPSDHLPMDTWAPEPEPKGPKTPASASTRSRASTADAQPLPTSGRRQLRIAARPQSQASPVTYSSDPYHVPGTPPNMSSAGRNRLQKKTQRMSALPSTSPAGSSPLAPISSHNYQDNGGDFTPPRLPRASTWDYPSENHAPQYGSSPGRNYGGGGAPPIPAKVPLPMMSGANGDNEWALMQEMSRIDIGAGRSRRHRHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QE30</accession>
    <name>E3QE30_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Meiotic recombination protein DMC1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_04262</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RRP7 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093138.1">
        <property type="nucleotide sequence ID" value="XM_008094947.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QE30"/>
    <dbReference type="STRING" id="645133.E3QE30"/>
    <dbReference type="GeneID" id="24409627"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04262"/>
    <dbReference type="eggNOG" id="KOG4008">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036234_1_1_1"/>
    <dbReference type="OrthoDB" id="5390at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032545">
        <property type="term" value="C:CURI complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034456">
        <property type="term" value="C:UTP-C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12293">
        <property type="entry name" value="dRRM_Rrp7p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12950">
        <property type="entry name" value="RRP7_Rrp7p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040447">
        <property type="entry name" value="RRM_Rrp7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040446">
        <property type="entry name" value="RRP7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024326">
        <property type="entry name" value="RRP7_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13191">
        <property type="entry name" value="RIBOSOMAL RNA PROCESSING PROTEIN 7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13191:SF0">
        <property type="entry name" value="RIBOSOMAL RNA-PROCESSING PROTEIN 7 HOMOLOG A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17799">
        <property type="entry name" value="RRM_Rrp7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12923">
        <property type="entry name" value="RRP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rrp7 RRM-like N-terminal" evidence="3">
        <location>
            <begin position="10"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal RNA-processing protein 7 C-terminal" evidence="2">
        <location>
            <begin position="193"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ29118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="313" mass="35591" checksum="2255BEBCC4D9A919" modified="2011-01-11" version="1">MSPTESQGDGFVILPVKLPALPSCPITALHEIRVRRNASKIPTEIDDRSLFLKNVPVDSTEAHFRQVFAALVGPGRFESIAFENERKTTTAIDPAQAVKVTGFGKKRKRDEQEAEERAKEEEVARLPEIWTRRLRKSGSSAIVLLADEKSVELVMKAIKKTSKSKKFPVWGEGVSSDLSELGSQWITAHMQLTRCDKAATQKSVHAFFNVFNRKEKEAAEMAKRLRNEPDEDGFVTVVRGGRVAPANKNEAEEARQKMVDKAEKKKSETTDFYRFQLRERRKAEQAALMKRFDEDRKKVEAMKEKRGKFRPET</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEK2</accession>
    <name>E3QEK2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Calmodulin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_04452</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093328.1">
        <property type="nucleotide sequence ID" value="XM_008095137.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEK2"/>
    <dbReference type="STRING" id="645133.E3QEK2"/>
    <dbReference type="GeneID" id="24409817"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04452"/>
    <dbReference type="eggNOG" id="KOG0027">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061288_2_0_1"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016460">
        <property type="term" value="C:myosin II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000001">
        <property type="entry name" value="Calmodulin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050230">
        <property type="entry name" value="CALM/Myosin/TropC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF0">
        <property type="entry name" value="CALMODULIN LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="10"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="46"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="87"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="123"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00020786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ29308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="159" mass="17512" checksum="2781D65BD7C6131F" modified="2011-01-11" version="1">MAPPYGLTEEEYNDYKAVFSVFDRDGTGAINAEEFQIAMKSLGLNPSIKEVNELIAEVDPNNDGGIDFNEFLQLMSEAPAPSSKDSDTNKELVAAFKVFDKDNSGSVSPSELRQVLLSLGQRATDEEIEEMIRHADLDGNGSIDYQEFVQLMAPKDGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEN4</accession>
    <name>E3QEN4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcription factor Pcc1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04484</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CTAG/PCC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093360.1">
        <property type="nucleotide sequence ID" value="XM_008095169.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEN4"/>
    <dbReference type="GeneID" id="24409849"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04484"/>
    <dbReference type="eggNOG" id="ENOG502SBSA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_113770_3_1_1"/>
    <dbReference type="OrthoDB" id="10025739at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000408">
        <property type="term" value="C:EKC/KEOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070525">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.310.50:FF:000011">
        <property type="entry name" value="Transcription factor Pcc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.50">
        <property type="entry name" value="Alpha-D-phosphohexomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015419">
        <property type="entry name" value="CTAG/Pcc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31283">
        <property type="entry name" value="EKC/KEOPS COMPLEX SUBUNIT PCC1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31283:SF5">
        <property type="entry name" value="EKC_KEOPS COMPLEX SUBUNIT LAGE3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09341">
        <property type="entry name" value="Pcc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="118" mass="13025" checksum="D2BA7EDF5DDA745C" modified="2011-01-11" version="1">MAVNNNTTTTTTTTTDDEFPCSLTIDVPFPTPRLASVAHRALAVDQELSPLVRRTFFVDDDDSAAAAEAASVLHVYYKATTNRMLRVAVNGLMESLNLVVEVMEELDVDVLEHNRDNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEW1</accession>
    <name>E3QEW1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ppx/GppA phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_04561</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093437.1">
        <property type="nucleotide sequence ID" value="XM_008095246.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEW1"/>
    <dbReference type="GeneID" id="24409926"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04561"/>
    <dbReference type="eggNOG" id="ENOG502QRXN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033165_0_0_1"/>
    <dbReference type="OrthoDB" id="2014654at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000191">
        <property type="entry name" value="Retrograde regulation protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.150">
        <property type="entry name" value="Exopolyphosphatase. Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050273">
        <property type="entry name" value="GppA/Ppx_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003695">
        <property type="entry name" value="Ppx_GppA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057512">
        <property type="entry name" value="RTG2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30005">
        <property type="entry name" value="EXOPOLYPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30005:SF0">
        <property type="entry name" value="RETROGRADE REGULATION PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02541">
        <property type="entry name" value="Ppx-GppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23566">
        <property type="entry name" value="RTG2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ppx/GppA phosphatase N-terminal" evidence="1">
        <location>
            <begin position="54"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="RTG2 C-terminal" evidence="2">
        <location>
            <begin position="418"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ29417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="622" mass="66923" checksum="7CDCB7CDCFD7D796" modified="2011-01-11" version="1">MASSSDIITLDNFEQLLPRWDPAGTNHLYALVDMGSNGIRFSISDLTPPQTRLLRPIYRERAGISLFDALNVSPGAGSEPMMFPAETIAQVARTLARFRRIAVSYGVPPAHFSVLATEAMRRAANAREMLTAIREAADIGVHVLAPEVETLFGAVMGSRSAFVDISRGGLFLDLGGGSVQMTWVDTRLPDYEIAAALAGESMPFGAARLIRVLEGQPEEVRAQEKQRLNASMQSAFAKLCDKFPVLAQAKAEHEASATAAPTTNGAGTSAGPVAGGIDAYLCGGGFRGYGCMLQHNDPIQPYPLPSVGTYTVTGDFFKQTEKMRRVNSEHEGKIYGMSKRRRQQFPAIIEVVEAFIRTVPHLRTVTFCGGSNRDGALLMKLPKSVRESNPLEALAGFPIQGHEDAGGAGGGKGDMAVAQAVLRTLYGAVPVNVDISRTPTVFSLGLGPLFARQVWIHQGEDDDANASYALHEAVTRDPSAPGLTHLARAVLGLTTCARWGSNLGPIDVQLYGNLKGLVAEARQESVFWAEYLGAVAAVMVDLVPAWPKSVEELESTLRFEATQTVDPEKKRASIELTVHVTAGAAVGIDPEDVKGRLSYVGKKRKDGTRPDKKVTVRIQEMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFM3</accession>
    <name>E3QFM3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Caleosin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_04805</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the caleosin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093681.1">
        <property type="nucleotide sequence ID" value="XM_008095490.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFM3"/>
    <dbReference type="STRING" id="645133.E3QFM3"/>
    <dbReference type="GeneID" id="24410170"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04805"/>
    <dbReference type="eggNOG" id="ENOG502QQD0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062049_0_0_1"/>
    <dbReference type="OrthoDB" id="640742at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007736">
        <property type="entry name" value="Caleosin-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31495:SF0">
        <property type="entry name" value="BINDING PROTEIN CALEOSIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G13750)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31495">
        <property type="entry name" value="PEROXYGENASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05042">
        <property type="entry name" value="Caleosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ29661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="305" mass="34331" checksum="5A8067DF22F8AE65" modified="2011-01-11" version="1">MAHIDPPDYNMDQLSNGYAPESKPSKKALRADRKVKSVSKGDGPDFATAVPMCPITYRRPPAVNAGKAIDSPGVAHANFAPSVDKPHGSVEYSEKYNNYTVLQQHVMFWDRNNDGVITPIDVWVGFRDLGFNLATCLLAATVIPFAFSYGTVMQYSYIPDPFFRLYVGGMHKAKHGSDSGVYDSEGRFVPQRFEDVFANCSARQDDTLTLGEVFGLMSRNRCAVDPFGWSASFFEWVTTWMLLAKDGKIHKEDLRRVYDGSLFWEIRDKRHSGKGWHQGWGIGGDWFLGDRPRLNPNDLRTNVES</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QH74</accession>
    <name>E3QH74_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">glucan 1,3-beta-glucosidase</fullName>
            <ecNumber evidence="14">3.2.1.58</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Exo-1,3-beta-glucanase D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">GLRG_05380</name>
    </gene>
    <organism evidence="20">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Glucosidase involved in the degradation of cellulosic biomass. Active on lichenan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>Successive hydrolysis of beta-D-glucose units from the non-reducing ends of (1-&gt;3)-beta-D-glucans, releasing alpha-glucose.</text>
            <dbReference type="EC" id="3.2.1.58"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.58" evidence="14"/>
    <dbReference type="EMBL" id="GG697348">
        <property type="protein sequence ID" value="EFQ30236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094256.1">
        <property type="nucleotide sequence ID" value="XM_008096065.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QH74"/>
    <dbReference type="STRING" id="645133.E3QH74"/>
    <dbReference type="GeneID" id="24410745"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05380"/>
    <dbReference type="eggNOG" id="ENOG502QRG8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004624_4_2_1"/>
    <dbReference type="OrthoDB" id="62120at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004338">
        <property type="term" value="F:glucan exo-1,3-beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000033">
        <property type="entry name" value="Glucan 1,3-beta-glucosidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050386">
        <property type="entry name" value="Glycosyl_hydrolase_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297:SF34">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297">
        <property type="entry name" value="GLUCAN ENDO-1,6-BETA-GLUCOSIDASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="18">
        <location>
            <begin position="346"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="16">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="51"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="74"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="16">
        <location>
            <begin position="130"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00036824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00037126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00038929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00041260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EFQ30236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="710" mass="80750" checksum="C3C5C9EACD89497D" modified="2011-01-11" version="1">MSPGESSRPSSHRPRDSSGRKHHHKKRRSHGQGSRRPTTDSGESRDERRSQALSADALAALNRDNTKRKKRRESRADGTRNTERDAERAAERAERRRARREQQYRDAPRERPRRAEREQDREVVYEKPRRDHKGNKRRVVSGAVMEEGRSRGHLRGGGWSSSDHSFEKEHLIVDPPQPLPKRKKLWICLGVSLVLLIIIIVVAVVVSKNNSNKSSPSKTTLGNSNKDSVPMQWRGTYLDPWSWQDTTDFNVTFTDEMVGDLPVMGLYTDWDDSKRANDKVPAINDSWGSYGSRPARGVNVGGWLNLEPFITPSLFDYDPRLGIIDEYTLCQHLGTKKTAEVLEKHYATFVTESTFKEIADAGLDHVRIPFNYWAVEVYDGDPYLFRTSWRYLLRGIEWARKYGLRVNLDVHGLPGSQNGWNHSGRQGTIGWLNGPDGATNAQRSLDMHDRLSKFFAQDRYKNIIAFYGLANEPRNVELNNADVVSWTEQAYKLVKSNGIGGIVVFGDGFMGLGNWQGKLTGYSDLALDVHQYVIFNTDQIVYTHKKKVEYACSGWTQQAEQSMDTSTGYGPTLFAEWSQADTDCAKYLTNVGWGNRWTGTYNTGNASTSILEPRCPTQDSKCDCNAANGDANGFSSDYKKFLQMFAEAQMHSFEKGWGWWYWTWDTESAPLWSYKKGLAAGILPAKAYDRDFDCSGTVPDFDDVPEYYRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHS7</accession>
    <name>E3QHS7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Ubiquitin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_05559</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the ubiquitin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697349">
        <property type="protein sequence ID" value="EFQ30415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094435.1">
        <property type="nucleotide sequence ID" value="XM_008096244.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHS7"/>
    <dbReference type="STRING" id="645133.E3QHS7"/>
    <dbReference type="GeneID" id="24410924"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05559"/>
    <dbReference type="eggNOG" id="KOG0004">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010412_2_0_1"/>
    <dbReference type="OrthoDB" id="428577at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031386">
        <property type="term" value="F:protein tag activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01803">
        <property type="entry name" value="Ubl_ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000008">
        <property type="entry name" value="Ubiquitin-40S ribosomal protein S27a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002906">
        <property type="entry name" value="Ribosomal_eS31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038582">
        <property type="entry name" value="Ribosomal_eS31_euk-type_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019954">
        <property type="entry name" value="Ubiquitin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050158">
        <property type="entry name" value="Ubiquitin_ubiquitin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10666">
        <property type="entry name" value="UBIQUITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01599">
        <property type="entry name" value="Ribosomal_S27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01402">
        <property type="entry name" value="Ribosomal_S27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00299">
        <property type="entry name" value="UBIQUITIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="9">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ30415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="154" mass="17712" checksum="2A6001FFC0CF945E" modified="2011-01-11" version="1">MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGGKKRKKKVYTTPKKIKHKRKKTKLAVLKYYKVDSDGKIERLRRECPSDTCGAGVFMAAMNDRQYCGRCHLTYVFDKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QI47</accession>
    <name>E3QI47_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioesterase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05679</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697349">
        <property type="protein sequence ID" value="EFQ30535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094555.1">
        <property type="nucleotide sequence ID" value="XM_008096364.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QI47"/>
    <dbReference type="GeneID" id="24411044"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05679"/>
    <dbReference type="eggNOG" id="ENOG502STSM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052827_4_1_1"/>
    <dbReference type="OrthoDB" id="506431at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03443">
        <property type="entry name" value="PaaI_thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052061">
        <property type="entry name" value="PTE-AB_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47260:SF6">
        <property type="entry name" value="THIOESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47260">
        <property type="entry name" value="UPF0644 PROTEIN PB2B4.06"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="1">
        <location>
            <begin position="110"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="204" mass="22482" checksum="E0BD35704DFDE4C8" modified="2011-01-11" version="1" fragment="single">SSSLHPQAVNFPTMSSNSVEVHPEYKHFASIPWCAKILAAFSSPHHVVHVSQNRTVLPTRENQYVGGTLNTPETITAWLVLHPRPQEPDWKVDELCSLITFNNGMTGFPGTAHGGVIALVLDEVTGIHIVAQRPKGAEPNKDFRTGYLNTSFYKPVPTPGTVLVRSRVTKVEGRKHYVTAQIEGEHGDVLAKAEVLYISIKNKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIR8</accession>
    <name>E3QIR8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_05900</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094776.1">
        <property type="nucleotide sequence ID" value="XM_008096585.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIR8"/>
    <dbReference type="GeneID" id="24411265"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05900"/>
    <dbReference type="eggNOG" id="ENOG502SMXQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040076_1_0_1"/>
    <dbReference type="OrthoDB" id="5343688at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="199"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ30756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="334" mass="36671" checksum="CFE03278CA37F391" modified="2011-01-11" version="1">MESQHHMGIRELNVSNWHSHNALTDTLNHAVPAIKTSAAFFTFLRANLVLNPSAMSSPVLQPTASAAQNSHRRAAPSPLATSHTLEPLDDIPPLSLEVLSTREDKAEALRLVADSIAQQRQQASSALVFHPVPLAGLALALAVAYQYSYGRQRDIGMALTLLSGIIMSYLLAIRWVTSGYLPLAEQISWSFIRPHPDASSDEEDLVLGTRFGSEIIGALVLHLEPAIPLAATTFSSKRRNKAGSFRGGKGIIRAWTTKIRYRGKGVGTDMLDEAVRIARERCGKDAEVGFALEHANSQMVLPEFFNGTFRKRERWAAKTLDGVLAERDMAKKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIZ5</accession>
    <name>E3QIZ5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05977</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
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                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
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                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
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                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
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            <dbReference type="DOI" id="10.1038/ng.2372"/>
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            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
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    </evidence>
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        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
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                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
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            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
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        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
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    <dbReference type="eggNOG" id="ENOG502S7XT">
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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    </feature>
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    </feature>
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        </location>
    </feature>
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    </evidence>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
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            <fullName evidence="2">Uncharacterized protein</fullName>
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                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
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                <person name="Proctor R.H."/>
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                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
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            <dbReference type="DOI" id="10.1038/ng.2372"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
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    </reference>
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    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06087"/>
    <dbReference type="eggNOG" id="ENOG502T24R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_990728_0_0_1"/>
    <dbReference type="OrthoDB" id="3595619at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="328" mass="35601" checksum="A07D9CB818FD8188" modified="2011-01-11" version="1">MPKRELSPILPHFDMIAPPPPARLQPNPEDDVFGPSHEPKYSPMSFHLPRKPSASPSITTASDTPPRIPPKSRARSHTSSSTEIMKERIACAMLEVDKLQHEIDLVMKRQSCYTNSRPSTSHSIALTMHGGSLPTVPALPPAAPSFAERLNPAVERPHTAPQSPGHIPHRGMIFAADDTAAFITPPPSRGRETRPLPPPLPLVLRPPLRKKKSFSRVSNWLFPSGAAGQHHQRSISSDSITNFPRPVKDREGFYQCVKAPQGRRASIGSMSTVSTSESEGGCQTVPTAWSPSSTLATRTDELPMERPSTFGKENGAGGSRGTNFAVAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJG9</accession>
    <name>E3QJG9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_06151</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ31007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095027.1">
        <property type="nucleotide sequence ID" value="XM_008096836.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJG9"/>
    <dbReference type="STRING" id="645133.E3QJG9"/>
    <dbReference type="GeneID" id="24411516"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06151"/>
    <dbReference type="eggNOG" id="ENOG502QSRP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027977_2_0_1"/>
    <dbReference type="OrthoDB" id="5135119at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009395">
        <property type="term" value="P:phospholipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007312">
        <property type="entry name" value="Phosphoesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956:SF15">
        <property type="entry name" value="ACID PHOSPHATASE PHOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956">
        <property type="entry name" value="NON-SPECIFIC PHOSPHOLIPASE C4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04185">
        <property type="entry name" value="Phosphoesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178532" evidence="3">
        <location>
            <begin position="17"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="68"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="68"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ31007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="504" mass="54822" checksum="1F59665CBE17CF35" modified="2011-01-11" version="1">MVRIISLLVAAGMAMGVPNEIAGRHGYDNDGYGNGGYWPPPSATPVSSTTDNQCTATSSVIQYTSTSTGSQYTSTSIGSQYTSTATTSTSTTSTPADLRYTETEAGAVAAAAATALTLSPVSNVTGKVFNRIMQVYLETTAYENAIADPNCQALIEQGILLSNMYGAGAPSQPNYVAPASGDIWGVNSDSFLLFNQNVSTMVDLLEDKGISWGDYNEGLPYSGFEGLTYTNPVEGNYARKHNLLVRFDSVSFDSERLAKLKNLTLFYEDLNNNRLPQWLFVTPNLSHNGHDTNITVSCNWTRSFVEPLLSNPNFNDGKTLVYITWQANGQYPLARNHVAGILLGSAIPSYLVGTSDSAYYNHYSEMSSVQANWNLHTLGRWDVGANVWNFIGSKTGDALRYWNETIAGDSFVNYYWNQSYGGVFSNGCNLPHSYVAPNLDILGGGYRTVLPAIASLWYGSGLPSYYRNIIEVNDALHPPQGFEVPIGLSTAKSIDGPIRYWPND</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJH5</accession>
    <name>E3QJH5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pentatricopeptide repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_06157</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ31013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095033.1">
        <property type="nucleotide sequence ID" value="XM_008096842.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJH5"/>
    <dbReference type="STRING" id="645133.E3QJH5"/>
    <dbReference type="GeneID" id="24411522"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06157"/>
    <dbReference type="eggNOG" id="KOG4197">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008514_0_0_1"/>
    <dbReference type="OrthoDB" id="747253at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050667">
        <property type="entry name" value="PPR-containing_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057027">
        <property type="entry name" value="TPR_mt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47939">
        <property type="entry name" value="MEMBRANE-ASSOCIATED SALT-INDUCIBLE PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47939:SF6">
        <property type="entry name" value="OS03G0168400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23276">
        <property type="entry name" value="TPR_24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Pentatricopeptide repeat-containing protein-mitochondrial" evidence="3">
        <location>
            <begin position="331"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="83"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ31013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="623" mass="69094" checksum="6049164E8B9D8508" modified="2011-01-11" version="1">MSGSRVVFDGLWRCLCPSTDAYVAARLLNSPILPRTSIATGHRRQPVRPSHTHAIRPQCRRYSTATSSTLRSEDDARAFENGEAVEGNATAGEIRHGATSTDSGPGDPNEQLRAAPLSAIYEALQVLQGQPKTFQKVTTFITHLVQSRNAELDSQLYEHLVVATADVQGSAAMLAQLFAEMKQLQLKPTTLICHAALATLAVHPDYLVRNEILAAMKQSWAEISIEGQSHNALGLLRDGQFEMALDALEAMIDKHVSIPSWVYDIFIFVFAQHGFVDEAIKLAHSKVHAGSETSLTVWYMLLDACAQTHHYEGTRYIWGRLLDTDREHLSDGTLLNVINTATRQYDYELVTSASRLITQRGSKLFAHHYEALIECYGGSGDVASALRVLCIMFKAISVAPYASTRSIYCWIKNHPESIDTALSTLTELVRSYKVPIAALNVLIEAAVDTHGYAKALEIYQNAHKYTEATPNHVTIRYILQACDDMESLKSLVAENPELALKADRNAFGKAIYEYAVSSDLDLAYKCIELYGQAPEGANGEPHSKTEAWIPKRTLLTVIRKSLDAQDERVWWLIEQAERRNIDVQSGIAKLMASFADEIKRSTGLAQEDRALGDDLEPRQHSTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJK4</accession>
    <name>E3QJK4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Calcium/proton exchanger</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_06186</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ31042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095062.1">
        <property type="nucleotide sequence ID" value="XM_008096871.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJK4"/>
    <dbReference type="STRING" id="645133.E3QJK4"/>
    <dbReference type="GeneID" id="24411551"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06186"/>
    <dbReference type="eggNOG" id="KOG1397">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008721_4_0_1"/>
    <dbReference type="OrthoDB" id="1699231at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015369">
        <property type="term" value="F:calcium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1420.30:FF:000011">
        <property type="entry name" value="Vacuolar calcium ion transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="entry name" value="NCX, central ion-binding region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004713">
        <property type="entry name" value="CaH_exchang"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503:SF20">
        <property type="entry name" value="CA(2+)_H(+) EXCHANGER, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="168"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="251"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="287"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="422"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="490"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="528"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="551"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="10">
        <location>
            <begin position="191"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="10">
        <location>
            <begin position="425"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="70"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="70"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="105"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ31042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="578" mass="62662" checksum="018274090A89AC78" modified="2011-01-11" version="1">MPSLVGSVNHFDIKRKAHGLSRRSQEQTWNPFRHVSWDNHPSKRSTWDGANLEAQREALAEDIETDEALHHVQSEPAARDSDIPRNSLRKDTRSRSGSGSGDTAYENKPEDGGVLRNRKSEAAQDEGASPEEEMEKPKKQKSGLIRHVEPKEPFTVANQLQRTLLSSYINILILAAPVGIAISYVGSVNKIAVFVVNFIAIIPLAAMLGFATEEIALRTGETLGGLLNATFGNAVELIVAILALVEGKVLIVQTSLIGSILSNLLLVMGFCFFFGGLNRPEQYFNTTVAQTAASLLFIAVASVIVPTVFDKNDHTNNPTHVAALSRGTAVILLIIYASYLFFQLKTHNAVFNEESQKVAAKPWSRGGLKEGALARGLAGTGARMAHTGVRNDGDDDRQELSRIMMQRQDEEDDEDEGPQLHFFVAVGTLTLATVLIAFCAEAMVSSIDYVTKQGGISEEFVGLILLPIVGNAAEHATAVTVAIKDKMDLAIGVAVGSSMQVALFLIPMLVIIGWGMGNDDMTLSFDQFQVAVLFVAVLLVNYLISDGKSHWLEGLQLICLYAIIATCSWWYPASGVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJT0</accession>
    <name>E3QJT0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_06262</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697353">
        <property type="protein sequence ID" value="EFQ31118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095138.1">
        <property type="nucleotide sequence ID" value="XM_008096947.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJT0"/>
    <dbReference type="STRING" id="645133.E3QJT0"/>
    <dbReference type="GeneID" id="24411627"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06262"/>
    <dbReference type="eggNOG" id="KOG4554">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099163_0_0_1"/>
    <dbReference type="OrthoDB" id="18139at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045047">
        <property type="term" value="P:protein targeting to ER"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012098">
        <property type="entry name" value="SND3_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28112">
        <property type="entry name" value="SRP-INDEPENDENT TARGETING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28112:SF1">
        <property type="entry name" value="SRP-INDEPENDENT TARGETING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10032">
        <property type="entry name" value="Pho88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF008756">
        <property type="entry name" value="P_tr_PHO88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ31118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="190" mass="20817" checksum="69CDFF5C48D5BA56" modified="2011-01-11" version="1">MVSPQITNLIIMLGMVQVSRKVPFDDPNVLNLCRAGYIASNIIIAIIYLYVQAQINKKKDMTTLKYVEPAPMGSSEEGKLVTTTIHAYDTTQLRQAFRSQAMGIAMMGFMHLYMKYTNPLLIQSIIPLKSALESNLVKIHVFGKPASGDLKRPFVAPAGFMQGLQSGPAQSDKKAIEAAERAGRGGAKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QK98</accession>
    <name>E3QK98_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_06430</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697354">
        <property type="protein sequence ID" value="EFQ31286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095306.1">
        <property type="nucleotide sequence ID" value="XM_008097115.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QK98"/>
    <dbReference type="STRING" id="645133.E3QK98"/>
    <dbReference type="GeneID" id="24411795"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06430"/>
    <dbReference type="eggNOG" id="ENOG502S1DJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031864_5_0_1"/>
    <dbReference type="OrthoDB" id="4570620at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097237">
        <property type="term" value="P:cellular response to toxic substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050097">
        <property type="entry name" value="Ferredoxin-NADP_redctase_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48105">
        <property type="entry name" value="THIOREDOXIN REDUCTASE 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00469">
        <property type="entry name" value="PNDRDTASEII"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180542" description="FAD/NAD(P)-binding domain-containing protein" evidence="4">
        <location>
            <begin position="20"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="5">
        <location>
            <begin position="28"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ31286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="398" mass="42830" checksum="BFB5547F08B479BD" modified="2011-01-11" version="1">MKFSLGSLVLSAVSSLAVAVPINDILVYDAVIVGGGPSGLSAASALGRVRRNTLLIDSGEYRNAPTRHVHDVIGFDGVTPAWYRFSARQQISYYDTVTMTNGTVVQISGSDAENFVVSAIYANGSTVDVRTRKVVLATGLKDDLPDTPGLWENWGKGIFWCPWCDGHEHADQPLGLLSATFNDLPSLVREILTLNTDIIAFANGTDTPEARNSTEAKNPKFQEYLDLHNVKIENRTIANITRLRDGGEPAHDPSLPTAPENDLFSVNFVEGGEPVQRAAFFVSYPDEQRSTVGADAGVQLLGGRLSADVSKGLLTNVPGIYAIGDANSDNSTNVPHALYTGKRAAVFLHVRLAKEDQAKETGVDVGSLKRGAELSERSIWEVANGQPGDILYAGEYDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKB0</accession>
    <name>E3QKB0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Peptidase family M13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_06442</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M13 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697354">
        <property type="protein sequence ID" value="EFQ31298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095318.1">
        <property type="nucleotide sequence ID" value="XM_008097127.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKB0"/>
    <dbReference type="STRING" id="645133.E3QKB0"/>
    <dbReference type="GeneID" id="24411807"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06442"/>
    <dbReference type="eggNOG" id="KOG3624">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006187_4_3_1"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08662">
        <property type="entry name" value="M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1380.10">
        <property type="entry name" value="Neutral endopeptidase , domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000718">
        <property type="entry name" value="Peptidase_M13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018497">
        <property type="entry name" value="Peptidase_M13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042089">
        <property type="entry name" value="Peptidase_M13_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008753">
        <property type="entry name" value="Peptidase_M13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733:SF167">
        <property type="entry name" value="FI17812P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733">
        <property type="entry name" value="ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01431">
        <property type="entry name" value="Peptidase_M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05649">
        <property type="entry name" value="Peptidase_M13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00786">
        <property type="entry name" value="NEPRILYSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51885">
        <property type="entry name" value="NEPRILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M13 N-terminal" evidence="9">
        <location>
            <begin position="39"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M13 C-terminal" evidence="8">
        <location>
            <begin position="523"/>
            <end position="725"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ31298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="730" mass="80213" checksum="52DB2FB1F42618D9" modified="2011-01-11" version="1">MAPAGPNVDAGSICTTPACIEIASDILLSLAPNYTNIDPCTDFDQLACAGWNSKHAPGAGQNKASTLGEVSKTVSVILKDILESPYPTGPDAGFLTASLSKEQVSLDQDNFNLIVTTYNACLNNTVVEAAGLRPLMSLIDRVAAAFPVANTTEDRGRKVSKGDAENMGNTLLLFSQHGLSTFESIDVTFEDLNPNKTILSVLPGGSPLISRSQSRNDDTVKEYVRVVAGVLREVHPNKPTLSDAQRLAVDVIKFEREASALKSTDDSREGDDDYSPSKRFKLEQVTSVAPELNHDFVLKNLMPADYDPEALYFSPAYFGNLSQLLANTTVETVQGFFMWKAAAAFSPYVESPPTRRLSDFKSMLRAADPARVGRPARWEECVHHVDEGVPWSSVPKGLGWILSRFYLDRAYSKEARELATNMMGTIQQAFISRIGEKDWLSSDVKKAAEEKVKAITRKIGYPELSPDTANPRSLADYFSGLKIGDGYFDNAVAFATFASKQVFAQLGKPSDRGLWLQTPSTTNAYYYATYNDIVISAGIQQQPVYSVEYPSYVNYGSLGSILGHELTHGFDNNGHNYAANGSLANWWDDKSLEAFNNRTKCFVDQYQNFSVTAPNGTQVPVRGNFTLGENIADAGGVSTSYTAWKKLQGTMDAKDGDLPGLQRFSHDQLFFLRWAQTWCSKSSSKEYDVYLLGTDVHSPGFARIKGPLDNSKDFRSAFNCPQKQPTCELW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKL5</accession>
    <name>E3QKL5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acid phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_06547</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697355">
        <property type="protein sequence ID" value="EFQ31403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095423.1">
        <property type="nucleotide sequence ID" value="XM_008097232.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKL5"/>
    <dbReference type="STRING" id="645133.E3QKL5"/>
    <dbReference type="GeneID" id="24411912"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06547"/>
    <dbReference type="eggNOG" id="ENOG502S6H7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045947_0_0_1"/>
    <dbReference type="OrthoDB" id="2017497at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08589">
        <property type="entry name" value="PI-PLCc_SaPLC1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032075">
        <property type="entry name" value="PI-PLC-C1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16670">
        <property type="entry name" value="PI-PLC-C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180657" evidence="1">
        <location>
            <begin position="22"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="395" mass="42611" checksum="A430A0084C7FB36E" modified="2011-01-11" version="1">MAPMSNLGLKAAIFLLPFADAASPADQPYARDGLTWSAGAVRMNHVQVIGTHNSYHREAPLAEHPTQAGILPNVQNYYYSHPALDVQATYQSIRNFELDLFADPAGGHYATPLIRKLANLSTAPDSDLLGPGTKVLHVADADYHTTCKTLVGCLGAVQKWSAAHPDHVPIPFMIEFKTAEPEIAAAGGASPIPWNDTALLQVLDSEIRSVFAPGQLVVPDDLRRGNLTLEQSVLQHGWPDLESARGRVLFLMDNGPVHPVRDAYTDGRPNLEGRVLFTNSAPGNPDCAFQKLNDPTGAEQANIRAQVQADYWVRTRADVPLDTLLSNDTTAMREAAFSSGAQIVSTDFQAYGMSTRWDVDYAVRFAGGAAARCNPVNAGAGCVDAALEPVEYVRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLM5</accession>
    <name>E3QLM5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">DASH complex subunit SPC34</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Outer kinetochore protein SPC34</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">GLRG_06738</name>
    </gene>
    <organism evidence="22">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
            <location evidence="3">Centromere</location>
            <location evidence="3">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DASH complex SPC34 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697357">
        <property type="protein sequence ID" value="EFQ31763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095783.1">
        <property type="nucleotide sequence ID" value="XM_008097592.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLM5"/>
    <dbReference type="STRING" id="645133.E3QLM5"/>
    <dbReference type="GeneID" id="24412103"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06738"/>
    <dbReference type="eggNOG" id="ENOG502SCS2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064328_0_0_1"/>
    <dbReference type="OrthoDB" id="10016597at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042729">
        <property type="term" value="C:DASH complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005876">
        <property type="term" value="C:spindle microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008608">
        <property type="term" value="P:attachment of spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013966">
        <property type="entry name" value="Spc34"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08657">
        <property type="entry name" value="DASH_Spc34"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="16" id="KW-0137">Centromere</keyword>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="10" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="12 19" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="8" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-0498">Mitosis</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="53"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="203"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="19">
        <location>
            <begin position="230"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="70"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="20">
        <location>
            <begin position="206"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00044346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EFQ31763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="264" mass="28933" checksum="8AA99D5C030B47B9" modified="2011-01-11" version="1">MSMLSIHLEQIALSCEGIDSLPFPPPKIFTNAMLYNADITSLIRDTEAHERALFSVPPPPPSQSSSASQNTDSKPASGRRQTVFNVASGEVTTGPPPGSSRSGVGNMGGPRRHTAVSAVLGGDLHAQLRRGERQAASKGGDVDVEVLLKGAAKLCSVYALPGALERIPQLRSRYAHQTNTLAYYEAKVAEHQASLERMNKDHWMNEGDEGQQGEQEDEDEDEDLMTEDDLRAEEEIVRELDKKKRELQARLRTMEKDLGGLLNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLQ5</accession>
    <name>E3QLQ5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Microtubule associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_06768</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697357">
        <property type="protein sequence ID" value="EFQ31793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095813.1">
        <property type="nucleotide sequence ID" value="XM_008097622.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QLQ5"/>
    <dbReference type="GeneID" id="24412133"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06768"/>
    <dbReference type="eggNOG" id="KOG0161">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002168_1_0_1"/>
    <dbReference type="OrthoDB" id="10255000at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012943">
        <property type="entry name" value="Cnn_1N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019528">
        <property type="entry name" value="PACT_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47357">
        <property type="entry name" value="COP1-INTERACTIVE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47357:SF1">
        <property type="entry name" value="SPINDLE POLE BODY COMPONENT 110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07989">
        <property type="entry name" value="Cnn_1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10495">
        <property type="entry name" value="PACT_coil_coil"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Centrosomin N-terminal motif 1" evidence="7">
        <location>
            <begin position="174"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="Pericentrin/AKAP-450 centrosomal targeting" evidence="8">
        <location>
            <begin position="1294"/>
            <end position="1385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="93"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="624"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1052"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1342"/>
            <end position="1362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1052"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1062"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1081"/>
            <end position="1095"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ31793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1421" mass="163381" checksum="EE4CFAA7A4AEEE1D" modified="2011-01-11" version="1">MVAPGIGGLDTPRTNIGDATYLSRQPDFDISQEASFQSPPAKENNVLHQLRNGRSGGINLRTPRGRGPFADRKNLPAGLGGAEFTPMLKSATRNSIRRRSGKENGAVPNTPALGRVDEDMTPIPNIDTSMYQSRSFVDRTPLPEADSTSTATTPLVVLPRRDGKGPLQDGNQLSLREQESVIDKIEKENFGLKLKIHFLEEALRKAGPGFSEAALKENTELKVDKVTMQRELHKYKKHLTSAEKDLESYRQQMMDLQEKAKRKYADQKQLAEIERLQQALEDREADLDDMQRQLNQGQQDQGQVEKLQDEIGDLEAELREKERLLGDQEDEIDDLKTKLEEMEDKMKDTQRRMIELEQNAQSNDALEEAKDTIDELETNVRRLEDQVNDMKDKLNQAIADKEQAKGDLEELQDELANKSMVTKGLSRQKEEKLLRLQTELEEADSKFAHIEKQLSDTIKENENLKTAAKESLREREAADLEHQSRLARIELQLSEVTREKEKLKSIAEDGRQEQEFSDRERQSLLAQVEDLKHELQSRLDEKNLLQSRHEALTSESASLQRDVARLQKSVDELEESLAQERDHALEIERDIRGQYRDEIDRLNDEISDLQAEIREKDNLYDNDSEKWETDRHTLESERKRAEEKATGLERTIEKLREAEGNLSTKESRLQEALESEAQRHKDEQASLTRQIEDLQQNLESRQATLTELRGELSQVQDELRQTQLDYQAQTEKVEALEDEVEVLQTTLDEESEHSREELEAAKRECDTLRQQLDELRHGAVSVSQESAKSNQTIDRLRAQLDEATSLVSKLNKEKDLLQDQLQTQISESTVRVNKVSREKQSLQDQLASLNLEMHSLRSSLAEARAERDEIESGMKRMHQNGEETLRIDRERLDLRTSKMKLDNEVRRLKDENAALMEQMQSVEKSLEDEIEKAAEEEDRLNQEIRQLQAKLREVSSTEGHESVATRRTIRELERRIKDYEDQLALTQQLPANAGEGNSEISIIRRDLSTARQKEREYLQREAAHKEVVKGLKKQITELERKAHDAEMSRLIMSPASSSPSARKSEVSELRHQLSSAQQSMHDLKTKTRDAERRASQLERDFQTQLDDLEDQKLALEQALEDAQRDAEEAAALHEKALRRLQHKLERAEQDRQLVAHGRHNIDNMSSSERRDLQEMLRRTQTEADALEHDVIQQQETIDALMAAEGSLRRKLDRARSERAAYRLTAEKLQKDIRDLKRLAAAEQKDPQAVRFADQRMRETDEALETVIRAAENADAKHTKELRGMTLQMEWMQARWKREVSMRADAAYAKKFLQLELSIANACNKAQLRELEQIRCELLGSRKALPPPSSAPAKKHGTTASGRPTLKTVATMARFIARMRISAREWAKHEATRQRLANCVDEMRKTRRRKQLKVVPADDVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLS1</accession>
    <name>E3QLS1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">H/ACA ribonucleoprotein complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_06784</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Non-catalytic component of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP), which catalyzes pseudouridylation of rRNA and is required for ribosome biogenesis. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs. The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs. The H/ACA snoRNP complex mediates pseudouridylation at position 93 in U2 snRNA.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9 10">Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
            <location evidence="1 10">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 10">Belongs to the GAR1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697357">
        <property type="protein sequence ID" value="EFQ31809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095829.1">
        <property type="nucleotide sequence ID" value="XM_008097638.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLS1"/>
    <dbReference type="STRING" id="645133.E3QLS1"/>
    <dbReference type="GeneID" id="24412149"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06784"/>
    <dbReference type="eggNOG" id="KOG3262">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080002_1_0_1"/>
    <dbReference type="OrthoDB" id="2187159at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031429">
        <property type="term" value="C:box H/ACA snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034513">
        <property type="term" value="F:box H/ACA snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000454">
        <property type="term" value="P:snoRNA guided rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031120">
        <property type="term" value="P:snRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.230:FF:000001">
        <property type="entry name" value="H/ACA ribonucleoprotein complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.230">
        <property type="entry name" value="Probable tRNA pseudouridine synthase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038664">
        <property type="entry name" value="Gar1/Naf1_Cbf5-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007504">
        <property type="entry name" value="H/ACA_rnp_Gar1/Naf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23237:SF6">
        <property type="entry name" value="H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23237">
        <property type="entry name" value="NUCLEOLAR PROTEIN FAMILY A MEMBER 1 SNORNP PROTEIN GAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04410">
        <property type="entry name" value="Gar1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 10" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 10" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="124"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="144"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00053712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00062786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ31809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="214" mass="21480" checksum="74226EEEAB3443CA" modified="2011-01-11" version="1">MSFGRGAPRGRGGGGFGGRGGGGFGGRGGFQQRDMGPPATILEMGKFMHACEGEMVCESINPKVPHFNAQIFLENKTAVGKVDEVLGPINQVYFTIKPSEGIQATSFKEGDKFYIGSEKLLPLEKFLPKPKPPPGAPKVKRAGRGGPARGGRGGRGGFGGRGGAPRGGRGGSGFGGRGGGGRGGGGFGGRGGTPRGGGGFSSGRGRGGFSRGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLS8</accession>
    <name>E3QLS8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pyruvate decarboxylase</fullName>
            <ecNumber evidence="4">4.1.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">GLRG_06791</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2-oxocarboxylate + H(+) = an aldehyde + CO2</text>
            <dbReference type="Rhea" id="RHEA:11628"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:35179"/>
            <dbReference type="EC" id="4.1.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Binds 1 Mg(2+) per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the TPP enzyme family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.1" evidence="4"/>
    <dbReference type="EMBL" id="GG697357">
        <property type="protein sequence ID" value="EFQ31816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095836.1">
        <property type="nucleotide sequence ID" value="XM_008097645.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLS8"/>
    <dbReference type="STRING" id="645133.E3QLS8"/>
    <dbReference type="GeneID" id="24412156"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06791"/>
    <dbReference type="eggNOG" id="KOG1184">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013748_0_2_1"/>
    <dbReference type="OrthoDB" id="3970464at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004737">
        <property type="term" value="F:pyruvate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000949">
        <property type="term" value="P:aromatic amino acid family catabolic process to alcohol via Ehrlich pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02005">
        <property type="entry name" value="TPP_PDC_IPDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07038">
        <property type="entry name" value="TPP_PYR_PDC_IPDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000019">
        <property type="entry name" value="Pyruvate decarboxylase isozyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000024">
        <property type="entry name" value="Pyruvate decarboxylase isozyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012110">
        <property type="entry name" value="PDC/IPDC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme_TPP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047214">
        <property type="entry name" value="TPP_PDC_IPDC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047213">
        <property type="entry name" value="TPP_PYR_PDC_IPDC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43452">
        <property type="entry name" value="PYRUVATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43452:SF30">
        <property type="entry name" value="PYRUVATE DECARBOXYLASE ISOZYME 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036565">
        <property type="entry name" value="Pyruvt_ip_decrb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Thiamine pyrophosphate enzyme N-terminal TPP-binding" evidence="15">
        <location>
            <begin position="15"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Thiamine pyrophosphate enzyme central" evidence="13">
        <location>
            <begin position="211"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="Thiamine pyrophosphate enzyme TPP-binding" evidence="14">
        <location>
            <begin position="413"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="452"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="479"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="481"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR036565-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EFQ31816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="574" mass="63318" checksum="08789EAEF726BB8B" modified="2011-01-11" version="1">MADIRTQGLKQPVDVVEYLFRRLHEIGVRSVHGLPGDFNLVALDYLPECGLKWVGNVNELNAGYAADGYARVKGISAIITTFGVGELSAINALAGAYSEHIPVVHIVGCPSTISQKNGMLLHHTLGNGDFNVFSNMSSQISCDVARLNNPAEIANQIDHSLRECWIRSRPVYIMLPTDMVQKKVEGERLQTPINMEEATNDPVREDYVVDVILKSLHAAKRPIMLIDACAIRHRVLPEVHALLEKTKIPVFVTPMGKGAVNETHPNYGGVYAGTASQPHVSDRVESSDLILSVGGLKSDFNTAGFSYRTSQLNTIDFHSTHTRVRYSEYPGITMRGVLRKVTERLDLSQLTITTSPEVINRVPSPDSDPSQAITQAYLWPRVGNYLRENDIVVTETGTANFGIWDTKFPAGVTALSQVFWGSIGWSVGAAQGAALAAKDAGQDRRTILFVGDGSFQLTAQEVTTMLRHGLHTTIFVICNDGYTIERFIHGMEAEYNDIVQWQYKELATVFGGTDKTAKKFVVKTKDELEKLLTDKDFNNPTALQFVELYLPKEDAPRALIMTAEASARNNARAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QM18</accession>
    <name>E3QM18_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Oxidase ustYa</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_07050</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Mycotoxin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ustYa family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095926.1">
        <property type="nucleotide sequence ID" value="XM_008097735.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QM18"/>
    <dbReference type="STRING" id="645133.E3QM18"/>
    <dbReference type="GeneID" id="24412415"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07050"/>
    <dbReference type="eggNOG" id="ENOG502SNCH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042941_4_0_1"/>
    <dbReference type="OrthoDB" id="3687641at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043386">
        <property type="term" value="P:mycotoxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365:SF11">
        <property type="entry name" value="TAT PATHWAY SIGNAL SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365">
        <property type="entry name" value="YALI0B05434P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ31906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="290" mass="32681" checksum="988BDB5AFF67D28E" modified="2011-01-11" version="1">MKPEAMPYSDVRREAEIHNDPSMTDVSVSLLSDDGEGKQWNRADLEDGTRTTQPSRCARALGFFRRWRGLVDTLMLVIILGLLLERRAGLQPTTPRDKRLEPVGDLTGFAPEFTQQITTFHPTTDFVPDDPKKFFTNASIQENWLSIVPRGLGYVVMNDTKAHDNLPVPLPEFTPRTVFTTSMTHQLHCLYAILESYAGLAVNGSGAVDMHSHLPEGAQGSEEPWHLQHCFEYLRQAIMCAGDVALEGMQTTFPPGWTGSDGWGAKHVCKDYKQVYDYLDKNRAMDDHWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QM52</accession>
    <name>E3QM52_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">F-box domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_07084</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095960.1">
        <property type="nucleotide sequence ID" value="XM_008097769.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QM52"/>
    <dbReference type="STRING" id="645133.E3QM52"/>
    <dbReference type="GeneID" id="24412449"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07084"/>
    <dbReference type="eggNOG" id="ENOG502S1WE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020076_1_0_1"/>
    <dbReference type="OrthoDB" id="722566at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045048">
        <property type="entry name" value="FBXO31/39"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10706">
        <property type="entry name" value="F-BOX FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10706:SF130">
        <property type="entry name" value="F-BOX ONLY PROTEIN 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12014">
        <property type="entry name" value="Cyclin_D1_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="F-box" evidence="4">
        <location>
            <begin position="99"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ31940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="574" mass="63634" checksum="DF0B8807267D6FB7" modified="2011-01-11" version="1">MGVLGQMDSIPLSPSPSVAGTDDAAHDTVPTTGSNYGGIDAEVEENLYRLPYVSDEGLRSDATDRRKTISSCQGDYYPLSPDFSVSGSAEGHFLHLDTGCRLLSLPSEIIDAILAYLPPCDLAIVSETCRSLHAHATSDVHWYQRVQANVPGLKLETPYPCRTYRELYAAHDPRWFLPKYKIWFCDRDLMGKLIVVRYDQRRGCIEGYQLLAVSHRTTYQYWPADNNVVIHAFEPRVKLHLDKPVLQFHAHSVKDSENSTGLPEHGFLPEIPMVIDERPDAMFSNFLMARPLDTATATSRMEAPFPYGNVWPPPAIPARHRVAGVASGLDGDDLAPGDLPTRRAEASDQAFRIRQWMEMVGGPGPGLFLGAGPVGLIQAVHANMGMIGGRGVPGVHIGEEVVTYSTLDPVVYTPTPLKPWRGIWVGDYSGHGCEFLLINQPDEEDVSDEKLGLIRGVDESEDEWTRRRTDARVHRGRLEAIKLTGDPNVPRGEYTFVADDLGEAGFVGLAQEPPFQGTRVVRSKGHVAGTGFIDDKYIESQLMLISHDRLAQYWVGFGHISFFERVNIEEFVSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMC1</accession>
    <name>E3QMC1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">SNF2 family domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_07153</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096029.1">
        <property type="nucleotide sequence ID" value="XM_008097838.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMC1"/>
    <dbReference type="STRING" id="645133.E3QMC1"/>
    <dbReference type="GeneID" id="24412518"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07153"/>
    <dbReference type="eggNOG" id="KOG1001">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007345_1_0_1"/>
    <dbReference type="OrthoDB" id="448448at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18008">
        <property type="entry name" value="DEXDc_SHPRH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF17">
        <property type="entry name" value="HELICASE-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="280"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="776"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="157"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="693"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="182"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="224"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="711"/>
            <end position="732"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ32009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="968" mass="107949" checksum="09FDB893CD81DC7B" modified="2011-01-11" version="1">MAATDTVIQATREHDSSNDHLSMNADANSEVVAHEGGCPGGQPSPGALHHNTFMSMADDTFGDDDQDTVTSTGVQLPASALHDDAAMSIDEDAFGDEHEDMEISTRPAEKSTRRVTMARTAQEYTANLKNKSEQALKKHFIKHINLKRKSGDSIIFLEPPQAKRRREQKASTSSHGDPDKVVPPTTTKTDIVPELGGGIPGSDQHKVLKKDRRKQIAAATSEGDSNRHLSSQKKDAETGMKIWGLGAVECVGSSDYKLKGIRTPIRGWQLQAATLMVLRENSHAPPYGGILGDQMGMGKTLTSLVLIMGCPPLPQDIQAGCGGTIVVVPGPNVLKEWSEAITRHTDIRPKDVLVYKRGNNILEADQIAGYKIVLTTYQELLKYPSGKRLSNLAKEYGEETQEFQNAVKHVAGPIFDIEWYRIVFDELHTIKNSETQTFQACYRLKSKRVWGLSGTPLINQSKEIFPYFKLIGVEGCQTKSDFESIYKKGPDAFKKLDALINLITIRRNHENRFLGKQMLEGLPQFEAEVRWVNLSQEEQLIYNTIGQYFNSQSSPLPIVSMAQQRQAISHPYLLEKFFIETIDNESIQSLINELKEIEGNTWVYHQIGRRFGRRDPDNAFAAGENDDGDVPELTPRELAYAPMNPFGKSSFGESFSMVHLLELTVMDKEYSKSKCGRCKKKVTDRMRINGAAGCISSDDGSTDEDSDNRYRSRKTKVAEKRRKAQARREKRKMRRRKYGGDYIGNLPALEEHDTAFLQIGVNENGGVPCPGTKLTVAKEIILQWQEEAPNDKIIIFVEFIKTAVLMGIMLNLEDIPFVYLNGKLTSTEKLKAVDTFKTNPEVKILIASMKVGGQALNLTCANRVIQVDSWWNEAAGEQANGRVNRMGQLKPSHAVVIKVRGTVDDYITDLQDSKTKDIEHVLQDNGRVTEVLGEFEVMALTAPVAWQTLKERLVNDIEQDMGPLGVVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QN95</accession>
    <name>E3QN95_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">G-patch domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_07477</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697361">
        <property type="protein sequence ID" value="EFQ32333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096353.1">
        <property type="nucleotide sequence ID" value="XM_008098162.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QN95"/>
    <dbReference type="STRING" id="645133.E3QN95"/>
    <dbReference type="GeneID" id="24412842"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07477"/>
    <dbReference type="eggNOG" id="KOG1996">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025002_1_0_1"/>
    <dbReference type="OrthoDB" id="5411533at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000495">
        <property type="entry name" value="Putative G-patch DNA repair protein (Drt111)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040052">
        <property type="entry name" value="RBM17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13288:SF8">
        <property type="entry name" value="SPLICING FACTOR 45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13288">
        <property type="entry name" value="SPLICING FACTOR 45 SPF45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G-patch" evidence="2">
        <location>
            <begin position="343"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="317"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ32333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="512" mass="55372" checksum="EAAAABECB40C9933" modified="2011-01-11" version="1">MPAPPPPPPPARGGLSLYANLLDPAADSSPATISSAPVRYNQDGTVADAKDEVAAKKLIDPSLRFQPIRRPQAKTAKPKPSFPKKIPGANASATVATATTPSSASAPSVAAPQQPPPPKSTLADWAVTEEDEWRYTANAGGDKSHQRGGRRKKKKKGHNDQPAETNWDDIYDPTKPTNVEEYLRSDERIREVQEWKRLLYRHRKRRSSSEDSEDEPARRPAMNQFAPPPEYSFVPPPPASPPLASAASDADDTTGDDTYARRLGLSGAAPPPPTDASLPPPPPPPDAATISRAPVRYIPSTEPKMVAEEGSDRDSSPPALGLGATPAAADDEPPAPRSSRPGQAGFAQRLMSKYGWTKGSGLGVDESGIVNPLRVQVEKRKKRSDAEGGGWAEPANRAKILGGRRKNDGEGGKFGGPMSEVIVLQQMLDNMEDLQGEIANGLGQEIGEECGEKYGRVERLYIDVENRQVFIRFTDQVSALRAVNELDGRVFNGNTVVPKFYDTEKFERGVYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNA8</accession>
    <name>E3QNA8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dullard-like phosphatase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_07490</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697361">
        <property type="protein sequence ID" value="EFQ32346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096366.1">
        <property type="nucleotide sequence ID" value="XM_008098175.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNA8"/>
    <dbReference type="STRING" id="645133.E3QNA8"/>
    <dbReference type="GeneID" id="24412855"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07490"/>
    <dbReference type="eggNOG" id="KOG1605">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020262_7_0_1"/>
    <dbReference type="OrthoDB" id="277011at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000089">
        <property type="entry name" value="NIF domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011948">
        <property type="entry name" value="Dullard_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02251">
        <property type="entry name" value="HIF-SF_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="2">
        <location>
            <begin position="308"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="184"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="215"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ32346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="504" mass="55321" checksum="5AAFFD19378CCE45" modified="2011-01-11" version="1">MNSLNIITSRVSPPPSPVASRSNSISSLGLAVQSDNQRGGENAEKNDDDDQDDETFPLEKSAFEQRNNAHGMDLVSEATPLIGESKASGLRSTTWHSLPRRIAAGFINSLRWVLSTLAAPGVYLIACLYDEAGNFSPLLPLRRLFGFHGGNKKLATGYPDTMNEKSGRQGSTGYGGVAYSRPMGSSGSSSSGISSESESEADRHGRGSSSRHSRSASASEEIAPARRSIRIKLHSDDALPQRKHRKSQSAAARSKGNSQSGTSDISAQLKSPTSPAGALTRYPKTPAPPRPLIPRRQPSYLNLEPSTDPKYQKTLILDLDETLIHSMSKGGRMSTGHMVEVRLNQTYVGAGGQTSIGPQHPILYWVNKRPHCDDFLRRVCKWYNLVVFTASVQEYADPVIDWLEAERKFFSARYYRQHCTFRQGAFIKDLSSVEPDLSKVMILDNSPLSYMFHQDNAIPIQGWINDPTDNDLLHLVPLLEGLQYVSDVRALLALRGGEDGQHMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNJ1</accession>
    <name>E3QNJ1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_07748</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697362">
        <property type="protein sequence ID" value="EFQ32478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096498.1">
        <property type="nucleotide sequence ID" value="XM_008098307.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNJ1"/>
    <dbReference type="STRING" id="645133.E3QNJ1"/>
    <dbReference type="GeneID" id="24413113"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07748"/>
    <dbReference type="eggNOG" id="ENOG502QTC3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026014_1_0_1"/>
    <dbReference type="OrthoDB" id="2153847at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180757" evidence="2">
        <location>
            <begin position="20"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="286"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ32478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="561" mass="56311" checksum="A7E21F427B14643E" modified="2011-01-11" version="1">MKYQTVAFASSALLGLVSGAPQHLRRVSKREVPQEHSHEIFLDITRENLAKNNPKQISDPVFGLLGDAAAAKGAGQVTNLACLQQETADQAFTNAKAANDIRGMSAALVYQAIERNTAGVGKTSAACTDKAVNPEIAALVNKHQDPASDGAAANNKAVTLELAKQLASVGGDPMLALMSGTFAPGDKADTTGKGNSCDDANDPTGCIFTQKKLVLDATPDEITQAVKGITPTITGGTGELKAADVANVADFKVAGGAAAAAPAAAAPAATAPATVATAVTITVPTATPSATPAAGNDNDAGNQKNGASCKAKDNSAAADANNATAGADAAAGAAAPAGTNVTLGLRAPGIYQTILHWHRCDAQDTQCRSQAGLTKREAAGTNVQTFTGTLGGLPPPVIQSTGDRPFSVDGDTFVGKGAALGRSCDVQHNACARAANSGQISGGVSQCDAQDAQCRSQAGLTKREAAAGKFGSCSDPSIAFKSGLADRQGEAAFIANNQKDFAHGSAQKIGIIAGFICQRLQDSCKASAAVVNSCKAAQAAATAATQDATAANVFNSKLIGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNT6</accession>
    <name>E3QNT6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">PA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_07713</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M28 family. M28B subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697362">
        <property type="protein sequence ID" value="EFQ32443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096463.1">
        <property type="nucleotide sequence ID" value="XM_008098272.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNT6"/>
    <dbReference type="STRING" id="645133.E3QNT6"/>
    <dbReference type="GeneID" id="24413078"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07713"/>
    <dbReference type="eggNOG" id="KOG2195">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005688_1_0_1"/>
    <dbReference type="OrthoDB" id="5841748at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08022">
        <property type="entry name" value="M28_PSMA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02121">
        <property type="entry name" value="PA_GCPII_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000101">
        <property type="entry name" value="N-acetylated alpha-linked acidic dipeptidase like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.40">
        <property type="entry name" value="Transferrin receptor-like, dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039373">
        <property type="entry name" value="Peptidase_M28B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007365">
        <property type="entry name" value="TFR-like_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036757">
        <property type="entry name" value="TFR-like_dimer_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10404:SF71">
        <property type="entry name" value="CARBOXYPEPTIDASE TRE2, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G10650)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10404">
        <property type="entry name" value="N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04253">
        <property type="entry name" value="TFR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47672">
        <property type="entry name" value="Transferrin receptor-like dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="189"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="4">
        <location>
            <begin position="344"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="6">
        <location>
            <begin position="532"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="domain" description="Transferrin receptor-like dimerisation" evidence="5">
        <location>
            <begin position="782"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="143"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="75"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="149"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ32443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="915" mass="102228" checksum="67AF9D461795DEA5" modified="2011-01-11" version="1">MPSDRDQRYESVPPIPSYDEALATGGPADPNEWQIPRSPMDGRSQNETESQSLLNRNGVATSSRRPNGYRPPTVESEDEESSWSSDGEGDETAYVRREMQELEMGHPDDRSRPSLWGKRIPFSLSLPQWPSWRWRLPRLRPTIRLPSGPNESSNDTNDANARTTTTTTTTTTRLRITLPQWDKDKTRTAIIIFARVFAVVFVMGILYALFMSDLFTTMARRMNGGLRFNPEDVRMYIQNNVEDRRMKASVAHYTKYAHMAGTEGDYALAMDVESMFTRAGLDYVNIDEYYVYLNYPKAGGRAVEILGDDGKAKWAAKLEEEEVGGEAAGHQTFVFHGHSKSADVNGPLIYVNYGSRSDFKKLADSGIDTKGAIALVRYYGSQESPALKVKAAEEAGFAGCIVYSDPADDGFRLGDVAPNGRFMPADGVQRGSVALSNWVLGDPLTPGWESKKNLPRMKPEETKGLVKIPSLPLSWRDAQVLLQHLKGHGEQVPKEWAGGVPDVGEWWTGNLSSPIVRLKNDNDVVQEKGIWNVYGKIEGIEQDQKSIIIGNHRDAWSFGATEPHSGTAIMIEMARIFGSLVAKGWRPLRSIEFMSWDAAEYNMIGSTEFVERNEDLLRQNAFAYINLDSAVAGTEFHAAGSPVFRQTVYRVIDRVFDANLNATLRGLWDQHGSDLEDLGMGGDYVPFQNIVGTSALDVGFRGARFPAQSSYDNYEWVNRIGDPDFAYHVMMGQVVGLLILELADRPILPFDMLAYGNRIERYVNDLSNFCEHRGASAQSKFSLEPLKNIVNNAKDNLKAFALWEMAWESTVMGGGGYETGEMGDKRLQFNNHMADFETALLDLEQGGGMPDRPQFKHVIFGPQAWSGNKPVTFAGIRDAVEAGDWELANKMVEKTARIIRNATNMLQEWKKSVES</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNV4</accession>
    <name>E3QNV4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">chitinase</fullName>
            <ecNumber evidence="3">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">GLRG_07556</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the glycosyl hydrolase 16 family. CRH1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="3"/>
    <dbReference type="EMBL" id="GG697363">
        <property type="protein sequence ID" value="EFQ32542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096562.1">
        <property type="nucleotide sequence ID" value="XM_008098371.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNV4"/>
    <dbReference type="STRING" id="645133.E3QNV4"/>
    <dbReference type="GeneID" id="24412921"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07556"/>
    <dbReference type="eggNOG" id="ENOG502QVQI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027506_1_0_1"/>
    <dbReference type="OrthoDB" id="4781at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02183">
        <property type="entry name" value="GH16_fungal_CRH1_transglycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF27">
        <property type="entry name" value="GLYCOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179888" description="chitinase" evidence="15">
        <location>
            <begin position="23"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="300"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="16">
        <location>
            <begin position="45"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="397"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="397"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="428"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="466"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00038074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EFQ32542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="504" mass="53877" checksum="84B2AE8CA3C9CEC6" modified="2011-01-11" version="1">MLSQYALSAVALLASFAQPTLAQVSTKCNPMNATCPADPAFGMDYSFNFNSTPSSDAWETTVGPVKYTAANGAEFTISKQGDSPTIRTKFYFFWGRTEIHMRAATGQGIVSSMMWLSDTLDEVDWEFLGVRNDALSNYFGKGVEDFHNGGEHPVTGSIHDDFHNYTCVWTKEKLEWWINGNNVRTLLPQDANNSMAYPQTPMRLSLGIWAGGDPRMAKGTQEWAGGETDYAAGPYTMYVKSAQVTDYSSGKEYSFGDKSGSWESIKVAEGNSTVKEALLAEPSKSVSEKFDALSPTAKTAVYAGGVGVGCALIAFGLFYIIRQRRRGAAEARLAAEKAESERLELEGFHKRGVDPDSFAGSTGTEYNAAEFSKNGMAQGNAYSVPATQEKDVWDSAPAAAGAASPGAYSDSPNGRGQVPSPLHMQSPGMPPSGPLPMAPSRSTSQGGYSRLGSPGSPHSPPPMSPPSQGHSNYGFNNQQGYSNGGYGDANQGHWNNGGSQGGFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNZ2</accession>
    <name>E3QNZ2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nuclear distribution protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07594</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697363">
        <property type="protein sequence ID" value="EFQ32580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096600.1">
        <property type="nucleotide sequence ID" value="XM_008098409.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNZ2"/>
    <dbReference type="STRING" id="645133.E3QNZ2"/>
    <dbReference type="GeneID" id="24412959"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07594"/>
    <dbReference type="eggNOG" id="ENOG502S5XV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091042_0_0_1"/>
    <dbReference type="OrthoDB" id="5403729at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005869">
        <property type="term" value="C:dynactin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061640">
        <property type="term" value="P:cytoskeleton-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009991">
        <property type="entry name" value="DCTN3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07426">
        <property type="entry name" value="Dynactin_p22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="136"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="204" mass="22662" checksum="8BD31173BDDAEC7D" modified="2011-01-11" version="1">MDNSLDNTTLSTVSLLESRLLRIEHLLYGPTAASPPPQTESVVEMLEELERRFNHLMSRIRVYGELMRLYHSHPTLFQPPPPSEPPTQLAPEAVQATVLASAASFPATASSLTSVNDCPIPETSQSAALASLVPKMRGIEATQMAQEAEMAELRARSEEVLKSWYQQGVLSASEFIAEVEGRVERVERHVRRARREKEDEAAVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQV3</accession>
    <name>E3QQV3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Endocytosis protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">GLRG_08385</name>
    </gene>
    <organism evidence="23">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the PAN1 actin cytoskeleton-regulatory complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Actin patch</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the END3 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697368">
        <property type="protein sequence ID" value="EFQ33241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097261.1">
        <property type="nucleotide sequence ID" value="XM_008099070.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQV3"/>
    <dbReference type="STRING" id="645133.E3QQV3"/>
    <dbReference type="GeneID" id="24413750"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08385"/>
    <dbReference type="eggNOG" id="KOG0998">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040829_0_0_1"/>
    <dbReference type="OrthoDB" id="1716625at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00052">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000339">
        <property type="entry name" value="Actin cytoskeleton-regulatory complex protein END3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000261">
        <property type="entry name" value="EH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025604">
        <property type="entry name" value="End3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216:SF74">
        <property type="entry name" value="ACTIN CYTOSKELETON-REGULATORY COMPLEX PROTEIN END3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216">
        <property type="entry name" value="EH DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12763">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12761">
        <property type="entry name" value="End3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00027">
        <property type="entry name" value="EH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50031">
        <property type="entry name" value="EH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="12" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="16" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="11" id="KW-0967">Endosome</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EH" evidence="20">
        <location>
            <begin position="9"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="21">
        <location>
            <begin position="41"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="EH" evidence="20">
        <location>
            <begin position="138"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="343"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00025194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00029684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="EFQ33241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="397" mass="44937" checksum="B9F2E4FCDC09A6E1" modified="2011-01-11" version="1">MAPRIEAQEIETYWNIFSARTGGGQFLTGEQAAPVLKNSGLTDNQLERVWDLADVDNDGNLDFEEFCVAMRVIFDILNGEYSDVPTTLPDWLVPESKAHLVQANRALTGRQVAFEQVEDDPDSPGLKDGFDWYMSPQDKSKYESIYQENRDARGEVAFTALEDLYESLDVPDTDIRSAWNLINPSASPSINKDACLAFLHILNNRHEGFRIPRTVPASLRASFERNKIDYQLDNQTPGASRWATKADDSTATGRKAKFGDQYLTRLGRSGFKSSGTDFSTAKTDDWEEVRLKKQLQELDEKMARVEADVERKKGGKRDSKPALVKRELEQLLDYKRKQLRDLEDGASKAKGGASLQSVSDDLQTVREQVEGLETHLSSRQHVLEQLRREIEDEKLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>E3QR95</accession>
    <name>E3QR95_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">RuvB-like helicase</fullName>
            <ecNumber evidence="15">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">GLRG_08662</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the RuvB family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="15"/>
    <dbReference type="EMBL" id="GG697370">
        <property type="protein sequence ID" value="EFQ33383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097403.1">
        <property type="nucleotide sequence ID" value="XM_008099212.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QR95"/>
    <dbReference type="STRING" id="645133.E3QR95"/>
    <dbReference type="GeneID" id="24414027"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08662"/>
    <dbReference type="eggNOG" id="KOG1942">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028311_1_1_1"/>
    <dbReference type="OrthoDB" id="10060499at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031011">
        <property type="term" value="C:Ino80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097255">
        <property type="term" value="C:R2TP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000812">
        <property type="term" value="C:Swr1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000492">
        <property type="term" value="P:box C/D snoRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000010">
        <property type="entry name" value="RuvB-like helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.360:FF:000001">
        <property type="entry name" value="RuvB-like helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.360">
        <property type="entry name" value="RuvB-like helicase, domain II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027238">
        <property type="entry name" value="RuvB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041048">
        <property type="entry name" value="RuvB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042487">
        <property type="entry name" value="RuvBL1/2_DNA/RNA_bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010339">
        <property type="entry name" value="TIP49_P-loop"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11093">
        <property type="entry name" value="RUVB-RELATED REPTIN AND PONTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06068">
        <property type="entry name" value="TIP49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17856">
        <property type="entry name" value="TIP49_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0010">Activator</keyword>
    <keyword evidence="7 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 15" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4 15" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12 15" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 15" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13 15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 15" id="KW-0804">Transcription</keyword>
    <keyword evidence="9 15" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="16">
        <location>
            <begin position="63"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU363048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EFQ33383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="458" mass="49670" checksum="3C881EEB33B54482" modified="2011-01-11" version="1">MVQISEVKGNSRENRTAAHTHIKGLGLKQDGTAEKQAAGFVGQTTAREAAGVVVDLIRAHKMAGRGVLLAGGPGTGKTAVALAISQELGTKIPFCPIVGSEIYSTEVKKTEMLMENFRRAIGLKVRETKEVYEGEVTELTPEEAENPLGGYGKTISTLLIGLKSAKGQKKLRLDPSIYEAIQKERVSVGDVIYIEANTGACKRVGRSDAYATEFDLEAEEYVPIPKGEVHKKKEIVQDVTLHDLDVANSRPQGGQDIMSMMGQLMKPKMTEITDKLRGEINKVVSKYIDQGVAELVPGVLFIDEAHMLDVECFTYLNRALESPISPIVVLASNRGMATIRGTDDIIAAHGIPTDFLARLLIIPTTPYQADEIKRIVRIRATTEGVPITDAALDKIAEHGVRISLRYCLQLLTPASIISKANGRSQIDVQDVAECESLFLDSRRSASLLSGESGKGYIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSZ7</accession>
    <name>E3QSZ7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GYF domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_09129</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697375">
        <property type="protein sequence ID" value="EFQ33985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098005.1">
        <property type="nucleotide sequence ID" value="XM_008099814.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QSZ7"/>
    <dbReference type="GeneID" id="24414494"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09129"/>
    <dbReference type="eggNOG" id="KOG1862">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001585_1_0_1"/>
    <dbReference type="OrthoDB" id="48509at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00072">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051640">
        <property type="entry name" value="GRB10-interact_GYF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003169">
        <property type="entry name" value="GYF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035445">
        <property type="entry name" value="GYF-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14445:SF36">
        <property type="entry name" value="FI03272P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14445">
        <property type="entry name" value="GRB10 INTERACTING GYF PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02213">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00444">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55277">
        <property type="entry name" value="GYF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50829">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GYF" evidence="2">
        <location>
            <begin position="714"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="852"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="957"/>
            <end position="1162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1181"/>
            <end position="1242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1259"/>
            <end position="1283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1316"/>
            <end position="1335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1414"/>
            <end position="1445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="472"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="498"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="957"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="977"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1004"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1047"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1058"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1084"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1096"/>
            <end position="1118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1141"/>
            <end position="1162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1184"/>
            <end position="1193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1227"/>
            <end position="1240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1426"/>
            <end position="1435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ33985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1466" mass="152201" checksum="8392DE5AEE61F91D" modified="2011-01-11" version="1">MPSNLPSSFASAAAGQNSSRDARTGRPDGRGAGSGEWARRDGRANGTLTFRRSSVTPGHPSQSAASSENAFLATSLESAAPPQTPGAATYDYSAPSQYQKESILGVFKQGAAETDTVNVFESGWTPGQTNGGAARGWGKTNNNHNSQDPAACWNPRGDGHPVGVNGLSEEEKEAFAADVNSPLKAPIQKQEGNLGPGTNGRKPSLSHGNAAGYGLASPSSASRPGTRRRETTDSNPFGTGALASPSAARFARGDDAFLFGRKNNDVKEQDPGEDEGAGQPQNQAQPKPPYGNLTRSNTTGNPSMGANISSLWGASSQTSVPGGSGGGGSSSSGGMGSFGQFALPTPTSTIGTGSRGGSRFANLMNKDGSDNTSGKTNEAPTPDATRSWRSRPRTDTDPFGGDDNLSGSAALGGAQDTSPPPIPNPSNIGMFETPVKGSTGDFGMSGLNLGHQAENEPGPASPSETNPYRSPPADRGESHDEGGAEKPHGAAIGGEQNPGFNTMSSRGFPTHAFDGSDRSQTSSAGPRGYASGWPVPMSTGTPDRERAGFGGVFGNSLFSPMGTELQSPGLSSIGAGVFGPASAGGLGGAGTIGRSKLGSLFPPAMQAQMQGHEQENLSDSLPDLRQGNPLGAIGRNNFNAVPRDAGSPLRAGRGGVFEEMFPSDPTRSHSVFGGSDPSHPGAPGVGHPQVFTPGASTGTEFGSAPVRQMVMPDRMRWVYLDPQGHVQGPFSGLEMNDWYKANFFTPDLRVKKVEDSDFEPLGQLIRRIGNSREPFLVPQIGIAHGPPSQAGPFSPSGNTGVIPPLSGVFPSFGRTLTAEEQNNLERRKQEEQQAMAQQRDFMMRQQAITRLQSQGPGGVPGSLHHQHSAHSLQSQPSFGSISSPIGAHPQQPPIGGGVGPTSSFFDAAAQQASAQPPVGAGLDHFREEDLATLNPSERQMLASVQAPNSIASIFNQQPVGAPANDNNLRNNLPGTKQLDKDEEGFRERLKEFEDIRAERDSEQTQESGNKTNQDDGSQEAPAATGSETSSMENHKPSAPGMKEIMEQQEQLSLTQRVQQAQAAAEAAKNAAAGFPMPFPPPAPTTGTPLPAPTAQRVRSNLPEQYNRSQTGTPDTGSATEPPPLAPWAKEAASRKGPSLKEIQEAEARKAAKAEEAAAERRRVALEQEAAALREREKAIASATGLPTTSTWGNGSPVAAASPWTKPASVKPTPGASTPGKQKTLADIQREEENRKAKAAKEVAVQTGLATAAAGKRYADLATKPNNAPGLGQTNSPAPPPGSGWAMVGAGGKVKVPTGPASQTRSASAAGMKATPVATKPAVKPPPAAAPAGPAKSDVAMDEFNKWLHRELSRGITGVDIDTFAATLQILPLDNTIIADAVYANSKTMHGLHFAEEFIRRKRLAEKGVVEKQGAVTDNKSGSWNEVAKKGGHKEQSPASAAAGDASIQGAGFKVVPTRKKAGKKGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3QT08</accession>
    <name>E3QT08_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09140</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697375">
        <property type="protein sequence ID" value="EFQ33996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098016.1">
        <property type="nucleotide sequence ID" value="XM_008099825.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QT08"/>
    <dbReference type="STRING" id="645133.E3QT08"/>
    <dbReference type="GeneID" id="24414505"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09140"/>
    <dbReference type="eggNOG" id="ENOG502RSFR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1461206_0_0_1"/>
    <dbReference type="OrthoDB" id="10254945at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ33996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="185" mass="21443" checksum="5E556AE3E65FE6F6" modified="2011-01-11" version="1">MAPEPWWLQTQPPEVDPDRLSDPSLPKPDTVQLDSLFWAESIQLLRLGGLRAHESQILQEVEPYTPRLPKGLSGYGSEDSSENEEDTSSDDKDDYSIDDEQGGTSLFPIHKMPTAKPRPWMERDFVEVDETKWFKLFRRERWASYLNQDPLQLSVDISNDKDWAKLSRVIEIANRILSEAVNQQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QT32</accession>
    <name>E3QT32_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_09164</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697375">
        <property type="protein sequence ID" value="EFQ34020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098040.1">
        <property type="nucleotide sequence ID" value="XM_008099849.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QT32"/>
    <dbReference type="GeneID" id="24414529"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09164"/>
    <dbReference type="eggNOG" id="ENOG502RA2W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_526758_0_0_1"/>
    <dbReference type="OrthoDB" id="2520703at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ34020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="440" mass="50300" checksum="842BF9B146AB2FCC" modified="2011-01-11" version="1">MEEDDTFSKVNLYNLCLVDKKWHQAATPSLYHTFESRWDRSFFTFLPTLIQHPNLAIHVKCVSLSLDYQNWPWEDTKTFRNVIRSRALALGSPFSDHPALVADKNSNRLSRDYQCVLGEMLLFHTPNIVSIDFVKETEVEKVFKFLDTVACCSQKWHGMRRLRRVKLDVRFAEDIPESHYMGYLSRLAAVAPSVQHLHTYLLGDCRPPLLDWAPVTVQSQVPTPPHMVTFLSSLRSINITNSTDSIPFERTLGAHISHCKSIEEVRYLSGNRDVASFMQLMRPLSRTIKRLGCTQWNAQGNETIWDPLRNDSVAVIETIAGLTSLEALLFDLTGPSVLSEHGDSASTIVPFMCALPKSLRVLAIGGCNWVCLKQGLSQLMDRVHDGMLPNFRTLHVGCYNESHHHPFIEAFAEFGVKMKMHENLWLYEDALRKVWMHMGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QT96</accession>
    <name>E3QT96_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SGNH hydrolase-type esterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_09228</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697376">
        <property type="protein sequence ID" value="EFQ34084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098104.1">
        <property type="nucleotide sequence ID" value="XM_008099913.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QT96"/>
    <dbReference type="STRING" id="645133.E3QT96"/>
    <dbReference type="GeneID" id="24414593"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09228"/>
    <dbReference type="eggNOG" id="ENOG502SIJX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005594_1_0_1"/>
    <dbReference type="OrthoDB" id="2119228at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004622">
        <property type="term" value="F:phosphatidylcholine lysophospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01833">
        <property type="entry name" value="XynB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051532">
        <property type="entry name" value="Ester_Hydrolysis_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383:SF5">
        <property type="entry name" value="SGNH HYDROLASE-TYPE ESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383">
        <property type="entry name" value="THIOESTERASE 1/PROTEASE 1/LYSOPHOSPHOLIPASE L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="Integrin alpha N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="2">
        <location>
            <begin position="56"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ34084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="913" mass="99696" checksum="8FACA6AD4DF61E8D" modified="2011-01-11" version="1">MVNDNIKRKGSLPLVPEVASFGTCELEPSSPATLRYKRTKPGKEVKPGTELRILGVGDSITVGFLSDRNGGDGNGYRLQLRDDLSKDKVVFAGSETMSGTMDGNRFGAWSGQTIQHISDHIGPSLKQRPNIVLVHAGTNDMNPSLDTAKQGNDPKGAADRLGKLLDKIIEACPDATVLVGMIINTCDEKQSPATKEYQQLIPGVVKSRKDGGKHILAADFTTFETSHLQDCIHPSNDGYKLFGSYWYDFITQIPKDWIQKPVGDGPKDDGNNGGLDKNIPAPDWGADPVTPTTPDTVRGAYLNARPVETHTCNAKPFWGAGGQIALGNIGRNGDWKYKKNWVEAGKVADGLHRDPRFVRLHDMNGDGKADYVWIHPDTGEIRCWINNLPEPWSKAGTNDDIIGSGAGPADLVFIALEDYMVVNRNNGSVEIWWNYGPDDSWVNGWKFVEGGEIASGVPHANWETLRFPDINGDGRADYVYIGEGGALQHHLNTGSVGGQDVLFLAQGGIASGAVDDISRLVFADKAFHCTPYIDQEPAKTLADGISQKPESIRLADLDGDGKDDYAYIDDDGAIWLWYNRGGGHTSMLIDGLRFADIDGDGTDDYVWLDPETGAPIVYTNYGYNANDEAFGYRWIPLNDGKPIASGAAPASQVTFGRITGNDKADYIVVDPESGKLSVWQNMGPGKNSPDNWGWNEINVDASGLGPGKNVRIADIDGDGWDDYIMLNKKGGTTIYRNMYLNSEEDHVWKPLPAADAEGIGQRPDEISDGKADYVWTRPHDGAVFAWYNNYPNQPAWLPQGQIAEGWTSGHFVKWASMYLKRFEKLAKPWTSYLAVRPSDGALAVWFNGCKFGDHGPPTTLAPHSKAKSSSIQSFSNGIVSSTPYNSSYPFANTSKPLKSASKPIIRARLQHLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUH5</accession>
    <name>E3QUH5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_09657</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697381">
        <property type="protein sequence ID" value="EFQ34513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098533.1">
        <property type="nucleotide sequence ID" value="XM_008100342.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUH5"/>
    <dbReference type="STRING" id="645133.E3QUH5"/>
    <dbReference type="GeneID" id="24415022"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09657"/>
    <dbReference type="eggNOG" id="ENOG502RQRP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043284_0_0_1"/>
    <dbReference type="OrthoDB" id="4491390at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053175">
        <property type="entry name" value="DHMBA_Reg_Transcription_Factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38791:SF12">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38791">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="2">
        <location>
            <begin position="8"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ34513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="491" mass="53530" checksum="4A6FA1F1509DE83D" modified="2011-01-11" version="1">MRCRPLASCFACRTSKVKCDLQKPSCRRCEGRGKPCPGYADPWAVAHRSENATAALQVELRIAKRLKEREAPSDAASIAGGGKANSLAAAAGESVRRRSTVPKQLQVDSEFVWLERFYSNYACADETAWFSLLAGLRASRTTSAAFEGAIRATALASCAMQTRQAGLMVLARRYYGSAIAKINSALQNPTTAQDDSVAVALLAMCIYEGLIPEEMSPKAVSHCKGSLMILRYRADQGVASSLDSRILAFVAHIGVLQVFAGGERRDLLFPVVKSASWTRHAVVEPLLARAVEFKGTVDSVMTSIKSREAPITGILQTGLDIIRDLEAAANYRIMSPGPRKTSRQTGAMGEESNNFNNLLSRSSYATEAALKGLYLTVRLQVIEFILNLSMAHGEPTCEELGILTSLPHGLTAVEQICEQVRVLFGFDGREPASRNQGIAFNAWCMLWPMITVLQSGFTDRETQLWMMDKLTLIGGLAERSVYSGVWTNSRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUI1</accession>
    <name>E3QUI1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09663</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697381">
        <property type="protein sequence ID" value="EFQ34519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098539.1">
        <property type="nucleotide sequence ID" value="XM_008100348.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUI1"/>
    <dbReference type="GeneID" id="24415028"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09663"/>
    <dbReference type="HOGENOM" id="CLU_2793852_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="68" mass="7332" checksum="94B6054B4731C2E0" modified="2011-01-11" version="1">MLDATSLAAATHGHSQTPLLGPSKLRSEAVGSRYPSYEFTLMGPPEGYAIHPVRSRQPVSTFASFERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUQ5</accession>
    <name>E3QUQ5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_09737</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697381">
        <property type="protein sequence ID" value="EFQ34593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098613.1">
        <property type="nucleotide sequence ID" value="XM_008100422.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUQ5"/>
    <dbReference type="STRING" id="645133.E3QUQ5"/>
    <dbReference type="GeneID" id="24415102"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09737"/>
    <dbReference type="eggNOG" id="KOG1515">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012494_6_4_1"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="3">
        <location>
            <begin position="109"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ34593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="363" mass="41006" checksum="F1C53812F8CA92AA" modified="2011-01-11" version="1">MTVATKLNEQPSPKAGDGRLALSAADYPGIDPEWVRLWNEHGGGMTRADEVTIEQYRESPAQYSFTYPTCKGPDVFHVEDRKVPVTQPSGEITVRVYSPEGPGSFPVHLNFHGGGWVLGGLNSEAAWCRHICNKSNIKVIDVDYRMGPEHKFPAAIYDCWDTVKWAIRNAADLKIDPLSVSFGGLSAGGQMSAVLAHFARDESIPIKLHMMIVPATDMRYCHRKFTQLNESNCPYESARLYHDLPWGPLGREQWFLKYWLGDDDDQQQKCLDDWRLTPVLAPNLKNLPPAHIITAEFDLERDEGEYYGKLLRDAGNEVSMKRYAGVPHAFAHYNHPQRGLAKSFEFIDDTAELLKSTHYGDRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUS0</accession>
    <name>E3QUS0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Midasin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09752</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697382">
        <property type="protein sequence ID" value="EFQ34608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098628.1">
        <property type="nucleotide sequence ID" value="XM_008100437.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUS0"/>
    <dbReference type="STRING" id="645133.E3QUS0"/>
    <dbReference type="GeneID" id="24415117"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09752"/>
    <dbReference type="eggNOG" id="ENOG502SF70">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068910_0_0_1"/>
    <dbReference type="OrthoDB" id="2873061at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35587:SF6">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35587">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="149"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="286"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="346" mass="38670" checksum="9EA198AE7E914E65" modified="2011-01-11" version="1">MARNKNKKGQGQGAAGNQQPGSSKPEEQQQFEDQKPGEQQPEEQKPEGTTPVGEFGNPGDEAQTGEAKDMPEDASKPEDPKPEEPTEDRPKDQSSQDEEKKPGEDVEPQDAQQQDASQGDEPKAGDEQSLTEDEKKRKKQKQLEEEQKQQQQSQEQQKTPGQDADDKKQEPSSASKQAGVEDEAEPESKPAADKDGEKPSTADQTAKDQKPSKLDGDEEEVEDDGGEYYDDDDDDDNVEDDDVEDEEDYSEDDDEEDYDEDEDEDYDSEEDDEDDGGYQNGQMTRQQQQQMQQQQQMQMQQQQMQMQGGGGGDAGKNPLKLRLDLNLDIEITLKARIHGDLTLALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVA8</accession>
    <name>E3QVA8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Glutamate decarboxylase</fullName>
            <ecNumber evidence="3 9">4.1.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_09940</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 9">
            <text>L-glutamate + H(+) = 4-aminobutanoate + CO2</text>
            <dbReference type="Rhea" id="RHEA:17785"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:59888"/>
            <dbReference type="EC" id="4.1.1.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the group II decarboxylase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.15" evidence="3 9"/>
    <dbReference type="EMBL" id="GG697384">
        <property type="protein sequence ID" value="EFQ34796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098816.1">
        <property type="nucleotide sequence ID" value="XM_008100625.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVA8"/>
    <dbReference type="STRING" id="645133.E3QVA8"/>
    <dbReference type="GeneID" id="24415305"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09940"/>
    <dbReference type="eggNOG" id="KOG1383">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019582_2_2_1"/>
    <dbReference type="OrthoDB" id="5152799at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004351">
        <property type="term" value="F:glutamate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006538">
        <property type="term" value="P:L-glutamate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000017">
        <property type="entry name" value="Glutamate decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.160:FF:000004">
        <property type="entry name" value="Glutamate decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.280.50:FF:000001">
        <property type="entry name" value="Glutamate decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010107">
        <property type="entry name" value="Glutamate_decarboxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01788">
        <property type="entry name" value="Glu-decarb-GAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43321">
        <property type="entry name" value="GLUTAMATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43321:SF6">
        <property type="entry name" value="GLUTAMATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="502"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7">
        <location>
            <position position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ34796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="531" mass="59019" checksum="0CA1B6800B082B4C" modified="2011-01-11" version="1">MVHLATVNTPPDSGSDDSDTTAELKKVQQQLSKVQLQLADEDDSFTTSVYGSRFANQDLPRAEMPEDEMPKDIAYRMIKDELSLDGNPMLNLASFVTTYMEEEAEKLMTESFAKNFIDYEEYPQSADIQNRCVSMIGKLFNAPVGAGVGAVGTSCVGSSEAIMLAVLAMKKRWKNARQAAGLPADRPNIVMSSAVQVCWEKAARYFEVEEKLVYCAPDRYVIDPAETVALVDENTIGICAILGTTYTGEYEDVKAVNDLLVEKDMDVPIHVDAASGGFVAPFVVPDLEWDFRLKNVVSINVSGHKYGLVYPGVGWVVWRSAEFLPQELVFNINYLGADQASFTLNFSKGASQVIGQYYQLIRLGKKGYRAIMSNLTRTADYLTRSLEVLGFVIMSKRSGEGLPLVAFRLPDDAAAGEDGGRTYDEFALAHQLRVRGWVVPAYTMAPKTNDLKMLRVVVREDFSKARCDSLIADIKLCMGLLEQMDHASVQRQQDFIHRHHLTSSKASHNHPKFRKEKHSIQGKHGKTHAIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWJ6</accession>
    <name>E3QWJ6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Restriction of telomere capping protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_10378</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May be involved in a process influencing telomere capping.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RTC4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697390">
        <property type="protein sequence ID" value="EFQ35234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099254.1">
        <property type="nucleotide sequence ID" value="XM_008101063.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWJ6"/>
    <dbReference type="STRING" id="645133.E3QWJ6"/>
    <dbReference type="GeneID" id="24415743"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10378"/>
    <dbReference type="eggNOG" id="ENOG502SEU0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_874901_0_0_1"/>
    <dbReference type="OrthoDB" id="128308at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039024">
        <property type="entry name" value="RTC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028094">
        <property type="entry name" value="RTC4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41391">
        <property type="entry name" value="RESTRICTION OF TELOMERE CAPPING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41391:SF1">
        <property type="entry name" value="RESTRICTION OF TELOMERE CAPPING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14474">
        <property type="entry name" value="RTC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01312">
        <property type="entry name" value="RTC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Restriction of telomere capping protein 4 C-terminal" evidence="9">
        <location>
            <begin position="215"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="51"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ35234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="348" mass="38776" checksum="7754D7A42715D40E" modified="2011-01-11" version="1">MQSSQEKAATKRKKEGRSPSPKRPQPSFKAYDDDPFDQFSGKAPQKDLIKLPSLPSSPSGSPPRSKFQKHSSLSPGASPRRTTKAKFKHPSGSLPEPLRSPKRGSADLLDLESSHEALYKRHKGEKDSFLDISDHSISDIDTETRCPMCSEIVENALLEGFSGGARLHIRMQIQFCRLHKKKSAEDAWDARGYPKIDWEILGSRLATHYDFLRKIINGGSSHYASLLVDKVKEGKDRTLLKAEDSLTPGYYGPRGLRAMSESIIGNFSSILRERAVEDRVISSRGYSSYVEAVLVPELAVQLICEDMEVKIDEARKILKESKWIGDLLHDDAGDTVDQLSDDEQVGGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWV1</accession>
    <name>E3QWV1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_10483</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697391">
        <property type="protein sequence ID" value="EFQ35339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099359.1">
        <property type="nucleotide sequence ID" value="XM_008101168.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWV1"/>
    <dbReference type="STRING" id="645133.E3QWV1"/>
    <dbReference type="GeneID" id="24415848"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10483"/>
    <dbReference type="eggNOG" id="ENOG502SF08">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032510_0_0_1"/>
    <dbReference type="OrthoDB" id="5278722at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="507"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="507"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ35339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="565" mass="62428" checksum="49D5864E22B65EF4" modified="2011-01-11" version="1">MSNELPRHERRPSSPTQYSSSSKSTFGPCDMSIKTLLGFISTRVLRGGPRFIIQLILAAFGLLLLGKFLASPTSTDTLFSSGSRWSWSPFSESKGQQGVGVRVVVFGSPDIATPSTDKGVEGKGWTEMLCDELRCSSHQSFIPSTSLPAQAMTTTKHYRDTLENLTSKVDHSKPFGYNYSFLVDQFPLSDAIANLTSQIDAFLALPKPHDVPRETVWVFTFGTWDVWTLASLPRDVGGKILDAAVEALFAQVERIYQASLDADSVAFSDFWAHQDTISPLAELNAMEQGRDVVDPREIENFRVIVPELFDVSMTPGWQAQRPAPPQPHNKAEQMTNAAYLTTKWNSEVKSCMDEWMRTPDPEPEDGDEDDFGYVATRVRRSFNEGDAPLVVPFPRRVGAQVDAASFIREAIVERQMRNQGLTDATGRGNRTGGEQGNVFFSETWVPCIWASTSNASETAEAADKYAACGARDDYLFHSPFTLSQRAIRETARIAAAEARRTLAFVDRTEGGEGEGRKQGETKEPAAAAMSKRRERRGQLSGFQRITLPDHSVRPVNVVCPSADVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWW4</accession>
    <name>E3QWW4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glucanase</fullName>
            <ecNumber evidence="9">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_10496</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glycosyl hydrolase 7 (cellulase C) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="9"/>
    <dbReference type="EMBL" id="GG697391">
        <property type="protein sequence ID" value="EFQ35352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099372.1">
        <property type="nucleotide sequence ID" value="XM_008101181.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWW4"/>
    <dbReference type="STRING" id="645133.E3QWW4"/>
    <dbReference type="GeneID" id="24415861"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10496"/>
    <dbReference type="eggNOG" id="ENOG502SJT6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020817_0_1_1"/>
    <dbReference type="OrthoDB" id="412382at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07999">
        <property type="entry name" value="GH7_CBH_EG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.100.10">
        <property type="entry name" value="Glycoside hydrolase, family 7, domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001722">
        <property type="entry name" value="Glyco_hydro_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037019">
        <property type="entry name" value="Glyco_hydro_7_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33753">
        <property type="entry name" value="1,4-BETA-D-GLUCAN CELLOBIOHYDROLASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33753:SF1">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE CELB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00840">
        <property type="entry name" value="Glyco_hydro_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00734">
        <property type="entry name" value="GLHYDRLASE7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 9" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 9 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180930" description="Glucanase" evidence="10">
        <location>
            <begin position="19"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ35352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="418" mass="45511" checksum="E9082EC6E11EC036" modified="2011-01-11" version="1">MALSIISISLLLFNLVSGQAPGKGADNHPKLETFRCTVDNGCQKKTNYIVADSSQHEITTSSGVSCDTGDNPPNSTACTTPEDCASNCVINAISDYNAVAVTTSGTDIRMKIFNDSGTEIKPRVYLLEENKERYEMIYLTGAEFTFDVDMTKLPCGLNAALYLSEMPPDGGKSSNSLNKLGPAWGTGYCDAQCFKTSFINGVGNFDGKGSCCNELDIWEANARATHIAPHPCSQPGLYECVGEECEKAGVCDKAGCSWNPNVINATHYYGTGDNFNVDTTRNFTVVTQFPSENGKLKELRRMYVQDGKVIQNNVVNIEGPPKIDFMNDDYCQATGATEFSRLGGMEVMGDAMTRGMVLALSVWWDKVTFMQWLDVGNNGPCNVTEGNPVVARKIVSNPEVTFSNIRYGEINSTLNMKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXC9</accession>
    <name>E3QXC9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DHH family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10661</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697394">
        <property type="protein sequence ID" value="EFQ35517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099537.1">
        <property type="nucleotide sequence ID" value="XM_008101346.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXC9"/>
    <dbReference type="STRING" id="645133.E3QXC9"/>
    <dbReference type="GeneID" id="24416026"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10661"/>
    <dbReference type="eggNOG" id="ENOG502QQ02">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034130_1_0_1"/>
    <dbReference type="OrthoDB" id="284473at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1640.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051673">
        <property type="entry name" value="SSDNA_exonuclease_RecJ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30255">
        <property type="entry name" value="SINGLE-STRANDED-DNA-SPECIFIC EXONUCLEASE RECJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30255:SF2">
        <property type="entry name" value="SINGLE-STRANDED-DNA-SPECIFIC EXONUCLEASE RECJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="DHH phosphoesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="435"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="448"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="459" mass="49359" checksum="CEA25BB74F50FDEB" modified="2011-01-11" version="1">MEISVQGKILHPRAQCLPVAMKRSAATANLANGKQGIKKLKPAIPEYHLAPSVRGEDGGIVWPAADDKMEAARAFIRECVSAGKPTLIVPDKDADGLASGAILERTLVLLGLDPSLITAYLPPKGKNVHDESCRSEMASHEPAYIFILDQGSRSSPPLIDGPHRGIVIDHHHALEGDHPEGALHVTACDSPPVATSSLLTYLICRDLHDGVEGACDWLCVMGTHGDLGNTLKWEPPFPDMKTTFKRYTKKALNDAVSLINAPRRTASYNVPSAWEALRAATSPQELLADTSLLAARAEVNAEVERCTHTAPKFSADGRVAVFRISSRAQVHPVIATRWAGHLASARLEVVLVANEGYLPDLVNFSCRVPRCARARDPPVNIIAVLEDVAARSGDPTLRDRLGGSFARGHKEASGGIVPRAEFEELMAVLEVGKKAEGASPKKARKPAQANTLTNYFGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXH9</accession>
    <name>E3QXH9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_10711</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697395">
        <property type="protein sequence ID" value="EFQ35567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099587.1">
        <property type="nucleotide sequence ID" value="XM_008101396.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXH9"/>
    <dbReference type="STRING" id="645133.E3QXH9"/>
    <dbReference type="GeneID" id="24416076"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10711"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_1_2_1"/>
    <dbReference type="OrthoDB" id="6770063at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF60">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="229"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="297"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="344"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="384"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="411"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="480"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="74"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ35567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="524" mass="57252" checksum="CB5A8E8BE99A0E5A" modified="2011-01-11" version="1">MDGSTASAARGWEKQDPPRPTMGDDGGRGGGVANARNKPAGAADDLEADNIVTWDGPNDPANPANWPMMKKYQTSLILSLFSFIAPFSATMVGPAMEVIGTELNIAPGTEQQLIQGMQVLAAGVGPFFIAPIIELFGRANVIRYAHLWHLIWNTACGFATSGPQLLAFRFIGGLGASAPQILAPGLTADVYPAPMGGRGDAVHAYLPFFGSAIAPIFGAFVTQESNWRWIFWGTSIFSVIAVALAFLVLDETYHPVLLERKAARLRQETGNQRLHTPFHDPNQSNSDRILKRAALPWFMLVSHPIVQLPFGYRAYLFGIMYFVISTYGQNFMSVYGMDKESASLNFLSLAIGFVVGLHISRYAIDGFSAYFRRRHKTTGHAPEWRLPVNGGAALFLPPALILYGWGLRNELHYIIINISAFLLAIGLILGYFSLQPYVTESYGLEYASSAHSVGAFLQHIAEFAFPLFGPSVTSSDLAFGWSYTLLAALTLAICTMMPLILWHFGPAIRRVSTRGLPVEPSGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXN7</accession>
    <name>E3QXN7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_10784</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697397">
        <property type="protein sequence ID" value="EFQ35640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099660.1">
        <property type="nucleotide sequence ID" value="XM_008101469.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXN7"/>
    <dbReference type="GeneID" id="24416149"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10784"/>
    <dbReference type="HOGENOM" id="CLU_3068568_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="2">
        <location>
            <begin position="20"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ35640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="53" mass="6351" checksum="5829F298DE4E3717" modified="2011-01-11" version="1">MEGIDEQSTTAELVVSREDRQRTRNRLAQRRHREREHTLSSTCLLPEVMQTIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXP0</accession>
    <name>E3QXP0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tripeptidyl-peptidase II</fullName>
            <ecNumber evidence="4">3.4.14.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">GLRG_10787</name>
    </gene>
    <organism evidence="19">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Secreted tripeptidyl-peptidase which degrades proteins at acidic pHs and is involved in virulence.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal tripeptide from a polypeptide.</text>
            <dbReference type="EC" id="3.4.14.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="15">Binds 1 Ca(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
            <location evidence="3">Extracellular space</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.4.14.10" evidence="4"/>
    <dbReference type="EMBL" id="GG697397">
        <property type="protein sequence ID" value="EFQ35643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099663.1">
        <property type="nucleotide sequence ID" value="XM_008101472.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXP0"/>
    <dbReference type="STRING" id="645133.E3QXP0"/>
    <dbReference type="GeneID" id="24416152"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10787"/>
    <dbReference type="eggNOG" id="ENOG502RX52">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013783_3_0_1"/>
    <dbReference type="OrthoDB" id="5230128at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008240">
        <property type="term" value="F:tripeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04056">
        <property type="entry name" value="Peptidases_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11377">
        <property type="entry name" value="Pro-peptidase_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000015">
        <property type="entry name" value="Tripeptidyl peptidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015366">
        <property type="entry name" value="S53_propep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050819">
        <property type="entry name" value="Tripeptidyl-peptidase_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218:SF39">
        <property type="entry name" value="PEPTIDASE S53 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218">
        <property type="entry name" value="PROTEASE S8 TRIPEPTIDYL PEPTIDASE I CLN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09286">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00944">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51695">
        <property type="entry name" value="SEDOLISIN"/>
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    </dbReference>
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        <property type="entry name" value="SUBTILASE_SER"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11 15" id="KW-0106">Calcium</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 15" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="10 15" id="KW-0720">Serine protease</keyword>
    <keyword evidence="8 16" id="KW-0732">Signal</keyword>
    <keyword evidence="12" id="KW-0843">Virulence</keyword>
    <keyword evidence="13" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180009" description="tripeptidyl-peptidase II" evidence="16">
        <location>
            <begin position="21"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S53" evidence="17">
        <location>
            <begin position="244"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="15">
        <location>
            <position position="335"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="15">
        <location>
            <position position="339"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="15">
        <location>
            <position position="555"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="597"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="598"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="616"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="618"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EFQ35643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="652" mass="71385" checksum="BDD34639D6F5B404" modified="2011-01-11" version="1">MSSWKMLPFLCVLFATLVHCFPSSQTNQQQQPHRIRDAIRQPLGWKRTTRAETDTVVHLQIGLKHDGFKELERRLYECKCPSPATRVHTSTEIHHLLKPSAETVRKAENWLIEHGITKYDMTPARDWIRASVPVRTAEALLDSEFYHFESDNDGHVLVRTLEWSLPGHLRGHIDVVQPTNSFLRTVPQDRYGGIQKPAWEVEGRVPTYDELVEEDLVERGHIDIPALADLPPNPTVADACNRLAISSLCLRVLYGTLDYEVQQPVDVNATNKVGVVNFLGHNNNRSDIARYLELYRPDAAAAGAAAAFETVLVAGAVDQQTPNTPEQMSRAMGLEGALDVETLLGVAHPVPLVAWNVGGRPPFQPSANKVQNSNEPYLEWLNHLAALDDAALPRVVSVSYADEEQTVPPRYAARVCEAFAQLGARGVSVIVASGDEGVGKEGKCVSNDGTETPRFMPTFPASCPYVTAVGGTRHFEPVMAGFDARGGFSTGGGFSNYFRRPSYQEPAVAAYVAGLNTTHQDLYNPQGRGIPDVAAMAYHFPVVWNGTSHLLDGTSASAPAFAAIIALINDALLAEGRPSLGFLNPWLYSSALPGLRDVAVGSNRGCGTMGFPAVEGWDAATGLGMPWFPVLKQLALRDAFRWDHPWYVTNLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXV1</accession>
    <name>E3QXV1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_10844</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697398">
        <property type="protein sequence ID" value="EFQ35689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099709.1">
        <property type="nucleotide sequence ID" value="XM_008101518.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXV1"/>
    <dbReference type="STRING" id="645133.E3QXV1"/>
    <dbReference type="GeneID" id="24416209"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10844"/>
    <dbReference type="eggNOG" id="ENOG502S6E5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022883_5_1_1"/>
    <dbReference type="OrthoDB" id="3061561at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35043">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35043:SF7">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180924" description="Integral membrane protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="480"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="513"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="569"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ35689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="639" mass="70955" checksum="24683F471BE4F3F4" modified="2011-01-11" version="1">MICSLRSFFLLPILGSANAYPSTTGWASEPNGRGTFGLICSCVLTLTICVWTALHLNVPAIRSTLRSRAIERGKWVLYGIFAPELVVATAAAQYIVARWLKREIEKDTAYRHSAGVATNRTEGRDGQMPSRHTWDMTQCFYAVMGGFVVDLPSVDNEDDAFRRVTVTPEGLRLLSFMGKLPGIHESQIQDKSKADWMAKSLVCIQAGWMVTQVIGRLIRKLPVSLLEINTCGHVACAVLLYLLWWSKPFDVMDPTVLEGGTNNLLSLMTVCSSIDAINGVTDIRCFQYMPGQEFTGEGSQDQRAAKILITTHLSIGSPGIREPSGFLGFDISDIRPHLSPLTVEKHTQRVPRSAYMYHIDQSKPTVSPECLQTYFVPPYINLSLRHSNLYCRRIFADVQQYQKSHKHKPVNPIRLAEAAKAADGLWAMCAARPTYTPYYFTFVPTVGVFLGETEYIVSHIVNFPSISNLGLGQVNIHRDVLRSVLALTAAAYGGLHLIGWVDHFPTQIERRMWLVASLVIACSGVALWIFFLARQAWPWFDVFVSGAAPGARLTSARYQKPWMRKVKRLVLVSIIVVFVVARVFLVVEAFLSLKEAPSALQLICTLDISAAARVDEDDLAPTSIRGNVFPRSSITAIGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYJ9</accession>
    <name>E3QYJ9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Hsp70-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_11045</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697403">
        <property type="protein sequence ID" value="EFQ35937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099957.1">
        <property type="nucleotide sequence ID" value="XM_008101766.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYJ9"/>
    <dbReference type="STRING" id="645133.E3QYJ9"/>
    <dbReference type="GeneID" id="24416410"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11045"/>
    <dbReference type="eggNOG" id="KOG0101">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009958_6_1_1"/>
    <dbReference type="OrthoDB" id="2963168at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10170">
        <property type="entry name" value="ASKHA_NBD_HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187">
        <property type="entry name" value="ALPHA KINASE/ELONGATION FACTOR 2 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187:SF5">
        <property type="entry name" value="HEAT SHOCK 70 KDA PROTEIN 12A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ35937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="602" mass="66740" checksum="3A063CF076F5D751" modified="2011-01-11" version="1">MADTDNTIVIGIDFGTTFSGVSWAFSGQPNEIEVITSWEAEMNYASDREKAPTAILYRGTQNAVSWGYEIPVDEIQDAMRWFKLLLIDEADLPDNLKHSPQITTARKAVKATNKDAADVIGSYIRRLWNHSIESIGKSVGDELVKMCKFHVVITLPAIWPDYAKARMCRAAEHAGLLEERPAGQTTLAFISEPEAAALATMRDLAGRPNIKVGDHFVVCDAGGGTVDLISYEVLGLKPMVVREAIKGDGELCGGVFLDEAFVNLIKDKVTTKAWDNVPKAEAANVLNGDWEHGIKQQFDGKHDRQWHIQLPPECKVKKTPERGIKRKRNLMLNLQDLLSVFDPIANKISSLVQKQIDGVRNKSGKPPKNVILVGGFGRCRYLHSHLRSAIDKDIALLQATGAKPWTAICRGAVVQGLTQQNLSPGLSISVKSRIARASYGIEVRTKFDRKKHSNRFKNWSEGEQEWMAHGQMKWFLEQGTDVSSTAPVSENFYELYSSAPPEVSVSLHVSSAWPPPSEKDSSVRDLCKITWGKKIDFEALPRHVNSLGKVFHRLDFTVEMVCTGASLDFSVTHEGKRVGAKNVSVAFDTEADDVKTKRSPSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYK1</accession>
    <name>E3QYK1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Tyrosinase copper-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_10818</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697404">
        <property type="protein sequence ID" value="EFQ35939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099959.1">
        <property type="nucleotide sequence ID" value="XM_008101768.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYK1"/>
    <dbReference type="STRING" id="645133.E3QYK1"/>
    <dbReference type="GeneID" id="24416183"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10818"/>
    <dbReference type="eggNOG" id="ENOG502R5VY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035914_2_0_1"/>
    <dbReference type="OrthoDB" id="6132182at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF126">
        <property type="entry name" value="TYROSINASE-LIKE PROTEIN TYR-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00497">
        <property type="entry name" value="TYROSINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180947" description="Tyrosinase copper-binding domain-containing protein" evidence="3">
        <location>
            <begin position="21"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="4">
        <location>
            <begin position="83"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="5">
        <location>
            <begin position="234"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ35939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="329" mass="35873" checksum="5E743D2DEE449998" modified="2011-01-11" version="1">MVKSLTTATLCLGMIQAVSAACTNPAQRKSWSALTSTEKAEYIDSTLCLMDPAQAPSKTGFAGSKSRWHELQVAHIAQVQFIHSVGAFLPWHRWFMTVHENLLRSECGYTGPIPYWNEQVDQAAGPLTAASIWGNDSSTSFGTGSTDSNGCLLDGPFKNVKYNVDIQLQRGAEHCLAYDLKQDEFDLVSQALVDACNTLESYSDFNSCLGGSPHVSGHYAIGGTMDDVSLSPADPLFFMHHTNLDRLWWVWQSKNTSRLTDMGGPNVASGFLASVQPTILPVEAFAPYFGDNGNTTTLDHILWMAGTAENITIAEVMDVKSDAICVEYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZ48</accession>
    <name>E3QZ48_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11280</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697410">
        <property type="protein sequence ID" value="EFQ36136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100156.1">
        <property type="nucleotide sequence ID" value="XM_008101965.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZ48"/>
    <dbReference type="GeneID" id="24416645"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11280"/>
    <dbReference type="eggNOG" id="ENOG502T4YQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1421339_0_0_1"/>
    <dbReference type="OrthoDB" id="10359283at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="203" mass="22632" checksum="DEF49A759BA2F803" modified="2011-01-11" version="1">MPSNNPRQLNLGNLIPKILTATFVLVLAILYAHTYHLGPSEIGAPLLSRQYTPPSETTVRICTALHSLRALEPDRPSSAPTPFDFFHLDARAAPFHPPRDAARIGSKNHQAVIKAVVKAGRENREMLDQSLWRGGGSSSAGQELAKAELADRASWFVTDMLIDDEARTYFLEHIQPRLNKLRTAIDAIEGLCGQMWRERGWEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0U4</accession>
    <name>E3R0U4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_11880</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697492">
        <property type="protein sequence ID" value="EFQ36732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100752.1">
        <property type="nucleotide sequence ID" value="XM_008102561.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0U4"/>
    <dbReference type="STRING" id="645133.E3R0U4"/>
    <dbReference type="GeneID" id="24417243"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11880"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_25_2_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF223">
        <property type="entry name" value="CYTOCHROME P450-DIT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="504"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ36732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="574" mass="64765" checksum="2360DF3FA8F5A479" modified="2011-01-11" version="1">MNSVIVAAAVLPVLYLVNSIFCLVRNVRVAKKLGISVVCSPISPFNPAWIIFNKRVVPFLQRLPFGLGDWTRCNTLDWTWIDRAHGDRQIHKRHGDTFANVTPRGIEIHTRDQAVVNQVLRKYTNEFPKLGSFAKVMDVIGTSVVSSDGADWAHHRKATVATLNDRNNGLVWAETIRQTRQMARYYSKVSQGRIVDAVEDIRELYLHVFTYVCYGVKYEFKQPAHTTIPAGHSRSYKECLHSSINGILMLRLVPWWMMGMPGMPSRIRNFRQAILELQEYLDEMISSCQERLAQGQVEKEGENLLSFMVRRSKESQDQPKTKADNHLSESEIRGNLFTYARGGHESSAHTLTFMLYLLAAMPEVQEWLMQEIKEVLVGDDIWWQSEEAFLGVFARLKRCQAAVNETLRLYPSVIVIPKTNPLPATLRVGHGEIHVPSGTNLYVNMPGVQVHEGTWGPNAMTWDPRRWVDTPVAAGDISDSLATERLLPPPDGAFVPWSEGKRACPGKRFSQVGLVAALATILAFHKVEVIPNDGESAEAARGRTLAAVNNTYAVMSVHMYQPYSVRVKMVQRKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3R132</accession>
    <name>E3R132_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glutathionylspermidine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_11966</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697574">
        <property type="protein sequence ID" value="EFQ36820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100840.1">
        <property type="nucleotide sequence ID" value="XM_008102649.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R132"/>
    <dbReference type="STRING" id="645133.E3R132"/>
    <dbReference type="GeneID" id="24417329"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11966"/>
    <dbReference type="eggNOG" id="ENOG502QUZK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059175_0_0_1"/>
    <dbReference type="OrthoDB" id="64566at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005494">
        <property type="entry name" value="GSPS_pre-ATP-grasp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03738">
        <property type="entry name" value="GSP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutathionylspermidine synthase pre-ATP-grasp-like" evidence="6">
        <location>
            <begin position="15"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ36820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="444" mass="50934" checksum="403F099A3B069BC4" modified="2011-01-11" version="1" fragment="single">MRRIPVQKRKNATRLVQSQGLVYGHLSSYRTTEPYWPDNRYYSFTLEEITLLENAAKDVFAMCCEAADYLVEHSDIITEKMGVPAFALQQIMESWDRESPWGSIYGRFDVCFGGLDHADSRLRVPKFYEFNADTPTSLVEACLIQWLWLEQTGYGNDQFNNIHEALIEGWGRNLTLIEKKLGHKPTVHFAFSSGNHSGEDMMNTMLLLETCQQAGWAAKKLNMEEISLSTEDGRFYDMEGQHIDVIFKLYPWEFMTGQEFAKPCFKDMDNVGKRDEEGNYIGGTIWIEAPYKMLWSNKSLFAILWELFKDDPRSKWLLPTYFDNEAPTSLTSFARKPIFAREGADIVLKEKGKVVQDSSVGWYGAEGYVIQELALLPEFKDIQGKSHYPVLGLWMVDGDSVGMGIREDETPVTTNESVFVPHSIEDGPVTYQRQEIPSDEEIEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3R162</accession>
    <name>E3R162_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11996</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697650">
        <property type="protein sequence ID" value="EFQ36850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100870.1">
        <property type="nucleotide sequence ID" value="XM_008102679.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R162"/>
    <dbReference type="GeneID" id="24417359"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11996"/>
    <dbReference type="HOGENOM" id="CLU_2885650_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003181146" evidence="1">
        <location>
            <begin position="19"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="63" mass="7058" checksum="6C4C10857EB6AFF6" modified="2011-01-11" version="1">MKVPFILSLALIVAQVQATCYKCRWTWCMILLIQMLPVAQKVDEREMVTAILTSTVTGEVKSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2F8</accession>
    <name>E3Q2F8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_00403</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089279.1">
        <property type="nucleotide sequence ID" value="XM_008091088.1"/>
    </dbReference>
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    <dbReference type="STRING" id="645133.E3Q2F8"/>
    <dbReference type="GeneID" id="24405768"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00403"/>
    <dbReference type="eggNOG" id="ENOG502S48N">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030366_0_0_1"/>
    <dbReference type="OrthoDB" id="1939603at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039327">
        <property type="entry name" value="CON7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36167">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36167:SF3">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="270"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="46"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="293"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="46"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="137"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="229"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="300"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="332"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="396"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ25259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="431" mass="46536" checksum="4B84BA9D45F9AC07" modified="2011-01-11" version="1">MFVVPTQHQFVDNHASLLSSSSPQLGGSRPEAAAISSLLTSLSTSMERSATEYSQSGLPSPYPSNCGDTRSEGSSADHASAAQYATQQEVRSSNYSTSATPTSEYSVYPPSARSGSFPEHIQRSYHPASNHNGSSGGMAQQASSPSLPQQDGRNHQVPMPKSDHDVPIDPSIAAPSPTYAYGQHSPYGPPPGDMSHSYQHPAYAQPRPDWTGYGQHSAGPLTPASHVFPPTPSSAPPQGRPNQVYSFVPIPGAQQHKRPRRRYEEIERMYKCGWNGCEKAYGTLNHLNAHVTMQSHGQKRTPEEFKEIRKEWKQRKKEEEAQRKAEDERQRQAAAAAAAAAQNGSGDPQSGPDGSSSASAYASGRQVQLPPIGYQPSQYPAPPSAGGVAQQPLPEYNSSHMYSANYQPQSPYGQPNQSMYSSRELKTPGAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2I3</accession>
    <name>E3Q2I3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00428</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089304.1">
        <property type="nucleotide sequence ID" value="XM_008091113.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2I3"/>
    <dbReference type="STRING" id="645133.E3Q2I3"/>
    <dbReference type="GeneID" id="24405793"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00428"/>
    <dbReference type="eggNOG" id="ENOG502SEYQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023523_0_0_1"/>
    <dbReference type="OrthoDB" id="5411141at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="299"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="363"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="602"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="647"/>
            <end position="656"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ25284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="656" mass="70368" checksum="A3E8843FFBDC27D3" modified="2011-01-11" version="1">MAPHAVPPGRRALKRRARPANIAVSPSLWERDAESDDEYANQVRNAAGGVWKRTAKSGIRPSDDTLERRSDSDSGDRGRGSQYSEPSSPDTPKTRPSYNLPAIGRLPVASLRPALPAVSNLPSTTLPAFEPAITSQAPVLEPPMFFQPVVPQPRPTSHMMTPYRPLQPVDPQPAPVLAPADPESTPRESEVPIPPATMTVTSPPRTITVISTMKPASSFDLIMVTLSAGDHPIIDAAYVSSFVDRPGYFTTFAVLTATLASAALPAETLSALPGPASAVSDRGGDDGRPSRMNPETEHALIAVGSIGSFIFASFLVWIVWRTMKKASRRRRERELGYPNDRPGIGSKIPFFKGSMGGWQNIDGRQSDPTQYEKGPRGTLRLDTGFYGPNGKPANYGPGGTYVPNYMSPVDSRGSPIHGSPTGALPVRMNPMNGGTYNGQQGVFNSQTGTYTSQVGTFSSQTGTYVSHAPSGSLTHIIGQYGNGTEPGMTLRSGVGAGAYFNQSELARQPSDAYDPARRQVNRASELSSISSGFGDGDIIVPGMPGMVLQPPPPVSQSLRASRMDNDRVSWANKSNRETVYTEASEDLPPRFRTVDSWVNQQSGRVKRAQARPQTDEDIPPVPGLPAGTGQNGMPPEPQFTMMMPDGEVPRRPDNAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2M1</accession>
    <name>E3Q2M1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arrestin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00466</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008091151.1"/>
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    <dbReference type="STRING" id="645133.E3Q2M1"/>
    <dbReference type="GeneID" id="24405831"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00466"/>
    <dbReference type="eggNOG" id="KOG3780">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070086">
        <property type="term" value="P:ubiquitin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF174">
        <property type="entry name" value="ARRESTIN-RELATED TRAFFICKING ADAPTER 10-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01017">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="2">
        <location>
            <begin position="481"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="323"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="571"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="728"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="863"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="113"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="351"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="575"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="771"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="863"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="875"/>
            <end position="884"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01017"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EFQ25322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="931" mass="102896" checksum="194CAC3C4BD16932" modified="2011-01-11" version="1">MTDSERSRRTENWIPTSTRGGVYYCPRYLLDPPAAQQNRLPTPPIRARQVRPRSIHITSWPSGFVPHELRPQPERPVKRRKPPNPVSPATTSLGKTSLKFSFKQFFSLSQKQVPSRSASSASTPSRPPLSRPPSRATSLLNRLSSYREVDLVVPEEDTMALRSAAMSETMRPPLMSSAYNTPGQRSSLISVRSAKSNVTSMVTEIPKPVAHGSGVSCSILMAEPNVFLTGFDHDGHRQHSQGGTALLRGKLQLKVTKNVKIKGVSLKLAGKARTEWPEGIPPLKVDLYEEESLRTQVLTFFNAVNDGWESEYGNQCVYTLKNSSTNSSSTNLASGSPRNSISQSLLSVPLNSNNNNNSNNNNNNNNNRQGMTARELKRLSLQSNQSRSFGKGDNPSGNQAKGYKVFYPGVYEYNFELPIDHHQLETTKLQYGSVKWELQATVERAGAFKPNLHGSKEVAIVRVPDQLSLEMTEPISISRQWEDQLHYDIVISGKSFPIGTKIPIAFKLTPLAKVQVHKLKVFVTESVEYWTNDRRVTRKDPGRKILLLEKTAGKPLDPAYASSDVRVLNGGELTPRQRREARESAAMRRAAEASRHGMMPDPLPEPVDNILGDLDLGLESYWGSTEIEMNVQLPTCDTMAKSKELRLHPDCSWKNVNVYHWIKIVMRISRLDPDDPTGTKRRHFEISIDSPFTVLNCRATQANTSLPEYSGPDMCANQSRQTSCGCPDAVTISGPPEGSPNNLSTGALTVVDGSDNLPAPPQAAHLPSSPQPGTGATTSRHGQTSPPTSQTNVDPFSDTHPRPIHLLRVPSYNPPAFDAEVPPPPAEEQLRLQTPPPQYDVIVGTPSVDGMADYFARLADYGYDEPEEDSDSDEGPARITERGGRVNVAHPRTPGGRRAPSRSMEIQRPPLELRMETLPALRRSDVPSQIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q362</accession>
    <name>E3Q362_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">1-phosphatidylinositol 4-kinase</fullName>
            <ecNumber evidence="2">2.7.1.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_00185</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19877"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57880"/>
            <dbReference type="ChEBI" id="CHEBI:58178"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.67"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.1.67" evidence="2"/>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089061.1">
        <property type="nucleotide sequence ID" value="XM_008090870.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q362"/>
    <dbReference type="STRING" id="645133.E3Q362"/>
    <dbReference type="GeneID" id="24405550"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00185"/>
    <dbReference type="eggNOG" id="KOG0903">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002446_2_0_1"/>
    <dbReference type="OrthoDB" id="10264149at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004430">
        <property type="term" value="F:1-phosphatidylinositol 4-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006995">
        <property type="term" value="P:cellular response to nitrogen starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
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    <dbReference type="GO" id="GO:0140504">
        <property type="term" value="P:microlipophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000786">
        <property type="term" value="P:positive regulation of autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042998">
        <property type="term" value="P:positive regulation of Golgi to plasma membrane protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050714">
        <property type="term" value="P:positive regulation of protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd05168">
        <property type="entry name" value="PI4Kc_III_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1010.10:FF:000035">
        <property type="entry name" value="Phosphatidylinositol 4-kinase PIK1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1070.11:FF:000016">
        <property type="entry name" value="PIK1p Phosphatidylinositol 4-kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021601">
        <property type="entry name" value="Phosphatidylino_kinase_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015433">
        <property type="entry name" value="PI3/4_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001263">
        <property type="entry name" value="PI3K_accessory_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057754">
        <property type="entry name" value="PI4-kinase_beta/PIK1_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049160">
        <property type="entry name" value="PI4KB-PIK1_PIK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048:SF22">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 4-KINASE BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21245">
        <property type="entry name" value="PI4KB-PIK1_PIK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11522">
        <property type="entry name" value="Pik1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00915">
        <property type="entry name" value="PI3_4_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51545">
        <property type="entry name" value="PIK_HELICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PIK helical" evidence="7">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="6">
        <location>
            <begin position="690"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="174"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="458"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="189"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="238"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="271"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="507"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ25041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="996" mass="109949" checksum="6496B58950CB5CE3" modified="2011-01-11" version="1">MSWDLLKRFLESDVFNSNPFLSVSYLSRYADHVGIHYVLCNKLRQFPYEDIEFFLPQLCHLIISVDNESMALEEFLMDLCEESVTAALLTFWLFQTYLHDLSSNPQSKSFQTCRRVYNKVQHIVFGLPDAARHDKIKENILPVTVLASFVLASVAVPIVPQWAGPLAVAQARKPQPSDDLISDSRDSNLKTTQVTRAHTVTAGSSRSKRAKDAGRLSSAPDLVLPSSASGNSHHRSTDPSITRPGSSGSKTPVEAKRLPPHLNMKSDDARLSSSSLPLPELRSPRLAITRPTTPVSAGLPPRPGDTLNRRHSHHFKSGATAAELTPLQKTRLLRQHYFRCETQFLTALEGISNRLVIVPKPARLSALRAELALIAQDLPAEVDVPVICPPTLVDGSPAKSRHHRIVRLNPTESTVLNSAEKVPYLLMVEVLRDDFTFDPDTPDNRRLLSTLLSDPGHTRRIFDLSDSPRITTVPKTPEATIDSVFEPVSGDLGSSPLIQPFDEDPLQKPQAKQAPPLQPQRLPSSTTTTMSSVVSDMPTPRSSGASTSRSSSPPGPLRKMTITTRANASVDQPDFSALATHMRTASQMLAQLEATSGKRPKHEVQAIRAKIIASMQSLEEQSFDMDEQGPTFDTIIAKASTAQANAVVNTEHPEVDGEPSVEPGLNAGAGLARMENDIKTGGIQSKGDRDDPSAAVFGEAWQAKKERIRKTSPYGWMKNWDLVSVIVKTGADLRQEAFACQLIDVCHKIWVDAKVNVWVKLMRILVTGESSGLIETITNGVSLHSIKRSLTLSMETGPNQRRRFATLRDHFLKAFGPPDSEPFKAGVDAFKRSLAAYSMISYILQLKDRHNGNVLIDSEGHIVHIDFGFMLSNSPGSVGFEAAPFKLTQEYIEVLGGIGSDDYEDYKTLCKQAFQALRRSADNIIDLVAMMGRDSKMPCYSAGVAQATYNLRQRFQLQLSADEAEQFVETDLIGKSLGSYYTRLYDTFQYRTQGIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3E9</accession>
    <name>E3Q3E9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_00695</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089571.1">
        <property type="nucleotide sequence ID" value="XM_008091380.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3E9"/>
    <dbReference type="GeneID" id="24406060"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00695"/>
    <dbReference type="eggNOG" id="ENOG502S798">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_181109_1_0_1"/>
    <dbReference type="OrthoDB" id="370932at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1050.10">
        <property type="entry name" value="At2g23090-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039713">
        <property type="entry name" value="At2g23090-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039438">
        <property type="entry name" value="At2g23090-like_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007513">
        <property type="entry name" value="SERF-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026939">
        <property type="entry name" value="ZNF706/At2g23090_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33788">
        <property type="entry name" value="OS07G0114300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33788:SF1">
        <property type="entry name" value="ZINC-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04419">
        <property type="entry name" value="SERF-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12907">
        <property type="entry name" value="zf-met2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118359">
        <property type="entry name" value="Expressed protein At2g23090/F21P24.15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Small EDRK-rich factor-like N-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="At2g23090-like zinc-binding" evidence="3">
        <location>
            <begin position="35"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ25551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="74" mass="7924" checksum="A65131326E477EEF" modified="2011-01-11" version="1">MGNGAKAQQKRDRNAKDAKPKGSQLKVNAAAKDIQCQICKATFLKTTKAPALTEHAENKHSKGLPDCFPSFVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q495</accession>
    <name>E3Q495_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alpha/beta superfamily hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_00551</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089427.1">
        <property type="nucleotide sequence ID" value="XM_008091236.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q495"/>
    <dbReference type="STRING" id="645133.E3Q495"/>
    <dbReference type="GeneID" id="24405916"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00551"/>
    <dbReference type="eggNOG" id="KOG4391">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043841_1_0_1"/>
    <dbReference type="OrthoDB" id="10249433at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008474">
        <property type="term" value="F:palmitoyl-(protein) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277">
        <property type="entry name" value="ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277:SF64">
        <property type="entry name" value="SUPERFAMILY HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01760)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ25407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="394" mass="44609" checksum="E83236FFA24C5950" modified="2011-01-11" version="1">MHAIRASSIGQILCRPCRLQALPVIPAWRATSPRLPFPPHLGLTHKRQFQAEALYLPPLVFAGLLVVLWTQKCIAMVVFQNKIIYMPGLPPNARRERIQDYTKQCWGVPWEEKRLQAADGTDLALCVASATSTGDKKPTSHGDTLSVPSIYILYFQGNASSIPPRLPDLSWVLRELQQSKRPARYIMVCLSYRGYWKSRGRPSEKGINLDAQAALHWIGRMHREHDAHGHQPQPEVILWGQSIGAGVATNLAAWEAFPPTARLRSLILETPFTSVKDMLATLYPQKWVPYRHLWPFLRNHLDSWTNLAAIARNWSGKREKPRITIVEAGRDELVPAEHGAKLVQRCEEVGLTVEKKTVRNAFHNEAIFKLDGRRAVVDAIEQVTAEYDCRHGIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4A4</accession>
    <name>E3Q4A4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_00560</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089436.1">
        <property type="nucleotide sequence ID" value="XM_008091245.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4A4"/>
    <dbReference type="GeneID" id="24405925"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00560"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_22_0_1"/>
    <dbReference type="OrthoDB" id="2351791at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF59">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="106"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="234"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="263"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="300"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="337"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="366"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="396"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="506"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="40"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ25416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="559" mass="60223" checksum="7B7E703C2EBBEDED" modified="2011-01-11" version="1">MATAEPDPQGASVVALEKHTTHVDQHGKVVFKPSREFLLAFGALCTIALVVALDATTLSVALPTMSLALGGTALEAFWSGTSFLLASTVLQPTVAGLSGIFGRKSLVFASALLFAVGSVIGAVANDFAVVIAGRTIQGVGGGGIMALIEVIITDLVPLAVRGQWFSLLSAVWSVGTVTGPLIGAGFAQDVTWRWIFWINLPITALGVVMIFFFLKQVGIPGEVSVKLKKFDWLGSFLFTAGSTSFLFGISTGGVMYEWSSFRCLLPLLLGALIIVGFGFWELEFAKEPLIDKGIFNNWTMVANYIMTVFHGMILWSILYFLVLYYQAVKDYSVVISAVAALPESLTVAPAAMVVGIIAGVTGRYRWSLWSGWVITTLGAGLMCLMRPSTTVPQWIWLNIPIGIGTGMLFPAMALSIQAACAPALNGQAAAFYSFLRTFGQSVGVAVSGVIFQNAFRTRLEQIPALADVAEEYSRDATIVVEVIKRMPKGDPMRADLVEAYCDALRAIWISLIAFAGFCMLISVTVKKYSLDQEHVTRQGLVTSDDTSREDVERGEKDER</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q563</accession>
    <name>E3Q563_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tol protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00974</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089850.1">
        <property type="nucleotide sequence ID" value="XM_008091659.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q563"/>
    <dbReference type="STRING" id="645133.E3Q563"/>
    <dbReference type="GeneID" id="24406339"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00974"/>
    <dbReference type="HOGENOM" id="CLU_002639_5_6_1"/>
    <dbReference type="OrthoDB" id="4851591at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF10">
        <property type="entry name" value="TOL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="401" mass="45662" checksum="49455CC67BB154CB" modified="2011-01-11" version="1">MHNVYQHGLCNIMAASAGNSSEPLFNKRDVRLITPCIIPGTDSDNMSTYVQGLEDINEEGKWFEQLSAEPLYRRGWVLQERLLSTRSAIFTRQNVYFQCPHDITRQVHPDNNSADLYFEFSDPRMIPSKFTPETCFETWRLIINAYAKTNLSFATDTFYALGGLAERVRQLSGSKYLHGLWEADLAKCLAWWDETHERRPGIEAPSWSWACVRKPQYFDFTQTEAIPRTWGTMTDGILGLQGPMFSISTESPASNFDPDMVQKEIMRRVEGVADRCDSVAQFDGPETEREDKPVPGDLLCVLLTRSHCRPEYMGILLAPVSVSDTTAPYRRVGFFRLDLSYNGTPSHVDTNVGWAPEIKKRGREFLDECYERLLETLKTQPKDAHGLPCDGATDEQTIFLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q578</accession>
    <name>E3Q578_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Geranylgeranyl pyrophosphate synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00989</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089865.1">
        <property type="nucleotide sequence ID" value="XM_008091674.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q578"/>
    <dbReference type="STRING" id="645133.E3Q578"/>
    <dbReference type="GeneID" id="24406354"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00989"/>
    <dbReference type="eggNOG" id="ENOG502QRQN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030046_1_0_1"/>
    <dbReference type="OrthoDB" id="5393654at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35179">
        <property type="entry name" value="PROTEIN CBG02620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35179:SF2">
        <property type="entry name" value="START DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="458" mass="50910" checksum="A3017542F3098251" modified="2011-01-11" version="1">MYRQNKYNQFQSKPRWRQPEPETPSPAPPFGSLVETVDMAELSVTAAKFEASAQVTSCEVVASYNWLDKTAPSVLIPGAPPRWTPVAKPRPLAEDSGVYYRDKNAARYPAHPMEPTALAVLTMHPEPFKKPVDIVGCGSTIGNLLRFVRGEERPFRMLVEVVGGVVHLIRRENSPTETIPSVRGYGHTFPEAYTTWDAGVRGSASHQRVLRYNFGGLSCVVRHEGDGYLADKLGSLSDGGGAVANEKWSVDSLIQGLGASEMESKSPSHSSPLSSHPGGFQVPQAAVFDLKTRSIFRKGKDFLAEELPRLWVAQIPNFILAYHQRGTFTEIEVMDVSEKVKVWEKSMQRELSQLAALLHRIVSLAHASRDGRLEVIRQEASTLQVREQCPELPLAFSDDMMIKWEDWLALDAKSKVSGAERRADDLEKEAEDDFAWTVGDDDYTACSENCSYCGKCTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5L5</accession>
    <name>E3Q5L5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ubiquitination network signaling protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_01126</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090002.1">
        <property type="nucleotide sequence ID" value="XM_008091811.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5L5"/>
    <dbReference type="STRING" id="645133.E3Q5L5"/>
    <dbReference type="GeneID" id="24406491"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01126"/>
    <dbReference type="eggNOG" id="ENOG502QSPS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005822_1_0_1"/>
    <dbReference type="OrthoDB" id="4158994at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="169"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="384"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="572"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="833"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="953"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="604"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="56"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="106"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="982"/>
            <end position="996"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ25982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1004" mass="109776" checksum="DF8231D68DC69651" modified="2011-01-11" version="1">MPRASNSSKRQQGAANQRDTRHENGLVGPTKRVTNKKSQPNLDAAPSVRNPSDQNAAASALPSSLPNGNGSPNGKLKNPPLAAAHDTMPPDHRNADAVAPAARRPSLGGCSETSSSDSLSSGLLNAVVDASHRQIDVNATKNADVHRDPGGPVEFAATVLRALPLYDTLAILILLMQVPPVALSGIYMVFTFLTFVPPVTTSSGMNINLAEIFDYNSTMPSLVTVLCMDVFILLVWLFLWPTMQLAILDFAKPVIAATLGGGSNTREGASRSVTTCFFLVIGSHLLRGSRFHWSRAAKFLPANWRFSPDPDDPLESFARGFDKRGPHGWIKSVLAIHILTQGIVRYIREWYLRREKGSASTQSITDPEAGKSYATDAAADTGFATPDSDTTFQQNATVSSTKKKRKQSTQVRLQQPLWAALASTKIVMVKEYELSHATSESAGSNATDIHNLGNAPFDSQAEQIWISYIGHDEVCFNTSHFPDSPSAAPNGHVSRPAGVDTSKPFYVRVNNAFWQPTRIFRIQDDEQDEQPGHHRWCGDIYGLRPLSKYVCEFVDTRTNRVIFSTSIRTSFAQNKDQEGSANPPVSTPQSLRPDSPATTLKSTINANNERLAEEKSRLKTLRKEWKNKISSLKKENERLDNVIQSAGGNDDKHRQKIIQQENTKAQSEKEIAQLEADLKAFETAPEGFYERKKQAEKEWSAEKAVFDAASKEFKEHKTSIAKAVKAKEDEQASLQTKRNKIAARIAKVDNELGRITDANNRGLDEAERRRQARGVWQAETATIENNFRGSIADIKAANALKQEQVNALLQQLQAYHEHMNYATATTMPFDIPEQQHHHHHHPHHSPAPQTTMSAYNPAAPAWTQPPPPPPAAAALTSQYMMPAASMWPTSMMTGSGSALPLPTNSTQAVWGYPPPHHSTVSLKARGRSSSMLSDISGFTQSSNGDDEYLSMHNTPAQKPMAQRTPVTFALGRRQRSDGAGSGSSSVRSGSASGSGSTRDPQSPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5Q9</accession>
    <name>E3Q5Q9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_01694</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090570.1">
        <property type="nucleotide sequence ID" value="XM_008092379.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5Q9"/>
    <dbReference type="STRING" id="645133.E3Q5Q9"/>
    <dbReference type="GeneID" id="24407059"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01694"/>
    <dbReference type="eggNOG" id="KOG1430">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045030_1_0_1"/>
    <dbReference type="OrthoDB" id="16464at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050177">
        <property type="entry name" value="Lipid_A_modif_metabolic_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43245">
        <property type="entry name" value="BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43245:SF11">
        <property type="entry name" value="LD23561P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="375" mass="42490" checksum="5B3308E2EDD24866" modified="2011-01-11" version="1">MAEKPSVLIIGGLGYIGRFLARYIHDNDLASEVRVVDKALPQLAWLAPEFQDACAGTKFMQADASREQALAKIFDRPDGKQWDYVFNCGGETRYSQEDEVYKLRSLGLSLAVGKEAAKRKAKAFIELSTGMVYKSDSSPSKEGDKLKPWSKIAVYKLQAEEELAKIKGLNLVIVRLAHVYGPYASQWVATALCMARVYQYLESEMKWLWDKGLRQNTVHIQDAVRALWDITTWYDKGKDKWDDKTMGRVPTFNVVDKGVTTQGTMAEIIGEVFKIETGFQGQLISTFARLNMDSVVDDVNDELMGPWAELLEKAGIARPGPLTPFMEKELLKDTDLSMDGSRLEQVVGFQYEKPKLTKELIEEVIESYKKMNWWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5W1</accession>
    <name>E3Q5W1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">BZIP transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_01353</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bZIP family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090229.1">
        <property type="nucleotide sequence ID" value="XM_008092038.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5W1"/>
    <dbReference type="STRING" id="645133.E3Q5W1"/>
    <dbReference type="GeneID" id="24406718"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01353"/>
    <dbReference type="eggNOG" id="ENOG502QVAF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017851_2_0_1"/>
    <dbReference type="OrthoDB" id="644067at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47416:SF8">
        <property type="entry name" value="BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTOR E-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47416">
        <property type="entry name" value="BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTOR F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="8">
        <location>
            <begin position="248"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="261"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ26209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="609" mass="67579" checksum="7AD95A8CCC3A0AB5" modified="2011-01-11" version="1">MVSTYQMPAYYRSTPLTVDTTQAQKYYEEEDHSILDENILDHSALDSGLEMSPPMAGSRRESFAVGGSLFSPKTEDWQSVDMQSVPSNNPFMEQHNNNPFMRLDHAQPSPFGHQGNPWSLSNTSGSCTPLQQFDGMPAEYDNSTPMFQRPVQGQTPFTNPTGQINMFAPIGSGNQSIPTSPQKGWLGQAESMAKKMRPGSPAIRSHNDMRRGDGIRKKNARFDIPAERNLSNIDQLIAQSTDEQEIKELKQQKRLLRNRQAALDSRQRKKQHTERLEDEKKQFSAVLTDMEEEMAEMRKQMEQLLREKQFNQEYIESLTMEKEEMIRAHTIETGELRKKVSVLTDHVQRLENAAMTAPSNNAFVSSYDDMDGMTMPGTWDNVNFLGEYSMEQEVKQELQVVPTKKAEASFPAESEKSSSQGGILFMLFLVGAFVLSSRSTPSIPRVSEDVRAEAATLLENVFKDAGINEASNTMNAVAPQPSGGSWVDNSAVSMGDTSMGGVVPSMLGQLGDSLTQPTDEQANEQLFGLSAAQYNGVNSQDFLNNAPERSTSQGRKNLADALAAMRSTKQSAAEVYTRSLLWDQIPSEVVRNFAKMVSEGNSAKAGANE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5W3</accession>
    <name>E3Q5W3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mob1/phocein family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_01355</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090231.1">
        <property type="nucleotide sequence ID" value="XM_008092040.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5W3"/>
    <dbReference type="STRING" id="645133.E3Q5W3"/>
    <dbReference type="GeneID" id="24406720"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01355"/>
    <dbReference type="eggNOG" id="KOG0440">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038321_0_1_1"/>
    <dbReference type="OrthoDB" id="10261121at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.30">
        <property type="entry name" value="MOB kinase activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005301">
        <property type="entry name" value="MOB_kinase_act_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036703">
        <property type="entry name" value="MOB_kinase_act_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22599">
        <property type="entry name" value="MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03637">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01388">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101152">
        <property type="entry name" value="Mob1/phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="17"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR605301-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ26211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="340" mass="38037" checksum="46F44BE6D9E77830" modified="2011-01-11" version="1">MNSNARFRGQAAKPPGSNKSPTSSTAGQQPTSPTVSHGSQPSTNNAPKVPPLPNSPSLAHSIGMDDQGSLTDGDSILNSYHLPRPMPIWLNSNYGKHIVKGNFMTLSARPKTVEQGEWIAHQVVEHYRNLWNFVRVLHEKEEDGSTICNATTCPRMSAGANHSFTWLNSRREPVELPAFEYMTLMQRWISGKIDDTNIFPTDPSGVSYAHNPAITTTPLSQLTNPGEPDWIGKRSGFPQNFIDVCQTIFRQMFRVYSHLYWAHFVEPFYHLNLEKSLNSCFSHFILTATALDMLKPHELEPMQPLIDLWAANGTFPPESKAYEYANLRAGERLMQLAGVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q659</accession>
    <name>E3Q659_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_01451</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090327.1">
        <property type="nucleotide sequence ID" value="XM_008092136.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q659"/>
    <dbReference type="STRING" id="645133.E3Q659"/>
    <dbReference type="GeneID" id="24406816"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01451"/>
    <dbReference type="eggNOG" id="ENOG502RZZS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038616_0_0_1"/>
    <dbReference type="OrthoDB" id="5578001at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="400" mass="43795" checksum="48A7CFD402FA0F40" modified="2011-01-11" version="1">MTSTSTTPMPNIGGLLAPLLPALVPASISTQPAIGVLPLLSPILRQRVQLLSESSTEPWLRLLAYHTDKAARLLEIVQSGRLEPHPVSGEVEVDWEYDAKTRYRRLDLETLQAFVALEELELTFQLIYCVGDKDGGGDGWRIGEVSVIDKAAAPFGTFGGYSTIAEAEKAYADEKSKTSVSKAPASVSHNHVPEAEEEEDDGYWDRYDATPARTPANDSPATKRSPAPHVHRPSQLGQFRADSAEDAYYAQYDSVQPAMDAHDPDEEVEGFDVAPPLGLGTVVNRDNSDKGLVETNGSWTLAEAPRSPSIRSQQDEDRAAVLLHPRPASSASSNGSRLVEKLEESVGKQDQNEFGVKQHVSRSIHNLFLLARSSGIDREEFERLVKTELDVLGMIEENEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6F5</accession>
    <name>E3Q6F5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_01547</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090423.1">
        <property type="nucleotide sequence ID" value="XM_008092232.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6F5"/>
    <dbReference type="STRING" id="645133.E3Q6F5"/>
    <dbReference type="GeneID" id="24406912"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01547"/>
    <dbReference type="eggNOG" id="ENOG502SP89">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_844707_0_0_1"/>
    <dbReference type="OrthoDB" id="6359816at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843:SF6">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="72"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="170"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="229"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ26403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="329" mass="35548" checksum="AFA059E58B6B7C58" modified="2011-01-11" version="1">MSVDGRGHSGGRAGDSADGASRTLGDVMRSGPTMSPGIVVVDQAYEETKRKDDLSPSEDLWLSSADGRYNSAIIPLRVGRAPSQEVFYVHRDILLTTEYFRKALCGDYRESEAQSMEFPEEDPAIFHFLVAFLYQRSFVPIRPAASALDTKEPHRGKAQDPGHRSDSESEMSSSEASDASARSRMPALHHHQHRAAMLELWRQSREADTRPPPAAHDHPDTPIKAGGDAATAAAASPTSQSAALGTSTPANADFMDGDRIRGEDMRTWLAIYDLSISVYACANKYLMDDFKAAIQRHCVDMLESAGSDAAQSTVLQLSAAVAAGTAAHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q722</accession>
    <name>E3Q722_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Metalloprotease MEP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_02480</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Secreted metalloproteinase that allows assimilation of proteinaceous substrates.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M43B family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090680.1">
        <property type="nucleotide sequence ID" value="XM_008092489.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q722"/>
    <dbReference type="STRING" id="645133.E3Q722"/>
    <dbReference type="GeneID" id="24407845"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02480"/>
    <dbReference type="eggNOG" id="ENOG502T46Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048726_0_1_1"/>
    <dbReference type="OrthoDB" id="536211at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008754">
        <property type="entry name" value="Peptidase_M43"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47466">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47466:SF1">
        <property type="entry name" value="METALLOPROTEASE MEP1 (AFU_ORTHOLOGUE AFUA_1G07730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05572">
        <property type="entry name" value="Peptidase_M43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 13" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3 13" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178249" evidence="11">
        <location>
            <begin position="22"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M43 pregnancy-associated plasma-A" evidence="12">
        <location>
            <begin position="160"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="281"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF05572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ26660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="307" mass="33583" checksum="3BC9FD23A2F8B06F" modified="2011-01-11" version="1">MCHRTWARLLGVALIASVALALPSRGHTLNETPHGRPQQSQSWCSFGEYAAPLNISDDLEALERATSESPADQGATINIPVNVFILGNPETQSKLNMTSPVVRLQDSLAYGYSSLGYSFGPFNTYHIYDLEFAEFEFDTLVSHKLLKMAWRLRTGGAETLNIYLVPKMAPGLLAFALFPRILMKDSRNSLALDGVLFSHHTMTHFLSEKTTIHEVGHWLGLTHPFQGGCLVPDGDGVPDTPQTDFKGDQECAAEKDTCPNLPGIDLYPELNFYSGPNLEDAPVLEPISKPQDPAASSLYKPASPDGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q739</accession>
    <name>E3Q739_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">O-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_02497</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090697.1">
        <property type="nucleotide sequence ID" value="XM_008092506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q739"/>
    <dbReference type="STRING" id="645133.E3Q739"/>
    <dbReference type="GeneID" id="24407862"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02497"/>
    <dbReference type="eggNOG" id="ENOG502RXVR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069348_2_0_1"/>
    <dbReference type="OrthoDB" id="203237at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007213">
        <property type="entry name" value="Ppm1/Ppm2/Tcmp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016874">
        <property type="entry name" value="TcmP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43619">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASE YKTD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43619:SF2">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04072">
        <property type="entry name" value="LCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028177">
        <property type="entry name" value="Polyketide_synth_Omtfrase_TcmP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ26677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="292" mass="33409" checksum="364C2C955321EAE4" modified="2011-01-11" version="1">MASGKKTKPTLTGVPETLLGTMVSKAIDAASPSPILRDTWAAEMVTRIDYDFDRLEVPGWMQAWAVLRSRDFDRWTSEFLDLHAHSPNGATVLHVACGLDTRALRLRQYFSRMPLRWIDVDLPDVVELRKELVPDPLVNRNGSTYEMQALSATEAGWYRDIPADRPTVIVIEGLSMYLAEEEMRQLVHGLVDHFRQGQHQHGHLLFDATNSFVMAAQGWLKPIVKSGSRFNWGLDNPLSIEAWAEGLTLREELLLTGRPLIKELPWRVRVQFAVAASLPWFYDFQRMMRYSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q747</accession>
    <name>E3Q747_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02505</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090705.1">
        <property type="nucleotide sequence ID" value="XM_008092514.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q747"/>
    <dbReference type="GeneID" id="24407870"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02505"/>
    <dbReference type="eggNOG" id="ENOG502RPKN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_454146_0_0_1"/>
    <dbReference type="OrthoDB" id="4588713at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="605" mass="66194" checksum="4AF9DCA3EB2CFBAC" modified="2011-01-11" version="1">MDHLSSCSSSTGTATYTRQSVSTFQQDAPKQTYTTAGTIYNPSNSQPLQPPVRRGRALKWPPVGAAASELSLFPKSVLAGLPLKSQSLTPKSTSPLPHQIPKYSPLQQNYDRAISPVTDNSRDSPNDSDVSSLPSSRIPSYTMNSSQVSPVDGVMSTPAVGKRVDIESSDDEDEESTGENPLKNFTVKGLQNLASYPNPNQKRAQKTLLRARPGATPVSSTGNVNHTATPSYGTQFFDTPDMVKNDSISPGLFHSAKTDPNAVLKLQVDQRPIRDLDISWRANDATPSPPPCLFPAHNVQRSIPHSTYKSTLATGPGAPRPLTAGPPGQRQYRTSTFDSNMKMLNCGSKADMSYDGSVNDDIHPPANAVQNNISLSALRLAGSDTPDQLKSGLHSLLCTSTPDTDYSYQGSVEPGKLSDVDMKKILQYINLGPAADTNANDCKHGYRQPEPNLHVTFGESWLADYPKTDRSRLTKGTWTIAEDELRRRVERINQLFYAGTGELGKSFESVVKDAEFNNFKRQVGVIGDRRPKAKLEKVEHTPISIRQANNMTNKEAAEPLVALGVSSVLNHIEGKYHSPQFYQWEDPETSKVDESVEGRKSVFRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7X4</accession>
    <name>E3Q7X4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">PX domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_02157</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Essential for proper morphogenesis of the vacuole. May exist as structural reinforcement on the surface of the vacuolar membrane and be required for maintenance against rupture by osmotic pressure.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ26986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091006.1">
        <property type="nucleotide sequence ID" value="XM_008092815.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7X4"/>
    <dbReference type="STRING" id="645133.E3Q7X4"/>
    <dbReference type="GeneID" id="24407522"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02157"/>
    <dbReference type="eggNOG" id="ENOG502RXJQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033748_2_0_1"/>
    <dbReference type="OrthoDB" id="428895at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097576">
        <property type="term" value="P:vacuole fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06897">
        <property type="entry name" value="PX_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15858">
        <property type="entry name" value="SNARE_VAM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1520.10:FF:000052">
        <property type="entry name" value="Putative SNARE complex subunit (Vam7)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000058">
        <property type="entry name" value="VAM7p Vacuolar SNARE protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22775">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22775:SF3">
        <property type="entry name" value="SORTING NEXIN-13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0926">Vacuole</keyword>
    <feature type="domain" description="PX" evidence="7">
        <location>
            <begin position="3"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="6">
        <location>
            <begin position="304"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="238"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00054927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ26986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="366" mass="39694" checksum="933258DFDE65F64D" modified="2011-01-11" version="1">MAPPAEISIPSTILSTGESKPYTLYNITLRLPLKSFVVQKRYSDFAALHQTLTSLVDSPPPKPLPAKSWFKSTVSSPDLTEQRRQGLEAYLRAIAESPDRRWRDTTAWRAFLNLPSTGVGSTSNSAASAHGLITSGRAGAADPTTWLDLHREMKTCLHDARNQLARRDGAVDSNNSTAAAEAGAAAKRSLVKAGTLVNTLTDGLRAMQEGGRLGDGELRRRRDLLSSARVEREGLDKLSNSMAQGTSRSGGGREGWASVGDKAALLGGNRNGGARTGGRVLGAPLPENERTRELDNGGVVQLQRQMMSEQDEQVNTLAAIVRRQREMGLRINEEVQEQTKMLDRLNEDADRVGGKIDVAKKRVGKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8F3</accession>
    <name>E3Q8F3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thiamine-binding protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_02336</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0045 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091185.1">
        <property type="nucleotide sequence ID" value="XM_008092994.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8F3"/>
    <dbReference type="STRING" id="645133.E3Q8F3"/>
    <dbReference type="GeneID" id="24407701"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02336"/>
    <dbReference type="eggNOG" id="ENOG502S45I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_137479_0_0_1"/>
    <dbReference type="OrthoDB" id="5587367at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.930">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029756">
        <property type="entry name" value="MTH1187/YkoF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002767">
        <property type="entry name" value="Thiamine_BP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051614">
        <property type="entry name" value="UPF0045_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00106">
        <property type="entry name" value="MTH1187 family thiamine-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33777">
        <property type="entry name" value="UPF0045 PROTEIN ECM15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33777:SF1">
        <property type="entry name" value="UPF0045 PROTEIN ECM15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01910">
        <property type="entry name" value="Thiamine_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89957">
        <property type="entry name" value="MTH1187/YkoF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thiamine-binding protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ27165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="115" mass="12412" checksum="259231EEF2059D80" modified="2011-01-11" version="1">MSSEDYSKIPTPESAYCDFCLIPVGTGNVSVANEVAQVQRLLNASGLKCTMHSAGTTVEGSWDDIFRVIGQAHSLVHQSGVVRIQSSMRVGSRTDKKQSAEDKVKRIEGILASDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8G5</accession>
    <name>E3Q8G5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DSBA-like thioredoxin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02348</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091197.1">
        <property type="nucleotide sequence ID" value="XM_008093006.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8G5"/>
    <dbReference type="STRING" id="645133.E3Q8G5"/>
    <dbReference type="GeneID" id="24407713"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02348"/>
    <dbReference type="eggNOG" id="ENOG502RH77">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069253_1_0_1"/>
    <dbReference type="OrthoDB" id="4664297at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004602">
        <property type="term" value="F:glutathione peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001853">
        <property type="entry name" value="DSBA-like_thioredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051924">
        <property type="entry name" value="GST_Kappa/NadH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42943">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE KAPPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42943:SF13">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE KAPPA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01323">
        <property type="entry name" value="DSBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DSBA-like thioredoxin" evidence="1">
        <location>
            <begin position="162"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="241" mass="26709" checksum="BEFFE25FD06473C6" modified="2011-01-11" version="1">MGGRVDAYLDIASLYSYIAFYHIIKNQELLAAHGVHVDIHPILLGAVNAATGNKPPWSLPAKAVYGSFDARRSSVRVGKPDITPPDNFMESTMTVLPLRALHFIKANYTHAAYLTAWHWLLHRFWEPPNVNLTKPDALAAALADAPRQYPGDTEDRLFSDADVRRILEGAAAQEIKDSVKAKTQEAVERGAFGAPWFWVVNDEGKGGPFFGSDRFHFMYDHLGVPYQDVAILPPQSKGAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9W6</accession>
    <name>E3Q9W6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peroxisome assembly protein 12</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Peroxin-12</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">GLRG_02798</name>
    </gene>
    <organism evidence="19">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Component of the PEX2-PEX10-PEX12 retrotranslocation channel, composed of PEX2, PEX10 and PEX12.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the pex2/pex10/pex12 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091674.1">
        <property type="nucleotide sequence ID" value="XM_008093483.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9W6"/>
    <dbReference type="STRING" id="645133.E3Q9W6"/>
    <dbReference type="GeneID" id="24408163"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02798"/>
    <dbReference type="eggNOG" id="KOG0826">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031067_2_1_1"/>
    <dbReference type="OrthoDB" id="107372at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990429">
        <property type="term" value="C:peroxisomal importomer complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016562">
        <property type="term" value="P:protein import into peroxisome matrix, receptor recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006513">
        <property type="term" value="P:protein monoubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017375">
        <property type="entry name" value="PEX12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006845">
        <property type="entry name" value="Pex_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12888:SF0">
        <property type="entry name" value="PEROXISOME ASSEMBLY PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12888">
        <property type="entry name" value="PEROXISOME ASSEMBLY PROTEIN 12 PEROXIN-12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04757">
        <property type="entry name" value="Pex2_Pex12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038074">
        <property type="entry name" value="Peroxisome_assembly_p12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Pex N-terminal" evidence="17">
        <location>
            <begin position="25"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="302"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="16">
        <location>
            <begin position="305"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="319"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00034505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF04757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EFQ27654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="439" mass="48609" checksum="C31A7CC9D555314C" modified="2011-01-11" version="1">MEFMTALRGSFDDQKPSLFELISEQQLNSLLPPTIRYLLTVATQRYPRYLLRALNSFDELYALCMLVVERHYLKTRGGSFTENFYGLKREKALHAEIPRASAAAPGVVRDTLKLGTKDVWMNLAVVVGIPYLRRKLDEGYEVNAPRALLGAAYTQMPPNPTTKQRFLHYYRWFLRNIYPSVNAAYYFALLSFNLAYLFDNSKYHNPFLWLIGTRMRRMTGADYHAIDALTSGKPSGGRAGAPPGWRSLLSPREMGPRLLSSLSLLLPMSIFALKFLEWWHASDFAKQLSRKATETLDLPPPVVSGLGGGKGGAGAAKSGAEKGKEKATAGGSDDDKTAVPAAEMAPIATPSLLPIYTVPAPKDSSLCPICKDAIVTPTACQTGIVYCYTCIHRWIEGLHPMQEDFMGDKEGKWESGQGRCAVTGRRVLGGTEGLRRIMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9Y9</accession>
    <name>E3Q9Y9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ATP synthase regulation protein NCA2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_02821</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091697.1">
        <property type="nucleotide sequence ID" value="XM_008093506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9Y9"/>
    <dbReference type="STRING" id="645133.E3Q9Y9"/>
    <dbReference type="GeneID" id="24408186"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02821"/>
    <dbReference type="eggNOG" id="ENOG502QTT6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008227_1_0_1"/>
    <dbReference type="OrthoDB" id="413313at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013946">
        <property type="entry name" value="NCA2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28234">
        <property type="entry name" value="NUCLEAR CONTROL OF ATPASE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28234:SF1">
        <property type="entry name" value="NUCLEAR CONTROL OF ATPASE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08637">
        <property type="entry name" value="NCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="544"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ27677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="669" mass="74788" checksum="69865FCEDB006632" modified="2011-01-11" version="1">MSVVADQVRRLDAQLDRIPLGLSLSQDDGELSAEEHGIFNSAAVDAFSSPRIDELLRIARALSTTSSSLSLLPSHRIHALLHQSKLAEWDFHAEQNEGAGRGHYQSEIEWLLISKATVQTYGIILNVLLDQIIPLSDEMWYWDEVLSSYTYSSLYTVQTSPLRLWALTKDVYRESKHRIQNLSQTPGELVESTRIGLSDRWKQFYGIVRDSIRDSSITTLQRKVLSPVALSRGEARRKLAHLRRLRDMIASGLGVLVDEGLTFGGDDDDDKSEAGVSSHDWKGVVERSVALMDMVLKEALVLESGVAEFEDKVFAGVEEDPELSIHIEDANAVEKPSVLARRLLNILDTGLPSHVAAAQMLVRDNGRPSRFIRYWLPATAALLSSTTILRLLANRRAEILGWIQDIGATMRDFWFNWVVEPTRKIVGTIRHDSSSEIAIMSRDSLKADRESLERMVVDFALDKPQFVGNGSSLSDAQIATIRAKVGEGDVTPVLRAFEKDLRSPFVGAVKGDLVRSLLIQVQKTKVDLEVAISGIDSLLKSQELVFGFVGLTPGVLVSIGIVQYLRGIFGARKGARHSHKAGKSIRVLRNIDRIFSEATPSQNNLLSYKDHGLLLCEVHVLRSLMQGVLPRDRQREFLEDLDDLANLKGIQVQVRALDRIRWAYARWLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAH5</accession>
    <name>E3QAH5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Short chain dehydrogenase/reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_03007</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ27863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091883.1">
        <property type="nucleotide sequence ID" value="XM_008093692.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAH5"/>
    <dbReference type="STRING" id="645133.E3QAH5"/>
    <dbReference type="GeneID" id="24408372"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03007"/>
    <dbReference type="eggNOG" id="KOG1205">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040671_0_0_1"/>
    <dbReference type="OrthoDB" id="1933717at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051911">
        <property type="entry name" value="SDR_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976:SF16">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="358"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="368"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ27863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="379" mass="41512" checksum="0D87F73BB2409001" modified="2011-01-11" version="1">MVDRKGTEAAAKHSYSIPAPSFPTHNSPRTWFLTTALSPLIIRLIRLLLAHGDYVVACLPPSEIEDDGRSAEFRELIDECKSNRKDREGWKDRIRGIRCDGRVMGQCGAAVAEAVQVFGRIDILLCCRSEAVVGSVEELSTTPQTQNLVRDQFETIFFSQVNFIKAALPLLRSQHTGHIMILSSTGGHLGTPGMPIYTSAIWALEGFCDSLAYEIAPFNIKVTIVQPNKEIQSLTNKIIFAPQLPWYDSEVNPAPSVRDMLGNLLNMNPETAMPDPNETDEVQVRYPKLPPSATDRLVMETVHALTAIGGHENPPARHIVGFEGAAAVKEKLKTVTEELEDFVDASLSVDIFDSELKAEAKEGKTTESPPPAPPSIASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QB35</accession>
    <name>E3QB35_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA N(3)-methylcytidine methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_03217</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">S-adenosyl-L-methionine-dependent methyltransferase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the methyltransferase superfamily. METL family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="4"/>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ28073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092093.1">
        <property type="nucleotide sequence ID" value="XM_008093902.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QB35"/>
    <dbReference type="STRING" id="645133.E3QB35"/>
    <dbReference type="GeneID" id="24408582"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03217"/>
    <dbReference type="eggNOG" id="KOG2361">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029724_1_1_1"/>
    <dbReference type="OrthoDB" id="417697at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052735">
        <property type="term" value="F:tRNA (cytidine-3-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000221">
        <property type="entry name" value="Methyltransferase-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026113">
        <property type="entry name" value="METTL2/6/8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22809">
        <property type="entry name" value="METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22809:SF11">
        <property type="entry name" value="TRNA N(3)-METHYLCYTIDINE METHYLTRANSFERASE METTL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037755">
        <property type="entry name" value="Mettl2_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 12" evidence="6">
        <location>
            <begin position="153"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="33"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR037755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ28073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="350" mass="40252" checksum="B16663E9492A9205" modified="2011-01-11" version="1">MASLAVGKALPGADEQVLIEKTADLQVSAPTGQEEKLPHRSHDPQYNQKRSDPFQFGSRLLGEQDDVFEFNAWDHVETDDAYKEYAEQQYEMQRQSPVSDFDKNRFNNNPARMWDLFYKNNTANFFKNRKWLQQEFPILSEVTREDAGSVTILEIGAGAGNTAFPILASNKNPSLKVHACDYSKQAVEVMRTHESYNQDHMQADVWDVTSDELPPGLEEGSVDVAILIFIFSALAPSQWNKAVSNVYRLLKPGGQVCFRDYGRGDLAQVRFKKGRYLDENFYVRGDGTRVYFFEMDELEQIWTGKSQETSEGTKAEFIVDDLGVDRRMLVNRARKLKMYRCWMQGRFTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBH1</accession>
    <name>E3QBH1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_03454</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092330.1">
        <property type="nucleotide sequence ID" value="XM_008094139.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBH1"/>
    <dbReference type="STRING" id="645133.E3QBH1"/>
    <dbReference type="GeneID" id="24408819"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03454"/>
    <dbReference type="eggNOG" id="KOG4177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055162_0_0_1"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF5">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ28310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="305" mass="34800" checksum="25E72E3C70F0FCD0" modified="2011-01-11" version="1">MFRSLLLQLLEGYRDLQTVLGDPDIVPRTQRGCPSLNTLKDIFAASVSRLGSRTFTCFVDALDECDEQQVRTMVQDLEELADESKEKGQVLRICFSSRHYPYINIRHGIHLTLDGQSGHVNDLNNYVRSRLDIKDPKLVNELQGQILEKAAGVFLWVILVVEISNKENGRGRLALKKRLEAIPDELSELFKNILRRDNQNMEQLLLCVLWILLAKRPLRPKEFYHALWSGLSPQGLVDDEVPDVTSQDSGDTFTSCVVSYSKGLAEITKSNQPVVQFIHKSVRDFLVKDKGLQEIWPDVGYDWEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBL9</accession>
    <name>E3QBL9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_03502</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092378.1">
        <property type="nucleotide sequence ID" value="XM_008094187.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBL9"/>
    <dbReference type="GeneID" id="24408867"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03502"/>
    <dbReference type="eggNOG" id="ENOG502RNUW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010623_0_0_1"/>
    <dbReference type="OrthoDB" id="4844686at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="475"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="585"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="654"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="678"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="897"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="979"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="422"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="495"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="607"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="654"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="679"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="705"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="732"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="756"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="902"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1026"/>
            <end position="1035"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ28358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1075" mass="117069" checksum="BAB9B8A3791AC194" modified="2011-01-11" version="1">MDPLELELHTGGSDNPRAPPQPCILDRKRPVARFPETFSSNLGRKASSFFSQEDSASGVDKNYPSPPPIPESKSVLHRKRDIISGLPSPQPLPRNRQLSTVSSVKAMVAKFESVGDALEKSDKMADHEDHHLIPSSPVVDKHKDKASFADDADTSAASPKNCQPSNIGEGKSDNSDVDLEFLKMQDFFKGEPLARCLEDYIPPTYIDKKTKILSPEKDCGKSMEKAAKVELWNKLASLTDTLEAQYPSVKEEREAKHAVISAAAAYLEEALGESPKKLPQVDAAQTSTKASRRAEKKAQKKADKKAQKAAKLDSSIANTLEAASSSMTKQAARDEPSLREKYPEIFAKIDYWRSLPDPDAPADVDGDYTSIADIDSSQSTGQPISQSINQLVSETVVEEAQSIPKQHHNTLSTKTEDDKTIANDSSESDNWSTGSSNGDPFYLNKYLTPSYQAAAKVFLEDFDRKNPTQPITKSIVQQAPPEATEGEESFQFVQRDPKELSDAEETKKDKAIDAAEKKATELNKRPHERVDAAHADGNIAHFVNYKSVRDAIGTNIKKEDIVPGFGQKKQPAPDFDEEAYATRSIASHTLKPAPLRLPSRMKKPVTGNDTTNVKSTTPTQAETPLPPGALLVNTNKYRMVTGDFATLGVGFGKTSNRIASGSSTHSTRGAVNFSWPKAQHADAKNKYEFNDEDDSDYDIDKKSNTVPTKLNTSARNTDSASVHPRIVSAGGRAREMRKDGDAFDNKSTHGHHGSAASITAQSKGSSQKLSYTSAQPNTTSAKGNYEEAQRRSFTADEYQTLIQEDYDAFAKDSPEKKQKRLEDAMAGLKTGSTMGTTEVTSDITHQTVIVPANQQGFTIRLPGATALPPTPATSHAPMTTGEKMAELDDFFSEENDHRYKTTRTQTGSTYSSDYGDGAGTSVQDQVHEQPWNDANYDEEALSYGYAYKQTNYHTLPHSVNPVPLTHEQRHQVLKSYGIPDEQYSAPPTGYPNPPGPDKGSKAPPCPIRAAPVAPTTLSAAGGGGDGADRRVERSSADGGAAVESLRKHRRFRRAATAPPAPAPVSPAPGYDDDWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBQ6</accession>
    <name>E3QBQ6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_03539</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092415.1">
        <property type="nucleotide sequence ID" value="XM_008094224.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBQ6"/>
    <dbReference type="STRING" id="645133.E3QBQ6"/>
    <dbReference type="GeneID" id="24408904"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03539"/>
    <dbReference type="eggNOG" id="ENOG502SIPI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015774_0_0_1"/>
    <dbReference type="OrthoDB" id="415825at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540">
        <property type="entry name" value="TRANSCRIPTION FACTOR (ACR-2), PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540:SF9">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="82"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="562"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="755"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="82"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="583"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="770"/>
            <end position="787"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ28395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="795" mass="85810" checksum="8A022F8B16B9C159" modified="2011-01-11" version="1">MQCDQEQPCSNCLRRFPVPICEYRAGNRIPGTSTFLAPARARGRVPIHLPLPGADSPLVQVSQSPRTAGHSPISVAGWVASENTTSNSSPKTDCLTDPAASDAPWPQSDSLDESKRAAAAVTAPAPWLPLADPQRSILDSDVSQASQQMLAYRLAVPGLVLNLADKDGVGELDGDGDDNEQNNHDNKIFVAGESIPRGWHHAEKPRVQRPERPISAVDAEIVHLPVAQTVLNKKLLRIYVTVLSRFKASVNGDPDPNNPFMRHYSPFCLQDPLVVQIIFYTSGCFLHETGHVRTTVLRTLKGRAIHMLNESLMSHGADGRRHSNGQDTAETALTTMTTGSSGRSEHPSDAAIAGVIQLTVTEWYWGETEDDLRYHLKGLRGMIRLRGGFNQLGMNGLLAKNAIVHDVSISLAHENVPLLLTPPPSDALATTADPWGPTGYTFDDPIKHVPLRMAHMSPFVSHLPSSVGVLPSFANCAASLGMHSATASILDNVRYLVGAVEAIYTAANETNTTNTIMTETTTKAMQASRKAQLTGRYMHEHISGLHSTIPGFRQFLSPEEIPIRARPPPNSSIHTTVEEASEESGNIFSTSTVGRGSVGAGRSPSGPSSDSEWLQRRDVGDSPASPRSTQYGHHRQHPQQSPDFMYQVVRMTAIVYTRAIATGTPLSGACTESEFLQIWTTTWRVPLSTWNSAVGVFHWIMMAIAPACHRTPHARFVKNMTTISTLTLGVENWAMAMSAARAALRLQHWLGGQQDTKGAGKRDGAGAEVAASASTTARGAAGSAAGGQCSRLEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCC6</accession>
    <name>E3QCC6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Endonuclease</fullName>
            <ecNumber evidence="17">3.1.30.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">GLRG_03658</name>
    </gene>
    <organism evidence="22">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2 17">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 17">Belongs to the DNA/RNA non-specific endonuclease family.</text>
    </comment>
    <dbReference type="EC" id="3.1.30.-" evidence="17"/>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092534.1">
        <property type="nucleotide sequence ID" value="XM_008094343.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCC6"/>
    <dbReference type="STRING" id="645133.E3QCC6"/>
    <dbReference type="GeneID" id="24409023"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03658"/>
    <dbReference type="eggNOG" id="KOG3721">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055174_0_2_1"/>
    <dbReference type="OrthoDB" id="5418055at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000014">
        <property type="term" value="F:single-stranded DNA endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006309">
        <property type="term" value="P:apoptotic DNA fragmentation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00091">
        <property type="entry name" value="NUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.570.10:FF:000004">
        <property type="entry name" value="Nuclease 1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.570.10">
        <property type="entry name" value="Extracellular Endonuclease, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018524">
        <property type="entry name" value="DNA/RNA_endonuclease_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044929">
        <property type="entry name" value="DNA/RNA_non-sp_Endonuclease_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001604">
        <property type="entry name" value="Endo_G_ENPP1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020821">
        <property type="entry name" value="ENPP1-3/EXOG-like_nuc-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044925">
        <property type="entry name" value="His-Me_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040255">
        <property type="entry name" value="Non-specific_endonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13966:SF5">
        <property type="entry name" value="ENDONUCLEASE G, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13966">
        <property type="entry name" value="ENDONUCLEASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01223">
        <property type="entry name" value="Endonuclease_NS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00892">
        <property type="entry name" value="Endonuclease_NS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00477">
        <property type="entry name" value="NUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54060">
        <property type="entry name" value="His-Me finger endonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01070">
        <property type="entry name" value="NUCLEASE_NON_SPEC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 17 21" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="10 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0464">Manganese</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 16 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="6 17" id="KW-0540">Nuclease</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA/RNA non-specific endonuclease/pyrophosphatase/phosphodiesterase" evidence="20">
        <location>
            <begin position="104"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="ENPP1-3/EXOG-like endonuclease/phosphodiesterase" evidence="19">
        <location>
            <begin position="105"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="29"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="40"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="18">
        <location>
            <begin position="63"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="169"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR640255-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR640255-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU366055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="SMART" id="SM00477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="SMART" id="SM00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EFQ28514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="355" mass="38341" checksum="7F66E7239DCF6B60" modified="2011-01-11" version="1">MSKTTSLALIAALSAGGGAALTATMYSLRSPKQPAPSTTNASPPLNSPSVPVPATQVFTNPSAPLPPAAAAPSPPLPGSVSGNPVDPAGLFEYGFPGPVADLAQRPALISSYDRRTRNPHWVIEHITPASLAQRGGDRKNSAFVEDTSIPEKFQAKLKDYFRSGYDRGHQVPAADCKWSQKAMDDTFYLSNMCPQVGDGFNRDYWAHFEDFCRRLTTRYPSVRIVTGPLYLPKRDPVDGKWYTKYEVIGNPPNVAVPTHFYKVIFAEDGKAGGNVAIGAFVMPNAPIPNNKPLSDFEMPLEAVERAAGVEFASKLAPQRRKRLCSEASCAIVVKEYADRQKSFGKGGSQSRSPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCW0</accession>
    <name>E3QCW0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_03876</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092752.1">
        <property type="nucleotide sequence ID" value="XM_008094561.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCW0"/>
    <dbReference type="STRING" id="645133.E3QCW0"/>
    <dbReference type="GeneID" id="24409241"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03876"/>
    <dbReference type="eggNOG" id="ENOG502RDBT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005788_0_0_1"/>
    <dbReference type="OrthoDB" id="10256176at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF92">
        <property type="entry name" value="METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="3">
        <location>
            <begin position="715"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="54"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="320"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="412"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="8"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="54"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="85"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="100"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ28732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="976" mass="107992" checksum="3982B0094209B7C0" modified="2011-01-11" version="1">MEEESEDTQYATDNRQLRSQTSNLKIEAWLSPLSDHFPTPRGFHFLSAPILPSSPSTISADESSSPSTSSNPWNNNRSSVMTDVTEFDDLYDVTDEDEPPELRRVPSRKDSVRRRKSGRNAVSKKTAAGVRRALPPLVIPGGRNTSTEDWSAASLKKTLASPVPPTPPTRVEMSPQVFSFMQAKQAQEVPTISAPPSLDGSLSSEQLAQMSAPPTPIIGSDDGKEADWSGVRLQPGALATLHALSGDNDSLHEHDHEHSDQVLEIPQEPVPEMRQQPLRLFTNLFAQPARVAELTPSSHRRSLADLTKLDIPSPGGFFSGLSPRTRTTWHMPTRSPEDMVPPTSTTAEQFYRCPWNVDASVPPVPAAPAKLILNDAAEQYYRSSVTSTSAIVEQVVEVNDKEMDEDDMPTARPIVPANGSSSSVTLAEPTSPEVEDAPTEIVTVYDPEYARKQQEVALSNLDRTEIWLMAQRAYLKPLEASQTEEHDRNLGTILEAADEEVESFLEQEIPSAPRKKTVRFSEIITKTDIPRRLPSKLSRQESAYYRAFQDYVIRSSKQDVFVHQLPRFEALQAQRVCLREFHRNQLLGKYQLSVVPQSAKKRLSANVARGDDILVDDPEKLRREKECEAMSQMAMPAWHVAAIKMLNGGKLISAPVAKRLGRLSRMAPGRDGVARDRARILDLGGQSACDWAWHCALQYPNTKIYTVTTKAIRQLSNSNVRGPPNHRQVAVERLTRLPFKDNQFDLISARELHSILKFIGENGEDEWETCLRECLRVLKPGGYLEFSLLDSDIMNAGPLGLAKSVEFGFDLKTLGYDPNPTKMFLGRLSRAGFDEVRRAWVCLPMGARPPSQQQEKPLPSLPAVRANPTGEEVRTVTMEAMVTGSTDGVANVTGIVGGWSWERWLLRCEMEKVSGELRLADTVTAGPAMREAGKSVEGVAAIVEEGRGCGAGWRMLNGYARKPKTGTGLISVGFEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDX3</accession>
    <name>E3QDX3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_04205</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093081.1">
        <property type="nucleotide sequence ID" value="XM_008094890.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDX3"/>
    <dbReference type="GeneID" id="24409570"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04205"/>
    <dbReference type="HOGENOM" id="CLU_2072957_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ29061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="118" mass="13763" checksum="F75574FA1730150B" modified="2011-01-11" version="1">MALDNTLIRAASQKQFLDHCLSTIHDLTSQTPLPSLSTRYNCIRQPEPNGGGRRSSVYYETHYEIHYEIHDEIHYEIHYETHYEIHYEIHYEIHYETFPAGAASAISDWSAVLPLLVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QE26</accession>
    <name>E3QE26_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Haloacid dehalogenase-like hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_04258</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093134.1">
        <property type="nucleotide sequence ID" value="XM_008094943.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QE26"/>
    <dbReference type="STRING" id="645133.E3QE26"/>
    <dbReference type="GeneID" id="24409623"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04258"/>
    <dbReference type="eggNOG" id="ENOG502QR7R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_11_1_1"/>
    <dbReference type="OrthoDB" id="426235at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033883">
        <property type="term" value="F:pyridoxal phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd01427">
        <property type="entry name" value="HAD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43885">
        <property type="entry name" value="HALOACID DEHALOGENASE-LIKE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43885:SF1">
        <property type="entry name" value="SUPERFAMILY HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G13290)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ29114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="253" mass="27587" checksum="20361A5441DBCE15" modified="2011-01-11" version="1">MAAVTRRQFAPLKPGAAANSNAPRLKGIVFDMDGTLCEPQTYMFGEMRQALGITKSVDILDHIYALPTQEAQETAMDSIRQIERNAMASQVAQPGLADLMSYLDRRSVRKGICTRNFDGPVAHLLGKFLEGSLFEPIITRDFRPPKPDPAGILHIARSWGLVKPAESQSGPRDEATQGSQVMQGDASELIMVGDSIDDMTAGRRAGAATVLLANDVNAHLIDHEHTDLVIRRLDELIPILEEGFSGRELTPST</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEH3</accession>
    <name>E3QEH3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">E3 ubiquitin-protein ligase</fullName>
            <ecNumber evidence="10">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_04423</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 10">Belongs to the E3 ubiquitin-protein ligase UBR1-like family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="10"/>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093299.1">
        <property type="nucleotide sequence ID" value="XM_008095108.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QEH3"/>
    <dbReference type="GeneID" id="24409788"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04423"/>
    <dbReference type="eggNOG" id="KOG1140">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000684_1_0_1"/>
    <dbReference type="OrthoDB" id="26387at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000151">
        <property type="term" value="C:ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071596">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process via the N-end rule pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16482">
        <property type="entry name" value="RING-H2_UBR1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19673">
        <property type="entry name" value="UBR-box_UBR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.110.30:FF:000001">
        <property type="entry name" value="E3 ubiquitin-protein ligase UBR2 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003769">
        <property type="entry name" value="ClpS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044046">
        <property type="entry name" value="E3_ligase_UBR-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_bL12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039164">
        <property type="entry name" value="UBR1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055194">
        <property type="entry name" value="UBR1-like_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003126">
        <property type="entry name" value="Znf_UBR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21497:SF24">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE UBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21497">
        <property type="entry name" value="UBIQUITIN LIGASE E3 ALPHA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02617">
        <property type="entry name" value="ClpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18995">
        <property type="entry name" value="PRT6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22960">
        <property type="entry name" value="WHD_UBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02207">
        <property type="entry name" value="zf-UBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00396">
        <property type="entry name" value="ZnF_UBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="ClpS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51157">
        <property type="entry name" value="ZF_UBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7 10" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UBR-type" evidence="12">
        <location>
            <begin position="84"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="UBR-type" evidence="9">
        <location>
            <begin position="84"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="399"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="466"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1283"/>
            <end position="1306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1322"/>
            <end position="1345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="422"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1329"/>
            <end position="1339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ29279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="2138" mass="241904" checksum="0E5FD287EAF66E67" modified="2011-01-11" version="1">MEPTMSTQERQLCEFLRELPARWNYEYDDQAHHDLLDSLFWSLAGGERYMPLFFPSGRPSHNHKLHDAQGAVEGAEYTEAARGKRCGHIFKPGEASYSCRTCSTDDTCVLCMRCFDSTDHAGHMVRISISVGNSGCCDCGDDEAWRLPMFCTIHSETDPEKGEGKGKEPAGLPEDLVQNMQMTIGRVFDYICDVISCSPEQLRQGKTADSIQADEELSRLSPDIYGEGPSGHPEYALVLWNDEKHTMEDVQNQIARACRTTEAQALQRATETDLIGRSILKRLDDLDALLEMATKLEHIKVTVTIRSSRDTFREQMCGAMIEWLSDIAGCSVGTDHTILRNTVCQEMMKPWRKGSPGSHAIVGKDGIYDEEKFLRNLEHSQSFTQHVLLQVQRIATQQQARAADSDDEDIDMGRGNGTPDSDAGDDDDDDEIDDDDIMMVDVRADGPGDIGLEWRGNDQALEEDEATMAGYPPPPPPPAAARRATRDRDLTPSDSDTAEPLIAPAIYAKANLEIPKTPGQGEKAPSPKPGRYWLETPPGYMNRENVPPAEDVFQRVRLDWLILFDLRMWKKVRNDLRSLYISTVVSIPEFKRILGLRFAGLYTTLAQLYLIGDREPDHSIINLSLQMLTTPSITAEIVERGNFMTSLLAIFYTFLTTRQVGYPWDVSSNAVLAFDSGSVTNRRMYHFYLDLKYLFGSPQVQEKLRTEERYLLQFLDLVKLHQGIGPNVRAVGEHVEYETDSWITASLVTREINRLARQLADAYRNVPDNEAHFVAQAIRLTAKAVILHSVGAERHRFKQAEIKEEIKFKTLGDFEFDNESARYDVVKFTVEEDPISFHHALHYTLSWLIECGKSLPASSMKALLSFTTQDLKLPPRSMGRKVMPRRDNSPEDNLMAAFDYPLRVCAWLAQIKANMWVRNGISLRHQAATYRGVSQRDVSHHRDIFLLQTAMVIADPSRVLASIIDRFGMEKWVKGIFEQKSTAQDDAQHLDVVEDMIHLLIVLLSDRTSLIASEDEPNANVLAIRRDLTHILCFKPLSFNEISNKLPEKWQEQEDFHRVLDEMASFKPPEGVSDVGTFELRPEFVEHIDPYIAHYNKNQREESELAYRKKMAIKTGKPLEEIVYEPKLRPIPSGLFKDLAAFTNTGMFGQIIYYSLLYPLVAARLTPSVPTTRIETFLQVVLHLILIAISEDKADEGDMTEESLNSFVLIALTRTARSNFMQEAPNAKTIVALLDMMSTKEEFKACHPKIGLILKRMRQKRPRNFENAYARLGVSVDRIDTASPANNSAEEERERKKKAALSRQAKVMAQFQQQQKSFLENQGNIDWGSDLEDDEEAEQTGDRKNNWKYPTGTCILCQEDTDDRRLYGTFALFNESHILRQTDLQDPDFVREAFHTPSSLDRSAEDIRPFGVAHENRQEVTKVNAKGEKFVSERQTIGKGFPSNLSRPGPVSTGCGHMMHYSCFEMYFDATNRRHHHQIARHHPENLRRQEFVCPLCKALGNAFLPIIWKGQEECFPGPLQSQRLFADFLDTQMRSGYYILGANRPPDEVQSSFASYTAGQVTGALAEKAPQLLEEAWTADESGSDSVVTNTPLTSLFPTASTPVTNRRSVQSDGSTLMGELARVYRRLRDTVRSNGFKTRHEKRSIELRERNELCHSDVLSKLVGYSVSAVEIQQRGTEAQYGMTLLEKIPEQSLTHLRILAETATAYRAVGGLKAGGDNWIEEEFRLDSERQHVQLFVSQYFGQETEHARRPVDAYSPLLSEDAFIFLTECVFGLIPAQNFDVTHILRLCYLAEIVKAVYHMGRNIPVSTWISHLLNRETQDPALKNFAEFCLAITKVGMEINVSHREMPADLGDNRGFGQPELDNLEGHYTFVKKYALTFLRKSVVLLYVKYGIDFNSHVSPQPDADELDRLTEALRIPTFDEMCASITDLGPTCGWPASTTSLVSGWVRHQIMWPGDDTDELPPSALLSHPGIFELVGLPKNYDALIEEATRRRCPTTGKDVSDPMICLLCGDVFCGQAVCCLKEETSPGDREPQRIGGSQQHMRKCQGNIGLFLNIRKCCIFYLFRLSGSFSSAPYIDKYGETDLGLRHGRQLFLNQKRYDSMLRNTFLSHGIPSFISRKLEAEINNGGWETI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEJ2</accession>
    <name>E3QEJ2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_04442</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093318.1">
        <property type="nucleotide sequence ID" value="XM_008095127.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEJ2"/>
    <dbReference type="GeneID" id="24409807"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04442"/>
    <dbReference type="HOGENOM" id="CLU_2263545_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="52"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ29298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="103" mass="11800" checksum="7743B953FBCAD8FF" modified="2011-01-11" version="1">MASVLTPPCTLVCLHGKPCIQQHTDRHGCIGASWPAVVVVVVVVGAVSVHGYKRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHHQYSTSFPARRLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEM2</accession>
    <name>E3QEM2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_04472</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093348.1">
        <property type="nucleotide sequence ID" value="XM_008095157.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEM2"/>
    <dbReference type="GeneID" id="24409837"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04472"/>
    <dbReference type="eggNOG" id="KOG1399">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006937_7_0_1"/>
    <dbReference type="OrthoDB" id="74360at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051209">
        <property type="entry name" value="FAD-bind_Monooxygenase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877:SF10">
        <property type="entry name" value="L-ORNITHINE N(5)-OXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ29328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="507" mass="57884" checksum="FB7FFA40A037051A" modified="2011-01-11" version="1">MARYVEAGKDGRVTYSQFACIGSGFAGIGMGAQLKRWYGIEDIQFFERHHTLGGTWFINKYPGCACDVPSALCSFSFEANPNWTRVLPTYSELWEYLNRVAHKYDLVRKMAFNVSVERCEWVEERARWRMTIRHLKSGAVYFHECQFLFVGTGALVTPNEIDVPGAENFKGVICHTGKWRPDIDLEGKRVVRFGNGCTAAQVVPSIVHKVKSLTQIIRSKHWIFPPIDRKVPDLIRLVVNRIPGMTALQRFAVFAMAEYAFLGFPLTRAGKMFRERQRRVNEGYMRATAPEKYHDLLIPDFEVGCKRRIFDAGYLQSLHADNMTLTNDKALEIVPEGVRTDKRLIEADVIIVAIGYHTNEFAAGIDIIGRRGETLQSHWESFGGPTAYLGSALNGFPNFVLLLGPNVVTGHTSAIMALENNINYSLRVLKPVLEGRATTAEPRREAEQDYTDEMQNALQKTVCNSGCRSWYFVKRKDGSLKKWNAMSYPYSQVYFWYRCLFPIYSHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFF7</accession>
    <name>E3QFF7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nascent polypeptide-associated complex subunit alpha</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Alpha-NAC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_04739</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NAC-alpha family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093615.1">
        <property type="nucleotide sequence ID" value="XM_008095424.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFF7"/>
    <dbReference type="STRING" id="645133.E3QFF7"/>
    <dbReference type="GeneID" id="24410104"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04739"/>
    <dbReference type="eggNOG" id="KOG2239">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057806_2_0_1"/>
    <dbReference type="OrthoDB" id="3169036at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005854">
        <property type="term" value="C:nascent polypeptide-associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22054">
        <property type="entry name" value="NAC_NACA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14358">
        <property type="entry name" value="UBA_NAC_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.70.30:FF:000002">
        <property type="entry name" value="Nascent polypeptide-associated complex (NAC), alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000006">
        <property type="entry name" value="Putative nascent polypeptide-associated complex subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.30">
        <property type="entry name" value="Nascent polypeptide-associated complex domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016641">
        <property type="entry name" value="EGD2/NACA0like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044034">
        <property type="entry name" value="NAC-like_UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038187">
        <property type="entry name" value="NAC_A/B_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002715">
        <property type="entry name" value="Nas_poly-pep-assoc_cplx_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21713">
        <property type="entry name" value="NASCENT POLYPEPTIDE ASSOCIATED COMPLEX ALPHA SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01849">
        <property type="entry name" value="NAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19026">
        <property type="entry name" value="UBA_HYPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015901">
        <property type="entry name" value="NAC_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01407">
        <property type="entry name" value="NAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51151">
        <property type="entry name" value="NAC_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NAC-A/B" evidence="8">
        <location>
            <begin position="49"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="121"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="21"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="127"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="151"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ29595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="203" mass="22246" checksum="F3E579FD81769E56" modified="2011-01-11" version="1">MANPRVEELPDDETKKVSVEEHEDESSDSEIEGEEAEGLPSGSTAIIHSRNEKKARKALEKLHLTRVQGITRVTLRRPKNILFVINNPEVYKSPNSNTYIVFGEAKIEDLNATAQQAAAQQLAAAGGEHDHAGHSHAEPSKAADAETKKDEEEDDGEEVDAEGIEDKDIELVMTQANVSRKKAIKALKENDNDIVNSIMALSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFS3</accession>
    <name>E3QFS3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BOD1/SHG1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_04902</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093778.1">
        <property type="nucleotide sequence ID" value="XM_008095587.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFS3"/>
    <dbReference type="STRING" id="645133.E3QFS3"/>
    <dbReference type="GeneID" id="24410267"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04902"/>
    <dbReference type="eggNOG" id="ENOG502S313">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012822_0_0_1"/>
    <dbReference type="OrthoDB" id="5579731at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055264">
        <property type="entry name" value="BOD1/SHG1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28034:SF1">
        <property type="entry name" value="NUCLEOMORPHIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28034">
        <property type="entry name" value="SET1 COMPLEX COMPONENT SHG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05205">
        <property type="entry name" value="COMPASS-Shg1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BOD1/SHG1" evidence="2">
        <location>
            <begin position="40"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="603"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="356"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="403"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="604"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="671"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="758"/>
            <end position="768"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ29758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="768" mass="88579" checksum="E6B9B3D46463EF38" modified="2011-01-11" version="1">MASASSTNPAMASTESPPAPKKYKASDLPLPSATRAAIESLAHSFKKKGGYDAIRKEVWDRFAASDYEAQVTKAILEVAEQEVERNPAQLLTLERGKAAALIDGALERSGVYQKAEQVITQLIDRAAIEERMRQLRRNDIGEEEAIAEQQRGAKTDEDYHAETMAKRAERERVREELRQKELAIEEEKRKIAREERKKIEKEREKAETQRKAERDARRAAREKLQAEREAEREERRRQRDKERSRDRDRDRSRSRSRRRDRDRDRDRERDRDERDRERREERDRKRKQRHEESEEAQQKLSKEQLERLEQEALADLLRESKRVTAKQPELEIDEALAPPPRKLAPASAITPFKKVSSRDSPKVPELKKAEAKTEARGATVTTTPKADAPAEKARSRSRSRATGKAERERDGDDDRRRRDDDDRRRRDRRVQEDASVVDPGLDLNDERELHLVHALDATAAGLTHVTTDVNEAAPSLATAEIAAEIVPALRGATEVARGLGRIVATGVGPVIAPTGEIAAARVSEEIGLAPVLGPVLIGEIVVSLHGSTAGTRSVATAAAPAHVGSGLLKGHEIVTAGADEKEATKMEEVRKREKEAKAYLAAQREAREKGMPVPGIDDKRSAGERSPEAKRKRDLDEIDRYVPPGRDRERPHDLARDDNERRRSRSRSRSHGKDRERDRDRDRDRDRDRDRDRRDRDRDRDRSRDRSRDRRDRDRDRDRDRDRDRDRDRDRDRDRDRDRDRRSRRDGSVSSRRDRRDRSRSRRRSRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFT1</accession>
    <name>E3QFT1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Tetratricopeptide</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_04910</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093786.1">
        <property type="nucleotide sequence ID" value="XM_008095595.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFT1"/>
    <dbReference type="STRING" id="645133.E3QFT1"/>
    <dbReference type="GeneID" id="24410275"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04910"/>
    <dbReference type="eggNOG" id="KOG1173">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011751_4_1_1"/>
    <dbReference type="OrthoDB" id="10006270at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005721">
        <property type="term" value="C:pericentric heterochromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032297">
        <property type="term" value="P:negative regulation of DNA-templated DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045842">
        <property type="term" value="P:positive regulation of mitotic metaphase/anaphase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558">
        <property type="entry name" value="CELL DIVISION CYCLE 16,23,27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558:SF9">
        <property type="entry name" value="CELL DIVISION CYCLE PROTEIN 16 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12895">
        <property type="entry name" value="ANAPC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 7" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="499"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ29766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="615" mass="69475" checksum="A025A20B41148194" modified="2011-01-11" version="1">MEKFLREWRQDALNKAQYDSAIFIGDKLLALTNDDKDAFWLAQVHFATGNYTRAQTFLAKQDLVARNVSCRYLAAHCLIKQSRFDEAVAVLGERNPTHLINNASNKRKANTAPLGRAVGHRGRMARDDAAEEEATNRKYEAAMCYLRGICYAKQNAFDRAKECYKDAVRIDVQCFEAFQQLMTNSLLSPDEEWAFLESLDFDAITVSGDVSSSQEAAEFTKMLYTTRLSKYREPSAFTAACDSLSTHYRLADNPDLLLAKADLLYTQCRYRDALAITESILENDKYNFSVHPLHLACLYQLKMKNALFLVSHDLADNHPEEPCSWLAVGIYYFAIDKIAEARRYFSKASMMDAHFGPAWIGFAHTFAAEGEHDQAISAYSTAARLFMGTHLPQVFLGMQNHALNNMTLAEEFLKTAYGLCKTDPLLLNEMGVVKYHQDKPQEAVQFFRAALKTAAEIDSDPQAWLSPRTNLAHAYRRLRLWKDAHVEFDEVLRQGGKDAAIFCAKALIYLEEGRPEKAIVPLHEALAINPQDGTATELLNKALEETSTIDFADGDELDAFEQELELSKAAAREQLSNKLPKLRRDVKGKAKVSRPRILVDEDEKGESMMEMTDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGN6</accession>
    <name>E3QGN6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PUM-HD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_05168</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit.</text>
    </comment>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ30024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094044.1">
        <property type="nucleotide sequence ID" value="XM_008095853.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGN6"/>
    <dbReference type="STRING" id="645133.E3QGN6"/>
    <dbReference type="GeneID" id="24410533"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05168"/>
    <dbReference type="eggNOG" id="KOG1488">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009803_0_0_1"/>
    <dbReference type="OrthoDB" id="668540at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003730">
        <property type="term" value="F:mRNA 3'-UTR binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010608">
        <property type="term" value="P:post-transcriptional regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07920">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033133">
        <property type="entry name" value="PUM-HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033712">
        <property type="entry name" value="Pumilio_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537:SF48">
        <property type="entry name" value="MEIOTIC COILED-COIL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537">
        <property type="entry name" value="RNA BINDING PROTEIN PUMILIO-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00806">
        <property type="entry name" value="PUF"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50302">
        <property type="entry name" value="PUM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50303">
        <property type="entry name" value="PUM_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PUM-HD" evidence="6">
        <location>
            <begin position="405"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="468"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="504"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="652"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="693"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="59"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="130"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="211"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="296"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="763"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="94"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="59"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="297"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="335"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="364"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="777"/>
            <end position="787"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ30024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="787" mass="86719" checksum="4D2527F3C83B1A6D" modified="2011-01-11" version="1">MSTPPSTGVIPQRSSPGFQETRLQENSKQSPEVAAKDVPAFKQKPTIVTLGTSKLVNQNALKVGSSTRNLPSRSQRRQKKTNQESATVAGTNPMDMLLAKLSEQQAALDQQNEALKSSDDKSLYTRGFDQSTATTNSVPITPATDTFPTTAPATRPASATLKENHGNMEEVLRLKLELARAQTKISRLDHELAQSRSIKQEDIPIPQTSARSGMFGAENPWSPNDDSSSDVGAPSVGGYGRSRPAWASHRGPPPFSNHVMPTPSSDSQSVGGDWYGGGRGGFNQGYMDPVGPYSMADGHRGDRTSYDTEVFSRPPSSRRNNRFDNSRWPSPQPYGGSNISGQNYAGFTPSPAPFEAMSGGPGSTTGNIGSGMYQSYNQQPIGSQLSPHATEFTTTDGWKTESIATEGQTYLPTTEPLNYRRLLDRNVNCNWKYIVDKIVCNNDQQASIFLQQKLKVGTPDQKYEIVEAIVAQAYPLMVNRFGNFLVQRCFEHGTPEQVVKIAEAIRGNTLNLSMDPFGCHVVQKAFDSVPEDYKSIMVQELLRRIPETVIHRYACHVWQKLFELRWSESPPQIMKFVNDALRGMWHEVALGETGSLVVQNIFENCLEEDKRPCIEEVLANIDIVAHGQFGNWCIQHICEHGAPADRSRAIDHVIRYAAEYSTDQYASKVVEKCLKIGGGEFLSRYLDRVCEGRLDRPRIPLVDIASDQYGNYLIQYILTHSGMQHREVVAAHIRKHMVSLRGSKFGSRVGMLCTNPAVATRPGPGVGPSMNRMGAGPRYGGPGGGYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGS9</accession>
    <name>E3QGS9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">SART-1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_05211</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNU66/SART1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ30067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094087.1">
        <property type="nucleotide sequence ID" value="XM_008095896.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGS9"/>
    <dbReference type="STRING" id="645133.E3QGS9"/>
    <dbReference type="GeneID" id="24410576"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05211"/>
    <dbReference type="eggNOG" id="KOG2217">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009379_2_0_1"/>
    <dbReference type="OrthoDB" id="5583at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000481">
        <property type="term" value="P:maturation of 5S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045347">
        <property type="entry name" value="HIND"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005011">
        <property type="entry name" value="SNU66/SART1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14152">
        <property type="entry name" value="SQUAMOUS CELL CARCINOMA ANTIGEN RECOGNISED BY CYTOTOXIC T LYMPHOCYTES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14152:SF5">
        <property type="entry name" value="U4_U6.U5 TRI-SNRNP-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19252">
        <property type="entry name" value="HIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03343">
        <property type="entry name" value="SART-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="288"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="398"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="486"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="582"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="178"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="57"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="288"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="433"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="587"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="600"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="621"/>
            <end position="635"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ30067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="643" mass="71747" checksum="ADFFE7395651C8CD" modified="2011-01-11" version="1">MDAATIEETNRIRVSLGMKPLPVPGAAPAAPQRDNSASDDEDAPSTLESRSAQAYDNYKKVRDAEVAKRNREERAAAAKREREAAQRHAILEGKSLGEAEDADGDAKAWLKAQKKRQKAIEKARKLEEEQAAAEAAALAAVEYTSKDLAGVKVAHELDNFLDGDEQILTLKDATIDQNEEEGDELENMDLKAKEQLQERMDIKKKKSAYDVFAAADGGTEQGILAQYDDEIYGKKGKKFTLDGSGAIAELGDILGAPEKSNKLQNIDLDVIQDAPTSDYLDISEIKVKKPKKKKSKSTRQKPVDEDDIFPLDTTPAGDDMMDLDSGAAVAKKRKVEDDTFVDDEDLQASLAIQRKNALKKRKRARPEDIARQLREQVDEPTEAQTGGVVIDEISEFVSNLNKPEQEERKPKRPKSVSVEPVTAMDVESDDEDHPMGDGSHEIPDDRAREASADIAATGVDEEKTISTGMGSTLALLRERGILKDAHGAELNMSERQKAEFLAEKRRIEREQEERARSQRERDRNSGRLDAMSTRDREERARQANAHRELQQSRVVDELFKKHYKPNVELKYVDDHGRTLDQKEAFKHMSHQFHGKGSGKGKTDKLLKKIEEEKRREAKPSFDTSENANMSSSSAKRQAGVRLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHJ4</accession>
    <name>E3QHJ4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF676 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05309</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697348">
        <property type="protein sequence ID" value="EFQ30165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094185.1">
        <property type="nucleotide sequence ID" value="XM_008095994.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHJ4"/>
    <dbReference type="STRING" id="645133.E3QHJ4"/>
    <dbReference type="GeneID" id="24410674"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05309"/>
    <dbReference type="eggNOG" id="ENOG502QQEZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020826_0_0_1"/>
    <dbReference type="OrthoDB" id="442243at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47842:SF2">
        <property type="entry name" value="DUF676 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47842">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="502"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="502"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="517"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="545"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="558"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="580"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="607" mass="65578" checksum="C390D99F7D0D04B5" modified="2011-01-11" version="1">MPRTLLLCFVHGFKGNDNTFHDFPDDLKRSVTKQLPDHRVESIIYPQYETKGELAQAAEAFLSWLKEQVMEVRKANVEKPWPPKDRQVGVVLVAHSMGGFVAADALFLAVNERATSNPSEDDPIFPLIQGILTFDTPYNGLARSMFVYGGFSNYQKPRTPGHPPGRHVGRRLFGPPRRQPGLEDVAADRRAPGTVGAIAAGGVAAYVNREAIISGLRSLNKGSVKEGYQQSIGALGQGLAYINRGTVGQSFAWLSDHFTFVGALLKQKELNRRLERMGALKGVGIHDFYASLGENGYWQGGYFVPERTFCAVPDEGHAASSIFSRQVLQEVDDEVQAHMSMFKPEKHKGYEKMTENAAEMVIQWFNSDAPLVDDAKFRDAPPEEAAEDHEVEETLEKAISNTTATEQEASEASGGDKADDEDASRPPSDGLPDESPIDIAAAASLVPLPADGEGDLVGDASAENMTTEEKRSYMQHLFQIAQSTGTGVKGWWPNKMPNMPSMPSIPNMPSMPKVPASVSSLGQVSMPSVSIWRKSTPSQTPTPAGDDDDKNDDTETDGGEKRDASAEGDKNEAGKGPEGAGNEVAKAAAATGALETADEAGDDKSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHT5</accession>
    <name>E3QHT5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05567</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697349">
        <property type="protein sequence ID" value="EFQ30423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094443.1">
        <property type="nucleotide sequence ID" value="XM_008096252.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHT5"/>
    <dbReference type="GeneID" id="24410932"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05567"/>
    <dbReference type="eggNOG" id="ENOG502SRHJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120129_0_0_1"/>
    <dbReference type="OrthoDB" id="5405107at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="156" mass="16758" checksum="14FEB792D247E95B" modified="2011-01-11" version="1">MAFPTNVLGVLIALASGFTLIYSVDSISRLKKYDDLEEKANKAAEWSLTAEKKLRDLQLTLATGLVCCLLSAVSGLAFSFSVAPGPGFVAVAWPVLLAAGLAYGRQFVRGFWASKIKVPKMKHFNEAISDMMMVQSMMKPLAGAWGLVAVCKLVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QI15</accession>
    <name>E3QI15_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">serine C-palmitoyltransferase</fullName>
            <ecNumber evidence="5">2.3.1.50</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_05647</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sphingolipid metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.50" evidence="5"/>
    <dbReference type="EMBL" id="GG697349">
        <property type="protein sequence ID" value="EFQ30503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094523.1">
        <property type="nucleotide sequence ID" value="XM_008096332.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QI15"/>
    <dbReference type="STRING" id="645133.E3QI15"/>
    <dbReference type="GeneID" id="24411012"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05647"/>
    <dbReference type="eggNOG" id="KOG1358">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015846_0_2_1"/>
    <dbReference type="OrthoDB" id="3168162at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004758">
        <property type="term" value="F:serine C-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046512">
        <property type="term" value="P:sphingosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000059">
        <property type="entry name" value="Serine palmitoyl CoA transferase subunit LcbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050087">
        <property type="entry name" value="AON_synthase_class-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693">
        <property type="entry name" value="CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693:SF2">
        <property type="entry name" value="SERINE PALMITOYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="12" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="6 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="11">
        <location>
            <begin position="124"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ30503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="515" mass="56814" checksum="EC8C666415803DD4" modified="2011-01-11" version="1">MDAGEAQTKVIAWLHEASEAFQKVPGSAVLIRYIQSSYQNDPIRSGIELVLFIFFVRYLLSPSYSTQKQNFIKLRDDEIDELVEDWSPEPLVSPQTALEEIEAERLPVIVGPTGPKTKLANGRTVTNLASYNFYNFNANEQIKDKAIQTLRTYGVGPCGPPQFYGTQDVHMKTEADIAAYLGTEACIVYAQAFSTISSVIPAFCKRGDIIVADRAVNYSIRKGMEASRSTIKWYAHGDMDDLERVIQKVVKDQKGKKLTRRFIVSEGLFETTGDSADLPRLVELKEKYRFRIILDETWSFGVLGRTGRGLTEAQNVDPSQVDMIAGSLAGPLCAGGGFCAGAKDVVEHQRLTAASYTFSAALPAMLAVTASETLSVLQSNPDILAQCRDNTKAMRAQLDPRSDWVVCTSSPENPIILLVLKAEVVAARKLTREDQERLLQDCVDEALANGVLITRLKSMPIANNLDPKDNSWQIQPALKVCITTGLPRKDIEKAGVTIRHAITKVMTRKSSSKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIV6</accession>
    <name>E3QIV6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RNA cytidine acetyltransferase</fullName>
            <ecNumber evidence="9">2.3.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">18S rRNA cytosine acetyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">NAT10</name>
        <name evidence="15" type="ORF">GLRG_05938</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA-binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a cytidine in 18S rRNA + acetyl-CoA + ATP + H2O = an N(4)-acetylcytidine in 18S rRNA + ADP + phosphate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:51424"/>
            <dbReference type="Rhea" id="RHEA-COMP:13575"/>
            <dbReference type="Rhea" id="RHEA-COMP:13576"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:74900"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a cytidine in tRNA + acetyl-CoA + ATP + H2O = an N(4)-acetylcytidine in tRNA + ADP + phosphate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53876"/>
            <dbReference type="Rhea" id="RHEA-COMP:13670"/>
            <dbReference type="Rhea" id="RHEA-COMP:13671"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:74900"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Interacts with TAN1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
            <location evidence="1 9">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the RNA cytidine acetyltransferase family. NAT10 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="9"/>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094814.1">
        <property type="nucleotide sequence ID" value="XM_008096623.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIV6"/>
    <dbReference type="STRING" id="645133.E3QIV6"/>
    <dbReference type="GeneID" id="24411303"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05938"/>
    <dbReference type="eggNOG" id="KOG2036">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004652_0_0_1"/>
    <dbReference type="OrthoDB" id="10067491at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990883">
        <property type="term" value="F:18S rRNA cytidine N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051392">
        <property type="term" value="F:tRNA cytidine N4-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016556">
        <property type="term" value="P:mRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904812">
        <property type="term" value="P:rRNA acetylation involved in maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051391">
        <property type="term" value="P:tRNA acetylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11040:FF:000002">
        <property type="entry name" value="RNA cytidine acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03211">
        <property type="entry name" value="RNA_acetyltr_Nat10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033688">
        <property type="entry name" value="NAT10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007807">
        <property type="entry name" value="TcmA/NAT10_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032672">
        <property type="entry name" value="TmcA/NAT10/Kre33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013562">
        <property type="entry name" value="TmcA/NAT10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027992">
        <property type="entry name" value="tRNA_bind_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10925">
        <property type="entry name" value="N-ACETYLTRANSFERASE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10925:SF5">
        <property type="entry name" value="RNA CYTIDINE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13718">
        <property type="entry name" value="GNAT_acetyltr_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05127">
        <property type="entry name" value="NAT10_TcmA_helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08351">
        <property type="entry name" value="TmcA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13725">
        <property type="entry name" value="tRNA_bind_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 9" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TmcA/NAT10 N-terminal" evidence="12">
        <location>
            <begin position="9"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="TcmA/NAT10 helicase" evidence="11">
        <location>
            <begin position="282"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="13">
        <location>
            <begin position="539"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="domain" description="Possible tRNA binding" evidence="14">
        <location>
            <begin position="775"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="434"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1018"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="447"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="287"/>
            <end position="296"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="479"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="638"/>
            <end position="640"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="645"/>
            <end position="651"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="740"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF13718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF13725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EFQ30794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1063" mass="118291" checksum="66EF718835EF9DD9" modified="2011-01-11" version="1">MSRKAVDQRIPNLIYNGLQEKKRSFFVVVGDHAKDVIVNLHYLMSQRDIKHNKSVLWAYKSKLLGFTSHRKKRENKIKKEIKRGTREANESDPFELFVSLHNIRYVYYKETEKVLGNTFGMCILQDFEAMTPNILARTIETVEGGGLVVLLLKGMTSLKQLYTMSMDIHARYRTEAHDDVVARFNERFILSLGSCDSCLVIDDEMNVLPISGGKNVKALPPADKDIAKTETQQELEDMKEALQDTQPVGSLVTIAKTVDQAKALLTFVDAIAEKTLRSTVTLTAARGRGKSAAMGVAIAAAVAHGYSNIFITSPSPENLKTLFEFVFKGFDALGYADHADYSIIQSTNPDFNKAIVRVNIHRAHRQTIQYIRPQDAHVLGQAELVVIDEAAAIPLPLVRKLMGPYLVFMASTINGYEGTGRSLSLKLIKQLREQSRPGAKTNSDTEVADRTTGKAAKDQGSSHQASRSLREITLSEPIRYAQGDSVEKWLNKLLCLDATLPKAKASSQGCPDPSQCELLKVNRDTLFSFHPIPEKFLQQMVALYVASHYKNSPDDLQLMSDAPAHELYVLIAPTSDGKLPEPLCVIQVALEGKISRQSVINSLSRGQRPSGDLIPWLVSQQYQDDEFASLSGARIVRIATNPEYVSMGYGTKALQLLTDFYEQKFTNLSENADLVMEETLPRVTDEELANTSLLTDDVHIRDIKKLPPLFARFSEIRPAALDYIGVSYGLTQQLHKFWKRAAFAPVYLRQTANDLTGEHTCVMLRPLENIADESWLGAFARDFQRRFQSLLSYQFREFQSVVALSIDESASSGAKLDGTEPTALTKEELDRFLTPFDLKRLESYANNMLDYHVILDLVPTLASLYFSGKLKADIKLTGVQQAILLAIGLQRKDMDVISQELSLPSSQLLAMFIKILRKITAHFGGLVNAAVEAELPKADAIGVSRENASGAHDDEVVDNRFAPLETSLEDELEEGGDEALAKLRKKQRELIDSLPLDQYEVEGDAPAWAEAEQAVKEGKAGVVSIKTSKSKRKAGPTAAEIYEEAFGDKKSHKKAKKSKKDRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIX6</accession>
    <name>E3QIX6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">alpha-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_05958</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing (1-&gt;4)-linked alpha-D-glucose residues with release of alpha-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.20"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.20" evidence="3"/>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094834.1">
        <property type="nucleotide sequence ID" value="XM_008096643.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIX6"/>
    <dbReference type="STRING" id="645133.E3QIX6"/>
    <dbReference type="GeneID" id="24411323"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05958"/>
    <dbReference type="eggNOG" id="KOG1065">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000631_11_0_1"/>
    <dbReference type="OrthoDB" id="5839090at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004558">
        <property type="term" value="F:alpha-1,4-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06602">
        <property type="entry name" value="GH31_MGAM_SI_GAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14752">
        <property type="entry name" value="GH31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000138">
        <property type="entry name" value="Putative alpha-glucosidase AgdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1760">
        <property type="entry name" value="glycosyl hydrolase (family 31)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030458">
        <property type="entry name" value="Glyco_hydro_31_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030459">
        <property type="entry name" value="Glyco_hydro_31_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762">
        <property type="entry name" value="ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762:SF133">
        <property type="entry name" value="P-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00129">
        <property type="entry name" value="GLYCOSYL_HYDROL_F31_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00707">
        <property type="entry name" value="GLYCOSYL_HYDROL_F31_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 8 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180486" description="alpha-glucosidase" evidence="9">
        <location>
            <begin position="26"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="10">
        <location>
            <begin position="342"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="11">
        <location>
            <begin position="780"/>
            <end position="873"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ30814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1004" mass="109452" checksum="D8E6C1F4398FDE48" modified="2011-01-11" version="1">MRYAMPARAPVLLSAVAIMALCTMARVEPPLAQQYLASITVGDSTAQFTVPASADEGAPLIPNVKDPEAVDPQSVCPGYTASNVQTTSHGFTAELDLAGPPCNLYGNDIEALSLVVEYLATDRLHVQVLPRYVGTENSTWFILPEELIQKPAADGKASSDGSDSDLQFKWANEPTFGFNVSRESTGDVLFTTAGTKLVFQDQFFEFASPLPKNYNLYGLGEVIHGFKLNNNLTRTIYASDAGDPIDGNIYGSHPVYLDTRYYQVDANSKEAVYVAEATDKNAEYKSYTHGVFLRNAHAQEILLRESNITWRGLGGTIDLYFYAGPTADAVMKSYHKTTVGLPAMQQYWTFGFHQCRWGYTSWDNLQEIVDDFAKFKIPLETIWADIDYMNQYRDFENDHNSWGYKDAASFLDSLHKNGQHFVPIVDSAIYAPNPKNASDAYATFDRGVDADAFMLNPDGSLYIGAVWPGYTVFPDWVGAVLNGSRTFEWWKSELVAWYQKVTFDGIWIDMSEVSSFCVGSCGSGNLTLNPAHPPFSLPGEPGNEVLQYPEGFGRTNSTEAAAVSSLSSSLAAATPSSSSTATSYYLRTTPTPGVRNVNYPPYVIDNIQGDLAVHAVSPNATHHGGAQEYDVHNLFGHQILNATYHALLSVFPGKRPFVIGRSTFAGSGKWAGHWGGDNASLWAYMFFSIPQALSFGIFGIPMFGVDTCGFDGNTDMELCSRWMQLSAFFPFYRNHNVIGAIPQEPYRWGAVADASRTAMAIRYALLPYMYTAFYRAHTLGDTVMKALAWEFTDEPWLAGADRQFLLGSAILVTPCLEQGASTVDGVFPGIGKGTVWYDWYNQSAIAGVSAGQNVTIDAPLGHIPVYIRGGYVIPTQEPGLTTKESRSNPWGLLVALDGKGAATGSLYVDDGESLEQEATLTVELSASEKSLKATPSGGYKDANPLGTVTVMGVQGGVSAVTLDGQDLDDANWSFDSDTRALRVTNLGPLTSEGAWSKPWGLAWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJ30</accession>
    <name>E3QJ30_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">DUF676 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_06012</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094888.1">
        <property type="nucleotide sequence ID" value="XM_008096697.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJ30"/>
    <dbReference type="GeneID" id="24411377"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06012"/>
    <dbReference type="eggNOG" id="ENOG502SJBC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002786_0_0_1"/>
    <dbReference type="OrthoDB" id="361039at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052374">
        <property type="entry name" value="SERAC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48182">
        <property type="entry name" value="PROTEIN SERAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48182:SF2">
        <property type="entry name" value="PROTEIN SERAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1079"/>
            <end position="1103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1115"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="15"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="443"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="478"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="528"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="668"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="807"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="935"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="445"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="539"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="809"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="830"/>
            <end position="842"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ30868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1221" mass="138851" checksum="DE9C1ACDFC72232A" modified="2011-01-11" version="1">MSEFKNWTQETEMAVLSEVAAAQNDSPERVEPRHSLPAQPSEKTHINSPESPRPSSPTPHWNRLPGFAHIDGDVNGRGYNETLVDIVCVPCPGADPVETWARDPLPEGYFGRPSDVSISAVKELAGASILSPTINRHLPMATHLWVRQGIRKEVSEARVLLYRHRELVEGMTLDDLALDLIEQVWNVRYGNQRSRPLFFIAHSVGGLVVKLALLHASRTERYKPFMYNCHGVSFFATPHRGSSYLSMKHLEDSIRRLLRLQRPLPRSISDYLRLGHKPLLKMHEEFSTIASELRIWTFYETIDSQLSGSGSTSRGRAKEVRFGAPLASIKSSMVGVRQEHVFSLDSEHSNCASFGVGNTETMNTYLQELAFAVQRAMELSSQYIHTPLNLKKHVKVEIIGFYEDPDAEMESAIRLYFTKLHLQKFLEQGPERCLEQRLQKTALRPHSDPDPPHPTQDPHKSNKGIGILSSFQELGQKVWQGHSDSPSRPKTPDSESQGSPGIMVTRPSAVEGSHSMPVETIRRMQSLKVPPLSPPGFNRPSSRSSNAGSTRSDPTDLELSPKAMYPESLPVMGVGKSYSEPFSRRQDRLSRGSALDDLTAGFSRPDPASRRFMWIHTPFTNPSWVKDILGVLANPHDPSFIKLSNNDNWASKHVIGRHSQSQAPFVKPSCNYIPPGSTPSPHPSPNLSGRTISGSGSSSGYLYMYLPFLHFDTYIDILHRRNFIKRRMQHGRARPVPSDVAELDSPELRMIWEYIGYDPPLNYRRTLDQFAYPSLRDTWARDDDQMLYKLTKDRTPNVMDRDQLMLQRGPTSGSTWSPGEKVSPSNTGLLEEDTLDTDDEETDLDETIKDGKVLMVDQLWLWAIDTTTLSTFFNRRESKRKEGPLFQQSDLRNSVYNELNGDLTGRCENALDLAAFITERMTSSLKRFRMQTFKDVSGSDSDSDGNRPESIKKRHKRELEEAERENRENTSALMELRDMEDELKSLVKLFEAQEVVVRNMKSIFEGEDTKHLTRHGLMYLEEALSKVDGYKSQTVEMLKRVDTTRTDYEKLLEMVQRKAQVDEVRWSRLQTELASSQNLSVMIFTTFTVIFLPLSFFSSLFGMNTVEWDRQLPTIGFIGAVSLPASAVIISAALVAAFSSRVQGFVRTGYKGGKNVLQALGSAVMEFMPRRKQEKRRVNKAEREERRTRKMDRGYDFWQNVRRERASEYRIPEVNRHRTRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJH8</accession>
    <name>E3QJH8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TMEM205-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_06160</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ31016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095036.1">
        <property type="nucleotide sequence ID" value="XM_008096845.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJH8"/>
    <dbReference type="GeneID" id="24411525"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06160"/>
    <dbReference type="eggNOG" id="KOG2886">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094297_2_1_1"/>
    <dbReference type="OrthoDB" id="1641132at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025423">
        <property type="entry name" value="TMEM205-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053009">
        <property type="entry name" value="Xanthocillin_Biosynth-Assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23241">
        <property type="entry name" value="LATE EMBRYOGENESIS ABUNDANT PLANTS LEA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23241:SF102">
        <property type="entry name" value="LD23009P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13664">
        <property type="entry name" value="DUF4149"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="TMEM205-like" evidence="6">
        <location>
            <begin position="20"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ31016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="178" mass="19887" checksum="62C627B307895719" modified="2011-01-11" version="1">MGIPLPAFMANIAFCHVIPYATLLGTSLFQTFVNTKSCHSELPRSAFTTLQKRLFPVYFRCQAVLLVLTAITFPPYGPSSLLLEKRDWAPLAIVGLTTVANLFIYGPKTRQAMIDRVHQETRDAKRPDAVDEPSPDMNAVKRLFSFSHAMSIHLNIIGIFGMVWYGGRLASKLNIETD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJR1</accession>
    <name>E3QJR1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Actin-related protein 2/3 complex subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_06243</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the Arp2/3 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasm</location>
            <location evidence="1 6">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ARPC3 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697353">
        <property type="protein sequence ID" value="EFQ31099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095119.1">
        <property type="nucleotide sequence ID" value="XM_008096928.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJR1"/>
    <dbReference type="STRING" id="645133.E3QJR1"/>
    <dbReference type="GeneID" id="24411608"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06243"/>
    <dbReference type="eggNOG" id="KOG3155">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094365_1_0_1"/>
    <dbReference type="OrthoDB" id="200404at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044396">
        <property type="term" value="P:actin cortical patch organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051654">
        <property type="term" value="P:establishment of mitochondrion localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007163">
        <property type="term" value="P:establishment or maintenance of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1760.10:FF:000002">
        <property type="entry name" value="Actin-related protein 2/3 complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1760.10">
        <property type="entry name" value="Actin-related protein 2/3 complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007204">
        <property type="entry name" value="ARPC3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036753">
        <property type="entry name" value="ARPC3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12391">
        <property type="entry name" value="ARP2/3 COMPLEX 21 KD SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04062">
        <property type="entry name" value="P21-Arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016315">
        <property type="entry name" value="ARP2/3_P21-Arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69060">
        <property type="entry name" value="Arp2/3 complex 21 kDa subunit ARPC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR016315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ31099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="193" mass="21920" checksum="6FBE0C5E409A2FCF" modified="2011-01-11" version="1">MPAYNSMFNADPNIPRLIGNFPLLPLRTKTRGPAYTLPFPNPPLPANESPDPDSESYDILDEVLALFRANTFFRNFEIQGPADRLLVYGIWFVSDCLTKIKPNAGVRDASKDVMNVALDTNFAIPGDPAWPLNQMYEPPRDRQDAEQLRQYLSQVRQELAARLLARVYDEGGDGKPSKWWLSFTKRKFMGKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJW9</accession>
    <name>E3QJW9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="15">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">GLRG_06301</name>
    </gene>
    <organism evidence="20">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits. Binds 90S pre-ribosomal particles and dissociates from pre-60S ribosomal particles after processing of 27SB pre-rRNA. Required for the normal formation of 18S rRNA through the processing of pre-rRNAs at sites A0, A1 and A2, and the normal formation of 25S and 5.8S rRNAs through the processing of pre-rRNAs at sites C1 and C2.</text>
    </comment>
    <comment type="function">
        <text evidence="15">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="13">Component of pre-60S ribosomal complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="15">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the DEAD box helicase family. DDX55/SPB4 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="15"/>
    <dbReference type="EMBL" id="GG697353">
        <property type="protein sequence ID" value="EFQ31157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095177.1">
        <property type="nucleotide sequence ID" value="XM_008096986.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJW9"/>
    <dbReference type="STRING" id="645133.E3QJW9"/>
    <dbReference type="GeneID" id="24411666"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06301"/>
    <dbReference type="eggNOG" id="KOG0345">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_26_4_1"/>
    <dbReference type="OrthoDB" id="7396459at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902626">
        <property type="term" value="P:assembly of large subunit precursor of preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000470">
        <property type="term" value="P:maturation of LSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd17960">
        <property type="entry name" value="DEADc_DDX55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056330">
        <property type="entry name" value="CTT_SPB4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025313">
        <property type="entry name" value="SPB4-like_CTE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13959">
        <property type="entry name" value="CTE_SPB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23681">
        <property type="entry name" value="CTT_SPB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01178">
        <property type="entry name" value="DUF4217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 14 19" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="8 15" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="17">
        <location>
            <begin position="46"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="18">
        <location>
            <begin position="284"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="541"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="613"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="541"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="567"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="584"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00038002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EFQ31157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="635" mass="71321" checksum="7DD18C15454EB879" modified="2011-01-11" version="1">MPPAPPEKKRDPRSWRGLTPPLAEWILDFVSSQGFQRMTPVQAACLPQFLGNKDVVVEAVTGSGKTLAFLLPIVQKLMRLDEPTKRGHVFSIIVSPTRELAIQIHAVLQSLVGFHPPSAEILPFLKEDEKRPDASVPVIVPQLLVGGTTTTQQDLSFFVRHAPNVLVSTPGRLVELLASPHVRCTQSSFELLVLDEADRLLDMGFKQDIQRILGYLPKQRRTGLFSASVSEAVSQIITVGLRNPVKIAVRVKSLRDGGIIEDRKTPVSLQMSYLVTPASQKLPALAKLLENLSPRPQRSIVFLSTCAAVDYFQHLLPTIMPSGFTIVPLHGKLPPKAREKSFSKFVNSVSPSVLICTDIAARGLDIPQVDFVCQIDPPSDPKVFIHRSGRAGRAGRKGLSVVFLQPGHEEDYIPFLEVRKTPIFPLTQPEMVVTEEEANAASEKFRDVLRSDRAFHDKAQRAFVSWVRSYNAHLTTSIFRTKDLDWADLGKAWGLLRLPRMPETKKWEGDKWLGNEDFDWDNFSYKDKTREAARLAAMEAERNGEKAAAADEVKRKRKTNEAWSKQTEQEGVRTERREKRRRKKEAERMSTMTEEEKIKAMELNEMIAEIRRKNQAQAAAAAGGKKDDEFDGFDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLF4</accession>
    <name>E3QLF4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_06667</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697357">
        <property type="protein sequence ID" value="EFQ31692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095712.1">
        <property type="nucleotide sequence ID" value="XM_008097521.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLF4"/>
    <dbReference type="GeneID" id="24412032"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06667"/>
    <dbReference type="HOGENOM" id="CLU_2867544_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="64" mass="7399" checksum="D36C8246CAA98DF8" modified="2011-01-11" version="1">MYIQSRGDGTLACLSDARQQQQQQQQQQQQQQQQQQYEYQQKHLIHGPSPSSPSAFLHLSVSKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLH3</accession>
    <name>E3QLH3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glycosyl hydrolase family 32</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_06686</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 32 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697357">
        <property type="protein sequence ID" value="EFQ31711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095731.1">
        <property type="nucleotide sequence ID" value="XM_008097540.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLH3"/>
    <dbReference type="STRING" id="645133.E3QLH3"/>
    <dbReference type="GeneID" id="24412051"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06686"/>
    <dbReference type="eggNOG" id="KOG0228">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001528_3_3_1"/>
    <dbReference type="OrthoDB" id="202537at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004575">
        <property type="term" value="F:sucrose alpha-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005987">
        <property type="term" value="P:sucrose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18622">
        <property type="entry name" value="GH32_Inu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.560">
        <property type="entry name" value="Exo-inulinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001362">
        <property type="entry name" value="Glyco_hydro_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018053">
        <property type="entry name" value="Glyco_hydro_32_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013189">
        <property type="entry name" value="Glyco_hydro_32_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013148">
        <property type="entry name" value="Glyco_hydro_32_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42800">
        <property type="entry name" value="EXOINULINASE INUD (AFU_ORTHOLOGUE AFUA_5G00480)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42800:SF2">
        <property type="entry name" value="INVERTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08244">
        <property type="entry name" value="Glyco_hydro_32C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00251">
        <property type="entry name" value="Glyco_hydro_32N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00640">
        <property type="entry name" value="Glyco_32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00609">
        <property type="entry name" value="GLYCOSYL_HYDROL_F32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 32 N-terminal" evidence="5">
        <location>
            <begin position="17"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 32 C-terminal" evidence="6">
        <location>
            <begin position="405"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ31711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="562" mass="61317" checksum="2EA8AE2C3421AD18" modified="2011-01-11" version="1">MARQAADRSGRWRPQIHFSPPSEWLNDPNGLFIDSEGVWHMYYQYADNVAGDGVKNWGHTSATNFYDWVDHPIAIPATARDGSIWSGSVVVDRNNSSGFFPSNKTSGNDNIIAYYTSWEPDQQSQHVAWSYDGGQTFNQYAGNPIISLNRHGFRDPKVSFHHETNTWVMVLSLENEVAFYTSKDLVKWDQSSIWNPQRNIGLIECPQFLQIPRKDKSGSVVGAKWVLTLSLGGGGPGGSAAVKYLTGEFDGTAFTPDAPSGRAAGRDIHARQDTFTLYDFDFGPDKYATAFFYSQKLNDAAEDAYSVTWAVDASQYGCCTPTASEGWRHCMGGVRRHWLDASTNRLMSAPAGDLSKLQTTKPGWNPIVEEKGVPGLEGSSAVIRDYNPAVEWTLTVRMAKSLLKEGSTASAQLVFKASQSTGNESVSLGLQFVGSSGSGVPSASVNIGRVSTAWDRTGTFAVSGVQVLDAASEEGADAKVEFTLHGILDRSLLEVYVNGGVEAGTMLYFTDKPLDSIALTRGSGPSDQGITFDFKAVALNSSWGTYEEKTVSQQDKWITEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLT0</accession>
    <name>E3QLT0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_06793</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697357">
        <property type="protein sequence ID" value="EFQ31818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095838.1">
        <property type="nucleotide sequence ID" value="XM_008097647.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLT0"/>
    <dbReference type="STRING" id="645133.E3QLT0"/>
    <dbReference type="GeneID" id="24412158"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06793"/>
    <dbReference type="eggNOG" id="ENOG502S1B6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019843_2_0_1"/>
    <dbReference type="OrthoDB" id="5210591at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="460"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="475"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="484" mass="53449" checksum="5B73D9D7345321C1" modified="2011-01-11" version="1">MCAPPSVNPIQAVISRLVPQATVQQVQVMPSVNCQRTYEVKVSNGTGLVLVVPPSSMVKLLRSERASVISEAAVLKWLAGKTIEQPLLQERTTEPNYLLEPPSHVAKEVKGTRSSIDDAAEDLRRMVPALVSHSAALNELGLEYSLLKPTRGVPIPELNPPLSPSERRKIDYQIGELYRQLCKQVSPTGRFGPAFAVLHSAASPSVTDLTKQAKRDVNARLMESRGVQSWTTAFHSMLEAVLRDGEDMQVMLGYGTIRRHFKRLEHILDEIKIPRLVAVDVGKDINTLALRKNRRGGIASFTPSKTKSALQTAPQTNGNDTENEGNAGQEIDSESNGAANVCLDCQDDITMTGMKDWSNFVFGDPLFALNFGRDPSSDFLAGFGGCSRRQDEISSIFSSDLIEDKENAHIRLLLYDCYHTITHIAKGYFRPQKDSHGRELEARRRLNAILAQLDVLEDTRIRRGRRPSGESGPAKRSRSGGKDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QME2</accession>
    <name>E3QME2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_07174</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096050.1">
        <property type="nucleotide sequence ID" value="XM_008097859.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QME2"/>
    <dbReference type="GeneID" id="24412539"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07174"/>
    <dbReference type="HOGENOM" id="CLU_2277293_0_0_1"/>
    <dbReference type="OrthoDB" id="3039123at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ32030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="102" mass="10919" checksum="6EF4C26AB3F6271E" modified="2011-01-11" version="1">MGEFTRFFRVSGINHCMTGPSAWFIGQGGGIDVAIAKTLPFDGEHNVFAAIVDWVEDGVPPETTTRTKLVNDTMALSIIFSGGIAGTHCRTCTRKTESQSPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QN80</accession>
    <name>E3QN80_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF952 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_07462</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697361">
        <property type="protein sequence ID" value="EFQ32318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096338.1">
        <property type="nucleotide sequence ID" value="XM_008098147.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QN80"/>
    <dbReference type="STRING" id="645133.E3QN80"/>
    <dbReference type="GeneID" id="24412827"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07462"/>
    <dbReference type="eggNOG" id="ENOG502SBXH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129452_2_0_1"/>
    <dbReference type="OrthoDB" id="3335358at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.170.20">
        <property type="entry name" value="Protein of unknown function DUF952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009297">
        <property type="entry name" value="DUF952"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34129">
        <property type="entry name" value="BLR1139 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34129:SF1">
        <property type="entry name" value="DUF952 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06108">
        <property type="entry name" value="DUF952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56399">
        <property type="entry name" value="ADP-ribosylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ32318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="125" mass="13761" checksum="F2F0F11AD9F7D0BF" modified="2011-01-11" version="1">MPAPTQMPQYLYKIVPEAPPSPLPAEYPLSDLDRNDGFIHLSTAEQVLGTADRFFSGATGLWLLKLPYAVLEAQIRWDELPAGAGCFPHLYGRNFGAADVADARGFTRPEGRAWSEVLRGDAWLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNC4</accession>
    <name>E3QNC4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_07506</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697361">
        <property type="protein sequence ID" value="EFQ32362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096382.1">
        <property type="nucleotide sequence ID" value="XM_008098191.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNC4"/>
    <dbReference type="GeneID" id="24412871"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07506"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_6_1"/>
    <dbReference type="OrthoDB" id="2250022at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000057">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF13">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="311"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="348"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="378"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="463"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="25"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ32362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="516" mass="57517" checksum="B45E49660D077418" modified="2011-01-11" version="1">MAPETGDGEANNVSKNAIEFSQVEDLAKSPSQEKIEQQHEITPKEIQGRFDLLRDLSDAEMEKLNKSVVRKIDFRMMPTITLMFLMRQRLTSYLDRINVSNARISGMQEDLHMSDTMWNLGISTFYIGYLIGQLPGNLWLAKANPRWFLPSTMVAWGAATICTPALKNGAGFAALRFVTGLAEAPFFPGITLMTSSWYNKHESPSRMAIWHAGNTVSNIISGFLAAGILTTMGGVAGLYSWQWFFLIEGIATFLVAFSAYALLPDWPHNTRFLTPPEREMAQYRILCSNGGVEEVDGGTWDGLSQAVKDPFTWIFCLMHFALVTAQSFKDFLPSIVKTFNFSQLMTYLIQAPPYAFAYAFACLVAWSSGRRQESFWHVVLPTVGSAIGCAVLISTANVGARYFALFLLISGTYSGLNLQLSWETTVVPAPRSKKAALIAIANCLSQVSHWFSPYFWPRAHEPFYRLGGGLILVGCLLVVVSASLARWRAIKLNKKLDEAEGYSEHSGVERGWRHAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNF9</accession>
    <name>E3QNF9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Carboxylesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_07716</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697362">
        <property type="protein sequence ID" value="EFQ32446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096466.1">
        <property type="nucleotide sequence ID" value="XM_008098275.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNF9"/>
    <dbReference type="STRING" id="645133.E3QNF9"/>
    <dbReference type="ESTHER" id="colgm-e3qnf9.a">
        <property type="family name" value="Fungal_carboxylesterase_lipase"/>
    </dbReference>
    <dbReference type="ESTHER" id="colgm-e3qnf9.b">
        <property type="family name" value="Fungal_carboxylesterase_lipase"/>
    </dbReference>
    <dbReference type="GeneID" id="24413081"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07716"/>
    <dbReference type="eggNOG" id="KOG1516">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_291340_0_0_1"/>
    <dbReference type="OrthoDB" id="3200163at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="3">
        <location>
            <begin position="14"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="3">
        <location>
            <begin position="571"/>
            <end position="991"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ32446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1048" mass="114621" checksum="CA42C98618DA3991" modified="2011-01-11" version="1">MASATRQLEHPVIGTVKGIVSNGVTQFLGVKYANLDHWFDNAQLVQYNGNGLNATRHGPQVISDPAGVNQEHLIIQKAIPVAEFPGLSSTECLNLNLTVPLEVKDSQPLPVLVFIHGGGFATGSNWWPQYDMKRLVQLASERGKPMIAAAISYRVGAPGFLTSEELQKEGFKSNQGHHDQRIALKWIKEYIAGFGGDPQQITVAGESAGGSSTTRLLYSNETLATQIIVLGGCPPLLAPLDAAVAEQVYHDVTKAFRLEDLSSSQRIKALSEVSPEDLLAKLEGVRPFLPILDGDTVPFTPTFETSRAKKVIPSGTSCRAMMIGYAPLDASIFGFVGLLHKKEGIATKFIQSISSSLSQHPDATTRILQAYEISEAAGDDESLIRVLQFASDLVFRASAELYAKSFHGNSYLLEFAERNPWDGPFKGHSTHVLDVAFLFQNYNEHLSEKQRQTAEAFAADVIDFVHGEAPWGRLRDAAGRMIYEHGTRTYKEDVAGSGKYDCVLTLGEEVGLDYLLKAWETFLFSQLQGLSGHREHNSEAYRCLQKIRMKADPVLASESLSSTLLGVGLERVVQFRGIPYGEIPSRFAEPRPKSALPREVNCTSFGPRCPQVAIDVGHLLRIPSQYKLPPEPEDEFKCLNLDVTTPRSCLSSKREQLPVLVWIHGGSQAVTFGSAASGVCDGTQVVEDSISQGKPIIVVTVQYRLNIFAFGDETSSKNLALKDQALALNWVQKHIAGFGGNPDNIFLAGESAGAVYCHAHLVAGAPIRGVILCSGSLYLSPPQSEEKAFILRQTLRKHLQGAGDFEIDTAPVDKLVEALESSGIQSWFLQTDSALADWQTKIGVAERLMIGDVQNEAVIWREGVWATDNAAVVDAFNLAGEDRDALKRVYNIYPDRPSSSKIGALDFINDYKFLLPAENVARLFKAAGKPAYRYLVDESNPWQPSNGAHHAVDLLFLFGGFDLSCFPSAKKTGEHMREAFIAFIHSQEPWNPSCYAGFGPYGSFQELDSAGVGCRRRMEAAEFLRSVPSPVLDKVFFALAAGRISLSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNJ5</accession>
    <name>E3QNJ5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07752</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697362">
        <property type="protein sequence ID" value="EFQ32482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096502.1">
        <property type="nucleotide sequence ID" value="XM_008098311.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNJ5"/>
    <dbReference type="STRING" id="645133.E3QNJ5"/>
    <dbReference type="GeneID" id="24413117"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07752"/>
    <dbReference type="eggNOG" id="KOG0192">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_31_0_1"/>
    <dbReference type="OrthoDB" id="1668230at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052751">
        <property type="entry name" value="Plant_MAPKKK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48011">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTIONAL COMPLEX SUBUNIT CAF120-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48011:SF4">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ32482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="267" mass="29702" checksum="C4DE2376F63996C1" modified="2011-01-11" version="1">MEQREIVEYHFYCPPGVQCILACGSSAFIGEVDDSTILKYPLEPGGDLTRLELEHKILTVVGRHPRIIGHKGFTETGLYLERAVNGTIFKDLTASDVPAPSLQQRLAWCRELSEAVEHVHSKRVILCDIQPANVLVDRCAHLKLAGFQGRYLSEDGNIILDGWSGEPCRYFCPRDDEFAANFKTDFFALGSTIYFIMTGQGVFPDIASGEAGWDDEVKSRFARGAFPHDSTACAIITQKCWMQQCNPAGEVLEDIRRAEQGLELALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNW7</accession>
    <name>E3QNW7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fasciclin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_07569</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697363">
        <property type="protein sequence ID" value="EFQ32555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096575.1">
        <property type="nucleotide sequence ID" value="XM_008098384.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNW7"/>
    <dbReference type="STRING" id="645133.E3QNW7"/>
    <dbReference type="GeneID" id="24412934"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07569"/>
    <dbReference type="eggNOG" id="KOG1437">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031281_2_3_1"/>
    <dbReference type="OrthoDB" id="286301at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050904">
        <property type="entry name" value="Adhesion/Biosynth-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900:SF77">
        <property type="entry name" value="FI19380P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900">
        <property type="entry name" value="PERIOSTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180626" evidence="1">
        <location>
            <begin position="23"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="2">
        <location>
            <begin position="24"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="2">
        <location>
            <begin position="177"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ32555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="394" mass="41340" checksum="5487DE7132C4111D" modified="2011-01-11" version="1">MISALLPAGLVGLLSLIDIVGAQQDDLGKVLQSQSNLTTYFNLIKKYPEVILKLPSYDGVTVVAPSNAAFENIPGTQLNGKWNESDPSIAIPILEYHILQGTVSTGALETGPSVLHSSLLQNPAWTNVTGGQNVMVNKQPGDVIVFTSSKGTRTTQVKGDIRFAGGLIQVVDNLLIPPARLENSTESFGLSSFLGALYTAKLLPSLSEKRNVTIFAPRNEAFQRVAGHLEDLDENAFRNLLNYHVVEGQVVPSLGLKNGTSLYTLTGQSLRVIRSGNNLFLNSAQVVQPDILLANGIMHIIDNVLNPDKATAVPNPTAISQEPVYPESSASGLPFTSAIPCTVSCPVTSTTITTAAASTRTSTTAIMTTTSPGVAARTVAAAGAALLAGLAALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3QP54</accession>
    <name>E3QP54_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Catabolic 3-dehydroquinase</fullName>
            <shortName evidence="3">cDHQase</shortName>
            <ecNumber evidence="3">4.2.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">3-dehydroquinate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">qutE</name>
        <name evidence="7" type="ORF">GLRG_07656</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Is involved in the catabolism of quinate. Allows the utilization of quinate as carbon source via the beta-ketoadipate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>3-dehydroquinate = 3-dehydroshikimate + H2O</text>
            <dbReference type="Rhea" id="RHEA:21096"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16630"/>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
            <dbReference type="EC" id="4.2.1.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Aromatic compound metabolism; 3,4-dihydroxybenzoate biosynthesis; 3,4-dihydroxybenzoate from 3-dehydroquinate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homododecamer. Adopts a ring-like structure, composed of an arrangement of two hexameric rings stacked on top of one another.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the type-II 3-dehydroquinase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.10" evidence="3"/>
    <dbReference type="EMBL" id="GG697363">
        <property type="protein sequence ID" value="EFQ32642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096662.1">
        <property type="nucleotide sequence ID" value="XM_008098471.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QP54"/>
    <dbReference type="STRING" id="645133.E3QP54"/>
    <dbReference type="GeneID" id="24413021"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07656"/>
    <dbReference type="eggNOG" id="ENOG502S1A9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090968_1_0_1"/>
    <dbReference type="OrthoDB" id="8191625at2759"/>
    <dbReference type="UniPathway" id="UPA00088">
        <property type="reaction ID" value="UER00178"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003855">
        <property type="term" value="F:3-dehydroquinate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046279">
        <property type="term" value="P:3,4-dihydroxybenzoate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019631">
        <property type="term" value="P:quinate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00466">
        <property type="entry name" value="DHQase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.9100">
        <property type="entry name" value="Dehydroquinase, class II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00169">
        <property type="entry name" value="AroQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001874">
        <property type="entry name" value="DHquinase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018509">
        <property type="entry name" value="DHquinase_II_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036441">
        <property type="entry name" value="DHquinase_II_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01088">
        <property type="entry name" value="aroQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003804">
        <property type="entry name" value="PRK05395.1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003805">
        <property type="entry name" value="PRK05395.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003806">
        <property type="entry name" value="PRK05395.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003807">
        <property type="entry name" value="PRK05395.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21272">
        <property type="entry name" value="CATABOLIC 3-DEHYDROQUINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21272:SF3">
        <property type="entry name" value="CATABOLIC 3-DEHYDROQUINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01220">
        <property type="entry name" value="DHquinase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001399">
        <property type="entry name" value="DHquinase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52304">
        <property type="entry name" value="Type II 3-dehydroquinate dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01029">
        <property type="entry name" value="DEHYDROQUINASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="1 3" id="KW-0672">Quinate metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="3 4">
        <location>
            <position position="24"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3 4">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <begin position="102"/>
            <end position="103"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="3 6">
        <location>
            <position position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001399-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001399-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001399-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ32642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="148" mass="16053" checksum="1E88F02CF13C321F" modified="2011-01-11" version="1">MAKSILLINGPNLNLLGTREPHIYGSTTLEQLEASSKEHAKSLGADLQSFQSNTEGAIVDRIHAARGNVDVIIINPAAYTHTSVAIRDALLGVDIPFIELHISNTHSRESFRHRSYLSDKAVAVIMGFGIHGYGYAIDHAAKNIKPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPI4</accession>
    <name>E3QPI4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Parasitic phase-specific protein PSP-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_07916</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697364">
        <property type="protein sequence ID" value="EFQ32772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096792.1">
        <property type="nucleotide sequence ID" value="XM_008098601.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPI4"/>
    <dbReference type="STRING" id="645133.E3QPI4"/>
    <dbReference type="GeneID" id="24413281"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07916"/>
    <dbReference type="eggNOG" id="ENOG502SM17">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033465_6_1_1"/>
    <dbReference type="OrthoDB" id="4521223at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF9">
        <property type="entry name" value="SPHINGOID LONG-CHAIN BASE TRANSPORTER RSB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="250"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="280"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="280"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="302"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ32772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="312" mass="34610" checksum="1435EAF1A87B2B0F" modified="2011-01-11" version="1">MATLPDGLVAFGPEANCTLELCPLEWSILRYQPSIPASGVFIAFFALALIVHAVQGIRWKTWGFTASMVCGCVLEIVGYVGRLIIHDNPFDFNGFLIQIICITVAPVFFSAAIYVLLSQTINFLDRSISRFSPRLFYWIFIPLDIVSLILQALGGALSSVSTTRAAVDQGVNISLVGLVLQVAALLAFCGLFADYMITYSRSRTRPPMSQRLKLYLLFLSLSTLFILLRCVYRVVELHEGYFSHWFRDQALFIALESAVMVLAVFSLSIGHPGLLFTRREGKRRSTDDPHSLTSGGESVHAANEKKSGTERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPP8</accession>
    <name>E3QPP8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_07969</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697365">
        <property type="protein sequence ID" value="EFQ32825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096845.1">
        <property type="nucleotide sequence ID" value="XM_008098654.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPP8"/>
    <dbReference type="GeneID" id="24413334"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07969"/>
    <dbReference type="eggNOG" id="ENOG502RQTI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_688041_0_0_1"/>
    <dbReference type="OrthoDB" id="4849301at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="189"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="393"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="28"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="66"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="109"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="398"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ32825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="422" mass="46782" checksum="F705B69AB992F9BE" modified="2011-01-11" version="1">MPSNNTKRSAVRCHPMSTRSTAAWRETSSSSDSDSSENSVPDSSPNTSPARVSDMPNPSRKRRRGASGSEEPEASSSVTRPMKKLKVSGGRASSPVDSEDAEGSLPVRRPMKKLRISKRHSPPTDIDSDDDADETVSPSEPADELDGGDSAPNTPSPALHVRSDGFWPTIRNDYLRSLEDESIRVDIPCVICGDDCLVDGHLRWQLRRPEGVGREVPAILCCGHMIGDECLEKWRRTRREEGEPPSCPICRMPLQCSDCGVAMPGWPLTRDIPVGGTRTLQQGGHRVTRCNACEAEVILGDGMRLSYYAEGARPDESLLLKAWFDAVRNRVAAEVRAGRHGHVASVDVTDLVLSETFEAMMRRLDDFEEGVHGRVEETLDLMERDLDLRLPWNHPVPSEDEEEEEGDNDYDLWPGTVFRWSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPR6</accession>
    <name>E3QPR6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">arginine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Arginyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_07987</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>tRNA(Arg) + L-arginine + ATP = L-arginyl-tRNA(Arg) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:20301"/>
            <dbReference type="Rhea" id="RHEA-COMP:9658"/>
            <dbReference type="Rhea" id="RHEA-COMP:9673"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78513"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.19"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.19" evidence="2"/>
    <dbReference type="EMBL" id="GG697365">
        <property type="protein sequence ID" value="EFQ32843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096863.1">
        <property type="nucleotide sequence ID" value="XM_008098672.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPR6"/>
    <dbReference type="STRING" id="645133.E3QPR6"/>
    <dbReference type="GeneID" id="24413352"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07987"/>
    <dbReference type="eggNOG" id="KOG1195">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006406_6_2_1"/>
    <dbReference type="OrthoDB" id="68056at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004814">
        <property type="term" value="F:arginine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006420">
        <property type="term" value="P:arginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07956">
        <property type="entry name" value="Anticodon_Ia_Arg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00671">
        <property type="entry name" value="ArgRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.70:FF:000006">
        <property type="entry name" value="Arginyl-tRNA synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.730.10:FF:000006">
        <property type="entry name" value="Arginyl-tRNA synthetase 2, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000058">
        <property type="entry name" value="Mitochondrial arginyl-tRNA synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.70">
        <property type="entry name" value="Arginyl tRNA synthetase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001278">
        <property type="entry name" value="Arg-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005148">
        <property type="entry name" value="Arg-tRNA-synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036695">
        <property type="entry name" value="Arg-tRNA-synth_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035684">
        <property type="entry name" value="ArgRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008909">
        <property type="entry name" value="DALR_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00456">
        <property type="entry name" value="argS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11956:SF11">
        <property type="entry name" value="ARGININE--TRNA LIGASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11956">
        <property type="entry name" value="ARGINYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05746">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00750">
        <property type="entry name" value="tRNA-synt_1d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01038">
        <property type="entry name" value="TRNASYNTHARG"/>
    </dbReference>
    <dbReference type="SMART" id="SM01016">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00836">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55190">
        <property type="entry name" value="Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 13" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arginyl tRNA synthetase N-terminal" evidence="12">
        <location>
            <begin position="31"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="DALR anticodon binding" evidence="11">
        <location>
            <begin position="517"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ32843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="633" mass="71343" checksum="A2398DCEEC78ABFB" modified="2011-01-11" version="1">MADQLTVQLEKLSIGKLESFPGCYPDVNPIDIYRSHITSLLHDVTGVEKTIIYNALQWTQSLDKGDMVLAVPALRIKGKKPAELTAEWLEKFPESPLIEKPISLQNGSFLQFWFKAGPLSQLLIPQVRNRGQAFGKNPNNGLKNPEDPSQGKKKIIVEFSSPNIAKPFHAGHLRSTIIGGFIANLYDGAGWDVTRINYLGDWGKQYGLLALGFERFGSEDALKADPINHLYEVYVKINAAMSDEKEQIAAKEQAGEDVAALKDNSLDEQARKYFKAMVAGDEAAVAQWRRFRDLSITRYKETYARLNIHFDEYSGESQVSEQDMEAAAKKLQDMNISEESEGAVIIDFSKHIPGKAGKSLERPIIRKKDGTALYLTRDISELLHREKKYNFDHMIYVVASQQDLHLKQLFKIIELMGYPETAKKCQHINFGMVLGMSTRKGTVKFLDDILRDVGDKMHEVMKKNETKYSQVENPEATADILGISSVMVQDMSGKRINNYKFDMDTMTSFEGDTGPYLQYAHARLCSIFRKAGVPEEEVVKADLSLLTEKHAIELIRVVSQYPDVVQNTLKTLEPTTVLTYLFRLTHVVSSSYDVLRIVGSEPEIQKARLALYSSARTVLYNGMRLLGLSPVER</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQA4</accession>
    <name>E3QQA4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Amine oxidase</fullName>
            <ecNumber evidence="9">1.4.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_08186</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7 9">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the flavin monoamine oxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.-" evidence="9"/>
    <dbReference type="EMBL" id="GG697367">
        <property type="protein sequence ID" value="EFQ33042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097062.1">
        <property type="nucleotide sequence ID" value="XM_008098871.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQA4"/>
    <dbReference type="STRING" id="645133.E3QQA4"/>
    <dbReference type="GeneID" id="24413551"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08186"/>
    <dbReference type="eggNOG" id="KOG1238">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002865_6_0_1"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001613">
        <property type="entry name" value="Flavin_amine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF201">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00757">
        <property type="entry name" value="AMINEOXDASEF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0274">FAD</keyword>
    <keyword evidence="3 8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180688" description="Amine oxidase" evidence="10">
        <location>
            <begin position="18"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="11">
        <location>
            <begin position="105"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="506"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="549"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="37"/>
            <end position="38"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ33042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="568" mass="61269" checksum="E118BE8E2D147B1D" modified="2011-01-11" version="1">MRGFLTISTLLSGAASAAVRFTNSTDSHDYVIVGGGTSGLALANRLSENPAVSVLVIEAGGSVFDNVNVTNPNGYGLAFGTDIDFAFQTTNQTYGGGQVLTMRAAKALGGTSTINGLAYTRAESSQVDAWEKLGNEGWNWNALFPYYLKSEHFQTPEPARQVAGHLEYESKDHGENGPLLTGWTFGQTNGTIPAVLNSTYKNLGLPWNEDVNGGNMVGFSVFPRTVDQENAVREDAARAYYYPYQNRTNLQVLLNTSAQKLTWKNATVPTADGVEVVSADGSSRIVKARKDVILSAGSLHGIETVVNLPTVGENLQDQMNNGLSFAMKNITVDGAITTVAYPSAEQMFDNVDEIAAQVKESLPAYAATVASVNGNVTQAADLLEFFEMQWSLIFESKIPIAEVLVNAAQGTWSSEYWGLLPFSRGSIHISETSTANAIINPNYFLLDWDLLHQVQTAKFIRKLYGTAPFSTYAGTETRPGVDVVAEDADIEGWTGYIKGNYRSNFHPVGTAAMMPREKGGVVDANLKVYGTTNVRVVDASVLPFQVCGHLVSTLYAVAERAADLILEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQH4</accession>
    <name>E3QQH4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08256</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697367">
        <property type="protein sequence ID" value="EFQ33112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097132.1">
        <property type="nucleotide sequence ID" value="XM_008098941.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQH4"/>
    <dbReference type="GeneID" id="24413621"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08256"/>
    <dbReference type="HOGENOM" id="CLU_2960629_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ33112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="59" mass="6577" checksum="F77C4305551CAE84" modified="2011-01-11" version="1">MNDSAEYVPEAYAAPATGYDDGDPTRFKGQLPYPQVPQDLQCAEGNMKRRWLCPLVNTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQX4</accession>
    <name>E3QQX4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Poly(A) polymerase</fullName>
            <ecNumber evidence="11">2.7.7.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">GLRG_08406</name>
    </gene>
    <organism evidence="19">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Polymerase that creates the 3'-poly(A) tail of mRNA's.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>RNA(n) + ATP = RNA(n)-3'-adenine ribonucleotide + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:11332"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17347"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="ChEBI" id="CHEBI:173115"/>
            <dbReference type="EC" id="2.7.7.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="13">Binds 2 magnesium ions. Also active with manganese.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the poly(A) polymerase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.19" evidence="11"/>
    <dbReference type="EMBL" id="GG697369">
        <property type="protein sequence ID" value="EFQ33262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097282.1">
        <property type="nucleotide sequence ID" value="XM_008099091.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQX4"/>
    <dbReference type="STRING" id="645133.E3QQX4"/>
    <dbReference type="GeneID" id="24413771"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08406"/>
    <dbReference type="eggNOG" id="KOG2245">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011511_4_1_1"/>
    <dbReference type="OrthoDB" id="412748at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071920">
        <property type="term" value="C:cleavage body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033620">
        <property type="term" value="C:Mei2 nuclear dot complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990251">
        <property type="term" value="C:nuclear exosome focus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990817">
        <property type="term" value="F:poly(A) RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0180010">
        <property type="term" value="P:co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033621">
        <property type="term" value="P:nuclear mRNA surveillance of meiosis-specific transcripts"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd05402">
        <property type="entry name" value="NT_PAP_TUTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.460.10:FF:000002">
        <property type="entry name" value="Poly(A) polymerase alpha, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1410.10:FF:000001">
        <property type="entry name" value="Putative poly(A) polymerase gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.590">
        <property type="entry name" value="Poly(A) polymerase predicted RNA binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011068">
        <property type="entry name" value="NuclTrfase_I-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007012">
        <property type="entry name" value="PolA_pol_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048840">
        <property type="entry name" value="PolA_pol_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007010">
        <property type="entry name" value="PolA_pol_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014492">
        <property type="entry name" value="PolyA_polymerase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10682">
        <property type="entry name" value="POLY A POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10682:SF10">
        <property type="entry name" value="POLYNUCLEOTIDE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04928">
        <property type="entry name" value="PAP_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20750">
        <property type="entry name" value="PAP_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04926">
        <property type="entry name" value="PAP_RNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018425">
        <property type="entry name" value="PolyA_polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55003">
        <property type="entry name" value="PAP/Archaeal CCA-adding enzyme, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 11" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7 11 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Poly(A) polymerase nucleotidyltransferase" evidence="17">
        <location>
            <begin position="9"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="Poly(A) polymerase central" evidence="16">
        <location>
            <begin position="216"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="Poly(A) polymerase RNA-binding" evidence="15">
        <location>
            <begin position="363"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="444"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="581"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="444"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="613"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="106"/>
            <end position="108"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="243"/>
            <end position="244"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR018425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR018425-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR018425-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF20750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EFQ33262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="631" mass="70655" checksum="323899C18E124C99" modified="2011-01-11" version="1">MTGEERPLGVTPPISLALPTEAENHAMQTLIDELRRQNTFESPTDTEKRQALSETVLEHLARICDEFVKRVARKREEGNDALIRDARGKIFTYGSYRLGVYGPGSDIDTLVVAPKYVTRADYFEIFPDLLKEMAPPGAITDMAVVADAFVPIIKFEFSGISIDLIFSRIAMLKQLPKDFNVQDSGLLRGLDEAELRSLNGTRVTDEILSLVPEQATFKLALRAIKLWAQRRAIYANIMGFPGGVAWAMLVARVCQLYPKAASSVIVNKFFHIMRRWPWPQPVLLKHVEGGPLQVRVWNPKLYKGDQFHLMPVITPAYPSMCATYNITRSAMTVIQQELQRGCDITDAIMLGRSPWSDLFVKHTFFTQGYKYYISVITSSTDKEAHKVWSGYVESKVRVLVQGLEQHQSIALAHAFNKGYERRHRCKNEEEVHQVQAGNMSFLVRDDEDHDTSPAKDKIETKAELSSIPGLKPDPDPVPTLKTEPSDTITEVKEEGGSSATMQETPFAPVVKTELGNKTAPPIEVFTTTHYIGLTLSEGAKSLDLSYQVENFKTLCTTWEKYESTLNCLAVQHVRSFNLPDDVFEPGEKKPQRPQKRQANANGAAQIKKRSASEDNSQPPAKRQQASVTAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QR23</accession>
    <name>E3QR23_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">WD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_08455</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
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        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
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        <property type="entry name" value="WD40_repeat_dom_sf"/>
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        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44675:SF1">
        <property type="entry name" value="P21-ACTIVATED PROTEIN KINASE-INTERACTING PROTEIN 1"/>
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        <property type="entry name" value="PAK1 INTERACTING PROTEIN 1"/>
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        </source>
    </evidence>
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    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
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    </evidence>
    <sequence length="491" mass="52379" checksum="DE89451F16750FFE" modified="2011-01-11" version="1">MVAKRKRAEIAEATPAANKATAKKAKSTTNGSASKETISSAAPADELTIQIVTGSYDRVLHGITATIKPEGKVEFADTFLFSAHTSAIRCIALSPLSAPVPGQGQKVLLASGSTDERINLYNLSAHPPSRKNQELLSAVSARPILENPKNREVGTLLHHSSSITKLAFPTRSKLLSSSEDSTIAVARTRDWSVLSTIKAPIAQASGRPSGDTAPFGGTPSGVNDFAIHPSMKLMISVSKGERCMRLWNLVTGKKAGVLNFSRSMLQEVGEGRISTGEGRRVIWGKADGEDEFAVGFDRDVIVFGMDSEPKCRVMSDTRTKIHDLSYINIDGESESSLLTVSTEDGRVLFFSTATNDLKKPDSEDKTLSSAKLVAQIGGKEDGVVGRIKDTAFLQTKNDSTTALIVVAGSSDGKVRLWKVGAEELKASKSKGKGKGKAEAKQAGKLLGTYSTNNRITCVAAFTMIPRPEGVEESEDEADEASDDSDDDDDDE</sequence>
</entry>
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    </protein>
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        <name evidence="2" type="ORF">GLRG_08463</name>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
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        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EFQ33319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_008099148.1"/>
    </dbReference>
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    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08463"/>
    <dbReference type="eggNOG" id="ENOG502QQ65">
        <property type="taxonomic scope" value="Eukaryota"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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            <begin position="1"/>
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        </location>
    </feature>
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        <location>
            <begin position="49"/>
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        </location>
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            <begin position="165"/>
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        </location>
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            <begin position="185"/>
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        </location>
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        </location>
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        </location>
    </feature>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="390" mass="40738" checksum="388A8AED2F011629" modified="2011-01-11" version="1">MSGALQEDGVSAVARNKDRGWDTNVGPRHIKTPSPGTKPASPNKVAPTSPININLTVNPNTPWAAFAKDISKKPSPDRNGSQTNGGGSNGSRKSWGSKKVTDWEPIPSGQHPDLGWSTPVKSQGSIKGSNSAWAATGGNRSNSGWNTSGNVQNNDAQVNSGGDGWTTTNDTTWGDSNTNQDAWGASNNQPGDSWTNAQGNYNNWSTGSNHSGSKKSSKSQHNNSGGNRSPSGQPQLATNWNEQGNNVGYSGHVVSNDLNKPDKPSKNTSQPSTNGDWDNNAGPTTDSPVGNSNNSNGSKQGSKDTPKKRDEWASSGGSVWSTDNNAVPTNSNSPNNWGPGTTSGDNWNQTATEMSKASSGSKSMPGAWDTKLPWGDTSMAQSTGGAADNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRD6</accession>
    <name>E3QRD6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">GLRG_08703</name>
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    <organism evidence="4">
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            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
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        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
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                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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    <dbReference type="eggNOG" id="ENOG502REX9">
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR42088">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42088:SF1">
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    </dbReference>
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    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
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        </location>
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    </feature>
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        </location>
    </feature>
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            <begin position="388"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="520"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="539"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="578"/>
            <end position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ33424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="759" mass="81619" checksum="68E01149325F1E9D" modified="2011-01-11" version="1">MASASFSANGYVMGSRIPIRDVNPINMTPTPASPIRIASRIIGARDEQCTGSATLCEKPVDPASLTLPITLGVTIPIVGALFLLYYFHRRNMRRQAQEDATDPNRGLDFGLGDAPIDKGGKKRKSLMFREKGMGIETNKQRQLSMDMNLSSPYLLPPGLQSSRESLNSLARTLHNEADPYRPVYASSDAGSIYTKTTSRRGSSMTGRTTMTQNTLPPRQTSLPRPPPATADPLGASRSGSPSLPPTSPAIRSPLVAEPVIPQIETVPSGSSLPQIPDVPEPEPVAQRGLPGNSRPSPGHPTILEAREPENTPADQTNAPVGLGLDDLSFPATSHRLSPPAGGALPSSPRPQKEAAPSTLPAIVPEETNAHDRHDQDQDYQDYQDFDFEDRGRSHRRSVDDDNRQSRVLGVPAQDGKRLSVGFRPLPPDDVMESEDPEERANRIRSFYKEYFDPDNPHAAQEPPPPMPRGPHRGPQGGAQYYEDYDPGYSGGSPGGDAYFDPETNSFVMPYAQPVTRRAMTPPPNGSRFRGPPPPRGMHGSMGGGGGRMASPGPGGRRPPPRVGSGMSSGLGPSRRGSDMSSQYTPRPGSSVSNMTNGGRPKPKGPPPADLTTLPNPSKLKDDSFSILNPLDFAPPETFADRARGRSQSPSGERRPYAPKVPVHSPLVSSFEEMPAMPSPHLLRKSGTFTGLDFAPPRKFKDADTMSDAGSIRSNRSGISAVQQAAIRSGAGRISRLPGDTVFTTTALQDQLKPQWGMRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRE7</accession>
    <name>E3QRE7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08714</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697370">
        <property type="protein sequence ID" value="EFQ33435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097455.1">
        <property type="nucleotide sequence ID" value="XM_008099264.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRE7"/>
    <dbReference type="STRING" id="645133.E3QRE7"/>
    <dbReference type="GeneID" id="24414079"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08714"/>
    <dbReference type="eggNOG" id="ENOG502S0PN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061830_0_0_1"/>
    <dbReference type="OrthoDB" id="5397827at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ33435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="269" mass="29701" checksum="BDB4C58FE054818D" modified="2011-01-11" version="1">MTTSATTILPRFLLPAMGPMWRAAATSAGRPAAATLRRNTAWTIRYASSASKPTGAGQKGPLILEKPAKFNPPSHGARLPKKNGPKHYGGPLSAQEVRAQRTREYPGMMAPEGTWAHWFFNNRKIHLFISLGTLTTLAITTLTLNFTQTSPFKHLLPPASDFWSSPIEFVRTWVHVLQLHERDRNEKAIAMHSRHTDDVAKRHYYRKAHGLDKENPIANFLGMKEESEEEKAAAVAAAEASPVAGDAAAIVPVEGEGEKSNKKKWFGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRK3</accession>
    <name>E3QRK3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_08770</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 'GDXG' lipolytic enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697371">
        <property type="protein sequence ID" value="EFQ33491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097511.1">
        <property type="nucleotide sequence ID" value="XM_008099320.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRK3"/>
    <dbReference type="STRING" id="645133.E3QRK3"/>
    <dbReference type="GeneID" id="24414135"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08770"/>
    <dbReference type="eggNOG" id="KOG1515">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027519_0_0_1"/>
    <dbReference type="OrthoDB" id="5354320at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002168">
        <property type="entry name" value="Lipase_GDXG_HIS_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF25">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01173">
        <property type="entry name" value="LIPASE_GDXG_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178758" description="Alpha/beta hydrolase fold-3 domain-containing protein" evidence="3">
        <location>
            <begin position="21"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="4">
        <location>
            <begin position="159"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ33491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="478" mass="53394" checksum="0DF4068E4F237A23" modified="2011-01-11" version="1">MHPAQLKLLLSLLPKVPLMARVALLHVLHLSKSSQYLDLRSDLIVSVLRSYLQPSKPRSITSTQKLANRDNGVKGRIWVSTYASSVPETDVRDALVGAIQSLRTPDTPEIALRLPDIVPVEGEWTGYRSGATSEERQPQIGEKEKYENLQKEVTSPLTVLYFHGGAYYLLDPSSHRPTTKKIAKLTGGRVFSVRYRLAPQNPFPAALLDALISYLTLLYPPSDAYNQPVDPRHIVIAGDSAGGNLSLALLQLLLELRRQNRRIRWHGEERDILLPGGLALNSPWLDITQSSASWDVNKDFDYLPAAEVYAKHSPPPCDAWPANPPRTALYADDDLLAHPLVTLVMSRNWKGAPPVFICTGWELLADEDKYMARKLHEDGVPVVFEEYEGMPHCFSLILTTTPNARRCFDGWTGFMKRIITHPDTISSKAISVKAKTLEEVPLTFESLLSDISEEDMRQRVLKKTEASLASSPEVVPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRP7</accession>
    <name>E3QRP7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Molybdate-anion transporter</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Major facilitator superfamily domain-containing protein 5</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Molybdate transporter 2 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_08814</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697371">
        <property type="protein sequence ID" value="EFQ33535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097555.1">
        <property type="nucleotide sequence ID" value="XM_008099364.1"/>
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    <dbReference type="GeneID" id="24414179"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08814"/>
    <dbReference type="eggNOG" id="KOG4332">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_034007_2_0_1"/>
    <dbReference type="OrthoDB" id="263957at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="F:molybdate ion transmembrane transporter activity"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="P:monoatomic ion transport"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17487">
        <property type="entry name" value="MFS_MFSD5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008509">
        <property type="entry name" value="MOT2/MFSD5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23516:SF1">
        <property type="entry name" value="MOLYBDATE-ANION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23516">
        <property type="entry name" value="SAM (S-ADENOSYL METHIONINE) TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05631">
        <property type="entry name" value="MFS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="116"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="261"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="329"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="354"/>
            <end position="376"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="388"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="413"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021242"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00022989"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
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    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00030646"/>
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    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ33535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="439" mass="46997" checksum="AEDAC1FC7F1F3578" modified="2011-01-11" version="1">MLDIYQINLAGLLLACGTLFASGSRDKQNVAKKDEKKDTKQKPKKQGSQWAFYVVYALAMGSDWLQGPFLYSLYKNEHQIPSDLVPTLFTTGFVSGAVAGYFIGSLADRHGRKASCLFFCAAYALSCVLTTIPSVPLLFLGRVLGGLGTSLLFSVFESWMVTDFHARQLGDQGLDLSRTFGMMSTVNSVVAIVSGVVSEWLVSATGTRKAPFLASVGLLVVAAGVIASQWDENYGSAGQSSSAASKGKKTSLWSTMTDSRVLAIGLASTMFEGSMYLFVVLWSPVLVSASSSPETLPYGIIFASFMASTLLASLLYPRLLALVSTPSRLLLSVLFAANAVFFALGTGAPRAEQVTFWLFCLFEACVGLYFPSMGYLKGKVVDDGVRAQVYGVLRIPLNVFVVVSLMFSSEGQAGKVFLVCAMLLQASCGALWLMGGQDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRY4</accession>
    <name>E3QRY4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">3-hydroxy-3-methylglutaryl coenzyme A reductase</fullName>
            <shortName evidence="10">HMG-CoA reductase</shortName>
            <ecNumber evidence="10">1.1.1.34</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_08551</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(R)-mevalonate + 2 NADP(+) + CoA = (3S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADPH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:15989"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36464"/>
            <dbReference type="ChEBI" id="CHEBI:43074"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.34"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="10">Metabolic intermediate biosynthesis; (R)-mevalonate biosynthesis; (R)-mevalonate from acetyl-CoA: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Endoplasmic reticulum membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the HMG-CoA reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.34" evidence="10"/>
    <dbReference type="EMBL" id="GG697372">
        <property type="protein sequence ID" value="EFQ33622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097642.1">
        <property type="nucleotide sequence ID" value="XM_008099451.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRY4"/>
    <dbReference type="STRING" id="645133.E3QRY4"/>
    <dbReference type="GeneID" id="24413916"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08551"/>
    <dbReference type="eggNOG" id="KOG2480">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001734_0_0_1"/>
    <dbReference type="OrthoDB" id="310654at2759"/>
    <dbReference type="UniPathway" id="UPA00058">
        <property type="reaction ID" value="UER00103"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004420">
        <property type="term" value="F:hydroxymethylglutaryl-CoA reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015936">
        <property type="term" value="P:coenzyme A metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00643">
        <property type="entry name" value="HMG-CoA_reductase_classI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3270.10:FF:000001">
        <property type="entry name" value="3-hydroxy-3-methylglutaryl coenzyme A reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.420:FF:000001">
        <property type="entry name" value="3-hydroxy-3-methylglutaryl coenzyme A reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.770.10:FF:000001">
        <property type="entry name" value="3-hydroxy-3-methylglutaryl coenzyme A reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.770.10">
        <property type="entry name" value="3-hydroxy-3-methylglutaryl-coenzyme A Reductase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3270.10">
        <property type="entry name" value="HMGR, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.420">
        <property type="entry name" value="Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025583">
        <property type="entry name" value="HMG-CoA_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002202">
        <property type="entry name" value="HMG_CoA_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023074">
        <property type="entry name" value="HMG_CoA_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023076">
        <property type="entry name" value="HMG_CoA_Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004554">
        <property type="entry name" value="HMG_CoA_Rdtase_eu_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023282">
        <property type="entry name" value="HMG_CoA_Rdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009023">
        <property type="entry name" value="HMG_CoA_Rdtase_NAD(P)-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009029">
        <property type="entry name" value="HMG_CoA_Rdtase_sub-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053958">
        <property type="entry name" value="HMGCR/SNAP/NPC1-like_SSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00533">
        <property type="entry name" value="HMG_CoA_R_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10572">
        <property type="entry name" value="3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10572:SF24">
        <property type="entry name" value="3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00368">
        <property type="entry name" value="HMG-CoA_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13323">
        <property type="entry name" value="HPIH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12349">
        <property type="entry name" value="Sterol-sensing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00071">
        <property type="entry name" value="HMGCOARDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55035">
        <property type="entry name" value="NAD-binding domain of HMG-CoA reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56542">
        <property type="entry name" value="Substrate-binding domain of HMG-CoA reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00066">
        <property type="entry name" value="HMG_COA_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00318">
        <property type="entry name" value="HMG_COA_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01192">
        <property type="entry name" value="HMG_COA_REDUCTASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50065">
        <property type="entry name" value="HMG_COA_REDUCTASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 10" id="KW-0521">NADP</keyword>
    <keyword evidence="7 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="296"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="375"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="400"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="484"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="12">
        <location>
            <begin position="241"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="667"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1138"/>
            <end position="1185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1141"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1169"/>
            <end position="1185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ33622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1185" mass="127576" checksum="17AD128F35D7C7BE" modified="2011-01-11" version="1">MISSTLLPRRFRGEQPAVPPAAPSWVNKKITPALKFLSKLACSHPIHTVVIVAVLASTSYVGLLQESLFDATISVRTADWSSLLEGSRILHAGPETSWKWQNVEPDASISGEVDHQALLTLVFPDSQSPESANTAPRTHAVPIPQNLSITSLPSTSNSLTSYSQDSALAFSVPYSQAAEFLSVAQEIPDATSDEIETKHGKEKKMWIMKAAKVHTRNSFVQWARNGWTEFLDLLKNAEALDIFIMVLGYLSMHLTFVSLFLSMRRMGSNFWLFTNVLFSSVFAFLFGLFVTTKLGVPITMVLLSEGLPFLVVTIGFEKNIVLTRAVLSHAIEHRRPLASKEDKKSNKSDVSSPNVIQYAVQAAIKEKGYEIIKDYAIEIGILVLGAASGVQGGLQQFCFLAAWILFFDCVLLFSFYTAILSIKLEINRIKRHVQMRRALEDDGVSHRVAEHVAKSNDWPEFNGKAPKEASLFGKQMKSSNVPKFKVLMVSGFVLINAINICTIPFRNSSSLPSLASLTGGLSAVVTAPPVDPFKVASNGLDSILESAKAGERPTVVTVLTPIKYELEYPSIHYALPSPASKSGHKLDDEYDHFDSYGVGGRMVGGILKSLEDPVLSKWIIVALAMSVALNGYLFNAARWSIKDPNVPDQQIDPKELARAEKFNDTDSATLPLGEYIPPTPKPVTPASTDDESELAMTQTKSSDEASSPVEKRTIAQLEKMIAEKRVHEMTDSEVVTMSLRGKIPGYSLERALKDFTRAVKIRRSIISRTNATSDLTNGLERSKLPYQNYNWERVFGACCENVIGYLPLPVGVAGPLVIDGQSYFLPMATTEGVLVASASRGCKAINSGGGAVTVLTGDGMTRGPCVSFETLERAGAAKIWLDSEAGQATMKKAFNSTSNFARLQSMKTALAGTNLYIRFKTTTGDAMGMNMISKGVEHALSVMASEGFEDMSIVSVSGNYCTDKKAAAINWIDGRGKSVVAEAIIPGDVVKSVLKSDVDTLVQLNVDKNLIGSAMAGSVGGFNAHAANIVAAIFLATGQDPAQVVESANCITIMKNLRGSLQISVSMPSLEVGTLGGGTILEPQSAMLDMLGVRGPHPTTPGENSRRLARIIAAGVLAGELSLCSALAAGHLVRAHMQHNRSAPPTRSSTPAPASGSMTPVGLAMTSTAEKAASKSAAAVERARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSM2</accession>
    <name>E3QSM2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_09004</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697374">
        <property type="protein sequence ID" value="EFQ33860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097880.1">
        <property type="nucleotide sequence ID" value="XM_008099689.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSM2"/>
    <dbReference type="STRING" id="645133.E3QSM2"/>
    <dbReference type="GeneID" id="24414369"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09004"/>
    <dbReference type="eggNOG" id="KOG1231">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018354_1_1_1"/>
    <dbReference type="OrthoDB" id="2151789at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF53">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="5">
        <location>
            <begin position="9"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ33860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="454" mass="48326" checksum="447C750D63DBA153" modified="2011-01-11" version="1">MESYWSVSAALNPWCIAQPSTAEDVSTIIKTLATFNCTFGVRGGGHGSFAGSNSVEEGVTIDFGNMNSTIYDNNTKLASIQPGGHWQTVYDTLAPHGVVVTGGRAGTVGTGGFITGGGNSLHSASHGFACDTVANFEVVLADGSIVNANATSNPDLWQGLKGSGANLGLVTRFDMHVIDFPDPSKPVVWGGKLYYDLESGPQVIDAFVDFVENVQKDENSSSIVYWGYVPANGGMFLNAAIQNTLAEVAPPVFDGYYTAGSIIRDTTKVALMSVAASELGSNSPGGLRNVWFTLAFANDARIMNYAVQKYSALNEDLEKAIGASGFNTLCMFQPITKSIVDKGVANGGNILGLEHYIDKGNGIMFLITLAINGADNETTAFPYVQDFVEDVESYAASLDLGWGWKFLNYAHKLQDAISSYGDPSIEKLRAASAKYDPTGVFQNLRQSGFKIPPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSW0</accession>
    <name>E3QSW0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_09092</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697375">
        <property type="protein sequence ID" value="EFQ33948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097968.1">
        <property type="nucleotide sequence ID" value="XM_008099777.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSW0"/>
    <dbReference type="STRING" id="645133.E3QSW0"/>
    <dbReference type="GeneID" id="24414457"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09092"/>
    <dbReference type="eggNOG" id="ENOG502SNI4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_3_5_1"/>
    <dbReference type="OrthoDB" id="5022096at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF167">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="99"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="176"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="252"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="37"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="322"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="367"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ33948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="398" mass="44576" checksum="B4EC61948B575B74" modified="2011-01-11" version="1">MSSTTNVDPARAKESNTEMILAVTGFFHALALLFVGLRTYTRVLIVKSMGIDDYVIIMSALCALGGGMVVFIVQSFYGLGKHKDTISKVDNILFLKVGFFQSIISAIAALALLKISIAMSLLRLSKNKWYSRALWALIAFVILYTIMAWLSFFLYCTPMEGYWDRSLKPKCYPLKLFINFALVNTSFNIFTDVCFATLPIPIIWVLQMKLRTRIYLVGILSLGYLAVIMGIVKAFFQIAQPNNKDSTFLQSIQFWGFLQLNLGIIAACAPSLRPLVGRALKLNSGRLYNNANLYENRYPTGPTGRTVIITASAKRQGYMEQSSQSAPEFELEEGTFSQSADTRRQESIRGKSRLGAVSVYRKNSLEDRSGSEEMILDTDSRTPGSRGIMRTTEVHIER</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>E3QT59</accession>
    <name>E3QT59_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">GLRG_09191</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="GG697376">
        <property type="protein sequence ID" value="EFQ34047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098067.1">
        <property type="nucleotide sequence ID" value="XM_008099876.1"/>
    </dbReference>
    <dbReference type="SMR" id="E3QT59"/>
    <dbReference type="STRING" id="645133.E3QT59"/>
    <dbReference type="GeneID" id="24414556"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09191"/>
    <dbReference type="eggNOG" id="KOG0920">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001832_1_3_1"/>
    <dbReference type="OrthoDB" id="5600252at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17917">
        <property type="entry name" value="DEXHc_RHA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000819">
        <property type="entry name" value="ATP dependent RNA helicase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000500">
        <property type="entry name" value="ATP-dependent RNA helicase DHX29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1080:FF:000002">
        <property type="entry name" value="Putative ATP-dependent RNA helicase DHX36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF145">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX57-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="693"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="940"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="233"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="321"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="385"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="630"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="51"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="276"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="390"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EFQ34047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1490" mass="165311" checksum="B8347537939F2831" modified="2011-01-11" version="1">MAGAKKKKKPAANPARGFATTSVASSKPRTEPAEGPDNGAAVRSATAAPNAVSNQDAPPSDPQSASAGAGDKATKAELTPEEFEKQLDESELQLLVEKYAQKTKRDAQRQRTRLETDRRLLRSQADTVNSRKWLPQELMDQVLDLIQAESRFASSSVSTETAVSGKLLPEEDMIIKLWTLQQTLTGVGFPEERVQAVMRHILDIAPNIPSTAKDSLWGLEEALDWMARECPSDELPDYEGRGKQGTRQLDTPAESPLPSGATTPRASEPGGRQKGGQRSKNGGSATSKKKTVVTCDSDIEPDDLVPVYLVTKAKLFELERSQQGKKKQRNGDSGSDEGAETLDKLRAKIDRIDKDVLFDKFAAEQQWRTQKVALEKEIAAARKQKSLEQAQKEAERDTEGPVASSDGDINDEAERIAAEVLAQGEDDEDGGLSDLFANLPVSEVDAAGKSSIVLNGADGVKITIRDFGKWTGVSPMRALEEACRARDPAVKVTYRLISEVPFANRHAVSISWSRSQETPPPSQDDSVEVGTYPSIFNFTMKSVATPDSKQSEAYVATWALFHIFGTSAKEEKVGMRLPVAWRDLWDELAEARKSQLDAKDREAIRELRALVRQRQDQELEDGVILQSAFKGRGTARNQNEKGDESSQEAAKRLSGGPEYYQNIWAQKTNSPRYQAMLQGRMQLPMWNFKQQVTDAVDREQVVIVCGETGCGKSTQVPAFLLEHQLTQGKPCKIYCTEPRRISAISLARRVSEELGEGRGDLGTSRSLVGYSIRLEANTSRETRLVFATTGIVMRMLEGSNDLREVTHLVLDEVHERSIDSDFLLIILKKLMLRRKDLKVVLMSATVDAERFSKYLGGAPVLTVPGRTFPVQVRYLEDAIETTGYTVGQASQEKMVDLDDDVVETEVERPKSIAGADLSAYSAKTRNSLAQMDEYRIDFDLIVQLIAKIASDSEYVAYSKAILVFLPGIAEIRTLNDLLSGDPSFARDWLIYPLHSTIATEDQEAAFLVPPPGMRKIVLATNIAETGITIPDVTCVIDTGKHREMRFDERRQLSRLIDTFISRANAKQRRGRAGRVQDGLCFHLFTKHRHDTIMSDQQTPEMLRLSLQDLAIRVKICKIGGIEETLSEALDPPSAKNIRRAVDALIDVRALTPAEDLTPLGNQLARLPLDVFLGKLILMGAIFKCLDMAITVAAILSSKSPFTAPFGQRAQADLVRKGFRRGDSDLLTVYNAYLSWKRVCQSTSASGGKDFQFCRKNFLSQQTLANIEDLKGQLLVSVADSGFLLLTDDERRALNRLRYGANSRGRRHQNFFDIPQRVSINSENDAITTAVVAWSFYPKLLVRDNLGSRGLRNVGNNQSISLHPSSVNKGHNELKWLSYYHIMQSKSVYHAHETSAADPFAIALLCGDVRADMFSGVLVLDGNRCRFALPDWKTMLVIKVLRTRLRELLTRSFKQPGKLPTAQHERWLAIWQKIFSQEANKDNGNTTVSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTB5</accession>
    <name>E3QTB5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_09247</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MSOX/MTOX family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697376">
        <property type="protein sequence ID" value="EFQ34103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098123.1">
        <property type="nucleotide sequence ID" value="XM_008099932.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTB5"/>
    <dbReference type="STRING" id="645133.E3QTB5"/>
    <dbReference type="GeneID" id="24414612"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09247"/>
    <dbReference type="eggNOG" id="KOG2820">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007884_0_2_1"/>
    <dbReference type="OrthoDB" id="2219495at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051698">
        <property type="term" value="F:saccharopine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008115">
        <property type="term" value="F:sarcosine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045170">
        <property type="entry name" value="MTOX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10961:SF37">
        <property type="entry name" value="FAD DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10961">
        <property type="entry name" value="PEROXISOMAL SARCOSINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="8">
        <location>
            <begin position="179"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="419"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ34103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="438" mass="48986" checksum="DC2A1B78826D0313" modified="2011-01-11" version="1">MDQREHTSYLIVGAGVFGVSTAYHLIKKYPGASVTLVDKDAFDADERVAASWDWNKVVRADYDDFTYCQLALEAQDIFKSDPLWKPFFHQTGVYWICRSDYAQNVIDHHKKLGRKDDIIALPVSEARKLYGGLFEDADYSGAKEVLVNRASGWAAAGDCLRAVTREAVRLGVKYVTAETASLEFDERGSCTGIKTTTGETLAADHTILSTGAYTPKLLELSAAESGLANLRAGDRILAAGITTGMAELDEDEYKQYANMPVGFQGYTGHGKPFIGSIPPTKDRELKWWGAKIFTNTKEILPGRHVSAPPPAKDYSQWKVSRQLKQDIAEQRDLWYGSKSANWKMTKHRICWDAFTTSSDFIISPHSAAKGLYLATCGSFHGFKFFPVLGKYVVQMLEDSLSPELKTRWAWDRERPDHLQNPEYPNSELSDLLDPVSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QU38</accession>
    <name>E3QU38_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_09520</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697379">
        <property type="protein sequence ID" value="EFQ34376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098396.1">
        <property type="nucleotide sequence ID" value="XM_008100205.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QU38"/>
    <dbReference type="GeneID" id="24414885"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09520"/>
    <dbReference type="eggNOG" id="ENOG502S731">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025399_0_0_1"/>
    <dbReference type="OrthoDB" id="5204190at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507:SF13">
        <property type="entry name" value="MFS GENERAL SUBSTRATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507">
        <property type="entry name" value="ZGC:174356"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="214"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="280"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="319"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="430"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="463"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="499"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ34376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="538" mass="57901" checksum="E75441FE0B6E00A7" modified="2011-01-11" version="1">MAVDADERTPLLKVGAGAVKRVGRGLWSPANRILFAGFLVSLTLGITQVPIIYVFRVMACETFYNGRAPFDGPAADMCHRREIDANTARQVSILGMTTSVCGILNLFICGDLIKRWGTRWALISQTGLLCIRVSCQIIAVSTGGQRGIDLMQYTQLIGIVGGPRGYMLVLNTAVAEVVERRKHTGVFGRLQGAVMIGTAIGYLLGGVLGDVFGIVSPFVTAVGCFAVATTYGAIFWPAPPEQNDESATKTTPGASGFLAPIKVLMPQKYRLESGKVVRNYGLVFLALGIFFGVFATGYAPILIQMYATSRFNFGTTENGILMSGNSWIRGIFLMFIFPEIIDAGRRWFAASSHSGALQKTLTQEERNLIPTHPEDMDPVPGLMNAAEPTKAPPEEEDEDSTFDLFFLRWSLVVDGIVTSLAAWATKGWHVYAAAFLLPFASGSAPAAKGVITEMCPPHMRQDALSAITLVESAATLTTQGIFGLVFATLSEMGKPNLTFFVNAALAVVAVGVLLLAHYPPPNAKRLEDEEAEDNSVQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QU52</accession>
    <name>E3QU52_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_09534</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697379">
        <property type="protein sequence ID" value="EFQ34390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098410.1">
        <property type="nucleotide sequence ID" value="XM_008100219.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QU52"/>
    <dbReference type="GeneID" id="24414899"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09534"/>
    <dbReference type="eggNOG" id="ENOG502T4I6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1069610_0_0_1"/>
    <dbReference type="OrthoDB" id="10658815at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="19"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="201"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ34390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="260" mass="28388" checksum="053CADCD0DD6291F" modified="2011-01-11" version="1">MAIIDNAVFGGLLYGGCGYAFLGLVTYTVVNMGGLLALPAWYTGSARGPKERVLLALWFPAIVALWPLVLPPWLAARFGRRACEWLRVMGRRARSRGRRLCCGGGDGSVDLESGGEISLDEGRRWARLGFFVNPFEDRGRSRSRARDGRPEVSENRSPMDRGADGSAAGSEQQQKQQQRPLPLPPTTWYTKLPSPEEMQRARAQASSGGSSAPPASLPQVADNVVYPDPAGRSEVLRRLQTIHEDKGGELGGGWEDVRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUZ2</accession>
    <name>E3QUZ2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_09824</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697382">
        <property type="protein sequence ID" value="EFQ34680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098700.1">
        <property type="nucleotide sequence ID" value="XM_008100509.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUZ2"/>
    <dbReference type="GeneID" id="24415189"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09824"/>
    <dbReference type="HOGENOM" id="CLU_2596480_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ34680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="80" mass="8817" checksum="E97B3404096F603F" modified="2011-01-11" version="1" fragment="single">SLSLTLSHSLSLSLTLSHSLSLSLTLSHPLSSTLTLLSSRTHPTGTRVQRALLLEFQLARTSLVLHFPRFHRPILAAYTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUZ3</accession>
    <name>E3QUZ3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_09825</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697382">
        <property type="protein sequence ID" value="EFQ34681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098701.1">
        <property type="nucleotide sequence ID" value="XM_008100510.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUZ3"/>
    <dbReference type="GeneID" id="24415190"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09825"/>
    <dbReference type="HOGENOM" id="CLU_2256391_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ34681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="104" mass="11566" checksum="AC2E846955B18045" modified="2011-01-11" version="1" fragment="single">RDIELSELENFLPLPCSARVGWGPPSLYYLYLPIRTDTVPWNQEILEHRVFSPCLVRNLKTDHDQSGTDQHSQVAQAKSQSIFDGVVGVKGGDEAGKVEADKCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QV03</accession>
    <name>E3QV03_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Choice-of-anchor B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09837</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697383">
        <property type="protein sequence ID" value="EFQ34693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098713.1">
        <property type="nucleotide sequence ID" value="XM_008100522.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QV03"/>
    <dbReference type="STRING" id="645133.E3QV03"/>
    <dbReference type="GeneID" id="24415202"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09837"/>
    <dbReference type="eggNOG" id="ENOG502QQSB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031217_0_0_1"/>
    <dbReference type="OrthoDB" id="2099887at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027589">
        <property type="entry name" value="Choice_anch_B"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04312">
        <property type="entry name" value="choice_anch_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38787">
        <property type="entry name" value="REGULATORY P DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38787:SF3">
        <property type="entry name" value="REGULATORY P DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179975" description="Choice-of-anchor B domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="557" mass="60617" checksum="8E4E4C6A5B56BDA4" modified="2011-01-11" version="1">MVRASSYLGSLAVLAASAVAKEIQPNEALAAELYDSGKIHEQVIASKKAEFARQKAAGAYNSEVWPELGYTPCVNGWAEAVVGDRNNTFRCHNADLYSFLSHAALGGPLAEGSSSWGWTNDDGREFVAIGQYEGTAFAEILSDGKLVYLGRLPQYSSPSEWREIRSYKHYMVIGSEAVGHGIQIFDMKKLLDIDPASPIVFDAKLDLTSHFNTLLPLGRAHNVVVNEELNYAVAVGAMPRTDPLCAAGLNFFDLTDPANPVSLGCAKGDGYVHDAQCLVYRGPDKRYEGRDICYGYNEDTLTIYDVTDKANVTNIISRISYEGASYTHQGWVLDVNNQEFLVLDDELDESRGNGPAAEGYPVTFIWDIRDLENPKQTGTFTHPTKAIDHNQYVIDNYIYQSHYGAGLRVLDGTSIPSDPTGAGVCEAAWFDIYPEDDDFEGGGYVGFVGTWSSYAYFPSGYIFINTIERGAFVVKLTGKDCPKAPVCNADNCLRSFRATSVPGRLEESQAFCKSFLSSPIKDAAVLPEHAVTNCAKEDKVAQASSACACLPTATAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QV48</accession>
    <name>E3QV48_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">D-amino-acid oxidase</fullName>
            <ecNumber evidence="8">1.4.3.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_09882</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a D-alpha-amino acid + O2 + H2O = a 2-oxocarboxylate + H2O2 + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:21816"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:35179"/>
            <dbReference type="ChEBI" id="CHEBI:59871"/>
            <dbReference type="EC" id="1.4.3.3"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:21817"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Peroxisome matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DAMOX/DASOX family.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.3" evidence="8"/>
    <dbReference type="EMBL" id="GG697383">
        <property type="protein sequence ID" value="EFQ34738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098758.1">
        <property type="nucleotide sequence ID" value="XM_008100567.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QV48"/>
    <dbReference type="STRING" id="645133.E3QV48"/>
    <dbReference type="GeneID" id="24415247"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09882"/>
    <dbReference type="eggNOG" id="KOG3923">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034311_1_0_1"/>
    <dbReference type="OrthoDB" id="409956at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005782">
        <property type="term" value="C:peroxisomal matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003884">
        <property type="term" value="F:D-amino-acid oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019478">
        <property type="term" value="P:D-amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.9.10:FF:000018">
        <property type="entry name" value="D-amino acid oxidase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006181">
        <property type="entry name" value="D-amino_acid_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023209">
        <property type="entry name" value="DAO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530">
        <property type="entry name" value="D-AMINO ACID OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530:SF16">
        <property type="entry name" value="D-AMINO ACID OXIDASE (AFU_ORTHOLOGUE AFUA_5G11290)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000189">
        <property type="entry name" value="D-aa_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00677">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="11">
        <location>
            <begin position="9"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="44"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>D-dopa</name>
            <dbReference type="ChEBI" id="CHEBI:149689"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>D-dopa</name>
            <dbReference type="ChEBI" id="CHEBI:149689"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00039101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000189-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ34738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="374" mass="40869" checksum="2CA514255457ECFF" modified="2011-01-11" version="1">MHSLTVSSAGVSGLTAALLLSKSRANSVTVIAKHMPGDYDIEYTSPWAGANVLPMAPESDSRWERRTWPELKRLAAEVPEAGIHFQKSVVFRREVDAASSSPYDALYAVDPWYRDLLPDFRDLRADELPANAHSGSEFTSVCINTALYLPWLVGQCRKNGVVFKRGVIAHIRELKALHHSGKPADIIVNSSGLLACKLGGVEDKKVLPARGQVVVVRNEIEPMATISGTEDGPTEVCYMMTRAAGGGTVLGGTYDKGNWDPNPDPNIANRIMKRCVELSPALTGGKGVEALDIIRHGVGLRPYREGGVRMEIDKSTFEDGTPIVHNYGHAGWGYQGSYGCAERVVELVNQIRAEKGERLSNEPKMFSWDRASKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QV96</accession>
    <name>E3QV96_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09928</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697384">
        <property type="protein sequence ID" value="EFQ34784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098804.1">
        <property type="nucleotide sequence ID" value="XM_008100613.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QV96"/>
    <dbReference type="GeneID" id="24415293"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09928"/>
    <dbReference type="eggNOG" id="ENOG502SSHC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098343_0_0_1"/>
    <dbReference type="OrthoDB" id="2151982at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="234" mass="25227" checksum="FAF699669EA31336" modified="2011-01-11" version="1">MADKTSTRDDDVARGFIDEGFSQDGDEEPSPPSFIPLPLPQLTDEPQALPDCCLSLSLPLLRELHGLLPPAPHLTLSIGSGTGLVEGLLHALASSSSSLSSSSPPHAMLNLVSVEVAPSPNRYHVAHRTVPGTWALDPLAGEARAWVFVYPKQVALVRDYMAAFSGGKGCAVETVVYIGPRRDWDDFRAAFEGFARDVEVWDEEKMEAAGGRAWECLAVVRPEKRGRSPSPPDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVB6</accession>
    <name>E3QVB6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_09948</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697384">
        <property type="protein sequence ID" value="EFQ34804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098824.1">
        <property type="nucleotide sequence ID" value="XM_008100633.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVB6"/>
    <dbReference type="STRING" id="645133.E3QVB6"/>
    <dbReference type="GeneID" id="24415313"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09948"/>
    <dbReference type="eggNOG" id="ENOG502SIYQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_0_0_1"/>
    <dbReference type="OrthoDB" id="3934549at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF151">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="82"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="157"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="195"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="234"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="62"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="327"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="455"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="393"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ34804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="479" mass="53340" checksum="E170CEE0BF53AB98" modified="2011-01-11" version="1">MAAAAMMAYYPYDDMSIDEPERGYLKKLADLAEQQNLEEDMRSYVRAVTIAFTVLATVVVGLRFTSRHLQNAKYLIDDYTMLAALAILIGNMIMNLILVEGGIGLHSGRLNLEQTQFLNRTMIGAEILYVNGVNMYKVALLLLYLRIFPMREVRKGALICGSLTTGWTLACVIAASIQCLPIVKVWEPWRPGYCINLFLTQLCISVPSIIVDIAILYLPIPHVLKLQMNRAQRVLVLFTFLLGSYVVFCSIYRFKIFLGYTPDDVPYSLAQGLAWNIIELSSGIVSACLPTLGPIVRLLWKGLLDTAQRSGLDKYARSISTNKKSGSRSAALTIGGGQRSGTASQARDGSKDWSKLSEPNNKANNFREEAKYGIGLRTMGGGDDDRSSRSSNEVDVTPQNSVSVTIKSPGASSFRERDQNMSARDYYHGKRLTRQQSTSNYSQSNNMIWQHREIEITTEPVEPESMIPEPSSKRRSGLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVN2</accession>
    <name>E3QVN2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_10064</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697385">
        <property type="protein sequence ID" value="EFQ34920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098940.1">
        <property type="nucleotide sequence ID" value="XM_008100749.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVN2"/>
    <dbReference type="STRING" id="645133.E3QVN2"/>
    <dbReference type="GeneID" id="24415429"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10064"/>
    <dbReference type="eggNOG" id="ENOG502QQSW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015256_5_1_1"/>
    <dbReference type="OrthoDB" id="2316594at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ34920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="486" mass="52633" checksum="1029DC231C3D1E66" modified="2011-01-11" version="1">MAGKPTPDTDGVFSETEPQADIVVQLKHLALEPQTQYNDEVVSSPLLTVPLIDRSPPSQFGLFGASISGGVTSLEATRLFHNVACPSSVFICGSQGSGKSNTLACLLENCLIPSQLGQLPHPLTGIVFHYDSFVSDSGGLPCEAAFIASHEQASVRVLCAPTNVRTIQKIYSGIPNVTIKPLKLSDDDLNTRRMNDLMAVGEGGSMPLYLHVVNRILRDMRMKQQRTGLGFSYAEFRRLLGREDLTPGQLNPLNQRLDTLESFMAKETLGCSGQLTVVDLSCPCVTAELACSLFNICLSLFLEQQSPIGRVVALDEAHKYMKESGESQALTNALLETIRLQRHLGVRVLISTQEPTVSTKLLDLCSMTVVHRFTSPDWLRTLGKHLAGISSMSVTVTDEEDEVQAVSPIPIGGKDPMMEVFSMIVSLHTGQALVFAPSAVLALHGKGVSEPAVLQRLAHRALRVMVRSRLTRDGGRTVMAIGDSTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVS7</accession>
    <name>E3QVS7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Thaumatin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_10109</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697386">
        <property type="protein sequence ID" value="EFQ34965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098985.1">
        <property type="nucleotide sequence ID" value="XM_008100794.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVS7"/>
    <dbReference type="STRING" id="645133.E3QVS7"/>
    <dbReference type="GeneID" id="24415474"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10109"/>
    <dbReference type="eggNOG" id="ENOG502S0AX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043181_7_0_1"/>
    <dbReference type="OrthoDB" id="430315at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.110.10">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037176">
        <property type="entry name" value="Osmotin/thaumatin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001938">
        <property type="entry name" value="Thaumatin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31048">
        <property type="entry name" value="OS03G0233200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00314">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00347">
        <property type="entry name" value="THAUMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00205">
        <property type="entry name" value="THN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49870">
        <property type="entry name" value="Osmotin, thaumatin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51367">
        <property type="entry name" value="THAUMATIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ34965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="415" mass="45104" checksum="9FDA90A493D10410" modified="2011-01-11" version="1">MTMRRSSSRKVDKRSNKASRNLLVALALASQLPTTNGIVFPSYHPSYKSDYLQLNKRYNPAKRGPPEDWNGRIPLKITNSCPGTIWPGITTQHGIGPGTGGFELASGDSRDLWVGPTWQGRAWGRTNCTVNGESAGCATGDCFGKLDCEFSGTVPATLAEFNLAGGVSGRQTFYDISLVDGYNLPVGINYIPAENTTFIPPNLTNCACIATPGFMAQRAASGAVYTNSTFPVPWEPNESNDSVRDWCPWPLLTNPPDKPGDGVYPYPDDQIRRPTFSPCKSQCAATNSDHDCCIGKWHDPDKCKPGLFSRHAKAMCPDAYSFAFDDQTSTFIVPSGGGWEVVFCPAGRSTNILRTMGPQLFEIASAGFLSQKNLELVRNRTYIESESAKNAASGHAVLSHWAICAIITAVLLIEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QW53</accession>
    <name>E3QW53_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alpha amylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_10300</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697388">
        <property type="protein sequence ID" value="EFQ35156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099176.1">
        <property type="nucleotide sequence ID" value="XM_008100985.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QW53"/>
    <dbReference type="STRING" id="645133.E3QW53"/>
    <dbReference type="GeneID" id="24415665"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10300"/>
    <dbReference type="eggNOG" id="KOG0471">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024572_2_0_1"/>
    <dbReference type="OrthoDB" id="550577at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11318">
        <property type="entry name" value="AmyAc_bac_fung_AmyA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013776">
        <property type="entry name" value="A-amylase_thermo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006968">
        <property type="entry name" value="PRK09441.1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006969">
        <property type="entry name" value="PRK09441.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43447">
        <property type="entry name" value="ALPHA-AMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001021">
        <property type="entry name" value="Alph-amls_thrmst"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="7">
        <location>
            <begin position="11"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ35156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="509" mass="58095" checksum="D2AC26D2C37E1372" modified="2011-01-11" version="1">MGDQEPTPENHTMMQGFEWYVPADQKHWVRLEKHVPQLKQFGVDNIWIPPACKGSSKTGNGYDIYDLYDLGEFDQKGSVATKWGTKEELLQLAHTAKDNGVGIYWDAVLNHKFAADRKEKCLAAEVDPEDRTKFVSDQYEIDAWVGYDFPGRDGKYSDMKYHWYHFSGVDYNARNEKTAIYKILGDKGDQQWADSVDSEKGNYDFLMGSDLDYDHPEVVNDVLNWGKWLAKEVPLKGIRFDAIKHYSEDFLRQFITELDKEYGQGWFFVGEFWKDSLDDMSEYLARMGRRFTLFDAPLVYNFSEISKGDGADMRKVFDGTLVQKEPINAVTLVMNHDTQPYQALEAPIEGWFKPIAYALILLRTGGYPCVWYGDIYGIKGEHPFPPSCGGAVPKMTLARKLYAYGKQADYFDYATCLGWVRYGTWDRPFGCAVVASNAGPGSKRMHVGEMHAGEVWTDVLGWNDREVTIGDDGFGEFVCSGTSVSIFVNREAGGREKFNKEFDSNIYEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>E3QX75</accession>
    <name>E3QX75_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Nucleoporin autopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_10607</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleoporin GLFG family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697393">
        <property type="protein sequence ID" value="EFQ35463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099483.1">
        <property type="nucleotide sequence ID" value="XM_008101292.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QX75"/>
    <dbReference type="MEROPS" id="S59.A07"/>
    <dbReference type="GeneID" id="24415972"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10607"/>
    <dbReference type="eggNOG" id="KOG0845">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002330_0_0_1"/>
    <dbReference type="OrthoDB" id="3797628at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044614">
        <property type="term" value="C:nuclear pore cytoplasmic filaments"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008139">
        <property type="term" value="F:nuclear localization sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000973">
        <property type="term" value="P:post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006405">
        <property type="term" value="P:RNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034398">
        <property type="term" value="P:telomere tethering at nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1610.10:FF:000003">
        <property type="entry name" value="Nucleoporin SONB, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1610.10">
        <property type="entry name" value="Peptidase S59, nucleoporin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025574">
        <property type="entry name" value="Nucleoporin_FG_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037665">
        <property type="entry name" value="Nucleoporin_S59-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007230">
        <property type="entry name" value="Nup98_auto-Pept-S59_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036903">
        <property type="entry name" value="Nup98_auto-Pept-S59_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021967">
        <property type="entry name" value="Nup98_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23198:SF6">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP98-NUP96"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23198">
        <property type="entry name" value="NUCLEOPORIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04096">
        <property type="entry name" value="Nucleoporin2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13634">
        <property type="entry name" value="Nucleoporin_FG"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12110">
        <property type="entry name" value="Nup96"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82215">
        <property type="entry name" value="C-terminal autoproteolytic domain of nucleoporin nup98"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51434">
        <property type="entry name" value="NUP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="6" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="9" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Peptidase S59" evidence="12">
        <location>
            <begin position="927"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="344"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="678"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="740"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="821"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1076"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="156"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="358"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="391"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="409"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="420"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="438"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="456"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="480"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="498"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="521"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="553"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="563"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="573"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="622"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="649"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="678"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="740"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="846"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1101"/>
            <end position="1114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1132"/>
            <end position="1141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1144"/>
            <end position="1155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ35463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1972" mass="206045" checksum="0F27F3BB6949388A" modified="2011-01-11" version="1">MSGFGSTGFGGFGSTNNQQSTGFGGFGASNNSGTPSTGFGSGNTTNNAFGSASNTSTGGGLFGAGGNTTSAFGGTPSGGFGSNTSTAFGAAKPAFGATPSTGGGLFGAPNTSNNTATTSTFGGFGANTTANTSSPFGGASSGGGLFGGANKPAFGSTTNTSTPSTTSLFGGGNTSGGFGSTTTAAGGGFGASMNPGIGSNVGDPPGTALTPFQAHQEKETTGAGNQSNSFQNILFQEPYKKWSSEELRLADYAQGRRHGNASGTGAFGVSNFGSGGFGSTTNQPSSGFGTGASAGGGLFGGGSNTANTSTTSGFGGGSAGGFGSGGGGLFGNNAAKPATGGLFGGGTTATSQPTQSGGLFGGGASTGGFGTTGTTGGFGSTNTNTGGGLFGSNTNNTTQNKPAGFSFGNTGGGTTGGFGSTTNSGFGANSNTTNNTGSTGGLFGNAGQSAGGGLFGNNQSQPQQQNTGSAFGGGGGFGAQPQQTSGGLFGNNQQKPAAGGGLFGGGGASSTGGGLFGGGSTTSNTFGTTNTNNTTGGGLFGAKPTATGGGLFGSNTTGQNTNSGGGLFGGSLGANNQQQQQQQQQTGQSSLFGGGQNQTKPGGLFGSAQPAGGSLFGGQNTQQQGSLFGNNNQQQQQQPQNSFLGGSLLGNSQGVNAGPQSLTASINDVSAYGSPSLFSNLGGSETPNPGPLATPLSSKSKPRRSSILPMYKLNPASAARYATPQKRGFGFSYSTYGTPGASPSSAASTPGGTSRSLLGSSSMNRSLSKSVSTSNLRRSFNTEDSILAPGAFSASSGPRYYGQNGSVKKLIINKDMRSDLFSTPTKEKPSSDHVNSSRKLSKRVSFDTSTMDASEGSNENDTTSTPRGDAVTQKAAPAGVSVNGTTSAAGTPEGLDPSKGKELAIVHEEDASSQPPEDHKEGFDAAPGAYWMSPTKEVLASMNRVQRQQVTGFTVGRDNVGSVQFKVPVDLTNIDLDEIFGGIVILETRSATVYPIAAKKPPVGKGLNVPATISLEQSWPRGRDKRPSNDAKRFHKHVERLKRIENTTFESYDTETGIWKFSVEHFTTYGLDYDEDEDEAEQPANEPSRDDASFSNVSQQDSDDSESSPQEDDTFDFRRSKRRALPGAFDYRDEDFDEVEDTQPPAQRQSFLGDSFAGSTSNALILSTEEEADDQDIGYGMSEDEDTAGTPLRRHLAAEQRSESPESDAAAPVIETPGGILRARMRALKGSATPIKLQVAGGDEWMDMLQRSVSPQKRDRALLRSVNEAALRPTVEEVETTEQKSRVVSDGRGFATSIDLMNSLFEKAKAPAPSAPAPSRGFVQWPYERQTKSFVDQSDMSDADRSFYNSMRPSWGPDGTLIFASTRSSLEGAGRQNMADSLMITKNVIQAQGREIQSAKFSNESSAKTLENQIQMTRAELAGGILELSLHPTTLKSLFHDQDASNPTNMHEKLVWELASILFDTVGTVDRTAEARSRRNNLSQFWAALVDSASSRSIALARSGEEKAIAALSGHRIQDACKYLIDGKNFRLATLVSLIGSNDESKKDMREQLSEWQDANFLSEFADPIRAIYELLSGNSCVCEGKKGVPLEDRIESFVISKRFGLDWKQAFGLRLWYSISREDDISAAVRIFQDDVAQGREQRPQTWFVEQGIPALWQDQDQDQREDLLWGLLKLYADEQADLEAVLRPENSQLSPFDVRLSWQLSRALLSTNKVSYGPDATEKADALTISFADQLINEGSWLEATFVLLHLSQPEMRAKDVQDNLCRHASLLGPETGINFMTLTQTLKIPAAWIWEAQALYMRAVKKDASAEVQCLLRAGSYAEAHDVFVRKVAPSAVISRDYDELTAILSRFEGHDDDIAGWTLGGEIYKAFLELVNRRRQRQQALSPVLEKLVAGLPAMRENAESAHITSLAAISEMGSTVAKVMAEASRQEQDVPRVLGLPLTEDAHLKHSLHLGLSYYRGLMAGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXX5</accession>
    <name>E3QXX5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_10868</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697398">
        <property type="protein sequence ID" value="EFQ35713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099733.1">
        <property type="nucleotide sequence ID" value="XM_008101542.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXX5"/>
    <dbReference type="GeneID" id="24416233"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10868"/>
    <dbReference type="HOGENOM" id="CLU_1796326_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ35713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="144" mass="15466" checksum="FEAB2F6CCDF1276C" modified="2011-01-11" version="1">MTDKYDCKSIGCVAQERFGGTRAGSGTAGDFRRSWLMRPSAVDPLELRKQGTGVTDLLGTLNIQQLPRAYGVEVRSTADREQRAWQSKQDLAGAAACRGIRSKASTTSWLAVLPTGTASGEPSTEYLVRMVSYLLSSIHDAPGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYB1</accession>
    <name>E3QYB1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10958</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697401">
        <property type="protein sequence ID" value="EFQ35849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099869.1">
        <property type="nucleotide sequence ID" value="XM_008101678.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYB1"/>
    <dbReference type="GeneID" id="24416323"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10958"/>
    <dbReference type="eggNOG" id="ENOG502SBG2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099958_2_0_1"/>
    <dbReference type="OrthoDB" id="5274873at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00048">
        <property type="entry name" value="DSRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="117"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="127" mass="14370" checksum="AFF40F23B3F3662D" modified="2011-01-11" version="1">MGGFYMQYLESLCRRRGWMDPTYECYRDHNGYTCLVLVNGREYQTDLAYESDSLAQENAAMRAFMVCRNFSVNGGMLARNGIVQGLPATETPRRSKKSRHTSSSHSSRDSHRRSGHHSSSSSTASFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYD6</accession>
    <name>E3QYD6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11065</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697402">
        <property type="protein sequence ID" value="EFQ35874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099894.1">
        <property type="nucleotide sequence ID" value="XM_008101703.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYD6"/>
    <dbReference type="GeneID" id="24416430"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11065"/>
    <dbReference type="HOGENOM" id="CLU_1948682_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="129" mass="14758" checksum="CC8D6DC3591D0181" modified="2011-01-11" version="1">MLSRYLDELTTYAETVSDDVEARFESLTIYSADGSDAGDVWETCQNEDSRERNNCVSSRPNSPDIHDLWYQIRRNGTERAAQPPHEELKEEDSAGYSKTFDSDGLEKSRVRRILARVAKLVGQMEPRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYE9</accession>
    <name>E3QYE9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_11078</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697402">
        <property type="protein sequence ID" value="EFQ35887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099907.1">
        <property type="nucleotide sequence ID" value="XM_008101716.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYE9"/>
    <dbReference type="GeneID" id="24416443"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11078"/>
    <dbReference type="eggNOG" id="ENOG502T544">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_894316_0_0_1"/>
    <dbReference type="OrthoDB" id="4851285at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ35887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="311" mass="33440" checksum="6C1AB67F429429C4" modified="2011-01-11" version="1">MASPSSRDEGVQINSFTAVASDQQTSSFKTRSNEPGRNKGKGPITRNREKSLVRLCSSRGAMPTIPEIRVKGPDSRDVRIGAGGSVSPSSHPQSTDHLQVPNSSKPRAQQKQQTVQAGVGRKRTFLGFVDCALGLQHVRTCGDHEPLVGRRYRAKRNTFRIIALFGVLMMLSLAASITLFVYFASTGGAGPEWFAWIAISAAGWICSLLAFIMAKQSERRALHDVEIARQSTRLSSRVQDGTAAPVAIVGGPGANRQHVMPAGSSAATGAPPAVFGRYRALEFIHEEDEALDAEHRLDMLVANQRPRGGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYN9</accession>
    <name>E3QYN9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Alpha-galactosidase</fullName>
            <ecNumber evidence="2 6">3.2.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_11121</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.</text>
            <dbReference type="EC" id="3.2.1.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the glycosyl hydrolase.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.22" evidence="2 6"/>
    <dbReference type="EMBL" id="GG697405">
        <property type="protein sequence ID" value="EFQ35977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099997.1">
        <property type="nucleotide sequence ID" value="XM_008101806.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYN9"/>
    <dbReference type="STRING" id="645133.E3QYN9"/>
    <dbReference type="GeneID" id="24416486"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11121"/>
    <dbReference type="eggNOG" id="ENOG502QWG1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009640_2_1_1"/>
    <dbReference type="OrthoDB" id="5795902at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004557">
        <property type="term" value="F:alpha-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14791">
        <property type="entry name" value="GH36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1180:FF:000028">
        <property type="entry name" value="Alpha-galactosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000118">
        <property type="entry name" value="Alpha-galactosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.60">
        <property type="entry name" value="alpha-galactosidase from lactobacil brevis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038417">
        <property type="entry name" value="Alpga-gal_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050985">
        <property type="entry name" value="Alpha-glycosidase_related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002252">
        <property type="entry name" value="Glyco_hydro_36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031705">
        <property type="entry name" value="Glyco_hydro_36_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031704">
        <property type="entry name" value="Glyco_hydro_36_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43053:SF3">
        <property type="entry name" value="ALPHA-GALACTOSIDASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43053">
        <property type="entry name" value="GLYCOSIDASE FAMILY 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16874">
        <property type="entry name" value="Glyco_hydro_36C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16875">
        <property type="entry name" value="Glyco_hydro_36N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02065">
        <property type="entry name" value="Melibiase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005536">
        <property type="entry name" value="Agal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00743">
        <property type="entry name" value="GLHYDRLASE36"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180033" description="Alpha-galactosidase" evidence="9">
        <location>
            <begin position="26"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 36 N-terminal" evidence="11">
        <location>
            <begin position="84"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 36 C-terminal" evidence="10">
        <location>
            <begin position="668"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="505"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="567"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="383"/>
            <end position="384"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="470"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="503"/>
            <end position="507"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="545"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="567"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR005536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR005536-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR005536-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ35977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="746" mass="82659" checksum="2943A148779C03BC" modified="2011-01-11" version="1">MAGYCRFICLVVAAFAAVLTGQVLAQNSSANGIVVDGKSFALNGDHSSYRFHVDELTGDLYSDHFGGPATESMAMLPPATNGWVGMMGRVKREYPDLGRGDFRIPALQIRQSEGYTVSDLQYRSHRVAQGKPGLPGLPATFGNEDEVSTLIVSLYDNYSSIAVDLSYSIFPKYDAIVRSVNITNEGQGNITIDKAAALSIDLPFADMEMIELRGDWAREAMRLRRKVDYGTQGFGSTTGYSSHLHNPFLALVFPETTESQGEAWGFSLVYTGSFSVEVEKGSQGFTRAMLGFNPYQLSWPLGPGETLTTPEVVAVYSQTGVGGLSRKYHRLYRNHLMRGQYVDQTRPALLNSWEGLYFDYNASTIYELAQEAAQLGVKLFVLDDGWFGKEYPRINDTAGLGDWAFNPDRFPDGMPALVNKVVDLQVANSSDKLSFGLWFEPEMVNPNSTLYRTHPDWVLHAGNYPRTERRSQLVLNVALPEVQEFIIESVSNILSSAPISYVKWDNNRGFHETPTPGIGHSYMLGIYHVFEVLTSRFPNVLWEGCASGGGRFDPGILHYFPQIWTSDNTDALDRIFIQFGTSLAYPPAAMGAHVSAVPNHLTGRTIPIKFRAHVAMMGGSFGLELNPADISKEDKAQIPGLMALSELVNPIVIRGDLWRLSLPEDSNWPAAMVISEDSSQAVLFYFQIRSFYNHALPRLRLQGLDPEESYSLDGNGTYSGATLMSTGVQYDFEGDYDSRVVMIQRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QYR3</accession>
    <name>E3QYR3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">WD repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11145</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697406">
        <property type="protein sequence ID" value="EFQ36001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100021.1">
        <property type="nucleotide sequence ID" value="XM_008101830.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QYR3"/>
    <dbReference type="STRING" id="645133.E3QYR3"/>
    <dbReference type="GeneID" id="24416510"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11145"/>
    <dbReference type="eggNOG" id="KOG2919">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022731_0_1_1"/>
    <dbReference type="OrthoDB" id="239865at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051150">
        <property type="entry name" value="SWT21/TCAB1_mRNA_Telomere"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13211">
        <property type="entry name" value="TELOMERASE CAJAL BODY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13211:SF0">
        <property type="entry name" value="TELOMERASE CAJAL BODY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="458" mass="49697" checksum="8953BB0B47486250" modified="2011-01-11" version="1">MSAMHPSENNDADPLPHHQMTTWDKDPYAPLMHLVATTDITTTHSAAQLRPTSFFRRLQWTADGTALVASTSDNRLSTYVLPADLLDKNSSPRTLTPQGQLHLPEPFYSAAISPYFSLSEPHTQLALLACKDHPIQLHHVFPDSPSSHPLCSYKLIRRETEEYICPESIMWSWPGTHFLTGSMNRLDHFDMSRPGSDGPVLTIPTIPSKRHLLKGGGVGMKGMVSALSSQSPDEPGTSIVAAGTWSRWMGLYDVTRTNKPVANWSIHGVTKAHFGREIGGNGIVQTIWSPCGRYLAINERQASGILVYDVRGTGQPLNLLVGRNTTTQQRLTCDVFPGTGDVSGGFELWAGTESGSLLIYENVGACDGVLDKSWDWAAHSSPVGSAALHHTGSVVATCSGSWTSHADHELDNELGCADGNGQPRLASTRITPDSSLKVWTLATDIADPDTLTEDQPDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZ25</accession>
    <name>E3QZ25_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_11257</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697409">
        <property type="protein sequence ID" value="EFQ36113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100133.1">
        <property type="nucleotide sequence ID" value="XM_008101942.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZ25"/>
    <dbReference type="GeneID" id="24416622"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11257"/>
    <dbReference type="HOGENOM" id="CLU_2687689_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ36113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="74" mass="7644" checksum="6B78A1F5A104EB90" modified="2011-01-11" version="1">MAILPKLRAKRQGTLVSLTSSVLANQLGGRNELLRIAVLSWACRVRGLASPSVALLAVSCLGSIVNGWAAATTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZ66</accession>
    <name>E3QZ66_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NADH:flavin oxidoreductase/NADH oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_11298</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697411">
        <property type="protein sequence ID" value="EFQ36154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100174.1">
        <property type="nucleotide sequence ID" value="XM_008101983.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZ66"/>
    <dbReference type="STRING" id="645133.E3QZ66"/>
    <dbReference type="GeneID" id="24416663"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11298"/>
    <dbReference type="eggNOG" id="KOG0134">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012153_0_0_1"/>
    <dbReference type="OrthoDB" id="276546at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003959">
        <property type="term" value="F:NADPH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02933">
        <property type="entry name" value="OYE_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000059">
        <property type="entry name" value="N-ethylmaleimide reductase, FMN-linked"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893:SF129">
        <property type="entry name" value="FLAVIN OXIDOREDUCTASE HXNT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="NADH OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="4">
        <location>
            <begin position="19"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ36154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="410" mass="45209" checksum="60556BE1AB1282BC" modified="2011-01-11" version="1">MPKATTPPPAFAALKDTALFTPLKLGSFSLKHRIVQAPTTRMRSEFESRGVNVPGTRVAKYYGERASEGGLQITEATDICLNASAYPGVAGVFTDSQLQGWRKVTDAVHSKGGFIFVQLWHTGRASSAGMRGGNTPVSSGSQPMDGKYLDGTECKDGPPRPLSVDEIHNLTAEWAAASKRAVDVAGFDGVEIHGANGYLLEQFLHDNINDRTDEYGGSIENRSRFLFEVLSAVSAAIGPEKVGLRLSPYNYFQGTRDSDPNKHWSYISQRLAELPDSQRPAYVHMIEPRFDEVLDEEQKLASLCGSKPESKPANNLTQFRDILKPSGIRFFAAGNFNRDNALSKVKSGESDAVVFGRHFIANPDLVERLKNGWPLNPYDRTTFYGAEPPEKGYNDYEFYRVDNAEIMVNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZQ3</accession>
    <name>E3QZQ3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Stress-induced bacterial acidophilic repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11486</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697419">
        <property type="protein sequence ID" value="EFQ36341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100361.1">
        <property type="nucleotide sequence ID" value="XM_008102170.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZQ3"/>
    <dbReference type="STRING" id="645133.E3QZQ3"/>
    <dbReference type="GeneID" id="24416850"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11486"/>
    <dbReference type="eggNOG" id="ENOG502STRE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_122062_0_0_1"/>
    <dbReference type="OrthoDB" id="2137750at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019626">
        <property type="entry name" value="Stress-induced_KGG_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052590">
        <property type="entry name" value="Stress/Virulence-Domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36569">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36569:SF5">
        <property type="entry name" value="CONIDIATION-SPECIFIC PROTEIN 10 (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10685">
        <property type="entry name" value="KGG"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="157" mass="16061" checksum="3D4580B3E54E0DE6" modified="2011-01-11" version="1">MADNNPGNFANRPTEEVRQIAAKGGHASHGGGITQNQSSGTDNTNPGNFANRPKEEVREIAAKGGHASHGGGITQNQSSGTDNTNPGNFANRPKEEVQEIAAKGGHASHSGGFASMDADKQRQIASEGGKASSGSFEPGSERAREAGRKGGLHSSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0E6</accession>
    <name>E3R0E6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_11717</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697440">
        <property type="protein sequence ID" value="EFQ36584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100604.1">
        <property type="nucleotide sequence ID" value="XM_008102413.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0E6"/>
    <dbReference type="STRING" id="645133.E3R0E6"/>
    <dbReference type="GeneID" id="24417081"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11717"/>
    <dbReference type="eggNOG" id="ENOG502T4QH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1128980_0_0_1"/>
    <dbReference type="OrthoDB" id="5308957at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ36584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="246" mass="28351" checksum="19A6BBD37BB63C25" modified="2011-01-11" version="1">MLNAKKPGMPITAMAKTTHAIFLESLAQFSHSLEQLCDVTADCFIATRGSDDLKSLYARQVALVSGNSHEISISDIENVLEIYSDLWDEAVGLFGENLYEAMTVEWYRIRAMEWLSYDGFEHSCERYIRRIQTKNGCHWHDWDPEYLNDVAYMLRYLAQFHEDADNFDSCIFYSEECIRMLNYLVEKHGSFAGYRPRAVEVQLELIEVLSKLGRLQEASEVRLNVAGSGYLREVVDNDVECESLEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0N7</accession>
    <name>E3R0N7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Linoleate diol synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_11821</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697460">
        <property type="protein sequence ID" value="EFQ36675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100695.1">
        <property type="nucleotide sequence ID" value="XM_008102504.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3R0N7"/>
    <dbReference type="GeneID" id="24417184"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11821"/>
    <dbReference type="eggNOG" id="ENOG502T6P5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002329_3_0_1"/>
    <dbReference type="OrthoDB" id="823504at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.640.10">
        <property type="entry name" value="Haem peroxidase domain superfamily, animal type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019791">
        <property type="entry name" value="Haem_peroxidase_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037120">
        <property type="entry name" value="Haem_peroxidase_sf_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050783">
        <property type="entry name" value="Oxylipin_biosynth_metab"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11903:SF13">
        <property type="entry name" value="LINOLEATE 10R-LIPOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11903">
        <property type="entry name" value="PROSTAGLANDIN G/H SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03098">
        <property type="entry name" value="An_peroxidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50292">
        <property type="entry name" value="PEROXIDASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="344"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="562"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1410"/>
            <end position="1432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="576"/>
            <end position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ36675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1432" mass="161323" checksum="DB2CB784CA1AB09E" modified="2011-01-11" version="1">MATRAIAVAQSREDQLMDLTLQLRNKENEKKYAQFHGDSLISNKITQKVGPLGDLTAAFAPSNWRAWVNIAGSFFSGKGLDERGFAQIAGSLSNHSTFREEFLINAQVREKYNKMLHPPLTYLGDAFQYRTADGSFNSALNPHLGQAGAPYAKTVPSKTAPLGALPDPEVLFDRLMARENGGRQSQSGLSSMLLYHATIIIHDIFRTNDNDKNLSDSSSYLDLSPLYGYTEEMVRKVRDNKYKLGLLKPDTFAEDRLLRQPPGVCIMLVMYNRYHNYAARQLLQINENGRFSVPEMYSGARLVALIKEHLPDQDDHGNKVPLDPKVERLCNKYERLWSEVQAARPADAPDAALPQQGPETPEQTALREAAAEKRKNALDLITSFESQPLYREFVDVKRKLKQKLKEKGQKLERESPALLKSFENNCKDFKIAWQAACDKQDDDLFNTARLITQGMYVNISVHDYLRALMGFHQFDTNFTLDPRKDFDQKKTTRGIGNQVTVEFNLIYRFHCAISLRDEKYVEDFMKATLGIEKPDSLSLPEFLKVMAYGKQKHEEPWQVTFGIPDAPATKTSPGLEDGHSTERSRNGSDSGISMDGISVGVDTNKAMEAPAVATASVANSKLFTRNDITNLFDDEQMLNELTAAMDEPLSNFGPRNVPKCLKPVEIMGIMQARKWEIGTLNDFRSFFELPVHTTFESVSANTDIQNALRDLYESPDKIELYPGIFCESDVMMGLDPGPGNSSSALWSAIFSDAITLVRSDRFYTVDWNTQSLTAWGMKEVTPDNDVCKSSVFHRLIQRAFPGWLPPDSLRWFSPFYTAKQNAIYAEQQGYAVQFGETANIELNPCYDHAKAAASIVAYPPKKPQKPCYLDNFDDIFTVLKGYQSDHFTNPVFTYKSNLPQSLRDVLDRETVRPINFDRKILENYVKNSEKDLKAYLSELMTFIVKRESVSITNSEFQIDATRDFAIPVVTRYMASFLGFSHKLREIPDTSTVWDKHTKAAHRGTYTENEIYQHITNCQVFLAYNTDETKWMARRRAFQKSVEFLIDLATHGTIWEANQIFGLSNMLFGKEENNPMHRMGVFVARQVLKHEPNRVRAAAILLLISLDFAYNAVVSFSATLDGFMEDLCQVANGDNIAAEPKWLALQRAALADDDATVEKMVQGMARNKVNLPIVRKVLKEGQFDFVGDGSHKGSPTTLKEGQYVVLDLAPATAIAEEAKDKGKLEFLTLQLSIADKYAVFSPRRFTPLSQAQMIKFIALTRNTRRGPAAQGELKRVHLEPTLEGYANYMAPGRVEWIKKQVGELEDRRKASRIFNDKVFRPGFDTYLTPAWDEYVPFPMTWKIRFDGFGKSDYIDKKGVKYGQIRTVGKKLPDFCPPWYQPKGQSSDGGAFAVVKCVCTDSVTSGCSCGGGKAGRKETAPKPVAMSTGCRGPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3R115</accession>
    <name>E3R115_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_11949</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="GG697554">
        <property type="protein sequence ID" value="EFQ36803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100823.1">
        <property type="nucleotide sequence ID" value="XM_008102632.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R115"/>
    <dbReference type="STRING" id="645133.E3R115"/>
    <dbReference type="GeneID" id="24417312"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11949"/>
    <dbReference type="eggNOG" id="KOG3855">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_14_2_1"/>
    <dbReference type="OrthoDB" id="2690153at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004780">
        <property type="entry name" value="PRK06126.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF19">
        <property type="entry name" value="BINDING MONOOXYGENASE, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="21"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ36803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="526" mass="57631" checksum="AEE7974ECDDE2F27" modified="2011-01-11" version="1" fragment="single">MTNTSLSESQSDNHRNSDVIDVLISGAGPVGLALALDLGRRGVRSTIIEKKPEISTQILAKASVLDERTMEYCRRLGIRDAVVNSGYPADLPADTIYCTSFDGHYIGRLEMPSALEREIPEQTCEMMRRCPQMLFDPILARAVKEQGMATVRYSSEVVSAEQDADSVTCAVKHVDTGSIEYIRGRFVVACDGASSFLRKTVDIGFEGQDLGFAFSAIVLIQDLHSYHNFGAAAERYLFIGPEGTWANFTTIDGHDLWRFTVAGSGERVDPDTVDLKGILRKAIGREDVPFEILRVNQWRRSQYTASKYRSGRIFLAGDSAHTMSPTGGHGLNTGLGDASDLSWILQAVLGGWGGPEILDAYEIERRPVAIRNGVLSSRNFGLWKERQGRDKVLDSGPVADEQRRVLGTTLALHMRQEFQSIGLALGYNYAHSPVVVTDGSPAPEDQPDLYIQTARPGHRAPHFWLEDGRSSLDIFGQGFVLLAFGTGAGTMGESLQSAASALRLPLKCVEIKESSGAQLYQRKLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q234</accession>
    <name>E3Q234_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00279</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089155.1">
        <property type="nucleotide sequence ID" value="XM_008090964.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q234"/>
    <dbReference type="GeneID" id="24405644"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00279"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2236395_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="105" mass="11350" checksum="0D4429BDF4053F1F" modified="2011-01-11" version="1">MVILGLLSTNVAGGHEAVGRLGLGIAGPQFFKSTEAPAYHDGIVAMLCGFILNLVLNQVLRLIYAAENKRRDRLLEGKSEGEIADMQREGEVLGFEDVTDKANVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2D1</accession>
    <name>E3Q2D1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ZIP zinc/iron transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_00376</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ZIP transporter (TC 2.A.5) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089252.1">
        <property type="nucleotide sequence ID" value="XM_008091061.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2D1"/>
    <dbReference type="STRING" id="645133.E3Q2D1"/>
    <dbReference type="GeneID" id="24405741"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00376"/>
    <dbReference type="eggNOG" id="KOG1558">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027089_0_2_1"/>
    <dbReference type="OrthoDB" id="448280at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000007">
        <property type="term" value="F:low-affinity zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071578">
        <property type="term" value="P:zinc ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004698">
        <property type="entry name" value="Zn/Fe_permease_fun/pln"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00820">
        <property type="entry name" value="zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040:SF69">
        <property type="entry name" value="ZINC-REGULATED TRANSPORTER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040">
        <property type="entry name" value="ZINC/IRON TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="319"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="358"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="155"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="170"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="203"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ25232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="380" mass="40658" checksum="2B59BBC0B8BA0669" modified="2011-01-11" version="1">MNPLEISAVKLLALRQDEGAGADEAVNACGAAAVDVSNMPLRIAAIFVILIASLFGSFLPICLARTSRMHVPKMTFFIFKYIGTGVIIATAWMHLLSPGVEALHNECLAPMLGDYDWAFAIGLMTVMVMFLIEMVASNLASSAFSHGHDHDLGQGPVAVKSNEQTTESDACPHEIGDAERGNGFIDPQKVPGLPDDVSYPPGGRDHLGHARDHKEGDSHSGLAGQLIAIFILEFGVVFHSIFIGLVLATSDELVVLLIVLTFHQCFEGLGLGSRLATADWPSHGRWWPHILATIYGLSTPLAIAVGIAARPSSAQTQTLVNGIFDCISAGILMYTGLVELLAHEFMFNPQMRNSPLKVQLFAFGCVALGACVMAILANWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3U2</accession>
    <name>E3Q3U2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_00838</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089714.1">
        <property type="nucleotide sequence ID" value="XM_008091523.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3U2"/>
    <dbReference type="STRING" id="645133.E3Q3U2"/>
    <dbReference type="GeneID" id="24406203"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00838"/>
    <dbReference type="HOGENOM" id="CLU_2026546_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ25694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="122" mass="13375" checksum="CEEA9D4699AD52CC" modified="2011-01-11" version="1">MLARAVFDNSLADIATKLDVAAVARAEAEAWPAEYVRQLSSARNWDVNDDASAAAAPDQAFRESRLETFTRFRVGVSQDAGTYRDLLLVDVEDREGPNVSREVRHEGFFESVVEVGDGDGVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q405</accession>
    <name>E3Q405_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Mov34/MPN/PAD-1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_00901</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M67A family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089777.1">
        <property type="nucleotide sequence ID" value="XM_008091586.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q405"/>
    <dbReference type="STRING" id="645133.E3Q405"/>
    <dbReference type="MEROPS" id="M67.A11"/>
    <dbReference type="GeneID" id="24406266"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00901"/>
    <dbReference type="eggNOG" id="KOG1555">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052991_0_0_1"/>
    <dbReference type="OrthoDB" id="605656at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
        <property type="term" value="C:nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008541">
        <property type="term" value="C:proteasome regulatory particle, lid subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034515">
        <property type="term" value="C:proteasome storage granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140492">
        <property type="term" value="F:metal-dependent deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000266">
        <property type="term" value="P:mitochondrial fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032436">
        <property type="term" value="P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043248">
        <property type="term" value="P:proteasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902906">
        <property type="term" value="P:proteasome storage granule assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd08069">
        <property type="entry name" value="MPN_RPN11_CSN5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000001">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050242">
        <property type="entry name" value="JAMM_MPN+_peptidase_M67A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056263">
        <property type="entry name" value="RPN11_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10410">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23594">
        <property type="entry name" value="RPN11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102712">
        <property type="entry name" value="JAB1/MPN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-0647">Proteasome</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="9">
        <location>
            <begin position="34"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="309"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="309"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ25757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="337" mass="37812" checksum="E977181C20BE5105" modified="2011-01-11" version="1">MERFRNMLQSQGLGGLGGQSGTDNTQLIDNSETVYISSLALLKMLRHGRAGVPMEVMGLMLGEFVDDFTVRVVDVFAMPQSGTGVSVEAVDPVFQMKMMDMLRQTGRPEAVVGWYHSHPGFGCWLSSVDINTQQSFEQLTPRAVAVVVDPIQSVKGKVVIDAFRLINPQSLMLGQEPRQSTSNLGHLNKPSIQALIHGLNRHYYSIGINYRKTALEENMLMNLHKHVWTEALEMNDFRHEANCNKERLESLVSLAEGYEKRVKEETELTKDQLKTRYVGKLDPKKHLEDVGQQLIEDNIVSVSRQMIDKEATMPKKDAPAGTKDHSNGDSMDVEEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4I2</accession>
    <name>E3Q4I2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_01141</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090017.1">
        <property type="nucleotide sequence ID" value="XM_008091826.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4I2"/>
    <dbReference type="GeneID" id="24406506"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01141"/>
    <dbReference type="HOGENOM" id="CLU_1906587_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ25997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="133" mass="14845" checksum="73CA72930263C515" modified="2011-01-11" version="1">MVVEEPGFSVSQWAGVFDLPKIIADLRCARATSINKIMESPSLDEFSLDSTEILWKPTMDVLLEEEEIKSKARVGYSSNGESLGCYVLERIVKPMTYQPLHNSVKEGPSLKMTGLLLVMIKAPSLTWARKHCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4J5</accession>
    <name>E3Q4J5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome P450 6A1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_01154</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ26010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090030.1">
        <property type="nucleotide sequence ID" value="XM_008091839.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4J5"/>
    <dbReference type="STRING" id="645133.E3Q4J5"/>
    <dbReference type="GeneID" id="24406519"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01154"/>
    <dbReference type="eggNOG" id="KOG0684">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033574_2_0_1"/>
    <dbReference type="OrthoDB" id="1055148at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00302">
        <property type="entry name" value="cytochrome_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050529">
        <property type="entry name" value="CYP450_sterol_14alpha_dmase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24304:SF2">
        <property type="entry name" value="24-HYDROXYCHOLESTEROL 7-ALPHA-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24304">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="289"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="452"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ26010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="515" mass="57676" checksum="2E307F4DD859CAC7" modified="2011-01-11" version="1">MSAAAVASTALRPHDWPMGVWVLLLTGLAYAVGALVHRPSFPNSAPRLFKSYPVVGSPRFFSKRGNFLSEGRRLAESGNWSFYFGKKRIVGLSGLEGRRLFFESRELDFAKGYGALLNATPEINLSSGERSSDDNFDAKFNRSLVRLLRKDVLSQRLHLLVSDARGTMDDLAARIGPSSEFGTSDPFEDMYRLVFQLTVRMVGCDEVAEDPVLLLRMLRIFEGIDGAATATKVMFPWMPTVGHLRRVISGARMYRILDGVIQERKARGVPGNDALQFLMDNGDSTIEMVAFLVGALFAGLINTGINAAYLLCFLAGDAHWYGEFQREVDGVIARRRRSAEQAADEILASMTMDEWEAEFPLIDLGLKEVIRHTLTGCGFRYNGSGKDLPIGKTGEVVPQDAYVVYQFDSTHMDPEFFTDPSRWDPGRYLPGREEDKKDPHAFIGWGTGRHPCLGMRFAKLEMAVTTAMFISRFDFYLADANGNKMDRVPESSIDRNRHSAAKPREKMFLKFKPRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4R0</accession>
    <name>E3Q4R0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">SAP domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_01219</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the SAP domain-containing ribonucleoprotein family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ26075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090095.1">
        <property type="nucleotide sequence ID" value="XM_008091904.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4R0"/>
    <dbReference type="STRING" id="645133.E3Q4R0"/>
    <dbReference type="GeneID" id="24406584"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01219"/>
    <dbReference type="eggNOG" id="KOG4259">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063282_0_0_1"/>
    <dbReference type="OrthoDB" id="445357at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052240">
        <property type="entry name" value="SAP_domain_ribonucleoprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040746">
        <property type="entry name" value="THO1_MOS11_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46551">
        <property type="entry name" value="SAP DOMAIN-CONTAINING RIBONUCLEOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46551:SF1">
        <property type="entry name" value="SAP DOMAIN-CONTAINING RIBONUCLEOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18592">
        <property type="entry name" value="Tho1_MOS11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAP" evidence="4">
        <location>
            <begin position="5"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="18"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="47"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="61"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="132"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="176"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="223"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00046328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ26075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="251" mass="26609" checksum="1785F3110056AD83" modified="2011-01-11" version="1">MATDYSSLKVPELKKLLQERGLPATGNKLDLVNRLKENDKQTAPATAEEDEIDYSDDEPAPAKAPEAPKPAADASAPATAEPTAPAAEAAPEAAPEAATTAEGDEPDKAAETAAEVPKENFALNLDATDAAAEAKKRADRAKRFGIDEDKEAKKKAERAKKFGVEVGSVAGLDSALPERRPKRGRPERADEQPGRNSKRLSTDGRGQRGRGNRNGRPGGRQGGGDREPRRSAAVDPADKAKMEARAKRFAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q527</accession>
    <name>E3Q527_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00938</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089814.1">
        <property type="nucleotide sequence ID" value="XM_008091623.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q527"/>
    <dbReference type="STRING" id="645133.E3Q527"/>
    <dbReference type="GeneID" id="24406303"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00938"/>
    <dbReference type="eggNOG" id="ENOG502RJPK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_148217_0_0_1"/>
    <dbReference type="OrthoDB" id="5422107at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="110" mass="12214" checksum="343E9A65CE796473" modified="2011-01-11" version="1">MPSVKNPNGPSKNRLANRALVAKMERKKKSEANRHKIAKTDAMRGARPGLAPTSGPNAPLSKKKAKKLEKKMAHALRRKMAAEGEVVMKDVEEAEERKPEEGDMETEKIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q580</accession>
    <name>E3Q580_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cell wall protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00991</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089867.1">
        <property type="nucleotide sequence ID" value="XM_008091676.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q580"/>
    <dbReference type="STRING" id="645133.E3Q580"/>
    <dbReference type="GeneID" id="24406356"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00991"/>
    <dbReference type="eggNOG" id="ENOG502RPSB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056393_0_0_1"/>
    <dbReference type="OrthoDB" id="2422134at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021054">
        <property type="entry name" value="Cell_wall_mannoprotein_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38123">
        <property type="entry name" value="CELL WALL SERINE-THREONINE-RICH GALACTOMANNOPROTEIN MP1 (AFU_ORTHOLOGUE AFUA_4G03240)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38123:SF6">
        <property type="entry name" value="CELL WALL SERINE-THREONINE-RICH GALACTOMANNOPROTEIN MP1 (AFU_ORTHOLOGUE AFUA_4G03240)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12296">
        <property type="entry name" value="HsbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178212" description="Cell wall protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="189"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ25847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="324" mass="30196" checksum="2BE46A2F05145BCB" modified="2011-01-11" version="1">MQLTKTLLFALIGTAFAAPTEKRQASVIQSAVTSVQDAITKLDTAVKGVGDDISTAQPVLAAATDLQNVITKAGSDIGASQPLQLQEALGLQNLASQLQTTTGTLIDDLISKKANFDKLGVSKVVLQNLQQQKSTVQSLGTSLISKVPAIGQGIAQQAIDGVGATIDKGIQAYSGSAAAAAVDSAPVAAEPGDSTAASPAAAPATPESPASAPKTPVTAQEATDATPAGGIGSLLGGLGGAGGAGGLSLLGGLTGGAAGGAGGTGGAGGAGGLGALLGLLGGAGAGGGAKGGGAGGAGGLGALLGLLGGGAPKGKVADVAEAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q583</accession>
    <name>E3Q583_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Helix-turn-helix-domain containing protein type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00994</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089870.1">
        <property type="nucleotide sequence ID" value="XM_008091679.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q583"/>
    <dbReference type="STRING" id="645133.E3Q583"/>
    <dbReference type="GeneID" id="24406359"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00994"/>
    <dbReference type="eggNOG" id="ENOG502SRAW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090929_1_0_1"/>
    <dbReference type="OrthoDB" id="3724345at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="entry name" value="dinb family like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018531">
        <property type="entry name" value="DUF1993"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36922">
        <property type="entry name" value="BLL2446 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36922:SF1">
        <property type="entry name" value="DUF1993 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09351">
        <property type="entry name" value="DUF1993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="DinB/YfiT-like putative metalloenzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="80"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="173" mass="19001" checksum="81B0D98349050A68" modified="2011-01-11" version="1">MSSITVYDAVIPLFINGLKTFDHILSKAEEYAKANNIDANTYPEARLVEDQLPLTFQVQNATKTVKTNVGRLTGVELEPFENKEKTIEDLHKRIEEALDLLSKVDAATVNAKADDQVDLPIFGGKTLKVSAKEAALSHGVPNFFFHLNAGYAILRSKGVPVGKADYLGSFLNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q614</accession>
    <name>E3Q614_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Coatomer subunit zeta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_01406</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 12">Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 12">Golgi apparatus membrane</location>
            <topology evidence="1 12">Peripheral membrane protein</topology>
            <orientation evidence="1 12">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Cytoplasmic vesicle</location>
            <location evidence="12">COPI-coated vesicle membrane</location>
            <topology evidence="12">Peripheral membrane protein</topology>
            <orientation evidence="12">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the adaptor complexes small subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090282.1">
        <property type="nucleotide sequence ID" value="XM_008092091.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q614"/>
    <dbReference type="STRING" id="645133.E3Q614"/>
    <dbReference type="GeneID" id="24406771"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01406"/>
    <dbReference type="eggNOG" id="KOG3343">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086803_0_0_1"/>
    <dbReference type="OrthoDB" id="10249988at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd14829">
        <property type="entry name" value="Zeta-COP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000013">
        <property type="entry name" value="Coatomer subunit zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039652">
        <property type="entry name" value="Coatomer_zeta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11043:SF0">
        <property type="entry name" value="COATOMER SUBUNIT ZETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11043">
        <property type="entry name" value="ZETA-COAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 12" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6 12" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AP complex mu/sigma subunit" evidence="13">
        <location>
            <begin position="49"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00045555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU366053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ26262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="200" mass="22079" checksum="C2DA509DCC23DF82" modified="2011-01-11" version="1">MAPGMSLFSVNAILILSIEDGSRLFSKYYSAPHAGSATQNGSSNSSGNPYPDVKSQKAFEKGLLEKTAKQTGDIILYDNRIVLYKMESDVMMYVVGGVDENEVLLYNVILALRDSLHLLFKQSVDKRTIVENYDLVSLAIDEIVDDGIILETDPTIIVQRVSKAPAQDVDLRRIDLSEQGVNNLAQLGKSKLADWLRQGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6D8</accession>
    <name>E3Q6D8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Nitrate/nitrite transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_01530</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090406.1">
        <property type="nucleotide sequence ID" value="XM_008092215.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6D8"/>
    <dbReference type="STRING" id="645133.E3Q6D8"/>
    <dbReference type="GeneID" id="24406895"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01530"/>
    <dbReference type="eggNOG" id="ENOG502QPIC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024204_1_1_1"/>
    <dbReference type="OrthoDB" id="434240at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015112">
        <property type="term" value="F:nitrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015113">
        <property type="term" value="F:nitrite transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044772">
        <property type="entry name" value="NO3_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004737">
        <property type="entry name" value="NO3_transporter_NarK/NarU-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00886">
        <property type="entry name" value="2A0108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23515">
        <property type="entry name" value="HIGH-AFFINITY NITRATE TRANSPORTER 2.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 8" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="158"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="389"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="414"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="447"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="480"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ26386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="507" mass="54572" checksum="8033CB7AA59DA63B" modified="2011-01-11" version="1">MQLSVLWRAPEVNPINRKARSIPVFNIFNIYARAFHFSWLGFMIAFWAWYTFPPLLTVTIKKDLKLNNAQVANSNIVSLVATLFMRLIAGPACDRFGSRIVFGSLLLIGTLPVGLAPLVTNVTGLYISRFFIGVLGATFVPCQVWCTGFFDKNVVGTANALAGGWGNGGGGLSYWVMPAVFDSFVHARGYSPGQAWRMTFIVPVICLLACGLGLLLLCKDTPTGKWADRHLHAQENLRSHGVNAVIDVPGGIADRTIGSMASDEEKSSTHGKNGVIAKNDAPLSGAEMIETAQGDTVVNPTFKDAMKVVLSPQTLFHVATYGCSFGGELAINSILSSYYLKNFPSLGQTGASNWAAMFGFLNIITRPAGGVVSDLLYRFGGHSLWLKKGWITVCGILTGALLILIGQLNPHNEATMFGLVFLMAIFLEAGNGANFGLIPHVHSHANGIVSGLTGAGGNFGGVVFAIIFRFMDHGANYAKGLWVIGCIHIAVYIGVSWIHPLPKNQRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6G5</accession>
    <name>E3Q6G5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA polymerase II holoenzyme cyclin-like subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_01557</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclin family. Cyclin C subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090433.1">
        <property type="nucleotide sequence ID" value="XM_008092242.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6G5"/>
    <dbReference type="STRING" id="645133.E3Q6G5"/>
    <dbReference type="GeneID" id="24406922"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01557"/>
    <dbReference type="eggNOG" id="KOG0834">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022000_7_1_1"/>
    <dbReference type="OrthoDB" id="25002at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20546">
        <property type="entry name" value="CYCLIN_SpCG1C_ScCTK2-like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000072">
        <property type="entry name" value="Cyclin Pch1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043198">
        <property type="entry name" value="Cyclin/Ssn8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10026">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0195">Cyclin</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="6">
        <location>
            <begin position="113"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="323"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="25"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="406"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ26413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="434" mass="49140" checksum="052111C7A0963498" modified="2011-01-11" version="1">MASIDRYRPSKEAYQPPNLPPGPPRPDRLSRSPARRLDVPPAVPSPPTHSSRTSPPRPLSQRDTRSPQRSRAQTPGPPPNQWYFTADETLSTPSVLDGISPVEERLRRAKGINFIYQAGVLLDLPQITLWVAGVFFHRFYMRYSMVEEKGGIHHYNIAATALFLANKTEENCRKTKEIIITVAKVAQKNPKLMIDEMSKEYWRWRDSILMYEELMLEYLTFDLMVENPYQRLFELLGQLDIVHNKHLRQSAWAFCSDACLTSIPLLLEARDVAITAIFFASVHTNQKIDDVNGEPWWKALKGNEEKCAKAIDIVRQFYTENPLRKQNPSLPSPAFDLANTRQPRDPMSQDALSSTAGTPFELDRGTQSPKARVNGRDDVTNTESGSQATLKEPERPNGNGATSPGKRKEVDSDTEGRDQKRARLSDEDEGEVLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6N2</accession>
    <name>E3Q6N2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Emp24/gp25L/p24 family/GOLD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_01624</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endomembrane system</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 8">Membrane</location>
            <topology evidence="1 8">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the EMP24/GP25L family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090500.1">
        <property type="nucleotide sequence ID" value="XM_008092309.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6N2"/>
    <dbReference type="STRING" id="645133.E3Q6N2"/>
    <dbReference type="GeneID" id="24406989"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01624"/>
    <dbReference type="eggNOG" id="KOG1692">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066963_4_0_1"/>
    <dbReference type="OrthoDB" id="62956at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006621">
        <property type="term" value="P:protein retention in ER lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016050">
        <property type="term" value="P:vesicle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015720">
        <property type="entry name" value="Emp24-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009038">
        <property type="entry name" value="GOLD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036598">
        <property type="entry name" value="GOLD_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22811">
        <property type="entry name" value="TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01105">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01190">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101576">
        <property type="entry name" value="Supernatant protein factor (SPF), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50866">
        <property type="entry name" value="GOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178244" evidence="9">
        <location>
            <begin position="22"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="GOLD" evidence="10">
        <location>
            <begin position="31"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ26480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="203" mass="23294" checksum="56A3AD9720F9D0F9" modified="2011-01-11" version="1">MFFPSVAKLLLAAGFAHSALAHNIALPAHGRECFHETLHRDDKMTVTFQVGDREFGSAGNLDIDFWITNPQGQYETFDKSVSNGDFSFDAKHDGKYTYCFGNEHWGAHSKEVSFNVHGIVYVSETDVPADPLETEVRHLSELLAQVKDEQSYIVIRERTHRNTAESTNSRVKWWNLFVIGLVIGESVFQVWWLRRFFEVKRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6Q0</accession>
    <name>E3Q6Q0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pre-rRNA processing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_01642</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090518.1">
        <property type="nucleotide sequence ID" value="XM_008092327.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6Q0"/>
    <dbReference type="STRING" id="645133.E3Q6Q0"/>
    <dbReference type="GeneID" id="24407007"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01642"/>
    <dbReference type="eggNOG" id="ENOG502S22Q">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035244_1_1_1"/>
    <dbReference type="OrthoDB" id="10039566at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022185">
        <property type="entry name" value="DUF3712"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046368">
        <property type="entry name" value="Tag1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35895">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35895:SF1">
        <property type="entry name" value="LIPID-BINDING SERUM GLYCOPROTEIN C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12505">
        <property type="entry name" value="DUF3712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="34"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ26498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="343" mass="37238" checksum="5787DB1F026E44F2" modified="2011-01-11" version="1">MNKREISHTESVAGGSDSSGGGKRKTCMRHCARFWWIYLIGIIAAILLIVLLIIFVAVPKIAQSKLDHVELTVDGIIVSNTRSNSYNMAINSTLRSDGSVKATVEPFDGVMYLEDLEPHTPFVNLKFPETKSVKLQTVNISQPIEIADMAAFTTFNTWLQNNESVRVTVKGNTHIKVNGIARRYGAVFRNTMTLKGLNGFKGLNVTESSISLTPDARGNNFKGHVSIPNHSVLTLEIGNATFSNLLDGQDIGTVYIDNLVLYPGVNNVTMRASISQAPVLAAIGKRPACETGIVPFALRGKDVENDGQKLSYFADALASDQVITDINIGAALKQSLNISMSCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6Q9</accession>
    <name>E3Q6Q9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_01651</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090527.1">
        <property type="nucleotide sequence ID" value="XM_008092336.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6Q9"/>
    <dbReference type="GeneID" id="24407016"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01651"/>
    <dbReference type="eggNOG" id="ENOG502SA5Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095023_1_0_1"/>
    <dbReference type="OrthoDB" id="2151417at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38849">
        <property type="entry name" value="SMALL SECRETED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38849:SF1">
        <property type="entry name" value="SMALL SECRETED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180164" description="Small secreted protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ26507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="174" mass="17980" checksum="91C0206F1F0986C5" modified="2011-01-11" version="1">MYFSKIAVLFALAATGLSAPVEAVDKRQANLLTVQNYSQFQVSDGVGGNALGEVAQKFPIAQLKANLKGVSKNDLAILQGARVAAESAETDAGGFNDAIAKASGADAAALTVGKIKNKVLKLQLEVLALQVQQAQGANNQAKIDAEQKKLDNNVQLDKAAAGKPSKSVAFNATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7D6</accession>
    <name>E3Q7D6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">V-type proton ATPase proteolipid subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_02594</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Proton-conducting pore forming subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11 12">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Vacuole membrane</location>
            <topology evidence="1 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the V-ATPase proteolipid subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090794.1">
        <property type="nucleotide sequence ID" value="XM_008092603.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7D6"/>
    <dbReference type="STRING" id="645133.E3Q7D6"/>
    <dbReference type="GeneID" id="24407959"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02594"/>
    <dbReference type="eggNOG" id="KOG0232">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085752_1_1_1"/>
    <dbReference type="OrthoDB" id="1744869at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000220">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18175">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6C_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18176">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6C_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.610:FF:000003">
        <property type="entry name" value="V-type proton ATPase proteolipid subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.610">
        <property type="entry name" value="lithium bound rotor ring of v- atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000245">
        <property type="entry name" value="ATPase_proteolipid_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011555">
        <property type="entry name" value="ATPase_proteolipid_su_C_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01100">
        <property type="entry name" value="V_ATP_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10263">
        <property type="entry name" value="V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00122">
        <property type="entry name" value="VACATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="F1F0 ATP synthase subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <keyword evidence="4 12" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="97"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="133"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="13">
        <location>
            <begin position="19"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="13">
        <location>
            <begin position="99"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00045519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00046480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ26774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="164" mass="16782" checksum="2F47F0924A051FE9" modified="2011-01-11" version="1">MAEDSVLAPKFAPFIGMAGIAAAMIFGCIGAAYGTAKSGIGIAGVGTFRPDLIMKCLIPVVMSGIIAVYSLVISVLIAQDLTPPGAGSNYSLFNGFMHLACGLSVGLTGLAAGYTIGIVGDKGVRSYMEQSRIFVGMVLILIFGEVLGLYGLIVALILNTKSKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7M7</accession>
    <name>E3Q7M7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Chromosome segregation in meiosis protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_02685</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Plays an important role in the control of DNA replication and the maintenance of replication fork stability.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the CSM3 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090885.1">
        <property type="nucleotide sequence ID" value="XM_008092694.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7M7"/>
    <dbReference type="STRING" id="645133.E3Q7M7"/>
    <dbReference type="GeneID" id="24408050"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02685"/>
    <dbReference type="eggNOG" id="KOG3004">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036204_1_0_1"/>
    <dbReference type="OrthoDB" id="437078at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031298">
        <property type="term" value="C:replication fork protection complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000076">
        <property type="term" value="P:DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043111">
        <property type="term" value="P:replication fork arrest"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012923">
        <property type="entry name" value="Csm3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040038">
        <property type="entry name" value="TIPIN/Csm3/Swi3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13220">
        <property type="entry name" value="TIMELESS INTERACTING-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13220:SF11">
        <property type="entry name" value="TIMELESS-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07962">
        <property type="entry name" value="Swi3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0236">DNA replication inhibitor</keyword>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromosome segregation in meiosis protein 3" evidence="9">
        <location>
            <begin position="64"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="145"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="145"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="210"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="231"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ26865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="275" mass="31067" checksum="5DEB6CEDF8D76A36" modified="2011-01-11" version="1">MDPKTSLHHDDLDNYNVDDFDDPFQSPPPEVRDGNSRNKRKKAEALGLDEEVEVAKRVRVPRVKLDETRLLSENGIPKLRKRATNLRFKGRGHEFSDAARLLAFYQLWLDDLFPKAKFLDALAMVEKAGHKKQIALKRMDWINEGKPKPWEEDDDKMEKGNESTGQKKDMTPLAPAVTMGTEEQRPITPEGGYMPDDHDIYGATPLVPVGRREQERSKRPIEEPEDDDLDALMAEAEAASQAQAQAQSRQAPGVKSVTDDFADEEAAMAEMDGLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7Q5</accession>
    <name>E3Q7Q5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_02088</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ26917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090937.1">
        <property type="nucleotide sequence ID" value="XM_008092746.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7Q5"/>
    <dbReference type="GeneID" id="24407453"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02088"/>
    <dbReference type="eggNOG" id="ENOG502SS80">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059970_0_0_1"/>
    <dbReference type="OrthoDB" id="2906425at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF15">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ26917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="403" mass="44992" checksum="9C8EEAA8D82EB8AA" modified="2011-01-11" version="1">MSATAPDCLVPDLTILSGISELDGITMCKYRIISNSSTTCTAVASLEEDQSPCGLPTHLIIRLEKSRDGNPLFATAAFQRLAHRRLPHLVPKVWGAGHTQTEKGAKISYMLSQYYMDTCTLESVWDDMDKFSRHALVEQVVSNLVHLKDVSVANVNDETEILRGTPFERTKTGNSAMVGGPAYGYFRDFSSFLMSTLSSGSKRYSIDRKPDGTLAIQMKSPQETGFGFAQTDLDLLLHMSVLCHNNLEPRNILVRKVITSNNRVTCQLVSVIGWEMAGFFPFAFEVGYKDTCLGLQNQSWSWYSWYRLSAGRILSGTAPAARPICFKLIQSMVLTDIAKKEANKLNVGNLVQKLWHEREQTMAYVDAETGYAKNPNIVGVNSFNMTDNAELELEALRKLRYID</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q884</accession>
    <name>E3Q884_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">BTB/POZ domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02267</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091116.1">
        <property type="nucleotide sequence ID" value="XM_008092925.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q884"/>
    <dbReference type="STRING" id="645133.E3Q884"/>
    <dbReference type="GeneID" id="24407632"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02267"/>
    <dbReference type="eggNOG" id="ENOG502SMAU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_844703_0_0_1"/>
    <dbReference type="OrthoDB" id="5275938at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="52"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="328" mass="36581" checksum="E7B8CA37620D0F47" modified="2011-01-11" version="1">MEHPLDKHMAIDKPAAAAAEAPERFFEVQSPASFAARMWARKYSGVPVVPDGDVILVVGVGEETAELRADSVILRRASRVFGAMLGPRFSEGQKLLDRGSDPVKISLPDEDPEVMELVLTILHHQNARVCQIAAADSILEVAVIADKYDLVDALKYASQTMLRYHEPSIDRLTVGDLWRLGLAAGLLNEARSFEKITRMLVWNHTMPYIQLADAEDVIDIEFALRMCYLLEKERQDLKASLLLHLLPIISTGSQLRLVEIKVDSAEHFDAWPELMKLFGASLQETTKFAEGLVLADSRRRAAGPGSDFMRHFKARGGIRLADVRRGRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8Y8</accession>
    <name>E3Q8Y8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_01997</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091522.1">
        <property type="nucleotide sequence ID" value="XM_008093331.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8Y8"/>
    <dbReference type="STRING" id="645133.E3Q8Y8"/>
    <dbReference type="GeneID" id="24407362"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01997"/>
    <dbReference type="eggNOG" id="KOG0504">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_745980_0_0_1"/>
    <dbReference type="OrthoDB" id="539213at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902495">
        <property type="term" value="C:transmembrane transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034220">
        <property type="term" value="P:monoatomic ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052076">
        <property type="entry name" value="TRP_cation_channel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47143:SF1">
        <property type="entry name" value="ION_TRANS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47143">
        <property type="entry name" value="TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 8" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="9" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="90"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="8">
        <location>
            <begin position="256"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="8">
        <location>
            <begin position="321"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ27502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="371" mass="41088" checksum="A77A5854BC375F5B" modified="2011-01-11" version="1">MVDRLVSCGIFLRASLYQKRGIEIREQLSQPGYDLEFSFAEKAVMKERLADILLRSETEEETVEAKTILQRLLEEEVKQPDEFKNVERRSRLYHNLGCLYINLGNLKQAKTFLSRALEGRKNQKPMPVQSVQETADLYIKALKLDGAFDEAGGVEVWLNNVIIPLASRPASPPDSDLIGGLRRPSSMGELSQAFAWCRENGFDIDMPGGFRFDTCDFMTRTSPLHKAIQDENVDVLKQMVGHVVSLETGGDLGVPTPLLLAASTKNRDIVGLLLRRGARVNVRDSAGLSPLHRCQSKSGGVNVAKLLLDDTPTLLDAVDNSGKTALFMACEMGNEKMVHFLLEQGANPNICQKTRRGPTLSPYLGGTNEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q962</accession>
    <name>E3Q962_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_01736</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091261.1">
        <property type="nucleotide sequence ID" value="XM_008093070.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q962"/>
    <dbReference type="STRING" id="645133.E3Q962"/>
    <dbReference type="GeneID" id="24407101"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01736"/>
    <dbReference type="eggNOG" id="KOG1591">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058132_0_0_1"/>
    <dbReference type="OrthoDB" id="420380at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF246">
        <property type="entry name" value="TRANSMEMBRANE PROLYL 4-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180239" evidence="6">
        <location>
            <begin position="22"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="Prolyl 4-hydroxylase alpha subunit" evidence="7">
        <location>
            <begin position="44"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ27241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="252" mass="28030" checksum="B79B54D09CA1ABB8" modified="2011-01-11" version="1">MRLSLFAAVFAFGAAAYGSSSDDDLDDYVCEHSNYKIHLFSHSPLVIYINDFVTPFESRHLQKITNGTFARSNVSSHEGDIVSSHRTSHSTTVTPDAVTQCIQERARQFQGLDMPQTYLEPIQLVKYGLGQQYHSHMDWFPGDLGQHRSVAEGGNRVSSFFTYIKASDDIVGGGTNFPRLRAPAGKQWCKVVACDEPWEAGVTFRPVEGNAIFWTNLLDGGEGDERVLHAGLPVERGVKLGMNIWTRQGPFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9E6</accession>
    <name>E3Q9E6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tautomerase cis-CaaD-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_01820</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091345.1">
        <property type="nucleotide sequence ID" value="XM_008093154.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9E6"/>
    <dbReference type="GeneID" id="24407185"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01820"/>
    <dbReference type="eggNOG" id="ENOG502SRX7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_088298_1_0_1"/>
    <dbReference type="OrthoDB" id="9981319at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.429.10">
        <property type="entry name" value="Macrophage Migration Inhibitory Factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028116">
        <property type="entry name" value="Cis-CaaD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014347">
        <property type="entry name" value="Tautomerase/MIF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14832">
        <property type="entry name" value="Tautomerase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tautomerase cis-CaaD-like" evidence="1">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="179" mass="20382" checksum="F3F296CE90C144AD" modified="2011-01-11" version="1">MPFYQTYHTYPLSQTQRQSFALSITNLHCSAFNTPAFFVHVSFSDQSSKPDDGTYFMAGKPHSTNCNRILAVVRTSASRTKADFDRLAASIEDAWNGALEEPDAEHTKGYKEPDECKRLLMIMFTPMLAIREGGMAIPEAGHEDDWLAQQLPYIKTMAEKHNVDDFRELLEEVEQRQSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9H6</accession>
    <name>E3Q9H6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GPI anchored protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_01850</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091375.1">
        <property type="nucleotide sequence ID" value="XM_008093184.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9H6"/>
    <dbReference type="STRING" id="645133.E3Q9H6"/>
    <dbReference type="GeneID" id="24407215"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01850"/>
    <dbReference type="eggNOG" id="ENOG502SR6P">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101050_2_0_1"/>
    <dbReference type="OrthoDB" id="5362269at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179552" description="GPI anchored protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ27355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="181" mass="18356" checksum="B4571435AC06F8E3" modified="2011-01-11" version="1">MKTSQILAAFCFAALSMAQSESLAPSPTESWGCEPHGDHWHCEGARSTVTIKSTSISTSRSLFIPSASGTVTKDHDHDHDDDDDDHSSGTGSYTLAPSPTESFGCEAHNDHWHCEGPVTAASRSATTTIEATLTPSATTDGAATTATGEGADATATALPAGAARAGFGAAAVAAAVAFIAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9I0</accession>
    <name>E3Q9I0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_01854</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091379.1">
        <property type="nucleotide sequence ID" value="XM_008093188.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9I0"/>
    <dbReference type="GeneID" id="24407219"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01854"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_5_1"/>
    <dbReference type="OrthoDB" id="1932925at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF55">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G01820)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="74"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="252"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="318"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="354"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="383"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="413"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="445"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="477"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ27359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="536" mass="57463" checksum="18C37E4414CAD7BC" modified="2011-01-11" version="1">MAPEKDLVATPGDPAPGPPPTSGPDPDVEATATSTSGPGKNGDDDDDALAMVGAHAQPYDPAVAARAVRQIDRFLVPAMVFGYGLVYYDKAILGSAVLFGMTADLRLSVPVPGGGVDTSRLSWATSLFYFGMLAGLYPMTYALQRFPPGRTLGAVVLAWAAACASTAAVSDHRGLYAQRFALGFVESAVPTGFMCVVAGYYTQAEQSLRQSWWFSATGLFTIIGGGLNYAFAQVPSSSARGNGGRLRPWQSIYILAGCLTFLFGVACFFLPASPVSAWFLTPEERFAAVERLRRGQTGVRCAKFKPHQLREAVADAKVWLVALMMASAYTMNGAVSGFGPLIVSTFGWSPLQAILLQFPLGAVCFAVILLTGYLGSRLPNARVVMLVACCLPVIAGCALVWRADWSRRAAAPVVGYSLTGFFGGVVSLVISLGMSNVAGHTKKSFVAATVFVAYCVGNIVGPQLVRSQSRARHYPELWTGLIVCYVICVLAAAALYRLLRAENRRRDALPVDEEERAKLAFQDLTDKENPYFRYVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9K1</accession>
    <name>E3Q9K1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C6 zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_01875</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091400.1">
        <property type="nucleotide sequence ID" value="XM_008093209.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9K1"/>
    <dbReference type="STRING" id="645133.E3Q9K1"/>
    <dbReference type="GeneID" id="24407240"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01875"/>
    <dbReference type="eggNOG" id="ENOG502S495">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015886_0_0_1"/>
    <dbReference type="OrthoDB" id="5206661at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="426"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="508"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="524"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="549"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="559" mass="60925" checksum="F80AD0580F44F2C5" modified="2011-01-11" version="1">MSNSRGLPDVLMTKVDEYVDSLAPQIQPRIAAEIDTFQTRTIDSLEDQVIDAFRSLFNKDKPSGDGSRGLNDAPPDAYGVQSLPFADEIGKLTRSFSVITDEAGDDLRDIFNLTEGGGGGPETQSRGVSHTDSFSGARGFLSSAINVVQDHLDKNKGPGGQGFELDGLLGVLSNTVKDAARNPEEKARAISPEIKEKVGLKLKEQHAPIAEQFTRIALDHIKRWLRGNTSTRDLGDGVKGEIEDQVKDLVKGLGGLFGNKKSSQEAGARGFGDRDGEGEGSSGGGGFSRVISDKLSTGLAKVHRDVRLEFRKIFGGIEKQLFELLPDSFQRPLEKILGGNPFDAQLDRDAGGHADRGFGDDIKVKLVNKIRGLVRKVQETLRESILGVVNGGHRRFERESWVFVQNMVEQKVQKYLPKVKIHVPDDIGNENVSVGAPTAGSQLGSAGGHPSGPPQGSNYAPPPPQQHDQYGGQGSHQQPYNPPSHQEYRPDQHQQYQSHQEYRPSGDQPPQSYQQYHSEQQQGYGHGQGQSYGGNQNYGGGQNYGGNPDHNQYGENPRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9T5</accession>
    <name>E3Q9T5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_02767</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091643.1">
        <property type="nucleotide sequence ID" value="XM_008093452.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9T5"/>
    <dbReference type="STRING" id="645133.E3Q9T5"/>
    <dbReference type="GeneID" id="24408132"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02767"/>
    <dbReference type="eggNOG" id="ENOG502SDW6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_190851_0_0_1"/>
    <dbReference type="OrthoDB" id="2555959at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ27623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="63" mass="7015" checksum="5939E4D11677B2BC" modified="2011-01-11" version="1">MFKAYKNLSPKTRLSVGVAVLAWGAAGLYLSDQAEEKYQPTPEEKAIVDKYVPKVTVVDRSKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QA42</accession>
    <name>E3QA42_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_02874</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IST1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091750.1">
        <property type="nucleotide sequence ID" value="XM_008093559.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QA42"/>
    <dbReference type="STRING" id="645133.E3QA42"/>
    <dbReference type="GeneID" id="24408239"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02874"/>
    <dbReference type="eggNOG" id="KOG2027">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037652_2_1_1"/>
    <dbReference type="OrthoDB" id="29853at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042030">
        <property type="term" value="F:ATPase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099638">
        <property type="term" value="P:endosome to plasma membrane protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032511">
        <property type="term" value="P:late endosome to vacuole transport via multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1260.60:FF:000002">
        <property type="entry name" value="Vacuolar protein sorting-associated protein IST1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.60">
        <property type="entry name" value="Vacuolar protein sorting-associated protein Ist1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005061">
        <property type="entry name" value="Ist1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042277">
        <property type="entry name" value="IST1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12161">
        <property type="entry name" value="IST1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12161:SF5">
        <property type="entry name" value="IST1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03398">
        <property type="entry name" value="Ist1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="175"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="183"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="232"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ27730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="295" mass="32724" checksum="3369A46C3569EB8C" modified="2011-01-11" version="1">MAPPPTITTKLKVQLKLAIARLRMVQQRDDSMSKTQRRAMAQLLEVGKIDSARIRVENIIRSDITTELHEILELYCELLIARAGLLEGSTCDPGLEEAVKSIIYAAPKTEIKELQVVRTLLGEKYGKEFVLSAMENSDGKVSEKVIKKLSVTPPREELVQGYLEEIAKAYNVDWPRRPRAEEQPDLLDDDDEDSPSGGIGMRIPEGNSSKLAQEQEELSKATPPRTIGVPSSPLTVTPPRMTTDNIHPKVTLNSLELKPNKKMDAAVQKKPNSQGPGGSVPDITELERRFAALKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBD9</accession>
    <name>E3QBD9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_03422</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. BUD32 family.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092298.1">
        <property type="nucleotide sequence ID" value="XM_008094107.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBD9"/>
    <dbReference type="STRING" id="645133.E3QBD9"/>
    <dbReference type="GeneID" id="24408787"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03422"/>
    <dbReference type="eggNOG" id="KOG3087">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1759905_0_0_1"/>
    <dbReference type="OrthoDB" id="3399at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000408">
        <property type="term" value="C:EKC/KEOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070525">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000603">
        <property type="entry name" value="EKC/KEOPS complex subunit bud32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12209:SF0">
        <property type="entry name" value="EKC_KEOPS COMPLEX SUBUNIT TP53RK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12209">
        <property type="entry name" value="NON-SPECIFIC SERINE/THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ28278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="148" mass="16267" checksum="B4A89361295BF192" modified="2011-01-11" version="1">MASPPEGAFPLPPILALPSSPAGAPVLVTQGAEARLYRTTFLAPRLPAALKYRPKKPWRHPTLDARLTRARILAEARVLAKCRREGCPVPALYALDEVAGWLMLEWIPGAPVRVRINEWLDGVVADVLEDEARDGGSRADYRARRPDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBW8</accession>
    <name>E3QBW8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">5-hydroxyisourate hydrolase</fullName>
            <shortName evidence="7">HIU hydrolase</shortName>
            <shortName evidence="7">HIUHase</shortName>
            <ecNumber evidence="7">3.5.2.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_03347</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>5-hydroxyisourate + H2O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23736"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18072"/>
            <dbReference type="ChEBI" id="CHEBI:58639"/>
            <dbReference type="EC" id="3.5.2.17"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4 7">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.17" evidence="7"/>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092223.1">
        <property type="nucleotide sequence ID" value="XM_008094032.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBW8"/>
    <dbReference type="STRING" id="645133.E3QBW8"/>
    <dbReference type="GeneID" id="24408712"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03347"/>
    <dbReference type="eggNOG" id="KOG3006">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115536_0_1_1"/>
    <dbReference type="OrthoDB" id="10265230at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033971">
        <property type="term" value="F:hydroxyisourate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006144">
        <property type="term" value="P:purine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05822">
        <property type="entry name" value="TLP_HIUase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.180">
        <property type="entry name" value="Transthyretin/hydroxyisourate hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014306">
        <property type="entry name" value="Hydroxyisourate_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023418">
        <property type="entry name" value="Thyroxine_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023416">
        <property type="entry name" value="Transthyretin/HIU_hydrolase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036817">
        <property type="entry name" value="Transthyretin/HIU_hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023419">
        <property type="entry name" value="Transthyretin_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02962">
        <property type="entry name" value="hdxy_isourate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10395:SF7">
        <property type="entry name" value="5-HYDROXYISOURATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10395">
        <property type="entry name" value="URICASE AND TRANSTHYRETIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00576">
        <property type="entry name" value="Transthyretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49472">
        <property type="entry name" value="Transthyretin (synonym: prealbumin)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00768">
        <property type="entry name" value="TRANSTHYRETIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00769">
        <property type="entry name" value="TRANSTHYRETIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transthyretin/hydroxyisourate hydrolase" evidence="9">
        <location>
            <begin position="9"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="31"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ28203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="141" mass="15376" checksum="296F6B5499E87228" modified="2011-01-11" version="1">MASQTKDRITCHVLDTSAGRPARGVRVHLSTTVPSSSPSTTGGVLREFESQTDDDGRVKAWLPFSDATASGEVPVYTLEDVLGALQGPSRWTLRFDTAAYFGGEDATFFPEAVVVFTVREGQHYHVPLLLSPYSYTTYRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>E3QD32</accession>
    <name>E3QD32_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Crossover junction endonuclease MUS81</fullName>
            <ecNumber evidence="14">3.1.22.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">GLRG_03948</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="14">Interacts with EME1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 14">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the XPF family.</text>
    </comment>
    <dbReference type="EC" id="3.1.22.-" evidence="14"/>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092824.1">
        <property type="nucleotide sequence ID" value="XM_008094633.1"/>
    </dbReference>
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    <keyword evidence="8 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 14" id="KW-0460">Magnesium</keyword>
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    <keyword evidence="5 14" id="KW-0479">Metal-binding</keyword>
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    <keyword evidence="12 14" id="KW-0539">Nucleus</keyword>
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        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
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    </evidence>
    <sequence length="588" mass="66190" checksum="F63CE0E149247AC5" modified="2011-01-11" version="1">MAGEHEQYANPLLLDWVKEWLDTARERNMKSASTYRNAYESLKACPITFKHPRQLTQLKGFGDKLSSRLTDKLKEHCEANGLPMPTNPRLSKESRQLLGGAAEDDEPPPPKKTRKAKPYVPTYRSGPYALLLALSALDEEAQLGMTKANLIELAQEHCDSSFSAPSDPTKFYTAWNSMKTLIDKDLVCEKGRPQRRYSLTEEGWEVARRIKKTTESSSRADASVAGPSTRPELETRPDAATAALGRSASLSVEPVEQAKPKSVYEGVVANGPTVSDDASLPTFTPIRLAPGSFTVHLALDIREVRAVKDRDYMQDELTKKGVKPLMRALEIGDAQWIAKCHDSTALSRHGAEGDEVVLDWIVERKRLDDLVSSIKDGRFHEQKFRLRKSGVKHVVYIVEEISMDSGYYSKIEEMIQSATASTQVVNGYFLKKTQKMDDTIRYLARMTFMLKKMYENKPLHVIPTPALTAQNYLPLLEHLREKEPLTGYYITYPAFASLASKSDMMTLRDVFLKMLMTTRGITGEKALEIQKRWKTPHDFIKAYQECGSGEQGLKRKREMVINGLPNLVGRKKIAKAVSQRLAEVWGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDC2</accession>
    <name>E3QDC2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04038</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EFQ28894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_008094723.1"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="296767at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013887">
        <property type="entry name" value="UPF0592"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37988">
        <property type="entry name" value="UPF0592 MEMBRANE PROTEIN C7D4.03C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37988:SF1">
        <property type="entry name" value="UPF0592 MEMBRANE PROTEIN C7D4.03C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08578">
        <property type="entry name" value="DUF1765"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
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        <location>
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            <begin position="482"/>
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            <begin position="1208"/>
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            <begin position="101"/>
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            <begin position="173"/>
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            <begin position="323"/>
            <end position="343"/>
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            <begin position="344"/>
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    </feature>
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        <location>
            <begin position="490"/>
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    </feature>
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            <begin position="1054"/>
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    </feature>
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            <begin position="1208"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1230"/>
            <end position="1257"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ28894.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1333" mass="147069" checksum="344EBF19EFECD332" modified="2011-01-11" version="1">MAPAVVDSANGPYLHRSHPSDDRPDTAPVGATSTTTTRQRGPGVQDRAAFDLPSFNTIPEFDTTLYLDGKGSEEAAAKEKLPPVLSVTPAQSDQVKLAVPSRDDDKENTREGKQKEKDDEKLQKRGRRASLMERRKSWLPSSRSPSKVKEPPMPERPAMSERPSTHAGEHVGPAVPSAAPVAPARPVEPERPRTVSETFATFAKKSWMSTSRSPSPKRNLQPPAAPPPRPSRSRASSSDSVKGAEAPRKRPLSMLIYQESAAAKSAESLKPARALNRTSTFLTKIKQRPKSMLITFGSSLDSDANSVPASTNVLPPPSAAPEHGQRGRKDADSTVHTNKKSESKPASVTESHTTATDESWSEMSVIKDTIWSAFKTLDTEYGGFHSKTMAQRMHLVRATLLPFLRTYMNHPTNKGLNLEDVERRAIVLNKWWTGLLEMLDSQTQQLAGVDRPVLLEALTILMMRPEWRQTTTYFMSLADRSPNECVRPRSGTQSTTDSSQASSQAFLAESAEHNVRTMFVGNLMKQMQIVVDKMSLRHAPLSLVNWCGKACAYGFFFCPSVAEILVRLWDLRPELIRRTAEEFGLPKKNGGESEDIMALFPPNIGVLGWQSQKFISARFKERVKLSVMAARIPWFSPWVTRWRGGDTDLFFIFCKYYHILSEEFMPEGLPLLEKARSPGFVLVQAQILACIESTIHRQAEVDAMMNPLPPADSFYGADAAATSMTVPANLLKNMAENRLIVLLKDILGESLPVIAPARRTFAEAFLAVTRAATRRVSAFDHSAVFTLCDFLEEALVAYDQLDDLENPNIAQSMNWPFWLDVCRKMLVSDNAMTEVRLLSFIFSTWEAVTANPERKKALCLDWLLSEETFDAYFNHWCPMVRAYYMRLLCWRICRDAGSANEVDAQIFLVAAARLKTGWAHYLYLRNAANAAGKLPPSTSPCLPTPGKKFMIIRTEINLPQPGYFNQPFDSFSKIINGEGVMAASTPPPETKEVVTAKADNSKKRWSLIGKVLSLGGNSSDSEDNSEVSRKEAPLKPSALSKRRQGGPPLPPKISTSTASAATTSSDGSSPGASPIFMEQKFVFKFTLTWQPPAVTQPRDRLLTRPRLPAPAQAWVSARSRSGSSPPPLPAGLPDPTRRVSGSKKKGLVDGAKNASPLTSPTLERKSSVTAVSSSSLARRLSNKFDFENNPNVELMTFDFEGAEKSSASSMSSASSTASSPAEKKAEDEQLQPQSSSPQVQLQAQPQALEQQQQQQHQQKPEGRRNGPEPLTQPLRPTGMYAKRAVYTGRALAEWSLIVAECNGFVDRRRDEGVLGLSEVEVPMLTVEGFRKIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDV5</accession>
    <name>E3QDV5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Guanine nucleotide-binding protein alpha-2 subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_04187</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the G-alpha family. G(q) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093063.1">
        <property type="nucleotide sequence ID" value="XM_008094872.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDV5"/>
    <dbReference type="STRING" id="645133.E3QDV5"/>
    <dbReference type="GeneID" id="24409552"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04187"/>
    <dbReference type="eggNOG" id="KOG0082">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014184_6_0_1"/>
    <dbReference type="OrthoDB" id="5817230at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090726">
        <property type="term" value="C:cortical dynamic polarity patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007186">
        <property type="term" value="P:G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0180040">
        <property type="term" value="P:negative regulation of pheromone response MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000750">
        <property type="term" value="P:pheromone-dependent signal transduction involved in conjugation with cellular fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00066">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.400.10:FF:000009">
        <property type="entry name" value="Guanine nucleotide-binding protein G(O) subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000051">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000692">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.400.10">
        <property type="entry name" value="GI Alpha 1, domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002975">
        <property type="entry name" value="Fungi_Gprotein_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF242">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-1 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00318">
        <property type="entry name" value="GPROTEINA"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01241">
        <property type="entry name" value="GPROTEINAFNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0807">Transducer</keyword>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="43"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="187"/>
            <end position="193"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="212"/>
            <end position="216"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="281"/>
            <end position="284"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="339"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00074402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ29043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="366" mass="42138" checksum="2BA4B2B7C7600108" modified="2011-01-11" version="1">MCFGARKSDDGGAVRSRDLDRLIRQDEKRLAKEVKLLLLGAGESGKSTVLKQMKLIYAQGFSKNEKLEWKPVVFNNIVQSFRLIQDAMTEMGIDFSNPENEASSPSPWHGQSHKHMAHILVEHEINAQDPLPRDYLQPIKELWVDEGVKQAIAKGNEFALHDNLAYFCDDLDRIWDQAYVPTDQDLLRSRLRTTGITETVFDLGQLTYRMFDVGGQRSERKKWIHCFENVNCLLFLVAISGYDQCLVEDKDGNQMNEALMLWESIANSHWFTKSALILFLNKMDLFKEKLTNNPITSHGFTDYHGPPDDWKAASKYFLDKFRALNRNTEKEIYGHFTNATDTNLLKITMGSVQDMIIQRNLKQLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDY1</accession>
    <name>E3QDY1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Polyamine transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_04213</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093089.1">
        <property type="nucleotide sequence ID" value="XM_008094898.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDY1"/>
    <dbReference type="STRING" id="645133.E3QDY1"/>
    <dbReference type="GeneID" id="24409578"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04213"/>
    <dbReference type="eggNOG" id="ENOG502RYRH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002903_1_0_1"/>
    <dbReference type="OrthoDB" id="10250282at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF186">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="48"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="160"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="244"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="276"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="333"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="366"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="507"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="529"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="563"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ29069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="577" mass="63641" checksum="1E761186D0A77883" modified="2011-01-11" version="1">MGVCLGFASMNFHSILTDLFGASLMSSNPHQEVVDDFDVRRHGGGMGVWLGIWTWCYIASLGFGFLIGAAVIDQLQPAWGFYISIILVAVVLLLNTLCPEVRRSAFRRSVVEVRTGSDITRRVARGEIMMHRVKTGPRWWGQELYHGVALCFEMLRQPGFVVIAVYSGWIYAQVVLVIVLLGSLSSRFYRMRSPYVGLMVAAMAFGAVIAIPFQKASYFSRARHTQVNTSRLTFDKQITWTSHLLRRSVFAIGLPLAGLVYTLVSTGPPMHPSAPAIVAAAIGFLSCLAISECNGLIMETFDTSDLQPGMMGRLPGNSDIARKKKNYSAYPRVTAGFAVCHTLGFMFAAGATALGGMAQRNLGQRAATGVVAGILFVFTVMLLLALARFKEVVIIPESKTEEMDKWTAARRQSIRRRDSLPAGTVDDKDIIAGEEPWRPFIVGNPTSKTRRVNVLELGSMSRFTEIRKRNKLIDDNQHLNRAALDAGLDALDDQISDIMSDIVSDAKDLVGGNSQPSQRTSRSRRNHRSATSEGSGHSSIEMTSMDDRPSLSGHRQRAPPDIYNKRECLRGQMVKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEE2</accession>
    <name>E3QEE2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9 11">Alpha-glucuronidase</fullName>
            <ecNumber evidence="2 9 11">3.2.1.139</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">aguA</name>
        <name evidence="16" type="ORF">GLRG_04392</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Alpha-glucuronidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose. Releases 4-O-methylglucuronic acid from xylan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9 11">
            <text>an alpha-D-glucuronoside + H2O = D-glucuronate + an alcohol</text>
            <dbReference type="Rhea" id="RHEA:20005"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:58720"/>
            <dbReference type="ChEBI" id="CHEBI:58899"/>
            <dbReference type="EC" id="3.2.1.139"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9 11">Belongs to the glycosyl hydrolase 67 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.139" evidence="2 9 11"/>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093268.1">
        <property type="nucleotide sequence ID" value="XM_008095077.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEE2"/>
    <dbReference type="STRING" id="645133.E3QEE2"/>
    <dbReference type="GeneID" id="24409757"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04392"/>
    <dbReference type="eggNOG" id="ENOG502QWS4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007125_2_0_1"/>
    <dbReference type="OrthoDB" id="6501611at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046559">
        <property type="term" value="F:alpha-glucuronidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02795">
        <property type="entry name" value="CBM6-CBM35-CBM36_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1330.10">
        <property type="entry name" value="Alpha-glucuronidase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.379.10">
        <property type="entry name" value="Chitobiase/beta-hexosaminidase domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037054">
        <property type="entry name" value="A-glucoronidase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011395">
        <property type="entry name" value="Glyco_hydro_67_aGlcAse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005154">
        <property type="entry name" value="Glyco_hydro_67_aGlcAse_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011099">
        <property type="entry name" value="Glyco_hydro_67_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011100">
        <property type="entry name" value="Glyco_hydro_67_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029018">
        <property type="entry name" value="Hex-like_dom2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39207">
        <property type="entry name" value="ALPHA-GLUCURONIDASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39207:SF1">
        <property type="entry name" value="ALPHA-GLUCURONIDASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07477">
        <property type="entry name" value="Glyco_hydro_67C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07488">
        <property type="entry name" value="Glyco_hydro_67M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03648">
        <property type="entry name" value="Glyco_hydro_67N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029900">
        <property type="entry name" value="Alpha-glucuronds"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55545">
        <property type="entry name" value="beta-N-acetylhexosaminidase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6 9 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="3 9 11" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013356797" description="Alpha-glucuronidase" evidence="12">
        <location>
            <begin position="16"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha glucuronidase N-terminal" evidence="13">
        <location>
            <begin position="21"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 67 catalytic" evidence="15">
        <location>
            <begin position="144"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 67 C-terminal" evidence="14">
        <location>
            <begin position="476"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="303"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="386"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR029900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR029900-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF07477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF07488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EFQ29248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="846" mass="93283" checksum="6B91BAB86CA2A162" modified="2011-01-11" version="1">MWKLLLIASLGLVIAEDGLAGWLRYARLPDCKSAGVADSLPSTIVGLNATENGPISSALSELTKGYHGIFGKEVSLGEDACADSSVVVATLDDYIAACGSEGVEADLIEDGFWLSIKGGAVKILGQNERGTLYGAFEYLSLLAQGNFTETTYATNPSAPVRWANQWDNMDGTGTHGSIERGYGGVSIFFENLKVVTDMTRISQYGRLLASARINGIIVNNVNANPILLSPDNMDGLKRIADAFRPWGVQVGISLNFASPQTFGGLSTFDPLDDAVIAWWGRITDELYARIPDMAGYLVKANSEGQPGPLTYNRTLADGANLFARELKNHGSKRGIVMFRAFVYDHLTLNESDWHADRANAQVEFFKHLDGQFDDNVIVQIKYGAIDFQVREPVSPLFANLKETSMAIELQISQEYLGQQDHLVYLPPLWKTILDFDLRIDGQPSPVRDILSGKRLDRPLGGYAGVINVGANSTWLGSHLAMSNLYAYGRLAWNPTDDVVAIVQDWSRLTFGLNRKVVDTITSMSMESWPAYENYSGNLGIQTLTDILYAHYGPSPRSQDGNSWGQWTRADGNSIGMDRTVKNGTGNAGMYPPEVAAIYEEIETTPDDLLLWFHHVPYTHVLKSGKTVIQHFYDAHYEGSATTQTFVPQWESLQGLIDEERYEHVLFKLQYQAGHSLVWRDSINNFYWNMSGIPDEAGRVGNYKYRIEAEHMNLEGYKVVNVDPFEAASGYKAIVTTSNTTAGTASTVIGFETGTYTLAVNYFDVIRGKCSYVAYINDKVIGQWRGNSEEKLGHWPSEFLDGHSAIRINFPGVKVTKGDTLKIVGTPDGPEVAPLDYVSFLPNGIID</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEH4</accession>
    <name>E3QEH4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Actin-related protein 2/3 complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_04424</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
            <location evidence="7">Cytoskeleton</location>
            <location evidence="7">Actin patch</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the WD repeat ARPC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093300.1">
        <property type="nucleotide sequence ID" value="XM_008095109.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEH4"/>
    <dbReference type="STRING" id="645133.E3QEH4"/>
    <dbReference type="GeneID" id="24409789"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04424"/>
    <dbReference type="eggNOG" id="KOG1523">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034396_1_0_1"/>
    <dbReference type="OrthoDB" id="406844at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044396">
        <property type="term" value="P:actin cortical patch organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000601">
        <property type="term" value="P:positive regulation of Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000220">
        <property type="entry name" value="Actin-related protein 2/3 complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017383">
        <property type="entry name" value="ARPC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10709">
        <property type="entry name" value="ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10709:SF2">
        <property type="entry name" value="ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038093">
        <property type="entry name" value="ARP2/3_su1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="2 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="50"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR038093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ29280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="363" mass="39683" checksum="749133901C6C49E3" modified="2011-01-11" version="1">MAAPQVHHLFHAPIADHSFSADRQTLAIARDSTIELYEEAGSAFKLKDELKGHDKTVTSVDIAPNSGRIVSCSQDRNALVWEPSPTGYKPTLVLLRISRAATFVRWSPSETKFAVGSGDRVIAVCYFEEENDWWVSKHLKKPIRSTITSVAWHPNSVLLAAGSTDAHARVLSSFIKGVDARPEPTAWGERLPFNTICGEYLNNSAGWVHSVSFSPSGNALAFAAHDSSITVVYPSAPEQPPRAVVTITTQLLPFMSLLWSSEDEIIAAGYDCEAFRFKGGEDGWSLAGTLESKGRPGLSDAREESALNMFRQMDLKGKVKDDTQLKTVHQNTISTLRPYESSGGNLTKFSSSGVDGRIVIWST</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEI1</accession>
    <name>E3QEI1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_04431</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093307.1">
        <property type="nucleotide sequence ID" value="XM_008095116.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEI1"/>
    <dbReference type="STRING" id="645133.E3QEI1"/>
    <dbReference type="GeneID" id="24409796"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04431"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_4_3_1"/>
    <dbReference type="OrthoDB" id="47007at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48107">
        <property type="entry name" value="NADPH-DEPENDENT ALDEHYDE REDUCTASE-LIKE PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48107:SF26">
        <property type="entry name" value="OXIDOREDUCTASE, SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_4G05870)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ29287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="297" mass="32259" checksum="2423822DA9F102E4" modified="2011-01-11" version="1">MTDKGQFEEGYKVPVTDQEFPGKEGKLPVTPLFDRVPTPDGGSKLYQAAGKLEGLKAIITGGDSGIGRATAILFAMEGADSLIAYLPDEEEDAQETKKRVEDYGRKCYLVATDITDRANCQNIVDTALEKLGGIDILFNNAAYQMMVENIKDLKEEQWVHTFNTNIHPMFYLAKYALPHMKKGSTIINNASINAYIGRPDLLDYTSTKGAIISFTRGLSNQFCDKGIRVNAVAPGPVWTPLIPATMNEEAQKQFTSPIGRPSQPSEIATCVVFLASTDSASITGQTIHCNGGVIVNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QES1</accession>
    <name>E3QES1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Polysaccharide export protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_04521</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093397.1">
        <property type="nucleotide sequence ID" value="XM_008095206.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QES1"/>
    <dbReference type="STRING" id="645133.E3QES1"/>
    <dbReference type="GeneID" id="24409886"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04521"/>
    <dbReference type="eggNOG" id="ENOG502RJAT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040564_1_0_1"/>
    <dbReference type="OrthoDB" id="262547at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021047">
        <property type="entry name" value="Mannosyltransferase_CMT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34144">
        <property type="entry name" value="CHROMOSOME 8, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34144:SF7">
        <property type="entry name" value="EXPORT PROTEIN (CAP59), PUTATIVE (AFU_ORTHOLOGUE AFUA_7G05020)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11735">
        <property type="entry name" value="CAP59_mtransfer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ29377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="421" mass="47709" checksum="159ADAE78960D0A1" modified="2011-01-11" version="1">MGLLNGLRLGARRLLRSRGLRNLVLVFAVYTFLEALRVQRLVTGAPRHDPKRPRRVERVYIAGMHYNDAALIRDHWAGAVLALVEALGRDNVFVSVYESGSWDDSKAALLALDEELGRRGVRRNVVLDDRTHQEEVEAVPAQGEAREGWITTPRGKREMRRIPFLARLRNLTLKDLWKLGGEGEVFDKVLFLNDVVFTTDDVLALLDTNNGLYGAACSLDFSQPPYYYDTFALRDSAGQGHLMQTWPYFRSQVSREAMETYADAVPVRSCWNGIVAMPAAPFLVSRASGRRRLEFRAVPDSLAEEKHLEASECCLIHADNPLSESLGVFLNPRVRVGYSTGAYEWAHPRDAGDSWLSLWRIVVGTWEARVRRLLTSDRVKEWVVRKRLAEWEAEGDGREEKGVHCLINEGQVLVYNGWAHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>E3QES5</accession>
    <name>E3QES5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="14">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">GLRG_04525</name>
    </gene>
    <organism evidence="19">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 14">ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance. Capable of unwinding D-loops. Plays a role in limiting crossover recombinants during mitotic DNA double-strand break (DSB) repair. Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4 14">Interacts with the MHF histone-fold complex to form the FANCM-MHF complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 14">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="14"/>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093401.1">
        <property type="nucleotide sequence ID" value="XM_008095210.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QES5"/>
    <dbReference type="STRING" id="645133.E3QES5"/>
    <dbReference type="GeneID" id="24409890"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04525"/>
    <dbReference type="eggNOG" id="KOG0354">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002513_0_1_1"/>
    <dbReference type="OrthoDB" id="164902at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000400">
        <property type="term" value="F:four-way junction DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045003">
        <property type="term" value="P:double-strand break repair via synthesis-dependent strand annealing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18033">
        <property type="entry name" value="DEXDc_FANCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12091">
        <property type="entry name" value="FANCM_ID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18801">
        <property type="entry name" value="SF2_C_FANCM_Hef"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001992">
        <property type="entry name" value="ATP-dependent RNA helicase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000861">
        <property type="entry name" value="Fanconi anemia, complementation group M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1320.20">
        <property type="entry name" value="hef helicase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039686">
        <property type="entry name" value="FANCM/Mph1-like_ID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044749">
        <property type="entry name" value="FANCM_DEXDc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14025">
        <property type="entry name" value="FANCONI ANEMIA GROUP M FANCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14025:SF20">
        <property type="entry name" value="FANCONI ANEMIA GROUP M PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="16">
        <location>
            <begin position="189"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="17">
        <location>
            <begin position="533"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="714"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="756"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="883"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="17"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="32"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="63"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="88"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="151"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="728"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="921"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="941"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="952"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="1015"/>
            <end position="1040"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU367027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EFQ29381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1113" mass="123251" checksum="B97ABBDE44A2BB4C" modified="2011-01-11" version="1">MDSDEYDDDLADEDLVEALSQSQAGPSSSSAFNLQTAPSARSSAFTHALEPSFNRGNAGRQLPATNAFQKSASTRPLANELDDLPSDAFSSSPEPLSAAPPTRNAATAAPRAQNGLTRTSSSSFRQTTLLGGRVADDAPIQPSQPGFGRVYRGDKPEEAPSQHAIDREEMKTWLYPTNLGATRDYQFSIVKNGLFNNTLVALPTGLGKTFIAATIMLNYYRWTKDAKIVFVAPTKPLVAQQVDACFNIVGIPRSETTLLTGDTAPALRVNEWSSKRVFFMTPQTLQNDISHGYADPKSIVLLVIDEAHRATGEYAYAKVVKRIRQYNSYFRLLALTATPGSKIETVQEIIDNLGISHIEIRTEDSIDIRQYVHQRNVEQVVLDPSDEMCEIKDLFSKALKPLMDKLTQQNIYFGRDPMAITTYGLVKQQQEWFATVGRKTNPGMQFMMRAIFSILQSLAHAIKLLNFHGIRPFYENLKEFRGGVEDMGEKGSKYKKQIVNDQSFQEMMTRVEKWLRTEGFVGHPKLAALQDTVLNHFMDAGATSTRIIVFSEYRDSAEDIVRVLNVHKPLIKATVFVGQADSKRSAGMKQSEQIATIQKFKDGEYNVLVATSIGEEGLDIGQVDLIVCYDASSSPIRMLQRMGRTGRKRAGNIVLLLMRGKEEDAFARSKDNYAEMQKLICEGSKFNFRHDLSARIVPRDIRPEVNLQHIEIPIENTQNPSLPEPKKGRARKKLPPKKFHLPDGVSLGFVKASDMGKASAAPKRGRPQKKQEPTEADFVADVPSVNSVVLTETQLAELDRVYRSLPASWSKIEETEMPSLTACPELQRRLRPVGKVQHGQRTKRFVKLCQKLAKSQDTRSRYIQPFGEEDTSRWEEVAVPDYASDTEDGALPGNGARRQSKTVVSEDEPIEESRPKKRKSNSAPKRSAFTSATALVDDDMDKTADEETPPRRLPKPKKAATGRGRGKKASRRVGRGINSDELGDDCDRGSDVMETDGSDSGGDLLDFVVSDEHPVSSNHPSSSALPTSQATATGSTQRNDAAQPFYVPTEFPATQESADSLPDLADVLLSNKAKRSRTAASMDESEDGDATPRQQAGGRQQRRRAVFESDSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>E3QF77</accession>
    <name>E3QF77_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04659</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093535.1">
        <property type="nucleotide sequence ID" value="XM_008095344.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QF77"/>
    <dbReference type="GeneID" id="24410024"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04659"/>
    <dbReference type="HOGENOM" id="CLU_1578392_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="169" mass="18258" checksum="BD8524DDCF498811" modified="2011-01-11" version="1">MALLVPMGRMKAVGHAIRRRPDRLSEDKCSEIDIDWPVVGPGTQPRDRFRLSKGAIRTPPLILSGTKPLSAVLQRLAHSGGADGRWERLGMGRFRHEGPFADDVAVGCHRFWGAAAVVRDGGSGTLGRPGCGFPVPREGLGNEPVVVVGNVPVEREDPPLTKKNDDAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFE9</accession>
    <name>E3QFE9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Elongator complex protein 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_04731</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ELP6 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093607.1">
        <property type="nucleotide sequence ID" value="XM_008095416.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFE9"/>
    <dbReference type="STRING" id="645133.E3QFE9"/>
    <dbReference type="GeneID" id="24410096"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04731"/>
    <dbReference type="eggNOG" id="ENOG502SAXJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059771_0_0_1"/>
    <dbReference type="OrthoDB" id="9995306at2759"/>
    <dbReference type="UniPathway" id="UPA00988"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033588">
        <property type="term" value="C:elongator holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19495">
        <property type="entry name" value="Elp6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018627">
        <property type="entry name" value="ELP6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16184">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16184:SF6">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09807">
        <property type="entry name" value="ELP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ29587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="283" mass="29996" checksum="62335952AF5F28CD" modified="2011-01-11" version="1">MATRIPHALEGYLALPPECAQILLTGVLGATTNWLVLRHLYSYLRKPAANGEEATTAAAAAAEDVRVVFVSFMRDFAFWKEGAGRLGLDLEGLGRSGKFVFVDGLSGLFWQEGFAAQPAAAAAKGRRVLRGAKLPDIQRELEGAVADVSAEGAKTVLVLDQPDLLLAASGERLTGLALRNMLLDVQEKVHATVFAVAADEPLVASQTTTLEKEHAALVLGLAHAAETVIGLRLLDTGNASDVSGVLRITAGGDRHREREAVEETELLYFVGGDGSVKVFGRGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFS7</accession>
    <name>E3QFS7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">WD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_04906</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the ASTRA complex involved in chromatin remodeling.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093782.1">
        <property type="nucleotide sequence ID" value="XM_008095591.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFS7"/>
    <dbReference type="STRING" id="645133.E3QFS7"/>
    <dbReference type="GeneID" id="24410271"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04906"/>
    <dbReference type="eggNOG" id="KOG0319">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009276_0_0_1"/>
    <dbReference type="OrthoDB" id="5414888at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034388">
        <property type="term" value="C:Pwp2p-containing subcomplex of 90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034511">
        <property type="term" value="F:U3 snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000480">
        <property type="term" value="P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000472">
        <property type="term" value="P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:001009">
        <property type="entry name" value="Small nucleolar ribonucleoprotein complex subunit, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:001144">
        <property type="entry name" value="WD40 repeat-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013934">
        <property type="entry name" value="Utp13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19854">
        <property type="entry name" value="TRANSDUCIN BETA-LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19854:SF15">
        <property type="entry name" value="TRANSDUCIN BETA-LIKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08625">
        <property type="entry name" value="Utp13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="106"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="220"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="268"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="405"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="517"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="592"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="643"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="666"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="domain" description="U3 small nucleolar RNA-associated protein 13 C-terminal" evidence="7">
        <location>
            <begin position="719"/>
            <end position="867"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ29762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="892" mass="97442" checksum="4B2464F5B09A4E44" modified="2011-01-11" version="1">MASKQPFKTTFEPERVIRPIFTGGSVALDNGAKILATPLGEDAILTNPSNGKHLAKIEGDGEQISTLSLTPSGSHLIICSRSLSMKIYALKITEDGTVEAKLTRSLKPHGTPVVVLAVDRTSTLLATGGTDGAIKVWDIAGGYVTHTFRGPSVLVSALHFFEVAARSSEVEVEKAGKKGKKSNEAEENVTATTNWRLVSGSQDGKVRVWDLHKRAVIANLDSHVSNVQGLDYSPEQHAIVSASRDKTIIWWDAKSWKIRKVVPCLELVEAVGFTDGGRLTYSAGAKGCLRIWDTDTGRELTKDQPAKAEAESIVSAVSHSELPFILCVQVDHTLALYNVPQKESVEGCMPEPFRRISGTHDSIIDLNYLLPDRSLLALATNAEDIRIVSVKDSESTYFGQDLALLKGHDDIIVSLDVDWSGYWIATGAKDNNARLWRVDPANNSFTCHATFTGHTESIGAVTLPKQIPQESSAQFKDPLNHPPPFLLTGSQDQTVKKWEIPREAQSRKGGSRAVFTRKAHDKDINAMDVHPTSHLFASSSQDKMVKIWSVAEGEVQGILRGHRRGVWSVKFAPSGCPAIQGDEGQVAGKGVVLTGSADKTVKIWSLNDYTCIRTFEGHSNSVLKVVWLNMPKPEGKGKKQVQFASAGSDGLVKVWDANSGETETTLDNHEDRIWALAVNSADNTIVSGDGDSIVTFWKDTTPESQAAATQAAQKLIEQEQELENHIHHGSYRDAIVLALQLNHPGRLLSLFTSVVTSAPEPGSLCGLKAVDQVLATLSDEQIFTLLLRLRDWNTNARTAAVAQRILWTLVRSYPASKFSNLSVKGARGQRSLKEVLNALKVYTERHYRRTDELVDESYLVEYTLREMDSLAPAIEDVAMGNNIGAEEDVVMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFS8</accession>
    <name>E3QFS8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_04907</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EFQ29763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008095592.1"/>
    </dbReference>
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    <dbReference type="STRING" id="645133.E3QFS8"/>
    <dbReference type="GeneID" id="24410272"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04907"/>
    <dbReference type="HOGENOM" id="CLU_2468938_0_0_1"/>
    <dbReference type="OrthoDB" id="20872at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="entry name" value="Nucleoside phosphorylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ29763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="88" mass="9727" checksum="C541F714C2CE7F3C" modified="2011-01-11" version="1">MTCALSLEYDASVLAFDEIWADLENDLGKATQDPNIYTLGRIGKCNVIPVLLLDMGQVNTASASQSSLQFSQAQAGPSLWRMWQRPQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFW7</accession>
    <name>E3QFW7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GPI transamidase component PIG-S</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_04946</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093822.1">
        <property type="nucleotide sequence ID" value="XM_008095631.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFW7"/>
    <dbReference type="STRING" id="645133.E3QFW7"/>
    <dbReference type="GeneID" id="24410311"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04946"/>
    <dbReference type="eggNOG" id="ENOG502RS78">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067144_0_0_1"/>
    <dbReference type="OrthoDB" id="5338512at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ29802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="255" mass="28016" checksum="A8779C7356ED5968" modified="2011-01-11" version="1">MADYFCCPSDTTCLVLAENTTALCCPKGASCDVISPIICDITAQNVIENPTSPIHTTKLKESLPSCGNTEVSHQHASLAHNEHKDHDVGNANGNPGNDVDTFRERSRGIETISQPGPGAFNTPGHGGIIAGTTVAAVASAALLTCLLWLKRRSISEKVGSVRWFPRPWQQLRERGSEQDVSLPRYNSPPPAYTIEMKPPFKHTAFRHYSPDSVGDIVPVELPATPVSFSVWYVREEGEVRRPRTHYEPYRRPSGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QG16</accession>
    <name>E3QG16_COLGM</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_04995</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093871.1">
        <property type="nucleotide sequence ID" value="XM_008095680.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QG16"/>
    <dbReference type="STRING" id="645133.E3QG16"/>
    <dbReference type="GeneID" id="24410360"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04995"/>
    <dbReference type="eggNOG" id="ENOG502SZVV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1440956_0_0_1"/>
    <dbReference type="OrthoDB" id="4811426at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ29851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="188" mass="20720" checksum="A6EA9D9BEBBB6BCF" modified="2011-01-11" version="1">MWRLLASTVLAANEGGEHVDHVGSLKGLDWAADAFNSLFPQLEAAVVRVIGYSKGLPTPATYLDEKRVPPGIWASLNDVLTDCSRTASLLNTCTKAFDDRRVYPDAAKRGPGFSGPNNVVVFMKWPILAYLVQLWFERKADDGFHTTLAHSDVPGDERQNIIDWFGSKSGSPDTILDRAMVRRSIITS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGG0</accession>
    <name>E3QGG0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Eukaryotic integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_05092</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ29948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093968.1">
        <property type="nucleotide sequence ID" value="XM_008095777.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGG0"/>
    <dbReference type="STRING" id="645133.E3QGG0"/>
    <dbReference type="GeneID" id="24410457"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05092"/>
    <dbReference type="eggNOG" id="KOG2890">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043563_1_0_1"/>
    <dbReference type="OrthoDB" id="73612at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1540.10:FF:000004">
        <property type="entry name" value="Transmembrane protein 115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013861">
        <property type="entry name" value="TMEM115/Pdh1/Rbl19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13377">
        <property type="entry name" value="PLACENTAL PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13377:SF3">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08551">
        <property type="entry name" value="DUF1751"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01160">
        <property type="entry name" value="DUF1751"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="268"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="305"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="331"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="354"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ29948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="366" mass="40229" checksum="59F58C472864A019" modified="2011-01-11" version="1">MPPRINIPPVTRALLAVLLVQSFLSAAIRYRQWSATSEIVIPYLTLIPQLSLIYPWTFLTSTFVENNIFTLGIACVTIYQGGRYLERAWSSAELAKFVVITALVPNILTFALMIIFFTLTRNERWTLTVIGGSIPMQISFLVAFSQLVPAHTVTLFRGILSLRVPRFPLLYLGIVFVLSLTPLLTTASFSLAVSGFLTSWTYLRFYKTVFPDLDSSQPTSLRGDASETFAFAEFFPAPVKPFVATVSAQIFEVLVAMRLCTPFSDNGPAGRGNNYIQRSAPGGARAEAERRRALALKTLDQRLQAATAGNAATRSPSQPPAQQPTGPTVHTQPQPNTQTAMTTQPTAMLGETNYHPEQDSSEKSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGI9</accession>
    <name>E3QGI9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mechanosensitive ion channel protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_05121</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ29977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093997.1">
        <property type="nucleotide sequence ID" value="XM_008095806.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGI9"/>
    <dbReference type="GeneID" id="24410486"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05121"/>
    <dbReference type="eggNOG" id="KOG4629">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010480_0_1_1"/>
    <dbReference type="OrthoDB" id="544685at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005262">
        <property type="term" value="F:calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016688">
        <property type="entry name" value="MscS-like_plants/fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058650">
        <property type="entry name" value="Msy1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31323">
        <property type="entry name" value="MECHANOSENSITIVE ION CHANNEL PROTEIN MSY2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31323:SF14">
        <property type="entry name" value="MECHANOSENSITIVE ION CHANNEL PROTEIN MSY2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25886">
        <property type="entry name" value="Msy1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017209">
        <property type="entry name" value="Memb_At2g17000_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="463"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="494"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="407"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="33"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="708"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="751"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="47"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="64"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="764"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="827"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="876"/>
            <end position="894"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR017209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ29977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="894" mass="97913" checksum="F7084E86A012DB93" modified="2011-01-11" version="1">MPGPLSPRHSGFLPINNGHSIDMAESDIPLTQVRSAASTGARKPAMNVSNTEDSGSGTNEKHGLFQRHNKGGRRKKHGELGRKGTGGSDDFKVNAMGRFYNKITGASVVTRYLVYIIPIGLLLGVPLVVLPLTGHRKDVLVGGTKGKPLFDLFLWIEIAWLTLWAGKCVAWVLPHAFMFFCGVVSSGTRKYATVLQNLQIAFSLFFWALASWQSFQALFSRNNPDPAPWIITMIRLLGATFVSSAVYLGEKAIVQLIGISYHQRSFALRIKESKHEIRLLGLLYDASRTLFPMYCPEFEDEDYVINDSLDLILAKAAKGGQGSATPLRLVGDIGRMGDKITGVFGNIASEITGKQVFNPNSAHSIVVEALEKTKPSEALARRIWMSFVVEGKDSLYPDDFHEVLGPAYSEEAEEAFGMIDNDMNGDISLDEMTRKVVEIGKERKAITEGMKDIGQALRVFDKVLMFVVVLIVVFIFLAWFQSSFLTTVATAGTALLSLSFVFAVTTQEFLGSCIFLFVKHPYDVGDRVDIVGSEKQQLIVDKISLLYTVFTRIDKMQVVQVPNITLNNLWIENVTRSKAMKEVIDLNVSFDTSFEDIELLRLEMESFVRSPDNSRDFMPDIAIGVGGVGDLDKLQLKIAIKHKSNWHNDAVRATRRSKFMCALAMAIKKIPIYAPGGGSEALGAPGNPSYSVAVSDEVAAAARKNAAKAKEAKRLVPSPAAEGTSTKPDSKTEKQAVQELNLRDPLVEEDWGYRVGDDDTLSGSRDRRSTEIERVRNELLKRASTKGGGGRRKPGETIPLSPVGDGPGLGLTQTTSRSRAYDEEAETGVSESYSSTYYGGQSSTYATYGQSLSPTVSPPHPLQSAPAAGQRPRGRSVSNTQQQNEAAQSSQKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGR8</accession>
    <name>E3QGR8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_05200</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ30056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094076.1">
        <property type="nucleotide sequence ID" value="XM_008095885.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGR8"/>
    <dbReference type="GeneID" id="24410565"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05200"/>
    <dbReference type="eggNOG" id="ENOG502T4JZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070617_0_0_1"/>
    <dbReference type="OrthoDB" id="10039566at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022185">
        <property type="entry name" value="DUF3712"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046368">
        <property type="entry name" value="Tag1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35895">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35895:SF1">
        <property type="entry name" value="LIPID-BINDING SERUM GLYCOPROTEIN C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12505">
        <property type="entry name" value="DUF3712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ30056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="251" mass="27185" checksum="115C527A268D4804" modified="2011-01-11" version="1">MEAITQAIMNRSKLEVETIQISNPTAESFVMTIVSRVTGTGPMGATMAPMTVDMMFNGACFGKLDLPEVKTKSGGTDVIVRDQVIKIVDRNAFKAFVKAIMCDEQLVLHLDNGDCTIKALGLSAKVKYAKDVHIIGMGGPKIAQVNVQERGGGFVNTMKVYNPSPLEIDHGVSIFEIRNESGEVLSELKGDLKIVKGDFETTFQGSIKKGAKASDKARLVGVGTQESNWCDETIKFIDVSFSVSPQFANML</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>E3QH82</accession>
    <name>E3QH82_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcription factor PAP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_05388</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the bZIP family. YAP subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697348">
        <property type="protein sequence ID" value="EFQ30244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094264.1">
        <property type="nucleotide sequence ID" value="XM_008096073.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QH82"/>
    <dbReference type="STRING" id="645133.E3QH82"/>
    <dbReference type="GeneID" id="24410753"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05388"/>
    <dbReference type="eggNOG" id="ENOG502RPD7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011807_0_0_1"/>
    <dbReference type="OrthoDB" id="5380163at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090575">
        <property type="term" value="C:RNA polymerase II transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.170:FF:000067">
        <property type="entry name" value="BZIP transcription factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.100">
        <property type="entry name" value="YAP1 redox domain. Chain B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050936">
        <property type="entry name" value="AP-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013910">
        <property type="entry name" value="TF_PAP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023167">
        <property type="entry name" value="Yap1_redox_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621:SF6">
        <property type="entry name" value="AP-1-LIKE TRANSCRIPTION FACTOR YAP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621">
        <property type="entry name" value="TRANSCRIPTION FACTOR KAPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08601">
        <property type="entry name" value="PAP1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111430">
        <property type="entry name" value="YAP1 redox domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="6">
        <location>
            <begin position="158"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="33"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="95"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="262"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="322"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="33"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="139"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="174"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="277"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="323"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ30244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="572" mass="61320" checksum="66AD78176B4CDA0F" modified="2011-01-11" version="1">MASATNSGFPTNFILTPQQQSLLFAALNSNKQQLANQSPATTTKDTSMSPSSYQTSPAQGAAHGFQESPYLDNYDYDFGDSSFDFDVSTVGQGKMIGDIPGGAQSAQSTKSDSTENDGTDKRAHPDDEEDEDSPGNGAKRREGSEKVPKKPGRKPLTSEPSSKRKAQNRAAQRAFRERKEKHLKDLETKVEELEKASKDANSENSQLRAQIERMTAELNEYKTKMAAMSTRSVPHTKSPMGFGASAIGNLSDVNFQFEFPKFGVLPGSQMPNKPAQSTRSSSSPNANESNPVSPLDKNNSSGAFAGLDFGTKDDLTNFTSLFSPSLATGSTGTGTSRTSVDSGLYGINNGTSTSSPSASSQSNGGGPSSSCGTSPEPFTQSPMGFKPVDTMTTIGEESANQQSLFAGIDTGNFDWLAQQNGGQFDPQLFGDYREPQDNVLAGTTFDDSFFNDAIDADFITPYNMALSPAVPKKNLIDQIDAAKNADDDLIKEAVKADNYNCNKIWEKLQSCPSVQAGEFDLDNLCSELQKKAKCSGQGPVVSETDFQTVVNKWMGKDAAACFNGQEKNKTKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3QH92</accession>
    <name>E3QH92_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetylglucosamine-6-phosphate deacetylase</fullName>
            <ecNumber evidence="2">3.5.1.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_05398</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate</text>
            <dbReference type="Rhea" id="RHEA:22936"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:57513"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="EC" id="3.5.1.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="10">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. NagA family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.25" evidence="2"/>
    <dbReference type="EMBL" id="GG697348">
        <property type="protein sequence ID" value="EFQ30254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094274.1">
        <property type="nucleotide sequence ID" value="XM_008096083.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QH92"/>
    <dbReference type="STRING" id="645133.E3QH92"/>
    <dbReference type="GeneID" id="24410763"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05398"/>
    <dbReference type="eggNOG" id="KOG3892">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032482_0_0_1"/>
    <dbReference type="OrthoDB" id="10264777at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008448">
        <property type="term" value="F:N-acetylglucosamine-6-phosphate deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006046">
        <property type="term" value="P:N-acetylglucosamine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00854">
        <property type="entry name" value="NagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000065">
        <property type="entry name" value="N-acetylglucosamine-6-phosphate deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003764">
        <property type="entry name" value="GlcNAc_6-P_deAcase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00221">
        <property type="entry name" value="nagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11113">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11113:SF14">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038994">
        <property type="entry name" value="NagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="11">
        <location>
            <begin position="65"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="8">
        <location>
            <position position="309"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="252"/>
            <end position="253"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="347"/>
            <end position="349"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR038994-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR038994-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR038994-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ30254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="439" mass="46906" checksum="36D2F0F3F44358D4" modified="2011-01-11" version="1">MPIATPKTPKNGITKFTNCRLVKGDALVQEDIWVSSVTGKIIHSQAAFFDDLSLPDETINLGGRIVSPGLIDCQLNGAFGFNFSTLLEDMTQYGKKVRELNKKLVATGVTSYVPTLTSQRPELYQKALPYLGPSGGSQAARDGAESLGAHVEGPFLSPSKNGVHNVDVLQEAETFDDLKDCYGVENIEPTANGATIPIKMITAAPERGNMTDIIPELRKRGIIYSIGHSEATYEEASAAVAAGATMITHLFNAMRPLHHRNPGVFGVLGTAERLNRPYFGIISDGIHLHPTTIKIAFNAHPDGFILVTDAMHMMGLADGSYQWTNGQNVNNIIKVGSTLLLEGTNTIAGSALTLMECVNNFLRWSGTGIPKALKAVTATPAAMLGLQGVKGSLEDGADADLVVLSEEVRDGATQLVVDEVWKAGALVSSRKENQSPITP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHP2</accession>
    <name>E3QHP2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10 11">Endo-1,4-beta-xylanase</fullName>
            <ecNumber evidence="4 10 11">3.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_05524</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10 11">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-xylosidic linkages in xylans.</text>
            <dbReference type="EC" id="3.2.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10 11">Glycan degradation; xylan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10 11">Belongs to the glycosyl hydrolase 11 (cellulase G) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.8" evidence="4 10 11"/>
    <dbReference type="EMBL" id="GG697349">
        <property type="protein sequence ID" value="EFQ30380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094400.1">
        <property type="nucleotide sequence ID" value="XM_008096209.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHP2"/>
    <dbReference type="GeneID" id="24410889"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05524"/>
    <dbReference type="eggNOG" id="ENOG502RXA7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052631_0_0_1"/>
    <dbReference type="OrthoDB" id="2115822at2759"/>
    <dbReference type="UniPathway" id="UPA00114"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031176">
        <property type="term" value="F:endo-1,4-beta-xylanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.180:FF:000001">
        <property type="entry name" value="Endo-1,4-beta-xylanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013319">
        <property type="entry name" value="GH11/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018208">
        <property type="entry name" value="GH11_AS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033119">
        <property type="entry name" value="GH11_AS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033123">
        <property type="entry name" value="GH11_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001137">
        <property type="entry name" value="Glyco_hydro_11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46828">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46828:SF2">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00457">
        <property type="entry name" value="Glyco_hydro_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00911">
        <property type="entry name" value="GLHYDRLASE11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00776">
        <property type="entry name" value="GH11_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00777">
        <property type="entry name" value="GH11_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51761">
        <property type="entry name" value="GH11_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8 10 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 10 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10 11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="5 10 11" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180426" description="Endo-1,4-beta-xylanase" evidence="12">
        <location>
            <begin position="20"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="GH11" evidence="13">
        <location>
            <begin position="41"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ30380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="232" mass="25649" checksum="CA065C18E060B66D" modified="2011-01-11" version="1">MVSFKFLLLATAAVTAVLGRPFDFLDEVDDGNSTEVLERRQVTPNSEGTHNGYFYSFWSDGGGRVQYTMGAGSRYSVSWSNVGNFVGGKGWNPGNGRTINYGGSFSPNGNGYLAVYGWTRNPLVEYYVVESYGTYNPSSGGQYKGTVTTDGGTYDVYVSTRYNQPSIDGTRTFQQYWSVRQGKRVGGSVNMQNHFNAWARYGLNLGTHYYQIVATEGYQSSGSSDIYVQTSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIM9</accession>
    <name>E3QIM9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">CFEM domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_05783</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094659.1">
        <property type="nucleotide sequence ID" value="XM_008096468.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIM9"/>
    <dbReference type="STRING" id="645133.E3QIM9"/>
    <dbReference type="GeneID" id="24411148"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05783"/>
    <dbReference type="eggNOG" id="ENOG502SKG6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_25_2_1"/>
    <dbReference type="OrthoDB" id="2496787at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF143">
        <property type="entry name" value="EXTRACELLULAR MEMBRANE PROTEIN CFEM DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="25"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ30639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="200" mass="22620" checksum="96685CC89C5D1059" modified="2011-01-11" version="1">MVTFPELRVSPSFFSGVSDESPGHHLGVGRDVWALSSEQITRFLHGFFVFEVIYTLSISTLKASFLFFYIRVFNMVSNTFTAVLWATQAFNIAFCIAFTIANLAQCQPFSNAWKAWDGKHPGHCINVYAMFVSHAVINIALDVWLLILPTTQVLWLNMRKRQKAEIMFMFGLGAVIAVFSAIRLKVLVSLEGFRDPTCKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJ56</accession>
    <name>E3QJ56_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">GPR1/FUN34/yaaH family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_06038</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094914.1">
        <property type="nucleotide sequence ID" value="XM_008096723.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJ56"/>
    <dbReference type="STRING" id="645133.E3QJ56"/>
    <dbReference type="GeneID" id="24411403"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06038"/>
    <dbReference type="eggNOG" id="ENOG502QUJS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051062_0_1_1"/>
    <dbReference type="OrthoDB" id="3648309at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015123">
        <property type="term" value="F:acetate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051633">
        <property type="entry name" value="AceTr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000791">
        <property type="entry name" value="Gpr1/Fun34/SatP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047622">
        <property type="entry name" value="GPR1_FUN34_YAAH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF038013">
        <property type="entry name" value="AceTr_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123:SF1">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01184">
        <property type="entry name" value="Gpr1_Fun34_YaaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01114">
        <property type="entry name" value="GPR1_FUN34_YAAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="153"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="206"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="241"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ30894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="298" mass="32201" checksum="4CC31BC936DFF78F" modified="2011-01-11" version="1">MATHETLNHNAVPPADVEKDVHTSGADHYNGVQADQNAAYARQTGPFTRVADYQNMTEGQAQAFGGTLQPGLWKPYEHRKFANPAPLGLSAFALTTFVLSCVNLQARGVKAPNIAVPLAFGYGGLVQLLAGMWEMAVGNTFGATALSSYGGFWIAYGILLTPAWGIIAPDGPYAADYSDHYSAVGFFLTGWFIFTTLLLLCTLRSTVVFFSLFFTLDLAFLFLACENYAANNGALTASRNLQICGGTFGMLAAFLAWYCALAGLQDDSNSFFQVPVFHLPWSDKGKELRKAKSNRSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJ79</accession>
    <name>E3QJ79_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetyl esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_06061</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ30917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094937.1">
        <property type="nucleotide sequence ID" value="XM_008096746.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJ79"/>
    <dbReference type="GeneID" id="24411426"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06061"/>
    <dbReference type="eggNOG" id="ENOG502RY46">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015101_1_0_1"/>
    <dbReference type="OrthoDB" id="1600564at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01846">
        <property type="entry name" value="fatty_acyltransferase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051058">
        <property type="entry name" value="GDSL_Est/Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648">
        <property type="entry name" value="GDSL LIPASE/ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648:SF22">
        <property type="entry name" value="GDSL LIPASE_ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180589" evidence="2">
        <location>
            <begin position="18"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ30917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="344" mass="37590" checksum="3616FDE59431E1CC" modified="2011-01-11" version="1">MLSLPIAALVSVAATSGVGFNKFENLVTFGDSYTDEGRLNYFINNNGSAPPAGVLLPPSNSTASGGYAWGRFVASSTGAKYYDYAVGGATCSNKIVSRDFVSIHQPFPSVLDYEIPAYRADTAFDALYPNREANNTIYALWIGTNDLGYLGFLTDSNAPGTTISSHVDCVWEVFDKIHATGGRHFVLLNVAPLEQSPLYAATELGGFGDSVFWPNKTSYNTTETQYKMLEYSTSINTAFDYGVPFHLLVKKRWPGAIFSIFDVHSLLRDVHAEPSKYLSSPPNVKAPYRACDPVTAACVDSSEPKASFLWYDELHPSERTSEIVAQHFVNVVYGNSTYGKTYAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJA9</accession>
    <name>E3QJA9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Prp 4 CRoW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_06091</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ30947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094967.1">
        <property type="nucleotide sequence ID" value="XM_008096776.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJA9"/>
    <dbReference type="STRING" id="645133.E3QJA9"/>
    <dbReference type="GeneID" id="24411456"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06091"/>
    <dbReference type="eggNOG" id="ENOG502RZBP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078841_1_0_1"/>
    <dbReference type="OrthoDB" id="5409186at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180472" description="Prp 4 CRoW domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ30947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="271" mass="27071" checksum="6F04DE39967B09C0" modified="2011-01-11" version="1">MQIRSLASLAYVAFAAQAFAQQTKVFKRSVTFGRDLGFMRRADSGYQPADELCNKGGNTCAEACGGGYQQCKSTDQAVHCYNPAAGETCCSTTSGNSCLSSFYCTHDPKADTICCPNGMNLGDCAAKHGVAGALTSDVPVPTTTSVPSTSPSSTVPPTTTSAPPTTTSISSVVVTTTSTSSNTSTIVSTSEVPASTEAPTSFSPSAGTSTAFLALNGTTLATGSTRSSARSTLFPSAAATTTAASAQSAGNSNGPAGMAVILGAAFVAALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJU6</accession>
    <name>E3QJU6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_06278</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697353">
        <property type="protein sequence ID" value="EFQ31134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095154.1">
        <property type="nucleotide sequence ID" value="XM_008096963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJU6"/>
    <dbReference type="STRING" id="645133.E3QJU6"/>
    <dbReference type="GeneID" id="24411643"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06278"/>
    <dbReference type="eggNOG" id="KOG1577">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_0_0_1"/>
    <dbReference type="OrthoDB" id="5945798at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd19071">
        <property type="entry name" value="AKR_AKR1-5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000002">
        <property type="entry name" value="2,5-diketo-D-gluconic acid reductase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="2,5-DIKETO-D-GLUCONIC ACID REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827:SF3">
        <property type="entry name" value="NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00798">
        <property type="entry name" value="ALDOKETO_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="7">
        <location>
            <begin position="21"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="6">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ31134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="329" mass="36826" checksum="A4D534B21D2DF429" modified="2011-01-11" version="1">MAPPVCTKTFKLNNGLDFPAVGLGTWQGKQAPLRTDDSKALEESIIHALKVGYRHIDTAQLYGVEEVVGRAIRNSGVPRSEIIVVTKFWGNWHHDPAKALQISLDTLGLDYIDVFLMHWPWATTPAPEMKVLKKWESPTFIETWKMMEPLVGEKCRAIGVSNFMPKVMDELLAEAKIVPAINQVELHAFNPNLNLVPYCQEKGIVVTSWSTLGGSSAAQNEILTHELFTSIAKAHDVSTGVVSLSWAVQRGIAVIPKSANKARIEENIRLVTLTDEEMRKINEAHKTIKRERLSNNIASQHMEIDGKMTQQGWTYVDMGYEDENGNWLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>E3QK60</accession>
    <name>E3QK60_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Autophagy-related protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_06392</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Preautophagosomal structure membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697354">
        <property type="protein sequence ID" value="EFQ31248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095268.1">
        <property type="nucleotide sequence ID" value="XM_008097077.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QK60"/>
    <dbReference type="STRING" id="645133.E3QK60"/>
    <dbReference type="GeneID" id="24411757"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06392"/>
    <dbReference type="eggNOG" id="KOG0583">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_172_2_1"/>
    <dbReference type="OrthoDB" id="541276at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010506">
        <property type="term" value="P:regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13993">
        <property type="entry name" value="STKc_Pat1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000549">
        <property type="entry name" value="Protein serine/threonine kinase (Ran1), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045269">
        <property type="entry name" value="Atg1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24348">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24348:SF68">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE ATG1C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0072">Autophagy</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="56"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="360"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="363"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ31248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="510" mass="56731" checksum="BCD265D78784DFE1" modified="2011-01-11" version="1">MQHVSGFGYPTPPASPVYDNSKCSLQQPITTAPHCQARYVPLTPEARLGRFLEGKLQLTTILGTGAYGVVYSAVDVKTGVRYAVKCLSKFNPDGTPLDRRQVAFQNREIRLHYLASAHPNVVSMLKIVDDPDCIYVILEYCPEGDLFFNITEGGQYVGNDDLAKRVFLQILDAVEHCHSLGIYHRDLKPENILVSDHGETVKLADFGLATSSDRSEDYGCGSTFYMSPECLDHYARRPFYFCAPNDVWSLGVILVNLTCGRNPWKQASFEDSTYRAYTRCPDTLKSILPVSDELNDILGRIFTRNPDQRITLPELKARIQACRSFTIPAMPTAVLPTPPASPEHMTEYVTCEDTIVDDYDNALSPASSSSDDGSTCSSDDGSLTSSGSTIDDLDEEFLQEQHEAMVCHAQTFEPEDPRTASFPTQEFVPQQYTGPVPSPAVGQEHLHAHMPIPGHMPVQVQMQAPSCPPKSFVQFWWGDVLKYAQHAPSMHPHVPFHHQVPLFSHPQGCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKF9</accession>
    <name>E3QKF9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_06491</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697354">
        <property type="protein sequence ID" value="EFQ31347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095367.1">
        <property type="nucleotide sequence ID" value="XM_008097176.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKF9"/>
    <dbReference type="STRING" id="645133.E3QKF9"/>
    <dbReference type="GeneID" id="24411856"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06491"/>
    <dbReference type="eggNOG" id="KOG0252">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_46_12_1"/>
    <dbReference type="OrthoDB" id="2261376at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046943">
        <property type="term" value="F:carboxylic acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030643">
        <property type="term" value="P:intracellular phosphate ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000140">
        <property type="entry name" value="Putative MFS phospholipid transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23508">
        <property type="entry name" value="CARBOXYLIC ACID TRANSPORTER PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23508:SF10">
        <property type="entry name" value="CARBOXYLIC ACID TRANSPORTER PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="172"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="208"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="297"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="326"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="353"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="393"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="429"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="36"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="484"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ31347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="509" mass="54783" checksum="57C1192E481EBD6A" modified="2011-01-11" version="1">MFNFARKKSSESEAAARETVAAADAPSKPFREAIVPVIACGAGLFSDGYINNVIGSVTTVLALQYGDLYKTSNAKKYVGDIAFAGTVVGQLAFGWLADHWSRTNSLLVSTVILVVFTALAAGSYYKSEPVGMFNMLAAWRFFVGIGIGGEYPAGSVGAAESTGELKSGSRNLWFIMFTNTMIDWGFVIGAFVPYVVAAACQNGHYSTIWRTSLGIGVVFPIFLFVLRLFVKEPAEFTKNSMRYAKTPYLLSLKFYGWRLFVVSLIWFIYDFSAYSFGIYSSTILSNLYGDTAPLTTVFGWNTVINLFYIPGTMLGAPASDWLGPRYALALGVFLQAVVGFIMAGDYFNLSQPGMVGGFVVVYGVFLALGEFGPGNNIGLLAAKTCATGIRGKYYGVAAAIGKIGAFVGTWVFPYIQAAAGDNAVASAQYPFWVSSSLCVLSAALAVFCLPHIGQDTIALEDARYRAYLEANGYDTRQLGLKRGETVESTESVSPVEGISEATKEGKTMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKH3</accession>
    <name>E3QKH3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C6 zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_06505</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697354">
        <property type="protein sequence ID" value="EFQ31361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095381.1">
        <property type="nucleotide sequence ID" value="XM_008097190.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKH3"/>
    <dbReference type="STRING" id="645133.E3QKH3"/>
    <dbReference type="GeneID" id="24411870"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06505"/>
    <dbReference type="eggNOG" id="ENOG502RSG2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013866_4_1_1"/>
    <dbReference type="OrthoDB" id="4491390at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053175">
        <property type="entry name" value="DHMBA_Reg_Transcription_Factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38791:SF13">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38791">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="361" mass="41316" checksum="FB87763AEEFFCC19" modified="2011-01-11" version="1">MACLAMQQAKGMRGPALVRAQEHHVNALRAVRRAIADPIEVENDQTLGAVLMLAFYETLMSKDSMKEYMSHVKGAAKIIRMRGQKCLETDEGREMFALTRNQCILIQNLFKGTEMSEYSWLLHNETSQRVNRETADMNIYYTRLQQCVDSLIAKARHPGPEAIDEMVELLGKCRKLENEFRQLKDNINPLWKVEVAEWVFDRTDEELDTEPTFEGPVYKFYNLPVAVLHIISWCFHLNLISTMMRCSSWLASAGKEELGVLDDYETLARLSTDCVHDIVSGVPYFCNWNAYGVVVSQFPCGLTKPDDPLKGEAGLIVMWPIAIAIKSDYATPRQRRYLRGRLRYIADVSGINQARYFINEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKR5</accession>
    <name>E3QKR5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">HTH APSES-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_06597</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697355">
        <property type="protein sequence ID" value="EFQ31453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095473.1">
        <property type="nucleotide sequence ID" value="XM_008097282.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKR5"/>
    <dbReference type="STRING" id="645133.E3QKR5"/>
    <dbReference type="GeneID" id="24411962"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06597"/>
    <dbReference type="eggNOG" id="KOG4177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009666_3_1_1"/>
    <dbReference type="OrthoDB" id="6718656at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030907">
        <property type="term" value="C:MBF transcription complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033309">
        <property type="term" value="C:SBF transcription complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048315">
        <property type="term" value="P:conidium formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030435">
        <property type="term" value="P:sporulation resulting in formation of a cellular spore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.260.10:FF:000001">
        <property type="entry name" value="APSES transcription factor (MbpA)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.260.10">
        <property type="entry name" value="Transcription regulator HTH, APSES-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036887">
        <property type="entry name" value="HTH_APSES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018004">
        <property type="entry name" value="KilA/APSES_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051642">
        <property type="entry name" value="SWI6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003163">
        <property type="entry name" value="Tscrpt_reg_HTH_APSES-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43828">
        <property type="entry name" value="ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43828:SF15">
        <property type="entry name" value="TRANSCRIPTION FACTOR MBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04383">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01252">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54616">
        <property type="entry name" value="DNA-binding domain of Mlu1-box binding protein MBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51299">
        <property type="entry name" value="HTH_APSES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0183">Conidiation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0749">Sporulation</keyword>
    <feature type="domain" description="HTH APSES-type" evidence="9">
        <location>
            <begin position="10"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="266"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="388"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="111"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="435"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="497"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="135"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="170"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ31453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="691" mass="77637" checksum="AAB41C77A148B3F1" modified="2011-01-11" version="1">MVKGNAQPGIYSATYSGIPVYEFQFGDDLKEHVMRRRQDDWINATHILKAAGFDKPARTRILEREVQKEKHEKIQGGYGKYQGTWIPLDKGVALAQRNNIYDRLRLIFEYTPGDQSPPPAPRHTSKPKAPKKPAVPKWPGTNIQQQHQQQLPPQVQPPANSAQAAPPPAEEYDIGDSVMNDDDTPDNLTVASASYMGEDDRFDLSHQSTGHRKRKREEAIQDLTQQQHSVYGDELLDYFLLSRNEKPAYRPEPPPNFQPNWIIDSEEHTALHWASAMGDVDVIKQLRRFGASLSVQNVRGETPFMRAVHFTNCYEKQTFPQVMKELFDTVDARDASGSTVIHHAAVMKNGRVVSHSCSRYYLDNILNKLQETHDPAYVQQLIDAQDEQGNTALHLAAQRNARKCIRALLGRQASTNIPNSEGVRSEDLIAQLNATKKERGPQRSSSPFAPDSQRHVSFRDTMPERMTASKKLALSSFSSEAANTVYARITPLIMEKFQDLAGSYDEELREKDQAEKEARRILSNTQAEIAAVRQQIAELEAQLEPDDGAAQIMSEANRAKHQVMSLITHQNRLHVQQAVDQEISKLNGDVDEASYEDRLSLAKQLQAMLSEQRQSESDYVEALSMVGTGENIDKYRRLLRKCLPPADAENLDENLDNLIEMMEEDRDLPGDGSGLEPMDVGMGGIGIGIGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QL33</accession>
    <name>E3QL33_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cofilin/tropomyosin-type actin-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_06860</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the actin-binding proteins ADF family. Coactosin subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697356">
        <property type="protein sequence ID" value="EFQ31571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095591.1">
        <property type="nucleotide sequence ID" value="XM_008097400.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QL33"/>
    <dbReference type="STRING" id="645133.E3QL33"/>
    <dbReference type="GeneID" id="24412225"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06860"/>
    <dbReference type="eggNOG" id="KOG3655">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129657_0_0_1"/>
    <dbReference type="OrthoDB" id="20822at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030864">
        <property type="term" value="C:cortical actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030427">
        <property type="term" value="C:site of polarized growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11282">
        <property type="entry name" value="ADF_coactosin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.20.10:FF:000018">
        <property type="entry name" value="Coactosin-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002108">
        <property type="entry name" value="ADF-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10829:SF56">
        <property type="entry name" value="ADF-H DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10829">
        <property type="entry name" value="CORTACTIN AND DREBRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00102">
        <property type="entry name" value="ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51263">
        <property type="entry name" value="ADF_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADF-H" evidence="6">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ31571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="146" mass="15966" checksum="5AC9F1E6C56401A6" modified="2011-01-11" version="1">MSGLDAPEIAAAYDAVRSDKDETNWLLISYASAVGNKLTLTKTGTGGIAELAKELDDSQVQYAYVRVEYANDAESKRVKFAFVIWIGESTKIMRKARVSIESSEVKRVLPHHSITVNASDKADLDEDDIIKRLRKAGGADYNGGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QL41</accession>
    <name>E3QL41_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">GMC oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_06868</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697356">
        <property type="protein sequence ID" value="EFQ31579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095599.1">
        <property type="nucleotide sequence ID" value="XM_008097408.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QL41"/>
    <dbReference type="STRING" id="645133.E3QL41"/>
    <dbReference type="GeneID" id="24412233"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06868"/>
    <dbReference type="eggNOG" id="KOG1238">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002865_6_1_1"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF115">
        <property type="entry name" value="DEHYDROGENASE XPTC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="4">
        <location>
            <begin position="43"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="5">
        <location>
            <begin position="482"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="565"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="608"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ31579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="621" mass="67614" checksum="A6F62BE81B96D3EA" modified="2011-01-11" version="1">MRRMYLLKALSTGVCILGGLVEALRGRAHHLAKRQVTELRQEYDFVVVGGGTAGLTIADRISDAFPMKTILVIEYGEIEGTVGYYDPPEDGRGASRLVITSPPVASVNNRTATVILGMTVGGGSAVNGQFLDRGSRYDYDEWAHLGSPQFDDSPDTWDWENLGPAFKKSLFLTEPREELAQKYGYTWDASAYTGDSIEASFPPFQWPIQRIGWQAFEEFGLETPVTCDNGDKHGVCWVPSAQNSETVERSHAGVGHYRRIAKTRPNLDLLVGHKVMRLIIDKNMGAPAVEFRPVEGGEARTIRPKREVILSAGAIHTPQILQRSGIASAEYLESEGIELVEDLPGVGQNFQDHCATPITYSYDALFPAEADVTNNATYAAEAVAQFRERPARGPYTLAMGNSAAYVALQNVTPEWKRIVASIRAQIEDRSALQYLPAGATGAVIEGYLAQLEVLAQAFEHPEHPILEMPFHADPGIAFLLKPLSRGSVVLNATDHDSTPIVNYATGANPIDLDIMATYVDYVRHLYSADVWQAHGAVEVAPGADITKHDALIEYVKSTVIQSLMHPCCTATMLPREKGGVVDSSLSVYGISGLRVADCSIIPTIPASHTTTTAYAIGEKVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLA3</accession>
    <name>E3QLA3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ctf8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_06930</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the CTF8 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697356">
        <property type="protein sequence ID" value="EFQ31641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095661.1">
        <property type="nucleotide sequence ID" value="XM_008097470.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLA3"/>
    <dbReference type="STRING" id="645133.E3QLA3"/>
    <dbReference type="GeneID" id="24412295"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06930"/>
    <dbReference type="eggNOG" id="KOG4487">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090690_0_0_1"/>
    <dbReference type="OrthoDB" id="121932at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031390">
        <property type="term" value="C:Ctf18 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007064">
        <property type="term" value="P:mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018607">
        <property type="entry name" value="Ctf8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28605:SF1">
        <property type="entry name" value="CHROMOSOME TRANSMISSION FIDELITY FACTOR 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28605">
        <property type="entry name" value="CTF8, CHROMOSOME TRANSMISSION FIDELITY FACTOR 8 HOMOLOG (S. CEREVISIAE)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09696">
        <property type="entry name" value="Ctf8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ31641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="149" mass="16487" checksum="2AEC6102D1C31D41" modified="2011-01-11" version="1">MASVNIYPPRKAPPASDSPLPPLITTPSGLALLEMQGTINLPQVTFNEDNSQSGPEVPIGKVVFPDYRPDTQEDGSTAWMKRVFLYVGQHQRLHGEVKKLPKAMAIIRRRGQTTTGKDGEKEEELEVAEIVKYKIMFGNRPEPVSTEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLK1</accession>
    <name>E3QLK1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Vacuolar protein sorting-associated protein 74</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_06714</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Phosphatidylinositol-4-phosphate-binding protein that links Golgi membranes to the cytoskeleton and may participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus. May also bind to the coatomer to regulate Golgi membrane trafficking. May play a role in anterograde transport from the Golgi to the plasma membrane and regulate secretion. Mediates the cis and medial Golgi localization of mannosyltransferases through direct binding of their cytosolic domains. Involved in vacuolar protein sorting.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">Golgi stack membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GOLPH3/VPS74 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697357">
        <property type="protein sequence ID" value="EFQ31739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095759.1">
        <property type="nucleotide sequence ID" value="XM_008097568.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLK1"/>
    <dbReference type="STRING" id="645133.E3QLK1"/>
    <dbReference type="GeneID" id="24412079"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06714"/>
    <dbReference type="eggNOG" id="KOG3983">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036311_1_1_1"/>
    <dbReference type="OrthoDB" id="2189106at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032580">
        <property type="term" value="C:Golgi cisterna membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005797">
        <property type="term" value="C:Golgi medial cisterna"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019899">
        <property type="term" value="F:enzyme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070273">
        <property type="term" value="F:phosphatidylinositol-4-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030968">
        <property type="term" value="P:endoplasmic reticulum unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043001">
        <property type="term" value="P:Golgi to plasma membrane protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048194">
        <property type="term" value="P:Golgi vesicle budding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035269">
        <property type="term" value="P:protein O-linked glycosylation via mannose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045053">
        <property type="term" value="P:protein retention in Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060304">
        <property type="term" value="P:regulation of phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3630.10:FF:000002">
        <property type="entry name" value="Vacuolar sorting-associated 74 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3630.10">
        <property type="entry name" value="yeast vps74-n-term truncation variant domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008628">
        <property type="entry name" value="GPP34-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038261">
        <property type="entry name" value="GPP34-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12704:SF2">
        <property type="entry name" value="GOLGI PHOSPHOPROTEIN 3 HOMOLOG SAURON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12704">
        <property type="entry name" value="TRANS-GOLGI PROTEIN GMX33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05719">
        <property type="entry name" value="GPP34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="24"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00058727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00073084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ31739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="351" mass="38910" checksum="9C8E5392148B77B2" modified="2011-01-11" version="1">MSAPAGGLTRRRGGGATAGDGETSNGASRTNSTSNFNKDSAPETSYESGENGHKIAFDPRDISESAERSKQPKLTLMEEVLLLGLKDKQGYLSFWNDNISYALRGCIVIELAFRGRISMQKDASRRRFPLADRVIEVIDETLTGEVLLDEALKMMKQSEKMSVSSWIDLMSGETWNLMKIGYQLKQVRERLAKGLVDKGILRTEKRNFLLFDMATHPVADGGAKEEIRRRVRNVLTQRTVVLPPSQFLPENLEFRYVRTIAMVCAAYAANVLENALSTLGHEARERAFAQTDELLADYSQWPFGKKATGNGIGANLPQAIAEEISNGKDKELQLEVVAACLSVFTRLDSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLM3</accession>
    <name>E3QLM3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_06736</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697357">
        <property type="protein sequence ID" value="EFQ31761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095781.1">
        <property type="nucleotide sequence ID" value="XM_008097590.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLM3"/>
    <dbReference type="GeneID" id="24412101"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06736"/>
    <dbReference type="eggNOG" id="ENOG502SS12">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060776_0_0_1"/>
    <dbReference type="OrthoDB" id="4926491at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="344" mass="38780" checksum="174218DA5D80021D" modified="2011-01-11" version="1">MTTLPLKVKVAIRDHWTKEDSHLQQSLKSLQDVLGLEVDVNPEWQLLLAELDAGYTDRADAVIAVAGTVEAWCRAAAELLDDRKNEEWTETLLEKLKITWSRLRLFIEVSTGDDVSTSWSDDRGGFLVSLPRRQRITPVNLQPLFQAELKDCFADHRQLPPYTASPDADDWDDVDAIDTRVSRLSISGPDAAARHRRGPSVSSTATQPPPDFMPRADALPRPDDLLLKPPYHLMIYSRGAHEIEVQCSHSPTLKFLADYFKRWRRTNHQISSKPPAVEVRLHQCAFGMGASIDRLVLATEHKYGGAFILTPTVILSLVEGVLGYKPVYSDATTWTYRRDVELKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLQ1</accession>
    <name>E3QLQ1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">U3 small nucleolar RNA-associated protein 22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_06764</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
            <location evidence="1 5">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the NRAP family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697357">
        <property type="protein sequence ID" value="EFQ31789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095809.1">
        <property type="nucleotide sequence ID" value="XM_008097618.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLQ1"/>
    <dbReference type="STRING" id="645133.E3QLQ1"/>
    <dbReference type="GeneID" id="24412129"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06764"/>
    <dbReference type="eggNOG" id="KOG2054">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003502_1_0_1"/>
    <dbReference type="OrthoDB" id="10251401at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032545">
        <property type="term" value="C:CURI complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034456">
        <property type="term" value="C:UTP-C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006409">
        <property type="term" value="P:tRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005554">
        <property type="entry name" value="NOL6/Upt22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035082">
        <property type="entry name" value="Nrap_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035367">
        <property type="entry name" value="Nrap_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035368">
        <property type="entry name" value="Nrap_D3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035369">
        <property type="entry name" value="Nrap_D4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035370">
        <property type="entry name" value="Nrap_D5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035371">
        <property type="entry name" value="Nrap_D6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17972:SF0">
        <property type="entry name" value="NUCLEOLAR PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17972">
        <property type="entry name" value="NUCLEOLAR RNA-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03813">
        <property type="entry name" value="Nrap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17403">
        <property type="entry name" value="Nrap_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17404">
        <property type="entry name" value="Nrap_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17405">
        <property type="entry name" value="Nrap_D4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17406">
        <property type="entry name" value="Nrap_D5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17407">
        <property type="entry name" value="Nrap_D6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Nrap protein" evidence="6">
        <location>
            <begin position="130"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="Nrap protein" evidence="7">
        <location>
            <begin position="282"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="Nrap protein" evidence="8">
        <location>
            <begin position="430"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="domain" description="Nrap protein" evidence="9">
        <location>
            <begin position="595"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="domain" description="Nrap protein" evidence="10">
        <location>
            <begin position="787"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="domain" description="Nrap protein" evidence="11">
        <location>
            <begin position="945"/>
            <end position="1081"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF17406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ31789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1085" mass="122028" checksum="C0B6344B9ABA532D" modified="2011-01-11" version="1">MEQSPKRRKVFHQGDSRIAANIATASPFVLQTDELLKEVKVDYSEALDGADTLLHKIRNLIGGIESHGPIPIAEATRKFQKTHRIKIPYPEPKPAEDAPYKLSYEKPATYNVVGSYVSRTMVQAQANKGVDMIVQMPASLFQEKDHQNMRYFYRRAYYIAYIAANLRKELGESAGLEFEYLNGNALLPVLSVRPAATSNLGDESDGKKQTKAEYVIRVIPCAPEGVFPKTKLNPSFNSNRSGQTNAKDPNAATPFYNSTIKAEDTFITYLRVLTRAKTECRAFADACILGRIWLQQRGLGSSLSKGGFGHFEWATMMALLLQTGGRNGQPALSSALSSTELFKATVQFLASTEFSKKPFVFGTYKHGAEVIRENGPVMFDPDREVNILYKMSPWSASLLHFHACTTMEVLNDTLANQFEPTFITKADMPLQLYDAIFEIQNVDSNSKSNNPDRRGAVWDLSFKANALLKKALKERSQLIHFWSQDPASWPITGNQPRGLPNIQVGIVFDPANMGRLMEYGPSAELEKDAAKFRKFWGDKAELRRFQDGSILECVPWTNKTAAGICEEIVRYILQRHLSLGAGDLRFRDAELPSSLDISPLDKEAFEAARKAFGTLEQDIRGLEDIPLSIRQISPVVPELRFASFKPPFTLSQKTSPPAMDVNLYFEASSKWPENIVAIQETKIEFLLDIDRRLRAVNDSITTSLGRDNAARDIDNLAYLDIIYETGAAFRLRIYAELEETLLDRQAKNKTLSPQIRAEAEEALFNLHWRYKHLPLHTQTITTYCTRFTTLSTTIRLVKHWFNVHKLAGHVTEELIELLVLHVFLNPHPWKVPSSPMSGFLRTLLFLSHWDWRDEALVVDSSDDMAAEDRAIVSHHLEAWRAGDPNMNHAVLFVATPHDHLGLAYTRHGPSKLLATRMTRLAKAASRLVKERGIALDAAELFRPSLADYDVLLHLSSSALKRVVRDAASEVGTRHSLFKNLDERTGKVPLPLARHPATVLLRELEAAYEDALIFFHGAPDDVVIGAIWQPKLRSRQNFRVGLPYNFRQVKDAGDEEADPVEVNKPAILLEIARVGGDLIKRIELTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLY4</accession>
    <name>E3QLY4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07016</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095892.1">
        <property type="nucleotide sequence ID" value="XM_008097701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLY4"/>
    <dbReference type="GeneID" id="24412381"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07016"/>
    <dbReference type="eggNOG" id="ENOG502T4NH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1496076_0_0_1"/>
    <dbReference type="OrthoDB" id="4828976at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="180" mass="21003" checksum="DDBEA2D636DDE722" modified="2011-01-11" version="1">MPVGGMPNEPSRSSDSLPAVCSDKDWDNSPAGLARKQCRGLYELWDKRDSKYEDIRLQFARNRYRTRQYYEGQILLAQRKYEQGMGCCMLKLFFGRLLRRELKSICEKEQNAMNVLLKGETIERVAVTNKFADWEENYIIQCRKECARRYPATPFWYDEQEELSTSGDYEGSSVSAQSFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMF3</accession>
    <name>E3QMF3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">UDP-glucose 4-epimerase</fullName>
            <ecNumber evidence="11">5.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_07185</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>UDP-alpha-D-glucose = UDP-alpha-D-galactose</text>
            <dbReference type="Rhea" id="RHEA:22168"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:66914"/>
            <dbReference type="EC" id="5.1.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 11">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate metabolism; hexose metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">In the C-terminal section; belongs to the aldose epimerase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">In the N-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.2" evidence="11"/>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096061.1">
        <property type="nucleotide sequence ID" value="XM_008097870.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMF3"/>
    <dbReference type="STRING" id="645133.E3QMF3"/>
    <dbReference type="GeneID" id="24412550"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07185"/>
    <dbReference type="eggNOG" id="KOG1371">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_1_10_1"/>
    <dbReference type="OrthoDB" id="9402762at2759"/>
    <dbReference type="UniPathway" id="UPA00214"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003978">
        <property type="term" value="F:UDP-glucose 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05247">
        <property type="entry name" value="UDP_G4E_1_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005886">
        <property type="entry name" value="UDP_G4E"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01179">
        <property type="entry name" value="galE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007956">
        <property type="entry name" value="PRK10675.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43725">
        <property type="entry name" value="UDP-GLUCOSE 4-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43725:SF47">
        <property type="entry name" value="UDP-GLUCOSE 4-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0299">Galactose metabolism</keyword>
    <keyword evidence="7 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5 11" id="KW-0520">NAD</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="13">
        <location>
            <begin position="6"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="351"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU366046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ32041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="372" mass="40879" checksum="44D22415BE881DCD" modified="2011-01-11" version="1">MAVGTVLVTGGTGYIGSFTSLTLLQNGYDVVIVDSLYNSSKVAVDRIELLSGKRPHFYQVDITDKAGLDAVFKKHPEIDSVIHFAALKAVGESGEIPLEYYRVNVGGTVALLQAMTDNNVPNIVFSSSATVYGDATRFENMIPIPEHCPIGPTNTYGHTKAFVEQIITDHIQAERNKLKKAEKPFEHFNGALLRYFNPCGAHPSGLMGEDPQGVPYNLLPLLGKVATGEREKLLVFGNDYTSRDGTAIRDYIHVVDLARGHLAALNYLRENKPGVKAWNLGSGRGSTVFEMIKAFSHVVGRDLPYEVVPRRQGDVLDLTANPSLANKELSWKTEKTLEEACEDLWRWVSNNPKGYRQDPPPELLANAKPTSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QN23</accession>
    <name>E3QN23_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_07405</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697361">
        <property type="protein sequence ID" value="EFQ32261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096281.1">
        <property type="nucleotide sequence ID" value="XM_008098090.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QN23"/>
    <dbReference type="GeneID" id="24412770"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07405"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_13_1"/>
    <dbReference type="OrthoDB" id="6133115at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000217">
        <property type="entry name" value="MFS lactose permease, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF70">
        <property type="entry name" value="MONOSACCHARIDE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G14540)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="94"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="155"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="378"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="411"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="447"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="477"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="61"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="9"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ32261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="541" mass="59625" checksum="29BBA00FD80E8ECA" modified="2011-01-11" version="1">MATLQESKSNAEVEHDGTPFDEKAPAGEVTEINAASVALAAALAERPPNIWSPNMIKLYCILAIGYLVSTMNGFDSSLMGSQNAMPQYQKTFGLDGAGSTTGIVFMIYQVGQVVSFPFCSPLADGYGRRFCIFVGCFIVLIGTAIQTPANTLGQFIGGRFVLGFGASLASAAGPAYIVELAHPKYRGTMAGAYNTFWWLGNILAGWTTYGTNEHLETSWAWRIPTLVQAGMPAVVMCFIMFFPESPRWLISHDRGEEALAILAKYHGDGDASSPVVQLQYQEIVEDNRLTKDENPWWDMRELFHTRAARYRLYMMIAMAFFGQWSGNNVVSYFMPEMFKQAGITSDSTQLLLTAINPIFCLIAAIYGATLLDKLGRRFMMLAGLAGSLVAYIMLTAFTAETPNNQNLSYGVIVSIYLFGIVFSWGFTPLQTLYAVECMENRTRAKGSALSFLFLNIAIIINTYGISVGIQKIGYKLYIVYIVWICVEIAIIYFFFVETAGKTLEELKTIFEAPNPRKESTKKTKVAVDGAGNVLDVGETYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNH5</accession>
    <name>E3QNH5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_07732</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the chloroperoxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697362">
        <property type="protein sequence ID" value="EFQ32462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096482.1">
        <property type="nucleotide sequence ID" value="XM_008098291.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNH5"/>
    <dbReference type="STRING" id="645133.E3QNH5"/>
    <dbReference type="GeneID" id="24413097"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07732"/>
    <dbReference type="eggNOG" id="ENOG502S6CG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029871_3_1_1"/>
    <dbReference type="OrthoDB" id="407298at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.489.10">
        <property type="entry name" value="Chloroperoxidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000028">
        <property type="entry name" value="Chloroperoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036851">
        <property type="entry name" value="Chloroperoxidase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577:SF16">
        <property type="entry name" value="HEME HALOPEROXIDASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577">
        <property type="entry name" value="STERIGMATOCYSTIN BIOSYNTHESIS PEROXIDASE STCC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01328">
        <property type="entry name" value="Peroxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47571">
        <property type="entry name" value="Cloroperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51405">
        <property type="entry name" value="HEME_HALOPEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178657" evidence="8">
        <location>
            <begin position="20"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="Heme haloperoxidase family profile" evidence="9">
        <location>
            <begin position="65"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ32462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="438" mass="47512" checksum="AB96C0DEA4D94068" modified="2011-01-11" version="1">MKSHYLLSLLPYLGSGVVAFPAYLNEALKNGADSELSEQLAGVFHETHEKRLLFDPMTTPIDVAGEHRFIPPNFEKGDQRGPCPGLNALANHGYISRDGVTGIAEVTGAINRVFGMGIDIAAILGILGTVFVGNPLSVNPGFSIGDVSRSSNNILDNVFGLLGAPRGLNGSHNIIEGDASLTRADLYMTGDASTMVMDQFQALYDMSPGEGDYNMDLFGERSSIRFRESIETNPNFYYGPFTGMIARNAAYFFACRMFSNYSSENPDGVLNKETLKSFFAVQGEEGNLTYNRGWERIPENWYRMPVDYTLVHLNLDLVALILKHPELGSIGGNMGEINSFAGVNLGDLTGGVLSLSKLLEGNNLLCFVFEILKTVSPNSLSTIFTIIEKPLSMVTDALGTALLNLSCPAFKDMQVGGHSLDEGLKAQYPGARMSDNVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNT3</accession>
    <name>E3QNT3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_07710</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697362">
        <property type="protein sequence ID" value="EFQ32440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096460.1">
        <property type="nucleotide sequence ID" value="XM_008098269.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNT3"/>
    <dbReference type="STRING" id="645133.E3QNT3"/>
    <dbReference type="GeneID" id="24413075"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07710"/>
    <dbReference type="eggNOG" id="ENOG502SUMD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_735814_0_0_1"/>
    <dbReference type="OrthoDB" id="4770059at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549:SF26">
        <property type="entry name" value="AXIAL BUDDING PATTERN PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="234"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="265"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="265"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="301"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="362"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ32440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="371" mass="38914" checksum="049437A4C5F48C4A" modified="2011-01-11" version="1">MTATSDPNPMTTKRGAAPLTTVFTTPDFCNSKYWTDTITPPLSSVVCMPPSWHQLFDYSWGFYSPGICPTGYTEGCAFPTSLAFTSSNGDMGLGGPVIAGETPRLCCPTGYTCYTGESAYSKCISTKPTTTFYDINNQLTSQLALVYAIQVRWQESDLPFLQTNPTVPGATYTAPASAGSGASATARAAATATGSASTATGSTTAAVSAIGSSSGDDGSSRGGDDGGISVGTTVGIAVGSVLGTLALALLGFMFWWRRRRRQEAGAREDDHHGGDVKSHTLTLPHEGPSGRTSLLYAMSPTTTGRPGTGTTVGDAPPPHSPAPTQLDSTNVMEMGTTERPQELPEDNEVYEMEGDMPGPPLYREKEGWPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3QP90</accession>
    <name>E3QP90_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_07822</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697364">
        <property type="protein sequence ID" value="EFQ32678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096698.1">
        <property type="nucleotide sequence ID" value="XM_008098507.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QP90"/>
    <dbReference type="STRING" id="645133.E3QP90"/>
    <dbReference type="GeneID" id="24413187"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07822"/>
    <dbReference type="eggNOG" id="KOG1721">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053582_0_0_1"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000060">
        <property type="entry name" value="zinc finger protein 436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000176">
        <property type="entry name" value="zinc finger protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050331">
        <property type="entry name" value="Zinc_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515:SF49">
        <property type="entry name" value="GASTRULA ZINC FINGER PROTEIN XLCGF49.1-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515">
        <property type="entry name" value="PR DOMAIN ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="261"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="289"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="53"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="75"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="116"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ32678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="321" mass="35051" checksum="D01B4E010675F343" modified="2011-01-11" version="1">MASALISNPYAAQQSAHYGYVQPPQPPPSPPMDETSKCSLPSISNLLGLADQGSPTSETHPQIPQQGTDRADYQQHGNSYTSSRRLTLDSACSQKSETRPNSSHYGRGGLPPSPPMSSDASFDGYNSPSTRSVSQLSVVSQPQSNYYYESTPPLEADAHRHMAPMVSRVPVQASYAQQPFQHAYMPAHNPMAASYYPSMQPTPPPQAQMSGIYYQRPLPQQFPPMAPVPVGLGPAGSNPWQHHHYISPSSAASFPQSQDRYICQTCNKAFSRPSSLRIHSHSHTGEKPFKCPHAGCGKAFSVRSNMKRHERGCHNFESGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQ75</accession>
    <name>E3QQ75_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal L28 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_08157</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL28 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697366">
        <property type="protein sequence ID" value="EFQ33013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097033.1">
        <property type="nucleotide sequence ID" value="XM_008098842.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQ75"/>
    <dbReference type="STRING" id="645133.E3QQ75"/>
    <dbReference type="GeneID" id="24413522"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08157"/>
    <dbReference type="eggNOG" id="KOG3278">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064548_0_1_1"/>
    <dbReference type="OrthoDB" id="361870at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.40">
        <property type="entry name" value="Ribosomal protein L28/L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026569">
        <property type="entry name" value="Ribosomal_bL28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="Ribosomal_bL28/bL31-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037147">
        <property type="entry name" value="Ribosomal_bL28_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13528">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L28, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13528:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL28M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00830">
        <property type="entry name" value="Ribosomal_L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="L28p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178726" evidence="4">
        <location>
            <begin position="27"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ33013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="256" mass="28571" checksum="336F023980D61939" modified="2011-01-11" version="1">MRFITPRPGSSLLVSLQNLTLTTTAAAPSARAFSTSSPLATKTINLQKIPAAPVPPYPYGPRLLYKQSNNGLYGAARIRHGHNVSEKHGQVTPRTWRPNVHRKRLWSEALGAWVRARLTTRVLRTVRREGGIDAYVTKAKPARVRELGPGGWRLRWLVANSPAFRARYAAEREALGVRAPMPEDQTDLVYYMIDASTGNRLSATSRQTLERRASQMIAEEFAIGDDAELFEPGALYEDDDFHAQGIKEPPVEEKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>E3QQP9</accession>
    <name>E3QQP9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_08331</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697368">
        <property type="protein sequence ID" value="EFQ33187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097207.1">
        <property type="nucleotide sequence ID" value="XM_008099016.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QQP9"/>
    <dbReference type="STRING" id="645133.E3QQP9"/>
    <dbReference type="GeneID" id="24413696"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08331"/>
    <dbReference type="eggNOG" id="ENOG502QSDU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004835_4_0_1"/>
    <dbReference type="OrthoDB" id="4685598at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.240.10:FF:000008">
        <property type="entry name" value="C6 zinc finger domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053181">
        <property type="entry name" value="EcdB-like_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785:SF2">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="120"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="47"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ33187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="692" mass="76612" checksum="0AF90BC479BD991A" modified="2011-01-11" version="1">MSPSSTGDSPCSATGNAGRPFHVPSRETFNIEVPSPSMTNGIHPLKSPTSLKTQRTPSFSRDGILGSAQKARNMSHSSENRPEALANGMDKAPSDEGSNPLKRRNTDAGIDYPRRRATIACEVCRSRKSRCDGTKPKCKLCTELGAECVYREPGIKLDAGDKLILERLNRIESLLQMNMVAGQGNGIAINQESPSMSNGSGLNGESIMGVSGSGNIVSVIPNGGLGTWNNPTNISTMPKMHTNAALHLLQWPLIRDLVSRPYDPQVLLQLEMAREPLHSLTKTPCVDLSNTTAYIEAYFERVNVWYACVNPYTWRSHYRTALSNGFREGAESCIVLLVLALGQASLRGSISRIVPGEDAPGLQYFTAAWALLPGMMTSNNVLAAQCHLLASAYLFYLVRPLEAWNLLCTTSTKLQLLLMSPNRVPPNQRELTERIYWNSLLFESDLLAELDLPHSGVVQFEENVGLPGGFEGEEQEAIGRDDLWYFLAEIALRRLLNRVSQLIYSKDSMASTTSLEPVVAELDFQLTQWYESLPMPLQFPFTRNLLSDPVQTVLRLRFFACRTIIYRPYILAVLDNEQAVLDPAVRDSCHKCLEASIRQLEHISQHHAGHMPYLWQGALSIVSQTLLVMGATMSPSLSSILLTLVPHRETIDQIINDVVMEIERYSTLAPSLSLAAEIIKEAEVRRRAYLSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QR64</accession>
    <name>E3QR64_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">WD40 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08496</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697369">
        <property type="protein sequence ID" value="EFQ33352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097372.1">
        <property type="nucleotide sequence ID" value="XM_008099181.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QR64"/>
    <dbReference type="STRING" id="645133.E3QR64"/>
    <dbReference type="GeneID" id="24413861"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08496"/>
    <dbReference type="eggNOG" id="KOG4497">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024072_2_0_1"/>
    <dbReference type="OrthoDB" id="308690at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990811">
        <property type="term" value="C:MWP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990810">
        <property type="term" value="P:microtubule anchoring at mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052778">
        <property type="entry name" value="Centrosome-WD_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16220">
        <property type="entry name" value="WD REPEAT PROTEIN 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16220:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN WRAP73"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="478"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ33352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="516" mass="56193" checksum="44D51A12EB31C8AE" modified="2011-01-11" version="1">MHFSRVFKSSPHCASSPDGNLIATLSPTSITVRSVETLETIHSVKVSPKLGPAYALRWSPCSRRILACFAEEIRVYAASAPGYHAVIRNPATPNLKPTFVQFGSSDAEVFMCSSYGLKFSIFDLAASSTVEITNPKFYQAAAASRGFALRPDSSHLAILTRVAGKDIVSIHHPKTRGVLRSWQPDTADAQALTWTPDGRWLVIWESAAQGHKILFYTPDGHLFKTWSGPSSIEAEDQHYELGAGVKACQLSPDGARLAVCDHTRSVRVLDTNTVAESMRLDHPVAITPTETIQIWQEQIGTGQPGPQRSFSRATQAVSAPGRTNNGSTDAKPARTLALFDASSSLLATTLEDWPSTVWVWDLASSELRAVLLFHGNVSAFCWHPTHREVLVVTCEGDSYAGLAFVWDPLSDGPKTVDFGGQLPEAKVLGKPQVSWLDWTGDAAVLLLGDNKYRIMACLADPEDSVAPWQDAQRGDLTMTTGRDETQLSTPALDGFDEDLSGLDMSEVDDTFSFKRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSC8</accession>
    <name>E3QSC8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Amino acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_08899</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697373">
        <property type="protein sequence ID" value="EFQ33755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097775.1">
        <property type="nucleotide sequence ID" value="XM_008099584.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSC8"/>
    <dbReference type="STRING" id="645133.E3QSC8"/>
    <dbReference type="GeneID" id="24414264"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08899"/>
    <dbReference type="eggNOG" id="KOG1286">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007946_12_1_1"/>
    <dbReference type="OrthoDB" id="3900342at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000006">
        <property type="entry name" value="General amino acid permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF36">
        <property type="entry name" value="PROLINE-SPECIFIC PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="82"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="164"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="198"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="287"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="340"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="385"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="414"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="458"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="487"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="8">
        <location>
            <begin position="54"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ33755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="555" mass="61133" checksum="061B851FF61EA5B3" modified="2011-01-11" version="1">MDKDERGGGPLTDVESKHAGETFPRDVNFATLSGDANDLVNQHDQLQRGLKSRHIQFLALGGAIGTGLFVGSGSILSTVGPAPLFMGYLSMMMVVWNIMNNLGEMATYLPLKGISIPYFVERFVEPSLAFAAGWNYWYAYAMLVGAEASAGAILLDYWQSPVPPAVWITIILLVTLALNIFAVEIFGEAEFWFASIKLITILGLILVSFVIILGGAPDEGRIGFLYWYDPGAIKPYLVGGDTGRFLAYWTGFVRAGFAFITSPELIALAAGETVAPRRNIPKAASRFVWRLAIFYGLGSLMIGAITPSDDPRLLTPTSNAAASPWVIGIQRAGIGGLNHVINAAILTSAWSAGNAFLYSGSRILYSLALNKQAPHFFTRTTKRGVPYTAVLGTWSISLLSYLTVSSGTSTVFTWFMNISTISGFIAWIVVMVTYLRFRKAMIYHNMMHRLPFRTPLQPYFTWFILGLLVILTITNGFQVFFPGHWSVSDFLAAYITLPIFLVLYVGHKVWFRTPLARSVADVDVTTGVAEMEAMAELDEEPIPKNMLQKAWFWIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSK6</accession>
    <name>E3QSK6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ceramidase</fullName>
            <ecNumber evidence="1">3.5.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_08988</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.1.23" evidence="1"/>
    <dbReference type="EMBL" id="GG697374">
        <property type="protein sequence ID" value="EFQ33844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097864.1">
        <property type="nucleotide sequence ID" value="XM_008099673.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSK6"/>
    <dbReference type="STRING" id="645133.E3QSK6"/>
    <dbReference type="GeneID" id="24414353"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08988"/>
    <dbReference type="eggNOG" id="ENOG502QVBG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051035_0_0_1"/>
    <dbReference type="OrthoDB" id="5273684at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017040">
        <property type="term" value="F:N-acylsphingosine amidohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28583">
        <property type="entry name" value="ACID AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28583:SF1">
        <property type="entry name" value="ACID CERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ33844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="393" mass="43732" checksum="7C7FF08403B999C6" modified="2011-01-11" version="1">MRSVSPLFDEVIEWLVGRKLASVIKLASRHALRRVFDKEQTKEIRSIASVVKIRTHLLISLNLFLDLMLGCTSGAALVRPEPGDRDGQDTKDRLMHFRTLEWGMDALRDLLVIVEFVDSSKGDTDEVVARSVSYAGFVGCLTGVRKDLSVSLNFRPTHDCTTASLRRHQLSVLLGRREAVPSILRRILLDHDIPSNSLKVPVYNGPHINNSEQRPLSITGVAKKFISMPTSPCYITLCNGFKVVSVLKDLCTGKAKTSSLFQVQCNHDPDHGTCCGPKANNSPPEATQAMIIGEDDWLGESEGRKRVLEEKWLQHMAAVTKEAGEELKPCINSLCLDADTRADLGINIKVRGVDEAILQQWINTYPTTNECTHFACIMDPAYGTIRWIARGRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QSW5</accession>
    <name>E3QSW5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_09097</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697375">
        <property type="protein sequence ID" value="EFQ33953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097973.1">
        <property type="nucleotide sequence ID" value="XM_008099782.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QSW5"/>
    <dbReference type="STRING" id="645133.E3QSW5"/>
    <dbReference type="GeneID" id="24414462"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09097"/>
    <dbReference type="eggNOG" id="ENOG502S61U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_18_0_1"/>
    <dbReference type="OrthoDB" id="9975416at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050832">
        <property type="entry name" value="Bact_Acetyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43877:SF2">
        <property type="entry name" value="AMINOALKYLPHOSPHONATE N-ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43877">
        <property type="entry name" value="AMINOALKYLPHOSPHONATE N-ACETYLTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="15"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ33953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="185" mass="20442" checksum="BFBB3893B743CEF0" modified="2011-01-11" version="1">MARSMENQEIKRPATAIRPAALADATAISELGAHVFTVTFGHSVEPHELQAFLDESYSLKATMKDLEDPKKDTILATDSTGDILGFGMLTRGTSEPCLSHLDGLVELQRIYMHPKAHGTGAGKLLANKLEEMAREQGFKYIWLGVWQENHRAKKAYEKWGYKACGTHGFAVGPVVQTDDIMVKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QT00</accession>
    <name>E3QT00_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Beta-eliminating lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_09132</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the threonine aldolase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697375">
        <property type="protein sequence ID" value="EFQ33988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098008.1">
        <property type="nucleotide sequence ID" value="XM_008099817.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QT00"/>
    <dbReference type="STRING" id="645133.E3QT00"/>
    <dbReference type="GeneID" id="24414497"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09132"/>
    <dbReference type="eggNOG" id="KOG1368">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049619_1_0_1"/>
    <dbReference type="OrthoDB" id="10261951at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001597">
        <property type="entry name" value="ArAA_b-elim_lyase/Thr_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097">
        <property type="entry name" value="L-THREONINE ALDOLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097:SF5">
        <property type="entry name" value="LOW SPECIFICITY L-THREONINE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01212">
        <property type="entry name" value="Beta_elim_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aromatic amino acid beta-eliminating lyase/threonine aldolase" evidence="4">
        <location>
            <begin position="39"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ33988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="355" mass="38862" checksum="E352FB1F96DDE92E" modified="2011-01-11" version="1">MPSQTLVPNSAPRYSFLDDYSEGAHPALLKAILSSNTSQEAGYGGDAYCALARQRIRRHLGREDVGVFFVPSGTSANAISIAACLRPHEAVIAASSGHIVTRETGAVEASGHKIINVAPVDGKLTPQSIQRAMDDNWHFPHMAKPRLVYVSNATEIGTLYTRAELAAIKHVCERNQLLLFLDGARIGTALVSKANDMTLADVLELTDIFWIGGTKNGALLGEAVVVKDARLATEYEFYMKQHGSLLAKSRIMGVQFAELFKDDLYFDLARQANLCAETLSSGVAAAGFSVYAVTETNQVFAVLPLGLIQALQEHFTFYVWEKRADDEAVVRLLTTWATEITEVDKFIRLVQGWNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>E3QT13</accession>
    <name>E3QT13_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_09145</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697375">
        <property type="protein sequence ID" value="EFQ34001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098021.1">
        <property type="nucleotide sequence ID" value="XM_008099830.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QT13"/>
    <dbReference type="GeneID" id="24414510"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09145"/>
    <dbReference type="HOGENOM" id="CLU_3124938_0_0_1"/>
    <dbReference type="OrthoDB" id="10679456at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ34001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="50" mass="5410" checksum="42B0C7863C3CED42" modified="2011-01-11" version="1">MHHNMVFKVEMTNKSDDAPNLVAARIADKAYSQNRFLGADGSAVSKRGCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTG0</accession>
    <name>E3QTG0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycosyl hydrolase family 31</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_09292</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697377">
        <property type="protein sequence ID" value="EFQ34148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098168.1">
        <property type="nucleotide sequence ID" value="XM_008099977.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTG0"/>
    <dbReference type="STRING" id="645133.E3QTG0"/>
    <dbReference type="GeneID" id="24414657"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09292"/>
    <dbReference type="eggNOG" id="KOG1066">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000631_7_3_1"/>
    <dbReference type="OrthoDB" id="10070917at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14752">
        <property type="entry name" value="GH31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06591">
        <property type="entry name" value="GH31_xylosidase_XylS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1760">
        <property type="entry name" value="glycosyl hydrolase (family 31)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025887">
        <property type="entry name" value="Glyco_hydro_31_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051816">
        <property type="entry name" value="Glycosyl_Hydrolase_31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43863">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G03140)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43863:SF2">
        <property type="entry name" value="MALTASE-GLUCOAMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13802">
        <property type="entry name" value="Gal_mutarotas_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 31 N-terminal" evidence="4">
        <location>
            <begin position="20"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="3">
        <location>
            <begin position="232"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="5">
        <location>
            <begin position="577"/>
            <end position="664"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ34148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="665" mass="76584" checksum="A652BE302479DBFF" modified="2011-01-11" version="1">MGLQEKDGKLVFTYDAEQLWVQAWGPNAFRVRASKAREMPTEDWALLNPNRTEVNIAIDANAATITNGKIKASITRGGKLLMWNSKGELLLEEYSRHRRDVLDPKCSALDVEAREFLAIVNSNDYHLTARFESINADEKIFGMGQYQQPFLDLKGHDLELAHRNSQASVPFAVSSLGYGFLWNNPSVGRAVLGRNIMSFEAKSTRALDYWIVAGDTPAEIVEAYADVTGKVPMMPAYGLGFWQCKLRYQTQEELLEVAREYRRRKLPIDLIVIDFFHWPLQGEWKFDATYWPDPEAMIKELQELKIELMVSIWPTVDQKSENWDEMVEKGYLIQSDRGIRIAMNFQGDTTHFDATNPGARDYVWKKAKKNYYDKGIRVFWLDEAEPEYTVYDFDTYRYHLGSNVSIGNIYPVEYARAFYEGMKAEGQEEIVNLIRCAWAGSQRYGALVWSGDIASSWGSLRNQVAAGLHMGLCGLPWWTTDIGGFHGGDPRDESFRELFVRWFQWGAFCPVFRLHGCREPEQPQHGTTGGATCRSGAPNEVWSYGPEVYEICKRYMFLREELREYIRSLMKEAHERGTPVMRTLFYVFPSDKETWNIGQQYMFGDKYLVCPVLEAGKTRINVYLPVLEGDGKWKPLLEGKSNTYEGGRWIDIEAPLEWMPVFQRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QU73</accession>
    <name>E3QU73_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09555</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697380">
        <property type="protein sequence ID" value="EFQ34411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098431.1">
        <property type="nucleotide sequence ID" value="XM_008100240.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QU73"/>
    <dbReference type="GeneID" id="24414920"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09555"/>
    <dbReference type="eggNOG" id="ENOG502SRF0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033273_0_0_1"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053083">
        <property type="entry name" value="TF_kinase-domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44305">
        <property type="entry name" value="SI:DKEY-192D15.2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44305:SF24">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE C03B1.5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="439" mass="49902" checksum="5565278B3B6ED6BD" modified="2011-01-11" version="1">MEDPDHPQPSFQLVKRVQDEIWLARRVAQNPSYADGEEFIARKVDDFDEYYEAGKYSMSFTTKRQRQVKGLMDLLYDCNLGRNVSHILNHENIISLAGYLRQEPVHPRVDATEDYLVWDICDAGTLENLLANPEADADPGCFLPESLCWHVLVSIMRALVWLHDGYRQEVTWASGERSWKKTDAEWMPILHRDISAKAVFFQHPRGRETYGVCKLGKFGNAFISGVPARRDGAPDGEKPLPHSIGFPIAPKKEHMGLADMTKQWREYLGTGRNGKRLYTLSDEHWALGAVLFRMMTGRPLPSLDGCGACRCIHIRRCAKVNCVYNGEHSGRECEHEAFRGCHCPTPCTAETDVHMDETLHRTRYSSYLVLAARMLLNYDLEAPAVGTQGLAAEIEVLYRRWRSETEDGQEYVDVEDDLGYRFLVLNNAATVGKAEEMDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUC4</accession>
    <name>E3QUC4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_09606</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697380">
        <property type="protein sequence ID" value="EFQ34462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098482.1">
        <property type="nucleotide sequence ID" value="XM_008100291.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUC4"/>
    <dbReference type="GeneID" id="24414971"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09606"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_3_1"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000090">
        <property type="entry name" value="MFS sugar transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF72">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="265"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="299"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="335"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="368"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="401"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="430"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="15"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="487"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="488"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ34462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="510" mass="57056" checksum="0196BC7BC8DEA9C0" modified="2011-01-11" version="1">MFLSLGRGKSLQFGVTICCLIAFVLFGYDQGVFGGILQMEDWLNQFDHPSDSETGIIVSCYNLGCLFGCVLNFAFGEKLGRRKTIWTAMALVIVGATLQATAYTVPHLVIGRIVTGFGTGMKTSTVPMYQSELCDRKYRGRLVSAETLFVGVGIVFAYWFDFGMSYVGGPIAWRLPLAFQIVFALVVIVLVFALPESPRWLFKHGREQEAVHVLCDVFDKEPTDEYIRAEVLAIHHAIELDAIEDKSSSWISIFRNDRLKTGHRVLLAWGAQFMNQIGGINLVVYYIPSVLVQNVGMTAHLAQIIGGCVQMMFMFGSILPALALDRMGRRKTMMWGSAGLGFCMFMISVLLSRVGLANGQVCASASVAFFFLYNLIFGMGMNCVPWVVVPEILPLHARTRGTAVGISSNWLWNFFVVMITPVIINRLQWKAYLIFMVTNFVFVPVIYYFYPETSNFGLEEIDEFFTSGRNPVKVAKEMTKAMRISGVRPEKDLNKTSTSEEKAKVDVEHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUG6</accession>
    <name>E3QUG6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09648</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697381">
        <property type="protein sequence ID" value="EFQ34504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098524.1">
        <property type="nucleotide sequence ID" value="XM_008100333.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUG6"/>
    <dbReference type="STRING" id="645133.E3QUG6"/>
    <dbReference type="GeneID" id="24415013"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09648"/>
    <dbReference type="eggNOG" id="ENOG502T4M4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_874376_0_0_1"/>
    <dbReference type="OrthoDB" id="4837392at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="368" mass="41959" checksum="9EF0B95C0BD40B48" modified="2011-01-11" version="1">MAPNITLPAIPEEEEDWEDASSSSDDTCNENNENSQDSERLSPPPGLLFPHEMARPPSPPIHAPRLRLLYHSQTWDTQVYMLKDGKVLKERASFPSLSQGYFGAVEMNEKLRHWFRVLPQQLGEMLGSDHPYLSRFAIAMAPRQYMLMRGSGNSDHLPDQLVEPFPEMKGRLVMERVRPVKPAVMRVLIDKIISPALHRRAIANPENYNLHPKAWLGFEQPPAVRDMLRNHPNLSTRPAYLNELVRFIGRRGVLELAREMGTALAVIHYDLNKDAHDIRFRIGYNPALDKAKLWVCGLGCMRDLKKNERFYPRPGVGHGVFDAFWAAYVLASEGILQWRMENAVEGSDKDAGLRSLMIKVLLEHLDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUJ1</accession>
    <name>E3QUJ1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CorA-like Mg2+ transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_09673</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697381">
        <property type="protein sequence ID" value="EFQ34529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098549.1">
        <property type="nucleotide sequence ID" value="XM_008100358.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUJ1"/>
    <dbReference type="STRING" id="645133.E3QUJ1"/>
    <dbReference type="GeneID" id="24415038"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09673"/>
    <dbReference type="eggNOG" id="ENOG502RIZT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_547462_0_0_1"/>
    <dbReference type="OrthoDB" id="10071171at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="366"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="398"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="315"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ34529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="498" mass="56641" checksum="4B41DF15500D3F89" modified="2011-01-11" version="1">MIGNAGAEVSGLAPPSVDLDRPEPPEKVPRPRHVHLSARHRYDGAFSWPPRFFDDHQGGFSRSWENSPYIDLLSYARELEGNDISIFLRTEENWAPDQQRVDSVLDITREATIQNLLDRDERAQKEKIALLIDGNASGPGPHLRDFLGGLTAQALYDELSKKRYSEDGDDSVVDTDRRLIYVANLDAWGIMALVGTSPESLFRVLGDFVLNYTCANPSIGVSFSIRRHENFIRRVRTPTLDQVPPIPKQRKILEEFDELENGLRYFKEVLDELAQVLQENVRSGELFMKTDVLYFRNYDEPSDDASICFPYLAQIRKTFTNLEQLRQRLGDMQQKCKEMVEEVASVRKMHRQQLNILTPVHYSPTVLAWITILTFPLIITAALFSCDDIFIFKRSWKSFLLVWLVITVIVLAIAAIRVWLFQSQKTPDNEIEGSCNPLNALDSQEKTAADQITQEVPRCATLFTGVIGVFQKRGVGKAVAENPRIRDQIIALETCGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QV42</accession>
    <name>E3QV42_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial</fullName>
            <ecNumber evidence="16">1.3.8.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="19">2-methyl branched chain acyl-CoA dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="18">2-methylbutyryl-coenzyme A dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="31" type="ORF">GLRG_09876</name>
    </gene>
    <organism evidence="32">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="32" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="32">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="22">
            <text>(2R)-2-methylbutanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = ethylacryloyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:65296"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:156439"/>
            <dbReference type="ChEBI" id="CHEBI:156440"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="22">
            <dbReference type="Rhea" id="RHEA:65297"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="25">
            <text>(2S)-2-methylbutanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-2-methylbut-2-enoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:48256"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57337"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:88166"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="25">
            <dbReference type="Rhea" id="RHEA:48257"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>2-methylbutanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-2-methylbut-2-enoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:43780"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57336"/>
            <dbReference type="ChEBI" id="CHEBI:57337"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="EC" id="1.3.8.5"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="20">
            <dbReference type="Rhea" id="RHEA:43781"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="26">
            <text>2-methylpropanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = 2-methylpropenoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:44180"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57338"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:62500"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="26">
            <dbReference type="Rhea" id="RHEA:44181"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="23">
            <text>butanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:24004"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57332"/>
            <dbReference type="ChEBI" id="CHEBI:57371"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="23">
            <dbReference type="Rhea" id="RHEA:24005"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="24">
            <text>hexanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-hexenoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:43464"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:62077"/>
            <dbReference type="ChEBI" id="CHEBI:62620"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="24">
            <dbReference type="Rhea" id="RHEA:43465"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>valproyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-2-propylpent-2-enoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:65344"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:156457"/>
            <dbReference type="ChEBI" id="CHEBI:156458"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="21">
            <dbReference type="Rhea" id="RHEA:65345"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 27">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="15">Amino-acid degradation; L-isoleucine degradation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism; mitochondrial fatty acid beta-oxidation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 27">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.3.8.5" evidence="16"/>
    <dbReference type="EMBL" id="GG697383">
        <property type="protein sequence ID" value="EFQ34732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098752.1">
        <property type="nucleotide sequence ID" value="XM_008100561.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QV42"/>
    <dbReference type="STRING" id="645133.E3QV42"/>
    <dbReference type="GeneID" id="24415241"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09876"/>
    <dbReference type="eggNOG" id="KOG0139">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_0_0_1"/>
    <dbReference type="OrthoDB" id="10262177at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003853">
        <property type="term" value="F:short-chain 2-methyl fatty acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046395">
        <property type="term" value="P:carboxylic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01158">
        <property type="entry name" value="SCAD_SBCAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.540.10:FF:000012">
        <property type="entry name" value="Acyl-CoA dehydrogenase short/branched chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.10:FF:000002">
        <property type="entry name" value="Acyl-CoA dehydrogenase short/branched chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000001">
        <property type="entry name" value="Acyl-CoA dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884:SF1">
        <property type="entry name" value="SHORT_BRANCHED CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0007">Acetylation</keyword>
    <keyword evidence="8 27" id="KW-0274">FAD</keyword>
    <keyword evidence="9" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="7 27" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="14" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12 27" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="32" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="30">
        <location>
            <begin position="70"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="29">
        <location>
            <begin position="184"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="28">
        <location>
            <begin position="291"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00037895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00039036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00039850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00041537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00042821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00048307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00048592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00049096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00049192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="ARBA" id="ARBA00049552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="ARBA" id="ARBA00051903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="27">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="28">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="29">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="30">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="31">
        <source>
            <dbReference type="EMBL" id="EFQ34732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="32">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="446" mass="48600" checksum="4FD9063D69A77164" modified="2011-01-11" version="1">MSSFARAIRPAMRGSRGVAALAKGRTCTPTRTFLPLQQAARPLSTTQRRRNADHLDITDIPPTPITHLSEVEAAMQETVNKFANDVIAPKVREMDEAEDMDPAIVEQLFEQGLMGVEIPEEYGGAGMNFTSAIIGIEELARVDPSVSVLVDVHNTLVNTAIIKWGSSQLKQRFLPKLATNTVGSFCLSEPVSGSDAFALATKATKTENGYKINGSKMWITNSKEADFFIVFANLDPAKGYKGITAFIVEKNTKGFSIAKKEKKLGIKASSTCVINFDDVEIPRENLLGEEGSGYKYAIGLLNEGRIGIAAQMTGLALGSWENAVKYVWNDRKQFGQLVGEFQGMQHQIAQSYTEIAAARALVYNAARKKEAGDNFVMDAAMAKLYASQVAGRVSGLAIEWMGGMGFVRDGPAEKFWRDSKIGAIYEGTSNIQLNTIAKLLQKDYTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVP1</accession>
    <name>E3QVP1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">WSC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_10073</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697385">
        <property type="protein sequence ID" value="EFQ34929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098949.1">
        <property type="nucleotide sequence ID" value="XM_008100758.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVP1"/>
    <dbReference type="STRING" id="645133.E3QVP1"/>
    <dbReference type="GeneID" id="24415438"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10073"/>
    <dbReference type="eggNOG" id="ENOG502QQEE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013323_0_0_1"/>
    <dbReference type="OrthoDB" id="2019572at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00321">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178929" evidence="2">
        <location>
            <begin position="26"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="3">
        <location>
            <begin position="306"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="631"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="186"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="631"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="653"/>
            <end position="704"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ34929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="757" mass="75245" checksum="48E9C71D9E08A5B7" modified="2011-01-11" version="1">MKFTHRGAAGALLGVVSLFATTSEAQFLNTTSSAPVTTPVSASTTVAGGSSSSVASATQSAVSPGATVDFATFRTLPAGVTVNVVVTDANGVQITLTLTSRGCRDVPNGQSPFTDLITRPVSTQQTCVAACSTGATVFKYNSFVNNACFCGNLERTDLTIVPCPANPSNRRRQNSPAPIIEVGNPGASSSLSSTVSLTSSVSGSSASSVSVSTTSSVSRSSSSTVTASTSGSTTSGSSTSGSSTSGSSTSGSSTSGSSTSRSSSSGTSSGTSSGTSSGTSSGTSTGTASSTATPSAGVLNPVNVGGFTYIGCYRSPSSFPTFSIVLSNSVMTNDRCITECSGRGKRYAATYANDCFCGDYIDDVNEPKVAEEQCNIPCGGAPSTQRCGGVFGTVTKRQLPGVIAANIRFTIYVRASTGTGVIPIVPSGTASVPSFITGVVLPTGLPTGIPGGDKCYGDDCYKVINCYGQYCTFNFGCYGPECDRRVVCTDGSCRPEACSGFDCGRKVVCNSGKCAFATKGMAEYEQKVTCYGNYCQVEKCSGDLCNQKCLCKDGSCTFTTCSASEALNKYEWNNGGYSIVKGCDGSCPTPAPPCSTCGYVVTPNPVTSVTCNGAACTTVVVTPPPVTKTPYLPAPPATLPPAVQPPVQTPGGQAPGGQAPGGQAPGGQAPGGQAPGGQAPGGQAPGGQAPGGQAPGGQAPGGQAPGVQPPAVQPPVTATGAPIAPKPTTVVTAGASNFVATLGAFVFSAVAAAALLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWD0</accession>
    <name>E3QWD0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10312</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697389">
        <property type="protein sequence ID" value="EFQ35168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099188.1">
        <property type="nucleotide sequence ID" value="XM_008100997.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWD0"/>
    <dbReference type="GeneID" id="24415677"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10312"/>
    <dbReference type="HOGENOM" id="CLU_1758665_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180920" evidence="1">
        <location>
            <begin position="24"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="148" mass="16542" checksum="4CFCEA9DBF3355CD" modified="2011-01-11" version="1">MKLSHLIALVMAVMGSLMRVAHCGGPKRGPFGRGRSSPDAIEYMSADPSPALSDTMGICHPEGYIEAGTAIQSIDDKLDKLDKLDKLDKLDKLDRLDRLDRLDRLDRLDMLDKLDKLDKLDKLDKLDKLSAMVESFQRDNSQTDNTDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWY2</accession>
    <name>E3QWY2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_10514</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697392">
        <property type="protein sequence ID" value="EFQ35370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099390.1">
        <property type="nucleotide sequence ID" value="XM_008101199.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWY2"/>
    <dbReference type="STRING" id="645133.E3QWY2"/>
    <dbReference type="GeneID" id="24415879"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10514"/>
    <dbReference type="eggNOG" id="ENOG502T4JX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1266807_0_0_1"/>
    <dbReference type="OrthoDB" id="10632107at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180898" evidence="2">
        <location>
            <begin position="24"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ35370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="225" mass="24627" checksum="4937542DCF096A28" modified="2011-01-11" version="1">MHIPSFCQAAAIGMAFYAMTAVAAPVNEPDATDIAKPNVDSMPDMSNAAPKGDDKDVLLTTSDENNGITEDRSRRCRRDIDGKRRDCDDYYYGDDDYGRRGRGRGRGRGDGGGDYNNRAVQNEPEEDGKDLAKRRDDGPDDGGRRGDRDRGRGRGRGRGGRGGDYGRAVQDEPNKDAKDLGKRGYGDDSYRHHGDDSYGYHGEEDEEARAATRGEDMEGGDGPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXI8</accession>
    <name>E3QXI8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10720</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697396">
        <property type="protein sequence ID" value="EFQ35576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099596.1">
        <property type="nucleotide sequence ID" value="XM_008101405.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXI8"/>
    <dbReference type="STRING" id="645133.E3QXI8"/>
    <dbReference type="GeneID" id="24416085"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10720"/>
    <dbReference type="eggNOG" id="KOG4178">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_7_0_1"/>
    <dbReference type="OrthoDB" id="284184at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047372">
        <property type="term" value="F:monoacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046464">
        <property type="term" value="P:acylglycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050266">
        <property type="entry name" value="AB_hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798:SF33">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G14860)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="31"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="332" mass="36948" checksum="7183F2A66A0BDB0C" modified="2011-01-11" version="1">MDLSKLTKKTINVSRGFTYTYYTSPAKGSRPTLILFHGWPDTARLWAGLINDHLLPHGYGVIAVDILGFGESSKPTDEEAYAFDGLTGDIVAILDAESINKVISLGHDWGSLTAQRLYNFYPARVCGVVMLNVTYLPPSGDFDFNKASESTKKMLGRSLFEYCYFFIAQDAVDIMNRNLESVYAVAFGEPETWIETFCTPDGMRRFITEGRTQPTLPFATPDHKADFMERFSRDGDGGFAAPCCMYKAMAAGIQNEADMKVAEEVKTVSVPVLYWGGTRDFVCIPEGLQQSIDDGLLPDVKSVLRDGGHWACLEKPDEFGRDVVGWLQERFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXW9</accession>
    <name>E3QXW9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">CwfJ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_10862</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CWF19 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697398">
        <property type="protein sequence ID" value="EFQ35707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099727.1">
        <property type="nucleotide sequence ID" value="XM_008101536.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXW9"/>
    <dbReference type="STRING" id="645133.E3QXW9"/>
    <dbReference type="GeneID" id="24416227"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10862"/>
    <dbReference type="eggNOG" id="KOG2477">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015540_2_1_1"/>
    <dbReference type="OrthoDB" id="2113965at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005684">
        <property type="term" value="C:U2-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040194">
        <property type="entry name" value="Cwf19-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006768">
        <property type="entry name" value="Cwf19-like_C_dom-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006767">
        <property type="entry name" value="Cwf19-like_C_dom-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12072">
        <property type="entry name" value="CWF19, CELL CYCLE CONTROL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12072:SF5">
        <property type="entry name" value="CWF19-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04677">
        <property type="entry name" value="CwfJ_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04676">
        <property type="entry name" value="CwfJ_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cwf19-like C-terminal" evidence="4">
        <location>
            <begin position="481"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="domain" description="Cwf19-like protein C-terminal" evidence="3">
        <location>
            <begin position="614"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="42"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="73"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="99"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ35707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="722" mass="83580" checksum="39C8AE7C87BE4267" modified="2011-01-11" version="1">MDGLDEFEKALAAEKGEKERIEREKEERRQRKKHRHHHHRDRSSDRRGERDSQRGSHRERDRDLERDRDRDHERHRHQRSRRHDGDEEDGHRHKRSRHSKDDEERRSRHRQKDRDDGNGGERHEKTSDPKEDLPIPDEEATPPEAKAADPPLVRDSWMTAPSALDIDYVQRKKEEAKPPPKEEPVRVIHDREINRDFGDLSNITTLDEKLPPTERTVSYKFGDNGSQWRMTKLKGVYSMAEQSGRSVEDVALERYGDLQEFDDAREEKIELERRKVYGEGYVSKEKPTGDLYRERLEKHRADRSAERDRAERERAEEFEQGTVIPDDAMQHTPMDQTALNRLRAQMMKAKLRKAPDAAKLEAEYNQAAASFATNGPQSVVLGVMDNRMLAGTRGEVTAIENKRGRERGNVEANEDMSIEDMVREERRTRGQAGGEGMRLAERIAKDSKFDNDLDYMDENADKLAKRVHKSEANLKNVAVNDYQKVSRILSNCPLCHHEDKGQPPLAPVISLGTRVFLTLPTDPEVSEGGAVIVPTAHHKNLLECDDDEWEEIRNFMKSLTRMYHEKGQEVIFYENAAAPQRHLHAAMMAVPIPYEEGATAPAYFKEAFLTTDDEWSQHQKIIDTAAKARDGMGRMAFRRSIAKEMPYFHVWFTLDGGLGHIVENSDRWPRGDLFAREIIGGILDVGPDVIKKQGRWNKGDRRVEGFNKKWRKFDWTRVLADG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZ73</accession>
    <name>E3QZ73_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_11305</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697411">
        <property type="protein sequence ID" value="EFQ36161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100181.1">
        <property type="nucleotide sequence ID" value="XM_008101990.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZ73"/>
    <dbReference type="STRING" id="645133.E3QZ73"/>
    <dbReference type="GeneID" id="24416670"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11305"/>
    <dbReference type="eggNOG" id="KOG0158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_2_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11062">
        <property type="entry name" value="CYP58-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF156">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="447"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ36161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="504" mass="55828" checksum="96B81D0361252115" modified="2011-01-11" version="1">MAIFADLWAITANKAVVLFGIAPLVFICFYLISNIFLHPLHKVPGPWIATISPLWLWYHSYIGDEATSIERLHSIYGPVVRIAPNDIDISDGAALAPIYSEKGGFLKAPYYANFDFDGHPTIFSALNPAHRSIRARAVVGMFSPASIRKEGDAILQSCAKRLAVHIKEQASNGGSVNMLTMGRCLALDAVTEYLLGKPYGAIAELESYKTSNSSTKLSASEFVDTFVAVGRFFLLPKWIFHGLEWILPKIFPDQEVDRSMDLVTHFCNQVVADANLERDQTYQARLLRAGISMEEAALQCMDLMFAGTDSTGMNFGTICWHLAQSPQAYQKLKDELASPAALQADPQTLPYLRSVVREGLRLSMANPTRLPRVVSPTGFSFSTKMPSGMTRTFEFPGGTCIGCASFSLHFNEDVFPDSRSFKPERWLDSTDKMLRDYIPFGLGPRQCIARNLASSELFWAVRELAVSGVLDGAQTTGRMKEGIIIDEWFNSKVPGHAIELTWGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZA1</accession>
    <name>E3QZA1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Multicopper oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_11334</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697414">
        <property type="protein sequence ID" value="EFQ36189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100209.1">
        <property type="nucleotide sequence ID" value="XM_008102018.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZA1"/>
    <dbReference type="STRING" id="645133.E3QZA1"/>
    <dbReference type="GeneID" id="24416698"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11334"/>
    <dbReference type="eggNOG" id="KOG1263">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006504_3_2_1"/>
    <dbReference type="OrthoDB" id="2121828at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF145">
        <property type="entry name" value="LCC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0186">Copper</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Plastocyanin-like" evidence="9">
        <location>
            <begin position="73"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="7">
        <location>
            <begin position="187"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="8">
        <location>
            <begin position="438"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ36189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="532" mass="59291" checksum="A5F20F0D6018C91F" modified="2011-01-11" version="1">MPPLEKQQLSQRRYQPNHVCLSILEPGRMAEKQIPRGAAGHARLTLKTCLPLVSHGDTNGRFKGQFWPQMDLSLVTVNGQFPGPLLEANWGDMVEITIHNNITDPEEGTAMHWHGIHQQGTGLMDGVSGITQCPIVPGGSFTYRWKASTYWSTWYHGHHGLQYGEGLWGPLIIYGPSHVKFDFDLGPVTLSDYYHYPVEKIALDAISTSNDPNVYAPKSNNHLINGKNSYNCSLAPANATCTNNAERASLRFKSGKVHKLRLINTSVEAMQIFSIDGHTLTVTTMDFVPVEPYQVEYIILGVGMRAEVLVNGTGNPKQSYYMRSRIQCAATNTTEALGTIYYDETPNTVVPTTTVVSALPNFSSTCGDPDLPKKKPIYKKSVPKPDLTLLYNITFGVNASGNHQWLMNNVTFKADWSRPLYIEAADGNANESDGFYNGTIDYPKNPARADTESLRRNGHLIVQFDAKNPGVWSFHCHTAWHASVGLYINFLVKPKTVRKSKIPDNTREVCRAWDNYRQLSGENSFPIDSGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZN6</accession>
    <name>E3QZN6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">lytic cellulose monooxygenase (C4-dehydrogenating)</fullName>
            <ecNumber evidence="15">1.14.99.56</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">GLRG_11469</name>
    </gene>
    <organism evidence="20">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="15"/>
    <dbReference type="EMBL" id="GG697419">
        <property type="protein sequence ID" value="EFQ36324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100344.1">
        <property type="nucleotide sequence ID" value="XM_008102153.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZN6"/>
    <dbReference type="STRING" id="645133.E3QZN6"/>
    <dbReference type="GeneID" id="24416833"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11469"/>
    <dbReference type="eggNOG" id="ENOG502RY3D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031730_1_0_1"/>
    <dbReference type="OrthoDB" id="4849160at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF36">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00562">
        <property type="entry name" value="CBM1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="19" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 17" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180977" description="lytic cellulose monooxygenase (C4-dehydrogenating)" evidence="17">
        <location>
            <begin position="22"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="18">
        <location>
            <begin position="315"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="262"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="16">
        <location>
            <begin position="272"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="282"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EFQ36324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="351" mass="35531" checksum="CB299C9FCA86D930" modified="2011-01-11" version="1">MGNLNLSSLLLALAAIVAAHGHVDWLVVDGAVAYRGWDSPAFTYSAPTYPVVGWKIDAPDNGFVEPANFGTGDIICHKNGSPAGGHATVPAGAKIQLIWNTWPDSHKGPVIDYLAKCNGDCETVDKTSLNFFKIGAGGVVDMSLANGKWADDVLIGNGFTWTVQIPTNLAPGNYVLRHEIIALHSGGNPNGAQAYPQCFNLQVTGGGSLAPAGVKGTSLYKANDPGVLFNIYTSPLVYPMPGPTLVAGLPSTVAQSTVRPIATSTATPPGGNPGNGGGGGATTTLRTTTGPAPVTTTRAATTTTSAPGGGGGGGATVPKYGQCGGQGWSGPTTCASGSTCQALNDFYSQCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>E3R043</accession>
    <name>E3R043_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Beta-ketoacyl synthase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_11626</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697427">
        <property type="protein sequence ID" value="EFQ36481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100501.1">
        <property type="nucleotide sequence ID" value="XM_008102310.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3R043"/>
    <dbReference type="GeneID" id="24416990"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11626"/>
    <dbReference type="eggNOG" id="KOG1202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_37_7_1"/>
    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009403">
        <property type="term" value="P:toxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19532">
        <property type="entry name" value="C_PKS-NRPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000019">
        <property type="entry name" value="Polyketide synthase type I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049552">
        <property type="entry name" value="PKS_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF20">
        <property type="entry name" value="HYBRID PKS-NRPS SYNTHETASE APDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21089">
        <property type="entry name" value="PKS_DH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="10">
        <location>
            <begin position="3"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="11">
        <location>
            <begin position="929"/>
            <end position="1229"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="9">
        <location>
            <begin position="2376"/>
            <end position="2451"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="8">
        <location>
            <begin position="929"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="8">
        <location>
            <begin position="1076"/>
            <end position="1229"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="8">
        <location>
            <position position="961"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="8">
        <location>
            <position position="1136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ36481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="2925" mass="316397" checksum="E536F639683D1F1B" modified="2011-01-11" version="1">MAPEPIAVIGSACRFPGDLNTPSKLWNFLSKPHDLQSQVPKDRFNVDAFHHPDGSHHGRTNARHGYFLSDIKTFDAHFFNVQAGEAESMDPQQRQLLEATYDALCSAGQTLAELKGSDTAVYVGIMTHDFELTKVGDLDAIPTYLATGAATSIASNRLSYFFDWHGPSMTIDTACSSSLVAVHHAVQQLRSGTSKIAIAAGANLMLSPLNFITESKLSMLSPTGRSRMWDAAADGYARGEGIACVVLKTLSQALADGDTIDCLIRETGVGQDGRTTGITMPSNVAQAALIRATYARAGLDLSRHEGRPQFFEAHGTGTPAGDPQEAEAISTAFFSDGTEDMQDLYVGSIKTVVGHTEGTAGIAGLLKCSLAVQNGIVPPNMLLEKLNPRVEPFCEHLRVPKEATPWPAVAEGQPRRASVNSFGFGGTNAHAIIEEYVPAASSTSACPSSTNVLPLVFSARTKRSIKANMESILSLIKTTPDINMTDLAWTLLQKRSVLPVRHAMAASSVESLCKALEAAVKDDVGLEYTPKTTEAGRILGIFTGQGAQWPAMMKQLVLHLPFVAAVIDELDAALQTLPEQYRPSWTLKEQLLLEGDASNVRLAAYSQPLCAAVQIVLVRLLSAAGVVFEVIVGHSSGEIGCAYAAGFISAGQAIRIAYLRGFTSHHASSPTGQVGGMLAVGASLEDARELVELEAFAGRVCIAACNSPDSVTLSGDMDALEEIAEILQDESKFARLLRVDKAYHSNHMLPCSEPYMTALADCGCAVADGTGTGAKWYSSVREGNIMTRADVTPQYWRDNLVSPVLFRHALEQAGLENTLDAAVEVGPHPTLQGPATNTLATVMTDPIPYTGCLQRGGDDVAAFATGLGYIWERLGALNAVNGTTLVAAMQPTPPVDISKRLPPYAWDHSRVYWSESRATKAALHGPRPHLMLGTALPSSTATTLQWRNFIRPRDHEWMQGHELQGQAVLPAAGYVVMAMEAALYIAAGKGVRVGLLEMLDLSIDKAVTFDDADSMAELTLTASVTYSDDAQIDLEFGIASCLSRESTLSLSAHGRIVVTLGEPVSLPSPGPAPPHANPVDIRLFYRELDNIGYDYSNNYRCVYSMLRSTSRASGHMAHPRLVDGANPIVLHPANLDLAFQTVMGAYSSPGDKRLRSLYVPTRVGRIALVPAVCASTLDSLEGVRYNSVNTHDGGDYLSGDMEVFDKETNAVLYSVENMHLVPLTPPSAIEDHRPFTKTVWGPLNPDKVLDIERLWATEQDKEVIPIIERAVYYFVRKFLAELTEEDRKKASVGNQRYIYWHEHVLKLARDGKHLFYKPEWEEDTEQSIDKLLQENWYHPHLRLAKLVSDNSLSTIRENKNPFIWMNENGLLTEFYTSYLTSGPTWEYGQHLVGQIAHRFQNMDILEIGISPRLTGASILAIPELGFNSYTFTDISAAFFEKAKEKFSPFLERMDFRKLDITKSPAEQGFKTHAYDMIIASSVLHATPNLTETMANARTLLKPGGHVVICEATNKHHMRVGYLFGLFADWWAGVDEGRTLDPFATREEWDAIFKKTGFSGIDSVTTDRESHLFPNTLLSTHAITPEQLRLDEPLSAPPKPQHPQLVIVGSGAALAPIMRTIRELLPSRDPLVVPSLVELAAADLQPKATYVVLSEVDSPIFDEFTEEKLAAVKRLFFGSNAGGVLWLTEDAWVSNPRQAMGIGMLRSVRLENPDVAFQCLDVDRLEDLNARFLVEQILRLEEGIPENTVWTLEPEICVVDGRPHVPRIKQDTARNHRLNSVRRPILEEVDIGTVPVVLQNTPPPVLVTGRISRPLGSPPDAASQTVHVHHATVKAIRVHGLGYFHIVTGTTVDGAVLALAKVNASIVTVPVKHTFPVENTSANTLLSSVANLVAQGVVDTPPGSSALVYSPPRFCVDAIKQVAVARSVSVHIASVDESVSQGIVLHPRDTDRAIKQKIPSGIAVLYDLSSDKHATSLGPRLACVTGCAARNSSYIFRSKAAAFAYSDALEASQLQLVAESISTPTLNIDIIASCPITKPADAQDALDAIVDWKAETKVPARVSPVDAGTLFVNNKTYLLVGLSQSMGRSIAAWIIKHGGRHVVLSSRNPETPETKWLEDMERLGGKITVLAMDASSAQSVDAGLSTLCDVHNLPPVGGLAYGPLVLKDALLNNMDLATMDMVLNSKVPGAKIFHDRFCDPEKDPLDFFVMFSSAALFGGNPGQTNYTAANAYLQALGQYRRSKGLAASTIHIGAVMGIGYLTRNSREAEFQEKSDVDTLGEAEFLTLFAEAVVSGRRVNGVDSVYAKRVIDMSETEIGSGIPALESRHKETIKFYHDPRFGNLKTPENRSDAAAAGDGKMSVKEMLAMATTMEQVRAAIIEGLSDKMRGVLHIPPEESVNAAAPLLDQGIDSLGAITVASWFSKQLLVDIPILRVLSGASIDDLAAEGASRLPPAAIPLVADAQVAAAGSHDSSTVSSFDDGASTLLSTPDEAGVPFEGVVRKAPMSLTQEYSFTRQASLPDVTISHNTIGVIMEGSLSTEKLAQAVTAAATRHDTFRTAFRPSESSPTPLLHVLSAPTWGLHAVSVASRDEAEAELAKLQKEPYDLESGETFKTALFTWSPTSHLLVLAYHRLAGDGSTTENLVAELSQLYTDAVLPPAPQYTDFAVKQRNLLSSGGMDASIAYWTGLYTPVPAPLPLLPLPGAKSARGPVSWDQHTAMSRLSAVLAFRLKERTKKLRTTPMTFYLAAYAALLSDLSKQEQVSIGLADTNRSSVADLSTMGYFANLLPLRLTSSGTFTATIESAKEAVRQALSHSVVPHDLISSRLGLDNVSPQEMTHAPLFQAVFDYRQGATESGTIGGASIVEVLASRECTPYDVVLEMSDDPTKDPLVTVKLQSSVYGEGDANVFLGRYIELLTALCKGEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0H8</accession>
    <name>E3R0H8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_11761</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697446">
        <property type="protein sequence ID" value="EFQ36616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100636.1">
        <property type="nucleotide sequence ID" value="XM_008102445.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0H8"/>
    <dbReference type="GeneID" id="24417125"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11761"/>
    <dbReference type="HOGENOM" id="CLU_2015092_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="55"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="111"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ36616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="123" mass="13964" checksum="D81F24B31F6A2C01" modified="2011-01-11" version="1">MVAVWNSAVRNIKEAQKAFAMLHRGCKANVDSAASERDGLELCVQRYQSSVHWGNEKIMQHIEEAQRQLGLAQERLRKRQEGFSLWGELVGLLEGAELTLKSRIQSLGPNDNDDDEDDREDVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0T2</accession>
    <name>E3R0T2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NTF2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_11868</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697484">
        <property type="protein sequence ID" value="EFQ36720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100740.1">
        <property type="nucleotide sequence ID" value="XM_008102549.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0T2"/>
    <dbReference type="GeneID" id="24417231"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11868"/>
    <dbReference type="eggNOG" id="ENOG502SB73">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096573_1_0_1"/>
    <dbReference type="OrthoDB" id="5596743at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058645">
        <property type="entry name" value="NTF2-like_dom_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26534">
        <property type="entry name" value="NTF2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="domain" description="NTF2-like" evidence="2">
        <location>
            <begin position="46"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ36720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="190" mass="21029" checksum="17D8F4FCC65E86D9" modified="2011-01-11" version="1">MAPPLVFVLLLSGAVGQMMLMWLFESFSLLPSKWDAEQRPTPPPACLRTEDGRDLAAEFQRLIRNYSAKAADRLLAPDVVAHCDGMNEMAGKPLGAPTYHDREELKTALERQSGRPTPVTLRTVDVVTCNTVVLKWTAVFGQEKLPVRGIQILTVQKSAPHYGWAIKTIDTEFNSLAYLVDLGGTYSMPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>E3R122</accession>
    <name>E3R122_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Beta-ketoacyl synthase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_11956</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697561">
        <property type="protein sequence ID" value="EFQ36810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100830.1">
        <property type="nucleotide sequence ID" value="XM_008102639.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3R122"/>
    <dbReference type="GeneID" id="24417319"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11956"/>
    <dbReference type="eggNOG" id="KOG1178">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_6_2_1"/>
    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.10:FF:000011">
        <property type="entry name" value="Sterigmatocystin biosynthesis polyketide synthase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.129.110:FF:000001">
        <property type="entry name" value="Sterigmatocystin biosynthesis polyketide synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000031">
        <property type="entry name" value="Sterigmatocystin biosynthesis polyketide synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="FAR_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030918">
        <property type="entry name" value="PT_fungal_PKS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032088">
        <property type="entry name" value="SAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04532">
        <property type="entry name" value="PT_fungal_PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF40">
        <property type="entry name" value="NORSOLORINIC ACID SYNTHASE STCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22621">
        <property type="entry name" value="CurL-like_PKS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16073">
        <property type="entry name" value="SAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="8">
        <location>
            <begin position="373"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="9">
        <location>
            <begin position="1298"/>
            <end position="1604"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="1652"/>
            <end position="1730"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="1771"/>
            <end position="1846"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="5">
        <location>
            <begin position="1298"/>
            <end position="1430"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="5">
        <location>
            <begin position="1457"/>
            <end position="1604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1728"/>
            <end position="1747"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1852"/>
            <end position="1872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1738"/>
            <end position="1747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1852"/>
            <end position="1863"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="5">
        <location>
            <position position="1330"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="5">
        <location>
            <position position="1517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ36810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="2295" mass="251672" checksum="3E20E5692C8CCF17" modified="2011-01-11" version="1">MYKNQGPDISLYLFGDQTFDIAEQFKDLLRYRNNPLVENFLEKSYQLMRKELYLLPSAVREGLPRFTCIEDFVLLGPQNIGKCNALELALTCIYQIGTFIRRNDLGSYNDGECRVIGLCTGALSAAAVSCSTSPLDLICTGIIAVKTAFRIGLKVTEVAGRLAASDHQHQNWSLIVSGIGISEIINEFCHETSLSAASRPYISAYMEKSMTLSGPPPVLKQFIKYASSSGLRFAPISVYAPYHAPHLYSSTNVAEIVNSLMPDELALRREIVPVLSSTGSQVHGGTFRSILEAATAQILLEPISWSHMLNQLQTCLAEVRPKSFTVFSTGSHMDETIYAALNKTEWRYLTPVNVAQTESARAQSFEPQNGTNKAKLAIIGMSGRFPGAKHNEAFWDVLRQGLDLHKPAPALHWDVKTHVDPTGKIKNTSATPFGCWLDDPGAFDAKFFNISPREAAQIDPAQRLALMTAYEAIEQAGIIPDATPSTRRDRVGVFYGVTSNDWMETNSAQNIDTYFIPGGNRAFIPGRINYCFKFSGPSYAVDTACSSSLAGIHLACNALWRGEIDTAIAGGTNVLTNPDFTAGLDRGHFLSRTGNCKTFDDGADGYCRGEGIGTIILKRLDDAIADHDPILGVVLGAYTNHSAESESITRPHVGAQRAIFSKILNEASVDPFSISYVEMHGTGTQAGDAGEMSSVLEVFAPPPSQVVKVRKSDEPVYIGSVKPNVGHGEAASGVTALIKVLLMMQKNEIPPHCGIKTIINRKFPTDLKERNVHIALEPTTWPKSSDPSRPRRAFVNNFSAAGGNTALLIEDAPILPALPTATTSTRPHLIAVSAKNGASLQGNLKSLLRFLQENEDIPLGQISYTTTARRLHHQHRVMLHSSTVGEACSQIEAALRDGTGMKRPKSAPKPIFCFTGQGAQYPGMGKELWDNFSLFRSEMSQLDKMGQTLGFPSVMSVVQSDEKDISGFPPTVVQLANVCMQIALARLWASWNITPAAVLGHSLGEYAALNIAGVLSDVDTLYLTGRRAEILERKCARGTHAMLVVMASVEKIAALLKGEAYEIACINSPVETVLAGTVQRVAALKEMLTASGLKSTVLKVPYAFHSSQITPISDEYESAASSVTFSKTKIPVLCPLDGTIADGENHPFNARYLVRHALEPVRMMQTLLNAKNEGIINDRTVFIEVGPHPAIAGMINPVLGKQTACVASQSRGRSLWKTLEPALSTVYMLGANVSWGEYQRDFESTHKVIKLPAYSWDIKDYWMQYVNDWSLRKGDPAVVVSKEPMMSETNKLDSTTIHRVVEETGDAAQVRLIVEADIQRDDLSPLVQGHEVNNIPLCTPSVYADMALTLGKYLLDKYQPQTRHRLVDVSDMTISKALILRAGAAEQLLQAHADVDWKTMSAQVKFMSFNNKGKLQEHSRCTLVFKDGNLQEKLQKDLDKVQQKLKALRDGIAQGTTARFNTAMVYRAIRPLARFHNDYRAIDEIVLNSNTLEASSVLSYGAVKRGGHFHTHPAIIDSLTQSCGFTMNCNDSSDLDVDVFMNHGWGSFQIFEPIDFEKSYTTYTHMQAGQNNLWYGDVVVLDGHKVVAFFGKIAIQCVSRRVLKVILSMESGQKSNAQQASAVKAPQKVAPTRPVVTIPSSSQPSTKTSAPSALSNKFSTALNIIAEESGLSVDDLSDNTVFSDVGIDSLLGLTIAARLKEELDVDLEFNSFFYEFPTVKDLKHHFGNGPESADEMSSPDTPMSQSGWDDLSTPITVPSTPTGCADQPSQKVDFNKVLDIISEESGVAVEELTPDTNLGDSGVDSLLSLVIVSRLRDELDLDIQQESLFLDCPTVADLREVLTGRGSRVAAPKSISPASSASSNWTPAQPVVTMESKASPLTATDKDALEERERAVDACVKKYTAGWTPPTSAPYGAMPIKEEKVVLVTGASGSLGGHLVYHLAQLPDVKTVICLNRENKAEPFTRQLKAMRDKGIRYPENLKHKLKVYQTDYSRPNFGLDEKTYVSLWKTTTHLIHQAWPMSAKRAFSGFETQFQVLRNLADFATLAASQYPAGFKFSFQFVSSVGVVGHHRLGNEPTIVPEELVGIESVLPNGYSDAKWGCERMLAATMGKHRGFFRPMVVRLGQIAGSKTSGYWNPMEHFGFMMKSSQTLNAIPDVPGTVYWAPVNDIAATCSDLILSDREPFPVYHIENPHGIPWHHMTRVLAKAIGITDLIPFKEWVRRVAEAPQRNNPASTLLEFLDETYLRMACGGLVLGVDHTLEHSKTLRDLAPVNDEIVNKYVHIWKEIGFLANN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3R152</accession>
    <name>E3R152_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11987</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697618">
        <property type="protein sequence ID" value="EFQ36840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100860.1">
        <property type="nucleotide sequence ID" value="XM_008102669.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R152"/>
    <dbReference type="STRING" id="645133.E3R152"/>
    <dbReference type="GeneID" id="24417350"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11987"/>
    <dbReference type="eggNOG" id="ENOG502S791">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106738_1_0_1"/>
    <dbReference type="OrthoDB" id="2148716at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13577">
        <property type="entry name" value="SnoaL_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="15"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="166" mass="18226" checksum="98C49AAAB7843873" modified="2011-01-11" version="1">MAAPYDGLEMPVALQALTEREAIEDALNRFLFGMDSNNTELFDSAHTEDARWELSGSSGGRVLSGLKAIHEECFDPTISKLDTTHMVTGTRINITKSGSEAVMTAIFNAQHYAAGQGKVKGSMFFYTGGLYKIDFIKDATAGLWKIKCFAMKCLWSEGDVRVMGHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3R154</accession>
    <name>E3R154_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HypA protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_11989</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697619">
        <property type="protein sequence ID" value="EFQ36842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100862.1">
        <property type="nucleotide sequence ID" value="XM_008102671.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R154"/>
    <dbReference type="STRING" id="645133.E3R154"/>
    <dbReference type="GeneID" id="24417352"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11989"/>
    <dbReference type="eggNOG" id="ENOG502S69W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019145_2_1_1"/>
    <dbReference type="OrthoDB" id="10004862at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025337">
        <property type="entry name" value="Questin_oxidase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35870">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G03330)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35870:SF1">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G03330)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14027">
        <property type="entry name" value="Questin_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ36842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="486" mass="54278" checksum="1ACAB915B4DE3481" modified="2011-01-11" version="1">MMEQSSLSAVTSVQLSPETTPGFTHVDELTTESAEVTSRLLTENHTQFHTRWKLTFHNHLAHHLLTLWALGASPSEIQAMWNYNAAYQTGLHDPDVESKHLDLQNPQAFKQALGKDENYAVFLKFFENEIHDKGLPEVLQIYLLDGSELANDIFYRLWTDLMHPAIHLGCGLEFNQPSIIAEALAGACVHQDWARVFLEPTEKSTAPHSDVSSSLFIQMLESLHNDPLISSGVKHDDPFNKIPDGLLKRVSGEAFAPHLSIFQCSEQNGDLRDKMTDMFYGCVYMVSAAQSPGKHEALDFVTLHSVTMAGFFPAILALDWMSDHDKARLLVAKARVDGVMYAGCGVPFLYPGRVTHYIPKHPDQDWSQLLKRAIGYYDEGHAAKFVRAMLSLQVLDGPPAGFPIAKPDLIKVVHMALDSIERAMEPGGSEMPESAAQAVINRIGLGGEMVKNNMVRWVFYNGLEKAWDFVPIKKKKSCNNLLKELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2D6</accession>
    <name>E3Q2D6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Thioesterase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_00381</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioesterase PaaI family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089257.1">
        <property type="nucleotide sequence ID" value="XM_008091066.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2D6"/>
    <dbReference type="STRING" id="645133.E3Q2D6"/>
    <dbReference type="GeneID" id="24405746"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00381"/>
    <dbReference type="eggNOG" id="KOG3328">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089876_12_0_1"/>
    <dbReference type="OrthoDB" id="46529at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047617">
        <property type="term" value="F:fatty acyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03443">
        <property type="entry name" value="PaaI_thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.129.10:FF:000033">
        <property type="entry name" value="acyl-coenzyme A thioesterase 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039298">
        <property type="entry name" value="ACOT13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003736">
        <property type="entry name" value="PAAI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00369">
        <property type="entry name" value="unchar_dom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21660:SF11">
        <property type="entry name" value="FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G04355)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21660">
        <property type="entry name" value="THIOESTERASE SUPERFAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="3">
        <location>
            <begin position="74"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ25237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="167" mass="17271" checksum="98FCA6DC2175D9F7" modified="2011-01-11" version="1">MSSTPSQPPPPAAASAAASDPATFAHIEKYIATRCNASPIYAFLFGPGLRLTHASKGLVIARLPVAAEHLNTAGSIHGSVSATVVDWAGGLAIASWDMREATGVSVDINVSYLSGAKLGDEVEIEGRVEKLGGSLAFTHVNIYKVAADGTRGATVASGRHTKFVRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2Y8</accession>
    <name>E3Q2Y8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_00111</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ24967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008088987.1">
        <property type="nucleotide sequence ID" value="XM_008090796.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2Y8"/>
    <dbReference type="GeneID" id="24405476"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00111"/>
    <dbReference type="HOGENOM" id="CLU_1885604_0_0_1"/>
    <dbReference type="OrthoDB" id="10400411at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ24967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="135" mass="15229" checksum="CD943D32670BE84C" modified="2011-01-11" version="1">MGNLFLVCGEHPVFFCGHHFSTAEIVSGRHFTRYIDRSIRLHRQRASTGGPLTSFSLLRFTLYTCFPDDFTTPPLCDLDIASIGVWRLPPHPAYDTLPSVQRTYDTPVRGTGIAKQRHRDGIHIFISWVDSVGSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q311</accession>
    <name>E3Q311_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome b561 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_00134</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ24990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="RefSeq" id="XP_008089010.1">
        <property type="nucleotide sequence ID" value="XM_008090819.1"/>
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    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00134"/>
    <dbReference type="eggNOG" id="ENOG502SCDZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007077_0_0_1"/>
    <dbReference type="OrthoDB" id="19261at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd08760">
        <property type="entry name" value="Cyt_b561_FRRS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1770">
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    </dbReference>
    <dbReference type="InterPro" id="IPR006593">
        <property type="entry name" value="Cyt_b561/ferric_Rdtase_TM"/>
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    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47797:SF3">
        <property type="entry name" value="CYTOCHROME B561 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47797">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05805)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="66"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
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            <begin position="136"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
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            <begin position="174"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
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            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
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            <begin position="341"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b561" evidence="9">
        <location>
            <begin position="68"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
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            <begin position="278"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="363"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="497"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="278"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="425"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="448"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="475"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="497"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="519"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="539"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="553"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="579"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="642"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="657"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="672"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="691"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="741"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="796"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="832"/>
            <end position="843"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ24990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="854" mass="92574" checksum="6D9258EB4E7194E9" modified="2011-01-11" version="1">MAPANGYSAPGVASYDSNTMSVGDGTWDFEKNTFLLPNLVGLNFETMQYNGMGNRFSTVAQYHTLVLAHGVMAAIIFLLIVPVSVFIARFYTAKPGYAIPYHAQLNILAALMLVAVFVLGWFAVGPERSWTNPHHAIGLAIFILFLLQIIGGRLVRNIRGRSIRKMFHRWSGRLIALLGIIQVALGLTLYGSPKWTFIIYSLWLAFLLLIYFVLSYRAEGTGRGRETYISGGRSEGPSGESEYYSDVYTEKSKGNKWLAPLAAGATLAALLGRKKFKEKEKEASPERSKSRSRSRGPEVVGSRRGSASYLTSRRGSDTYLEDEKYTEVDSRRDGKKSGGGFLSKLLGVGAAIGAGKLVSNLFKRKEKQPHDEEYSAVSAETPGRRPSRSYPATSEYTDYTDWTEDTPPPRRGPREGSILPPPGGPTAAAAALSAAEPRTNRPPHARTRSQYSFEDSEYSSYVSPSRRKDDPSAGPAGGAGKGVMAGLGLGWLAKKLADRKSKRAEEQRLRDEEDMRSGITGSRYTGDGFSSPSHDQRGSHRASGRRPRPPMSAISTEITEMTGSSELEPRPPGTGYGGPPMPPLSAGPPPRPRTPAGSGGYSQATSRHDVIDPVSMPPMPPDPAGVLHRESESEGYMSPGGRPRRRDSSKRRRAGEEAAAAAVASASALAAAEDRRRAHSERSQPVSVKVRVHDDKDRNITLRRLTEEEAAASRRSESKRRRGSLSSLSGIEVGSGRRYRRDSSQRRAESAAEYAAEAGDNLPPPNPAFAAGRKPKDSAYYSGGPPVQPAPMAGATVSSIGSENTHGTWSQMSPSPSAPQTNPVGSAAADNRRRRRQERRRSSASRPTGVDMFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q397</accession>
    <name>E3Q397_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00643</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089519.1">
        <property type="nucleotide sequence ID" value="XM_008091328.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q397"/>
    <dbReference type="STRING" id="645133.E3Q397"/>
    <dbReference type="GeneID" id="24406008"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00643"/>
    <dbReference type="eggNOG" id="ENOG502SANZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059580_3_0_1"/>
    <dbReference type="OrthoDB" id="5345504at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046591">
        <property type="entry name" value="DUF6649"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20354">
        <property type="entry name" value="DUF6649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="191" mass="21129" checksum="BE036C490A3CBCDD" modified="2011-01-11" version="1">MAPNAVSTTSPPSTSPTSRRRRRDRKPPPSDEEVMQLDDTKHKVYIFNMDDELSSSESEPDDGKLVFLPDIEKHLRATRIPPSLLANHEGQLAGMQVVLYNEPASLTVPPEQDSVRKAIVESRTRMRERQRLEREGKGSPVQMPPPFVSQQPVSTFISGSQQPVSAVAPNPPTPSETSASVDYNPDAMDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3H3</accession>
    <name>E3Q3H3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA-dihydrouridine(47) synthase [NAD(P)(+)]</fullName>
            <ecNumber evidence="5">1.3.1.89</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="20">tRNA-dihydrouridine synthase 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="28" type="ORF">GLRG_00719</name>
    </gene>
    <organism evidence="29">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="29" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="29">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="21">Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs. Catalyzes the synthesis of dihydrouridine in some mRNAs, thereby affecting their translation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="22">
            <text>5,6-dihydrouridine(47) in tRNA + NAD(+) = uridine(47) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53364"/>
            <dbReference type="Rhea" id="RHEA-COMP:13539"/>
            <dbReference type="Rhea" id="RHEA-COMP:13540"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.89"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="22">
            <dbReference type="Rhea" id="RHEA:53366"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="25">
            <text>5,6-dihydrouridine(47) in tRNA + NADP(+) = uridine(47) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53360"/>
            <dbReference type="Rhea" id="RHEA-COMP:13539"/>
            <dbReference type="Rhea" id="RHEA-COMP:13540"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.89"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="25">
            <dbReference type="Rhea" id="RHEA:53362"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="23">
            <text>a 5,6-dihydrouridine in mRNA + NAD(+) = a uridine in mRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69851"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="23">
            <dbReference type="Rhea" id="RHEA:69853"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="24">
            <text>a 5,6-dihydrouridine in mRNA + NADP(+) = a uridine in mRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69855"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="24">
            <dbReference type="Rhea" id="RHEA:69857"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the Dus family. Dus3 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.89" evidence="5"/>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089595.1">
        <property type="nucleotide sequence ID" value="XM_008091404.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3H3"/>
    <dbReference type="STRING" id="645133.E3Q3H3"/>
    <dbReference type="GeneID" id="24406084"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00719"/>
    <dbReference type="eggNOG" id="KOG2333">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013299_7_0_1"/>
    <dbReference type="OrthoDB" id="259935at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
        <property type="term" value="C:nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102265">
        <property type="term" value="F:tRNA-dihydrouridine47 synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000145">
        <property type="entry name" value="tRNA-dihydrouridine(47) synthase [NAD(P)(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45846">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45846:SF1">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25585">
        <property type="entry name" value="zf-CCCH_DUS3L"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0288">FMN</keyword>
    <keyword evidence="12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="18" id="KW-0520">NAD</keyword>
    <keyword evidence="16" id="KW-0521">NADP</keyword>
    <keyword evidence="19" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="29" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0677">Repeat</keyword>
    <keyword evidence="11" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="15" id="KW-0862">Zinc</keyword>
    <keyword evidence="14" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DUS-like FMN-binding" evidence="27">
        <location>
            <begin position="360"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="domain" description="DUS-like FMN-binding" evidence="27">
        <location>
            <begin position="607"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="26">
        <location>
            <begin position="1"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="26">
        <location>
            <begin position="258"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="26">
        <location>
            <begin position="7"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="26">
        <location>
            <begin position="29"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="26">
        <location>
            <begin position="90"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="26">
        <location>
            <begin position="130"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00031322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00045934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00048266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00048342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00049447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="ARBA" id="ARBA00049513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="27">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="EMBL" id="EFQ25575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="29">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="767" mass="86841" checksum="6E21706D5879302D" modified="2011-01-11" version="1">MENQAPHIDESEQRAAKRLKVDDSTQPSEVAAAEEQRAAVNEAYEHVEPVPANGNAGEKVDVQMSEAPAADEKRPANGGSAAVQTSDATAEPKKDDRDVRRGQAPIKAEFLVYREGQAKEQEEVIDDDAAEGRDQGDGRDARDSRDKRDKKKREKGQNKERSFGHFDDALRLCNSRAYTPEFSPRDCKFGDRCNMLHDLRKYLKEGRREDLETFDGKCPVFEQLGVCPSGWKCRFVKSHMKEIDHEDGRKELVLVEEPKEAKMSGEAPTDAGREDLRPGVYNNTENQLKIDLSRKRVDFTETDKYITWMNKEARLGDEFHQRRKDQIISNQEDLRAQFVDPPLKPSEKRKLYFGKETPALAPLTTQGNLPFRRLCVDLGAQLTYSEMALGMPLVQGVKNDWALMKAHESEISPPKVNQVSSNIVQGYDNSRDLKFGAQISGSQAWHCVKAVDLLNRYVPHLRLIDLNCGCPIDMVFKAGGGSALLEAHGKLERMVRGMNTVSGEIPITVKLRTGVRQNRPTATTILGKLAFGSRENRDRLGAPGCAAITLHGRSREQRYTKKADWGYIAECAAMIKSYNEEKDKITDTAREPDESTLPNAKDGRMFFLGNGDCYSHVEYYEHIEKAKVDTVMIGRGALVKPWLFEEIEKGQYLDKSATERLAYVEKFCRFGMEAWGTDELGLGFTRRFLLEWLSFAHRYVPIGLLEYLPPNLNDRPPAYHGRNDLETLLASKNYRDWIKISEMYLGPAHPNFTFQPKHKSHSYEAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3H7</accession>
    <name>E3Q3H7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">STB6-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_00723</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089599.1">
        <property type="nucleotide sequence ID" value="XM_008091408.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3H7"/>
    <dbReference type="STRING" id="645133.E3Q3H7"/>
    <dbReference type="GeneID" id="24406088"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00723"/>
    <dbReference type="eggNOG" id="ENOG502QT8Q">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010065_0_0_1"/>
    <dbReference type="OrthoDB" id="19806at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070822">
        <property type="term" value="C:Sin3-type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038919">
        <property type="entry name" value="STB2/STB2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059025">
        <property type="entry name" value="STB6_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31011">
        <property type="entry name" value="PROTEIN STB2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31011:SF2">
        <property type="entry name" value="PROTEIN STB2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25995">
        <property type="entry name" value="STB6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STB6-like N-terminal" evidence="3">
        <location>
            <begin position="65"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="23"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="439"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="598"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="838"/>
            <end position="872"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ25579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="892" mass="99231" checksum="74B31CD11905C8A3" modified="2011-01-11" version="1">MAFRFPFPTNDPRMHREEELTLARVASQRGGNRPSPLDTPLPPEPQKEASTEPAVPSPLSAMKRKWVFADPVAFRYLESDPSVTVLERRGVLQGYELYLVEQWACSRKSPTLVIVTYTGDPKHSVVVGVLAVPADESIWSDRLRFYFKAIHQYHARPKETPLGDVMVTNLSSFPSALTVIPVPEGDIRTHRQAFIVNENLKRLGCSGRSGMNLSDPTPATQAKFYQLFKTSEKVPFSQSAVELVKLCQVSLFMFGKLDMEYIDGLLCDKTEESIGNWWTEIGAECYNVEPTDGILGPTTVAALLGLLMGARNRLHYYGAPVSKDVFDIESTKRGVGYFQKAYKLERTRRLDRQTILKLHAVTAKAAAGEGWGVQKAVKSTVAEIGGKRGELVIGMVAGKDKAGIADIETIDIDRFIALAYGERAKWLWYGKPRRTAPELHEKPKDVAQPLFGKDEVPPPSGKRTQSLPLEEELQRQKEESPGVYSTPAPASAVSVVDNPAEKDALRKTVFKSVAGRVSDAKSGLGRIKDVVGTGLRGHASRPSRDDFGENGYSNSAPGISNLVQSSATLSPVMVGRAFTWKNKPEEYLTAFKKEAEAAQELRESSQELENTPVVSKPTREALDPSSAHLEGGFSTPPNESVKEGLDRVQTSVAGSVVDEADLHGPFEAERTGNTALSFLQRRHSIAVSRLSYKHPMNEARWPRRLSFGDAEEAVLRWEEITELYDDKHFSTADALQQQASLAEFARSLYDSIATITREVNPWVESKIKAVDSLDEHYSREQEGLQTLYYQLSEAYHRVKQSSTELIAEERAHITEAIKEVEVLVARLEYEINGLVSKVDDVEDGVRLFERQVEDVEKRAEELKRTLETESWAHWFVRTLTGIGTGPNITRGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3Z2</accession>
    <name>E3Q3Z2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00888</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089764.1">
        <property type="nucleotide sequence ID" value="XM_008091573.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3Z2"/>
    <dbReference type="STRING" id="645133.E3Q3Z2"/>
    <dbReference type="GeneID" id="24406253"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00888"/>
    <dbReference type="eggNOG" id="ENOG502S9SQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093552_1_1_1"/>
    <dbReference type="OrthoDB" id="5422613at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38167">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38167:SF1">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="215" mass="23576" checksum="C33EFCB3491773D0" modified="2011-01-11" version="1">MAEHAVQRDAVQAARAKEELDAVGSIPEADARKVLYYLCSEDEGVRRKALDFYQGAPKRDVCTHCEKEFDPDNNASDACCYHPGDFELDEELEVWDGMDDYDWPPEHYQRDSESNREDIPEGFRWSCCNRVGDVKGCQTGRHEGNGANTAAATTYGLALEVNRMKAKRLGELAGRAGKESGIHGPGEQQASNKRKADGEPGDGDASKVKKGAGAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4B9</accession>
    <name>E3Q4B9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_00575</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089451.1">
        <property type="nucleotide sequence ID" value="XM_008091260.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4B9"/>
    <dbReference type="STRING" id="645133.E3Q4B9"/>
    <dbReference type="GeneID" id="24405940"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00575"/>
    <dbReference type="eggNOG" id="ENOG502STJP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_296817_0_0_1"/>
    <dbReference type="OrthoDB" id="3538943at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="336"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="510"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="694"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="809"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="930"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="340"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="562"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="731"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="836"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="863"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="942"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="979"/>
            <end position="989"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1001" mass="108584" checksum="AF86C03135D61EDA" modified="2011-01-11" version="1">MAVIASPTSRSDASDSSTPFGILKDAPIPQKFTVIPKNQNALLERKDSWISALNNDSQKGAVNVPPNVLETVKYFHTSRTLPPAAQKPNVEGSSGPLQMEAELAVPSAPSQEQEDGVSLNSSPGIPVSSWPESLPPSPHTSRQHLTPSPAPSIKSQIVTERQSGPLSVAPESPPPDRPSSPQIASSPPMQPAPKRHIAPLAGSKRRPLEAFPSSSAGLEDELETAIPDALVEATPPINRMAARVATASQAVTSPPCGQGSMVPSTYRDVKSPEEKAQAPNKRRCQGMKVIVFSSTPEDQPKGSSNCGKTPARPAIPLAAPLQEPSSLSSAFPIASALPKTDTQSSLRTSRNVEATNGQQAGATPRPVPPAPGPAHDSEDHVMTGTNTVPEARRAMPNDGSFDQPAQSSRCQDIISYLDHEWNAENLDWLPPKLKHFRSALTARSLENLQKITSLAIKNGTRLSRLWSEPDGLLYRSAQQQTNGKLNFPEELVHMTLDLYGTEMAGIEGHPARAPEEVLKGPSRQTSRHEVATQTRTTNPSPPTSPTVVQAPRDAPSSPQVTNKHERPIETPPRPPREVVAKTFARDPLEAFRNAYPSYSGSTGDFVKACLTIKDLRRKLLLPKWLYDDFIRAFVDGFIPYIETLDDDEAPLSAYQWYVEYVDSPAFQGGVVTRENLHQVFRVYHSAYMSARGSLSGKTSTHPGVGLEPSTETTGVDIERGPQTRIPQVVEPRPRVRPKEPHNSSATSADLSFLPDQPSPAVAQETTKGLMNGRQSSIEAKDDDLLPIGSHVPLTKVDKGKQRMSVKEDQVMRDAPASAPAIQRHKNVFSGDREVTHVSSTPRPRTANPNDAGSSKDESRSHNGRSVSNITPTSQTTTRNSVLSEGKRVSAVKLWQNEFIAETPPRNLAAPAKTATQHPAVRRSLPVSFDSATPLASMPSMEAQRSGTPRSTLSASTQAHRVKKPRYETEEERKKRKMMAKLEKMAKEGRLAPPLSSMPRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q600</accession>
    <name>E3Q600_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_01392</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090268.1">
        <property type="nucleotide sequence ID" value="XM_008092077.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3Q600"/>
    <dbReference type="GeneID" id="24406757"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01392"/>
    <dbReference type="eggNOG" id="ENOG502QQWJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003023_0_0_1"/>
    <dbReference type="OrthoDB" id="2015333at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04043">
        <property type="entry name" value="C2_Munc13_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052811">
        <property type="entry name" value="Glucose_resp_signaling"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010439">
        <property type="entry name" value="MUN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014770">
        <property type="entry name" value="Munc13_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014772">
        <property type="entry name" value="Munc13_dom-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47263">
        <property type="entry name" value="ADENYLATE CYCLASE ACTIVATION PROTEIN GIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47263:SF1">
        <property type="entry name" value="C2 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_7G02350)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06292">
        <property type="entry name" value="MUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51258">
        <property type="entry name" value="MHD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51259">
        <property type="entry name" value="MHD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MHD1" evidence="3">
        <location>
            <begin position="689"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="2">
        <location>
            <begin position="898"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="domain" description="MHD2" evidence="4">
        <location>
            <begin position="1109"/>
            <end position="1230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="345"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ26248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1370" mass="156529" checksum="6339CB5F2129E40C" modified="2011-01-11" version="1">MSSASRSSWMPGRRPNSNRISMRPRGASRGNITVSHDDAYTFALRVAYLNYLLQPRQKRKQYVAAPKPAQRSHTSVTELVGQFVSSGSNSIKLPHGFQKPLEKRLKNVLTGKEPMQGFNDSALKRSFAEAYTAFTDKNFQKSVEKDRKLEPYVLMFYSSATKANQKYAQLTSATDDSWKETADRHMAMFIRLVAQTLRDQGHDRDRPELMSRLHTLENKLLTRDQNLSLDSAGDGGSYIEVPAPLSYDVKDMPLVLTVARIFGRSNSEVQADLEANRQVWTEENAIKDMKNYQQRLASDAPGALRSQDFDLEDAFQEWKRAEAPHLSQIILEILTIKPELAKTSTAGADKSLPGRPQSTFFGEDQSYSEISKSISSPDGSIMNFDSSIDSLSLDDSNQAFDEVVYTFVPNDSRAFYKAILKDCMTYDQLHADPAAEYTPLSQPSKDLLMELSVYWRLPQFSRLIAFIEVAVKKFLDGEILADDLLVVMDNAKSSEPERKKAPHLHQYNVGLREIDQSRWTMHDFAVYQKTLNSLYDALLRDLYNLMLNCYGPKPPNIGSVMTLLEEHVQSDPAFPARPEQVQEFAVHLTEGLRRAATDAYNVFVHEKLPNHASEWEFTHVVELGRAVTKLSNKIQKRYKNLPEIMGVKIWQILVEVMFPSYERDAQHIIERTIAVAKEKEMEINMQDGFDLYKELVEMRRTHHAALPDKPFEFQIEELLVDFVWRWVRNAENVMVEVVDGAISQDSFQVRTDDPNKIPTDAERHSTSVIDIFLMFHQTMEQVYQLEWDSDVHHARFMTALARSYAAGIGQYCDELEKRFAKEMDRPTAQEIAANKTAQEKFMQYAQYARDAWNPKDAPEPFQFLPESFVKLNNIEHAMQELDKLEKAMNVDACAEVLRKAEGLGKQQAKRPNKYVFTIKVVEAEDLKACDPGGFSDPYVVLGDEYQKRLYKTRIIHKNLNPRWDESVDITVSSPLNIIATIWDYDTFGDHDFVGRTSLKVDPIHFSDYLPREYWLDLDTQGRILLRVSMEGERDDIQFYFGKAFRHLKRTERDMVRKITDKLRAQISATISHETLRSLVRGGGIGSQVAGLWKKRASTMPTVTTASDIEGALQPLFHYFDQNFAIMKQTLTDATMLAVMTRLWKEVLQAIEHLLVPPLSEKPSSQRPLSQKELDIVYQWLNSLFEFFNAKDDSGEQLGVPQDVLKSPKWHELAALNFFYFEQTDNLIRESERMAAANAQRATQMLLQEKHENRLSAPATFGPTFSGGPGAFASMGTIRRGKSIMMSRNLGTMRKAKEEKRKEAQADPSDDMILRILRMRPEAANYLRERHRQKERQAAAAAAALIVKNSVNQGWNTGGASAYRANNLPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q634</accession>
    <name>E3Q634_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Wd40 repeat-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_01426</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090302.1">
        <property type="nucleotide sequence ID" value="XM_008092111.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q634"/>
    <dbReference type="STRING" id="645133.E3Q634"/>
    <dbReference type="GeneID" id="24406791"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01426"/>
    <dbReference type="eggNOG" id="ENOG502S1JP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073096_0_0_1"/>
    <dbReference type="OrthoDB" id="3267335at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178233" description="Wd40 repeat-like protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ26282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="299" mass="31459" checksum="0B1FF40C469DC516" modified="2011-01-11" version="1">MVRSSPISYTAALLYLFAASGSAQTFTISNGQIFTPGLVILDAPQPGTPLGGDNLHVALDVSTNGRMPLPPYAEDSPTKIFNVTMFLSSYVTGRNFTITNGTATANDASLGDIMFQEPGSTVKHVNWLWPDCLVGNGQPNSADSDRGAYNISIRQNFRLNGQDHYTIFDVPISVTNSIEEKDGRPSCDALNNALLTEEELNATAANAVGVLFAPGDSTNIQVEPDKGNGKGNDKGNDKGNDKGNDKGNDKGNNKDSGDALGRPKPEATPGDGLGAGNSLSWRSGAHWLCLVSIGAALML</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6Z1</accession>
    <name>E3Q6Z1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Ab-hydrolase associated lipase region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_02449</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090649.1">
        <property type="nucleotide sequence ID" value="XM_008092458.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6Z1"/>
    <dbReference type="STRING" id="645133.E3Q6Z1"/>
    <dbReference type="ESTHER" id="colgm-e3q6z1">
        <property type="family name" value="Acidic_Lipase"/>
    </dbReference>
    <dbReference type="GeneID" id="24407814"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02449"/>
    <dbReference type="eggNOG" id="KOG2624">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010974_5_1_1"/>
    <dbReference type="OrthoDB" id="9974421at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000095">
        <property type="entry name" value="Triglyceride lipase-cholesterol esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11005">
        <property type="entry name" value="LYSOSOMAL ACID LIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="24"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="10">
        <location>
            <begin position="139"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="486"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="619"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="491"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="560"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="638"/>
            <end position="648"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ26629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="648" mass="71927" checksum="A7EF91D50FB45897" modified="2011-01-11" version="1">MAIPFIGRLNIRDLELMALRSIEYLALVGSFLLVGLEAIIRVLTLALPSPLIHLFYRASRRLFHRFSAPANKRVEQPISTSVRDASDFVDLCHLYGYEAEEHVLQTKDGYLLGLHRLAWKKGEEGQKVNSGPGSLKKKVVYLHHGLLMNSEVWVCLTSEQRCLPFVLAEQGYDVWLGNNRGNKYSKKSVHHSPKSPEFWNFSIDEFAFHDIPDSIAYILGTTEQESLSYIGFSQGTAQAFATLAIHPKLNQQVNVFIALAPAMSPAGLSNGIVDALIKASPQVLFLLFGRRSILSSATMWQSILYPPIFVRFIDMGLSFLFNWQTKNITLSQKFAAYPHLYSFTSTKSVVHWFQIIRNKSFQMYDDDVHPPVSISSSSKYTKVAKYPTRNIKTPIVLVYGGSDSLVDIKVMIKELPPQTVATEIPHYEHLDFLWGRDVDAQVFPHVFDALDSFTDALHTKEEYDRYQLARQESLLGSGNAYTKHAYKESDVSASDTSNTADEGQNGNGLDTSSPQNKTRDRPSAIPSPHHTTRMRTPYSQVVNEDGSPSPSPDRPSSRAAEGEERPDSPLDMRDSPTAKLKGIGVRRGSGGSHLSLDSMREGRGISLGTSKALGGVVTKSPIDAKGLGNAKADENKSGKKKKRVTVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7J9</accession>
    <name>E3Q7J9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Fungal specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_02657</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090857.1">
        <property type="nucleotide sequence ID" value="XM_008092666.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7J9"/>
    <dbReference type="STRING" id="645133.E3Q7J9"/>
    <dbReference type="GeneID" id="24408022"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02657"/>
    <dbReference type="eggNOG" id="ENOG502QR1M">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007003_0_2_1"/>
    <dbReference type="OrthoDB" id="2123952at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF4">
        <property type="entry name" value="CONIDIAL DEVELOPMENT PROTEIN FLUFFY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="66"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="152"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="11"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="207"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="229"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="264"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ26837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="826" mass="90786" checksum="8CB4D6BF584CDB87" modified="2011-01-11" version="1">MEEAPGNEQQAQPSAGSASSAGASATSAPAPAPLASAAPTPSASGSSGAGQLSKRRRGLGVVTPNACTECRKKRAKCDGQKPCGRCKAQKDVECVYEVPVRQSKEHLRSEIEQLRYRQRSSDQVIAALVRSDMWEDVLQRLRSGQSLESVSEWLGGTLPSGGGSRTSLNRPPEQAGDANMGSGARPGFPGSTPAPIRTRNLGGPGSVTMSPITGQSNLRQDIDSNSPWHLSSHSQSTRSNSHPDVMNWSTDTNKPPQGLFDTWGESTSNTETSEGGSKYQGLDQVLAPLEPPYMKLPPEDWTNITDDGSLVQHLLALYFCWEYPTFASLSKEHFLRDFQNGVHRYCSPILVNALLALGCRFSSKSSTRANPSDPYTSGDHFFKEAQRLFYLEENHHNLTTIQALGIMSIREASCGRDSESWYYAGQSIRLAIEMGLHQLEEDGDDDEFAVQAATFWGAFALDHAWSLATGSLPQCSCFPHLPPKPAIIDDIEASLWIPYTDDGAPLQRSAEQPSNVRSVYKCFCELSELVHQSLYVLHSPGRPLTSRDLLGIYTQYLNWYDRIPEVLRLGHNFTPAVLFAHMYYHFAILLLFRPLIKLRIIGSKLLPRDVCGQAADAIQGLLRSYSQLYTLRRTPSFVPYFVLTSSIMHLAIGAACAPPQKGFDATAPASVDPAAQPPYPPRVVEAIKQGIRDLEEMAPCHHFAEQALNILRYLAKKWNLDVDMGERLPSDAEYAHLVRPYTSSLNFFAPNVIEDDFICTWGGSTDEAETPNPATTMGTKGIEPGKPSVSRAAKVLENPLFWPFPMQGRPMLPTGRELKDAGFERI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q868</accession>
    <name>E3Q868_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_02251</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091100.1">
        <property type="nucleotide sequence ID" value="XM_008092909.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q868"/>
    <dbReference type="STRING" id="645133.E3Q868"/>
    <dbReference type="GeneID" id="24407616"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02251"/>
    <dbReference type="eggNOG" id="ENOG502T4JS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_576187_0_0_1"/>
    <dbReference type="OrthoDB" id="4777753at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="413"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ27080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="442" mass="50372" checksum="9D94CFEED71E638F" modified="2011-01-11" version="1">MGNKRARVITENQKYNDGKVNTGIVDPSTRSLSHIKRHINFEVPQEIDTQYFRNNLLAQGIVHRCTIRSLLETQNLSEEQKDRLQQTSLPKKNRLATVYHAGAISAPDFAQKNIAFAEAFGDFLLHENPKGLADFAPLAKLKDQALRRAKDQQATQPKREDEPAIAMGSIEKTGSGNSALMPLVTRREVWMSLCPNRKCVGGFPFEVPIPAAVRLQKHVIEELENETNSYTGRGEDAIQRDEGSLANYIHPHVRIDVAQRKLPDGRSIHVLLLGLVEDTYNLRFSRLGLLQAYDMVVCWASRIDSDGISISLKSAFDGCNQITEFIVAGSDRINELAVLERRLERFMPDISQFDEAVERISQWMERRKAKLVSSPEDRERRLRKWCEKQKLGDMGNDLLEQACQQAVEVKTREWKKSTQRNKRARFDDVIDGAQPTKRRRKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8F0</accession>
    <name>E3Q8F0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Hsp90 chaperone protein kinase-targeting subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_02333</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CDC37 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091182.1">
        <property type="nucleotide sequence ID" value="XM_008092991.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8F0"/>
    <dbReference type="STRING" id="645133.E3Q8F0"/>
    <dbReference type="GeneID" id="24407698"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02333"/>
    <dbReference type="eggNOG" id="KOG2260">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033261_0_0_1"/>
    <dbReference type="OrthoDB" id="440202at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031072">
        <property type="term" value="F:heat shock protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050821">
        <property type="term" value="P:protein stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.610:FF:000002">
        <property type="entry name" value="Hsp90 co-chaperone Cdc37, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.610">
        <property type="entry name" value="Cdc37, Hsp90 binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004918">
        <property type="entry name" value="Cdc37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013873">
        <property type="entry name" value="Cdc37_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013874">
        <property type="entry name" value="Cdc37_Hsp90-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038189">
        <property type="entry name" value="Cdc37_Hsp90-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013855">
        <property type="entry name" value="Cdc37_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12800">
        <property type="entry name" value="CDC37-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12800:SF4">
        <property type="entry name" value="HSP90 CO-CHAPERONE CDC37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08564">
        <property type="entry name" value="CDC37_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08565">
        <property type="entry name" value="CDC37_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03234">
        <property type="entry name" value="CDC37_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01069">
        <property type="entry name" value="CDC37_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01070">
        <property type="entry name" value="CDC37_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01071">
        <property type="entry name" value="CDC37_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101391">
        <property type="entry name" value="Hsp90 co-chaperone CDC37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cdc37 N-terminal" evidence="9">
        <location>
            <begin position="2"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Cdc37 Hsp90 binding" evidence="8">
        <location>
            <begin position="197"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="Cdc37 C-terminal" evidence="7">
        <location>
            <begin position="376"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="182"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="456"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="184"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="201"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="217"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ27162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="476" mass="53339" checksum="FDD620CA08627B4E" modified="2011-01-11" version="1">MPVDYSKWDALELSDDSDIEVHPNVDKRSFIRAKQNQIHQERLQRKHQIETLKYERIINDGLIRRISNLLDALKSHASEAETRNPGEVAFRAVMESAGKPEDDQPPPRPEGIHADSEPLPTFSKMMAVLLDQVNKELDEKKPENRYQAMLEGVEGHLTKVQNLQKELFAKLAELEKEEGRKITSESIHTGFDSSHVNKSQDTGKKEERKPELLNPNFDMTQSIPAKSTASHNDDEEIEASPAAKAFAQIKADDYTSSLSYLSKNPQILTERETDGLLVLAFDAALEGKDDYCRQCVHQALLLQYCRALGKDGVGMFFKRITTRGHQAQEVFYKDVQDTYGKIRNRAREIVKERANEPEGVEQIQLHAVEPGTEIKITIPPKDSEDPATKQGREIFESFSPDFQRALESGSLDKVNEVLGKMKVDEAEDIVGKLGDAGILSLEEQIIDATTEEGQKALKDMEAAQAGSESGFAADPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8Q2</accession>
    <name>E3Q8Q2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fungal specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_01911</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091436.1">
        <property type="nucleotide sequence ID" value="XM_008093245.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8Q2"/>
    <dbReference type="STRING" id="645133.E3Q8Q2"/>
    <dbReference type="GeneID" id="24407276"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01911"/>
    <dbReference type="eggNOG" id="ENOG502SH59">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010508_0_0_1"/>
    <dbReference type="OrthoDB" id="424974at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF1">
        <property type="entry name" value="MISCELLANEOUS ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="29"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="55"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="362"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="57"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="76"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="366"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ27416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="775" mass="85597" checksum="AE087DCC7D5EE9B5" modified="2011-01-11" version="1">MTGSVSSSGEQPSVSGNQSHSKRIRLSLACNQCRKRKVRCDAQTPKCHNCILRGDDCQTTNPRNPNQHAVRKWAAKSNTNQSEGGSTYETSETPREQSHYRTASPRARQYLSPAYDDGSEGEAAASQKMSWVARAYRANARDNQSPHEHADLNPDMALNTDESPHRLKFMGGSSVQSLTMFADLFFRKRGLKPISPYFRFGMHHVEEYQVPLSFQLPSLPPLPTMDAYLDVYMKRIFPLFPVFDEPTLRSELGRLTTLQDSDSSAGLQNLIEPSQVPLLVCIYSIMCIGADEETCMLTEVGTHYLTAAYSLLAHVISTPYLASVQALVLLTIALRGRSKEGQGWQTLGQAIRIAHSIGLHRHASTRHSGNTPDAGNSVPSPGYQADRKLHSRVWWACYNLEKLMELETGRPAAIHDSDCDHRLPDPVPIPSAGIFSLSASESLHNRQTLDYFQPWTSLSRIISSVSAHIYRRSGQSQTSRILLGDTVRLDSALTEWAQSLPPEIRPPGPNSGNEILCETGHKHLTIFLAIQYHHALISLHRAALVFPESMYRTHINYQADCGTLSAVELTRLRRGAEICIGSARTIVRLIGEIADDSTPTPRPRGGMLGEAPHTKSESIIFTITQPLMAAVALALHILKQPSSRLARSDLELLGIAAQYAEEQYTKVSQNPRFIQACSVLQSNMSEIVSGHRQHRGSTNSIAVESVRHEHALVADSNPEAISSAMDMMDFELPDLTGMFTEISNTDLFGGVRLENLWGMLGAEGQFGKGSGSWPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q8W1</accession>
    <name>E3Q8W1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_01970</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091495.1">
        <property type="nucleotide sequence ID" value="XM_008093304.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q8W1"/>
    <dbReference type="STRING" id="645133.E3Q8W1"/>
    <dbReference type="GeneID" id="24407335"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01970"/>
    <dbReference type="eggNOG" id="ENOG502QRFX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_42_5_1"/>
    <dbReference type="OrthoDB" id="10264707at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052742">
        <property type="entry name" value="Mito_N-acetyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015416">
        <property type="entry name" value="Znf_H2C2_histone_UAS-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43138">
        <property type="entry name" value="ACETYLTRANSFERASE, GNAT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43138:SF2">
        <property type="entry name" value="PROTEIN SPT10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09337">
        <property type="entry name" value="zf-H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="123"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="374"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="414"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="516"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="528"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ27475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="550" mass="60489" checksum="4BF020AA9B1B1B66" modified="2011-01-11" version="1">MPAMLDDPTSPTIYRVSGAPPYPDPDKPELPIDIVPRQVTLRDRQTTATIIPFASQNEVPQSLVRYLSDQLNKEIEGGDTYPMMDPMPAGKFGAYWFQNFGAIMLLGNMERAALTDDMDWSRECLGSFYIKPNYPGRSSHVCNAGFLVTDASRNRGVGRLMGECYIDWAPKLGYTYSVFNLVYETNVASCKIWDALGFKRIGRVKGCGNLKSHPGQLIDAIIYGRDLIPGESEELVSEERFDKIKFYLKYGKYPAGADRAEKSRLRSAATHYKLLDDDRLMLKDKEVVPDPRRQYEIAREVHVAQHGGINKTTATIAEKYHWSRIKETVSDVIRNCVECKELSKMPASGGNGGARGRAAAVAAAAASSSLANISTPISNTSLSNPSFTSTSASTPPPSAADVSTANGVLALQHHLSPLSPPRPSPYAEVASIPPSHTLRDPSASPLPRHPHHNPMLQDESFQPIDPQIIGPPPTSHDDPYNHYHPHHTDFQALLNATEAEETAEEAAAVDRDLDMLIEQGDDEDERDGDVPMGEKDGRDKDVYSIGFING</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q964</accession>
    <name>E3Q964_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10 11">Endo-1,4-beta-xylanase</fullName>
            <ecNumber evidence="4 10 11">3.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_01738</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10 11">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-xylosidic linkages in xylans.</text>
            <dbReference type="EC" id="3.2.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10 11">Glycan degradation; xylan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10 11">Belongs to the glycosyl hydrolase 11 (cellulase G) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.8" evidence="4 10 11"/>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091263.1">
        <property type="nucleotide sequence ID" value="XM_008093072.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q964"/>
    <dbReference type="GeneID" id="24407103"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01738"/>
    <dbReference type="eggNOG" id="ENOG502RXA7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052631_0_0_1"/>
    <dbReference type="OrthoDB" id="2115822at2759"/>
    <dbReference type="UniPathway" id="UPA00114"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031176">
        <property type="term" value="F:endo-1,4-beta-xylanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.180:FF:000001">
        <property type="entry name" value="Endo-1,4-beta-xylanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013319">
        <property type="entry name" value="GH11/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018208">
        <property type="entry name" value="GH11_AS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033123">
        <property type="entry name" value="GH11_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001137">
        <property type="entry name" value="Glyco_hydro_11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46828:SF3">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46828">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00457">
        <property type="entry name" value="Glyco_hydro_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00911">
        <property type="entry name" value="GLHYDRLASE11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00776">
        <property type="entry name" value="GH11_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51761">
        <property type="entry name" value="GH11_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8 10 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 10 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10 11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="5 10 11" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179531" description="Endo-1,4-beta-xylanase" evidence="12">
        <location>
            <begin position="20"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="GH11" evidence="13">
        <location>
            <begin position="35"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="121"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ27243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="225" mass="24047" checksum="1FA7FA2D61706EC4" modified="2011-01-11" version="1">MRSFTSLFTATLAAVGALAAPAAEPPMTTDLIKRASTPSSTGTNNGYYYSWWTDGASPVTYTNGAGGSYSVQWQSGGNFVGGKGWKTGGARTIKYSGNFSPVNNGNAYLTVYGWTRNPLIEYYIVENHGGYNPGSAGTLKGQVTADGSVYKLYQATRVNAPSIDGTKTFQQYWAVRENKRSSGSVNTQTFFDAWKKAGMNLGTHDYMIMATEGYKSAGSASITVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9A6</accession>
    <name>E3Q9A6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_01780</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091305.1">
        <property type="nucleotide sequence ID" value="XM_008093114.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9A6"/>
    <dbReference type="STRING" id="645133.E3Q9A6"/>
    <dbReference type="GeneID" id="24407145"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01780"/>
    <dbReference type="eggNOG" id="ENOG502SX45">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_657220_0_0_1"/>
    <dbReference type="OrthoDB" id="4222821at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001080">
        <property type="term" value="P:nitrogen catabolite activation of transcription from RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF4">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN DAL81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="8"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="291"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ27285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="496" mass="54338" checksum="218364D55BB7629C" modified="2011-01-11" version="1">MLFSQRSACDRCRALKSRCSRENGAKKCERCQRLQIDCFYSPPRRMGRPAKKRLSQEVTTQSTPPVQYRRLSTMSNTTLQTAQSEGFSPSVTEAEDFQYGLGIMPSPSAGGGGHEWTDNFEDPLLGFLQEHNTKLMATNWMNTGSLGFLGHHENALAAGPHDLPLTPTTVGSLPNNTDDSWTSGSDQGPAICHAESYTGATLPPSPDINVGSSEPAIKRLLDLQSLLIARRIATSQEQEDLSTLINTTVHATETLIDVVESLPPLRPSPEATQPASPVSCWGQALDAGPFNTSAPTHAAPELHDPHQQQGQRQQYPDLALTISLFTTDHLLLLDSYDNLLVALRARLQCPRQSRPPSPGGDFNLPQHFFNNASGGPLNKFSLVSSFDLDINSVVFLLSRMMKRLQKSMQDRFTYGPVASTSDAQLKGRGFPFSNASLNFNFQDGVSHNLDVASELSPTGGHPPIANMGDYASWEASKRHQNVTESLRVIRWLADEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9P6</accession>
    <name>E3Q9P6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 5B</fullName>
            <ecNumber evidence="3">3.6.5.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Translation initiation factor IF-2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">GLRG_02728</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.3" evidence="3"/>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091604.1">
        <property type="nucleotide sequence ID" value="XM_008093413.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9P6"/>
    <dbReference type="STRING" id="645133.E3Q9P6"/>
    <dbReference type="GeneID" id="24408093"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02728"/>
    <dbReference type="eggNOG" id="KOG1144">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002656_1_0_1"/>
    <dbReference type="OrthoDB" id="4928at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03703">
        <property type="entry name" value="aeIF5B_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01887">
        <property type="entry name" value="IF2_eIF5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000013">
        <property type="entry name" value="eukaryotic translation initiation factor 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000026">
        <property type="entry name" value="Eukaryotic translation initiation factor 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10050:FF:000002">
        <property type="entry name" value="Eukaryotic translation initiation factor 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000112">
        <property type="entry name" value="Eukaryotic translation initiation factor 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10050">
        <property type="entry name" value="Translation initiation factor IF- 2, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029459">
        <property type="entry name" value="EFTU-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015760">
        <property type="entry name" value="TIF_IF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023115">
        <property type="entry name" value="TIF_IF2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036925">
        <property type="entry name" value="TIF_IF2_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003078">
        <property type="entry name" value="PRK04004.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381:SF4">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14578">
        <property type="entry name" value="GTP_EFTU_D4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11987">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52156">
        <property type="entry name" value="Initiation factor IF2/eIF5b, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 16" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="15">
        <location>
            <begin position="480"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="297"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="22"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="111"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="160"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="211"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="305"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="375"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="422"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="453"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EFQ27584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1075" mass="118276" checksum="DBD6F8F9F8B81B4C" modified="2011-01-11" version="1">MPPKKKGNKARADDDWEKELGETIAPAAAETSETAAEKPAEEDENEAPTGLMATMRKNREKRKKKGIEEPPAAPEPEAEPSPSLAEKAPQEATMEDEFALPEKKGKGGKGKQAAAAAAAPAAGDEDDGSGRVLTKAEKEKLKKEREKQRKKEQAAKKKGPAPAAKAEPAKAAPEKKDSPTPAASAVAPPPAEEKGGKKKKIPAALAALQKQQEELRRQQEEQARMAEEEKKRIEEEERAMEEERKQREEAKALKKQKEKEKIEQLKKEGKFLTKAQKEEKARNERKLQQMLAAGIKVGPADEGEGDKKKKVVYDNKKKGGRKAQDKIDEEKALAEAAERAKKEAERLHREAEEKAAKEKAEAEAAAAKKKAAEASDLEDDWEAAAASDEEDVKDSWDADSDEEQEKKKAANGKPTEPVEKSENDEDEDDDSGSDSESDSSEEDEKETAARQAELQRKREAAERREKAHQAALAAQSKDNLRSPICCILGHVDTGKTKLLDKIRQTNVQEGEAGGITQQIGATYFPVEAIRQKVAVVNKDGSFEFKVPGLLVIDTPGHESFSNLRSRGSSLCNIAILVVDIMHGLEPQTLESMRMLRDRKTPFVVALNKIDRLYGWKKVDNNGFQESLALQPKGVQNEFKNRLEQTKVAFAEQGFNSELFYENKSMARNVSLIPTSAHTGEGIPDMLKLIIQLTQERMVGSLMYLAEVQATVLEVKAIEGFGMTVDVVLSNGILREGDRIVLCGVEGAICTNIRALLTPAPMRELRLKSAYVHNKEVKAALGVKISAPGLEGAIAGSRMLVVGPDDDEDDIIDEVESDLATLFSRVEKTGRGVSVQASTLGSLEALLDFLKDCKIPVANVGIGPVYKRDVMQAGIMLEKAPDYAIMLCFDVKVDKEAQQYADDVGVKIFTADIIYHLFDAFTKHMAELLEKKKEESKMLAVFPCVLNTVAVFNKTNPIVVGVDVVDGQLKINTPIAVVKNNAVTGMKEVINLGRVTSIERDHKQIPVCKKGQPSVAVKIEMGGHQPTYGRQLEESDTLYSLISRASINTLKEFYRKDVSNDEWNLIIKLKPLFDIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9U6</accession>
    <name>E3Q9U6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Spindle pole body component</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_02778</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
            <location evidence="5">Cytoskeleton</location>
            <location evidence="5">Microtubule organizing center</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TUBGCP family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091654.1">
        <property type="nucleotide sequence ID" value="XM_008093463.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9U6"/>
    <dbReference type="STRING" id="645133.E3Q9U6"/>
    <dbReference type="GeneID" id="24408143"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02778"/>
    <dbReference type="eggNOG" id="KOG2001">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007738_0_1_1"/>
    <dbReference type="OrthoDB" id="2192946at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000930">
        <property type="term" value="C:gamma-tubulin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044732">
        <property type="term" value="C:mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043015">
        <property type="term" value="F:gamma-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051011">
        <property type="term" value="F:microtubule minus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051225">
        <property type="term" value="P:spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1900">
        <property type="entry name" value="Gamma-tubulin complex, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007259">
        <property type="entry name" value="GCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040457">
        <property type="entry name" value="GCP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042241">
        <property type="entry name" value="GCP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041470">
        <property type="entry name" value="GCP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302">
        <property type="entry name" value="GAMMA TUBULIN COMPLEX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302:SF13">
        <property type="entry name" value="GAMMA-TUBULIN COMPLEX COMPONENT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04130">
        <property type="entry name" value="GCP_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17681">
        <property type="entry name" value="GCP_N_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3 5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma tubulin complex component protein N-terminal" evidence="8">
        <location>
            <begin position="218"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="domain" description="Gamma tubulin complex component C-terminal" evidence="7">
        <location>
            <begin position="558"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="873"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="30"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="55"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="101"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="117"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="129"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ27634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="966" mass="108841" checksum="BB7BB13D175605C0" modified="2011-01-11" version="1">MSSGTRVSTHERRATSGTAPAADQERASRAARMNAAAAAAGAAGNGTESAQTSFKSERSERSDARQRERDREREQRRDRAASPGNHAHKRSASGNPRTASRTHDDRRVEERRTERTYVTQLETMVQRTRSPERGERRGGGDKGKATEAKLRAAEAKPKEPKVDGPPAPWNPEATLLPHTSAPLACRISIPPLASQAPQPQQPKPLNELPLEAQEAVMLEDLLFVFMGYEGQYIRFVKTYNPHEERDRLSGPAFRILPGLDPSLQDLTVSMLKMATYYSALEMFVDVQSRDEFGAVNHALCASIRKFLHDYLVMIAQLETQFLTNETFTLHVLNIHTLPTCQMMSHLYSLAHDLLKRNALLDEDDDEEESDSADDFENILESLREGGDLAPGSGKKICKGGVVLGLITKRLESMSGDPAARALLTTLLRDASKPYMVMLNEWLHHGGINDPHAEFLIKEQKSIRRERLEQDYTDEYWERRYTIREHDIPPQLEGVKEKVLLAGKYLNVVRECGGVDVSKVVQDVPTSFDDSRFLENVNSAYAHANESLLQLLLTTHSLPMRLRSMKHYFFLDPSDYFSYFLELGTSELRKPVKSVNTGKLQSLLDLVLRQPGSIVSLDPFKEDVKVEMNEITLIKSLQRVVNITGIEQGETLQPLANQPIENDRNAIGFTSLQLDYTVPFPVSLVISRKTVWRYQALFRYLLSLRYLESQLSTTWYSQTSGLTWAHKSSSRSLEIWKRRVWTLRARMLVFVQQLLYFCTAEVIEPNWAKFMSRLKVGEEGQEAASGGVSSGPTRTVDELMQDHVDFLDTCLKECMLTNSKLLRIHSKLMQTCTIFATYSNWLSRELEKADPDLSGATRPPNMTPEQWRAFQAVRTQKPTTGSHSDSTSSAGPGASDQQQQDARVGNLFEIMKKWESNFSRHLQILLDALNHYAATETVVLLSLCARLSTANQGTEYSGLRNEDDSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9X9</accession>
    <name>E3Q9X9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_02811</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091687.1">
        <property type="nucleotide sequence ID" value="XM_008093496.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9X9"/>
    <dbReference type="GeneID" id="24408176"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02811"/>
    <dbReference type="HOGENOM" id="CLU_1885606_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ27667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="135" mass="15602" checksum="BD58E7C8ED14951E" modified="2011-01-11" version="1">MRRPARQLEQQVAYDGTRHLQGNGSNKRWEPRQENYSDQCLAGREQAELVWEGYFLDCVVWGIEKCPSRALLASQRIRDCNVVSLLFAGCIDWEIELQMKQYFIPPAIGQDLAATERAFKADSDASQHRYSYDVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>E3QA01</accession>
    <name>E3QA01_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Eukaryotic translation initiation factor 2 subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_02833</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF2B.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eIF-2-alpha family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091709.1">
        <property type="nucleotide sequence ID" value="XM_008093518.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QA01"/>
    <dbReference type="STRING" id="645133.E3QA01"/>
    <dbReference type="GeneID" id="24408198"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02833"/>
    <dbReference type="eggNOG" id="KOG2916">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033458_0_1_1"/>
    <dbReference type="OrthoDB" id="1685042at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005850">
        <property type="term" value="C:eukaryotic translation initiation factor 2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043614">
        <property type="term" value="C:multi-eIF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990856">
        <property type="term" value="F:methionyl-initiator methionine tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001731">
        <property type="term" value="P:formation of translation preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd04452">
        <property type="entry name" value="S1_IF2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1130:FF:000001">
        <property type="entry name" value="Eukaryotic translation initiation factor 2 subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000015">
        <property type="entry name" value="Eukaryotic translation initiation factor 2 subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.190:FF:000002">
        <property type="entry name" value="Translation initiation factor 2, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1130">
        <property type="entry name" value="EIF_2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.190">
        <property type="entry name" value="Translation initiation factor 2, subunit 1, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044126">
        <property type="entry name" value="S1_IF2_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024055">
        <property type="entry name" value="TIF2_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024054">
        <property type="entry name" value="TIF2_asu_middle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011488">
        <property type="entry name" value="TIF_2_asu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10602">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10602:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07541">
        <property type="entry name" value="EIF_2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110993">
        <property type="entry name" value="eIF-2-alpha, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116742">
        <property type="entry name" value="eIF2alpha middle domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 12" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="S1 motif" evidence="11">
        <location>
            <begin position="20"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="285"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="297"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00060206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ27689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="311" mass="35333" checksum="20F137C10A092F4F" modified="2011-01-11" version="1">MAEPNYSHFRYFENKYPEIDEFVMVNVKQIAEMGAYVKLLEYDNIDGMILLSELSRRRIRSIQKLIRVGRNEVVVVLRVDKEKGYIDLSKRRVSPEDIIKCEERYNKGKMVHSIMRHVAEKTLTPIEQLYETIAWPLNKKYGHAIDAFKLSITNAEVWNDATFPSEAVSEELKSYIAKRLTPQPTKVRADVEVTCFGYEGIDAVKAALRTAEARNDDQTQVKVRLVSPPLYVLTSTCLDKNLGISRLEEAIVEIRTSIEAAGGSLVVKMEPKAVTESDDAELQALMEKRERENAEVSGDESVSESDDNPEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAH9</accession>
    <name>E3QAH9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Phospholipid-transporting ATPase</fullName>
            <ecNumber evidence="19">7.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">GLRG_03011</name>
    </gene>
    <organism evidence="24">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.</text>
            <dbReference type="EC" id="7.6.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66132"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:66133"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 18">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endosome membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="19">Membrane</location>
            <topology evidence="19">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 19">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.1" evidence="19"/>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ27867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091887.1">
        <property type="nucleotide sequence ID" value="XM_008093696.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QAH9"/>
    <dbReference type="GeneID" id="24408376"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03011"/>
    <dbReference type="eggNOG" id="KOG0210">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000846_6_0_1"/>
    <dbReference type="OrthoDB" id="377733at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140326">
        <property type="term" value="F:ATPase-coupled intramembrane lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000048">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000067">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000009">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006539">
        <property type="entry name" value="P-type_ATPase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032631">
        <property type="entry name" value="P-type_ATPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032630">
        <property type="entry name" value="P_typ_ATPase_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01652">
        <property type="entry name" value="ATPase-Plipid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092:SF5">
        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16212">
        <property type="entry name" value="PhoLip_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16209">
        <property type="entry name" value="PhoLip_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 17 19" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9 18 19" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 17 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 19" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 19" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="241"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1147"/>
            <end position="1166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1191"/>
            <end position="1213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1225"/>
            <end position="1243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1250"/>
            <end position="1272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1278"/>
            <end position="1302"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase N-terminal" evidence="21">
        <location>
            <begin position="186"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase C-terminal" evidence="22">
        <location>
            <begin position="1084"/>
            <end position="1311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="1"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="283"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="395"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="20">
        <location>
            <begin position="18"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="46"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="142"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="16">
        <location>
            <position position="648"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="648"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
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    <feature type="binding site" evidence="18">
        <location>
            <position position="648"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="649"/>
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        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
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    <feature type="binding site" evidence="17">
        <location>
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        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
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    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="650"/>
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        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="761"/>
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        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="805"/>
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        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="839"/>
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        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
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    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="868"/>
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        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
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    <feature type="binding site" evidence="17">
        <location>
            <position position="949"/>
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        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
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    <feature type="binding site" evidence="17">
        <location>
            <position position="950"/>
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        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
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            <position position="951"/>
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        <ligand>
            <name>ATP</name>
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        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="1031"/>
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        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
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    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="1037"/>
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        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
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        <location>
            <position position="1057"/>
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        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
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        <location>
            <position position="1060"/>
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        <ligand>
            <name>ATP</name>
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    <feature type="binding site" evidence="17">
        <location>
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        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
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            <position position="1061"/>
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        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00034036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU362033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF16209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF16212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="EFQ27867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1320" mass="145727" checksum="86CCAC23DD1F783B" modified="2011-01-11" version="1">MPSPSSYRSADPPGSPENESDSDLDLDIQELDPATTSTERTSGLLRQDRQNTEHRSPRIALRNLRMGGSRRAGQKARGYGELGQNRDGANEDAEALLAEAEGSSSRYGDGTTGAGSDDDSPLLPGGSPPRRRSFTGDRFGRLTSSLRLPSFMSNPGVQEANKDDGQDQDEDDPSSSRLVAVGSAQATRFPPNLVSNAKYTAFTFLPVTLYNEFSFFFNMYFLLVALSQAIPALRIGYLTTYVAPLAFVLVITMGKEAYDDIERRRRDNEANAEAYTVLTFDEPGRGMAPGRRSHKRLKSDSMRVKGKNSVNHRDRLSDIQEEEERAEGDGPVAEPSSVVREVSRKSRDLKVGDVLKLTKGQRVPADVVILKCITSETTNAPPAMEVIVEEESLLVDTEDEEPKNAKLPTKGKEVENSDNGGGATGETFIRTDQLDGETDWKLRLASPLSQTLPTEEFVRLHVTGGKPDRKVNEFLGTIELMPSQRGALNQQGALDGGENTSAPLSIDNTAWANTVIASNATTLAVIMYTGPQTRSALSTAPSRSKTGLLEYEINSLTKILCALTLALSIILVALEGFENTEGNVWYIKIMRFLILFSTIVPISLRVNLDMGKSAYSWFIQRDPGIPGAVVRTSTIPEDLGRIEYLLSDKTGTLTQNEMEMKKIHVGTVSYANEAMDEVTSYVKQGFHIPLTTDPSSHTMLMTPSTAFSNSANVGATRTRREIGSRVRDVVLALALCHNVTPTTEEEDGKTVVSYQASSPDEIAIVRWTESVGLRLAYRDRTNMILESTENGREIVRVRILDVFPFTSEGKRMGIIVQFFDHAQSTAPNLANSEIWFYQKGADTVMSPIVAENDWLDEETSNMAREGLRTLVVGRKRLSYEQYKEFTGSYQAASLAIAGRDASMQRVVAQYLERDLELLGVTGVEDKLQKDVKPSLELLRNAGIKIWMLTGDKVETARCVAVSSKLVARGQYIYTVSKLKKKDNAQDHLDFLRGKTDSCLLIDGESLALFLTHFRIDFVSVAVQLPTVVACRCSPTQKAEIAKLIKEYTKKRVCCIGDGGNDVSMIQAADVGVGIVGKEGRQASLAADFSIEQFFHLTKLLVWHGRNSYKRSAKLAQFVIHRGLIIAVCQTMYSIAIKFEPEGLYKDWLLVGYSTVYTAFPVLSLVLDKDVDENLANLYPELYKELTSGRSLSYRTFFVWVAVSIYQGCTIQGLSQILTEVDGPKMVAVSYTVLVLNELLMVAIEITTWHPVMIITIVGTFVAFVGSIPFLGGYFDLEFIITLGFIWRVLAIAAISLIPPYAVKLIRRTMKPPSYRKVQST</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAM2</accession>
    <name>E3QAM2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal L5P family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_03054</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL5 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ27910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091930.1">
        <property type="nucleotide sequence ID" value="XM_008093739.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAM2"/>
    <dbReference type="STRING" id="645133.E3QAM2"/>
    <dbReference type="GeneID" id="24408419"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03054"/>
    <dbReference type="eggNOG" id="KOG0398">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061015_1_0_1"/>
    <dbReference type="OrthoDB" id="539541at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002132">
        <property type="entry name" value="Ribosomal_uL5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031309">
        <property type="entry name" value="Ribosomal_uL5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022803">
        <property type="entry name" value="Ribosomal_uL5_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11994">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00673">
        <property type="entry name" value="Ribosomal_L5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55282">
        <property type="entry name" value="RL5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL5 C-terminal" evidence="5">
        <location>
            <begin position="246"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ27910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="349" mass="38894" checksum="D8BD0374849CE90B" modified="2011-01-11" version="1">MAALRETSQMTRAICRQRSPWQLSPFVIQRCSSTSTAKPELADLEPSSSLAAPGPDDAAVKAFDTAKRISERPQQLPGNRYQYHPPKFDRGPLHPIQSPPSTDPTARDFVPGPFNIPRLRQTYDATIASDLLTLTYLHKPPGTPEREVRERLRAWDDSSPYNKNRPLRGPRGGSKLDVLERNINWRSIPEIKAVSVHAFMPTAPKVPGTLHVARSIIQSISGNCPEVTKTKNNVIDWKIRKGDKNGVKTTMYGNQAYEFVDKLINLVLPKIKDWPGVNASTGDGNGGLALGLKPDDLAWFPELQINWDMYPAKLIPGCHIFIQTTATSNRQARLLLQALGLPFYGKFKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAN1</accession>
    <name>E3QAN1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_03063</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ27919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091939.1">
        <property type="nucleotide sequence ID" value="XM_008093748.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAN1"/>
    <dbReference type="STRING" id="645133.E3QAN1"/>
    <dbReference type="GeneID" id="24408428"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03063"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031576_0_0_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11070">
        <property type="entry name" value="CYP56-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF223">
        <property type="entry name" value="CYTOCHROME P450-DIT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="4 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="443"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ27919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="481" mass="54692" checksum="5B9EE6CBEF8FDA4E" modified="2011-01-11" version="1">MLLLLLEILLLGALLPGFVYYFFLLPPKYPQNIPAIPFWVALIPFFKDVDQSDIFLEYIDKPLRAHGAVKIFFGAQWNILVHRPSYLVEIFKDEDLYEKSGNQTKIPHSVLADFLGDNIISARGDVWKSYRSVIKPGLQRNFDACMIEANAVILCRLLRESQQRAGRGGVAVQDLLQRYSVSNFSEAVLGTRLHALDRADARINILQTAVKKEIFKPIFMSFPFLDRLPLKSRLAARHTVGLFKNELKRALQASHHLQKTPPLSEASYKLGKRMLDARASGLWDEKQLLDNLTVAFVAGQENPQLAMISTLYLLAKHPEAQELLRQEIVSKGVKSPADLTKEDMPYLTSLLYESLRLFPPIGQLINRKAARTALLGGNVVIPEGTYVGYHCYSTNRCPTAWGPTADQFNPGRWGCSSEAIQQEYRRRRARGEWISFHGGKRACLGEKFAMLEMRVTLIQLVREFFFTLDPTWVDRKTPVRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAN4</accession>
    <name>E3QAN4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_03066</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ27922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091942.1">
        <property type="nucleotide sequence ID" value="XM_008093751.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAN4"/>
    <dbReference type="STRING" id="645133.E3QAN4"/>
    <dbReference type="GeneID" id="24408431"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03066"/>
    <dbReference type="eggNOG" id="KOG1721">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028814_0_2_1"/>
    <dbReference type="OrthoDB" id="427030at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000774">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000072">
        <property type="entry name" value="zinc finger protein 143 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="239"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="269"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="299"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="327"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="113"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="393"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="457"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="137"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ27922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="491" mass="55733" checksum="40ABCEC1D83D5BCA" modified="2011-01-11" version="1">MALPEQTAAPQAWGRWQQQPAGHDYGMMDNSTFVQYDSRAATSAPMNGAIMAPQYMVAPQYNMTQMPAMGHQCPTQNHFAYTQYDSSPTNMNMPFRLPPQPERPVMPVAASEHDIPRASSYPQESPSVKNDRHRSPSSRSETKMSNPKTPHPLNTKEIKYNKPTSADPVNFTTAIDTLMKAIQKRNDSEDIVKGVPEIEQVVKPERMLSLEPEAGSIAPVQAPAPIATESTDAPKPKRYICDVEGCGKSFYQSTHLDTHRRAHTGEKPYQCNWPRCGRTFSQPGNLKTHMRRHTGEKPFRCEQCSKVFAQRGNLQTHMATHTNAKPFVCKLDDCNKMFTQRGNLKNHQNKYHEKTLMEMTDWIVSISDIDALSDDQREMYWYFANLYKNSNKGIKGRGKDRRVSNRGAKSRTAPSSYPVKRVPGPASLAAYSSKRLPPPEQYMQQQQHHQHGYEVYDTDMDQSSSASSPRYDGLPATYRDRMYQQSTHAMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QB87</accession>
    <name>E3QB87_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_03269</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ28125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008093954.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QB87"/>
    <dbReference type="GeneID" id="24408634"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03269"/>
    <dbReference type="eggNOG" id="ENOG502SAWI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011074_1_0_1"/>
    <dbReference type="OrthoDB" id="4150467at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="569"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="139"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="259"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="381"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="468"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="15"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="214"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="297"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="381"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="399"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="468"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="495"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="518"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="543"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="578"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ28125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="654" mass="69559" checksum="BEFD96BB6F03F7FF" modified="2011-01-11" version="1">MTSMSPASAVDGGSAATSNQGSVSPRQTVSPKNVAFELLFTESPQYRARLPMRVQIYPHDTTDSIVTTVKNFYGLYSGPTGSKGVSFEDENGITLIARYENFRNNMVVYVRVIEEPPSASGPFVAPAYHNPPLSAQPYYEGNAYPLQPPPRFGQEISRPSSSTSRRRSPSPNVGRGRRSGSANTNPKKGRSRSSKNRDTAANGHADIYSDSLNGYSSGDGAPGSSSSRMKEQIGNTEISLENIVEGGRRKRAKFESSELPLFAPPQMPAATSNPSVSPARRAEPQRASLPFVHPGQNPFTNPLPLQSPQSHSNGYGHGGHYATPSSERHGRNSIGYAGQGGNFGSMSGILPTPDPTVGSCMSEEDKDVAIQLMRLGEMSNISHGRTSASTLDDTFSGRADAASSTGATSDGESESDEEESAARRQKLGAAGAMRKIYQTTESHFIPQPSIEANADDVEAEKGSDHVDHAINGERKSEALKNKTNLPDARPKAQLPGSKPKASKVSKVPRPTVPKLKKASASAPAPAPTSNGPMSPASLPPSRKPSVSSAAAAPGANGEDDQLDLSAKPRCQRCRKSKKGCDRQRPCGRCRDAGLSADQCISEDEGNGRKGRYGRHMGVPIKKEDIVNSTQPILLPAAPIATTAATTDKNKKRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBE3</accession>
    <name>E3QBE3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_03426</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092302.1">
        <property type="nucleotide sequence ID" value="XM_008094111.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBE3"/>
    <dbReference type="GeneID" id="24408791"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03426"/>
    <dbReference type="eggNOG" id="ENOG502T491">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_447585_0_0_1"/>
    <dbReference type="OrthoDB" id="4207421at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="586"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ28282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="610" mass="66923" checksum="9052D7F53E038B52" modified="2011-01-11" version="1">MKKKSMNTLANLAPRRRDRGIKKEKMTEVKESVTPSLPANTYEPGPFESGAALTGNQDQNVDRLASELLESTIFSHPNGLRSHPSVLLCASEPMAFPSHSSGQKAKMDTSSHNLTISSPSGGNTTRSQSYAQASEMNQIPPAIPRKSSRRRRGKRTKNTDNELHLAKRSFPQSKTTLLDAGNRHGFVLSGSTTAPLGVMPKQAVGSMSDTNPDAVNPNLVNDKLAAMLAATEVLKPRGSQEITPTISIPSRNRRKKVMSKVRQALDIFQSKPKTPESSIRGKISAPIALATCDMPNPAVYYHLEEVEDASPASSAHPRANEDDDMFGNRKMKKSQTIIGGCIVRKPVPNDGSVGSSDDPFSEAYEIIRTPTPFEHRLKISIDSTDDIPPVPVLNPFAAEKDFDADLEGILSEKPLCASTPRTRTVHNAASPESPSKRYAKGDKRHLGALEETEGNTVACGPVPRKLKLAGGMRLFRDQADLSMKKHPSPSKDELNDLETRFRAYAIEQIKKAPLEEREALEIKFAGLIGPNALTPRDKNAPMKSHATKDIMYEASSVVEHKHTRESSIFSSKKSRIPRPVEPITRVPFAPRFAPQRQPTNFDAMELDELQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBK3</accession>
    <name>E3QBK3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RTA1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_03486</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092362.1">
        <property type="nucleotide sequence ID" value="XM_008094171.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBK3"/>
    <dbReference type="STRING" id="645133.E3QBK3"/>
    <dbReference type="GeneID" id="24408851"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03486"/>
    <dbReference type="eggNOG" id="ENOG502QU4U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033465_2_1_1"/>
    <dbReference type="OrthoDB" id="3358017at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF9">
        <property type="entry name" value="SPHINGOID LONG-CHAIN BASE TRANSPORTER RSB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="276"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="332"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ28342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="390" mass="42001" checksum="1C9999E0C0FE80F9" modified="2011-01-11" version="1">MTGNCGDHACPYPGGYTHYSPSVIGSAIFLVAFTLLVPLSLYQGFRFKTPLFALTLATGLLLEVLGFAGRVRLRDNGASSASFFLWLLGTISGPTLIAVAICQILPHIIALYGLGIGFTRPRVAVLLLAFALVLVSALEIAGAVSTVFGLGGVQTSSILLAALGVQVLALLLFVGLFLWFTQKIPDPKHVAIYQAPRFKNFIKMIPIIAVALIGHTIYRLVEFWNGLDSPLQRSEAASLVIGGALPLLASAMLCVYHPGAAFGRAWNLTSPRLRSASFRPRRRSAPSPLQSPTVRWDEHKGPRQPGFTTSHFPDKKMSPVGVGPVPLGQSTMASKVATSPGERSVTYPSPIASTHRLSPTFHKTKQQSANPDRHSTRSNVKPMVNSEELW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBP9</accession>
    <name>E3QBP9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_03532</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092408.1">
        <property type="nucleotide sequence ID" value="XM_008094217.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBP9"/>
    <dbReference type="STRING" id="645133.E3QBP9"/>
    <dbReference type="GeneID" id="24408897"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03532"/>
    <dbReference type="eggNOG" id="ENOG502QPW5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047439_0_0_1"/>
    <dbReference type="OrthoDB" id="5230543at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39472">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39472:SF1">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="318"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="227"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="14"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
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            <begin position="318"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="334"/>
            <end position="352"/>
        </location>
    </feature>
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        <location>
            <begin position="378"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ28388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="389" mass="43796" checksum="78606229160A3F12" modified="2011-01-11" version="1">MNVPTSSTNDFAFNSNSNSQPQQQYQQQAHFSSRQLQLQQQQQQHHQQQQYSLPPPPSPPPASSATAQSLSAAQQAFAHAQYQQFVLMNGMNGGNVPNGMGGVPTPAGQQAELNYIYSMVEELSRQLAENRRVTEDIVTGLGRVRSRARTQGMSNDDLIHNAADDIHAQEQNLDTLISILSESLEKAKYSRDANATLLTQYATVLAAMLKQFHEYKAKHVTDVAAWHRSYRSQLAEARAENSRLRDQIWEMQERAGKANEALRKFRRKYDENETRWDRRVEEVAARQELRFWKRMAMPEVSDDDPCWSDDDDLIDPAEKERQKELEKRAAQEQLAGSQQMGDEYSRSQSPESSMMGGVPMQRDLGIPMGMPVPPPRPSSATSSTGSSGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCS3</accession>
    <name>E3QCS3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_03805</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092681.1">
        <property type="nucleotide sequence ID" value="XM_008094490.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCS3"/>
    <dbReference type="GeneID" id="24409170"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03805"/>
    <dbReference type="HOGENOM" id="CLU_2739861_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ28661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="71" mass="7496" checksum="DA7C31AD70A683DD" modified="2011-01-11" version="1">MRDDHPPTTTITNTTAAAAAAAEATLTSEAAPTTGNGRPGIQGCRTRTQDEVFVDAWWEPLSRFASASLHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCT2</accession>
    <name>E3QCT2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine-rich protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_03814</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008094499.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCT2"/>
    <dbReference type="STRING" id="645133.E3QCT2"/>
    <dbReference type="GeneID" id="24409179"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03814"/>
    <dbReference type="eggNOG" id="ENOG502S8T0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003878_0_0_1"/>
    <dbReference type="OrthoDB" id="4153178at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="853"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="922"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="576"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="641"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="736"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="772"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="97"/>
            <end position="112"/>
        </location>
    </feature>
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            <begin position="199"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <begin position="239"/>
            <end position="266"/>
        </location>
    </feature>
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            <begin position="349"/>
            <end position="363"/>
        </location>
    </feature>
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            <begin position="372"/>
            <end position="401"/>
        </location>
    </feature>
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            <begin position="457"/>
            <end position="468"/>
        </location>
    </feature>
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            <begin position="489"/>
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        </location>
    </feature>
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            <begin position="499"/>
            <end position="513"/>
        </location>
    </feature>
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            <begin position="579"/>
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        </location>
    </feature>
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            <begin position="589"/>
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        </location>
    </feature>
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        </location>
    </feature>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="737"/>
            <end position="759"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ28670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="950" mass="102778" checksum="811C7E6509C5CFB2" modified="2011-01-11" version="1">MSGSGSGSPSRSQRRPLHGRSGSQSNSLAIRIVPYSPPRPSDKSRDSTASASSSRTPTSTTVLLSPNPSGHDRTSSSWADDRSASRTSDRYSHRRSYSSSNRTSVFSSASSTFPLVAAKESGVSGSKLRSDSLPGEQSSPTTPVPTTPPHQTDITTINARSRSSQRSDDDESVTPSAKRPLSRRHNLIALNADGKTFSLLPQGQRAGTQENHGSSSKAPTLSLSTTTSHGRVSDAFSENRPSSTVTSIPDRSFSSTLTPASSTTQLAGDHITTAADSSSSPWNYRMVGGLRKVPNTPDLKQEQKPTLLYPEPEPVASSPSSLFGPRLAPLPEAPTINPPLSSDTHDLQTKTSFQSSAAASTSSEKTNYKLYASNSPPATDTESVIHAPSTTSETTNYQLYGSSSPPSPERDESSQPPLSSHSNYVVLGRSSPPEPSSAERSPPKTADSEQNYVLHGASSPAPSSLASSRRSRVRPEYSQESLLVAPLKPNKKKKKRHNERFGYYKSKSRDSLRRAASAKSISGNLTLEAAQSFLASPAAFYRSRGLTGQPERQPETTSVSAPAVGVVPVASHMNAHPHQWSSQLSTVISESEGGSEPPSRSVSPWSASGRRGSIPLSSHSRQMLSISSSLAANEELSLSHSRSFTDSLERPRATHSRGNTLRMVSDQDEHGDGLTELHQLHQRPSRTRLSSFLSSSSSDRNLHSSGSSRANSLNSTSIPTWAKFYYGSGERRFLANSGDSMMSDPNDSRPPSSFQSHSPSVEHLPMNIYSQRRRPREVDPANPRPLSDVGSLEIGQAPLQNHQVRTGLRKKTSSIWSPHLRRDQRAGRYSIWEPPSMAWSAESSILGKRNMQVTLFAIGFILPFAWMIAAFLPLPPDPHAEMAEHDDRSSLRDDGRNLPRRVLAIDETLFQSARWWRALNRYMSVVGLLVVGAIAALVVVGVKQGWGQMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDE1</accession>
    <name>E3QDE1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome c oxidase assembly factor 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_04057</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Required for assembly of cytochrome c oxidase (complex IV).</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 9">Component of 250-400 kDa complexes called cytochrome oxidase assembly intermediates or COA complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the COA3 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092933.1">
        <property type="nucleotide sequence ID" value="XM_008094742.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDE1"/>
    <dbReference type="STRING" id="645133.E3QDE1"/>
    <dbReference type="GeneID" id="24409422"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04057"/>
    <dbReference type="eggNOG" id="ENOG502SEY5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_153999_2_1_1"/>
    <dbReference type="OrthoDB" id="10018333at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041752">
        <property type="entry name" value="Coa3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018628">
        <property type="entry name" value="Coa3_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15642:SF3">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 3 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15642">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09813">
        <property type="entry name" value="Coa3_cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c oxidase assembly factor 3 mitochondrial coiled-coil" evidence="10">
        <location>
            <begin position="20"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF09813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ28913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="74" mass="8331" checksum="9A49914F1C2AA279" modified="2011-01-11" version="1">MAIPQKSSYYDRNLRQGPALIRARKPYLAKNLAVGAGLWCFVGAVYWYTIKAVGQDEFEDVKVPDAPRQQAKSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QDE9</accession>
    <name>E3QDE9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04065</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092941.1">
        <property type="nucleotide sequence ID" value="XM_008094750.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QDE9"/>
    <dbReference type="STRING" id="645133.E3QDE9"/>
    <dbReference type="GeneID" id="24409430"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04065"/>
    <dbReference type="eggNOG" id="ENOG502SEWC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1777315_0_0_1"/>
    <dbReference type="OrthoDB" id="4843387at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ28921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="147" mass="16607" checksum="1E8F395544285EF8" modified="2011-01-11" version="1">MPRRAALEPKPRKPQYSPEKRARIAVLSELGMSLKEISLKEEVPVSSIKGIVTRYRLQQAGRDRPRPGRPRILSDRDVKNLLRVLKEKPAVSYAELKHEAGVTCATKTLVRYLQMEGIKPNKPPPGDSEEEASRLRVLADDAENEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3QE88</accession>
    <name>E3QE88_COLGM</name>
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        <submittedName>
            <fullName evidence="4">Fasciclin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_04320</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093196.1">
        <property type="nucleotide sequence ID" value="XM_008095005.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QE88"/>
    <dbReference type="STRING" id="645133.E3QE88"/>
    <dbReference type="GeneID" id="24409685"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04320"/>
    <dbReference type="eggNOG" id="ENOG502SQ98">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031281_0_0_1"/>
    <dbReference type="OrthoDB" id="286301at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050904">
        <property type="entry name" value="Adhesion/Biosynth-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900:SF77">
        <property type="entry name" value="FI19380P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900">
        <property type="entry name" value="PERIOSTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180449" evidence="2">
        <location>
            <begin position="22"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="3">
        <location>
            <begin position="32"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="3">
        <location>
            <begin position="218"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="345"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="349"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ29176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="404" mass="42807" checksum="4AD29F4E23AC4B41" modified="2011-01-11" version="1">MYSLLLKLALAAVGIAPLALAGSDSISPRQLQQSLSNALSKHADFSAFNQILSNYPGIVDNVTAEADNKITLLVPTNKAIANFLKQSNASDVSQIPVDRVLTIFKYHTLEAPMTAINFSSSRGITVPTKLQDSLYNLRSPGPALISRYGAGAQGQVLYISRDTINPARLRVRQGSSSSNDKVANLRAGLGQTAELTTIDGEWDGGYLQSIDTILEPPRPCSTTIRKLSDSLTSLMGALEKTMLWRTLDAKPNVTCLGPSTEAFDQAGNPEKSLGEAELKGALLFHTLPQVAYSNFLEDGQEFTSLANITVRVTVKDDEIWFNDAKVISPNVLTNNGLIHVLDRVMTPNATGPSPSDSPSSTASPTGSSTTNPSSTNAAPISGNPVTGSIHAAAFIALMAGVLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEC7</accession>
    <name>E3QEC7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04377</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093253.1">
        <property type="nucleotide sequence ID" value="XM_008095062.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEC7"/>
    <dbReference type="GeneID" id="24409742"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04377"/>
    <dbReference type="eggNOG" id="ENOG502T4JA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2223083_0_0_1"/>
    <dbReference type="OrthoDB" id="4823476at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="106" mass="12102" checksum="56BC2739606C6B60" modified="2011-01-11" version="1">MCFYRGTVYKCNHSEIGKKVSDCKDQQDFLAGTTKDKNACAERQIHSMNRVRVDANCRKCQRLDALKTRTRKTFLSLRENLEKRKAAAGKNDMEAPKAEDADKADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEN0</accession>
    <name>E3QEN0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">G-protein coupled receptors family 2 profile 2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_04480</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093356.1">
        <property type="nucleotide sequence ID" value="XM_008095165.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEN0"/>
    <dbReference type="STRING" id="645133.E3QEN0"/>
    <dbReference type="GeneID" id="24409845"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04480"/>
    <dbReference type="eggNOG" id="ENOG502RY0W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026939_0_1_1"/>
    <dbReference type="OrthoDB" id="26203at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000832">
        <property type="entry name" value="GPCR_2_secretin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053247">
        <property type="entry name" value="GPCR_GPR1/git3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42058:SF1">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 2 PROFILE 2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42058">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00002">
        <property type="entry name" value="7tm_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="254"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="7">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="352"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ29336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="372" mass="40762" checksum="7668D6D820254D77" modified="2011-01-11" version="1">MAVLIMNLGFIVPLADQPEQCYNEITPHSMKSSKVCGASGALLLLGGWAGVMWVFLRSLSLHLQICWQVVVGRTFMIFAQATGWGIPLIGIVVALVFSGVSFRFGATCHINHKNSLADFWIPLLVFAGLTVIIQFATFGYCIKVYLASLADNSATTEGSSLPTYAGSVNTMSPRQAYRRVQRVIQLQWRGIAIVLIIVTDVIFFSLVFVFQDNTVQAVHNDQSIAQDWVLCLIGAKGDRTQCYDKAKSLVVNEATITAVLVLLSMNGIWLLFLLGRWAMVLGWIDLFSSCGRSKKEFVSVDARYDVKKDTRAQITDSESQQRTKNTRLLWANGSLPAADAVFLKPSTAANTASLGRSSDLRPARITTPRGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>E3QF84</accession>
    <name>E3QF84_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CENP-T/Histone H4 histone fold domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_04666</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093542.1">
        <property type="nucleotide sequence ID" value="XM_008095351.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QF84"/>
    <dbReference type="STRING" id="645133.E3QF84"/>
    <dbReference type="GeneID" id="24410031"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04666"/>
    <dbReference type="eggNOG" id="ENOG502S8G5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024001_1_0_1"/>
    <dbReference type="OrthoDB" id="10071681at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071821">
        <property type="term" value="C:FANCM-MHF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22920">
        <property type="entry name" value="HFD_CENP-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035425">
        <property type="entry name" value="CENP-T/H4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22980:SF5">
        <property type="entry name" value="CENP-T_HISTONE H4 HISTONE FOLD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22980">
        <property type="entry name" value="CORTISTATIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15511">
        <property type="entry name" value="CENP-T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CENP-T/Histone H4 histone fold" evidence="6">
        <location>
            <begin position="407"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="21"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="241"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="370"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="503"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="56"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="112"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="139"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="173"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF15511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ29522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="536" mass="59035" checksum="B4444BBCC1F88557" modified="2011-01-11" version="1">MSSPPLRTPLAARLAAAVGADDDDPLFSPALDATTTPFRSAPNLDPPSSRASLRTPSNNPLRSSLRSSAYRGLSASGRRSVTAATTPHARAAYRTIDARRAAALTPGKNKRRESFRPRRESIHDILRGLSRVVKHDTQPISSSSSPSDLGSRAPSTSLPIRTAGGDRRSLAYGDDDDDDDELPIDRPRLSLPLDVDDDDDDLVAPELSQIDENATIEFPRRAYTDQQSRMSMGSVRLSEYRNYDDLDDDDSDGGEGFFPGFEVGALDEEGGRDQEETFDRVEDEALRRQTLASARESDFGFEVPVDADNQTTFMMAVEGQSSPARPLPEFTDEQPSLNIAPAYDEPNPPVDEDAGFGNSYYDLRSSTPIEPAEATGLDGDETKASAYAGPQHRSRKTKAGVKLSKYNMEYPSLPPAVVKRLANTFARSSGISKTKIGPEALAEIQRASDWFFEQLGDDLAAYARHAKRKTIDESDMLTLMRRQRQTSQTATPFSLAHRHLPRELLQELRMPKPPAPTEPRKKRRRVTNGEGEEEVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFH2</accession>
    <name>E3QFH2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aflatoxin regulatory protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04754</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093630.1">
        <property type="nucleotide sequence ID" value="XM_008095439.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFH2"/>
    <dbReference type="GeneID" id="24410119"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04754"/>
    <dbReference type="eggNOG" id="ENOG502RBQZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_850041_0_0_1"/>
    <dbReference type="OrthoDB" id="5423360at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101447">
        <property type="entry name" value="Formin homology 2 domain (FH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="378" mass="40556" checksum="0B5D0CB01CF9D371" modified="2011-01-11" version="1">MFANAMEQPQSASDKAQHRACDPCSRPRRRPSARPREENAVGQDALSTPTGLIDVGGFPEMMDQFFDGFNTPLPSFTMDFGPVQNSGSGSGSTQGQSAMPPPPPPPPPPPPLSTGREAEASVMPESQDRRGPCMRLHCSVVHGETNADRVTTTPAQDAGGAAPTPGLLLSKKCSCVELVSRHFSLVENPLDTFQALEVIKQSMQSAREILECGVCFESITSPRTSRNVYLLGSLLSSIGSSFGDFFYHQKRRAAESSASGEPIRLVVGQQPPEGHGTVELAVDGQSYVAFLKASLKLELDRLFGLADELATRQSQLHTEGHENCETGTSCSNTESLPAAKHPAELCPKEVDMTKACACFRTVDQVRAVIEEAQKIISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFJ4</accession>
    <name>E3QFJ4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Polysaccharide deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_04776</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093652.1">
        <property type="nucleotide sequence ID" value="XM_008095461.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFJ4"/>
    <dbReference type="STRING" id="645133.E3QFJ4"/>
    <dbReference type="GeneID" id="24410141"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04776"/>
    <dbReference type="eggNOG" id="ENOG502S8H7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022194_0_0_1"/>
    <dbReference type="OrthoDB" id="2128708at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10917">
        <property type="entry name" value="CE4_NodB_like_6s_7s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.430">
        <property type="entry name" value="Galactose-binding lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471:SF6">
        <property type="entry name" value="GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0170">Cobalt</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180374" evidence="8">
        <location>
            <begin position="21"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="9">
        <location>
            <begin position="558"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ29632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="761" mass="81838" checksum="7080E62B9266C681" modified="2011-01-11" version="1">MLHLKVRSLLATAYTAVVAAAVCSSDLLVDDLSNSFSTNRNNLGSWTSDDGSMASISASGGILSFTPKSGAYFYETLPCQALQTDSYTHVQLDIKAPVSGAAFTTELSWASSCSATTTTKTAFRVTSLTGGWQTLRIPLSSFTGANLNAALSVVIGSFSSTQQWQLDKVQFVCGQTTTTSAGITSTQAPTIPASSTTPSAPPSSCSPLLVDDWASQSRLSFLAYNALLLPTGDDGTMQSVVVDNHHVTLTPKSTSSYFYSQVGCVDATRYGGISLWVKAPAGTTFRIELSSKTTCDGAATASSTQTTAQLGWTFDGTEKLYSFSWSKFSGINLTKLRSIVISAPNQPLNLGPLAFYCGSTPSGWIVPSASSPAAPTQTVEAPAATASAFIVDAFDSPSTNSLGFWHGGEDLSLSWGQNRLTIVASASDYAFTTLMSNGCRDLRSHSGSYLHIAYSGHTRFSVSLQQHNSQCNSGVAPYPETRDSLEAGRYATGNDIYIPISHFDINLQRVSSVAIRGMYSSEPVILSKIEMVPSIPSGVSIPRKLPSGTLVFSCTRPNSFAFGIDDGNPRYAARLAEMIREAGIKVTFFAVGAVLENNATGMADLYRQLRSEGHQIALHSYTHPRMEGLASTASIDWEYNEDYRVMTGIFGEKSNYFRPPYGVEGARMRQRWAAASGAAKAYLINWSVDVQDWLWAETSTPEKQVDAFKADVAKGGNLVVMHFSYNSTVNYFPEFIRQAKATGKQIMRIDQCMEDPNAPPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QG15</accession>
    <name>E3QG15_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CASTOR ACT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_04994</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093870.1">
        <property type="nucleotide sequence ID" value="XM_008095679.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QG15"/>
    <dbReference type="GeneID" id="24410359"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04994"/>
    <dbReference type="eggNOG" id="ENOG502RXBJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036623_1_0_1"/>
    <dbReference type="OrthoDB" id="58529at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046394">
        <property type="term" value="P:carboxylic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2130.10">
        <property type="entry name" value="VC0802-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027795">
        <property type="entry name" value="CASTOR_ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051719">
        <property type="entry name" value="CASTOR_mTORC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31131:SF6">
        <property type="entry name" value="CASTOR ACT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31131">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13840">
        <property type="entry name" value="ACT_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CASTOR ACT" evidence="2">
        <location>
            <begin position="103"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ29850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="391" mass="42189" checksum="3190C07DF2B642EB" modified="2011-01-11" version="1">MNAQVSFLDGNYTLIHIPLDLYSSLLQPILRILLPQTQTLKASKGEPEHELEGLNTEGQHGFLNISVTPMECSIVCHSSWAKNVFEPAIKDLPKDLAKSVSISKDTYLVLSVISAGMDAAGRVMELTSPLALAGIPIFFITTYYSDFILVPSKDRQTVVKALLAHGFELADNDSNFVSPAASIHSRGSSQNSGPPLTPPPSTIAELQVRTFDLLKKRSVSPYVEADLLLVQCSGRETSQLGGELSHTQRPSLSRQVTGNSHRQTWLDNIDTKLYTAMISALAARPRFISITLAQDDPPSLLVDKSLLGLFGESLVGDTKTNLTPIFLDLESLPLEATGIVCGVAGTLVQDMRTGDSAGLSYLSTARAGAVILSCEQSIRALEILTPKLFKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QG27</accession>
    <name>E3QG27_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Aromatic amino acid aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_05006</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093882.1">
        <property type="nucleotide sequence ID" value="XM_008095691.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QG27"/>
    <dbReference type="STRING" id="645133.E3QG27"/>
    <dbReference type="GeneID" id="24410371"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05006"/>
    <dbReference type="eggNOG" id="KOG0634">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_0_5_1"/>
    <dbReference type="OrthoDB" id="691673at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901605">
        <property type="term" value="P:alpha-amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050859">
        <property type="entry name" value="Class-I_PLP-dep_aminotransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42790">
        <property type="entry name" value="AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42790:SF1">
        <property type="entry name" value="AROMATIC AMINO ACID AMINOTRANSFERASE, HYPOTHETICAL (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="7">
        <location>
            <begin position="198"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="68"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="89"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ29862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="612" mass="68113" checksum="2392F57FB78470B6" modified="2011-01-11" version="1">MSAAEMDHSAKRPPLDMEHHFSSVTMRRIPSKMKEYYKYFQIPGIGNLAGGLPHSSLFPFDTLEAQAAKPERWEPSPIPGDGTAGAGAAKKDKEKDVKAARHVTVPGTDAERNPLQRIDLATALQYGTAEGYPPLRSFVRQFAREQLHPDVPYLGGPEVILSCGSTDGFAKTLELLTDTWDPARDAAADRPGMLCEVFVYSQVLTQALPRGVQVVPVEMDEGGMSVGALEDVLAAWDERNGKRPSFIYTVTMGHNPTGGVLSVERRKEIYAVASKYDIIIVEDDPYYYLQYPSAAVEEARSRGVEVPPPSAPYKPAKSSGYPFIDSLTPSFLSVDTDGRVIRLDTFSKTIAPGCRLGWITAQPAIIERLLRITEVTTQQPSGFVQSTVAELVMGEQPAAARSAFAALTARQKQTFEGWQMDGWVRWLEGLRGVYERRMNRMCTILDEGAFQLKQSTPRNAKDADWGVVSKTRIYEFDWPRGGMFVWLRLRLETHPLWMATGGKTVPLLDGERLSTALMFLATKKPYRVLVSPGLIFAATPAIRAERGWAYWRLCFAAETEEKVDLCSQKLVEAIQRFWRIKKVEEVEELLGDFPPPDKEDEGFGNLGTFMGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3QG47</accession>
    <name>E3QG47_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Queuine tRNA-ribosyltransferase accessory subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Queuine tRNA-ribosyltransferase domain-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_05026</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterodimer of a catalytic subunit and an accessory subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093902.1">
        <property type="nucleotide sequence ID" value="XM_008095711.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QG47"/>
    <dbReference type="STRING" id="645133.E3QG47"/>
    <dbReference type="GeneID" id="24410391"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05026"/>
    <dbReference type="eggNOG" id="KOG3909">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037350_1_0_1"/>
    <dbReference type="OrthoDB" id="27601at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008479">
        <property type="term" value="F:tRNA-guanosine(34) queuine transglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.105">
        <property type="entry name" value="Queuine tRNA-ribosyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03043">
        <property type="entry name" value="QTRT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028592">
        <property type="entry name" value="QTRTD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050852">
        <property type="entry name" value="Queuine_tRNA-ribosyltrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036511">
        <property type="entry name" value="TGT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002616">
        <property type="entry name" value="tRNA_ribo_trans-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46064">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46064:SF1">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01702">
        <property type="entry name" value="TGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51713">
        <property type="entry name" value="tRNA-guanine transglycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA-guanine(15) transglycosylase-like" evidence="7">
        <location>
            <begin position="30"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="412"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="338"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="340"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="343"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="369"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ29882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="492" mass="53928" checksum="D7C376DB52730078" modified="2011-01-11" version="1">MSNAETFNVERNSEGMIFEILKKAANGSSAARLGRLSLPKRNPIETPNYIAVASRGVVPHVTPDNLEKYTSISAVYMALEDFIEKKNPSVLSIPSPDKKPLHTFACLPDGVATVLAPRRCPAIKTPVGNGAKFMAIFTSTGFRNLTTDEYSAAVETLKPDIAIGPADLFHTSTMPVPKKLARMAERTEEWTNAFLTPKRREAFEESGVSVFAPVLAVPHPIQWEHLRHLAEDVIDSISGLAIYDVDLLPDMEDSYEPLVSLPRLSLHIPSTPQAILRQISLGVDVCTIPFMNTISDAGVALSFTFPPPSTQSNAILPLGDDMWSPENETSLKPLVEGCQCYACTTHHRAFLHHLLNAKEMLGWTLLQIHNHHTMKEFFTGIRTTLAEEPFAEKFEEQAERFAAVYEAELPQGTGTRPRARGYHFKPDPNPSRINPPAWERFSAGGEAVANGVAGAAVAPEGTETPLVPDVGSLKLEEKGFAEVAHDKQKPEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QG88</accession>
    <name>E3QG88_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Trafficking protein particle complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_04828</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Plays a key role in the late stages of endoplasmic reticulum to Golgi traffic.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the multisubunit TRAPP (transport protein particle) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Golgi apparatus</location>
            <location evidence="7">cis-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the TRAPP small subunits family. BET3 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093704.1">
        <property type="nucleotide sequence ID" value="XM_008095513.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QG88"/>
    <dbReference type="STRING" id="645133.E3QG88"/>
    <dbReference type="GeneID" id="24410193"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04828"/>
    <dbReference type="eggNOG" id="KOG3315">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073154_2_1_1"/>
    <dbReference type="OrthoDB" id="10254842at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990070">
        <property type="term" value="C:TRAPPI protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990071">
        <property type="term" value="C:TRAPPII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990072">
        <property type="term" value="C:TRAPPIII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14943">
        <property type="entry name" value="TRAPPC5_Trs31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1380.20:FF:000007">
        <property type="entry name" value="Trafficking protein particle complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.20">
        <property type="entry name" value="Trafficking protein particle complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024096">
        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016696">
        <property type="entry name" value="TRAPP-I_su5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007194">
        <property type="entry name" value="TRAPP_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20902">
        <property type="entry name" value="41-2 PROTEIN ANTIGEN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20902:SF0">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04051">
        <property type="entry name" value="TRAPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017479">
        <property type="entry name" value="TRAPP_I_complex_Trs31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111126">
        <property type="entry name" value="Ligand-binding domain in the NO signalling and Golgi transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 7" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="6 7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR017479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ29684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="218" mass="24579" checksum="41DC904D9FF7E3D9" modified="2011-01-11" version="1">MANLPTTKTIPGKETPGLRYPSNGKTIYHRPLNRTKTAELSQSSFAYLFSEMVSYAQRNVKDITELEQRLNVQGHSIGIKLLDLLLFREPPRTQVRPLTIIALLHFIKQSCWQHLFGRQADRLEKSADPAKPDEYMIIDNEPLVNAYISVPREMSQLNCAAYVAGIVEGLCDGAGFPARVSAHNIAAKDEHEMWPGKTVFLVKFRPEVLEREGFLGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGC6</accession>
    <name>E3QGC6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phytanoyl-CoA dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05058</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ29914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093934.1">
        <property type="nucleotide sequence ID" value="XM_008095743.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGC6"/>
    <dbReference type="GeneID" id="24410423"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05058"/>
    <dbReference type="eggNOG" id="ENOG502QXCM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_880016_0_0_1"/>
    <dbReference type="OrthoDB" id="407832at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051961">
        <property type="entry name" value="Fungal_Metabolite_Diox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37563">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G03330)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37563:SF2">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G03330)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="108"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="316" mass="34676" checksum="7806D2DE4104EA7E" modified="2011-01-11" version="1">MKPTPSTTALLRLRRRLPPLPNPPSPILFVGRRAMMASLTQHRSVTTTTTPAVIRLSDGEIRDQALSPRNLELAVRHLHADGLVVVQDVVPLADVDALNSRWSRTRCTSSPSGTRGPSTTTWATCSRTLPPWRSTFTSPSSPTPSRRSSVLGPRPKLTFLSANSAMPASPSRPPQRQPVHSDADFAHPSHPFALVVNVPLVTMTPANGSTEVWLGTHAALAARRAARRPEGQPRRSRPAPLARRHAQPHRRRPRHARHDPLRALIPQPDAADPRRRREAAPQRGHRRHPRGPRGLGQPRGGAADVPGEGVREQLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGU3</accession>
    <name>E3QGU3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">KOW domain-containing protein domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_05225</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL24 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ30081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094101.1">
        <property type="nucleotide sequence ID" value="XM_008095910.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGU3"/>
    <dbReference type="STRING" id="645133.E3QGU3"/>
    <dbReference type="GeneID" id="24410590"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05225"/>
    <dbReference type="eggNOG" id="ENOG502QUDZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041333_0_0_1"/>
    <dbReference type="OrthoDB" id="359154at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06089">
        <property type="entry name" value="KOW_RPL26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003256">
        <property type="entry name" value="Ribosomal_uL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041988">
        <property type="entry name" value="Ribosomal_uL24_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12903">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22682">
        <property type="entry name" value="Ribosomal_uL24m-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ30081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="376" mass="42488" checksum="9CAB7FD2E03F5E73" modified="2011-01-11" version="1">MQKLMKRTAQAEKQVARRLKKRSRVEVGTEKAQRFRDQRNQLTELNKDIKTARLVRQEKWALGPLAPRRDVFDSYGAIQTNRQSRSTPLKPEEVEARCSWAGGRQYLNIAVNDRVVLLEGPDKGKIDRIASINLEHGTVTLKDIAKITIAVPETFQKGLDAPTTQNSSMHIPISAIRLVHPIVDPATGVARDVIVRQLARGPVKWSRHTGWRAWTRYIPGANIAIPWPERETPIREDQPGDTRRTEVEEVTFVPTLLSSPMPESVIDELRNKYSRFRTRHEEDYILRKEAEEAGKKALKKVSADALASMRTPLQEFNRQQREARRARGEPELTADMLQRIGEVIARNKAVVGGASVPIPELSNAAEAAKESHPPPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGV3</accession>
    <name>E3QGV3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Amidophosphoribosyltransferase</fullName>
            <shortName evidence="8">ATase</shortName>
            <ecNumber evidence="3 8">2.4.2.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Glutamine phosphoribosylpyrophosphate amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_05235</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>5-phospho-beta-D-ribosylamine + L-glutamate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + L-glutamine + H2O</text>
            <dbReference type="Rhea" id="RHEA:14905"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58681"/>
            <dbReference type="EC" id="2.4.2.14"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.14" evidence="3 8"/>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ30091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094111.1">
        <property type="nucleotide sequence ID" value="XM_008095920.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGV3"/>
    <dbReference type="STRING" id="645133.E3QGV3"/>
    <dbReference type="MEROPS" id="C44.001"/>
    <dbReference type="GeneID" id="24410600"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05235"/>
    <dbReference type="eggNOG" id="KOG0572">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022389_2_1_1"/>
    <dbReference type="OrthoDB" id="191723at2759"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00124"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004044">
        <property type="term" value="F:amidophosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046083">
        <property type="term" value="P:adenine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009113">
        <property type="term" value="P:purine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01931">
        <property type="entry name" value="PurF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005854">
        <property type="entry name" value="PurF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01134">
        <property type="entry name" value="purF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11907">
        <property type="entry name" value="AMIDOPHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13522">
        <property type="entry name" value="GATase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000485">
        <property type="entry name" value="Amd_phspho_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4 8 13" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="12">
        <location>
            <begin position="2"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="501"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="375"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="376"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR000485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000485-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000485-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ30091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="547" mass="59447" checksum="E38AA5C386C29737" modified="2011-01-11" version="1">MCGIIGICLGDWDREDDSCDAAQELHEAIGQDACGIATSSKHGRIYSCKDAGMASKVFNDGRRVIDLPGWMGIGHLRYPTWGSSGRAEAQPFYVNSPYGVCLSHNGNLINAEELREFLDHEAHRHVNTGSDSELMLSVFANELNETGKARVNENDLFSALERTYKRCRGAWASVIMLAGYGVCGFRDPNGIRPLVWGSRPSHTLEGAMDYMLASESVALKQLGFSNITDVLPGQAVLFKRGSPPVFKQIQEMESYSPDIFEYVYFARPDTTIDGISVHESRNLQGVKLADNIIATLGEEAVKDIDVVIPIPETSNTAAAALAERLKKPYSMGFVKNRYVFRTFIMPTQSSRKQGVRRKLSTIDTEFKGKTVLLVDDSIVRGTTSREIVNMAREAGAKKVIFSSCSPAVLNPHVYGIDLATPTELIAHGRSNSEIAQHIGADEVIYQTLEDLAASCAELSPRDPKTQTFEVGVFTGCYVTSIPEGYFERLYEARNGSKKRKAVVASSGPTAQGSADSGPAAKTVKTNGLVARSRAEILSPPGTGADIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGV6</accession>
    <name>E3QGV6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_05238</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ30094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094114.1">
        <property type="nucleotide sequence ID" value="XM_008095923.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGV6"/>
    <dbReference type="STRING" id="645133.E3QGV6"/>
    <dbReference type="GeneID" id="24410603"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05238"/>
    <dbReference type="eggNOG" id="ENOG502RJG3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041163_0_0_1"/>
    <dbReference type="OrthoDB" id="4448936at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="334"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="236"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="76"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="105"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ30094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="357" mass="39885" checksum="6490E4114BDD0ED8" modified="2011-01-11" version="1">MSDARSDSGLGLRFLDLNDHEDDDSPCKGLRRTRSHSNKPISVPQCASSPRISTPRLPSSMSCRGFSPLSPPPRQHFSTPGQQFSTPVAKSPLARSWTEDDLTASAHSNDNTNENTRDTLGLIQRLNDLTHKLLAGEDVPDSNVSAMHGKLDEIESVLAGEPPQATPQGKPKAWPMDAQNVEHESLWTSPSPSWFRSGLSEISPSFRSSFRRDTPSPEPTVEKKPAVDSFRIASEAAKLNSELETLVTNLKARQEESEHIHQLLVTRAERAAQRIIFLQGRVRDLEEELQENDSELTYLRLGLKAIEVQCPNNADPDLAQSIQNWKTDWSDLKRKRSKHKSFDRSAYNTPVGTPLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3QGW7</accession>
    <name>E3QGW7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_05249</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697347">
        <property type="protein sequence ID" value="EFQ30105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094125.1">
        <property type="nucleotide sequence ID" value="XM_008095934.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QGW7"/>
    <dbReference type="GeneID" id="24410614"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05249"/>
    <dbReference type="eggNOG" id="ENOG502TCDA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_789915_0_0_1"/>
    <dbReference type="OrthoDB" id="4808929at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ30105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="300" mass="33650" checksum="166455038E14B49C" modified="2011-01-11" version="1">MNGKDAVEHDDPDAIKTGFEAPSVFCKLIEIKEGAPFSIDITLSRGIRHILTSDDSALMAVVHLGSQEVIRHLVTKKTLGSGKALRHRFLLRGVYEKDDKLRTALKRFRFATSDMNDNIPEGIIKVDVYIVKLLSQPEIGHLVDITSSGPPPQAIMSVSRRTPNRDVFKVLTMNSFEPNKTKKSQAADTYDINKLNRGPPLASIIFKYQTKATKLFDDLTLSDPEEEKTEMNRLCLPLQPKGFLVEKGEKSDHGKTEKYEAVSHQSGRDTKSTVFRKRKAVSAFDEMSPPRPRKMIALSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QH40</accession>
    <name>E3QH40_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_05346</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697348">
        <property type="protein sequence ID" value="EFQ30202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094222.1">
        <property type="nucleotide sequence ID" value="XM_008096031.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QH40"/>
    <dbReference type="STRING" id="645133.E3QH40"/>
    <dbReference type="GeneID" id="24410711"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05346"/>
    <dbReference type="eggNOG" id="ENOG502SPN4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_138046_0_0_1"/>
    <dbReference type="OrthoDB" id="3904217at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ30202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="180" mass="19424" checksum="B7E498A6188ADBDC" modified="2011-01-11" version="1">MHSVFPLNASYSPASSNTNTGELIPEWHSIYPSGGSVYAPSGHISFVITANDTTQADVRPKTVTLPAKPTDSDHDWALVAQHSLGVFGNYRFSKVTCDGGDDKYGDKGYKSKGGNRKKGPSGVLTVDVTSATLPSYVGLQLVNTFEFTNDCSKHVLKADFGGGLVQTVWFYRLPQQDVFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHC9</accession>
    <name>E3QHC9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_05435</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697348">
        <property type="protein sequence ID" value="EFQ30291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094311.1">
        <property type="nucleotide sequence ID" value="XM_008096120.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHC9"/>
    <dbReference type="STRING" id="645133.E3QHC9"/>
    <dbReference type="GeneID" id="24410800"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05435"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_1_1"/>
    <dbReference type="OrthoDB" id="5325318at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050085">
        <property type="term" value="F:mannitol 2-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019594">
        <property type="term" value="P:mannitol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000090">
        <property type="entry name" value="NADP-dependent mannitol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF103">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE SDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="51"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ30291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="360" mass="38365" checksum="D35C1242B3F2FC9B" modified="2011-01-11" version="1">MAAARSAFRLTTRFAAPRLAVRSQAARPFSISSRTLKSDVVSEKEIPVSVYAPDAKGTGQSDHFSIPVREHDSRPPTESPIPGPENDDVVPLTRKTFDSMPPMMQKLSVMGKTIVVTGGARGLGNYMARACAEAGAKALVIFDANQELGDEAAAELHQKTGLPVTFFKVDVRDGAAINAAVDSVVELYGAPDVLVNSAGIADSNIKAETYDPAMFRRLIDINLTGSFLMSQAVGRAMMKAGKPGSIILVASMSGSIVNYPQEQSCYNASKAGVIQFGKSLAAEWAKYNIRVNCISPGYMDTALNRVPALDAQKKIWKSMTPQDRLGNVDDLNGLCVFLASDASGFMTGSNVIIDGGYTCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHN5</accession>
    <name>E3QHN5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_05517</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697349">
        <property type="protein sequence ID" value="EFQ30373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094393.1">
        <property type="nucleotide sequence ID" value="XM_008096202.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHN5"/>
    <dbReference type="GeneID" id="24410882"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05517"/>
    <dbReference type="HOGENOM" id="CLU_1677754_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ30373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="157" mass="16541" checksum="2CC34BAB2302FD91" modified="2011-01-11" version="1">MRASLTGAPLLCRLPTALTSHARTRDNADHVLVTRDTNVPYPGSTAGALPASICNRPGLHVGPGAGRARWSSMSRCCASVKGGATETLEAVTGYTRHRPDANIATVRGFTGHWVGALSRTYLMAGGGFKSQDCVCDTGAGQNMPDKWDETWAAGQRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHV5</accession>
    <name>E3QHV5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Polysaccharide deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_05587</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="GG697349">
        <property type="protein sequence ID" value="EFQ30443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094463.1">
        <property type="nucleotide sequence ID" value="XM_008096272.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHV5"/>
    <dbReference type="STRING" id="645133.E3QHV5"/>
    <dbReference type="GeneID" id="24410952"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05587"/>
    <dbReference type="eggNOG" id="ENOG502QX78">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021264_11_1_1"/>
    <dbReference type="OrthoDB" id="2125469at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10951">
        <property type="entry name" value="CE4_ClCDA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471:SF9">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0170">Cobalt</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180536" evidence="7">
        <location>
            <begin position="19"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="8">
        <location>
            <begin position="45"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ30443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="254" mass="27146" checksum="8D0B288B7F28EB23" modified="2011-01-11" version="1">MIIDTIVTGLLLAASVVAVPIENPFELIKRAPSAGVVIQKCSKPGVFALAYDDGPGQYHSQLVDILNNGGAKATFFMTGKLYGCIYNQRAAVKKAFDSGHQIASHTWTHPQNFGSLSSSQLTTEMKNLEQAFVNIIGKKPAYMRPPYLATGGAVLSTMKTLGYKVITDDIDSGDWNGQTPAQSQQKFQQAGAGGNGHIPLMHEVYASTVQTLTPWLINWAKQNNLKLVTVAECLDDSGGAYQSGSFTGNGANSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QI66</accession>
    <name>E3QI66_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_05825</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094701.1">
        <property type="nucleotide sequence ID" value="XM_008096510.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QI66"/>
    <dbReference type="GeneID" id="24411190"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05825"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_4_2_1"/>
    <dbReference type="OrthoDB" id="3639251at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000065">
        <property type="entry name" value="Putative MFS pantothenate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF15">
        <property type="entry name" value="TRANSPORTER SEO1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="265"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="310"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="336"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="362"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="396"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="429"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ30681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="508" mass="57150" checksum="705878B7D52C99D7" modified="2011-01-11" version="1">MASSSKESVPGDKWWQWRWFSSEDTKEERRLITKIDLLLVPYSVLGYWVKYIDQSNLNNAYVAGLKEDLRFYGNELVQLQTLFTLGSVLGQIPFLFIMTYVPIQYLIPICDVMWGIFTLLQYRVNSYAELAAYRFMVGWFEAAFFPAMHYVFGSWYRGHEIARRGGIFYTGLGAGTLTAGLIQAGASSSLEGVRGMEGWRWMYVICALITIPVGTLGFFVIPGTVDQPNKWCVNEKDVVIARERLEKHGHVVHGKMKFGHITRTLLGFRFWLVITTDVLFWNAGIHKTTGSYLLWIKSLGRYSAAKINEMGTIAPALGIAYTLIACFASDMFLGPAWAITICSALNAMGLIFLTIWTVPEGGLWFGFATMYWSNALSSVFHGWVNNLLRDSPEERSFTLVLINLLSQSSTAWTPLLTFPTVEAPRYRKGFSFCLGCAIALIVFTWIMYYYLKMDKRKVTGSADEETSSGVITSMAGDGKNGDDRIVEVKNVRQGEKGNQADGDGILML</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJ14</accession>
    <name>E3QJ14_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_05996</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094872.1">
        <property type="nucleotide sequence ID" value="XM_008096681.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJ14"/>
    <dbReference type="STRING" id="645133.E3QJ14"/>
    <dbReference type="GeneID" id="24411361"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05996"/>
    <dbReference type="eggNOG" id="KOG0504">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000134_18_0_1"/>
    <dbReference type="OrthoDB" id="4847958at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050889">
        <property type="entry name" value="Dendritic_Spine_Reg/Scaffold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24166:SF48">
        <property type="entry name" value="PROTEIN VAPYRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24166">
        <property type="entry name" value="ROLLING PEBBLES, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="28"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="61"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="94"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="127"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ30852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="220" mass="24342" checksum="2E408ED8F3F07411" modified="2011-01-11" version="1">MEATWGGYKELVWLLLDYGASTDVQDDRGRSALRFAMQKGYDSIAWLLLEKSAALNMADTKGRTALHWTAQNSNTSMAWLLLEKGAEIDAQDIEGHTALHFAVQRGNTEMIKLLLGKHANVTLKDAQGYAALHHAVERKDASIMNLIVDTLERSRLDVNAKDNEGKTALVRAVQGQWMLGVYILTDRKAAIDLPDCNGQTAASHAKLNGDTQILQLLEQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJ57</accession>
    <name>E3QJ57_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fumarate reductase</fullName>
            <ecNumber evidence="4">1.3.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_06039</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Irreversibly catalyzes the reduction of fumarate to succinate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>succinate + NAD(+) = fumarate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18281"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.3.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="4">Binds 1 FAD per monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.6" evidence="4"/>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094915.1">
        <property type="nucleotide sequence ID" value="XM_008096724.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJ57"/>
    <dbReference type="STRING" id="645133.E3QJ57"/>
    <dbReference type="GeneID" id="24411404"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06039"/>
    <dbReference type="eggNOG" id="KOG2404">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011398_4_5_1"/>
    <dbReference type="OrthoDB" id="10254877at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016156">
        <property type="term" value="F:fumarate reductase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-dep_OxRdtase_2_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050315">
        <property type="entry name" value="FAD-oxidoreductase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010960">
        <property type="entry name" value="Flavocytochrome_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01813">
        <property type="entry name" value="flavo_cyto_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43400">
        <property type="entry name" value="FUMARATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43400:SF12">
        <property type="entry name" value="FUMARATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0274">FAD</keyword>
    <keyword evidence="1 4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-dependent oxidoreductase 2 FAD-binding" evidence="6">
        <location>
            <begin position="57"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU366062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ30895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="519" mass="54253" checksum="BB1CFE227A47EFA2" modified="2011-01-11" version="1">MFIRPVRRFVITLVFGILAAILGMLYHQRITNKLSFITHSSTRLSSASMAKAPRGSVIVVGSGLAGLSAAHEALKAGASVHMLDRAPKPGGNSIKASSGINGAGTRFQKAAGVEKDVLFYDDTARSGGKRFAEAKGVVDRPRLVSLLTSNSADAVTWLADDVGVDLSVVAPLGGHSLPRTHRGAGTTPPGAAIVTALLKKLGEDPGFRLSSSAEVTSLDVADGAVRGVRYVQDGQEHDLRGAVVFAVGGFAGDANGLLAKHRPDLAGLPSTNEARPASHGILEAVGAAFVDMDSVQVHPTGFVDPKDPSARYKFLAAEVLRGEGGILLSGSGERFVNEMETREHVSGAIMQLPPKEDGAVRQWDVTLLMDPGACDAAAGHLGFYLWKGLMEKKRVKELSPATIKTVDEYAAVVASGTDSAFGRRTFGRWNLAAGEANREEEVCIGRVTPISHFTMGGAAFNDKSQVLREDGTAIDGLWAAGEITGGVHGDNRLGGSSLLECVVYGRIAGRQAAKAATAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJA7</accession>
    <name>E3QJA7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ribonuclease T2</fullName>
            <ecNumber evidence="2">4.6.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_06089</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the RNase T2 family.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.19" evidence="2"/>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ30945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094965.1">
        <property type="nucleotide sequence ID" value="XM_008096774.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJA7"/>
    <dbReference type="GeneID" id="24411454"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06089"/>
    <dbReference type="eggNOG" id="KOG1642">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037966_2_0_1"/>
    <dbReference type="OrthoDB" id="435754at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033897">
        <property type="term" value="F:ribonuclease T2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.730.10:FF:000020">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.730.10">
        <property type="entry name" value="Ribonuclease T2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001568">
        <property type="entry name" value="RNase_T2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036430">
        <property type="entry name" value="RNase_T2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018188">
        <property type="entry name" value="RNase_T2_His_AS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033130">
        <property type="entry name" value="RNase_T2_His_AS_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11240">
        <property type="entry name" value="RIBONUCLEASE T2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11240:SF17">
        <property type="entry name" value="RIBONUCLEASE T2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00445">
        <property type="entry name" value="Ribonuclease_T2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55895">
        <property type="entry name" value="Ribonuclease Rh-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00530">
        <property type="entry name" value="RNASE_T2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00531">
        <property type="entry name" value="RNASE_T2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178526" description="ribonuclease T2" evidence="5">
        <location>
            <begin position="20"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ30945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="323" mass="35742" checksum="31D68C782782EAF7" modified="2011-01-11" version="1">MCRTFVLLAAAGLLRTAAAGLYPGLSTANHTCTLVEPVLSCSSGANPDKVDTCCVETYGGLLLATQFWNTHTGLESEGQKLPQNAWGIHGLWPDFCNGSYTQYCDLSRQFDPTPSPNTTTGTPDGTPVPAWNGSSFDAFVKPFQRFDLLEYMNKFWIAQYTPNWVLWAHEFSKHATCYSTFDIECYGPKYQEHEEIVDFLETAVHYYQGTPTWKWLSNKAIKPSNTTAYSLADLQGALKEGHGAVPYIGCSGPQYNTTLAGKGSLDNGYTQLSEAWYYFYVYGKPQRGESVPVSADINGGRVSNCATTEDAIWYYERAEGSVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJI7</accession>
    <name>E3QJI7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_06169</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ31025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095045.1">
        <property type="nucleotide sequence ID" value="XM_008096854.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJI7"/>
    <dbReference type="STRING" id="645133.E3QJI7"/>
    <dbReference type="GeneID" id="24411534"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06169"/>
    <dbReference type="eggNOG" id="ENOG502T4CB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063077_0_0_1"/>
    <dbReference type="OrthoDB" id="4847496at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="162"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="253" mass="27726" checksum="3B5203324220992C" modified="2011-01-11" version="1">MSGPYSTDFSFLDGHRAPYIFEDNFNQSVFPSFYQYEQTPSASQPLYQPQNHEAHPQAQPPLAHDGLPPTKRLRSSTCRQRHTASWTRFPTASRSTTPDCEPPYHARIFSPESLPGGFSDVLSLSLSIPDPVGPEERLRRQHEIRHIFAETKSTTLPPPSPFAKRPSPSAAPDSPTDVYRIRAPPARISILPMQPKRSLGVFVPVADATAGAEREAAVSHNNNLAAARLADLKRRNNAAALRAAAARSAAVAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJN1</accession>
    <name>E3QJN1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">UBZ4-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_06213</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697352">
        <property type="protein sequence ID" value="EFQ31069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095089.1">
        <property type="nucleotide sequence ID" value="XM_008096898.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJN1"/>
    <dbReference type="GeneID" id="24411578"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06213"/>
    <dbReference type="eggNOG" id="ENOG502SA6U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085124_1_0_1"/>
    <dbReference type="OrthoDB" id="20105at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019240">
        <property type="entry name" value="DUF2196"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03833">
        <property type="entry name" value="YwbE family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40069">
        <property type="entry name" value="YWBE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40069:SF1">
        <property type="entry name" value="YWBE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09962">
        <property type="entry name" value="DUF2196"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="175" mass="17985" checksum="2B0B91658B5D424A" modified="2011-01-11" version="1">MSRVPTVATVVRGASVNIILKADQPTGRTVTGTVQDVLTRGNHPRGIKVRLIDGRVGRVQSHAGAQPISSASDQEPAGAGAGSAASINGRPPRRGQGRRQEADADLPPSQVGLEAYIRPVKQKSGARGRSGAAPGNETADAVSRPAASEVVTCPVCGDFEGDTSAVEHHVASHFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJP7</accession>
    <name>E3QJP7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_06229</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697353">
        <property type="protein sequence ID" value="EFQ31085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095105.1">
        <property type="nucleotide sequence ID" value="XM_008096914.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJP7"/>
    <dbReference type="STRING" id="645133.E3QJP7"/>
    <dbReference type="GeneID" id="24411594"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06229"/>
    <dbReference type="eggNOG" id="ENOG502SM04">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1786708_0_0_1"/>
    <dbReference type="OrthoDB" id="21502at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ31085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="145" mass="16336" checksum="17330AAA1CC936DF" modified="2011-01-11" version="1">MPAKELIQRPLSYLASRIRQAVTNQGSRGQVEAYASLVRQDPRNKAPPFFGESSMQFISFTNAQKANFYGFDFSAATKKPRSTSLLPSYVQILHGPYNFTNGVIILGKDDKGSYWLSGYGIKGFWGLIERETAEENICMRLKSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QK52</accession>
    <name>E3QK52_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Amino acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_06384</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697354">
        <property type="protein sequence ID" value="EFQ31240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095260.1">
        <property type="nucleotide sequence ID" value="XM_008097069.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QK52"/>
    <dbReference type="STRING" id="645133.E3QK52"/>
    <dbReference type="GeneID" id="24411749"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06384"/>
    <dbReference type="eggNOG" id="KOG1286">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007946_12_1_1"/>
    <dbReference type="OrthoDB" id="3900342at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000001">
        <property type="entry name" value="Amino acid permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004840">
        <property type="entry name" value="Amino_acid_permease_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF26">
        <property type="entry name" value="GENERAL AMINO ACID PERMEASE AGP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
        <property type="entry name" value="AMINO_ACID_PERMEASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="82"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="235"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="277"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="330"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="375"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="401"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="446"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="480"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="8">
        <location>
            <begin position="54"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ31240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="546" mass="60047" checksum="E6F0E40DA68E81F3" modified="2011-01-11" version="1">MSRYRAYDKDDDDVPVINGTGVHGAYGEEQNSIDADFSAFDPHSGVKRGLKTRHLSMMALAGIIGPGLLIGAGGALSNGGPAALLIGFGVIGIIAFSIMQSLGELTTLYPTGGAFTGLADRFVDKGFGVALGWNYFIIWMCVLANEYNVLSSIFVFWSDKVPLWGYFLIFWTVFLGFQLLGIEAFGEAEFWLALLKLIGLVAYFLFSIIYAAGGIHGQDALGFRYWRDPGAFTDGFRGVAKVFVFCSTFYAGVESVAVAATETKNPRVAVPLAIRQVFWRIILIYMGSAFFFGLTCPANADELVNGGSRAVKSPMTVAIQNAGWEGGVHLINAFIAVTCLSAVNSSIFIGSRTLLYMGQDGKAPKILGKTDSRGVPIPAIVFTNLCGALSMMNISTGASKAYSYIVNLSGVSTFLVWGSISFIHIRFRQAWKAQGHAESSLPFKSLWYPWNAYFGLAANVFLAIVQGWTTLAPFDAGSFVDAYILLPLFPMIWFGYKFWFKTHFWRVSEIDLLSGRRRDLDESREIETGEHNLDKLPWWRRLLKSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>E3QL03</accession>
    <name>E3QL03_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10">Multifunctional fusion protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="10">Delta-1-pyrroline-5-carboxylate dehydrogenase</fullName>
                <shortName evidence="10">P5C dehydrogenase</shortName>
            </recommendedName>
            <alternativeName>
                <fullName evidence="10">L-glutamate gamma-semialdehyde dehydrogenase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="9">L-glutamate gamma-semialdehyde dehydrogenase</fullName>
                <ecNumber evidence="9">1.2.1.88</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_06830</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 9">
            <text>L-glutamate 5-semialdehyde + NAD(+) + H2O = L-glutamate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:30235"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="EC" id="1.2.1.88"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Amino-acid degradation; L-proline degradation into L-glutamate; L-glutamate from L-proline: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.88" evidence="9"/>
    <dbReference type="EMBL" id="GG697356">
        <property type="protein sequence ID" value="EFQ31541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095561.1">
        <property type="nucleotide sequence ID" value="XM_008097370.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QL03"/>
    <dbReference type="STRING" id="645133.E3QL03"/>
    <dbReference type="GeneID" id="24412195"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06830"/>
    <dbReference type="eggNOG" id="KOG2455">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_4_1_1"/>
    <dbReference type="OrthoDB" id="5322683at2759"/>
    <dbReference type="UniPathway" id="UPA00261">
        <property type="reaction ID" value="UER00374"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003842">
        <property type="term" value="F:L-glutamate gamma-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010133">
        <property type="term" value="P:L-proline catabolic process to L-glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000006">
        <property type="entry name" value="1-pyrroline-5-carboxylate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000005">
        <property type="entry name" value="1-pyrroline-5-carboxylate dehydrogenase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005931">
        <property type="entry name" value="P5CDH/ALDH4A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050485">
        <property type="entry name" value="Proline_metab_enzyme"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01236">
        <property type="entry name" value="D1pyr5carbox1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42862">
        <property type="entry name" value="DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE 1, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42862:SF1">
        <property type="entry name" value="DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE 2, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0520">NAD</keyword>
    <keyword evidence="3 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 9" id="KW-0642">Proline metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="12">
        <location>
            <begin position="79"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ31541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="569" mass="62749" checksum="BF633828583699E7" modified="2011-01-11" version="1">MRPLGNEMRWATASIILSQRRTKSTAPFRLPDPRNEPSPSYKKNSVERKKLEDALSKLRGQLPVSSTLFYNGRAQAAAESLNTVLPSEHATTFSNFPLASKEQVTSAIESALEAKKSWENTPFVDRAAVFLKAAELVVTKHRYELIAATMLGQGKNMWQGEIDAAAELADFFRLNCNFAAEILEKQPTRGSDGMWSRVEWRPLEGFVYAISPFNFTAIGGNLISGPALMGNVVIWKPSPNNIYASQLLYKILLEAGLPPNVIQFVPGDAEEVTQVVLNHRDFAGLNFVGSSDVFRSLYSKIGEGIGKKTYREFPRVVGETSGKNFHLVHQTADIEHAVNHTIRGAFEYQGQKCSATSRVYLPESRAKEFISSLTSKVNEITIGSPDGKLDAFMGPVIHERSFNKIKNIIDESNRDSSLELLVGGTCDGSDGYYVNPTVYLADSPDHRLFNKEIFGPVLAISIYPDSEWSSTLKKVDQSGGGFALTGAVFANDRIAIREAEDALRYSAGNFYINCKTTAALIGQQSFGGARASGTNDKAGSADAMRRFVSPRLIKEEFFLQTEFLYPSNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLI3</accession>
    <name>E3QLI3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_06696</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PheA/TfdB FAD monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697357">
        <property type="protein sequence ID" value="EFQ31721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095741.1">
        <property type="nucleotide sequence ID" value="XM_008097550.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLI3"/>
    <dbReference type="STRING" id="645133.E3QLI3"/>
    <dbReference type="GeneID" id="24412061"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06696"/>
    <dbReference type="eggNOG" id="KOG3855">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_9_2_1"/>
    <dbReference type="OrthoDB" id="1716816at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02979">
        <property type="entry name" value="PHOX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012941">
        <property type="entry name" value="Phe_hydrox_C_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038220">
        <property type="entry name" value="PHOX_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF20">
        <property type="entry name" value="2-MONOOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G13660)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07976">
        <property type="entry name" value="Phe_hydrox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="8"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="Phenol hydroxylase-like C-terminal dimerisation" evidence="6">
        <location>
            <begin position="455"/>
            <end position="677"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ31721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="679" mass="75532" checksum="1D1DD315E4EF5A8C" modified="2011-01-11" version="1">MTALPDSEVDVLIIGAGPAGLMLALWLSRLGVKTRIVDKRTSRIYSGQADGFQVRTLEILDSFGVGERVWKEANRMLEVSFWNPDKSGKIARSAHVANTIPGLSRFTESVLHQGRIEQFFLEAIRASYASAADALHVERMVIPTSLEIDESKAEDPDAHPVTVTLRHLTEEEATPTQMLSNLNDGLFRSNLADDDVGEMLDRSKGREARDEIVRAKYVVGCDGAHSWTRKTLGEGFEMKGETTDAIWGVMDIVPITDFPDIRFRTIINSTSGAVMVIPRENRIVRLYIQLKEVTAGGGRVDRSQITPDFIFKSAQQIFNPYKLEYHYCDWWTAYQIGQRTGDNFSKLNRVFLAGDAVHTHSPKAGQGMNVSMQDSYNLGWKIGLACKNILPRHALATYELERKKIAKDLIAFDGKFSKLFTGRPAKDIQNETGVTDDELQQAFHKSRMFTSGVGVDYQPTVFVAKEAEETDQDSGLRKSAAESTPSLAANCKLGQRFPSHKVISQSDARLWELHHKIPSDGRFRLVVFGGDISRGPQRDSVNALGAWLSSYLPGLPTIGLSPSSDPHGGSMKFKTDADPSIVDVLLVHTAPRDEVEVLRDVHEAYHPFDSKLGWDYDKIFVDGETMYEEPQKAYEKYGIDRVKGAVVGLRPDGYVGLVTSVDHGGQEQIQKWLDGVFHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QN62</accession>
    <name>E3QN62_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Methyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_07444</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697361">
        <property type="protein sequence ID" value="EFQ32300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096320.1">
        <property type="nucleotide sequence ID" value="XM_008098129.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QN62"/>
    <dbReference type="STRING" id="645133.E3QN62"/>
    <dbReference type="GeneID" id="24412809"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07444"/>
    <dbReference type="eggNOG" id="KOG4300">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037990_6_0_1"/>
    <dbReference type="OrthoDB" id="540004at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052356">
        <property type="entry name" value="Thiol_S-MT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45036:SF1">
        <property type="entry name" value="METHYLTRANSFERASE LIKE 7A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45036">
        <property type="entry name" value="METHYLTRANSFERASE LIKE 7B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ32300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="296" mass="32867" checksum="17D207C2AF9C99FD" modified="2011-01-11" version="1">MPTLSQICEVFWGLVGPWIFMSKSFYYLPPTIFGLIRSADFATLLSPSRLQDVWFSAFWAWWGPRIRVGNSDRIVALLEGRVTGGSAVEDPVHSPVGGVVLEIGPGSGLWVNLFSKGGKKSEASQGAVRRRVVEGVSKVYGVEPNSGVHPVLRERVLEAGLDGTYEIVPTGIESLSDPTAWNGKIEKGSVDCIVSILCLCSIPEPEKNIPELYSYLKKGGRWYLFEHVKATHSRPIQLYQRFVNLVWPRALNGCQLCRDTGKTLRSAGPWAKIDVSHPPDEPWYQIVPHIFGTFTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNH6</accession>
    <name>E3QNH6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="18">CFEM domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">GLRG_07733</name>
    </gene>
    <organism evidence="19">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
            <topology evidence="2">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="GG697362">
        <property type="protein sequence ID" value="EFQ32463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096483.1">
        <property type="nucleotide sequence ID" value="XM_008098292.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNH6"/>
    <dbReference type="STRING" id="645133.E3QNH6"/>
    <dbReference type="GeneID" id="24413098"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07733"/>
    <dbReference type="eggNOG" id="ENOG502SM6F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_6_3_1"/>
    <dbReference type="OrthoDB" id="2496787at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF160">
        <property type="entry name" value="SAT4 FAMILY MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00747">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="12" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="10 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="7 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="155"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="194"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="274"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="314"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="17">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="402"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="408"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="28"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="37"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EFQ32463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="422" mass="46826" checksum="2B6C19D9884F7AB3" modified="2011-01-11" version="1">MDTPAPLDTPPLCGLKCIQQVTMATGLCPLTNTTCLCTDVQLNKQISLCVHSNCTVREVLQVQRYTKHECGAPSRDRTALVWIVGTVFLALGLLAFVLRVVSKIFLGSQTWGLEDWAILLAVAIMIPLNGLSYPISRVALGKDVWNVQPNDITQFLYIFYWQEVLYLGALPVTKISILLFYLKIFSKKEIRLGCWVLLGLNIAYLIVFELTCVFQCRPVEGAWKGWDGEFPAKCNNINAQGWAAAIANIALDLATLLLPLRELYSLSLSLKKKLMVMMMFCVGFFVTIVSIVRLDSLATYATTSNVTQDYVEVGYWSTIEVPVGIICASMPAIYSLFSVVFPKVFGSTQRGGLSDYANLSEPTDPTSGALKLPAIRVQKEFFLKSGRRGDVSYTDHELSQLPFRDPNSRSSQKKLATTLESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNS8</accession>
    <name>E3QNS8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Metallo-beta-lactamase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_07705</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-beta-lactamase superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697362">
        <property type="protein sequence ID" value="EFQ32435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096455.1">
        <property type="nucleotide sequence ID" value="XM_008098264.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNS8"/>
    <dbReference type="STRING" id="645133.E3QNS8"/>
    <dbReference type="GeneID" id="24413070"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07705"/>
    <dbReference type="eggNOG" id="ENOG502RR4S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030571_3_5_1"/>
    <dbReference type="OrthoDB" id="10250730at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07729">
        <property type="entry name" value="AHL_lactonase_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051013">
        <property type="entry name" value="MBL_superfamily_lactonases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42978:SF2">
        <property type="entry name" value="102 KBASES UNSTABLE REGION: FROM 1 TO 119443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42978">
        <property type="entry name" value="QUORUM-QUENCHING LACTONASE YTNP-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="6">
        <location>
            <begin position="56"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ32435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="304" mass="33634" checksum="DF3E45FF4562E7D6" modified="2011-01-11" version="1">MSPVANMASDDRISLEFITTGNVWMRNPMQGQPVTNRSITMRLLRSFTGEWIGPMPLGAFLIRHPNGPILFDTGVSTHCTEPGYFPCWNPVPGFLNKLEVTKEDGIVEQLSQRGIKPTDLQFIVISHLHHDHAGGLEELAVAAPEVPIYVGSEHWDAFGKHPLYAAMQGCTPDRWPKNFEPLMLDFEEGRAVGPWGRSCALAANGTVVAVDTPGHVPGHVSLIVVGDNKDGTKTRYLLTGDATYAISVLEKEEPDGANTDPEAAFESLRRIKEYARRHDVVVLPSHDPDTPRLLRDKVVYRPKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPD6</accession>
    <name>E3QPD6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_07868</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697364">
        <property type="protein sequence ID" value="EFQ32724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096744.1">
        <property type="nucleotide sequence ID" value="XM_008098553.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPD6"/>
    <dbReference type="GeneID" id="24413233"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07868"/>
    <dbReference type="eggNOG" id="ENOG502RCZR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065853_1_0_1"/>
    <dbReference type="OrthoDB" id="2101473at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007396">
        <property type="entry name" value="TR_PAI2-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35802">
        <property type="entry name" value="PROTEASE SYNTHASE AND SPORULATION PROTEIN PAI 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35802:SF1">
        <property type="entry name" value="PROTEASE SYNTHASE AND SPORULATION PROTEIN PAI 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04299">
        <property type="entry name" value="FMN_bind_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010372">
        <property type="entry name" value="PaiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ32724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="257" mass="28594" checksum="EAB36358EEDAD75A" modified="2011-01-11" version="1">MYLRADHAENSIPALRQLIKDDPLGVLTTAIHSTSEPFIQSSHIPWVLDVQDDSSETELGILRGHMARANPQSKTIIESLSADNRTGTGNVLDQEVLVLFTAPTHHYVTPKFYTDTKPTTGKVVPTWNYAAVQAYGRAKIYYEPKSEETSAFLTRQIHELSQHGETSVMGYTGKDGRPGPWEVADAPEKYIELMKKAIIGIEITIDRLQGKFKMSQESGEGDRDGIVQGFNALGSEVGSKMSDLVKERGELKKRYKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPK4</accession>
    <name>E3QPK4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_08053</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697365">
        <property type="protein sequence ID" value="EFQ32909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096929.1">
        <property type="nucleotide sequence ID" value="XM_008098738.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QPK4"/>
    <dbReference type="STRING" id="645133.E3QPK4"/>
    <dbReference type="GeneID" id="24413418"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08053"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_44_6_1"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF282">
        <property type="entry name" value="WW DOMAIN-CONTAINING OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ32909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="290" mass="31521" checksum="F245FEA90E26841F" modified="2011-01-11" version="1">MTFHPDTLPDVEGTSFIVTGGNSGIGYYTVAYLAQHGAHVYLCAPSAEKGAAAIATIKQLHPSANIDILQMDLMDLSSVVAAARRFLTLETTLHGLVNNAGIMATPFEMTKDGHEAQWQTNYLAHWVLTDHLLPVMLRTAKTLPPGSVRIANLTSSGHLGAPTGGINFEDPSLKDGDPWLRYGQSKLANILHTKTLHTTYGPGSVRARNREGEIWVSSVHPGVVETKLASSMEATGSGMMRILSVLRMFGLTWSADKGSWNSLYCAASRDMKAEQSGSYMDVFRRFGEPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QPU2</accession>
    <name>E3QPU2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ferric reductase like transmembrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_08013</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697365">
        <property type="protein sequence ID" value="EFQ32869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008098698.1"/>
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    <dbReference type="AlphaFoldDB" id="E3QPU2"/>
    <dbReference type="STRING" id="645133.E3QPU2"/>
    <dbReference type="GeneID" id="24413378"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08013"/>
    <dbReference type="eggNOG" id="KOG0039">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010365_3_1_1"/>
    <dbReference type="OrthoDB" id="167398at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000293">
        <property type="term" value="F:ferric-chelate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015677">
        <property type="term" value="P:copper ion import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF12">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G14340)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="30"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="225"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="254"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="8">
        <location>
            <begin position="310"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ32869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="474" mass="52717" checksum="14132B5FACD5AC33" modified="2011-01-11" version="1">MEAVDFHFEDSLIDPYDEGLHGVNQSDNIAFVQILWASLGLLTSIVVSVQLVLHQTNSRRRIALAEAPKETHQDAWVRPVFPWVPGVKRRFLYAPLFSLRRARRLHWFGSLSTRSHAIFLLFYAASNIAYMFAVNFDSWTNRYTGGGEHGPAGPSNRARQPHNGLVAVELRRLHHASSLDCPGLTFYAGRTVVLEILLHGIVWAVVHVADKGWSSVGVKVVHHDFIRAGFVGWVALALILVLSLPPVRAACYEALVNIHILLATIIIGSTIAHCKLSGFDLPHTPWNIAAAVLWAVERLLRALRLVRYSLTRQGRTITDIETIEGTSNMCRITMNLPCRVDIKPGTHAYIRLGAVKFRETHPFSMAWVEHRLYPTARGFSQRKITTVVSFIVCAQQGFTRDLFNRVSASGGVLTTNATFKGPYGGHTSLDSYGHVVLIAGASGITHQIGYARRLVLGFNSQTTATRRIVLVWVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QR53</accession>
    <name>E3QR53_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_08485</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697369">
        <property type="protein sequence ID" value="EFQ33341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008099170.1"/>
    </dbReference>
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    <dbReference type="STRING" id="645133.E3QR53"/>
    <dbReference type="GeneID" id="24413850"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08485"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1525027_0_0_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ33341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="176" mass="20139" checksum="09D68B849B36FD0B" modified="2011-01-11" version="1">MRQAKDIPTRRREFDKSSFLPDGMESMGYLHGIYTTGDKFKSNRQLIQDRMTSSFLDNHVGPAVLNKGLELVELWWLRAKLARGRPFSVKKDLEYTSLGVMLDFAFGSNWKHTALGPQVQLLSRLALEDIDIKTVDDPVSLPTVPLADFPNSVYEAPEVVEKTINALMPKLQTWWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRN0</accession>
    <name>E3QRN0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Helix-loop-helix DNA-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_08797</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697371">
        <property type="protein sequence ID" value="EFQ33518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097538.1">
        <property type="nucleotide sequence ID" value="XM_008099347.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRN0"/>
    <dbReference type="SMR" id="E3QRN0"/>
    <dbReference type="STRING" id="645133.E3QRN0"/>
    <dbReference type="GeneID" id="24414162"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08797"/>
    <dbReference type="eggNOG" id="KOG2588">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041446_0_0_1"/>
    <dbReference type="OrthoDB" id="2133190at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052099">
        <property type="entry name" value="Regulatory_TF_Diverse"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47336">
        <property type="entry name" value="TRANSCRIPTION FACTOR HMS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47336:SF2">
        <property type="entry name" value="TRANSCRIPTION FACTOR HMS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="3">
        <location>
            <begin position="385"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="155"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="328"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="412"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="450"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="28"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="55"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="328"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="341"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="360"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="376"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ33518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="502" mass="54857" checksum="B76B35C96D31B2C2" modified="2011-01-11" version="1">MDSNFLRNLDYFAVPNNQATNPVERSAESSAESSATGAARNAPDTSLWDSLAGDQANSESTSNGPSTSLPSFAQASPGSTNFGLGSMPSQMQFSHGQPRNSLPNRPAVGQNSRRRDGHARKRTKVDSEAAALESVDYWIQFDDDEEQKLGGSFEIDFSRRSNPTPNYRPRPAANRLNPMSTTPGLGAGLYTNPVFKPEDFMDDTALDNALSDDDDFFESMNLGEQLGKIDSQPPQEVPPREGLYSTPLSWEKPAPGLRMNPLFGMGGLGSMGMPMLDPEQRRLLAIALNTGGRSSATGLGSSLGFGLGADLGPEFASLENFDANMATGSLNDTTKGPKQSALEKGKQKENDTVKEEAQPQRPQVSRTNTNATGTSEKSRDKLKTGDRTAHNDIERKYRTNLKDRISELRDAVPSLRSIPEEGGEDAEADGQSRGPKVSKGTVLTKATEYIHYLERRNKAIMREHQELARRLQAFEQLLSAQARQPFPMPNYSRTLFDPRGFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>E3QRQ6</accession>
    <name>E3QRQ6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Clathrin-coated vesicle protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_08823</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697371">
        <property type="protein sequence ID" value="EFQ33544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097564.1">
        <property type="nucleotide sequence ID" value="XM_008099373.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QRQ6"/>
    <dbReference type="GeneID" id="24414188"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08823"/>
    <dbReference type="eggNOG" id="KOG2137">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008724_1_0_1"/>
    <dbReference type="OrthoDB" id="79687at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14011">
        <property type="entry name" value="PK_SCY1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051177">
        <property type="entry name" value="CIK-Related_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12984:SF6">
        <property type="entry name" value="SCY1-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12984">
        <property type="entry name" value="SCY1-RELATED S/T PROTEIN KINASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="662"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="717"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="669"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="747"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="776"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="804"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="862"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="879"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="905"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="916"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="973"/>
            <end position="983"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ33544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="992" mass="106082" checksum="0097187741E7F62C" modified="2011-01-11" version="1">MFSSALKSISSTNITANYSISSTQTSSAGPWKIYDCKKKSTGKPYSVFVFDKKALDGHGSSLGRSSASAFKRATEEVIERLKKEASSLAKLRHPSVLELVEPVEETRGGGLQFVTEAVTGSLAALLQEKDDQERSGGVGGRSSRYVTEDSDGVRRRRELEIDELEIQKGLLQISKALEFLHENAGLVHGNLTPDAIIVNAKSDWKISGLAFCGPSEGSNKPTSFQPVSLSEVLNPDPRLPRFVQLDLDYTSPDFVIDNNFTNFADMFSLGLLAVALYNSPHRSPIESHGSLSTYKRTFSSSSTVPSASNGFLSSRPLPKELVQHVLPRLITRRPAQRLTAKEFQESEYFNNVLVSTIRFLDAFPAKTPNEKTQFMRGLVKVMPSFPKTVMEKKLLPALLEEMKDKDLIALILQNVFTIIDLLPSARRVFAEKVRPALKATFAPPPKKDQPPERDPTKDAGLMVVLEHMSTICSNCNGKEFTDDILPVVYAAIEAPTPAVVDAALRGLPSILPVLDFSTIKNELFPVIAAVFSKTSSLAIKVRGCQAFVVLCGGTPDGQDDGLDAFGAAKKKPSSSSSMLDKYTMQEKIIPLIRAIKTKEPAVMMAAHGVLRVVGEAADAEFVAIDILPILWHMSLGPLLNLKQFQDFMDLIKKLSKRVEDEQSKKLQELSGTNGSTSAPNEDFMAFGGVSGTTFDNGGAEDDFESLVKGKTTRTSTSDAFSSWEEMPASARVASPAPGSRSTTPAFSWSSPSPTQAAPPSAKPQPSFRTVTPDLASFQTMSPTSTQFSKPLQPVKETPAQPAQSSSTINWSTASAATSNPWASSSTPTPAFSSGSSISPPPSSAFGGISAPMSNLSLGGQRPGLSQSSSFSLPPPPSSNPTGLSGSSGFSLPPPPSHTPPVQSSMSAFSKPATNAGSMSMMGQQPMGSMSSIGSMGSMGSRPGMNMGSMGMASGGSMNTMMNGNTGMNSMAGLQQQQRPQQKSGLDKYESLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>E3QS13</accession>
    <name>E3QS13_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_08580</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697372">
        <property type="protein sequence ID" value="EFQ33651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008097671.1">
        <property type="nucleotide sequence ID" value="XM_008099480.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QS13"/>
    <dbReference type="STRING" id="645133.E3QS13"/>
    <dbReference type="GeneID" id="24413945"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_08580"/>
    <dbReference type="eggNOG" id="KOG2893">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037132_0_0_1"/>
    <dbReference type="OrthoDB" id="1306014at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20908">
        <property type="entry name" value="SUF4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000354">
        <property type="entry name" value="C2H2 finger domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003656">
        <property type="entry name" value="Znf_BED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23215:SF0">
        <property type="entry name" value="BUB3-INTERACTING AND GLEBS MOTIF-CONTAINING PROTEIN ZNF207"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23215">
        <property type="entry name" value="ZINC FINGER PROTEIN 207"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50808">
        <property type="entry name" value="ZF_BED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="BED-type" evidence="9">
        <location>
            <begin position="13"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="115"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="155"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="291"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="291"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="309"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ33651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="348" mass="37695" checksum="4AF8D3EFC9DD98E0" modified="2011-01-11" version="1">MGKKKRGHPDVEDVLARPWCYYCERDFEDLKLLISHQKAKHFKCDRCGRRLNTAGGLSVHLNQVHKETLTQVENALPNRQGLDVEIFGMEGIPQDILDQHRNRIIQNFYQAQEDRRIATGNPLPGQAKQPRKKLKVETPEELKARLAEHRARVAAGHTPGTSGSPANGAPSSASPGAFNNSPYPPPQAPYGASPDQSFPPGAAPGAPAFPQPGYPQGNYSGFSPSSLPARPTSGLQAMPGLPQRPPQYGGQFWNGSGAPPPGYPGASTVDELVSGAAQHGDEIDELIRRAESGIKAPKKPEDEAAEEAAGDKKSKKDKNGRMFYADTEVSPEERMAQLPRYAYVPPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QT53</accession>
    <name>E3QT53_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_09185</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697376">
        <property type="protein sequence ID" value="EFQ34041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098061.1">
        <property type="nucleotide sequence ID" value="XM_008099870.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QT53"/>
    <dbReference type="STRING" id="645133.E3QT53"/>
    <dbReference type="GeneID" id="24414550"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09185"/>
    <dbReference type="eggNOG" id="ENOG502RS6B">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070655_1_0_1"/>
    <dbReference type="OrthoDB" id="3596146at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ34041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="256" mass="27439" checksum="8F8B001029E39E37" modified="2011-01-11" version="1">MEMPSAAARAGARLLGDVEEANLEEILNAFRTALSPDASSSKAKHPKTYPIHGLGALVNRNFRATKSAPLAITGRHLPLIYSLVSALVSPPHNKTVLVLDTEHRFDATRLICGPDNIRHVYVHRPACFSIPEQHGVSSAGMGPDQARDLVAAAENWMLYGDHASSSREWWGTIVIGAVGAGDVTGAWKGWLRIDRDTVPGFSLGCSAKEAMADRQRRQEAVDAAPWTASSQWGGFTFTEPGASVTATSIDLTDVAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3QTK9</accession>
    <name>E3QTK9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09341</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697377">
        <property type="protein sequence ID" value="EFQ34197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098217.1">
        <property type="nucleotide sequence ID" value="XM_008100026.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QTK9"/>
    <dbReference type="STRING" id="645133.E3QTK9"/>
    <dbReference type="GeneID" id="24414706"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09341"/>
    <dbReference type="eggNOG" id="ENOG502SKGQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027514_1_0_1"/>
    <dbReference type="OrthoDB" id="3251507at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027796">
        <property type="entry name" value="OTT_1508_deam-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42037">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42037:SF1">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14441">
        <property type="entry name" value="OTT_1508_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180929" evidence="1">
        <location>
            <begin position="33"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="463" mass="52803" checksum="2B55C78078638E5F" modified="2011-01-11" version="1">MALTPRMDPYARLLFRLYEALVLLSILRPVNGSHLITQLSSYTIQDARRRFLKNLCFLCDYKKGGGSTTAIAVEEREDCHVFWVSSNEGPGGGITRHISDVLDHVQRFASHSEDRVTSEEALLVMCTAFASLRIRQLIRILRNAARKCRVSLEGAQKEHNDGIMNWLRSFEDNNSSELSMCRAAYCARNDEELRQIEQFGQESEETPDVMQTLPAFRAVKHMIGRLAAYIRAVSQLLDDGSRLRKLLMDYRIVYSVQCPASAAVPEADPHTTLSGVLKRLLPNQDIRYPQYLRFLADLDKQVHLESRLHREFEPGKLEPGVHAEVQLLHHFYSEKRQFAAKDRYIACSKPACICCELYFRHHPAKVCLLDSHRKVYPNWGILSLEGGAENPHWLEYRRTINGVVGDLKFMVLDQISELQILSCERQDTLTQITTSQGSVDGDSDSEMDTFGNFGKIETPVNRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QU54</accession>
    <name>E3QU54_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_09536</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697379">
        <property type="protein sequence ID" value="EFQ34392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098412.1">
        <property type="nucleotide sequence ID" value="XM_008100221.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QU54"/>
    <dbReference type="GeneID" id="24414901"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09536"/>
    <dbReference type="eggNOG" id="KOG1808">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_936934_0_0_1"/>
    <dbReference type="OrthoDB" id="10493182at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ34392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="297" mass="31733" checksum="ED4161AB252BB215" modified="2011-01-11" version="1">MDAGYSYPAPAGSEAEFAPGTAPDHPNSAPYLLPYLNGGQDGEEEGGGQYGEAVSHTSDDVVPVFSEDEFREILETEWGYAAFNGLLPEPAAGSSALPTAGPAPMAEMDLLGPDVPLGSSQHPGFMPAVGPPPVVYQPSAFGPAAAAPDIPGFLAAAAPGNAAGPIAPQAHATSVPPAGIVVQQPLYPPGFRIQDNLVLRHDWPQGLLQPSPRHFTYERSGNPKPAQDNAVWCNSCEYWLWEPCYERAPLSARDRARCCNRCHWRKKSARGMGLHEWMLAAQPRMMHLLKKDAGYVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUD6</accession>
    <name>E3QUD6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">ER transporter 6TM N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_09618</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697380">
        <property type="protein sequence ID" value="EFQ34474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098494.1">
        <property type="nucleotide sequence ID" value="XM_008100303.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUD6"/>
    <dbReference type="STRING" id="645133.E3QUD6"/>
    <dbReference type="GeneID" id="24414983"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09618"/>
    <dbReference type="eggNOG" id="KOG4711">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001788_0_1_1"/>
    <dbReference type="OrthoDB" id="2274698at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018823">
        <property type="entry name" value="ArAE_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018820">
        <property type="entry name" value="BRE4-related_DUF2421"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049453">
        <property type="entry name" value="Memb_transporter_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37994">
        <property type="entry name" value="ARAE_2_N DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37994:SF4">
        <property type="entry name" value="ER TRANSPORTER 6TM N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10337">
        <property type="entry name" value="ArAE_2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10334">
        <property type="entry name" value="BRE4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13515">
        <property type="entry name" value="FUSC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="625"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="654"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="688"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="725"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="770"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="domain" description="Putative ER transporter 6TM N-terminal" evidence="8">
        <location>
            <begin position="54"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="Integral membrane bound transporter" evidence="9">
        <location>
            <begin position="648"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2421" evidence="7">
        <location>
            <begin position="789"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="24"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF10334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ34474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1105" mass="122905" checksum="8EBC02141A206C97" modified="2011-01-11" version="1">MSSEEQRADPDADDRYEESPEPQPESVPARSATAASHASRKPAPKQKLTDRLGLDVPTVLMMFKGSLPPIIGIAIYQSPPVAQYFTTLGYLVAIISVLAFAILPRGKYLQNLVLNVSGILIGAAISMLALWSGVQARRNTASADELASGLPVYNSSQSAVCGIWLFFNIWISNTLRAKYPATNLPVMIYSIFMNVACTFGPLMVTTAAAESFVKRLLVAMLAAMGIATGVSLLVFPVSSRQVVSGEFKGVIGLVRKSMRLQLNYLQTLSSPDMLERHQTKGSNVFKKKKNKGPELTHEAKAAGELKATTLAIAALFGKMHGDILFAKRDIAYGKLDSKDIGEIYNRLRSVMIPLNGISTIVDIFRRASEEHGWGANAGTRGDSEVERSREKKVWNDIMEQLCEPFEILVEAMDQGLNHASIVLELVPRPKKTKTDDVENEAGTKADAKPGDVGFSELLAKRVQDFNGKRGVMLKAWLRERRHVTEQELQDLNLKRLETRMRERDQTQLYVMLYMEKLMLALGEAVQDLVMFADSKVADGTMGRKRLIIPSQKRIKKWFKGIGSTEDASPEQTPDIAEMGANIVYAGDGYNKKKDPEHLPARTAWEHFGNYLRQFSGFVGSGESMFGFRVSIATMTIGITAFLQSTQTFFNEQRLVWAMIMIAIGMTITAGQSIFGFVCRVGGTCVAVIFSYIIWYIVVGHTAGVIVILWLFIFVEQYFILKYPRFMPVWLVTIITQVLIIGYELQVQKIGEAAAAATGQPYYPTYLLAPYRLACVAAGCAVAFIWTIFPAPMTDRRWLRRDLSASLYLLANYFSVVTETIKARMEETDGDIKKPGTPAHKMEKERSRILGKLLLLLPSLDSHAQWQKWEPDIGGKFPRATYEDVIRRSTSIMRYLTLISYTITWKPRDLPSTPSSESDRQWLRALNQVLASIEPTQHTILSTLTLLSNSLLSGQSLPPFMHLPRPNELTRRLLHLRGPTPDQAIQRRGSELEHRLVTVHTRTGTEVRPSGQTPSVFESSESPELAEMMSSLGNGSILDVRNVEQQGYTEFAVLQVCSSLVCDDLEGLVRSISSLVGVVDFSFRINPSETTLTSSEDDTGDKGKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3QUI0</accession>
    <name>E3QUI0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phospho-2-dehydro-3-deoxyheptonate aldolase</fullName>
            <ecNumber evidence="8">2.5.1.54</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_09662</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>D-erythrose 4-phosphate + phosphoenolpyruvate + H2O = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14717"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="2.5.1.54"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 1/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the class-I DAHP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.54" evidence="8"/>
    <dbReference type="EMBL" id="GG697381">
        <property type="protein sequence ID" value="EFQ34518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098538.1">
        <property type="nucleotide sequence ID" value="XM_008100347.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QUI0"/>
    <dbReference type="STRING" id="645133.E3QUI0"/>
    <dbReference type="GeneID" id="24415027"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09662"/>
    <dbReference type="eggNOG" id="ENOG502QPSU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030903_0_1_1"/>
    <dbReference type="OrthoDB" id="4699125at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003849">
        <property type="term" value="F:3-deoxy-7-phosphoheptulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000005">
        <property type="entry name" value="Phospho-2-dehydro-3-deoxyheptonate aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006219">
        <property type="entry name" value="DAHP_synth_1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00034">
        <property type="entry name" value="aroFGH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009395">
        <property type="entry name" value="PRK12755.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21225">
        <property type="entry name" value="PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE DAHP SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21225:SF12">
        <property type="entry name" value="PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE, TYROSINE-INHIBITED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001361">
        <property type="entry name" value="DAHP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAHP synthetase I/KDSA" evidence="10">
        <location>
            <begin position="49"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="358"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="369"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR001361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ34518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="382" mass="41197" checksum="D92647052FB8F313" modified="2011-01-11" version="1">MPGLDLEHEPLAADDVRILGQDPLIPPALLSSEIPMTDAALQTVVKGRNEAVDIIMGRDDRLLVIIGPCSLHDPATALEYCERLKALAERLSGDLCVIMRAYLEKPRTTVGWKGLINDPDIDSTFKINKGLRISRQLFRDLTAAGMPIASEMLDTISPQFLADFISVGAIGARTTESQLHRELASGLSFPVGFKNGTDGNLGVAIDAIGAAAAKHHFMGVTKQGLAAITRTKGNEHGFVILRGGSYGPNYDKENVQKAKDTLTKKGQKQAIMIDCSHGNSNKDHRNQPKVAAVIGDQLREGETSIIGVMIESNINEGNQKVPAEGPAALKKGVSITDACIDWESTVDVLEDLAAAVRARRERNVGSSKSNEDSHRVTHLEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QVF2</accession>
    <name>E3QVF2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pentatricopeptide repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_09984</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Regulates mitochondrial small subunit maturation by controlling 15S rRNA 5'-end processing. Localizes to the 5' precursor of the 15S rRNA in a position that is subsequently occupied by mS47 in the mature yeast mtSSU. Uses structure and sequence-specific RNA recognition, binding to a single-stranded region of the precursor and specifically recognizing bases -6 to -1. The exchange of Ccm1 for mS47 is coupled to the irreversible removal of precursor rRNA that is accompanied by conformational changes of the mitoribosomal proteins uS5m and mS26. These conformational changes signal completion of 5'-end rRNA processing through protection of the mature 5'-end of the 15S rRNA and stabilization of mS47. The removal of the 5' precursor together with the dissociation of Ccm1 may be catalyzed by the 5'-3' exoribonuclease Pet127. Involved in the specific removal of group I introns in mitochondrial encoded transcripts.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Binds to mitochondrial small subunit 15S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCM1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697384">
        <property type="protein sequence ID" value="EFQ34840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008098860.1">
        <property type="nucleotide sequence ID" value="XM_008100669.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QVF2"/>
    <dbReference type="STRING" id="645133.E3QVF2"/>
    <dbReference type="GeneID" id="24415349"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_09984"/>
    <dbReference type="eggNOG" id="KOG4197">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012630_1_1_1"/>
    <dbReference type="OrthoDB" id="1908178at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031930">
        <property type="term" value="P:mitochondria-nucleus signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47936:SF1">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN GUN1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47936">
        <property type="entry name" value="PPR_LONG DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="226"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ34840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="510" mass="58706" checksum="5DA75F0234490E3D" modified="2011-01-11" version="1">MSSTASHPMFTDGLVAAVDLSAGALESPPFYNSEKSAFRKRKRQLLSFMDHRDVGTVDEYLELVDDPFLNRYAQPEHAKLTISDEGDDTRCLPLNEYLGDKTTAQIAHTLAIILNRRLRTKRGSVNEIYETYTALPEPRMIYLRKRCRHRLLKVCGRQSRQGIKQMLRYFSLIEDVKDCGISIRRNEWNYALAAATKFAGKTTEAEAEFALQLWKEMEAHKRATSNSVTFNILFDAASKSGNYILADMLYKEMKARGIPFNRYHHVSLIHFFGLQEDADGVRAAYKEMVQAGETVDTVVLNCIIFGFLKCGEDNAVLRVYEYMKETHSKHVITKPSTTEVDLQSQQQQIADVTPDLRTFRILINHFGVQRGDLAQVAIFLNEMRAFKIPMHGSIFLALFQGFMRYGNVIFSEWTPARLENILSALLQALDNQVQGLYLDTWLMMWALRAFMKCTNKERTMEVYEEFGKRWDLAPDKVDHMESYVARLLDDKNLMPSLKDMPQAVRQRRPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>E3QW06</accession>
    <name>E3QW06_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="18">RNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">GLRG_10188</name>
    </gene>
    <organism evidence="19">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">RNA-dependent helicase required for nonsense-mediated decay (NMD) of aberrant mRNAs containing premature stop codons and modulates the expression level of normal mRNAs. Also capable of unwinding double-stranded DNA and translocating on single-stranded DNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA2/NAM7 helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697387">
        <property type="protein sequence ID" value="EFQ35044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099064.1">
        <property type="nucleotide sequence ID" value="XM_008100873.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QW06"/>
    <dbReference type="STRING" id="645133.E3QW06"/>
    <dbReference type="GeneID" id="24415553"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10188"/>
    <dbReference type="eggNOG" id="KOG1802">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001666_4_0_1"/>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:DNA binding"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="F:DNA helicase activity"/>
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        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:RNA binding"/>
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        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21407">
        <property type="entry name" value="1B_UPF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18039">
        <property type="entry name" value="DEXXQc_UPF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21400">
        <property type="entry name" value="ZBD_UPF1-like"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Regulator of nonsense transcripts 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Regulator of nonsense transcripts 1"/>
        <property type="match status" value="1"/>
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    <dbReference type="Gene3D" id="2.40.30.230">
        <property type="match status" value="1"/>
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    <dbReference type="Gene3D" id="6.10.140.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
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        <property type="entry name" value="DNA2/NAM7-like"/>
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    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040812">
        <property type="entry name" value="UPF1_1B_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018999">
        <property type="entry name" value="UPF1_CH/ZBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF364">
        <property type="entry name" value="REGULATOR OF NONSENSE TRANSCRIPTS 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18141">
        <property type="entry name" value="UPF1_1B_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09416">
        <property type="entry name" value="UPF1_Zn_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51997">
        <property type="entry name" value="UPF1_CH_RICH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 18" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0866">Nonsense-mediated mRNA decay</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 15" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 15" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Upf1" evidence="17">
        <location>
            <begin position="88"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="44"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="C3H" evidence="15">
        <location>
            <begin position="96"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="CC/SHH/C" evidence="15">
        <location>
            <begin position="110"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="C4" evidence="15">
        <location>
            <begin position="156"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="904"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="52"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
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    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
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    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00055561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EFQ35044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1086" mass="119406" checksum="DCD62E5E974D6E3B" modified="2011-01-11" version="1">MEGAFNHLGNHLLSDSAAAIKAGADDLTGIEPDESFLYGKFGGRGARRRADDDDNQTELYDDDDNDSLTSMPVGATKDLNLGRPQDEDRELPPHACAYCGIHSPSSVVKCLGCNKWFCSARSNASSSHIVNHLVRARHKEVQLHPESTLGDTVLECYNCGTKNVFLLGFIPAKSDTVVVLLCRQPCAANTSSKDMSWDTSRWQPLIEERAFLTWLVATPSDAEQLRARHLTPPMIAKLEEMWKENATATVADLEKAASIDDDPHPVLLKYDDPYHYQNIFGPLVKMESDYDKKLKEAQSEDGLTVRWDYGLNNKHLVSFELHKIESGDVKLAVGDEMRLRYKGELRPTWEGVGYVIKIPNNQSDEVTLELRKAGNEKTVPTECTHNFSADYVWKATSYDRMQYAMKTFAVDDMSVSGYIFHKLLGHDVAVAPMKTTMPKKYSVPGLPDLNTSQIAAIKAVLSTPLSLIQGPPGTGKTVTSATIIYHLCKMNNGQVLVCAPSNVAVDQLCERIHRTGLKVVRLTAKSREDVESSVSFLALHEQVRMNDSNGELVKLAQLKSELGELSSQDEKKFKQLTKAAERDILHNADVVCCTCVGAGDPRLSKMKFRNVLIDESTQSAEPECMIPLVLGCKQVVLVGDHKQLGPVIMNKKAAKAGLNQSLFERLVNLRLVPIRLNIQYRMHPCLSEFPSNMFYDGSLQNGVTVRERVRRDVDFPWPVVDMPMMFWSNLGNEEISASGTSYLNRTEASNVEKVVTRFFKAGVKPLDIGVITPYEGQRSYIVSTMQNTGTFKKESYKEVEVASVDAFQGREKDFIVLSCVRSNDNQGIGFLSDPRRLNVALTRAKYGLVIIGNPKVLSKHELWHHLLVHFKDRKCLVEGPLTNLQTSLLQFGKPRTAYRQKMSQPPQFNAGAPPNGTNRFNGAGSTRDFDSGSLISYIPDDVSSIHSSLGGAGLNTTYPPIFSSFAPDQWPGLPGVPGTGRSGNKRGGRATESIAGESVANSEYTDASASVIGAKGVGQGGVSLGAGLQDAIHGMRPASYSHSDRLKHYVESGGRVGAGNGFGRRYDDDEKSVSTAFHSQIGGGFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWC2</accession>
    <name>E3QWC2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_10304</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697389">
        <property type="protein sequence ID" value="EFQ35160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099180.1">
        <property type="nucleotide sequence ID" value="XM_008100989.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWC2"/>
    <dbReference type="STRING" id="645133.E3QWC2"/>
    <dbReference type="GeneID" id="24415669"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10304"/>
    <dbReference type="eggNOG" id="ENOG502SH73">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007091_1_0_1"/>
    <dbReference type="OrthoDB" id="4236860at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051430">
        <property type="entry name" value="Fungal_TF_Env_Response"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31944">
        <property type="entry name" value="HEME-RESPONSIVE ZINC FINGER TRANSCRIPTION FACTOR HAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31944:SF130">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTO (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="35"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="139"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="453"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="139"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ35160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="793" mass="90884" checksum="DAA3317D56F1796F" modified="2011-01-11" version="1">MSPSVDEAGSLSPTNSRDDDENSQHPRKRQRVRLSCLECRRRKLSCDRGYPCQRCLKSGTPDRCTYETKSGVVLNASSGVPPAFAQLDSRRNGELVMPGKEADMSVIREAAKDHDRIRRLELEVSQLKTQLTRQVMSSFDGSTIAGTNSPHTQKDDIGETPPDPCANNSELQSCWHQYSDGDKSELRFFRGKEFRTRYFGPHNATMAFIELTGLCPFMKETADEWLKPVKAHDRKDRKKRKEDRDKFYLQPDPHLESLLPPKDHCDALVEVYIDQFEQMHRIVHIPTFRREYSQFWENPTESRYAALTALVLAICAVTNCIHTHESLRFTGMISNAHAAAEKWIKAVEEWQSRQSMKHRKLIHYQIACLLYLSKRVNTLKKKRFWTNSGALIQDGISVGLHREPSHMSGKISVYNQEMRRRIWATVQEFDMQASFDHGLPTLVSQLHYDVQPPRNLDDEDFDEDTTQLPPSKHGKEYTYSSYQNLARQSLPLRMELSRLLCGPPGEIDYDQVIRYTNDITHEIDSLPSWEHNNNNTHGGKRPLLAYTLLHIQLRQYIIPLHQPFLKLRKSNAKYQYSEIIYYNAARDIVLLHDKLYEQGIRCLNFLREDALTTAVNLCSVTMLQPRGSTNMIMINSQHTVKLLEKCLSMKEDRLLRCGNTEPWGYSIMCSALGLLEAHLGTKTTEQAKASSAERFVNLHYKLLANQEPPVSSQPSELSKIPGLEVPERSKSVTPFSFQGYPPSQNPVDGLLPQPLPWMSASIEPQAQSFNPDFSLEALGLNLNELWGESWDFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWE0</accession>
    <name>E3QWE0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hydantoinase B/oxoprolinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_10322</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxoprolinase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697389">
        <property type="protein sequence ID" value="EFQ35178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099198.1">
        <property type="nucleotide sequence ID" value="XM_008101007.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QWE0"/>
    <dbReference type="GeneID" id="24415687"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10322"/>
    <dbReference type="eggNOG" id="KOG1939">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002157_0_1_1"/>
    <dbReference type="OrthoDB" id="3643at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017168">
        <property type="term" value="F:5-oxoprolinase (ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008040">
        <property type="entry name" value="Hydant_A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002821">
        <property type="entry name" value="Hydantoinase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003692">
        <property type="entry name" value="Hydantoinase_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045079">
        <property type="entry name" value="Oxoprolinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365:SF2">
        <property type="entry name" value="5-OXOPROLINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365">
        <property type="entry name" value="5-OXOPROLINASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05378">
        <property type="entry name" value="Hydant_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01968">
        <property type="entry name" value="Hydantoinase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02538">
        <property type="entry name" value="Hydantoinase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydantoinase/oxoprolinase N-terminal" evidence="4">
        <location>
            <begin position="12"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="Hydantoinase A/oxoprolinase" evidence="2">
        <location>
            <begin position="244"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="Hydantoinase B/oxoprolinase" evidence="3">
        <location>
            <begin position="728"/>
            <end position="1250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ35178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1282" mass="136861" checksum="66AFC5C612C9BFA2" modified="2011-01-11" version="1">MGSLPGPVQGIRISIDRGGTFTDCVASVPGQDDILVKLLSVDPGNYPDAPVEAIRRVLEKATGRAYPRGKKISLRGVESIKMGTTVATNALLERKGERTVFAVTKGLKDLLHIGNQSRPKLFDLAIRKPDVLYSKVIEIPERVTLEAWSENNKPDVIDVSSDPALVTGVTGEVVRVLEPLDLEASRKALQEAYDEGYRSIAVCLMHSYTFREHEAAVADLAADIGFTHVSPSAELSPVVKIVPRGNSSTADAYLTPEIKRYIAGFESGFEDLATSGCRCEFMQSDGGLVEFSGLSGLRAILSGPAGGVVGYARTCFDETDKTPVIGFDMGGTSTDVSRYAGELEQVFETTTAGVMVQTPQLDINTVAAGGGSILSWQSGMFKVGPESASAHPGPACYRKGGPLTVTDANVVLGRVRPEFFPKIFGLNEDLPLDVDASRRLFEDLTASINKDENTNLSVEEVAAGFLDVANESMCRPIRTLTEAKGYDAGLHNLASFGGAGGQHACDIAKTLGISRVLVHKYSSVLSAYGMALADVVREERSPCALTYDEANRAVFAAELDKLVAKAGDALLLQRIPRDRIVPERYLNMRFQGSDTPLMIQETARPGGYLAAFRDEHQKQFGFLPVGREVIVDDYRVRAVGKTTVQLPTPWPEELASAEAAPSPPPPAAKITKPVYFKGLGWIAGPALVMDDKQTIVVIPGAAATVLSETVVVDVAVGTRETISATAVDPIQLSIFGHRFMGVAEQAGRALQKTSVSTNIKERLDFSCTVFSPDGGLVANAPHVPAMIGSMAYAVKWQIDHWGEDLKPGDVILSNAPVCGGTHLPDLTVITPVFDAEGKKIMFWTASRGHHADVGGILPGSMPPNSKELWEEGAVIKAFKVVEGGVFKEKELIDLLMAPAHHPGCSGTRCLRDNISDIKAQAAANHRGSQLIHSLIDDYGLDVVQFYMEGIQGAAERAVRDMLKTIHKRTAGKPLSAVDYMDDGTPIQLEVTIDPATGGAVFDFSGTGPEAYGNWNAPIAICNSSIIFALRCMVDAEIPLNQGAIRPVEVRVPEASLLRPTEHAAVCAGNVLTSQRVVDVIFRAFGAAAASQGCMNNLTFGTDDPDSGFGYYETICGGAGGGPTWDGASGVHTNMTNTRITDPESLERRYPVVLRRFCLREGSGGRGAHMGGDGVVRDMEFGIPIKVSILSERRAFAPYGMAGGEDGQRGRNVWVKKSGRVVNLGGKNTARMEAGDRIIIMSPGGGGYGRPEDRVEVGGKQPKGFVGVANGTVDMIQSMGESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWE1</accession>
    <name>E3QWE1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aldehyde dehydrogenase</fullName>
            <ecNumber evidence="3">1.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_10323</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>an aldehyde + NAD(+) + H2O = a carboxylate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:16185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="GG697389">
        <property type="protein sequence ID" value="EFQ35179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099199.1">
        <property type="nucleotide sequence ID" value="XM_008101008.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWE1"/>
    <dbReference type="STRING" id="645133.E3QWE1"/>
    <dbReference type="GeneID" id="24415688"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10323"/>
    <dbReference type="eggNOG" id="KOG2450">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_0_2_1"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019413">
        <property type="term" value="P:acetate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07091">
        <property type="entry name" value="ALDH_F1-2_Ald2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000050">
        <property type="entry name" value="Aldehyde dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000026">
        <property type="entry name" value="Aldehyde dehydrogenase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000001">
        <property type="entry name" value="Mitochondrial aldehyde dehydrogenase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="8">
        <location>
            <begin position="27"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ35179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="496" mass="53768" checksum="713D6BC6CED493D2" modified="2011-01-11" version="1">MGLSVELKTPATGPYTQPTGLFINNEWVEGVDKQTFEVINPSTEEVITSVHEATEKDVDIAVAAARKAFEGEWRQIPPSQRGVLMGKLADLAEKNTDLLAAVESLDNGKSISMAKGDVSAVVGCIRYYAGWADKIEGKTIDVAPDMFHYTRPEPIGVCAQIIPWNFPLLMLAWKIGPALATGNTIVMKTAEQTPLSALVFANLVKEAGFPPGVFNLINGFGKVAGAALSAHMDVDKIAFTGSTLVGRQIMKAAASSNLKKVTLELGGKSPNIVFDDADIEQAISWVNFGIYYNHGQCCCAGTRIFVQESIYDKFLAAFKKRAEQNKVGDPFHPETFQGPQVSQLQFDRIMGYIKAGKDEGATVETGGARHGDKGYFIQPTIFSNVRPDMKIMQEEIFGPVCAIAKFKDEDEVIKLGNDTTYGLAAAVHTTNLNRAIRVSNALKAGTVWVNCYNMLTYQVPFGGFKESGIGRELGEAALANYTQNKSVAIRMGGPLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWE7</accession>
    <name>E3QWE7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Elongin-C</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_10329</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Controls sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SKP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697389">
        <property type="protein sequence ID" value="EFQ35185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099205.1">
        <property type="nucleotide sequence ID" value="XM_008101014.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWE7"/>
    <dbReference type="STRING" id="645133.E3QWE7"/>
    <dbReference type="GeneID" id="24415694"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10329"/>
    <dbReference type="eggNOG" id="KOG3473">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_130038_1_0_1"/>
    <dbReference type="OrthoDB" id="249087at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18321">
        <property type="entry name" value="BTB_POZ_EloC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.710.10:FF:000035">
        <property type="entry name" value="Elongin C transcription elongation factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039948">
        <property type="entry name" value="ELC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001232">
        <property type="entry name" value="SKP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016073">
        <property type="entry name" value="Skp1_comp_POZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20648">
        <property type="entry name" value="ELONGIN-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03931">
        <property type="entry name" value="Skp1_POZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00512">
        <property type="entry name" value="Skp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SKP1 component POZ" evidence="6">
        <location>
            <begin position="11"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00045385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ35185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="112" mass="12716" checksum="C4E05F85418CEB2D" modified="2011-01-11" version="1">MDANGATESKYVTLVSSDGYEFVVLREAAMISPAIKGMLDTRNNFREAALGRCVFEEISGVVLEKVCEYFQYWYRYREREDVPDMDIPVELCLELLVAADYLGLDKQNTGTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>E3QWQ5</accession>
    <name>E3QWQ5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10437</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697390">
        <property type="protein sequence ID" value="EFQ35293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099313.1">
        <property type="nucleotide sequence ID" value="XM_008101122.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QWQ5"/>
    <dbReference type="GeneID" id="24415802"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10437"/>
    <dbReference type="eggNOG" id="ENOG502SA1F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058677_2_0_1"/>
    <dbReference type="OrthoDB" id="5384020at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="61"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="229"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="294" mass="30996" checksum="43B9850F0787BB10" modified="2011-01-11" version="1">MSTDNSNPNTQNNQNEMHRQRRGSVTQQAIAGLFRSNSTSNGAAFPGTADAQRRRLSVSTGLGLAGTTPTPGGPFNSLRRGSLSTNSNDSIDENAIDEEEMPSNARTAPTTPFTRRVSFGAQAMRTMRTGGGSPGSNGNNPPVSATPLPSTPASCDRRSSTAVNATPSIYSIAAAPSSVRCRSSSIAQASTAHKQMSISDMFSCPDQGFNWSEQFRSRAESSVQGTRPSFSFGSGLSSSPTRGTGNAGAHDRQKSVSEMPAPPAQAAAMKPKAPERPKPDAFQERILKGDFYMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QX34</accession>
    <name>E3QX34_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_10566</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697392">
        <property type="protein sequence ID" value="EFQ35422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099442.1">
        <property type="nucleotide sequence ID" value="XM_008101251.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QX34"/>
    <dbReference type="GeneID" id="24415931"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10566"/>
    <dbReference type="eggNOG" id="ENOG502T428">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_647243_0_0_1"/>
    <dbReference type="OrthoDB" id="4817623at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ35422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="393" mass="43841" checksum="BA5F6FE64A310649" modified="2011-01-11" version="1">MACAPAVEQEQTGVTMTSVWKSIDAPRSTFEVENSTFFLPAGPTAGDKFWMVLASGDIGFVTKNGFLSEDSGVQSSVKRKDRRKGFTFHCGTLTINFHPSSPFRRCFVGHGAMAEKRVVARLRTDCQYAADKVAGCMASMLWHRVESDGSATWPTEREVADDLKKAVGALSELVEFAARFVEVMKRQYQGGGREETMPVAYGKAVKLLGLAEWHRIHRTLNAAQCMEKAFRQSVGRSASRATRQRCENFIQSNLLGMLGWRLAPWSMGSQRNVLRDGLTALDVLGATDWDCFEAEGVRGRMDKSSTTVRIVKEADFAIWTHQKLMRFLRHQPLRAVDLEEARWAGKESRSQEVIHPVHLRVLRALPWVKTFDVAGHVPILRLVVLDSVDGAGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXB3</accession>
    <name>E3QXB3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1479 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10645</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697394">
        <property type="protein sequence ID" value="EFQ35501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099521.1">
        <property type="nucleotide sequence ID" value="XM_008101330.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXB3"/>
    <dbReference type="STRING" id="645133.E3QXB3"/>
    <dbReference type="GeneID" id="24416010"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10645"/>
    <dbReference type="eggNOG" id="ENOG502QWFN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011148_3_0_1"/>
    <dbReference type="OrthoDB" id="8249012at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010856">
        <property type="entry name" value="Gig2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30613:SF1">
        <property type="entry name" value="DUF1479 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G09280)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30613">
        <property type="entry name" value="UNCHARACTERIZED PROTEIN YBIU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07350">
        <property type="entry name" value="Gig2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="627"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="681"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="728"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="60"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="97"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="138"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="755" mass="79183" checksum="9413E8F8C18524AB" modified="2011-01-11" version="1">MILARLASGPTEALPANGEGGKGGGDGDVGGGGGGGGGGPVGVGVGTVGDSGNTVILTGPASSRASSSTSTPAATAPSVKSPTSGLGRKSRRGLGSGARTGSSSSSGSGGSISGGGVGGGGGGGGGGGRRTSSRVLKTTPPSSTAVSRATSVSPTSALLTPPLSTAATTAATTRSSTSTPAAVAAAASRKVFPKSMEPPVVSFYGAEPIPLPSRFAGVKKRLIAGHEAAVEASWRRLLDALRTEIADIQDRGSELIPSINFTDINDPVRVEAFAHRLRRYGVAVIRGVVSPNDARGWVQETHEYLDKNREFKPPALHDPTCIDLFWTPVQVRARAHPNMLRAQKFAMSFWESTDDLHITRAPVSYADRLRIHNDKLGAVGQRSGNSAADSLSATASSTVIAQIDSGSLERWEPDGYGRGGTYEAVFRGDWESYDPWDPAGRVGATTDLYNGEGACSVFRMFQGILALTKVEQGMVRVLPSPKLVAAYFLLRPFFSPKRGPPEQPDGGKADQWAAYLDASNWALDPEPNTIIHGAVPGHAQRLTERWHPHLHLRRSLVSLPSLRAGDYVIWHCDQAYSIITGGTRLGVPQALQNESNELSLLTYTPVCPLTQTNALFLARQRKAFQTGQPGPDFDTLGGLGSEASHQDRPGAREVEEYGGVDGLRAMGLAPYDVEPAGAPPKHADAMDVDNEDNEGVRNRTKTEAETELLRLANIILFPSRYDFYIPTSGTRGSGDRTPRAVAGGAPKTMVNGNKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXC1</accession>
    <name>E3QXC1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">L-ascorbate oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_10653</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697394">
        <property type="protein sequence ID" value="EFQ35509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099529.1">
        <property type="nucleotide sequence ID" value="XM_008101338.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXC1"/>
    <dbReference type="STRING" id="645133.E3QXC1"/>
    <dbReference type="GeneID" id="24416018"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10653"/>
    <dbReference type="eggNOG" id="KOG1263">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006504_8_3_1"/>
    <dbReference type="OrthoDB" id="2121828at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13873">
        <property type="entry name" value="CuRO_2_AAO_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13895">
        <property type="entry name" value="CuRO_3_AAO_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
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        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035666">
        <property type="entry name" value="MCO_CuRO_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017762">
        <property type="entry name" value="Multicopper_oxidase_fun"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03390">
        <property type="entry name" value="ascorbOXfungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF394">
        <property type="entry name" value="FI03373P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0186">Copper</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180944" evidence="7">
        <location>
            <begin position="20"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="10">
        <location>
            <begin position="51"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="8">
        <location>
            <begin position="176"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="9">
        <location>
            <begin position="426"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="SignalP"/>
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    </evidence>
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            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
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            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EFQ35509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="601" mass="67411" checksum="57E997713362B4BC" modified="2011-01-11" version="1">MHSFVLFSWLLALLSQAYAWGPRRSSYGPPGHYGGLHTHDSSFVPDHVLRLTYENVSVGCQTRQSVLVNGSLVGPALRLRPEERSWIRVYNDMEEFNTTMHWHGLSMRMSPFSDGSPTAAQWPIPPNHFFDYEIFPLKSESGTYFYHSHVGFQAATMSGPLIIEDEEEPPYAYDEERIVYLTDYFNKTDSDIEAGLMGSPFTWSGETNAVLINGVGVAIGETAGQGDCALPVIDVEPGKTYRLRFIGATALSMVQMGIMGHDNLTIIEVDGSYTKPHTEKFMQLSTGQRFDVILQAKTEEELQGTTDYLIQLETKERPQVYHGYGVLRYSGAPPQISTAPDVPPLTFSNKTYEWAEYAFEPMEADDFPLASEVTRRIHIDSRQLSTQSIRWQLNGLEWNETSSPYPGDKPYLVNIYENGPSAIPNYTAAIENNGWDPATLTWPAKMGEVLEIIWHNTGSLVDGNGGLDFHPLHAHGGHYWDIGSGNGTYDSDENEEKLKNYNPIKRDTTNLYRYAEKTTSGDLSGWRGWRLRVKDAGVWMIHCHILQHMIMGMQTVWVMGDYQDITGIPAVDAAGYLQYGGNVNGNATFAPSVVHLFDVDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXJ6</accession>
    <name>E3QXJ6_COLGM</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10728</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="GeneID" id="24416093"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10728"/>
    <dbReference type="HOGENOM" id="CLU_3032241_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="55" mass="6329" checksum="445BCB5F8AE4212A" modified="2011-01-11" version="1">MQKKLKRIPDASSHVRHSHNSAAEPPAWRGHRQRFASDSPEYVAMDSFKQHQSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>E3QXR8</accession>
    <name>E3QXR8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_10815</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697397">
        <property type="protein sequence ID" value="EFQ35671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008099691.1">
        <property type="nucleotide sequence ID" value="XM_008101500.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QXR8"/>
    <dbReference type="GeneID" id="24416180"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_10815"/>
    <dbReference type="HOGENOM" id="CLU_2072962_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ35671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="118" mass="12340" checksum="EF9B9380D20C3D38" modified="2011-01-11" version="1">MSRLEPCGPGTDGDPTRRYVRRQPGGSCPLIPDPAPGSGSGGGNGQTDSFTSGPQPSPTFAAAGACGGTFCEGFWCNPRPTSVPPDERAPRLPRPQGPQQQWIVRLDPDHLGPPRGHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZ67</accession>
    <name>E3QZ67_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_11299</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697411">
        <property type="protein sequence ID" value="EFQ36155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100175.1">
        <property type="nucleotide sequence ID" value="XM_008101984.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZ67"/>
    <dbReference type="GeneID" id="24416664"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11299"/>
    <dbReference type="eggNOG" id="KOG0253">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_52_2_1"/>
    <dbReference type="OrthoDB" id="288590at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17316">
        <property type="entry name" value="MFS_SV2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511:SF5">
        <property type="entry name" value="MAJOR FACILITATOR-TYPE TRANSPORTER HXNZ-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511">
        <property type="entry name" value="SYNAPTIC VESICLE GLYCOPROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="369"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="408"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="436"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="495"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="525"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="74"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ36155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="552" mass="59524" checksum="663F78F8CDD942D7" modified="2011-01-11" version="1">MSAPSEKSVGKGATETGLRQTLSGSVQHGEADSDADSALREFYTGAVNENYRMKSELIAKHLGAIGMGKFQWILFVVNGFGWIVDNFWSQGITAIRPPIGNEFTDIARLSFSSVAYYVGLIIGASFWGTTADLIGRKPAFNATILYGGVFACAVAGVQNFTGFCILWAIIGTAAGGNVPVDSVVFLEFVPQTYQWLLVSLSAWWNLGQVIVSLLAWLFLSHFACPSTDAPCRMQNNMGWRYLMITLGGVAIAFGLIRIVAFKIPESPKFLISKGRDAEAVEAVNYIARYNGRPETLTLDMLQAIDRRCNGTTASDDCASSGVAPVDADVAPRGSKLSHMEILRESFKDYNADNYKKLFAGRKMAQHTSVTFLIWLTVGVAYPLYFAFIPSYLETKSSYSTNTSLGHTYMVYCIVSSAGVIGPIAAGFCVETRFGRRWMMAGSAVLTGVFLFAYTAVGTEAADIGFQCATAILGNFEYAIMYAFTPESFPGPVRGTGTGIAATLLRLGGLVASFVSTYAGYTVVPIYASAALWVLVGGFCFGLPYETHGHASI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZB5</accession>
    <name>E3QZB5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">KilA-N domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_11348</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697414">
        <property type="protein sequence ID" value="EFQ36203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100223.1">
        <property type="nucleotide sequence ID" value="XM_008102032.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZB5"/>
    <dbReference type="STRING" id="645133.E3QZB5"/>
    <dbReference type="GeneID" id="24416712"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11348"/>
    <dbReference type="eggNOG" id="ENOG502S0ET">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030669_0_0_1"/>
    <dbReference type="OrthoDB" id="5346159at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990862">
        <property type="term" value="C:nuclear membrane complex Bqt3-Bqt4"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048315">
        <property type="term" value="P:conidium formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070197">
        <property type="term" value="P:meiotic attachment of telomere to nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044820">
        <property type="term" value="P:mitotic telomere tethering at nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030435">
        <property type="term" value="P:sporulation resulting in formation of a cellular spore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.260.10:FF:000002">
        <property type="entry name" value="APSES transcription factor, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.260.10">
        <property type="entry name" value="Transcription regulator HTH, APSES-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037548">
        <property type="entry name" value="Bqt4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036887">
        <property type="entry name" value="HTH_APSES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018004">
        <property type="entry name" value="KilA/APSES_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003163">
        <property type="entry name" value="Tscrpt_reg_HTH_APSES-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38044">
        <property type="entry name" value="BOUQUET FORMATION PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38044:SF1">
        <property type="entry name" value="BOUQUET FORMATION PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01252">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54616">
        <property type="entry name" value="DNA-binding domain of Mlu1-box binding protein MBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51299">
        <property type="entry name" value="HTH_APSES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0183">Conidiation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0749">Sporulation</keyword>
    <feature type="domain" description="HTH APSES-type" evidence="5">
        <location>
            <begin position="62"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="186"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="268"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="342"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="198"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="280"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="311"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="359"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="370"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ36203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="417" mass="45425" checksum="979E6CE56C0686FF" modified="2011-01-11" version="1">MPSATAPERHLPAKHNPLMLEDVPSYNDLVARRRLGQTQLNAKMVNHADGEGAALGVFDYAHLRAPLPKGIVSGIFKSSPNSYFLMRRSYDGFVSATGMFKATFPYAEASEEEAERKYIKSLATTSPEETAGNVWIPPEHALILAEEYSIAPWIRALLDPANIAVSNSPDSPPKRITAPPKFDLFKVHPQLAPPTPASLPRSTRSRRSASPTKTAAPRPVRSPRKRRTKADSVEPRESTPTLTTATKLQVNGIIDEDRDAEARVETAIKTIETEPAAAPEPKKQDTKAKIFVDQDLKTDEDGNETKRTAVSLELPLLSSAPPTAEETARMIAEAKQMVEAAGIKSDEGVDSPQVKKGKRSAEEISKGDDEDKEQDGEVDSAEEPRAKKAKTAEVQVKKLRVRNRALFGLSAVSLAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZF1</accession>
    <name>E3QZF1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="2">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_11384</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11 12">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="2"/>
    <dbReference type="EMBL" id="GG697415">
        <property type="protein sequence ID" value="EFQ36239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100259.1">
        <property type="nucleotide sequence ID" value="XM_008102068.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZF1"/>
    <dbReference type="STRING" id="645133.E3QZF1"/>
    <dbReference type="GeneID" id="24416748"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11384"/>
    <dbReference type="eggNOG" id="KOG1863">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003155_0_1_1"/>
    <dbReference type="OrthoDB" id="2420415at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061136">
        <property type="term" value="P:regulation of proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02666">
        <property type="entry name" value="Peptidase_C19J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044635">
        <property type="entry name" value="UBP14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025305">
        <property type="entry name" value="UCH_repeat_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982:SF6">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13446">
        <property type="entry name" value="RPT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="8">
        <location>
            <begin position="585"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="560"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="712"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1180"/>
            <end position="1242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="564"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="714"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1216"/>
            <end position="1236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ36239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1242" mass="139116" checksum="0282BF34E28919DB" modified="2011-01-11" version="1">MAISDQYSIMSPSDSPTAEHWEGRPALVKENMLGKTGRLAPRWVQDLLNSDLDSGSFIRIEWDREARCSNTGVPHRLVLVGNQSTAESRNPGVLSCVCCNCDFHFIIRTSWDPDHLVCLCRPQNLHFPPKDTDFYIHHLVNVKVATRPAKPVSDYHPMIREALLAVEHFSCSAPRCTFQVSVEISRPRLKREWVRLLLDKQRILDNLARARKISPERFADARDDWSTSAPSTLNTYLRDLLDKPSPRNISRRNKRFQVVFGDECYDIFRAIQFTEENLDKDGVFEPYFIPPVLEPGTPGIPTKLNTLRAFIEDLQAEAESLIIRSGKPGETRPYVGNRLFKELQCFEYPQNTVSQSATNAHRVLGVLPDFDKALIFFAYNRQSALCEKRRQTYVEALRDIALLTADEDFQTRAIQELTIVEGMDLSGTHSAGDELESQAYSFFSLKYTASDDNVISAYNTKLEHSPAQADFAKEMLQIIGRHRSSDRILTHANGPMDVSSAYRILEADPQWPDSTIVMMCSVKLNKDPRSKAIAEVAIKAMEAIASDRNSDEIRQAVKALEQESGPSQQEKAESLPSTTTTNLPVGLENIGNTCYLNSILQYLNTVVPIKDLLAHYPMHELGLDDSDIQRRLIGGNKLKIDRAEAVVARVFVEELGRLLNNLGSSQAPAIRPSQRLANAVLLPTSNLTEGPIPQQKAKDTAEPKTLEVMGAQFPAPPPLPARPPPGPPKQQPGQTEDVDMVNVTVDPVSETASSVSSQTLVNMSDVDGEKRDYVTEDKTDIRIVSHPVEASAPEPAINSDMNMTGVETPSLNVEQRVLKALETQTRTSGTEQQDVEEVMGSIINRLQAAIKPTKTDATDGIQWEPIMETFYVELTNHTKFPNQDKYKLDSTLERAITAYPAETGPTNIHDGLSRNFDLQRVVAGKEDIMRFTSIKRLPPILHVLIQRTQNNGNKNMNPVEVFETLYLDRYMDTPDDPQFFKLRQKGWALQQRLEQLNSIPTITAEDAEVIDSFVNDFVHVNKADIPEPESLLGGLPTSSLDFAGEDSSFPTYNLSDTSFNKSDPPSTTGFTADGRQQINNMRVEEVKAYKAELEELFSQHKKHAYRLHAVICHSGQLRAGHYWVWIHDFEAGVWRKYNDRTVTETPNTEEVLKTLNSNGDPYYLCYVQDGRERELVKVPKRSLPDPPISGQGSNANKDVSKDADGDIDLIDMGNLTADTQATSKTSPTTGELSINTVERDQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZM6</accession>
    <name>E3QZM6_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Kinesin motor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_11459</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697418">
        <property type="protein sequence ID" value="EFQ36314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100334.1">
        <property type="nucleotide sequence ID" value="XM_008102143.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QZM6"/>
    <dbReference type="GeneID" id="24416823"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11459"/>
    <dbReference type="eggNOG" id="KOG0244">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_241013_0_0_1"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005875">
        <property type="term" value="C:microtubule associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051231">
        <property type="term" value="P:spindle elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01372">
        <property type="entry name" value="KISc_KIF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000125">
        <property type="entry name" value="Kinesin class 4 (Chromokinesin group)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969:SF15">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0505">Motor protein</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="9">
        <location>
            <begin position="52"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="182"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="474"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="771"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="863"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1588"/>
            <end position="1655"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="669"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="813"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="960"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="1056"/>
            <end position="1156"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="1196"/>
            <end position="1399"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="1441"/>
            <end position="1563"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="1670"/>
            <end position="1765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="26"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="863"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="877"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="906"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="929"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1588"/>
            <end position="1602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="1612"/>
            <end position="1624"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="139"/>
            <end position="146"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ36314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1774" mass="196541" checksum="5EB9F1947AAB14F3" modified="2011-01-11" version="1">MASSPPASPGNHLTQRPMSAMVRPSPRSNSRMSTTSRQGGGSKASDEDIRTAVKVAVRVRPPLNPNDPGYDLIPQRFQRSMVQVTSDTSLAIDSPQGKKLFVFDRVFGSDVDQEGVWDYLNDCVTAFIQGYNVSLLAYGQSGAGKSYTMGTSGPSEQGDVEMMGVIPRAATALFEMLDGTKKPTNRGSMSHLRTPARYSSHASQPSADKNWSLKATYLEIYNEQLRDLLVPDHVPQNERSAVTIREDVKGNIILTGLRQVEINSVDDLMNALEFGSTLRQTDATAINARSSRSHAVFSLNLVQRKSGLHGSNGGDKRFSVPIEAMTGSETWVTTDSKLHFVDLAGSERLKNTGAQGERAKEGISINAGLAALGKVISQLSSRQPGSHVSYRDSRLTRLLQDSLGGNAITYMIACVTPAEFHLSETLNTVQYAQRARAIQSKPRIQQVEEGDKQAIIDRLKAEVAFLREQVRSAERGGGERRMASTGDRSERHYEREHELQNQLLDAQENYTTLSQRHAKLIAEMARARDNEAAENDQHEESMDDTATERLNRSNSFAAAVEQVVLEYEKTIQTLEQSLSSTRGTLASTEASLLEKETKCTYVETINTQLQARLQKLMDREASTENYLHDLESKLDGHTSGEEKNATIVMELRKEIARVRENEASCEDYISTLEERLAEADQDAELMQREIDRLEQVIERQRSLGKLDSLLHELDHIQGDSKVPEPVTETSNGVVRANGDHARNQSLSRISRMSQNDVIPENVEGEAAATAEAAHSARVDKQGGNDTDAETTLARERNLVPDKYDFPPPSPAQSKFVQDKLENVTQELIDLRVEHETTVNEYDLLHAKYEEALRTLADLQDTIDESRHPERKVRDSMMSVTSPTRTRPPSFFSDARSSGMKDGGPFSSRSLSSELSSALDSPAMIDPSDAETTGTAKPSSTEDLLHQDLLATEVERFRMLAAEKEGAEKELAERYIQLEQKHHEALDMLEELKTEVAQAKALDVSSPRASQPVIRRKSSQNVMIIDRAHRSFASLRNIAAENFEGQPDVMQNFELNLNAAMHELHARSERIQELEADVASTKKEMETKMALISGLTRERSSLKASPMDMSMVSNLKNQLEVNEQQMAAMRESHEATEKKLSAELESLRATLNRTRKEDVTTETLAASAAAGAVADVPAATTEVTETSQAAVDNDKKITELQTELSTWEAKHQNALDTLQETEAKMKMTIEELESEIRSLNAKVAEQSSAPDAEGIKDVGAKHETLLKSLREEIDEYKLAISTNAGKVSDLEAAHAATKAELEEAIRARDLHETQAKTQHSLITNLENQIAAHEQALKTHQESMKLLQENHAREVEEVRQAEQKGYEEQVAVLLNEHAENIRALEGELNDAREDLMKVATQVAYALGKDVSIEKLTQRIGVLIADQKALGETRKRYGEVEQHVIELSAINDNLLRELEQAKSTLSDILIAEGDAVASPVPLPAQLSAIRKKITDLESRNKKNSRLVEELEDQLQSNFDEVQMTNNRLSTLQTERNVQIEEAQAAKSRAESELDSLRAEYAALQVSLAENTGPSGSRDANRSQARIDEASNFGQVQHPDSANSPLRKSASVSSLPSPPPAIPLPPLPGGGNNASGPNGTVPNTPTQAGRPGSKDNMGSINHIQEDQEARIRTIEKHLQAEKQLTQTLEEALTDLERQSNKVKADGDAWRKRCTELEMEIKELKDRPAPTPQPDNRWSLHAVEEERKKRQAAEAQQRLLEERMNALSKKKKKGSLNCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QZS0</accession>
    <name>E3QZS0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_11503</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the acetyltransferase family. RimJ subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697420">
        <property type="protein sequence ID" value="EFQ36358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100378.1">
        <property type="nucleotide sequence ID" value="XM_008102187.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QZS0"/>
    <dbReference type="GeneID" id="24416867"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11503"/>
    <dbReference type="HOGENOM" id="CLU_013985_3_6_1"/>
    <dbReference type="OrthoDB" id="630895at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051531">
        <property type="entry name" value="N-acetyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43792:SF8">
        <property type="entry name" value="[RIBOSOMAL PROTEIN US5]-ALANINE N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43792">
        <property type="entry name" value="GNAT FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00765)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="4">
        <location>
            <begin position="14"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ36358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="177" mass="20005" checksum="64631635BC545AF1" modified="2011-01-11" version="1">MEPFLVDNLTTERLRLRDFTPNDTLHIHCLESLPEIVQYQLYEPMTAADAAKYVERALDSLHANPRAVLELIVELKDSQQFIGRVGMSISHEKLHGDLWFSFLPAAQGHGYAAEAVQGLLSLVPKLNSLGIECDPKNAGCRKLATRLGFKEVRSVEKMFKSKGQWVGSVEYEKRLEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3R045</accession>
    <name>E3R045_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_11628</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697427">
        <property type="protein sequence ID" value="EFQ36483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100503.1">
        <property type="nucleotide sequence ID" value="XM_008102312.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R045"/>
    <dbReference type="STRING" id="645133.E3R045"/>
    <dbReference type="GeneID" id="24416992"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11628"/>
    <dbReference type="eggNOG" id="KOG1200">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_10_1"/>
    <dbReference type="OrthoDB" id="5840532at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF133">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ36483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="246" mass="25305" checksum="E7FCE8C611A0FB3C" modified="2011-01-11" version="1">MARFTSKIALVTSCASGSGAAIVRRLASEAAIVIAADKTGHEALAAELGDSVIPRHLDAASEDSIRDLEAYIRTAHGRLDILVNNTGMGGPRCPILDVTAADAAEVFRYNIHGAFLLLQLGLRFMTSQPTGGCIVLTASIAGLVGTPNSAPYAISKGAVIAMVKTAAVEYAKHGIRVNAVAPGPTAVPMVEALGEAATAGLRARIPQARLAEPREVAAVVAFLADDQDTGHVTGQVWCVDGGWTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3R092</accession>
    <name>E3R092_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_11689</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697435">
        <property type="protein sequence ID" value="EFQ36530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100550.1">
        <property type="nucleotide sequence ID" value="XM_008102359.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R092"/>
    <dbReference type="GeneID" id="24417053"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11689"/>
    <dbReference type="HOGENOM" id="CLU_880017_0_0_1"/>
    <dbReference type="OrthoDB" id="10532096at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ36530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="316" mass="35356" checksum="92957C43963F7B02" modified="2011-01-11" version="1">MAKQRSRSVGRVDRVMRARQLRRFHHHLQTVQPARPDLLERFTDEVLRDIDLLLDGGEWRDVPEGSEESVFEQNWDKLASLTSQLTHVKRWQAEKEAAAAAAADDGGDANKEQDAAGEQPETTKTAGDRASSATRGGGGGDCSAQHQGQLVKPSAAPQPRDFVKAAVNHTSTPQDDDDDDDDEKLKDAIRVEYHKYRDRYNRIPALYMGWLHAWRNASKKHRVVEATLKNVLAAEAKADSTRSAYFTMAQAQSGNVTKAQVDEAHSEWATAAAIHRSAYEAWDKAKKQLDKAEQDEEEAATAWERDAERRMARQTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0C8</accession>
    <name>E3R0C8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Pectate lyase</fullName>
            <ecNumber evidence="10">4.2.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_11725</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Eliminative cleavage of (1-&gt;4)-alpha-D-galacturonan to give oligosaccharides with 4-deoxy-alpha-D-galact-4-enuronosyl groups at their non-reducing ends.</text>
            <dbReference type="EC" id="4.2.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 10">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the polysaccharide lyase 3 family.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.2" evidence="10"/>
    <dbReference type="EMBL" id="GG697439">
        <property type="protein sequence ID" value="EFQ36566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100586.1">
        <property type="nucleotide sequence ID" value="XM_008102395.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0C8"/>
    <dbReference type="STRING" id="645133.E3R0C8"/>
    <dbReference type="GeneID" id="24417089"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11725"/>
    <dbReference type="eggNOG" id="ENOG502QU39">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044863_3_1_1"/>
    <dbReference type="OrthoDB" id="441042at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030570">
        <property type="term" value="F:pectate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004898">
        <property type="entry name" value="Pectate_lyase_PlyH/PlyE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33407">
        <property type="entry name" value="PECTATE LYASE F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33407:SF9">
        <property type="entry name" value="PECTATE LYASE F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03211">
        <property type="entry name" value="Pectate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0106">Calcium</keyword>
    <keyword evidence="8 10 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025095801" description="Pectate lyase" evidence="10">
        <location>
            <begin position="24"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU367009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ36566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="254" mass="25973" checksum="E1434FD44F8B49D1" modified="2011-01-11" version="1">MKFSAVIAAVSATAVFAAPGAESSPNNFGAVEKRASFPIPASKGTVTFKAPQSVSGTFDGGLKTYGRGVKCTGQVEGGNKDAVFILENGATLKNAIIGADQIEGVHCKGSCTIENVWWTAVCEDALTLKGDGNASVIGGGARSAEDKVIQHNGLGTVTIDGFTAVDFGKLYRSCGNCKTMGERNVVVKNVKAFNGKMLTGINSNKGDTSSITGTCATSVKEICSEFQGTTPGHEPKKTSTGASASCKISAVKAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0P7</accession>
    <name>E3R0P7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Indoleamine 2,3-dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_11831</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the indoleamine 2,3-dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697467">
        <property type="protein sequence ID" value="EFQ36685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100705.1">
        <property type="nucleotide sequence ID" value="XM_008102514.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0P7"/>
    <dbReference type="STRING" id="645133.E3R0P7"/>
    <dbReference type="GeneID" id="24417194"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11831"/>
    <dbReference type="eggNOG" id="ENOG502QV6W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010089_0_1_1"/>
    <dbReference type="OrthoDB" id="540174at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033754">
        <property type="term" value="F:indoleamine 2,3-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034354">
        <property type="term" value="P:'de novo' NAD+ biosynthetic process from L-tryptophan"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:L-tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000898">
        <property type="entry name" value="Indolamine_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037217">
        <property type="entry name" value="Trp/Indoleamine_2_3_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28657">
        <property type="entry name" value="INDOLEAMINE 2,3-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28657:SF10">
        <property type="entry name" value="INDOLEAMINE 2,3-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01231">
        <property type="entry name" value="IDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140959">
        <property type="entry name" value="Indolic compounds 2,3-dioxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00876">
        <property type="entry name" value="IDO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="proximal binding residue" evidence="4">
        <location>
            <position position="373"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600898-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ36685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="438" mass="48809" checksum="425624430743080C" modified="2011-01-11" version="1">MSPHALPISPEIAQINVIPLRKYAITPNGFLPADAPLKVLSDPYFAPWERVIQHLPETLKTGKLRREVESLPVLSIDKLRNEAEYRRAYVILVFLAHAYVWGGKNAAEVLPPAVSVPLLRVSKALEVPPVATYAGLNLWNFWSNTDDLTDLDSLESLHTFTGTKDEAWFYLVSVAMEAQGARIITDTLNALESIKRRDYPAITSALDGLSANIRRIGALLERMYEHCNPMVFFYEIRPFLAGSKNMAAAGLPNGIFYDEGNGRGSWQQLRGGSNGQSSLIQFLDIVLGVEHTSEGNSTSHTSKNTPNHIKVSAFHEEVRNYMPGPHKRFLEHVSRMGSIREFAKLPVSTAEHKSLREAYEVAIKTMTEFRNKHLQIVARYIVLPSKRAYSGAKVDLASTSAVQDEQLTGTGGTALMPFLKQTRDETLKAGQLEREARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>E3R0R8</accession>
    <name>E3R0R8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_11855</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697479">
        <property type="protein sequence ID" value="EFQ36706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008100726.1">
        <property type="nucleotide sequence ID" value="XM_008102535.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3R0R8"/>
    <dbReference type="GeneID" id="24417218"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_11855"/>
    <dbReference type="HOGENOM" id="CLU_3142998_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ36706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="49" mass="5322" checksum="3580672C078D23C6" modified="2011-01-11" version="1">MMATADECTSCNDARETKRACRQAGGTMSGSTCHTERASDFLNKDEEFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q218</accession>
    <name>E3Q218_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Tat pathway signal sequence</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_00263</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Mycotoxin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ustYa family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089139.1">
        <property type="nucleotide sequence ID" value="XM_008090948.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q218"/>
    <dbReference type="STRING" id="645133.E3Q218"/>
    <dbReference type="GeneID" id="24405628"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00263"/>
    <dbReference type="eggNOG" id="ENOG502SQ6R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042941_0_2_1"/>
    <dbReference type="OrthoDB" id="3687641at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043386">
        <property type="term" value="P:mycotoxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365:SF4">
        <property type="entry name" value="CYCLOCHLOROTINE BIOSYNTHESIS PROTEIN O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365">
        <property type="entry name" value="YALI0B05434P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="63"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ25119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="291" mass="33217" checksum="01A9CEEFE86DE1A4" modified="2011-01-11" version="1">MSSEKVYRSVPYEEEEVESLAGSLNTESTDNVDAAATTSPTWKRMRLGDEHTCKEKARRLLRYWPWAAHGALLMTSIAFFAASFSLRYGNTQNTPDDTFFTEKYSSYSPASGIVKYHTERYNLTPVMDWSPFVGSGYQVDRAWDHITNNIGDQMVSHAELEKLGLDPKSIKITNPITGEEGYRAGLEVFHQLHCLNLLRMATYPDYYSRPDVGGDVATDTEDLRGHLDHCIEALRLNLMCQSDIGVFTFKMYPDLPVEGHWPDFSTLHTCRNFDDIRDWALTHSVTFEDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q286</accession>
    <name>E3Q286_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_00331</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ25187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089207.1">
        <property type="nucleotide sequence ID" value="XM_008091016.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q286"/>
    <dbReference type="GeneID" id="24405696"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00331"/>
    <dbReference type="HOGENOM" id="CLU_2120902_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ25187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="114" mass="13209" checksum="71C1B7CBA0AF816F" modified="2011-01-11" version="1">MSLNAIWKATEARCNEVHAIIIEFELLPRAYQVLDEDDHWLLAIALQKLVVERLYELRPKMEMVKLGLAVARDALLQGYVSEFDTEMSNMVARMKAHVVAWNGLKGEQLFRECY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q2W7</accession>
    <name>E3Q2W7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Pre-mRNA-splicing factor CWC21</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_00090</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWC21 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697331">
        <property type="protein sequence ID" value="EFQ24946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008088966.1">
        <property type="nucleotide sequence ID" value="XM_008090775.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q2W7"/>
    <dbReference type="STRING" id="645133.E3Q2W7"/>
    <dbReference type="GeneID" id="24405455"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00090"/>
    <dbReference type="eggNOG" id="KOG1869">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067891_2_1_1"/>
    <dbReference type="OrthoDB" id="10267305at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21372">
        <property type="entry name" value="cwf21_CWC21-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051372">
        <property type="entry name" value="CWC21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013170">
        <property type="entry name" value="mRNA_splic_Cwf21_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36562">
        <property type="entry name" value="SERINE/ARGININE REPETITIVE MATRIX 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36562:SF5">
        <property type="entry name" value="SERINE_ARGININE REPETITIVE MATRIX 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08312">
        <property type="entry name" value="cwf21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01115">
        <property type="entry name" value="cwf21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="CWF21" evidence="8">
        <location>
            <begin position="55"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="99"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="147"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="121"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ24946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="173" mass="20098" checksum="FE9E3B076997F04E" modified="2011-01-11" version="1">MSDNVGLSTPRGSGTSGYVQRNLAHMRPRDYGAPYPPKDADSLRHKQRQPDKEILEHDRKREVEVKVLDLRDTLEDEGLDEEEVEKRCDEMRTKLLAELEKQKNSRGGGAGPIRKHFKSHQVHEMADAKIKESERLRSALRISKDYEEGSHWKRQEERLRGSLEKEAQREDVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3T5</accession>
    <name>E3Q3T5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00831</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089707.1">
        <property type="nucleotide sequence ID" value="XM_008091516.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3T5"/>
    <dbReference type="STRING" id="645133.E3Q3T5"/>
    <dbReference type="GeneID" id="24406196"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00831"/>
    <dbReference type="eggNOG" id="KOG0575">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021323_1_0_1"/>
    <dbReference type="OrthoDB" id="346907at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359:SF1">
        <property type="entry name" value="INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE EPSILON SUBUNIT HOMOLOG 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SBK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="318"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ25687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="630" mass="70821" checksum="E8E3C5B751356DB9" modified="2011-01-11" version="1">MGDRRVRGSEEPSEEKTEPFSQTEIDARMRSIRVEEPFELTQADPVPLDRLRVEEHHHKQGIRILVRPLTRSRSVSPGNYNCQWLALRAEVASEQEPQHKVLAVSQTSRDIKFSVRIPPERLDDDTPRPPLWCELYYDPTSDNQILLNRSEVPISLTRISDGPASAASWSVNPGTPKALSPGTWRINVREIEVLDFRILEKRPAFFKQADAAGKEELTSSSNADALNASGKRSFAADDGEPRSEKKARTTQEAVTTRNDKEDGVIMFLRPAAEPLVFPLPTEAKSKEVVPTNGHALLDMQRDEAVVIPGGCEIDEYTVSKRDQIASTALSSVFTAEHSNVPDGIVTVKVLKTRSANNAGPKPQDNERNVIRQADMWLREYQSQDDLHHESIVKLYGGDARYLSLYMEHVDAKDLSAKGVWRSHVDHSFLGTRADAFAIMRDISGALHYLHDKHLVHNDIKPANILYSPARGAVLCDFGLSTHTSGPVTTGGTPYYIPPEFIGRKLRGPPSDVWALGVTMLYVLGKIPFPDARSRKGAKPALYWMIADVNRTPTQQQQQQQQQPHQQWGSAVDLMYVWLSEVALARDRLYPRDKLERLVSDMLIAVPSQRITMARVVRELYLMEQQALAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3T7</accession>
    <name>E3Q3T7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_00833</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089709.1">
        <property type="nucleotide sequence ID" value="XM_008091518.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3T7"/>
    <dbReference type="GeneID" id="24406198"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00833"/>
    <dbReference type="HOGENOM" id="CLU_3124934_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ25689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="50" mass="5418" checksum="37D9649970390A99" modified="2011-01-11" version="1">MGYLMKAVCRVSGLAKITSKAVYGDVFADASNLIDAAQEEHILTSSLSWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q3U9</accession>
    <name>E3Q3U9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_00845</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089721.1">
        <property type="nucleotide sequence ID" value="XM_008091530.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q3U9"/>
    <dbReference type="STRING" id="645133.E3Q3U9"/>
    <dbReference type="GeneID" id="24406210"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00845"/>
    <dbReference type="eggNOG" id="ENOG502SMA9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002341_5_0_1"/>
    <dbReference type="OrthoDB" id="443402at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF5">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="240"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ25701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="623" mass="71338" checksum="E29B26A01DC27D2E" modified="2011-01-11" version="1">MADPFTIIRTVSAILTFVEFAGKCVMTAKNLHQCGKTDDNARDENVVTKMQDLIDTVGLERAARPTSKAEDGLSEIIDECEVLGEEILKLLRKATKREGSEKSRRETLRATFSVVWNRRKVEDLQNKLQRSETGQKLEQILAMQSSHSNQVDSLHHYIKNLLSPTNQEGVLDNLSSLVGLFGSNDSILEQTNRQRILDALRVPEMRQRYDQLSDAAQGTFNWLIQSSKIPDHPELLVPLSTWLSDGKGIFHISGKPGSGKSTLMKLVAESRDAASLLDSWAGEEKFVKASVFIWKYGDAIQRTVNGVFPKYWEPRQHSPWLPMPDFHIAPKDVLEAFEHCIDPKGPAQHTHICLMLDGLDELNDPHELHTSFVQRLMRWRNDNPDKLKICVSSQEENAFMNKFPPQQRLRLHSITQGDIQQMVTTRLNLHPRFQTFSERDRRLFCSRIVEKSSGVFLWVKLVLDEIYEDLYQQRSFETPQATLSQVPEELEDYFSRIFSSIRKTDRKEASCLFLLASEFESMPALVFSFLEDILTLRMDDHQTDDHPMLWEDLELRHASFAARLRGHSRGLLEIVGAKRPGQQKENRSLSSLSSLACESSAMPMHQSIKDWLLYSPPETFKAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q485</accession>
    <name>E3Q485_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycosyltransferase family 28 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_00541</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089417.1">
        <property type="nucleotide sequence ID" value="XM_008091226.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3Q485"/>
    <dbReference type="GeneID" id="24405906"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00541"/>
    <dbReference type="eggNOG" id="KOG1192">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000537_1_0_1"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016906">
        <property type="term" value="F:sterol 3-beta-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000100">
        <property type="entry name" value="Glycosyltransferase family 1 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000009">
        <property type="entry name" value="Sterol 3-beta-glucosyltransferase UGT80A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010610">
        <property type="entry name" value="EryCIII-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050426">
        <property type="entry name" value="Glycosyltransferase_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050:SF13">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE UGT80A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06722">
        <property type="entry name" value="EryCIII-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00726">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyltransferase family 28 N-terminal" evidence="3">
        <location>
            <begin position="142"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="Erythromycin biosynthesis protein CIII-like C-terminal" evidence="4">
        <location>
            <begin position="475"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="111"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="683"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="773"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="992"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1039"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1162"/>
            <end position="1250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1268"/>
            <end position="1308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="711"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="738"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="775"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1053"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1171"/>
            <end position="1185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1200"/>
            <end position="1214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1222"/>
            <end position="1238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1286"/>
            <end position="1295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ25397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1308" mass="141693" checksum="DCA74ADF0EC24379" modified="2011-01-11" version="1">MTGVHKIEAGASSSAPPPPSRHSDMNLDVTDSQEVPDALVSDGFSLPSLETDNQAPPAYGDLPNQLQFSQAGFEAGANVTGDGRVNININQSGNRLAEILAPTLRSQLLADKRPQGPLPPAYTPPSLGGQPGQTPPPQLNLVIQIVGSRGDVQPFVALGKVLKDTYGHRVRIATHATFQKFVEENGLEFFCIGGDPAELMAFMVKNPGLMPGFDTLKSGEVSKRRRGIQEILLGCWRSCIEAGDGLGPPPKPHARNQPLDENYGIPGDPNHKPFVADAIIANPPSFAHIHIAEKMGIPLHLMFTMPWTPTRAFPHPLANIQSTNTDAVMTNYVSYALVEMMTWQGLGDVINRFREKALDLEPMSLIWAPGVLTRLRIPYTYCWSPALIPKPNDWGREIDISGFYFLNLASAFTPEPELAAFLAAGPPPVYIGFGSIVVDDPNALTRTIFDAVHRTGVRALVSKGWGGLGAEDVGLPPSVFMLGNVPHDWLFKHVSAVCHHGGAGTTAAGIQAGKPTIIVPFFGDQPFWGAMVSKAGAGPDPIPYKELSGDKLAEAINFAIRPETQARAQELGQKIREEKGTDLGGKSFHDHLNTDELRCSIEPSRAAAWRVRRTKVKLSPMAAAVLVDNGLIKYSDLKLYRPKEYITEGQPWDPVSAVATSLVADLSNIGMAVADFPRELFKARSKGDKTPDPPTTPSLPGGAPGKKPFQGSDSGSLAPSTRASESSTQLGLIEAGGSTPTLPLSPQPDTESLAQSYKTSAAPSMVFSPVETASIAPSETAPSENLSTAQPGRPPNSPGKRSFSESSPVAVDAAVAAGTSVSRIVTTGVKTPMNVCLGLARGFRNAPRLYNDDTVRPPEKVTDFSSGVKVAAKEFGYGMFDGIGGLVTQPLKGAEKEGVPGLIKGFGKGIGGLIFKPASAVWSVPAYTMQGVHATLRNAFSTSVQNYIIASRMKQGQMDMEAAGIAEREDVIARWNSVKFDLKNFQAMKIKEQREKQRTDGGPYIQSQPEKSLTPPVTGWSHTRKLTFEERKQLHARKEAWKKGHVEAIVPPSRSDSSFAESSTASVVEDEEFERAIRASVAETSRGNSQEDAAVEQAIRASINHFRSSGTGIPDVVPEKPMSFDRDAKHWDQDPFSSAELQITDEEYQRLVEQAIQQSMSLQAAGVHPEQGSHGDDKEFRRALEQSRIAQHSGHEEDEELKRILEESKRHETEGTADDEEELRRAIEASEAEHREQLSKAAAAKSEEEVVMEYVKKQSLAEEEYRRNALKGKARKVADDEDDDEDLKRAMEESLKLSGRSGQSSSFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4H3</accession>
    <name>E3Q4H3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Tyrosine--tRNA ligase</fullName>
            <ecNumber evidence="10">6.1.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Tyrosyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_00629</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>tRNA(Tyr) + L-tyrosine + ATP = L-tyrosyl-tRNA(Tyr) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10220"/>
            <dbReference type="Rhea" id="RHEA-COMP:9706"/>
            <dbReference type="Rhea" id="RHEA-COMP:9707"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78536"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.1" evidence="10"/>
    <dbReference type="EMBL" id="GG697332">
        <property type="protein sequence ID" value="EFQ25485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089505.1">
        <property type="nucleotide sequence ID" value="XM_008091314.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4H3"/>
    <dbReference type="STRING" id="645133.E3Q4H3"/>
    <dbReference type="GeneID" id="24405994"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_00629"/>
    <dbReference type="eggNOG" id="KOG2623">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024003_4_0_1"/>
    <dbReference type="OrthoDB" id="337870at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004831">
        <property type="term" value="F:tyrosine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006437">
        <property type="term" value="P:tyrosyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00805">
        <property type="entry name" value="TyrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.240.10:FF:000001">
        <property type="entry name" value="Tyrosine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000227">
        <property type="entry name" value="Tyrosine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="entry name" value="RNA-binding S4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.240.10">
        <property type="entry name" value="Tyrosyl-Transfer RNA Synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002307">
        <property type="entry name" value="Tyr-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024088">
        <property type="entry name" value="Tyr-tRNA-ligase_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032005">
        <property type="entry name" value="TyrRSs_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00234">
        <property type="entry name" value="tyrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11766:SF0">
        <property type="entry name" value="TYROSINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11766">
        <property type="entry name" value="TYROSYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16714">
        <property type="entry name" value="TyrRSs_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01040">
        <property type="entry name" value="TRNASYNTHTYR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10 13" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosyl-tRNA synthetase C-terminal" evidence="12">
        <location>
            <begin position="448"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="613"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="618"/>
            <end position="636"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF16714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ25485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="636" mass="71876" checksum="6265438776A4A79E" modified="2011-01-11" version="1">MSSTLASRLPELRRNICRRCAEIPVIQLQPNRPRWISQKVVEKRRMGEEEWAKRAEAIEQGELQNIWDIFEERGYVKDVAGRTPQIKELLRTKRIGAYVGVDPTAASLHVGHLLPFMPLFWMHLHGYTAVSLVGGATGRIGDPTDRLKTREVMANSEVSMNITKIHYQLKKIWSNVEALGRKYGKEPEWAGKKHLVNNNMWWQGLPLYDVMKRLGRYMRIGPMLSRDTVKNKMEKGDGMSLAEFIYPLMQGWDFWHLYSKLGVQMQIGGSDQFGNIVTGIEAVKTIRSSEENPNMRMPDTWKDDPIGFTVPLLTDNAGTKFGKSAGNAVWLDPFMTSAFDLYGYFARRPDNEVEKLLKLFTFLPTTSIEKLMIEHAQDPPKRVAQHTLAFEVLSLVHGADVAIREQQQHQFMFSKGGNAAQIAGATGASEEGQDFLAPYKAIEGHPTTLNNAPKMDMQLPENLIYNQGIARILYAAGLASSVSEGHRIARAQGAYVAAAPGKDMRGLVPGNLDWTPVKLWYPQDVPKFLIDGRLLIIRKGKHNVRIIEVVSDEEWQESGKAYPGEPYKGKTRVLMQQLKEMAAAEGRKLSRRELEQMLKEKLAADEEEVTVANNPDIKFPKKSERQQAFGEGHKLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q4Y0</accession>
    <name>E3Q4Y0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_01289</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ26145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090165.1">
        <property type="nucleotide sequence ID" value="XM_008091974.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q4Y0"/>
    <dbReference type="STRING" id="645133.E3Q4Y0"/>
    <dbReference type="GeneID" id="24406654"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01289"/>
    <dbReference type="eggNOG" id="KOG3234">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_7_1_1"/>
    <dbReference type="OrthoDB" id="10264728at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031416">
        <property type="term" value="C:NatB complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004596">
        <property type="term" value="F:protein-N-terminal amino-acid acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000058">
        <property type="entry name" value="N-acetyltransferase (Nat5)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051646">
        <property type="entry name" value="NatB_acetyltransferase_subunit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45910">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45910:SF1">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="4">
        <location>
            <begin position="2"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="153"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ26145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="190" mass="22146" checksum="26D1DA4B9D50830F" modified="2011-01-11" version="1">MATFRRFRPEDVNKFSKCNLDPLTETYELAFYLQYHAKWPSMFQVCEDMSGNIIGYIMGKLESSPDVYKFSEHYLPWHAHITALTVAPEARRLGIGKILSEQLEAAADANDAWFVDLFVRTSNHKAITFYKSMGYSVFRVVKDYYGDHATDPTRDSEDAYDMRKPMKRDTKLQHIRDDGEKHEVDPSDVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5B0</accession>
    <name>E3Q5B0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Fatty acid hydroxylase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_01021</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089897.1">
        <property type="nucleotide sequence ID" value="XM_008091706.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5B0"/>
    <dbReference type="STRING" id="645133.E3Q5B0"/>
    <dbReference type="GeneID" id="24406386"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01021"/>
    <dbReference type="eggNOG" id="KOG0873">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047036_5_0_1"/>
    <dbReference type="OrthoDB" id="1658724at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050307">
        <property type="entry name" value="Sterol_Desaturase_Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11863">
        <property type="entry name" value="STEROL DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="5">
        <location>
            <begin position="146"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ25877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="304" mass="36125" checksum="E9F305528757B0CC" modified="2011-01-11" version="1">MASWNSTVVFPNHTSTQDYFGVLDDVSKYNVQLNILERLWAAWYVWMQNDILATGIMTFVMHEVVYFGRSLPWIIIDAIPYFRRWKIQKQKIPTWKEQFECGALVLFSHFTVELPQIWLFHPIATWCGLDYGVPFPPWWKTAYQIAIFFVLEDTWHYWVHRGAHWPPIYKAVHKLHHYYSAPFGMTAEYASPIEVMFLGLGTIGSPVLWVLITKELHLFTMYLWIILRLFQAIDSHSGYDFPWSLRHVLPFWAGAEHHDVHHEKFIGNYASSFRWWDYIMDTEAGAEAHQRRREKRLAKAKKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5C8</accession>
    <name>E3Q5C8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_01039</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089915.1">
        <property type="nucleotide sequence ID" value="XM_008091724.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5C8"/>
    <dbReference type="GeneID" id="24406404"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01039"/>
    <dbReference type="HOGENOM" id="CLU_2793848_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ25895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="68" mass="7729" checksum="8D9F7AAEED38FDAB" modified="2011-01-11" version="1">MPEETPSEVYDSLDDSVSTQSITSRLLVSSWTVRIKPFPGWGPNEDVKGQSPKPEWGKRTKYDTWSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5H3</accession>
    <name>E3Q5H3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Endoribonuclease L-PSP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_01084</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697333">
        <property type="protein sequence ID" value="EFQ25940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008089960.1">
        <property type="nucleotide sequence ID" value="XM_008091769.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5H3"/>
    <dbReference type="STRING" id="645133.E3Q5H3"/>
    <dbReference type="GeneID" id="24406449"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01084"/>
    <dbReference type="eggNOG" id="ENOG502T48I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139331_0_0_1"/>
    <dbReference type="OrthoDB" id="309640at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00448">
        <property type="entry name" value="YjgF_YER057c_UK114_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="entry name" value="RutC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="YjgF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ25940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="115" mass="12954" checksum="D4D0666F3F6B0711" modified="2011-01-11" version="1">MSKAGNTLYIAGMRGIDSSNDTLSPVGIERIRKAYANMIQLAELAGTDRFSAVRLVVYTTDMYRYRPLCNRAQTEFWGEDPNRHPPRSIIEVQRLNDDDIVEVEGTFLVPSTQGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q5N9</accession>
    <name>E3Q5N9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">chitinase</fullName>
            <ecNumber evidence="3">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">GLRG_01674</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Dual chitinase/transglycosylase that plays a role in cell wall architecture. Chitinase and transglycosylase activities are coupled. Required for the polysaccharide cross-linking at the septa and the cell wall. More specifically, transfers chitin to 1,6-beta-glucan in the cell wall.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the glycosyl hydrolase 16 family. CRH1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="3"/>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090550.1">
        <property type="nucleotide sequence ID" value="XM_008092359.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q5N9"/>
    <dbReference type="STRING" id="645133.E3Q5N9"/>
    <dbReference type="GeneID" id="24407039"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01674"/>
    <dbReference type="eggNOG" id="ENOG502QQ71">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027506_3_0_1"/>
    <dbReference type="OrthoDB" id="4781at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02183">
        <property type="entry name" value="GH16_fungal_CRH1_transglycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.200:FF:000152">
        <property type="entry name" value="Cell wall glucanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF68">
        <property type="entry name" value="GLYCOSIDASE CRH1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179443" description="chitinase" evidence="14">
        <location>
            <begin position="20"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="15">
        <location>
            <begin position="15"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00038074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00093308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EFQ26530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="367" mass="38661" checksum="FA1E6E044CC65C72" modified="2011-01-11" version="1">MLFPRRLLAAAALATTASAQTYSSCNPLHQTTCPADTALGMAIHVDFTQGAVNSFAASGNPTYGSDGVTFTVAASGQAPQLMSLFYIMFGRVEITLKAATGAGIVSSLVLQSDTLDEIDLEWLGADPTEVQSNYFGKGDVTTYNRGQFHQTDNNQDKFMKYTIDWTSERIVFSVDGTIVRTLTEAEADENQYPQTPMQVKFGAWSGGDPANAPGTIDWARGPTDFSKGPFHMVVKDISITDYSTGKEYKYTGTSGNWDSIQAVGGQINGNLGKARQVTYTATAAADTGSPAPTVPRGGIGADESATATQTGWPWVASARPTGGSVPDGWRMNSEGKIIPDGAGTSVRPQCLAVLASLVLGAVAVLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q6H3</accession>
    <name>E3Q6H3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_01565</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697334">
        <property type="protein sequence ID" value="EFQ26421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090441.1">
        <property type="nucleotide sequence ID" value="XM_008092250.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q6H3"/>
    <dbReference type="GeneID" id="24406930"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01565"/>
    <dbReference type="HOGENOM" id="CLU_2605889_0_0_1"/>
    <dbReference type="OrthoDB" id="5132745at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ26421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="79" mass="8372" checksum="E0D154FC2548AAC2" modified="2011-01-11" version="1">MSGAEGTHANTGGFDLLKRATQAMMSGSSHTRSPIRQTEPLWPMASSLNILNICLVKASALARLSPLSGPRCVTPYPFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q712</accession>
    <name>E3Q712_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Acyl-CoA thioesterase II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_02470</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the C/M/P thioester hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697335">
        <property type="protein sequence ID" value="EFQ26650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008090670.1">
        <property type="nucleotide sequence ID" value="XM_008092479.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q712"/>
    <dbReference type="STRING" id="645133.E3Q712"/>
    <dbReference type="GeneID" id="24407835"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02470"/>
    <dbReference type="eggNOG" id="KOG3016">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032690_3_0_1"/>
    <dbReference type="OrthoDB" id="68328at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005782">
        <property type="term" value="C:peroxisomal matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047617">
        <property type="term" value="F:fatty acyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006637">
        <property type="term" value="P:acyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009062">
        <property type="term" value="P:fatty acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03444">
        <property type="entry name" value="Thioesterase_II_repeat1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03445">
        <property type="entry name" value="Thioesterase_II_repeat2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.129.10:FF:000074">
        <property type="entry name" value="Acyl-CoA thioesterase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.210">
        <property type="entry name" value="Acyl-CoA thioesterase, double hotdog domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049450">
        <property type="entry name" value="ACOT8-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042171">
        <property type="entry name" value="Acyl-CoA_hotdog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003703">
        <property type="entry name" value="Acyl_CoA_thio"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049449">
        <property type="entry name" value="TesB_ACOT8-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11066">
        <property type="entry name" value="ACYL-COA THIOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11066:SF34">
        <property type="entry name" value="ACYL-COENZYME A THIOESTERASE 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13622">
        <property type="entry name" value="4HBT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20789">
        <property type="entry name" value="4HBT_3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA thioesterase-like N-terminal HotDog" evidence="3">
        <location>
            <begin position="43"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA thioesterase-like C-terminal" evidence="4">
        <location>
            <begin position="148"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ26650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="352" mass="39625" checksum="5328F663E9A5523E" modified="2011-01-11" version="1">MASGRSTIIRPPPDDPNKAPIENVLEVTELGVLGPDIFTNTRQPWHPPGARGIFGGAVIAQCLASAQKTVPNDFFVHSCHCYFLLAGSSEIPILFHVERVRDGRSFATRTVQARQRGRCIFTTTVSFVKEGSGGEKQVRHAAPLPEGVAPPPADWNDEPEWNQHSPFQTHRITLVGANDEGKRLDEIKSRNWVRARGRISVSGGHQAHLNALAYMSDSYFIGTVGRIHKLWRFPFRPDEFPDLPPELREQVERLNEFEGNAAPGGIEYWKTRPHLGMMVSLDHSIYFHEPRRLRADEWMFTEMESPWSGEGRGVVLQKIFSADGTLLATCVQEGLIRLKQEEDEEKETKSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7X1</accession>
    <name>E3Q7X1_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphatidate phosphatase APP1 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_02154</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ26983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091003.1">
        <property type="nucleotide sequence ID" value="XM_008092812.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7X1"/>
    <dbReference type="STRING" id="645133.E3Q7X1"/>
    <dbReference type="GeneID" id="24407519"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02154"/>
    <dbReference type="eggNOG" id="ENOG502QT5E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008292_0_0_1"/>
    <dbReference type="OrthoDB" id="2117591at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008195">
        <property type="term" value="F:phosphatidate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017210">
        <property type="entry name" value="APP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019236">
        <property type="entry name" value="APP1_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052935">
        <property type="entry name" value="Mg2+_PAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28208">
        <property type="entry name" value="PHOSPHATIDATE PHOSPHATASE APP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28208:SF3">
        <property type="entry name" value="PHOSPHATIDATE PHOSPHATASE APP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09949">
        <property type="entry name" value="APP1_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037464">
        <property type="entry name" value="UCP037464_APP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphatidate phosphatase APP1 catalytic" evidence="2">
        <location>
            <begin position="386"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="545"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="611"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="857"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="550"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="645"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="684"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="728"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="755"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="794"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="857"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="877"/>
            <end position="899"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ26983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="899" mass="98431" checksum="79893EBADE10D37A" modified="2011-01-11" version="1">MPTFSDYTNYGGGGAGRSATGAGTADGAGAGNGYGAPSTDDLPTPGERGFRRKWLAAKAGSVYRAGATAVNEIREGYAQTRIRPLEPEDGMPRTTIPGSFPNVAITVRGDDQMVIFPSYAKRHVKRDWTAEYQQHSEEQPGSARDQEFWRKEWERNEDEKAIVDIDVRGWVYSPHKGPITRRNRILIGLARQLSGIPAPRQDAPAPADNLSALHQSHEERREQEKIAKEAAEIEKRGQEERRVATRGGFSEAPKDASDDDADSIYRARSRSRSGAHTPMTAPGSPKLAPSRQNTTGTDLTDAELSVANANLMARIAPFMTTPLIQLPITVFFYNDEKSASRTVQTNDAGHFILRAALEFVPTHVRILANENLSATQEVKIIEPKGVSLISDIDDTIKRSNISGGAKEIFRNTFVRELKDLTVEGVREWYNELHKMGVSMHYCSNSPWQLFPVLASYFMIAGLPPGSLHLKQYSGMLQGIFEPVAERKKSTLTRLMHDFPERRFLLVGDSGEADLEVYTELVEAHPGRIIAIFIRDVTTPEQAGYFDNSFEGGSSRQKAPTLKITHQSDTPSSRPGLPPRGEAKTVGPVMGDLIDLSDEPEEITLSNTAALAQVKARPKPRSSSTDLVVGRKPAPPLPNKPVALRSTPSDTSVNTLGVNGGAAPPPVPRSRKPSADRSGPHPLSQMHNSSQQTVGSSSGLPNAAKIPAATNRTAKVPPPPPPPRRRDAPSSSRSLSPRGKTNGRRLSSNSDIDFDALPPSAASQPQATLPTFTRTRTGSLRSGSTSPIGSPSLGPAAPAAATAPPNRKHELWMRRLQRAQEILESHGVALYTWRRGDDVVTEAIGLVREELKKVGLNGERDAKTEGKRFERQIRREQSQQQHQQQQRPQQQQQGSYQQRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q7X6</accession>
    <name>E3Q7X6_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Amidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_02159</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ26988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091008.1">
        <property type="nucleotide sequence ID" value="XM_008092817.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q7X6"/>
    <dbReference type="STRING" id="645133.E3Q7X6"/>
    <dbReference type="GeneID" id="24407524"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02159"/>
    <dbReference type="eggNOG" id="KOG1211">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020129_1_0_1"/>
    <dbReference type="OrthoDB" id="5423360at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46310">
        <property type="entry name" value="AMIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46310:SF7">
        <property type="entry name" value="AMIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012249025" description="Amidase domain-containing protein" evidence="1">
        <location>
            <begin position="16"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="domain" description="Amidase" evidence="2">
        <location>
            <begin position="195"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ26988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="648" mass="68735" checksum="C5D7E213E0E2DEB4" modified="2011-01-11" version="1">MKVFALLALVGLAVADLIQTGASLKLDDVHYFVSPFSQGKPSNRSVNVKSLPRAFGFTPVTIVSDPVREDGLVSLFSNWTAKDDVWQPAFLSVIFLAGAESPLMTKTSYEGSNKTQSVVIPLSAGRSIPSGPYFLDTYTGNVYQAFRLYDDFAGAFSESLLQTPDGTFQTLSAQVPSTASLTIGVPSRLYFTPTAEKPLAGVRVGVKDIYALAGVRGSNGNRAWYSLYPPARATGPAIQNLIDAGAIIVGYQKPSQFANGEMATADWVDYHAPFNPRGDGYNDPSSSSSGAGASVASYDWLDIAVGSDTGGSIRGPAGVQGLFGNRPSHDLVSLEGVMPLSPVLDTAGFLTRNPYLWDEANKALYRGNYTSLAGVEVKYPKTLYTLGLPKLDSIPPAQVPAARMLNKFASDLAGFLGTNVTTFNLTSSWASSAPAEVRNQTLTDVLGLTYATLITKQQTALVRDPFYADYAATHDGRLPFVNPVPLARWAWGDAQPATALAEAKANKTLFADWFNTRVLPPASDDASSTCSSGLLLYVGSAGIANPRNQYPSSAPRPPVGFSSGRLSVFSGAPDHVFPLGEVGSVSIVTNHTEVLPVTVDVMAARGCDGLLVRLAQDLLAAGLLKVPKAGGTLTGGEVLMRRDVHDWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q841</accession>
    <name>E3Q841_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DnaJ domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_02224</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697336">
        <property type="protein sequence ID" value="EFQ27053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091073.1">
        <property type="nucleotide sequence ID" value="XM_008092882.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q841"/>
    <dbReference type="STRING" id="645133.E3Q841"/>
    <dbReference type="GeneID" id="24407589"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02224"/>
    <dbReference type="eggNOG" id="KOG0691">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1012655_0_0_1"/>
    <dbReference type="OrthoDB" id="376357at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000390">
        <property type="term" value="P:spliceosomal complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052094">
        <property type="entry name" value="Pre-mRNA-splicing_ERAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44313">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44313:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="7">
        <location>
            <begin position="20"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="135"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="135"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="185"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="200"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ27053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="274" mass="31440" checksum="3C41725959160868" modified="2011-01-11" version="1">MDTNKDLLAKAQEYSSNNVDLYELLQISTTITEEKEVRRAWRKQSLNYHPDKLKDAFDPEKWELIETARDILLDAAARAAYDNARKAALLRKAERDRVQGQRKRLIDELEAAEQEGKRQKLADEERARELERERARLAEEGRRRMAEEAERFKKETLERLEREREPDEYDEKLAELQRRLDEKKRLKAEKKARKKGGVADGADPAAASGTSNTPDPVPAPAPKAPVKWEDLKARMSAAQRLKEVKKAAEAGLATEEDVKQKYEALRALNPNRAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q975</accession>
    <name>E3Q975_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">DNA damage-binding protein CMR1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_01749</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">DNA-binding protein that binds to both single- and double-stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the WD repeat DDB2/WDR76 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091274.1">
        <property type="nucleotide sequence ID" value="XM_008093083.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q975"/>
    <dbReference type="STRING" id="645133.E3Q975"/>
    <dbReference type="GeneID" id="24407114"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01749"/>
    <dbReference type="eggNOG" id="KOG4328">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017019_1_1_1"/>
    <dbReference type="OrthoDB" id="9890280at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
        <property type="term" value="C:nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000001">
        <property type="term" value="P:regulation of DNA damage checkpoint"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000562">
        <property type="entry name" value="DNA damage-binding protein CMR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050853">
        <property type="entry name" value="WD_repeat_DNA-damage-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14773">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14773:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 8 9" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="350"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="35"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFQ27254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="516" mass="57433" checksum="B26F493CBD918A87" modified="2011-01-11" version="1">MPIKKKEEPEEAISAFERMRRENIARNQSILKDLAHTSNKIMPAKPKPAPKPRSAPVKREAAAAPTGPVRRSARVAGLDADNETLKRKYEVEIEDQAAKEKAKRKRVGGTLSLGDIAVEGKKFNKGIDGLRSLVPRGAQPGVPTFTDEDIENTSDKDLKELRRKMGKLELYDKWIPNDIKICPQRIYASTFHPTEEKALIFAGDKEGALGVFDASQDGPPESNDDDDGQEVEWKEPEIGAYKIHSRTITTIIVSPYDHQKVLTSSYDSTIRVLDLAKDMCVPVWEPADKEEDVPLSAIDVPLTDKDLIYFSTLGGAVGKVDTRDPKGFETWQLSDNKIGGFSLNPREPHLLATASLDRTVKIWDLRNIKGKGDMRFPAMLYEHDSRLSVSHASWSPGGHIATSSYDDTIKIYDWADRAAWDSSDGMEPKEVIEHNNQTGRWVTILKPQWHRRPRDGIQKFVIGNMNRFVDVYAANGEQLAQLGGDGISAVPAVAQFHPTMDWVAGGTASGKLCLWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9H3</accession>
    <name>E3Q9H3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_01847</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091372.1">
        <property type="nucleotide sequence ID" value="XM_008093181.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9H3"/>
    <dbReference type="STRING" id="645133.E3Q9H3"/>
    <dbReference type="GeneID" id="24407212"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01847"/>
    <dbReference type="eggNOG" id="KOG1211">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009600_0_0_1"/>
    <dbReference type="OrthoDB" id="6428749at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42678">
        <property type="entry name" value="AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42678:SF2">
        <property type="entry name" value="AMIDASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G14410)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="2">
        <location>
            <begin position="28"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ27352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="440" mass="47160" checksum="F7BAF65F01D2B075" modified="2011-01-11" version="1">MSTEPYRLSATEASAKIRAGDLTVEEYARSLLSRIEQRDPVVKAWEYINPDQVIARAKELDAIPPEKRGPLHGVAVAVKDIIYTKDMPTQHGSPIYAGDAPKVDAGSIIVLRQAGALFLGKTTTTEFAGTVRGPKTVNPHDTSRTPGGSSSGSGAAVGDFQAPIALGTQTGGSTIRPGSFNGIYALKPTWNSISREGQKIYSLILDTLGFFARSVEDLQLMADVFDLQDDEAPKPEFSVKGAKFALIKTMVWPQAGPGTQSAIAKATELLRKHGADVEEVEFAPELQDLPAWHGTVLHSDGRPTFLPEYRVAKDLLDEFLVSHVDNTNKISRAAQLEAFDNIAMARPKVDKMLGKYDAVLVPSVVDEAPVGTASTGSAAFNGLWTALHVPVVNIPGFKGPNGMPVGVSLVAPRYHDRHLLTVSKAVGEIFEAEGGWKSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9I3</accession>
    <name>E3Q9I3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11 12">Endo-1,4-beta-xylanase</fullName>
            <ecNumber evidence="4 11 12">3.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">GLRG_01857</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11 12">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-xylosidic linkages in xylans.</text>
            <dbReference type="EC" id="3.2.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11 12">Glycan degradation; xylan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11 12">Belongs to the glycosyl hydrolase 11 (cellulase G) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.8" evidence="4 11 12"/>
    <dbReference type="EMBL" id="GG697337">
        <property type="protein sequence ID" value="EFQ27362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091382.1">
        <property type="nucleotide sequence ID" value="XM_008093191.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9I3"/>
    <dbReference type="SMR" id="E3Q9I3"/>
    <dbReference type="GeneID" id="24407222"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_01857"/>
    <dbReference type="eggNOG" id="ENOG502RXA7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052631_0_1_1"/>
    <dbReference type="OrthoDB" id="2115822at2759"/>
    <dbReference type="UniPathway" id="UPA00114"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031176">
        <property type="term" value="F:endo-1,4-beta-xylanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.180:FF:000001">
        <property type="entry name" value="Endo-1,4-beta-xylanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013319">
        <property type="entry name" value="GH11/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018208">
        <property type="entry name" value="GH11_AS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033119">
        <property type="entry name" value="GH11_AS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033123">
        <property type="entry name" value="GH11_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001137">
        <property type="entry name" value="Glyco_hydro_11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46828:SF3">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46828">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00457">
        <property type="entry name" value="Glyco_hydro_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00911">
        <property type="entry name" value="GLHYDRLASE11"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00562">
        <property type="entry name" value="CBM1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00776">
        <property type="entry name" value="GH11_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00777">
        <property type="entry name" value="GH11_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51761">
        <property type="entry name" value="GH11_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11 12" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9 11 12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 11 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 11 12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0732">Signal</keyword>
    <keyword evidence="5 11 12" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179555" description="Endo-1,4-beta-xylanase" evidence="14">
        <location>
            <begin position="20"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="GH11" evidence="16">
        <location>
            <begin position="28"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="15">
        <location>
            <begin position="247"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="213"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="221"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="11">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EFQ27362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="283" mass="29396" checksum="4B9AAF36A7E4FFE1" modified="2011-01-11" version="1">MVSFTSVFVALTAFAGALAAPGELMKRQSTPSSTGTHNGFYYSWWTDGGSPVTYTNGPGGQYSVVWQSGGNFVGGKGWNPGSARTITYSGTYQPNGNSYLAIYGWTRSPLIEYYIVENFGTYNPSSGATKKGSVVSDGSTYDIYVSTRTNAPSIDGTRTFQQYWSVRQNKRVGGSVNTATHFNAWAQVGLNLGTHDYQIVATEGYFSSGSATITVGSSGSSPPPNTPPTTPPSTPPSGGGGGGSGGSCAAKWGQCGGSGWTGATCCVSGSTCSAQNQWYSQCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3Q9Y3</accession>
    <name>E3Q9Y3_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DASH complex subunit DAD4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Outer kinetochore protein DAD4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">GLRG_02815</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
            <location evidence="3">Centromere</location>
            <location evidence="3">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DASH complex DAD4 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091691.1">
        <property type="nucleotide sequence ID" value="XM_008093500.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3Q9Y3"/>
    <dbReference type="STRING" id="645133.E3Q9Y3"/>
    <dbReference type="GeneID" id="24408180"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02815"/>
    <dbReference type="eggNOG" id="ENOG502S890">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_177920_1_1_1"/>
    <dbReference type="OrthoDB" id="5516652at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042729">
        <property type="term" value="C:DASH complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008608">
        <property type="term" value="P:attachment of spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013959">
        <property type="entry name" value="DASH_Dad4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28222">
        <property type="entry name" value="DASH COMPLEX SUBUNIT DAD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28222:SF1">
        <property type="entry name" value="DASH COMPLEX SUBUNIT DAD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08650">
        <property type="entry name" value="DASH_Dad4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8" id="KW-0132">Cell division</keyword>
    <keyword evidence="15" id="KW-0137">Centromere</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="9" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-0498">Mitosis</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="17">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00030569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EFQ27671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="71" mass="8197" checksum="EAC984123F7BF67D" modified="2011-01-11" version="1" fragment="single">ESPHEHQQNLLLSRIITNVEKLNEAVVVMNRALQEINIQNMNVELVAQMFKNYQSNVLFHLEATDNLKPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QA49</accession>
    <name>E3QA49_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bystin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_02881</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bystin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091757.1">
        <property type="nucleotide sequence ID" value="XM_008093566.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QA49"/>
    <dbReference type="STRING" id="645133.E3QA49"/>
    <dbReference type="GeneID" id="24408246"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02881"/>
    <dbReference type="eggNOG" id="KOG3871">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029727_0_1_1"/>
    <dbReference type="OrthoDB" id="2192561at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007955">
        <property type="entry name" value="Bystin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12821">
        <property type="entry name" value="BYSTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12821:SF0">
        <property type="entry name" value="BYSTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05291">
        <property type="entry name" value="Bystin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ27737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="489" mass="54010" checksum="9B9583B14B70E322" modified="2011-01-11" version="1">MGKATTPTDRQARRHNPLQDDILATGPLKNKAPKQKKKGKGTQDDDDHGEGFVDATRSRTILRLGRELAEEDGPAKPAAAAKPTVDLFGIESRYGVDVGDEQAYEDEEAWGEEDEIVEEIEIDPEDLETYRKFLPEAEDDPAAMLNQHGWGSKGPDDEMAGGGTNLTELILEKIAAHEAAEARKAAGVPAVDEDYQLPPKVIEVYTKVGYILSRYKSGPLPKPFKVLPTLPHWEDIIQITEPQKWTPNAVYQATRIFSSSKPLVCQKFMEIVVLDKVREDIYENKKLNVHLFNALKKSLYKPRAFFLGFLFPLLSSGCTIREAHIVSAVLARVSVPVLHSAAALKGITEIAAQEASQGTEGGGAANIFIKTLLEKKYALPYQVIDSVVFHFLRFRSVDPASIKEGQSVSGDMVKSLPVVFHQSLLAFAQRYRNDLSEDQREALLDLLLTHGHHSIAPEIRRELLAGRGKGVAVEEQAAPFDGDDTMLVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAD7</accession>
    <name>E3QAD7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PCI domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_02969</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CSN7/EIF3M family. CSN7 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697338">
        <property type="protein sequence ID" value="EFQ27825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091845.1">
        <property type="nucleotide sequence ID" value="XM_008093654.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAD7"/>
    <dbReference type="STRING" id="645133.E3QAD7"/>
    <dbReference type="GeneID" id="24408334"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_02969"/>
    <dbReference type="eggNOG" id="KOG3250">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054426_0_0_1"/>
    <dbReference type="OrthoDB" id="10265275at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008180">
        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045237">
        <property type="entry name" value="COPS7/eIF3m"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15350:SF5">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15350">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 7/DENDRITIC CELL PROTEIN GA17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22061">
        <property type="entry name" value="CSN7_HB_subdom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0736">Signalosome</keyword>
    <feature type="domain" description="PCI" evidence="4">
        <location>
            <begin position="2"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="219"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="238"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="254"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="274"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ27825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="299" mass="32569" checksum="82E42BA95916701B" modified="2011-01-11" version="1">MEQTKALNALEPFLALSKSATSPRAAADLITRATSNPNTFLFTELLEAPQIQALSQSPEFLPHLRLLEIFSYGTYTTYLSSGQQLPQLNDAQTLKLRQLSLLTLSSNRSNLSYAALQSALGLPSARALEDLVISAIYAGLIDATLDPRRQVVQVNSLAALRDLAPGAVPPMIRALHAWSSRCESTLEDLEAQIVGIRDAAARRQRDKADQEARLAKLVDEVRKDPEAGTGTGRKLAVGHGGGGERGSGFLGHTSRAQRYNKRGSTSMMDNTAESIDDEAMDVDEEDPEQEKKRASRRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>E3QAS4</accession>
    <name>E3QAS4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">glycogenin glucosyltransferase</fullName>
            <ecNumber evidence="10">2.4.1.186</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_03106</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Self-glucosylating initiator of glycogen synthesis. It catalyzes the formation of a short alpha (1,4)-glucosyl chain covalently attached via a glucose 1-O-tyrosyl linkage to internal tyrosine residues and these chains act as primers for the elongation reaction catalyzed by glycogen synthase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-tyrosyl-[glycogenin] + UDP-alpha-D-glucose = alpha-D-glucosyl-L-tyrosyl-[glycogenin] + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23360"/>
            <dbReference type="Rhea" id="RHEA-COMP:14604"/>
            <dbReference type="Rhea" id="RHEA-COMP:14605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:140573"/>
            <dbReference type="EC" id="2.4.1.186"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>[1,4-alpha-D-glucosyl](n)-L-tyrosyl-[glycogenin] + UDP-alpha-D-glucose = [1,4-alpha-D-glucosyl](n+1)-L-tyrosyl-[glycogenin] + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:56560"/>
            <dbReference type="Rhea" id="RHEA-COMP:14606"/>
            <dbReference type="Rhea" id="RHEA-COMP:14607"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:140574"/>
            <dbReference type="EC" id="2.4.1.186"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the glycosyltransferase 8 family. Glycogenin subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.186" evidence="10"/>
    <dbReference type="EMBL" id="GG697339">
        <property type="protein sequence ID" value="EFQ27962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008091982.1">
        <property type="nucleotide sequence ID" value="XM_008093791.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QAS4"/>
    <dbReference type="STRING" id="645133.E3QAS4"/>
    <dbReference type="GeneID" id="24408471"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03106"/>
    <dbReference type="eggNOG" id="KOG1950">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017171_0_1_1"/>
    <dbReference type="OrthoDB" id="2014201at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008466">
        <property type="term" value="F:glycogenin glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02537">
        <property type="entry name" value="GT8_Glycogenin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000092">
        <property type="entry name" value="Glycogenin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002495">
        <property type="entry name" value="Glyco_trans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050587">
        <property type="entry name" value="GNT1/Glycosyltrans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11183">
        <property type="entry name" value="GLYCOGENIN SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01501">
        <property type="entry name" value="Glyco_transf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 14" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00050886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00052293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00057883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EFQ27962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="296" mass="32950" checksum="4667CCDE7C3FEF84" modified="2011-01-11" version="1">MGSLQPTTEDVAYCTLVTNDGYVVAAAVLAQSLRATGTRIPRCVIITPETMSEESIATLRGLFDRVIPVPAMAALTTTNLDLIGRPDLHATMTKLQLWSLAQFRRVLYLDADTLVLSNLDHVFELPESVTFAASPEIGFPDCFNSGVMLLRPDAATYAELTAFATRVDSFDGGDQGLLNVFFGDGTKNHPSTVLMRQKQQHGGKGAGEDSSAGERNWFRLSFTYNMEMHSVYRFYIPAALRYKDQHKVLHFIGKDKPWHYENGKVDTPDDAGAYHRFYADMVGKWWETRRSIAAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBE7</accession>
    <name>E3QBE7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_03430</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092306.1">
        <property type="nucleotide sequence ID" value="XM_008094115.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBE7"/>
    <dbReference type="STRING" id="645133.E3QBE7"/>
    <dbReference type="GeneID" id="24408795"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03430"/>
    <dbReference type="eggNOG" id="ENOG502QSHE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009942_1_1_1"/>
    <dbReference type="OrthoDB" id="3501663at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01300">
        <property type="entry name" value="YtcJ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033932">
        <property type="entry name" value="YtcJ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22642">
        <property type="entry name" value="IMIDAZOLONEPROPIONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22642:SF2">
        <property type="entry name" value="PROTEIN LONG AFTER FAR-RED 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178342" evidence="1">
        <location>
            <begin position="28"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydrolase 3" evidence="2">
        <location>
            <begin position="82"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ28286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="570" mass="62782" checksum="1205C74C9233CBF5" modified="2011-01-11" version="1">MSATPIARWGVGLSAAVAVVALAVVRLQQPLTGDIADTQTHCYQGVRTHDEDQPLAQCFTVSGGRFTRVFPWDDASLTTKAGYIIPGIWDGHGHLAQYGEFLYSADLFGSSSLDDVKGRLRLYVDSHADAGTKDEWIRGVGWDQNTYGRMPTAADIEEDELLKGKFFMLDRIDVHCTWVSQAVLDLLPADIPDVPGGEIVREPGMGVFCDNAMDLIYNLWPQPGPEKKKAFVAAAMAKLNEFGLVGIHDAGVFPDQLDLYADMARTDDWTVRVYAMLECAQRNTFCPDDAARVFREDDMFSVKSVKLFADGALGSWGSAMIEPYNDRPDTAGSLLVNGSTLKQLGRSWASVGYQVNIHAIGDLANRYAVDALEAGLRDACPTGDLAKCQAKRRFRIEHSQIIHEDDQRRIHAIGIIPSIQPTHATSDMKYAELRLGPERTKKEAYRMRSLLDVNPILGSDFPVEPPNPFQGIYAAVARKSPHTGYGVNGSVEGWHTEEALSLDEALLGFTKGPAFGAFMEGRAGVIKEGAFADWVVLDEPLENMDIEDIRDLKVKETWVGGKLVYERAHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3QBV2</accession>
    <name>E3QBV2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RNA recognition domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_03331</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092207.1">
        <property type="nucleotide sequence ID" value="XM_008094016.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QBV2"/>
    <dbReference type="SMR" id="E3QBV2"/>
    <dbReference type="STRING" id="645133.E3QBV2"/>
    <dbReference type="GeneID" id="24408696"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03331"/>
    <dbReference type="eggNOG" id="KOG4205">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012062_0_0_1"/>
    <dbReference type="OrthoDB" id="1875751at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12577">
        <property type="entry name" value="RRM1_Hrp1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12330">
        <property type="entry name" value="RRM2_Hrp1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000466">
        <property type="entry name" value="Heterogeneous nuclear ribonucleoprotein HRP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000025">
        <property type="entry name" value="RNA-binding protein Musashi homolog 2 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034156">
        <property type="entry name" value="Hrp1_RRM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48032:SF6">
        <property type="entry name" value="RNA-BINDING (RRM_RBD_RNP MOTIFS) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48032">
        <property type="entry name" value="RNA-BINDING PROTEIN MUSASHI HOMOLOG RBP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="83"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="156"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="275"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="182"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="275"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="301"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="334"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ28187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="445" mass="48170" checksum="219E49A9DCC3FC9C" modified="2011-01-11" version="1">MFIGGLNWETTDQSLRDYFSQFGEVVECTVMRDSSTGRSRGFGFLTFRDPKTVNIVMVKEHFLDGKIIDPKRAIPRDEQEKTSKIFVGGVSQETTDQEFKDYFAQFGRVVDATLMMDKDTGRPRGFGFVTFESEAGVDACLSTSLEIHGKPIEVKKAQPRGNLREEEEAARRGGKFRKGDDNAQSGQNGMGSTQMAAAGGMTPQVMAQYFQRMQQYFAMMQQQMAMSRGMGPMNPAMMQQMMQMQQMQQMQSQMMGRGGGGGNGQQGMMGQMTPQMMQQMQQMQQQMQQQMGQQGGPPSGPSGSFSPQQQMFDPSQGGQPQQQQQQQQPSQGPRRGGGGGGGGVPRDQYNQGGAYAMGGGGGAPTSWEGMYDDVPQPNLNQGGRGGYRGGHRGGSHSGGSHQGSPDPAHAPPANAPTGPKNAGRPGANYRGGGRSGNRGFHPYSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>E3QC31</accession>
    <name>E3QC31_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nitronate monooxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_03410</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092286.1">
        <property type="nucleotide sequence ID" value="XM_008094095.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QC31"/>
    <dbReference type="STRING" id="645133.E3QC31"/>
    <dbReference type="GeneID" id="24408775"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03410"/>
    <dbReference type="eggNOG" id="ENOG502RHJM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038732_7_1_1"/>
    <dbReference type="OrthoDB" id="2349068at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ28266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="139" mass="15279" checksum="4B22E08E70B08A0A" modified="2011-01-11" version="1">MDSAGFVMGTRFVATDEAASAQLHKEMIVRTRDGGVSTWKSHFHDKLVDSKLWNDEYDGRAVVGAIHSESRALGGDTATVEESREHLRTRWSEEEGKKMIGKWAGAGVGLVTEIKPAGEVVVEVREAARKRIQELAGMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>E3QC36</accession>
    <name>E3QC36_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_03415</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697340">
        <property type="protein sequence ID" value="EFQ28271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092291.1">
        <property type="nucleotide sequence ID" value="XM_008094100.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QC36"/>
    <dbReference type="GeneID" id="24408780"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03415"/>
    <dbReference type="HOGENOM" id="CLU_1555128_0_0_1"/>
    <dbReference type="OrthoDB" id="4850079at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ28271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="172" mass="18816" checksum="855F48A75E93933E" modified="2011-01-11" version="1">MSSHLQTSPGTQRSKKVPAVAHQVPGSDLDMASNDDMLLSAFDLTILPIFGENVGRSHTEAPRRYQHQHRSGTYCGQWAHAYEHRVRWNLYLATSTAQPYPGNMRPAAMVISPTINAWLLFPVIVSTRPFSPSSCLPTSMAPPSIFGTSTGTTTASISAHPMYPVWGTLVVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>E3QC73</accession>
    <name>E3QC73_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Glutamate 5-kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_03605</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the glutamate 5-kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092481.1">
        <property type="nucleotide sequence ID" value="XM_008094290.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QC73"/>
    <dbReference type="STRING" id="645133.E3QC73"/>
    <dbReference type="GeneID" id="24408970"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03605"/>
    <dbReference type="eggNOG" id="KOG1154">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025400_1_1_1"/>
    <dbReference type="OrthoDB" id="409889at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004349">
        <property type="term" value="F:glutamate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901607">
        <property type="term" value="P:alpha-amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd04242">
        <property type="entry name" value="AAK_G5K_ProB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21157">
        <property type="entry name" value="PUA_G5K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.130.10:FF:000008">
        <property type="entry name" value="Glutamate 5-kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1160.10:FF:000020">
        <property type="entry name" value="Glutamate 5-kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="entry name" value="Acetylglutamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="entry name" value="PUA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00456">
        <property type="entry name" value="ProB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041739">
        <property type="entry name" value="G5K_ProB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001057">
        <property type="entry name" value="Glu/AcGlu_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011529">
        <property type="entry name" value="Glu_5kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005715">
        <property type="entry name" value="Glu_5kinase/COase_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019797">
        <property type="entry name" value="Glutamate_5-kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01027">
        <property type="entry name" value="proB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43654">
        <property type="entry name" value="GLUTAMATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43654:SF3">
        <property type="entry name" value="GLUTAMATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01472">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000729">
        <property type="entry name" value="GK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00474">
        <property type="entry name" value="GLU5KINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="Carbamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00902">
        <property type="entry name" value="GLUTAMATE_5_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50890">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PUA" evidence="11">
        <location>
            <begin position="335"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="263"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="272"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00061601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ28461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="475" mass="51769" checksum="D51CE36DBFD40896" modified="2011-01-11" version="1">MKQHREGQKPQTVVLKLGTSSIVDEKTHQPLLSILSLIVETAVKLRKDGHRVVIVSSGAIGVGLLRMEMGRRPKHLSTLQALAAIGQCRLISLWDDLFSHFRQPVAQILLTRNDIADRTRYLNAQNTFNELLDMGVIPIVNENDTLAVSEIKFGDNDTLSAIAAGMVHADMLFLMTDVDCLYDKNPRTHPDAQAIEVVEDISSIQADVSTAGSSLGTGGMMTKIVAARLATSAGVTTVITRSSNPGNIVKIVRYIQAQQKSSPHLDATAIHDGGDHDTDHDHDHDHAEDPLSQSTASLRLDQAVEKPPLHTRFLPSAEPIRDRHFWLIHGLKPHGTLYIDAGAHSALLRKAGLLPAGVIDVDGNFAQQEAVRLVVVDRLHGPSAGQSGKRWGGTPVEVGRALVNYAAPEIMRIKGHQSSDIGGLLGYADSEYVAERQHIRIFSRESRPVTPSIEKAKEQIVEEVISGITGYEQKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QC74</accession>
    <name>E3QC74_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">60S ribosome subunit biogenesis protein NIP7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_03606</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Interacts with pre-ribosome complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the NIP7 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092482.1">
        <property type="nucleotide sequence ID" value="XM_008094291.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QC74"/>
    <dbReference type="STRING" id="645133.E3QC74"/>
    <dbReference type="GeneID" id="24408971"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03606"/>
    <dbReference type="eggNOG" id="KOG3492">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097217_0_0_1"/>
    <dbReference type="OrthoDB" id="27490at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902626">
        <property type="term" value="P:assembly of large subunit precursor of preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd21146">
        <property type="entry name" value="Nip7_N_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21151">
        <property type="entry name" value="PUA_Nip7-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.130.10:FF:000002">
        <property type="entry name" value="60S ribosome subunit biogenesis protein NIP7 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.220:FF:000001">
        <property type="entry name" value="60S ribosome subunit biogenesis protein NIP7 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="entry name" value="PUA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040598">
        <property type="entry name" value="NIP7_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055359">
        <property type="entry name" value="Nip7_N_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016686">
        <property type="entry name" value="Ribosomal_synth_fac_NIP7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005155">
        <property type="entry name" value="UPF0113_PUA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23415">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17833">
        <property type="entry name" value="pre-PUA_NIP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03657">
        <property type="entry name" value="UPF0113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017190">
        <property type="entry name" value="Rbsml_synth_fac_NIP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88802">
        <property type="entry name" value="Pre-PUA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50890">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="PUA" evidence="8">
        <location>
            <begin position="100"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00054591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR017190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ28462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="187" mass="21061" checksum="CA84E0FCE92A7160" modified="2011-01-11" version="1">MRPLTEKETETLFNKLASYMGSSLKNLIAPLDNGPEPDRYVFRMIRDRVYYVRLSVANLATSIARDKLLSIGICLGKFTKTGKFRLHVTALPILSEHARYKIWVKPNGEMPFLYGGNIVKAHVGRWSEDCPEHQGVIVFSMDDKPLGFGVTARSTAEARRLDPTGVVCFRQSDCGEYLRDEDTLFAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCH9</accession>
    <name>E3QCH9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_03711</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092587.1">
        <property type="nucleotide sequence ID" value="XM_008094396.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCH9"/>
    <dbReference type="STRING" id="645133.E3QCH9"/>
    <dbReference type="GeneID" id="24409076"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03711"/>
    <dbReference type="eggNOG" id="ENOG502SX2A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052402_1_0_1"/>
    <dbReference type="OrthoDB" id="4140442at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180307" evidence="3">
        <location>
            <begin position="25"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="60"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ28567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="342" mass="36845" checksum="49BF9AA5846F403F" modified="2011-01-11" version="1">MASFARGLGLGLSLLAPRTAPLCATPQPLQPFSRRFFGSITALRHAAKPPSSSRIATSVPRAATAPKTLTPKPKPTAPGPTRTVSPAAAVSSAGSAYALTAQLAQRSQPTVLYEAGSHFWMKLSAWAAMLMFYSYAGINYYTMLLHPPEDIAAWVPHAFAVICLAMAGFGSYFFYNTRNIVRLVRAVPTALLAPNARGLAPGAGAALNPKTTPIHLEITCKRMLPGRTKVLVVPPQQVSMPGRIVAQAAPSHASPARERAAARQEQARARAEWEYDKNHLMTVPFRHAGKGFRAAWYGIRRAVTREGFMQMEVGSHKLKLDVASGWALDDGRAIDRLVKIGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCM1</accession>
    <name>E3QCM1_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pyrroline-5-carboxylate reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_03753</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pyrroline-5-carboxylate reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092629.1">
        <property type="nucleotide sequence ID" value="XM_008094438.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCM1"/>
    <dbReference type="STRING" id="645133.E3QCM1"/>
    <dbReference type="GeneID" id="24409118"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03753"/>
    <dbReference type="eggNOG" id="KOG3124">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042344_1_1_1"/>
    <dbReference type="OrthoDB" id="10263291at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004735">
        <property type="term" value="F:pyrroline-5-carboxylate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3730.10:FF:000001">
        <property type="entry name" value="Pyrroline-5-carboxylate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.10">
        <property type="entry name" value="ProC C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01925">
        <property type="entry name" value="P5C_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029036">
        <property type="entry name" value="P5CR_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000304">
        <property type="entry name" value="Pyrroline-COOH_reductase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00112">
        <property type="entry name" value="proC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645">
        <property type="entry name" value="PYRROLINE-5-CARBOXYLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645:SF0">
        <property type="entry name" value="PYRROLINE-5-CARBOXYLATE REDUCTASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14748">
        <property type="entry name" value="P5CR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="Pyrroline-5-carboxylate reductase catalytic N-terminal" evidence="5">
        <location>
            <begin position="70"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="Pyrroline-5-carboxylate reductase dimerisation" evidence="6">
        <location>
            <begin position="220"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ28609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="343" mass="36520" checksum="674B69E2AC685050" modified="2011-01-11" version="1">MSVMGDHSSEELTVTVLGCGTMGIAILNGILTSLVEMQAPRPLQMLHTPSASGTSTPRHDEVPARLPSRFIACVRRSESAKKVKKALWEHSSILKVVQNDNVNSVYQSEVVILACKPYMVKELLSEPGMARALHGKLLISICAGLTETHLEEILHGAVPTKNPEEDGRCRVIRALPNTASLIREGMTVIGAPTYPLPPQTASLVTWIFRRIGDVVYLPANNMDASTALCGSGPAFFALMLEAAIDGAVAMGIPRVEAQRMAAQSMKGAACLVQNGDHPALLRDKCTTPGGCTIGGLLVLEEGRVRGTIARAVRESTVVASQLGQGVQGVNGTRFTPQSGYSQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCT9</accession>
    <name>E3QCT9_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FUN14 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_03821</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697341">
        <property type="protein sequence ID" value="EFQ28677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092697.1">
        <property type="nucleotide sequence ID" value="XM_008094506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QCT9"/>
    <dbReference type="STRING" id="645133.E3QCT9"/>
    <dbReference type="GeneID" id="24409186"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03821"/>
    <dbReference type="eggNOG" id="ENOG502RNQ3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106353_2_0_1"/>
    <dbReference type="OrthoDB" id="3990500at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ28677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="149" mass="16197" checksum="EE65C07CBA03EBD0" modified="2011-01-11" version="1">MSGLLSARLVGRRLVWPVGSGICVAYSLHCRQTSNYFNSHLTASASPTPRAQSRSFGGLSPDAMRQLSSGTLSGFSAGLLVGFLSHTLVLLTGLAMFIFYLAHRHGLDLPRLLGAKERLNKAVLTRPFHNVVFRLSFAATFTLAAFVRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>E3QCX7</accession>
    <name>E3QCX7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">1-phosphatidylinositol 4-kinase</fullName>
            <ecNumber evidence="3">2.7.1.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_03893</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19877"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57880"/>
            <dbReference type="ChEBI" id="CHEBI:58178"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.67"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.67" evidence="3"/>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092769.1">
        <property type="nucleotide sequence ID" value="XM_008094578.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QCX7"/>
    <dbReference type="GeneID" id="24409258"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03893"/>
    <dbReference type="eggNOG" id="KOG0902">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000893_1_0_1"/>
    <dbReference type="OrthoDB" id="10264149at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004430">
        <property type="term" value="F:1-phosphatidylinositol 4-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061909">
        <property type="term" value="P:autophagosome-lysosome fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006995">
        <property type="term" value="P:cellular response to nitrogen starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030866">
        <property type="term" value="P:cortical actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140504">
        <property type="term" value="P:microlipophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060237">
        <property type="term" value="P:regulation of fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00871">
        <property type="entry name" value="PI4Ka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05167">
        <property type="entry name" value="PI4Kc_III_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.70:FF:000011">
        <property type="entry name" value="Phosphatidylinositol 4-kinase alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1070.11:FF:000022">
        <property type="entry name" value="Phosphatidylinositol 4-kinase stt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1010.10:FF:000014">
        <property type="entry name" value="Phosphatidylinositol 4-kinase STT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.70">
        <property type="entry name" value="Phosphatidylinositol 3-kinase, accessory domain (PIK)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015433">
        <property type="entry name" value="PI3/4_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001263">
        <property type="entry name" value="PI3K_accessory_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042236">
        <property type="entry name" value="PI3K_accessory_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045495">
        <property type="entry name" value="PI4K_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048:SF15">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 4-KINASE ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00613">
        <property type="entry name" value="PI3Ka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19274">
        <property type="entry name" value="PI4K_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00145">
        <property type="entry name" value="PI3Ka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00915">
        <property type="entry name" value="PI3_4_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51545">
        <property type="entry name" value="PIK_HELICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PIK helical" evidence="9">
        <location>
            <begin position="1364"/>
            <end position="1550"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="8">
        <location>
            <begin position="1623"/>
            <end position="1918"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ28749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1934" mass="215245" checksum="DC4CAF7515F1056D" modified="2011-01-11" version="1">MTRDIRQRALEKIASLSATSSRTSFDRSDLDRLCKATQAAGKGVNGYSPKQPSTSLGRCPMTIREFEVLLSLCKAAPAIQTSQSAQKLAHQLIPYILEAHIQVFVPSPFFRKVEPSPTEALAFHVTAALLTLASHYDNLHEVVSDNIWTFINACNHAADHTVPLHADDEDPNLEDAIRTATIAVSLLGFLDAASAQADFWKAGGRMALLQRFRDILSESFLVAVETAFSTIRNSQSSDRHAREWKRYLRHYSAAGRPLGAILLQRSYMWLLVAGTSLLVTDASLLRGTHILDLLMSGEGAFRPGSPRSPDADYRSLDLYTTVAVDQMNYLEAGEDYLKLGSASQQRLAFAVKSAALISYLNCSLMNEEVADIDVLITWLEETLADPLQMADENLAATVLRSIALVCKISRGYAATASRLLPRFIVQSVPNARTVAVASKSLAYVLQMLSHDAVITTLYTLGNVLSPGSDRSMTNGTNGDLGADGANALYSNRQSTGSSISLAITGEEETAMVYGNVVQAICGVAAACNDEKITALAQSMLLQKIDKVNSNVDAQIISGAAALALKGGQLEFRSLLKVFSRVCHLGVVGHKDSLLAAVMKARTHISANLRRGSPLYDIYREHLLESIISMGDVHQSNHTKEADVQLAASEIAELLHPLAVFMSTNDLAFNSVTDDESHSMIRDAWFNIVVHGFTTQTDMGKKYLDELRIMAVHSPPLVAEQRGEQIESDIELNTVLRRGMSSDRESMQKKHLTELIPNKATEIKGLSYRKVIFLHAAYLVEGLRADAGDCTKALSYFLEPSMRKGEVSSTMEGIAAAVVNKYLRKTLGGTDATFSAQYAASQLVAIFCGCCHRIERVQQAAFTCADRIISQVPSALCHRSSLFALLELLSLMWSSCLEAETDLYAPRSKFTSELGDVSVELSDDYSFRRHTLEALNRRAKQWVSSVISLAPLDIKGLLQTYLSEFDDEGAYGHISLGRSFAIELGSLMPSADQRLQSLDRVGDCSINTGSDFIAQYTTRQEYRYGETLPERGNELVNFMQLNRRASFVKSSTSIASDSANAATALEHVEARIKSKKMTALAEVREILRRAAALLCRSDRDESAVAHYLVSIPFAMFTKQSIKLGVSLWLGVMNENPRLEPRLLTEIAQQWEVSIQNGLGLFSQAMSHTDPFFLKMEFAPSDLEALAKRKQQVHNLLSPHTRLLQFFASHFNATRLGSPDVQRIFLRMLDVTLDAVRLSTPHPMARELRFQIVLFGLKVLHVCTTIGAIAQWRFKEKILSAALSWFRFAPRWSFGSNILQLKTEIRLLNDVVAALKNVAFIGANAADTIKSLQAKEQLLVLLLESEQARLSVWVHPLGEQSKPHGQPNKTAIEAALSPLIRVAWAEDPSIAIELVTRFPYPRVQREVRWLLINFPQKAISEPQGLPILLGGSLPNDVSFQLKYLLFWSPVNPITAVTYFLPAYRNHPFLMQYAMRALESHSSDVTFFYVPQIVQTLRYDALGYVERYILETAQFSQLFAHQIIWNMKANAYKDDDATIPDAIKPTLDKVMEKMIASFSEVDRTFYEREFAFFDEVTDISGKLKPYVGRSKPEKAQKIEEELRKIKVEIGVYLPSNPDGVVIGIDRKSGKPLQSHAKAPYMATFRIKKNKGSLEDVNDMLEDAHKKDSPPMPENTIEVWQSAIFKVGDDCRQDVLALQMIAAFRGIFHNVGLDVYVNPYRVTATAPGCGVIDVLPNSVSRDMLGREAVNGLYDYFISKYGNEDSLRFQQARSNFVKSMAAYSIISFLLQFKDRHNGNIMIDDAGHILHIDFGFCFDIAPGGIKFERAPFKLTTEMLAVMGGNPHHQAFKWFEELCVKAFLASRQHCEKLSQIVLLMMDSGLPCFKPESVQHFKERFVLDRSEREAADFVKDLIRRSANSYSTGVYDQFQLLTNGIPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>E3QD37</accession>
    <name>E3QD37_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA polymerase lambda</fullName>
            <ecNumber evidence="4">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">GLRG_03953</name>
    </gene>
    <organism evidence="21">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="22">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DNA polymerase type-X family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="4"/>
    <dbReference type="EMBL" id="GG697342">
        <property type="protein sequence ID" value="EFQ28809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008092829.1">
        <property type="nucleotide sequence ID" value="XM_008094638.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QD37"/>
    <dbReference type="STRING" id="645133.E3QD37"/>
    <dbReference type="GeneID" id="24409318"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_03953"/>
    <dbReference type="eggNOG" id="KOG2534">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008698_3_0_1"/>
    <dbReference type="OrthoDB" id="205514at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00141">
        <property type="entry name" value="NT_POLXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000010">
        <property type="entry name" value="DNA polymerase lambda"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.210.10:FF:000001">
        <property type="entry name" value="DNA polymerase lambda"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.110:FF:000005">
        <property type="entry name" value="DNA polymerase POL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.110">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.210.10">
        <property type="entry name" value="DNA polymerase, thumb domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002054">
        <property type="entry name" value="DNA-dir_DNA_pol_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028207">
        <property type="entry name" value="DNA_pol_B_palm_palm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018944">
        <property type="entry name" value="DNA_pol_lambd_fingers_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027421">
        <property type="entry name" value="DNA_pol_lamdba_lyase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037160">
        <property type="entry name" value="DNA_Pol_thumb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022312">
        <property type="entry name" value="DNA_pol_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002008">
        <property type="entry name" value="DNA_pol_X_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010996">
        <property type="entry name" value="HHH_MUS81"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029398">
        <property type="entry name" value="PolB_thumb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11276:SF28">
        <property type="entry name" value="DNA POLYMERASE LAMBDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11276">
        <property type="entry name" value="DNA POLYMERASE TYPE-X FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14792">
        <property type="entry name" value="DNA_pol_B_palm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14791">
        <property type="entry name" value="DNA_pol_B_thumb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10391">
        <property type="entry name" value="DNA_pol_lambd_f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14716">
        <property type="entry name" value="HHH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00869">
        <property type="entry name" value="DNAPOLX"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00870">
        <property type="entry name" value="DNAPOLXBETA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00483">
        <property type="entry name" value="POLXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47802">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81585">
        <property type="entry name" value="PsbU/PolX domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0227">DNA damage</keyword>
    <keyword evidence="13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="6" id="KW-0237">DNA synthesis</keyword>
    <keyword evidence="12" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="14" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BRCT" evidence="19">
        <location>
            <begin position="189"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="51"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="112"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="301"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="301"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="332"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="368"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="379"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; Schiff-base intermediate with DNA; for 5'-dRP lyase activity" evidence="17">
        <location>
            <position position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR622312-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EFQ28809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="819" mass="92179" checksum="BEC2AD1330C1DAEF" modified="2011-01-11" version="1">MADTNTSFRDKARFFRQLESLGRQNDDIDSDEFQDAELRHRQQLKAFQAAVQPRQTLQERAQQEPQLQSQSSTPQQLISDLRGTSSIPVPVPSSFTDLRQKKVIERTPLAEIKGPGRKDAPAADSFIEDTPVPDSSIRPPLLPISTLTKRVTTPLPATKHILPRLVDNSPSVAAMKKRKRDPPIKTVPEEQQVFRGLRFYFIPNDDIAPARKVRIRKAQEFGASWVRSLKTASHVIVDRNLNWKSIESIVRPTNGAASYLVLNEEYPLDCLKFKTLLNANQKQYRVPGSPELSAAPAEPQIGSQVGQPLAPTSQDSPLEPRQVNPKQRDYVQPSTPLRSLRSSGMTKGKDANATSPSALRDITEIVLPSSIPGGSSQSIDDDDDDDDEMPATIEKQTLGLEDELEDVISQMQEFRDLPLEHDDDDMAVSMQSPDEAFDVEGSEDERLRKKKVATRSRGRKDMAWEDKFACHRGGTNGGGQTNPNGRTIEILQQMCNYYERVNDTWRPIAYRKAITQLKRQPSKISTAEEAIRLPGVGQRLADKIEEIVTTNRLQRLESAEQEPMDKVLQMFLNIYGVGSVQASHFVSQGFRTLEDLKEKAKLTPNQRIGIDHYDDLNTRIPRSEVKLLGAVVRSEAAKLDPSVQLIIGGSYRRGALDSGDVDFIITKKGARATSDLTPFLHKLVKTLETQNFLVARLAGSRDETDGSKWHGCCVLPKIRGVNDENYRRVWRRVDFLVVPETEIGAALIYFTGNDIFNRSIRLLASKKGMRLNQKGLYKDVMRGPGRVKLTEGELVEGQDERRIFEILGVKWREPHERWC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QE04</accession>
    <name>E3QE04_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_04236</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093112.1">
        <property type="nucleotide sequence ID" value="XM_008094921.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QE04"/>
    <dbReference type="GeneID" id="24409601"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04236"/>
    <dbReference type="eggNOG" id="ENOG502RZW2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098356_0_0_1"/>
    <dbReference type="OrthoDB" id="5423111at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032126">
        <property type="term" value="C:eisosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070941">
        <property type="term" value="P:eisosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072659">
        <property type="term" value="P:protein localization to plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008253">
        <property type="entry name" value="Marvel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052649">
        <property type="entry name" value="NCE102-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28165">
        <property type="entry name" value="NON-CLASSICAL EXPORT PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28165:SF1">
        <property type="entry name" value="NON-CLASSICAL EXPORT PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01284">
        <property type="entry name" value="MARVEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="MARVEL" evidence="6">
        <location>
            <begin position="6"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ29092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="173" mass="18628" checksum="94404A63E8A53EF7" modified="2011-01-11" version="1">MMDSMLPVLVRGLQILWVLLVTALIGNVIALNINSAGSAMAAINFSMFVAVVCWLASLYGLAAAFVSAIAIPIVLLALDGAAVLFTFIDAIVLSAKLRAVNCGSLNRRDLPGNYIVWGSADDEKRCREIQASTVFMWFLFASFCAGGFFTFMNFRRGGGSMRSSRPSMAQVDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3QE62</accession>
    <name>E3QE62_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mmc protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04294</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697343">
        <property type="protein sequence ID" value="EFQ29150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093170.1">
        <property type="nucleotide sequence ID" value="XM_008094979.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QE62"/>
    <dbReference type="STRING" id="645133.E3QE62"/>
    <dbReference type="GeneID" id="24409659"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04294"/>
    <dbReference type="eggNOG" id="ENOG502S7XK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092869_4_0_1"/>
    <dbReference type="OrthoDB" id="4094614at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005199">
        <property type="term" value="F:structural constituent of cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038843">
        <property type="entry name" value="Sed1/Spi1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35523">
        <property type="entry name" value="CELL WALL PROTEIN SED1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35523:SF1">
        <property type="entry name" value="CELL WALL PROTEIN SED1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003179653" evidence="1">
        <location>
            <begin position="18"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="142" mass="13992" checksum="371E303BCB85540B" modified="2011-01-11" version="1">MKFSAAALVLAATGALAHKNVTYVTEVVSSYTTYCPAATVITHGDKTYTVTSATTLTITDCPCTVTKPVITSAVVQCDNCAAPTKNGTVPIATPVISKPTIPATGAITPTKPVSVPTAGAGKAAALSGAGLAGVLGIAAFVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEM5</accession>
    <name>E3QEM5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_04475</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093351.1">
        <property type="nucleotide sequence ID" value="XM_008095160.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEM5"/>
    <dbReference type="STRING" id="645133.E3QEM5"/>
    <dbReference type="GeneID" id="24409840"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04475"/>
    <dbReference type="eggNOG" id="KOG1515">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1835018_0_0_1"/>
    <dbReference type="OrthoDB" id="2152029at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ29331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="140" mass="15499" checksum="A98A94ADD45E85A8" modified="2011-01-11" version="1">MVSPLLTFRTETASFRENGHVDMLSAAIVSRGNTYIFAAESLKRQVANPHRPLPLDGDPEWFGEVQTVAKAVYFTAGGQEVFRDDVRAFAEAVRRCNPDVDFKLDVAANEVHDSILLEAELGVAGDATKRMRQWTSKCLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QET4</accession>
    <name>E3QET4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Signal peptide-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04534</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093410.1">
        <property type="nucleotide sequence ID" value="XM_008095219.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QET4"/>
    <dbReference type="GeneID" id="24409899"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04534"/>
    <dbReference type="eggNOG" id="ENOG502SM8K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036638_1_0_1"/>
    <dbReference type="OrthoDB" id="506431at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="104"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="236"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="297"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="389"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="418"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="429" mass="47314" checksum="2CAC4B24E8F2EB9D" modified="2011-01-11" version="1">MSLPVAIQSAIFYYLACTPCNEMKAFRKAKKKAKEDREIKRKIEMEQPGLYSHPDPFHTNPFWAEEMAAGPHLPKKSGSKNTSQRGLASAGRASTTASFGCASTVADTTSPATPTTSTETARKLSGDGWNRALYQREDEELWGHNFTGMGHKLMDNIAKAGNTAGRYVEEKLGLEKPITDEDRDNFYRTPKNPPVNEYHPPIVGSKPSRPDALKWMLQPPPPAKLMEGRVPVARTVSTSTVGSRRTMASEEPPLDRVVRERAIRKKLRQGEKPRKEETPSESELIESLIGGRSRRATVSSRGLSTRSRSLSLESEVSSDGELVERRRLARARRVPMTPEESSSDDDFTQHRTWDSLGKSSPRKRPQLETINSSRANTREALRARQNGTKADAASKASSDITPKASANPIATRTADENTPTTVTAATTVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>E3QEV3</accession>
    <name>E3QEV3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLRG_04553</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697344">
        <property type="protein sequence ID" value="EFQ29409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093429.1">
        <property type="nucleotide sequence ID" value="XM_008095238.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QEV3"/>
    <dbReference type="STRING" id="645133.E3QEV3"/>
    <dbReference type="GeneID" id="24409918"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04553"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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        <property type="entry name" value="Cytochrome P450 monooxygenase"/>
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        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
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        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
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        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
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        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF230">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="EP450I"/>
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        <property type="entry name" value="P450"/>
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        <property type="entry name" value="Cytochrome P450"/>
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    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180367" evidence="10">
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            <begin position="21"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="423"/>
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        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
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        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
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            <dbReference type="ARBA" id="ARBA00001971"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
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            <dbReference type="ARBA" id="ARBA00023002"/>
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            <dbReference type="ARBA" id="ARBA00023004"/>
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    </evidence>
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        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
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    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EFQ29409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="478" mass="54386" checksum="A982348EF33ECFCA" modified="2011-01-11" version="1">MATHQGLAGLLLMILYNVTLHPLRKYPGPKLWAATRIPYALMIIRGDPHKTILNLHQRYDTDIVRISPNELSFQHPDAWKDIMGHRSQSGENEKDPDIVEERRIDIISAGRRDHARYRRILSHSFSARSMQDQQPIILTYIDLFMKRLRSAAGQGPVDMVKWYNSTTFDIIGDLTFGESFGCLESSTSYHPWVRVIFENIKMLSLINLARSFWILAPLLKMLVPRDLIEKGKSHRAFVREKVDRRMALGTPRPDFAESMLKKGNEPLSQEEIYENSGLLVIAGSETTATALSGATYLLATNPDALARLSSEVRGSFASEDEIDLLSTAKLVYLNAVLEETLRMYPPVPTAVPRRTPPEGAEILGRWIPGNTTIGIAHWALYHNERLFSRPFGFHPERWLGGDPAFAGDRLDALRPFHVGPRNCLGMNLAYAEMRVMLARVIWAFDLRLDEASRDWTDQSCYIVWSKTPLMIHLKPRQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFG8</accession>
    <name>E3QFG8_COLGM</name>
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        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_04750</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EFQ29606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008095435.1"/>
    </dbReference>
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    <dbReference type="eggNOG" id="ENOG502TDI9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_152062_1_0_1"/>
    <dbReference type="OrthoDB" id="4820010at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178427" description="Secreted protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ29606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="108" mass="11455" checksum="CE3399B5FFBC6675" modified="2011-01-11" version="1">MQSALVLLATLLAGANACANYNKCHCTNADGSANDTITAVVCNNSNKLAPSSPGWPLYSEDEDSVMKCVLNTGPHNDFVGIDNCKFREFCTKAGATGSDSFCEVNRKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFH7</accession>
    <name>E3QFH7_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GRIP domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_04759</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EFQ29615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_008095444.1"/>
    </dbReference>
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    <dbReference type="STRING" id="645133.E3QFH7"/>
    <dbReference type="GeneID" id="24410124"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04759"/>
    <dbReference type="eggNOG" id="ENOG502S0A5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002906_0_0_1"/>
    <dbReference type="OrthoDB" id="1926336at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.330">
        <property type="entry name" value="Nucleotidyltransferases domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000237">
        <property type="entry name" value="GRIP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43941">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01465">
        <property type="entry name" value="GRIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00755">
        <property type="entry name" value="Grip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75704">
        <property type="entry name" value="Mitotic arrest deficient-like 1, Mad1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50913">
        <property type="entry name" value="GRIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GRIP" evidence="2">
        <location>
            <begin position="1100"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="430"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="493"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1019"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1069"/>
            <end position="1101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="449"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="505"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="530"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="543"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="585"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1026"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1036"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1075"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1085"/>
            <end position="1101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ29615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1157" mass="128977" checksum="A987BAE0D6195938" modified="2011-01-11" version="1">MFQRLKGAIDRTIAEEQARQEQARQRIEPGGATPRRSESTSRSNQSSARRPKKAAADALKDDTAASPSNTDPAVFEAAFALDDSEEPSRAGTPKPAPDAMDKGDEKPKNKAEEGQNGDADKDNEKDKPSEGAPAPAAAGADAAPTAAAAAPELSPEIRMKLRKLEKLEKTYPELLRSYRIAHTRATSIEPFERVLKEHTSVGSIREPEGLVEYLNSLKQKEQMIMDEYKRVSIEKDDFKKKFEAAEKDVEKFKKEVDELRAAQSAVPAARDEPDEAKEQVDAATSTKDDAAAVKSPLQQALGIFSPKQKAQEPEGAKPDESGADFFSYDEEAPKYEADMAAKDGEIEKLKAEIDSLKADLASAQDSSADLTEKFDKVTKEAGELRDIAAVKTSLETQLEARNKEIKSLTERLETSQKQLKEVEAKLKGEVESAKKDAKAVQSKLNESNARADREEARAKEAVAAKTQVEKKIETLNGQIENIKKAKAEHEKNIAELTKQLEKQQAAETAPPATPTATGPTDTSSPGMSKNAKKNNNKKKKKAGAAAAAAANAATTTTTTTTTAGTATPAAAEEAKESDTEALEAEITRLKEEVTTKDSQIERLTKQRKTEEDLREEIETLRDEVTEIGQEHVVAKEKIKNLEAEKKALEARIAELEKELGSSAGDAEAKEKLQSEFDKLQSEYDDLKSKSSTLQSDLGAAQQLAQTRFKDLTELREVLQRAQPEMKALRQDSAALKTAKEELAAKNTELRNLEKKERDLKSDVARVQRLATDRETEIKTLREKLTGETNNRLRLEDAQRVSARDLRRSEVEKVEISAREEKTARELQKVQEEANKLRPRVQELEEQVEKLEKEKKSLQEEADLKTQQYANAQGLLGSMRDQTGELTIQLKEARAQSESLEEELAEIQKHLSERSREAERMRGLLADVDERADSKVREMRARMEAAIEERDRIEDESSTLARRRARETEELKQKVRDLEREVKTLAGAKEELEGKEREWRRRREELELVEERATAEVEEMRSAVSDLRSTLDASEQQVREAERQKSDLRRLLEDSKQRFDKVSKELKTVQGKLGASVTSGRSSMDSNRSGGPNGAASGAAAPGASADTMYLKTIMLQFLEQKDNKLREQLVPVLARILKFDKTDEQKWKRAIQHITVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFI2</accession>
    <name>E3QFI2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Alpha-L-arabinofuranosidase</fullName>
            <ecNumber evidence="11">3.2.1.55</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">GLRG_04764</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Alpha-L-arabinofuranosidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>Hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides.</text>
            <dbReference type="EC" id="3.2.1.55"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the glycosyl hydrolase 62 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.55" evidence="11"/>
    <dbReference type="EMBL" id="GG697345">
        <property type="protein sequence ID" value="EFQ29620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093640.1">
        <property type="nucleotide sequence ID" value="XM_008095449.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFI2"/>
    <dbReference type="STRING" id="645133.E3QFI2"/>
    <dbReference type="GeneID" id="24410129"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04764"/>
    <dbReference type="eggNOG" id="ENOG502QUZT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041805_0_0_1"/>
    <dbReference type="OrthoDB" id="3156236at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046556">
        <property type="term" value="F:alpha-L-arabinofuranosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046373">
        <property type="term" value="P:L-arabinose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08987">
        <property type="entry name" value="GH62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005193">
        <property type="entry name" value="GH62_arabinosidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40631">
        <property type="entry name" value="ALPHA-L-ARABINOFURANOSIDASE AXHA-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40631:SF1">
        <property type="entry name" value="ALPHA-L-ARABINOFURANOSIDASE AXHA-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03664">
        <property type="entry name" value="Glyco_hydro_62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00562">
        <property type="entry name" value="CBM1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 11 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 11 13" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003178428" description="Alpha-L-arabinofuranosidase" evidence="13">
        <location>
            <begin position="27"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="14">
        <location>
            <begin position="353"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="327"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="327"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="337"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EFQ29620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="389" mass="41049" checksum="C9B1AE646D2684EC" modified="2011-01-11" version="1">MRLFQSNTDLLSAGIALLASAGAAVAQCSLPSTYRWSSSGVLATPKSGWVSLKDFTTVPYNGQHLVYGTTHNFGDSWGSMNFGLVSSFSQLGSVAQNTMSFGAVAPSLFYFAPKSIWVLAYQWGGNGAFSYRTSTNPASVSSWGGVQPLFTGTISGSGTGPIDQALIGDSTNMYLFFCGDNGKIYRASMPIGNFPGNFGSASTIILSDTTDNLFEAVQVYTLQGQQRYLMIVEAIGSQGRYFRSFTATSLGGAWTVQAGSESNPFAGKANSGATWTNDISHGELVRVSADQTMTIDPCKLQLLYQGRSPSSDGVDYGLLPYRPGLLTLTNPTGGSPPNTPPSTSPTTPPPSSGTVPQFGQCGGQGWTGGTVCQSPYKCTVSNQWYSQCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>E3QFN9</accession>
    <name>E3QFN9_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">STE24 endopeptidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_04868</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093744.1">
        <property type="nucleotide sequence ID" value="XM_008095553.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QFN9"/>
    <dbReference type="GeneID" id="24410233"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04868"/>
    <dbReference type="eggNOG" id="ENOG502S3NW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_173507_0_0_1"/>
    <dbReference type="OrthoDB" id="5341873at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ29724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="87" mass="9726" checksum="B4622CBA20423B88" modified="2011-01-11" version="1">MPTPLDNAMKSRSAVLAFGGLVTAAAVWAIYGGDMFPAAPDPTGNPENWTREEMRRWLAARNLFPNDNDKREELLARVLANMRAPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3QG02</accession>
    <name>E3QG02_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA pseudouridine(55) synthase</fullName>
            <ecNumber evidence="3">5.4.99.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_04981</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a uridine in mRNA = a pseudouridine in mRNA</text>
            <dbReference type="Rhea" id="RHEA:56644"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:14659"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pseudouridine synthase TruB family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.25" evidence="3"/>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093857.1">
        <property type="nucleotide sequence ID" value="XM_008095666.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QG02"/>
    <dbReference type="STRING" id="645133.E3QG02"/>
    <dbReference type="GeneID" id="24410346"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_04981"/>
    <dbReference type="eggNOG" id="KOG2529">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032087_4_1_1"/>
    <dbReference type="OrthoDB" id="9995526at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160148">
        <property type="term" value="F:tRNA pseudouridine(55) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990481">
        <property type="term" value="P:mRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02867">
        <property type="entry name" value="PseudoU_synth_TruB_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01080">
        <property type="entry name" value="TruB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002501">
        <property type="entry name" value="PsdUridine_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014780">
        <property type="entry name" value="tRNA_psdUridine_synth_TruB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13767:SF2">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE TRUB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13767">
        <property type="entry name" value="TRNA-PSEUDOURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01509">
        <property type="entry name" value="TruB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Pseudouridine synthase II N-terminal" evidence="7">
        <location>
            <begin position="69"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="225"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="391"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="235"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="399"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="421"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="482"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ29837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="502" mass="56599" checksum="372BAEC5334DFDEF" modified="2011-01-11" version="1">MAKDTVLEGVFAINKPYGMSSAQVIRDCQTQMNPSALFKPLIEKDLASKMREPKAEWKRRRAVKRDSRVKMGHGGTLDPLATGVLILGVGSGTKSLGSFLDCKKTYETVVLFGASTDTYDRVGRILSRRQYDEITRDNVEKALGDFRGKFQQIPPLYSALKMEGKPLYEYAREGKAIPREIAGREVEVTELEMVEWYEPGTHNYRWPTEEAEAAEKNLAEQVWRVEKQQGSGRKLTPDEEKEEERALSEHETVKKKFEERQDGLIRDKPAKKQKPPKNPALMSGALGQLPAGKGSNLIPPPPSADEPFPWTDKGPPAARIRMTVTSGFYVRSFCHDLGAKVNSAGLMAELERSRQGDFEVRTDNCLEYEDLLKGEQVWGPKVTQMLTAWSEKYPNGAPQGPQRRQNNQEQQNQSRKQDRKRKWEDNKKVDKSDENDRKRRNSSSGDEAPASKVARTEEAKGSPNTSPKGSLKSFPEGSPKVKAADTKKKLKPEEIEWEGFQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QG35</accession>
    <name>E3QG35_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Replication factor A protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_05014</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the replication factor A protein 3 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093890.1">
        <property type="nucleotide sequence ID" value="XM_008095699.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QG35"/>
    <dbReference type="STRING" id="645133.E3QG35"/>
    <dbReference type="GeneID" id="24410379"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05014"/>
    <dbReference type="eggNOG" id="ENOG502SBIR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141922_2_0_1"/>
    <dbReference type="OrthoDB" id="188186at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005662">
        <property type="term" value="C:DNA replication factor A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04479">
        <property type="entry name" value="RPA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013970">
        <property type="entry name" value="Rfa2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15114:SF1">
        <property type="entry name" value="REPLICATION PROTEIN A 14 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15114">
        <property type="entry name" value="REPLICATION PROTEIN A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08661">
        <property type="entry name" value="Rep_fac-A_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ29870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="108" mass="11646" checksum="1B3ADA3D6636405B" modified="2011-01-11" version="1">MAEATSTPRITAQYLDNYVGRNVMLIGKVLQLRGDSAVLDSDGSVTAILNRDVHLTNGNGAQVIGKVNPDLSIKVLSSRDLGPNVDYQLASAVVEATHHHKSLFVYEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>E3QG44</accession>
    <name>E3QG44_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase</fullName>
            <ecNumber evidence="10">2.7.8.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLRG_05023</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>a CDP-1,2-diacyl-sn-glycerol + sn-glycerol 3-phosphate = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12593"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:60110"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="2.7.8.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Phospholipid metabolism; phosphatidylglycerol biosynthesis; phosphatidylglycerol from CDP-diacylglycerol: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the CDP-alcohol phosphatidyltransferase class-II family.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.5" evidence="10"/>
    <dbReference type="EMBL" id="GG697346">
        <property type="protein sequence ID" value="EFQ29879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008093899.1">
        <property type="nucleotide sequence ID" value="XM_008095708.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QG44"/>
    <dbReference type="STRING" id="645133.E3QG44"/>
    <dbReference type="GeneID" id="24410388"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05023"/>
    <dbReference type="eggNOG" id="KOG3964">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030471_1_1_1"/>
    <dbReference type="OrthoDB" id="10250191at2759"/>
    <dbReference type="UniPathway" id="UPA00084">
        <property type="reaction ID" value="UER00503"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008444">
        <property type="term" value="F:CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032049">
        <property type="term" value="P:cardiolipin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd09135">
        <property type="entry name" value="PLDc_PGS1_euk_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09137">
        <property type="entry name" value="PLDc_PGS1_euk_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016270">
        <property type="entry name" value="PGS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12586:SF1">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12586">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--SERINE O-PHOSPHATIDYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000850">
        <property type="entry name" value="Phospholipase_D_PSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 10" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="11">
        <location>
            <begin position="153"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFQ29879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="492" mass="54388" checksum="3371AA8F6D9A3B44" modified="2011-01-11" version="1">MPSAGTPSASNSGSAAGMLAPFANELDKIAPSFSVNGSQIQIIRTPADFYETLKERIRNAKRRVFLSTLYIGKTEKELVATLQEALRNNPELKLSILTDALRGTREEPNPSCASLLAPLVFEFGADRVEIRMYHTPNLTGVRKKYIPKRINEGWGLQHMKLYGIDDEIILSGANLSSDYFTNRQDRYHLFSSKDVTDYFWNIHHGVSSFSFLVEPSKEAAGFTLTWPKSNPAPSPLEEPKQFIGTTTPTLDALISPKQSASADAGKDTKVYMLAQLSQLMKPDTSTELPAITHVLSTLSKPEYSGSSWTFTAGYFNPAPSLTKLLLSTASRNNVVITASQQANGFYQSPGVSGLLPGAYTLLARRFIRAVHERGLDDSIVLKEWRKGTVGEPGGWTYHAKGLWITLPGDQNPSISIVGSSNYTKRSYSHDLEAGAMILTKDEDLKKRLGQEQTWLQEHAERVTREDFSKNERRVGLQVRLAMWIAQAVGGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHG8</accession>
    <name>E3QHG8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="4">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">GLRG_05474</name>
    </gene>
    <organism evidence="20">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4"/>
    <dbReference type="EMBL" id="GG697348">
        <property type="protein sequence ID" value="EFQ30330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094350.1">
        <property type="nucleotide sequence ID" value="XM_008096159.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHG8"/>
    <dbReference type="STRING" id="645133.E3QHG8"/>
    <dbReference type="GeneID" id="24410839"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05474"/>
    <dbReference type="eggNOG" id="KOG0578">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_26_1_1"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008349">
        <property type="term" value="F:MAP kinase kinase kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071470">
        <property type="term" value="P:cellular response to osmotic stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019236">
        <property type="term" value="P:response to pheromone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001402">
        <property type="term" value="P:signal transduction involved in filamentous growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01093">
        <property type="entry name" value="CRIB_PAK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06614">
        <property type="entry name" value="STKc_PAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000011">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000385">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.810.10:FF:000007">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.810.10">
        <property type="entry name" value="CRIB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000095">
        <property type="entry name" value="CRIB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036936">
        <property type="entry name" value="CRIB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051931">
        <property type="entry name" value="PAK3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033923">
        <property type="entry name" value="PAK_BD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45832">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45832:SF22">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE SAMKA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00786">
        <property type="entry name" value="PBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00285">
        <property type="entry name" value="PBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50108">
        <property type="entry name" value="CRIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="9 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0589">Pheromone response</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CRIB" evidence="18">
        <location>
            <begin position="342"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="17">
        <location>
            <begin position="687"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="456"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="597"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="23"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="50"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="130"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="627"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="644"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="716"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EFQ30330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="967" mass="105135" checksum="9F4FB34AD6F3E246" modified="2011-01-11" version="1">MDGTQGTTVSNGTSQRRKLTKKPPSSYQQHTRSSSGLDGGIDALSLQSKRSSTSLRRAPSAPPARTTPSNAAAAASAAIHPGVASSAASNNSSPRHLPSSQTHLPNPSPILPQGQFAGAAPSPTAYHHPQTQTQTQTQAQTSTFHGHANASTAFSPHIHQNFNLPSNFYQNNNNNTTTTYTTNNNSAAGNGVGVGIAHSSDRPVDPTAITLSSQTHDDFIGAPFDGAAVLNRIEQTKSPVAAQPQPHQPFYQRHNAPPPPLIKSATDSRIRGPALRQSRSFTNDFSMMNEKSQGGRVTDNSMISPKRYSDEAKEPRMGVLRKKSGFSGFMNSLVGTPKKPVISAPENPVHVTHVGYDSSTGQFTGLPKEWQRLINESGIPEKERRENPQTMVDIITFYKETTEKPAEDQVLEKFHDARAPDYRQYASSNSPSGAMSPGMYPPTAYMGMSPMISPPASPRFPTVNHEGSFENPRQPPPVPGVGGGKGSSNKDINLMPSRPAPKPPVSLPMRSAPSTYPAKDSGIGMSQPGEDLPPVAYQPPKDNVPMLPEEHRGEHRSRSRSNSRVGATPGYVPPTPNPQNAQASLYQQQLMQQQQEQALAQAQAAMSGQISRAPSKRQPTQQPTPPQSQHQHPQGPTANGGPGQRQQVGVPGAPGSRPRHRPRQSTGIDVVAALKRICSDGDPRDVYKNFNKIGQGASGGVYTGYERGTNRLVAIKQMNLEQQPKKDLIINEILVMKDSSHPNIVNFIDSYLCGGELWVVMEFMEGGSLTDVVTFNIMTEGQIASVCRETLKGLQHLHSKGVIHRDIKSDNILLSMEGNIKLTDFGFCATINEAQNKRTTMVGTPYWMAPEVVTRKEYGRKVDIWSLGIMAIEMIEGEPPYLTESPLRALWLIATNGTPHIKEESNLSPVFRDFLYFALKVDPEKRASAHDLLRHEFMKGCVDLSQLSPLVRAAREARLAEKARKGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHH5</accession>
    <name>E3QHH5_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_05290</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697348">
        <property type="protein sequence ID" value="EFQ30146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094166.1">
        <property type="nucleotide sequence ID" value="XM_008095975.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHH5"/>
    <dbReference type="STRING" id="645133.E3QHH5"/>
    <dbReference type="GeneID" id="24410655"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05290"/>
    <dbReference type="eggNOG" id="KOG0192">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1481874_0_0_1"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050339">
        <property type="entry name" value="CC_SR_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="115"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="157"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ30146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="182" mass="19833" checksum="50190C61E8485D9F" modified="2011-01-11" version="1">MVMDLAAGLAFLHENGIVHRDVKPDNLLVCDSLQRKSLQPWGIAPVMLKLCDFGCSVILSDYNQGYVFTHTVGTPGWMAPEVEQGLPVDSGLLFKTDLYSLGLVAAHIFKSRRLSPSPGPDLRTTPADVRARKRKHGERDEGDESVDGLSILAEQPDVTTQRANKNDQGIGKGTTGPLANRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QHR0</accession>
    <name>E3QHR0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Tetratricopeptide</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLRG_05542</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697349">
        <property type="protein sequence ID" value="EFQ30398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094418.1">
        <property type="nucleotide sequence ID" value="XM_008096227.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QHR0"/>
    <dbReference type="STRING" id="645133.E3QHR0"/>
    <dbReference type="GeneID" id="24410907"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05542"/>
    <dbReference type="eggNOG" id="ENOG502RVQK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_327884_0_0_1"/>
    <dbReference type="OrthoDB" id="206201at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00306">
        <property type="entry name" value="Peptidases_S8_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="612"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="78"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="4">
        <location>
            <begin position="503"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="363"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFQ30398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="714" mass="83181" checksum="6C0BF13AA3325D12" modified="2011-01-11" version="1">MTKVGSGAVDWTTTAVDSSPEHSSLENRTNLSLQDFNRAIREAAQMKKTDPSRAAKLILDAMLWDIIKKLPRDNFDIVVARHHLGECYFLMGNYGEAERFYRQVLQARRSQKPPDSSKILQARQDLTASLIQSAMEEETRNVARAEKLHFEALSLAVKNMNEEDNDIRGEDIDDVLHCTKVLLKSQDRKPLELAKLSRTRVRALVQIEDDMDDEELIDMQHHGIVAFKHFTVDLEDRKSGYEVYNTVQSRIREYGAQDPDQSEMAVCIGDEVEDEWRKATGFLARKRWRRCLGQVRAEVRRDVLPQKKEIRDKWHLSCRRLMVKQRWKRALSEAKKTARRNINCHRKLVIDQWNSLVQEALQRKKEEENRKKDEERKGLKEEAKKRKREEGQQKKRDEEQRRLEHEEDKRKRENEEKQMAEERERKRNEEGKRLEEEDKRRTDDENRVKRLGGEREHETRKKEFEDKRGEEEEQERKREGKEEEALKRQMNMQNDFEIQQGISRTDTGYSEWSEPAVGRANWENKILFAAAGNFGNSKANVSFPARFPGVFKIFATDHQGGKCSFSPSPDLEKSYCFSILGHDVVSIWPEAVRDKDRETPLKVVNKKKSPGLWVAMSGTSFATPIAASVVAILYQFYDANKAEINLEPGLDFKTVDSVRAILLKMSMAPTEDQHNYLNPWVGRDNYFNFSGEEKSGPVSFFAQMLRLCLGAWVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>E3QI64</accession>
    <name>E3QI64_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aminotransferase class-III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_05823</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094699.1">
        <property type="nucleotide sequence ID" value="XM_008096508.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QI64"/>
    <dbReference type="STRING" id="645133.E3QI64"/>
    <dbReference type="GeneID" id="24411188"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05823"/>
    <dbReference type="eggNOG" id="KOG1401">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016922_1_2_1"/>
    <dbReference type="OrthoDB" id="425114at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43713">
        <property type="entry name" value="GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43713:SF3">
        <property type="entry name" value="GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE 1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ30679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="428" mass="46685" checksum="1B22F9ECDD472996" modified="2011-01-11" version="1">MEVTAKPCPPAGTDLSASKIGQQLNDYIKKYVAENEKSHQVNKSASGSLPGGTTRSVLHYQPFPLAFLGGHDCHLTSMDGHEYLDFVSEYCAGMFGHSHPEIIAAVESVTKTGFTLGGPTPKEGELGALLVERFPSIDAIRFCNSGTEANTMAIATALHFNGRRKILVCENGYHGGTLSFSHGNPLILPHEFIYGRYNDIEFTRPKITDDIGVIIVEPMQGAAGMFEGSREFLNFLRDEATRVGAVLIFDEVITSRLKYGGLQEHHGITPDMTTIGKHFGGGFSFGAFGGRKEIMDLYDPESPRSLFHSGTWNNNVFSMTAGIAATKLLSREALERNNELGNKLRSDMAAAFASKDASIVTLTGFGSVIGVHFNGPLANKLLDLFFFYLLAKRIYVGHRGFLALNLTHGEEHISRVLDAVKEFCAEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIC2</accession>
    <name>E3QIC2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein 42</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_05881</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094757.1">
        <property type="nucleotide sequence ID" value="XM_008096566.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIC2"/>
    <dbReference type="STRING" id="645133.E3QIC2"/>
    <dbReference type="GeneID" id="24411246"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05881"/>
    <dbReference type="eggNOG" id="ENOG502S96H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076687_1_0_1"/>
    <dbReference type="OrthoDB" id="5854584at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039632">
        <property type="entry name" value="TMEM42"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31965">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31965:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ30737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="257" mass="27661" checksum="0D17FFDFE5EA5CB3" modified="2011-01-11" version="1">MLRQRQPAASVTAAPNHPQKAQIPTMAAATSTTLDNEHRPLLPRHEDDARSSSSQQATEAVDNDEATKSMAWARRNQWIVLAVASGACAAFNGVFAKLTTTDLTTAISQAISNFLHLQNIEGAFEVILRAVFFGLNLVFNGIMWTLFTKALAKGQSTTQVSIMNTSTNFVITAILGFAIFTEALPPLWWVGAAMLVAGNVIIGRKDEEADKPGGDYAPVPQQPGLATVPLDVPDEDKDSEDEDIVDLGDMNSSEHQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIP2</accession>
    <name>E3QIP2_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Aspartate aminotransferase</fullName>
            <ecNumber evidence="7">2.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLRG_05796</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:21824"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="EC" id="2.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3 7">Homodimer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="7">In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.1" evidence="7"/>
    <dbReference type="EMBL" id="GG697350">
        <property type="protein sequence ID" value="EFQ30652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094672.1">
        <property type="nucleotide sequence ID" value="XM_008096481.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIP2"/>
    <dbReference type="STRING" id="645133.E3QIP2"/>
    <dbReference type="GeneID" id="24411161"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05796"/>
    <dbReference type="eggNOG" id="KOG1412">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032440_1_2_1"/>
    <dbReference type="OrthoDB" id="6752799at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004069">
        <property type="term" value="F:L-aspartate:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006532">
        <property type="term" value="P:aspartate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000064">
        <property type="entry name" value="Aspartate aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000001">
        <property type="entry name" value="Aspartate aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000796">
        <property type="entry name" value="Asp_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006719">
        <property type="entry name" value="PRK09257.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879:SF55">
        <property type="entry name" value="GLUTAMATE OXALOACETATE TRANSAMINASE 1, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00799">
        <property type="entry name" value="TRANSAMINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 10" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="9">
        <location>
            <begin position="72"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFQ30652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="453" mass="49589" checksum="24A6C865A3047555" modified="2011-01-11" version="1">MPGDSSSSSSSSSPSSSSSSHQNNPTLSRIRSIASHIMPPVAATSFPADTVPQAPEDPLFGLMAAYRADESKDKVDLGIGAYRDNNAKPWVLPVVKKADEILRNDPELNHEYAPIAGIPAFTGKANELMLGADSPAIREKRTTSVQTISGTGAVHLGALFLAKFYKGNRTVYISNPTWANHNQIFGNVGLPIAQYPYFSKQTKGLDFDGLKSALSSAPERSIILLHACAHNPTGVDPTREQWKEIAALMRQKNHFPFFDCAYQGFASGNLAQDAWAVRYFIEQGFELLIAQSFAKNFGLYGERAGCFHFVTAPAPDAAQTTSRIASQLAILQRSEISNPPLYGARVAATVLNAPELFAEWEENLRTMSGRIIEMRKVLRAKLEELGTPGTWNHITDQIGMFSFTGLSETQVLKLRSDAHVYMTKNGRISMAGLNTRNVDYFAKAVDKVVRETQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>E3QIR0</accession>
    <name>E3QIR0_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA 4-demethylwyosine synthase (AdoMet-dependent)</fullName>
            <ecNumber evidence="4">4.1.3.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">GLRG_05892</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>N(1)-methylguanosine(37) in tRNA(Phe) + pyruvate + S-adenosyl-L-methionine = 4-demethylwyosine(37) in tRNA(Phe) + 5'-deoxyadenosine + L-methionine + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:36347"/>
            <dbReference type="Rhea" id="RHEA-COMP:10164"/>
            <dbReference type="Rhea" id="RHEA-COMP:10165"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64315"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="EC" id="4.1.3.44"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">tRNA modification; wybutosine-tRNA(Phe) biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TYW1 family.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.44" evidence="4"/>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094768.1">
        <property type="nucleotide sequence ID" value="XM_008096577.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QIR0"/>
    <dbReference type="STRING" id="645133.E3QIR0"/>
    <dbReference type="GeneID" id="24411257"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_05892"/>
    <dbReference type="eggNOG" id="KOG1160">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007952_1_2_1"/>
    <dbReference type="OrthoDB" id="271553at2759"/>
    <dbReference type="UniPathway" id="UPA00375"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904047">
        <property type="term" value="F:S-adenosyl-L-methionine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102521">
        <property type="term" value="F:tRNA-4-demethylwyosine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031591">
        <property type="term" value="P:wybutosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013917">
        <property type="entry name" value="tRNA_wybutosine-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034556">
        <property type="entry name" value="tRNA_wybutosine-synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13930">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT TRNA 4-DEMETHYLWYOSINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13930:SF0">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT TRNA 4-DEMETHYLWYOSINE SYNTHASE TYW1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08608">
        <property type="entry name" value="Wyosine_form"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00284">
        <property type="entry name" value="tRNA_wybutosine-synthesizing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01071">
        <property type="entry name" value="tRNA_wybutosine-synthesizing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11" id="KW-0456">Lyase</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="Flavodoxin-like" evidence="15">
        <location>
            <begin position="125"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="16">
        <location>
            <begin position="449"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="66"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="307"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="757"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="66"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="319"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="338"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="768"/>
            <end position="783"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EFQ30748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="783" mass="88381" checksum="AC19F7B9F020D875" modified="2011-01-11" version="1">MASYLEPAGFKDMLNNAHDAWQQIRIPVILFAAFGLLVLRFYLHSTKEKGELKAIPKVYNREESATKLVDQKKEAKTDGELSPPSPTAEPKAQKSNGPKRIKGGLVKRATSDSSRGEALARKIRPLVFFSSITANTSKIAKEYAERLEKELQKVATDTNCFFATPEVLDLAEVDFDDYFITPPKSEEDPAELFYLFLLPSYNIDTINDTFLEHLQETHHDFRIDTAPLSLLLGYSVFGFGDREGWPTEDDGFCFQAKEVDKWMAKLTGRKRAFPVGMGDTKRDYTERLSEWSEGVVDVLGMLAKTGSLGEGLPGSGAPEESDDESAEEDDDEVLIEDSEAKPEKLKNRKNIDDVEDLGRIMKSSNPDAGTKSRTVAAPIAVDFTTYGKTAQKKTPTSVVKEMVPKNSPTYASLTKQGYSIVGSHSGVKICRWTKSALRGRGSCYKYSFYGINSHQCMETTPSLSCSNKCVFCWRHGTNPVGTTWRWVVDPPELIFDGVKANHYSKIKMLRGVPGVRAERFAEAMRIRHCALSLVGEPIFYPYINEFLGMLHAERISSFLVCNAQHPDQLAALKAVTQLYVSIDASNKESLRKIDRPLHRDFWERFQRCLDILREKRFKHRTVFRLTLVKGFNVDDEVEGYAQLVEKGLPCFVEIKGVTYCGTSTASNAGLSMSNVPFYWEVAEFVKALEKRLNEKGLGYGIAAEHAHSCCVLLASERFYVDGKWHPRIDYQRFFELLEERGPDGDWRPEDYMGEATPEWATWGNGGFDPRDERVDRKGRKIER</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJ47</accession>
    <name>E3QJ47_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_06029</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697351">
        <property type="protein sequence ID" value="EFQ30885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008094905.1">
        <property type="nucleotide sequence ID" value="XM_008096714.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJ47"/>
    <dbReference type="GeneID" id="24411394"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06029"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_1_1"/>
    <dbReference type="OrthoDB" id="9971669at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17327">
        <property type="entry name" value="MFS_FEN2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000018">
        <property type="entry name" value="MFS transporter permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF53">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="268"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="313"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="337"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="362"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="396"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="431"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="40"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="463"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="463"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="479"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ30885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="488" mass="54436" checksum="38E9FB890F980826" modified="2011-01-11" version="1">MGPTIANDKYELAVYKESTTPFEWTEDEERTLRRKLDWHTVPLVTFLYLLCFLDRVNIGNARIQGMRNDINIEGYRFNWALSVFYIVYLLVEVPSNIILQRVGPRFYLPFLVVGFGLVSLCTAFITSFEGLIGIRVALGIFEGGAMPGFSFFLSSFYKREELLLRMGIFISSASLSGAFGGLLAAGLSRISPWGLSSIPIHTWRNIFFFEGLFTVIAGSLAPLWMPTGPATAYFLNDRERSIAVERLQRQQKANAEAKVNIQDIKSAVLCLHTYTCAFGFFLINITAQGISVFMPTILADLGWTATKAQLYSVPPYVVATITAIFVAWYSDKTRQRGIFLVACSMLAVIGFAILRFETQATIRYMALYFVAAGSFPCGPGFLCWAMNNSAGPSVRAVTSAYVVSIGTLGGIVATWTYTYKDAPKYFTGHTINLGGQSLTAMLAVFGIFYCMYENKSRATGKKDHRLEGLTNEEKDQLGHRHPSFRYMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJQ0</accession>
    <name>E3QJQ0_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLRG_06232</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697353">
        <property type="protein sequence ID" value="EFQ31088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095108.1">
        <property type="nucleotide sequence ID" value="XM_008096917.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJQ0"/>
    <dbReference type="GeneID" id="24411597"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06232"/>
    <dbReference type="HOGENOM" id="CLU_2996415_0_0_1"/>
    <dbReference type="OrthoDB" id="407275at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFQ31088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="57" mass="6041" checksum="914DB28CF2C17257" modified="2011-01-11" version="1">MIICGGSIFLDTGHLDSIVHPRQKTVCVSKGVLTGTLPLFLAAHGVFIPVRYCSDVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>E3QJZ8</accession>
    <name>E3QJZ8_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein bL32m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLRG_06330</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial ribosomal protein bL32 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697353">
        <property type="protein sequence ID" value="EFQ31186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095206.1">
        <property type="nucleotide sequence ID" value="XM_008097015.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QJZ8"/>
    <dbReference type="STRING" id="645133.E3QJZ8"/>
    <dbReference type="GeneID" id="24411695"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06330"/>
    <dbReference type="eggNOG" id="KOG4080">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129084_0_2_1"/>
    <dbReference type="OrthoDB" id="2014905at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051991">
        <property type="entry name" value="Mitoribosomal_protein_bL32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002677">
        <property type="entry name" value="Ribosomal_bL32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01031">
        <property type="entry name" value="rpmF_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21026">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L32, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21026:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL32M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01783">
        <property type="entry name" value="Ribosomal_L32p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EFQ31186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="135" mass="15008" checksum="ECAF0D58DB18ADB4" modified="2011-01-11" version="1">MAAIAMGAQPLRITSLLPRISAPAFTQTPRILSLYTRQVTNSILPLSFALPAFNLNIPAWLGGIWESILRAVPKKKTSHAKKRHRQMAGKALKDVKSLCKCPGCGQIKRQHIVCPHCLSKIKDLWRDENPSGKFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>E3QK30</accession>
    <name>E3QK30_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_06362</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697354">
        <property type="protein sequence ID" value="EFQ31218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095238.1">
        <property type="nucleotide sequence ID" value="XM_008097047.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QK30"/>
    <dbReference type="STRING" id="645133.E3QK30"/>
    <dbReference type="GeneID" id="24411727"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06362"/>
    <dbReference type="eggNOG" id="ENOG502SV4E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016775_1_0_1"/>
    <dbReference type="OrthoDB" id="5208775at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="201"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="430"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="112"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="143"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="449"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="465"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ31218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="570" mass="62454" checksum="0076DA0F588A140F" modified="2011-01-11" version="1">MSANAWPAGDGASHRSGQLSQKDIVLDRQMIKHLLGRYGPDELSRLIQETTCPQSDGASIVSSAQSSILSDDPSSVWDTQSVRTFSSDASSITGSIISNVSRGTSKILGRRSQSSSATAAAQAQAAQQDTTNPQEEIWNDVPTSSNTASDTASSTTSASKQKGAFMCGFCKEEDITKTCTRKNDLKRHIEDFHNVNAQWFCRHRGCQMVFDWQGAYKTHLKQAHGGSRMSLDEAKVNLCPQVVFACGFDNCLQVYEAQGDSDASSTFKEYVSHVVKHFDEGSNNGEWSYSARIRNLLRQNQVQAIWNESVWNEASRAALQWNPQTSGILRKRLECRHIGDVKLLVQYALMLGSDSGPIKFREDFVTPVIDTCTLHMPGHKSRQQSVAAPEPADPFSFKISRGANPALAAYMASQRRVYVPRQQRVVRPPQLHHPHQQVPSSNPMASHSRLSHSSHSSHHSHQQSHHNSQNHSSLGHFFQAPMESSIYDPNNNAQAFGSSSGAMHQNGIIADDMQSLRSMAAGTAESPDVEMQDPGMMADFSSHYAPHAASLASPAISGHTDGFFPPGQAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>E3QK67</accession>
    <name>E3QK67_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Obg-like ATPase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_06399</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GG697354">
        <property type="protein sequence ID" value="EFQ31255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095275.1">
        <property type="nucleotide sequence ID" value="XM_008097084.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QK67"/>
    <dbReference type="STRING" id="645133.E3QK67"/>
    <dbReference type="GeneID" id="24411764"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06399"/>
    <dbReference type="eggNOG" id="KOG1491">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018395_1_2_1"/>
    <dbReference type="OrthoDB" id="424823at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04867">
        <property type="entry name" value="TGS_YchF_OLA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01900">
        <property type="entry name" value="YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.300:FF:000001">
        <property type="entry name" value="Ribosome-binding ATPase YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000001">
        <property type="entry name" value="Ribosome-binding ATPase YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.300">
        <property type="entry name" value="TGS-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00944">
        <property type="entry name" value="YchF_OLA1_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004396">
        <property type="entry name" value="ATPase_YchF/OLA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023192">
        <property type="entry name" value="TGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013029">
        <property type="entry name" value="YchF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041706">
        <property type="entry name" value="YchF_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00092">
        <property type="entry name" value="redox-regulated ATPase YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23305">
        <property type="entry name" value="OBG GTPASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23305:SF11">
        <property type="entry name" value="OBG-LIKE ATPASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06071">
        <property type="entry name" value="YchF-GTPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006641">
        <property type="entry name" value="CHP00092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="TGS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="4">
        <location>
            <begin position="21"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="5">
        <location>
            <begin position="306"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="30"/>
            <end position="35"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ31255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="394" mass="43883" checksum="A0805D21DC2670F6" modified="2011-01-11" version="1">MPPKKQVVEEKILLGRPGNNLKSGIVGLANVGKSTLFQAITKCNLGNPANFPYATIDPEEARVIVPDERYDWLCEKYNPKSRVPANLTVYDIAGLTRGASTGAGLGNAFLSHIRAVDAIFQVVRCFDDAEIIHVEGDVNPTRDLEIISDELRLKDIEFTEKALENQKKKTRSGGKGLEHKKAMEEQATMEKILQFLKDGNEVRKGTWGPKEVEVINPLFLLTAKPVVYLVNLSEKDFIRKKNKYLPKVAEWVKEHAQGDPIIPISVSFEERLTRFETEEESKEEQKKVGAESALPKIVLQMRKVLNLGSFFTTGTDEVRQWTIRNGTKAPQAAGVIHTDFEKTFIQALVYNFTTLKELGSEAEVKAKGKVMTKGKDYVVEDGDILLIKAGAAKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKG2</accession>
    <name>E3QKG2_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_06494</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the fungal fucose-specific lectin family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697354">
        <property type="protein sequence ID" value="EFQ31350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095370.1">
        <property type="nucleotide sequence ID" value="XM_008097179.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKG2"/>
    <dbReference type="STRING" id="645133.E3QKG2"/>
    <dbReference type="GeneID" id="24411859"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06494"/>
    <dbReference type="eggNOG" id="ENOG502SHGW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_590527_0_0_1"/>
    <dbReference type="OrthoDB" id="5396810at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.70">
        <property type="entry name" value="Fucose-specific lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012475">
        <property type="entry name" value="Fungal_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07938">
        <property type="entry name" value="Fungal_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89372">
        <property type="entry name" value="Fucose-specific lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ31350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="472" mass="50741" checksum="0881362E48007C3A" modified="2011-01-11" version="1">MDSKTDYAMDKKDYSDLEVVMRQSMIPNDKCVIDSKFHEAMSSSSPVISPAPAYVAPVSMANSPIVPPSRTNTDDNASFSNPKAMAPQPEEKTILGLKRKTFILAAVGIAMLLVLILGLAIGLSTGKASSSDGAGGAPAVDSKSSVILENSSLAATNWTDNNNVGRAAVFYQDKFNGLNVMLFDSLSGSWTKRNVTASVMNSSSIPALDVMPGTPLACVTNKFQVSLYYLQRDNTISEIYSPNPVSGQWLPGSLNPTLNPQASNGSRLAAYWQVCPSCTDTLLLAYESNGQVQLLNSTKNQWQVMPSISTKVVPGSGLSMNPFTDFNGAGPTGTDANAIRVYQSASDNLMEVISGPLTDRRWEIGNFGNPLTTNVPTNPAPEIASLSFGSTGWTESLTTYLTANGMLVSAHWNDTAWTVRPPTLDKHFGNATAIATTQAQRYYTLVDGSIHQYRVEASADPFMWYHVNQLMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKJ4</accession>
    <name>E3QKJ4_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Late endosomal/lysosomal adaptor and MAPK and MTOR activator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLRG_06526</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697355">
        <property type="protein sequence ID" value="EFQ31382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095402.1">
        <property type="nucleotide sequence ID" value="XM_008097211.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKJ4"/>
    <dbReference type="GeneID" id="24411891"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06526"/>
    <dbReference type="eggNOG" id="ENOG502SGDI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108580_0_0_1"/>
    <dbReference type="OrthoDB" id="5299893at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045121">
        <property type="term" value="C:membrane raft"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071986">
        <property type="term" value="C:Ragulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071230">
        <property type="term" value="P:cellular response to amino acid stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043410">
        <property type="term" value="P:positive regulation of MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032008">
        <property type="term" value="P:positive regulation of TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001919">
        <property type="term" value="P:regulation of receptor recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028209">
        <property type="entry name" value="LAMTOR1/MEH1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15454">
        <property type="entry name" value="LAMTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01262">
        <property type="entry name" value="LAMTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0519">Myristate</keyword>
    <keyword evidence="4" id="KW-0564">Palmitate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EFQ31382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="159" mass="17564" checksum="0B2CC0276F6D0459" modified="2011-01-11" version="1">MGICASCLGRGNKDVYDEDEESRLLYDDPNNVHYGSFGEQSVNGQEDPMEVQRETEALQRVVAKTSDNMVDIFEIAPQDHAHRPAPTTFAYAGQEARIVRYQHLLSKLASKDEAPAGVQVDWLPQEDDTIEMQRGVPVLKVESDKPLVGTFADAAAAMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>E3QKY5</accession>
    <name>E3QKY5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">BNR/Asp-box repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_06812</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697356">
        <property type="protein sequence ID" value="EFQ31523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095543.1">
        <property type="nucleotide sequence ID" value="XM_008097352.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QKY5"/>
    <dbReference type="STRING" id="645133.E3QKY5"/>
    <dbReference type="GeneID" id="24412177"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06812"/>
    <dbReference type="eggNOG" id="ENOG502QW46">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036301_0_1_1"/>
    <dbReference type="OrthoDB" id="2130735at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38792">
        <property type="entry name" value="BNR/ASP-BOX REPEAT DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_7G06430)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38792:SF3">
        <property type="entry name" value="BNR_ASP-BOX REPEAT DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_7G06430)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110296">
        <property type="entry name" value="Oligoxyloglucan reducing end-specific cellobiohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180564" evidence="1">
        <location>
            <begin position="22"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="379" mass="42525" checksum="5AEA546246A01AE4" modified="2011-01-11" version="1">MMIRSALIAAVGALTCGIASALETFERNLIFQPPDNYTDPRVLYPRTVQLIDGRLLATWENYSPEPPLVWFPIYESLDGGLTWEEVGQVHDQVNNWGLRYQPFLYELRQDFAGFPVGTILLAGNSIPTDLSETQIDLYASRDKGRTWEFLSHVARGGRAIPSNEETPVWEPFILIFEDDLILYYADQRSSEHGQEISHQTTKDLKNWSDVVIDVTYPRYTDRPGMPFITQLANGDYMYTFEWGGADIITPYSFPIYYRIAKDPRKFADAPDRYIKSTNGGVFPINSPNVVWSPVGGCNGTIVVSSNSAPLFINRRGGDPDAWVAYDSPEAGAYTRNLRVFEEDPDYLIIMGAGVLPPSTTNKVTVSVLKLSNLLGLKQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLM7</accession>
    <name>E3QLM7_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLRG_06740</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="2"/>
    <dbReference type="EMBL" id="GG697357">
        <property type="protein sequence ID" value="EFQ31765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095785.1">
        <property type="nucleotide sequence ID" value="XM_008097594.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLM7"/>
    <dbReference type="STRING" id="645133.E3QLM7"/>
    <dbReference type="GeneID" id="24412105"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06740"/>
    <dbReference type="eggNOG" id="KOG0800">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050242_0_1_1"/>
    <dbReference type="OrthoDB" id="444265at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006513">
        <property type="term" value="P:protein monoubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46077">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE TOPORS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46077:SF1">
        <property type="entry name" value="TOP1 BINDING ARGININE_SERINE RICH PROTEIN, E3 UBIQUITIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="39"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="96"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="295"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="100"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="337"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFQ31765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="360" mass="42197" checksum="63B4F5A101D353E3" modified="2011-01-11" version="1">MSPEATAGGNPKPQDLHSAVLQTTLQEISSRPTELQDCCVICLEEVTERCEAQPCHHHNFDYLCLVTWLEQQAACPLCKTEVKEVRYDFSDDQTQWKTYKAPERPQEKPKAAGASPPSQQARRFYSQARPRYSRSHARPTRTFTPSQNEAIARRRTVYRDQMYSLHVGSNRISRYRDLTPQLFASDAELVSRARTFLRRELQVFEFLSPDNDALPQDADPVRRRRANNAEFLLEYIIAILKTVDMQGSMGQAEELIQEFLGRENTRLLLHELRAWLRSPYMTLESWDRAVQYPDVAPKRRRRSQSPSAADRAESSRSADGIYPSRWRRDERRRHRREPRESRRSRNDERLREATERYIVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLN8</accession>
    <name>E3QLN8_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLRG_06751</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697357">
        <property type="protein sequence ID" value="EFQ31776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095796.1">
        <property type="nucleotide sequence ID" value="XM_008097605.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLN8"/>
    <dbReference type="STRING" id="645133.E3QLN8"/>
    <dbReference type="GeneID" id="24412116"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06751"/>
    <dbReference type="eggNOG" id="ENOG502RSQP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008206_0_0_1"/>
    <dbReference type="OrthoDB" id="5354458at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056687">
        <property type="entry name" value="DUF7785"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057199">
        <property type="entry name" value="DUF7877"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25009">
        <property type="entry name" value="DUF7785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25289">
        <property type="entry name" value="DUF7877"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7877" evidence="3">
        <location>
            <begin position="59"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7785" evidence="2">
        <location>
            <begin position="456"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="566"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="683"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="845"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="569"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="599"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="627"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="690"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="716"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="741"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="775"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="895"/>
            <end position="913"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFQ31776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="913" mass="99761" checksum="C29983C5B30B70AE" modified="2011-01-11" version="1">MAQSDSVRANGIPGPDHAESPQPVVPVKRKRDTDDDGEEISTDGPEKMEVDGELPKEDHKPLIKDYFTVLSSFDASPSILKRRLPEPESEQPDAKRQKSAESAATIADKVTHDAYSHVDELAADLVEAVQDQLRELQCANADDDAVNKNIDGVAVAQTKRFKDKAMDLLRREISYPRSAVNITNTKPDVESAMGNAVLTVFGNAPHGKQLFSSLPKKASGKEDSAATASTFDLPPGVSTSYIVPSRQVERAPTLGDLFSSSRPLPPLQPPKQPKPVAKGNVLGFYHPEPAQKSKYFNDSYSSKKLAVGYYLDYTNAAPSAKTKTKQRERAQSLAGHRPSSTEMEVNEMESLFRSAFSSFAPCRDDSGSVVPSSHAGRMYWQLTGQRNFNRMIESELREIEDEKTTEKPVEKEAVTGQVDEEFVNEAIEKWDEWLVDPALQDMNDVLAKPKDKDPADKEADDLLDEVTDMIETLLSYQRIRNLTLPSSQNRYAGDPVNGDLLSHGAVLTPTEEETATYEALKAQLSLIINTLPPYAVAKLNGGQLEQLLISTKLEVRTDQYKGVMEDDAASQARMRQQQSVATAAPTNRPAPHRTPSASTPYGTQYGSGQYGTPTRTPSIAPTNYYRPGQQPAMPPQQGSVPRPGGVPHQMSHTPQPRPGQPGNYRPTNGYTNYAQHVGKAQTPYGHQGVQYGSQQRPPQYPGYPGTPQHGTPNARFQQPYQQSFQQQPTTPSQGYGGYYANGSNMQQRTMSPQIPAAQYQSSPTPHQQARYYGSTPHQTMPGTPPINRQQYANGSHLPQQPLNSLTPGYNAAVARADQQRLHAEQARYRAAAQQTSAAFGTKIQGTQEGAMPGDDPSSQGSPYNASMRARMAAGGTPKPQSPVGKATNGTPPIPHKVTPVPIPVIPQQQRKPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QLW3</accession>
    <name>E3QLW3_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kelch domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_06995</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095871.1">
        <property type="nucleotide sequence ID" value="XM_008097680.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QLW3"/>
    <dbReference type="STRING" id="645133.E3QLW3"/>
    <dbReference type="GeneID" id="24412360"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_06995"/>
    <dbReference type="eggNOG" id="KOG4441">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004253_10_0_1"/>
    <dbReference type="OrthoDB" id="45365at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45632:SF24">
        <property type="entry name" value="GALACTOSE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45632">
        <property type="entry name" value="LD33804P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180593" evidence="1">
        <location>
            <begin position="18"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="346" mass="36204" checksum="99042BB22B9E439F" modified="2011-01-11" version="1">MRSIILLLAAVVSAASGGTLRQVDQNWEVLSPIPIAPRQEHSVVALSGTRLAIAGGILPNLDNGVGFNTTAFIQFYDIHTDSWSEPIDAPIEVNHPNVAAVDGEIFLLGGLAVASDGAWRAFADSWKYHPSTGEWTALPPIPAGKAAGSATIGVLGNTIVLAGGMRTLEPIGVEGEQDTVDFVSMFDTKSCTWSHVPEAASVLPEGRDHAAGSVIGSRFYVLGGRLRGQYNVKDTVFVLDVDDMEAGWTTQGARMPTARGGVVGGNVGGKVYVFGGEGNTAEGSDGVFDNVEVYDVEFDTWQELGPMRLPRHGGAAATVGGKIYLPGGGIREGGSPVNVTDVFIVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>E3QM84</accession>
    <name>E3QM84_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLRG_07116</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697358">
        <property type="protein sequence ID" value="EFQ31972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008095992.1">
        <property type="nucleotide sequence ID" value="XM_008097801.1"/>
    </dbReference>
    <dbReference type="STRING" id="645133.E3QM84"/>
    <dbReference type="GeneID" id="24412481"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07116"/>
    <dbReference type="eggNOG" id="ENOG502S79B">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_234524_0_0_1"/>
    <dbReference type="OrthoDB" id="4850289at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="750"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="908"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1323"/>
            <end position="1548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1611"/>
            <end position="1796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="754"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="949"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1323"/>
            <end position="1353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1387"/>
            <end position="1396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1436"/>
            <end position="1445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1451"/>
            <end position="1468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1514"/>
            <end position="1523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1531"/>
            <end position="1546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1640"/>
            <end position="1698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1705"/>
            <end position="1716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1717"/>
            <end position="1729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1772"/>
            <end position="1783"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFQ31972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1796" mass="202159" checksum="28DEEE4FAB4E4842" modified="2011-01-11" version="1">MAELQMEALEPQKRYNALIRPTDDDWISVHDRFRDLLSQPTLRTEQVLESYFTEYERKLFMPATEPLSLRNCQEDNTRRYRSLTTGRFKGWHLSLATKFTMLYFGLPVEPILSELFETAKPDFDVDDGDELCDVEVRPPLNFLTAHDQRNYGRDYMRGMELQFCTIPVPASQMPKGTAAQELNLRGGGLDDDNDLRMLDGRMYENAGQGRQPEVVGETDDDVSDASASATSGRATKVRFEEKPVETPRAHDCSPLYGYQGRIMFKPGDLSTFEAASRKLLSLRRREGCDLVLVEFDQVSRQARTSFHDNIPLNPNGQVANILRQKANSGIETVWFVLRRGEREPNEWEPRKALFSSSLVKLSHLDEGHENVSYFNLPSHKPLFGGFKPSESIRSFLQPWGANQYMPFLTTAQQVLTGTPDRPGASHCDIEITAEDGQTGADSTYWYGGLEMHASLLHMMHPSVAKGSSFVVRSCPLPEDCIVFYLPGGIIKSAKKSENRQCHRQAGSKDPYPDALQKIKAMTEGLDMPQDISYRIWRGTDYFNPLIKNPVEQYKPVSWSPRGGNFQKQNQDQATLSKLIVNAVDNVREPCRFFVIQPFYGRNDSRTMETPSNSNGSAAFQGGSDTMETFKAKVQSLYRDDPKVQYDPERDSVLIAPIYKKDGLPRQWNPVRFVLRPDAANYELIMVGRLSVAQIMRVTVLNNGDLDFVKGVAKEMDEGNQWGPRYGQVTPLRLELSLPPVAQPVQNQHLAAQRQRGEVSRETSRVPKQNLRETSWETQPSIYDNGIYHPSFPINAPPVESVMRVGGGRLPMITRNVLTVTEQREMQGALWKTRGMVLDRISKCPYEGCEFSHRVDEDEKLVKHLEENHTGQKCPWCDDRLFSFWSRKQKEAHYKTAHGDQLRKMLGQAEKSVPRPQPSRTSTAGGLHNVSVPLTSSISPFKIMERARPPSGPLPRPSPPPKASEKEADYRYCDRCGRDHAQLTGQAERKHHDRVCVPLAEGGGLCTFCEACGDAEWETEQDAKEFAPFDVYPHKCRGTVHLNKPHCKRCGLSMKDMTDMEIDKHRTYCAGYCGTMGCFCPYCQRHFVKNGTQDPIKDVKKHILECKKREHGTATPYEIYPETYWKDQDAPTDPLYVGQDASSMLVRKQRRPNGPTRYLSFPLLWYERSGPVPTQDPPSECKIAGCREPLFGLTPSEVLGHFETNHGGQPQKQCPLCHLSFMKAKDESEEERNPGEVEDRQAQVAHMECHVYQLWDRLASGGPPPPIIAREPFYAGHSLWDPSNERALDRRDKRCPHFDKCGAMVGFMNQRQWNHHMETAHSAEDFELRAPPRDRTTEMQITFEERRRQRERQGKPPMAGQVRPVTKPKELGHRAATGASERTPMPAAPATQPQNQPGAGGGQSRGDAPGSSRAMPLGPEAARPEEAVPRAGHPEGGSSNKQTETQAGGPPRKIEGPAAKPKDHTEKPRKPAGKQASKARSKPALGQKPSSGSKPKTAAPLPSYDAGDDLYCSRCFRKAPKRGSKAQIPDGDPTRQEQIDAHSDPARSCRIRPQLGRVKYNHNGEPLLPSRVGWIPKGNLKFKDIRDAFVRDNPQLETTMCPTDAQWKRTYSKWAHDPNNENNQDVWGMPYRPREDQYAGDSEEDDGDEAYVQGSEDEGEEDEDEDMDEDVEESEGEEGAGQEGEQEDQGGVDDSDDGAEGNADSRRRRKRKLFRGVHTRDPTYRDRGDGDNLSEGDPSELVPESGDERDGSTGSGGGKRKRHAMQSMGQAQADEKTQTQERERKKARVSEGGQDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>E3QME4</accession>
    <name>E3QME4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_07176</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697359">
        <property type="protein sequence ID" value="EFQ32032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096052.1">
        <property type="nucleotide sequence ID" value="XM_008097861.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QME4"/>
    <dbReference type="GeneID" id="24412541"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07176"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_27_2_1"/>
    <dbReference type="OrthoDB" id="5086884at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718:SF11">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="67"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="116"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="287"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="323"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="351"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="376"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="416"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="451"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="29"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ32032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="509" mass="55425" checksum="5B573C4FCBC1EE27" modified="2011-01-11" version="1">MAIPDEKEQERLGRQRPEVFSSTLQEVGFCASILLSNIMAEFLISGFNVLLPSLIKELNFSPEDKTWPSSVFSLVAGAFLLPFGRLSDMHGGFLVFLAGNVWMATWSLIGGFSQNYVMLVVCRALQGLGAAAFLPSGISLLGSVYRPGRRKNLVFSLYGGCAPLGFFTGILVAGVSGQFLRWSWFFWIGCMLLTIVCLLIFFCVPRQMYPARMPMDWWGCGTSIPGLMLLVYAITDSPHVEKGWASPQILVTFLLGLIFLAAFVYVEGWVSPAPLLSAQLFAPKYTIALFCCLFIAFGSFGIYLLYASFYIETILHIEPLLTAAWFAPLAIGGIIIAIVGSVVLHKLTGTVLLLLSVAGFLVSSLLFIFIPRDPNYWAWVFPAMTCATIGIDIMYNVSNIFITTSMKSDQQGMAGACVNALLFLGMSFFLGWADLASVAGARENLESGYKIALVMGAGCAGASILIIAFCIRVGRAKGDMTADEREELERLGAAGSDSTLRQENEGSYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>E3QMZ4</accession>
    <name>E3QMZ4_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Armadillo repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLRG_07376</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="GG697360">
        <property type="protein sequence ID" value="EFQ32232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096252.1">
        <property type="nucleotide sequence ID" value="XM_008098061.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QMZ4"/>
    <dbReference type="STRING" id="645133.E3QMZ4"/>
    <dbReference type="GeneID" id="24412741"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07376"/>
    <dbReference type="eggNOG" id="KOG1293">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002741_2_0_1"/>
    <dbReference type="OrthoDB" id="5559898at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034657">
        <property type="term" value="C:GID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038739">
        <property type="entry name" value="ARMC8/Vid28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15651">
        <property type="entry name" value="ARMADILLO REPEAT-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15651:SF7">
        <property type="entry name" value="ARMADILLO REPEAT-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="589"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="600"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="617"/>
            <end position="626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EFQ32232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="1032" mass="112406" checksum="28DA11F35BC3B99A" modified="2011-01-11" version="1">MTRSSNLPILSQLLSARSYAEQTGALRALKNDIVGHAQKKEMWAGLGALNPIVQILNAARSPAKVNGKDTRPGASPRYVSEEENVRLQALQLLASFANGGTAFVEPLLVAGALPAVLDNICPVSNAPLLVTAALRVLLNIIEAAALAQPTSPVDTQALAEAIFATEHIDSFNSILSSTSTTSEQQTQVILVANIISQSCRDERHQLAMASQGVLDSLATRLASIAVALGHVIPYAEVLGRVDRMSDFIPEPAPSSSTLAPILEALATIISDSRFRACMLLCSPAIMAIFPAMKFTPSKEVRAPWNSLDVSGLGFARQQSLSAVDYLLPAVPIHQGRVSGSQQSHFPALGSSEARERARSAATKYTSTASVWEASRFELFGNEGEPEEEQESPLIPWLIVLVRSRQNMERLMAANLLTSLFRSGFGIKCLREASLGLLVVPVLMDMLDQLQSAPPIVKSPLVDADTALRWAMLEKTPAILARMITDSEPLQKAAFDCGAVKCYSKLLKDAYEPIPASAYAKVWSPQVDHAMEAEDTSPSCALGPEGQPPLLAHRIRMRESALKAIGALAAGKDEYRKAFVEQDVVAHIVQSLSPTPGKPSNPKDRSKPNEPDGPVGDGSSSDHNSGYGSNPLPVLIAGCHAVRMLSRSVSILRTSLVDYAVAVPLFRFLRHPDADVQIAATAAICNLVTEVSPMREVLADRGVMKILCEHAHSLNPALRLNALWALKHFVHAVDPETKKHCLEELESGWLVQLICDDTEDDALFLARYKMDKQNAVDSGDDMDGDIEMDQADPLSKSWISSTMPPQDADGKRSAKLRQAEARLAALREAEINPLRKARNDDLAIQEQGLDFIRNMIGAAGSGSNSESPSDTTEMIDYLFSELGQDRFFDILARKLQAKVLHPTSRRSAGSARETRVLYPQAKIIEAVVFILVHMAASIPRHRQLVIAQTDLLKLLANHFNSKDKEVRVALCHLISNLTWQDDESDTRACAQRAYELKKLGFLTKLEGLEDDCELDVRERAKSAVWQMKQVSSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>E3QNF5</accession>
    <name>E3QNF5_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tat pathway signal sequence</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLRG_07537</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GG697361">
        <property type="protein sequence ID" value="EFQ32393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096413.1">
        <property type="nucleotide sequence ID" value="XM_008098222.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QNF5"/>
    <dbReference type="GeneID" id="24412902"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07537"/>
    <dbReference type="eggNOG" id="ENOG502QVV4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005562_3_0_1"/>
    <dbReference type="OrthoDB" id="3142841at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052979">
        <property type="entry name" value="Adenylate-forming_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33927:SF5">
        <property type="entry name" value="ENZYME, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G01222)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33927">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="190"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="227"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="265"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="294"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EFQ32393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="574" mass="62577" checksum="50C97C3012FE2E37" modified="2011-01-11" version="1">MSFRTSSSVTLPVGEDVEQDHTSMTRGNEHTSGHNVTPPARAFLLSQNSSSRTLVARESTNQSHETSWTIASSTDVDDDEDDEDGVVVPSKKGTRTYRYLRWNFGSVYRRIFTLAFIGNMAALVLVVVRSLLGGPSSRLTPGTCATAVSANLLAALFIRNEHTVNAMFKVFVLFPAARTPLAIRRALAKVYSYGGIHSGCGVASFFWFVAFLVVITGDFANPNAVRAYILLDSYLICALLAAIIGFAHPRARVLLHNWFEGTHRFLGWSVILLFWALVMMLAEDSSSNSAAAVPYAAALVATPSFWMLIAITLLVAYPWTRLRLRDVEAEAMSDHVVKLNFDYADVHYGQAVRLTDAPLRETHAFAVIPNPAAPRTADDVEKARQGLSNAGKKGFSVLVSNAGDWTDKIIRNPPKKMWTRGVPQYGVLRVASLFEPCIVVATGSGIGPCLSLFVQKPDHPVRIVWSTQRPAETYGQAVIDTLYRADPDAVIIDTKKTGRPDLVAITYRIWETSRRRALGLAQNEGGVAAAAAAVAKNTGPCEAVVIISNQKVTRKVVYGLESRGIPAYGAIFDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>E3QP46</accession>
    <name>E3QP46_COLGM</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Glycosyltransferase sugar-binding region containing DXD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLRG_07648</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum graminicola species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Nat. Genet." volume="44" first="1060" last="1065">
            <title>Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses.</title>
            <authorList>
                <person name="O'Connell R.J."/>
                <person name="Thon M.R."/>
                <person name="Hacquard S."/>
                <person name="Amyotte S.G."/>
                <person name="Kleemann J."/>
                <person name="Torres M.F."/>
                <person name="Damm U."/>
                <person name="Buiate E.A."/>
                <person name="Epstein L."/>
                <person name="Alkan N."/>
                <person name="Altmueller J."/>
                <person name="Alvarado-Balderrama L."/>
                <person name="Bauser C.A."/>
                <person name="Becker C."/>
                <person name="Birren B.W."/>
                <person name="Chen Z."/>
                <person name="Choi J."/>
                <person name="Crouch J.A."/>
                <person name="Duvick J.P."/>
                <person name="Farman M.A."/>
                <person name="Gan P."/>
                <person name="Heiman D."/>
                <person name="Henrissat B."/>
                <person name="Howard R.J."/>
                <person name="Kabbage M."/>
                <person name="Koch C."/>
                <person name="Kracher B."/>
                <person name="Kubo Y."/>
                <person name="Law A.D."/>
                <person name="Lebrun M.-H."/>
                <person name="Lee Y.-H."/>
                <person name="Miyara I."/>
                <person name="Moore N."/>
                <person name="Neumann U."/>
                <person name="Nordstroem K."/>
                <person name="Panaccione D.G."/>
                <person name="Panstruga R."/>
                <person name="Place M."/>
                <person name="Proctor R.H."/>
                <person name="Prusky D."/>
                <person name="Rech G."/>
                <person name="Reinhardt R."/>
                <person name="Rollins J.A."/>
                <person name="Rounsley S."/>
                <person name="Schardl C.L."/>
                <person name="Schwartz D.C."/>
                <person name="Shenoy N."/>
                <person name="Shirasu K."/>
                <person name="Sikhakolli U.R."/>
                <person name="Stueber K."/>
                <person name="Sukno S.A."/>
                <person name="Sweigard J.A."/>
                <person name="Takano Y."/>
                <person name="Takahara H."/>
                <person name="Trail F."/>
                <person name="van der Does H.C."/>
                <person name="Voll L.M."/>
                <person name="Will I."/>
                <person name="Young S."/>
                <person name="Zeng Q."/>
                <person name="Zhang J."/>
                <person name="Zhou S."/>
                <person name="Dickman M.B."/>
                <person name="Schulze-Lefert P."/>
                <person name="Ver Loren van Themaat E."/>
                <person name="Ma L.-J."/>
                <person name="Vaillancourt L.J."/>
            </authorList>
            <dbReference type="PubMed" id="22885923"/>
            <dbReference type="DOI" id="10.1038/ng.2372"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M1.001 / M2 / FGSC 10212</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Endomembrane system</location>
            <topology evidence="10">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 32 family.</text>
    </comment>
    <dbReference type="EMBL" id="GG697363">
        <property type="protein sequence ID" value="EFQ32634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_008096654.1">
        <property type="nucleotide sequence ID" value="XM_008098463.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="E3QP46"/>
    <dbReference type="STRING" id="645133.E3QP46"/>
    <dbReference type="GeneID" id="24413013"/>
    <dbReference type="VEuPathDB" id="FungiDB:GLRG_07648"/>
    <dbReference type="eggNOG" id="ENOG502QW2I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022381_5_1_1"/>
    <dbReference type="OrthoDB" id="411251at2759"/>
    <dbReference type="Proteomes" id="UP000008782">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000136">
        <property type="term" value="C:mannan polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000009">
        <property type="term" value="F:alpha-1,6-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.20:FF:000002">
        <property type="entry name" value="Initiation-specific alpha-1,6-mannosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007577">
        <property type="entry name" value="GlycoTrfase_DXD_sugar-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039367">
        <property type="entry name" value="Och1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31834">
        <property type="entry name" value="INITIATION-SPECIFIC ALPHA-1,6-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31834:SF1">
        <property type="entry name" value="INITIATION-SPECIFIC ALPHA-1,6-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04488">
        <property type="entry name" value="Gly_transf_sug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003180781" evidence="12">
        <location>
            <begin position="24"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="42"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="42"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="61"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00060399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EFQ32634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000008782"/>
        </source>
    </evidence>
    <sequence length="372" mass="42434" checksum="DDD204EC90DC2AC1" modified="2011-01-11" version="1">MLTPRRAIAVAAFLLVVFYLISSSHDTSPAVVKPVVAASNHDTAGSKKLSSTPASTDEIKPSAPKAAAQKPMMDMSKMSLYDKLAYQYPYDPETRFPAYIWQTWKWTPADEEFNFREQEASWSEQHPGFVHEVITDKVAVNLLRLFYASVPEVLNAYDALPLPVLKADFFRYLILLARGGIYSDIDTYAIRSALEWIPERIPRESVGLVTGIEADPDRPDWKDWYSRRIQFCQWTIQSKPGHPILREIVVRITEETLKRKKAGKLNNIIDKNVVELTGPAVWTDTIFDYFNDPRYFDMKNSKGPIDWKNFTGMETSKKVGDVVVLPITSFSPGVQQMGAKDYDDPMAFVKHDFEGTWKPEELRHIGEQTEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-01-11" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>E3QP65</accession>
    <name>E3QP65_COLGM</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">cAMP-dependent protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLRG_07797</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)</name>
        <name type="common">Maize anthracnose fungus</name>
        <name type="synonym">Glomerella graminicola</name>
        <dbReference type="NCBI Taxonomy" id="645133"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dika
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